LOCUS       DAFELK010000001       145749 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFELK010000001
VERSION     DAFELK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 145749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 145749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..145749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.001"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(531..2027)
                     /gene="lysS"
                     /locus_tag="LP433_000001"
     CDS             complement(531..2027)
                     /gene="lysS"
                     /locus_tag="LP433_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBL2004204.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="LP433_000002"
     CDS             complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="LP433_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBL2004205.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="LP433_000003"
     CDS             complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="LP433_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBL2004206.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="LP433_000004"
     CDS             complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="LP433_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBL2004207.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="LP433_000005"
     CDS             complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="LP433_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBL2004208.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="LP433_000006"
     CDS             complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="LP433_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBL2004209.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8558..9028)
                     /locus_tag="LP433_000007"
     CDS             complement(8558..9028)
                     /locus_tag="LP433_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBL2004210.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9074..9499)
                     /locus_tag="LP433_000008"
     CDS             complement(9074..9499)
                     /locus_tag="LP433_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBL2004211.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9566..9835)
                     /locus_tag="LP433_000009"
     CDS             complement(9566..9835)
                     /locus_tag="LP433_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBL2004212.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9846..11441)
                     /locus_tag="LP433_000010"
     CDS             complement(9846..11441)
                     /locus_tag="LP433_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2004213.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="LP433_000011"
     CDS             complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="LP433_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBL2004214.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14994..15554)
                     /locus_tag="LP433_000012"
     CDS             complement(14994..15554)
                     /locus_tag="LP433_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBL2004215.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15907..16881
                     /locus_tag="LP433_000013"
     CDS             15907..16881
                     /locus_tag="LP433_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL2004216.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17051..18451
                     /locus_tag="LP433_000014"
     CDS             17051..18451
                     /locus_tag="LP433_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBL2004217.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18529..19251)
                     /locus_tag="LP433_000015"
     CDS             complement(18529..19251)
                     /locus_tag="LP433_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2004218.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19330..19836)
                     /locus_tag="LP433_000016"
     CDS             complement(19330..19836)
                     /locus_tag="LP433_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL2004219.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19959..21758
                     /locus_tag="LP433_000017"
     CDS             19959..21758
                     /locus_tag="LP433_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBL2004220.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21826..23400)
                     /locus_tag="LP433_000018"
     CDS             complement(21826..23400)
                     /locus_tag="LP433_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL2004221.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23655..24164)
                     /gene="mreD"
                     /locus_tag="LP433_000019"
     CDS             complement(23655..24164)
                     /gene="mreD"
                     /locus_tag="LP433_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBL2004222.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24168..25022)
                     /gene="mreC"
                     /locus_tag="LP433_000020"
     CDS             complement(24168..25022)
                     /gene="mreC"
                     /locus_tag="LP433_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBL2004223.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25177..25815)
                     /locus_tag="LP433_000021"
     CDS             complement(25177..25815)
                     /locus_tag="LP433_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBL2004224.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLEGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25816..26466)
                     /locus_tag="LP433_000022"
     CDS             complement(25816..26466)
                     /locus_tag="LP433_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL2004225.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26479..27378)
                     /gene="rsgA"
                     /locus_tag="LP433_000023"
     CDS             complement(26479..27378)
                     /gene="rsgA"
                     /locus_tag="LP433_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBL2004226.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27543..29612)
                     /gene="pknB"
                     /locus_tag="LP433_000024"
     CDS             complement(27543..29612)
                     /gene="pknB"
                     /locus_tag="LP433_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBL2004227.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29609..30349)
                     /locus_tag="LP433_000025"
     CDS             complement(29609..30349)
                     /locus_tag="LP433_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBL2004228.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30362..31720)
                     /gene="rsmB"
                     /locus_tag="LP433_000026"
     CDS             complement(30362..31720)
                     /gene="rsmB"
                     /locus_tag="LP433_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBL2004229.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31720..32658)
                     /locus_tag="LP433_000027"
     CDS             complement(31720..32658)
                     /locus_tag="LP433_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBL2004230.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKKLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32651..33142)
                     /gene="def"
                     /locus_tag="LP433_000028"
     CDS             complement(32651..33142)
                     /gene="def"
                     /locus_tag="LP433_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL2004231.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33157..35565)
                     /gene="priA"
                     /locus_tag="LP433_000029"
     CDS             complement(33157..35565)
                     /gene="priA"
                     /locus_tag="LP433_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBL2004232.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35818..36123)
                     /locus_tag="LP433_000030"
     CDS             complement(35818..36123)
                     /locus_tag="LP433_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL2004233.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36128..36742)
                     /gene="gmk"
                     /locus_tag="LP433_000031"
     CDS             complement(36128..36742)
                     /gene="gmk"
                     /locus_tag="LP433_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBL2004234.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37229..37513)
                     /locus_tag="LP433_000032"
     CDS             complement(37229..37513)
                     /locus_tag="LP433_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004235.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37531..38421)
                     /locus_tag="LP433_000033"
     CDS             complement(37531..38421)
                     /locus_tag="LP433_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBL2004236.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38441..38659)
                     /locus_tag="LP433_000034"
     CDS             complement(38441..38659)
                     /locus_tag="LP433_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBL2004237.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38629..40329)
                     /locus_tag="LP433_000035"
     CDS             complement(38629..40329)
                     /locus_tag="LP433_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBL2004238.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40596..41369
                     /locus_tag="LP433_000036"
     CDS             40596..41369
                     /locus_tag="LP433_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004239.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41450..42019)
                     /gene="thiT"
                     /locus_tag="LP433_000037"
     CDS             complement(41450..42019)
                     /gene="thiT"
                     /locus_tag="LP433_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBL2004240.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42085..42187)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42193..43164)
                     /locus_tag="LP433_000038"
     CDS             complement(42193..43164)
                     /locus_tag="LP433_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL2004241.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43258..44631)
                     /gene="glmU"
                     /locus_tag="LP433_000039"
     CDS             complement(43258..44631)
                     /gene="glmU"
                     /locus_tag="LP433_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBL2004242.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45134..45952)
                     /gene="purR"
                     /locus_tag="LP433_000040"
     CDS             complement(45134..45952)
                     /gene="purR"
                     /locus_tag="LP433_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBL2004243.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46119..46943)
                     /locus_tag="LP433_000041"
     CDS             complement(46119..46943)
                     /locus_tag="LP433_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL2004244.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46916..47596)
                     /locus_tag="LP433_000042"
     CDS             complement(46916..47596)
                     /locus_tag="LP433_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL2004245.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47619..48557)
                     /locus_tag="LP433_000043"
     CDS             complement(47619..48557)
                     /locus_tag="LP433_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBL2004246.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48802..49665)
                     /locus_tag="LP433_000044"
     CDS             complement(48802..49665)
                     /locus_tag="LP433_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBL2004247.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(49807..52380)
                     /gene="mprF"
                     /locus_tag="LP433_000045"
     CDS             complement(49807..52380)
                     /gene="mprF"
                     /locus_tag="LP433_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL2004248.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52521..53327
                     /gene="proC"
                     /locus_tag="LP433_000046"
     CDS             52521..53327
                     /gene="proC"
                     /locus_tag="LP433_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBL2004249.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53406..54962)
                     /gene="rny"
                     /locus_tag="LP433_000047"
     CDS             complement(53406..54962)
                     /gene="rny"
                     /locus_tag="LP433_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBL2004250.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55373..56422)
                     /gene="recA"
                     /locus_tag="LP433_000048"
     CDS             complement(55373..56422)
                     /gene="recA"
                     /locus_tag="LP433_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBL2004251.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56531..57772)
                     /locus_tag="LP433_000049"
     CDS             complement(56531..57772)
                     /locus_tag="LP433_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBL2004252.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(58012..58590)
                     /gene="pgsA"
                     /locus_tag="LP433_000050"
     CDS             complement(58012..58590)
                     /gene="pgsA"
                     /locus_tag="LP433_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBL2004253.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58799..59722)
                     /locus_tag="LP433_000051"
     CDS             complement(58799..59722)
                     /locus_tag="LP433_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004254.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60461..61747)
                     /locus_tag="LP433_000052"
     CDS             complement(60461..61747)
                     /locus_tag="LP433_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL2004255.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61740..63008)
                     /locus_tag="LP433_000053"
     CDS             complement(61740..63008)
                     /locus_tag="LP433_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL2004256.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63260..63721
                     /gene="mscL"
                     /locus_tag="LP433_000054"
     CDS             63260..63721
                     /gene="mscL"
                     /locus_tag="LP433_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBL2004257.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63780..64226)
                     /locus_tag="LP433_000055"
     CDS             complement(63780..64226)
                     /locus_tag="LP433_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2004258.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64319..64564)
                     /locus_tag="LP433_000056"
     CDS             complement(64319..64564)
                     /locus_tag="LP433_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBL2004259.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64679..65257)
                     /locus_tag="LP433_000057"
     CDS             complement(64679..65257)
                     /locus_tag="LP433_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2004260.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65334..65864)
                     /locus_tag="LP433_000058"
     CDS             complement(65334..65864)
                     /locus_tag="LP433_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBL2004261.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65868..66728)
                     /gene="rlmB"
                     /locus_tag="LP433_000059"
     CDS             complement(65868..66728)
                     /gene="rlmB"
                     /locus_tag="LP433_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBL2004262.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66721..67116)
                     /locus_tag="LP433_000060"
     CDS             complement(66721..67116)
                     /locus_tag="LP433_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBL2004263.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67113..68525)
                     /locus_tag="LP433_000061"
     CDS             complement(67113..68525)
                     /locus_tag="LP433_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBL2004264.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68522..69058)
                     /gene="cysE"
                     /locus_tag="LP433_000062"
     CDS             complement(68522..69058)
                     /gene="cysE"
                     /locus_tag="LP433_000062"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBL2004265.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69144..69383)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69380..70840)
                     /locus_tag="LP433_000063"
     CDS             complement(69380..70840)
                     /locus_tag="LP433_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBL2004266.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(71010..72167)
                     /locus_tag="LP433_000064"
     CDS             complement(71010..72167)
                     /locus_tag="LP433_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBL2004267.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72201..73571)
                     /gene="radA"
                     /locus_tag="LP433_000065"
     CDS             complement(72201..73571)
                     /gene="radA"
                     /locus_tag="LP433_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBL2004268.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73634..74161)
                     /locus_tag="LP433_000066"
     CDS             complement(73634..74161)
                     /locus_tag="LP433_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBL2004269.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74391..75197
                     /gene="proB"
                     /locus_tag="LP433_000067"
     CDS             74391..75197
                     /gene="proB"
                     /locus_tag="LP433_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBL2004270.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75194..76441
                     /locus_tag="LP433_000068"
     CDS             75194..76441
                     /locus_tag="LP433_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBL2004271.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76517..76861
                     /locus_tag="LP433_000069"
     CDS             76517..76861
                     /locus_tag="LP433_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004272.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76978..77304)
                     /locus_tag="LP433_000070"
     CDS             complement(76978..77304)
                     /locus_tag="LP433_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004273.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77919..79121)
                     /locus_tag="LP433_000071"
     CDS             complement(77919..79121)
                     /locus_tag="LP433_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2004274.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79238..79753
                     /locus_tag="LP433_000072"
     CDS             79238..79753
                     /locus_tag="LP433_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2004275.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79952..80398)
                     /locus_tag="LP433_000073"
     CDS             complement(79952..80398)
                     /locus_tag="LP433_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL2004276.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80445..81923)
                     /gene="msr(C)"
                     /locus_tag="LP433_000074"
     CDS             complement(80445..81923)
                     /gene="msr(C)"
                     /locus_tag="LP433_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL2004277.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82277..82906)
                     /locus_tag="LP433_000075"
     CDS             complement(82277..82906)
                     /locus_tag="LP433_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL2004278.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82890..83354)
                     /locus_tag="LP433_000076"
     CDS             complement(82890..83354)
                     /locus_tag="LP433_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2004279.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83841..85109)
                     /locus_tag="LP433_000077"
     CDS             complement(83841..85109)
                     /locus_tag="LP433_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL2004280.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85340..86077)
                     /locus_tag="LP433_000078"
     CDS             complement(85340..86077)
                     /locus_tag="LP433_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2004281.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86144..86713)
                     /locus_tag="LP433_000079"
     CDS             complement(86144..86713)
                     /locus_tag="LP433_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL2004282.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86841..87713
                     /locus_tag="LP433_000080"
     CDS             86841..87713
                     /locus_tag="LP433_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2004283.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            88055..88927
                     /locus_tag="LP433_000081"
     CDS             88055..88927
                     /locus_tag="LP433_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2004284.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88924..90882
                     /locus_tag="LP433_000082"
     CDS             88924..90882
                     /locus_tag="LP433_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2004285.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91214..92065)
                     /locus_tag="LP433_000083"
     CDS             complement(91214..92065)
                     /locus_tag="LP433_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2004286.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92188..92655
                     /locus_tag="LP433_000084"
     CDS             92188..92655
                     /locus_tag="LP433_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBL2004287.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92918..93400)
                     /locus_tag="LP433_000085"
     CDS             complement(92918..93400)
                     /locus_tag="LP433_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL2004288.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93500..94363)
                     /locus_tag="LP433_000086"
     CDS             complement(93500..94363)
                     /locus_tag="LP433_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL2004289.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94961..95836
                     /locus_tag="LP433_000087"
     CDS             94961..95836
                     /locus_tag="LP433_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004290.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95981..96133)
                     /locus_tag="LP433_000088"
                     /pseudo
     CDS             complement(95981..96133)
                     /locus_tag="LP433_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96401..97732)
                     /locus_tag="LP433_000089"
     CDS             complement(96401..97732)
                     /locus_tag="LP433_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2004291.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97881..98594)
                     /locus_tag="LP433_000090"
     CDS             complement(97881..98594)
                     /locus_tag="LP433_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2004292.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98769..100193
                     /locus_tag="LP433_000091"
     CDS             98769..100193
                     /locus_tag="LP433_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2004293.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100492..101199
                     /locus_tag="LP433_000092"
     CDS             100492..101199
                     /locus_tag="LP433_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL2004294.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            101186..101509
                     /locus_tag="LP433_000093"
     CDS             101186..101509
                     /locus_tag="LP433_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL2004295.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101598..102635)
                     /locus_tag="LP433_000094"
     CDS             complement(101598..102635)
                     /locus_tag="LP433_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2004296.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(102956..103939)
                     /locus_tag="LP433_000095"
     CDS             complement(102956..103939)
                     /locus_tag="LP433_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBL2004297.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104354..105124)
                     /locus_tag="LP433_000096"
     CDS             complement(104354..105124)
                     /locus_tag="LP433_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004298.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(105117..106052)
                     /locus_tag="LP433_000097"
     CDS             complement(105117..106052)
                     /locus_tag="LP433_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004299.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(106368..108017)
                     /locus_tag="LP433_000098"
     CDS             complement(106368..108017)
                     /locus_tag="LP433_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL2004300.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(108134..110737)
                     /locus_tag="LP433_000099"
     CDS             complement(108134..110737)
                     /locus_tag="LP433_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBL2004301.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(110749..111798)
                     /locus_tag="LP433_000100"
     CDS             complement(110749..111798)
                     /locus_tag="LP433_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBL2004302.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(111824..112138)
                     /locus_tag="LP433_000101"
     CDS             complement(111824..112138)
                     /locus_tag="LP433_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBL2004303.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(112154..112600)
                     /locus_tag="LP433_000102"
     CDS             complement(112154..112600)
                     /locus_tag="LP433_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2004304.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(112601..114523)
                     /locus_tag="LP433_000103"
     CDS             complement(112601..114523)
                     /locus_tag="LP433_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBL2004305.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(114735..115631)
                     /locus_tag="LP433_000104"
     CDS             complement(114735..115631)
                     /locus_tag="LP433_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2004306.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(115624..116304)
                     /locus_tag="LP433_000105"
     CDS             complement(115624..116304)
                     /locus_tag="LP433_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2004307.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(116305..117087)
                     /locus_tag="LP433_000106"
     CDS             complement(116305..117087)
                     /locus_tag="LP433_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004308.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(117080..117997)
                     /locus_tag="LP433_000107"
     CDS             complement(117080..117997)
                     /locus_tag="LP433_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2004309.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(118161..118484)
                     /locus_tag="LP433_000108"
     CDS             complement(118161..118484)
                     /locus_tag="LP433_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004310.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            119272..122499
                     /gene="fss3"
                     /locus_tag="LP433_000109"
     CDS             119272..122499
                     /gene="fss3"
                     /locus_tag="LP433_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL2004311.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            122612..122926
                     /locus_tag="LP433_000110"
     CDS             122612..122926
                     /locus_tag="LP433_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2004312.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            122939..123313
                     /locus_tag="LP433_000111"
     CDS             122939..123313
                     /locus_tag="LP433_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2004313.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            123323..123658
                     /locus_tag="LP433_000112"
     CDS             123323..123658
                     /locus_tag="LP433_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBL2004314.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            123741..125081
                     /locus_tag="LP433_000113"
     CDS             123741..125081
                     /locus_tag="LP433_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL2004315.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            125159..125833
                     /locus_tag="LP433_000114"
     CDS             125159..125833
                     /locus_tag="LP433_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL2004316.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            125826..125990
                     /locus_tag="LP433_000115"
     CDS             125826..125990
                     /locus_tag="LP433_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004317.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            126066..127208
                     /gene="dcm"
                     /locus_tag="LP433_000116"
                     /pseudo
     CDS             126066..127208
                     /gene="dcm"
                     /locus_tag="LP433_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            127198..127488
                     /locus_tag="LP433_000117"
     CDS             127198..127488
                     /locus_tag="LP433_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004318.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            127747..128931
                     /locus_tag="LP433_000118"
     CDS             127747..128931
                     /locus_tag="LP433_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL2004319.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            128928..129065
                     /locus_tag="LP433_000119"
     CDS             128928..129065
                     /locus_tag="LP433_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBL2004320.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            129811..131721
                     /gene="ltrA"
                     /locus_tag="LP433_000120"
     CDS             129811..131721
                     /gene="ltrA"
                     /locus_tag="LP433_000120"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL2004321.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            131825..132049
                     /locus_tag="LP433_000121"
     CDS             131825..132049
                     /locus_tag="LP433_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004322.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            132062..132565
                     /locus_tag="LP433_000122"
     CDS             132062..132565
                     /locus_tag="LP433_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL2004323.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            132625..133014
                     /locus_tag="LP433_000123"
     CDS             132625..133014
                     /locus_tag="LP433_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2004324.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            133001..135448
                     /locus_tag="LP433_000124"
     CDS             133001..135448
                     /locus_tag="LP433_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2004325.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            135453..137576
                     /locus_tag="LP433_000125"
     CDS             135453..137576
                     /locus_tag="LP433_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2004326.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            137573..138577
                     /locus_tag="LP433_000126"
     CDS             137573..138577
                     /locus_tag="LP433_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL2004327.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            138596..139507
                     /locus_tag="LP433_000127"
     CDS             138596..139507
                     /locus_tag="LP433_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2004328.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            139694..139950
                     /locus_tag="LP433_000128"
                     /pseudo
     CDS             139694..139950
                     /locus_tag="LP433_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(140167..140382)
                     /locus_tag="LP433_000129"
     CDS             complement(140167..140382)
                     /locus_tag="LP433_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004329.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(140631..140849)
                     /locus_tag="LP433_000130"
                     /pseudo
     CDS             complement(140631..140849)
                     /locus_tag="LP433_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(141144..142583)
                     /locus_tag="LP433_000131"
     CDS             complement(141144..142583)
                     /locus_tag="LP433_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2004330.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            complement(143171..143803)
                     /locus_tag="LP433_000132"
     CDS             complement(143171..143803)
                     /locus_tag="LP433_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBL2004331.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            complement(144152..145603)
                     /locus_tag="LP433_000133"
     CDS             complement(144152..145603)
                     /locus_tag="LP433_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBL2004332.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
BASE COUNT        42571 a        29960 c        26547 g        46671 t
ORIGIN      
        1 agagtgtttc ccgattcatt tttggctacc gtagcaactt ttatatcata tcagagagac
       61 aagcgattgt caactctttt ttaaaagttt ttttcgattt cgtttttcga aatctttcgg
      121 caactcattt atcataactt atcgtttgtt atttgtcaag aacttttttg aagttttttt
      181 cgatagaatc aagcttcgca agtggttctt ttttaacgac tcagttatct tatcatgtcg
      241 ttagtaacat gtcaataact tttttgttat gtttttgaat aaatattttc ttctgtcttt
      301 tggacaagta ataatatacc aactaaattt agcttggtca acgaattttt tgtatttttt
      361 caagtttttt tcaataaacg attattcata acttttcttt ctttatcgtt cgttttcgtc
      421 ttctttaatg tctagaatag tcggcattag cttttgaact ttcgttatta tttattcctt
      481 tctacacagc aaaagctgcc taaggaattc cttagacagc ttttattcga ttatctcatt
      541 gttgggaata gcaaaacatc ccgaattgat tgtgcatcag ttagcaacat tactaatctg
      601 tcgatcccga tgcctagacc accagttggc ggcataccgt attctaaggc ttccaagaag
      661 tcttcgtcta caccgtgagc ttcgtcattt cctagttcac gttctttttc ttgcgcttcg
      721 aatctttctc tttgatcaat tggatcgttc agttctgtaa aggcattagc aaattcgcgc
      781 cccactatga atagttcgaa tcgatctgtg aatcgaggat cttctggatt tttcttcgct
      841 aaaggcgaaa cttcgactgg atgtccgtat acaaacgtcg gttgtgtcaa tgtttcttca
      901 acaaatgttt caaagaattc attgataaca tgtccgacac ccatagcttc ggttacttct
      961 acattgtgtt tttcggctaa agctaatgct tcttccaatg tcatttcttg ccagaagtct
     1021 acaccagttt gttctttgat tgcatctacc atatggatgc gtttaaagtc actttctaag
     1081 tcgacagctt gtccatcata tgtgattttt gctgttccta gtactttttc agctgcgtta
     1141 cggataatac cttctgtcag attcattaca tcattgaaat cagtatatgc tgtgtatgct
     1201 tctaacatcg taaattctgg attatgtgta gtatcaattc cttcattacg gaaaacgcgg
     1261 ccgatttcat aaactttttc cattccgcca acaattagtc gttttaaatg aagttctagc
     1321 gcaatacgca aatataaatc aatgtccagt gcattatgat gcgtgataaa tgggcgtgcg
     1381 gcagctccac ctgcctcatt gtgcaatact ggtgtttcta cttcaatata gccattgcca
     1441 tctaaatagc gacggatttc gctgataatt tggcttcgtt tcataaatcg gtcaaagctt
     1501 tcgcgattac tgattaaatc caagtagcgt tgtctgtagc gttgttcaat attcgttaag
     1561 ccatggtatt tatctggcag tggacgaagt gcttttgaca aaatcgtgat ttctgaagct
     1621 ttgatagaaa cttcgcctgt gtctgttttc atgatttgtc cagttacacc aaagaaatct
     1681 ccaaggtctg catgtttgaa tacttcatag gcctcatcac ctacttggtc ttttcttaca
     1741 taaatttgaa tttggccttc acgatcttgt agatgcgcaa atccagcttt cccttttcct
     1801 cggcgagtca tcatacgacc agctacacta gcggtcaatc ccatttctgc tagttcttct
     1861 tttgttcttg gatcaaatag ttcatgcaat tcttctgagt tgtgcgtgcg ttcaaatcgt
     1921 tttccaaatg gatcgattcc atcttcacgc aattgttcca ttttttgacg acgtacaagc
     1981 atttgatcat ttaaatcttc tacttgatgt tgttgttcct gtgtcacaaa agttcctcca
     2041 ttctcatgtt aatctctttc ctataatgcc aatgaaacac aaaaaaagca agccgaactt
     2101 ggaatttcgg cttgaaaatt cacgaaaaac ttagaaatca caacgtttgt ttcaatagta
     2161 ctttttccgc tttttctaca aattgatcca gcaggtcatt gatttcttgc tgtttttctg
     2221 tctgattgat tgctactttc actttcgctg ctcgaggaat cccttttaaa taataagccg
     2281 catgtgttct gaattctcta caagctactt tttctccttt gagatctgct aagcgttgta
     2341 aatgaagttt agctgtagca attttttcgg ctggtgttgg ttcaggaatc agttcccctg
     2401 tttcgagata atgctgtgtg cggtgaatca tccatggatt gcccagcgct gcacgaccaa
     2461 tcatcacacc gtctgcaccg acatagtcaa gcatccattt tgcatcttct ggcgttttga
     2521 catccccgtt ccccataaat ggaatcgtca aatgtttttt cacttctttc aatacttccc
     2581 agtccgcttt tccttcatac atctgaaccc gtgtacgtcc atgcatagcg atggcacttg
     2641 ctccagctga ttgtgctgct aatgcatttt ctacagcaaa gacgtgctct tcatcccaac
     2701 caatacgcat cttgattgtt actgggatat ttactgctga agaaacagct tggaccattt
     2761 cgtatacttt ctcaggatct aaaagccatt ttgctcctgc ttctgctttg attactttat
     2821 ttactggaca gcccatattg atatctatta tatcggcagc tgtgttttct tcgacaaatt
     2881 gagcagcttc aactagacta tctttatttc cgccaaatat ctgtaaactt aatggatgtt
     2941 ctgtttcttc aatgtggagc atctctaaag tttttttgtt tctgaaatga ataccttggt
     3001 cactgatcat ttcacatacg actaagcccg caccaaattc tttgacagtg actcgaaatg
     3061 ctgaatttgt tattccagcc atcggtgcaa caacgacacg attagggatt tccacattgc
     3121 caattttcca tgtgtgttcc acttaaatcc ctcctaaggc ttctttcttc aatccatcta
     3181 attcttcttc gctatacttg tatttgttat tacagaaaga acaaaccgct tctgcaccgt
     3241 gatcttcgtc tatcattgct tggatttctt ctgcacctaa cgcgataatt gcttctgcaa
     3301 atttttcttt tgaacagtca catttgaatt gaacaggcat tttttccaaa atgttcaatt
     3361 cttctgtacc aagcaatcct ttcaatattt cttctggtgt ctgtccttca tctaagaggg
     3421 tagagattct tggtgtcgtt tttaattgtt cttcgatctt gctgattgtt tcttcatcgg
     3481 cacctggcat gatttggatc atgaatcctc ccgccgtctt gatgctgtcg tcagtattga
     3541 ccaatacact cagtccaaca gctgaaggga tttgttctga gatagcaaga tagtaagtaa
     3601 aatcttcagc gatttctcca gaaacaatcg gcgtttgccc agaaaaaggt tcttttaatc
     3661 ctaagtcttt tgtgacagta aacattcctt gtgttccaac tgctccccgc acatcgattt
     3721 taccttcact atttagagga agactgagat gcggattttt gatgtaacct ttcacatctc
     3781 cctttccatt tgcatctact acaattcctg ttgctggacc atcgccttgg attcgaacag
     3841 ttagtttgtc ttctcctttg agcgtcgcac caagtagcag actaccgacc aatgtccgtc
     3901 ccaaagcagc tgaggaggtg tgccaagtat catgacgtct ttgtgcctcc gctacggtat
     3961 ttgttgcttg aacggcgtat gctcggacga atccgtcgtg agcaagtgcc ttaaccaaat
     4021 aatctttcat ttgttatgta ctcctttttc cgtttttaaa ctcatagtga atcatactag
     4081 caactactgc ttttttcaac tttggaatgc ttcttttaaa aataattcag aatcatctag
     4141 aaaacaggac atcaccctat ttacaactta aataaagaaa tctcccgaaa accggttttt
     4201 gttccggttt tcgggagtca tatcagatca attgacctat atttttttat ttgtattgat
     4261 cgtctgaatg attatcttct gattgttgag aatctgaatc atgttctgct ttattttcct
     4321 cattcagttc atgttttgct tcttcaaaat cacgtttttc ttccgcttgt ttttcagcgt
     4381 ctttttcttc caaagcacgt tttgcttctt caaaagtttt cgcttctttt tcgcttggat
     4441 aatcatttga ctcagtacct tcaggcatca caccgtgttc aaacaatgac ttgattgctt
     4501 tggcatccaa tgtttcgaat tccaaaagtt tttcagcaat cagtttatgc tgtgcacgat
     4561 gagcttcgat gatttctcga gctttatcat gagcttccat caagattttt cgtacttctt
     4621 gatcaatctc gaaagcgact tgttccgagt aagcttttgt ttgaccatag tcgcggccaa
     4681 caaacacttg atggtttcct tcatattgaa caggacctaa acgatcactc attccatatt
     4741 ctgttaccat gcttcgtgct agagctgtcg cttgctcaaa gtcattggaa gcaccagttg
     4801 attggacatt gaagatgatt tcttcagctg tacgtccacc aagtaagcct acgatttgtt
     4861 caaacatatc ttctttcgtc atcaagaact gatcttcttt tggtaaagcg atcatatatc
     4921 cgccggcgcg tccgcgaggg atgatcgtta ctttgtggac gacccgagcg cgactcaata
     4981 ctaatccgac aatcgtatga ccagcttcgt gataagcaac catttcgcgt tcttttttgc
     5041 tgattacgcg atctttttta gctggacctg caatcacgcg atcttccgct tcatcgatat
     5101 cagaagcatc gattttcttt ttatttcttc tagcagctac taacgctgct tcattcaaga
     5161 cattttctaa atctgctccg gcaaaacctg gtgtctgttg agccacaact ttcaagtcaa
     5221 cgtcatctgc catcggttta ttccgtgcat ggactcgcaa gattgcttca cgacctttta
     5281 catctggacg tccaactaaa atctggcggt caaaacggcc tggacgtagt aacgctgggt
     5341 ctagtacatc agaacggttg gttgcagcaa tgacgattac tccttcattt ccgtcgaagc
     5401 catccatttc tacaagcaat tggttcaatg tttgttcgcg ttcatcatgt ccgccgccca
     5461 taccggcacc acgttgacga cctaccgcat caatttcatc aatgaaaatg atagctggtg
     5521 cgtttttctt cgctgtttca aacaaatcac gaacacgact tgctccaaca ccgacaaaca
     5581 tttctacgaa atcagaaccc gagatcgagt aaaacggtac tccagcttct ccggcaacag
     5641 cttttgctaa taaggtttta cctgttcctg gaggtccttc taaaagtaca cctgccggga
     5701 tacgggcacc taattcaaca aatcggcgag gatctttcag aaattcaaca acttcaacta
     5761 gttcttgttt ttcttcttcc gcacccgcta catcagaaaa acgtacgcga ttagcttttt
     5821 tgtctgcttc tttggctttt gatttaccaa agttcatgac acggccgcca ccgccaccgc
     5881 cgccgccttg ttgtcccatc atcatgtaaa agaaaaagat gatgattacg attggcaaga
     5941 agctaagcaa tagggaaacc catataccgc tgcttgattc ttcttttact gttgtagcaa
     6001 ctttgttttc ttttgccagt tctgttactt ggctcaatgt tgtatcattt ggcaaaatga
     6061 ttgttgtgaa atgggtagta gtcgtatctg ttgaacctaa gatagctaac ccaccgctgt
     6121 tagcgacggt ctgctgttct ttgtattcac cagtgatctt atatacacca tttgcaggct
     6181 gcacttcaaa ttctttgatc ttgcctgctt gtagttgttc tgtgaatttt gagtactcga
     6241 tatctgacga tcgctggccg ttattaccaa aaatgaaata aacgaccatt accatcgcta
     6301 agattacgag gacataatac aaggcatttt tcatcatgcc gttgttcttt ttgttcatag
     6361 ttgccctccc taagcgtcaa tttaatttaa cagtttttta tcaatcctga ccattctatt
     6421 gtaccataat ttaattgaga tacagcatta atttgattga taaacactag gtttcaatac
     6481 accgatgtac ggaaggttac gatatgcttc tgcataatcc aagccataac cgaccacaaa
     6541 ttcatttggt acgttgaagc caacataatc tgcttcgata tttactactc ttccttcagg
     6601 tttgtcaagt agtgtaacaa ttttgactga ttttgctttg cggtatttga aaagatccac
     6661 taaataagca agtgttcttc cgctgtcaat gatatcttca acgatcaaca gatcgcgacc
     6721 ttctacattc gtatctaagt ctttgacgat ttttacttcc cctgacgaga ctgttgcatt
     6781 cccgtagctt gaaacatcca tgaaatccaa ttccaaatac gtatcgatag aacgaacgat
     6841 atctgccatg aatggtaccg ctccttttaa gacacctact actaggggat tggtgttttg
     6901 gtaaatttct gttaactctt tgcctagttc tttgcaacga acttgtatct cttcttgtga
     6961 gatcaaaatt ctctcaatat ccttttccaa catcaggttc tccttccaat tgcttctttt
     7021 tgatatttgt aaagaagtat gtagtgtatt ttatcagttt cttcacgaat actcaaatat
     7081 gaaaaggcaa aaggtatcaa gctatatata tttcttttgg catctgtaat gatccaagca
     7141 tgctgccttt gtgaattagg tactttctga tcgataaaat atctagatac tttttttgtg
     7201 agattctctg ttaatttaat gcggtctcct gcttttcttt tttcgacata cagttgcaca
     7261 tcagcaggaa tccaaatgtc atgagaaaat agagaccatg aatctgttgc tttgatgtcc
     7321 cctgcatttt caggtttgac cagaccaatc cattctgttt cattcaaata tattccttgt
     7381 tctggaatca gcaacaagcg ctggtcttct gtctggctag ttgcttgttt ttctttttta
     7441 gagagtacaa caaaatgata ctctcttttc agtatccaat tattgccaat actgagttgc
     7501 cattggcttt ttttctgttg ccactggtct aaaatcgact ccatttgttg ttctttcaaa
     7561 ataattcctg tttttgagaa tgctttgtcg aaaaaggagt aaaaaaaata gtatcgttca
     7621 gcatctgtca tttcttcaat catttctgca gaaaatcgaa attgttcctc ccactgttcg
     7681 acttcctttt cgatcaactg tcccatatat ttttgaatga cttggtctgc ccattggatc
     7741 tgttgcgaaa attgctggaa atgtctcaac gcctgtgtat tttcttgttt caattgagga
     7801 actaccaaat gacgaagccg atttctctgg atatctaaca attggtttgt ctgatcctca
     7861 aagtaaacaa gctgcgattc cgctgcataa gtatataggt cttctttgct aaaactcagc
     7921 aacggacgaa tcagtctgcc cgtagcaaat ggttgtactt ctttgattcc agaaaaagta
     7981 tttaactgtc ccccacgaac gattttcatt aacaccgtct cgatttgatc atctccgtga
     8041 tgagcagtca tcaacgtgtc atattgtcct tcttccatca cgcgagtgaa ttcttgataa
     8101 cgaaagttac gagcttctgt ttctatggcg gatttggctg gatcttccca aatacttaca
     8161 tataaaggga gattcttctc ttcacaatat gagcgaagat aggcagcttc ttctgctgat
     8221 tcttctctta attggtgatt gatgtggacg atacctaaag aaaaaccgat ttggcgttgc
     8281 acttgtaaaa gtaaatggag caaaaccatc gaatcaacac cacctgatac cgctgctaaa
     8341 attctcgatc cttgttgcca gaatccttgt tcattcccgt gccgaataaa tgactgctgt
     8401 aatagcggtg cttttttccc gcctttttca acgttcatcc tttccacacc ctttcttcct
     8461 aaaaaaaaga gagcgggaaa acgtctaaaa cgacaattaa cctgccctct gttgatacta
     8521 tgacccaaat agtcgcacta tcattatttg cggcttttta gctgcgacgt ccgccacggc
     8581 caccgcgctt tccttctgtg tttcgcttca atgaagataa gcggtcatcg ctatctttca
     8641 aaaatgaact catcaatgaa tcgaagtctt ctttttgagc tgaaggttga ctgcgagaaa
     8701 aagatttttt ctgtgctgga cgatttcggt tgtcacgggg atctttttgt tgatattttt
     8761 taggacggct ttcttctcca gattcagcag gttgttcctg cgctttccgg atagatagtc
     8821 cgatttttcc atcatcattt actgaaataa ctttaactgt tacttcatct cctacactta
     8881 aaacatcatg gatgtctttt acatagccat ttgacacttc gctaatatga actagacccg
     8941 tttttccagc acctagatca ataaacgcac caaaatttgt gattcctgat acttttcctt
     9001 gcagttttgc tcctacctcg attgacataa aaaaaatgtt cctcctaatt atttcccttt
     9061 tttatattcc tgcttatttt gcagttgtag aactagttga ttgatctgtt tcatttgtcg
     9121 agctgtctgt atttgattct aatataggat aaactttttc accgtctttt gagtaaaaga
     9181 atttgcttct ggcaagttta gctacatact catcatcttt cagcaatgaa acatcttggt
     9241 gcagctgatc aacgtctgcg ttgacttctt tcatttcagt atttgcttcg actctcaatt
     9301 cgttcaattg atgcatcctt tgcatgtcat ggaaaatctg cacacctatt atcgcgaaaa
     9361 tgaccaaagc accaacaaaa attgcagcca gtctgcgtct tcgaaaaatc agttgacgtt
     9421 gttgttgctg aaattcagca tactttttct ttgcatattc cgtatctagc gcagcgattt
     9481 tattgctttt tttcgtcact tggattcgct ccaatctttt tgattgtctt tttcattata
     9541 ccaatatcgt gaaagcttgt ctaatctatt tctctagtgt ttctgtgcga ttttcagaaa
     9601 taatttcgta cattttttgt gcatcttctt ttttggttga ttcatgtaat tccgtaattt
     9661 tcacttccaa cgttttgttg ccaaactgga ctttcaaaat atcgcctact ttgacatcac
     9721 tggaagattt cgccaattta ccgttgattt gaattcttcc tttatcagct acttcttttg
     9781 ctactgatcg tcttttgatg attcgggaaa tttttaaaaa tttatctaat cgcatatctt
     9841 attcctcact ttttaatttt tttatttaat cgcaggattt tcttaccaaa aggcaacatt
     9901 agccattctc gtactgtaaa cagacgaaga cgaatcactg cataaatgaa cacagaagcc
     9961 ccgatcccaa ctcctatcac gctgacaaaa aaagcagtgg aacgatgagt tacaggacca
    10021 aatactatat tcaatacacc ataatacagc agcagtacta ctgtcataca aagaaggctg
    10081 aacatcaact tccgtccaaa atgccgttct ttccaaaaag catttagctc ttttgtttca
    10141 attcgaacaa aataccaaag cgtcacacct aatcctaaaa gggtagacag gcttgcacct
    10201 gctgttccta ataaaccggt cagaaaagaa gtagtcaatc cttttaccaa tagtccccat
    10261 cctgcgcctt ttaaagaagg gcgaaacgag ttcttgcttt gagcaatact ttgataagct
    10321 tggatgactg cagtgaaagc aatggaaaaa acaaataata caagcgctgc atttcccgca
    10381 taatctttaa acaacgcata attgatataa gggagcagca aggctaatcc caaagacgca
    10441 gctaatgcta aagcggtcgt caatctaaga tagattttgg ctgtctgtaa aaactgacga
    10501 tagatccggt tggtcaaatg acgagtcaac gcaggcagga atgtcgcact taatgcagtg
    10561 gcaatcacta aacctaattg tactaaaggc tgacctcgat catagacccc ttttgctatc
    10621 ttcgcaccgt attctgacag tccgtaaact tccaaagcat tttttacaaa gaaagagtcg
    10681 atcagctgga aaaagataag caatccacta taaatcgaaa ccagtccgcc ttctaccaga
    10741 aaacgccgga tcaagggctt tgacggctgt ttgaacaatg gaaaccgtcg gaagcttaac
    10801 gctcctccat gaatcttttg ttcatagtag tgaaggatcc catatgcgca taaaccgcca
    10861 aaaacagctc cactcattgc tgccgtccct gtttggtaca ccgtccatcc aagctttcta
    10921 aaagcaaacg cactacagac aatcacaaaa acacgaacga actgctcaac tacttgagaa
    10981 acagcagttg gttccatcaa gaatcttcct tggaaattcc ctcgataaaa agatagacca
    11041 ggcatcagca aaaaggtaaa ggaaactact tggatcagcg gtttcaattg tatgtctccc
    11101 atcatccaag caatccagct gctaaatgca aagacaaaca accacaaaaa gacacctgtc
    11161 caaaatacta agggataaag attttgcaaa gcttgctttc gctcgaaagg attctttctt
    11221 tctgcaacgt actttgatat gaactgcgga agaccggata aagctaaagt cattgctatc
    11281 ccataaattg gataaacttg ctgataaaca taaaaacctt cgtcgccgac taagttttgg
    11341 aggggaattc ggtaaagggc acttaatact tttgctatga aagaagcaat cgtcaataca
    11401 aatgctcctt gcatgacgcg ccgcatttct ttatgatcca aatcattgct ccttcctacg
    11461 ctgacagata tttttgctca cgcaacgctt tgacaaactt ttggatttcc tgaagccata
    11521 ctgcttcttc catttggttg gggatcgtca agcgtatcac catctgttct ttttcaacgc
    11581 ctagactggc ttttagtttt gtcgctgtca gtgcttcgaa taactgttcc acactatagc
    11641 gttttgttcc aactttactt agagtaaaga ctatatgcgc ctcctgtttc cttatcgttt
    11701 ctaggagcgc tcgatcgcca tccattttga tctgcccaat tgtcaagaga tgtgctactt
    11761 cttctggata ttctccaaaa cggtcgagca gatcatcttc tagttcatct agcatttctt
    11821 gcgaatcaag ttcacgaatt cgtttataga tctcgatttt ctgccgttga tctgccacgt
    11881 atgtttcagg tagatacgca tcgacaccga ggtcgatctc aacagtggtc ttctccactt
    11941 gactattctt tccttgttta cgagaaacag cttcgcttag catttgagaa tacatatcga
    12001 aaccgactgc atcaataaat ccatgctgct gagcacctaa gagattacct gcaccgcgaa
    12061 tggaaagatc ccgcatcgca atcttgaatc cagatcccag ttctgtaaaa tctttgattg
    12121 cctgaagacg tttttcactg acttcgttaa ggatcttctg ctgctcatac ataaagtaag
    12181 catatgcgac acggctgctt cttcctaccc gccctcgcaa ttggtataac gtggataatc
    12241 ccatataatc agcgttctca acgaacaacg tatttgcgtt cgggatatct actcctgttt
    12301 caatgatggt tgtagtgaca agaacatcat attgaccttc aataaattca aaaagcgtat
    12361 tttctaattg cgcctctgtc atttgcccat gagcataacc gatccgtgct tccggaacga
    12421 gttcttggat ttcttctact ttttgttcga tcgtttctac ccgattatat aaatagaata
    12481 cttgtccacc tcgtcccatt tctcgatgga ttgcttcgcg aatagcccca ggattttttt
    12541 ccataacata cgtttggatc ggataacgat tcgcaggcgg tgtttcgatt actgaaagat
    12601 cccgcacgcc taacatcgac atatgcaaag ttctcggaat cggtgttgca gtcagagtca
    12661 aaacatccac ttgtgcacgt aactgtttca atcgttcctt atgttttaca ccaaaacgtt
    12721 gttcttcgtc aatgatcagt agacccaaat cgctaaattc aatatctttt gacaaaattc
    12781 ggtgggttcc tacaacaata tcaacttgac ctgtacgcag ttgttcgatg gtttcttttt
    12841 gttgctttct tgttctgaaa cgacttaata gcccgatatt tacggggaaa ccttcaaatc
    12901 tttccagcat cgtttcatag tgctgctgtg ccaagatcgt tgttggaact aaaaaggcta
    12961 cttgtttgct ttcctttatc gctttaaagg ccgctcgaag cgctacttct gttttcccat
    13021 aaccaacatc acctacgagt agtcgatcca ttggtttttc tttttccata tcccgtttga
    13081 tctccgctgc acttctcaac tggtcatcag tttcagagta ggggaaggca ttttcgaatt
    13141 ctttttggta ggcgtcatca ggtccaaaag catatccttt ttctgactct cttgcggcat
    13201 ataatttgat tagatcgtca gcgatatcct cgatttttga agagactttt cgcttggttt
    13261 tcgtccattc acttccgcct agcttattga tgcgaggcgc tttggcttca gaggcgacat
    13321 atttttggat cagattcagt tgagtaacag gaataaacag tttgtcgtcg ttttgataca
    13381 aaatagtcat atagtcttgg tgaacgccat ctacttctag cgtttccatc ccaatgtatt
    13441 tcccgatacc atgattggca tggacaacgt aatctcctgc ttttaactca ttatagcttt
    13501 tcaatcgctc tgcgtttgtt actgtttgac gtctcgtttg ttttttcgtc gttttttgga
    13561 aaatttcttt ttctgtgata gctactattt tttcttgagg aagttcaaaa ccagcctgca
    13621 aagctccttc aactaattgt acctgtcctc tgatcaatgc atttttttct gtttctacta
    13681 ctaatatgtc ttcatctcga agcatttgtt ctgctttgcg tattctgtcc tttgtcggaa
    13741 taaagatcac aacagtctgt ttttgcttgc gccaacggtc catttctgtt ttcagcaatg
    13801 gcatttgtcc gaagaactgt tgcatcgtcc gatattgaaa attatggatt gcttggaaac
    13861 gaagatttcc catccctttt tggaagagtg agaaaaaggt tgtggtgaac ttttccttct
    13921 gcacgatttt ttgtatatct gctgaaaatg tctgctcaga aaacacccgc aattcgctga
    13981 ttttttgagt ctgccattct gccgcttccc tttcgatttc ccgatttgtt tccatgattc
    14041 gctgataatc atcaacgact agtaaactat ttgaagggaa ataatccaag atcgtcacag
    14101 attcttggta aagaagatct gagtagaatt ttgcttcttc tgtcgggaca cctgcttgcc
    14161 agcttgaagt cagctgaccg aagtaatctt gcaaaaactc gcggtctgct tcttctgtgg
    14221 tcgcagcaag ccgtttttct agcatttttt gcatttgctc tattccatgt tctagatcct
    14281 ctggtccgta gacttgttca ctcgttgggg aaacccagat ttcttccgtt ttttcgattg
    14341 agcgttgtgt ttctgcttca aaataccgca tagaatctat ctctacatca aatagttcta
    14401 cacgaacagg ataggttgtc gttaacgggt aaatatcgat aatgcttcct cgaatactga
    14461 attctcccgg ttttgcgacc atctcttctc gtacatagcc catcaaagtc aattggcgag
    14521 gaagattttc cacgtctatc tcatcaccaa tatgccaatt caattgcgcc tgtagccaag
    14581 ttttcttatt cggcagtcgt ttgtgcaaag atgcgactgg caacaaatag atacctgctt
    14641 ttttttcttg aagtgcgtta agcgttgcaa ctctctcgcc tcgcgcttct ggagaagaaa
    14701 aggccatttc agcagaaagc acttcatcca ctggaaataa atggatctga tcttgcggaa
    14761 tcacatgttg cagatcttct gctaactgat tcgcataata caaatttggc atcagaataa
    14821 tcatgttttt atttgttttc ttaaacgctc gagcaaatag aagtgttttc gctgagcccg
    14881 ctaatcctgt gattagttgt ctaggcattt tttcttctaa attgctgacc cattctttta
    14941 cttgcggatc ttttccgact aattgaataa tatccattcc ttttcctcct tcctcaattg
    15001 aatcgattca tcgcatccac gaacgaatgc ccttctatga gatattcgac tgctttaaca
    15061 gattgacaca tgctttcttc tatcaaaggc tgattttctt tgctgaaagg actaagcaca
    15121 tgctggacta ctgttttttt cccttctggc ctgccgattc ccaccttgat tcgatcaaag
    15181 acattcgtat tcaaatggga aataatactt ttgataccgt tatgcccgcc ggcacttccc
    15241 ttttgacgga gccggatttt tcccactgcc agatccaaat catcgtagat tacgactaat
    15301 tcctctggat aaatcccaaa ataagtcatt agtgggccga ctgcacgacc agattcattc
    15361 atgaatgttt gtggtttgac taaaaggatc ttttctccat tatgaaaaaa ttcggcaact
    15421 tctgcttcga acggattttt tttgaaagta gcttgatgct cgcgtgcaat tttatccacg
    15481 accataaagc cgatattgtg ttttgtatat tggtatttgg tacctgggtt tcctaacccg
    15541 acgatcattt tcatttttgt tttccaccta attctaaaaa gcagcacaaa aggctggact
    15601 gctaattagc ggtccagtcc atcgagcttt tttctttttt acacttgtca atgcatagta
    15661 taacacaaaa caaggcgttt cggctaaaag agaatcgtta ataaatgata aagaaattaa
    15721 aaatttcttc aaagtttaat gaaataattg atatataaaa atagtgaaat aacgcacatg
    15781 taagctttta catataatac aaccttgtta tctgttatat tttatagcca aatagcgtga
    15841 catggggctt gagaaatgtt agcataagca tgggaaaaaa caaatcaatg gaaggattga
    15901 tactaaatga ctgcagctgc agaaaaaaaa gatcatcaaa aagttattct tgttggagac
    15961 ggcgccgtag gttctagcta tgcctttgct ctagttactc aaaatatcgc tcaagaagta
    16021 ggtattgtgg atatcaatac tgctaaaact gaaggagacg caattgactt gtctcacgct
    16081 ttggcattta cttcacctaa aaaaatctat tctgctactt acgcagacgc acatgatgct
    16141 gacttagttg ttattacagc tggcgcacca caaaaaccag gtgaaactcg tttagactta
    16201 gtaaacaaaa acctaaaaat caaccgcgat gttgtcacac aaatcgttga atcaggattt
    16261 aacggtatct ttttagttgc cgctaaccca gtagatattt tgacttactc aacttggaaa
    16321 ttctcaggtt tccctaaaga acgcgtaatc ggttcaggta cctctcttga ctcagctcgt
    16381 ttccgtcaag cacttgcgga attagttgac gttgatgcac gtaacgtcca tgcttacatc
    16441 ttaggtgaac acggagattc agaattccca gtttggtcac atgcaaatgt tgccggcttg
    16501 caaatctatg aatgggtaaa aaacaaccca gaaatcgatg aagaagctat ggttaaccta
    16561 ttctttggcg tacgtgacgc tgcttacaca attatcgaga aaaaaggcgc tactttctat
    16621 ggtatcgcag tagcattagc acgtatcact cgtgccatct tagatgatga aaatgctgtt
    16681 cttcctttat cagtattcat gaatggcgaa tatggattga acgacatcta cattggtgca
    16741 cctgctgtta tcaaccgtca aggtatccaa aaagtaatcg aaattccttt aagtgacagc
    16801 gagcaagacc gtatggctgc ttctgctaag caattaaaag aaattctaga tgaagctttt
    16861 gctaaactag acgctgaata atctttgaac atgacggaaa acatctattc ggtgttttcc
    16921 gtttttttat tttatcaccc ttatggtttc taaatttttt cataaagtag agataacctt
    16981 cgtcttttcc tctaaattat gctatcatga gaccgttcca ccctaaactt ttacttaagg
    17041 agttgtcgat atgacaagat cttcgcatcg aaaaaaatcg aaacatgttg ctttgctttc
    17101 agttcttggt gttctcttag tgctgatcag cttttatacc tatcgcagta catactacac
    17161 aaagcatttt ttgccgaata cagaaataaa tggaataaat gtcagcaatc taacagtcga
    17221 aaaagcaaat gaaaaattaa aagaagctta ttctgataaa aaactggcta ttaaagaaga
    17281 tggaaaagtc tggcaggaag taccaaaatc cgagctcggc tacaaagatg atttcacttc
    17341 ggagctttct ccgatcctaa atgaacaaaa cggatggact tggggaatga cttatgtctc
    17401 agcggcagaa aaacaagaaa tagatcctgt cagtcaaaac caccaaaaac tagacactac
    17461 cgttcagaca ttgacaacta agctgactga tttgaacaaa gaccggacac ctactactga
    17521 tgcaacgatc gaaaaagcag gtgactcttt cgttatcaag cctgaagtca atggaaatac
    17581 gatcgacgtc gatgctgcgg tcaaacaatt aaaaagtgcg gtaaactctg gtaaagatac
    17641 aattgaattg actgaattca aagaaaaacc aaaagtaaca tctgaagaca gctcactgaa
    17701 agaacaactc gcatccatga atgctatcgc aaatgtaaaa gctacttaca gtataaacgg
    17761 tgagactttc cagatcccat caagtgatat tatgagttgg ctgacctaca atgatggaaa
    17821 agtcgattta gatacagaac aagtacgtca atatgtaaca gatttaggca caaagtataa
    17881 cacaagtacg aatgacacaa aatttaaaag tacaaaaaga ggagaagtta cggtcccagt
    17941 tggcacttac agttggacga tccaaacaga cagtgagaca gaagcattga aaaaagcgat
    18001 tctggcaggc caagatttta ctcgttcacc cattgtgcaa ggtggcacaa ccgctgatca
    18061 tccattgatc gaagatacgt atatcgaagt tgatctggag aaccagcata tgtggtatta
    18121 caaagacgga aaagtggccc ttgaaacaga tatcgtttcc ggaaagccaa ctacacctac
    18181 acctgctgga gtcttctatg tttggaataa agaagaagat gcaactttaa aaggaacaaa
    18241 tgacgatgga acaccttacg agagtccggt aaactactgg atgccgattg actggacagg
    18301 tgttggtatc cacgattcag actggcaacc tgaatacggt ggagacttat ggaaaacccg
    18361 cggttcacac ggctgcatca acaccccacc aagtgtaatg aaggaattat tcgggatggt
    18421 cgaaaaagga acgcctgtat tggtcttcta acaaaaataa tatataaaaa gaaagcaccc
    18481 gtacgattgg tacaggtgct ttctttttat tatctaacaa tgtgctactt acatttcagc
    18541 agcagtaaag acttctgaaa catcatcatc gtcttctagc ttatctacta gacgttccaa
    18601 ttgctctttt tgttcctcat ttaaatcaat cgtcgtttgt ggaatcatcg tcaattctgc
    18661 ttgcgccaaa gtgaactctt tttccaactc atctcgtaca gcagcaaaat cttctggtgc
    18721 agtataaatc tcgaatactt caggagaagt ttgcagatct tctgcccccg cctctaatac
    18781 atcctcaaac atcgtctctt catcaacagt caacccatcg cgttcaatag cgatatatcc
    18841 tttgcggtca aacaagtaac tgactgaacc cgtttctccc agtgatccac cgtttcgagt
    18901 aaaagctact cggacatttg tcgctgtccg attacggtta tctgtcaatg catggactaa
    18961 gattcctact ccacccggac catatccttc atacgtgatt tcatcgtaat tcgtttcatc
    19021 tacggcactc gtagcctttt taatcgcccg ttccacattg tcgttaggca tatttgcagc
    19081 ttttgctttg tccacaacaa gccgcaaagc tggattcata gatggatcag gaccgcctgc
    19141 tttagctgcc atataaattt cacgagaaag tttctgaaag actttccctc gttttgcatc
    19201 ttgggcattt tttcttcctt ggatattatg ccatttacta tgtcctgaca tgatttttcc
    19261 tcccttgttc ttttgagaat acacttctat tctagtacta tttcacaaaa aaacaaagcc
    19321 acagccaatc tataaacgct tcttgaatgc cgcaaaaagc acacataata tcacagcagt
    19381 cagagcaccg atcgaatcca acatgacatc ttggaacata ggtgttcgtc caccggtcat
    19441 catctgatgg aattcgtcca aacctgcgta ccctgttgct gaaagccaag caaggatcgc
    19501 tgtcagccac caaattttta gcttggggaa aacacctaaa aacaagctgc ctcccaaaat
    19561 aaaataggta ccgaaatgtg cgcccttcct taaaaagaac tctaaaaatt tggcgtagcc
    19621 cagatggttg atactcacca tacttccacc ataattaaaa cgtatacccg ctaatgtgtc
    19681 tttaaatggc tgattaggca gccagctttc taatcgcgaa acttgtgatt gctgtccgta
    19741 agtttgagaa gaactgtaaa ataagattat aacgactatc agtgcgatta ctaaataaat
    19801 atttccgttt ttcatttgtt tttttgaaga attcataagt cacctctgta ttttatctta
    19861 gacttttttt gaagaaacaa caatcatttt catagagact tcttccataa aaaagtgcta
    19921 tacttaattt tgtattacaa tatgaaggga gttttttcat gagttattca ttaaattgga
    19981 atctagattc tattttttcc ggaggcagtc attctgatgc tttgaaccaa cggatgaagc
    20041 aattggaaga ccaaatgaac gagtattatc accgcgtaac aaaatggtca cctagttctg
    20101 acaatgcaga gcagttaaac gctattcttc aattgcaaga aacgattacg aatggtttta
    20161 cccaatgcag cagctatatt actgcattgc tttctgccaa tgtcaatgat tcagatgcaa
    20221 aggtcttatc aggcaagctt tacgcaatgc tgcctcgtct gcaatcagcc gaaactgtat
    20281 tgtcaaagaa atttgcagaa atatctgaca atgattggaa tcagatgctt tctcaatctt
    20341 cgtttgaaac aattgctttt cgtttaaacg agattcgtcg tgatggctca caattattat
    20401 cagaagctga agaaaacatt ataaatacgc tttctttaga tggtctaaat gcttggagca
    20461 gtcattatga tacgattgta gccagcattt cgattccctt cgaacaagat ggacaagtag
    20521 tcgaattatc tgctggacaa gccttcaata agatgatggg cgatccagat ccaaaagtca
    20581 gagaaacact tttcgcagca tgggaagaag cctggaaaga aaaggcaccc ctcttcacgg
    20641 atactttgaa tcatttagat ggttttagac tttctgacta tgaacttcat ggtgtcacag
    20701 attttctaca aaaaccatta gagtacaatc ggttgaagaa agaaacattg tctgtcatgt
    20761 gggatacaat ccagaaaaac aaacaacccc ttgttaatta cttgactaga aaagctaatc
    20821 ttttcggtaa agaaaaaatg gaatggcaag atcaagatgc acctattatt ttaggcgatt
    20881 tgaaagaaaa aacctttagt tttgacgaag cagcagcatt tattatcgaa aactttaaca
    20941 aattcagtcc aaaaatggct aaatttgccc aatctgcttt tgaaaagagc tggatcgaag
    21001 cagaagatcg tcctgggaaa cgtcctggtg gttattgtac tgagttacca gaaacaaaag
    21061 aatcaaggat ctttatgacc tacagtaatt ctgttaatga ggttgcgaca cttgctcatg
    21121 aactaggaca tgctttccat agcagcacga tgtgggattt accttcttta aatcgcgaat
    21181 atgccatgaa tgtcgcagaa acagcaagta cattcgcaga actgatcgta gccgatgcta
    21241 cattaaaagt cgcaaaaaca aaagaagaaa aaatcaattt gctagataca aaactgcaaa
    21301 atgctttagc tatgttcatg aatatccatt cccgattcat ttttgaaaat cgattctatg
    21361 aagcacggca agaaggatta gtctcagaag ataagatcac agagatgatg gttgaggcgc
    21421 aaaaagaagg ctatcaagga gctttagcta cttaccatcc atatttctgg gctgcaaaat
    21481 tgcatttctt tattgatgac gtaccgtttt ataacttccc atacacattt ggctacctct
    21541 ttagtttggg catctatgct tacgccaacc aaaagggagc aaattttgaa gaagaatata
    21601 tccatttact acgcgatact gcctcaatga cgacggaaga tcttgcgaag aaacatttga
    21661 atgtcgatct tacccaacca gatttttggc aagcaggtat cgacatggtg actgaagata
    21721 tccaaacgtt catggaattg acagaagaat ttatctgatt tctattttat cacaataaaa
    21781 aaagagttag tccagaatgg gctaactctt tttgattaat cattcttaca tgctgacagc
    21841 aaagtcaggg gcaaaccatt gaactgaacc aacttttacg ctttcgcctg gttgaggagc
    21901 atggatatat tgtcctccgc ctaaagcaat cgctacgtgg taagttccgc cttgtgaccc
    21961 ccagaataac aagtctccag cttttgcttg agaaactgaa atttttgttc cagctgattc
    22021 ttgaggaact gtccaaccac cgatgtcacg accagttact tgcatgtaaa catagcgtgt
    22081 gaaccctgag cagtcaaagc cacttggatc tttaccgccc caaacatatg gagtaccaat
    22141 atatttgtaa gcttctgcta cgattgctgc accattcaca cttccagaag gagctggagc
    22201 aggtgttaca ggttttggtt gttcaggtgt tggtgttggc gttggagccg gagtactact
    22261 tcctgtgccg tttcctgtat caacactttg atctgttgat ggtgttgtag gcgcaggtgt
    22321 tgttgattct tctgttgttg aagattcagg cactgttgtt gattcttctg ttgctgaaga
    22381 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcgctgttg ttgattcttc
    22441 tgttgctgaa gattcaggcg ctgttgattc ttctgttgaa gattcaggtg ttgttgattc
    22501 ttctgttgct gaagattgtg tagctgatga tgattcttca gtcattgaag attgtgtagc
    22561 tgatgattct tctgttgctg agctttgtgc agtagatgaa gcttgagtag cttgtgcttc
    22621 agcctctgct tgttcgcgtg cttctttttc agctttttct tgtgcagctt gttgacgagc
    22681 ttgttctgct agacgttgtt gttcacgaat acgagcttgc tctgcttcag cttctgcttt
    22741 ttgacggttc aagtcagctt tcttgtcttc agcagttgct tgttcagcag ctaatgaagt
    22801 tttcagtacg ttcaaatcag cttgtttaga taaaagatcg cctttttgag attccaaagc
    22861 agcttggttt tcagctaatt cttttagttt agcatcgttt tcagcttttt tgtcttctac
    22921 agctttttta tcttgttttt gttgttccat caagtcgttg tttgctttta ccatcgttgt
    22981 cattgcttga acgcgtccaa tagcatctgc taatgaatca gcattcaata cagcatcgat
    23041 gtagtttgag cttgtgttgc ttacttgtgc ttcgcgtgct tgtttttgga ttgtatcttc
    23101 acgtttttca atacgttctt gtaaatctgc aatgtctttt actaattgtg cagattcttg
    23161 acgcaatgta tcttgttttg ctaataggtc ttgtgcttgt gtgttgattt cagaaacttg
    23221 gctttctaag gcatcgattt gtgattgtgc atctgcttgt tgatttttca agtctgcaat
    23281 cttttgatct tgctgttgta tctgagaatc aaaatcgtcc gccgcggcag cgatcggtga
    23341 tgctacggca gtcaaggtca ttgaacatac cattactgct gatattaaac tctttttcac
    23401 tcttcattcc tccgactggc ttaatttaat aaatatctaa atatatttaa gtctttctta
    23461 acgatataaa aattgtacca tagcagtgtg tcaacgatat aatagttatg ttacaaaaat
    23521 gtttcaaaac aacttttaaa aatgacaaaa ctgttcgttt cagaaaatga tcatgaaaaa
    23581 gccgcgttaa gtctagcatt tcttaagata acaacgattc tttttcgctt tcgacctaaa
    23641 aataaaaaaa gaaattattc atcactgaat aatttcttaa agggaaaaat gaataataca
    23701 aatataatca tgttcaacag cagtgtaggt cctaaaaacc ttgtaataaa atacgtgtta
    23761 tttactactg ctaatttaaa aatcaactgg accaccatcg taaacaattc ataacccgtg
    23821 acaaagatga tcatactgaa aaattcagta aagatgttga catggataac gtctttcatt
    23881 acatacatca accatacaat taaagggaga gctactgcat agataccgat aacgccaata
    23941 tagtaagcgt catagatagc cccgagaaca atcgtggtaa tcagtaaata acgtttttca
    24001 aacgccatac tgcaacataa taatgccaat atcagaaagt gggcatttga catataggtg
    24061 cctttcgacc actcccctag cattcttgtt aaatgaccat ctatcaacat caaaaagaac
    24121 aaaacgattg gcagatagta cttcattgtt tctttcttca acatggacta atcctccgct
    24181 agccgttgga caatcgtcac aactgacacg tcatacattt ctgcataagg tttcacataa
    24241 acttcccgat ccagcccata actatctggt ttcgttttaa taaccgtacc gatcggcaag
    24301 ttagctggag aattccctcc aagaccggat gtctggacaa catccccttc tttgatatcc
    24361 gtatcaccag ttaattgggt caccactaag gcatggagct tttcatcata gtttttaagc
    24421 aaaccaaacg cttcgccatt agccgaagat acccgtactg gaaaatgatt ggagctttca
    24481 ttagaggatg acagtaattc gattttagac gaagccgtat tgacctcgat cactcggcca
    24541 atcaatcctt tttgcgacat gactgccata tttgcttcga taccgtcttt agaacccttg
    24601 tctacgatca gcatgtcctg ccaactgtca ggcgaacgag taatgacatt tgccgttact
    24661 ttttcgtaac tagtcagcgt ctgattcaac tcaagttctt ttttcaacgc ttcgatttct
    24721 ctctcgtaat tcttgttttg ctgtgaaacg tcatcatagc tatcgatttt ttcttttagc
    24781 cgctcatttt cggcataagt tgaaaaaaga ttatggacag aatctactcc atttcgtacc
    24841 caccgtactg gggcagagat tgttttatca accattgcaa cactgtcatt aacgatggat
    24901 tggaagaaat tgggctttcc ttcattcgct cgctgcgcag cggtcacact tagtatcgtc
    24961 accacgatga taacaataac caaggtaata ataatatttt tattaggatt gaacttcttc
    25021 acaaagacac ctcgaattaa ttagactctt gtgttcaatt ttatcactaa atgccgtgaa
    25081 acaaaaggta agttgctcct cttaagcttt tttttagcaa ataatagatt ctgtcatttt
    25141 tagcctgaaa gacaaatttt tttatttgtt tatggatcaa tctttgcttt gaataactgc
    25201 aatcatacca tctgaaaaag aaaattctgc ggtatctgaa agaaattcgt tacttgcata
    25261 agatgtcgga tattctactt ctttattttc caatacatac ttgctgcctt ctaatgtaag
    25321 attcgagacg ggagtcaagc agcaataagc taaatacttc atatctggta tctgtcttac
    25381 tatatgctct ccaggcaaat aataagacaa ataattttga caatctctga taataagctg
    25441 atgggcaaag ggtttgaagc gaggttccat acctaaccag agattggcta aaagatgatc
    25501 caatcttccg cccgtagctc caatcaaagt gacttccgct tgcgggtaac gttcaaatgt
    25561 ttttaagata cctaactgtg tatctgtatc gtctttttct gcaggggaac gggtatactc
    25621 tttggctttt gcaaatactt ccttctgctc ttcgttcgac aatgaatcaa aatcacccac
    25681 tgccagatct actgggtagc ctgcttgaag caggtacagc gcaccacggt ctatcccgac
    25741 ataggcatcg tatttggaca gcagagactg cggccagttt tgcggattac ctccagcagc
    25801 taataaaatt ttcatttagt ctaatgcctc ttttaatcgt tcgatttgtc cgactggatt
    25861 ttcggctcca tagatatatg atcctgcaac gaagacatcc gcccctgcat ctttacagat
    25921 ttttgctgtt tctggaacga ttccgccatc tacttcgatt gcataagtcc aattgttctc
    25981 tctacgtaga tcagcgagtt ccgtaatttt ttctactgtt tcttcaataa agctttgtcc
    26041 gccgaaccca ggattgacag tcatgactag tacttgatca gccaaaggca aaacatgttt
    26101 gatcatggag actggtgttc ctggattgat aactactcca gctttaactc ctaagctttt
    26161 tgtcatttga agtgcccgat gaatatgagg agttgcttcg acgtggacag taatgatatc
    26221 tgctccagct tttgcaaatg ctggaatgta gttttctgga tcaacgatca tcagatggac
    26281 gtctaacggt aatttagtaa caggacggat tgcctgaaca atatttggcc ctaatgtgat
    26341 atttgggaca aatcggccat ccattacatc tacgtggatg taatctgcgc ctcctttttc
    26401 cactaactca atgtctcttt gtaaattggc aaaatctgca ctcaaaatgg atggtgctat
    26461 cttcattctt gtttcctcct attttcgttt accttctttt tttgcataca ttggttttct
    26521 tttttcgatt tcttgtaaga attgcaaata attgtcgtaa cgtgtctgtg cgataccacc
    26581 tgtttctact ctatgtttta cttcgcagcc aggttcttta gcatgcatgc actctctaaa
    26641 tttgcaatgg acagaagctt ctacaaattc aggaaattgt ctcggcagtt ctcctgcttc
    26701 aattgtcaaa aagtcaatcg agctaaatcc tggtgtatct gctactaacc cgccatagat
    26761 aggaatcagt tccacatgac gtgttgtatg ccgtcctctt ccaagtgcat cagaaatctc
    26821 tcctgttgct aaattcagtt ccggtgatat ttgattcagt agcgtcgatt ttcctgctcc
    26881 agactgaccc ataaagaccg atagccgttc tgggaagtaa cggatcagtt ctgtcgtatc
    26941 acccgtatga ttgggtacaa tcaccggata gcctatttta gtataggttt gcttgatctc
    27001 ttcgattttt tctgggtcgt ctgacaagtc ggtctttgtc aaaaaaataa tcggttcgat
    27061 cgactcgtat tccaaggtaa ctagaaagcg gtcaagtaga ttataagaaa atgcaggctc
    27121 tacgatactt gtgacaatga ttccaagatc aacatttgtg actggtgggc gaactaattg
    27181 attttttctc ggcaagattt ccagaagata gccgtctgtt tgattttcac tctcaaagat
    27241 cacctgatct ccgacaagcg gcgtgatttt ccgattccgg aaatttcctc ttcctcttgt
    27301 ttgataggtc tctccgtttg cgtatacata gtaaaaaccg ctgattgctt ttctgatttg
    27361 tcctttgata agtgccacct ccgtttttgt ttattttacc atacgaagag gaaagtaggt
    27421 gttattccat gcaaacttct caaagtatat ggcttgaaaa ttgatcaaaa gagatagaaa
    27481 cacaaaaaag agaatgcaac aaatcaatgt cgcattccct tctgatatat tttattcagc
    27541 acttattttg aactttctga ggtgctagct gatgaacttg tggagctgga agattcttct
    27601 tttgaagagt tgcttgtgct actggagcta cttgagctgc tagaactgtc tgaagagtct
    27661 ttttcagaac tagaagacgc tggatctggt cctttagagt aaattacgtt cacaaccatt
    27721 cctttggtaa ttgtcgttcc tgcccctggt actgtacgaa tcactttatc tttatccacc
    27781 gtgtttgaat attcggaagt ctcatgcccg atatattctg caccgacact agctaaataa
    27841 ctttgtgctt cgctttttgt atagccggag atatcattca atttaggctc tgttccttgg
    27901 cttacgacaa aattgatgta agtttcttct gctacaactt cacccgaggc tggatcctga
    27961 ctgatgatcg aacctgatgg tacagtgtcg ctatagtcat aagtagcact aatattattg
    28021 atattgaatc cttgtgtaac aagccaatta cgaacagttt cgtagttttc tcctacatga
    28081 ctactcaaag tcactgtttc tggtcctttg ctgactgtga aagtaatcgt gtctgtttta
    28141 ggatcgactt ctgtatcttc tgatggagat tgcgaaatga tcattccgct ttctacctct
    28201 gaactgaatt cctcttcttt ttgaatcaag tcagcagaaa accctaattc tttcaaactt
    28261 gcttcggcat cttcataact tttaccactg taatcatcta atttgatttt tttcgtgccg
    28321 ctactaatat acagagtgac ttcgcgtttt tgcttgactg tcgttcccgc tgccgggtct
    28381 gtcttcacta cattaccttc ttcgattttg tcatctgcaa tttcttctgt ttttgttgct
    28441 acttctaatt tcgcttttgc gagtgtttct ctagcagaag cttcagaaag atcagaaaca
    28501 tcaggaacaa caacttctcc tcgcccgcca gaagcaaaga atacagctgt tccgattcct
    28561 aaaacagcaa gaatagctaa taggatcagc caccattttt tctgtccttt ctttttagga
    28621 tcaggcagaa cttcttcctc ctctggtaag gtttcgtttt ctggcttgtc ttttggcaga
    28681 ggcatagatt tgaatgaatc aggcattggt gcatcttccg taaggggtgt gataactttt
    28741 gtttcattat ccatcacatg aggctgccat ttttcttcgt ttgcacgagc tggtgataat
    28801 actgtagaaa gatcatcaga catttcctcg gctgacttat aacggtctgc aggttcttta
    28861 gccgttgccc gtaaaatcac gttttccagt gcttgtggca catttggatc aagtgctttt
    28921 atagatggaa gatcatcttg aaaatgtttt aaagcaattg ttacagcaga ttcaccatca
    28981 aacggtacgc tacccgtcaa catctcataa aggatgatcc ctaaagcata aatatctgac
    29041 tgcttcgttg ccatacttcc tctggcctgc tcaggggaca gataatgaac agatcctagc
    29101 atcgtattcg tctgcgtgat cgatgtttca gataaagcga tagcaatccc gaaatccgtg
    29161 atttttacaa caccttcatt atcgatcagt acgttttggg gtttcaaatc tcggtggatg
    29221 atttgatggt tatgagctaa agaaatagca gaaaggatct gctgcataat atttactgct
    29281 gtttcataag gaacaggata atgtgtttgg atatatcgtt tcaagtccat tcctttgacg
    29341 tattccatca ccagatactg catgttgtct tcttcaccaa catcgtaaac actaacaatg
    29401 tttggatgaa cgagttctgt tgctgctaaa gcttctctct gaaatcgtcg aatcgcagtc
    29461 tggtcatttt gaaagtcaaa tcgtaagact ttaactgcta catcacgatc caagattaaa
    29521 tcgtgcgcca aaaatacatt tgccatacca ccgctaccga tatttccagt gatttgataa
    29581 cggccattta attttttgcc caactcgatc atacactgtc ctccttatat tcgataagaa
    29641 gaacggtgat attatccgct ccgcctgctt cattggcacg atcaatcagc tcagttactt
    29701 tatgagacaa tgggccttct tgattgatga tcgttcctat ttcttcttca gacagcatgt
    29761 tcgtcaagcc atctgaacat aacagcagtc gatcttttag ttgccaaaga tgagtagaaa
    29821 catctacttc gactgttcca ggcatgccga cagaacgtgt taaaatattt ttccttggat
    29881 ggttcactgc catttcttcg ctgatttctc ctgatttgac tagttcattg actaaagaat
    29941 gatcctccgt caattgcatg attttatctt cacgaatcaa ataagctctg ctatccccaa
    30001 cattggcaat cgtgaaccag tcatctgaca gagcggccgc tacgattgtt gttcccatac
    30061 cgttatattc cggctgttct tgtccacgct gataaatcag catattttct tcttgaatcg
    30121 attgaatgaa ccattgggcg attttttcat cgtcaacagc ttcttgtttt tcccaagctt
    30181 cgcctagatt cgttaccgcc atctgactgg caatgtctcc ggcacgatga ccacccatcc
    30241 cgtctgctaa tacagcaagc ttgagacctg aacggctggt aaatacactg gcatagtctt
    30301 gatttgtgtt acgtcgtctt cctacatctg attgatattc aatctgcatt ttttcacctc
    30361 attacttttt gcgcaaacaa caaatgaaaa atccatctgt gtaaaactga tgcggataca
    30421 aagtcaacat tttctcttcg attgatgatt gtagcatagg attggtcaaa acatcaatcc
    30481 tctcaaaatc agggtgtctt tccaagaaag cagaaacaac gtcttggttt tcttctttta
    30541 agatcgtaca agtgctataa gtcagaatac cggaagactt taaagttggt gcgcagcttt
    30601 ctaaaatttc caattggatt tttggtaaat tcgctaattc atccggctgt tttttataac
    30661 gaatatctgg ttttcgccga agcagcccaa gacctgaaca aggcgcgtct actaaaatcc
    30721 gatcaaactg ctctgcttcg aactgtttac tgacttctct agcatccatc ttttgagcgt
    30781 agacagcaga agagacacct agacgtgctg cattatcttc aatgagtttg actttgtgtt
    30841 cgtgtacatc taaagcgacc acttctccac cgcatgacgg atctaaaaaa gaagcaatat
    30901 gcgtcgtctt acctccgggt gctgcacagg catctaagac atgatgttca ggctcgattt
    30961 gcatagacgg cgctacaagc atcgaacttt catcttggat cgtcatgacg ccatcgtgga
    31021 acaatgagct agaagctaaa tgcccttttt tcgctactat accgtatgga ctgacttggc
    31081 ttttttcagc tgtgatctct tcttcttgca aaacagtgat ggcctgatct ctggaaagtc
    31141 ggcgtgtatc tactcgggca ctagcatggc taggctgata tagcgataaa ccgagctttt
    31201 cagtttcttc gtatccgatt tgatccacca gtcgtttcgt catccataga ggcaggctga
    31261 ttttgacaga aagtctttcg ataggatcag caatgccttg cagatctggt gctccttgac
    31321 gctgataatt cctcaagaca ccatttacaa atttccctgt cccaggattt ccttttactt
    31381 ttgcgatttc gaccgcctcg tttaaaatag catgtgcagg gactttatct aaaaattcta
    31441 attggtatac agaaagataa agaagcatct tgacccagtc atccactttt tttgctttag
    31501 cgatcaatgg tgcaacgtaa aattccaata gtcgctgatg gctaatcgta ccatagatca
    31561 attctgtaaa taaacccaca tctttttgat ttagctcgct ttgtttgatc atctcattca
    31621 acaaaagatt cgagtaggcg ccacccttgt tcactcgctc taatgtcagt aatgccatat
    31681 atcgtactga ttttttcatt tttttaggga tttttttcat tatttcacct gctgaccaat
    31741 ctgaacttgc tgaccgcttc cgttaaggaa atcatgtacg gcctgttttc ctttaccagc
    31801 tggctgtaat tcattgatgg ctaagacggt ctgtttaccg caagcaatcc atagtttttt
    31861 tttgtctttc cggatgatcg taccaggtgc tttgtctgta gtttctgcca atacttcaac
    31921 cgataataat ttccagcgta tgccctcata ggtcgtgaat gcaattggcc aaggacgcat
    31981 tccgcgtact tggttgtcaa tttcttctgc agttttatgc caatcgattg cttcttgttc
    32041 ccgtgtgatg tttggcgaaa aagttgcttc tgactcgtct tgaggtactg gtttttgtcc
    32101 atccaaaata ttgggcaatg tttctagcaa tagctttctt cctaaaaggc taagcttttc
    32161 aaacatcgtc cctacatcat cttgtttagt gattggtatg ctttcttgcg catagattcc
    32221 gcctgcatcc atttttttga tcatttccat gatcgttaca ccagtttctt tctccccatt
    32281 catgatggca taatgaacag gcgcacctcc ccgatattta ggaagtaaag aagcatggac
    32341 attgattgcc cctaattttg gtacttgcaa taacttttca ggcaagaatt ggccaaatgc
    32401 cgcagtgacg atcacatcag gcaccaattc aatgatttct tccatttctg gcgaaccgga
    32461 gattttctct ggctgcagca cacggatacc gtgcttcaga gccgcttttt ttaccggtgt
    32521 cggcgtaatt actcgtttcc gcccaactgg acggtcgggc tgtgttacca ctgcctggat
    32581 ctcgtaacct gattctatca gcccttcaag aatcggcaca gaaaaagcag gtgtgcccat
    32641 aaatactagc ttagtcatca agatgttcct ccatatattc ttcaagttct tcttccggga
    32701 tctgctgtat cattttctca atgaacaaga taccgtctaa gtgatcgatt tcatgctgga
    32761 aggcacgggc taaatagcca aaagccgtca cttctatctc ttctccgtct cgatcataat
    32821 aacgcacggt cacttcatct gctcgcttga ccgttccata gacatgcgga atactgagac
    32881 aaccttctac gtcaaggctt tcaccttttg cttcgatgat ttctgggtta atcagttcaa
    32941 atttctcgcc ttcatctact tcgatcacag caattctctt gttttgtcct acttgaggag
    33001 cagcgatccc tattccgtca ttcgcaatca ttgtctcata taaattgtct aataaagcga
    33061 ttgtctcgtc cgtgattaca tcgattggct gagcagttct ttttaattta tcattagggt
    33121 ggatcaatat aggatagcgc ataatttggc cctttcttaa ataaagttta atggttcgtt
    33181 gtcaattgcc acaaaaagac cttgtcgctg ttctttctgg cttccattca aaatttcatc
    33241 caaaacatga ggaagattcg gttcatgttt atatttgatg attagttgat aataatatcg
    33301 gtttttcact ctcaaaatca tgctgggcgt tggccctaat agcaagcttt gagggcttaa
    33361 cacttctttt agctgattgg caatctgaaa gattttcttt gccgctactt gttcttcagg
    33421 atggctggcg gttattttca cagtaaagta ataaggagga tagcctccac gatgccgtac
    33481 atgcatttcc tgctgataaa actgctcata attttgtttt ttagccaatt ctatggcgta
    33541 atgttgagga ttgaatgttt ggatcacgac ttcgcctgct ttttccgctc gccctgctcg
    33601 tcctgaaact tgggtaagca attggaatgt atgctcacta gaacgaaaat ccggtaaatt
    33661 cagggaggta tcagcattca acaccccaac taatgtcact tctggaaagt ccaaaccttt
    33721 agcaatcatt tgtgtcccta ataatatatc tgcttctttt gcaccgaatt tttgtaaaat
    33781 ctgttcgtgt gccccttttc ttcgagtggt atctacatcc atacgcaaaa tcctagcttg
    33841 cggataaagt tctcggagtt cctcttctac tttttgagta cctgttccat agtagcggat
    33901 tttattgccg ccacaattag gacagcgatt gggaataggt tcttcatgtc cgcaataatg
    33961 gcagcgcatt gaacgtgtat ccatatgcag tgtaagagag atatcgcaat taggacatgg
    34021 aagaacaaat ccacagtccc tacacatcac aaaagacgaa tatcctcgac gattgagcag
    34081 taggacagtt tgttcttttt tgtctaatcg attttgtatt ttttcctgca aattagcaga
    34141 aaaagtagag gtccgatgat tctgaaactc ttcacgcata tctacgatct caatagctgg
    34201 aagctgtgca gctgctttgg ctcggtggtt taactgcaat aactgataaa cgcctttttg
    34261 agctcgtgct cttgattcta aagagggcgt cgcgcttcct agaactattg ggcaatgatg
    34321 atatttactg cgccaaattg ctagatctct cgcatgataa cgcggtgtct catcttgttt
    34381 gtaacttgat tcatgttctt catcgataat gatcagcccg atatttttca gcggggcaaa
    34441 aatagcagat cgtgcgccta ctactacttg cgcttcttcc cgctcaatct tgcgccattc
    34501 atcatatttt tcaccttggg aaagtccgct atgtaagacc gcaactgatt ctccgaagcg
    34561 tcctttgaat cgctcgacca tttgcggagt caatgcgatt tcaggcacta acataatagc
    34621 cgttttattt tctgacaaaa catcagcgat tgcctgaaga tatacttctg ttttcccgct
    34681 gccagtgatt ccctccagca aaaagacctg atctttttgc tgctgacctg ctgtgatgat
    34741 ttgttcgaca gcattttttt gttctgcatt cagttccaat gccgtcgttt ggtcaaatac
    34801 tcggtcttta taagggtcgc gataacgttc tgattctata aactccagcc agcccttttc
    34861 ttttccttga ttcaagacag cagtactgat tcctttattt ttgaaataag caattggttc
    34921 ttcttggctc agttcagata aacacaaaag aagttctttt tgtttcttgg cattttgccg
    34981 taattttgcc cattcttctt cgatttgctt ttcagttaac aaagaacgga ccaaacgaat
    35041 cgtttttact ttatttcgtg tatggacttc atatttgata tctactaatt gctcttggcg
    35101 ccagcgaatc aattgagaaa ggctgccttc ttcttctgct tccttccagg aaatcacttc
    35161 tcgctgatca aacaatacct gaacttctgg tgtgtctgcc aaaggataga tcaatttatc
    35221 atattctgct ttcatcacac tcggaagcat cgtttgtaga caagtgattt tgaatgcgta
    35281 agtaattttt ttcatataat cagctaatga aagtaattct tcattgacca ccggagcaag
    35341 gtctagcaaa cgaataactg ccttcaaaga tggattagct gattcttctg atttttggat
    35401 agccataaca aatccttgga catgacgatt gccattacca aaagggactt ctactcgcat
    35461 cccgacttgc aaagctgttt ccatttcaga gggaaccaaa taagtgaatg gctgatcggt
    35521 ctgcatagta ggtacgtcca caatgacttc agctgttaat gtcatggttc gtttcctcct
    35581 ttttttgtct tttcttatca agcgacaaaa agttccttgc ctattttact agagatcgat
    35641 ggatttgtct tatcttctgc caaatcctaa caaaaaatta acagcagata agaaaaaaaa
    35701 gaactgtgtc aaaaagttca gacacagcct tttctaccag acaataagtg gcgaatgttt
    35761 gaaaaggaaa cagctgggtt tgcttttctt tttagatgtt cgctctattt ttctttatta
    35821 cattttttgc tcttcacgga tacgtgattc caattcgtgt tgttcacgct ctttttgtgc
    35881 ttgacgttcc tcttcttcca tcttcaaacg ttcacgtttt aattcaggat gtggatcatt
    35941 gactacattt cctgcatcga tttcttctaa agcttgaccg acgcttttta ctgaatcaaa
    36001 agaatctaga gtaggctgtg cacttgcatc caattcatgc gcgcgtttac ttgctaaaat
    36061 cactagagaa tattttgaat ttacacgatc taatagtgag tcaattgaag gttttaacat
    36121 cataagacta catctccttt aacattttaa tatatttacc gattacgcga tctactcgaa
    36181 aatgttcact ggcaataatg tttttgattc gttcaactgc tagcggcact tcatcattta
    36241 caacagcata gtcgtaaaga gccatcattt cgatttcttc ttttgcaact ttcattcgtt
    36301 tttcgattac ttcatctgca tctgttcctc ggcctacgat ccgtgatttt aattccgcta
    36361 aatctggcgg agtcaaaaag atgaatacac catcgggcac tttttctttg acttgttttg
    36421 ctccttggac ttcaatctcc aagaaaacat cttttccttc atccaatgtc ttgttgacat
    36481 atgacaaagg agttccataa taattcccga catattctgc gtattccagc atctctccag
    36541 cttcgatcat tgattcaaac tcttctttgc ttcggaagaa ataatcaacg ccttcgacct
    36601 ccccttcacg cattttacgg gtagtcattg agatcgaata ctgaaaatca ttatcctcac
    36661 tctcaaaaat tgcttttcgt actgtgcctt ttcctacacc ggatggacca gacaacacga
    36721 ttaataatcc acgctctgac atgacgacgt cctttcaact agtctttttg tacttatcgt
    36781 ttattttgca ctttttttct gcaactttca aggttatctt taattatagc tagaaattgg
    36841 taaaaaagct accctgtacc aagaggtcgt aaaaaagctg tcctgcatca agtaataaga
    36901 acagccaaac ataaacagct tctcatgttt ttcgtttggt tggggttatt atcgcagatg
    36961 caagcttttg aacgccgtgt ataagaggtc gtgaagaagc cgattagttt cgagtatgaa
    37021 gaaaaatttt gtgaaaatag tttctcacat ttttgcataa atttggctta ataccgagaa
    37081 aatggttttt gaacatcact tattcaaaat aaaaaaagat tgtgacacga attttgtcac
    37141 aacctttaaa tgtattccta gagcaaagaa gctaagcgaa gaaatccaat tctgtttatt
    37201 tattgtattt ctttgttcag catccttgct aaaagcccat attggacaaa gtattcacta
    37261 cacccatgat ctcatctttt cgagaacgtg ctttttctgt cggatcttct acctcttctg
    37321 tgtcaattcg aacaataaat ttccgattca tcgtcacgta agcaccgtcg ttgatcaaaa
    37381 taaacagttc gttctcatta tagtctgcac aggcatcttt ccatacgtca aagccgtttt
    37441 tttcagaagg gatatcccgt ttaaccacag tttttccact taattcgtgg aacgttacgt
    37501 cataatattt cattatctct acctctttcg tcattcaata ttttgtactt gttctctgat
    37561 tttttctaag atcgtcttag actggacgac ttgattttta atttcgattg catttgattt
    37621 ggaaccgatc gtgttgattt cccgattcat ttcttggatc aggaaatcta attcccgacc
    37681 tacaggacat tgtgcttcga taagttcatc tagtttttgt acatggatcg ccagacgatc
    37741 cagttcctcg tgaatatctc cgcgttccaa caagatggct agctccgtca acaaccgttg
    37801 ctcatcgact ttcgctccaa gaaattcctc cagctttttt tgatacctta tttgaaattc
    37861 cttttcatag atttctacaa aactatcgag tttttttagt acttctttga attcttcagt
    37921 attctttttc aacactaaag ctaaagcttg accttctttt tctcgactcg cctcaataga
    37981 atcaagtgcg cttttcaatg tatctagagc taactgtgcc aattcttcca tgctctcttc
    38041 cggtttttct tctaccgtta cgaagttttc gtccagcacg aagcgttccg ccatccgact
    38101 aattgacact tgattttgac taccgtatcg ttgttgaatt ccgtctgtca attgagtgat
    38161 aagtgaatca atcaattccc agttgatgac gatctgtttt tcgtttttgc caatataagc
    38221 tagattcaca aatacttcga ttcgaccgcg gcttaactgc tgtttaataa gctgacgaaa
    38281 atcgttttca acaaagttca ggattttagg acttcgtatt tgaacatcta gaaaacgctg
    38341 gttgacactt tttatttcaa tatctaactg atacgctttt gtttcgcgga tggctttgcc
    38401 aaaaccagtc atacttttca ttcgacaggg tccttcctca ttacatattt tctattgctt
    38461 tttgcagttg ttcaaactct tcgttcgtca atgtcaggcc tttccccatt ttttcatggt
    38521 ctggcgccca atctcgaaga tcgaattttg gcgggcgacc attccagctg actaggttca
    38581 gttctttacg ccaccccttg ttgttttctg acaatatagc gatttcttct acgatttcat
    38641 atgaaaattc ttgtgccatg gttgttcctc cttgagataa tataaatata ggatcagtaa
    38701 tgtgtcaact ggttgcttaa gcaattcatg ctgcaaacga tccttgcgtt ttccttgtag
    38761 cagataatca aaataaacag ttttcgtgcg ctcattttgt attttttgct ggtattttcg
    38821 ataccttcgc cattcttcag tacttaattg accaatttgt gccaataaat catccggcat
    38881 actttttata tcttgttggc agatcatttg aatcatcatg tctacttgat agatttcatt
    38941 gggcagtaaa aaatgttttt ttgctaaaag ttctagcatc gccaatccgc atgtctctgg
    39001 tacgaccctg ttcttatata aattacgcag tttttgccaa aattttatgc ttttgaaaaa
    39061 agataattct aactgaattt cttttgttaa gtaagacaaa aatcctcgcc agtatgttct
    39121 tgcaggttta acagaatgaa atgtatacca gttcccatag taatagccta atcgtttttt
    39181 catttccaga tagcctaatt gtaaatttaa ttggttcctt tggctatcaa aaagcagaaa
    39241 gctgcctagt gtccacaatg tttgacattt ccaatggata aaaatgtctg gcatacgaat
    39301 ttttttcgct gggcctggcc cttgcacatc tacgacaaat gcctctgttg ctcctttgtt
    39361 aatcgcaata tcaataggta ttttgttgcg atacccaccg tctgcatatt tattttttcc
    39421 gatctttcga taagccatag cgggataaaa tgaagcagag gcgagtatcc aatctggtat
    39481 ttcttctgtt tttgtctgtt ggatatcagt cactacttcc gctagttctg gcagtttagt
    39541 agacaccgta tataaacgta ttttgggatt atgtttgagt aaggacaaat ccaaattgtc
    39601 tttgaccatc ttttccaatg gagcagaaga aaccccgcct tcaattagtg ctgttttcgt
    39661 catttggcgt ctttctcgat agaagcgttc acgaaggtct tcaactgcag ccatttctgg
    39721 taacgcaagc acttgtcttg tcgacagctt tttccataaa ttcacagctt ttttcatatc
    39781 tccttgtaaa atcaatgcgc cgttcaacgc acctaccgag gtacctgtga taatctcaaa
    39841 gttgatatca tgttccttca gcgcctgcca cacaccaatc tgataagcac cgtgcgctcc
    39901 tcctccacct aaaacaagtg ctgtatgata gaccagcttt ttatttaatt gtgtggttcc
    39961 ttgatagccg tttttatgaa aaatacgcaa ccattcttct gatagaggag attgaaataa
    40021 aaaacaacag ttttctttaa taaaaaaacg agcgcaagct tccatatacc gaaaaaattt
    40081 tttccattca aaagtttcac cttcaatcaa cagattatta aaaataacat ctcctctact
    40141 tttagcaata gtaaaataga cggtatattt tttcgatact gctttaaaag cacattgctt
    40201 ttttgcagaa cgccaaaaag cgtctctact ttcttgatga ctttgaaaaa atggaagggg
    40261 ttgttttgct tgctggatag gcgaatacag cgacattttc tgtgaaaagt aaactttttt
    40321 tatctccatc gcgctctcct ttttcttcaa gtataccagt acgtcataaa aaggtcatga
    40381 gtctcgtatt cgactttgta gattccataa gaaaacaatt cataaaacct cctttaaata
    40441 aaaaaataca aaaatcacaa aaattaattg aaaatgagag tgttttcaat gaaaacgtga
    40501 ttttgtaatg gaattttaaa ataaaagaaa caagcttttt taatgcaaat gttgtaaaat
    40561 aaaagagatt aagaggaaat aagaggagga acatgatgac tgagtcagtt tatgtacata
    40621 ttgataccac aagtaatgct gttttaacaa aagggctgac tgctactgac tttgcaaaca
    40681 gtatcgtgca ttttcctcaa aacttgctct tgcttgatcc atctgcttct gctggagaat
    40741 atgaatccca tacagggctg aaagtaatcc gtggtacaga aaatattcag cgtttctttt
    40801 cctcttctcg taacaggcgt ggattcgatg aattgaagtg gatcgacttt actgatttaa
    40861 cgatgctgaa agaattgaca cctttagaaa tttcagaatt attatatttt ggtcatatga
    40921 aaacacatct tcattcgccg tttttttata aactacagaa taattttgta tacttcgatc
    40981 ttaatgatca gctgaatcgg atttattatc gctatttaga tgaattttat aggatttttg
    41041 ctagtaaatt aagttcgatc ttgtcagata agatcaatgt aaaaaaatct tttttcaaaa
    41101 aagaaacacc tgttgaaaaa atcagtgtgg aattattgaa agaaatgcgt aatttgatgc
    41161 aggaagggat cattttttct tttgatcaag ttggtttgat cgatggtaaa tatcgtatcc
    41221 caatctatgt gattgaagat tatatttgga aattaaaagg cacccggtat cgagaagagg
    41281 aaatcatcgc tactttaatc tactctgtca ccgatcgaca ctggcaattg gtagaagatg
    41341 ccgatctttc ttatctgcca ttgaagtaga tctatttctt atcaaaaaat aaaaaggaaa
    41401 caagaaacta ggacatgatt ctgtctcaag tttcttgctt cttttttatt tacagctcct
    41461 gtcgtttatc tggcacaaaa atcgaaggag tcgtttgttg gatccctaat aaaacgatga
    41521 tcgttacaat agctgtactc aacccgctgg caccattcat tacgaaagaa aagagccaag
    41581 gattcatccc ccatagtgca tacgctcccc agaaaaccac tcctgcaata aaatgccaaa
    41641 aatatctgga aagtgcgcca atcaatgcac caaacacgat gctttttcta atttgtttcg
    41701 tattatcgtc tacatagcct ttttggacat ttgaagccat gagccctgct gcgcctgcaa
    41761 aagtataggc aatcgggtac tcaatcaaca cttgaacgac acttaaataa taaacttgtc
    41821 ccaacggaaa atgtaggatg ccccaaatga aacctgccag catccctgcc tttgtccctc
    41881 ttcttaacgc aaaaagagtc aatggaatct gccctaatga aatagaaaaa ctgctgccga
    41941 tctggatcgg aatcaacgac aacaccatcg ctaacgctgc aacaatcgtt ccttctaccc
    42001 aaactctatt ttttcccata aaaaaacttc ctcctttgaa taaaaaagtc acaaaggagg
    42061 aagcagcttt cgaaaatagt caaacagctg tttattcaca attcctacgc tcgcataacc
    42121 gatacaggta cgaagggttt agaaatagat tcaatctcag cccaattgga ctcccctttg
    42181 tgagtttatt tattatttat tttttgtttc aaacaatgga ctaactggtt tgttttcatg
    42241 gatacgtttg attgcatctc ccattagtcc gccaacactt acttcatcga ttttgtcgat
    42301 tttacgatct tctggaagat agatcgagtc tgtaacaact agacgctcga tagctgaatc
    42361 ttctattctt tgtaaagcag ggccggataa tactggatgt gtacatgaag catacacact
    42421 agttgcacca gcttctttca aagcattggc agccaatgtg atcgtacctg ctgtatcgat
    42481 catatcatcg atcagtacac aagttttgcc tttgacttgt ccaatgatat tcattacttc
    42541 tgcaacattt gcttttggac ggcgtttgtc tatgatcgca atcggagatt tcaaaaattc
    42601 cgctaattta cgtgcccgtg tgacaccacc atggtctggt gaaacaacga caacatcatc
    42661 gcctttgatt cctttttcta agaaataatt ggcaataagt ggcgcaccca tcaaatgatc
    42721 gactggaata tcaaagaaac cttggatttg gactgcatga aggtccaaag tcagcattct
    42781 tgttgcacca gctttttgaa tcatgtttgc tactaatttc gctgtgattg gttcccgtgc
    42841 acgtgcttta cggtcttgac gcgcatagcc ataataaggc atgactacgt tgattgtttt
    42901 tgcacttgct cgtttcagtg cgtcaatcat gatcagcaac tccatcaagt tatcattgac
    42961 tgggctgctc gttgattgaa taacatagac atgcgatcca cgaatacttt cttcaatgtt
    43021 tacttgaatt tctccatcac taaattgagt aacagatgat tttcctaact cgacgccgac
    43081 tgctgctgca attttctctg ctaatgggcg attggaattt aacgcaaaaa tttttaatct
    43141 tgggtcaaag taatgttttg acatggggac ctccactttc tttttcacaa ctctagaatt
    43201 ctacctaata aatagtagtc atatttttta aataaatcaa gtgattttgc aaaagtctta
    43261 gtttagataa gggagttttt ttgcatatcc ttctttattg acttgtcttg ctctcgcaat
    43321 tgccagcgca tattctggaa tattgtctgt aattgttgac ccggcagcaa tcgaactgtt
    43381 tttagctacc tcgacaggtc cgatgatatt cgtgctagaa ccaataaagc tgtggtcgcc
    43441 gacagtcgta tgatgtttgt tctttccatc atagttgacg aagacaacac cacatccgac
    43501 attgatttct tctcccagcg tagcatcacc aacataagtc aagtgaccga ctttagttcc
    43561 tttgccgatt tgagcatttt tcacttccac aaagtttccg atatggacgt tttcgccaat
    43621 ttcagctttt ggtcgtaaat gtgcataagg tcccacatct gcatgtttct tgacatggct
    43681 gctttcaatg actgagtttt caatgacgac gtgatcctca atcctactgt ctacgatttt
    43741 tgaatgtgac ccgatgacac aatcagaacc aatgactgta tttccttgga tttgtacacc
    43801 tgcttcgatc aatgtgtctg gaccgatttc tacgcctgca tcgatgtatg tcgttgctga
    43861 atcgacaaag cttacgccat tgaccatatg catctggtta attcgctttc tcatgatctc
    43921 atttgcttta gctaacgcga tccgatcatt gactcccatt gattcttcaa aatcatccgt
    43981 ttgataagca gcaactgtat ggccttcttc ttttaagatt tcgatgatat ctgttagata
    44041 gtattcacct tgagcattgt ttgttccaac tttgcttaac gcatcgaaca aagcttcgtt
    44101 gtcaaaacag taagttcctg tattgatttc ttgtacaaga gcttcttctg gtgttgcatc
    44161 tttttgttcc acgatttttt ctacgatccc aatatggtca cggatgattc gtccatatcc
    44221 tgttgggttt tctgcttgtg ccgtcaagat cgttgcactt gcattttttc cttggtgata
    44281 ttcaaaaaga ttgttcagcg tttcagtagt caataatggt gtatcgccac tgataactaa
    44341 cgttgttcct ttttttcctt ccaagaaaga agcagcttgc aaaacagcat gtcctgttcc
    44401 caattgttct gcttgtaacg catatttact gcgttctcct agttgtgctt taacttgttc
    44461 tgctccgtgt ccaacgatcg taatcacttc atctggtttc gtttcactga cccgattaat
    44521 gatatgttct accataggtt taccagaaac gggatgtaaa actttatata attttgactt
    44581 catgcgggta cctttccctg ccgccaaaat aattgcataa cgtgcgtcca actgcgtcac
    44641 tcctaaatat agtttgctga tttcagttta tcccagtata cccatttttt caacaaaaca
    44701 agtgattttc ttttatccca gcgttttctg gataaaaaaa tagatagacc ataacgggcc
    44761 tatctatttg gtaaccggtg ctctcctgcc aactcctcgg tcacaagtca cactactcat
    44821 aaaacatgaa aagctgtttt ttgaaatcgt ttcttgtgac ttagagttaa acggtaggct
    44881 tacaacctct tcattaaacg tttttcaatc agctgacctt cggtattagc tcaataaacg
    44941 gcaaaatatg aggagcaatt tttccgttta ttgagctaat actcaggaca ggacgctgat
    45001 ttcacaacct ctagataaac ggtgttcaaa agccagtttc tcggtattaa gccaaattta
    45061 tgaaaaaatg tggaaagcca ttttcacaaa atttttctta ctactcgaaa ctaagcggct
    45121 ttttcacaac ctcttattct gaaaaataat ttcctggcac aaccgtaata tttttcgttt
    45181 gagtatctac atctttgaca taaagcagtg acgtataatc atcgatggcg cgatgaccgt
    45241 tgaattttga ttcggcaaat acagtgatgc caacaagttc tgattcgaat tcttcaatca
    45301 agctcttcat tccgttgact gttccgccgc ctttcatgaa atcatccact acaaggacac
    45361 gtgaaccacg tttcaaactt ctcttagaca gttccatctt ttcaattctt tcagaagatc
    45421 cagacacata gttgacactt actgttgatc cttctgttat ttttgagtcc cggcgtacaa
    45481 taacgaatgg cgcattcaga taataggaca cagcttgggc aataggtacg ccttttgtgg
    45541 ctacagtcat tacagcatcg attttttcac caaggtattt agaagcaatg attcttccaa
    45601 cttgacgcag cagttcaggt tctcctaaca aatcagagag ataaacatat cctcctggaa
    45661 gcagacggtc ttgttctgat agacgttctg ctagagattc aatatatttt ttcgcctctt
    45721 catatgaaat ttcagggatg aacaatacac cacctgcagc acccgggatt gtttccaagg
    45781 ttccataccc tcgttcttta aatgttttct tgatgattcc caaatcttca ctgatagaag
    45841 atttagcaga ttcataacgt tcggcaaagc ttgttaagga aatcaattca tgcgggtgat
    45901 tcaataaata ctgtgtcatg tcaactagac gttcactgcg acgtactttc acctattcca
    45961 actcctttta agaaatttta tcgttttaca ttatataagt ttttcttcaa aaattcgagc
    46021 attttatgaa aaaataagaa aatagttcgg tatttattaa aataaaaaga agcctataaa
    46081 aaatttttcg tttttataag gcttcttttc tttataattt agttattttt tcttctgaag
    46141 gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa gactaatgtg
    46201 attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga cagcatccct
    46261 agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc taatcgcata
    46321 ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc aatcgggatc
    46381 atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa atgaacgggt
    46441 agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg ccgtttgaat
    46501 aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac ttgctcccat
    46561 gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga attccctccg
    46621 ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat ggcaatggag
    46681 atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc tgctaataca
    46741 acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa cgctacccct
    46801 gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat cactaaaaac
    46861 acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc tcttctcatg
    46921 aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg atctgtctgt
    46981 ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat ttcccatgga
    47041 catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca tccatacctg
    47101 ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc gctaaactga
    47161 ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata tcccacatcc
    47221 ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga cgcttgaacc
    47281 agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta ggaaaacctg
    47341 cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt ccttcttgat
    47401 ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac gatgctttca
    47461 ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca cccgcatcta
    47521 catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc aaatcagata
    47581 tttcgatata acgcacctta caacctccat tctaaaactt aattgatact ttcttttaaa
    47641 gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat ttgttcatta
    47701 gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt cgacaatgtc
    47761 tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt gtttttcttc
    47821 acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg tgaaacgccc
    47881 gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc agcatgctga
    47941 gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg atccagtgct
    48001 tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt atctggatat
    48061 ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac cggatcgagc
    48121 caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc ttcatgttcg
    48181 tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat caaggtctgt
    48241 ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga actattatac
    48301 acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc gaaatcatgc
    48361 ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac gatctctttt
    48421 gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt tttgtctgct
    48481 tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac cgtagctgtc
    48541 aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt ttacgattta
    48601 ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc atcaatttct
    48661 gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg ctcatatcta
    48721 gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca gtttttcatc
    48781 acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt cctcacaaaa
    48841 accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca aggcaaaaac
    48901 ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca tacgctcttt
    48961 gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt ttcccatttt
    49021 tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt ggatgtcttg
    49081 atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga cactcattct
    49141 tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga tttcttcccc
    49201 tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg taccgacttc
    49261 caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt ggttgatccc
    49321 tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta ctggaatatt
    49381 cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta gcaataaagc
    49441 agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg tttctacaat
    49501 gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta cgctcgacat
    49561 caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca gtcctaaatt
    49621 tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa aagtctaagt
    49681 cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct agtggttgat
    49741 tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa caagttctag
    49801 tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc ctttttcttt
    49861 tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt tcctataagc
    49921 aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag cagactggaa
    49981 ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt gaaagaaaga
    50041 aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt ccgagtagcc
    50101 cattttctcg tatacaataa acagattggc taacagatag tcagctaatt cctcagattc
    50161 tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg gctgagcggt
    50221 gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag ataatacata
    50281 tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa gccatttttg
    50341 tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc aagtaaaatg
    50401 gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag acaagtcttc
    50461 tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac ccaattcatg
    50521 aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc ctaaacaatc
    50581 tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc caactggatc
    50641 tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt gatcttggtc
    50701 gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc ttgtagctgt
    50761 gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac tgccaagctt
    50821 cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg agatgcccaa
    50881 accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat gatttcctgt
    50941 tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa cgataaacaa
    51001 aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga attttgttcg
    51061 ataaaattct tttctggata accacacagc taacagaatc aagacatata ccaatatcaa
    51121 ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta aagcaatcgt
    51181 aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga gtaataaaaa
    51241 gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca ataatacttg
    51301 aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca tcatgatccc
    51361 cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa acagtcgcgg
    51421 aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca atagaagtcc
    51481 cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa ctactgctac
    51541 atcttgccga acagacaatt gactcattcc taagatcatc aaaacgtcaa aagtccccat
    51601 tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca taggatagat
    51661 cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata ccgcaagggc
    51721 tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg gataaaactc
    51781 gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg ctaaaaaact
    51841 accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa taaaaaagac
    51901 atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata gtgcgacttt
    51961 tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac tagcccgcag
    52021 acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg ttacccacgc
    52081 agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta agactctgat
    52141 cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca gaatcatgag
    52201 caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc aactcatgcc
    52261 attagcaata tttgcgactt gatttgccac aaagactaac acggagccga aaaaaatcag
    52321 ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt tatttttcac
    52381 attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc ttatttattt
    52441 taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa agatatccta
    52501 atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat atggcacaag
    52561 ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg ttcgtttcca
    52621 gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat gcatgcaaaa
    52681 gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa ccaaaaatca
    52741 ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc atttctattg
    52801 cttcaggaaa atcattaata gatttagaaa cagcgcttga agatcctcag gcctccatcg
    52861 tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg atttgcaaaa
    52921 atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa gcaatcggca
    52981 gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct ggcagctcac
    53041 ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg aatggtttgt
    53101 ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt caaaaattcc
    53161 tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct ggcggtacaa
    53221 ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc atcaaaggaa
    53281 tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga tagcaatgtt
    53341 ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt cttttgtatt
    53401 ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac tttgatgtgt
    53461 ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa acgaacagcg
    53521 tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc agcttgaact
    53581 gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact tcttaaacga
    53641 cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga gagcgcatct
    53701 gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg atgagaagcg
    53761 atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc accgatctca
    53821 acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag caacccggca
    53881 cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc taattttgca
    53941 acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg cagacgtccg
    54001 atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc tgcctcttcc
    54061 ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat ttcttcgata
    54121 cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg tgcgatttct
    54181 cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc gatgattaaa
    54241 tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc aatgatacga
    54301 cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga aacttgatct
    54361 gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc tgcttcttct
    54421 ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag ctcttcttca
    54481 gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat tttttctagt
    54541 tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc aattaattgc
    54601 tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt ttctaacgag
    54661 tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg agattttaat
    54721 tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg attttcttcc
    54781 ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc actatcgatg
    54841 attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga ctttgcgacc
    54901 ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat gttgaatacc
    54961 ataaaatcca cctccatact atctttttca tttttatcat ctatacagct tctatgataa
    55021 attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa catgcacaac
    55081 tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa acggctttct
    55141 acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat aggtaaacct
    55201 ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata tttttatttt
    55261 atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa aaaacggcag
    55321 gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat ttttattctt
    55381 ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact tcttcaccaa
    55441 taccataagc tgctctaact agagcagaaa cttctgccat catttcagga tgattagcca
    55501 tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa gaataccaag
    55561 caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct ccttcttgtg
    55621 agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt gctactttgt
    55681 tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt ttcaattgtt
    55741 ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt cctccaggag
    55801 tgatttctgg attcccaaac atcacgccta ctttttcacg gatttggttg atgaaaatag
    55861 cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga gacatcaaac
    55921 gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct cgtggaacta
    55981 aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact aaagcatcag
    56041 cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca tcgatattca
    56101 cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg aaagcggccg
    56161 ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt ttacctgaac
    56221 tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca cctaaagcga
    56281 catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt ttttcgccca
    56341 atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca gcatctaagg
    56401 ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat cagagcaaca
    56461 tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac cgaacaaata
    56521 ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct tgcataaccg
    56581 cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa accacgccgt
    56641 ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac gtgtccggtc
    56701 cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt gcttgaatgg
    56761 ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc tccggatcaa
    56821 tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct ggaaatactt
    56881 cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc aaactttccg
    56941 ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt gctagcgaat
    57001 tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt tcttctaatg
    57061 ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt cgtaatgtca
    57121 cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca atcagatctt
    57181 ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact ttagaaatta
    57241 gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc acaaacattg
    57301 gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct gtttgataaa
    57361 aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg ataatctggg
    57421 actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat gccaataatt
    57481 ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca gttgcttctt
    57541 ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt tcacttcttg
    57601 tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca actgtttgat
    57661 aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca ttcgtattca
    57721 cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc attacttccc
    57781 gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag agggcaagga
    57841 gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc tcctgccaaa
    57901 acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg aaattatccc
    57961 ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata cttacattga
    58021 tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga tagtaaagat
    58081 cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga atgggatatt
    58141 attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt ttcccggcca
    58201 agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg tgacggctaa
    58261 ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt caaccaacat
    58321 gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact tgccaaaatt
    58381 agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga tactagctaa
    58441 agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc ctacgttaaa
    58501 ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca tacaaattct
    58561 aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc ctattctacg
    58621 tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt tattcaaagg
    58681 agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga cacagatttg
    58741 tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat ttatacgatc
    58801 attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt tcccctggat
    58861 taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca ccaatcgtga
    58921 tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt gctgccagtg
    58981 tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga ttgacagcag
    59041 taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg gcactgccag
    59101 aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt gttgattcta
    59161 ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc tcgactgatc
    59221 cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga cgatcttgcc
    59281 aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat aaaatgacag
    59341 gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct tttctagaag
    59401 tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg cttttcccat
    59461 caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat tgccgaataa
    59521 atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg attgcttcca
    59581 aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt tttttattca
    59641 ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca tcttctccag
    59701 tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt tgggtgctgt
    59761 gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct gccaactcct
    59821 cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact tgttccttgt
    59881 gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca atcagctgtt
    59941 cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt atgtttctct
    60001 aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt caaaagcttg
    60061 catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt tacttggctg
    60121 ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg tgttccagaa
    60181 gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat tttcgtaaat
    60241 tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta cttcgtttga
    60301 ttttatttta atataagttg attaaaagag agcatgattt gttttatttt ctcactaatt
    60361 tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc tactacaagt
    60421 ctaaaacgaa atttaagact tttcctcata aaatactggt ttattttggt ctcatgtaaa
    60481 actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg tctttcattt
    60541 ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat aaactttgcg
    60601 taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt ccaagcattt
    60661 tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg aatccaagaa
    60721 tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg ctgaagtccg
    60781 caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg ataattcctt
    60841 gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg aacaacagat
    60901 tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg tctaatcctt
    60961 taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt tgtttgatga
    61021 tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg aaattttttg
    61081 cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta ccaactacaa
    61141 ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag tcttgagctg
    61201 tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg tgtgtaggat
    61261 acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca tacatttgga
    61321 tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag taaggtgctt
    61381 gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta gaaaacagat
    61441 agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc ccaaataatt
    61501 gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg gcaattccat
    61561 ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg atcgaaccat
    61621 aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac aaatacacgg
    61681 tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca tattctgttt
    61741 tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat ttgctcagct
    61801 acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc ttcatcagat
    61861 aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc ttgcggagag
    61921 tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag ttccaactct
    61981 gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag tacttgattt
    62041 cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt atccacgcta
    62101 ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag tttagagtga
    62161 ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg ttcatcgtaa
    62221 tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc acgtacttgt
    62281 cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata aactgtttcc
    62341 cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc aacatcgccg
    62401 acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga cgctagcgaa
    62461 ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt ttgttccggg
    62521 ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt atcttccttc
    62581 aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa ctgatcaaac
    62641 tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac cgcttgagaa
    62701 aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc gtttagccaa
    62761 tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag ctctgcaagt
    62821 tgcgcactta actttgtctg atccgaataa ttcaaactat ttgtttccaa catgctgctg
    62881 agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg gataaaaatc
    62941 cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc tgccaattga
    63001 tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt ttaatgggtc
    63061 aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca attcgccgtt
    63121 ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca aaagaaacag
    63181 acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta aagacaaata
    63241 aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc gtggagatgt
    63301 cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg taaaccaagt
    63361 ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca caggtacttc
    63421 tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg tcacatttgc
    63481 gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg tcttattctt
    63541 agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc aagtggaagt
    63601 ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc ttgccaaaca
    63661 agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata cttctaaata
    63721 ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt tttagattct
    63781 taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc caaatacaca
    63841 tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc ttgtgcgccg
    63901 atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc ttgaacaatc
    63961 tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc aaaatggata
    64021 ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt atcttgaaaa
    64081 aacgtatgcc aagcttctcc atcaatgtca tcaacttctt gataaggaca ctgttgttcc
    64141 acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt tgacaattct
    64201 tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt attcttagca
    64261 taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg tttgcttttt
    64321 aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct gaatagctgt
    64381 aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat actgaaggat
    64441 aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc tgagcaacca
    64501 acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct aaagttgttg
    64561 gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt caagtttacc
    64621 ataaaaaaaa aagaaatgca ataaaaataa ataagaagct cattaagatt tttctaaatt
    64681 attcctcatt ataaaatttc aagtgttttt ttattttgag ttttactctc ccgtaagcgc
    64741 tcattacttg cttgtgatcc attgctaaac attcagccat gtctacaaaa tcaacgcctt
    64801 gcatataata atgaaaaatt ttagcttcta tttttgaaaa ctggatttcg caattttcga
    64861 ttgcttcttt taataaaaga tgctgaattg ctaaaggttc ttgcaatgtg atctctgcta
    64921 aaaagtctgg tccttctgtc tctatttttt ggtcgattga gacttcatct ttttgatcac
    64981 gacgcttcag cgcgttctgc ttcctcaaca gagaatagat ttgattgctt ataacgcttt
    65041 tataataact tccaaagcta acacctttgc ttttttcgta agttctcaat gcctgatata
    65101 aagcgatcct tgcttcttgt tcccaatcct cagaaacata atttcttaaa taataggtgt
    65161 ttttcaaacg tagtaaaagt ggaaaatatt tttgatacag ggcagcaaat gcttcttcgt
    65221 caccattacg tgcagcgcgc aataactcct cagacataaa ataattcctc cataaattcg
    65281 tttatggagg aatcttatca tcaatgattc atcgaactga ttagaacgat atgttattta
    65341 ttttttctca ttaaatcgtc caatttttgg gacaattttt ttaactgctc ttcattccat
    65401 ggagaattac gtcggaaatc aataaaatgc atatctttat tttcttgggc tattgttttt
    65461 tccgtttttt ttatcgtctt atataattca taagcagaag ttcgtaatgc tccttgggaa
    65521 aagatcatcc actgttctgc taaatcgctt gtcgccactg tcacttgtgt caaacggtca
    65581 ttcagctgac cagcgattct ctcgatataa ctgtcagccg tttcgtcttc tttcgtaaaa
    65641 acaacatcca actggtattt cttataattt tgttggatgc ccggaactag ttgggcatcg
    65701 aagacaacga tgacttccat tccttcatat ttcgcataat ttgataaacg atgtaaaaga
    65761 gcttctcttg catccgccat tttgtcctgc tttttaagct ggacaagttc cggccacgaa
    65821 ccaatcatgt tgtagccgtc tacaatcaac agctgttttt tcatggtcta ctccccctga
    65881 cgttgggaaa aagcctgata cataagcaaa ccagcagcaa cactggcatt taagctctgg
    65941 acgtgcccgg tcatcgggat cgtcagcaat tcatccattt cttttttcaa tcctggactc
    66001 attcctttgc cttcattacc aatgactaaa gcaattgatc ctttggcatt ccatttttgg
    66061 aagtttgtgc cggtcatatc tgtgccaaat acccaaaatc ctgtttcttt gagctgttgc
    66121 acagcttgta ccaaattcgt cacgcgtgca acagggacat gttcgactgc cccagtggaa
    66181 gtctttgtta cgataggtgt gattccaact gctcggtgtt ttggtatgat cacaccatcg
    66241 acgccacttg cgtctgctgt ccgtaaaatc gacccaaaat tgtgtggatc ttcgatgcta
    66301 tccaaaatca aaaagaaggg gtcttctttt ttctcttttg ttcgttcaat cagttggtca
    66361 agggataaat attcataagg tgtaatcgca agaacgactc cttgatgcac gccgtgatcg
    66421 ctcaaagttt ctaatttttg tttaggaacc catttgactg gcacagcttg ttcacgtgcg
    66481 atttctttca gttcttctac tttttctcct cgtgaatctt cttgaagaaa gagtttattc
    66541 cctcgccctt gttgtagcgc ttctactgcg gcatggtgcc caaagacgaa attatcttct
    66601 aatgcttctt cattttgatc agaaactgac tgatttcgtc cagtttgctt tttatttgaa
    66661 tatctatttt gttttttgtc ttcaaatcca cgtttcgatt gatgtttgtt tgttctttct
    66721 ttacccattt ttttcaccaa ctttctgaat acaccagcgg atcaattctt ccatccgctc
    66781 ggtttgtttt gtcaaatgca gatagcccat gagcgcttcg aaccctgttg cgacccgata
    66841 cgtcgtaaca tcagcatttt ttgcgctcgt atggctttta gcatttcttc ctctgcgata
    66901 ataaagttct tcttcttctg tcaaaagatg ttcttccagc atttgctgaa tcaaaaaggc
    66961 ttgtgcattc gcagaaacat aattcgttgc cgcacgatgc agcttattgg gttttgtttc
    67021 tccttgatca atcaggtggt cacgaacata gatttcgtaa atcgcatctc caacataagc
    67081 caaggctaaa ccgttcaatt gtgtgtaatc tctcatgctt ctcttctcca tcgggttcct
    67141 tgcggtgtat cttctaataa gatccctttt tctttcaaca aatcacgaat ttcgtcgctt
    67201 cggacaaaat cacgattgct tcttgcttga tttcgttctt cgatcaattg ttcaatctct
    67261 tcatctaata actcttctgc tgtaaataaa ataccgaaga tcgaaagcca ttgcgagaat
    67321 aaagcttctc cttgtgccaa gacagcggca gaaactttcg gctggtctag ataagtgttc
    67381 agccacttag caagctcata gaccactgtg atcccatttg ctgcattaaa atcatcgtcc
    67441 atttcttcga tgaatcgctg ttctaaattt tctaacaaag cgattttatc cgcatcatct
    67501 gccaaattct ctgaggcagt ttcttggcgg aatttcaaat tgtcaaacgt attcttcagt
    67561 cgttgtaaat tggtggctgc ttctttcatc gtcgtttcac tgtagcggat cggacgacgg
    67621 tattgtgtgg tcgccatgaa gaaacgcaag acttgtggat caacgttttt gatcatttca
    67681 tgtacagtga tgaaattccc tagagattta ctcatttttt catcgtcttc gccaatcgtt
    67741 acatagccat tgtgcatcca gtaattagcg aattttttcc ctgttttcgc ttcactttgt
    67801 gcgatttcat tttcatgatg aggaaattct aaatcttgcc cgccaccatg gatatcgatc
    67861 gtttctccta aatgttttgt tgccataacg gaacattcaa tatgccaacc gggacgtcct
    67921 ttgccccatg gtgaatccca agaaatctcg ccaggttttg cttgtttcca taaagcgaaa
    67981 tctaatgggt cttctttttg ctgctgttct tcccctgtac gctgacttgc tccgacttcc
    68041 agttcatcga tggattggtc acttaatttc ccataatttt caaatttacg ggtacggtaa
    68101 tacacatcac ctgaagattc ataagcatag cctttttcaa ccaacacttg aataaatgct
    68161 aaaatatctg gcatatgatc catgactctt ggatgcagtg tagcaggttc gacattcaac
    68221 gctttcgtat cttcttcaaa tgctcggatg aaacgatcag caacttctgg tgctgtaata
    68281 cctaattcgt ttgctgtacg gatgatttta tcgtctacat ccgtgaaatt cgatacgaaa
    68341 tcgactttat agcctcgata ttcaaaatag cgtcgaattg tatcgaaagc aatggtgcta
    68401 cgagcatttc cgatatggat ataattatac acagtcggtc cgcagacata cataccgaca
    68461 tgtccctttt gtatagggat gaattcttct ttttttctgg tcaatgtatt gtagattttt
    68521 atcattctga tctcctcact ttttctcctt tgattcgaac gacttttgct ggtactccta
    68581 ccgctgtagc gtcgtctgga acatctttca acacaacggc acctgcaccg attttggcgt
    68641 tttttccgat cgttaccggt cctaatatct gcgcattcgc agagagcatg gctccttgtt
    68701 taacagttgg gtgtctttta cccgtttctt ttcctgtgcc gcctaatgtt acgccatgga
    68761 ataaaatcac atcgtcctcg atttctgcgg tttcgccaat gacgattccc attccatggt
    68821 cgatgaacac gccagttcca atcgttgctc ctggatggat ctcaacacca gttaggaaac
    68881 gccagaattg agcattgatc ttcgccaata aaaagagccg gtgctgatat aaaaaatgag
    68941 agaaacgatg ccaaaacaag gcatgaaaac cagggtatgt caaaacgatc tcagctgtcg
    69001 aacgtgcagc cggatcgttt ctctttgctg catcaatcgc tcgggtaaac caactcatga
    69061 ctttccactc ctttcgtaag aattttatgt aggaaatcat cttcttataa agaaaagaag
    69121 cgccttttaa ataagtttcc ttatcaaaag acgctttccg cgtggttcca cttttcttca
    69181 taatcaatga ttatctctga cagctaacgc ctgttatacg ttcttggcta ctttgtttcc
    69241 tataaaacag tttttcctgt tttctgtgtt tcgccaagac cactcccaga ggcatttcgg
    69301 caaccattca ttgatacctt gcaccacccg gtatctctct tgtaatgatc agctgcttac
    69361 ttttttctgt tcatcgtgtt tagttcagta cttgatttaa atgtgctaat gatttttcac
    69421 gaccaagcaa ttcgatcgtt tcaggcaatt ctggaccatg catttgtcct gatacagcta
    69481 cacggattgg catgaaaaga ttttttcctt ttacgccagt ttctttttga acagctttga
    69541 tggcagcttt gacagttgga gcatctacta cttccatttg ttctagctgt gctttgaatg
    69601 cgtggagaac agtaggaact gtttcaccag caagtacttc ttttgctgct tcattcaata
    69661 caggatgttc attgaaaaat agcgtagaca gatcaacgat ttctgcagca tagctcattt
    69721 gaggttgata caggctaacg atcttcttca cccattcgat tgtcttttca tctgggtttt
    69781 ctgctacacg tccatcagcg attagataag gcagacacat gtcagtaaat gcatctagat
    69841 ccattgcttt gatgtaatgg ttgtttaccc attgcagttt tttcgcatcg aaagctgcgg
    69901 gtgatttact taggcgtttt ggatcgaaca ttttgatcaa ttcttggtgt tcgaagattt
    69961 cgtcttcgcc cacaggtgac cagcccaata atgcaataaa gttgaacatt gcatctggta
    70021 gatagcctaa ttcgcgatat tgttcgataa attgcaagat tgattcgtca cgtttgctta
    70081 gttttttacc tgtttcactg ttgatgatca atgtcatatg tccgaaggtt ggtggtgtcc
    70141 agccaaatgc ttcatagatc atcagttgtt ttggtgtatt ggcaatatgg tcatctccac
    70201 gtaaaacgtg agtgattttc atcaaatgat catcgaccgc aacagcaaaa ttataagttg
    70261 gcataccatc gcgtttttgg atgacaaagt cgccaccgat attatcggat tcgaacgaaa
    70321 tagcgccttt caccatatct gtaaatgcgt attctgtatt gcgaggcaca cggaaacgta
    70381 caacagattc tagaccttgt gcttcttttt ctgcttgttc ttcaggtgtc aagttcgcac
    70441 atgttcctgc gtaatgaggc atttctcctc ttgcgcgttg tgcttcccgt tctgcttcta
    70501 attcttcttc tgtgcaatag catttgtatg ctcgattgct agcaagcagc tgatcaatca
    70561 gcggttgata gatttcttta cgttcagatt gacggtaagg gccgtattct ccaggatttt
    70621 caggagattc atcccaattc attcccaacc aagcaaggtt ttccaactgg cttttttcgc
    70681 catcttcgat attacgtttt tggtcagtat cctcaatacg aataataaag tctccatcat
    70741 tgtggcgggc aaacaaataa ttgaataatg cagttcttgc atttccaata tgcaggtgcc
    70801 cagttggact tggtgcatag cgtacgcgta ctttcgtcat tttcttcctc ttctttcaaa
    70861 ctagactttg actaacagca aaaattccgt cagttacggc ttctcaaata tcatttattt
    70921 aaagccactc agcacaaatt ttaccttttc taaggtaaat agtaaagcca actggttgaa
    70981 tttccttacc agttggctga atttcttttt tattttgatt gtttagtctt tttctctgtc
    71041 tcttttttat tgtcgattcc tcgtcctgca tgtgcaggtt tagcaaagat catgcgtcca
    71101 gcagctgttt gaagggcact tgttacaacg acttcgatac gttcattcat gtaatgctgt
    71161 ccatcttcta cgacaaccat cgtgccgtca tcaaggtagg ctactccttg ttggcgttct
    71221 gtcccggctt ttactactag aacattcatc gtttcaccag ggatgacgac tggttttacg
    71281 gcatttgcca acgcattgat attaagaaca ggtacatttt ggaattcaga gactttattc
    71341 aagttatagt cattggttac aatgacacca tctaaaagct tagccaattt gatcaatttg
    71401 ctgtctactt cactgatatc ttcaaagtct ccatcgtaca tttcgacaga tataccctct
    71461 tctttttgca aggcatttag gatatctaat ccgcgacgac cacgcacacg tttcaaacta
    71521 tcccctgagt ccgcgatgta ttgtagttcg taaagaacaa aattagggat catcaaggtt
    71581 ccttctaaga atccagtctt tgtaatatca taaatccgac cgtcaatgat cacgcttgta
    71641 tccaagattt tatatttatg gaaattttct cctgattttc gttctaacag ttgactctca
    71701 acttgactag ctgtttcttg ctcgattttt ttgcttcgtg aaccaaaaac tttcttccat
    71761 tcttcgattc gtgtcgttcc cattctcaat cccagatagc ctaagatgat catcagtaaa
    71821 atcggcaata cactattgac gaatggaatt tccatattgt aaagaggggt cgagatcaca
    71881 acacctaaag tcaatccgat gatcgcaccg atcgcaccga agagaagata agtcaagctg
    71941 acctcactta gtttttgttc tacttgtttg ataatagctg agatatgttt ggccaacagc
    72001 aaagataata aaaagaaaat aagtgcgcct aacaggctgt tggtaaatgt attattcagc
    72061 catccgtttg actgttgacc gattgcctgc caagctgagg gtaaaaatga aatacccaag
    72121 cttgcgccga caatgatcat cagcaaagta atgacacgtt tttgcatcgt ttttcctccg
    72181 tttcgacaat catttattag ttagcggaac acacgcttca acgtttcagc caaagttgct
    72241 actccaacta tctcgattcc ttttggcgct tcccagttac ctaagttgtt tttaggtagg
    72301 tatacttttg tgaagccgag tttttggact tctttgactc gttgttcaat atgactgaca
    72361 cgtctgattt ctccagtcag tccaatttca ccgatgaaac attccgttgg ctgtgttcct
    72421 ttttctttat agcttgaagc aatactgaca gcgatagcta aatcaatcgc tggttcattt
    72481 aattttaccc cacctgcagc ttttaagtaa gcatcttgat tctgaagaag caacccagct
    72541 cttttttcca gcactgccat gatcagagat acccgattga aatcaagacc tgttgttgtt
    72601 cgtttggcat ttccgaacat agtaggtgtg actaatgctt ggatctctac caaaattgga
    72661 cgtgtccctt ccattgccac aacgatagca gagccagttg caccgtctag gcgttcttct
    72721 aagaaaatct gtgaaggatt agcgacttct tccaatccat gctcatgcat ttcaaaaatc
    72781 ccaatctcat tcgttgagcc aaatcggttt tttactgctc gcaaaatccg aaaactatga
    72841 tgttgttcac cttcaaaata taacaccgta tccaccatat gttctaacat tcttgggccg
    72901 gcgatcgagc cttctttggt aacatgaccg acgataaaaa tggctatccc atttgtttta
    72961 gcggttttga gtagttctgc agtggtttct cttacttggc tgacacttcc tgccacactt
    73021 gtgatgtctg gctgcgtcat cgtttggatg gaatcaatga taacataatc aggggagata
    73081 tgttcgatgg cacgactgat ttcgttcata tctgtttcag cgtatagata aaattctgtg
    73141 ttgatacttc cgaggcgttc cgcgcgtaat tttatctgct ctgcgctttc ttcgccggat
    73201 acatataaga cttttccgcc tatggctgct aattgctgag aaacttgtaa cagcaaagtg
    73261 gatttcccga tacctggatc gccaccaatc aagaccatag accctggcac cacacctccg
    73321 cctaacacac ggttcagttc ttctaatttt gttttgatcc gaggttcttt tttagggacg
    73381 acgtctgcga tttttgttgg ttttgctttt tctcctgtca aacttgtccg agttctgcgg
    73441 tccgttgtat cttgttcgat ttcttcgacc atcgtattcc attttccgca atttgggcag
    73501 cgtcccaaga acttaggcga cacatacccg caattttggc aaacaaattg tacttttgat
    73561 ttttttgcca ttgtaccgcc tccttttatc ctaatcatga gacattaaat caagcttaag
    73621 tatctttaac gttttattta ctggaagaac caaatccgcc ttgacgttga gcagtcgttt
    73681 gatcttgatc tgcttttaaa aacggcaaaa agatcccttg gccgatacgc tcgccttttt
    73741 tgatcactac atccttgaaa ccaaagttgg tgaattggaa catgatatgg ccttcatttg
    73801 cctcattatt gtaataatca ctgtcaatca cacctactcc gtttgtcaac actaaaaacc
    73861 gcttcaacgg attgcttgaa cggttagcaa gctgcaaaaa ttcatcttct cccatgtaag
    73921 ctttgattcc agtaggcacg agggttggtt tcaattgttt ttcattttct gatacatctt
    73981 ttttcaatcc atctgcgact gtttccaacc cctttttcca gcctgctttc cagatacttg
    74041 gaatcacgac ctcttctgct gcttcaaaat catagccagc agcatgatgt gtagcgcgct
    74101 gcggtagatt gatattttga tctttatatt tagaaataac ttcaaatcct ctttttctca
    74161 ccggttttcc tccctaaata aactactcct attctaacat atccgaggct gtaaaagact
    74221 ttctttacaa attcttcaag aaattctgct atcttaaagt aaaccattaa ttcgttcttt
    74281 ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta catgacttta ctcgtcaaaa
    74341 caagtagaat agaacgaaat taatgagtgg atatttgatt gaggtgtcac atgcgtaaag
    74401 aaattaaaaa tgcaaaacga attattgtca aagtaggaac aagtacattg atttatccca
    74461 atggaaatat caatcttgcg gcaatcgatc agttagcttt tgtcctttct gatcttagaa
    74521 atcggggaaa ggaagtgatc ttagtctcat caggagctgt aggcgttggt atgcataaat
    74581 tacatttgtc agaacgtccg actttgattc ctgaacagca agctgcggcg gctgttggtc
    74641 aagccgaact gatgaatatc tataatcaaa gattcagtgt atataatcaa cagacggcac
    74701 agatcctcgt gacaagagac gtggtagatt atcctgaaag tcgtaaaaat gtgaggaata
    74761 cattggaaca gcttttgatt atggacacga tccctatcgt gaacgaaaac gatactgtag
    74821 cagtggatga attagatcat ctgacaaaat ttggcgataa tgatcagctg tcagccatca
    74881 tggcaaaact tgtcgcggca gaccttttga tcgtcctttc tgatatcgac gggttttatt
    74941 cagataatcc gactacaaat cccgaggctc agatgtatcg ctatatcgat aaaatcgatg
    75001 aaaagattct ggcacaagca ggtggtgctg gtagcacatt tggaacaggc ggtatgcaga
    75061 gtaaattaaa agccgcttct aggatatttg aagcaaacag cgcaatgatt ttagcaaatg
    75121 gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa agaagtaggt actttattta
    75181 aggaggactt gaaatgactg acttgatgca attaggacaa caggcaaaag atagcgcgca
    75241 acaactagca cttatgccta caaaccgcaa aaatgagcta cttgttcaaa tggcacaaac
    75301 catcaaaaag aatcaacaag cgatcattga agcaaatcat aaagacttag aaaaagcagt
    75361 cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag ctgacacctg agcgaatcaa
    75421 tgccatggct acagagatcg aaaaaattgc ttcgttagac gatcctattg gaaaagtaga
    75481 tgagatgtgg acgaacaccg acggattgag aatcggcaaa aagcgcgtgc cactaggcgt
    75541 gatcggcatc atttacgaat ctcgtccaaa tgtcacgaca gatgcagcta gtctagcatt
    75601 caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa gcattcttct cgaatcaatt
    75661 attagtccaa ttattgcagc aagtactggt cagtgctggc gaatctcctt atgccatcca
    75721 gtttgtcgat gatacttctc atgaaactgc aggacagttg atgcgattga cagaatactt
    75781 agatgtgctg attcctcgag gcggagcaaa attaatccaa cgagtcaaag aacaggcaac
    75841 ggtacctatc attgaaacag gtacaggaaa taatcacgta tatatcgata aagaagcaca
    75901 gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct tcccgtccat ctgtctgtaa
    75961 cgcggcagaa acattgctga tccattctga gatcgcacct tttttcttgc cagctattga
    76021 aaaagaactg gtagaacacg gggtctcttt acgtgcggat gctcgtgcgt tagaatatct
    76081 agagacggct gctttagcag aagacacaga ttgggatact gaatatctag attatatcct
    76141 tgctgtcaaa gtggtcgatt ctttggatga agcaattgca catatcaatc ggcataatac
    76201 taaacattca gaaacgatcg tgacagatag ttatgcggct agtcaacgtt tcttaaatga
    76261 agtggacgcg gcggctgtct atgtcaatgc ctccactcgt tttacagacg gatcggtatt
    76321 tggttttggt gcagagattg gtatctctac tcaaaagttg catgcccgtg gtccaatggg
    76381 gttaaatgaa ttaacttcca caaaatatat catttatggc gatggacaaa tccgcgaata
    76441 atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt tctgtaaagg ttctatccaa
    76501 ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt tttatttacc ttatttctct
    76561 gaatatcgct gcttttctgg gagtcggtat tttatccctt ttctttcaat tcaaaaaacg
    76621 aagcataggg agtcaacggg aaaaatggtc gcagtatttt gacaaaatcg ggcaaaaagg
    76681 gctggttaca cgcttgcaca ttagttacat ggttgcatta tgcttattag cgacaatcaa
    76741 ttactattct tttttcgatc attcaatcgc ttatacgatt acgctactga ttgctgggat
    76801 ttttcactta tcttataaat atcagctgaa taaaaaccac ttgaatcgga ctttccgcta
    76861 aaaaatatcc gtacgataag tagagtgcct tgaagatcgg caaaaaactg ccggactttt
    76921 tagaggctgt gacaaagatt ttgtcacagc ctctttttcc atataaacgg cgttcgccta
    76981 ccagctgcct ggtaaatctg tttcctcttc gttaagaagc gaaaatccgt caaatgtttc
    77041 gccatcataa taacgaagca gctcatccat ggacaagttc atcgtttttt ctttttcttc
    77101 ttccgctgat tcagccagta gctgttcccg atacacctga tacataccag ctattttttg
    77161 ctgcatcgct tttctagttt caccttccgc attgattatt ggcaattctt tgatatagcc
    77221 acgataaatc aaccgatcat ctgaaaattc aatgggtaat tcaacgagtg tcaacccgac
    77281 ttcctgaaaa tattcttcca gcatctatta tccccccatt ctttttctta aatgaatttt
    77341 agcttaccta ctgaaaattt tccagtttca ttattttgag aaaaaaaggg aatgtgacaa
    77401 aaatcgtgtc acatcccctt tttccgaata aatggtgttc ttctgccaac tcctcaatca
    77461 taagtcacaa tattcaacaa acatgagaaa ctgttttttg aaattgttcc ttgtgattca
    77521 gagttaaacg acagtctcac aacctcttgg taaacggcgt tcaatcagct gaccctcggt
    77581 attagctcaa aaaacggtaa aatatgagaa gctatttttc cgttttgttt ctctaatact
    77641 taggataaaa cgctgatttt acaacctctg ttaaacggtg ttcaatcagc tgtccttcgg
    77701 tattagctca aaaaacggca aaatatgagg aactattttt ccgtttgttt ctctaatact
    77761 caggacaaaa cgctgatttt acaacctcct gataaacggt gttcaaaagc ttgcatctgc
    77821 ggtaataagc ccaaccaaac gaaaaatatg agaagctatt tttgtttggc tgttcttatg
    77881 acttgatgca ggacagcttt ttcacaacct ctgatttctt attcttcttc atttgtagca
    77941 aaataattac ggtgataaat gatacaacat acactgataa gaacaatggc acctgcaaaa
    78001 taaaacgcat agctttcacc aatatgttca ccaatcacac ctgcaataaa tggtgctaaa
    78061 gctccaccga aaaagcggac aaaactatag ctggacgaag caacgtttcg ttgcagacct
    78121 ggtatttcca tagcaatcgt cgtcaacagt gtattgataa ttccttggaa aaatcctgct
    78181 aacacaatgc tgatcggtac aaggactggc atagaagttc cagctcctaa taacagcaaa
    78241 caaataatga ataagacaaa tgctgctaaa attgtccgat aagtcgtaaa cttccgctca
    78301 agagccggtg caacgaaaat cgaagcaata gccagaagca caccccagcc aaaaaataca
    78361 aaaccgactt ctaattcaga atagccaatc aataaaaatg gcgcatacgc aagtaaagta
    78421 aagaatccga aattatataa caatgcgatt agtccaactg aacgaagttt atgattgctt
    78481 aacgctttga caccttccca aaggcctact tttctctttg gtttctcagt ttcaggtaaa
    78541 agtaccgcta gggctataaa accgcaaaac atcaaaaatg ctaccccaaa aaatggataa
    78601 cgccatgaac cactgcccaa gaccccaccg actagagggc caacagccat tccgcagcca
    78661 agtgctgctt catacatcat gattgctttt tctgtgttac caactaaaat actgacgatc
    78721 gttgctaaag cagtagagac aaataaagca ttcccgacac cccagccggc acgtaaccca
    78781 atcagcattc cgatattccc agataatccg ccaagaccag cgaatacaac gatgataaac
    78841 aatcctgtca tcaatgtttt tttcaaaccg atccgactag ataagaaacc tgtaaatagc
    78901 atcaccacac cagtgactaa catgtaacta gtaaataaca gggtcgtttc agctggcgta
    78961 gcgtttaact gtgcagcaat cgtttttaag attgggtcta ctagacccac tcccataaaa
    79021 gcgatcatac aggtagctgc tacaactagc gctgaacttt tcccctttgt ttcttcattt
    79081 gtttgttctt gtatatctat ttgattctcc aatatttcca tccctttctc tctattagca
    79141 tcatacatga tttattttac atgtcaatat gcacatgtaa aacgtggaaa ctttactgtg
    79201 atataataaa gaaaataaga cgagaggtag gatttttatg aatactttag cctatatatt
    79261 attatgcgtg cttttatcca aaccacgttc tgggtatgaa ttgaagcagc tgatcacaat
    79321 tttttgggaa gcccatcaca gtcagatcta tacaacgctt gccaagttag accagcaggg
    79381 ttatgtgacc gttttggaca aagacgagca ctctcaaaaa aagatctacc acttgactga
    79441 tgaaggacgt gctcttgtag aggaatggat caaagaggaa actcccgctc ctacgcaaaa
    79501 agatgaattt ctagcaaaaa tctatgcttt ttcgacgctc gataaaacaa cagctactgg
    79561 actgctattc actagagaac aacagctgaa caaaatcatg caaaaaaatc aaaaaaaatt
    79621 gaatgacctc tcgctagaca agaaacaaga atttggacgt tatgttgtga tccagcgcag
    79681 aattatgctt tgtcagcagg aactccaatg gtgtcagcaa gtaagagaac aaatgcagca
    79741 gttttttgag taagggataa acagaacctt tctagaaata tctattgaag agcaaattat
    79801 cttcaataaa agagcaatac agttggaaaa gaaaaagcga tccgaacgac aggccaaaac
    79861 ctatcgttcg gatcactatt tttctagaac tgcattcaag agactatgac aaaaagcatg
    79921 ccaaggcctt ttttcaaata acagtgttcc atcattcatt actttgaatt gcttttagca
    79981 cacttcttga aagcgggcca acgatgatca actgcaacgg taaagcggca atcacattca
    80041 ttttccaagc attcatataa gcagagaata attgatcagg tattccttgt tccatgatca
    80101 caccgaataa agacatacat gtcaccattc ctaaaaccat caagcatgaa atagttaaga
    80161 tcatttggac cttgctttct ggatttactg gtagtttaaa ggcaattttt ttcgccagca
    80221 caccgatgat gaagacatcc aaaatgaaag ccaccacgaa tccaggcact agaccaatca
    80281 acaaacttga taaatgaaga tcttgatgca gccataaatt atacgcgctc atccccaaga
    80341 ccatcaaaaa acacatcatt gttgtaaaaa ttattccttc ttttttattt gtaggcaatc
    80401 tgtaccactc ctttaaattt gtcacgaaaa tcatcgtagc acatttaaaa atttctcgta
    80461 agtacttttt ttattttctg cccttttatt tcataaactt catcagccgt acgctcgaca
    80521 aagtaagaat catgagaagt aaacaaaatc gttcccggat atatttgcat tagcttctct
    80581 aaagcttcga tcgttgccat atcaataaaa ttagtcggtt catctaacag caacacatta
    80641 cttggcttag taaaaagcaa agcaatcgtc agacgggtcg cttctccccc acttaatgta
    80701 cataacggtt tcgtcaaagt ttcctgagca aaccctaagt gattcagcaa actacggaca
    80761 agcgattctg aaaactctgt ttgtctcatg acaaaacgaa tgatggattc ttcagatgtc
    80821 atttgataac ccttttgctg atatacttga aagcttactt tcggagagag aaggattcct
    80881 tctccttgtt tgcggatatg ttctaataag gttgtcttac ctgaaccatt ttcaccgaca
    80941 atcgcgattt ttttacctaa agaaaactga aaatcaccat ttaccagtaa tgttctccca
    81001 cttctttcca attggacatt ttgtcccatg atgggatagc ggctgtggag ttcaagagat
    81061 tttggtactg gaaaacggat ttgtttcatc tgctgcggct tggttgtttc tcctattttt
    81121 tggagtcttc tctctaatgt tttcgcattc ttttggatgg ctttttgtac actgtctttt
    81181 tgtttagagg aagacaaccg atccagtctg atttgttgct ttttcttttt actggacact
    81241 ttttccaact tttccgcttg ttttttcttt tcttggatcg atttttccaa tcgttttttc
    81301 tctttcatga tcgactctgc ttctcgtagc tgagtctttt tctccaattc cttttgagtg
    81361 agataggcac tataattccc cgaaaactct cggatttctc cgtcttttac ttcccagatt
    81421 ttcgatgcta gctcatctag aaaatagcga tcatgactaa caaaaaccag cgtaccataa
    81481 taataacgaa gctcttcaat cagtcgatca atactttttc tatctagatg ggttgttggc
    81541 tcgtctagaa gcatcccttg ttcataagaa gaaagaagac gtatcaactc gatctttcgt
    81601 tcttcccctc cgctccattt ccgctctgaa gtttcttcca gtcttaactg gaaatgactg
    81661 gctaattcca aatttaggtc ctttgcttca gcgagatagg ttaattgagg caggtagttg
    81721 aaggtgatct ctgtttggat tttcccatga tcgggaaaaa gttcaccggc tattagtttg
    81781 agcaaagtcg atttaccgac accattttct cctatgatcc ctatacgatc ttgctgatag
    81841 acacgaagag aatcaataga tagttctagc tggttgccaa agctgacttg tagatttgtt
    81901 atatttactg ctaaattttc catatgtttt acactcctat ttcatgtaaa acaacaatta
    81961 tcgatactaa aaaagagcag aaaaatctgt ttgcaaaaaa actgcatcac atcttttcct
    82021 actctgaacg aaataactat gactaaatca ccaaatctgt catagctttc acctattcta
    82081 ctgtcgttcg aaaaaatgga catactccat ccatgaaatt gttgtttata catgtctttt
    82141 gaatttattt agttgttatt caaaagttcg aaacgtaatt tcatcgatgc agtcattttt
    82201 ccgacctcct tttttattag gttaccacac acgattcaaa aaaagcaata gctactgaat
    82261 agtaactgaa aaccttttat tcgaacatag tgatcttttc tggtgctaaa cgaacagact
    82321 cgtaaccttc ttctaccgct tttcctattg ataaaataat aactggaaca taacggtctt
    82381 tatccaaacc aaatgcctct gccaactgat ctgcttcgaa tccaccaatt ggatttgttt
    82441 catagccatg atcacgcgca actaacatga attgcatagc cgctaagcta gaatcgactt
    82501 tgactacatc gttcatttct tctcttgaaa aactcttgta ataaggaatg atcgcagcta
    82561 attgttgatc tctgacttct tttggcatct tccctgattc gtaagcttgg ttgtagattt
    82621 cttcgccata ttcgtaacat tgcatatcgc caaaaatcat gaccattgca gaagaagtat
    82681 cattttgtct cgtattgaaa cggatcaaag gacgcaagat ttcttttgct tcctcgcttt
    82741 cagcgaccac aaagcgccat ggtttcatat tgacagaaga aggtgcagtc gtcgcttctt
    82801 tgatcatttc cagcatttct tcgtgtggga ttttgtatgt ttcatcatat acgcgaacgg
    82861 atcttctacc agtcataatt gttgaaaaat catttttttg ttccattatt attaacctct
    82921 ttcgtttctg ttgttatatt gcaaagttgg gtattcaatt tatctaaaag tgttagaaat
    82981 tgtttcattt ctacatcgct gaaagccggg gatagcacgg aacctgtatc tttatggtcc
    83041 atttcacaat gcttgatttt cttctgggct ttttctgtta gcgctacata cacttcccgg
    83101 ttgttctgag gatttctctg acgcgaaaca tagccatttg cttccaatac cttcagatga
    83161 cgagtaactg ctccttgatc aatctgcaac ttttcttgca aactgctttg tagcaatgga
    83221 ttttcttctt tcagtctcat catgatctcg tatctagtaa gacttatacc gatattttct
    83281 tcaaagatct ggacgatttt ttgatcggct aatttgattt gatataaaag gtgactaatc
    83341 tcttctaaag acataatttc ctcctttcta ataattgact cgtcaacgat tgacttgtca
    83401 ataatagaat aaaaaaagaa aaaagtcaaa gaatcagctg tgtaataaaa aaaacgctct
    83461 caatagaaaa gtatagagaa aagaaatttt ttgtagaatg aacggaaaaa atgataaaga
    83521 aagcacaacg ctaaaaccaa gattattgat tcttatcaaa ctatagaaga tagctcttct
    83581 gcagtagata attttacacc gccaaaaatt tccgaaatcg ccttttgcaa gaatcccgtc
    83641 gaatattaga aattggatca gtatgcttaa acagtaataa aaaagttatg acaagatgtt
    83701 gtcacaacct tttttgagta aacggtgttc aaaaacttgc atctgcggta ataagttcaa
    83761 ccaaacaaaa aacatgaaaa tctgtttttg tttggctgtt cttactactt gatgcagggc
    83821 agctttttca ctacctcttt ttaataacca taaaatccta ttccttcata tctccagccc
    83881 atcggtgtta gccaatctct ttccttagca ctcaaggtat agtgatgggt accagttttt
    83941 tcatttggat taaatagtcg ataaattggc ttggaaccac cagaataaaa acttagacct
    84001 tcataacgcc aaccgatttt tgttaaagag ttgatctcag attgtgccat tgtgtaatga
    84061 tggtctccac tgtaaggatt gtataaacgg tagacaggtt gtccgctgtt tggtgcttgc
    84121 caagcaatcc cttcatattc ccagcctaca gttggcagat aatttttttc tccggcattc
    84181 aatgtatata aatgttctcc tgtatgacgg ttatacagac gatacatcgg agaagttgaa
    84241 gttggtgctg tatcatactg tgtcagatta taggtttcga ttacattgtt caatgtagaa
    84301 ccataattag gcgcagtggc ataacgacct gttagccaag ccgtagcatc tttgtaagag
    84361 ttcgtattgc ttttccatgc accggaatag tagtaaacgc ctggctgaaa agaagtcgtc
    84421 ttcaataccg ttacgttatc ttgcaatgat tctttgtacg aaggatattt tctaaaagcg
    84481 gcattcaccg taatccattg cccattcaca tattccgaag taggcatcgt aacagattgg
    84541 ccattatagc ttcctttaat cccaaataga ttgtaattag gggcagaagc caaagtactg
    84601 ttcccccagc cactttcaac gatggcttga gcaatcatga ctgatgcata taagtcattg
    84661 gcacttgcca aactttgtgc agttgaggca atactatcaa tgaacgcttg ttgagaatta
    84721 gcagatgagc gagcataaaa agcatagcca gtatagtttt cgaattcaga caaatctgct
    84781 tgatgggtat gtgtcaatgt ttgcccatct gtcaattggt tcgtgatttc ttctgcattc
    84841 tctggattgt tctgagcttc tgctgatgta ctgtcttcgg tttgtgtttg ttctgttgtt
    84901 tcagttgttg gttcttcggt tgaaattgta ttttctgaga cagtagctga ctgcaaagta
    84961 ctttctgtat cgttttcaat tcctgtttct gaagaactcg atgtctgagt tgcgacagtt
    85021 tctgtcgatt cttcagctag cactgttgtg ttggcaactg ctagatttcc taaaagaata
    85081 acgctaaata ataaattctt tgctttcatc ttttttctcc tttgaattat gaaacttttc
    85141 ctaaataaca gtgtaactaa aaaagtaaaa gcaagtcaat gtccatattt aaataacatt
    85201 tgtttctttt taataaattt gctttttctg cataaaaaga cgtaaatgaa gaatattctt
    85261 ctccattcac gccttaaatt gatggtcgtt tgaataacta tttaacaagt aattctctct
    85321 ggatattatc cgttatggat tatacttcct gtgtcgtcgg acggataatc atgttgctga
    85381 cagacatccg gtctggcgtt tctatcgcaa atgctacagc agaagctata tcttcagatg
    85441 ttaatcccca ttctttttgc gcttcatgaa gttcaagagc agcctttttg tcgctgatgg
    85501 tttgatataa ttcagtttga acagctcctg gagagatgat cgtagatttg atgttatttt
    85561 gccgttgctc ttgacgtaat ccttccatga ttgcacggac agcaaatttt gttccgcaat
    85621 aaacggcgga atcaggataa acaacatgtc ccgccacaga atcagttgaa atgatatgcc
    85681 cagatttttg tttttccatg attggaagta cggcggaaat tccatttaac acacccatga
    85741 tgttgatatc aagcatattt tgccattcat cacggtgacc ttcaactaat ggagcggttg
    85801 gcatgattcc tgcattattg tacaatacat cgattcgacc gaacttttcc atcgctaaat
    85861 cgataactgc ttggacttgt gcaaaatctc ttacatctgc tgtttgaata tatagctcag
    85921 cttctggtaa agattctttt attgctttta ggcgatcttc tcggcgtgca gctataacta
    85981 gtttagcccc tttttctgct aatagcttcg ttgttgcttc accgattccg cttgaagcgc
    86041 ccatgatgac aatcactttt tctgataaat cattcattct attctcctcc tgttttgaaa
    86101 aatctcttgc ttatactcac tatctcttat ttcatcttac tgttcaaata atccgttcga
    86161 caggtttgac gattttggca gggattcctg caacgatggt attgtctggg acatctttcg
    86221 taacagttgc attcgctgca acaatggcat tctcgccaat cgttacgcct ggcagaatag
    86281 ttgctcctgc tccgatccaa gcatttttct tgatgtggat tggctttact gacaagcctc
    86341 ttcgttcttt tggatcggtt agatggttca ccgtgatgag gttgacacga ggaccaatca
    86401 atactgaatc ttctaaacag atgccaccta agtcaacgaa catcacttga cgattgataa
    86461 agacattttt ccctatacta atatgtttgc cgaaatctgt ataaaaaggc agcagaacag
    86521 tcaccgtatc atctactttg tcactaatga tattttctag ccgtttgcgg atatctgctg
    86581 gttcatggta cccagtattc agcgctgcta aaggctcttc gttttccgct tggatctgat
    86641 ggatcacttc aaagagcgga tccgttactc gaatctcttt attgacgatt tgtttttcga
    86701 tgaggcttgt cattttgctc cctcctttta tccttacttt ataacggacg gcttatgatg
    86761 tctaatactt ataaaacata cttaactatt ccttttaact atacttagtg gtatgctttt
    86821 ttaaaaacag gagggaaaaa atggatattc gtatactgac gtatttttta gcagtagcta
    86881 gagaaaaaaa tatcagccga gcagcaaaat ctctgcatat cacgcaacct actctctcaa
    86941 aacaactgaa agatttagaa gaagaacttg gtgtgacact tttcactcga ggctcccgag
    87001 agatacagtt gacggattct ggtcgatatc tttattcaaa aggaaaagaa atcttgtcgt
    87061 tggtagaaaa aacggcgaac aatttaacaa atgacgcaat catctctgga gaaatctaca
    87121 ttggcggagg cgaaactaaa gcaatctctt tcatttctga tagccttcat tcgttgatca
    87181 aggcgcatcc tgatatccag tttcatttat atagcgggaa tgcagatgat atcatagaca
    87241 aactggatag cggattactt gattttggac tcgtaatcga accgacaaac aaacaaaaat
    87301 accagtcatt tcgactgcca gcccaagatc gttggggact tttgatacat cggaatcatc
    87361 ctttagcaaa gcaaacagtc atccatccgc aggaactgaa aactgttcct ttgatcattt
    87421 cccggcaaac gtcagtggac agtcaactag ctgaatggct aggtttcagc atagatcagt
    87481 tatcgatcgt cggaacatat aacttattgt acaatgcttc tttgatggtc gataacggga
    87541 cttttggtgc attagctcta gatgggatca tcaatactta tgggacggaa aaagtattca
    87601 tcccactcga tccgccatta caagcttcac tgaatctcat ttggaaaaaa gaccagcctc
    87661 tttctcctgc tgctcgtaaa tttttagatg tcctaacgga gaaatacagt taagtagagt
    87721 ttttttcctt cgctttcagc tttttaacaa cgaataagtt aagcaaaaga tccaatgatt
    87781 aaataacata agtttcttaa tttgttcctt ccttttattt ctgataattc cagtaaatta
    87841 ctataattat aaaaaaagaa ttgacaaaac ataactgtct atataaaatt gattacgtta
    87901 acaataattc gtttcatgtg actagatcat actaggcatg aaaaatctct gaggaacatg
    87961 gtttccctag gaggtttttc gtgtctattt ttgtttggcc gcaatcaact ggtctagcaa
    88021 acgtgaaaac caaatcttca aaaagggtgc gcgcatgaaa atcaaaaaga tctttaatca
    88081 aaatgcagta ttggtagatg acggtggaca ggaaaaagta gctattggaa aagggattgg
    88141 atttgacaga aaaagaaatg atttgatttt tgatcgtgat gtcgaacgga tatttgtcat
    88201 ggaaccagaa ggtcaaatca agttgcaaaa tttacttaat cagattgatg aacgcttttt
    88261 atttgcagca gaaacgatca ttgatcatgc ggaaactgtt ttgatggaaa agttgaatga
    88321 acatgtattg atcgctttga ccgaccacat tgctttttct gcggagaaca ttaataacgg
    88381 tatcgtcatc cgcaacaaac ttttaagaga aatcgaagtg ctttacagtg atgaattcag
    88441 tattgctcaa tgggcagtag agtatctgac aaaagagctt gggattccat atacttatga
    88501 cgaagcagga tatatcgcaa tccatattca cagcggacga agcggtcgga acaataacca
    88561 tcgcagtatc cgtgaagtga cgattgtatc tgacatcatc catttagtgg aatcagaatt
    88621 ggaaacagat atccattcag aaccattttc actgaattat tcaagactgg tgaatcattt
    88681 acgactgctt ctacaacgaa cccatgcgca acaatatgct gttttagaca cggaaatcgt
    88741 agaaatggtc aaacgaaaat acccagaaag ctataagatt tctaaaaaaa tccgtgtgtt
    88801 gctgaccaaa gaataccagc tcgcgatcac gaaagaagaa ctgggttact tggccatcca
    88861 tatcgagcgt ttaagaagcg caatcgtaca aacaaatgtt aacaatcatg aggaggaaaa
    88921 aaattgaaag catatctaca acgaatggga cgttcccttc aacttccagt tgcggtctta
    88981 cctgctgctg ctttactagt agggatcgga aactggtggg catcttatag taacgacatt
    89041 gtcgctcatt ttttacaagc tggcggtaac gcagttttag gtcaattacc tttgctgttt
    89101 gccgttgggt tagcactagg gatgtcagtg gacaaatcag gtgctgctgc cttggcaggt
    89161 ttggtcgcat ttgaagttcc agtaaatgtt ttaaaaactg attcagtagc tactttattg
    89221 aatatcaaac cagaatcagt tgatccatct tttgctcaga tcagtaacgt atttattggt
    89281 attattgccg gattgattgc ggcagctctt tataatcgtt tccacgaagc aaaattaccg
    89341 atggctttat ctttctttag cggcaagcgt ctagtgccaa tcttggctgc ctttgtcatg
    89401 ttgctgatca gtgcagtgct actgctcgta tggcctccgg tttactctgc tttagtttct
    89461 tttgctaaat tcattttgag tttaggctgg ggtggtgcag gtctttatgg cttcttcaac
    89521 cgtttactga tccctacagg attgcatcaa gcaatgaact ccgtgttctg gtttgacgta
    89581 gcaggaatca atgatattgg taaatttttg gcttctgaag gaacaaaagg cgtaacagga
    89641 atgtatcaag ctggattttt cccaatcatg atgttcgggc ttccagcagg agcatatgct
    89701 atttacagaa atgcacgtcc agaaaacaaa gcaaaaacag cttccttgat gttagcagca
    89761 gcttttgctt cattctttac tggtgtaaca gaaccacttg aattctcatt tatgttcgtt
    89821 gcttggccat tatatgtctt gcatgcaatt ttcactggga tttctttagc agtgagtgca
    89881 ttcttccatt ggacagcagg atttgccttt agtgccggat ttgtcgatta cttcctatct
    89941 ttgaaaaatc cgattgcgaa tcagccattg atgttgatcg tccaaggatt agtaacagca
    90001 gtgatttact actttggctt taactttgct atcaaaaaat tccatctgat gactcctggc
    90061 cgcgaggaag cagatctttc agatgacgat actgcaacga ctaattcaga caataaatat
    90121 gcggcacaag caagcaaaat ctacgctgca ttaggcggag ccgacaatgt aacttcgatc
    90181 gataactgta ctacacgcct tcgtttgcaa gtcaaagata caggcctgat cgatcaaaat
    90241 aaaatcaaag ccactggcgt acctggtatg aagatcatcg acggaaaaaa tgcgcaagtc
    90301 atcgtaggta cagaagtaca attcgttgca gatgagatgg caaaactaca tggtggtgct
    90361 gcaacacgac ctgcacaaac aaacaccgtg gttaaaacag aaacatttgc cggtggaacg
    90421 atcgaacaag atatttacgc tatcgcaaat gggaaactga ttccaatcac tgaagtttca
    90481 gatgatgtat tcgcggaaaa aatgatgggt gacggctatg ctgtattacc agaaaatgga
    90541 gaaatcttct ctccaatcgc tggtacgatc acaaacattt tcccaacgaa acatgctgtc
    90601 ggaatccaaa cagatgctgg tatcgaagtc ttgcttcata tgggcatcaa cactgttgac
    90661 ttaaaaggcg aaccattcac tttatatgta aaagaaggtc aaaaagtcgc aagaggtcaa
    90721 ttgattgctt tagttgatct tgccgctatt caatctgcag gcaaaaacac ggatatggtc
    90781 gttgtattca caaatggcga caaagtccaa agcttagaaa tcgaacccgc acgtgatgta
    90841 aaagcaaatg ataaaatcgg ctctgtttcc aacaaagcct gagccatcgt cttccccaga
    90901 cttttttatc gataaacaaa caggagctga gacaaaaatc ttgtctcagc tcctttttcc
    90961 gaataaaaac ggcgttctcc tgccaactcc gcggtaataa gtccagccaa acgtaacata
    91021 tgaagagcta ttttttattt gactcttctt attacttgat gcagaacagc ttttttacaa
    91081 cctctgataa acggtgttca aaaaccagtt tatcggtatg aagtcaaatt tatgcaaaaa
    91141 tgtggaaagc cattttcaca aaatttttct tcatactcaa aactaatcgg ctttttcaca
    91201 acctctttat acattattcc tgatccaata tttcttttaa tgctgcttca agagaagtta
    91261 atggttttcc caatactttt tctaaatcat cagaggaaat agctaactga tcctttttaa
    91321 tatcatgttg gatcgctaaa aacatgtcag ctgcttcttg agggaatccg gcttctttta
    91381 gattttcgac aaacgctgca tcacttgctt caataatttc taacttttta cctgtcgcac
    91441 gctctaatgc cttggctaat tcttcatagt cagttagatt gccggataat tctaagattt
    91501 ctggagagtc actttctact agtacttttg ctgcagcttc tgcatattca cgtttcaatg
    91561 cccaacctgt ttttccattt cctgcagcat aaacgaattg accagttttt aaagcctgcc
    91621 caatgatagg taattcattc tctacatacc aattattccg taaaaatgta tgggaaatac
    91681 ctgaatcctt aatcattttt tcagtgaatt ggtgatctgg cgctaataca ctgatcgagt
    91741 gatcggcatc tgcaaaactt gtataagcga tataagatac cccagctgct tgtgctgcct
    91801 tcactacatt cttatgttcg gcttgacgat ttcctggaac gccagagaca aaaagcaatc
    91861 gatctattcc tttcaacgct tctttcattg agtctaaatc atcataatca ccaatacgta
    91921 tattaaatcc agcttctttc agtgcttctc ctttttcttc actacgtact agtacataga
    91981 tttcattttg tggaaccatc ttttttaaga attccagcgc ataaccacca aaacctccag
    92041 ttgctcctgt tactaaataa tgcatatttg ccactcccta ttctttttat ttgttaagat
    92101 ttacagctgt acatttataa attacacctt tatcataaag agtgtggtaa gataagtcaa
    92161 gcaaaaaaaa tgaaaggatg acaactgatg aagtattctc tgcaatttag tgatgcaatc
    92221 catgtacttg cctatattga aatgtttcaa gatacccgat cactttctag tgagatgatt
    92281 gccagtagta tcgaaacaaa tgcagcaaat gtacgtaaaa tcatgagtca gctcaaaaaa
    92341 tccggtttga tctttacaaa aaccggaaaa ccgcagcctt cccttgccaa aagtccagat
    92401 cagatttctt tactagatgt ctatcgcagc atcgaaggta atacacagct tatccaagtc
    92461 gatccaaaaa caaatccaaa ttgcgtcgtt ggtgcgaata tccaagaagc tttagaagaa
    92521 agctacgctc ggctgcagaa aaaggcagaa gaagaaatgg ctaagatcac acttgatagt
    92581 ctgatacata aaatagccgt tttggaaaaa gaaaaaagac cagaaaacac aggcctcgta
    92641 gagagatttt tataattctc tctactgtgc ctgcattttt ctgatcggaa tcgtctacat
    92701 aaattctttt attctccggg ggacaaaagc cttgtcatgc ccctttttcc tctctaatgc
    92761 tcaggtcaaa gcgctgaagt catgacgtct tgataaacgg tgttcaagta gctgaccctc
    92821 ggcattagtt ctgaaaaatg caaaatatgg aaagctattt cccatttttc ctctctaatg
    92881 ctcaggtcaa agcgctactt tcacgacctc tatattatca tggtttattg actaccggta
    92941 tccagatttc tcccatatat ttcccgttgg taactcccat ttcgactaca gcatttggac
    93001 ccccaacata ggcgtaatct tctacttctc ttaaaacatg cccaaaggcc gtattcgtca
    93061 aatcatttct taattcttca ggcgattctg ctaaagcgat tacaacaaga tacgttcctt
    93121 ttgggaatgg gatgattcgg gtagtgtttg gaacatcctg actcgtttga acaccgacat
    93181 agtacatcat tttcccgtta tagggttcgt tgactgtaaa gaaataatga ttttcagcag
    93241 cttgtttcaa tgcatctatt gttccattac cgataacttt ttgctcaaat gcttgtttct
    93301 ctgcagccaa accgacaaaa tccgtattgc tactcttcaa ttccacacca atacccgtca
    93361 ccgtaaaatc tggtttttct tcgatcctat actttgccat ttctcccacc ctttctatta
    93421 tattaagttc atcttacata aaattaaagg gaaatgacac gattacgctc ttttttctag
    93481 ggatattttt attttttaac tatttttttg ctttcactgc aatccaaatc tcactgtaaa
    93541 cattactgaa atcctctccc cattttgtaa aagagatctc gggagcttcg actaactcat
    93601 aatctgaaga aggaagccat tctgcataga ttttccccca agtatcttgt aaagtttggg
    93661 gaaatggccc tttattagga aaaatggccc aagtgtgttc ttctatagca agcatttcta
    93721 aatcagcgta cggattttct tttgtcgtag caaagccaat catgtgcatc aaactgccct
    93781 tttcttccaa gcgggctcca tcaaatccat aagaaacgtt gattacttga tttggatata
    93841 aatctcctaa cttatgcatc tcttcccttt gagtctccgt gatcgtctgc gctaactttt
    93901 gtatttcttg attgactcct tcaaatttga caggaacttt tttcgccaca cctgccacat
    93961 aaaactgttc tttcttttcg atacgaaatt ccatcgattt tcctcctctg acatcaataa
    94021 aaaatgtcaa gcgtggaaaa gatttttgta tgccgtatct gctgatttct gaaggcagat
    94081 atcctgacca atcacgaaaa gctcttgaaa aaccttcgac tgtttcatat ccatatctaa
    94141 acgccgtttc tgtcactctt gatccatcta ggagatcgcg attagccaaa gccaatctac
    94201 ggtttttgat atagtccatt agcgacatcc ctgcaataaa cgtaaagatg cgttttaatt
    94261 gatattcaga gattcctgta ttttcggcta ttattttata ggaaagtcct tctgtcaaat
    94321 gttcttcgat gtaatcgatc aattggttca gatctttaag catatttatc ttcctccttg
    94381 cttgcctttt tatcatatta tcaaagaaag tcaattactt gatgaatcag gaaccaattt
    94441 agtcagatgt agaaaatgtt gtatggatct aaagaaaatt ctcaagcagc gtttcgtaac
    94501 ggataattgg tattatctgc ctatctatgt tttaccttta gaaaaataaa ttttggggaa
    94561 gacacattct aagtaaacaa agcggtaaaa atatctttta ttcccttagt taatccgctt
    94621 actacctact gtacaaagca aattgttgtt caaactgctg atcagaacgc tgcttggatt
    94681 tttctttgcg atacatcata cctcttttat caattggaac aattatttat ttctaacaaa
    94741 atcacttcat ttttgtcaga taaataaaaa acaaaaaaag ttccatcttt aaaacacgct
    94801 attcttttac tttttctcac attctctaag aaaagaaaag gagaatgaat ttttgacaat
    94861 tcgagcaaaa gtgattatca aatatgtaaa atcagctact tttttcttaa acgtttcttt
    94921 atactaaata taaataagtg tttcatgaaa ggagaactag atgaataatt ggcttgagta
    94981 ttttcctgaa aacgttttgg aacgcggtta cagctatcat ctgcacggtt ttgtccgtca
    95041 tttgaactat acaagcaagt acttgtccgc aacagtttct ggcacggaag attataaggt
    95101 agtgatcact tgggatgaaa agaccaacat gacttgtgat tgtctatatg ccatagaagg
    95161 aaaaaaatgc aaacacatgg ctgctgtctt attcgcttac gaagaacgtc caataaaaaa
    95221 atccaactac tcactttccg aactctcgtc ccttgtttcc tccgctagtt cctctcttgt
    95281 acgggagctt ttaacagaga ttcttataga acatccgcaa tttatcgaac gcttcaaagt
    95341 taagatgcca tttcatgcaa taaattattc agataaatta acaactatca tccataaata
    95401 cgatcatatt atcaagaaaa acaaaaacag gaaaacagcg aagttcatca tggagatgcg
    95461 aaagttcatc caagaagcag ttgaatcgct cattcagcaa aatgcctatc ttcccgcatt
    95521 cgaattgatc aatgaagtga ttgctactct cgaaacattc tattgggagc ctgaggatga
    95581 acgaaccctt cttctgatag aggactgtta ttatttatgg aaagaattat tagcagaagc
    95641 acctcatgca gaaaaaaggc aaatgttctc ttggttcgtc tgccaagtcg atcatactga
    95701 cgcctcttat tcaaaacgct actccataaa aatcctgaaa gaagactttc gggaaaaaga
    95761 attttctaac caaaagaaaa aaatagataa aaaaactaaa gaaacggtaa agaaagacga
    95821 tttcaatgaa aaatagcaag taaacgataa caaccatcct aaatccacaa gaaatacagc
    95881 agaccttgct ttaaaaacac gaatcatgca aaggatgaag taaagaagac ttaacgcgta
    95941 cccaatatta gtcatttgac tattaggtac gcgttttgtt ttataagtca tgacaaattt
    96001 ccttcgttgc tgggtagatt ttccggcatt gttgatagat tttatgatac ttttctacat
    96061 tttgtaagag aggttccact gcatctgtat attggataaa attctgacaa caactttcag
    96121 gtgtgtcgaa ccactctaat ctttaaagat aaatattaaa ataacgatta ataatattaa
    96181 cagtctttat ttttcaccac caaaaaccta tctttgcata tactaaatag acgtatatac
    96241 acagataggt ttgtcttgtg aaaaataatg attatcctta ccaaaaaatg tttgtttttc
    96301 tacatgttcg tacttatcaa aaaatatgat ccttattgaa attactggct atttatattc
    96361 caacgacttc ttgtgttaat ttttgttatc tcatagtaaa ttatgtttca ttttcactta
    96421 atttagttgt cacgtgttcg tcaattcgta aaaacggtaa atatataaac acacttgcgg
    96481 ctataattaa tatttgtaaa acagctgctc gccagtctcc ggctgttgct aaaaatcccg
    96541 atataactgg tggcgtagtc caaggaattt gcactactac atgattaatt aatcccacag
    96601 cagttgcaaa atatgctact gtcaaagaaa aaatcggtgc aagcacaaag ggaataatca
    96661 gactgatatt aaatacaata ggcaatccaa aaataatagg ttcgcttata ttgaatatag
    96721 cgggagttac cgataattta gcaaagtcct tataatcttt tctacgactg aagataaata
    96781 ttgcaatcaa taaagcaatc gtatttcccg atccacccat taccgcaaag gtatctttaa
    96841 aggccatatt gataatatgt ggaatttgct ctttgtttgc ataagctgcc atattttctt
    96901 gcatattctg aatcaaaaac ggatctaaca atgaacctga tattactgct tgatggatac
    96961 caaatccaaa aaatagatta gcaatagatg taattaacaa aaatcctggt aaaccagttg
    97021 taattttact taatggctct gtaactatcg tggtaattag cttatttata tccatattaa
    97081 acaattgaat gattataaat gacaataaag caaacgaggt aatcgtaata atgattggga
    97141 ttaatacatt aaaagacttt aaaacagcgg gaggaatatt tccggatagc tgaatctgta
    97201 gtttcttatt attagaaagt ttaataaata attctgtagc cgctaatcca acaaatatac
    97261 ctacaaacat tcctgaagct cctgtatagg atataggtat cacacccgtc acttcaacag
    97321 ctttatccgc attttcagga gtaaacatca tctgcatagg tgttaataca acaaatgtcg
    97381 aaatagcaac taataccgct gcaatatgat ttgtataatt tctgcttgca cacatatgat
    97441 aagatactgc tgctacaact aataatgtag ttatgcttaa tgtaccattg gcaattgaag
    97501 taccaatttg ttgtaacgtg gtcaatgtac tagtatcgac aatttccccc atgaatcctg
    97561 ttggttctaa gatcactgaa ttaataagtg tcacaaatcc tgctaacatc ataaatggca
    97621 taaatgtagc aaacgcatct cgcaaagttc ttaaatggat ctgattcccc aacttagtcg
    97681 caactatacc aaatttttca aatacaatgt ccttcctgct acttttgccc atattttttc
    97741 tcctttatgc ttattgtaat cgattacttt ttccacccaa ataatacatc acttatcaaa
    97801 aaaagtaaat acttttaatt aaatatatat atctttttta gtataaaaaa ataagctctg
    97861 aaaaaataat tttcccgagc ttatttttca acaaaaacag cttcaaaaac aaagtcttga
    97921 tataaatgtc tcgataccga atactcgaaa ggtttaccag acgatagagc aacaactttg
    97981 tctatctcaa tcataaattc acctggatct atttttaata tttttgcgtc aaattcattc
    98041 gcagtatctc ctttgatacg tatgtgcgaa gtctttattt ccagacccag ttcatttgtg
    98101 atataagcat atacagattt ctttaaatgt tttggttcca agcctggtat gactgctaat
    98161 ggcatgaatg tttgctcaat cgagtatggt tgacaatcaa taaaacggct tcgtacaata
    98221 ttatatacat agtcttttac actgatactt aatttatcag ctactttttt cgatggaagt
    98281 tcaattgaga aagtatggat ttctgaatct acgtgttctt caccaaccac gctaaacaaa
    98341 ccttcgtttg gaccaagaac tcgtgagtta tcaattggtg ttctgacgac ttcagtccca
    98401 tacccacttc tacttcgcaa aactccttcg gaaacaagta agtctacgcc tttctttact
    98461 gttaacttgc ttgtatgata aataactgcc aattcatctc ctgtaggaag tttctcacca
    98521 attttatact ctccatttac aatttttttc tttatatcta agtaaatttc catatacttc
    98581 gcaatttttt tcaatggtga ccctccaatc aaaaacatat cttcatctat actttaacat
    98641 aaataaaccg ataaaatcca catcaaaatt atacacacaa taaaaaagat atatatattt
    98701 aaacaaaact atttacttta agttgtaagc ggtgttatca ttaagtggaa acaggaggta
    98761 aaaaaattat gacaactatg aaaaagctaa cttttccaga tgatttttgg tggggttccg
    98821 cttggtcagc tgagcaagca gaaggaaaag gagaaacagg aaaagcagag actatctggg
    98881 atcgctggtt taaagaacaa ccttaccggt tttatcaacg aatcgattcc tctattacaa
    98941 ccgatcacat ccatcaatat aaagaagata tagaactaat gaaaaaaact gggcataact
    99001 cctttcgcgt ttctatttct tgggcacgaa tgtttccaaa tggcggtacc ggaaaagtaa
    99061 atcccaaagc catttctttc tatcgaaaat tattttccga aatgaataat aacggaatca
    99121 aagtatttgc caacttatat cattttgaca tgcctgctac tcttcaagat aaaggaggat
    99181 gggaatcacg tgaagtagtt gatgcttatg ttcattacgc tgaaacttgt tttaaagaat
    99241 ttggtgactt agtttgtcat tggtttacct tcaatgaacc acttgggcct attttaggta
    99301 cttatcttga agattttcat tatccaaacc tcattgactt taaacgcgga gcgcaagcag
    99361 cattcttcac tatacttgca cacgcaaaag caatacaagt atttaaagaa ctagctcttc
    99421 ctagtaaaat aggcgttatt ctaaatttga gtcctacttt tcctcgtagt caaaatcctg
    99481 ctgatgtgaa agcagcagaa atcgctgatt tattttatac gcggagcttt ttagatccta
    99541 tggttaaagg gaatttttct aaaaagctta tcctgttatt acaagaatat aatcagcttc
    99601 ctgaagatta tacgaaagaa gatcttgtat gtatctacga aaataccgct caaattcttg
    99661 gactaaacta ttacgagcca cgtcgcgtca aatctcgttc ttctatggtg gatacatcta
    99721 gtccattttt accagagtgg tttttcgaac cacatatcat gcctggacga cgaatgaacg
    99781 aataccgggg atgggaaatt tacgaaaaag gaatttatga tttgtgcatg gatatcaaga
    99841 accattatgg aaacatcgaa gcatttatct cggagaacgg aatgggcgtt gcggatgaag
    99901 aacgtttcat ggatgataca gggcaaataa ttgatgatta tcggattgag tatatcaaag
    99961 atcatcttgc ttacttatgg aaggcaataa atgaaggatg taacattaag gggtatcatc
   100021 tttggacatt tattgattgc tggtcatgga tcaacgccta taaaaaccga tatgggctgg
   100081 tttcactcga ccttactact caaaaaagaa caattaaaaa aagtggcgaa ttttacaagc
   100141 aattaagtga tacaaatgga tttagatacg atgtagactt gttagttgaa taatattcta
   100201 aaattccact tgaagtgaac acattagaaa acaagaataa tgagaaatac caataacaaa
   100261 tactttttct tcatacttca tttatacttg tcagtataag agactgtgac aaatgtagtg
   100321 atcctcagaa gttaggtctg gaaatctaac ttgagaagat ttttttaaac tacgtccagt
   100381 cttttttatt tgtttaaaat tgaagttgac aagtcttcat taaaaattta gaatattcac
   100441 aagtttgacg acaattatga aaatttatgt cgtgctaaag gagttttgtt attggatgaa
   100501 aagttagata taaaaactgc gatcaaagac acgttaccta ccgtttttgg ttatatcggt
   100561 attggacttg catttggtat cgttgggaaa gctgccgggt ttcatccgct ggtcgtcacg
   100621 ttgatgtccc tgctgatcta tgctggttct gcccaattta tcacggtcag catgcttgct
   100681 agccatagtc cactgctctc catcgttctc tcgacctttc tagtcaattc ccgaatgatt
   100741 ctgatgagta tgacgattgc tccttatttc aagaaaaatc ggctgcttca aaatctgctg
   100801 attggcacat tgctgacaga tgaaagtttc gcactgggaa tgaataaatt gaactatact
   100861 ggacaaaagt taaactttcg ttggatgaat acagctaatt ggatttctta tttgacgtgg
   100921 gtgggttctt ctcttgttgg cgcactttta gggaatttta ttactgatcc gaaaaagttt
   100981 ggtttggatt tcgccatcgt cgctatgttt atcgggttac tttatcttca agtcatttct
   101041 gatagaaaca cctctaaacg attacagttg atcctgattg gtctcacttt gattctggta
   101101 tatgtcggac tgatttttat cccaagtaac ttagtgattt tagttgtaac actgattggg
   101161 tgcggattgg gggtgtggat caaacatgcc ttcttttgag tttacattgc tgactatttt
   101221 aggttgtact ttagcaactt ggctttctag gatcctacca tttgtcttac tgaaaaaatt
   101281 cgatttgccg caaccgttgc ttgagtattt aagttttgtc ccgatcgtca ttatgtctgc
   101341 tttatggttc agcagtctat ttacccaaaa tatcggacat ctgccgcaga tcaatctcga
   101401 aaatgctttg gcttcagttc ctacactttt agctgctatt ctttcaaaaa gcttattggt
   101461 gatcgtcttg gtaggaattc tttccctttc gttgattcgc ttattataaa taaaaaaaca
   101521 agagcttatg gcaaattact gtcatgcgct cttgttttta tcaaagtcaa ataagaaaaa
   101581 aatcggcgta ttcttgctta tccgttgaac ggaccactaa caacgacttt tcctaatata
   101641 tgtcctgttt ctacgtcttt ggttgcttgt ttcaagttct tcgcattcat cccatctgaa
   101701 tagaccttgc tcaatgtact gcggataatc ccttcatttg ctaaagcagc aatgtgcgct
   101761 aaagcttctc cttgcgtttc gatttcatag ttatagtctg ttttagcgaa catatactcc
   101821 cagtcgaagc tgatagattg gtttttccaa acacctatat ctaacggctc tttgatccct
   101881 acgatcgttc ccacatgtcc aaatggtcgg acaaggtgtt tgatttgatc aaagtagcgg
   101941 gtaatatcga ataatacagc gacatactct acttgatcga ttcctaattc acgaaaactt
   102001 ttacttaagt cgtgatgata atcgattgga tagtctacac ctgttttttt cagccattca
   102061 aaattcttcg gacttgcagt cgcgtagact tctaggccag cccaatgcgc tagttgattc
   102121 aaaatcgaac cgacgccccc agctccgttg atcactaaga tttttttccc gcggttggca
   102181 ttttcttctg gagtcagacc aaatttttca aataacaatt cataagcggt caatgaggtc
   102241 aacggcaagg ctgcggcttc ttcatctgaa agattttttg gtgcaagagc gacaatacgt
   102301 tcgtcaacca gttggtattc ttgattgctt cctgctcttg tcgttgtacc tgcgtaaaaa
   102361 acgcgatcgc cgacagaaaa tttttgcact tcatcaccta cagcaacaac tttcccgact
   102421 ccatcaaacc ctaagatacg taaagcattt cttatcccgt tatcttggcg aagtttcgta
   102481 tcgacaggat taacagatac tgcgttgact tttaccagaa gatcccgtga actgggtaca
   102541 ggtatctgtt ctttttcatc aataaagctt tttggatcat cgatcgacaa cccttcataa
   102601 aaaccgacta ccttcattaa ttccttttct gacatacgaa ttcctcctta gcttcatcaa
   102661 gttggagcat ccatacagtt ttcatttcaa tatatatagt atgctatttg ttccactttt
   102721 attcatcata attattctct tacttaaagt aaactatttg cacttttttg gttaaaaaag
   102781 aggttgcgac aagacttttg tcacaacctc ttttaaacgg tgttcaatca actgaccctc
   102841 ggtattcgct caaaaaacga caaaatatga ggagctattt ttgtttggct gttcttatta
   102901 cttgatgcag gacagctttt tcacgacctc taattcacgg tgttcaagca agaaatcatt
   102961 gttcactgaa aagcgttgga tgttcttttt caaaggtgtc taagatctct cgtacttcat
   103021 cagtagattt cgtattcatc aactgaactc gcaagtcatt tgctcctgga aatcctttga
   103081 tatagatttt aaagaaacga tgtagtcctg tgatggaacg cgggatgatt tctgaataat
   103141 gatcttgcag atctagttgc agacgaagta gtccgatcag ttctttttct gtatgttccc
   103201 tcggttcttt ttcaaatgca taaggattct tgaaaatccc ccggccaatc atgatgccat
   103261 ctacgccata tttttcggcc aattcttctc ctgtctggcg atctgggata tctccgttga
   103321 tcgtgatcag tgtttgcgga gcgatttggt cacgtaaagc aatgatttta gggatgactt
   103381 cccaatgtgc atctacttta ctcatctctt tacgcgtacg caaatggaca gaaagattgg
   103441 ctatatcttg atgaagtagg tgactgatcc attcttccat ctcagacatt tccgtatagc
   103501 cgatacgcgt cttgacgctg acaggcaaac cgccagcttt agccgcttca atcaattgtg
   103561 ccgctacttc tgggcgaagg atcaagccac tgccttttcc acgttctgct acattaggga
   103621 ctgggcagcc catgttgata tcgattcctt ggaagcccat ttctgccata gcaatgctca
   103681 tttctctaaa aaattctggc ttgtctcccc aaatatgggc aaccatcggc tgttcatctt
   103741 ctgtaaaggt caatcttcct cgtacactgt cttttccatc tggatgacag aaactgtctg
   103801 agtttgtaaa ctcagtaaag aagacatccg gtgctgctgc atgctttacg acatggcgaa
   103861 atacaacatc tgttacatct tccattggtg ctaaaacaaa aaaaggcttt ggcagctctt
   103921 tccaaaaatt agtagtcatt tatttgttac tctccattct atcaagcagt gaagtcgcaa
   103981 tctttctcaa aaacattgtc attatactag gaaacaaaaa aagaagcaaa gtgaacagct
   104041 taaaagatgt ttctgattga gcaaaaaaag actgtgacaa aaatcttatc acaattcctt
   104101 ttccggaata aatggtgttc aaaagcttgc atctgcggta ataagtccaa ccaaacgaaa
   104161 aataggagga gctatttttg tttggctgtt cttattactt gatgcagaac agctttttca
   104221 caacctctcc actaaacggt gttcaatcag ctgaccctcg gtattagctc aacaaacgac
   104281 aaaatatgag gaactatttt cccgtttgtt tctctaatac tcaggtcaaa acgctgattt
   104341 cacaacctct tttctaactt ctcaatcctc ttcctttatt gatcaaatac caagtaacgg
   104401 cgtacaaaac aacgatgaat agcacaagta cgatcatcga tgttgctact ggcacatcga
   104461 ttgttccaag gaatccgtaa cggaaaccga agatcatata aacgatcgga ttgactttcg
   104521 aaacagcttg ccaaaatggc ggcaacatag agatggcata gaaaacgcca cctagataag
   104581 ttaacggctg caagacaaat gtaggcacga tcgatacatc gtcataagac tgagcaaaaa
   104641 tcccgttgag cagtcctgct aacgaaaaca agattgccgt catcaataat gtaatgatga
   104701 ccatgaacca tgaatacaca tgaagtggta caaagaacaa ggaaatgatc gttacgagag
   104761 agccgacgag aatactgcga cccactccgc caatcacaaa gccccaaatg atcacatgcg
   104821 taggaacagg cgctaccaag atttcttcga tgtttttctg gaatttttga gagaagaagg
   104881 acgaagaaac gttggcatac gaactagtga tagcagacat cataatcaaa ccaggcacga
   104941 tgaattccat atatgaaaaa ccacccatgt caccgatccg accaccgatc atttttccga
   105001 aaataacaaa gtacaaggat gtcgtgatca caggcggaac cagtgtttgg acccagatac
   105061 gcaaatagcg gttcgtttcc ttgatagcta aactttttaa tgcagtaaaa taaagattaa
   105121 acatttttct cctccgtatg attattttct tctgtgattt tcaaaaacag ttcttctaaa
   105181 cgattcgact tattcctcat agaaagaact ttgattcctt gtcttgtcag ctgatcgaag
   105241 attccgttca ccccttgatt tcgttcaact tcgacagcga ttgtctgttc atcttcaaat
   105301 gtacaagcgt atccttcaat cacaggtttg gtctcatatg gcgctaaatc aaagataaat
   105361 gtttcaaatt gcagtttgga tagaagctct ttcatactag tattctcgat cagttcacct
   105421 gattggatga tcccgatgtt gcgacaaagc atttcagctt cttctaaata atgcgtcgtc
   105481 aaaatgatcg ttgtaccatt ttcgttcaat tctcggagaa actcccacat ctcgcgtctc
   105541 aattcaatat cgactcctgc tgttggttca tccaagatca gcaaacgtgg ttcatgcatc
   105601 aatgccctag caatcatcag tcttcgcttc attcccccgg aaagcatacg tgcacggaca
   105661 tttctctttt cccaaagatt ggactgcttc aaatattttt cgctgcgttt catcgcttct
   105721 ttgcgagaga caccgtagta gcctgcttga ttcacgacga tttgctggac cgtttcaaag
   105781 ggattgaaat tgaactcttg cgggactaat ccaatctgtt gctttgctcg gactagatcc
   105841 gtatccagat cataaccgaa gacattcact tttccagatg ttttattgac taaagaagta
   105901 atgattccga tcgttgtaga cttcccagct ccatttggtc ctaatagcgc atagaaatct
   105961 ccttctttca cggaaagatc gattcctcgc aatgcttcga ccccacttcc ataaaccttt
   106021 ttcaaattat ttatttcaag cgcatttgcc atttatttcc tatctcctta tagacatgat
   106081 tctttattgt atcatggaat acagcagatg aaaaaacaac ttggttccag cgaaaaatca
   106141 ggttgctggg ctcaggaaaa tctcctaatg aaagacatca atcggacgaa gtcagacaac
   106201 cttttcagaa aaaacaaatc gaagataaag gattactatt catatgtgca acaaaaggag
   106261 cgtgagacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcggaa
   106321 gcaaaagcca agatttttga tccaataaat actttcgatc acttcgccta tcccaataca
   106381 tgccactgcc gcttttcatc aaataacgcg gcttccgttt ttgcggtttc tactaaagtc
   106441 tctgggtaat ccaaaacttt cagcaaggca atcgcatttc gggtccttga aggtccttct
   106501 tttaatttga aatcaaaact gattcctttt ccttctgtta cttgttcttc aaagtggaca
   106561 ttctcacaat aattctttaa aatctctgtc aattcgatat catgtgtggc gacaaatgct
   106621 aaagatggat actccgcaag ccaccgaacg actgaagcgg aagaagcaat ccgttcgatc
   106681 gtatttgtcc cttttaaaat ctcatctacg aagcagtagc agcgttcttt ggaagccact
   106741 tggtccaaca aacgtttgat cgatttgatt tctgaaacaa aataactgtc gccttcaaat
   106801 aaatcatctt cgattgccat ggaagtcaac acatgtccag gttgcagggt aaactgttct
   106861 gcaatcgctg tttggatcgt ctgtgctaga atacagctga tggctatact tttgacatac
   106921 gtagattttc ctgatgcatt ggaacccgtg actaatgtat tcttctgcca gttgaccgga
   106981 ttcactaccg cttcttttaa caatggatga tagatatctt tcgctgtcac accgccctca
   107041 gtaaactctg gtcggcaagt gatgggcata taagtacggt aattcaatat tgcagcggct
   107101 acttctaatt ctcccagcaa ttcccacagc ttgatggctt cagttgaatg cttttctaat
   107161 ttagtgagaa cgaaatgata ggagataaat ggcagcatga acatgatgtt gacatattca
   107221 aaaatcaact ctgcttcact cccactcttc atacgaaatg aaaaacctaa tttagggatg
   107281 tctcttaatg gtttagtttg ctgtttcagc tcttcttgaa gtggtgtcgg cagttttgct
   107341 agctgattgg cggctgaaat cgttgaaacc aaataactca tgctattcag ctctgtttct
   107401 agtgtttgtt tcttcactag ataatagacc gtattgaata ctaacccacc gattgccaaa
   107461 tagattccta gtacttgtcc taaaagaagc aaacccaaac ccaccagcgg aagcaagcca
   107521 agaaaaataa ataaacctac gcgtccaatc tttttacttt ttccatccgc tagatattgt
   107581 tttgcaaaat tatgatcttt ttttcctaaa cgagcgaatt gatattggat tttttctctc
   107641 agttgaggat tttcctgata aaaagcaatc agtttttcta actgctgatc ttcaccaaaa
   107701 tcaaagctgc gtaaacgttg atacaacgct tctgaaccta cactagaata ggtactgttg
   107761 attccttcga atacttcgaa catatccagg tcataccaag taagatcatc gatttcgcta
   107821 tcccatgaac ggaacttctt ctccgtgagc catgcttcct tcaagctttc ttctttatca
   107881 aatctcggtt gataaggaat tttttcccat ttgctacgaa ctgtttcctt taatttcaaa
   107941 cgtgaaaaaa tgtctaaagc aactaataaa ataacagctg caataataat taaaacgata
   108001 aattctcttt gacccatatc cctctccgtt cctttatttg ttagctttag tatagcactg
   108061 ttgcgctatt tgaaaagagg gtaaaaaaac acctttcaaa ataaaaggtg tttttttctt
   108121 gtatattaca tatttatctc tcatttatca aaattgacaa ataatcatag ggaggaattg
   108181 ttgttaattc ttgtttattc tccagtgcat tgacaactgt cccaagggaa aggatagcct
   108241 caggtactat tttttcttgt tctgttggat tagctaagcg aagaacaaat ccttgttcat
   108301 gaaaataaga aggataaatc gatgatacaa ttaagtcttc aggtaattca atcaatgaaa
   108361 atttacgagg aacatcaagt tcattttgta atggccaaat cttgttatct aacctgtgaa
   108421 taaatacatt cagtttctgc ttttgataag aaatagattg ttctaaccgt ttttctgcct
   108481 gttttgccac tttgaactca ttaaatcttc cttcttctac attaaatcca aaagtgactt
   108541 tatactcacc tatctcttga gctagcggtg tttccatcat gacatgccct tcatttgtcg
   108601 tatctcctga agctcgccca ggtcgccaag caagattagg ttttccaagt tcccctgttg
   108661 ttgaaaataa ggttatgatt aattgatttt ctatacgttc atactctttt aaaccatctg
   108721 cataaaacgt aaaataatga tcattttctg ccacagagac actcttatcg aatatttcta
   108781 aattaacagg tttctctacc atagtttctg accaattcgg aggaatgaca tcaggggtat
   108841 tttcaataaa tccgttttga atttgtgcaa ttgatttttc agatttatct aaaacattaa
   108901 ttgctaagcg catacgatgc gagtaaacag tattatgaat tttgagtgtg ccttcaacga
   108961 tttgactttc tcccagactg aacgatattt cataagatat ttcttccatt tcgggttttt
   109021 cagataaacg atcttttaaa tctttaggaa gttgagcttt tccgtaaaca actaatgttt
   109081 cttgtaaaga atctttatat actttagctg tttctaattt tagagatagt tctgtatctc
   109141 cttctaatgg tgaataatca tacgtatcgc catcatttgc tgaatcgatc aaatgaacga
   109201 aatcaagata ttgtctatct ccaactatca aattcaattg cccatcttta aaagaaagtt
   109261 tatatttatt gttacttatc tcagttttgt ctatctcgat tgctgtttct aatttttcat
   109321 tatttttctc aaattcaaca acagtgtatc ctagtgctgg cacatttaca tttattttta
   109381 tgtcaagttc ataataagct ggttcatcaa aatattcgaa acctgtagca atcatccgat
   109441 aagcattttt ccgttctgga aaataaactt ctttttcaat gatattatag ggactacctt
   109501 tgaagtgtat tttctttgaa tcagctacta catgcacgat tttcgatcca ctataattct
   109561 cagtcgttgt gttgaaaaca aggacttcat tcgattttag ctttaatgca tcagccatcc
   109621 gttttacaat aaggttttcg attccgtcag ctatctcatt agcttctttg attcgatgga
   109681 aaatatcttc cgcaacatta tctgaaacac agccaccaat actatcatga gcctggtttt
   109741 gcaaaatctt tttccataac cgacgaagta ggcctttact gatatggata ccatttcttt
   109801 ctgcaatcag catgagcggc tcaactcgtt ttagaatttt ttgttccaat ttaaaatttt
   109861 ctattttcat ttttgttctt actgagccaa tagaacgatg aacacgagag taaaccggct
   109921 gacgaagttc acctttatat tcaggtaatt cttttttgtt tctgataact tctacataag
   109981 aaggataatc tgaaataata ttgtggaatt tactgtattt attcaacttc tctacgactt
   110041 gatcaaaatt taaaatcatt gacttttgat ctacacccga aggtactaaa atatctttgt
   110101 tttttccttg catatgaagc atttcaactg cttcatccaa cttttctttt gcaaattcag
   110161 gaatatcttt aattgcgtct aaggtcatca ttccagtcat ataaccaaat ggaaaattca
   110221 tggcataaac aaatttatct cccaatcctt tccagataaa ataaggagat ggaaccatcg
   110281 tttcaaagtt taatcctcgc caacacatga aattatcgat ttctacttga tgcaaaagtg
   110341 taggcaaatt cgcattgaac ccaaacgtgt caggcaaata ccctaccatc attggatctc
   110401 catatttaag gatcgtatca ctgattccaa tcattaagtt tcttaaaatt gattcagcat
   110461 ccactaataa ggcatctgtt tgtgcatacc acggtcccac gaatagttgt cctgttttca
   110521 tcagtcgttg gataacctta agcttttgcg gattgatctc caaatactca tcgacgattg
   110581 aagtttgtcc atctaaacaa aagtttactt tagggttcct ttccaattca tctagaactt
   110641 cagtaaagac ctgatcagac aatacgatgg catcttcatt tgtaaaatac cattctctgt
   110701 cccagtgcgt gtgttgaatt atatgtgcat ttaccatatc agattctcct actttccttc
   110761 ttctactgaa tttacttgtt gttctttttt atacttgatg gattttagtg cattgaccat
   110821 taacgctgta accactcccc caataacaat tgatactaaa tataaaggta tattcgtaac
   110881 aaaaggaatt gccataaagg ttgaaagcat tgtttcttga gtaacaccaa aaaatccatt
   110941 tagaccacat gctactgcag tgcccaccac gatgcttggt attactcgta aaggatcttt
   111001 cacggcaaac gggatcgtcc cttcagtaat ccccacaagg cccataatca tagctgtctt
   111061 tgcattatct cgttccgatt catcataaag ttttttgttt aaaattgttg ctaaaaacat
   111121 tccaaatggc ggaatagcaa ttcctaataa catggctgta ctaggtccaa agcttccgct
   111181 tgaaaaagaa gcaaccccaa aagcatatgc gattttattg ataggtcctc ccatatcaaa
   111241 cgccatcatt cctcctaaaa tagccgacat caaagcagca tttgctcctg acatgccttc
   111301 tagccaatta gtcagtcctg ttgtcattgc ttgaataggc gtagctagta cataccataa
   111361 tatgattcca acaactaatg tagtaacaaa aggaatcagc ataattgatt ttagactaat
   111421 aacttgcatc ggtactttta cttttttcaa tgcattagct aaatagccac aagctaatcc
   111481 agcaaccatt cctccaataa atcccatacc aagattttga cacatcatcc cagtgataaa
   111541 agctggtgct agaccgggac ggtcagcaat tgaatatgcg atataggctg aaatcatcgg
   111601 tacgataaac tgtaatcccg tctgaccaat cattcgcagg actccccaga atgtatccgt
   111661 ctggtcccaa acacctgtgc caccaaaaat gactgcaata gaagttagta accctgctgc
   111721 tacgacaagc gggatcatat aggaaacccc actttggaaa tgatttagaa tttctcttcc
   111781 ttgtttcttg aattccatta gtaactcccc cacgatatat tttttatttg ttaattaatg
   111841 caattgcttc atcaatcgtc tcttcaccat cttttactac ctctgaggtc cctactgtta
   111901 aaatcggttt accgtcaaag cgacctcgtt ctgaaacatt tgtatctact gcaaatatga
   111961 caacatctgc ctcggaaaca tccgaaattg aaagtttgtt ttctatcccc atagccccct
   112021 gtgtttctac tttaatatct aaccctttct tcttcgcaaa cttttctaaa ttagcttttg
   112081 ccatataagt atgggcaatc cctgcgatac atgctgttac tgctactatt tttgtcatat
   112141 gaaattcctc cttttaaaat gatagagctt ttaccaattc ttttttattt ctcgaatctt
   112201 ttattctttt aacaaactcg tcatccatca atcttccaga taattctgct aaaatacgta
   112261 aatgattagt acctttatca gtgtctttta ttgctaacaa aaagacgaga tcaactggtt
   112321 gatcatctaa tgcgccccat tcaacagacc gctttaactt ggctacagcc actgttgatt
   112381 caattactgc taggcttttg ccatgaggaa tggcgatatt tttcccaatt cctgtggtca
   112441 tatggttttc tctgtcaaat acgtcttttt gaaattgttt gtggtcagac acaaacccat
   112501 tagtctctaa caatttcgat aatttttcga ctacactttt tttatcagat gcatttaaat
   112561 ctatcactat attatttata ttgatttttt cactgatcat ttataagcct tctttcaata
   112621 tataaactaa tttttcaaac gacgaactcg tttttaaatt tgctaataac tcatgattcg
   112681 aagcgatttc attgaatgtt tcataaattt tattcaattc aggttttact ttttcattaa
   112741 gtgcaaaaaa gaaaacagaa tgaacaagtg tcccatccca atcaattcct tctggattaa
   112801 cgtagacaca gattactggc ttttttataa aatctacttc gatatgcggc atagcaaaat
   112861 cattcatcgc tgttgaagat agtttttctc ttttgattgc tccctctagt atcccttctt
   112921 tcgcgtaatt ttcttttacc aattttttgg taattatatt taaaacgttc acttgattat
   112981 cctttatttg gtgggtaaaa aagcaaaatc gtttatctaa taaatttaga aaagcatctt
   113041 ctgtttgttc atttaactgt agatactgtt ttacttttct gacatctgcc cctaacatca
   113101 aaggactaac aacaataaca ggaaaatttg tattttcaat cggaatcgtg cttataacaa
   113161 gttcatcagt gacttttcta tcttgtagtt cattgatgct tagtacatct tctatctcaa
   113221 ccatatctgc aaaaccgtta tttattcttt gctctaataa ttttgatgtt ccatatccgc
   113281 tactacaaac taatatcact ttcgttttgt caggtttgta acgatccaaa agtgattgaa
   113341 tatggagtgt tacgtaagcg atttcatctt cattaaaatg tatacagaat ctctcttcga
   113401 tttcctctaa taaatctaca cttatcataa atgacctttt aaaagaatat ttgattttgt
   113461 ccgtataagg gttatagata tttactccca atttgagtct tttaactgct gcattgagat
   113521 gtaatactag attattgatc aattcttcat caggataaaa ttcatttaat ttaattctta
   113581 ctaactcttg tagctcaaca cccatatcta aataggaaag cttcgtttga tctaagtcgt
   113641 gattcatagc atttttttca atcgaagtaa tgtgaatgtc aacataagct tgttcatcta
   113701 ttggcacaat aattgaaaat gctttttcaa tcattttgat taaaataagt gtattctttg
   113761 agatttcttc ttcagaatta ttactacgtg ataagaaatt gcttgtttca atcctttcta
   113821 tcgcaatagc aaggtggata gctaaagttt gaaattcata atctgtaaat ttcaattgtg
   113881 tcttattcat gtatcgatta agcaattcgg ctactttttt caatatgtcc ttatttaaga
   113941 aattattcgc ttcaccaatg aaattgatat tcaagtctaa gagatctgtt ttactgttag
   114001 atgctgtaaa gccaccccaa taatagttca caacttctga catcaacctt cttttacttt
   114061 tttcatcagc tttgatgcgc acgccatttc gatctgaaac taaggacatc ccatgcttgt
   114121 ttagtctttt tctaacatct ttcattgtgc tttctaccgt cgacctgctc acgtataatt
   114181 cgtcagcaag attttgaatc tttagagaat cattagtatt caataattta gcaaacacat
   114241 aagttagacg gtcctccgga gagtctgcga tattgatttt atgactggat aataaatttc
   114301 gaagtgtttc tttttttcca ataagcgaaa cgcctttttt aggttgaacc aacatttgta
   114361 catctggcat tttttggatt atttctttca aaattaaaat atctttgcta attgttttcg
   114421 tagatacata taattgttct gataattctt tgtaagttgt gtgctcattt tcaatcaaaa
   114481 agtatagtat tttcatttgc cgttcgctaa attcgatgcc cattatcttc acctcctgaa
   114541 tacagcttaa gtgtacaatt attatctcta ttttcataca gaagaaagtt cttgattaat
   114601 gtagaagttt ctaatattct tgattatttc aaatcaataa aaaagcctgc aatatttata
   114661 tcacaggctt ttttctctat taaatatata taagataata catttttcta ctagttctca
   114721 ctaatcttgt ataattaaac cctccgcaac ttgacggaga tggagaagat gcccccgtct
   114781 aatctagcgg tcatctctcc tcccattcct tccaccaatt tttttgacag gtaaagcccg
   114841 attccgctag attccgtatt tgtgcggctg gtattttcgg tataaaaacg ctggaagact
   114901 ttttcaacag aggtttgcgt tcctggtttg ataggattgg ccactgttaa tcgaatgaat
   114961 ggatcctctt ttgaaaatgt cacctttgct tgtccatctg cataacgcaa taaattctgt
   115021 atgatatttt gcagcactcg cagcaacatg agcggatctg ctaatacagt tgtatttatc
   115081 gagtgttcag cgaacgctac ctcgatattt ttctcagaaa attgttcata aaaagagaaa
   115141 aatacttctt ccacctcttt agaaaaagaa agcgtatgga gatccatttc tttttgcttc
   115201 gtctctattc gagcaagatc ataaaactga tccgtcatac tgagtaatct tgcaacagat
   115261 tgtttgatga tcgttaaata cttctcccgt ttctccgtat cctctacctg ttccagtaat
   115321 tgtacataac cgttaatagc agtcaaagga gttctgagat catgagaaag gccgacgatc
   115381 gatagtctga tgttttcttc catttcttga aatgcttgtc ctttttgttc attttcatcc
   115441 aaccatgtat tcagtgcatc tactaggtcc attagattct tttctcgaaa ttcgactgaa
   115501 agacgaccac catattcttg tcgttcagaa agagtggcga ttttcttagt taatctcttg
   115561 atttcccttt gcaggaagaa aataaaactt cccataaaga taacaacgag aagcaacagc
   115621 catttaatca aatctaaacc ccactcccca caccgtatga atatacacag catgtgcctt
   115681 tgctagcttc cctcgaagat tggaaatatg catattcact gttttctcac tatcaaaata
   115741 tggttcttgc caaactgttt cataaagatt tgctcgcgaa aatacttttt tcggatgttc
   115801 taaaaaaagc ttcagcagat cgaattctct tcctgtcaaa tggacagcca caccattcac
   115861 atttacatcc ctcgactctt tgtccagtaa gatttccttg taatagatgc gttgcgacag
   115921 atcttttact tggacagaag tctgatgacg aagttggatg ccgattcgta acaaaagttc
   115981 ttcgatatca aatggtttcg tcacatagtc atccgctcct gctgccaaca aggaaacttt
   116041 atctctttga tcgctttttg ctgaaagaac gatgatcgga acattcgatg tctgtcggat
   116101 ttctgctaac aatgcttcac ctgaaagccc tggaagcatg agatctagaa ggatcaaatc
   116161 gacaggatat gtgcttaaca ataattttcc ttccgtacct gaataagcat caagaagttt
   116221 gtatctctgt tcaagaacct cctccagtaa ggaatgaaca gcttcatcgt cttcgataat
   116281 caaaatagtt tccagcagga ccacctactt aatgtcagat ttttggaaaa taaacattcc
   116341 tagagctgat gataccacga ttgttactag actgaccaga atcattttcg gtgcttgcga
   116401 ataagttgct tgttgcgcaa agtccgtata catgagccac gtttccgtaa accactccgt
   116461 tagaaattcc aagcctttga tttttgcgaa aacaccggga atgaaggccg ttcccatgat
   116521 ataaagaaaa gaaagaagca aactgacact ggtacttcta gtgatgaatg tcaaagccac
   116581 tggaacagat aatgtcccta atgtcagcag aagcaataca ggaaatactt ttagaacata
   116641 atttccatag tttttgattc cctcaacttc accaaatccg aaagcaagtg tgtaagcaag
   116701 catggctagt cccgtgatca aaaccacgcc aagtgttgtg atcaaaagcg taacgagaag
   116761 tttcgacaca taataagtca ttcgattccg tcctaaagat aacgtattgc gaatcgtacc
   116821 gttttgaaat tcttccccaa tataaaagca cgcaaatgct gcgaaagcca gaagaatcca
   116881 tgcagccatt ttttctacca ttaaaatccc tgttgcaccg ttgatgactg tatccgttgc
   116941 ttggtttaat tcattgccgt attttgtatg catataccat tcgttccaag aataaaaaag
   117001 cggaagtacg accatcagtc ctagtgagac ccacatttta cggctcttcc atacttttat
   117061 tttttcagca gttaatagat taaacatgtg gattgcctcc agttaattgt aagaaataat
   117121 cttccagttt ttgcccaact aggtgaatac catccacagg aacttttgct tctaccaatg
   117181 cttgattgat ggctgctact tggtcaattc cttcaaaaag ctggataaca cggctagatt
   117241 gtacaaaata atccctataa ccaagagagt cgagaaccgt tactgcttgt tccgtcgccg
   117301 aagtgtcaat ttttataaat tgacgagatt cttgtgccaa ttcttctttc gataattctt
   117361 tgatcaagtg tccttcatgc aaaataccat agtgagtggc gatctgtgac aattcatcta
   117421 gcaagtggct agaaagcaag acggtgatgc cccgttcttt taccaaacgt tggatgattt
   117481 ctcgcatttc tgccatccct gctggatcca tcccattcgt cggttcatcc aaaatcaaaa
   117541 attctggatt cgtgatcagt gcatttgcaa tagctaaacg ctggcgcata cctaaagaga
   117601 aattctttgc tttctttttc cctgtatttt ccaatcgcat cattttcagc aggtcttcga
   117661 tttctctatc cgacacaccg ccgttcgctg cttggatacg taggttatct cttgcagtta
   117721 attctggata aagagcaggg gtttcaatcg attgacccat acgtcgtctt gctgcctgca
   117781 aatccgtcgt tccaaataat tcgatcgaac cttcatcaat cgagatcaaa cccataatag
   117841 ttctcataaa ggtagactta cccgctccat tttccccaat caatccatag atcattccac
   117901 gtttgatttc gattgatact ttatctaatg ctttggcagc accgtatttt ttggttatac
   117961 cagttgcttt caagaccgtt tcatttccaa aatccatact tatccttctt tcttattgat
   118021 gagtgaagta tagttgacgg gtataaagaa agcagccaga aatgtataaa gaaagtgtaa
   118081 attttccaat tgaatgtcaa aaaaaacaat cggacaatac gtgtctttcc tattatcagg
   118141 cagtttgtta tacgcttgta tcagtttcct gattctttct tttcgaccaa agtcgtttct
   118201 ctgtattcct cttcactgaa aatttttgct tctttcagat caagcttgag taattttacc
   118261 agaccggtta taaggataac tatagcaaga ctccctccca gaaaaattag actgtctcgc
   118321 agacgtggtt gcgttgtctt ccaatcaaag agcgcaccaa acagtgctaa tccaagtgga
   118381 ctggccacca tggtaatcgt tgttatcgtt gacataagtc gtccttgtat atgcgttgga
   118441 acttctcgct gaagccagac catataaaaa gcaaaagaaa acattaatcc ttaaaaacgg
   118501 acttatgaaa aataatacat gccgtttggg atttacaatt agctaccaaa taagaggtta
   118561 tgacaaaaga cttttcacaa tcccttcttc cgaataaacg gtgttctcct gccaactcct
   118621 cggtcacaag tcacaatatt tatcaaacat gagaagcaat ttttgtaaat tccttcttat
   118681 ttcttgaagc tgaccacttc tgtcacaacc tcagaagcgg ataaataata ttgtttgatg
   118741 atactttatc tttttcccgt ttgtttatag atcgaatgat attatagacc aagaatccta
   118801 cctattaaca tagctaaaaa cacaaaaaag gcactttcca aattgtggaa agtgccagaa
   118861 aagttaggat taaggtaact gcgctcagca ttgcttcgcc cagtacgatt ctcgtaactc
   118921 gtgaactcga acgataatcg caattaacgt tttgagaact gtgaagcttt acgggctttc
   118981 ttaagacctg gttttttctt cgtatcattg aataagtttg aaaaaccttg atttataaag
   119041 gttttcccgt aaatatattt tattatattt gattaaattt gaaatgtttg tgttctaaaa
   119101 tgtgttctaa tttaaaggca gtatatttcg tattttagat taaattttta ggctcattca
   119161 ttctcaaatc cattctattc agtcaataaa aattttaaaa agactttata aacaaagatg
   119221 ttcaagcgag catcttattt ttttgtgctt aatttgaaag gagaacattt catgtataaa
   119281 aaacaaaaaa agaaattatg tgtattaact attttgagtt tggctgttca agcaattgtt
   119341 ggagcaattg ctcctacgat tacttttgct gatgaaatta cccatccaca aacggtaacc
   119401 gtagaactag atttagcaca tcaatatgct gttgaaggaa cttttagtga tggtcgtcca
   119461 atgtcagaag tcactgttcc gcattatgca gtgtacaacg gctttaaaca agatattttc
   119521 tgtattgaac caggagtccc gatttacaat gagttcactc ctggctatga gaaaaacccg
   119581 ttaccagata tgtccgataa agccaaatta gtttccgttt tatggaaaaa agtaggtaca
   119641 gatgcagata ctcatattgt ggcacagaag atgatctggc aagaagttaa tgggtatacc
   119701 cttcactcaa taaaacgatc agatggtagt gccgtaaata tcgcagccat tgaggcaaaa
   119761 ataaatcaag ccattgacga ttatcagaag aaaccaacct tccataatag tacggctaaa
   119821 acagtattag ggcaatcgac tactgtgacg gatacgaata atctgaattt gtcagagttc
   119881 gatgaggttg tggaaaatgc cgcaaacatt gattatcgtg tgaatggtaa tcagttgata
   119941 atcaccccaa atgccaattc aaaagaaagt ggtgtgctga cgcttaagaa atctgctggt
   120001 accggaacac ctgtcgccta taaaaaggct ggccaacaga ctttaatggc cggggcgatt
   120061 gataaaccta atacctacac aatcaaaatt gatgtggaaa cggagggttc tttaaagatc
   120121 aaaaaagtcg ataaagaatc gggtgatgtt gtaccaggaa cggttttcca tttagacttt
   120181 ggaaaaactt tacctgcaaa agacgtgact actgacaaag aaggcattgc tacattggat
   120241 gagattcctc atggtacaaa agtaaccatt accgaaaaat cagtaccggc gccttatacg
   120301 attgatacca cccccatgac taccaccatt aaagcaggcg aaaccattta cgtgacttca
   120361 aaaaacgcac gggaaaaagg gcaaatcatt ctggataaaa gcggagttga aacagggagt
   120421 gatctttgga atgacaatta ttccttagct ggtaatacgt ttgccattcg caaagacagt
   120481 ccaaccggtg aaatcgttca agaaatgacc acggatgaaa acggtcatgc ggaaacacca
   120541 aaagagattg ctaatgcgtt ggaattggga acctattatg tgaccgaaac taaagctagt
   120601 catgggttcg tgaatacgtt caaacctgta aaagtcgaat tgaagtatgc caatcaaacc
   120661 gtagcccctg ttaccagtaa cgtaaaaggg caaaatcaag aagtcactgg cgaaaccact
   120721 ttgacgaaag aagacaaaga tactggggat aaagcacaag gtaaggcagt ctttgagggt
   120781 gctgaataca ccttgtttac tgctaaggat ggaaaagctg ttaaatggag tgaggctttt
   120841 aaaccagagt tagcgaaggg aacgaaaggt tctgatgaaa cggtcacttt gactttagac
   120901 gaaaagaacc aagttgccgt taaacattta gctatcaacg agtattattg ccaagaaaca
   120961 aaagcgcccg aaggatatag ccttgatgaa acaaagtatc ctgtatccat caaaaaggtg
   121021 gatgatagcg aaaaaaatgc cgtgattacc cgaaatgtta cggcaaaaga acaagtgatt
   121081 cgctttggct ttgatttctt taaatttgct ggatcagctg cgggcactac cgaaactggc
   121141 ttcaatgatc tgacctttaa agtgtcgcca ttggaaggga ccaatgaaat cacaggtgcc
   121201 gaagatgaag cgaccacagc ttataacgag caattagggt ttgatggtta tggcaagttt
   121261 gaaaatcttc cttatgggga ttatttactt gaagaagtag aagccccaga aggttttcaa
   121321 aagattacgc cattagaaat ccgttctact tttaaggaaa acaaagaaga ctttgtgaag
   121381 agtgagtatg tctttaccat taccgaacaa gaccaaaaac aaccaattaa aacggtgacc
   121441 gttccttacg agaagctgac gaacaaagca ttttctgtta gtttgaaccg tttaatgctc
   121501 tatgatttgc ctgaggaaga agatagttta acttctcttg cgacttggaa agacggaaac
   121561 aaagaattaa cttctctgga ttctaccgag ctagttgata aattgagtta caatctacat
   121621 gaaatcaaag aagactggta tgtggtagcg caagccattg atgtggatgc gacaaaagct
   121681 gcccaagaaa aagatgaaaa agccaaacca gtggtgattg cagaaacaag cgcaacgttg
   121741 gcgaacaaag agaaaacagg aacttggaaa attcagcata aattaaccgc cgaacaagtt
   121801 ttaaataaaa ctattgtctt attcaactat gtgtatgaaa ataaggaagc ttttgaagca
   121861 ggcgataagc cagtagcgaa ggatgttagc ttgaataacc aagcccaaac tgtcagttgt
   121921 acagtggaac accatgtttc tatccaaaca aaggcccacc tagaaaacgg ttctcagacc
   121981 tttactcatg gtgatgtggt ggatatgttt gatgatgtgt cgattactca tgatgtactg
   122041 gatggctcaa aagaagcttt cgaaacaatt ctgtatgctt tattaccgga tggtacaaac
   122101 aaagaaattt ggaaatctgg caagattgat tatgaagtaa atgataaaga attcaccaaa
   122161 actgtgcttg cgaaaaaagt agataccgga aaatatccag aaggaaccaa gtttactttt
   122221 gcggaaatca attacgataa agatgggaat atcaatggaa aacacaatga agatttgaaa
   122281 gaaaaatctc aaaccttaac accaaaagaa gttccaacca tactaagtac gccgaaacaa
   122341 ccggaaacac caactgttcc aagtggctct caagaatcta gtcccacagt gaagaccttc
   122401 cctcaaaccg gggagaaaaa ttccaatgtt ttactgttca ttggttttac tttgattttt
   122461 gcgacggcgg gctattattt ctggaatcgc cggaactaag gtgatgagat gatacaagta
   122521 aatcctaaga accaacgtgc gcgaccgcct cctaaaaaag tagtcgcgct atttttgtat
   122581 ccaaaactaa caatgaaaag aggaaaagaa gatggaattg aaatttgtcg tgccagatat
   122641 ggctgaaacc tttggaaagt taagttatgc cggtgaagga gaaattataa cagaaggata
   122701 tggacggaat actacggtga ttggtcgcag ttatcatttg tattccagta agcaacgggc
   122761 cgatgatatt gaggtggtag tagctgcgga agccggtgaa aaggattttg atcaagacca
   122821 accgctaaaa gccgtgaatc cccatttggt tgccaaaggc tatgagattg agaatcgtgg
   122881 gtttactgat tacgtgttgt atgttgatga tttagtgaaa gcataggagg aaaagaagat
   122941 gagattaaca gaaggtattg tcgtagattc aggtttaaca tttgggaagt tgcgtttttc
   123001 cgcattacgc cgagaagtac ggaagcaaaa tgaggatgga acaattggta atgaggtaaa
   123061 agaacgaacc tataatttaa aatcctctgc acaagggcga atgattcaag ttagtatccc
   123121 agctaatgta cccttacgcg agtttgctta tgatgcagag gtagagttgg tcaatccaat
   123181 cgtggatacc gttgccaatt atgtttttcg agaaggaact accgttaatt ggttcattaa
   123241 ggcggatgat ttagtcttga agcggcagcc gaatcaagga aatcctacga accaaaatga
   123301 aagaaagaaa taggtgaaga ttatggaaat taatgttgaa catattttag attgtctcga
   123361 tcaatatgga aaaggcgagc tgactgagga acaactcgtt aaagcattaa cctctgatga
   123421 aaaaatgttt ctgattatac atcaaggttt acttggagaa aatagcgaca gtgaagaaga
   123481 ctctgatgta ctagactggt taggagaaga agagtctttc tttatagttg tcgaagtaaa
   123541 tgaaaactta tgtcggcagg cagaatccat tttggaagaa attggtgtgg agatgccgga
   123601 tgctattgaa ggctttttaa atcaattggt tgaaacgaaa caactcccct cctcgtagca
   123661 gtaaatgact agcataactt tttgaaattg cctaatgaaa tcctattggg ctttttcgat
   123721 tggaggtgga aaccatcaaa atgtacaaag gacatcgcat acgcgcagga gatcagcact
   123781 tggtttatca ctttgttctt ggctggctac tcgctctgtt catcggttgg atgagcgtct
   123841 tttattttca agagtttaga caatttgata tttctaagct atcactttct actattgaaa
   123901 tcgtttggtc tataaaagat ttagtatgtc tgcttggaag tctcgctttt tcaggagcta
   123961 tgatattgct ttatattcac ttttttcttg atcattggcg aagcttgtgg catcgacaaa
   124021 agctagctcg gatgattcta gagaaccatt ggtatgaagt gaaacaaact caaagtgaag
   124081 gctttttcaa agatttgaat agtagccgaa ccagagagac tatcagttac ttccccaaaa
   124141 tctgttatcg aatgaaagat ggattactgt ctattcgcgt tcaaatttca cttgggaaat
   124201 accaagatca gcttttaaaa ttggaaaaga agttagaaag cggactgtat tgtgagttag
   124261 tagaaaagga actcaaagac tcctatgtgg agtatacttt actgtatgat atgatcgcca
   124321 atcgaattgg gatagacgaa gtagtggcag aaaatgggac tctgcgattg atgaaaaatc
   124381 aagtatgggc ttatgattct ttaccccata tgttaatcgc tggtggcacg ggtggaggga
   124441 agacctattt cctcctcacc attatcgaag cactattgaa gtcagatgca gaattgttta
   124501 tcctcgatcc caaaaatgca gatttagctg atttaggtac ggtgatgcct catgtttatt
   124561 cacaaaagga agaaatttct gcttgtgtgg aagatttcta tgaacgtatg atggctcgta
   124621 gcaaggcaat gaaagaaatg tctaactaca aaacaggaga gaattatgcc tatcttggac
   124681 ttccacccaa ctttttaatc tttgatgaat acgtggctta tatggagatg ttaacgacga
   124741 aagaaagtgc ggtgattttg aataagctca aacaaatcgt gatgttgggt cgtcaatctg
   124801 gtttctttct gattttggct tgccaaaggc cggatgcgaa atatttagga gacggaatcc
   124861 gcgatcaatt caactttcgc gtggctttgg gtcgtatgag tgaactcgga tattccatga
   124921 tgtttgggga ggtcgaaaaa aacttcttta tgaagcacat caaaggtcga ggttatgtgg
   124981 atacaggtgg cagtgtgatt agtgagtttt atacgccact tgtaccaaaa gggtatgatt
   125041 tcttagattc aattagtaaa ttagaaaaga tgaatgattg agtgatcttc aatactgact
   125101 ttatacttca agtaacgtat aatactttta tatagtagga agaaagggga taattaatat
   125161 ggaaagtaat gattcttatt tagagtatgc aaaagcaaat aaggataagt ttatttctta
   125221 tattatcaaa gggaaatccc ccgaagttgg acgagacgca gtttttatgg cagggagtcc
   125281 tggggctgga aaatcagagg ttgccattgg attagctgag aattatgata accatgtgat
   125341 tattgatgcg gattactttc gcacccagtt tcctgattat aatggaaaaa actctagtct
   125401 ctttcaaaaa gcatcttctt ggttggtaga gcaggcattt agatatgtct tagatcatgg
   125461 ctattctttt attctggatg caacttttgc aatattaagt gctgaaaaaa atatctcgcg
   125521 ggcgttgaaa aaacattttc gagtgacgat tttctatgtt tatcaagacc ctaaaatcgc
   125581 ttggaaattt acacaagaac gtgaaattgc agagggacgt catgtgccga aaaaggcatt
   125641 tattaacgct tttttcaaat caagagagaa cattgcaaaa gtaaagagta aacatccaga
   125701 tgtattgctt catatcataa taaaagatta tacgaataat atttccgaag ttcattatgc
   125761 tacggataat ctagaattat ttttaccact agggtatagt aggaaagatt tggaggttca
   125821 attacatgac tgagaaagaa caagtaacga aaattgtaaa gaaatacaat aagagcattg
   125881 cggatttatc ggaaaatgct actgcaaaag agttcaaaac ggtgattaaa tatgtagccg
   125941 atcaggccaa tgaaaaacaa cggaaattag ttggattaaa taaaaaatag taggacaaat
   126001 taataatgta tgagccaaga gcaaaatgtt cttggctttt ttctttgcaa tgaatgaggt
   126061 aatgtatgag atttttagat ttattcgccg gtattggtgg ctttcgttta ggtatggaac
   126121 aggcgagcca tcattgtatc ggtttttgtg aaattgataa atttgctaga cgtagttata
   126181 aagcaattca tgatacaagt aaggaggtgg aaatgcatga catcacaagt gtatcagatg
   126241 agtttattca atccctcgga ccagtggaca tcctttgcgg cggatttccg tgccaagctt
   126301 tttcaattgc gggaaagcgg caaagatttt ccgatactcg aggtacttta ttctttgaaa
   126361 tcgctcggtt caccactctt ctccgaccta agcttttatt ccttgagaac gtccgaggat
   126421 tgctcaatca cgaaggaggg gctacgttcg agacgatcct ccgaacgctg gatggattgg
   126481 ggtatgacgt ggagtggtag gtgcttaact caaaggccta cattccccaa agccgggagc
   126541 ggatattcct tatcggacat tctcgagacg catgtaccga acaagtattt cctatcattg
   126601 gaccgtcttc aacatctgat caaaacatca gaaatttggt aaatatcaat ccttccaatc
   126661 gaggaatggg tggacaagtc tatggttcag atggcgtagc gccaacctta acaggtgatg
   126721 aaggaatcaa aatcgcactg ccagcaaggg atggaatctc tgtagcagga ctattaccgg
   126781 gaaagtttga acaaggtaat cgagtttatg aagttactgg aaccgccccc accttgtcaa
   126841 cgaaacaagg tggtacaaaa atcatgattc gaaaaaatga aacagaatat caagaggtga
   126901 agccagaaga cagtgtgaat ctggcttttc ctaattccac aagtcgccga ggtcgtctgg
   126961 gaaaacagag tgttcatacc ttactaacag gagaccaaca agcgatcgtc acggatcagt
   127021 atcaaattcg gaagctaaca cctagagagt gttggcgact tcagggcttt cccgattggg
   127081 cttttgatcg agattctcaa gtcaattcag atagtcagtt gtataagcaa gccggaaact
   127141 ctgtaacagt tccggtcatt tttgatattg ccagaagatt aaaagagttg gatgtacatg
   127201 gtttatgatg agttgattgg agaaatttat tgggtgattg gaaagattca gtcagaccca
   127261 gaattagaag aacaattgcg acggttaaaa tttgatattc gcaagaatgg tgtcaaagtc
   127321 gctggcgatc catatttaat gaatgaggag acggatgctc gaattgaaat aaatcaagta
   127381 attgcagaat ttgagcggat tgcggaccaa gcaaaagaac cagatattcg tcaatacttg
   127441 ttagaaatga aagcagagtt ggaagtaaat ggtattacag atgagtaacc taaaccaaca
   127501 caactgactg ttaggcgctg accgcggagg attcgcgaag cagaaatcct ccgtggtgct
   127561 gtgcctgttc atggacggcg ttagccgacc atgatgtctc acccccgtat ctaacagggg
   127621 ggtacaaaaa cacaaaaaat aagtaagcaa ccattaagaa tgcttgttgt atcaaagata
   127681 gtaagtaatt tgtataggtg ttaactcatt tgaaaaagtt aacaccttga atttggaggt
   127741 gagaacttgg cacaacggaa tttagattat cggctattaa aagaccgacg caacgaatac
   127801 ggcgtttcac aaaataaatt ggctacggct tgtggactta gtcggccgta cttaaatcag
   127861 atagaaaatg gtggcgtaac cgcatctata aaaaccatga ggaaaatttt tgaccaactg
   127921 gaaagcttta atcccgattt gcctttgacg ttactgtttg actatgtaag gattcgcttt
   127981 cccacaacgg atgcacgaaa aattattcaa gaaattctcc atttgaaatt tgagtatatg
   128041 ctccatgaag attatgcctt ttactcctat caagaacagt atgtcatggg tgatattgtg
   128101 gtgatgttgt ctcatgaaga agataaaggt gtgcttttag aattaaaggg gcgaggttgc
   128161 cgacaatttg aaactttttt actcgctcaa aagcgtagct ggtacgactt tttcgaggat
   128221 tgtctaaagg ccggtggcgt gatgaaacgc ttggacttgg caatcaatga tcgagtgggg
   128281 ctattggata tacctgagct aacgaaaaaa tgtcagaagg aagaatgtat ctccttgttt
   128341 cgtaccttta aaagttatcg ttccggggaa cttttaaagg ctgatgaaaa ggacggcatg
   128401 ggcaatacct tatatatcgg cagtctcaag agtgaggttt atttctgttt gtatgaaaaa
   128461 gactatgaac aatatatcaa gttagggatt ccattagacc aaactgagac gaaaaatcgt
   128521 tttgagattc gactgaaaaa tgaccgtgct tttcatgcga ttcaagattt gttaaaaggt
   128581 cgtagcattg agagcaccac gttttccatt atcaatcgtt acttgcgatt tgcggataaa
   128641 gtagaaggta aaaggcgaac caactggccc ttgaatgaac aatgggggcg ttttattgga
   128701 cggaatcgga aagagattca attaacttcc gagccaaaac cgtataccat tgaacgaacc
   128761 ttgaattggc taggccgaca agtcgcccct acgtggaaaa tggctaagga gttggatcga
   128821 ttgaatcgga caacctatat ccaggatatg gtacagaatg cacgcttatc agaccgacat
   128881 aaaaagattt tggagcaaca aagtatggca attgaaaatt tgattatatg aaaagaggaa
   128941 tcgtcatggg aattgtaaaa gatatttttt tggtatttgg tggcagtatg cttggtgtta
   129001 ctgtgatgtg cttgatgaat gcaagtgcag cagcggatcg agcaatggaa aagaaaggaa
   129061 agtgacaaga tgaatttcgg acaaaattta tgtgcgactc gttccttagt gaaaagctaa
   129121 ggcactaata aaagaacgaa aaagtttggt tattaggaga actgataatc tgacaggtgg
   129181 aatgatgaag taacgctctg aaacgcctgc cctgagcctc cgacaagcat tgtatgagga
   129241 aactcagaat gtttgaagct cggtaaagac ggctgaaaga taccgtaata gttgatgaac
   129301 atatatcttc tatcgaaaac tatccagagg tgggtagcgt atccaacagg tcgggggtct
   129361 ataaaatatc tatggttaga atgttctata aggaactgac gaaacagcga atgtacgggt
   129421 ctaaatttga actttgtaga aatgcaaagg tacgagaaat cgtagctggt gtggcaaagt
   129481 aagaatatag gttatgaaat gccatataac gttacaggcg gtatcaagcc agcaggctta
   129541 tagctagtga cctaaggata tatatgtata gataagatta tcggaacgag gaaaggtatt
   129601 gggttctcat caagagaata aactgacgaa gaacaataag cagttgaact aatgctgaaa
   129661 agcagagggc gaacctaaga aattcttgta atgagaatgg aggaatgccc tcaagtcgtg
   129721 tatatattag aaaagtatta tgttgtttca ataaggatta cgagtaagat aaaaaagctc
   129781 actcaatttc aagtaaagga gtgaagcctt atgcctaaaa ataaaaatga aacattgtgt
   129841 gtagaagatt taagacacgc tgaatattac gaaatgcaaa acacctttga tgatttatat
   129901 gccaaaagta agaatggaga tattttcact catcttatgg atattatcct atcgagagaa
   129961 aatatattac tggcatatcg aaatatcaaa gcaaatgcag gcagtaaaac agcaggaaca
   130021 gacggtacaa taattaaaga tattggcaaa ttgccagcag aaacagttgt caaaaaagta
   130081 agatacattg ttgcaggcag tccacatggg tatcgaccta agccagtgag gcgaaaagaa
   130141 ataccaaaac caaatggtaa aaccagacct ctaggtattc cttgtatgtg ggacaggctt
   130201 atacaacaat gtataaaaca agtattagaa ccaatctgcg aagctaaatt tagtgaaaac
   130261 agctatggtt ttagacctaa taggtcagtt gaaaatgcaa taaaagcaac ctataaccgc
   130321 ctacaaatca gccagctaca ttatgtgatt gaatttgata ttaagggttt ctttgacaac
   130381 gtgaaccatt ccaagctgat aaaacagata tgggctatgg gaatacggga caagcacttg
   130441 atattcattt taaaaaggat attaaaagct ccaatcaaaa tgactaacgg tacaataaca
   130501 tatccagaga aaggaactcc gcaaggggga ataatatccc cactactagc aaacattgtt
   130561 cttaatgagt tagaccattg ggtagaaagc caatggcagg aaaatcctgt tacaaaaaac
   130621 tatgtggttc atatcaataa aagcggtagc ccatgtaaaa gcaacgctta caaagaaatg
   130681 aagaaaacaa agttaaagga aatgtatatg gttcgttatg cagatgattt tagagttttc
   130741 tgccgctaca aggaaagtgc tgaaaaagcc aaaatagcaa tcactcaatg gattgaacaa
   130801 cgattaaaat tggaagtatc acaagaaaaa acaagaattg taaatgttag aaaaagatac
   130861 tccgactttc ttggtttcaa gattaaaatg ataccgagaa gaaagaagtt agttgttaaa
   130921 tcacatataa gtgataaaca attcaaaaac caaaaagaca agctggtatc acaggcaaag
   130981 aaaattgctt ctccctcaaa agggaaaacg gaattagaag aaacaagact ttataattca
   131041 atggtattag gtatgcaaaa ttattatcag attgcaacga atgtaaatct ggattgtatg
   131101 aaactgaata gagctgtaat ggctatcttc actaacagat taggtacaaa caaaaggggc
   131161 agattgagaa aaacaggcag acaacttacg acaaaggagg caacaagata tggtaaatct
   131221 aaaatgcttc ggtatgttgc tggcgagggc gaacctattt tccctgttgg atatatccaa
   131281 cacagaaaac caatggcaaa ggtgtattta gcgaattgct acactctaga gggaagaaaa
   131341 tttatccaca ccaatctaag tgttgataaa ttactgatgt accagttaat gaaattatct
   131401 ttggaaaatc gcacaataga atacgcagac aatcgaattt cgctattttc tgctcaacat
   131461 ggaaaatgtg ctataactct ggaagaattt caacaagcta atgaaataca ttgtcatcat
   131521 attgtaccaa ctggagctgg tggaaatgac gattataaaa atcttatttt ggtaaaagag
   131581 gcggtacacc gtctaataca cgctaaaaca gaagaaacaa tacaaaaata tatagctcta
   131641 ttgaagctaa ataaagtcca gctcataaga ctaaataaat atagagtatt agctggcaat
   131701 caagaattaa acttgatata ggtctactac ataaatactt ttcaatataa acacgatgga
   131761 acgcggagtg cggtgaaagt cgcacgctcc gtgtgaatgg ggggaaaagt ttgagatatt
   131821 tataatatca ggaacttacc tatccatata tcaatggttt ttaaccaatg cccaatcctt
   131881 agtcttactg gcaattgtgg tcattggttt gtttttagga tttaagcggg agttttccaa
   131941 actgattggc tttttggtga ttgctttgat tgcggtcgga ttggtcttta atgcttctgg
   132001 ggtgaaggat gtcttactca gtttgtttaa ccgaattgtc ggtgcgtaag ggggaagcac
   132061 gatggaacag atgcgtgttt atattgcgaa cctcgggaaa tataacgaag gtgaattggt
   132121 gggggcgtgg tttaccccac ctgtcgattt tgatgaagtg aaagaacgaa ttgggttaaa
   132181 tgacgaatac gaggaatatg caattcatga ttatgaactt ccctttgaga ttgatgagta
   132241 tacgccaatt gaggaaatta atcggttgtg tggcttagcg gaggaacttg aaggaacgcc
   132301 agttggtgaa gttgcttctg agattcaaca tgctttcttc aattcttttg aggagatggt
   132361 agagcatgtg gatgatatta tctattatcc agattgcgat gatatgagtg atgtagcata
   132421 tttcttgatt gtagaagctg gtgattttgg agaagtacca gaacacttga agacgtatat
   132481 tgattttgat gcgtgtggta gagacttgga gattggaggc aattatttgg taacgagtcg
   132541 aggtgttttt gagtatccat attaacaaaa ttattgaagg gtagttgatt tctaaactat
   132601 ccttcttttt aaaggaatga tttgatgaag aaaataaaaa gctacaccag tatttgggca
   132661 gttgaaaagg tcatttatgc aattaatgac tttcaactgc cttttcctgt gacttttaac
   132721 cagatggctt ggtttgtttt atccttgctg tttgtcatcg tatttgccca tgtgcctcca
   132781 ctatctatga tagagggggc ctttttaaaa tacttaggta taccggtggc agttacttgg
   132841 ttcatgtcgc aaaaaacgtt tgacggtaag aaaccattgg gatttttacg atcttttatt
   132901 agctatcact tacgatttaa ggtcactttc gcaggaaaga aagtcaaaga acagaagaaa
   132961 cgatgggacg aacccattac tctggtaagg agtgtgaact atgtacccga ttaagtatat
   133021 tgaaaataat cttgtcttta atcaagaggg agaatgtttt gcctactatg agttaatacc
   133081 ttacaattac tcctttttgt cacctgaaca gaaatatcaa gtccacgata actttcgtca
   133141 attgattgcg caaaatcgtg aaggcaagat tcatgcctta caaattgcca cagaaagtag
   133201 tattcgtgcc acgcaagaac gatcaaaaaa ggaaattacc gggcgattaa cagaagtagc
   133261 gaaacaacga attgatttac agacagaggc attagtatcc atgattggcg atagtcagat
   133321 tgattatcgc ttttttattg gcttcaaact gattgcgaca gatgaagagg tcaatctaaa
   133381 gaatctcaag aaatctttct tctccggctt tcaagaattt gtctatggag tgaatcatca
   133441 tttgatgggc gattttgttt ccttatccaa tgaagaaatt cgccgatata ccaagcttga
   133501 aaaactaatg gaaagtaaat tggctcgaag atttaaagtc agacgagtca caccgagtga
   133561 tctgatgtat ttgattgaac atatctatgg cgaaaagggt acaccatttg aagaatatga
   133621 atttcagcta ccaaagaaaa agctgaagtc ggaaactttg gtgaaacgtt acgacttatt
   133681 acgtcccagt cgttgtttga ttgaagaaaa gccccggtac ttatgcatgg aacatgagaa
   133741 tcatgaatca tatgtagcgt acttaacaat taatacaatt gtgggggaaa tggagtttcc
   133801 ctcctcagaa cttttctatt accagcaaca acaatttaca ttcccaattg acactagtat
   133861 gaatgtggag attgtgacga acaaaaaggc acttgctacc gttcgcaata agaaaaagga
   133921 attaaaagac ttggacaacc atgcctatca atctgacaat gaaacaaatt ccaatgtctt
   133981 agatgcattg gattccgtag atgaattgga aactaccttg gatcagtcca aagaatccat
   134041 gtacaaactg agctatgtgg ttcgagtaag tgccgaatca gtagatgaac taaagcgccg
   134101 gtgtgatgaa gtgctagatt tttatgatga taccaatgta aaactagtcc ggccttttgg
   134161 cgatatgatg gggctacatg aagaattctt accttctagt aagcgataca tgaatgatta
   134221 tatccagtat gttacgtctg attttctcgc cggacttggt tttggcgcca ctcagatgtt
   134281 aggggagttg gaaggcattt actttggtta taacgtagat acggggcgca atgtttacct
   134341 gaaaccggca ttggcctcac aaggggtcaa ggattcagtt accaatgcgc tagcagcggc
   134401 attcctcggt tcactcggtg gcggaaagtc ctttagtaac aatctcttag tttattacgc
   134461 cgtccttttt ggtggacaag ctgtgattgt cgatccaaaa ggggaacggg gtggctggaa
   134521 agaaaccttg ccagaaattg cggatgaaat caatattctc aacttaacta gtaagccaaa
   134581 aaatcaagga ttacttgatc cttatgtgat tatggagaaa aagaaggatt ctgaaagtct
   134641 agcaattgat attctgacct ttttaacagg aatttctagt cgagatgggg agaagtttcc
   134701 agtgttgcgt aaggccattc ggacggttac ccaaagcaat caacggggat tattacaagt
   134761 aattaatgag cttcgaaaag aaggctcacc agttgcggaa aatatcgcgg atcacatcga
   134821 gtcctttacc gattatgatt ttgcccattt gcttttctca gatggttcga ttacccagtc
   134881 gattagttta gataggcagt taaatatcat tcaagtagcg gatttggttt taccagatgc
   134941 agaaaccact tttgaagaat ataccaccat ggaattgctt agtgtttcca tgctaatcgt
   135001 catttccact tttgccttgg actttatcca tagtaatcga gaaatcttca aaattgtaga
   135061 cttagatgag gcgtggagtt ttcttcaagt agcgcaaggg aaaacattat cgaataagct
   135121 cgttcgtgct gggcgggcta tgaatgccgg ggtttacttt gtcacgcaaa atagtgatga
   135181 tttactggat gaacgcttga agaataatat cgggttgaag tttgcgtttc gcagtaccga
   135241 tattcatgaa atcaagaaaa ccttggaatt ctttggcttg gatcgagaag atgaaagcaa
   135301 tcaaaaacgc ctacgagatt tggaaaatgg ccaatgcttg atgcaggatt tgtatggtcg
   135361 ggtaggcgtg gttcaggtac atccagtctt tgaagaactc ttccatgcct ttgatacccg
   135421 tccacctgtt caagagagaa tggagtgagg ggatgaaaaa gaaacttttt cggattgtgg
   135481 gaatcgtttt tattagcata ctcactctga tagttctatt gagtttagtt ggtacggtag
   135541 ccgaggcgac agggctagtt gatgatacag ttgaagcagg aaatctatat tccaaatatt
   135601 cactgaacaa ctatcaacta gatttctttg tggatagctc ttgggattgg ttgccttgga
   135661 attggggtga tggcttaggg aaaagcgtga tgtatggtct ttatgccatt actaatttca
   135721 tttggacggt gagtttgtat ttgtcgaacg ccacgggtta tgtggttcaa gaggcttaca
   135781 aattagattt catttcggat acggctgaaa gtattggaaa gaatatccaa acattggctg
   135841 gtattactga aaatggactc cagacctccg gattttattt tgggtttcta ttattgatga
   135901 ttttagctct gggggtgtat gtggcgtata ccggattatt aaaacgagaa accacgaaag
   135961 cagttcgagc cgtgattaat tttgtgatga tttttctact atcgggttcg ttcattgctt
   136021 atgcgcctac ctatatcaca aaaatcaatg actttagctc agatgttagt gaagcggccc
   136081 ttacccttgg aaccgagatc gttgtaccca attcagaaag ccaaggaaaa gatagtgtgg
   136141 atttgattcg ggatagtttg ttttcgattc aagtccaaca accttggtta ctactgcaat
   136201 ttgatgattc caacatagaa gaaattggtg aagaccgggt caacaagatt ctatctgtga
   136261 gtccagatga aaacaaaggc aaagatcggg aagaagcggt caaggcagag attgaagaca
   136321 atgacaatgc gaatctcagt attaccaaga ccatgaaccg tttagggacc gtggtctttt
   136381 tggtattgtt caatattggc atttccttct ttgtttttct tctaacaggg attatgttgt
   136441 tctcgcaaat tctcttcatt atctttgcga tgtttctgcc aattagtttc ttattgtcca
   136501 tgttgccgac ttatgaaagt ttaggaaaga aggcgattat tcgtttattc aatacgatta
   136561 tgatgcgagc gggtgttact ttggtgatta cgactgcatt tagcatctcc acgatgtttt
   136621 tcaatatttc ggcaacctat ccatttttca tggttgcttt tctgcaaatt gtgacctttg
   136681 ccggtatcta tttcaaattg ggcgacatta tgagtatgtt caacctccag agtaatgata
   136741 gccagtcaat gggaagacgc gtcatgcgaa aaccgcaaat gttaatgaat cgaaaattgc
   136801 ggcaactcaa tcgaaatgtg ggacgagctt tggcttttgg tggtggtgca gcagtcggaa
   136861 ataagttggc aaaggaacaa tcaaaatcca aatttaagcc atccggttct tctctacgaa
   136921 agaattcacg attaccgaac gatcacgaaa tactatctga cttaactaag gagaatccag
   136981 tttcaaataa taagaaacaa tcccgaatga atttggctgg gagaaaaatc ggcaaagttt
   137041 tggataccca agctttggtg aaagataaga ctaaacaagt aaaggatcag gtaaggaata
   137101 cgccaacgaa tttgaaatac aatctccata aaggaatcga aaagtcgaaa aaagcaccag
   137161 aagaattcaa gcgcggactg ttccaagaaa aagcggatcg agtggatttg cgagaaaaac
   137221 aacgacaacg aagaaatgcg aaaatggacg aaaaacgcaa gatactgagt gaagcaacaa
   137281 atcgtcaggg aaaaagaagg gcgaatattc caatagataa agcagctcaa cctcagaaag
   137341 atatgatgct gaaaaaagaa gcaccaaagc ggattgtgag agcaaatctg aatcccgaaa
   137401 tcaaacgaaa actaactagt caagaaatca tttcaaaagg gaaaagccaa tcagcaagta
   137461 agaaaaattc tttccaacaa gtgaaacaga ggtccactct gccaaagcag accaatcaaa
   137521 aagtacaaaa aagaatgaac catcgtccaa aatcaaggtc aggtgagaaa aaatgaactt
   137581 gaagaaagtg ggtgttattt cattaacttt tctgaccatc tcttttatgg gtattttgat
   137641 gtgtgtgggt ttgttgtttg gtgaagacag tgagggaaat ggtagttctg gcacttctcc
   137701 tggcggaact agtgtctcag aagaagtatt gaaacaccgt gcaatggtgg aaaagtatgc
   137761 caaagaatcg gatataacag agtatattcc aattcttttg gcgattattc aagtggaatc
   137821 tggtggcaca atggaagacg ttatgcaaag ttctgagtca gccggattac cacctaattc
   137881 attaagtacc gaggcatcca tcaaacaagg ctgtctctat tttgcgtctt tggttaagcg
   137941 ttccaaagaa ctagggtgtg atcaagatag tattattcag gcctataact atggtggcgg
   138001 gtatctagat catgtcggga aaaacgggaa gaagcatagt tttgctttag ctgaatcttt
   138061 ttcaaaggaa aaatcaggtg gtcaaaaagt cgattacccc aacccaatcg cgattaagga
   138121 aaatggtggg tggcggtata attatggcaa tatgttttac tgtttattag tgaagcaata
   138181 cctaactaca acccagtttg atgacaaaat agtccaagaa atttttgatg aggcatttaa
   138241 gtatgaagga acggcctatg tgtttggtgg ctcaagtcca gaaacggggt ttgattgtag
   138301 tggcttgacc caatggtgtt atgccaaagt tgacctgaaa cttcctcggg tggctcagga
   138361 tcaatatgat gccatgactc atattgatct aaaagatgcc aaaccaggtg atttagtttt
   138421 ctttcattca acctatgatg ccggtactta tgtgacccat gtgggcattt acgcagggga
   138481 gaatcgcatg tttcatgcag gagatccagt ggggtggacg aatctaacgg aaaactattg
   138541 gcggcagcat cttatcggag ctggccgata caaataagag aaaagaggaa aaagaatgaa
   138601 gataaaaatt gaacggaatc aaaaggaaaa gagcccaaaa aagaaaaaag aacgagttgt
   138661 atccgtgggt aagcatcgaa aaatggtgct tgccctttgg cttttattgt cttgtagtct
   138721 tgcttttggc gtttataaaa atttcaccgc cattgatcaa catacaactc atgaaaaagt
   138781 ggttataaaa gagaaggtag tgaatacttc tggcgttgaa agttttacag aggattttgc
   138841 gaaagaatat ttttcatgga aaaataacaa agaagcaatt gaaaagagaa tgagtaatct
   138901 cgaacagtac cttacagaaa acggtctcgc tttaatccaa gatatggttc gagcagatat
   138961 tcccacgagt tccgaagttc aatctgtaaa aattctagat gttgaaaaac actcggaaga
   139021 atttgtcgtt tcatttttag tggagcaaca tattacagag ggaaaaaaga cgcaatcaat
   139081 ttcttctgca tatcgagtga caatctttga agatgaaaac aggaatcatt tagtaactag
   139141 tttgccaaca atgattggaa agccagacaa ggcaaaatat gaagcaaaac aagtagaaaa
   139201 cgattcagaa attgatgcca aaacaacgga agaaatcacc gattttttag aaacattttt
   139261 taaactttat ccatcagctt ctgaaaaaga attggagtat tatgttgaaa atggtgcgat
   139321 gcgaccaatc aatattgact taaagttttc ggagttagag aatccagttt atctacaaaa
   139381 cggaaaaaat tttctagtga gtacaaagat aaaatacctt gataatgtat caaaaaccac
   139441 tagctacttt cagtacaaat tagtattaca aaaaaatgga aactggaaaa tcgttgatgt
   139501 taaataataa tgactcaatc taattttatt agaagttata agtagtgtaa cttatttcag
   139561 gcagaagtcg cccatcctct ataggtgggt gatgaatgcc attcggtaac tcgaaaaccg
   139621 acaattaaga catagtgcct ttttatttta atccatgtca taatcagtct atataggaaa
   139681 tggttgatat accatggaat tagatacaaa taatcattca gtttttcttc ttggttaccc
   139741 ccttatttta gtagtgaaac attgtaaaca tgtcattgat gatgtaatgt cagcttatgc
   139801 aaaaactgcc tttgaaagaa tttcagaatc acatcacatt accttagatg aatgaaatcg
   139861 tgataaagaa tactttcata ttatgctcaa agcacaacct aaaaccgaat taacaaaatt
   139921 cagcaatgcc taagctcacg tctgataaaa tgagactttc taagggtcaa aaatttcctt
   139981 tgaatacgat tattgcttag ataaaagtaa aagccttaga actacgggga tagcttggtt
   140041 aataagagat atcgttgtta gtaaagacat aggcttgcaa gtatgctcta ttcccaagaa
   140101 tctccccctt caagcaccaa ggatcgttaa attcagctaa gtggcaagta attcactaga
   140161 cgataattat ctccatattt caatctcagc ttttccattt ttcatagcaa attccgttat
   140221 ttttatagca tctaaaagat tcagcttttc cactgatctt tcaccacttt tcagcttttt
   140281 tattgtgctt aaattgatac cagtaccttt tgatattgaa ttggaagtaa aatcattaag
   140341 ggtttttttt attaaattca tatccgcaat tccagcgttc ataagaatga agattctcct
   140401 ctcatagact actttgaaaa tggtactaca gtggctgttt atatatttca gtaggttact
   140461 gtagtggtca tcttattata attagaaaag gaacctaaat caaaaatgct aaagaaaatt
   140521 ttcatagtat taagcctctc atgactaaag ccacggaatt cttgataaaa gagtatactt
   140581 gcaagcctaa acagcggtat ctcttattaa ccaagctatc cccgttgttc ctaaggttct
   140641 tgatgttttc taaggcaatg cttgtattca tagcccttgg tcaaaatatt gatactatcg
   140701 ttgacgtttc gattatgatg tatacggcaa ataggacaag tccattctcg aattgtgagt
   140761 gacttcttac catctgtgtg tctacattct gaaccaattt gactagacgg aaatcattta
   140821 tctatcttaa tgattttttg acagaagtat cgaaaatctt tacataatct gggtgatgta
   140881 ttcttatgca gatgagagcg ttggctccgt attcataacc agtagcctct aaaacgtagt
   140941 ccatcggtgg gatacctagc ttgcggttgc cagcggcttt cgcagtcttc ttgtgatcaa
   141001 atcaagcatc tcattgagca ctagtatttt gaagataata cttgagtttt tcggctttta
   141061 gaagttcact tcatcttcca tcatccatgg aaatcccact cacccatacg caggcctcca
   141121 aaaattcttc aacagtggtt ttttcagaca tttttctgaa tacctccttg ttttttgata
   141181 cgccagatag tcaggaaaaa ggcaacaaaa cacaaaacaa agctgcctaa aaaggtaatc
   141241 ttcattccat ataaaaagac atccggccga tttgcgatat agttagttac ttgctggccc
   141301 atcttagcag acatcgcttg atataagacc gtcgtagaaa gcgaaatccc gctgaccatc
   141361 cccaaatttc gggcaaagga attcatcgag cctgccagtc ccaagttttc gatagtgacc
   141421 gagctcataa ccatcgtatt attgggggac tggaacaagg cattgccggc acccatgatg
   141481 gcagtagcga caatgtatag ccacaaagga gagtccactg acaaaaacat atacatgacc
   141541 tgggttaccg acaataagcc caagcctact aataccaaaa tctccgggcc aacccggtcg
   141601 gtcaggtagc cgcttaaagg cgccccgacg accatcatca aaggaaagac catcatcaac
   141661 agcccagcat agctaggact caacccgcga gcattttgca gataaaaagg aatcactaca
   141721 ttgacaaaga agttggaaga aaaaatcaac aaggctgtaa tcaagctcat ggtaaaaatc
   141781 ttgttcttaa aaataccgaa agaaatcaat ggagaggctg ctttcttttc aacttttaaa
   141841 aagctgacaa aggcaatcac tgaaattacg aacagtacaa gggggactgg atggaaaaag
   141901 ccactttctt gccccaaaaa gattgctcca aaaaagctga taatcgtagc cgcaatggca
   141961 gcaaagcccc ctccatcgat tgtatggccg ctcatggtga tatcttttgg taagaatttt
   142021 tcagcaatca acatcgttac gattcccacc ggtacattga tccaaaaaat gtacgcccaa
   142081 gaaaattggg acaaaatcaa gccgccaaga cctggtccag caatcgagcc taatgaaaca
   142141 aacgcaccta ttgctcccaa tgcccgacca cgttcatgta tgggaaagac ttccgtgatg
   142201 attccggcat ttgtagccat agtcatacta gcaccaatgg cttgtaccac ccgtgcgaac
   142261 aataaaatac ctagcgaatg attgaaccca cacaacagcg atcccaagac aaagatcagc
   142321 gtaccaatcc gaaatacttt gattttccca cggctatcgc caattttacc aaacagcaac
   142381 aaacaagaac agacaatcat cagataaacg gacactaccc attccgcttg attcattggt
   142441 atgcccatat catctgagat ggtaggtagt gcaatattga caatactgcc atccaatgtg
   142501 gacatgaagg taaacataga tatagcaatc aaaatccacc agcgattttt ttggactttt
   142561 gcatcttctt gataactata cataatagga tttcctttct aatgatcgtg tagctaagaa
   142621 caatataacc tatgtctact gcccaacaac ttctcgcgac tctagccata ggaagcttga
   142681 gtaatttcga tttgatatcc tcatgtaacc atgtaagttg gagatgcttt atttgaactt
   142741 actctatagt aactagtgat aattcgcttt actttcttct agcaatttct aaaagtcgac
   142801 ttcattgttc ttcagattaa tagtgtgagc tatctcgtga gacgtaagca aatttccatt
   142861 ctactttttc ccaatttttt catatttatg gtgttgcacc tatttgtttt ccaatttgct
   142921 tttcaaatac attgctatga tattcaattc cataggatta tactaaatat caatagtatg
   142981 aataatatat tatagatgtt tatatatcac tgttaattat tatccacaat aattaatgat
   143041 tacctcgata tttgtcaatc aaaggttgaa acaatttatt ttcagcatct tttctagctt
   143101 gagctgcact cttaatagaa tcatacgatc ctaaatagta cctctttttt tttaaagtta
   143161 tatacgcaat ctatttctct ttagaacgat aaactccctt aacaccactt gtattatttt
   143221 tcggtaattt tgacgttaga cactctatta ctgtcccttc aacacatgtc cttgtttctt
   143281 gcctttttaa acatccacaa ctttgagtat gtccaaaaaa taagttacta taacttatct
   143341 cacacatact gccacactca caatgacaaa cccattttgt tttccatgaa cagttattgt
   143401 ccaaaggata ctttgcagta agtaatccga attttttatt ttcaatgtga tgcttttttg
   143461 atttcaaaca tccacagctt tttacatcac cttttagaag tcgctttgcc gatactaact
   143521 tttttctccc acacagacat tgacattccc aaacaacagt tccttcactt cgcagtttag
   143581 ttggcttgat tgcaactaac ttaccaaaag ttttatttgt caaattttta tatttatgcc
   143641 tatttttata atttccacat ccacaacttt tggttctacc tgttagtaag tttgatcgat
   143701 atacaatcgt ttcattccca cagtcacata ggcaacgata ttttttatat ccattatgag
   143761 taatctcctc aacaacagta aggtgaccat atctttcctt cactgcacct accctcccaa
   143821 gaaagaagta ccatataatt tcaattaact tttaataaat cagaaaaaaa tatttccaat
   143881 ttttcttagt ctgattttat gactaattta caatacaaga ctgaacgata cgtacacgaa
   143941 atcctcaaga tagataaatt gttttcatct agtgaaacct gctcaaaata tgagcataaa
   144001 gacggcaata atacactcga tattcgataa tggacttgtt ttatttgtca aacccatcgt
   144061 aatcgagata tcaattccag tctcaatatc ctgatcaaag gtctaagaat ccaaccattt
   144121 tcttgttact ttgtcagatt gattaccttt tttagtctcc gaataataag gttttcggat
   144181 caactaacat gctctgagaa agactactat ctttgcaaat ttccaaatga aggtgtgggc
   144241 cagtactatt cccagtactt cctacatagc caattatttg tccttgcaaa acattatctc
   144301 cagtttttac taggtattgt tgctggtgag catataacgc ggttgatcca tcttcgtgtt
   144361 gtatcaccac gtaatttccc caagagtagt gaaactctgc tttaacaacc ttaccagctt
   144421 taactgcatg aatcggctca ccctgtgtag ctgccatatc aagtcctcgg tgaaattcat
   144481 ttccacgatt tccaaacaaa ctggttattg aataattatg aataggcact tggtatccag
   144541 tcttactcat ttgtggacct ttaacttctt tatcatagtt ggttaaatcg taggttttaa
   144601 ttaattcatt tagcttcaaa tagtattgtg tatctgttgc ataccgtcct gtaaggaatt
   144661 tagttgcttc tcgatatgtt ttactattag cttttaatgc tcctgcataa aaatctttat
   144721 ttccactaat tcccttagtt aataatttgg cataatcttc aaagctttcc tcatagtttt
   144781 catacactct aaattttgat tgggtcgtat aaagcgttcc attacccaaa tcttcgtttg
   144841 ttaccataat gacaaagttt ccattataag ttccttttat cccaaataaa ttgtaattcg
   144901 gtgcctgagc taactggctt tgaccactgg cagattctaa gatcgcttgt gcaatcataa
   144961 cagaagcata taaatcatat ttctgaccaa tttttctcgc agactcacca attttcataa
   145021 taaaattttc tacagattca tttttgtcaa aatgaatttc ttcattacca gatagtattg
   145081 gttgtgattg gaaagattct gttgattcta tttgctgtgg tgtcgaaaaa gtttttgttt
   145141 gtccttccgt ttttggcgct tccttttttg aagattctat atggtttggt tttgtcactt
   145201 tcgaagaagt tatttcactt gtactacttg aagttgttga agattcggta cttgaaatcg
   145261 tactactttc acttgacgaa gttgttgaag actcggcatt tgaagtcgta ctactttcac
   145321 ttgatgaagt tgttgaagac tcggcatttg aagtcgtact actttcactt gatgaagttg
   145381 ttgaagactc ggcatttgaa gtcgtactac tttcacttga tgaagttgtc aaaagttcac
   145441 tactctctgc tgttacatcg gaattactca tttcagtcgt ctcggttctt tcttttgcaa
   145501 ttttgtatgt tgaattttcg cttgccaaca catggaaagg tgttgctata aggagttggg
   145561 acattaatat aactgctgat gcaagtttta aagatttttt catttgattt acctctcttt
   145621 tttctcttta atagtgtttt ctattaaaaa ttatgataaa tattttcaat gaattgagta
   145681 atacagtata tttcttgatt tcatttagta acgattatgt ttcaatgttt aatcctgtta
   145741 ctgccttta
//
LOCUS       DAFELK010000002       137394 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFELK010000002
VERSION     DAFELK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 137394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 137394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..137394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.002"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            212..604
                     /locus_tag="LP433_000134"
     CDS             212..604
                     /locus_tag="LP433_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2004333.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="LP433_000135"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="LP433_000135"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBL2004334.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="LP433_000136"
     CDS             3165..4775
                     /locus_tag="LP433_000136"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBL2004335.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="LP433_000137"
     CDS             5067..5936
                     /locus_tag="LP433_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBL2004336.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="LP433_000138"
     CDS             6101..7372
                     /locus_tag="LP433_000138"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL2004337.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="LP433_000139"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="LP433_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBL2004338.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="LP433_000140"
     CDS             8763..9026
                     /locus_tag="LP433_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBL2004339.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="LP433_000141"
     CDS             9471..9920
                     /locus_tag="LP433_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2004340.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="LP433_000142"
     CDS             9977..11395
                     /locus_tag="LP433_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2004341.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="LP433_000143"
     CDS             11395..12255
                     /locus_tag="LP433_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBL2004342.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="LP433_000144"
     CDS             12429..13202
                     /locus_tag="LP433_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2004343.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="LP433_000145"
     CDS             13349..13714
                     /locus_tag="LP433_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBL2004344.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="LP433_000146"
     CDS             complement(13862..15070)
                     /locus_tag="LP433_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2004345.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="LP433_000147"
     CDS             complement(15089..15367)
                     /locus_tag="LP433_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004346.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="LP433_000148"
     CDS             15521..16216
                     /locus_tag="LP433_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2004347.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="LP433_000149"
     CDS             complement(16658..17455)
                     /locus_tag="LP433_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBL2004348.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="LP433_000150"
     CDS             complement(17452..18636)
                     /locus_tag="LP433_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL2004349.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="LP433_000151"
     CDS             complement(18661..19908)
                     /locus_tag="LP433_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL2004350.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="LP433_000152"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="LP433_000152"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBL2004351.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="LP433_000153"
     CDS             21888..22202
                     /locus_tag="LP433_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBL2004352.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="LP433_000154"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="LP433_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBL2004353.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="LP433_000155"
     CDS             22887..23531
                     /locus_tag="LP433_000155"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBL2004354.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="LP433_000156"
     CDS             23546..23875
                     /locus_tag="LP433_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBL2004355.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="LP433_000157"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="LP433_000157"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBL2004356.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="LP433_000158"
     CDS             24863..25687
                     /locus_tag="LP433_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBL2004357.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="LP433_000159"
     CDS             25680..26027
                     /locus_tag="LP433_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBL2004358.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="LP433_000160"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="LP433_000160"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBL2004359.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="LP433_000161"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="LP433_000161"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBL2004360.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="LP433_000162"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="LP433_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBL2004361.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="LP433_000163"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="LP433_000163"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBL2004362.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="LP433_000164"
     CDS             31657..32451
                     /locus_tag="LP433_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004363.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="LP433_000165"
     CDS             32441..34483
                     /locus_tag="LP433_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004364.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="LP433_000166"
     CDS             34764..34913
                     /locus_tag="LP433_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBL2004365.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="LP433_000167"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="LP433_000167"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBL2004366.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="LP433_000168"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="LP433_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBL2004367.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="LP433_000169"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="LP433_000169"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBL2004368.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="LP433_000170"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="LP433_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBL2004369.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="LP433_000171"
     CDS             39330..40412
                     /locus_tag="LP433_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBL2004370.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="LP433_000172"
     CDS             40412..41215
                     /locus_tag="LP433_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL2004371.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="LP433_000173"
     CDS             41285..42025
                     /locus_tag="LP433_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2004372.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="LP433_000174"
     CDS             42036..43040
                     /locus_tag="LP433_000174"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBL2004373.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="LP433_000175"
     CDS             complement(43085..44929)
                     /locus_tag="LP433_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004374.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45141..45659
                     /locus_tag="LP433_000176"
     CDS             45141..45659
                     /locus_tag="LP433_000176"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL2004375.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45787..46470
                     /locus_tag="LP433_000177"
     CDS             45787..46470
                     /locus_tag="LP433_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBL2004376.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46779..46852
                     /locus_tag="LP433_000178"
     tRNA            46779..46852
                     /locus_tag="LP433_000178"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46813..46815,aa:Arg,seq:tct)
     gene            47011..47370
                     /locus_tag="LP433_000179"
     CDS             47011..47370
                     /locus_tag="LP433_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBL2004377.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47493..49124
                     /locus_tag="LP433_000180"
     CDS             47493..49124
                     /locus_tag="LP433_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBL2004378.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49186..49827)
                     /locus_tag="LP433_000181"
     CDS             complement(49186..49827)
                     /locus_tag="LP433_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL2004379.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50013..50089
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50109..50417
                     /gene="rplU"
                     /locus_tag="LP433_000182"
     CDS             50109..50417
                     /gene="rplU"
                     /locus_tag="LP433_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBL2004380.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50444..50788
                     /locus_tag="LP433_000183"
     CDS             50444..50788
                     /locus_tag="LP433_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBL2004381.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50801..51094
                     /gene="rpmA"
                     /locus_tag="LP433_000184"
     CDS             50801..51094
                     /gene="rpmA"
                     /locus_tag="LP433_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBL2004382.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51528..54335
                     /locus_tag="LP433_000185"
     CDS             51528..54335
                     /locus_tag="LP433_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2004383.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            54526..55017
                     /locus_tag="LP433_000186"
     CDS             54526..55017
                     /locus_tag="LP433_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2004384.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55120..56109
                     /gene="manX"
                     /locus_tag="LP433_000187"
     CDS             55120..56109
                     /gene="manX"
                     /locus_tag="LP433_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBL2004385.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56142..56945
                     /locus_tag="LP433_000188"
     CDS             56142..56945
                     /locus_tag="LP433_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBL2004386.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56966..57880
                     /locus_tag="LP433_000189"
     CDS             56966..57880
                     /locus_tag="LP433_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBL2004387.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVERWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            57963..58337
                     /locus_tag="LP433_000190"
     CDS             57963..58337
                     /locus_tag="LP433_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBL2004388.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58476..58721
                     /locus_tag="LP433_000191"
     CDS             58476..58721
                     /locus_tag="LP433_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2004389.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            58893..59957
                     /locus_tag="LP433_000192"
     CDS             58893..59957
                     /locus_tag="LP433_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL2004390.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60203..60628
                     /locus_tag="LP433_000193"
     CDS             60203..60628
                     /locus_tag="LP433_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2004391.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60621..61070
                     /gene="nusB"
                     /locus_tag="LP433_000194"
     CDS             60621..61070
                     /gene="nusB"
                     /locus_tag="LP433_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBL2004392.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61167..62021
                     /locus_tag="LP433_000195"
     CDS             61167..62021
                     /locus_tag="LP433_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBL2004393.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62022..63359
                     /locus_tag="LP433_000196"
     CDS             62022..63359
                     /locus_tag="LP433_000196"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBL2004394.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63364..63588
                     /locus_tag="LP433_000197"
     CDS             63364..63588
                     /locus_tag="LP433_000197"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBL2004395.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63590..64480
                     /locus_tag="LP433_000198"
     CDS             63590..64480
                     /locus_tag="LP433_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL2004396.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64489..65307
                     /locus_tag="LP433_000199"
     CDS             64489..65307
                     /locus_tag="LP433_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBL2004397.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65414..65863
                     /locus_tag="LP433_000200"
     CDS             65414..65863
                     /locus_tag="LP433_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL2004398.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            65881..67563
                     /gene="recN"
                     /locus_tag="LP433_000201"
     CDS             65881..67563
                     /gene="recN"
                     /locus_tag="LP433_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBL2004399.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67618..67734)
                     /locus_tag="LP433_000202"
     CDS             complement(67618..67734)
                     /locus_tag="LP433_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBL2004400.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67807..68763)
                     /locus_tag="LP433_000203"
     CDS             complement(67807..68763)
                     /locus_tag="LP433_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL2004401.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            68934..69302
                     /locus_tag="LP433_000204"
     CDS             68934..69302
                     /locus_tag="LP433_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBL2004402.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            69472..69903
                     /gene="mraZ"
                     /locus_tag="LP433_000205"
     CDS             69472..69903
                     /gene="mraZ"
                     /locus_tag="LP433_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBL2004403.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            69924..70883
                     /gene="rsmH"
                     /locus_tag="LP433_000206"
     CDS             69924..70883
                     /gene="rsmH"
                     /locus_tag="LP433_000206"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBL2004404.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            70888..71289
                     /gene="ftsL"
                     /locus_tag="LP433_000207"
     CDS             70888..71289
                     /gene="ftsL"
                     /locus_tag="LP433_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBL2004405.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            71290..73482
                     /locus_tag="LP433_000208"
     CDS             71290..73482
                     /locus_tag="LP433_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL2004406.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGMFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            73508..74470
                     /locus_tag="LP433_000209"
     CDS             73508..74470
                     /locus_tag="LP433_000209"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBL2004407.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            74484..75845
                     /locus_tag="LP433_000210"
     CDS             74484..75845
                     /locus_tag="LP433_000210"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBL2004408.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYRHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            75871..76959
                     /gene="murG"
                     /locus_tag="LP433_000211"
     CDS             75871..76959
                     /gene="murG"
                     /locus_tag="LP433_000211"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBL2004409.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            76974..78194
                     /locus_tag="LP433_000212"
     CDS             76974..78194
                     /locus_tag="LP433_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBL2004410.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            78350..79675
                     /gene="ftsA"
                     /locus_tag="LP433_000213"
     CDS             78350..79675
                     /gene="ftsA"
                     /locus_tag="LP433_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBL2004411.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            79698..80939
                     /gene="ftsZ"
                     /locus_tag="LP433_000214"
     CDS             79698..80939
                     /gene="ftsZ"
                     /locus_tag="LP433_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBL2004412.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            80956..81633
                     /locus_tag="LP433_000215"
     CDS             80956..81633
                     /locus_tag="LP433_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBL2004413.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            81647..82246
                     /locus_tag="LP433_000216"
     CDS             81647..82246
                     /locus_tag="LP433_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBL2004414.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            82261..82548
                     /locus_tag="LP433_000217"
     CDS             82261..82548
                     /locus_tag="LP433_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBL2004415.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            82597..83379
                     /locus_tag="LP433_000218"
     CDS             82597..83379
                     /locus_tag="LP433_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBL2004416.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            83400..84107
                     /locus_tag="LP433_000219"
     CDS             83400..84107
                     /locus_tag="LP433_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBL2004417.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            84369..87167
                     /gene="ileS"
                     /locus_tag="LP433_000220"
     CDS             84369..87167
                     /gene="ileS"
                     /locus_tag="LP433_000220"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBL2004418.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(87216..88742)
                     /locus_tag="LP433_000221"
     CDS             complement(87216..88742)
                     /locus_tag="LP433_000221"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBL2004419.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(88757..89404)
                     /locus_tag="LP433_000222"
     CDS             complement(88757..89404)
                     /locus_tag="LP433_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBL2004420.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(89588..89917)
                     /locus_tag="LP433_000223"
     CDS             complement(89588..89917)
                     /locus_tag="LP433_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBL2004421.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            90094..90822
                     /gene="sfsA"
                     /locus_tag="LP433_000224"
     CDS             90094..90822
                     /gene="sfsA"
                     /locus_tag="LP433_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBL2004422.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            90838..91851
                     /locus_tag="LP433_000225"
     CDS             90838..91851
                     /locus_tag="LP433_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2004423.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            91851..93128
                     /locus_tag="LP433_000226"
     CDS             91851..93128
                     /locus_tag="LP433_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL2004424.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            93191..95893
                     /locus_tag="LP433_000227"
     CDS             93191..95893
                     /locus_tag="LP433_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2004425.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            96045..96362
                     /locus_tag="LP433_000228"
     CDS             96045..96362
                     /locus_tag="LP433_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2004426.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            96392..96712
                     /locus_tag="LP433_000229"
     CDS             96392..96712
                     /locus_tag="LP433_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2004427.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            96820..98280
                     /locus_tag="LP433_000230"
     CDS             96820..98280
                     /locus_tag="LP433_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2004428.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            98348..98569
                     /locus_tag="LP433_000231"
     CDS             98348..98569
                     /locus_tag="LP433_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004429.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            98600..98782
                     /locus_tag="LP433_000232"
     CDS             98600..98782
                     /locus_tag="LP433_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBL2004430.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            98782..99195
                     /locus_tag="LP433_000233"
     CDS             98782..99195
                     /locus_tag="LP433_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBL2004431.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            99318..100499
                     /locus_tag="LP433_000234"
     CDS             99318..100499
                     /locus_tag="LP433_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2004432.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(100570..100734)
                     /locus_tag="LP433_000235"
     CDS             complement(100570..100734)
                     /locus_tag="LP433_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004433.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            100888..100961
                     /locus_tag="LP433_000236"
     tRNA            100888..100961
                     /locus_tag="LP433_000236"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100922..100924,aa:Arg,seq:cct)
     gene            complement(101030..102169)
                     /locus_tag="LP433_000237"
     CDS             complement(101030..102169)
                     /locus_tag="LP433_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2004434.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(102468..103103)
                     /locus_tag="LP433_000238"
     CDS             complement(102468..103103)
                     /locus_tag="LP433_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004435.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(103216..103851)
                     /locus_tag="LP433_000239"
     CDS             complement(103216..103851)
                     /locus_tag="LP433_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBL2004436.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(103885..104346)
                     /locus_tag="LP433_000240"
     CDS             complement(103885..104346)
                     /locus_tag="LP433_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBL2004437.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(104476..104907)
                     /locus_tag="LP433_000241"
     CDS             complement(104476..104907)
                     /locus_tag="LP433_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL2004438.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(104925..105245)
                     /locus_tag="LP433_000242"
     CDS             complement(104925..105245)
                     /locus_tag="LP433_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2004439.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            105544..106320
                     /locus_tag="LP433_000243"
     CDS             105544..106320
                     /locus_tag="LP433_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL2004440.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            106335..106538
                     /locus_tag="LP433_000244"
     CDS             106335..106538
                     /locus_tag="LP433_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004441.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            106554..106892
                     /locus_tag="LP433_000245"
     CDS             106554..106892
                     /locus_tag="LP433_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBL2004442.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            106879..107058
                     /locus_tag="LP433_000246"
     CDS             106879..107058
                     /locus_tag="LP433_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004443.1"
                     /translation="MGKFNRALVFSAPLIIYALELWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(107101..107571)
                     /locus_tag="LP433_000247"
     CDS             complement(107101..107571)
                     /locus_tag="LP433_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004444.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            107658..108356
                     /locus_tag="LP433_000248"
     CDS             107658..108356
                     /locus_tag="LP433_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBL2004445.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            108534..108875
                     /locus_tag="LP433_000249"
     CDS             108534..108875
                     /locus_tag="LP433_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004446.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            108868..109539
                     /locus_tag="LP433_000250"
     CDS             108868..109539
                     /locus_tag="LP433_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBL2004447.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            109545..110231
                     /locus_tag="LP433_000251"
     CDS             109545..110231
                     /locus_tag="LP433_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004448.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            110234..110983
                     /locus_tag="LP433_000252"
     CDS             110234..110983
                     /locus_tag="LP433_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004449.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            110995..111264
                     /locus_tag="LP433_000253"
     CDS             110995..111264
                     /locus_tag="LP433_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004450.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            111269..111433
                     /locus_tag="LP433_000254"
     CDS             111269..111433
                     /locus_tag="LP433_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004451.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            111426..111728
                     /locus_tag="LP433_000255"
     CDS             111426..111728
                     /locus_tag="LP433_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004452.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            111725..111886
                     /locus_tag="LP433_000256"
     CDS             111725..111886
                     /locus_tag="LP433_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL2004453.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            111883..112188
                     /locus_tag="LP433_000257"
     CDS             111883..112188
                     /locus_tag="LP433_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004454.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            112188..112544
                     /locus_tag="LP433_000258"
     CDS             112188..112544
                     /locus_tag="LP433_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBL2004455.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            112531..112749
                     /locus_tag="LP433_000259"
     CDS             112531..112749
                     /locus_tag="LP433_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004456.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            112746..113165
                     /locus_tag="LP433_000260"
     CDS             112746..113165
                     /locus_tag="LP433_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBL2004457.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            113162..113719
                     /locus_tag="LP433_000261"
     CDS             113162..113719
                     /locus_tag="LP433_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HBL2004458.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            113716..114012
                     /locus_tag="LP433_000262"
     CDS             113716..114012
                     /locus_tag="LP433_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004459.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            114089..114502
                     /locus_tag="LP433_000263"
     CDS             114089..114502
                     /locus_tag="LP433_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBL2004460.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            114811..114963
                     /locus_tag="LP433_000264"
     CDS             114811..114963
                     /locus_tag="LP433_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004461.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(114960..115235)
                     /locus_tag="LP433_000265"
     CDS             complement(114960..115235)
                     /locus_tag="LP433_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004462.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            115689..115895
                     /locus_tag="LP433_000266"
     CDS             115689..115895
                     /locus_tag="LP433_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004463.1"
                     /translation="MLGQCFGNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
     gene            116091..116258
                     /locus_tag="LP433_000267"
     CDS             116091..116258
                     /locus_tag="LP433_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBL2004464.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            116284..116628
                     /locus_tag="LP433_000268"
     CDS             116284..116628
                     /locus_tag="LP433_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL2004465.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            116633..116914
                     /locus_tag="LP433_000269"
     CDS             116633..116914
                     /locus_tag="LP433_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004466.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            117017..117331
                     /locus_tag="LP433_000270"
     CDS             117017..117331
                     /locus_tag="LP433_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBL2004467.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            117309..119003
                     /locus_tag="LP433_000271"
     CDS             117309..119003
                     /locus_tag="LP433_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL2004468.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            119023..120201
                     /locus_tag="LP433_000272"
     CDS             119023..120201
                     /locus_tag="LP433_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL2004469.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            120164..120850
                     /locus_tag="LP433_000273"
     CDS             120164..120850
                     /locus_tag="LP433_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBL2004470.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            120850..122010
                     /locus_tag="LP433_000274"
     CDS             120850..122010
                     /locus_tag="LP433_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL2004471.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            122020..122895
                     /locus_tag="LP433_000275"
     CDS             122020..122895
                     /locus_tag="LP433_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004472.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            122892..123203
                     /locus_tag="LP433_000276"
     CDS             122892..123203
                     /locus_tag="LP433_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004473.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            123193..123546
                     /locus_tag="LP433_000277"
     CDS             123193..123546
                     /locus_tag="LP433_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL2004474.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            123536..123937
                     /locus_tag="LP433_000278"
     CDS             123536..123937
                     /locus_tag="LP433_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004475.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            123930..124334
                     /locus_tag="LP433_000279"
     CDS             123930..124334
                     /locus_tag="LP433_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004476.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            124346..124954
                     /locus_tag="LP433_000280"
     CDS             124346..124954
                     /locus_tag="LP433_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2004477.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            124974..125336
                     /locus_tag="LP433_000281"
     CDS             124974..125336
                     /locus_tag="LP433_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004478.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            125538..128969
                     /locus_tag="LP433_000282"
     CDS             125538..128969
                     /locus_tag="LP433_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL2004479.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            129020..129757
                     /locus_tag="LP433_000283"
     CDS             129020..129757
                     /locus_tag="LP433_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2004480.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            129767..132058
                     /locus_tag="LP433_000284"
     CDS             129767..132058
                     /locus_tag="LP433_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2004481.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            132082..134208
                     /locus_tag="LP433_000285"
     CDS             132082..134208
                     /locus_tag="LP433_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004482.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            134225..134374
                     /locus_tag="LP433_000286"
     CDS             134225..134374
                     /locus_tag="LP433_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004483.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            134371..134817
                     /locus_tag="LP433_000287"
     CDS             134371..134817
                     /locus_tag="LP433_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004484.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            134819..134956
                     /locus_tag="LP433_000288"
     CDS             134819..134956
                     /locus_tag="LP433_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL2004485.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            134994..135287
                     /locus_tag="LP433_000289"
     CDS             134994..135287
                     /locus_tag="LP433_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004486.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            135284..135508
                     /locus_tag="LP433_000290"
     CDS             135284..135508
                     /locus_tag="LP433_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL2004487.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            135505..136530
                     /locus_tag="LP433_000291"
     CDS             135505..136530
                     /locus_tag="LP433_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL2004488.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            136720..136793
                     /locus_tag="LP433_000292"
     tRNA            136720..136793
                     /locus_tag="LP433_000292"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:136754..136756,aa:Ile,seq:cat)
BASE COUNT        45723 a        22901 c        28759 g        40011 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat
    45121 aaagaaagaa gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa
    45181 cgttgattat atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt
    45241 tgactcctta tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga
    45301 tatatgtacg accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg
    45361 aaaattcagg aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag
    45421 atttttatac aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa
    45481 atattatcgg tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg
    45541 catttgcatg gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag
    45601 catggaatac ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag
    45661 aatgttaaaa acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga
    45721 gaaaacactc atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg
    45781 agtagtatgc gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt
    45841 atgcgtaccc agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat
    45901 gtagcagaag taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga
    45961 cagcttcagc ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc
    46021 atggccacga caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg
    46081 atcgagaaag ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt
    46141 gaaggtcaag cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg
    46201 gatagtgcaa aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa
    46261 ggtggcgttt tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa
    46321 gagattcccc gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg
    46381 atggatcatc ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg
    46441 acaaaggaat cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg
    46501 attgaatcga gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta
    46561 aaggatacag gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc
    46621 aattgataac cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag
    46681 ttgggccaaa ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa
    46741 tttaattatc tataattatt gatgttccgc tgattcttgt catagtagct cagctggata
    46801 gagcatccgc cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa
    46861 ccgttagaaa ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt
    46921 ttcaaaggca aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa
    46981 ataaaactca tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact
    47041 ctagttgcaa ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac
    47101 acgacaagta gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca
    47161 ttgtttaaga accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct
    47221 tatctttctt ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt
    47281 gcattatatg gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct
    47341 ctgttggcat tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag
    47401 gaaactttgt gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt
    47461 ttagaaaatt tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa
    47521 aaaaagaatt ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca
    47581 cagtagctgc tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg
    47641 cggccgcagg tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg
    47701 gtttttatca aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg
    47761 caacaaaggg aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg
    47821 cagcaggact tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg
    47881 ggtttacttc aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg
    47941 ttcactcgga aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc
    48001 cgataaacac agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc
    48061 caaaaaaatg ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag
    48121 ttatgctatt gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca
    48181 gtagtaatcg tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc
    48241 cagctattag cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg
    48301 gccgaatggc aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa
    48361 atctgttgct tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg
    48421 tggccatcaa atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac
    48481 tgctctccat gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag
    48541 gtgttttgat tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta
    48601 ctaataaata ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct
    48661 ttgatttaag tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca
    48721 aaagcgctgc tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag
    48781 aaacggaaaa gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt
    48841 cttcagaaaa actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct
    48901 ccatgcgagg cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag
    48961 aaaaagcaga gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa
    49021 aacaactttc tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg
    49081 cgttgacagc tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac
    49141 agacaagact gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa
    49201 aagtgaagct agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa
    49261 aatagctgct ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc
    49321 atccttttgt tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt
    49381 aaccgtatat tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa
    49441 ttttggctgg accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga
    49501 acgagtaggt gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg
    49561 atgagtcacg cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt
    49621 taagccagtt gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac
    49681 atgcgtatca atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag
    49741 aggtccttgc ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc
    49801 ttgtatcagt tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat
    49861 aaaagaaaca caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt
    49921 attgcttgaa tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt
    49981 ctggtaagct agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta
    50041 ataagcacag catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc
    50101 tttatagcat gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac
    50161 aagcaatcta tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag
    50221 ttatcttagt aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg
    50281 ttgaaggtac tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac
    50341 ctaaaaaaca ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg
    50401 acgcgatcaa cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt
    50461 taagcgaaat gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg
    50521 tccttatgga agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa
    50581 cgggattgcc tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg
    50641 ttatctttat accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat
    50701 tctattagaa aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat
    50761 ccaaattaaa acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct
    50821 acaattattt gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc
    50881 aaaacgtcta ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta
    50941 ccgtcaacgc ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac
    51001 tttatttgca aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca
    51061 agtgtctgtt tatccagtag ctcaagaagc ttaattgaat cttatgatta aagaggttgt
    51121 gacaagactt ttgtcacagc cttttttgtt tataaaaata aaagttgtag tggaggctac
    51181 gaagtttact ttgtcttttt acacttaata tttttttgcc aatttggaat caggatgttt
    51241 tgataactat cgttttcaat tgatggaagc tatattgttt gctatcagtg aaataattat
    51301 atggtaaaca gtgttctttt tcttgtttcc attataaaaa tcgtatcggg atttttcgtt
    51361 cttttaaatt gaacatttct atctatccgc gtgttatcaa caaaacaaaa tcaggtaaat
    51421 agttgacgaa acagaaataa atacatagta ttatgttttg aagcctaagt acaatagtct
    51481 atagaaaagg agcgatacca ttggcaaaac gcattgaccg aatttatatg tatgtcaaag
    51541 aaaaaaccgc tcatttaaca aaggcagaat atgatcaagg agtaacaaca caggaaattg
    51601 ctgaagtgtt agggattcag cgaacaaata gcagtaaaga tctgaatcag ctagtgcgcg
    51661 aaggaaaact gataaagaca gacggacgac cagtacgtta catatatcaa acactcgtta
    51721 cgcacgtaaa gccagttaca aaacatgtag tcagttacaa agaaacgccg gtctctgaag
    51781 aaaaaaatac actccaaata gatactaagg atatctttgc aaaaatcatt ggagctaacg
    51841 gcagcatgaa aaattcagtg gaacaggcaa aagctgcgat tttgtatccg ccaagaggat
    51901 taaattgttt gattacagga cctaccggat caggaaagac ttattttgca cacgcgatgt
    51961 atcattttgc aaaagcgcat catgtaatag atgaggaaac ggaactgatt gttttcaatt
    52021 gtgctgatta tgccaataac cctgagcttt tgatgagtca tttatttggg tacgcaaaag
    52081 gtgcttttac aggcgcagat gaagaaaaaa tggggattat cgatcaagcg gatggcggta
    52141 tgctgttttt ggatgagatt caccggttgc cgcctgaagg tcaagaaatg atcttttact
    52201 ttatggatca tggaacttac agtcgtcttg gggaaacaac gaaatcccat gaagcaaatg
    52261 tacggatcgt aggtgcgacc acagaagacc caggttcttc tctattagaa acttttgttc
    52321 ggcgtatccc aatcaatatc aaacttccgg cttttgaaaa acgtcctgca aatgagaaag
    52381 tcgatttagt aaaaatcatg attgcccacg aagcaaaccg cacgcagcga aagatttctt
    52441 tgacagaaga tgtagcaaaa gcattgatcg gcagtgtgac ctatggaaat ataggacaat
    52501 tgaagtcaaa tatccagtta gtatgtgcac gaggatttct aaatcatatg caatcacccg
    52561 aaatctcgat cacaatcgat gatttgacag aagggattcg tagcggattg attcaattag
    52621 caagcaaccg cagtgcaatg gcagagcttt ctaaaatatt ggagccaaag ataactgtag
    52681 caccaaatga tacgatcatg aaaatccaat cggactccta tgagttacct tataatctat
    52741 atgatatcat cggagataaa gcagctttac tgaagtcgga tggtttggat caagaagcaa
    52801 tcaatcattt catttctaca gatatcaaca tccatctgaa gtctttctat aaagaccatg
    52861 gtttttcttt taatgcagac agcaaattag cagaatttgt agatccgaaa atcatagaag
    52921 tgaccaatca gatttatgta atggtcaaaa gatctttacc atatgagttt cagcaaaact
    52981 ttatttatgc tatgagcttg catatcagtt cttttttgaa aaaaatcaac ttaggagaag
    53041 aacggcatac gaatgataac atccgtgaga tggcttttga ttttccagat gaatatgctg
    53101 ttgcgaaaga agtgcgtagt tatatcgaaa cgtattttca agtggagatt ccagaaagtg
    53161 aagactatta cttgaccgtt ctactcgtct cgttacgggc aaatcaagca agcggcagaa
    53221 tcggtgtagt cgttgcagct cacggaaaca gcacagcaag cagtatggtc caagttgtcc
    53281 aacagttgtt agatgcagag aacgtacgag cagtagacat gcctttggat atggatccga
    53341 aaacagcatt ggaccgaatt gaacgcaatg tacaagaagt agatgaagga agcggggtca
    53401 tactcttagt agatatgggg tcccttgcgt cgtttaattc gcaaattcaa agagacactg
    53461 gaattccagt acgtactgtt gatatggtaa caacttctct agttttggaa actgtacgaa
    53521 aggtctcagt attagggaca gatctagata tgttgcatga atcattgaaa aattttcgag
    53581 gttacgcaga aatatcttct gtagaatctg ttcaggaagc aaaacctatt cataagaaaa
    53641 aagctgtttt ggctatctgc gcatctggcg aaggtacagc acaaagaatc aaagaattga
    53701 tcgaacgagc ggtaaacaag cgtcaagaaa cagaattaga agttctagct ttgtcgattg
    53761 tggaagtgaa agaagaactg ccagttatcc aaaaagaata tcagatcata gctactactg
    53821 ggattactga tttgaatatc caagccccat ttattccttt agaacgtttt attgatcaaa
    53881 atatcgaagt cattttggat cagttgctga tggaatcaga attggaggaa actgaattca
    53941 tctccctaga tgaagagtca gctaaaaata cgtgtgttga gtttatctct gataacttca
    54001 tctttattaa tggtagtaag ttaatcgatc caatgtggca attttctaca caaatctctc
    54061 agacgacggg aatcggcgat gaagaatatg gattcaaaat caacctagtg atgcacacag
    54121 caggaatgat cgaacgtatt attcggaatg aaccattgac tgtggaagaa aacgaattga
    54181 caaatacaac gaatgatcct ctttatagcc aattggcagc ctcagttgtt ctgttggaag
    54241 atcagataaa agtaaaagtg ccgatagaag aaatgtatta tctgctacgt ctagtccata
    54301 atcagttaga taaaaaagaa tacactgtgc catgaataca caaaaacgat acacttttat
    54361 agtgtatcgt ttttgtgtat tggttaagaa tcctttaaat tcaattagtg tatcgtaaaa
    54421 aagttggcac gctttttgct tatagtagtg tgtgctagga ggtggttgtt cacacagaaa
    54481 tgataggggt ttctgtgaag tagtgaggaa gaaggagttt tgcagatgga tattcgattg
    54541 gcacgtatag atgatcgttt aatccacggg caagtcgcaa cagtttggtc gaagcaaaca
    54601 ggtgttgaac gtatcattgt gatcagcgat gtagtcgctc aagataaatt gagaaagttt
    54661 ctactaaaag aagctgcacc gccggggatc acagcaaatg taataaccgt gcagaaaatg
    54721 attcaaatct atcatagtgg attattatca cgagcaaaag tgatgctttt attcaccaat
    54781 ccccaagatg ttgaagcggt tgtccgctgc ggtgtacagt tgaagtcgtt gaatatcggc
    54841 ggtatgagtt ttactgaagg caaatcaatg attaccaatt ttgtttcagt aaatcaacaa
    54901 gatattgatt cctttcgtta cttgaacagt caagaagtgg agttagagat tcgaaaagta
    54961 cctgctgaca ggaaaatcct tttgatggaa ctactagcga aaatcaaaaa ggtgtagcaa
    55021 gaatggttgt tggaaaaggt caaataattc tgttgtaatg gttagcaatt attaatattt
    55081 ttgaatttgt tacaacaaaa gtaaatagga ggtataaata tggtagggat tatcctagca
    55141 agtcatggac aatttgctga aggaatctta caatccggtt caatgatctt tggcgaacaa
    55201 gaaaacgtca aagccgtgat tttgaaacca agtgaaggtc cagatgactt gagagccaaa
    55261 ttggaagaag cggttgcttc ttttgataat caagacgaag tgttattctt agttgattta
    55321 tggggcggaa caccgttcaa tcaatcaaac acattattcg aagagcacaa agataaatgg
    55381 gcaatcgtca gcggtttgaa tttaccaatg ttgattgaag cctacgcatc acgcttttca
    55441 atggaatctg ctcatgaaat tgcagcacac atcattgaaa cagcaaaaga cggtgtaaaa
    55501 gtaaaaccgg aagaattaga accggcagaa gcaccgaaag cagcagttga agacgcacaa
    55561 cctaaaggag cacttccaga aggaactgtg gtcggagacg gaaaaatcaa atatgtatta
    55621 gcacgtgttg actcacgtct gttacatgga caagttgcga cagcttggac aaaagcagtg
    55681 caaccaaacc gtattatcgt tgtttcagat gcagtatcaa aggatgatct gcgtaagaga
    55741 ctaatcgaac aagctgctcc tccaggtgta aaagcaaatg ttattcctat tagcaaaatg
    55801 atcgaagtag caaaagaccc tcgttttgga aataccaaag cattgctttt atttgaaaat
    55861 cctgaagacg tattgacagc tgttgaaggt ggcgtagaca tcaaagaatt aaatgttggg
    55921 tcaatggcgc attcggtcgg taaagtcgtt gtaagtaaag tattgtctat gggacaagaa
    55981 gacgttgaag cgtttgagaa gcttgaacaa aaaggtgtga aattcgatgt acgtaaagta
    56041 cctaatgatt cacgcgataa catggatgat attttgaaaa aagcaaaagc tgaattagca
    56101 aaagcgtaat aaataatatt aaaatttata ggaggcttat catgtctatt atttcaataa
    56161 ttttagtcgt attagttgcc tttctagctg gtatggaagg tattcttgat gaatttcaat
    56221 ttcatcaacc actagtggca tgtacattga tcggtttagt taccggtaac ctcgaagctg
    56281 gtatcgtact tggcggtacg cttcagatga tcgctttagg ttgggcaaat atcggtgccg
    56341 ctgtagcacc agatgctgca ttagcatcag tagcatcagc aattatttta gttttaggtg
    56401 gacaaggtgt taaaggtgtt ccttctgcga tcgcgattgc cgttcctttg gctgttgcag
    56461 ggttgttctt aacaatgatc gtacgtacaa tcgctgttcc aatcgttcat ttgatggatg
    56521 cggctgctga agaaggaaac atccgtaagg ttgaaatgtg gcacatcatt gctgtatgtt
    56581 tacaaggggt tcgtatcgcg gtcccagcag cagcgttgct atttatccca gcacaaactg
    56641 tgcaatcatt ccttgaatca atgccagcat ggttaacaga tggtatggct atcggtgggg
    56701 gaatggtcgt agctgtaggt tacgctttgg taatcaacat gatggctaca aaagaagtat
    56761 ggccattctt cgttattggt ttcgttgtag ctgcaatttc tcaattaaca ttgattgctc
    56821 taggtgcttt aggtgttgca ttagctctta tttacttgaa cctttctaaa atgggtggtt
    56881 catcaaataa tggaggcgga agcaactctg gtgacccttt aggcgacatt ttgaatgact
    56941 attaatcttg aaggaggaaa ataaaatggc agaagaaaaa atcaaattat caaaaaaaga
    57001 tcgtttagct gttgcgtggc gctctacctt cattcaaggt tcatggaact acgaacgtat
    57061 gcaaaacggt ggctgggcat tttctatgat tccagcaatc aaaaaattat acaaaacaaa
    57121 agaagaacgt tctgcagcat taaaacgtca cttggaattc tttaatacac acccatacat
    57181 tgcttctcca attttagggg ttacattggc tctggaagaa gaacgtgcga atggcgcgcc
    57241 tgttgatgat gtagcgattc aaggggttaa agtaggtatg atgggtcctt tagctggtgt
    57301 tggtgaccca gtgttctggt ttacagtacg tccaatgcta ggtgcactag gtgcttcatt
    57361 agctatggga ggaaatatcc ttggaccaat catcttcttc ttaggttgga acattattcg
    57421 ttgggcattc atgtggtata cacaagaatt tggctacaaa gctggttcta aaattactga
    57481 tgacctttct ggcggattgt tacaagacgt aacaaaaggt gcttcaattt tagggatgtt
    57541 cgtattagct gcccttgtag aaagatgggt atcaatcaaa ttcttaccag ttgtatcaac
    57601 tgtaaaatta gataaaggtg cttacatcga atgggataaa ttgccttcag gtggtgaagg
    57661 aatcaagagt gcatttgaac aagttaataa tggcttagcc ctttctcctg aaaaggtaac
    57721 aacattacaa gacaacttag accaattgat tcctggttta gctgcattag gattaacatt
    57781 gttatgtatg tggttgctta agaaaaaggt ttctccaatc gttatcatcc ttggtttatt
    57841 cgtagtcggt gttgttggac acgtcatcgg acttttataa tccataaaaa tatagctcgg
    57901 gcgttgtccc gagctttttt tatatagtat actgttcata aacaaatatc tggagggaga
    57961 aaatggttca atcaatcaat acaaaagtag acttggtaat tgatgctact tcgtttacgg
    58021 gtctgacaga ttacgggcaa atcatgatag gtgataatgg ttttgagttt taccatgcgc
    58081 gagatagacg caaatatatc caaattccat gggaagaagt ggattatgta ctagcatcag
    58141 tcatgctaaa gggaaaatgg attcctcgat atgccattca aacgaaaaaa aatggtacat
    58201 acacattttc ttccaaagaa cctaaaaaag tgcttcgtgc gatcagagaa tatgtagatg
    58261 aagatagaat ggtacaatca ttgagtttct ttgatgtagt gaaacgtggt attcgtagta
    58321 tgtttaaacg caagtaaaaa ataaagaaaa cttctaagag gaggttttct ttattttttt
    58381 actttgcaga agaaaatatg aaatagcaaa accaattatt tgtccccttt aaatcccata
    58441 tgctaaaatt gattagcaaa gaaggaggtt atattatgag ttggttatgg acattgattg
    58501 ttggagccgt gatcggagca attgcaggtg cgatcaccag taaaggaaat tcgatgggct
    58561 gtgtaacgaa tatcattgct ggactagtcg gttcaagtat tggacaagcg attttcggcg
    58621 aatggggacc aaaagctgca ggtatggcac ttattccatc tattttaggc gcagtgattt
    58681 tggtagcagt tgtctcattt ttctttggaa aacgatcata agtttttaca aaatagtaaa
    58741 ctaaaaggag ttgcagcgag actgtgactc ctttttggct ttatttattt aaaataaaaa
    58801 gaagttttcc ggaaattttt atttaactgt cgtgtacgaa gaaaagtttg ctataatgga
    58861 aaaaagcgtg caaagaaaga gggagtttca ttatgatgct acgtgtagaa aaattgcgca
    58921 aaaaaatgca agaagaaaat ttggattcat ttttggttac cagtccgtac aatcttcgtt
    58981 acttaacgaa ctttacaggt acgacaggat tagctgttat tactttggaa aaagcatttt
    59041 ttattactga ttttcgttat accgagcagg cggcagcgca ggctcaaggg tttgaaatta
    59101 ttaaaaatgt cggacctatt tttgatgagg tagcaaactt agtacgcaaa gaagaactgc
    59161 actcattagc ttttgaggaa acaacagtct catttttaga atattcggtt ttagaagaaa
    59221 tcatcgatgc ggaattagta cctgtttcac agatgatcga agaactcaga gaagtgaaag
    59281 atgaagaaga aatcgctatt atcgaaaaag catgtcatat tgcggatatg gcatatgatc
    59341 acatcctgaa aatgatccaa ccgggcatga ctgagattga agtcgcaaat caactagact
    59401 tttatatgcg ttctcttggc gcttcaggtg tttcttttga tacgatcgtt gctagcggat
    59461 tgcgttcggc tatgccgcat ggtgtagcaa gcaaaaaaat catcgaacaa ggtgacttga
    59521 tcacattgga ctttggttgc tattacgaag ggtacgtttc cgatatgaca cgtacattcg
    59581 ctattggtga tcctggggaa aaattaaaag aaatttatca aatagtctta gatgctcaat
    59641 tagcagttat tgatgctgca aaaccaggaa tgactggtgt ccaattagat gcagttgcta
    59701 gagattatat ttcaaaacat ggttacgggg aagcatttgg acattctaca ggacatggga
    59761 tcggtttaga gatccacgaa ggaccaaacg tttcttctcg tgcagaaaag caatttgtac
    59821 caggaaatgt gatcactgat gaaccaggga tctacttacc aggaatcggt ggagtacgta
    59881 ttgaggatga cttgttgatc acagaagatg gaaatcgtgt gttgactcgt tcaccaaaag
    59941 aattgatcat cttatagttt catcaataga agaagtaagc gtaaaaatca gtgttcacag
    60001 actttgttat agaaaatcac tcgatttaat gatacactat agaagaactt ttaagctgta
    60061 agagataata aagttgggtg ttttctccaa ttcatagcag tttgcagctg atcggcggca
    60121 gttttcttac cacgtgatca ctatgccgca tcatagagaa ttcggatgta tctcgtgctt
    60181 aggcaaaggg aggaataaat aaatggcaga tgaaaaaaat ttgattttaa acgcaaacca
    60241 agatttagga gagatcgtga tcgctcctga agtcatcgaa gtaattatcg ggattgcagc
    60301 ttctaaagta gaaggcgtat acggaatgcg cggaactttt gccagcaatg tcactgaatt
    60361 attaggacgt gcagctcacg gaaaaggtgt ttacttagca aacgaggaag atggcttgaa
    60421 agtagatctt tactgttatc tagaatatgg tgtttcagtt cctaaagtag caatggaaat
    60481 gcaggaacgg gtcagccagc aagtcctttt catgacggat atcgatttat ctgaagtcaa
    60541 tatccatgta gtagctgttg ttcctgaaaa attagaacaa ccaacaatcg aagaactttt
    60601 tgaagacgaa gaggaagaga atgaataaag aattatcaag acacgagatt cgggaaatgg
    60661 cattgcaggc tttatttcca ttagacttca atgcagacct aacaaaagaa gatgcgattt
    60721 tcaacgcaat cgaattagac caccgcgaca tgatcaacga agatgaatca gagtttgttc
    60781 ctgtttatct tgatacgcta gttggcggtg tctgtgcaaa aaaagatgaa ttggataaag
    60841 tgattgaaaa acatttaaaa aacaattggc acatcaatcg gatctcaaaa atggatttgg
    60901 tgatcttgcg tatcgcgatt tttgaaatga cttatgtgac agatgtacca gcggctgttg
    60961 ctttaaatga agcaatcgag ttggcaaaaa catttagtga tgaccgttca cgtaaattcg
    61021 tcaacggtgt tttatccaat gtattgaaag aattagaagc tggggcgtaa gtcctagctt
    61081 ttttctatga atcatcataa acctgttata aatcgggaaa attctatggt agaatgaaaa
    61141 cacaaaaaat atctgggagt ggttagatgg cagaattgat taacggaaaa gaattagctg
    61201 aaaaaatgca ggcagagatt gctgaaaaaa tccaaaaatt gaaagataat ggtatccatc
    61261 ccggattagt cgttttattg gtaggggaaa atccagccag ccaaatctat gtaagaaata
    61321 aagaacgtgt agcaaaagaa atcggaatcc attcattggt agagcgttat cctgagacga
    61381 tttctgaaga cgaactactt gcagaaattg aaaaatacaa tcaagatcct agttttcatg
    61441 gtatattggt ccaattacca ttgccaaagc atatagatga agaaaagatc ctgttagcta
    61501 tccgccctga aaaagacgta gacggttttc atccgatgaa tttaggcaga ctccttgcgg
    61561 gtaaaccgga caagattcct tgtactccat acggcatcat gaaaatgttt gaagcttatt
    61621 ctatcgatcc ggcgggtaaa cgagcagtag ttatcggacg aagcaatatc gtcggtaaac
    61681 cgatggctca gctactcttg atggcagatg caactgttac tgttgctcat tctaaaaccg
    61741 aaaatctggc tgaactggca caagaagcag atattttagt cgtagcaata ggacgtggac
    61801 attttgtcac aaaagaattc gtaaaaccag gtgctgtagt gatagatgta gggatgaatc
    61861 gtgatgctaa cggtaagctg atcggtgatg tgaaatttga tgaagtggag cctattgcag
    61921 gctggatcac tcctgtgcca aagggtgtag ggccaatgac tatcacgatg ctgatgtatc
    61981 aaaccgtaaa atctgccgaa gcttttggag caggtgaata gatggcacaa gaatatttaa
    62041 ctgtcactac attaacgaag tatttgaaaa gaaaatttga tgccgatcct tatttagaac
    62101 gcgtatattt aacaggcgaa atatcgaatt tccgtttacg tgccaatgcc catcaatatt
    62161 tcagcttaaa agatgaccat gcaaaaatat ctgctattat gttcaaagga gcattccaaa
    62221 aattacgatt ccagccaaaa gaaggaatga aagtccttgt cgttgggcgt atttcattat
    62281 atgaagcggg aggttcttat caaatctatg tagagcacat ggagcctgat ggaataggtg
    62341 ctttatatca agaattggaa gaacgaaaag aaaagctgat gaaggaaggc ctttttcaag
    62401 ggcctaaaaa aatgctgcca cgtttcccaa agcgaatcgc ggtccttacc agtccaagcg
    62461 gagcggttat ccgcgatatc atcacgacgg tgaaaagaag atatccaatt gtccaattgg
    62521 ttttgttccc aacagttgta caaggaaacc aagcagcgga caatgttgtc aggaatatcc
    62581 agagagtaga agagatgggc aatttcgata caatgatcat cggtcgtggg ggtggttcga
    62641 ttgaggattt atggccgttt aatgaagagc gggttgctcg ggcgatttat caagctaata
    62701 cgccggtgat ttcatctgta ggacatgaaa cagataccac gatcgctgat ttagtagcag
    62761 atgttcgggc tgccactcca acagcagctg cagaattagc tgttcctgtt ttgtcagaag
    62821 agttgatgcg cattcaagaa cggcaagcta gattgcagca ggcgtttgta cgccagatcc
    62881 agcgcaaaca agaacggttc gagcgtgctc gacgttccta tgtatttcgg cagcctgaaa
    62941 gattgtatga aggtcagacc atcaaattag accagttgaa acagcgatta tatcaagcta
    63001 cacagcaaat ttatcatgcg aaagaaaaac aaacgatcgc attaagccac caattggaac
    63061 aagtggctcc gctttatcga gttaaagcag ctcgccaaga aactgcttat ctagaaaaac
    63121 gcttagaaga gaaaatccaa caatatatga aacaacagca gcagcgtttt gctcaagctg
    63181 ttcaatctct tgatttgttg agtccattga aaatcatggg aagaggctac agctatacga
    63241 cgttaaatga tcaagtagta aaaagtgtca ccgagattca tcaaggggat ttgctgacga
    63301 tccattatca agatggaatc gttaaaggac aagtacaaga gatagacaaa ggagaataaa
    63361 aatatggaaa atccaacttt tgaagagtca ctgcaagaat tagaaaaaat tgtcatgcag
    63421 ttagaacaag gagacgttcc attagaatca gctctagatt cgtttaaacg aggaatggaa
    63481 ttaagcaaac attgccaaga tacattagct aaagcagaag agaccttgac gaaaatgatg
    63541 acagaatcaa atgaagaagt tgattttgac ggaaacgagg aaagctgaga tgagattaac
    63601 tgacttttca gctattcatc tacctgctgt agaaaaagaa atcttgtctt ttttagatga
    63661 gcatacaacg gatagaggac tctatgatgc gatgagttat tcagtgaaag caggcgggaa
    63721 aagaatacgt cccttattac ttttaacggc cgttgcttcc tttgatgagc ctattgatgt
    63781 tcccgtctat caagtagcag ctgctttaga aatggtgcat acgtattcct tgatccacga
    63841 tgatttgcct gcgatggaca atgatgatct tcgtagagga aaacctacca atcataaagt
    63901 attcggcgaa gcattagcta tattggccgg agatggtttg cttacaggag cattccagct
    63961 aatcagtatg gcacacttag gtaattctcc taagcttctg ctgcttcagc aattagctgt
    64021 ttgtgcggga tcacaaggta tggttgctgg gcaagctgca gatatcgagg gcgaatcgaa
    64081 aaagctttct ttagaagaat tagcatttat tcatgaaaga aagacagggc atttgattcg
    64141 ttatgccttg ctggctggtg gcatattagc gaagcaacct gaagaaatct tattgctact
    64201 tcaacgatta gccgaacatt taggtttagc ttttcagata agagatgatc tactcgatgt
    64261 gattggtaca acgaaaacat tagggaaaac agctggtaaa gatgaacgta tggaaaaaaa
    64321 tacttacccg cgtttattag gcctagaaaa gacacgtgag gcgttggaga ttgagctgtt
    64381 atccgccaac aagatcatag acaaattaga agaggacgtt ttttcttttg atggcgggct
    64441 gatgcgccag atgatcaagc aatttgatgt ggagaaatga gggaaagaat ggaaaaagaa
    64501 cgcgtagatg tattagcggt caaacaagga ttatttgaaa caagagaaca agccaaacgt
    64561 tcagtgatgg ctggtttgat ttacaacgaa aaaaacgagc ggtttgataa accgggagaa
    64621 aaaattccag tgagtagtga attaagagtc aaaggtaaaa aacttcctta tgtttctcga
    64681 gggggattaa aattagaaaa agcactcaaa gcatttgatc tatctgttga aggaaaaaca
    64741 ttgttagata ttggtgcatc cactggcgga tttactgatg cagctttgca aaatggcgca
    64801 aaaatgagtt atgctttaga cgttggctac aatcagctag cttggaaaat aagacaagat
    64861 cctagagtcg tcgtaatgga aagagtgaat tttcgttatg caaaacccga agactttacc
    64921 ttaggaattc cagaagttgc tgttatcgat gtttctttta tttcactaaa actgatgctg
    64981 cctccattac atgctatttt aaaagaagag ggagaagtga ttgctttaat caaaccccaa
    65041 ttcgaagcag gcagagaagc tgtagggaaa aacggaattg ttcgtgaccc tcagacccat
    65101 caaaaagttt tagaagacat tttgtcattt gcggcacaag gtggatatga tgtgctggaa
    65161 ttaagttatt ctccgatcac ggggggagaa ggaaatatcg agttcttggc tcacttgagg
    65221 aaagtacccg aaagcggaac aatcaattca gctattaata tggcagaagt ggtttcaaat
    65281 gcacacgaac agtttgacca taaataaatt gtaactgtga aaatcaagtg agaagtatgc
    65341 ggattcttct ttattatacc aaggaaataa gctatcattg attaagaaga atatgctaag
    65401 gagcgaagac gtaatgagaa aaaaagatcg gcatcgtttg attactcgat tgttgagtga
    65461 gcaagatatc cgaaagcagg aagaatttgt tgaaatcctg aaaagcaaag gaatatctgt
    65521 tactcaagct acgatttcca gagatataaa ggaactgaaa ctgatcaagg taccggcttc
    65581 agatggcggc taccgttata gcataccagc tgaaacaaac gaagatgtaa atactaaatt
    65641 ggaaaaacta ttaaaagacg ctttcgtggc agttgaccaa atggaaaaat ttgttatttt
    65701 gaaaacattg ccgggaaatg cttcggcagc agcaaatttg attgataaac gttacaagaa
    65761 agaattattt tcgattatca atgatgacga taatgttttg atgattacac gaactgaaga
    65821 ccaggcagtt ttattgaaga aagacttcct gcattacctt taagttgagg agcgaatgtg
    65881 atgctacaag aaatcagtat tactaacttt gcgattattc cggaattgcg gctttctttt
    65941 cacgaaggaa tgaccgcgct gaccggagag actggtgcgg gtaaatccat tattatcgat
    66001 gctttaggtc tgttagcagg aggaagaggt tcaagcgatt atatacgtca aggagcagaa
    66061 aaatgtgtgc ttgaagggtt gtttgaacta ccaaaacaag aaggattctc tgaactgatg
    66121 gttgaattag ggatcgaaac agatgaggac aatctgattg ttcgacggga tatgtcctta
    66181 actggaaaaa atgtttgtcg agtgaatggt catattatca cattagctaa tctgagaaga
    66241 atcggcagtt atttagtaga tatccaagga caaaacgaac atcaggaact gctccagcct
    66301 gaatcacatc ttgctttatt ggatcgtttt ggagatgtag ctttccaaca gaagaaaaag
    66361 agttatcagc aagaatatat ctcttatcgt gagctggaaa aaagggtacg aaaagtgcag
    66421 caaaatgaaa aatcctatgt tcagagaata gatatgctcc atttccagca agaagaaata
    66481 gctgctgctg atttgcaagt cggagaagaa gagaaattaa aagaagaaag agaaaaactt
    66541 agcaattatc aaaaaattgc tgatggatta gctgcaggtt acggagcact gacgaataat
    66601 gaacaaaaca gtgtagatgg tgttggcttg gccgtttcag aactgcaagg gatcgcccat
    66661 ctagatgtgg agtatgaagc aatttatgaa aatatccaaa gtgcttacta tttgctgcaa
    66721 gatgcaatcg gcgatatgag tcgtcagatt gatttattgg agttagatga gagtcgttta
    66781 gaagaagtta cgcaacgttt agaattaatc cgacagttga aacgtaaata cggcgaatcc
    66841 attgagtcaa tattggctta ctatgacgaa atcaccgaag agctagcttc ttctgatttt
    66901 tcagaaggtc aattggacaa aatgaaagag gaactagagc aaaaagagct tctacttcag
    66961 caacaagccg cagatcttca tgaagcgcgt aaaaaaatcg caaaagaatt ggaaaaatcc
    67021 attctgcatg aattgaaaag tctgtatatg gaaaacactg agtttgaggt acgtttctta
    67081 aaagaagaaa atagacaatt gaatcatgat ggatttgacc aaatcgaatt ttacattacg
    67141 accaatccag gagagccact gaagcctttg gtgaaagtcg cttctggtgg cgaactgtct
    67201 cggatgttgc ttgctttgaa aactattttt tcttctgagc aaggtgtgac aagtattatt
    67261 tttgatgaag tggatacagg tgtgagcgga agagttgcac aggccatcgc agataaaatt
    67321 tctcaaatat cgaaatactc tcaagttttg tgcatcactc atctgcctca agttgctgca
    67381 gtcgccgact atcaatatta tattgtgaaa gcagtgattg atggacgtac gcaaacttct
    67441 gtttcagagt tgaaaacaaa agaaagagaa gaagaaattg cacgtatgct ggctggaagt
    67501 gagattacaa aactcacact cgaacatgca aaagaactat tgaaactcgc aaaaaggacc
    67561 tgagccacct cgcagtggtt caggtccttt tcagcagctg atagctatat tttattttta
    67621 catgacactc attacagcag tcaatacaac agatccaatc gttaaaatca gcattgtcca
    67681 aatgacaaat tttgttactt tagcaaaagt acttgtttgt tttttttcac gcattgtttt
    67741 caacctcgtc attaattagt tgattcaagt gtacaatctt ttttccattt ccacaagagg
    67801 gcttttttat aaaaacttcc ctttttttaa ataataggta gttacgatac aaataaataa
    67861 tgttaataga actagccata taaaggcatc atccctttca gcaataggta acttaatgtt
    67921 cattccatag atactgccga cgattgtcgg tatagttaaa ataatcgtta aagaagttaa
    67981 aattttcata atattattca gattattcga tacgattgct gaaaaagtct gattcatttg
    68041 ttctactagt tttaattgaa tgcgagaagt agtcattgcc tgctctgttt ccaccaatac
    68101 atcacgtaaa tgatttttca aagcatgatt ttcttggaaa agtttatttt gcgctagttc
    68161 tttcaatgca tctaaattag cagaagtcgc ttctctgaaa taaacgaggc ttttttggat
    68221 atccatgatt tgataaagtt gtttgttttc agtggatact tgaagtttgg cttccaaagt
    68281 atcgcattga gattgaagcg tagctaaata actgttgtaa gagagtgtga cctgccaaat
    68341 gaattgaaag aagatattga gattaggcga aatatcactt tttggaaagg tctggctaaa
    68401 gactttcttt aaaaacagtg gttcatgatt cgtaattgtg ataagcttct ttttgggcgt
    68461 caaaataata gagagcgggt atgtatccac ttgaaaataa ccgctaggac ttgttttagc
    68521 aaaaggatat tgtaacaata ataacgctgg ctttgtcaac tttgattgat tgaattcttc
    68581 tgtacgggaa ttttctgcat cgtccaatat ggaagtgatg taatctgacg gaatttcaaa
    68641 ttgatgtgtc agctgatgaa tctcttcttg attaggacgt tctacacaat accagatcgt
    68701 ttggtcagtt tcctttccgg tattacgcag tttctcatta tctaatgtaa aatatttgat
    68761 catgattttc ctcctgttgc ctgtttcttt tattataacg gatagggaat tggaatacat
    68821 ggaatgtgtt tgtaagatat agaatataac tgcataaatt taaataaaat gaaacagttg
    68881 tgtaaagtat atacagtata cttgaagcaa cgataaaaaa ggagtttacg ttcatgggca
    68941 cattcacacc acttatcttg ttttggtata tttacccggt aatcgttttg tttggttgcc
    69001 aatttcttgt aaaattattt tcgttaaatc gtcgttttaa aataaaagcc cctgatttgg
    69061 cgattccttt tttgtggggc ggtatgcatg cattgtctag aaatacaggg acaatttcta
    69121 tcttaccgtt tttctttatt tctgttttgc taatgggaat ttgtattgct gttttccaag
    69181 catattatta tgaagaaatt atttatccgc gttatttcaa gatgacttgg cgtttggttt
    69241 ttctgttgac aatcgtcttg tacgctgtct tgatcattgt gaacatactt tcttacctat
    69301 gaaaaaaata gaaaagctgt aaaaagtctt ttaaaaggct ttttgcagct tgatttttaa
    69361 aaaaatgttt atgaataaaa aaagttgttc ccggatttcc cagaaaaggt ggtagaaagt
    69421 gggggattgt ggtagactaa ttttagttag tggaggaatg gggggctttc aatgttgatg
    69481 ggtgaattcc aacataatat tgatgcaaaa ggacgtttaa tcgtgccctc aaaacttcgt
    69541 gaagaacttg gcgaaaagtt tgttctgaca cgcggattgg atggctgtct tttcggctat
    69601 ccgatgagcg aatgggaaaa tctggaagct aaactgaacg aaatgccgtt ggctaaaaaa
    69661 gacgcacgta cttttgtgcg attcttctat tcggctgcca ctgaatgcga acttgataaa
    69721 caaggacgaa tcaatatacc cagcacgtta agaaattatg cagctttgac aaaaggttgc
    69781 gtagtcatcg gtgtatctaa ccgaattgaa atttgggatg agacacgatg gcaagatttt
    69841 tctgcagcag cagaagagaa ctttgacgaa attgctgaaa gtatgattga tttcggacta
    69901 taagaatagg aagaggctga ctaatgactg aaacatttca acactataca gtcatgttga
    69961 aagaaacggt agatggattg aacatcaaac cggatggcgt ttatgtagac tgtacactcg
    70021 gcggtgccgg acatagtgaa tatttattaa gccaactaag ttctaaaggg catctgtatg
    70081 cgtttgacca agatcaaaaa gcaatcgatc acgccaagct gcgtttagct tcttatgtcg
    70141 aacaaggtat ggtcacattt atcaaagcga acttcagaga attagaagaa cgcttgagtg
    70201 agcatgtaga taaggtagac ggcattttgt atgatctagg ggtttcctct cctcagctag
    70261 atgaagcaga acgtggattt agttatcatc aagatgcacc gttggatatg cgcatggatc
    70321 agtcagctcc tttatccgct tatcacgtaa ttaatgaata ttcctaccat gaattagtaa
    70381 agattttctt ccgctatggc gaggagaaat tttccaaaca aattgctcgt gaaatcgaac
    70441 gagtacgaaa aacaaaacca atccaaacaa ctggtgagct tgtcgaaatc attaaacaag
    70501 tcatcccagc tcccgcaaga agaaaaggcg ggcatcctgc aaaaagaatt tttcaagctg
    70561 tgcggattgc agtaaatgac gaactcggtg ccgaagaggc ctctttagaa caggcaatcc
    70621 ggttattgaa agtcaatgga agaatcagcg taatcacatt ccattcattg gaagacagaa
    70681 ttgtcaaaag tatgtttaaa gaatatagta cggtacaaga tctaccaccg ggacttcctg
    70741 tcatacctga cgaattccaa ccagaactga aagtcattac tcgtaaacca atccttcctt
    70801 cagaggaaga gctaacagaa aacaatcgat cacgcagtgc aaagttacgt attgcagaaa
    70861 aaataagaat gaaagaggag tagaatgatg gcagaattaa agaaaatgca agattacgaa
    70921 tatgatttac ctgaattggt ggatcagccg gaacaacaaa tgcctgattc ttcttcgaat
    70981 caagaaatca ttcttccaca atcaccggca aaacgattaa agcagatttc tgctttggaa
    71041 aaaattgctg tggcaagcgt ggcgattgct attgttgctt tatgtgtttt aacagttatg
    71101 ctgcgcacaa atatcagcgg agctgaaaaa gaaatcacgt caatacaaac agaaatcaat
    71161 gataaaaagc aagaaaaaac gagtttagaa caagaaaaaa acgaactttc tcgtactgaa
    71221 cggattaaac aaatcgcaga agaaaaagga ttgtctatta atgacgacaa tttaaggaaa
    71281 gtgaagtaaa tgagtcttaa aaataaaatt cggcggttta tggaaaagaa aaatctaaat
    71341 ccgatgaaca atcgcaaaaa agtaggtatc attttatttg ctacgagtat tggaatgttc
    71401 tttttatttg ccgtccgttt ctcgtatatc gttattggag gtcatgttgc tggtacctca
    71461 ttagctgaaa aaacaaaaca gttgtaccaa ggaagtgaag tagtaaaagc aaaaagagga
    71521 acgatttatg atcgtaacgg tgtggcgctc gcagaagatg cctcctctta ttcaattaaa
    71581 gcgatactct caaaaacata tacctctggg gataaaaaac tgtatgttga agaaaagaat
    71641 tttgataaaa tagcagaaat cctgcataag aatctttcta tagacaaaaa agatgcactg
    71701 aatattttag aggacggcgc aaaaaaagag ctgtatcaag ttgaatttgg tagctatggg
    71761 aaaaatatct cccaagaaac caagcaaaac atcgaagcgg acatgaaaaa agaaggtgtc
    71821 gctggtcttt attttgtcga ccatcaggct cggatgtatc caaatggcgt cttttcttct
    71881 cattttattg gatacgcagt tccagacaaa gatgagaatg gcttagttgg taaactaggt
    71941 ttggagtctg cttacaatga tatcttgagc ggtaaagatg gtaagattat ttatcaaaaa
    72001 gataattttc aaaatcctct gccaggtaca gtggcagaag aagaaaaagc tgtcgacgga
    72061 caagatatct acacgacttt agacagcaga ctacaaagtt atttagaaac actgatggat
    72121 caagtaaatg aagaatatca gccagaagaa ttgacagcag tcctgatgaa agcaaaaacc
    72181 ggagaaatct tggcaatggg acaacgacct actttcaatc ctgaaacaat ggaaggattg
    72241 actggaaaag atgctatctg gcgtaatttc ttggtacaag atagttatga accaggatca
    72301 accatgaaag ttttcactac tgcagctgct atcgaagaag gagaattcaa cgagaatgaa
    72361 accttccaat ctggaaaaat ccaagtagaa gatgctacga tcaatgacca tgactttggt
    72421 gaaaaaggtg tgctgaccat gcgtcaagct ctttcatggt caagtaacgt cgggatggtc
    72481 atactggaac agcgattagg cggacgatgg tataactatt tacaaaaact gggatttgga
    72541 caaagtactc attctggatt agatgatgaa gtaaacggtg ctttacctac attaaatatt
    72601 gtcgaccgag caatgagtgc ttatggacaa gcggtaggtg tgacgaattt ccaaatgatg
    72661 aaagctttca cttctattgc gaataacggt acaatgattc aacctcgata tatcagcaaa
    72721 gtggtggatc cccaaactgg agaagagcga acaactcaaa cagaagttct agggcaacct
    72781 ttttcaaaag aaacaacaga aaaagtccgt gaatatatga gagatgttgt cgaaagcgaa
    72841 aactacggta gtgcttatgg tgtatatagt gtacctggat acaatgtatc ggcaaaaacc
    72901 ggaacagccc aaatcgcttc tgatacaggg ggatatcaaa caggagatac agcctacctg
    72961 tattcgattg tggagatggt tccttctgaa gatccagact atgtcttgta tctaacaatg
    73021 aaacacccta agacatatga tcgaatggca ttggctaaaa tcgcaaatcc attgatgaaa
    73081 cgggcaatgg attttaaaga aactgaagaa gattcagata cagaaacaaa aacagaaaaa
    73141 gtatccgtag ccgattatcg taatcttgaa gcggacgttg cagcagctga tgctcaaaaa
    73201 agtggactgc aacctgtagt gatcggtaat ggtaaaaaag tacaaaaaca atctactgcc
    73261 aacggtgatc agttgatctc tggagaaaaa ctgatcctat atactggtgg tgataagctg
    73321 atgcctgacg taacaggatg gtcaaaagca gatatcatga agctggggaa aatcctcggt
    73381 attgaagtta gttttgatgg agatggttat tgtgtcaaac aagaacttgc tccatatgaa
    73441 aaaatcactg aagacaaact tagttttact ttagaagaat aagaagagaa ataggagaga
    73501 aaagagcatg gaatggacac aagcattgat tcccattgtc agcagttgtg caatgacaat
    73561 tgccgcaatg ccgctattta ttggttattt tcaaatgaaa aagcaaggtc aggcgattcg
    73621 tgaggaggga ccaaagtggc acaatagcaa agccggaact cctacaatgg gcggcttagt
    73681 gtttctgatc ggctctattt tgacaggaat ttgggttgga gcttggcaaa aacagctaac
    73741 tcctactctt ttcatcttgc tttttgtatt agcgttatac ggagtaatcg gctttcttga
    73801 tgattttata aaaatattca agaaaagaaa catgggactg aactcgaagc agaaattgat
    73861 tggacagatt ctagggggaa tcatctttta tcttgtttac cgttctgaag gttatccagg
    73921 tgtattgaat ttcttcggac tagatctacc tttaggaatc atttatggta ttttcgctct
    73981 cttctggctt gttggatttt caaatgcagt aaatctgaca gatggcatcg atggattagt
    74041 tgctggctta ggaagtatct cttttgcagc ttacggtcta attgcttggc atcagcatca
    74101 gtatgatgta ttaatcattt gcttaagtgt tttaggaggt ttactgggtt tcttcgtcta
    74161 caacagaaaa cctgccaaga tttttatggg agatgtcggt tcattagcgt tgggcggact
    74221 tttagcggca atttctataa tgctaaacca agaatggaca ttgcttttga ttggtttgat
    74281 ctatgttatg gaaacagcaa gtgtgatgct tcaagttact tcctttaagc ttacaggaaa
    74341 acgaattttt aaaatgtctc caattcatca tcactttgaa atgtgcggat ggtcggagtg
    74401 gaagattgat acagtttttt ggttgatcag cattgtgact tcgttgatca cattatggat
    74461 cgtttggtag gagatgacgg gaaatgaaaa aaatatcaac atatgaaaat aagaaagtgc
    74521 ttgtcttagg actcgcaaaa agcggagtaa gtgcggccaa attattacat gaattgggcg
    74581 cacttgtcac cgttaatgat ggaaaacctt ttgacgaaaa tccggaagca caagagctgc
    74641 tttctttagg gataaaagta ataacaggta gtcatccaat cgaattgttg gatgaagaat
    74701 tttcattgat ggtcaaaaat ccagggattc cctacaggca tcctttagta gcaaaagccc
    74761 aagaaatggg tattccggta attacggaag ttgagctagc ttacgaagta gcggaatgcc
    74821 caattattgg gattacagga acgaacggaa aaacaacgac aacaacgatg acaggactac
    74881 tactgaatgc aggagcagat caaggaattg cacgtttagc gggtaatatt gggtatccag
    74941 caagtggtgt agcgcaagaa gcaaaatcag aagataaaat tgtgatggaa ttgtctagct
    75001 tccaactcat gggaatcaca gatttccgcc ctcatatagc ggtgattacc aatatctatg
    75061 aagcacatat tgattatcat ggtacaagaa aagaatatgt caaagctaaa tggaaccttc
    75121 aaaaaaacat gacagaaaaa gattatctga tccttaactg gaatcagtca gaactacaag
    75181 aattagcgca aagaacaaaa gcacgcgtac tgcctttctc gacaaaagaa gtgttggaag
    75241 acggtgtgta tgctgacgat tactcaatat actataaaaa agaaaaaata atggaaatat
    75301 ctgaacttgg cgtaccaggt aagcataatg tagaaaatgc actagctgct atttctgtag
    75361 caaaattgta tggtatatca aatgaagcta tacgagaaac gttgcatttt ttccatggcg
    75421 taccacatcg tacgcaatat gtaggagaaa tccaaggcag aaaattttat aatgattcaa
    75481 aagcaaccaa tattttagcg actaaaatgg ctctaagtgg atttgaaacg tctaaggtcg
    75541 tgttattggc tggcggatta gacagaggaa atacatttga tgaattaatt ccttcattaa
    75601 aaggaatcaa agcaatggtc gtatttggcc aaacaaaaga aaagttgatg gatgctggaa
    75661 aaaaagcagg catcgagaca atagtaacag ccgattctgt agaacaagca gttcctttag
    75721 cattagaaaa cagtacagat ggtgatgtag ttttattatc accagcgaat gccagctggg
    75781 atcaataccc aaattttgaa actagaggaa acagattcat ggaagctgtg aaccgattaa
    75841 aatagaaaaa gtagaagcga gcgataaaaa atgaaaattt tggttacagg cggaggaaca
    75901 gggggacata tttatccagc tcttgccttt gtcaattatg taaagactca agaaccgaat
    75961 gctgaattca tgtatgtggg agcaaaacga ggtctagaaa acaaaatcgt ccctgataca
    76021 ggaatgcctt tccatacctt ggagattcaa ggatttaaac gaaaaatttc catgcataac
    76081 atcaagacgg tccgattgtt tcttaagagt atccgtcaag caaaaaaaat cctcagtgat
    76141 tttcaaccag atatcgttat cggtactgga ggatatgttt ccggagcggt agtgtacgct
    76201 gcagccaaaa tgggtattcc aacagttatc catgaacaaa acagtgtacc aggtgttacc
    76261 aataaatttt taagccgata tgtggatcgg atcgctcttt catttaaaga tgcggcttcc
    76321 ttttttcctg aaaacaaagc agttcttgta ggtaatcctc gagcacaaga agtagcagat
    76381 actaaaaaat cagatatttt gaaaacattt gatttggatc cagaaaagaa aacagtcttg
    76441 atttttggcg gtagtcaagg agcacttaaa atcaatcaag cagtatcagt ttttttaagt
    76501 gaatatattc cttcttctta ccaagttttg tatgcttcag gagatagata ttatgaagag
    76561 atcctaaata aaataaatcc tgaaatacaa aatattagtg tccagcctta tatcaaaaat
    76621 atggcagagg tcatggcttc cagtgatctg ctggtggggc gtgctggtgc aacttcgatc
    76681 gcagaattca cagctctggg gttaccggca gtgttggttc ccagcccata tgttacgaat
    76741 gatcatcaga ctaaaaatgc aatgagtctt gttcacgcag gagcagcaaa aatgattgca
    76801 gataatgaac taacaggtga atcactaagt cagacagtca acgaaatcat gggtgatgaa
    76861 gaattgcaaa agcaaatgtg ccgagcttct aaagaacaag gaatccctga tgcttcaaaa
    76921 cgtctttatg acttagtaaa acaaataatc aaaaaataaa ggcggtggtc ttagtgagta
    76981 agaaaaaaga accaaaaaaa ttgtctcatc cgtcttctga tgaaaacaat ttgactcctt
    77041 ggcaaaaggc taaccgaaaa tatctggcag aacaagagat gaaaaaccaa gagccaaaaa
    77101 aagaagacat aacattagat acaccccttt cagattctga agaagaaaaa acggttcaag
    77161 aggaacagca agaagaaagc cagtccgaga aaaaaatcga attttttgaa gagatcaagc
    77221 aaaagaaaaa cggtggacca tataacggtt cttttttgaa ccggctgccc aatttaaaaa
    77281 gtcaacggca caaagtacta tttcgtcggt tagctttgat catcactgta ttgggtatac
    77341 cgctgatttt tttgatctat tatgtttctc cttatagcaa attacaagca gttgcagtat
    77401 caggcaataa gacagtcaac agccaagaaa tcatctctga tacaaaattg tcattaggag
    77461 aaaatgtttg gggacagtat tttcatcgat ctacttatat cgatcgcctt aaaaaagcac
    77521 agccaagaat cgaaacagca aatatacatt tcaaagggat gaatgaattc gatttggatg
    77581 taacagaata taaagagatt gctttgatcg caaaaaacaa tcaatactac ccagtgattg
    77641 aaaatggaac agtattagat gaaaaagtag caaatcctac aaaaaatctc cctatcttgg
    77701 aagagttcaa agactctgca aaaatcaaag aattaacaaa gcaatacaat cagttatcat
    77761 cagaattaca aaaagcaatt tctgaaatca agtacacgcc aagagcaagc aataaaaatc
    77821 tgatccaatt gaatatgaat gacggcaatc aagttattgt aaatatcaat aatcttgcga
    77881 accaaatgaa atattattcg caagtagcca aagatatgga tgaaaaaggt gtgatcgaca
    77941 tggaagttgg tatcttctcg catccttacg gtagcactca agaaacggaa gaatcgggcc
    78001 aatcggaaga aacaactgaa agtgaagaaa atgcggatca aacaaacgaa tcaagtgaag
    78061 aggcagaaac gcaaaaagca caaacacctg gatcgtctag cacaaacgga tcatctgatt
    78121 caaatgattc aagtgaaaca agtcaaatag aagataatcc aagtacaact ccgtcaagtt
    78181 taaatgaaaa ttgataaaac aactttaaaa agtaagaatg tactttctaa aaaccagtaa
    78241 tttatggtag aattggaagc agtgaatata tctattaata agtatatttt aaaacggacg
    78301 ctagttgttc gcttgtatat ggaatagtaa gtaggaggga atcccattca tggcaaaaac
    78361 aggaatgtat gtaggccttg atattggaac gacatctgtt aaagttgtcg tggctgaata
    78421 tatcgacagc caaatgaata ttattggagt aggaaacgca aaatcagaag ggattaaccg
    78481 aggcattatc gttgatatcg ataaaacggt ccaagcgata caacgagcag tacgacaagc
    78541 agaagaaaaa gcaggtatcc agatcaaagg cgtaagtgtc ggtttgccag caaacatgct
    78601 tgaagtagaa aattgccagg gaatgattgc agttaacgga gattcaaagg aaatcaccga
    78661 tgaagatgtc agaaatgtgg cttcagctgc ccttgttcgt tcaatacctc ctgaacgtca
    78721 aatcgtgtca atattgccac aagattttac tgtcgatggg ttcgagggaa tcaaagatcc
    78781 tcgtggaatg atcggcgtaa gattagaaat gtacggtctg ttgtttacag gacctaaaac
    78841 gatcatccat aacatacgta aatgcgtgga aaatgccgga ttaatcgtca acgaaatggt
    78901 gattactcct ttagcgctga ctgaatcaat tctttctgac ggagaaaaag attttggtac
    78961 gatcgtcatt gatatgggtg gcggccaaac aacaacggct gttatgcatg ataagcaatt
    79021 gaagtttacc aatcttgacc aagaaggtgg cgaatttgtc actaaagata tctctattgt
    79081 attaaatacg tcatttaaca atgcagaagc gttgaaaata aactacgggg atgcataccc
    79141 agaacggaca tcaccagatg aagaatttcc agtagatgtg attggtcagt cagaaccagt
    79201 gaaagtcgat gaacgctact tgtcagaaat tatttcagct cgaatggaac agattttcaa
    79261 caaagcaaaa gatgcattgg accaaatcga agcattagag ttgccaggtg gcgtcgtatt
    79321 gacaggcgga gctgctagtc ttcctggtgt tgtggacttg gcacaagaaa tcttcggcgt
    79381 aaatgtaaaa ttgtatgttc caaatcacat ggggctgaga aacccggtat ttacaaatgt
    79441 aataagtatc gtggattatt cagcaaactt gagtgaagtg tatcaattgg caaaaattgc
    79501 tgttacgggt gaaacctcag cagctcgtca aatggtagtt gaacaagaaa caacaaacac
    79561 atatgagagc tatgaagcac ctgaagaaac aatctacgat gagccggaac caaaagagtc
    79621 cggagaaaat gtaaaaaata aaatcaaggg tttctttaca aatatttttg attaattcat
    79681 cctgggagga ataagatatg gaattctcaa ttgataataa tatcaatgac ggcgcagtaa
    79741 tcaaagtcat cggagtcggt ggtggcggtg gaaatgctgt aaaccgaatg attgaagaaa
    79801 acgttaaagg tgttgaattc attacagcca acacagacgt gcaagcatta aaaaattcaa
    79861 aagctgaaac agttatccaa ttaggcccca aatatactcg tggtttaggt gctggttctc
    79921 agccagaagt tggacaaaaa gcggcagaag aaagtgaaca atccttacgc gaagctttag
    79981 acggtgcaga tatgattttc atcactgcag gaatgggtgg aggaaccggt acaggtgctg
    80041 caccaatcgt tgcaggtatc gcgaaagaat tgggcgcatt gactgttggt gtcgtgacac
    80101 gtccattcac ttttgaagga ccgaaacgtg gccgttttgc tgcagaaggt atcgctcgtt
    80161 tgaaagaaaa tgtggataca ttattaatta tctcaaataa ccgtttatta gaagttgtag
    80221 ataaaaagac accgatgctt gaagctttcc gtgaagcaga taatgtttta cgacaaggtg
    80281 tacaaggtat ctctgatttg atcacagcgc caggttacgt taaccttgac tttgctgacg
    80341 tgaaaacagt gatggaaaac caaggtacag cattgatggg gatcggtgtg gctagtggag
    80401 aagatcgcgt agtagaagca acgaaaaaag caatctcctc tccattgctt gaaacatcta
    80461 ttgatggagc tgaacaagta cttcttaaca tcacaggcgg tttggatatg acattgttcg
    80521 aagcacaaga tgcttcagat atcgtagcaa atgcagcaac tggcgatgta aatatcattc
    80581 taggtacatc tatcaatgaa gaaatgggcg atgaaatccg tgtgacggtc atcgcaacag
    80641 gtatcgatga atcaaaaaag gaacgcaagt ctagccgacc agctagacaa gcacaaatgc
    80701 aatcacctgc tcaaaagact gtattagata tggatcaagc taaaccaact tcttcagaag
    80761 aagaaaacag ttttggcgat tgggatatca gacgtgaaca aaatgttcgt cctagagttg
    80821 atgattccaa ttttgacaat atcgaaaaaa aagaatttga tacattcaac cgcgaagaaa
    80881 caaaatctca tggcgatgat gaattaaata cgccaccgtt tttccgtcgt aaaaaataaa
    80941 ggagaggaag agcacatgat tgctgacaac ttgcagaaaa tcaagcaaga aattcaggat
    81001 tcgtgtgctc ttgttcatcg tgatccgaaa gaagttacat tagtagctgt aacaaaatct
    81061 gttgaatccg ctcaagctga agaattggtt agagctggcg ttatgaattg tgcagaaaac
    81121 cgagtagata aattattaga aaagaaacaa gatttatttg attttcctga aataaagtgg
    81181 catttaattg gtaatttaca gcgcagaaag gtaaaattga ttgtaaatga aattgattac
    81241 tttcatgcgt tggacagttt aagattagca gaagaaatcc agaagcggtt agagaaagaa
    81301 ttatcctgtt ttattgaagt aaatgtttct ggtgaggaat caaaacatgg aatttcacca
    81361 gatgagcttt taccgtttgt ggaatcttta gctgcctgca caaaaatcaa ggttgttggg
    81421 ttgatgacta tggcgcctaa agaagcttct gatgagcaaa tccataaagt gtttggtacg
    81481 ctgaaagaat tgcgtgatct tgttcaagca aaaggttatg cccatgcacc atgtagtgaa
    81541 ttaagtatgg ggatgagtca agactttcaa attgcgattg aagaaggtgc aacatttatc
    81601 cgtgtaggaa cagcgctatt caaagacgaa taaaggagga acaaaaatgc cgcttttaaa
    81661 cagaggagca attgctaatt ttttcggatt agctgatgag gaagagtacg aataccaaga
    81721 ttatcctgaa acaacaaaaa aggctgtaca gccaactaaa aaaaatacaa cacagaatca
    81781 atcaactcat tctgtatctg ctgcgaatac tcatgaaaaa caaaaaacgg cgacttcacg
    81841 tcctgtaacg catgaaagta ttcagccggc tgaaaagaaa aaagtaattg aactacatca
    81901 atcacctaca aaaactgtag cgaaagaaag aacagcttca agaacctcta cacaacctaa
    81961 agcaaatctt gctggaaaaa tcactgtaat ggaaccaaga gcttattctg aagctatggc
    82021 gattgctaaa cgaatcattg ctggagaagc aaccttagtg aattttcatt tagtagaaga
    82081 aaaacaagcg agaagaatcg ttgattttct aacaggaaca gtttatgcac tagatggaga
    82141 tatcaaacgt gttggagatg agatttttct ttgtacaccg actgggatgg agattgacag
    82201 ttcaaccgct caatcttttg cagatgcgaa tttgtttgat ctgtaagagg aggaactacg
    82261 atttatacta ttgcactatt acttcattta cttcaacggg cagcctattt ctatagcatt
    82321 atcttgatgg tatatgcatt gctctcttgg tttccaggcg ggtatcaatc agggctagga
    82381 cgattattag ctaagatctg cgaaccgtat atcagtttgt tcgatcgtct gcctttgagg
    82441 attggaccct tggatttcac aattttaggg gcaatcctga tcttgaactt agccgtacaa
    82501 ggtttagcac agatcgttat atggataact gtccatttag tttattgatt gaagcaacaa
    82561 aatctttatt ctcagaatag ataggagggg aaaattttgg atgcaaatgt ataccagcac
    82621 tttcgggcag atgaacgtac atttatcgat tcggtaggcg attggattga acaggttcaa
    82681 ggacaatatg caccctatct gaccgaattt cttgacccaa gacaatccta tattttagaa
    82741 acactgattc gacaaagcag tgatttgcgt ttcatgtttt atggcggata tgaacaggca
    82801 gaaagaaaaa gatgtttgat tttccccgat tattacgaac ctgtagagga agattttgaa
    82861 acagcattgt atgaaatcca ttatcctagc aaatttgcca gcctaagtca tgggaaaatc
    82921 cttggaactt tagtgggaac ggggatcaaa cgctcttact ttggcgatat catctcggac
    82981 ggtgatcgct ggcaagtatt tattgcaaat gaggtggatc attttgttgc tgcacaagta
    83041 acaaagattg gaaaggttgc tgtacgcttg gaaccaatca aatacacaga aatgattatg
    83101 ccgaaagata gctggacaca agaaagagga acagttagtt ccatgcgact agacagtgtg
    83161 atctctgaga tttataatat ttccagacag cggtccaagc agctgatcga agctggtaaa
    83221 gtaaaagtga actggacaga aaatacaaga cctgattttg tacttgaact attagatatt
    83281 atttcagtca gaggttatgg cagagtccag atccaagaac ttgaggggaa gacgaaaaaa
    83341 gaaaagtaca gggtactgtt cggtgtatta cgtaaataaa ataaaaaggt ggtttactca
    83401 tggctttaac tccattagat atccaaaata agacattccc gacaaaaatg cggggatata
    83461 atcaagacga agtagatgat ttcttagatt tagttgttcg tgactatgag gaattgactc
    83521 aaagaaatcg agaattagaa aaagcagtca aacattctga agaaaaactt gagtacttca
    83581 atgaattaaa agatgctttg aaccaatcaa tcatcgtagc tcaagatacg gctgataaag
    83641 taaaaacaag tgcaagcaag gaatccgaag tgatcgttac ttctgcacaa aacaaagcag
    83701 atgagttagt tgcgaacgct gaaaaacgtg cacatcaatt aacaactgat gcagaagaaa
    83761 aagcaagaaa aatcttgaca gatgcaacag aaaaagcaag acagcttgcg acagaaactg
    83821 aagatcttaa gaaaaaaaca cgagtattcc atcaacgtat cagcttgatg cttgagtctc
    83881 aattagaaca agtgaaaagt ccggaatggg atgaaatttt acaaccattc tccagctacg
    83941 tgactgacag ccatgaagtg atcaaagaag ttttagcaaa acagcttgac aatgaaaatg
    84001 atactgatgt aaactcagac acaggagtca tagaagcacc tatgacggca tttgatacac
    84061 aggctattga tatctcgatc gtgcctggtg aaaatgaaaa cgagtagaac agaaaagcac
    84121 tttgttattc ttaaagcgag ccgatgagag tggaagttcg gtaagacact gcatggtgaa
    84181 agatcctcta cttgagacct gcttttccga aattagagta agaagcagcg gctgacctcg
    84241 ttattggtca cagagagttt gcactagata gatgcaacta aatttgggtg gtaccacggc
    84301 atgttcgtcc cttgcggctg aacatgcttt tttgtgtccg gaaaacaaat aaaggagtgt
    84361 atggttgaat gaaaatgaaa gaaaccttgc aattaggaaa aacaaaattc cctatgcgtg
    84421 gtaatttgcc aaaccgagaa ggcgagtggc aaaaagaatg ggaagaaaat cgaatctacc
    84481 aaaaaagaca agagttgaac gaaggaaaac ctagctttgt tcttcatgat ggacctccat
    84541 atgccaatgg taatatccat ttaggacatt cattgaataa aatcagtaaa gacattatca
    84601 ttcgttcaaa atcaatgtct ggctatcgtg caccatatgt tccaggatgg gatacacatg
    84661 gattgccgat tgaacaagta ttggctaata aaggcgtgaa acgtaaagaa atgtccatgg
    84721 cagaatactt ggaaaaatgt cgtgaatatg cactttccca agtagataag caacgagcag
    84781 atttcaaacg cctaggagtt gcaggagatt gggaacatcc ttatgttaca ttagatcctt
    84841 cttatgaagc tgcacaagta cgcgtatttg gtaaaatggc tgaaaaaagc tatatttaca
    84901 aaggattgaa accaatttac tggtctccgt caagtgagtc ttctttagcg gaagctgaaa
    84961 ttgaatataa agatgtaaaa tctccatcta tttttgtagc tttcaatgtc aaagacggca
    85021 aagatattct tgatgaagat acagcttttg tcatttggac gacaacacca tggacattgc
    85081 cagcaaacca aggtattgct gtaaatccaa aatttacgta tgtattggtg gaagccgatg
    85141 gccgtaagtt tgtcgtagcg aaagatttgc tagaaacagt ccaatcagaa atcggttggg
    85201 aaaatgtaac agttctaaaa gaatttgctg gacaagaaat ggaatatatg actgcaagtc
    85261 atccattcta tgaacgtgaa tcacttgtga ttttaggcga tcatgttact ttagacgctg
    85321 gtactggatt agtccatact gctccaggac atggggaaga tgactatatc gctggtagca
    85381 aatataaact atctgtagtg tcacctgtag actcaaaagg attgtttaca gaagaagcac
    85441 ctggatttga aggtatcttt tatgacaaag caaatcctat gatcactgat ctattaaaag
    85501 aaaaaggagc tttgctgaag ctagatttct ttactcatag ttatcctcac gattggcgga
    85561 cgaaaaagcc tgtgatctat cgggcaactc cacaatggtt tgcatctatc gataaattcc
    85621 gtcagaatat tttggatgaa gtagaaaaag tagagtgggt tatcccatgg ggtaaaacac
    85681 gtttgtataa tatgatccgt gaccgcggcg attgggtaat ttcccgtcag cgtgcatggg
    85741 gagtaccact tccgattttc tatgctgaaa atggagaagc aatcatcaca ccagaaacaa
    85801 tcgaacatgt ggcaaaatta tttgctgaac atggatcaat tatctggttt gaaaaagaag
    85861 cgaaagaact tcttcctgaa ggatttaccc acccaggttc tcctaatggc gaatttacaa
    85921 aagaaaaaga tatcatggat gtctggtttg attctggttc ttctcatgaa gctgttttac
    85981 gtcagcgacc agaattatca ttcccagcag atatgtattt agaaggatca gaccaatatc
    86041 gtggctggtt caactcaagt atcacgacta gtgtggctat caatggtgta gcaccataca
    86101 aatcagttat ttctcaagga tttgctttag atggtgaagg ccgtaagatg agtaaatctt
    86161 taggaaacat cattgcacca gaaaaagtga tcaaacaatt tggtgcagat atccttcgct
    86221 tatgggtatc tagtgtagat tatgaagcag atgttcgtgt ttctatggat atcttaagtc
    86281 aagtggcaga agtatatcgt aaaatcagaa atacgatgcg tttcttatta gcgaatacag
    86341 aagatttcga tcctaaaaaa gatactgttt cgtacaatga tttacgttct gtagacaaat
    86401 atatgaccgt tcgattgaac caagtaatca aagaaatccg agaagaaggg tacgacaaat
    86461 ataacttcat gcatatttac cgtacagtta tgaacttctt gacggttgat ctatcgtcat
    86521 tctacctgga ttttgctaaa gatgtagttt atattgaagc agaagatgat tatcaacgtc
    86581 gttgcatgca aactgttttc tatcaaacag ctgtagcttt gacaaaatta ttgactccta
    86641 tcattccgca tacagcagaa gaaatctggt cattcctgaa agaagaagag gagtacgttc
    86701 agttaagcga gtttcctggt tatgaagagt ttgcaaacca agaagaattg atggatacct
    86761 ggactgcttt catggacttc cgtgataatg tcttaaaagc attggaagaa gcaagaaaca
    86821 gcaaattgat tggtaaatct ttggaagcaa aactaactgt ttatccaaaa caacaagttc
    86881 gtgaaatgtt aaaagctttg gatgcagata ttgcacaatt attgatcgtt tcaccagact
    86941 actttgaagt tatggcagca gatgaacaag tgccagataa cgctatggta tttgatgatg
    87001 ttgctattac agtggaaaaa gcagacgggg aaacttgcga tcgctgtcgc caagttcgta
    87061 aagatgtagg agtagatgaa aaacttcctc atctatgcgg tcgttgtgca aaaatcgttg
    87121 aagacttcta tcctgaagct gtagctgaag gattcgaaga aaagtaaaag ggaaaagggg
    87181 gtgtgacatg ttctttgtca cacccccttt tgttatcaat cgtttaattt tccacgttca
    87241 cgataccagt tatctggttg ccagatccat tcgaatccgt ctttttcaag tagttcgaaa
    87301 gctgctttag gtcccattga tccagctttg tagttgggaa aatccggttg tgtttggtcc
    87361 caagcttttc gaatgacatc cacgatatgc caagattgag cgacttcttc ccaatgagag
    87421 aagttcgttc catcaccatt caacgcatct aatagtaatt tttcgtaagc ttctgggcta
    87481 ttttcaacca tttctgcact atttctaaat tccaatttga ttggttccgt ttcaaatcct
    87541 tgccctactt ctttcccatt caaggataaa gaaaatcctt cagttggctg aatatagatc
    87601 gttagaacat taggtggaag tgtcgtatcg tcacatggtt catcgacaga tgttttgaat
    87661 acattaacag gaacttgttt gaatacgatg ttgatccgag tccctttttc agtcaaacgt
    87721 ttgcctgtac gtacatagaa aggaacacct gaccaacgga agttatcgat agtgaatttg
    87781 cctgcgacga atgtttcagt ctctgattga gcatccactt tgtcttcttc gcgatagccc
    87841 ttgaattgta caccatccaa ttcaccttga gcatattgcc cgcgaacgaa gttttctaac
    87901 acttcttctt cgttataaat gcggatagct ttcaatgctt tgatcttttc tgtacggatt
    87961 tctttttcgg aaaatgctac tggcggttcc attgcaagta atgctacaac ctgtaaaata
    88021 tgattttgca ccatgtcttt aagtgcgcca ctatgatcgt agtagccccc gcgatcttct
    88081 acaccgaggt tttcgccaaa agtaatttgg atattgtcga tatagcgatt gttccattga
    88141 gcctcaaaaa tattattggc aaaacggata gctgagatgt tttggatcat ttcttttcct
    88201 aaataatgat caatcctgaa aatatcttgt tctgggaata cttctctgat ttgctggttc
    88261 aattcaaaag cagactggta atcagaaccg aacggttttt ctatgatcaa acgattgaag
    88321 ccattttttg tcataatatt ttgtgatttc aaatgagaaa cgatcgttcc aaaaaattga
    88381 ggtgccatag ccaaataata gacacggtta ccgtttaatt gatagtgtcc atctaatcgg
    88441 tcagacaatt cttttaatgt ctgataatgc gttgaatcat ttacatcatg ggattgatag
    88501 taaaaatggc ttgcaaaggt agttgcttct tcatctgaag gattcaatgc acggattgtt
    88561 tctttgacaa cttcacggta gtgctcatcg ctccagggac ggcgagcggt tccgattaca
    88621 gcaaaatgct cgcctaaatt tccttttctg taaaggcgga acaaagacgg gtacaattta
    88681 cgctgggcta ggtcacctgt accgccgaat atcgtaaaca atacattttt ttcattagac
    88741 atgtggatac actcctttat attttatcga caaaaatcgt gctggccgcc ttaaagctga
    88801 cggggatttt ctttctatca ttttggatag tgatcggtcc ttcataagct gcgatgtcaa
    88861 cgatctcata ttcttcgttg atattcaggt caatagtgac taagtaatcc aacaattctt
    88921 tttcatcaag cactcgtgcg atacgcactt ttgtaccgac aggataggac tccaatgttt
    88981 gtcggcgttc ttcatggaca acttcctctt ttttaggaat cgatcctcca tgaggacaat
    89041 gttcaggatg attcaaatag ttttctaaat gatctgcaag atgttccgaa gtcacatgtt
    89101 ccaatacttc agcatcatca tggacttcat tccagctata gtctaaatgt tcaactaaaa
    89161 aaacttccca taagcgatgt ttgcgaatca gactgctagc tttttgcagt ccgcttgcag
    89221 tcaattgtac accttgataa ggggaatgtt ctacaagctc ttctttcaca agtttagaaa
    89281 tcatttcact gacagatgca gctgagacat ctagactaga tacgatttgt ttattgttga
    89341 ctttcgttgt atctccacct agttctaaaa tgattttcaa ataatcttct cgatttggtg
    89401 tcatattcga tcatcctttc atggtaaaaa accatcatta gtaagtgtaa caaaaaaaac
    89461 gttaattgac tatttttcta aataaaaaac aaaggatttt tagacgtttt tacaacaaaa
    89521 aacgaaagat gatagagaag actcattctt tcgtttataa aggatatata tatacattgg
    89581 gagggatcta tttttcagat aacaacttat atgaagtgtc tgcagattcg tcataaagag
    89641 tttgttcggg ataagaaaag ataagataaa aaccatactg atcacgtacg actaaacgat
    89701 attcatctat ttctaccaca gatgtgccaa gagactgacc gttgatcaaa aacgtgtaat
    89761 cagatgtaat ctgtaattgt tgtttttgct ggctatcact aaagaaccat gtaccttgat
    89821 actttgagag tccttctgac ttttccgctt gttttttctt tttcaagtaa ataaaacttg
    89881 agagaacggt aatgagtgaa ccaagaaaat agatcatttt ttttatcacc aaatcactcc
    89941 tttatgagaa aataatcgca tagacatatt ctttcttctt tatttcattg taccgaataa
    90001 aagctaaaat ttctctaaga ctttcgactg gtttttttac tgtttttcta caaattatga
    90061 taggatacat agtaggaaga aaggtgacat aatttgaagt atcagcaagt ggaaatagct
    90121 ttttttattg accgcccgaa tcggtttata gcacattgta tgaaaaaaga cggagaaata
    90181 attattgcgc atgtcaaaaa tacaggtaga ggaaaagagg tcctgatacc aggcgctgaa
    90241 gtggctattg tatttgctcc tggacctaaa cggaaaaccg cctatgatct gattgctgta
    90301 aaaaagaagg gtgactggtt taatatcgat agtcaattgc ctaatcggct ggcaattgat
    90361 ggtattttag acggcacgat ccttttacca ggattaactg gtccatttac ggtatacaag
    90421 cgtgaagtaa cttatcttca ctccaaattt gatatttatt tagagacggt ggtcggacaa
    90481 aaagcatttg ttgaagtcaa aggtatgaca cttgaaaata aagcgattgg tgcttttcct
    90541 gatgcgccca cactcagagg attgaaacat ataggagaat taacgtatgc cgcacaagat
    90601 ggttatgccg cttatgtctt gtttattgct cagttcgaac atcttcatct ggcaacgatc
    90661 catgaagaaa tgcaaccagc actagctgat atggttcgac atgcgcagca aagcggagtt
    90721 caaatcctcg cctataattg tcaagtatcg gcagatgagg taactgtcaa gcaggccatt
    90781 ccatttgatg tagatatccc ttttgaagat cctatacaat agaaagaagg taaaataatg
    90841 atcaacttag gtattatcgg aacaaattgg attactcatc aatttgtcca agcagcttta
    90901 agcacaaaaa aatatgaatt gacagcggta tattctagac atttggaaaa agcacaggaa
    90961 tttggttctc attatgaagg ggatatcgaa ttcgcaacag atttgaagac ttttttcaat
    91021 attactcata tggacaccat ttatattgct tctccgaata gtcttcactt tagtcaagct
    91081 aagcaagcaa ttttggcagg aaaaaatgtg atagttgaaa agccagcttt ttcgacgcca
    91141 aaagaaatgg atgaaatcat ccatttggca aatgaacaca atgtgtattt ttttgaagca
    91201 gcaagaaata tccatgaatc aggttttaaa aagattgccg attacttacc attaaaagac
    91261 gagataatcg gtgcaaattt cagctatatg aaatattctt cgcgctatga ccaagtatta
    91321 gatggagaag aaccgaatat cttctcgact catttctcag gtggtgcatt gatggattta
    91381 ggtgtttacc ttgtatatgc agctgttgct tggtttggaa tgccaaaaga agtccattat
    91441 ttcccaagaa agatttctac tggtgtagat ggtcttggat gggggatctt acgttatgag
    91501 aattttgatg tatcgatcca gccaggtaaa atcggtgatt cttatttacc gtcagagatt
    91561 tattttgact caggaacgct agtgatgaat ggagtcaatg caattgaaca agcacaattt
    91621 catgatcgcg cgcataaaga aatcattgat ttggcggtaa cagctgcaga aaatccaatg
    91681 gcagatgaag cagaggattt tgccaatgtc atggctcatc cgaaagatcc agcttgggga
    91741 ttgttgtatg aagagtggat cgagctagct agaaatgtga accaagtgat ttatgattta
    91801 agaaaaaatg gcggcatcaa attcgatgca gataatgagg aagattttta atgaacgaat
    91861 ttgtacaagt atttcccgaa aattggcaga aaaaatatga ggataaaggg tttatctcac
    91921 cttctcttat tcaacgagca gtttttcagc cactaagtaa taaacaaagt atagtagcgg
    91981 tttctcctac aggttcaggt aaaacactgg cttatctttg gcctctacta ctaaacgtgg
    92041 aaccaggtga agcaagtgcg ttggtcattt ttgcttcttc tcaagaacta gctattcaag
    92101 tagcagatgt tgcacgtgaa tggggaaaag acaaagagtt gaaagtccaa tctttggtgg
    92161 gcggagccaa cgtcaaacgt cagattgagg gtttgaagga aaaaccagaa atcttgattg
    92221 gtacaccagg aagaatattg gaattgatga aagcaaaaaa aataaaagca catcaagtga
    92281 aaacaatggt atttgatgaa gcagaccagc tatttgacgc tgggaacagc caaatcattg
    92341 atcaaattct tcatcaagct ccaacagagt atcagctagc ttttttttca gcgacagcag
    92401 atcgttccct tgaaagcatt gaaaaaatca ctgggaaaac gtttgagaca attgacgtga
    92461 cagcagagga cgattctcga aaaggactga gacattactt tttacgtgta ccgatacgaa
    92521 agaaagatga ctacttgaga cgtctcacgc atatagaaga ttttcatggt ctgattttct
    92581 ttaatcaact gactgaatta ggcgtaatgg aagaaaaatt gctgtataga ggtgtaccgg
    92641 taggaagtct ggcctctgat cagaacaagc tactccgaaa agcagcgcta gaacaattca
    92701 aaaagaaaat ggtcagagca cttttgacca cagatgtggc ggctagaggt ttagatatta
    92761 caggtcttcc ttatgtagtg aatgcagaag ttccgttaag tgaagaagct tatttgcatc
    92821 gttcgggaag aactggtcga atgggtaatg aaggaatagt aattacactc gtacaagata
    92881 ataatctaag agatttaaaa cggcttttac gtccatcaaa tataacactt gaagagattt
    92941 ttttatacgg aggtaagctg caaactgagc agccaaccaa agaagatgca gctcctgcag
    93001 taaataaaaa gtatgcgaaa actttttctg gaaaggagca gaacccagaa tataacaaag
    93061 aaaaaataag aaaaaaagtt aaaaataaat caaaaaaaga gagaaataaa ggagcaaggc
    93121 gcaaataagc gcctttttat gctatgatta tgaaaacggg aacaaaattg gttgccagag
    93181 gaggggttat gtgaaagaac gtcaagaaga gatcttgcag ctattgacag aaaaccaaca
    93241 aggattgaca gcaagtgatg tagctgagcg cttaactatc gatcgaagca atgcaagccg
    93301 atatttaagt gaactataca aggcccatca tattgtaaaa accgctggcc gaccagtcgt
    93361 ttactctttg ccaacggaaa agtcaaaatc tgatgaagtg catgtcgact cttctacgca
    93421 agtgactttt gaaacactcg ttggagaaaa tgattcttta aaagtcagca tacagcaggc
    93481 aaaagctgcg attctttatc caccgcgggg gttgcatacg attatttttg gagaaactgg
    93541 tacagggaag tcgatgtttg ctgaatgtat gtatcatttt gcaatcgatt cagagatgct
    93601 ttctgcagat gcgccatttg tttctttcaa ttgtgcggat tatgctcaaa atccgcaact
    93661 gctctttgga cacatctttg ggatcaaaaa aggggcttac acaggagcag ctcaagatag
    93721 tcccggtcta atagccaaag cagacggcgg tatattgttt ttagatgaga tccaccgttt
    93781 accgccggaa gggcaggaaa tgctgtttac tttcattgat aaaggtattt accgtccgct
    93841 tggagaaagt gcacaagtac atgaagcatc tgttcagatc attggggcga cgactgaatc
    93901 ttcagaaagt ttcttatcta cgttcaatcg acggattcct atggcaatca ccttgccgaa
    93961 tcttgcttca cgttcactgg atgagcgtta tgaaatcatc tctcttttta tcaaacaaga
    94021 agcgaatcgt ttgaatcaac gtatcgatat cgaaaaagaa gcgattcttg ccttcatgct
    94081 ttatgatgcg gaaggaaata tcggtcaagt gaaacgagac ttgaaactag tctgtgcaaa
    94141 atctttttta cattaccgta ctcatcatga gaaaaagcta atcattcgaa aagaagaact
    94201 ttcccttcaa gtacaaaaag gattactgaa aatcaaggaa ataccggaac gtctcgaccg
    94261 attcatggac agcaaaagtc agtatttgac atttgaacca ggatttgctg atgttgtctg
    94321 gtcacaagat ccagaacgaa acatgcaggt ctataacgat attgaggaaa aagtcacttc
    94381 tctttccgaa accggtgtgg agaacattga tctagagacc ctcatttcaa aagatgtgga
    94441 tgcttatttc cagacatatg tcaaagaatt gactaaaagt tcgattccca aagatctttt
    94501 gccagatgaa atctggcggt taaccaatca attgtatgat gtggctgaaa aacggttaga
    94561 ccgtatttat aatgaaaaag ctcgttttgc ttttgctttg catctgcaaa gtacattgga
    94621 tcgtgtgaga gaaggtcata tgatcgtcca cccagatttg aataacgtac ggaaaaattt
    94681 taagagggaa ttccaggtag caatcgatct ttcaacgatc attgaagaag aagaacaagt
    94741 tgagattcct tttgatgaaa tcggctttat tagtatgttt ctttctatca atctaggaga
    94801 aagtgagcct gttaaagaaa acaaagtaga tgttctcata ttgatgcacg gcagacagac
    94861 tgcttcaagc atgttggaga tggcacaaga actattagga acaaaagtag ggaaagcttt
    94921 taatatgcca ctggttatgg aagttcaaac aatgtatgaa gaagtgttac aatatgtcaa
    94981 aaactatcaa gagcatttga cgaatggcct actcttgtta acagatatgg gatcattaaa
    95041 caccttcagt gatttgattt atgaagagac tggcattcgg acgaaagcta tcacgatgac
    95101 aagtaccatg attgtgatag aagcgatacg gatggcaagt gttggaagaa gcttagaaga
    95161 tatttatcaa aatatccagc tttcctttga atcgatcgta cgtgatcagt tcaaagcgga
    95221 aaagtctgaa actttacagc gtaaaaaagc cgtaatcgtg acatgcttta ctggtgaagg
    95281 agtagctgcc aaattatatc agcgtattat gccagtgatt aatcaaaata aggtagaact
    95341 gatccagatg cagtttttag aacgtgaatc attcaaaaaa cacatcgatg ccttattgga
    95401 agaatatgag atcaaagcaa ttgcgggaac agttgatgtt gattatcaaa atatcccatt
    95461 tttttcagcc tatgacgttt ttgatgatga aaaactaaat attttaaagc gtatagctga
    95521 tgatgagatc ccgacagcta aaattgtcga ttcacttgct ggatcattaa gcgatgtctt
    95581 ttctattgat gaactgatcc gttcattgca aaagacagtt cagcagatcc agaccgattt
    95641 gtcgattatc gtggaacctg gagtagatac tggaatcgtt atccatttag ccttcatgtt
    95701 agacggattg atcaaacaag aaagccatcg gcaatttgag aaactgtcta ttttctcaaa
    95761 aatttatcgt ttggaaatgg atatcgttcg ggcaaacttg atggcactag aacgaaaata
    95821 tcaggtaaaa attccagaag atgatatcgc atttcttaca caaatgtttc ttgaaaataa
    95881 aataaaaaaa tgaacacact aatcatactg tttacacact aaacatctgt gtgcgcacta
    95941 taaaaaagag ctaaaaagca tgaaaacgct atttcagctc ttttttttat tggcatgctt
    96001 cttgcgttat ataaaagtgt aaaaaaataa aaggagtgtt aaaaatggca aaaaaaacaa
    96061 tcatgttagt ttgttcagca gggatgagta cgagtttatt ggtcacaaaa atgcaaaaag
    96121 cagcagaaga aaaagggatg gaagccgata tttttgcggt ctctgcctca gatgcagata
    96181 ataatttaga atctaagaat gtcgatgtat tattattagg tcctcaagta cgtttcatga
    96241 aagctcaatt tgaacaaaaa cttgcgccta aaggtattcc attagatgtc atcaatatgc
    96301 aagactatgg catgatgaac ggagaaaaag ttcttgcaca agcagaaaat ctaatgaaat
    96361 aaatcaagta tgcagttggg ggtataacaa cgtggaagat caacaaaatc tagaagccat
    96421 catggggtta atcatgtttg gcggtaatgc aaagagcgat gcaatggaag cgattgcggc
    96481 tgctaaaatc ggtgattttg agttagcgga taggaaaatc gctgatgcag aagaatcact
    96541 tatacaagcg catcatgcac aaacagacat gttgacacaa gaagcacaag gaaatcatat
    96601 gcaagtgaca ttattgactg ttcacagtca agatcactta atgacatcta ttgcgtttac
    96661 tgatttagca aaagaaatca tcgaacttta tcgtcgcgta tacagcgaat aaatacaact
    96721 tcttttttga acggaagaag aaaaattttt gaacggattt tttattttgt tataaggaga
    96781 actctcttta tataaaaaac ttataggagg aagtaaaaaa tgaacggact atcaagttgg
    96841 atggagaaat acatcctgcc ggttgccgca aaaatcggag cgcaaaaaca tttagttgct
    96901 ttgcgtgatg cttttatcgg cacactgccc gcaacaatgg cgggatcagt cgctgtaatg
    96961 atcaatgcaa ttattcgtga tttaccgcaa cagtttaaca gtacctatgc tgacagttta
    97021 gcagcagaca aaggaatctt tgccgtattg aatgtcatca tcggaatcaa tggttttgtc
    97081 tggaacggta cactagcaat cgccggattg atctttgcct tttcttgggg gtataatctt
    97141 gcccgagctt atggagtaaa tgatctagct ggggggatcg ttggtttagc taccttgatt
    97201 caaggtattt cctttggtcc agcattatca gcagcattag atgtgaatgt tccttcaaat
    97261 gtcgcagatg caatcaatag ttctgagatt ggtgcaacga ttgcagatgg cacactgtca
    97321 gttggattat ggggttggct aaaactagat catttgaatg gaaacgctta ttttacagtt
    97381 atgatcatgg gagctatttc agtcattatt ttttgtaaat tgatgcttgc caacattacg
    97441 atcaaaatgc ctgattcagt accaccagca gtatctaaag catttgcagc cattttacca
    97501 gcgacgatcg ctttatacgt cattgctatt atcaattata tcgtaggtcg tgtagctgat
    97561 gggcaactga tcattgattt ggtgcaaaaa tatattgcag aaccattcct aggattatct
    97621 caagggttgg gagcagtatt gatcgtcaca gtatttgttc aagtattctg gttctttggt
    97681 attcatggac caaatgtatt ggcaccagtg ctagagggaa tctggggaca agcacaacta
    97741 atcaatattg atattttcca aaaaggttat aacggaaaaa ctggtacacc agccgtgtta
    97801 gatgcaatcg aagatggaaa agcttatatg tgggtccgcg gatcgttcga tgcttttgca
    97861 tggtttggcg gatcaggcgg aacgatcgtc ttactgatag ctatcttgat tttctctaaa
    97921 cgtgcagatt atctaacagt agctaaatta tccattgggc ctggtatctt caatatcaac
    97981 gaaccagtga tgtttggtct gccaatcgta ttgaatgcaa tcatgtttat cccattcttg
    98041 attgctccag tagtagcaac agcaattgga tggacagcta cttatcttgg cctagtcgct
    98101 ccggtatcgc agcaagtcac atgggtagta ccgccgttct tattgtcatt cttagcaaca
    98161 ggagcggatt ggcgggcacc gatcgtaaca ttagtatgta tggtcgtgac tttcttgatt
    98221 tgggcaccat ttgtcatctc tgcaaacaaa atggaccctg ccgcaggcga acaacaataa
    98281 gatgaacgtg aggagcggga cgctttaagt ttcgttcctc ataatgaatt ttcgaggagg
    98341 aactgaaatg attacaattg ccagtgcaat gcaacaagat gaaatcaaag aattgttaga
    98401 aggatacaat gaagaaggaa tgacttttac atttaaagaa aaacaaggaa tcaagctgtt
    98461 ctttgaaaca agtgcagaag atccggaagt tgcggctaaa aaagcaaagg aactaatcaa
    98521 agcacagcct tggggaacag tcctttattt tcaatcaaca gctgtttaga aaatggttta
    98581 aaaagatagg atggttgaga tgataaaaaa cggtttattt ttatgtagta ttggttcttt
    98641 gatcgtgttg tatagtttga atccacattc gcaaaggtat gatttgtata gtatggtcac
    98701 aggtcttttt ctaacaggat taggaatcta tttcttcatg aaggggaaaa aaagagaaga
    98761 agcaaaggag aaaaataact aatggaaatc acgaaaaaat taaatattcc agcatcgttt
    98821 ttttacgata aagttatgga ctctgtcctt ttcgatgtac gtaaagcgac cggcaaatca
    98881 gtaactagaa aacagctgaa aaatttggag tacgtcaaac aattctcgca aaataaccgg
    98941 gctcgcataa aaatcgaaga agtcattgaa aaccagtctt ataagtttcg tacatcgaca
    99001 acgaagaatg aattcgtcgt tcattatcaa atcaaaccat tggacgattc gacctgtgag
    99061 gttcattaca cagaaaaaat ggagtcttat ggcatgcttc aaaagttgaa tgatatgctt
    99121 ttaggaacaa tcttgatgta ttttaaacgg agacgtttca aaaaaatgct agatatgatc
    99181 gaagcaacgt attaaatcaa tgaaacatgg tactatttag ttattgaaaa atgaagtaag
    99241 ctagaaggaa tttttcatag gaagatagat ctttcctgcg aatcctcact agcttttttg
    99301 taggaagggg cagcaaaatg acaaacaaag taagagagct aggtgtatct tcgattgagg
    99361 aaatgtttga tttagccact tatgcattta atggggcaga tacacctgaa aggcgagaac
    99421 gttttcgtac acttgcggag aattcttgga attacggatt ttttgatgag gaggatcggc
    99481 taacaagtca agtcatggcg accccttttc cagtgaattt ttacggacaa gagtacctaa
    99541 tggccggcat tggctatgtt gcttcttatc cagaagcaag gggacaaggc gggatcaatc
    99601 agatcatgga aaagatcctt gaagattgcc gtgatcgtaa agtaagctta tcttatctgg
    99661 cgccattctc ctatcccttc tatcggcgct atggctatga acaatcattt gataaaatca
    99721 gttatcaact aaacagtcgt gatgtgccgt ttatcaaaaa aaaatctgga aaaataaagc
    99781 gtatggattt tgaagatgca aaagctgcaa tcagaagaat ttatgaacag atgccggaaa
    99841 accaacgagc tggtctgaag cgcgaagact ggtggtatac gtataaattc aagcaaaaag
    99901 gcaattacca gtttgctttg cattttgatg ataatgagga agcaacggga tatatcgttt
    99961 atcagcttgc aacgtcttcc tttattattg cggagtgggg atttttggat catgatgctt
   100021 tttgcagcct tgttcgcttc gtaagttctc acaatggtgc ttttgaaaca tttgaatatt
   100081 catgcggcta cggcggtaat gatcaaaatt atctattaga aaatccattt gcttctgtaa
   100141 tgatcacacc ttatatgatg gcgaggatcg tagatatttc tttgtttttg gaaaattatc
   100201 catttaaaaa gagacaagct gcatttgccc tacaaataga agaagatcat tatgcgaaat
   100261 ggaatgaagg aatcgtggaa gtaacaatcg aaaatggaaa aaatcatctc tcaaaagtag
   100321 aacaaacaaa actcccaatc gttcgaggaa gtatccaaca tatcacgcag ctattattag
   100381 ggtatcgtaa agtggaagag ttggtattcc aagaaagaat acaggtgaca aaagaatatg
   100441 aagaaacgtt aagctcaatc ttgccacagc aacagccaat tcttaatgac tatttttgat
   100501 aaaaaacggg tgatgacaat atttttgtca ccaccctttt gtttttcatt tggcatttga
   100561 aggaaaatgt taaagtaaat cctctttttt cgtaaatttg aattttttgt tttcttttgt
   100621 tttagggttt tcttttttgt ggtcttggat tgcttctttc gtaatctttt cccgattttt
   100681 tttagatgaa tctaagcgtt ctgcgtatac tttttctttt ggcttatcat tcattggaaa
   100741 ggacctccct acattatttc attctacctc tagtttatca tctgttaagg actagtggaa
   100801 acgttttgcc taacttataa gctgattttt ttagcagata agcttgcaag taaaaaacaa
   100861 acaagctaca attgatttat tgaaattgtt cctgtagctc agtaggatag agcaatcgcc
   100921 tcctaagcga taggtcgctg gttcaattcc agtcaggaac gtataaataa cccctgtatc
   100981 ctttgcggta caggggtttg ttttgtattt gtgccaaaaa tgtgccaaac tagttatcat
   101041 ttttatataa actatcgaac acagtattga ttttttcttt atcctgatct tcaagctctc
   101101 gaacaatatg aagataagta gacattgtag tttctaaact gctatgtcct aaacgtttcg
   101161 atacgctaag tatatttact ccttgataaa gtaaaataga tgcatgtgta tgccttagtc
   101221 catgcaaagt aaattgcttt tcaatcccta attcttttaa ttttttgcgc aaatatttgc
   101281 tgacggcgtt tgatgaaact aatccatttt ttaagttgaa aaaaacaaaa ttatgagggt
   101341 ttttgatttc aaaattctcg aataattctt tttgattgat tttaaacttt tttaagagat
   101401 caatcgtatg tttatcaatg gaaattttcc tatttgaagt ttcgtttttt gtttttcccc
   101461 attcatttaa tttataattc catgttttat taatagtgat gatttgatct tcgaaatcga
   101521 tatcttccca tgttaatcct agaagttcag caaatcgcat tccagtggca ccagcaacta
   101581 acacgagcat aggagaagag tactgcgcag aaaggttttc ttctacgagt ttcattaaag
   101641 atttaaattg atcataatct aaatatttat cttcttttgg cttcaatgaa tcttttcctt
   101701 tgattactgc ttttctagtt ggatcaaacg gaattaatcc ttcttctacg gcatctttca
   101761 acgacgctct aatatggtta ttaaacttaa taacggtaga ttttacatgg tctttagcat
   101821 acttatttaa aaagcgttga tatcccactc tatctaaatc agaaatcaat accgctggca
   101881 tatatttctt tatgttcatt aacgtatctt cgtattttct ataagtgata ggagatactg
   101941 ttccttcttt ataaagttgc atccaatcct caaagtaatc tgataataat agatttttgc
   102001 gatccccttt aaggcctttg ttcaagttat attctaattc gttggcggca tcttttgctt
   102061 ctccttttgt cttaaatcct gattttctta tcttcgtgta ttttccgtca tcttttttgt
   102121 atgaaatttc gtattgccaa ctatttccac gtttgactaa tcttgccata attgaatcag
   102181 ctctctttct ctgatacaat aggaactata aagaagccca ttgtttgggt tttattattt
   102241 tttgcacatc ctttttgctt gccggcgcaa ggatgtgcta tttgtcgttt taatggtata
   102301 attggatgtg tattagatca tccaatcaga ggtgtttatt atgattaaag tgatttttaa
   102361 aagaataact gaacttccag agtttagatt atttgttgat tattggtatg tctggttttt
   102421 tattgttgca ttgctgatag gtctagatgt catattagaa agaaaactta agtaagagtt
   102481 gagttaataa attgaattcc taaatgagat attttgtagc ccatattttg tttgccgaca
   102541 tcacctaata ctatggagct aatcgttttt tctaacagac caaaatcaga taatctattt
   102601 aagctaccat ctattagctc ttgtgaatag ccagacatgc tgatatttcc agtgaaattt
   102661 tcgtttccac gactcattaa gcatgctaac aattgaatct caatcgatgt taattgattc
   102721 agtacaagaa gataatactc ctcgttatcc catgaagcgt tgttaattcg aagtaaacaa
   102781 ttcttataaa gatttttata catatctatt ttattttgtg cctttgattt ttctacctcg
   102841 tcatttatcc cttcgaatat tccaatgagt tggtccttgt tctctaagtt gaaaacatct
   102901 tctggaattt gatcgcgaat gttttctaat gattcgttta aatttttgta gaatttctcg
   102961 atgcgtttga aacgcttctc gtttttagac ccaaaataaa gtgactgcac aacgccacca
   103021 atataaggaa ttgctccaat accgccttca actattaatt caagatattc ttttttggtt
   103081 agtttttcat tgctattatc catagttacc tcctattttg tcatttcctt tacaagcatt
   103141 gtgactcctg atggcactct tttgtatagg ttttattatt gtgcacaatc taactcttag
   103201 tggggcgtgg ttcatttatt ttttacttac tttactatta atcatatccc attgagcata
   103261 ggatttttct atgttcgatc ctcttgaact aatttctcct gtaaaagtta ctttatcgcc
   103321 ctttgtaaag gtatcagcat tgtttaagtc cttcgcaaaa attacatatg aaactttagg
   103381 tgttgcagaa atatcattcc aacttttatc atcgtactct ttgtctgcta taatggctat
   103441 tctagtagtc attgattcga taacagttcc ttcaaaagta tatgttttac cactaatata
   103501 tttagtaaaa gctgtatttt gctcagtagc tggagtaata gaataataac tatctaagaa
   103561 agcaccccag tcatgattat ttgtctctaa aaattcttca aattgagtta ggcttttatt
   103621 gctgctgtta gatgtagtag tttgagtatc agatgatgag ctttcctgtt tgttattgtc
   103681 atttgcctcg tttgatgagg aaagcgagaa acctacggta gtaaaaataa tcccgataat
   103741 aaggagaatc ataggtgttt tcttatttgt ttttttgata aatcttacaa ttaacatgat
   103801 taaacctata ataaataaaa caataccagt aaaaccaaat ataccgtcca ttaatagatc
   103861 ctctttctct tttgatattg aatattataa accaagcaat tcttttttct taaaatcgaa
   103921 ttcttcttga ttaataatcc cttcatctaa caactcttta tactttttaa tttcatctgc
   103981 acttgaaatt tgtgtttctt tggaattatt atctaatata gattgttgct tctctatata
   104041 tttttttaaa ttttccattt cattccaata tttttttgta aacataacgg tgttttcatc
   104101 tttcgtggcc gctaatatac ctccgcgact ttcgtttccg cctagcaagg taaattgtat
   104161 ataaccatta ctcatacctg gtttttttaa ttgtacggct gatatatttt taaaggggat
   104221 agttttttct cctttaatac cttgattaac taaatttata aatccttttc taataattga
   104281 aatagaatca tcagttactt taatcaaggt ttttcctgga gattttatta aaatctcttt
   104341 ttccattttt tcttcctcat ttctgtgata tgattttttt tgtagaagct catatatgag
   104401 gaaagagccc gtgttgcagc acgggctttt ttaatgtttt gctgaaatcg gtttttttaa
   104461 taattcttga tgtattcata catattgcct tgcgtaagaa tattttttct taaaatagca
   104521 ttggcagaca gcataacaag tgtatctgag cttattctga atagaataat actccataaa
   104581 tttttcgaga ttaaactgag attcatcagt cagttcgttc tcaatataga tatttaataa
   104641 aattagaata gctattttat ctgcttctgt ttcaaatttt gagtgaaaag ttgtagaagt
   104701 atcgtacaaa actgaaaatt caaaatgaga ggcgctgaaa tgtgcaagtt catgagataa
   104761 atgaaaggct tctgcagttt caccgtatag attttcattc aaaaaaatga ttctgggttt
   104821 tggatagtag aaaccaggct ctttcatctc catataaact actttcaaat tgtattcgct
   104881 caacatttct ttcaatttca aatacataca aaccatcact ccaactattc attttcctct
   104941 aaagctttag caattgcaat cgctttacgc attgtctcct tagatatttc ttttccatca
   105001 aaagaaaaaa cagtatcgtc ttctgataaa tccacatgtt taggggtttc tctttcttct
   105061 ctacctagaa ggtagtctac agagacatcg aaatagtcag caatccgact taattcatct
   105121 gaattaggag tattattttt ccactttgct agataaccgt tagaatatcc aaaattaatt
   105181 tctaactgcc gtatagatat ctttttcctc ttcgccaagt cttttattat ttcataggta
   105241 ttcatcgata aaacaacctt tctaaatgtt tacaaaaaaa gtttagaaaa atacgcagaa
   105301 ataatttgac taattctgag taatgagcta tactatatct tgtaaacaga tttaacaact
   105361 aaaaagacaa caaaaaacac tattgatatg taaatgcaga ccgccaagaa agctttaaaa
   105421 tcaatgtttt tatgtcttat ttaattatgc tcttagtata gagtattact cagatactgt
   105481 caattgaatt tagaaaaaag ttgttaaatt tgtttacgaa tataaaagaa aggaatgaga
   105541 aatatgaaca caccgcaaat ttttaatttc gaacaaaacg aagttcggac aattttagta
   105601 aatgatgaac catattttgt aggcaaagac gttgcgagtg ttttgggtta ttcaaacact
   105661 aaagatgctt tgtcgcggca tgtagatttg gaagataaga tggggtcgcg aatcacgacc
   105721 tcaggtcaat caagagagat gacaatcatc aacgaatctg gtttgtacag tttaatctta
   105781 aaatcaaaac ttccctctgc caaaaaattt aaacgttggg taacaagtga agtgttgcca
   105841 gcaattagaa aacatggagg ttatctaact ccagaaaaag tagaagaagc tttgcttaat
   105901 ccagatacaa tcattcaatt agcaactcaa ctaaaagaag aaagaactgg aagattaatc
   105961 gcagaacaaa agattgcaga gtacgaacct aaaatctcct atttagatag catattatct
   106021 tctacagatt cagtaacaat tagtcagatt gcagcagatt atgggatgtc tccacaacag
   106081 atgaataaat tacttcataa actaggtatt cagaaaaaag tcggtaacca atggttattg
   106141 tgcaaaaaac acatgaacca aggatacaca aaatctcata caactgagat cccgaaagcc
   106201 gatggtggca ctaaaattgt aatgaatacc aaatggacac agaaagggcg tctatttatc
   106261 tacgaattac taaaaaaaga aggatattac cctcaaatgg atttagagga aattggttag
   106321 aaaggagttt tagtatgact gacattgcag aaatcactca acgagataga gaaaaaatca
   106381 aagaatatgt cgaaagttca aagttcttaa cttacaccat gcttgctgaa agatttggaa
   106441 ttagcaaaag ctacttatct ttaattttaa acggtaaaaa gacttctgca gaagcaaaca
   106501 gaattataga ttcgattatc actatgtacg aattgtaaag ggaggaacag ctaatgcaat
   106561 atctagaagc aaaaatccca attccagaag gctatgtaat tatctcccaa gtggattatg
   106621 aggagttaaa aaaagctgat gatactggta gatggatgac gttgccagaa gtgctagaac
   106681 ggattaacag aaaatatgat tggtttactt ctagagtttt aaagaaccca agatatagaa
   106741 atattatcga tatcgagaaa aacaaaaatg gatttgtcta ttatccagtt gaaggaagag
   106801 acacatatct atttttaaga agtaaaacac ttgaattttt agaaacaaat ttttcggaaa
   106861 tcttaaggag gcaagcggat gggaaaattt aatagagcgc tagtgttcag cgcaccgcta
   106921 atcatctacg ctttagaact ttggggaagc aggcaagcgt tgataggaac gattgtttac
   106981 atggtttgga tttttatggg gcttgatgaa gctgaagctg agtacagagc gaaaaagcca
   107041 accgaggggg ctgactaaaa atgaatagaa aagagaaact agaatgtata ttactattac
   107101 tcagtttaat tctttcacta atttctctat tgggaagttt gtatttttga tatcaacaat
   107161 tttgtggatt tgggttctat ttagagtaaa tatcattttt gtttggtgat taaggagttt
   107221 attaaaatta attttcccta cttcaaatgc aaggtaacaa gatatagcac ttttaggagg
   107281 aatatttagc ggtacagctt cagagtatat tctattatca tcgactgatc ctcctttagc
   107341 aattaatttc ttaaatggag tagctgacca tctgcggttt aagttagcgg atgaaagttc
   107401 taaattaact aacatagctg gttctgttga atagttagaa atgattactt ttgtataaat
   107461 catatctgca gcgaagtaag aagcattaag ttcaacttct agttgagggc gcattccttt
   107521 tatttttatc cctgttaaaa acgtactcaa tataaaactt attattgaca tccattgaaa
   107581 aattgttaag tgaaaaaaat tcaaaataaa caccaccagt ttttaactaa attataccaa
   107641 aaaggagaga agaaataatg caagaattag taattttgaa aaataaagaa gctgtgacta
   107701 cgagcttaca agtggcagaa agcttcgaga aaaaacatca acatgtttta agagatattg
   107761 atgcactaaa aaaagatgtg tccaattttg gacagatgtt tgtagaaggt aatgaaccag
   107821 attcatatgg cagaaatcga cgagttttct tcattagtag agatggattt ttcttgctgg
   107881 ctatggggtt tacaggaaag aaagctatct acttcaaaca aaaatacatt gaagcattca
   107941 acgaaatgga agatgttatt cgcaagaata ctgttcctca aacaattgaa gatatgatga
   108001 tctatcaatt agaagaaatg aaagatgtta aaaaagatgt ttccatgctt aaagatacta
   108061 tgcgaattag cggacaacaa gagtttgaaa ttaagcaaaa aggaaatatg aaagttatgg
   108121 gagttctagg gggaaaagaa agccgagctt atgaagaaat cagcaaaaaa gtattctcaa
   108181 aattttggtc tgaatttaaa cgtacctttt caatcccaag atatggcgag ttacctcgta
   108241 agagattcga tgatgctgtt tcatttattg aaatgtggtt gccagaaact gcgatccgta
   108301 tggaaattga tcaactgaac agacaacaga gactttttgg tgatgacaat gaatagagct
   108361 gaagcgctaa gaatagggac ggcaattgct aattgctggt ggaaatacta taaaccaatc
   108421 atcctaagcc aacaacatat tgacaagcaa aaagcatggc aacaaataaa aaagtgactc
   108481 cgccggcaag caaagagtca caaagaaaac acatcataag gagattttag catatggaaa
   108541 aagaactttc cactctagat caatatttga ttgatcctga ttggggcaag ccgaaaattg
   108601 aggaaacaag tggtcgaaaa atcagacgaa atcttttgac gaatgaagaa ctagcttggg
   108661 atcaagatga tttaggcaac catgtaacta tttgggatca tgtttatctt atccatctat
   108721 cgaagcattc gaataaacct gaatatattt acgtcatcga agatggcttg attgatgcgc
   108781 tagaagagta cgacagagat aacttgattg atatctctta ttacggacca ggtaagaaat
   108841 acattgctga aatggaggca gaatttgatg agtgaaatca aagggacaac gaactttgaa
   108901 aaacttttta gtcgtaagtt aaataaaatt ctcaagaaaa aaggaaattt tgattattta
   108961 tcttgggctc acgcgtggga gattatgaaa aagaatgatc cacaggcaac ggtaactatt
   109021 aatgagtaca aacactacag ggttgtttct ggaactcatc aagactttct tgttgaggaa
   109081 tataaacctt ttcttatgga tgaaactggg acttatgtat ctgtctcagt aacggttaaa
   109141 ggacacacgg aaaccgaatt atttcctgtt ttagattatc gaaaccaacc agttgttaaa
   109201 ccaaatgcaa tgcaaatcaa taactcattg aagcgatgct ttgtgaaagc attggctcta
   109261 cacggactgg gattatatgt atttcaaggg gaagatattc caacaccacc tagaatcgat
   109321 acaaagaaat taaacatgct agagacgatt ctagaagctt tcaatgagca gatgggtaaa
   109381 gatatgacca aaaccttaat cgaatatgtt aatgagcaga cagataaatt agggctctta
   109441 gctgataacg ttgaaactat tgaacagtta agctatgagc aatgtgcctt gatggagcga
   109501 gcaatagcag ctaagagaaa agaattagat aagaagtgat atgagtgttt aaaccattaa
   109561 tcgattcata ttcagcggtt ctgaaaaagt tcaaaggaaa agacataagc gcaaccatca
   109621 atgaggaagt gaacattgat cgactaaaga cgatgtatga cggctacgat ggtgatcgag
   109681 tcattgaaat tcgttttatt gatcctagac gtttcaccgt acagcaacga aacttcatct
   109741 atgcgctgat aggcgatatt tttatcgata caggcatgcc aacggacttc tggaaggaat
   109801 tcttctactt tcgttttgaa ggtgtcacag ggcgcaaaat aagcctgaaa gacgaatcga
   109861 atacaactgt gagtgatgcc aatgtcttag caaatatcat cttagatttc atctttgaac
   109921 atcatattcc tttcaaagaa ggctatgaga ttttacctgc gaatcaagaa tattacttct
   109981 acaaatgcat cacaaaaaga gtctgctgca tctgtggcaa aacaggagct gacatcgatc
   110041 actttgacaa agcgctagga agacgaaagc gcaaagaagt tgatcatgca gagtacacat
   110101 ttgcagcact ctgcagaatc catcacacag agaagcacaa aataggtgtg attaatttca
   110161 aaaataaata tcaaatcaaa gggatcaaat taaaccagaa aacaatcaaa aagttaaata
   110221 ttggagggta aaaatgacag aacatcgaag ttattatgcg attataccag ccaacgtaag
   110281 gtacgacaaa agacttaaac caaatactaa gttgttatac ggagagataa cggccttgtg
   110341 taatgaaaga ggcttttgtt gggcaggcaa tgagtacttt gcagatttat atggtgtgaa
   110401 taaagagacc atatcgcgat gggtaagtga tttgattaag tttggatact tgaatcggga
   110461 aatcatttac aaagagggta ccaatcaaat aatcaatagg tacctacgaa ttaatcaata
   110521 ccctattgac gaaaaacgca atacccctat tgacgaaaaa gtcaaagata ataatacatc
   110581 tattaataat acatttaata atacaaaaga atatataaga gagttaccgc cttcgaaaaa
   110641 atcgaaggct aagcccgtcc gtcataaata cggagagtat aaaaatgttc ttttgtcaga
   110701 tgagcagatg gagaaactca aaacagaatt ccctaatgat taccaagagc gaatcgaacg
   110761 actgtcagag tattgtgaat catctggtaa gacttataaa aactatttgg caactattcg
   110821 aagttgggca aggaaagaaa aaagtgaacc taagaacgca agcagtggat acaagcgcac
   110881 aggaagacga gagaagcttc ctgaatgggc aatcgaccaa gaagcctatc tcaagaaaaa
   110941 agcgctagaa cgagctaata gacaatcaaa agcaccattc taagaggtgg aaaaatgaag
   111001 atcgattatc tagaactaat taatgaaata gcgaattata aaaagggcga ggaattagac
   111061 gtcctgagag acgtatatga tcaactcgaa gaagctggaa ttgaaggaat taagaatgat
   111121 cgttcgagtt ggagtaagct cagatactat ttcgcacttt atatcgatac aacacaatta
   111181 agaaatttag catataccaa attactattt gttgattgtg ttaaaggctt gcaaaaacat
   111241 cttaatgaac ttgagcaggt gtaatcagat ggacctaaag acatttacag cacagattga
   111301 actaatgcat caagaagctt taagacaaag tgtatcgtac gaagacaagt ggctcaacac
   111361 gttccatggc ggacgtgaga gcgcacttga tcaagtactc aaattactga aaggagaatg
   111421 tcgggatgga taagaaagcg gcaatgcagc gaattatcga attgacttat tcagaagatt
   111481 ggcaaaatga caaagaagct gcttcagaag tgatgaggct tggaagagcg atgtgggcag
   111541 acaagagcaa caagccaaga ccacgaaaaa tcgcaatttg gcacggtgac aaacttctag
   111601 tgatagggac agctgaacag ttagcaagtc tcacaggctt gcacgagaaa atcgtgagga
   111661 aaagagcaag gtgtggctac acagacgcta agaagagaac gtttagatac gtggaggaat
   111721 catcatgaca acagaagaag tgattcaaat gcgtattcga agccttcagc gtgagattga
   111781 cgatctggaa cgaacaaagg cagtgatggt caatgaaacg gcgagaaagg caatcgattt
   111841 gcacatagag aatttaagaa gggaaatcca tcgattggag gaatgagcgt ggataagaaa
   111901 gcagcaatga aaagaattgc tgaattaacc aagtcagaat cttggcaaga agacaaagaa
   111961 atagttgcag aagtccaaaa gctcggtaaa tcaatgtgga ctgaaaagcc caaacggaga
   112021 acgccgagaa aaattgcaat ctggcatgat gaccgaattt tagtaacagg tactgctgaa
   112081 cagttatctg aaattactgg attaagcaaa aacattatct gggatagagc taggagctta
   112141 tggattgatt caaaaggacg acagtttagg tatgtggagg agagataatg gatctcatta
   112201 cacaatacag tgacatcatc ctcaagaaaa tcatgatgaa gattcagaaa gataaaaaat
   112261 caaaagaacg agctgaatta gttaagttag aaatggctga aacaggagca ggagtgcgaa
   112321 gtagcaggca ttggaaagca gcagcaaaca ttgaatttta ttacaacgaa attcaaaaag
   112381 ggttcgatca gatgcgtgag ctggatcggc aaacaaattg gagcaagaaa cttcatcaag
   112441 atcgtttcaa atttgtagag aagtataaag aaatattaga agagtatttg aggaggacag
   112501 caaatgataa aaaaactcgt tcaattcagc atggatttat atgatatcga atcaggagca
   112561 acactatctg tggaatcgga ccatctaatc ataaattttg gtggaaagcg ccagattatt
   112621 ttgtgggtag ttgatgatgt actgtttcca gaaattgttc atgatttcga agaatcaaaa
   112681 gcggttgagt ttgaaatagt gaaaaaagta atggaattga ttgaaaaata cgaggaggac
   112741 agcgaatgat accgaagttt agagcgtggg ataaacgaaa gaacgtaatg agagatgtag
   112801 ccgtcttgca ttttactaaa aacggcaaaa caaactttat tgaatattgg ataaatccta
   112861 ccgaattgaa atcatatcac gtgcgaaaca tcgacctcat gcaatccaca ggaatgaaag
   112921 ataagaatgg tgtggatata tttgaagggg atatagtatt agtcagcgtg cgaaatggct
   112981 tcgattactt agataataaa gtctgtattg tcaaaaattc aatagattat tccggattag
   113041 tttgtgccac tgttgatgaa gacttagagt atcaaatttt taacacagag ctgtttgaag
   113101 aatacacgta cgaagtcacc ggaaatatat acgagaatag cgagttattg gaggaacagc
   113161 gatgaataaa caggaagcaa tcaaaaagtt agaaagtatt aaagcgatag gaaatgatgc
   113221 aatagctgct tgctataacg agagtataaa ttcaggtatt acgttaatga aaaaaataga
   113281 cgaaccgcag aaaccagtta ttccacaact cgtggccggt tggcttgaga aatctacgga
   113341 cccttttaca aaagctgaaa aaatagcgta tttaatcaaa tctaaagatg gtgattcata
   113401 ttatttctgt gattggtttg tacgagatgg catagtgacg caagagcaag gagaagaatt
   113461 actcgcttgg gcaacaagac aatcatatga aacactattg agcctataca acggctacga
   113521 ggttgagaaa gagccgttat gggcaataaa gaatgccgat ggaaactatc ttactaaatg
   113581 tgctttatgg ggaaaagatg gagtaaatta tagttttgaa tgcaatccat ctcatcgatt
   113641 gcttttcact gataaagcaa cagcggatgc tgcagcattg ttggtgaatg gaacagtgga
   113701 agaggtggta gaaagatgaa actaaaagac ggattttacg ctagcagtca cggtatcggc
   113761 ggtttaatgc tagatatgcc gacaaagaac cctaaaacac gcaagaaatc aaaattcaaa
   113821 gtcggtgaca tggtccgctg tgaagcagaa gagttcgttt atccgttcag aggatacgtt
   113881 aaaaagatac tgtcaaactc agcaatcatt cgtattgaaa atacaatgaa gtgtgatcgt
   113941 tcgactgcaa aacacaagca ttatttagct gtagcgagat tagttgacat ggaagtaatc
   114001 aagagcaaat aaaaaaagcc ggatcgctcc gactgattca ataaatccaa cacatttatt
   114061 atatcacata aaggagcggt ttgacttgat gcaattgtta cgagaggtag atttcaaaca
   114121 gacaagatgt aatgcgagag atgtgctgaa gaactttcgg cgtttggagc ggatggcagg
   114181 tcgctctttg atagatatta agtcgccgat tataacggat atgccgaagg caccgaagca
   114241 tggcaataag gcagaagacg cgattattca gatgatggat atagaaacgg agagagatgc
   114301 gattctagcg gctttgatgg ctcttagtct gattagtcgt cagatactct actacagctt
   114361 ctgtgtgcca gatagcttct caaactacag aattagccgt gaagtgggtt attcagaaag
   114421 aagtatacaa cggatgaagt cggaagctct aatagagttt gcagaagcat ataaacacgg
   114481 aaaaataatt gcttataaat aatttggcgg ttttttggcg gaatgatggc ggtttttaga
   114541 catttaccag tgttattatg gtagtgtcga aagattagga aacaggatcg acaaaataaa
   114601 cgaagggagg caatctccct catcgtttta aacttcttct tagatagaca gcaactaatt
   114661 atgaagaaaa ggatgtgaat tcaactcctc ctaaattctt catcggttgc tgtttatttt
   114721 gattagacag cagcactcac aaaactaaac atgttcttgt cgtctttcaa ctgctgctgt
   114781 ctattaattt atgtattgga gggaagaaaa atgaaattat cagtagaagg cactccagaa
   114841 gaaatacaag aattgctcca agctattggt agtagcaagg agcaaaaggt aagtgtttct
   114901 aattcagata ttgacggtat ttgcaattgt ttaaacagag aaaaaatatc taatccttac
   114961 taagagaaaa tatgttcgtt aatgaatttc caattttcct ctgtagctct accttgataa
   115021 tttttttgca gttcacagat gaataaggaa tcgttattat caagtactgt atttaatttt
   115081 tcacacattt gatttggatt caaattagtt ttaactaacc aaaaagattt ttgtagcttt
   115141 atatatgccc caaattcttt tattatttca aatactttat catacttttg ccctgggtta
   115201 ttaagatcat aactaatcat gtagggttta tacatgttgt cttgcacatc cttgttttat
   115261 atttcagcgg accactcgct gataaataaa attatacgct tagtatttat tttcacaata
   115321 ttaatttatc gtaataactt ttgagtaaat agaacaaaaa acctgcacta gtttccgcta
   115381 gtacaggcag tgactatatc ggttgataat ctagcatata ttaaaaataa ttgcaagaaa
   115441 agaaatttat agtggtttat accaaattat caaagcaatg ttattttgtt gctgtctatt
   115501 gttttttaat tattcacacg ataactaaag gtgggtgaag agaaatgatt ccattaataa
   115561 tttcaatttt tgcgctctgt cttaatgtct atatgattgg atttaaaaat gggcaaaata
   115621 aaaaatagta gcagccaaga ataattttat agtgtcactg tggcggaaag ggtagacgct
   115681 aagcatgtgt gctaggtcaa tgcttcggca accatgcaag gttcgattcc ttgccagcga
   115741 cattaaatgc ctatgacggt tacgactacc gaaaaaagat cgttaagaag ctatacggtg
   115801 ctacgtacgg caatgtagta agtgtgctat ctgtacacca ccaagcttcg gtcactgtgg
   115861 cggaagtaga agacgcagcg gtaaatggcg agtagcctcg tgagagcctg gtaagttctc
   115921 gtgagtggtg caatcccact ccagcgactt taagcaaccg aggcatcggc ggtttaaaaa
   115981 tataggggtg cgcaatttcg tacgcgtttt gtgcatcgtg caagttacta ttacatatta
   116041 gatcactctt tgagtggtct ttttattttt gcacaaagga ggaaacaaca atgtatagac
   116101 cacaatactt agaacagaag tatgaagtaa tcactgttca taaaggtaat ggcgaaaaag
   116161 tatatgagta tagaagacca ataaagagcg atacatataa acgaaaggaa aacaatgaag
   116221 ttattccatt gtatggcaaa agaatagcta agcattaaat aagattgcga aaggagacgg
   116281 aacatgaccg aggaattcta tagatggcta ttacagttga caagagaaga tcgtttggtt
   116341 aagttctatc agtctcctaa atggcgcagg cttagagaga aagcgatgaa acgagatcac
   116401 tatgaatgcc aagagtgtag aagactaggt aagtatcata gagtagagaa cgttcatcat
   116461 ataaaggaag tcaaggatag acctgactta gctttagatt tagataatct tatttgttta
   116521 tgtgttgaac atcataatga agttcatggc agatatctta cagcattaga taaacaagag
   116581 aagaagatag aaagctttgc taacttcgat gcaagtgaaa ggtggtaagt gcatgatcat
   116641 caatgataat ggcagagagt atgatacaga aaagattgaa gagtattcat cttatactca
   116701 gggattaatt aaacgtttga tatacgttcg ctatgtaggt attagggatc tgttatcaga
   116761 taactgttgt agtaaataca aagtgaatca agtaagagaa gcgttgaata aagataataa
   116821 cgtcgaaaga ataaaaaatg tttttggata tagtattgaa gagattaatt attacattga
   116881 cttcgctgaa gctttcattc cgatggtgag ataacccccc cttaaaataa atcgcaaatt
   116941 ttttgggggt gatgaaacgg agggggctgt caggaaaaga gattttttcg aactttatca
   117001 tgaaaggagg gctaaaatgt ttaaaaacga attgtctcaa aatcgctaca gagaaaaatt
   117061 acgccgctct ttaataagcc aattggaaag tcagaaaaca aatattgagc cattcttaga
   117121 taatgttgat cgttatatca gtttatggga aacggcgata tcactggaag aagatatatc
   117181 cgagaacggc attagactgg agaatggtaa aaagaatgaa tcagtagcgt tgcttgtttc
   117241 tgtcaacaaa caaatgggat tgatgttgga taaacttgcc attactcctg aattggtagg
   117301 tgaagcaaat gaatcaattc ctgagttata agcatattga aaattggttc aaagctatag
   117361 aagaaggcac tatcaaggta tgcaaagagc aattattgct aaaaaattat ctagaagaaa
   117421 gagtctttac tagagaagat atttacttcg ataagcagat ggtagaggat tcaatcaata
   117481 taccagcaca atactttcca ttcgaattaa ttccgtggga aaaatttcta caatgtttta
   117541 tttatggtgt tcgatggaaa aaagataaaa cactagtgtt caatagatat ctttcattaa
   117601 tgggacgtgg taatggtaaa actggttttg cttcttggaa caacttcttt ctactaaccg
   117661 ctaaacacgg tattaaaaat tatgatattg atatctatgc caataatgaa agccaagcaa
   117721 agactagttt tgatgatgta tttaaagtaa ttaaagatca tcctgattta gataaaaaag
   117781 tatttaaagc tacgaaggaa gttattcaaa atatcgctac aaacagcaaa cttcgttata
   117841 acacggcaaa tgctagaaca aaagatggga agcgaccagg tgcaaaccgc tttgatgaaa
   117901 ttcacgaaaa tgaagattat tcaatgataa atgtggctac ttctggtggt ggtaaaattc
   117961 gagattatag agaattttat gatacaacta atggtcatgt tcgtggtggt ccgcttgatg
   118021 acattataga agaatcaaaa atgattcttt ctggagaact tggaattgac aaggatggag
   118081 cagaattttc tagtttgttt ccatttattt gtcgcttgga taacgataat gaagttgatg
   118141 atcccgacat gtgggaaaaa gcttgtccaa ctattaatta caatgcagat ttaaaacgga
   118201 aaatgtttca agaatactct caaatgcaac gtaatgctgg tttaagactt acgttcatga
   118261 ccaaacgaat gaacagacct atggaagata cacgatttgc tgttgcttca tatgatgatg
   118321 ttctgcatac gaaagaaaaa gaatttcctg aaaaaatgga tgaagtgata ggaacagtcg
   118381 attttgctga tagacgagat tttgccagcg ttgggttgct aggaaaatac gataaagatg
   118441 tttattttac acaacatact tttatccacg aatcagccct tcgattacaa aacatcaaac
   118501 gagaggttat agatatttct atagatcaag gaaaatcaca gatcgttcat ggaaaaaata
   118561 tagaagctga ttatattgta ggttggtttc ttgaaatgag taataaatat tatattaaaa
   118621 aaatcgctat ggatatgtac cgtgcaaaaa tattgaagcc cgctttagaa gaagcaggtt
   118681 ttactgtgga aattgttcga agcggatctg ttacacatgg tatgttaaaa gatctggttg
   118741 atgacctttt tattaatcaa cgtttatttt ttggtgacga tgcgattatg cgttggtatt
   118801 gcatgaatgt atatgaagag catatttcta atggaaatat acgctatgaa aaaatagaac
   118861 ctgaaactag aaaaacggat ggcttttttt cattccttca tggtttgaat tttttagatg
   118921 atatttatga ttctgctcct gtaacagtca caaatagctc agtagaaaat acaggaactg
   118981 gatttactcc tctagtattc taacttgaaa ggaggtgaga aagtggggat ttttcaaaag
   119041 gcggtaggat acttcacaaa aaaagcaacg gttcctttag aagaatactt ttgtaaattg
   119101 caagttgatt ttgtgtatcg aaaatttgcg attgaaactt gtattgattt gattgcaaat
   119161 gcgatgagta aagcggaatt caagtcatat gaagatggaa aaaataaaaa gaatgatctt
   119221 tactataggc tgaatgtagc tcctaataag aaaaataatg caacagaatt tagaaaaaaa
   119281 ctgatcagga gattaatatt ctacaatgaa gtattgatcg tttctccgtc taataattct
   119341 agcgaaatat ttattgcgga tagttgggat gtcacagaat atgcattgaa agatgatgtg
   119401 ttttctcaag tgcaaattaa caacatagtc cttgatagag aatttctaga aagtgatgtt
   119461 atctatataa aatacgcaga tcaacaaatt aggcaactag tcgatgcgta ttatcaagcg
   119521 tatgggaaac tcatttctag tgccatgaat gtttacaagc gctctaacgc tcgtagatac
   119581 gtactgaaag ggaatttatt ccgaccgcaa gacaatacaa cacaagatca aatcaataaa
   119641 atgatgacat cacaatttaa ggcttttatg gaagctgata atgcaggtgc ggtatttcaa
   119701 ttacaaaatg agtacacatt agaagatttc agcggaaact tccaaagcaa ttcaagagat
   119761 ataaaaaact taatagacga catctttgag atgacagcag cagcgtttca cgttccgaaa
   119821 aacctactaa agggagacat gagtgggtta tcggatcaag tggacgcttt tttaatgttc
   119881 gaaatcatac cgattgctga acttattcag gatgcgttta acgctagtct ctatgaagta
   119941 gaagaatact tgtcagggaa ttttgtacgt gtggatacaa ctatgatcaa gattactagc
   120001 ttcaaagatt tggttgacgc tattgatgta ggcattagaa atggagtatt tacaatcaac
   120061 gaaggaagag aacgcgttgg aaatgatcgc tctgataagg cgatggcaga tgaaatattt
   120121 ataactaaaa acaatcaaca agtatcgaaa ggaggtgagg cgaatgacga caatgaaaac
   120181 atttctagca gtaaagaatg aaggcgcagt accgcaaatt tttattcagg gatttattgg
   120241 ttctagttgg ttctttgaag ggaatactga caagggaatc aaaaatattt tggatagtct
   120301 aggtgatcaa gaagaaattg aagtagtaat taattcaaac ggtggagacg tatttcaagg
   120361 gattgctatt gggaacttac ttaagtcaaa taaagcaaaa gttaacgttg tgattaacgg
   120421 cttagccgct agtgctgctt caattatcgc aatggctggc gatactataa aaatctacaa
   120481 caatgcacaa ttgatgattc accgcgcttc cacatacgga gaaggaaatg tcgatgactt
   120541 ccgtacgatt gctgaccaac tggaatcaat tgataaatcg gtaaaggctt catataaaac
   120601 acgattcaat ggcacagatg aagcattgca agaacttctt gaaaaagaat cgtttatgga
   120661 tgcagaaaca gctttgagtt atggattggt cgatgaaatt atcgatgcag aaaatagctc
   120721 aggtactgaa gctaaaaaag aacaaagcgt tgaagaaatt ttgaatgacg ttaaagaaaa
   120781 aagagcagaa aaaattgctg catttacagc agcattaaat aaaacatttg gacaaggaga
   120841 tgtaaaataa tgacagttaa aaatttaaaa ggtgtaacag ctgcaagcga ccaattgatg
   120901 aaagctttta aagatggtaa cgaagaatct tttagcgcag ctatggtaag cttatctaag
   120961 gaaattcagg ataaaatttt agaagaagca acagcaaaaa atcaagatca attagtatta
   121021 atgaaccgtg gtcagcgtgt attaactaca caagaaacaa aattctataa cgaagtagtg
   121081 aaaaacgaag gttttgcagg ggtcgaagaa ttagtgccag ctactgtatt tgaacgtgta
   121141 tttgaagatt tagaacaatc tcatccacta ttgcaaaaaa ttacttttgt taacacaact
   121201 ggtgtaacag aatggattgt gtcacgtgga gtcaatccag catggtgggg taaactttgc
   121261 gaagctgtta aaaaagtttt agataatggc tttgatgtaa ttaacatgaa gcagttcaag
   121321 ctatcaggtt atattcctgt atgtaaggca atgcttgatt taggtccagt atggttagat
   121381 cgttatgtcc gtactgtttt agtagaatca ttgagaattg cattagaaca agcaattgtt
   121441 gatggtactg gtaaagatat gccagtcgga atgatgcgtg acatgagcaa acaaactagc
   121501 ggagaatatg ctgaaaaaaa agcagaacct attacagctt tagatgctgt aactatgggc
   121561 ggtttgatgg cgcgactatc aaaattcaat atcgaaggtg tgaatgatcc gatttatcgt
   121621 aatgtgaatc cttctgatgt ggtcctaatt gtgaatccaa ctgattactg gtctaaagta
   121681 ttcccagcta agactgtact aactgctaat ggagaatacg tacaagtatt gccagtacca
   121741 gtttcagatt tgcagtcaac ggctgtgcca gaaggaaaag cagttattgg ggtagcctca
   121801 gattacttca tgggtgtagg atctacacta aaaattgaag cttcagatga ataccatttt
   121861 gttgaagacg aacgcattta tctagctaaa caatatgcaa acggtcaacc taaacgtaac
   121921 gatagtttca ttgtattaga tattagcgct ttgggaacta ctactacaac tacaaaacca
   121981 acaaccacaa caactacaac acaagcgtag gtgatcagaa tgaagtatat tctttgtcag
   122041 ccggcaatca atcggtttaa atgggagctt gaagtttgtt taactaatct gaagaaacta
   122101 ggaatcaaag atatcgtatt gcttttcagc agacacgatg atcagatacc tatttttttt
   122161 gagaaggaat atggtgttga agttcatgtg tacgatgatc tgcgggacga caaagagtat
   122221 attccttcga ttaaaccata tttatggtgg aaatatttag aagaagatca ttcgcgtgag
   122281 gacgaccgat atttctatat cgattcggat gtcattttca ataaaagaat taatttgcgc
   122341 aaattgcctt ctaaagatga tgtttggtat tgtagcgact gctgtagtta tctaagtctt
   122401 gattatatta gaagctgtga aaacggagaa aatattctaa aagatatggc aaacattgta
   122461 aatgttacag tagaatcttt ggaaactata aacactaatt caggaggcgc acagtgggtt
   122521 attaaccgtc ctaaagcgaa ttattggaaa aaggtttatc tggattctaa tcggctatat
   122581 cgctacctta gagggcaaaa aacaaatata caaatctgga cagccgagat gtgggcacag
   122641 ctttggaaca tgatgtattt caatattggt cctaaagttc acgaggaatt agacttttgt
   122701 tttgctactg atccaataga aaaagttaaa gaagtaaaaa tcttacacaa tgctggagta
   122761 acaacaaacg atgaagattt atttttcaaa gggagatacg tgacttctac gccttttgat
   122821 gaagatttat catttgtaaa caagaaaaaa tgctcttacg catatgttaa agcaattaag
   122881 gcggtggtta gatgacgcct gaacaagtga ctgaagaatt gctaatagct gtgaaggata
   122941 atatttacgt tacctggaac gaagaagatg agtcaattaa aaagatgata gctaaaaatg
   123001 ctgtttatct tcaaagtaaa gtgagtacaa cactttcttt ttctcctgaa agcttagaat
   123061 acggattgct aatcgaaaga tgtagatacg actggaatcg tgctttagat gagtttgaac
   123121 aaaatttcgc tagtgagtta ttaggtttca ttcaacatta tgcgctacaa gaatatattg
   123181 caggtgatgt gaatggcgaa taatcgtaga ctcgaagaaa cattcaacga tggttggtta
   123241 aagattttga cgcaaactac caaaagaaat gaactaggaa aaaagattgg tgtagaagat
   123301 acagaaatca cttctttaaa atttagaaat ctttccatga gagatagtga tataacagct
   123361 atggatgcga tgggatcgaa attaactaag aaagtaaaga ctccatttca tccaatcgcc
   123421 aagaaattta ataaagatca atattttatc gtaatcgata gtatgcgtta caacgttatc
   123481 tatgccgatt acgataattt ttatatctat ttttatcttg aaagtgtggg tgaatatggt
   123541 gattgataat tctaaagaaa aagaacgttt aaataagcaa atttctgcta tcaaaacttc
   123601 cttagaagag cattttggcc tcaaactctt tcaagactcc gtaggcgagg atgagctacc
   123661 tgatgatttt aattacttca ttctcgaaac aggagaaata gaaatgatca ctgagccaaa
   123721 atatagcgtg ggtcaaaatc tatatctaac tttctattca gaaaatagag aagatttaac
   123781 aggagactca ctagatatta tttcattgat tcaaaatcgt tcgattcgtt ttcagagaat
   123841 ggatcccaat catttaaaac tagagaacca agatcgctat atcgatcaat tggtatttac
   123901 gtttagacga ttattgaaga gtgattgtca tggctaaaaa tagttgggag ctaaaaataa
   123961 atggacatga tgaacttctt gtgcggatgg aacgctattc aagcgagagc gaacgactga
   124021 ttaacgaagc attgaaatca aaaggttcgg ctattgcagt ggataggatt acagaaaaaa
   124081 ttcctgtttc tgaagcagat ttaagaagag ggcaccaaca cgcaaaaaat agtcgtccac
   124141 ttaagactca atacattaat ttgggtttca tcattagacc tacaagaaaa tttgagtatt
   124201 taaaatatcc tgatttgggg ataggtactt ctaaaagaaa tcagccggac gaatttatga
   124261 gaagaggatt aggtcttgca cttgatccaa ttacagaact tctgattcgt caattcgata
   124321 aattaaataa atagggggaa caacaatggc taaaacaaaa actgtagtaa caacgttcga
   124381 taacgtaagt atcaaacgaa ttgcttttaa ttttaagaac gcaggaaatg caatcgcaac
   124441 gaattgtaat ggacaattag atggcgaaac agaaatgcaa acggtggtta aaaaatgtgg
   124501 agcgacagaa gtaaaatcaa aatctaaacc aatcaatatg acggtaacaa ttactgcaca
   124561 tgtaccgatg gaagtttatc gacgtttcaa tgggttgaaa caagatggac gtattaaacc
   124621 aggcatttac tcttacggtc ctgattccgt aggcgaagat ttctcacttg ctgcagagat
   124681 cgtggatgac ttcgaagaaa atagaaagtt agttggtatg ttagcatgca cttcgaatac
   124741 aggattaaca ttctctattg aaaatggtgc ggatgaagta gctgcgttag aactagaaac
   124801 aaaagttatg caagatgaat ttggtaaatt ttatcatgaa gcaattgttg cagaacttga
   124861 agaagactta acagatcaat ggatgacgaa tctatctgct gatgtgatta aaaaaacttc
   124921 agttgtgaca actacggcca ctcaatcaca gtaaaaaaaa cggaggtagc gaaatgaacg
   124981 aagattactc aaaaattgaa ctaaacgatg gaacaatttt gaatttagaa cctaaactga
   125041 atatcaagaa attattgatg atcaatagag attttaacac agacgagttt gcaaaaatga
   125101 ctgtgggaaa aggatccatg gatatttctg ttattcaagg tgcaaaggct gtgtatattg
   125161 cttaccgcca agcgaacatg actgattata tttcattcga tgaatttatc gataaatggg
   125221 attttgatat ggctactgcc agctatattt atcaattgat gatgttcaaa caagcacgcg
   125281 atgcttatca aaaagaattt gaaaaagcaa ataaggaaaa aaagcttcaa aagtaaaaat
   125341 tccaaagctc ttagttgaaa cgtgggtcga tgtctattcg atgttgaccg acgttttttc
   125401 tatgccttca gatttggttt taagcgatat ctgtttagat gacattttgc aaatggctta
   125461 caacaagagt gcttatgaag gatggaaaaa ctatgcaata aaccaatccc agaaaaacta
   125521 aagaaaggag gtaaaaaatg gctaaaaaga gaacagaagc agaagtaact ttcatagcta
   125581 acgatgacgg attgaaatct acgttaaaag aaatcagtgc tgaattaact aaaaatagag
   125641 cagaattaaa actagaacaa gctcaattac aacagactgg ttctgaatca gacaagttag
   125701 gaagtaaatt atcttcttta gaaaagcagt atgaattaca aagtcaaaaa gttgaagtaa
   125761 ctagccaacg tttagccaat gcgaaaaaat attatggaga aaattccacc gaagttcaga
   125821 aacttgaaag agaactgatt aatcaacaaa cagcgcaaca acgtttgtca aacgaaattg
   125881 ataaaacgag taatgcacta gctcaagcaa aaggcgaaat acagacgtac gagtctacaa
   125941 tgcaacagtt ggatagcgaa caaaaaaatg ttcaagctag tgcttctctg attgaatccg
   126001 aatacaaaaa atggcaagca actgctggtc aatcagcttc tgaagccgag aaattagcga
   126061 aagcccaaga atatgtttct caacaatctg aaaatgcgga gaaaacgata gatatcctaa
   126121 gacgacagtt agaagctaca cagtctgaat ttggcgctac atccacagaa gcaatgcaga
   126181 tggaagcgaa gcttaatgat gctgaacgtg aatttgaaga gttaggacaa gctgctaaaa
   126241 atgtagatac aactaacttg gacgatatcg gaagcaaaat agatatgaat aatttaatgg
   126301 aagcttctga cgttttaagc gacattggcg ataagcttac agaattaggg aaacaagcag
   126361 tggactctgc taacagtgta ggtagttccc agagtaagat acaagctaat tttggtttgt
   126421 ctaaacaaga ggctgaagaa ttaacgaatg tagccagaga catttattat aaaggttttg
   126481 gagaatcgtt agatcagtcc acagatgcat tgattttggt aaagcgtaat ttaggagatt
   126541 taaataatca agatttacaa aatatcacgg aacaagctat ggtcctagaa aacaccatgg
   126601 gcgctgatat ggatgaaacg ttacgtggtg taaatggctt aatggtcaat ttcggcttga
   126661 gtgctcaaga tgcaatggat ttaatggttt cgggtactca aaacggttta gataaaacgc
   126721 acgaattagg cgacaatatg gcagaatata gccaattatg gagtcaaatg ggatattcag
   126781 ctgatgaaac gttcggaatg cttcaaaatg gtttagatgc gggtgcttat aaccttgata
   126841 aagtcaatga cttagttaag gaaatgggaa tatcgttaac agatggtcga tttgagcaaa
   126901 acatggatat gtttagtgaa agtactagaa aagcttttga agagtggaaa aatggcggag
   126961 gaacacaaaa agacgttatt aattccatga ttcaagattt tagcaatatg gatggtcaat
   127021 acgaccaatt aaataaagct tcgacaattt ggtctgcgct tggcgaagat aatgcgatga
   127081 aagttgtcca atctttaact gatgttaacc atacatttga tgatgttagt ggatctgcac
   127141 aaaaaatgaa tgaagattct actactccgt tgcaagagtt gaacgggaaa atagctgaat
   127201 taaaggattc attagctcct ataggcaaca caatcataga tgcactcgaa ccagtaattg
   127261 attttctagg aaagatggct gatgcgttta ataatcttcc acaaccagta caggatttca
   127321 ttgttgctat aggtggtctt acagcagcat ttggcatact gttaccggca atactagccg
   127381 tgtcatattt atttggtccg atgatgctta taattggagg aattatagct gttatagcag
   127441 gcgttattgt ggcaattaag aactggggtg caattactga ctggtttagt ggtttatgga
   127501 aaaaatttac tgattggttg ggtgatactt gggaaagtat aaaagacgga gcctcatcag
   127561 tttgggatgg ggttaaagaa acctggtctg gatttgtaga ttgggttcaa gatatttggc
   127621 aaggagtttc tgattggttt ggagagctat ggagcggatt agttgaagga gcttccaaca
   127681 tctggcaagg agtccaagaa acttggcaaa cattcgttga ttgggtttca aatatttgga
   127741 acggagtcaa agaagtatgg tcgattattt gggcagacat tgtaggaatt gttcaaatac
   127801 catggacatt aataacgtca ttgattcaag ctggtattaa tattatcgtg ggtatttttg
   127861 atgtagctgg acagttattg ggcgcagctt ggcaagctgt ttggacacct atttctgatt
   127921 tccttaaaaa tacttgggat actatgacac aatggataag tatcgcttgg aatgggattg
   127981 taactacatt ccatactata tttgatccag tagtggcatg gtggaatggt atatggacag
   128041 ctattagtac tacggcttca aatatttgga attcaattag tgcaacagct tctagtattt
   128101 ggaacagtat caagaataca atcactagct tggtacaagc agctgctaca gtaattcaaa
   128161 atatttggtc aactgtatct agttggttag gtggaatttg gaattcaatc agctctacag
   128221 catcaaatat ctggaatagt gtgactagta gtataagcaa tgctataaac gcagctaaaa
   128281 gtgccattca aagtgtttgg aatagtatat cttcgtggat tagcggaatt tggaacggta
   128341 tcaaaaatac tgctttgaat ctttggaatg gaattacaag cactattagc tctaaagtaa
   128401 acgatggaaa aaatgcaatt tcaagcggtt ggtccaatct aacaggtatt gtttccgaca
   128461 tattcaataa tgttaaaagt acaattgcta acatatggga aggcatcaaa aagactgtta
   128521 gcgctccaat tgattggatt agagacaaaa tcagtggcat ttttgataat ttgaatattt
   128581 ctataccaca tattccgtta ccggaattta tcatggaagg cagctttaac ccgctaaaag
   128641 gtcaaatccc ccatttgcgt gtaaaatggc atgctaaagg aggtatcttt actaaaccaa
   128701 ctttactagg tggaatgaac ggtgtcggtg aagcaggacc tgaagcagtt ttacctttga
   128761 aaagatctgt tttgcaagaa attggtgatc gtatcttgag tagcacatca gtttcatcta
   128821 gggcacaaac gattcaacct gtgaataact acgaattcaa tttcacaatt gatggtaacg
   128881 cagatgaggt tactatgaag caaacaactc aacaaatcat tgatagcatt acaaaaattc
   128941 aaaatgataa tgcttcggca tggcgttaaa caggagagta tttctcctgt ttttttagta
   129001 ttaaaaagga tgtgaaaaaa tgactgattg tatacattct ataatcgatg gatttcctga
   129061 ttatttgcat aaattggctt tagctgaaag accaaccata ccttctccaa aaagacagag
   129121 agttgaaact tctgttttag gtaggttagg tggcttagta caagattact cgtttgaaga
   129181 tatgtcgttt acattgcact ataactattt agaggatgtg gaagaccatc aagcgttcaa
   129241 gcaatcgttt tatatcatgc gtcattggtt aaactatgca aagaaattag aattctctga
   129301 cgatcccaac gtctattacg ttatccagac tatcgatatt ggggatgcag aaaacgatat
   129361 tgttgaatgg ggagagttcg atgtaaatat tactgcgaaa ccattcgcaa gagttcaaga
   129421 agatgtacct ataaccgtag ataaaccaca gtcatttaac ttgctgaata atagtttaga
   129481 agaaagtttt ccaaagatta tcatcactcc ttcagctact tcatgccagt tcatcttaaa
   129541 tgattatgtg tttagtttcg aaggcttagt agcaggaact gatgtagtca ttgatagtga
   129601 tttgatgctt tgctacgaag agcaatcgga cggagatatt ttagatcggt ccaacaaaat
   129661 gaagaccatg caatatccga cattgcaagt ggatatcaat cattttaatt gcactggttt
   129721 gagcaaaata caaatttatc gtaacgggtt aaggtaggtg aaatagatga tcgataattt
   129781 aataactatt tacgataaaa atgacgcgaa taatttagct gaacatttat atgatacgca
   129841 aggtttaggc gctttgtcag actggttaac agctactgtt agcaataaac taaacggagc
   129901 cgagatattt cagggtactt attcaataaa cggaactaat gcagatttga ttgtagacgg
   129961 acgtattatt cagtgttatg tagatgaaaa tcgagcaaaa cagcgtctac ggatttatta
   130021 tgcaaaaact tctgtaatag gcaatacgat agaagtaaaa gctgaaccta ttttcaatga
   130081 tataagaaaa tcggtgttga ataaatatga cagcggaaca gaaaagatca ctgctactca
   130141 ggcatggcaa aacgcaaaag ttttagcgaa accagctatc ccttcgcagt tttctttctc
   130201 gtcattagta gatacgcttg ctaatgtgaa gatagaaaag gcgaattttt tagaattctt
   130261 tggtggaaaa gagggatcta ttctagatcg atttcatggt gagtttctaa aagataataa
   130321 cacattacgt catgaaaaaa gtctaggtac ggatcataaa atcaaagcga tttatactaa
   130381 aaacttaact ggtcttgact tagagattga tgctcaaagt gttttagttg gagtttatcc
   130441 attcattagc agctcttcag aaggagaaga cgagatcact ctaccagaag aagttatttt
   130501 cacggattac gtggatgatt atcctgctgg atatgtttct tttgttgatt ttaaagacaa
   130561 agcgactgat gtagccacat taagggaagc tgctaaagac tggttgaaaa caaacataga
   130621 taaacaaaaa ccacaagtga gtggttcgat tgaattagta ccattgaggc atcaaagagg
   130681 ctatgaaaaa tttgttgatc tagaaaaagt ttcgatgggt gacggagtag atgtgtatca
   130741 tccacagtta aaagtgaata tgtcagcgag aattgtggaa tatacgttta atgttctaac
   130801 caattcatac gataaattag ttgtaggaaa cgtcaaaaca aacttcttag aaaacacaga
   130861 gaataatgtc agcaatttga ttaatgatgc cattgatcaa ttgaaaaacg gtggcgaaat
   130921 cagtgattta ctcaatgata ttgtagatca tcaaactgat atgattactg gtcaaaatgg
   130981 tggttatgtt ttattagatc ctaaagaagc gcctagtcgt attttgatta tggacacacc
   131041 agataagaat accgcaagga atgttttaca aatcaacaat gctggtattg gtttttctaa
   131101 aactggcatt aatggaacat atgaaacggc atggacgtta gatggcggat tcaatgcctc
   131161 gtttattacg gctggtgaaa tagtaggaat tactattaga ggtactacat taattagtga
   131221 tggtgctgat tatagaacaa gtattgctaa tggcaaaatg acttggtact caaaaaaagt
   131281 taacaaagat attatggagc tagaagcacg tgattatgta agtgctgatg ccggtattgt
   131341 atcatacacc atgaaaactg gtggtggttt catgattaga aatccacagg gtaacttggt
   131401 ttttagtacg tgggataatg gtaataacag accgtttcta tcttttggtg cgcccaattt
   131461 caggtatagc aatgctagtt atgtaacttc tggcgacggt agttctttaa gcattaatgg
   131521 tagtgcgggt aactcatggg aatttaaggt agctggtagg actatgaaat ttactagtga
   131581 tggtatgcta acgttaccag gttgtttttt tggttcatgg gaagatggga aacttgctag
   131641 gtttgaacaa tcaacggtac aagtatataa agattttact gttagaggta ctaaaaactc
   131701 aactgtacca acagaacatt atggacaacg actattgaac gcttatgaaa ctccagaata
   131761 ttatttcgct gattatgggg aagccgttac aggtgacaat ggtaaagttc gtgttgatat
   131821 tgaccccatg tttgctgaaa cagtaaatct aagtcggtat atgacacatg tgacacctac
   131881 agaactagtt ttgtgtgctg ttactcatga agatattgac catttcatca ttgaaactag
   131941 taagccaaac gtattagtta gatggaattt agtggcacac cgtctagggt atgaagatat
   132001 tagattaaaa gaggatacag catatgatag cacagtgctt gaccaaaaac gtttttaaaa
   132061 cgaagacaag gaggtatata aatggctagc agtttatata atttggcttt agatttcagc
   132121 aaagaattaa actacaccaa agctattatg gctcgtcaag gtgataaagg gattacggtg
   132181 acggttaaac cgtttctaaa tggcttgcag atggatacga gtggcggaac atttacttta
   132241 aaaggaacaa caccatctaa ccgttacgta gataatgttg caactagtgt aactagtgaa
   132301 gaagtcacgt tttctcttga tggcacattt atgagtgaag caggatatta taaacactgc
   132361 tacgtagaat atagaaaaga caatcaaatt ttaacaacgc aagatatcat ttttttctca
   132421 ctaggagtgt ctgacatttc gcaaggccaa gccgatgaat atgtttcgca attagaagag
   132481 ttgattcgaa agtacaacga aacttttgat gcttttatgg ctgaaatcaa aggtagagtg
   132541 gatagcttaa atcaacagat tactgattta actggtcaag ctaaaacgct acaagacaag
   132601 ttagatgctc tgaaagaaga aatttctaag ttaggtaact tacaagtgat gtacagtaac
   132661 agcatcgact tcggggacta tgattattcg gagaacccga atttaatgcc atatattaca
   132721 gaaccttggg ttggaccttt gttaggtaat ggacatacag ttaaagatag tgttaaaagg
   132781 gttataactc atactaaaac tagaacagct aattccggcg acatattatc gcttggctta
   132841 ggtattccgt gtacagcgga agctaataat aggtatctta taaccacttt acgaccatct
   132901 acgacataca cattaagcgt tactatgagt gtcggttcag attggactgg agagaccaat
   132961 actatagggg ttaggcttag atatttaaat gaacaaggtg gtatagaact gcccattaat
   133021 gcattaatac cagcaaatgt agaacgcgat aaaatggtca ctcatacatt tactggtata
   133081 acaaaagata atgtaactag cataacaaac tgttatgttg aaatattctc acttaatagt
   133141 gaatataaag gaacggttag tgtcagctat gacgttaagt taaaagcaca ctaccctaac
   133201 ttactagatg gcccttactg gttaggtaaa gttcctttag gcgagaatat tgctgaccct
   133261 acagttgtct ttccacacaa aactagtgaa tatatggttt atggtagacg caatacagaa
   133321 aactatatcg ctgaccaaac atataccata tcaatgaaag caactaaact aacagttcaa
   133381 tcgtttgccg tgtatattgc tgctggccgc gttaaagtag gagacatgaa gcctactgag
   133441 gggttagcta atacatggga gttaactttt actgtaacta agcaacatat agatagtggg
   133501 gtaactaatt atctggaaat ataccaatac ccgtcagcta caaaaggagc tgttcaaatt
   133561 gagtggctca aactagaaaa aggcaatact cgaaccccga atattagtga gtataaatat
   133621 cgtggtactg gtatgcgtga ttcaaacaat ccaaaagatt atgtttggga tctagcacca
   133681 gaatatgtcg aagataattt ggccacagat attaaaattt ctgaaattac tggtaaagca
   133741 aacaattata ccgatgggaa agtatcggag attaattcgc agttgactgc ttcaattaat
   133801 gaagtagaca ccacagctaa ggatgctcaa acaaaagcga atgctaatgc gactgctata
   133861 gatgaattag acaataagat cgatgaacgc attaatgata cagctactac cacattaaca
   133921 gttacaaacg ggaataccgg atcagcaaag ctttatcgtg aaggaaaaac agtttctata
   133981 tattttgtgg ctttaaacgg aaaaagcagt ggtggaaatg attcaacgat actaacaatt
   134041 ccagaaggct atcggccacc aattagtttt gagcaactgg ttggctcgat agaccgttct
   134101 actttgaaca gtgctcagtt atctattggt gcagatggag ccattaaatg gcgaagaaac
   134161 tcaagttatg gatcggatta tacctttgca attacttaca cgatttagaa aagcgtgaat
   134221 cgatatgaag gcagcatata gaccaattga accttacgga ttcgagcaaa tcattgtgaa
   134281 tgatgaagaa catttaccgg aagaatgcac agaagtcgaa ccaccgattc caaattggaa
   134341 accgaaattc aattactggg agggaaataa atgaaaaaca tttggaaata tggacgtact
   134401 ggcggagagt acgcaggaaa agtattggac gacatgcttg tatccgttcc ttacacagat
   134461 cagccaccgc ttgaaggaat tcgtgctgat ggcgaaccgt taacaatcgc tgatcaaatg
   134521 tttgatccta aattgaatca atggattatt ttagcgaacg cactagatca caacgattta
   134581 aacaatctca aagcaatgta tgagtcgtta gaaaatgaga acggcgattt aaaacagatc
   134641 aatgccaaac tcatgctaag cgatgtagca attaaacagg aaaatactgc attgaaagaa
   134701 aaagcggata gtttagcaca aatcaattca aaaatgatgc ttgcttcgtt acaaaatagc
   134761 aaagacattt cagaaattaa agagcaacta aatccagctt caaagggagg tgagtagtat
   134821 gtttagtttt agcgatgtga aaatgatgta tgattggggc tgtttcacta acgaacaagt
   134881 aatggttttc gttccgttgt gcattactga agaaaaagca gataaaatca ttagcaaaga
   134941 agagagcgca tcttaattga tgtgcttttt attttgattc aaggagttgt cacatgatta
   135001 atttagggga atggggagcg atagcaggat caataaccgc tatcgtttct ttgattttat
   135061 tagtaataaa accaattact gcatctttct cgaagattac tgagactctt tcaaaagtaa
   135121 gtcacaattt agatttgctg actaaagatt tagaatcgag caaatcagat cgattgatga
   135181 ttcatgaaga actaaagaaa cacgatgaaa gattagatac acatgcagaa aaattggtag
   135241 aacacacgca acaaattaaa actttattta gggagagaag aaaatgaata ataaaacgtt
   135301 cgaagtacta aaatggttcg cactggtaat tattcccgca ctagctactt tcgtggggtt
   135361 agttggtaaa gcgctcaatt ggcagtacac agatatctgt gttgtcatca ttactggttt
   135421 tggcgcgttt ttagggagtg tgttgggtgt atcaaatcga acctacaaaa tgttctcggc
   135481 tgaaagcgaa gaaggaggaa acaaatgaaa aagaaaatta ctattactgc gatgagcctg
   135541 ttaacggctc tttttttatt acccattaat acgtttgctt atactattaa tgacgagtat
   135601 aatttagcgc cgaatcaagg agactccaga ttagcaattc ctaacaaaat tattttgcac
   135661 gaaactggaa tagatgcacc agcaagaaac gtagccgcca acatgaaaaa taattataac
   135721 ggaagcaatt cttatactac agatgttatt ggtgacggtg ggattgttta ccgtgtgggt
   135781 gagcaaggat atgtttcgtg gggagctggt aacgctaatc cttatgcgcc tgtacagatt
   135841 gaattacagc gcacatatga taaagcattg tttgaaaaaa actatcgagc ttatattgaa
   135901 tatacaagag atagtgcaaa aaaatatgga attccattga ctcttgatca aggaacttct
   135961 ttatttacaa aaggaatcat ttctcatttg tgggtgacaa attatgtttg ggggaaccac
   136021 acagatccat atggttactt atcgcaaatg ggagttagca aagaaaagct tgcttatgat
   136081 ttagctcatg gatttaccga tgaaaatcca acaacttctg aaaacaagcc tgtcattgat
   136141 ccaacacgag ctggtgcagc taatcctacg ctgacagatg gaacaaatca cgcccacatt
   136201 gatcagtttg gggaaatcga aaacgcaaac ttgcatgtgg ctggatggca cattgctaac
   136261 tataaatacg agtatatttt cattatggac tacaatactg ggaaagaatt agctcgagta
   136321 agagctgatg gaatttatag accagatgta aaccaagctt ataatacttc tggaaatgtt
   136381 ggttatcatg tatctttcaa tatgcgtaat tttcctagta agaaagtcta tgtaatgatg
   136441 cgggcaacga atgatccaga gggaaacact aaaggcggtg cgcaagattt ccatgacaaa
   136501 cgttggtatt taaatattcc taaacgataa aaatagctcc tcgttgagga gcagtacata
   136561 actatattga caactataaa aattattcga taaaatagtg atgttatcgc atatcttcac
   136621 tatcacccat aaatagtcac actccaagct atgcgataac aggtttgttg ccacacattc
   136681 tactggttga ttgtttatgg ctttatgtgg caacaaccag tacccttagc tcagttggtc
   136741 agagcagacg gctcataacc gtccggtcgt aggttcgagt cctacagggt acattaacgt
   136801 agccatttga atcgttctgt gttagaattt ttttgaagag tattatacaa gctaaagctt
   136861 ttcttcattg ccactcaaat gagtggcttt tttatgtatc cttttatgga ttaatgaaag
   136921 gatgtttcac atagttatac ttctgtatat ttgaaaagtt ttactttgat ttttaaatag
   136981 aaagacattt gggttaaatt gtgagataat aataaagaag agtttaaagc gcaccccaaa
   137041 ccacttcccc ataagtgtgt tacgctttaa actcttttat atttgaagcc attaaaaagc
   137101 ataccatatt tttgaaaaaa agtgagaaaa aaggcttaca attggagtgg tagttaatta
   137161 gtgacttatt tttgatttta tagcactgat actataaaat atagatatca tcatattaca
   137221 caatcttaat actaacttaa aaaatatctc ctttcacaag tatggtgata aaattcgttc
   137281 cgggctacct ttttaggtag cctactttaa tctttatacc tttctggatc aacgaaagta
   137341 tactttatat agtcataacg ccgatgatcg ctacgtgcgt ccggcacgtc agtc
//
LOCUS       DAFELK010000003        96671 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFELK010000003
VERSION     DAFELK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 96671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96671
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.003"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            123..1247
                     /locus_tag="LP433_000293"
     CDS             123..1247
                     /locus_tag="LP433_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2004489.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            1474..2391
                     /locus_tag="LP433_000294"
     CDS             1474..2391
                     /locus_tag="LP433_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2004490.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            2384..3217
                     /locus_tag="LP433_000295"
     CDS             2384..3217
                     /locus_tag="LP433_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2004491.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            3300..4418
                     /locus_tag="LP433_000296"
     CDS             3300..4418
                     /locus_tag="LP433_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL2004492.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            4412..6310
                     /locus_tag="LP433_000297"
     CDS             4412..6310
                     /locus_tag="LP433_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBL2004493.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            6304..7527
                     /locus_tag="LP433_000298"
     CDS             6304..7527
                     /locus_tag="LP433_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL2004494.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(7613..9547)
                     /locus_tag="LP433_000299"
     CDS             complement(7613..9547)
                     /locus_tag="LP433_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2004495.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            9773..10429
                     /locus_tag="LP433_000300"
     CDS             9773..10429
                     /locus_tag="LP433_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL2004496.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(10503..10856)
                     /locus_tag="LP433_000301"
     CDS             complement(10503..10856)
                     /locus_tag="LP433_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL2004497.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            11048..11977
                     /locus_tag="LP433_000302"
     CDS             11048..11977
                     /locus_tag="LP433_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBL2004498.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            11988..12824
                     /locus_tag="LP433_000303"
     CDS             11988..12824
                     /locus_tag="LP433_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBL2004499.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            13072..13848
                     /locus_tag="LP433_000304"
     CDS             13072..13848
                     /locus_tag="LP433_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2004500.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            14024..14767
                     /locus_tag="LP433_000305"
     CDS             14024..14767
                     /locus_tag="LP433_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004501.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            14760..16340
                     /locus_tag="LP433_000306"
     CDS             14760..16340
                     /locus_tag="LP433_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBL2004502.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(16591..17070)
                     /locus_tag="LP433_000307"
     CDS             complement(16591..17070)
                     /locus_tag="LP433_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL2004503.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(17086..17838)
                     /locus_tag="LP433_000308"
     CDS             complement(17086..17838)
                     /locus_tag="LP433_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL2004504.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            17955..18025
                     /locus_tag="LP433_000309"
     tRNA            17955..18025
                     /locus_tag="LP433_000309"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17987..17989,aa:Gly,seq:ccc)
     gene            18386..19111
                     /locus_tag="LP433_000310"
     CDS             18386..19111
                     /locus_tag="LP433_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBL2004505.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            19366..19632
                     /locus_tag="LP433_000311"
     CDS             19366..19632
                     /locus_tag="LP433_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBL2004506.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            19629..20060
                     /gene="ruvX"
                     /locus_tag="LP433_000312"
     CDS             19629..20060
                     /gene="ruvX"
                     /locus_tag="LP433_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBL2004507.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            20085..20390
                     /locus_tag="LP433_000313"
     CDS             20085..20390
                     /locus_tag="LP433_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBL2004508.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(20471..21616)
                     /locus_tag="LP433_000314"
     CDS             complement(20471..21616)
                     /locus_tag="LP433_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2004509.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(21677..22324)
                     /locus_tag="LP433_000315"
     CDS             complement(21677..22324)
                     /locus_tag="LP433_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2004510.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            22518..22811
                     /locus_tag="LP433_000316"
     CDS             22518..22811
                     /locus_tag="LP433_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004511.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            22855..23166
                     /locus_tag="LP433_000317"
     CDS             22855..23166
                     /locus_tag="LP433_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004512.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            23163..23787
                     /locus_tag="LP433_000318"
                     /pseudo
     CDS             23163..23787
                     /locus_tag="LP433_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            23928..24086
                     /locus_tag="LP433_000319"
     CDS             23928..24086
                     /locus_tag="LP433_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004513.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            24087..24449
                     /locus_tag="LP433_000320"
     CDS             24087..24449
                     /locus_tag="LP433_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004514.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            24486..25334
                     /locus_tag="LP433_000321"
     CDS             24486..25334
                     /locus_tag="LP433_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBL2004515.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            25324..26799
                     /locus_tag="LP433_000322"
     CDS             25324..26799
                     /locus_tag="LP433_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBL2004516.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            27065..27472
                     /locus_tag="LP433_000323"
     CDS             27065..27472
                     /locus_tag="LP433_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBL2004517.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            27475..27690
                     /locus_tag="LP433_000324"
     CDS             27475..27690
                     /locus_tag="LP433_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004518.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            27694..28074
                     /locus_tag="LP433_000325"
     CDS             27694..28074
                     /locus_tag="LP433_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL2004519.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            28208..28363
                     /locus_tag="LP433_000326"
     CDS             28208..28363
                     /locus_tag="LP433_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBL2004520.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            28432..28905
                     /locus_tag="LP433_000327"
     CDS             28432..28905
                     /locus_tag="LP433_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBL2004521.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            28902..30596
                     /locus_tag="LP433_000328"
     CDS             28902..30596
                     /locus_tag="LP433_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL2004522.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            30562..30747
                     /locus_tag="LP433_000329"
     CDS             30562..30747
                     /locus_tag="LP433_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004523.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            30751..31926
                     /locus_tag="LP433_000330"
     CDS             30751..31926
                     /locus_tag="LP433_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL2004524.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            31919..33442
                     /locus_tag="LP433_000331"
     CDS             31919..33442
                     /locus_tag="LP433_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL2004525.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            33498..33782
                     /locus_tag="LP433_000332"
     CDS             33498..33782
                     /locus_tag="LP433_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL2004526.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            33769..34104
                     /locus_tag="LP433_000333"
     CDS             33769..34104
                     /locus_tag="LP433_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL2004527.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            34399..35025
                     /locus_tag="LP433_000334"
     CDS             34399..35025
                     /locus_tag="LP433_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004528.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            35767..36603
                     /locus_tag="LP433_000335"
     CDS             35767..36603
                     /locus_tag="LP433_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBL2004529.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            36668..37102
                     /locus_tag="LP433_000336"
     CDS             36668..37102
                     /locus_tag="LP433_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2004530.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(37170..38492)
                     /locus_tag="LP433_000337"
     CDS             complement(37170..38492)
                     /locus_tag="LP433_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBL2004531.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(38646..40286)
                     /locus_tag="LP433_000338"
     CDS             complement(38646..40286)
                     /locus_tag="LP433_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBL2004532.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            40616..41086
                     /locus_tag="LP433_000339"
     CDS             40616..41086
                     /locus_tag="LP433_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBL2004533.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            41715..42818
                     /locus_tag="LP433_000340"
     CDS             41715..42818
                     /locus_tag="LP433_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL2004534.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            43102..43782
                     /locus_tag="LP433_000341"
     CDS             43102..43782
                     /locus_tag="LP433_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL2004535.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            43872..44906
                     /locus_tag="LP433_000342"
     CDS             43872..44906
                     /locus_tag="LP433_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL2004536.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            44920..45255
                     /locus_tag="LP433_000343"
     CDS             44920..45255
                     /locus_tag="LP433_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004537.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            45239..47719
                     /locus_tag="LP433_000344"
     CDS             45239..47719
                     /locus_tag="LP433_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004538.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            47775..49334
                     /locus_tag="LP433_000345"
     CDS             47775..49334
                     /locus_tag="LP433_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004539.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            49331..50695
                     /locus_tag="LP433_000346"
     CDS             49331..50695
                     /locus_tag="LP433_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2004540.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLTRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            50866..51936
                     /locus_tag="LP433_000347"
     CDS             50866..51936
                     /locus_tag="LP433_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004541.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            51951..52619
                     /locus_tag="LP433_000348"
     CDS             51951..52619
                     /locus_tag="LP433_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004542.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            52639..53217
                     /locus_tag="LP433_000349"
     CDS             52639..53217
                     /locus_tag="LP433_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2004543.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            53620..54531
                     /locus_tag="LP433_000350"
     CDS             53620..54531
                     /locus_tag="LP433_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL2004544.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(54787..55704)
                     /locus_tag="LP433_000351"
     CDS             complement(54787..55704)
                     /locus_tag="LP433_000351"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBL2004545.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            55906..56343
                     /gene="zapA"
                     /locus_tag="LP433_000352"
     CDS             55906..56343
                     /gene="zapA"
                     /locus_tag="LP433_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBL2004546.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            56401..56949
                     /locus_tag="LP433_000353"
     CDS             56401..56949
                     /locus_tag="LP433_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBL2004547.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            57064..59424
                     /locus_tag="LP433_000354"
     CDS             57064..59424
                     /locus_tag="LP433_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBL2004548.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            59511..59825
                     /gene="trxA"
                     /locus_tag="LP433_000355"
     CDS             59511..59825
                     /gene="trxA"
                     /locus_tag="LP433_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBL2004549.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            60007..61785
                     /gene="uvrC"
                     /locus_tag="LP433_000356"
     CDS             60007..61785
                     /gene="uvrC"
                     /locus_tag="LP433_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBL2004550.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            61930..62829
                     /locus_tag="LP433_000357"
     CDS             61930..62829
                     /locus_tag="LP433_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004551.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            62822..64084
                     /locus_tag="LP433_000358"
     CDS             62822..64084
                     /locus_tag="LP433_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004552.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            64247..66145
                     /locus_tag="LP433_000359"
     CDS             64247..66145
                     /locus_tag="LP433_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBL2004553.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(66444..67163)
                     /locus_tag="LP433_000360"
     CDS             complement(66444..67163)
                     /locus_tag="LP433_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBL2004554.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            67500..67832
                     /locus_tag="LP433_000361"
     CDS             67500..67832
                     /locus_tag="LP433_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004555.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            67819..69822
                     /locus_tag="LP433_000362"
     CDS             67819..69822
                     /locus_tag="LP433_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBL2004556.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            69841..70311
                     /locus_tag="LP433_000363"
     CDS             69841..70311
                     /locus_tag="LP433_000363"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBL2004557.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            70332..70916
                     /locus_tag="LP433_000364"
     CDS             70332..70916
                     /locus_tag="LP433_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBL2004558.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            70931..71917
                     /locus_tag="LP433_000365"
     CDS             70931..71917
                     /locus_tag="LP433_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBL2004559.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            71907..72218
                     /locus_tag="LP433_000366"
     CDS             71907..72218
                     /locus_tag="LP433_000366"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBL2004560.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            72240..74021
                     /locus_tag="LP433_000367"
     CDS             72240..74021
                     /locus_tag="LP433_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBL2004561.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            74014..75390
                     /locus_tag="LP433_000368"
     CDS             74014..75390
                     /locus_tag="LP433_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBL2004562.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLLERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            75397..76032
                     /locus_tag="LP433_000369"
     CDS             75397..76032
                     /locus_tag="LP433_000369"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBL2004563.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            76062..77417
                     /locus_tag="LP433_000370"
     CDS             76062..77417
                     /locus_tag="LP433_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBL2004564.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(77609..79003)
                     /locus_tag="LP433_000371"
     CDS             complement(77609..79003)
                     /locus_tag="LP433_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL2004565.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLELLAS
                     GLSIVKEKIKKYEL"
     gene            79095..80066
                     /locus_tag="LP433_000372"
     CDS             79095..80066
                     /locus_tag="LP433_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBL2004566.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            80063..80845
                     /locus_tag="LP433_000373"
     CDS             80063..80845
                     /locus_tag="LP433_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBL2004567.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(81014..81385)
                     /locus_tag="LP433_000374"
     CDS             complement(81014..81385)
                     /locus_tag="LP433_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2004568.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            81519..81962
                     /locus_tag="LP433_000375"
     CDS             81519..81962
                     /locus_tag="LP433_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBL2004569.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(82005..82814)
                     /gene="yidA"
                     /locus_tag="LP433_000376"
     CDS             complement(82005..82814)
                     /gene="yidA"
                     /locus_tag="LP433_000376"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBL2004570.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(82833..84200)
                     /locus_tag="LP433_000377"
     CDS             complement(82833..84200)
                     /locus_tag="LP433_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2004571.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(84184..85014)
                     /locus_tag="LP433_000378"
     CDS             complement(84184..85014)
                     /locus_tag="LP433_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBL2004572.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            85177..85614
                     /locus_tag="LP433_000379"
     CDS             85177..85614
                     /locus_tag="LP433_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBL2004573.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            85690..86310
                     /locus_tag="LP433_000380"
     CDS             85690..86310
                     /locus_tag="LP433_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBL2004574.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            86499..87005
                     /locus_tag="LP433_000381"
     CDS             86499..87005
                     /locus_tag="LP433_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBL2004575.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            87022..87921
                     /locus_tag="LP433_000382"
     CDS             87022..87921
                     /locus_tag="LP433_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBL2004576.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            88008..88892
                     /locus_tag="LP433_000383"
     CDS             88008..88892
                     /locus_tag="LP433_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL2004577.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(89084..89155)
                     /locus_tag="LP433_000384"
     tRNA            complement(89084..89155)
                     /locus_tag="LP433_000384"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89120..89122),aa:Arg,seq:ccg)
     gene            89215..90549
                     /gene="rpoN"
                     /locus_tag="LP433_000385"
     CDS             89215..90549
                     /gene="rpoN"
                     /locus_tag="LP433_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBL2004578.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            90698..91789
                     /locus_tag="LP433_000386"
     CDS             90698..91789
                     /locus_tag="LP433_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBL2004579.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            91830..92831
                     /gene="gap"
                     /locus_tag="LP433_000387"
     CDS             91830..92831
                     /gene="gap"
                     /locus_tag="LP433_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL2004580.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            92941..94131
                     /locus_tag="LP433_000388"
     CDS             92941..94131
                     /locus_tag="LP433_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBL2004581.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            94235..94990
                     /locus_tag="LP433_000389"
     CDS             94235..94990
                     /locus_tag="LP433_000389"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBL2004582.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            95106..96404
                     /gene="eno"
                     /locus_tag="LP433_000390"
     CDS             95106..96404
                     /gene="eno"
                     /locus_tag="LP433_000390"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBL2004583.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        32105 a        16506 c        20030 g        28030 t
ORIGIN      
        1 aatgaaaagc caaaacgaca agtaaaatat ttttttatat aaatatttgt gttactaatt
       61 ccgttaatat acataagtga aagcgtttta tataagaact tgaaaagaaa gaagggatag
      121 acatgaaaaa aagatacaaa ttggtgatag ctttgctaaa cattacccta ttattcagct
      181 taagtgcatg tggaaaaact aacgaagaag taacagcaaa catcgcagat ccaatgataa
      241 aaaaagccac tacattagaa gtatatgtcg caaacggcaa actgacaaac tatgttgaaa
      301 atgctgcaaa aatctataac cgcaaaactg gagcaaatat tgacttaaaa attgtgaatg
      361 tagcttcggg aacagcaaca gtacaaatga tcaccccaaa attggtaaca cacgaagata
      421 tgccggatat tatctccatg gcagacactt cagcagcagg tgtgctggaa aaatttcaag
      481 atgcttttta tagtgctgat gaatatggat tttatgacaa atatggcgat cagttttatg
      541 atcaaaaatt gaatattttg cgtcaacaaa cgagtaatga aacgattatt ccttgggcta
      601 gtgattttac cccagcactt tgttattatc aaccaaaaaa atttgctgaa ataggtgtag
      661 attttgaaga aatcagttct tgggaagaat atatccaggt ggcaaaagca ttaaaagaaa
      721 aaactggtag ttttggaatt gccttgccag aatctgggga ccaagaattg tttatcaaca
      781 tgctagccca gcagaatcaa tctttgcttg atgaagaagg aaatatccgt ctgaatacta
      841 aagaagcgaa acatgctgca aagttaatca aagaaatgat cgactcagat attgtacatt
      901 tctacggtgc acaagatgct gagaaagcat ttcaagaatc tgcaatgttt gttgctggcg
      961 gctggtatgc tacgaatatg tctttgaatt ttcctgatgc atctgacaaa tggcgcatgg
     1021 ctccactgat tcctttttca aaagaaaatc caggaaaagg tgcagtatca ggaggatcaa
     1081 gtttttatgt ccctaaagat gccaaaaatc cacaagtggc acaacaattt cttacattta
     1141 tgctgacaga tgaagaatgc ttagccaacg cactggagct gggcgtggct acatctaact
     1201 cattggccta tcaaacagaa gcagctgaga aaaagtttga ctactaagga ggacaaaaat
     1261 actatgaact attgaataaa atcaatgaaa atacatcaaa tactgtttta ccagccactt
     1321 attcagatgc tacgtcttat ttgactaccg ctgcatataa ctattggcaa acaggtgatt
     1381 ttgaaaattc atatctaaaa gaagcagaaa attttgctca taagtacggc gtaaaattaa
     1441 ctggtgatta aaaaatatta ggaggactta acgatgatgc aatcttcgtt accaagcaag
     1501 acaataaaga acagcaagaa aaaagcaaca gatacgtctc ataaaaaaag tgcttatgga
     1561 ttggtcacac cttttgttat tttctttatt gtgacgattt tgattcccat cattatctcg
     1621 tttgctttta gttttatgaa aattggctac tcatttgaat ttgttggatt tgacaattat
     1681 ctagctatct tccgagatcc attgtttatt aaatcttaca cgaatgtttt gattatcatg
     1741 gcaggatcaa ttccaataac gatgctatta gctatttact ttgctgtttt attgaattca
     1801 gcacagttaa aaggaaaagg attttttaga actgtctatt atattccaac cattacatca
     1861 acggtggctg tagcttccgt attcatgact tttttcaatc cgactgggtt attcaatgga
     1921 tttttgaatg cgctaggaat taacggtgta cagtggttaa caaatccttt ttggatacga
     1981 atatcaatga tcatcacgat gatttggctt agtgtaggat ataacactat tttattttta
     2041 gctggtcttc aagggatttc taaagagata tacgaaagtg ctgaaataga tggagcatcg
     2101 aaatttcggc aattcttttt attaacgatc cccatgctaa agccaatcat tttaatggcc
     2161 acagttttag ccactatcaa tggcttgggt aatttcaata tcccaaatat attctttggg
     2221 acttccaatg gaccagaaaa ttcagctttg gtcgtaggag tcaatttata taaaacaagt
     2281 tttgaaatgg ttgattttgg aaaagcctct gctattgcct ggacgatggt gtttgtatct
     2341 gttatattat cggctattca atttaaattc ggaggtgata aaaatgacta aacaaaagat
     2401 acaaagcaga atttttacgt acgtcattat tgtgtttggt gccttaatat ttttgatgcc
     2461 atatttatat atgattgtag cttcaacgca aagtaatcaa gaaattttaa gtggcggaat
     2521 caatttcaag tttggggata tgctattaaa aaactggcaa gccatcatgg cgagatataa
     2581 ttatcccttg attatttgga attcgattgt tattgctgta atcagtacag ttttagctac
     2641 agccagttct acaatggcgg gttatgcatt agcaaagtat cgttttatgg ggaataaact
     2701 gttgttcaat acagttatgc tatctaggat ggtgcctttt tttaccacat tgattccttt
     2761 attttacatt atgagtcgtt taggattatc gaatacttat gcaggtgtga tcatcccttc
     2821 gattgccagt acaacttcag tgtttatgat gcgacaatat agcagtcaat ttcctacagc
     2881 actgatggag gctgccagaa tcgatggtgc caatgagtgg gtgattttta cgaaaatcgc
     2941 tgtaccgatt ttatcaccta cgattattac tagtggttta cttatcttta tgggaagttg
     3001 gaatcaatat ctatttccat tagtcatgct ttcagataaa gataaatata cggttccctt
     3061 aattatcaaa aatatgacgg tttctagtac aggtgagcca attaattatg gcgcaattat
     3121 gctaatttta gcaacttcag tgatcccaat ggtcttgatt tatgtgtggg cgcagtctaa
     3181 atttaaggag aatgacattg gagctgcaaa taagtaaaaa aaataacgaa tgttaaccat
     3241 ctagttcgtt ctaggagcaa ctccacattc ataaaaatta aaagaatggc gggatatcca
     3301 tgaatgaaca gacgaaggaa tggtcaagaa aaattttgaa tgtagcttct gaaaagatag
     3361 atgcggaatt agacagaatg gggaataaaa ttccatatat ttcttacaac ggaaaatata
     3421 cagacgtaat aaaggacaga ggaatcgact ggtggaccaa tggtttttgg agtggtattt
     3481 tatggcagct ctttcacaag acaaaacgag aaaagttcaa agaggcagca atacaacaag
     3541 aacaattatt agaatctgcc ctgtaccatt tttcagacgt tcatcatgat gtaggttttt
     3601 tattcttacc atcggctatt gcacattatc aacagtctca aaacaaacat agtcgacaac
     3661 tagggttaca tgcagctacg gtacttgctg gacgctataa tatttcaggg aactatttag
     3721 tagcatggaa tgaccataaa cctggttgga tgattattga tagtatgatg aatttaccat
     3781 tactgtattg ggcttcgagg gaaactggtg atccgaggtt ctctaaaatt gctcggcagc
     3841 atgcagatac aacagctaag tatctagtga ggaaagatgg atcaaccggg catatcgcag
     3901 aatttgatgc agaatcaggg aaatatattc ggttacttgg cgggcaagga tacaatgaga
     3961 attcttgttg gagcagagga aatgcatggg ctttatatgg attcgcgtta agttatcgtt
     4021 acacaaaaaa tccgtactat ctagctatag cagaaaagat agcagtaaat tttattcaga
     4081 aaatcgaaaa aactggttat attcctctca ttgattttgc tgtaaaagat tcgaatattg
     4141 ataccagtgc tggagtatgc gctgcatgcg gtcttctgga attagcagga tatgtttcct
     4201 ctgtacgatc aaaaatgtat catgaagctg ctatcaatat actccaaaag acagaaaagc
     4261 actatgcaaa ttggaatatg gatgaagatg ggatcattgg aggcggagca gaagcatacc
     4321 atagagaact gacttataat gtgccactga tctattctga ttattttttt attgaaggct
     4381 tacttcgatt agaacagtcg gaattagcta tttggtagta aaaagaggag aaaatacaat
     4441 gaaacatcca gtaccactat taaggaccag acaggattac tttgacttat ttaaaaagat
     4501 aaatcaacca ctccagccgt tttatcgagc aagtggcgca caaattgatt atatacatca
     4561 aggggtagga tatggaaata aaattgcagg aatggaagga ttctctcggg ttttatgggg
     4621 agcggggccc gcaattgacc aattagatga acgatggttg aaattaattc tatcaggaat
     4681 aaaagctgga acagatcctt cccatcccga ttattgggga gaaatacatg aaagagacca
     4741 gcgtatggta gaaatgcccg caatgttatt agcgttatat catcatgaac aattattatg
     4801 gaaaaaatta gatacaggag aaaaaagcca gattattcat tggttctcgc aaatttttga
     4861 atatgaatgt gcagatggta attggcaatt ttttaagata attgtcggaa caattatcca
     4921 aaaatttggt tatccagtta aagaatcagc actgaaagaa gcatttgata atatagaaaa
     4981 ttgttatctt caaaatggct ggtatcgaga cagttcaaga ggtcgccaag attattataa
     5041 tccttttgca tttcattatt atggtttgat ttatagcgta ctagaaccag aaaagcccat
     5101 tagccagata tataagaacc gagctattga tttttctaga gactatattc atttttttgc
     5161 ggaagatggt gcaaatgtgc cttttggtcg aagcatgatt tatcgttttg cagtttcaag
     5221 cttttggtca gctatgttgt gggccgatct tttgcctttt aaattaggtg aaatcaaggg
     5281 gttagtcaat cggaatataa gatggtggat gcaaaaagaa atatttgatg aaaaaggtat
     5341 cctgaatatt ggttatacct accctcaatt gacattgact gaaccctata atagtacgtt
     5401 atctccatta tggctgaata agattttttt attgttggcg ctacctgaag accatgagta
     5461 ttggacggct aaagaaatgc ctatgcctat tcgtgaagga actaaacttc tttcagaagc
     5521 caatttgctc atacaacatg ataatggaca tacatttttt ttgaatgcgg gacaattagg
     5581 gccaaatttc catacattga ccaatgaaaa atatttaaaa tttgcttatt ctagtcaatt
     5641 tggtttttcg ataccgcgag cgaatcaatt gaaagcagaa atggcaatgg attcaatgct
     5701 agggattcag cgagcggaca catatatcac gaccagtttt aagaatgaga gcatcaaaac
     5761 ctatggacag ttcatcgttc gaaataatgt acgagacatt gtatgtaaga aagaggtact
     5821 tgcctctaca tgggaaccta ctttacaggc aaaaatcaga acttggctta ttccttttga
     5881 aggctggcag attcgcgtac acaaagtaga attagataca gaatatgttc tatatgagac
     5941 agggtttgct attgaatgtt ctcctgagaa agaaggaata atcatagaag aagacaagga
     6001 aaactatagg gtgagtgaag ctggcttttc aggtattatc tgtttaagtg acgatactat
     6061 taaacgaaaa tccacagcta ttatgggttt gcccaataca aacttgatga catgggaaaa
     6121 cacttttatt cctggattag agggtacatt tggaaaagga acccattggc tcggaacagg
     6181 agtggttgct catcaagatc gggattatag tttagaagta tggaacaatc gtcccaaaat
     6241 tgattttgat gggacaaccg ggctaactat ccaaaataaa aacaataaaa aaagactaaa
     6301 attatgctaa aggctggtgg ggaaatgctt gataaagtga tgtttgaaga gataatacat
     6361 ccagaaaaat ggataaatga atgttataaa gaattaatgg aaaaagaatg gaataatgag
     6421 atcgagcgtt gtcgcagaca cacggagagg ttaatcaaac gtatcagtaa cagtcagtat
     6481 caattcccaa gcgagtgtcc tataaaagga cgttatccat taagagacaa tattggttgg
     6541 acagaaggat tttggacagg aattaattgg ttgttatttg agaagacggg tgatccttta
     6601 tttcaacaaa cagctgaaaa agcagatata gattttatcc acaggattga ctgtcaaatt
     6661 atcactaatc atcacgatct tggttttttg tattctttat caaccgtagc agattataaa
     6721 ataacgggaa atcgaaaaat gaaggaagct tcaattgatg ctgcagaaac attacttcag
     6781 cgtttttggg agaaggcagg agttatacaa gcttggggag atcctagtga tccttcacaa
     6841 caaggtagaa tgatcatgga ttgttgcatg aatcttccat tattgtattg ggcgagtgaa
     6901 gaaactggaa atcaaaaata taaaaaagct gctcaggctc atattcaaaa tgcagcagat
     6961 tatttagtaa gagaagatgg ttcaacttat catacatttt atatggatgt caaagatgga
     7021 aaaccaagat atggaagtac gcatcaaggt tatagtgata attcctgttg ggctagaggc
     7081 caagcatggg ggatttacgg ttttgcatta agttatcgtt atttgaaaga acaaaaatat
     7141 tttgatttaa gcaaaatatt agccaattat tttatgaatc ggttgccaga agataccatt
     7201 tgttattggg atttgatctt tgatgattct agcagagaag aaaaagatac atctagtatg
     7261 gtgatcatgg tttgtggatt attagaatta atagaatcag gtctattaga caaaacagaa
     7321 aagaacttat accagtctgc tgtttggaaa attatgcgac aattgaaaga aagatatgct
     7381 acaacggaag aagaagatgg ctttttaaca cagtctgttt ataataagcc caaaaataat
     7441 ggggtaaata caccttgtat ttggggtgat tactattatt tagaagcttt agtgagaatg
     7501 actagtaatt ggtcttctta ttggtgaaaa aggtaaatat ggaatttttg tttgataaaa
     7561 taaaaaaaga aaaaccaaaa cagcatgaat ggtttctgtt ttggtttttt cgttaatttt
     7621 catattcttc taattccaag cttagttctt cccattccgt caattttgtt tcttgatctt
     7681 gtctagcagc ttctaaatct tggttcagct cattgagttt tacgtgatct tccaggtttt
     7741 ctggcgcgac catttcttgt tccaactgat cgatccattc atcgatccgc gccatttctt
     7801 cttcaacctg agtaattttt cgttgaaggc tacggataag cttttgctgt tctttgcttt
     7861 ggtaataatc agatttgttc gtgggagcag gagcagattc tggctcatct tgtgccaaca
     7921 attcggcgat ttcttcttct tcctgctttt tctctaaata ataatcatag tctcctagat
     7981 agactttgct gccattttca gagagttcga cgacttttgt cgcgatccga ttgatgaaat
     8041 atcggtcatg ggaaacaaaa agcagtgtgc cgtcataatc gatcaatgca ttttctaata
     8101 cttctttgtt gtcaatatct aaatggtttg ttggttcatc caaaatcaaa aaattttctt
     8161 tgttcatcgc taacttggct aaagcaaccc gtgctttttc accgccactt agcagaggga
     8221 ttggtttttc tacatcttcg ccagaaaata agaaagcacc taaagcactt cggatctctt
     8281 tttctggagt ggtaggatgc tcatcccaca attctgctag gatcgtcttg tttgtatgca
     8341 gatcagcttg accttgatcg taatagccga tggtgacatt tgtccctagc gtttcttttc
     8401 cacggataaa agggatctgg tgaatgattg atttcagcaa cgtcgatttc ccgataccat
     8461 tcggacctac tagagcaatc gcttcttgac gacggatatc tagattgatt ggttcagata
     8521 aggtgacatt atcatatccg atagcggcat cttcgatttg caagactaca tttccagaag
     8581 gcttttctat actgaataga aagtttgctt gtttttcatc cccttgagga cgatccagcc
     8641 ggtccatttt ttctaatgtc tttctgcggc tttgcgctcg ttttgtggta gaggcgcgaa
     8701 caaggttccg agcaacgaag tcttctaatt tatggatttc tgtttgctgc ttttcataag
     8761 ccttccattc acttgctaac tgttctgctt tcaaatctag atatttcgaa tagttacctt
     8821 tgtaatggcg catttttctt ctgcttaatt catagacttc attgactact ttatctaaaa
     8881 aataacggtc atgggaaaca atcaataatg caccagtata gctttgcaga taattctcaa
     8941 gccaggaaag tgtctcgata tctaaatggt tcgttggttc atctagaatc aaaatgtcag
     9001 ggtgttgcaa aagcatgcga gctaaagcta aacgtgtgcg ctgtccgcct gataaagtat
     9061 cgattttctg atcataaaat gaagaatcga atttaaaccc atgcaatacg gaacgaattt
     9121 cattttcata accatagccg tttcgatctg aaaaatcgtg ttgcagccgg tcgtattctt
     9181 ttaaataaga actataagca ggtgtgtctg gcgtaccttc gctaatgaaa atctctagct
     9241 cgcgcatccg ctcttccatt tgtctaactt gttcaaaagc tttcagcatc tcgttccaaa
     9301 ctgtttcatt ggaatcaagt cctgtgtcct gagcgaggta tccgagagtc gctgttttat
     9361 ttttagcgat ctttccttca tcaggtgctt caattccagc aatgatcttt aataaagtcg
     9421 attttccagc gccatttctg ccaactaaag cgacacgagc gcctgtactg atttctaaat
     9481 gtatgttttc aaataagact tctgcaccaa aatggcgagc aatctgattg gcttgtaata
     9541 atatcatgga atcctctttt ctactttgtg aattctcctc aaataaaaaa ctatttttca
     9601 attagtagtc taccataaat tccattatac tgcgagattt gcagaaatga taaataaatg
     9661 aataaagaat aaaatttcac aatatctgag caatggaatt gattttttcc tataaatact
     9721 gctatgatgg agaaatcaaa gatgtaatta gacaatacgt ggaggtcatt tcgtgaaaga
     9781 tcatattatt ccaaaggcga cagctaaaag actgcctttg tattatcgct atttaaggat
     9841 tttaaataat gctggaaaga aaaaagtgtc ttcaactgaa ttaagtgaag ccgttcaagt
     9901 agatagtgca acgatccgtc gagatttttc ttattttggc gaattaggaa aacgtgggta
     9961 tggttatgat gtagaagatc ttatgcactt ttttgcaaag acattaaacg acgatcaatt
    10021 gacaaatgtt gcgctgatcg gtgtagggaa cttgggaagt gctttactaa aatacaaatt
    10081 ccatcaaagt aatagcatac gtatcagttg tgcttttgat gtgaatgagg aaatcgttgg
    10141 gcgcatcgta gacggtatcc ccgtttatcc aatggaagat atgtcagaac aaatcaagat
    10201 ccaacaaatc gaagtagcaa ttttaacgat acccgctgaa agagcacaag aagtagtcaa
    10261 tcagttaacg gaagcaggaa tcaaaggaat cttgaacttt accgctgctc gattgaatgc
    10321 tccgtcagat gtattgatcc aaaatgttga tttgacgaat gaattgcaaa ccttgatcta
    10381 tttcttgcat tctgacgcaa atgcgcattc cgaaaataca gcagaataaa aataaaaagc
    10441 gattgaacaa atgaaggcaa aactttcact tgttcaatcg cttttttctg tttggacaac
    10501 gattattttg ttcggaagat ttcttcataa gaaagggaat catcttctgc tgtcagttca
    10561 tctagtagat aacggatttt tttaaagtcg atgaaccgtg cttgccgaaa gacttctttt
    10621 ccttgatgaa aaatcaggac aactggcgca gtcagcactt caaatttact agctacttct
    10681 ggtgtttcaa atgcatccaa atgaagtgcc ggaatatcat aatgtgtgag aagttcctct
    10741 agtcgtggac gaacagcgtg acaaacactg caattaggca tcgaaagata aatgacggca
    10801 acggatgact gttgcagtat gtcttgaact tcagtcaagt tagtggtttg tttcattttt
    10861 attctccctt ttatgataga agtgatatgt atgagacctt aatttaatgg gaataacaga
    10921 aaaagtcaat tgaagtgctt tggtaaaaaa taagagttgt gtaaaaattt acagagcaac
    10981 ttgttttttt tgaataaaag cgtatatttg caaagcgaat gaactagaaa taaaaaggag
    11041 gaaactcatg ttttctttta ttccaaattc ggttttgcag atgagtacga ttttcttatc
    11101 gatcgttatt gaagcattac ctttcgtatt attaggctgt cttatctcag gcgccttaca
    11161 agtatttttg accccagaac gtgtgaagag atggcttcct gaaaatcgta tcttctctat
    11221 ttttactggt tcgatcttag gatttttctt tccttcatgt gaatgcggca tcgtaccgat
    11281 cgttcatcaa tttgttaaaa aaggcgtacc agttcacaca gcgtttgctt ttatgctgac
    11341 tgctccgatc atcaatccaa tcgtgatttt ttccactttt atcgcatttg gcaattcttg
    11401 gcagatggca agctggcggg tgataggcag cttttttgtt gcccttgtga ttggtgtctg
    11461 gcttgcctat tttcaaaaag acgctgtatt gaaagaaaaa atcacgtcta aagtagcaga
    11521 aaatcaccat catcatgtcc atgaagaaga acaaagtgag aagaatgaac caaaaaatca
    11581 gctgatccat caaactgggc atgtgttgac acattcaatc gacgaatttt ttgatacagg
    11641 tcgttatttg atcattggcg gattaatcgc agctgcgatg cagacttatt taccaactag
    11701 aattatgcta acgctcggct caacaaagat tttagccatt atcatcatgc tgttattggc
    11761 ctttacgatg tctctttgct cagaagcaga tgcgtttata ggatcttctt tgttaagtct
    11821 gttcggcaca gcacctgtag ctgccttttt ggtctttggc ccaatggtcg atatcaaaaa
    11881 tctactgatg atgaaacgat attttacagg acgctttatt ttatcgctga tcggactgat
    11941 tgcccttagc gttattggat tcacattatt tatttaggag ggaaaatatg ctgcggtttt
    12001 tgattttatc tgggtatttc gaattgatga tgtacttgca agtttctggc aaactcgatc
    12061 aatatatcaa tgtccattat cgctacttag ctattctttc aatgatttta tctgctcttt
    12121 tggctttagt tcagctgtat ttgtgggtca aaaacggaaa agcagaagaa aaggcacacg
    12181 agcacgatca tgaccatggg ttgtcaaaac cttatcaacg tggaatcgct tatgtactgc
    12241 tagctttgcc agtaatcgtg gggacgttgt ttccaacagt tagtctcgac actacgatcg
    12301 tagaagccaa aggatttaat ttcccagtaa gtaaagaatc agtaggggat ccggagatgc
    12361 agacacaata cttaaagccg gataccagta tttatttcaa caaatcagac tacttagacc
    12421 aaatgaatga gttgaaagaa aagtatgggg ataagcaaac tatcaagatc acagatgaaa
    12481 actatttaga agttatggag ctaatttata attaccctag cgaattcatt ggcaaaaaaa
    12541 tcagctatga aggatttgtt taccaaacac cgaacgatag caatacagat atcttcttgt
    12601 tccgattcgg cattatccat tgtgtggcag attcaggagt ctttggtttg ttgacgcata
    12661 tgccggaagg agtaacggtt aaaaatgatg aatggtataa aatagaagga accatccaat
    12721 cagactatta tcaaccattc aagcgtgaaa tcccatctgt agttgttaca aacgctgaga
    12781 aagtctctgc tccgaaaaat cagtatgtgt atcgttcttt ttaaaagaac aaaataaata
    12841 aacatagctc agacagctga cacgcaagga cgtcggttgt ctggcttttt ttgcatgatg
    12901 tattcatttg tttgatattt attttagaag cagcatcctg aaagtatttg atatcggttt
    12961 caaaggtgtt ggaaaagatt gtgaagagaa ttacaattta ttcctaacat gtatgttgaa
    13021 aagttgtatg aaatgatttt gatagtaaaa tatcgagtgg aggtactttt tatggtaacg
    13081 cgtatattta ttttggatga tagtttggtt tttgaaaaaa tgctagtaga aattttggaa
    13141 gaatccagaa ttttattaag tccttggaaa tttgagatcg ttcagggatt gaacgttata
    13201 caatttgttg aattcattaa aaataatgaa atctattcct cagatatttt tttcctagac
    13261 atcgatttga acgcctatta tagcggtatc gaactaggcg aaatgcttag agaaaagaat
    13321 gaaaagtgta aaattgttta tctaacgtct catccgaata aagcaataac tgttattaat
    13381 cgaaagatta cgcctagtgg ttatttgata aaagaattca cttatgaaaa aaataaaaaa
    13441 agcatccaaa gttacttatt gaaagaaaaa gaaaactatc ctgttcaaca tgctacgaaa
    13501 aaaaggtgga caactgtccg ttatggtaat agcgatcact atatccatta cgatgaaatc
    13561 ctttatctaa tgagcatgcc aggttataaa aataaaatag gcctagtatt gaaagatgaa
    13621 gagattctcg taaacggcac aattaaaaaa tataaaaaat cactcgaata tgagtattta
    13681 tgtaaagatt taaaagctta tatcattaat actgaaaaca ttacatctat tagcagagta
    13741 aacgaaatag taacatttgc aaatggagaa caactagaga tgggaaagag aagtattgat
    13801 aaactaaaga attttatgca agaaaagata gaaaatgaat cattttaaag aaaacaaaga
    13861 ctcatatctt acctgttaga agagtgtttt cctgtagaag agaacaaccc aagtagcagc
    13921 ctagtcgttt ctatcctttt ttgttatgca ctctttttga catttactcc accaataacg
    13981 aagggtacaa taaaaagtaa taacaaacaa aaggagtaca gaaatgattg aattcatcaa
    14041 tgtaagtaaa agttacggga aaaaacaagc attaaaagac ttgtctctct cgataagaca
    14101 aggggaaatt tttggatttt taggacataa tggtgccgga aaatcaacta cgattaaaag
    14161 tttagttagt attattgaac catcatcggg aacgatttta gtagatggaa tgaaattgac
    14221 ggaaaatcga ttgagtatca aacaaaaaat cggttatgtg cctgattccc cagatatttt
    14281 tttacaattg acggctggag aatattggga cttgatttca gctgcctatg aattagacac
    14341 acaaaaaaaa gaaaagcgtt tagcagaatt gacagcgctt tttgatatgt atagtcatca
    14401 aaatgaaaca atcgcaagtt tttcacatgg aatgcgtcaa aaaacgattt tgatcggcac
    14461 gttgctgcca gatccagata tttgggtatt ggatgaacct ttgcaaggac ttgatcctca
    14521 agcagcattt gatttgaaag aaatgatgaa ggctcatgcc gcaaaaggaa aaacagtcat
    14581 tttttctaca catgtattgg ataccgcaca acagttatgc gataaactgg ctattttgaa
    14641 gaaaggtgaa ttgatttatc agggggcagt tagtgaatta ttgaatggct cacctgatga
    14701 aacgctagaa aagatttatt tgaaaatggc tggaaggcaa gcgacaggag atggaccgta
    14761 tgtataagcg acaattatta gaattaattc gagttaatct tttatatgtt aatccacagc
    14821 tcacgaataa agcaagagag aaaggaaaaa agggaaagcg attaactatc tatcttttgt
    14881 ctcaaaatct tttttcaggg ctgatttttt tactgattta cggatttgct atgtttgcta
    14941 tgaactttgt taaattgcca ggtttcttta cttattacgt ggcacttttt ggtatgttag
    15001 gtttaactca aagtatatca gtcatttata atatcttttt tgaaggaaat gacctgcaag
    15061 tatttttgcc tctgcctttt ggacaagaac aggttttttc agcaaagatt ttggtagttg
    15121 ctttgaccat cattcctttt gtttttccgc ttctagtcat gtttatttta accggatggc
    15181 gagctgatct agggattttg cttactatca ttatctcaat ccttttgttt tctctatttt
    15241 tgattattct tttttgtctg gctagtttga ttgtttttgg tttggctcga acagcagtgt
    15301 ttaaaaaaca tagaaaaaca gtttctagta tcttgcttgg cagctcgatg ctgatcgcat
    15361 ttgctggaat catgtggatg aatcatcaaa cggggactat tgaaaatgag ttaacagatc
    15421 ggcatccgat ttcgatatta ttgccattct atgatgctgc cagtcagcca ctttctcaac
    15481 aaggtttatt gggttgggga atactagcta tcacggctct gggatttttc cttgctgtaa
    15541 aacagctgat agtaccaaag cttacagagc aactgactga ttcaaacagt gagttcaaaa
    15601 taaaaagaac ccataaaaag aaccaaaatg tgcatcagct tttatttagt tacaatgctc
    15661 aattagtaaa agaacctaat ttgattatgc aagttctttc ttcttccttg ttaactccaa
    15721 tcatttttat tcttgctttt gccctaggag gcgaaataaa attaactgat ttagataata
    15781 agttaatcgg tgttgttttc ctggtaggga tcgcattggc tttcttaaca gttaatcaga
    15841 cttcttttat cagcaatctt atttctttgg atcaagaaaa ttttctgttt atccgttctt
    15901 tgccaatctc tatgaaccaa tatttaaaag aaaagttcag attcggatgg atattgcaga
    15961 gttttttaac tggtgggatc gcattattaa gcggactgtc ttttcagctg cctttgtttt
    16021 ttatccctag cttgctattt ggttctttat tcggctgcta cttattgtca ctacgttatt
    16081 tcgctagaga ttatcggttg ctgctgctga actggaccaa tattaaccaa ttatttaaca
    16141 gaggttcagg aagtttgggt ttagtcgcaa ctatgatggg ttcattgatc atcagtatta
    16201 ttcttatcgt cttatacgga atgttggctt tgttttatcc attttggtta gtgaatattc
    16261 ctgtgatcgg tttagttcta atactttccg ctctatggat cgtttattat caacgaacgt
    16321 tttggaaaaa atttgaataa agaagagggg ccgtgacaaa aatcatgtcg cagccccttt
    16381 tttacagata gagggtgttc aaaagtcagt ttctcagtat taagtcaatt ttatgtaaaa
    16441 atgtgagaag ctatttttac aaaacttttt ttaatactca taattacttc ttattgctcc
    16501 tgcggttact tgtcgcaatg tttgtgagat attttgtcat cgctcaaggc tgaacgtctc
    16561 tttcacaacc ttttctttgt tacacttcgt ttatttaaaa agccgttttt ttcgtttcat
    16621 catgattgcg tcacgcttta ctttgaaatt acggatgtta tggttaaaga cttctgataa
    16681 tacaagacct aaagcgattg ctccagcaat cataattgct tggaccgcat aatgagccgc
    16741 ttctcgatag gattcagtaa cgagatttcg aaccgcttga taagctaaac caccagggac
    16801 tagaggaacc atcccgggaa tattgaaaat cgttacgggc attttcaaac gtttagagaa
    16861 aagatcgctg atgaatgcta ctcctaaaga accaagcaat gaaccaaaag cagcagatcc
    16921 gcctatttga acacagatcc agtagatcat ccagccaaaa gcaccagaaa gaccacaaca
    16981 aatcaatgaa cgcctaggta catttgtaat aacggcaaat gccgcagtcg ctaaaaaact
    17041 aaaagaaaac tgaataaata tcgtccccat acttgtgttc ctttcctaat aaaaaagctg
    17101 gaaaataaaa gcaatcgcaa aaccgatcat cgtagcagtc atcatcgctt ctgttccgcg
    17161 agaaactcct gagacataat gtccagctag caaatcacgg atagcgttcg taatttgaac
    17221 tccaggaact aaaggcatca cacatccgat aatgattaga tcctgattgc ttcctaagcc
    17281 aaaacgtacg ctgtagatag cggctatgcc aatcaataaa gaagataaaa attccgataa
    17341 aaatttgatt ctaaaaaatt tcaaactata tagataagct gcgtatccca atcctccaat
    17401 gactaaagtc acaggtaaat cggtcatctt tccgccaaat aacaccataa ttgttccact
    17461 gatcactgcc gcgctaacga tttgcaacca gacaggaaag aaagaacggt ctcggtcgat
    17521 tgcttgcagt tcgcagtaaa gttcttctaa tgttagctct gaagcaacat atttacgtga
    17581 aagatcattt acttttacta ctttttctaa attaatcgaa cggttggtaa tttgttccat
    17641 tcggatggtc gaggtacgat caagaccaat aaagagaccg gtttgagtga catagctgac
    17701 caaacggaaa tttccagaag ctaaagcaat tcgactcatc gtatcttcta cccgatacat
    17761 ctccgcattg ctttccatca tgattttccc agcgagtaaa caagtgtcca gcaacagatc
    17821 taattctttt cccgtcatag catcttctcc aataattgat tgattagttt tattttacta
    17881 caaaacatac cagaagcgta aagaataaaa aaacttgagg aaggaataaa agaggcgtat
    17941 actgtttttg tattgcgggt gtagtttagt ggtaaaatcc cagcttccca agctgatgtc
    18001 gcgggttcga ttcccgtcac ccgcttaaaa taggttgtga aaaagctgct ctgcaacaag
    18061 taataagaac agccaagcaa aaacaacttc ttatgttttt aacttggatg gacttattac
    18121 cgcagatgca agcttttgcg caccgtttac caagcggttg tgaaatcagt gtattgtctt
    18181 gagtatgaag aaaatttttg aataataata aataccttac agatagagtg gtgactgatt
    18241 agagacgagg aatccgtctc ttttttgtat ttttaagcca tcttaaaaca ggttttattt
    18301 tttgctgttt ctatttcttt ctagtattta tttatagggg aacatatgtt aagatttagg
    18361 gagctgttag taaaggagta aagaaatgag caaaaaaaca accaaggcga tcgtggggat
    18421 cgtcgctgct gtgattgcag gggcattcgg tgtttccacc acacaaaaag attcagatat
    18481 ctttcagcag attacaacta tttttgattc cacaccacaa gcttctcaag tagcggatgt
    18541 gccagaatat gatggaaaac atcaagaaat agaaatcaat gggaatcagc cggaatttac
    18601 aaaagaggat cttagccttt ccaaaggaac atgggaaagc tattcaaata ttgataaatt
    18661 gaacagagta ggacaagcca atgctatgct tggaaaagat ttgttcccta ctgaaaagag
    18721 agagcctttg tatattgacc cgacaggttg gaaacaaaag aaattaagtg acgggcaatg
    18781 gttatataat cgcagccatt taattggttt ccagctgact ggtcaaaata acaacattaa
    18841 aaacttgatg acagggacac gttcgttgaa tgctccatac atgcttgctc acgaaaatga
    18901 tattgcggca tatatcaaag aaacaaatca tcatgtacgc taccgtgtca ctcctcattt
    18961 tgaggggaat gaactggtag ccaggggagt gcaattggaa gcagaaagca ttgaagacaa
    19021 aaaaattgaa ttcaatgtct ttatctacaa tgttcaagat ggctacacga tcaattatga
    19081 gacaggacaa gcaacaaaaa caaaaaatta gtagcagcta ttcgaatttt ttatgaatat
    19141 tatgaaaaaa ttgtgtaaaa acatacattc aaagaaatat agcgtatact ttatgaaaag
    19201 agtacttttg ataaagctac agaaaaaagg aaaaaaacat acaaatagtg tttcttaatt
    19261 tattcggaag tttggaatat ttgtttgtag ttttcccttt cttcgagtaa aataaggttg
    19321 tagaaggtaa gctggaatta ccttgcggga aagaggtgta gaatcatggg ttttacagat
    19381 gaaaccgtac gttttggttt tgacgatagt cgcaaaaaag aagtgagcga aacattagcg
    19441 attgtttatc gggctttgga agaaaaaggc tacaatccaa tcaatcagat tgtcggctac
    19501 ttgctttctg gagacccggc ctacattcct cgttatcgtg atgctcgaaa tttgattcgc
    19561 cgtcacgaac gcgatgagat catggaagta attgtcaagg actacctctc aaatcatgga
    19621 gtgaatttat gagagtaatg ggcttggatg tcggttctaa gacagtaggt gttgctatca
    19681 gtgacccctt tggctggaca gctcaaggag tagagatcat tcggatcaat gaagcagaag
    19741 aagagtttgg ctttgatcgg ttgaaggaat tagtagcaca atatgaagta gaccggtttg
    19801 tagttggatt acctaaaaat atgaacaatt ccatcggacc aagggcagaa gcttccatgt
    19861 catacggaga aaagatcaaa gaactattct ccttgccagt tgattatcaa gatgaacgat
    19921 taaccactgt tcaggcagaa cgtatgctag tagagcaggc aaatacttca agagccaaac
    19981 gaaaaaaagt catcgataaa ttagcagctg tgatgatctt acaaaattat ttagacggct
    20041 caggtaagca attattttaa taataaaaga aaagaggtaa tcttatgaca gaacataacc
    20101 attcccacga ccatgaagga cacgaacaca tcacattggt ggatgaccaa ggaaatgaaa
    20161 cattatatga aatcctacta acagttgacg gacaagaaga atttggacgt aactatgttc
    20221 ttttatatcc tgctggtgtt tcagaagatg aagatgtaga attacaagct tatgcataca
    20281 tcgaaaacga agatggaaca gaaggcgagt tagaacaaat cgaaacagac gcagaatggg
    20341 acatgattga agaagtattc aatacattca tggcggaaga agaagaatag actataaagc
    20401 taggagaaac cttgatatga tagggtttct ccttttttta ttttttactg tatgccatat
    20461 tgtatgccat ctagtcaata tttaagtgtt gtactaattt ttcaacagtc ttttctttcg
    20521 tttcttttgc caagtgaccg taacaatcga tcgtctgact aatttttgta tgccgtaatc
    20581 tagtttgaac ttctaccata gtagctccag cgtccaagag cattgaagca tgagtgtgtc
    20641 ttgctacatg cacaccgaga aatggaacca tagctttttc acaaatagta atcaatcttg
    20701 cataaatagc gtggtgtgtg attagttctt tatagatacc acaaaaaatc atagtcggat
    20761 cagttacacc aagtgtcagc atatatttcc gctgattaat ctgccatttt tttaatatag
    20821 aaattgttct ttcatctagt ggaagaaccc cagcactaca atcagtttta ggatcactga
    20881 ttttatagcc atttttggat tggcttagtg ttttattgat ggtgaccgta ttttcttgaa
    20941 aatcaatgtc tgaccaattc aatgcaaggg cttcactgat cctaaccccg ctataaaaga
    21001 gaaagcgtag taacgtttta tcaaagtcgt ttcgataagt ttcaggtttg ctgtttaggt
    21061 aatcaaacaa ggtgatcagt tgttctttac tgtaaacttt gaccttttct ttatgcttag
    21121 tggtggttct tttaggcatt aatacgttgt ctagtggatt agtctcaata atcccaagat
    21181 tgatagcgta gctaaaaata cgcttagaag ttgaatgaag taccttgtat tggtcagtag
    21241 tttcagccca gctatttaca atttgttggg ctttttttac cgtgacttca ttcacacgaa
    21301 gatttccata ttttggaaga atccactttc taaacttgat ttcagttttc atgaaggtgg
    21361 cttctcggac agtggtttta tatgtttcta gccacaagtc ataaacttct ttaaacgttt
    21421 cgttgttcgc ttttttaata ccgtttttat cgtagtccac ttgcaagcgt gacaaggcaa
    21481 gctgggcttc tttttttgtt ttgtaacctc gtctacgaac cttatcaggt ttgccagtca
    21541 ttttgttcat tccaagatag gcttcataga gccaaaattt acctttttta gtttcatatt
    21601 gcttgaatgt tgccataata gttttccctc catagtgtag caagccgtgg gggcggttgg
    21661 aggaggcagt ttattattat tttgaatagt gtttatttag ctcagtaaca agagctgtga
    21721 actcttttag aagatcattt tcataaaatt cttgatactc ttttttctca tctgtatttt
    21781 tttctgaatc attaattaat gagtcatatc gtaaaagcgt atttagaaga gctgcgagat
    21841 aagcaattgg ggtactcccg tcaggaaatt caattcgaga tcctgtttta agatatttta
    21901 ttgcgtttgt taaataaatc ttctgtgaga cagtcaggtt atcttcttcg atgttattga
    21961 tagcattaga aagattagaa tcaattatag agttattttt ttcaatagtt tttttcaatt
    22021 gcttttcaag cacatttcgc ttaatttcgg gcatcatatg catatctctt aatgtataag
    22081 atccgtttaa tagataggta gtggatacat ctaatacctt tgaaagttgt ttaagcctgg
    22141 tgttattggg aagattatag ccattttccc aattactaac ggcaccttta ctggccggtg
    22201 gggataattt acctccaagt tgttccattg agagtccctt ttcaattcta gccagtctaa
    22261 ttctttgtcc tgtctccact gcttcggggt atttttttct agccacattt tcaccaccat
    22321 tcatatattt tctctactat atcacgattt aaatatgtgt gaaacataaa agttcaaaaa
    22381 agtatgttaa aattcttgca aatgaaaagg tatgatggta tattgagttt ataagaggta
    22441 tagaaatgta ttcaagagcc tcttgcattt ttttaaaatc tttgtataga aatgtatgct
    22501 aacgaggggg gataaatatg gaattaaaaa ttgacaaact cacgcttgat gatccagctt
    22561 ttaaaattat tgacgatcga gttgttcaac aagtagagca aactcaagga acgttacttt
    22621 cattattaga aaaaaagtac cagtttccaa aatatatgaa caaggcacaa gctgctaagt
    22681 atatgaacgt ttcatacaat actatgatgc agaaatatgt tcctaacggt ttaaagttga
    22741 ttatagttga tggagtcgta agaatttcac aagatgaatg tgatcgcttt atggaagaat
    22801 accaaaaata aacgcaagcc gtgggggcaa agggattaat aggaggaaat aataatggaa
    22861 tcgacacaaa ataaagcaat cgaaaaagta ttatcaacaa ttcttacaga agacacagcg
    22921 gcagaattag caaacttgga aggcaaagcg ctagaagaaa cgtttgaatg tttgtacgaa
    22981 caaatggact atcaaaaatt gctaccacaa gaaccaacgg taagcggagt attgcgtggc
    23041 ttgaacgatt tagtacaagc agagtttaaa gaacgacttt ctattgaaga gtatcaagaa
    23101 attttgtatc agcaagttga gttgttagcg agcttgctag ggcttgaact ggaggacgtt
    23161 gaatgaaaac tgaaatttgg aacggacaca ttataagatt tgtcgatatt aatgatgaat
    23221 ggtgggcagt ggcgaaagat gttgcggaag cgttaggtct taaacaggtt actagagcca
    23281 ttcactcttt gcctaaagat ggggttacta ctagtaaggt catcgattca ttgggcagaa
    23341 cacaagatgt aaacatcatc aacgaaaaaa aatatttacc gcatggcatt caaaagccgt
    23401 aaaaaagaag ccgaggcatt tcaagactgg attttcgaca tcatcaaaga actacgccag
    23461 tccacaggac ttgaaggctt tcaagtattc cgcatgctag acaaagaaca ccaaaaagaa
    23521 gcaatgacta aattaagcca cgctattact gaaccaaaac cagtagacta cattaaagcg
    23581 aatgtgatag ccaataaagc tgtatcaact atttatggtc attccaaaat ggtaaaaaag
    23641 aaagatatga ctcctgaaat gttggttgat cgtgaaccta ttttagatga gacagtagaa
    23701 ttaatgactg ttaaagaaaa atatgggttg cagttttcag tgagtgagaa aatttataat
    23761 cgttctgctg aattgcagac aacttaggag cattaacatg atcgagaaca aagaaaaagc
    23821 cttatccata acagtcttgg cggacaggat aaaggcaact taattgggat aaaacccgat
    23881 attctttgtt ccgattatac catattaaaa aatcggaggg aaccattatg aaacgaaact
    23941 taattatagg aagcatttta atcggcggaa ttttcggctt attaccatta attgcaaaaa
    24001 tagctatctt tgcaggatta gcgttatatc tcttcactgc ttatgacgag tacgactatc
    24061 aattaagaac tggagggcat aagtagatgt acaaaacaaa actattaaac caactcgata
    24121 gccttgaatt agaggaaatt aatcaaggga tcgctgaact agaaaataat atcgggaaaa
    24181 cctactttgg aaattcattc aatgaaaaac taacagtttt gtatgtactc aaaaaacatg
    24241 cagaacacaa aataatttgt cgagaaatca acgagctaaa aaatcagatt ttaaccgcat
    24301 ggttaaacat tactgatatg caagaagcaa gggtgaaaac atttaataca tgggtaaagt
    24361 atcagaatca attaaaaggt gctgaatttg ttcgggatgg gttgaaatac gaacttgagc
    24421 agttgaagct catggaggtg tctgaatgat ttataccagt attttgaaaa aggaggagag
    24481 gtttattggc aaataattat caagcagcaa cggaattaca aaagtcggga tggtcaattt
    24541 atcccttatc tcctggaact aaaattccaa taaaaggctc tagtggttgg aatgatgcaa
    24601 ctaacgattc taatcaaatt aatgaatggt ggacggaaga tgcaactaga aatattgggt
    24661 taatgcttga agatcatcaa atggtggtag ttgacctaga tcaacattct gaaacacgaa
    24721 acggcgttga gaattataaa aaacttgctt caatgtatga tccatttcct tctacttata
    24781 cggaaatcac accaggtaaa ggaatccatt tcttctttaa aattcctgat ggtgtaatta
    24841 tccaacaaga aacaggtgca tttgctgata tcttcgggcg tgatgataaa ggtaaaagtt
    24901 taagcgggat tgatattatc actaaaggag ttccaatagc gccaactatg attatttcaa
    24961 gaagtgttgg gagagcatat gaacctattg aaaacgtatc tctaaataat attgcaccag
    25021 ctcccgattg gctagtgaac ctactgctaa aaaaaccgca agaaataaag actcaatacc
    25081 gacccgtagc aaaaacaggg acagcaaaaa aattagatat gattgttcaa ggcgctggcg
    25141 aaggtagtag aaacgatcat ttaactaagt tatgcggttg gttactatgg cacggtgtag
    25201 ataatcaaac tttagcagaa ttgatttata cagcaaatgc gtacaatgaa ccaccgctaa
    25261 aagataaaga agtgaatcaa attattcgat cgatgattaa aaaagatttg agggggaaag
    25321 ctcatggctc ataagcataa attagatagt attttagact ttcccgaagc cagcgagcgt
    25381 gaagacaata tcattgaatt gaaaacctgg atgtcacgat taagatgcaa taaagacgat
    25441 cagattaaaa gtaacagtgt tgtgaatgca gaattgattt taaccaatga tagcaattta
    25501 gctggaacaa ttgcttataa cgaatttagc ggatacattc acctattaaa agattctcct
    25561 tggatcaatc gtaccgctgg agaatgggaa gacagttttg aggatgcctt aacggcatat
    25621 attgaagaaa actacaatgt agtttttgat gacaacaaaa tacacaaagc agtagtaaat
    25681 gtggctagaa agaatgtttt caacccagta aaagaacgta tcgaaaaagt taaatgggat
    25741 caacagccta gactggaaac actgtttatt gaccttttag gggtagacga caacctttac
    25801 acacgagaag taacaaaacg ttggatagtc ggatcagtcg cacgtatcta taaaccagga
    25861 ataaagtttg agatcgttcc agttttggat ggaccgcaag ggattggtaa gagtaccgtt
    25921 ccagcattac tttacacgga tgattttttc accgattcat tagattcgct aggtgaaaag
    25981 aaagatgatt atatgcagct tcaaggcaat gtaattattg aacttggaga attatcttca
    26041 atgaacaaaa ctaaaattga acagataaaa aacttcatca gtgccaagat cgataaaatt
    26101 agacctcctt atggtcggaa tgtcatagct tgggcaaggc aatgtgtatt tattggaacg
    26161 tcgaatgatg ggcagtattt gaaagatgat acaggaaacc gccgttttta tcctttgcct
    26221 tgtaagaata agccaaagat gaatccgttt aaaacaaagg atgaatattt tcttcaagtg
    26281 ttagctgaag caaaggtgct ttttgataaa ggacaacgaa tctattttag tcccgatgaa
    26341 gataaagaag tcttagaaat tgcaaaagac tatcaagagg atgccaagat ggagaatcca
    26401 attaaagaag caatcactaa atatttggaa atggaaatcc cgtataaatg ggaagaagct
    26461 ccagcgtggg cgagacgttc ttattatcag aactatcctg acagtaaatg taatgagaaa
    26521 aatttacagc atttctataa tggagctact atgcaacaag agttttattt agttgatagc
    26581 gtactcaccg ctgatatttt ggaagctgtt tttgataaac aagcaaagga tttattgaat
    26641 ggtcgatcag atgcagaaac taaaaagatt gccttgatta ttagcagtat tcctggttgg
    26701 gaacggaagc aactgccaaa aagaaataaa cgacgaggat tttacaataa gtcaaatgcc
    26761 tatgaaaata aaaatcgagc tggaaagtac aaaaagtaac gggtagtaac gggtcagtaa
    26821 cacctagccc gttactagtt tacccttact gccccaaggg ataaagcaat ttggtaacgg
    26881 ggtaacacct tatttcctta aaacttttga aatagttagc taatatgctg gggaataatg
    26941 ttactggatt ttacccgtta cctgttacca aaacgctaga acccttgtcc ccgttgggat
    27001 tgagtggtaa cgggtacctg ttacgtaggt gttaccacgt gttacgaatc aaggaggaaa
    27061 gtaaatgctc aatattattt caacaaacaa agcaccgaac tttcaatata cagatgaaat
    27121 ggatcggttt ctaatgaaca cgctggcatt tagtgtggga ttggtaacag aagattattc
    27181 cacatttgat ccagaagtat taaagataat ggaagaagaa cctgattggc tgcaggagtc
    27241 agtagcgtgg tgtcaatcgc tagtagtggg atcattggta gatagtggca actatgatga
    27301 tacaggtgag ctaatggatg aatttaattg tctgcttaac ctatatgatc gagcgagaca
    27361 acgagagctt acatcgaatg aggataattt gtttttaaac atccatgata agttcttggc
    27421 tttgctacta acagatgatg aattgataac taatttattg gaggtagaat aattatgcat
    27481 atggaaagta ttagatactt cgatggtgag aaacacattg agtattcaaa cactcaagaa
    27541 gatgtagact ttattagttt tgaggaagat aaaatcacta aagttaattt taaagacgga
    27601 acgtgcttga agatagtttc gccttatatt gaatacaaat caaaatggga acaagatgat
    27661 tctgacgaac gagatcgctt tggttggtaa tctatggcag ttaaaaaaca atgtaatcat
    27721 gctggatgta aaacattgat tgattatagg cagaagtatt gtgggaagca taaagcaaag
    27781 caaacggcaa ttaagcgtga agaaagaaag caaagcgaag gtaaatattt tcaattctat
    27841 caaagtagaa catggcgaaa ggcttcatac ttgtatcggt taaatcatcc agtatgtgag
    27901 gattgcctag aagaaggctt gataaggaaa gctgatgttg tagatcacaa aattgaacta
    27961 aaagatgatt ggaatagacg gttagatgaa actaattttc gttctttatg ccatgcacac
    28021 cataattcca agacagccaa tgaaagacaa agacgagaaa agagtaccct ttgagttaag
    28081 ggggcatagt gtgaaactta ctgacaatcg atgcctactc attttggtac aaataaccgt
    28141 tgtgaaaagg cataagggta attacaaata acgattacac ttgtaatcac aagtgaaaaa
    28201 gtatataatg aaagtaggag atttattgaa aaatacaatt gttattactg ataaaacagg
    28261 gaaacagcgc accattgagt tacctcattt tggtcaagtg accattcaaa tgcagaacgg
    28321 aaaaatcatt tatatagata aattagataa agaaaaattc tgatcgaaaa acgaaggaat
    28381 gtgagcttaa ttgcttacgt tcctttttct tttgtctgaa aggaggacaa catgggacac
    28441 cctaaaatat tacacgatac aaaaggcaat atatcaagtg aagaaaaagc aatccgtgtg
    28501 gacgctagag aagaattgtt caagcagcaa ccattaataa atatcacgcc ccctgactgg
    28561 atggcagcga gcgctagaag tgaatggaat cgtatcgtac caacattaaa aaaagattat
    28621 ccattgagtg aagcagatta tggttcattg gtagcctatt gtttagcctt tgctcgaatg
    28681 aaaacagccg aagccgagat aagaaaatca ggtacgttta tcacatgcga aaacggagta
    28741 aagaaagcca atccagcggt tcgggttcaa tcacaagcta tgagtgattt gaaaaaacaa
    28801 gccacctcac taggtatgac cttagaatca cgatcaaaac tagctttgaa caaggttaaa
    28861 aatgatgaac ccgaagaccc gttcaaagag ttgatgaatt catgaatgat tacattgaga
    28921 aagtcctatc aggtaagctg attgcaccca agaaaattat ccaagcgtgt gagcgtcata
    28981 taagcgattt ggagcgttct aagtcagata gcttccctta tgtgttcgat gaagaacaag
    29041 ccaccaaagc gattaaattc attgagttgc taccatctac ggacggtaaa gcaatcaaga
    29101 tgttaggatt tcaaaaattc attctaggca gtctttatgg ctggcgtact aaagaaggga
    29161 attacaggcg attcaatcga gcgtttacca gtatgagccg taagaatggg aaaacgtata
    29221 tcgcaagtgg catggctgcc aatgcgttga ttatggaaca agaaccagca gaagcaaggc
    29281 aagtattgtt tgtaagtaac gctttgaaac aagctaaatt gggctatgat atgctgtcta
    29341 attcacttag aaacgtggtc aagtctagta agtttttaag accacaactg aaaattatga
    29401 actctaagat tcagcacttg ccctctaatt cgttcgctat ggcactggct agtgaaacca
    29461 gcacgctaga tgggtttgca ccaacaaccg caattcttga cgagtggcac gaagcaaaaa
    29521 ctcgtaaaac gtacaacgtc attaagtcag gaatgaccca acaaaagaac ggcttattgt
    29581 gtgttattag taccgctggg cttgatttaa acgttcctat gtacgaggaa tacttattgt
    29641 tagatcgtgt gctaaaaggc gaagaacaag ccgacaggta ctttatagcg atatgggaat
    29701 tggacgatcc cgaagaaatt cacgatcaag agaaatggat caaagccaat ccgatttttg
    29761 aaagtgaaga aatcaaaaaa gtaatgattc caaccattca agatgatgtg aaccttgctt
    29821 tgaaacaaaa taaccttaat tctgtattgg tgaaaaactt caatttatgg agacaagcga
    29881 gtgaggacag ctatatgatt gctgaagact ggcaggcaac cgaagtagaa ccacaagata
    29941 ttacaggcaa gcccgtttat atcggagtgg atttatctaa aacagatgat ttaactagcg
    30001 tttcatggat cgtaccgcta gataacggcg aactttattg tgattcacat agctttgtag
    30061 ccaccaaata tgggcttcaa gacaaagaaa agcgcgacgg tttgccttat cgagaactag
    30121 aaaaagctgg tgagtgttcc attactcaat tagaaagtgg aatcgtggac tatgaccaag
    30181 tatttcagtt tattcaagat ttgattcaag aaaatgattt ggaatgtatg gggatttgtt
    30241 atgacccgta taacgctaat tcgcttatca gtaaagctga aaaagccaac tacccaatgt
    30301 tagaagtaag acaaggaacg attactctaa acgttccgac ccgaactttt agagaacaag
    30361 tttatgaagg caacgttatt cacaataaaa atacgattct cacccatgca gtgaacaacg
    30421 ctattttaaa aacggataac aacggcattc agattaataa atcaaagaac agtaacaaaa
    30481 ttgatccaat agctgcatta atcaatgcct atgtgtttgc aatggattac ttcaccacaa
    30541 cggaaggagc gaaagcagac aatgaatttt atacaagtga agaattttct ttctaattac
    30601 attcataccg ttcttttact tcttggattg gtgtgtgtgt tggttgctat caccttacta
    30661 acaaatgtct actatggctt gttagcgctg ggcatagtgc ttattggggt agcggtcatg
    30721 ctaaatacag aacagaaggg aggttaaaag atggcatttt ttaaagcgag acaaaataca
    30781 acgggagatc ctttcctaca acatgtggta tcaatccaat cggatgatta caccaccagc
    30841 tttacaagcg ttcgtgcatt aagaaatagt gatgtgtttg cagccgttcg aattattgct
    30901 agtgatattg cttcaagtcc gattcaattg gtcaaaaaca atatgccaca agctgataat
    30961 gaactggtga agttactaaa cgagaaacct aattcagaaa tggatggttg gcatttaaag
    31021 tttgctttgg cggtcaatat gttgctaaac ggtaatagct ttgcagagat taaacgcaac
    31081 ggtgaaaagg tagaagaaat tcacttatta cctaactcaa gtgtaacggt tactcaatta
    31141 gataatggta cgttgtctta tcagattggt gataaaaaaa gacgtgtgaa gtctagcgat
    31201 attttgcact tcaaatattt cacccaagat ggtttaacag gattaccacc actttatgcg
    31261 ttacgtgatg aactgaaaat tcaacaagct ggcaaccgca cattgcacaa tttctttact
    31321 cgtggtgtca gtgggtcagg tattttgaag gttcataagt cagatttaga cggatcagca
    31381 aagaacgcaa ttcgtgaaaa gtttgaagaa gccaacggtt caagtagtgg agataatgct
    31441 cttagaacga tcattcttga tgaaacaatg gactacaaaa cattagaaat aaacaccgat
    31501 gttttgaagc ttatcaattc caatgattgg aacacaaaac aaattgccaa ggcgtttggt
    31561 gtaccgattg agcgtttagg cgttgaaaat gaacattcta gcaccgttca aagtaatctc
    31621 cagtatatcc aaagtacgct gattcattac tttaatgtgt ttgtgagtga attagatacg
    31681 aaacttgaaa ccaatatccg ctttaattcc gatcagttac tagagactga tcctgaaaca
    31741 aaagtaaaaa atgtattgga tcaggtcaaa gggtcacttc tcacgattaa tgaggggcgg
    31801 tcgaaaatgg ggctaccccc catggatggt ggcgatcgtt tactagcaag tttgaacttt
    31861 acgtatttag atacgttgga gaaatatcaa ttaaaagaac aggaaggagt tacaccagtt
    31921 gaataatgaa gaagaaaagg aaaaacggct gacagaagaa gctgagctaa cagccgattc
    31981 tcccaaagta gagaaagaaa atgaaaaaca accaacagac ggcaaaacta tttcaggcta
    32041 tgcgttgaaa ttcgggcaac cgtcaaaaga tttaggcggc tttgtagaag tgattacacc
    32101 cgaagcatta aaagaggtgg atttatcaaa tgtgttctta ttatatggac acgattattc
    32161 aaagccacta gctagtgtca aagcaggtac gttgaaattg aatgtcgatg atacaggatt
    32221 acattttgaa gcagagctaa ccgacacgac ctattcaaat gatgtgtatg agaatatctc
    32281 aaaaggggtt gttgattcta tgtcctttgg gttcgtgctt ggattagatt cattcgacaa
    32341 aaaagaagat ggcacaattg aacgatcaat agataaaatc aaagcactta atgaaattag
    32401 tgtcgtgacc gttcccgctt atgattcatc aaatgtccaa gtaaataagc gttcttacga
    32461 atcgtttatg agtaacaacc aagcaaaaca aacaaacaat agcttagaat ccacttctaa
    32521 agcacaaaag gagagtaata acatggaaaa aactttaatc gataacgaaa aaacagaatt
    32581 gcgtgggtat gaagaatata tccgttcaca aggcgaagtg cgtgatggag tcactactgt
    32641 aaatgcagcg gcagttgttc ccgaagaagt aatcggtgaa gtctttgatt tgaaacgttc
    32701 aaattataac ttagctcaat atgcaacagt aaaaacagta tcaaatggac aaggtaaata
    32761 tccagtagca actaaccaac aagcagtgtt agcaacaaaa gctgaacttg ctgaaattgg
    32821 tgatattgac gctgaaatgt ttacttcagt tgattataaa gtagaaactc gtgctggtaa
    32881 gattgcctta tcaaatgagg ttgtggaaga ttcagcagtg aatattgtac aagaggtcaa
    32941 agatcagtta gcgaaattgg tagaaaacac tgacaataag catatcatgg atttattaaa
    33001 aacattcact aagaaaacgg ctgctacgtt ggacgatttg aaacaactat acaatgtggc
    33061 attagaccca gcattaaata aaatggtaat tctaaaccaa agcggatatt accacctaga
    33121 tacattgaaa gattcagatg gacgttacat tttacaaccc gatgtgacag cacctagtgg
    33181 taaatcatta ttcggtatgc cagtagtatt gattgcagat acattgtttg ccaatcctaa
    33241 agctggaaca ttccctatga ttatggggga tattgcacaa tctatctttg ttgctcgtag
    33301 aaatcaagta acgactcaat gggaaaaatt cgattactac tcacaaggac ttgcagtgat
    33361 cgttcgcaac gattataaga aaattgatca aaatgcttca gtgtatattg agtttacgcc
    33421 agttgtaaca ccaaaagtat agaaaaatat tgggcggcgg tttatcccac tgcctttttt
    33481 tcattaggag agataaaatg gtaattttgg atagcataaa aaaaagtatg cggatcgatc
    33541 acactattga tgatgacttt attcaacaat tgattgatac agcaggcgaa tatataaaaa
    33601 gtgctattga tagtagcgca acggataaag atatggataa ttatcagcaa tttgatttgg
    33661 cggtgtcatt acttactcaa cattggtatt tgaaccgtca agaagccagc agcgaacgga
    33721 taccagtaac ggtacaagca ttagtacaac aaatgagagg tgcttattat gccaatcatt
    33781 aagaatgtaa atgaattgac tgagagagtc aagtttaaaa agacaaaacg ggtaaaagat
    33841 gaagatgggc agatggtgga tagtgaagaa actgtatttg aatgttgggc taatgtgcgt
    33901 tcacaaatgc taaaagacgt gcttgctagt gtaggtacca ttcttgaagg aacgttgacg
    33961 tttattattc gatacgatca agattatgaa ctaacaaacg atatgaaagt agcttggaaa
    34021 aacaagagtt ataaaattat ttcaatcaat gaaggaacgg cgtttaaaga ttatacaacg
    34081 atcatagcta aacagatttc ttagaatgat tacacttgta aacgttgtgg gtatttagta
    34141 taattaaggt agtaaatgaa gggttagctg cctgaatttt gcaagactta gctagtcgaa
    34201 atctattgtt ggactgaaaa ttgtaggtgt ggttgcaaac atgctggact aagaaagatg
    34261 atagatgatg aacgttcaat tttaatacag gcatgctagg actgattgga tggttttggc
    34321 aagctgattg tgtagaaatc aaagaacacg tctgttgtgg acgtgttttt tttgttataa
    34381 ttcaaaagag gtgatttaat ggacaaagca gagtttacaa atttttattg gaagtattat
    34441 ctacatttag aaaatgagtt tattaatacc acagattttg tgatgctcga tgagaataat
    34501 ttcaaaacat tctctattga atatcaaaaa ctactactag cgattggttc ggagtgtgag
    34561 attattttca aagaactttg cggatttgat agcagtagca ataaaagcat aactgatttt
    34621 aaagctgtta ttaaatctag cgaattaatg tgtttggata atggtgttag ggttatgaat
    34681 tctttaacat tgacttcact aaaacctttt ggagatgggt ggcctgaaga tacaccagat
    34741 tggtggaaaa tatataacag agtaaaacat ggtcgttctt caaattataa ggaagcaaat
    34801 ttggaaaatg tgttgtatgc tttagcaagt ctatatttat tagaggaata tttgcataag
    34861 aaagtaatac tagaaggtga agtagacttt ataagtccag agtcaaatct atttacgtta
    34921 tcttgggaaa gaaaacattc gtcgatgcaa aaagtgacgt ttgaaaaagt ggattcaaat
    34981 tatgtagctc cactcattga ttttaaagaa caagaagaaa tttaaaaacc cccacggctt
    35041 attgaagttt ttgtatgcca tattgtatgc catttggttt aaatcgcttg aaaaatagtg
    35101 atagataact ctaattcatt tagtcataaa cgctgttttg ataaccttta tagttctttg
    35161 atatgggttt ctcattcatg gcggaagaag aagaatagaa caaaagaatg aattaataag
    35221 atataaaaaa agggattgtg acaaacgtct tgtcacaatc cctttttcca aataaacgat
    35281 gttcaatcag ctgcccctcg gcattcgctc gaaaaacggc gaaatatgaa gaactatttt
    35341 gccatttgtt tctctaataa tcaggtcaaa acgttgactt cacagtctct tccttaaacg
    35401 gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat gagaagctgt
    35461 tttttgaaat tgttccttgt gactcggagc tgaacggcag gctcacgacc tctttcttaa
    35521 acggtgttca aaagcttgca tctgcggtaa taagttcaac caaacgaaaa ttatgaggag
    35581 ctatttttgt ttggctgttc ttattacttg atgcaggaca gctttttcac aacctctttt
    35641 cgtttagcac taaatttcct taaaaagtag aaaagctttc gaagcctcgt ttgtttcttt
    35701 tactgtataa taaaagaaaa gagtaacaat cgctaaaaga tataaacaag agaaaggaaa
    35761 tacaagatga ttggtctgat ttattttgtg gtgatcgttc tggcgaacac agttggcgct
    35821 atttccggga tgggtggagg cgtgttgatc aaaccgattc ttgatcttat cggcgcccat
    35881 tctgttgcag ggatttcttt ttactcaaca gttgcggtat tcacgatgtc cattgtttcg
    35941 actgtgcgac aagtatcaag cgggaaatca ctgaattggc agattgtcgg ttgggtatct
    36001 agtggagctg ttgttggagg agtagtcggc aacattgtat tcgaagtttt tttacagtta
    36061 tttgaaaacg agaagcatgt gcagctgatc caaatttttt tgacggtatt gaccttggtt
    36121 tttgcgttct tctacaccaa gcatcatcag ccaaaatttc atttgacgtc atggacttgg
    36181 taccttatat gtgggggggt tctgggcttt ttagctagtt ttttaggtat tggtggtgga
    36241 ccagtcaatg tttctttgtt gatgctgatg tttgcattgc caataaaaga agcaacacta
    36301 tattctctat ctacgatttt cttttctcaa ctggcaaaat tggtaacgat tgctttaaca
    36361 agtagcttta tgcgctttga tttatctatg ttgttttatg ttatccccgc tgctgttatt
    36421 ggaggtttgt ggggagcaag atttagcagg gttttgtctc caaaaaaagt gacctttatt
    36481 tttcaagtaa ttgtcctcgt ggttcttttg gtcaattgtt acaatgcctt tgtcatctta
    36541 caaacattag gagaatctag actaacgcaa gtcaaaatca ctgaaacata ttgttctaaa
    36601 tgaaaaaaag agtatactat gataaaaaaa ttcattttaa aaaatcagaa attggctggt
    36661 gatttggatg ttacgggaaa tgcgtttaga agatgcagaa gcactacgtg aaatcaatgc
    36721 ggatcaatta gggtatgata taccattaac cgttacggtg agacaaatga agaaactgct
    36781 gaaggagcca gagaaaaatt ttttcttggt ttatgaagat cctacttcta aaaaagcagc
    36841 tggctatgta caagcggagt cctatgaatc gatttttagc gatccaatgt tcaatattat
    36901 ggcacttgct gtgtctaaat atgctgaaaa aagaggcatc ggaaaggctt tgatgactgg
    36961 cgtagaagaa gaagcgaaaa aacgaggaat aacgacaata aggcttaatt ctgcagaata
    37021 cagagtagaa gcacaccaat tttatgaaca catcggttat cattccgata aaatgcaaaa
    37081 aagatttttg aaaatcctgt aaatctttat caaaaaaata cccgatcacc aagccgatac
    37141 ttgatgatca ggtatttttg tttttttgac taagaaagta attgcatcaa gaaaccagag
    37201 atgatcaaaa cgatggcacc accaagtcga ttgcccattt gagcaaaagc aataagttcc
    37261 atccgattag ctgcagataa gacggctaca tttcctgttc cgcccatcga gttgttgcat
    37321 aagccagcag taatagttga ttcaattgga tataaaccaa acaaacgacc gacaaatcct
    37381 gaaacaactg aaatcgcgat aacacttgtc agacataaga caacaaattg ccatgtcaaa
    37441 gcagaagcta atacattcag attcagcaac gcaataccga taccggcaag aacagctgct
    37501 gtcaagtttt tgacaatcaa gttattgaac atgatagctg catcttcata atactctggt
    37561 aataggttgg cgattttaca gatgacaacg ataataatca taaatgcgta agcatggact
    37621 ttaggaacaa aatagttacc aatttgtcct aagatgaaga aagtcaatga taccatcaaa
    37681 ccaacaccta actgtggaat ggaaggtttc acagttcgag gttttccatc gccaagatcg
    37741 cctttttcca ttaatttacc attgccgttg aattttggca ttgattgtcc agcacgagca
    37801 actaatgctg caccgatgat agctaagaca tttgtcattg ctgtcgcagg aatcaggcgg
    37861 gaaatgatag aagaagcatc cgtacctaaa acatttgcat aaatcgttga taaaggaacg
    37921 gctccggctc caacaccacc agccatcgca ggtaatgaga tgtataaaac ggaatttgca
    37981 aaaccatttc cgataagcat gcccacgagt cctacggcaa aaaaggagac gaccattgaa
    38041 ataagtgcaa cgggaataaa acgaacagaa gctttcatca atagattacg gttcatacca
    38101 aggatgctac cagtaatcaa ggcagcaata taaaagtccc aaaagcccat attgctgaca
    38161 aagttttctg tggatttcac tacatattca ggtaagatcc caaatgtagc aatcgcagca
    38221 gaagcgaaga tcgcaaaaac ggaaccacca cccaaataac ttttgacgat agggattttt
    38281 gtcccgataa aatgaaataa attaccgaaa ataaccaaaa ctgcgattgg tccaatcata
    38341 ttcgtcggta atttccctaa agccattgca atgatcagga caaggaccat gatcaaataa
    38401 agtggcaaac ttacgccggt gatttttgtg gaccaaaaac cttctttttt cttttcctca
    38461 actgcagttg cagttgttgt tttttgtgcc atttttacag atcctttctt attctgtatc
    38521 atatgaaaaa agccaaagaa aagcgacaaa agagcaggag ttggctggcc gctgttttgc
    38581 cgcagtcgct tttttctttt tagacgtcat acaaagtttc tgtatgttct tttactataa
    38641 cgatcttaat cttctaaaga tttatattca ggaacccatt tagcagattc aactgcttct
    38701 ttgatatccg tgatttcttc acgattcaag ttttgtgcga caactgattt tgcgacagtt
    38761 tcagcaatcg tttgagaaaa ttcagtgatt tttgctactg gaggcaagat agctgctcct
    38821 ggttttgtta catcaacgat tccgcctaat gctcgactag cttgagaaat gatttcagca
    38881 tttactcgtg tagctgttga agcaatcaaa ccaagtccta aacctgggta catcaaagca
    38941 ttatttgctt gaccgatttg gtaagttaca ccattatatt caacatcagc agcagggata
    39001 cctgttccaa ctaatgcttt tccgtccgtc cattctatta aatcttttgc ttttgcttct
    39061 gccaattttg ttggattaga caaaggcatg atgatcggac gtggtgtatg agcagccatt
    39121 tctttcacga tttcttcagt gaatgctcca ggttgggtag aagtaccaat catgattgtc
    39181 ggatggatcg cttttacaac tgcttctaag tttgtcaatt catcagcatt agtgaaatct
    39241 gagcgtttgc gagcgaatgg gatttgacca ggagtcaatc cttctgtatc ttcaaacaat
    39301 aaaccttgtt tatctacttg atagaaatgt tggcgtgctt cttcttcagg tacaccttga
    39361 cggatcatct catctaaaag gatgtttgcg atacccacac cagcagtacc agcaccaaat
    39421 gtcaaaatta tttgatcttt caattgttca ccggatatat tcaatccgcc taatacacct
    39481 gctaggacaa caattcctgt accttggata tcgtcgttga aagtagtgat ttgatcttcg
    39541 tatttttcta agatcgctgc agcatttcct cgtccaaaat cttcccaatg caataacaat
    39601 tctgggaata attcggtagc tgattgaacg aattgatcga tgaattcata gtaagtttcg
    39661 ccttctacac gagcatgacg attgcctaag tataagggat tattcaataa ttcttcatta
    39721 ttagtaccag cgtcgatcga tacaggcaaa acttgtgctg gattaatacc agcagcagca
    39781 gtatagacca tcaatttgcc gatagcgatg tcaacaccgt tcacacccca gtcgcccata
    39841 cctaagattc cttctgcatc agtcacaaca atcaaacgaa tgtctcgtcc atctgccgcg
    39901 ttcttcaaac ttgctttgat gttttctggt tcgtcgattg aaagaaatgc agcatcttgc
    39961 ggtttcaaga aaatttcgtt gtattgttcg attgaatccg caacgacagg atcataaacg
    40021 acaggcatga attcaactaa atgttcgccc atcaatttat aaaacaatgt ccgattcgta
    40081 ttgaatagat tcattaagaa gatacgtttt tccaaatctg tttgtttgct taagtattga
    40141 ccataagctt gaacagattg ttgttccagt gtttggacag tacttggaag cataccagtg
    40201 attccatatt ttgcccgttc ttcttttgta aaagctgttc ctttatttag aaaaggatta
    40261 tttaataagt ttaaccctgt aagcatgaat gattcctcct aagttttaat acaaacgaag
    40321 tatagaagtc agatgatgat atagtcaaaa agagcaggta tgataaattt tatttatatg
    40381 taatatagcc aaaagaaatc aaaatagcag tatttgttct ttttatatcg acaatccttg
    40441 cttgaatact atgcgtatct cttatatgct agagaaagaa aagtagaaga ataagggata
    40501 gatggaatgg ataaatagga tttctgagga aaaaagcaca tgatagcgtt gataggagtc
    40561 acctatgtca ggtgataaaa atacataagt agaaaattaa gaggaggaag agaaaatgaa
    40621 agaagttcaa ttgattagaa aaagcgaact atcagaaggc ggttgcaatg catgtggcgt
    40681 agtagaagcg acaagctata cattaaaatt agattccaat caagcaataa tctctgaact
    40741 gacagtaggc ggtcttgtgg acagtctggc gcttgctgaa ggttttactg gagaagatat
    40801 ttatgagatg ttttcagaag tccgtcagtt aaaaaaagga gaaaaatgca tagaggttca
    40861 tcatgagagc ccgaatgtga ggttcaaacg tggtgataat gagatgatct tcaagaatca
    40921 tgtgtctgat cacactgaac tatatgaaat cgtgaatcaa atactgtctg ggatttttga
    40981 attaggacct tatgagttca aggaagaaaa cggtaatcca aaattaaatg aagaatggca
    41041 agaaacgatt gaaacacaaa gaaacaatcc acacttattt caatagtctt ccacagtatt
    41101 tcgtaaaaat gttgatgaaa aagaaacacc gtgaatcaga ggtcgtgaaa aacctgccct
    41161 gcatcaagta ataagaacag ccaaacaaaa atagctcctc ctatttttcg tttggttggg
    41221 cttattaccg cagatgcaag tttttgaaca ccgtttaagg aagagactgt gaagtcaacg
    41281 ttctgacctg agtattagag agacaaatgg caaaatagtt cctcatattt tgccattttt
    41341 tgagctaata ccgagggtca gctgattgaa caccgtttta tcgagaggtt gtgaaaaagt
    41401 cgcttagttt cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa
    41461 atttgactta ataccgagaa aatggctttt gaacaccgtt tattcaaaaa aagggacttt
    41521 gacactactt ttgtcaaagt cccatcggtt ttttatctat ttttattaca atcatttctt
    41581 ccagagtagt gacatctgga atggctgaaa tgtaaacaga ttatttgcct gtatcaatgt
    41641 cgaagagtaa tataaaaagt gtaaacgcta tcatattgtt catcattcaa attttataga
    41701 gagaaggcat tgagatggaa aaaacatatc aagcaggtac aaatgaagga atagtagatt
    41761 ttatcaatat ggaagattta gaaatcgcgg cttcacaagt gattccagct ggtggttatg
    41821 gttacatcag cagtggtgct ggcgacttat ttacttatca agaaaatgaa cgggcattca
    41881 atcatcgttt gattattcct catgtattaa gagatgtaga attacccgat acaactacac
    41941 attttgacga agaaatgctg actgcaccaa tcatcatggc accagttgct gctcatggat
    42001 tagctcatgt gaaggcggag aaagcttctg caaaaggtgt agcagatttt gggacgatct
    42061 atacagcaag ttcttacgct tcttgtactt tagaagagat aagagaagca ggcggggaga
    42121 aagcaccgca atggtttcaa ttttatatga gcaaagataa tggaatcaat ttggatattc
    42181 ttgaagtggc caagcgtaat ggagcaaaag caatcgtatt gacagcggat gcaacagttg
    42241 gcggaaaccg tgaaacagac cgcagaaacg ggtttacctt cccgctgcca atgccgatcg
    42301 ttcaggctta tcaatcagga gtaggccaaa cgatggatgc tgtatataaa tcttccaaac
    42361 aaaaacttag tccaaaagat gtagaattta tcgctgctca ttctgatttg ccagtctacg
    42421 tgaaaggtgt tcaatcagaa gaagatgtct atcgatcatt agaatctggt gctggtggaa
    42481 tttgggtatc taaccatggt ggccgtcaat tagatggggg gcctgctgcg tttgattcgt
    42541 tgcaatatgt ggcagaagca gtagataaac gtgtaccaat cgtgtttgac agcggtgtac
    42601 gacgtggaca acatgttttc aaagcaatcg catcaggtgc cgatcttgtt gctattggca
    42661 gacccgttat ttatggattg tctttaggag gaagtacagg agtccatcaa gtgtttgatt
    42721 tctttaaaac agaattggaa atggtcatgc aattagctgg aacacaaaca gtagaagata
    42781 tcaaaaaaat aaaattgcgt gagaatcgtt ttatttaaga aataaatgac gaaaaaaata
    42841 ggagtgcggc agatgatgcc gtactcctat ttttatagtt caaggatgtc actaatagaa
    42901 taatttgaaa cgaaaaaata aaattgaaat attttttcat acttaataaa aaaggaagaa
    42961 tattcatgta aacgatttta ttgttttttt ctcttttata caaaaagggt cataatttca
    43021 agtaagcgga tgaattcatg aggatttttt gcatactgtc tctactatac ttaggtcact
    43081 aagaaaaagg agtgatttat tatgaaaaag aacatgattg ggacattatt actttcaaca
    43141 cttcttctag gcggcttggc aacaccagct tttgctgagg gtcaagcgac ttcaaaagga
    43201 gatattacct ttactgaacc aacaaatacc gttgagcctc ttaaccctac tgatccttca
    43261 aaaccagtag agccagcaga tccggaaaat ccagcaactg gccagacagg ttctttaaca
    43321 ttggatgtag ttcctgaatt gccatttggt acacacgaga ttgaaagcgg aacaaaaacg
    43381 tatcaagtag acgcttcaaa aaacgataca ccttatctcc aagtatcaga tcgtcgaggt
    43441 gtaggtgcag atggccaagc acaagggtgg aacgtgacag tttcggtttc agattttgta
    43501 aacggttcac aagttttgca aggcgctgaa ttagattttg gaacatccac tgttaaaagt
    43561 acgtcagata acgaatccac tggaccaact agtcaaactg taactgggtt gagtaaagca
    43621 agtgcagcga caccaatatt tacagcagca aaagatcaag gtctgggaac atggctttct
    43681 gtttatgatc cagcaaatat cacactgaaa gtgccgaaag cagcagctgg aacattcacg
    43741 gctgatttga cttggaacct cgtggctggc ccagtagcat agagtatgaa ataaattcaa
    43801 caaactgcgg tgaaaatact ataggtgaag gattttttac cgcagttgtt gttgaaagga
    43861 tgtggtggac aatgaatcaa agtaaacgac tgtttgtttc gtttttttct attttaagtc
    43921 tatttttcat ttttccgtca atcagccaag caaaggattc agcaggagac tttggaatca
    43981 aaccggtatt tccagagaac caaatagata aagcaatcgg ttattttgat ttattagtgg
    44041 caccggaaca aaatcagaca ctagaagtaa ttatcagcaa ttcttcagat gaagaacgaa
    44101 catttgaggt ctctgtcaat ccggcggtaa cgagtgatgg tggaacgatc gattatagtc
    44161 aaaaaaaccc aacgttagat gagacattgc cgtttgatgt ccgtgacgtt ttgctcattg
    44221 cgaaaaagga aatcaatgta tcagcacatg cagaaacaac tatacctata gaagtgaaaa
    44281 tcccagcaaa aagctttaag ggacgtgtat tagcgggtat tcatgtttca cctaaagaag
    44341 aagctgaaac agaaaatgct acagaaggag cacaaatcaa aaatcgtatt gcttataatc
    44401 tcgcagtcgt tttacaagaa agtcaagaga cgatagaacc ggatctgaaa cttttatcag
    44461 gagatttgga cgaggtcaac gcaaagccaa ctgttcagct tcgtttccaa aatcctcagc
    44521 ctaggattat cagcaatttg atatttacga gcaagatctt ttatgaaaat cagctttata
    44581 ttgaaaatac gtctaatgaa tttttagttg caccaaattc gaattttcac ttgaatcttg
    44641 atttagctgg tgataaagca aaagccggcg attaccgcgc agaaatcata gcaaaatcag
    44701 gcgacagtaa tgaatggcga tttacacaaa actttacgat caaaaaagaa aaagcacaaa
    44761 aagtaaatga aaattccgtt tttgcagtac aagaacaatc tttcccatgg ctttatgcag
    44821 gattggttgc tgcagttcta gtgttatggt tgattttgct gtttttgtgg gtccacaaga
    44881 aaaagaaaaa aggagaaaca acatgatgag gtgatttcgt tgaaaacatc gatcttattg
    44941 ggagggatta ttgcaagttt gctgttcttc agctggcaag agccagtcca agcagatacc
    45001 aaaagttcag gtacgattac attttatgat ctaagtccag ttccgcatcc aagtggttca
    45061 gtcaatggcg catcaaaaca gcagacacag ctaccgattt ataaagaatc taatcaacat
    45121 ggcgtattcc cggagacgaa tgaagaaaag atccgttttc tttatttgat cattggtata
    45181 gaattatggc ttcttgcgtg gttgttgtta tggagaagaa aggaaaagga ggatgaacat
    45241 gttgctacaa aataaatttt cattttttcg ctccttcttt tttacttcgc tttttgtttt
    45301 aagtatattt atcttttcac cttcggcaga agctgttgga gcaacgcctc ctgccatttc
    45361 ttatgatcca tacacgtatg aaaatatcgt acctccaaat ggtggacgta gtgcagtcaa
    45421 tggcgggaag cttgtccaac taactggggc taaccaattg cctaaattga ctgctactta
    45481 tttgaacgat ggttcaaatg atccttggaa aggtggcacg gtccgttttc attgggaaag
    45541 ccatgtgaaa ctaacaaatg tacttgattt ggtgaatatc actgcacaag gatttgcatt
    45601 tgtggcgatc atcaatttgc cggaacatgt atcaagcagt gatgtattaa aagcaattga
    45661 ctggaacaac gcctacttgt atattgccgg tgcccccatc aaggttacta gcggtagttt
    45721 attatcagca ggaagccata ccttgcgttt tgggatgggg tcgtgggata caaatactct
    45781 attggcagat attattgcta ttattacgcg aggcgaattc aacgtggacg atatcccgct
    45841 tcaatttgat gttacagcta atgtcgcgaa gatgacagaa aacggagata aatatgatac
    45901 gagtccaaac aaaattttga ccaagggtaa attacaacct tctatgtcta aaaaggccgt
    45961 tttttctgtt gatttttatg attcgaataa tattatccaa gatcgtatgt tcaattcgat
    46021 tttagctcca gctgcaggta gattttatcc taaattaact ggcggaaact tgaatccagg
    46081 agcatatgca ttttctgcaa gtgcagagat aaatacgtgg aatagttaca tctcaacaag
    46141 tgattcaaca ggaaaatata atacatttgc tgataccaca gaatacgtgg atggaaataa
    46201 ccagaacctt ccaggctcta ccaatagtcg gacattgacg atggggctga ctgaaggacg
    46261 ttttgatcag ttgccattta gtcgctttga tcgcgtagtc aactatttta caggaaaaaa
    46321 cgttacacaa ggagcaatac tgactcatac tccagcaagc acaagtggat tgaatcagac
    46381 agccaatatc gtgtacagtg ggaaagatgc gcaaggcgga ttgctttctc ctgttgcttt
    46441 aaaggtattg gagcagtaca agctagacgg aacggtttta ccaacaaact taacagccga
    46501 tagtcagtgg ggaaagctcc tttcttctgc atcgtaccaa gtcacggcca attggtcagc
    46561 aactgaacta aaaaagggtt cgatccatta caggctttat tcgaaaggaa cccaaaaatt
    46621 agcgacagga tggacagatc aacttttcca aacgatccaa tcaaataacg ggggtgtaaa
    46681 tacagctact tctacactac ctgcattggc ttcagggcaa tattattttg attatcgctt
    46741 ggtggacgat gtacttacta acatgtatcc gtcttttgcg tacaaatggc agtctgaaca
    46801 agctggaatc accactcttc ctcaaataac agtggctaat tttccatctg tgagtgcaga
    46861 tagtcagcta aaaaacctta gcagacaacc tgagacagga gatcccctgt ctgctctatc
    46921 aggagatacg attcaagaaa atgtgacatt cacgttaaca aaatctgggg atgcgataac
    46981 cgacaaaaaa atcacgatct cacttcctga aaatactact tatatcaatg gttccttaaa
    47041 attaaatggt acaactatcg cagataccgg cattcaacaa ggagtttctg tcccagcaga
    47101 tctattgagc aaaataggag ataccattca tcttacttac aactatcaat taaatactgt
    47161 agatacttct gtacaatccg tcagcatact gacaaaggca gctgtacttt ccagcaatat
    47221 tacattagca gatggtgcta agcttcctaa cccagttgtc caaacatctg ctaaaacaat
    47281 tcttgtcccc aaacaagaat taacattagt taatgtacca gatgatttta catttggtaa
    47341 cgatctcccc aaaccgttga agacaagtta ttatgaagca aaaggcgatt tttcttttga
    47401 tgtgcgggat actcggcttc caagcacgtc tccttggcaa ctgacaggga cattgacttc
    47461 tttatttaag aatgatcaag gtcaagaatt aagcggaaca aaattatact tcaatcattc
    47521 tggatcaaaa caattgattc agcaaggtca aaacacgttg atttatgaga gtgatggaac
    47581 agctaaagga gaggttctcg ttgactttcc cgataccgat ggtttactct tagaggtaaa
    47641 tagcagtacg aatgctcaac ctggcgcaac gtatcaaggc atggtcacat gggaactgac
    47701 agctgggcca accagctaag tgattagaat ttgtatggat ctgtgataac tgtcacagat
    47761 cctctttttc aaggatgaga aggaaacttc tgctgttaaa atcagaaatg cttggaggag
    47821 tggacttgga acttttcagt ttgcttgaaa aaaatgaaca acggcaaatc aaacttttcc
    47881 aacttttatt agaggaaaaa ggagagattt ccgttaataa cgtacttacc cgcttatcag
    47941 ttgatcgggc taccttgaaa gaagatctgt tttatttaca agctaacttg gaaaatatca
    48001 aacaattgga aattgttatc caagaaggga atattttatt aatcagacat ggaaatatag
    48061 cagcagtcga tgtttattat cattgctact tgcgctattc tacaaaatat cagatacttc
    48121 tttatctgtt ggaaaatggc tcatttgatc ggcagaaact tgtcatggaa cttaatatca
    48181 gttcggctac tttgtctcgc agagtgaagg aattaaatga ttctttaaat gagtttcatc
    48241 tgaaaataaa aagcgggcgg ctgaccggtc cagaaagtca aatttgttat ttttatttcc
    48301 aattattttg gtttggacgt ccttatcttg aaaacaaaaa agaatacagt gatttatcag
    48361 gaaacacttt tttagatctg ctgcaaaaag agtttagttt tactattaca gaagaaggac
    48421 gattgaaatt tgaaatatgg ctttccatta tgaagaagcg aatgcgctgt acgaaaaaat
    48481 ccaaaccaga ttatagcaat cttcctgttg gattgtttca aacgacacaa tttttattgg
    48541 acctccatac atttttgacc cgttacttct ttcaatatgc ctttccttgg aatcaaaatg
    48601 aaacgttggt tttttatctt ttcatgatca gtaactttac attagataca cataactcgc
    48661 atgtccagga gtttttgata agcgaaaaat acaaagacga cgtagtagct caattgaatc
    48721 gaacgtttaa acaatcgata gaagaatatt tctcttttta tgtttttcca gaagagattt
    48781 cgcaaaagat tgcgttgaca gtgatgcaaa atcacgctca ttttgcctat tttagaggat
    48841 ggatgaatat ttttggccaa gaaggattaa aacagcggtt aactgaagta gaagataaac
    48901 aattcctggt tttatgtgaa agattggtca gacaaacatt tgctattgtt gattttactg
    48961 aagtagacga ggaaaatgcc cgctttgaat tatttgctcg ctatgcatct attttgcgga
    49021 cgctgatcaa gcagttagaa ttacgtctgc aaattgctta tgatcttcct tatgaaaggc
    49081 taatggcgga tatcgtgaaa gaaatcatcc aggaacaatt gctgaatacg atcaaatatg
    49141 atttagtcga atacgagaaa gaaaagcagt atgatatcat tttgactagc caattgaaag
    49201 agtacccgtc acagaagtcc gctaaagttt ttgtattcac tagcaacgaa tataattatg
    49261 atttccccta tttgaaccaa tttttaaaag aatgttattt agaaaaattg aatttaagga
    49321 tgaataaaac atgaaaatcg tgatcattgg tgcttcccat gcaggcatca cagctgccct
    49381 aaatctaaga aaacttcaac cgaaagcaga agttttactg atcgatgaag atcataaaga
    49441 tggactaggc tatgtttcaa atggaatcaa cctttattta aaaggaaaga tacgtagttt
    49501 agctgaagtt gcccataaca tgcggactct tcaagaaagt ggggcaaaac tgatcaccga
    49561 atggagagta actgaacttg atccagacaa acatcagctc atcctcgcat ccaaagaagg
    49621 aaaaaacgag accataacct atgataaatt aatcgtagca acaggttcct ctcctgtcac
    49681 cttgtataaa caaattgaag ctgaaaatgt ctacacctat aaaaatctag tgcaatctaa
    49741 gcaagtactt gccgctttaa aagaagcaaa agaagtagtg atcttcggtg ctggttatat
    49801 tggattggaa ttagcagatg ctttgagaaa taaaggatac attattcatc tagttgatta
    49861 tatgccgaat gttttaacaa gatatttcga taaggatatg atcaacagtt ttcaaaatca
    49921 gctgcaaact aagcaaatca atttttatcc aaatgaattc ttgatcgatt ggaaaaaatc
    49981 agaagagaaa gtagtatccg tacaacttct atctcaagca ataaaggcag atatggtcat
    50041 tttttctgcc caaactcgtc ctaatacgac attgttaaaa gaaaaagtgg ctttgtatga
    50101 ggatgagact gtgatagtca atgaatatct gcagacaagt gatccggaca tctatgcgat
    50161 tggagatatc gtcccagtca gttttgacaa aaataaacgg catctctttt tacctttagt
    50221 tactcgagct gtacatatgg caagagcagt agcgctaact ttgagtggtc agccaaccgc
    50281 ttacgacctc agacaaaaga taacagcagc agtcattata gactactttt taggaactgt
    50341 agggctgaca gaagatgaag cgccattctt ggaacaaaat accggttcgt gttcaggaga
    50401 atttgatcta tttccacaat acgatgaaga aaacaaaaca gtaaatgcaa agctgatcta
    50461 ccatccggat acattagaaa taattggcgg acagctgata agccaagaat tcttattatc
    50521 agatttgaac ctgcttgcgg atatcgtgaa acacaaaact acgattccac agctagcagt
    50581 tgaggatttt ggatttctgt ctgaacacac ctctcgtttt cactacctca atgagttagc
    50641 ttttaaagta ctagctaaga gagcaaatag caatagagta gataaaagac tgtgagaaat
    50701 atcacggtct tttattgtgt ggggatataa taaatattaa tcaatcgaga ataaaaaatt
    50761 catataatga aatagcggaa gaattttttg agcataatat tcgccaaaaa tttatcaagt
    50821 gataaaattg ttgtataaaa tgattatttc aggaggagga gttaaatgtt tttagcatta
    50881 aatgaaatta tgcattcaaa gttacgttat gcgttagttg caggggtgat gtttttgatc
    50941 gcctacctgg tatttttttt gactgggtta gcttatggct tagctcaaga taatcgaaca
    51001 gcagtcgaca agtgggaggc agattcgatt gtgctttcga aagatgcaaa ttcaaatcta
    51061 gggatgtcca tgattactaa gaagatagca gaagaagtcg aaggtgggaa agtggcgtat
    51121 cttgcccaga cacctggagt cgtgactagt aaagacagta cagaagaagg aaaaatcaat
    51181 gttagcttct tcggtatcga taaaaatcaa ttcatcatgc ccaatcttgt tgaaggaaaa
    51241 gcttttgata acgatgatga ggcagtaggc gatattagtt tgaaagaaga atatggtcta
    51301 gccgtaggag atacagttaa gttatctggt agtgacaaga cgtttaaact aactggcttt
    51361 acggatcatg ccaaattcaa tgtctcacca gttctctata caaccatcaa tgcttaccaa
    51421 gagatccgct tcgaaaaaga agatacaagt gaaaatgcac ggattaacgc aatagttgtc
    51481 agaggtaaaa tcagtaattt acctgaagat ttagaacaga tcaaaatttc taaattcatc
    51541 aatgaattac ctggatataa tgcgcaagta ttgacttttg gatttatgat cggatttttg
    51601 atcgttattg cggctattgt gatcgggatt ttcatttatg tactgacgat gcaaaagatt
    51661 aatatctttg gtgtaatgaa agcacaaggg atcacaggag gatttattgc gcgttctgta
    51721 gtggcacaaa cattcatttt atcatttgtt ggtattcttc ttggtctatt aggaacagtg
    51781 ggaacatccc ttgttctacc tgatgcggtt ccattccaaa gcaattggct gttttttggc
    51841 gtcattagct tgttgatgct ggtagtagct gtgttaggcg cactattttc tgttcggaca
    51901 atcgtaaaaa tcgatccgtt gaaggcaatt ggataagaag gaggaagagc atgaaagcaa
    51961 tagaatttaa agaagtagaa aaaagtttcc aagatggcga ccaagtagtt aaagcattga
    52021 aagaaacaac catgagtatc gataaagggg aatttgttgc aatcatcggt ccttctggtt
    52081 caggtaaaag tacttttttg actttggcag gcggattgca gacgcctagc agtggctctg
    52141 tatttatcaa tgatcaagaa ttcagtaatc aaaaagaaag tgaacgcgtt aaactacgtt
    52201 ttaaagaaat tggctttatt ttgcaagctt ccaatctggt tccttttctg acagtaaaaa
    52261 agcagttatt attagtagat aagatcaaac atgaacatcg tcaaaaagaa gcaaaagaat
    52321 tatttgagca gcttggcgtg gataagttga tcaacaagta tccagaagaa ctatctggtg
    52381 gagaacggca aagggtcgca atcgctcgtg cattgtacaa tgatccgtcc attattctag
    52441 cagatgaacc aactgctagt ttggattcag aaaaggcacg agaagtagtc gatatcttgg
    52501 caaaagaatc aaaagacaaa aataaagcaa cgatcatggt tactcacgat acacggctga
    52561 ttgacaaatg cgatagaata tttatgatgg aagatggtgt attgaaagaa aaagaataac
    52621 caaaaagcag gtggaaaaat ggtccatcga tacaacaaag atacacagca aaaaattttg
    52681 aaagaagcga ctgacttgtt tatgtccaag ggatatctcg gcacttcaac aagagagatc
    52741 gcacaaaaag ttgggatcac ccaacccaat ctctatcatt atttcggtga taaagaaaaa
    52801 ctatatacgg cagttttaga aaaccactta aaagatgttg gaaaagcttt gagagaaatc
    52861 gttcaaacaa gcgaaacggg atttcaagta accttgacaa aaatggcgca gtttttgatt
    52921 gagacacatc tggtcgattt gtttctgatg cttcacgatc ttgaaagcaa tctttcaaag
    52981 gaaacaagag atcatctttt ctttctatgg aagaaaaatt atcgtgaacc ttttgaagaa
    53041 atcttttcag caaaccaatc tgtgctaaga aatgggattt caaaagaaat cgcagcaagg
    53101 cattttttct tagtgttagc accttacatc actcggtcga aaagacctgt ggaagaaccg
    53161 ctaaatgtgg cgcaattgat cgatttatat ttgaatggtg tattaggaga agcgtaaagc
    53221 tgttatatag ggagaaaaat agttaggtga agaagcaaga tatgacgaag atcgttatat
    53281 cttgtttttt ttatataggt agtttttcat aaatacaaat ttgttattct ctcatgatta
    53341 tcagggtata tttttattta ttatgtcggt gttccaggaa gtgttttaat ttaataacga
    53401 agaaattaat tgtttgtaga atgaaggaaa ctatttattg ggtagatgaa tcaccacgaa
    53461 tagtcaaaag gagatttcag gatatgccaa aaatgaaaaa aatcatttta gcagtaatgt
    53521 tattttctac ggttatatct tttacagccc cttttttgcg tacttaagct gattttaagt
    53581 tttgaccctt agtctggatc tacgaggtga gagtcaagaa tgaaaaaaat aattggagct
    53641 tttgtatttg caatcattat cattattatc tgttttcaaa tagatgtttt tggtcaaaaa
    53701 aagatagttg gacaaacggt cagcagtacg aacagtacgg ttacaaagac aaaggaatca
    53761 tttgatgata cagaacaaga gacattaatc aaaatcggaa aaaatgaccg tacactatat
    53821 acagatgact cgctaactac cccacttgca actataaacg gcggagagct ggcggagttt
    53881 ctttctgaaa caaaaaatgc ttatcagatc aagacaaatg atggctatac tggatattta
    53941 gccctcgaag atggaaccaa agtcacaaag aatatacaaa caaaaccgga agagctatct
    54001 gatgcagtga ttgtattaga tcctgggcat ggcggaaatg atactggggc attaagcaat
    54061 gatgaacaaa cagaagaaaa agatataaca ttaagtacag ccataaaagt aaaaaaggcg
    54121 ctagaggatg ctggagcaac ggtttatttg acccatacta cagatgaatt agtacagctt
    54181 ggagatatat gcgactacag tgaagaaaaa aaggcagatg tctttatcag tttacacgca
    54241 gactctacgg aatatgcgaa tgaagcaact ggaatcacga catattatta ctatggacaa
    54301 gaggaaacat tagcacagac aattgctgac tccttcactg atctgcctct ggattcaaga
    54361 ggaatctcca ctgggaacta tcaagttctt cgagaaaatc ttcaaccttc tattttaatc
    54421 gagatgggtt atatgaataa tgatagtgat ttaaaggaat tagtaacaga cagttatcag
    54481 cagcagattg ctgcaagttt gacacaagca ttgaccactt attttcagta ataaataagc
    54541 ccagccaaac aaaaatagct cctcatattt ttcgtttggc cgggcttatt atcgcagatg
    54601 caagcttttg aacaccgttt aaggaagagg ttgtgagcct gccgtttaac tccgcgtcac
    54661 aaggagcaat ttcaaaaaac agcttctcat gtttgatgac tattgtgact tgtgaccgag
    54721 gagttggcat gagaacaccg tttattcgga acaagggact gtgacatgac ttttgtcaca
    54781 gttccattat ttttttagca gcttcaaagc tttttctgta ttggcaaaat gaagtttggc
    54841 atatttttca agcataggca tgccgccttt ctccaatagt tttgccgcta cttggtcaga
    54901 tttcgttcca gctcctgatg gaagggtgat tccagcttca gctgatgctt tgtgtaactc
    54961 ttccaaaaag ctggcacgac tgatgataga agcagcagca acagctaaat gatattgttc
    55021 tcctttagta acgaagtaca gtttttcttg taattgattt ttttctaaac gcgcatattt
    55081 tttaaaattt gcttccggcg taaactgatc gatcaaaatc gcttctggtt tttctggctc
    55141 gatttttttt agcagcaaat ggatcgcttg attgtgcaaa gcgactttca tccgaacggc
    55201 attgtatttt ggttggatct cattgtattt ttctggagat aagacaagca gtttataggg
    55261 gatggttttt tttaagatgt cagcaagctg gatgatttgg ctatctttta actcttttga
    55321 atctctaaca ccaagtttac gtaattctgc aagctgatca cgtttcacat aagcagcaca
    55381 tactgttagc ggaccaaaat agctgccatt tccgacctca tcactaccta aaacggataa
    55441 ttgactgata ttttttggca aagaagaggc tgtttttgct ggcttggctt gtttatcctg
    55501 tgcctccccc catttatcag cttctattgc tgcattcgta ccttgaaaca tcacttttcc
    55561 ggatgtataa gcggtaatgg tcgtcccgtc tttttttgca gcaaagctag tataaggaat
    55621 ctgtttattt aacaaataag agcgatagta tgctttcatt tgactaagtt ggtcgtttgt
    55681 tgctttgata atgacgttgc tcataaaatt ctcctcgttt ttatacataa aactataccg
    55741 caactcacga cttttcgttt tctaagagat tgcgagacat agcatttttt taaagtttat
    55801 catataatag ttaagtatgt gaaaaatatt tgtggagaac ggtgaaagaa ccaacttcat
    55861 ggtacactaa ataaaacttt catcaaatag gaggaaatga ttcgtatggc gcacgaaaaa
    55921 acacgctaca aagcagtgat tgccaaccaa acatatacta ttatcggacg ggaaaccaag
    55981 catcatatgg atatcgtaac gaagctgatc aatgaacagt tagcagaatt gaaacaatta
    56041 tcaccacaaa tggataatga acaagcagca atcttgatgg ctgtcaatgc gctttcggat
    56101 caattgaaga aacaagaaag aatcttggag ctggaagaag aaacagcaga attaaagaaa
    56161 aaaatgatca aatttacaga gcttgaaaat cgtgtgaaac gcattgaagc aatcgagaac
    56221 gaagctcggg aagtattgaa agaaaatggt caagcagatc ataccattaa aaatcatgtg
    56281 gaagcacaac agattttaaa cgagaaacga aaaggacaaa ttaaacaaaa atcttctaat
    56341 taagatcctt ttatcaaaat aagaaaaatt taaaaaagtt agaagagaaa ggaacgtagc
    56401 atgctgagtt tgctgatttt atttttattg ctaattgcgt ttttttctgg agcacgtcgc
    56461 gggtttgctt tgcaaatcat attcgcgatt ggatatgtat tgtcatttat tgctgcccag
    56521 catttttaca aaccattagc aagtcatttg gaattataca ttccataccc agctgtcacc
    56581 ccaacatcaa agttagcatt ttttgatcag gtatttgctt ttcacctaga tgaagctttt
    56641 tatgcaggaa ctgcttttct gattattttg ctaattggct ggctgcttac ccgatttgtg
    56701 ggggtttttg tccatggatt gacgtatgtg ccgatcttga gacaggtaga ctggattgca
    56761 ggaggcatcc tgtcactaat catggcttac gttactatat ttttgatttt gcagttactt
    56821 gcctttgttc cattagatgt ggtccaaaat caattcggcg agcatagttt cgctcgtttt
    56881 atcgttgaga gaacgccatt tcttaccaac aagatgtatg agctttgggt aacgaatatt
    56941 ttgaattaag gaaaatagtg ctggaaaata tttcgttttt tgtacagagt agtttattta
    57001 agaaggctgc gtagcgtatg tccggcacag ctcttttttc atagtgaaag ataaggtgat
    57061 aaaatgaata accgaatcct tgaaacattg gaatttgaaa aagtcaaaca gatggtcaga
    57121 caatttgtag tgactgcaca aggaaaagaa gaactggcag aattggtacc agtgagtgag
    57181 aaacaaacga tcacaaactg gcttcaagaa actgaggatg gattgaaagt gcaacgtctg
    57241 cgaggcggga tccctatacc taaacttgaa aatatccgtc cccatatgaa acggatcgag
    57301 atcggagcag acttgaatgg agtggagctt gcacaagttt ccagagtatt gtctacgaca
    57361 agcgaattga atcgtttcat tgatgatctt tctgacagtg aaatcgaatt tgcacgtttg
    57421 tatatgtggg cagatcagtt agtcacgatc cctgttttga gccgccgttt aaaggaagca
    57481 atcgatgaag acggacgcgt gactgatgac gcttctcctg agttaaagag cataagacag
    57541 aacattcggc gaagtgaaca agctgttcgt gaacagttag atgggatcgt ccgtgggaaa
    57601 aatgcaaagt atttaagtga tgcgatcatc accatgcgaa atgaccgcta cgttatccca
    57661 gtcaaacaag aataccgcgg tgtatttggc ggtgtagtcc acgatcaaag tgcttcagga
    57721 cagactttat ttattgaacc aaaacaagtg gtggatttga ataatcgttt gcgtcaatac
    57781 caaatcgctg aacgaaatga gattcaacgt attttaagtg aactttctgc tgaacttgtt
    57841 ccccatcgtc aagaaatcat ccacaatgct tatgtgattg gtaaaatgga tctgatgaat
    57901 gcaaaagcac gatttggtaa agaagtaaaa gccatcgtgc cgggaatcag tgaagacaat
    57961 catgtcgtct tgaaacaagc aagacatcca ctgatcgatc aggaaaaagt agtttctaat
    58021 gacatcacaa tcggaaaaga ctatcaagcc atcgtcatta caggacctaa cacaggtggg
    58081 aaaacgatca cgttgaagac tttaggtctg ttacaactga tggggcaagc aggattaccg
    58141 attcctgcag gtgaagaaag tcaaatcggt atttttgagg aagtatttgc ggatatagga
    58201 gacgaacagt cgattgagca aagtctatcg accttttctt ctcatatgac gaacactgta
    58261 gatattttat caaaagtcaa tgaaaaaagt ctggtattat ttgacgagct cggtgcagga
    58321 acagatccgc aagaaggtgc tgctctagca atcgcaatct tagatgatct tggtaaaaag
    58381 tctgcttatg tgatggcaac aacgcattat cctgaattga aagtttatgg atacaatcgg
    58441 gcaaatacga ttaatgccag catggagttc gatgtggata cactaagtcc aacgtatcgt
    58501 ttgctgattg gcgttcctgg acgaagcaat gcgtttgaaa tctctagccg attaggtctt
    58561 gatacagaag ttattgatga agcgaagcag ttgatgaatg atgagagcca agatttaaac
    58621 gaaatgatca cagatttaga gaatcgccgg aaaatggcag agaccgaata tctggaaatg
    58681 cgtcattttg tttctgaggc acaagaactt cacgatgatt tgaaagaagc ttacagctat
    58741 ttctttgaag aacgtgaaaa agaaatggaa aaagcaaaga aaaaagcaaa cgaagtcgtg
    58801 tcagaggcgg aagaaaaagc agaaaaaatc attgctgata ttcgtaaaat gcaacagcag
    58861 attgggcaag gaaatgtgaa agagcatcag ttgatcgatg caaagaccca attagcaaat
    58921 ctacatcaag aagaaacttt gaagaaaaat aaagtattga agaaggcgaa agaacaaaaa
    58981 acgttgaaac cgggagacga agtgttggtt acgacttacg gccaaagagg gacgctttta
    59041 cgtaaaaacg ggaatcagtg gcaagtagaa atcggtatat taaaaatgaa tgtgtccgaa
    59101 gacgagctga cgcctgttgc tcctcaaaaa gagccgacac aacgagttat ccatgctgta
    59161 cgatctgaat ctagtagtca cgtgccgaat caattggacc ttcgaggaaa acgatacgaa
    59221 gaagcgctaa gtgaggtaga tcaatatttg gattctgcca ttctagctgg ttatcctcaa
    59281 gtgactattg tccacggaaa aggaacaggc gcacttcgca agggaattac tgattatctt
    59341 aaaaaccatc ggagcgtcaa aagctttgag tttgcaccgg caaaccaagg cggaaatggt
    59401 gcgacaattg ttaaatttaa gtaaagctta ctaaaggtaa gcagatggtt cgctatccaa
    59461 gtatagaaat gctatactaa tcatagattt taaaaatgga ggtctttgat atgtcacaag
    59521 taattacaga taagacattt aatgaagaaa cagataaagg acttgtattg attgattttt
    59581 gggcaacttg gtgtggtcca tgtcgtatgc aagcaccgat tttggatcag ttggaacaag
    59641 aatatgatga agaagaattc agaattgcta aaatggatgt ggatgaaaat ccagaaactc
    59701 ctcaacaatt cggtatcatg agcattccaa cattaatgtt gaaaaaagat ggtcaagtag
    59761 tagaaaaagc tgttggtgtt cattcaaaag aacaactacg tcaaatgatc gatcaatatt
    59821 tataaaaact tacagcaaaa ataagctgag ggtgggactg aatccagttc cgtcctcggt
    59881 ttttttgcgg ttgagttaag gttattcaaa ttaatatttt ttgagtataa ttacgttgtc
    59941 aggctggatt gtttttttga cagacatgct ataataactt taattgaata tgaaggggag
    60001 taccagatga acgaacgaat caaaaacaaa ttagctttac ttcctgatca gcccggctgt
    60061 tacttgatga aagataaaaa tggaacgatc atttatgtcg gcaaagccaa aatattaaaa
    60121 aatcgtgtcc gctcatattt tactggcagc cataatacga aaacggaacg gcttgttagt
    60181 gaaatcgaag actttgaata catcgttaca gaatcgaata tcgaagcatt gctcttagag
    60241 atcaatctga taaagaaaaa tgatcctaaa tacaacatta tgttaaagga tgataaaacc
    60301 tatcctttcc ttaagataac gaatgaaaaa tatccccgtt tggtgattac tcgtaaagta
    60361 ctaaaagaca aagcactgta ttttggacca tatcccgatg tcggtgcggc gaatgagaca
    60421 aagaagatcc tcgatcgatt atttcctctg agaaaatgca aacctagtca gacgaaggag
    60481 ccttgtcttt actatcattt gggacaatgt ctgtgtcctt attatttcga cgtagatccg
    60541 aaagtctata cgaaaatcgt tgatgaagtg aaaaagtttt taaacggagg acacgaaaaa
    60601 atcgagtcag agatccatca gaaaatggaa aaagctgctg aaaacatgga gtttgaaaaa
    60661 gctgcagaat accgagacca gatccgtgcc attgagacaa tcatgactcg ccaaaaaatg
    60721 acaaatactg atttactgga tcgagatgta tttggttatg cgattgacaa aggatggatg
    60781 tgtgtccaag tgtttttcgt aagacaagga aagctaattg aacgagatgt ttcaatgttt
    60841 cctttctata acgaagcaga agaagatttc ttgacttacc tcggtcagtt ttatcaggaa
    60901 aatgagcatt tcattcctaa agaagtcttg attcctgata cgatcgacaa gcccagtgta
    60961 gaagctttgt tagctacgaa agtgctgcaa ccaaaacgag gagaaaagaa aaaattagtt
    61021 gaattggcga ataagaatgc ctcagttgct ttgaatgaac ggtttgatct gattgccaga
    61081 aaacaggaac ggacgatcgg agcagttgaa cgtttaggaa acgcgatgaa tatcccgacc
    61141 ccaatacgta tcgagtcttt tgataactct aatatcatgg ggacgaatcc tgtggctgcg
    61201 atggtcgtat tcattgatgg aaaaccggca agaaaagaat atcggaaata taaaataaaa
    61261 acagtcaacg gaccggatga ttatgcatca atgagagaag tcatctatcg cagatattca
    61321 cgagtgattc gcgaagggtt gcctttacct gatttgatct tgatcgatgg aggaaaagga
    61381 caagtagatg tggcaaaaga tgtcttagaa aatcaattag gaatcgatat tcctattgct
    61441 ggcatggcaa aaaacgataa acataaaaca aatgagttgc tattcggtat agatttggct
    61501 gtagtaccgc ttgagcgaaa ttcaccagag tttttcttac tccagcgaat ccaagatgaa
    61561 gtccatcgat tcgcaatcac tttccatcgg cagctacgca gtaaaaacag ttttgcttcc
    61621 cgattagatg aaattgaagg gttaggacca aaacgaaaaa aaatgctgct taaagagttc
    61681 aaatcgttga aaaatatcac agcagccacg acagaagaat tacaagaaat cggactgccg
    61741 aaaaatgtcg cacaaaacgt atttgataaa ttacatcagg aatgaggaaa gggcacttta
    61801 caaagaaagt aaagtgtcct atcattttat gtacaacaaa aagagcgttt acgttttgtt
    61861 ggtaaataat aaatcgctta cgtctggtgt ctaaggatat atgtgatttc ttgaagaagg
    61921 agtgaagaaa tgttagaagt caaggatctt gttaaaactt ttgggaacta cacagctgtc
    61981 gatcatgtct ctttccaaat ccccgatgga aaaatcatgg ggctaattgg ccaaaacggg
    62041 gctgggaaga caacgacttt tcgtttgatc ttggattttt tgacacaaga ccaaggagaa
    62101 gtgttatgga atggccatca tcttggggag aaagattatg atgtcatcgg ttatcttccg
    62161 gaggaacggg gactttatcc gaaagtaacg attcaagacc aactgcttta ttttgcagaa
    62221 cttagaggga aatcaagaaa agagattgaa ccaaaaatcg atttttggat ggaaaaattt
    62281 caggtaaaag ggaaaaagac ggataaagta aaatctttgt ctaaaggaaa tcagcaaaaa
    62341 gtccagctga tcgccacgtt aatccatgaa cctaaattga tcattttgga tgagccattc
    62401 agcgggttag atccggtaaa tgctgaattg ctaaaagatg gaatattgga attgaaaaaa
    62461 catggttcat gtgtcatttt ttctagccac aatatggata atgtagaaaa aatctgcgat
    62521 catttgatca tgttgcgaaa cggaaaaatg gttttgaatg gaaaagtaca tgagattcgt
    62581 gaatcatttg gccgtacgaa gttattcttg gaatctggtt taagccaaca ggaagtagaa
    62641 gaaatcgaag gcgtgaaaaa agtgatcctt catgaagaca atacgttaga gattacctta
    62701 gaagatcctg aagctgggaa agaaatcttt actcgtgcga ctcagttcgg ctacattcct
    62761 atgtttaacc agcaaccgcc aactttggaa gagattttca aattgaaagc aggtgaaatc
    62821 gatgcgtaag ttttggatta ttaccaaaga tgtctattta aaaaatgtta agtcgatttc
    62881 tttcttgatc atgatattag tcccttttat catgctgggt atcatttatg tagcaggaaa
    62941 ctttgctcaa caaaatagtg atgtcaataa aatcggcgta ttggctgata atgagcaaat
    63001 cagtcagcaa atgagccaag tcaaaacaga tgattttgag ttcaaagcag ttgattctga
    63061 agaaaaagca caaaaagagc tttcggaaga aaaaatcgat gcgtatttag tagtctcaac
    63121 tgagaatgat aagataaatg ggatgcttta tagcgaaaat tcattaggac aaagtacaca
    63181 actactgata caacaacaac tgactggctt gcaatcgatg cttcgagcaa gtcaattagg
    63241 catttcacca gaagaagtag ctagcttgag ccaacaagca agtttgactc gacaaaaagt
    63301 caattttgat tcaaaaggaa aaatgacagt tggagaagat aactcgacag tccaatatgt
    63361 cgtaagttat gtagcaacga ttgtcttgtt cattattatt ttgacgtatg cgcagatcat
    63421 tgcacaagag atcgcttctg aaaaaggcac gcggatcatg gaagtgatcc tgtccagtac
    63481 gactgcacaa aagcattttt acggaaaact aacaggtgtt ttacttgttg cattaacgca
    63541 aatggcatta tacggtatta tttttggtat aggatacagt caattcaaag atatggaaat
    63601 ggtcaaaaat atattagacg gtatctcatt ggataacttg attggaccat tcttgtggta
    63661 ttctcttcta ttcatgatct ttggcatttt gattttttct gttttagcag ctttatgtgg
    63721 ctctttggtc aacaaagcag aagatacagc aaaagcaatt ttgccagtga cttatctatc
    63781 tctaggcgga tatatgcttg gattgatact aggagcttca gatccaaaca atatcgttat
    63841 tcggatcact tcgtatattc cattcttatc ttcatatatt atgccggttc gcttagcaaa
    63901 tgagacagtc ggtatgggtg gagcattgat ttccttgttg gtacttgtag ccgtaacatt
    63961 cttattgatg atcttgtctg caaacatgta caaatcgaat gtactcgtgt atagcgaagg
    64021 cggattatgg agttcattga aacaatcgat ttcaattatg agaaatgaac gaaaaaaagc
    64081 ataaaatata gaaaaatata gaaggaagct ggacatttat tgttcccagc ttcttttttg
    64141 tatagaccta tttctatttt tttattatat tggatatata tattcattga aaatagagca
    64201 taacaacttt ataatgttga gtataccaat ttttggaggc gttttaatgg accgctattt
    64261 agatttactt tcagagaagt tccctacaac ggaagatgtc atcacggaaa tcatcaatct
    64321 cgaagcaatt ttgcagcttc caaaaggaac agagttattt ttgagcgata tacatggcga
    64381 atttcctgct tttgatcata ttctgcgtat cggttcagga aatcttaaag aaaagatcaa
    64441 agaccttttc tctgaacaaa tgacggaaac ggagatcagc caattcacta tttttacggc
    64501 ttatccagaa tatgtgttga cgactgattg gtacaaaaaa caagataaat cccagctgat
    64561 ccatcgtttg atcgatcttt tacggtttac gacagtcaaa tacactcgat caaaagttcg
    64621 aaaaggattg ccgaaagaat atagctatat cattgaggaa ctcttgtata tcgatgatcg
    64681 tatcaacggg aaaaaagact atgtaaaaaa aatcattgaa caacttgtct tgatgaagga
    64741 agaagaaaaa tttttaacaa aacttgcgca gacgatccaa aaatctgtca tcgatcattt
    64801 gcatatcgtg ggtgatattt ttgatcgagg aactcaagca gccaaagtaa tggatcgaat
    64861 catggatttt tcctctgtag atatccagtg ggggaatcat gatattttgt ggattggtgc
    64921 gtattgcggc tctgaggcat gtttattgac gcttttacgg attgccgcac gctacaacta
    64981 tttatttgaa ttagagaaag aatatggatt aaatttacgt ccattatttt cttttgccca
    65041 tcaaacctat cagaagaatc cagtatttac ccctaaaaac aggaaagatc tatctgaaag
    65101 agagcaagaa gaattagaaa agatccatca agcactttct atcctccaat tcaaatcaga
    65161 acatcagttg ttgaatcgac gacctgaatt taaaatggac gatcgtaaat tgttggaaaa
    65221 aatcaactat gaggaatcaa cgatcgtttt agaaggtcag ctctatgagt tgaaagggac
    65281 ttgttttcaa acgatccagc cagatgatcc taaaaaattc ttggaagagg aacaaaaagt
    65341 gatcgatagt ttgatgtatt cattccagca ctcgttaaga atgcaaaaac acatgacgtt
    65401 tttgatcgaa aaagggggaa tgtatctcac gaacaatcag catgtactgt tccatggctg
    65461 tatacctgta gatgaaaagg ggcagctctt agcatttgaa ttagaccaat cttatcgcgg
    65521 aaaagaactg ctgggatttt ttgaaaaaca gataactgaa agcgcaaaag atttgactgc
    65581 aaatgaagat ttggcgaccg atttgatttg gtatgcgtgg agcgggccat tttcgccttt
    65641 attcggcaag agtaaaatgg caacttttga gcgctatttt ctcacagagc ctcatacgca
    65701 cgtcgaaaaa agcaatccct attatcactt gcgagatgaa gagtggttca gtgaaaaaat
    65761 tttggcagaa ttcgatgcaa aagaagaagg ttcagcaatc atcaatggac acacgccagt
    65821 aaaagtaaaa aaaggagagt caccgatcaa agcaaacgga aaagcatttg ttattgacgg
    65881 aggtctatcc aaagcttatc aaaaaacaac cgggattgct ggctactcat tactatgcaa
    65941 ttcttacggt ttccaaatcg tgacacatta tccgttcttg cctattgaac aacaatttgc
    66001 aaaaaaatct gatcaaacga atgtaaaaaa agtgatcgag cagcagctcc cacgcaaact
    66061 taatcggaat acgacaaaag gaatggaatt acagcaacag attactcaac tccaaaggct
    66121 gttggattat cgaaaggacg attgagaaaa atgctagcca acattgctca atagactaaa
    66181 aagcgactgc aacaaaaggc gtgtcgcagt ctccttcgga attagctcaa aaaacggtaa
    66241 aatattagaa gctatttttc tgtttatttc tctaatactc aggtcagggc gctgatttca
    66301 cgacctcttc cttaaacggt gttctcctgc caactcctcg gtcacaagtc acaatatcca
    66361 acaaacatga gaagctgttt tttgaaattg ctccttgtga ctcagagttg aacggcaggc
    66421 tcacgaccta atcagaaaaa cgattaaaat tcattcacaa agaaatcgaa taaacgctgt
    66481 tcagatgaat ctacacgatg agaaagttcc ggatgccatt ggacaccaag gattttgtgc
    66541 atattatctt tactttggac tgcttcaatg agtccatcgt tggaaaaggc gatggctttt
    66601 aacaaaggag aaagatcttt gactgcctga tgatgatagg aattcacaaa gtatgaatca
    66661 gggagaaggt cacttaataa actgtccgaa acgattttga cttcgtgagt tgcaaactgc
    66721 ggggcagtgg gctgttgttc gtgttttacg gaccattttg gatataatga aagatcttga
    66781 taaagtgttc cctccaacac gacattcaat agttgaagtc ctcggcagac tgcaaaaatc
    66841 ggttttcttt gtttcaatgc ttccaagatc aatgcctgtt cgaattggtc tcgttgaata
    66901 tttgtttccg tcagttttgg atgagggtct tccatgtaaa gttgcggact aacatcctga
    66961 ccgcctgcaa gaatgagttt gtcgattttc tcaattagtt gaggcgctga atctggagac
    67021 atgactggca gaataagagg taatccttga gcatctaaaa ctgcatccac aaatccctgc
    67081 ggtgtatagc ttacttgatt tccttggaaa gtatctgtcg ctcgaatcag ttgattcccg
    67141 gcaatgccga tgattggttt catttttatt ccccctaaag tagactaatt gtaacaagga
    67201 tttaaaaaaa tttaaactat gtaagacttg cccctatact tatctgttct tgctgtgtta
    67261 ctatctgtaa agagaatttt cgtgtgaaat tcatgacgat agttgaaaat attgcttaat
    67321 ttgttataat aaaaagtaag cagaaataaa aaggttgggc gtaagcttca aggatctagt
    67381 tcttcaaggg gtgagaagga cattttattg aaggggcctg cctatactaa gttatcttta
    67441 gaggtacata ctttcaatga aaaaagaaag catgtacctc ttttttaaat cgaaaggaag
    67501 tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc agaagaagaa aatgagaagc
    67561 gtgctcgaac cctacggcag cagttgaaga cctatgcaga agaaaaagag caagaattgg
    67621 agataatcca aacgaacagt cggcaacagc tgaaacagtt ggtagaagaa aaagaacaat
    67681 tcgaaaagca agaattagaa aaagaaaaaa tgaaattgaa agcagaagca gacaaggtgc
    67741 aagcaacttt gaaagaccaa tatcaaaagc atcagagtca agcaatcggt gcaatcattg
    67801 aaagggtgaa agaaacttat ggccgtcact aagatggaaa aagtgaccct catttcagat
    67861 aaaagaaatc aggagaggat tttacaagca gtacaaggaa tccaaaatgt tgaaatccgg
    67921 gatctgtatc aaaatagaac aaacaaccag tgggtagaaa aatattttcc agataccacg
    67981 attattgata aagaagcaaa attaagcgct ttaggcaatc ggctgaaaga catccaagaa
    68041 gctatccaat tcatacaaca ccacggcgat agccgtcaaa agaaactcca tttgaaacgt
    68101 caagaacttt ccttacaaga cttggaagca aattattccg aagaaaattt catgaataaa
    68161 ttagaagaag tccttgattt aaaagaaaag tgggaacagc taactgaaaa acgtgatcgt
    68221 ttagaagaag aggaagaatg gcttcttcat tggcaacagc tggatattgc tccaagtatg
    68281 tatgcaagta agacgaccat ttttgagatg gggactgtga gtgcagcaaa ttttgaaagt
    68341 ttcaaggaag aactaagtaa gcttgatgac gtttatatgg aagaaataga ttatacgcca
    68401 aaacaagttt atctttcgta tgttgcttta aaaaaatcag ttgctgctat agaagaaatt
    68461 gctgggaaat acgggttcaa taaagaaacg tatccttatg aacaaaatcc taaagaaaaa
    68521 ttgcaagaaa ccaaacagca attatccatt gttcacgagc agcaaaaaaa gataacgaca
    68581 gcgttaggtc agtgcagcgg ctatatccaa gaatttgaat gggtagaaga agtcacactt
    68641 gccgttgcag aacgggaaaa agtaaaagaa cggtttatcc atgccactta tctgatcgtt
    68701 ttgcaaggtt gggtagatgc agaagaaaaa cagaatttga tgcatgtgtt aaacgaaact
    68761 gtatcagaag aagatatata cgttagtttc gaaacaccaa actcagaaga gattcagcag
    68821 gaagtcccta ctaaattgaa aaaccatccg cttatcgaac cttttgaatt gctgactgaa
    68881 atgtacagtc tgccaaaata tgaagaagta gatccaacgc cttggatgac accattttat
    68941 cttgtcttct tcgggatgat ggtcgcagat gttggttacg gattgctgat gctcattggg
    69001 acaatactag ctcaaaaact atttgtttta ccccgcggga tgaaacgttt cgtaaaattc
    69061 tttgagattc tctcggtacc atcgatcatc tggggattga tctacagttc atttttcgga
    69121 caggcattac caaaagaact atttggtatc cgcttgcctt tcccaatcct atctacgacg
    69181 gatgacgtca atacgatttt gattttatcc gtgattttcg gtctgataca gatcttggtt
    69241 ggattattcg tggcagcaaa ggaaaatatc aggaggaaag attacttgag tgctgtcagt
    69301 gatggttttg cctggcaagg gatcctgatt gggatcgtta ttgcattgat tggtgtcatg
    69361 ttgataaaaa atacagcatt tgtttatctt ggcgcggggc tatcgatcat tgctgcttta
    69421 tgtatcttaa tcgtgccgat tatccaatcg ccgtctaaag tcaagggtgc tgccaaagga
    69481 gcgtataatc tttacggatt gactggttat atcggtgatt tagtcagtta tacacgtttg
    69541 atggcactag gtatttcagg cggaagtatt ggcgcggcat tcaatatgct agttgctttc
    69601 atgccgccag ccgctcgatt cagtgtaggg atccttttga tcatcgcttt acacgcactg
    69661 aatatgtttt tgacactgtt aagtgcctat gtccatggtg cacgattgca gtatgtcgaa
    69721 ttttttggaa aattttatac aggaggcgga cgtgcctttg acccgctgaa aacggcggaa
    69781 aaatacgtca acatcaatca taagaaaaaa aacaataaat aattggagga tttttataca
    69841 atgatggatt acttaattag tcaaaatggt ggaatggtat ttgcagtatt agcgatggca
    69901 acagcgacga ttttttcagg gattggttca gctaaaggtg ttggaatgac aggtgaggca
    69961 gcagcagcgt taacaacaag tcaacccgaa aaattcggac aggctttgat tctgcaattg
    70021 cttccaggta cgcaagggtt gtatggattc gttatcgcct ttttgatttt tatcaactta
    70081 ggaaatgata tgtcagttgt acaaggattg aactttctag gcgcttctct gccgattgct
    70141 tttacaggtt tgttttcagg tatcgcccaa gggaaagttg cagcagcagg tatccaaatt
    70201 ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt ttgctgcgat ggttgaaaca
    70261 tatgcgattt taggtttcgt tatttccttc ctattagtat tgaatgccta agcataaagg
    70321 aggaaaagca gatgaacgcc attgaaaaaa tcatctctca gatgaatgaa gcagcagagc
    70381 aagaaagagc ggcgttagag caagaagagc gaatgaagat cgatcaaaac tttgaacaaa
    70441 aacgtacgca aatcgaaaca gaacatcaaa aacaaaaaga aaaacaaatc gaattacttg
    70501 aaaaaaaata ccgtcagctt aggaatcgcc aacaagtaga agtacgacaa gaaaatttga
    70561 atgcgaagca ggaattttta cgacgattgt ttgcagatgc aatagctgaa atggagaatt
    70621 gggatgaatc tgaacaaatc cagtttatca aaaattcatt gtattcatta cctttgacag
    70681 gcaaagtaac attcattgct ggagaaaaat cagcagctta tctttctcag acattgctgg
    70741 atgaatggaa caatgaactt ccctttatga tggttttaag tgatgaaact gttgctgatc
    70801 aagcgggttt tctgataaac gatcaaggag ttcagtataa ttttcttttc agcagccttg
    70861 tacaagatat ccaaggaacg atgagttttg agattgccaa tcaattattc gaataaggag
    70921 ggatcagtgt atggaatacc acgaactaaa tcccttgatt cgcggaagag agcttgaact
    70981 tttgtccaat gagacatttg aacggatgat tcaaacaaat tctgtcgaag cacttggtga
    71041 aatattgaaa tccacgattt acagtccata tatttatgac ggatatgaat atgacttcga
    71101 acagaatctt ttaaaggagc agagccgtct atttcgctgg ttaaaggaat cagcaccgga
    71161 gcctgaaatc gtttggatct atacgatgcg ctatactttc cataatctga aggttttgac
    71221 aaaagccgag atgacaaatc aaaatctgga ccatttgtat atcgacgatg gattttattc
    71281 attagaaacc ttgaaggatg ccattcatac gcaagtttca aatgaactcc ctgaaagcat
    71341 tatggacagt atacgagaag tacgtgatta ttttgaagag tctaccattc ttcagggaat
    71401 tgacgtgatt tatgatcgac agtttttgac agagcagcga cggcttgccg ataagctagg
    71461 atatcaagaa ttgctgacag aagtcattgc ttttattgac ttgaccaata tcacaacgat
    71521 ggctcgagga atattgcaga aaagaacata tgggttcatg acgacggtac tttccagctc
    71581 gggaagtatc gaaaaagaag tatttttgaa ctttgtagat aaagatatgg aagattacac
    71641 gaattttcta ttagagacag attatgctga ttttctgcgc cctgtcatcc gtgagggaaa
    71701 tcttgatctc gtaaagcttg aacagttgaa agatgattat ctaagttcat tgtatcaaga
    71761 agcacaaacc caggctttcg gaccactgcc actactagcc tttttgaacg caaaagaggt
    71821 agaaagcaaa aaccttcgtt tactggttat cggcaaaaga agccatttcg aaccagaaac
    71881 aatcagaaag cgggtgagac aagtctatga cgcataagat cggtgtagtt ggcgacaaag
    71941 attctgtttt gccattcaaa ttgtttggct ttgatgttcg ttatggtaca accaagcaaa
    72001 ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta tggcgtgatt tatgtcacag
    72061 agcaatgtgc agcattgagc ccagaaacga tcgaacgtta caaggaacaa atgatacctg
    72121 ctatcgtatt gattcccaat catcaaggat cattagggat agggctggaa gaaattcaaa
    72181 aaaacgtaga aaaagcagta ggtcaaaata tcttatagta tgaaaaggag atagaaattt
    72241 tgcaaattgg aaaaatcata aaagtctccg gacctcttgt aatggctgag aacatgtctg
    72301 atgccagtat ccaagacatg tgtctagtgg gagatctagg agttatcgga gaaattatcg
    72361 agatgcgtgg cgatgtggcg tctattcaag tatatgaaga gacttctgga attggtccag
    72421 gcgaaccggt tcgctctact ggtgaagctt tatctgttga attaggacca gggatcattt
    72481 cacaaatgtt tgacggaatc caacggccat tagatacctt tatggaaatc acacaaagta
    72541 atttcttagg gcgcggagtt caattgcccg cattggacca tgagaaaaaa tggtggttcg
    72601 aaccaacagt agaagccgga gaaacggtga gtgctggaga tgttatcggg atcgtagaag
    72661 aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg gataaaagga acgatcaaaa
    72721 caatcgaaaa aggttcattc actattgatg aaacagtatg tgtcattgaa accgaaaatg
    72781 gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag acgtagtcgg ccaatcaaag
    72841 aaaaattaaa cccggatgca cccatgatca ctggacagcg agtgattgat acattcttcc
    72901 cagtgacaaa aggaggagca gcagctgtac ctggtccttt tggtgcaggg aaaacagtcg
    72961 ttcagcatca aattgcaaaa tgggccgatg tggacatggt tgtctatgtg ggatgtggcg
    73021 agcgtggaaa tgagatgacg gatgttttaa atgaattccc tgaattgatt gaccctaata
    73081 caggagaatc gttgatggaa cgtacggtat tgattgctaa tacatcaaac atgccagtag
    73141 cagctcgaga agcttctatc tatacgggaa tcacaattgc ggaatatttc cgtgacatgg
    73201 gttatgacgt tgctatcatg gcagactcca cttcacgatg ggcagaagca cttcgtgaga
    73261 tgagcggacg tttggaagaa atgcctggtg atgaaggtta tccagcttat cttggttcac
    73321 ggcttgcgga atactatgaa cgatctggaa gagtcattgc attaggatca gaaggtcgcg
    73381 aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg aggggatatt tcggaaccag
    73441 tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg tcttgattcc agtttagccc
    73501 aaaaaagaca ttttccttcg atcgattgga tacaaagcta ttctctttat tcaacagaag
    73561 tagggaagta tatggatcat atccttcaag ctgactgggc atccatggtc accgagggca
    73621 tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt gcgtttggta gggattgatt
    73681 ccctttcaga taatgaccgt ctgacattag aagtggcaaa atccattcgt gaagattatt
    73741 tgcagcaaaa tgcttttgat gatgtcgata cattcacttc aagagagaaa caattcaaaa
    73801 tgttgaagat gatcttgacc tttggtgaag aaggacgccg tgcgttgtcg ttaggtgctt
    73861 atttaagtga gatcatggac ggtaccgtat cgattcgtga aaggatcgga cgaagcaaat
    73921 atatcccgga aacagaatta gaaaaactag atcaaattat tggtgaaatc aagcaaacga
    73981 tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta aagaatatcg tacgatcggt
    74041 gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg gtgtcaaata tgaagaatta
    74101 atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac aagtattgga agtccaagaa
    74161 gataaagcaa tggtccaaat attcgaagga acaagtggta tcaatttacg tgactcttct
    74221 gtacgatttt taggccatcc tttagaacta ggtgtatcgg aagacatgat cggtcgagta
    74281 ttcgatggtt tgggacgacc gaaagataac ggaccagaga tcctgcctga aaagcatttg
    74341 gatattaacg gagaagtaat caatccagta gctcgggatt atccagatga gtttatccaa
    74401 acaggtatct ctgcaatcga tcatttgaat acattagttc gtgggcaaaa attaccagta
    74461 ttttctggct ctggtcttcc tcataaagaa ttagctgctc agatcgcgcg acaagcaacg
    74521 gtactcgatt catcagatga tttcgccgta gtctttgctg ctattggaat cacttttgaa
    74581 gaagctgaat ttttcatgga agattttcgt caaacgggcg caatcgaccg ttctgtcatg
    74641 tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg ctactcctcg tatggctttg
    74701 actgctgcag aatatcttgc ttatgaaaag ggaatgcatg ttttggttat catgacagac
    74761 atgaccaact atgcagaggc attgcgagag atttctgcag cacggcgaga agttccagga
    74821 agaagaggat atcctgggta tctttacacg aacttagcta ctttattaga acgagcagga
    74881 agaatccgcg gactaaaagg atcggttact caaattccga ttctaacaat gccagaagac
    74941 gataaaactc atccaatccc tgacttgact ggttatatta cagaaggaca gatcatcttg
    75001 actagagagc tttacaagag tgggattcag ccaccaattg atgtactccc gtctctttcg
    75061 cggttaaaag ataagggaac tggacccgga aagacaagag aagaccatgc agctacgatg
    75121 aatcagcttt ttgcagccta tgcacaagga aaacaggcaa aagaattagc cgtagtttta
    75181 ggtgaatctg ctttatctga tgtagacaag atctatgcga agtttgctga gcggtttgaa
    75241 aaagaatatg tcaatcaagg attctacacg aaccgttcga ttactgaaac acttgatcta
    75301 gggtgggaac tgctatcgat gttgccaaga accgaattaa aacgaatcaa agacgacatg
    75361 ctggacaaat atctgccaga agggaagtga gttctgatgg cacgattgaa tgtgaatccg
    75421 acccgcatgg aattgactcg attgaaaaaa cagttgacaa ctgccacaag agggcataaa
    75481 ttattaaaag ataagcaaga tgaactgatg cgtcaattca tcctgttgat tcgaaagaac
    75541 aaccagctgc gtcaagaaat ggaagagtct atgacagaag caatgtctga ttttgtattg
    75601 gcaaatgctt cgatcacgga acctttcatc gaagaattat ttgttttgcc ggcggaaaac
    75661 gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa aagtacctgt gatgaatttt
    75721 gaatatgatg aacagctgac agacacacct ttggaatacg ggtatttgaa ttccagtgcc
    75781 gaactggatc ggtcaatcga tcggtttact accctgcttc caaaactttt ggaactgaca
    75841 gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg aaaagacacg tcggcgagtc
    75901 aatgcattag aatatatgac gatccctcaa ttagaagaaa cgatctatta tattcgtatg
    75961 aagctggaag aaaacgagcg cgcagaagta acaaggttga tcaaagtaaa aaatatgggt
    76021 accactgact aagtggtatc tttttttaaa agaggaaaac gatgattaaa caaagcaaac
    76081 aaataaagaa acgtttgccg gctgttcagc ttctcgcatt aggatttttt ctcctgattt
    76141 tagttggcgg cggcctactt accctaccat tttttagtaa tagtgggcat gggacaaatt
    76201 ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt aacgggattg acaacattga
    76261 atacagcaga gcattggaac agtgctggtc aatttttgat catgcttttg attgagatcg
    76321 gcggtcttgg ttttatgatg gttccgattc tatgctttgc attgataaag aagaaagtca
    76381 gtctcagcac acgtattata ttaaaagaag cgctgaatct agaagaagta tcaggtgtga
    76441 tgaagctcat gctttacatc ctaaaattgg cctttgttat ccaattgatt ggtacggttg
    76501 ctttatcttt tgtatttgtg cctgaatttg gctggttgaa aggtatctgg tacagtttgt
    76561 tccatgcaat ctctagtttt tgtaatgcag ggtttgattt gttaggagac agtttagcca
    76621 atcaccagca aaatgtttat ttgatcatgg tggtatctgc tttgatcatt tctggtgggt
    76681 taggcttcat cgtatggcgt gatttactgg aatatcatca gaaaaagaag atgacgattc
    76741 attcaaaaat cgcattaacc gttacaggta cccttttatt aggcggattc gttgtgttct
    76801 ttttcacaga gcgcaatggg gcaacgctag tggaagggaa tatgtttcaa cgattggcaa
    76861 acaccttttt tatgagtgtg acacctagaa cggctggata ttattcagtt gattacctcc
    76921 atatgagcca tgcaggtctg attttaacga tgtttttgat gtacatcggc ggaacatctg
    76981 ggtcgacggc cggcggattg aaaacaacta cgttaggtgt gttgctgatc cagatgcgtt
    77041 cgatgttgaa aggacgtacg agagcggaag catttggccg taccatccga caaggcgcag
    77101 tgttgcgggc acttacttta ttttttgtta cgttgacgtt gtgtgtagtc gccatcatga
    77161 ttttatcggt gactgaaacg atacctaaaa cttctggcat cgaatatatt gcttttgagg
    77221 tcttctctgc gtttggtaca gtaggtctta cgatgggatt gacgccagac ttgactgcaa
    77281 tagggaaatt gatcattata gcgcttatgt acattggacg agttggtgta ttgactgtgg
    77341 tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa atacaaatat ccagaagaaa
    77401 gtgtcatgat tggataattt catcttctga cagaaaccta gtgatttagt aaaataagaa
    77461 aataaaataa tttttcttgc ttcttggata ctttaagtgc aaaatgttcg tttatttttt
    77521 gaggcactac ccgttgttga acctcgggta gtgcctcttt tttattgaaa ggaatcaata
    77581 agatttgatt cctttattta tcaataggtt ataattcata tttttttatt ttttctttta
    77641 cgatacttag tccagaagct aaaagttcaa ggttattaga ggatagggaa attcgaacga
    77701 atgcatctgg ttgcgcacgt gtagtaaagc gtctggaatg ataaagtcgg ataccgttag
    77761 caagaaagtc attctcaatt atcttagggt caatctcagg atcaactgga agaattcgat
    77821 agtaagggac acgattcgtt ggtttttcta ctttgaaaag agaatcaaaa agctgattgg
    77881 ctctttttgt aagacttaat ttagtttcta agatcctatt tgcttcattt gaatggagga
    77941 tttgagtgat gacttccaca tctaatccag aagttttcac atttatatta aaaattgctt
    78001 gttctatctt gctttggaca tgtactggaa ctacaagata agcaactcgc aatccagaac
    78061 aaataaattt tgtcattcca gctaagtaga ttgtttggtt aggtaataaa ttttggaaag
    78121 gaggaatgat cgtatgttga tagtaagttg ttaaaaatga atggatatca tcttcaataa
    78181 cccatagacc ttctttttca atcacttcgg ctaattgctc tcgtcttttg tgagagattt
    78241 gaaaccctat aggattatta caagaaggca taagaaagac accatgaatc ttcttttttc
    78301 tacattcctg aatcaatata tcaggtcgca ttccttgctc gtcaaaatca attggaacga
    78361 tctctaaatg atataactga gccaattcaa tgaaattagc gtatgtatat cggtctgttg
    78421 ctattctatc acctggagag aaaagtgcag aaagtgtgat agccaatcca ttttgaacac
    78481 cggaaacaat agatagagat tctaaggacg gaatgactcc ttgagttttt aaccaatttg
    78541 ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg gtaattaagc aaaccaacaa
    78601 gatttgggtt attactagtt gattgaataa acgggacaac gaatttatta cattcttcaa
    78661 aagaactaac cagaccaaaa tcaatgatat gttcggttac ttcattggta gagatggtga
    78721 tggactcaaa gacattggga gaaataaatg tgccacttcc aatattcgta tacagcaaac
    78781 ctttctcaat tccatattta taagccttgc caacggtagt aaaatttaaa tctaaataat
    78841 cagctagctc tctttgggag ggtaactgag tgtttttctg taatttattc tttaaaatat
    78901 cttgttctaa ttgttgaatc aacgatcgat aataaggacg cttcaatttt tgtttgtctg
    78961 gtcgccaagt taacgggtaa ttgtcataag aattaatagg cattttctcc actccttaaa
    79021 attgtatacc atacaatttt accattgatt gtattgattt tagaagttaa tcttttgtga
    79081 ggagggaatt gtctatgaaa attattaatt ttgaggaagt agtagcttct tttagttttg
    79141 aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta tgaaagtggt aaaatcagcc
    79201 aaaatcctcg attggtggaa attttacctg acggaaaagg caaaaatatg tttgcgatga
    79261 tgcctgctta tttgggggag aacagatatt ttggcacaaa agtcattacc gcttttccgg
    79321 ataatcatca gtatcattta ccttctcatt taggagagat tttcttgttt gatgctcaaa
    79381 acggactacc caaagcattg ataaacgcaa atgcagtcac ctggattcga acagctgctg
    79441 tatctgcgct ggcaacagat tacttagcaa atccgcatgc agaaacactt gctttaattg
    79501 gagctggtca acaagcattg tcgcatttga ctgcgatttc taccattcgt cccatcacta
    79561 cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac ttttatcgct aaagctaaaa
    79621 aacagtatcc taaaataacg tttataaatg caatatcagt agaagatgca gtacgtccag
    79681 cggaaatcat ttgtacgttg acctctagta aagaggcatt tcttcaaaaa gagtgggtaa
    79741 gggaagacgc acatatcaat gctgtgggca catttactcc tgatacaaga gagataagta
    79801 catcgttgat ggaaacttct caaatctatg tagatgatta ctcagctgcc ttaacagaaa
    79861 gcggggacct gcttatagcc atggcagaag gagatttaga ggaatcttgt attgttggta
    79921 cattaggcga attagtttct gagaaaaaaa cattttataa aggagaatcg aggccgacga
    79981 ttttcgacgc agttggtcta gctattgaag atctttgttg tgcagaatat atttataaca
    80041 aattagagaa aggggcttta aaatgaactt agattattac gtagttgatg catttgcaga
    80101 tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta gaagaatggc tgccagaagg
    80161 tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa acagcattta cagtgaagaa
    80221 aaaccaagaa tttgagctta gatggtttac gccagatcga gaaatcgatc tttgtggtca
    80281 cgcgacatta gcaacagcat ttgttttatt taactattac aaaatacctg atgaaacgat
    80341 taaattttct actcaaagcg gtaatctatt tgtgacaaga attaaagatt attattacat
    80401 ggattttcct agtattatgc cgaaaaaagt gccgatattg tctgaatatg aagaagcgat
    80461 tggggctaag attaaagaag cctacttagc acgtgattta tttttcgtat tagaagatga
    80521 aaaaacggtg gctaaattgc agccagattt tacagctatc aaaaattttg aattaggaat
    80581 aggagtcatc gtgacagcag aaagtgtgca aaaagacttt gtttctagaa ccttctttcc
    80641 aaaattaaca atcaatgaag atccagtatg tggatcagca cattctaatc ttattcctta
    80701 ttgggcagaa agaatgaata aaacaaaatt gtcagcttat caaatgtcat caaggggcgg
    80761 ggatctagaa tgtgaattaa aagaagatcg tgtgataata ggaggaaaag cagttttgtt
    80821 ttctaaaggt acctcgttta tttgatttct ttcaaatgaa ttaaaaataa attggtggag
    80881 agtggcaacc ttatagctac aatggttgtt aaaaaaagac gcaaactttt tcaatttaat
    80941 gaaaagtttg cgtctcattt taattattgg tgtttgtttt ttattcaatc aagagtaaaa
    81001 tgccccatac taactatcct cggatgactt cgattttata accatcaggg tcaatgacaa
    81061 agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc agtaatctca agaccggcag
    81121 ctttatgttg ctcgtgtaat ttttctagat catcagctgc tatagcgata tgaccatagc
    81181 cgtctcctag atcatacgca ccatgatcat agttgtaagt caactctaat tcatagtcat
    81241 ccccaggaag tgtcaaataa acaagtgtaa atttgttttc tggaaaatca cggcggcggc
    81301 tttcttcaaa accaaatgcc ttttgataaa attcgattga tgcttcaaga tctttcactc
    81361 gaacacatgt gtgagccatt ttcatagatt catctctcct tttcctttta ctcaatcata
    81421 acaaaaagaa gtaaggaaat agttgatttg tgcttgttca tgagaaattt ctcatgtaaa
    81481 atggatagaa aataaaactg ttaaggtgga aactattcat ggataaacca atttttggtg
    81541 aaaaaaagca atttgctgat tatcaaaccc gttatgcagc atatattgtc atagaaagag
    81601 atcagcagat tgcagtaatc gaggctccaa atggtgcttt ttttcttcct ggcggggaaa
    81661 ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga gctgatagaa gaaatgggaa
    81721 ttgtggcaga aatttcttct tatctgggag aagctgatga gtatttttac tcgaattatc
    81781 gtgcaactta ttattataat ccaggatatt tctttgttgc tgattcttgg aagcgtatag
    81841 gagaaccaac tgaaaagacc aataaaattt ggtgggtgag ccctcaagaa gcgcttgtga
    81901 aattgaaacg tggtagccac cgatgggcag tcgagagatg gatcgaaaaa aataaaaact
    81961 gaaagaaagc gagtagatca gctttctctc agttttttta tttattacag tacatatttt
    82021 ttgattgctt cagctacacc gtgctcgtcg tttgatgaag tgatgacatt tgctgcttct
    82081 ttgacaagag aaacggcatt tcccattgct actcctagac cagcatattc aatcatggat
    82141 aagtcgttct cgttatctcc gatagccatg atttcatctt gatcaatacc aaggtgctgt
    82201 gcgagattcg caactgccgc acctttactt gcttctttat ttagtacttc gaagtaatag
    82261 ggcgcacttt tgaccgttgt gtatttatca cggaaagttt gcggtaaacg cgcaattgct
    82321 gcatctaaaa tttctggttc gtcgatcatc atcattttga cgatgttcat gtctggtgtc
    82381 atttcttcag gtgttcgata ttttagcggc atcttgacta aacttgcttc gtggatcgta
    82441 taagcgctga tatctcgatt aggcgtgtag atcgctttgt catcgatcga atggagatga
    82501 ctgccgacac ggcgtgccat cacttcgatc tctaggaaat cttcatgtgt cagtccgtga
    82561 cgggcgatga ttttacctga tttcgtttgt tgtacgagtg ccccgttata agtaataacg
    82621 taatcattat cttgaaaaag gttcaactcg tttaactgtt cctggacacc tggtaaggga
    82681 cggccagtgc ataaaacgat cgaaacacct tttgcaacag cagcggcaat cgcttctttt
    82741 acttcttttg ttacttctct tttctcattt aataaagtac catcgatgtc gatagcgact
    82801 agtttgatag acataatttc ctccaatata ttttaattta tttcaatcaa tgcgccatta
    82861 cggatatggc tggcaaattc ttgataagtt tcgtcaaata aatcataatg atcacgcaag
    82921 gacggatcaa ccatttcttt tggaaagaaa aatcgctcat ctccttgttc ttgtcccgct
    82981 aatgcagcaa caagctgact aacctgtgat aattctatca aagttccgtc atttcgcaaa
    83041 atctcgattt gtgtgcgatg tctgccttgt tctgggcgat aaaaatcata aggtagatcg
    83101 tagctagaat tcacagcagt gtaataaaca ggattatatc cgaccttttc tactaacaaa
    83161 gtgagttctt ggactaattt tgaatcccgg ttgccagaaa aagtagcaga tttcagtggt
    83221 ttacgattca aaaaacgttt agctaaatca tttaaaatag gatcagcaga ttcagaccat
    83281 tgagtaaagt aagtgcccaa gaccccatca tcaagtttga ggtattcttc taaagtaaag
    83341 cttccgtcaa gaaatggcag aagtaattga gaatggagtt caaaactgct ggcatcttct
    83401 tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa ttacttccat accacgggaa
    83461 acaggatgga agtacacttg cacatacatt tgatatcggc taacgatata atcttccact
    83521 gcatgcatgc cactcatgga aaaagcgatc ccgccttcat aaggacgaat cacacgtaat
    83581 attcgggtaa gatcaaatgt tccatattct gttccagtga aataagcatc ccgaagcaaa
    83641 tagtccattc gatctgcatc gatctgacta gaaatcattt ggacaacttg tgggttgggg
    83701 taagtttttt ggatcacact agctaccttt tcaggaaaac cttcttctac tcggttaaga
    83761 atctgataca cttctgtttc tggagaagtg atgatctcta cagtgatggc ttcatgattc
    83821 gtatggaaga tatgttcaaa tgtatgagag taaggaccat gaccgacatc atgcaacagt
    83881 gccgcacata aagtcaccag ccgttcctga tcatcccagc ctccgttgcc tattttttct
    83941 tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg aaatctcata aacgcctaat
    84001 gaatgagtaa aacggctatg ttctgctccg tgaaaagtga aagaagaagt gcctaattgt
    84061 ttaatgcgtc gtagacgttg gacttctttc gaattgatca aatctaagat tacttgatgc
    84121 tggacatgga tatagttatg gactggatca cgaaaaactt tttccatagg cagcatttga
    84181 tatttataag gggttgtcat aatgtagctc ctttatgtta ttacgttgtt ccattctctg
    84241 gatttggttg ttccattgct ccagctggat ttcttttttt agccagtcgg tagaatcctg
    84301 taaatcactt gcagaataca gcttttcaaa agcttttgca aatgcttctt tgacttcttt
    84361 tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc attgtagcag gatccactgc
    84421 aggatagcca tttgtaccaa agtcttcttt taaagcagat tgataaaatc gcttcatgac
    84481 ttgcccgcgt ttttcctgat taccgttgac acttaagtac atcataacag aaatcccatt
    84541 tttgatccga cgctgagcga taccggcaaa ttttttgcca tggatgctta aatcataagt
    84601 tccaggacaa taagaatggg tgatttcgaa tgcttgtatc ggtgcctttg gaaaagcgta
    84661 tttagtcaat aggagcattt gctcgtaagc gtcatctatg gttatttttt ttgtgtcact
    84721 ttgggggaaa atcaaagaaa tattcaaaat tccttcatct gatacgatcc ctaatccacc
    84781 tgaatttctg atcactggag cgtaacctgc atctttcagt gtttggatcc cgtcacttag
    84841 aaaaggagtt cgaacatcct tcatacctaa gatgactgtg cagtcatatt gccagaaatg
    84901 taaaaagatt tgctggtgtt ctttagaata ttccgttaat atatctgtta atgcaaaagg
    84961 ggaaaagtcg tttttttgat aaatgtgctg atctagtcga atcgcagggt tcattcaacc
    85021 ggctcctttg tataaattca tattttctac aatattatac tctaaaatca aagagttgtt
    85081 ttggaaaaaa ggttttctgt aaaaatggac aagttggttg acaaaacaaa agaaactagg
    85141 aacaatgtag ctatgagaag taaaggagaa tgaataatgg aattatcaca aggaacaccg
    85201 atttcaatca aattgcgtac aaaagtaaaa cagcaagggg aagtgcaaga tttttatttt
    85261 gatttgaaag ggcaaatggt gacaattggc gatacgctgt acatacgtta taaagagatt
    85321 caggaggaga cgggcgatga gattcctgta acgatcaaat tagttccaga tggtcatgta
    85381 cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat ttggctataa agaacggtta
    85441 gaaacatcct atcgaacacc atacggtatg atccagattg ctacttttac gaaagaactg
    85501 catgttagtt tgaaagaccg tcccacagga gggaaggttc gaatcgatta tgatctgttc
    85561 atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg attttacagc gtaaatataa
    85621 aagaaaagtt tgattttttg tgtctgattt tgtatgataa ggagtagact gtgaaaggac
    85681 gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca aaagcgaatt atcaatgatc
    85741 gaagtagcac acgcgatctt agaacaacgt ggcgatgtca tggatttttc tgatttagct
    85801 aaccagatcc aaaactatct tgggaaatca gacagtgaaa ttcgtgattc actcgcacaa
    85861 ttttatactg acttgaatat tgacggcagc tttatctcat taggggataa tcgttggggc
    85921 ttgcgttcat ggtatgctat cgattcgatc gatgaagaag taaaccatgg aatggacgaa
    85981 gaggatgaag atactccacg tcgccgtaaa cgcaagaaag tcaacgcctt tatcaatgat
    86041 gatgaagacg cgatcgatta caatgacgat gacccagaag atacagatct gacagaagaa
    86101 gatgacgatg atctgtttga tgacgatgat gatgaagatg aagaaatcgc tgcttataat
    86161 tctgacttgc aagaaatcgg agcagatgac ccgacagatg atgaagaaga cttgccagga
    86221 aatatcgaag aagatttaag tatcatagac gaagacgatg atgatgaaga ttatgaagag
    86281 gaagaatttt ctgactctga aaaagaataa acattatttt cttacgagag gttgtgacag
    86341 agacgatcag cctatcagaa taaggaggtg tgacacgatt tttgtcacac cttctttttt
    86401 gtatataaaa atcccaagta aatacataaa aaataaaaaa attgaaactt ttagcgcacc
    86461 ttgtacgtca tattaagtga ggcagaaagg agtggagaat gatttttact ggatataaga
    86521 aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg actcatcgaa actgattatc
    86581 aaaaaatgtt ccgtatcacg atgaattacg tacatgataa agaagaggcc ttagatgtga
    86641 tgcaagatag ttttcataaa gccctgaact attttgaaaa agaaaaagag atcgagcatt
    86701 ttagtgcatg gttttatcgg atattgatcc gcacggcatt agatagttgg cgcagacaaa
    86761 aaaggacgcc tgtggactta tttgaaattc aagatatccc ccaacagtta cctttagaaa
    86821 cttccgttgc agagctccat atgattttag ataaaataga cagtccggaa aaagagattc
    86881 tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat tgcgactatc ttggatatga
    86941 atgaaaacac agttaaaacg aaaatgtacc gctcattgaa tgctttacgt caaatcctag
    87001 aatgaaggag agaagagtgc catgtattcc caaaaagaaa atttaaaaaa actaaagaaa
    87061 acttataaag aacaagcaat tcccaaaggg cttaaagagg agatccgcca gcgttttatt
    87121 atcgaagagc aatcatttat aaaagcaaag cggagaaaga gacgtctcca agggttcgga
    87181 gtatctttgg ctatcgtaat gattacaaca agtagccttc tttttaatag tcaagttcga
    87241 agctttgcag aagatttacc catcttagga tcagtcattg aattgatctt aggcgaacgc
    87301 tttactgatc gatctgaaaa aatcgatatt caggtaccga agatcaatac acaaaatgag
    87361 aaagaaaata aaacaattca tggattaaat caaaaatact ttcgcgaagg acaagcagat
    87421 tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg atcattacca agttttggga
    87481 gattatcaga aaatcgtaga cgataaccgg tttctcgtga ttgaaaggca gatcacccaa
    87541 acagcagcag atagccatgt tgaaaaaaga tacgacacaa tcgacaagaa aaacagtgtc
    87601 cagctctcac ttccactttt attcaaagat gacacctatc tatctgtttt gacaaaagaa
    87661 gtcaaacggc agatggccga acaagtcaag gaagatccat ctaagtacta ttggactgag
    87721 caagatattc aagaagggac gatagaaaaa ccaacacttg ttacgcctac acgaagtttt
    87781 tatttgaaca aagagcatca attagttttg actttttctc aatacgaaat tgctcctggt
    87841 tatatgggta caccagaatt tgtcattcct aagtccgtga caaaaacgat tttggcatcg
    87901 gaagattatt tggatcatta gacgagaagt agttgcgact agcagtttca attttcaagt
    87961 aagtacaagt aaataataag aagagaaaaa gagaaagaag agatatagtg aaaagaaatt
    88021 atttagttat cagtattatt gctttatccg tgcttttgtt tttcgaaatt acttcggtgg
    88081 cctccttgat caccgaagta aaaggacaaa cacactcttc ggagcattcg tcacaatctt
    88141 tcaaacaatc agaacaatca accattaaaa gccaatcaac tgaaacagct aacgtcaaag
    88201 aagccattca agaatcagcg gaaaaggtac aaagtcagtc atcacaatca acacaagaca
    88261 gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc aatcagcttt gatgatggac
    88321 caggagcgac cacaacaccg cagcttctgc gaatcttaaa agaaaaaaac gtgcatgcca
    88381 cttttttcgt cttaggagaa aatacggcgc agcatcctga aatcgtgaag cagacagctg
    88441 aagcagggca cgagattggc aatcacacat acgatcatca gaatctggcc actctttctg
    88501 cccagtcgat gacggaggaa gtgacgaaag cagacactga gatcaaaaaa gtcactggca
    88561 aaacccccac ttttgttcgt ccgccctatg gttctgtcac gaatgtagga gcaacgatca
    88621 tccagcgacc gatcatcgaa tggtctgttg attcagaaga ttggaagaca agaaatcctg
    88681 atttgatttt gcagaagatc caagcaacag tatacgatgg ggcaattatt ttattccatg
    88741 atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat cgattatctg aaagagcaag
    88801 ggtatcgcat cacgacagtt ggggatttat tagggcatcc aacggctgtc gagaactatt
    88861 atggcagaaa cgatcatcgg ccagttcagt aagtgagaca agtatcttta ataaataaca
    88921 cattttaata agtagttgaa cacataacta ccttacttgc aaaggcttaa caatatctat
    88981 acaggtacaa caaaaaactg tccaccaatt ttctttggcg gacagttttc acttaaaaat
    89041 aaagaagcaa ctattcgtaa attatgctaa aatagcagta gaacgcgtcc tgagggaatc
    89101 gaacccccgt ctcaagaacc ggaatcttac gtgatatcca ctacactaag gacgcaagca
    89161 ctgggataat tgtaactaaa cagataaaaa attacaaggg gattggacaa aaaaatgaaa
    89221 tttgagcaaa atttttcaca aaaacagcag cagacacaga aactagccat gacgcaacag
    89281 ttgcaacagt ccatccaagt tttacaatat aacagtgagg agctgttggc attcgttgag
    89341 aatcaagcaa tggaaaatcc attggtggaa gttgttgagc cggaatggca gccagattac
    89401 ataaaagctt cttcatcttc ttatgaagga gaagagacaa attacctaaa tcagattcct
    89461 gatacaaaag ggtctttatt tgattcattg atcgaacaag tccatttgaa ttaccgagat
    89521 acttttttga ggaaaatcgt tctttatctt gtagaataca tcgatttgaa cggatttttg
    89581 acgattagtt tagaagaagc cggaaaagag attggagcta cgcctatcca aatgctcgat
    89641 gcgttgactc tgattcagca attagaacca gctggagtag gtgcacgtag tttgcaagaa
    89701 tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg aattagctta tatcgtgttg
    89761 gaagaatgtt ttgaggaact ggtggagcga aaatggaaag aaatcgcaca acgtttttct
    89821 gttgatctac atgctgttca gcagatattc gactatttac aaacgttgag tccaagccct
    89881 ggccggattt tcgaccgtag cagcgaattg tacattattc ctgatgtccg ggtattagtg
    89941 gacgacgata aaaatgtaca agttatctca aaccgaaaaa atcagccaaa tatacgcttt
    90001 caagagagtt acttcaaaca aatgtcacaa caagcagata aagaaactga aaattattta
    90061 aaagaacgga aacaggaatt cgaatggttg aagaaaacga tcctacaacg tggggataca
    90121 attttgcggg ttgctcaagt cattgtttcc cggcaaaaag ctttctttat cgacaaggaa
    90181 cgtccaatca agcctcttac gttaaaggaa gttgcaactg agatagatgt gcatgaatcc
    90241 acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag acttcggtgt atttgaatta
    90301 aaaaaatttt tcactacacg aattcctacg aatagtacag aacagacaga agacctttca
    90361 gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc aagaagacaa aaacaagccg
    90421 ttgtctgacc agaaattggt tgaattgctg aaaaaagatg agatagcgat ctcaagacga
    90481 acagtagcaa aatatcgtga tttattagga atcccgagtt catcaaaaag aaaacgttat
    90541 gataactaat cagtcaaaag actagaaaaa gtatttcact ttttctagtc tttttagttg
    90601 aaaaacgaga gcaaaactgt tagacttaca gtcgtgaggt tgagatttcc ctttattgat
    90661 gtgaaattcg aatagttaat ttcttttttt atcgtatatg ggtcgtttta agtctacatt
    90721 ggacgtaaag tgtccaacta aggagatcgc tatgctggat gaaataaaaa tgattgaatc
    90781 tgttgcacca gatattatcg aagtgttgca agaacgctat aaaattttac gaaatatcta
    90841 ttggatgcag ccgattgggc gtcgaagttt atcggaaagt atggggatca cagaacgagt
    90901 cttacgaaca gaaacagacc ttttgaaaaa tctgaatttg atcgacacct caaaaagcgg
    90961 tatgacgctg acaactaagg gcgaagaagt ttatcaaagc cttgaaaact tcatggatca
    91021 gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa tattttggta accaacgctg
    91081 tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg gctgatgcat tcggcgaagc
    91141 gctgagcgaa gccttagacc gactacttcc agaaggcgag aatatcatcg ctgtgatggg
    91201 aggaactact atggctgtgg tagccgaaca attgtctaat ctggaaaata agaaacggca
    91261 taacctgttt gtccctgcaa gaggcgggat tggtgaagcg ataactgtac aggcaaattc
    91321 tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac cgcgcacttt atgttccgga
    91381 acaattaagt ctggcaactt acaattcttt actcaatgag ccatctatcc aagaagtctt
    91441 aaacttgatt agtgaagcga attgtgttat tcatagtatt gggcgtgcat tacacatggc
    91501 agcacgtcgt aagatgactg aaaaagaatt agtcatgctg aaacaagcaa atgctgttgc
    91561 ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc gtttataagg tccctagaat
    91621 cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc atggcaatcg cgggcggaaa
    91681 atcaaaagct aaagcaattc gagcttatat gaaaaatgca ccaaaacaaa cgtggctcat
    91741 cactgatgaa gctgctgcaa atgagatttt aaaaggggta accctttaaa ataaatattt
    91801 ttttgatttt cataaggagg aaatcttaaa tgacagttaa agtaggtatt aatggttttg
    91861 gacgtattgg acgtctagca ttccgtcgta tccaagatgt agatggaatc gaagtagtag
    91921 caatcaacga cttgacagat gctaaaatgt tggcacactt gttaaaatac gacacaactc
    91981 aaggacgttt caacggaaca gttgaagttc atgaaggttc attcaacgta aacggaaaag
    92041 aagttaaagt attagctaac cgcaacccag aagaattacc atggggcgaa ctaggcgtag
    92101 atatcgttct agaatgtact ggtttcttca cttctaaatc agcagctgaa aaacatttaa
    92161 cagctggtgc taaacgcgtt gttatctctg ctcctggcgg aaacgatgtt ccaacaatcg
    92221 tttataacac aaaccacgaa acattaactg gtaaagaaac agttatctca ggtgcttcat
    92281 gtactactaa ctgtttagct cctatggcta aaacattgaa cgacaaattt ggtgttgttg
    92341 aaggattaat gacaactatc cacgcttaca caggtgacca aatgactcta gacggacctc
    92401 atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc aaacatcgtt cctaactcaa
    92461 caggtgctgc taaagctatc ggtttagtaa ttcccgaatt gaacggtaaa ttagacggag
    92521 ctgctcaacg tgttcctgta ccaacaggtt cattaacaga attagtaaca gttcttgaaa
    92581 aagaagtaac tgttgacgaa atcaatgcag caatgaaaga agcttcaaac gaatcttacg
    92641 gatacaacac agacgaaatc gtttcttcag atatcgttgg tatgacttac ggttcattat
    92701 ttgatgctac acaaactaaa gtaatgacag ttggcgacaa acaattagtt aaaactgttg
    92761 cttggtacga caacgaaatg tcatacactg cacaattagt acgtacttta gaatacttcg
    92821 ctaacttata agatagacaa acgtacaagt gtaaattata gacatgtaca tttaaaagcg
    92881 gggaagcaat cgcgcttctt ccgctttttt tgataataag tttattcagg aggaaataaa
    92941 atggctaaga aaacagtgaa agatatcgat ttaaaagaca aaaaagttct tgtccgtgtt
    93001 gacttcaacg ttcctttgaa agacggcgtg atcactgacg acactcgtat caaagcagca
    93061 ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag caatcctttt ctctcacctt
    93121 ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt tagctccagt tgcaaaacgt
    93181 ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg aaactcgcgg agaacaatta
    93241 gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg tattcgaaaa tacacgattt
    93301 gaagatattg acggtaaaaa agaaagcaaa aatgatacag aactaggtaa atactgggct
    93361 tcattaggcg atgtatttgt taacgatgct ttcggtacag ctcaccgtgc acatgcttct
    93421 aacgtaggta tcgcttcaac tggtatccca acagttgctg gattcttgat ggaaaaagaa
    93481 atcaagttca tcggtgaagc agtagaagaa ccaaaacgac caatgattgc aatccttggt
    93541 ggcgcaaaag tttctgataa aatcggcgta atcgaaaact tgattcctaa agcagataaa
    93601 atcttgatcg gtggcggaat gacttacaca ttctacgaag caaaaggaat caagatcggt
    93661 aactctctag tagaagctga taaagtggaa ctagcaaaag aattaatcga aaaagcaggc
    93721 gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag aattttcaaa tgatgttgaa
    93781 acacaagtaa tcgaaggaga cattcctgat ggtttgatgg ctttagacat cggcccagca
    93841 tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa cagttgtttg gaacggacct
    93901 atgggtgtat ttgaaatgag taactttgct aaaggtacaa tcggtgtttg tgaagcaatc
    93961 gctaacttag aaggcgcaac aacaatcatc ggtggcggag actcagccgc agcagcagaa
    94021 caattaggat ttgctgacaa attcacacac atctcaacag gtggcggcgc aagcttggaa
    94081 ttgcttgaag gtaaagaatt accaggacta gcagcaatca acgataaata aacgaccaag
    94141 tttgctcaat tctgacgagt aatcgaacaa aaggtgaagg gagttttcat gactccctag
    94201 ccatttttca ataaattaag gagtgtgttc ctcaatgcgt aaacctatta tcgcaggtaa
    94261 ctggaaaatg aacaaaactg catcagaagc aaaagaattt gctgaagcag taaaaaacaa
    94321 aatcccttca aatgacaaag ttgattcagt catcggatct cctgcattat tcttacaaga
    94381 attaatgaca tcagctgaag gtacagaact aaaaatctca gcacaaaact gctactggga
    94441 aaactcaggt gcgttcactg gtgaaacttc accagcagct cttgctgatc taggtgttca
    94501 ttatgtgatc atcggacatt cagaacgtcg tgaatatttc catgaaacag acgaagacat
    94561 caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca ccaatcctat gctgcggcga
    94621 atctttagaa acctatgaag caggcaaaac tgctgaatgg atcgaaggac aaattacagc
    94681 tggtttagct gatctttcag ctgaacaggt gtcaaacatg gttattgctt atgaaccaat
    94741 ctgggcaatc ggtactggta aatcagctga cgcacaaatc gctgacgaaa tttgtggagt
    94801 tgtacgtcaa acagttgaaa aactttatgg aaaagaagta tcagaagcag ttcgtatcca
    94861 atacggcggt tctgtaaaac cagaaaatat tgctgaatac atggcaaaag aaaatgttga
    94921 cggtgcttta gtcggtggcg caagcttgca agcagattca ttcttgtcat tgttagacgc
    94981 tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa tgtttgcact aatgagcaaa
    95041 attaactaaa atcgtatatg agggaaatcc cttaggaaaa aacaaactca aaggagagac
    95101 aaaacatgtc aattattact gatgtttacg ctcgcgagat cttagactca cgtggtaacc
    95161 caacaatcga agtagaagta tacacagaaa gcggagcttt tggccgcgga atggttcctt
    95221 caggtgcttc aactggtgaa tacgaagcag ttgaattacg tgacggagac aaagctcgtt
    95281 atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa caacatcatt gctgaagcaa
    95341 tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa agctatgatc gctttagacg
    95401 gaactcctaa caaaggtaaa ttaggtgcga acgctatttt aggtgtttct atcgctgttg
    95461 cacgtgcagc tgctgactac ctagaagtac ctttatacca ctacctaggc ggattcaaca
    95521 caaaagtatt gccaacacca atgatgaaca tcatcaacgg cggatcacat gctgataact
    95581 caatcgactt ccaagaattc atgatcatgc ctgttggcgc tccaacattc aaagaagctc
    95641 tacgtatggg tgctgaagta ttccacgcat tagcttcaat cttgaaagct cgcggattag
    95701 caacttctgt tggtgacgaa ggtggatttg ctccaaacct tggttcaaac gaagaaggtt
    95761 ttgaagtaat catcgaagca atcgaaaaag ctggctatgt acctggtaaa gacgttgttc
    95821 ttgctatgga tgctgcttct tcagaattct acgacaaaga aaaaggtgtt tacgtactag
    95881 ctgactcagg cgaaggcgaa aaaacaactg acgaaatgat caaattctac gaagaattag
    95941 tttctaaata tccaatcatc tcaatcgaag atggattaga cgaaaacgac tgggacggat
    96001 tcaagaaatt aactgacgta ttaggcgaca aagttcaatt agttggtgac gacttgttcg
    96061 taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg aattgctaac tcaatcctta
    96121 tcaaagtgaa ccaaatcggt acattaacag aaactttcga agctatcgaa atggctaaag
    96181 aagctggcta cacagcagtt gtatctcacc gttctggtga aacagaagat tcaacaatct
    96241 ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac tggttctcta tcacgtactg
    96301 accgtattgc taaatacaac caattactac gtatcgaaga ccaacttggt gaagttgcag
    96361 aatacaaagg tttgaaatct ttctacaact taaaaaacaa ataattcttt tctaatgaag
    96421 atacatgatc gactattgaa agatagtcga gtatgatcac ttagttaagt aatcgaactc
    96481 tctacttgct gaaatatcag caggtagaga gtttttttgc aactagcttc tgtatatgat
    96541 gtttacaaag aatggtacaa gaaaagatca tccttgaaaa aggaaagcta acaataacta
    96601 gcatcatata agagctttta aggatagaac agtagaatag gaatctatgg gcaagtcctc
    96661 tcgtataaat a
//
LOCUS       DAFELK010000004        92332 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFELK010000004
VERSION     DAFELK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 92332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.004"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..1388)
                     /locus_tag="LP433_000391"
     CDS             complement(<1..1388)
                     /locus_tag="LP433_000391"
                     /inference="COORDINATES: protein
                     motif:HMM:NF014437.1,HMM:TIGR00826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2004584.1"
                     /translation="MSNKEEAKSIINFVGGKENIAALTHCVTRLRFALRDDTKVDKAG
                     LENLEDVKGTFNANGQFQVVIGPKVADIYEEVISQSGLSGANKEDVKKVAAELNLNWF
                     QRAVKILGDVFVPILPAIVTAGLLMGLNNLLTNPGIFFEQSLIEVYPNIADVADMINL
                     IANTSFQFLPALITWSTVKYFKGNPLLGIVLGLVFVHPDLMNAWNYGQAVTTGDIPHW
                     TIFGLSISKIGLQAQVLPALVSGYVLAKTELFLKKRVPETIQLLVVAPVAILFTSVIT
                     FIIIAPITIAIGNTIVAGIVWLFQKVPFIGGFAYGIGLAPLVVTGMHHAFLPVHIQLM
                     ANGGDYIWPIGVMSSLAQGSAAIAMNFLIQNKKLKGVGLAAGLSAYMGITEPAMFGVN
                     LKYKFPFVVSILTSGIIGGFMASQHVIATSVGISGIPGFLSIPFEFWPIFFICMLASC
                     VVSFGATYLYGK"
     gene            complement(1381..1935)
                     /locus_tag="LP433_000392"
     CDS             complement(1381..1935)
                     /locus_tag="LP433_000392"
                     /inference="COORDINATES: protein motif:HMM:NF025668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III-like domain-contianing
                     protein"
                     /protein_id="HBL2004585.1"
                     /translation="MDVLCGKINPAGKLTITIPRHLGQIPIYYNYFNTGRPYSSEKFN
                     TTKYLDVSNEPQFPFGYGLSYTTFSMSPISIKEKGKNCLKVTTTVSNKGSRDGYEVVQ
                     LYIGAQYGRYIRPTKDLVAYKKVFVKSGDSVTVSFELTNKDFKYYDEEFNEIIDDGAY
                     WIMVGNDSSQALTNKEEIEVRINE"
     gene            complement(2836..5985)
                     /locus_tag="LP433_000393"
     CDS             complement(2836..5985)
                     /locus_tag="LP433_000393"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HBL2004586.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(5998..7215)
                     /locus_tag="LP433_000394"
     CDS             complement(5998..7215)
                     /locus_tag="LP433_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBL2004587.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWE
                     ERKLGELGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIER
                     KKWKPIKDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFE
                     TINLPRYSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLL
                     KETKKSFLQKMFV"
     gene            complement(7205..8800)
                     /locus_tag="LP433_000395"
     CDS             complement(7205..8800)
                     /locus_tag="LP433_000395"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL2004588.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            complement(9310..10092)
                     /locus_tag="LP433_000396"
     CDS             complement(9310..10092)
                     /locus_tag="LP433_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004589.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(10157..10993)
                     /locus_tag="LP433_000397"
     CDS             complement(10157..10993)
                     /locus_tag="LP433_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2004590.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(11011..12420)
                     /locus_tag="LP433_000398"
     CDS             complement(11011..12420)
                     /locus_tag="LP433_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2004591.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(12434..14257)
                     /locus_tag="LP433_000399"
     CDS             complement(12434..14257)
                     /locus_tag="LP433_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2004592.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(15100..15426)
                     /locus_tag="LP433_000400"
     CDS             complement(15100..15426)
                     /locus_tag="LP433_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004593.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(15472..15834)
                     /locus_tag="LP433_000401"
     CDS             complement(15472..15834)
                     /locus_tag="LP433_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBL2004594.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(15871..16086)
                     /locus_tag="LP433_000402"
     CDS             complement(15871..16086)
                     /locus_tag="LP433_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2004595.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            16213..16548
                     /locus_tag="LP433_000403"
     CDS             16213..16548
                     /locus_tag="LP433_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2004596.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVNYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(16624..18621)
                     /locus_tag="LP433_000404"
     CDS             complement(16624..18621)
                     /locus_tag="LP433_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004597.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(18719..18994)
                     /locus_tag="LP433_000405"
     CDS             complement(18719..18994)
                     /locus_tag="LP433_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004598.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            19226..19960
                     /locus_tag="LP433_000406"
     CDS             19226..19960
                     /locus_tag="LP433_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2004599.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEKFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            19999..21141
                     /locus_tag="LP433_000407"
     CDS             19999..21141
                     /locus_tag="LP433_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2004600.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(21236..22627)
                     /gene="sufB"
                     /locus_tag="LP433_000408"
     CDS             complement(21236..22627)
                     /gene="sufB"
                     /locus_tag="LP433_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBL2004601.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKAVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(22632..23102)
                     /locus_tag="LP433_000409"
     CDS             complement(22632..23102)
                     /locus_tag="LP433_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBL2004602.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(23089..24324)
                     /locus_tag="LP433_000410"
     CDS             complement(23089..24324)
                     /locus_tag="LP433_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL2004603.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(24321..25607)
                     /gene="sufD"
                     /locus_tag="LP433_000411"
     CDS             complement(24321..25607)
                     /gene="sufD"
                     /locus_tag="LP433_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBL2004604.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(25620..26393)
                     /gene="sufC"
                     /locus_tag="LP433_000412"
     CDS             complement(25620..26393)
                     /gene="sufC"
                     /locus_tag="LP433_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBL2004605.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(26590..27438)
                     /locus_tag="LP433_000413"
     CDS             complement(26590..27438)
                     /locus_tag="LP433_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL2004606.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(27462..28148)
                     /locus_tag="LP433_000414"
     CDS             complement(27462..28148)
                     /locus_tag="LP433_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004607.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(28141..29175)
                     /locus_tag="LP433_000415"
     CDS             complement(28141..29175)
                     /locus_tag="LP433_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2004608.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(29238..29494)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(29570..29908)
                     /locus_tag="LP433_000416"
     CDS             complement(29570..29908)
                     /locus_tag="LP433_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBL2004609.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(29910..30266)
                     /locus_tag="LP433_000417"
     CDS             complement(29910..30266)
                     /locus_tag="LP433_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBL2004610.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(30272..31459)
                     /locus_tag="LP433_000418"
     CDS             complement(30272..31459)
                     /locus_tag="LP433_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL2004611.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(31650..32495)
                     /locus_tag="LP433_000419"
     CDS             complement(31650..32495)
                     /locus_tag="LP433_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2004612.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            32729..33694
                     /locus_tag="LP433_000420"
     CDS             32729..33694
                     /locus_tag="LP433_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBL2004613.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            34071..35114
                     /locus_tag="LP433_000421"
     CDS             34071..35114
                     /locus_tag="LP433_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBL2004614.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(35176..35640)
                     /locus_tag="LP433_000422"
     CDS             complement(35176..35640)
                     /locus_tag="LP433_000422"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBL2004615.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            35886..36833
                     /locus_tag="LP433_000423"
     CDS             35886..36833
                     /locus_tag="LP433_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2004616.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(37044..39116)
                     /locus_tag="LP433_000424"
     CDS             complement(37044..39116)
                     /locus_tag="LP433_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL2004617.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(39049..39426)
                     /locus_tag="LP433_000425"
     CDS             complement(39049..39426)
                     /locus_tag="LP433_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBL2004618.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(39555..40133)
                     /locus_tag="LP433_000426"
     CDS             complement(39555..40133)
                     /locus_tag="LP433_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2004619.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            40265..41557
                     /locus_tag="LP433_000427"
     CDS             40265..41557
                     /locus_tag="LP433_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL2004620.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(41617..42735)
                     /locus_tag="LP433_000428"
     CDS             complement(41617..42735)
                     /locus_tag="LP433_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBL2004621.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(42749..44170)
                     /gene="arcD"
                     /locus_tag="LP433_000429"
     CDS             complement(42749..44170)
                     /gene="arcD"
                     /locus_tag="LP433_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBL2004622.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(44416..45537)
                     /gene="mnmA"
                     /locus_tag="LP433_000430"
     CDS             complement(44416..45537)
                     /gene="mnmA"
                     /locus_tag="LP433_000430"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBL2004623.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLIYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            45941..46540
                     /locus_tag="LP433_000431"
     CDS             45941..46540
                     /locus_tag="LP433_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBL2004624.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(46678..47964)
                     /gene="efmA"
                     /locus_tag="LP433_000432"
     CDS             complement(46678..47964)
                     /gene="efmA"
                     /locus_tag="LP433_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBL2004625.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(48235..48579)
                     /locus_tag="LP433_000433"
     CDS             complement(48235..48579)
                     /locus_tag="LP433_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBL2004626.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(48716..49861)
                     /locus_tag="LP433_000434"
     CDS             complement(48716..49861)
                     /locus_tag="LP433_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL2004627.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(50041..51015)
                     /locus_tag="LP433_000435"
     CDS             complement(50041..51015)
                     /locus_tag="LP433_000435"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL2004628.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(51095..51970)
                     /locus_tag="LP433_000436"
     CDS             complement(51095..51970)
                     /locus_tag="LP433_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBL2004629.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            52100..54007
                     /locus_tag="LP433_000437"
     CDS             52100..54007
                     /locus_tag="LP433_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBL2004630.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(54548..57826)
                     /locus_tag="LP433_000438"
     CDS             complement(54548..57826)
                     /locus_tag="LP433_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBL2004631.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(58097..58642)
                     /locus_tag="LP433_000439"
     CDS             complement(58097..58642)
                     /locus_tag="LP433_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2004632.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(58654..59346)
                     /locus_tag="LP433_000440"
     CDS             complement(58654..59346)
                     /locus_tag="LP433_000440"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBL2004633.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(59365..59649)
                     /locus_tag="LP433_000441"
     CDS             complement(59365..59649)
                     /locus_tag="LP433_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004634.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(59662..60225)
                     /locus_tag="LP433_000442"
     CDS             complement(59662..60225)
                     /locus_tag="LP433_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL2004635.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            60453..61115
                     /locus_tag="LP433_000443"
     CDS             60453..61115
                     /locus_tag="LP433_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBL2004636.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            61239..62435
                     /locus_tag="LP433_000444"
     CDS             61239..62435
                     /locus_tag="LP433_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBL2004637.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(62536..63912)
                     /locus_tag="LP433_000445"
     CDS             complement(62536..63912)
                     /locus_tag="LP433_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2004638.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(63949..64815)
                     /locus_tag="LP433_000446"
     CDS             complement(63949..64815)
                     /locus_tag="LP433_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBL2004639.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(64904..65929)
                     /locus_tag="LP433_000447"
     CDS             complement(64904..65929)
                     /locus_tag="LP433_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2004640.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIPKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(65947..66621)
                     /locus_tag="LP433_000448"
     CDS             complement(65947..66621)
                     /locus_tag="LP433_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2004641.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(66805..67698)
                     /locus_tag="LP433_000449"
     CDS             complement(66805..67698)
                     /locus_tag="LP433_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2004642.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(67772..69469)
                     /locus_tag="LP433_000450"
     CDS             complement(67772..69469)
                     /locus_tag="LP433_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2004643.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(69462..70775)
                     /locus_tag="LP433_000451"
     CDS             complement(69462..70775)
                     /locus_tag="LP433_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL2004644.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(70775..74293)
                     /locus_tag="LP433_000452"
     CDS             complement(70775..74293)
                     /locus_tag="LP433_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL2004645.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(74586..75044)
                     /locus_tag="LP433_000453"
     CDS             complement(74586..75044)
                     /locus_tag="LP433_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2004646.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(75341..75859)
                     /locus_tag="LP433_000454"
     CDS             complement(75341..75859)
                     /locus_tag="LP433_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL2004647.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(75861..76478)
                     /locus_tag="LP433_000455"
     CDS             complement(75861..76478)
                     /locus_tag="LP433_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL2004648.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(76475..77329)
                     /locus_tag="LP433_000456"
     CDS             complement(76475..77329)
                     /locus_tag="LP433_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2004649.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(77326..78237)
                     /locus_tag="LP433_000457"
     CDS             complement(77326..78237)
                     /locus_tag="LP433_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2004650.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(78278..79612)
                     /locus_tag="LP433_000458"
     CDS             complement(78278..79612)
                     /locus_tag="LP433_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2004651.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            79820..80650
                     /locus_tag="LP433_000459"
     CDS             79820..80650
                     /locus_tag="LP433_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBL2004652.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(80894..81212)
                     /locus_tag="LP433_000460"
                     /pseudo
     CDS             complement(80894..81212)
                     /locus_tag="LP433_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(81334..81528)
                     /locus_tag="LP433_000461"
     CDS             complement(81334..81528)
                     /locus_tag="LP433_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004653.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(82033..82218)
                     /locus_tag="LP433_000462"
     CDS             complement(82033..82218)
                     /locus_tag="LP433_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004654.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(83068..83409)
                     /locus_tag="LP433_000463"
     CDS             complement(83068..83409)
                     /locus_tag="LP433_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2004655.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(83409..83639)
                     /locus_tag="LP433_000464"
     CDS             complement(83409..83639)
                     /locus_tag="LP433_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2004656.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            83926..84264
                     /locus_tag="LP433_000465"
     CDS             83926..84264
                     /locus_tag="LP433_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004657.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(84469..84708)
                     /locus_tag="LP433_000466"
     CDS             complement(84469..84708)
                     /locus_tag="LP433_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL2004658.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(84684..85031)
                     /locus_tag="LP433_000467"
     CDS             complement(84684..85031)
                     /locus_tag="LP433_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL2004659.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(85763..86344)
                     /locus_tag="LP433_000468"
     CDS             complement(85763..86344)
                     /locus_tag="LP433_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2004660.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(86527..87153)
                     /locus_tag="LP433_000469"
     CDS             complement(86527..87153)
                     /locus_tag="LP433_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2004661.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(87175..88506)
                     /locus_tag="LP433_000470"
     CDS             complement(87175..88506)
                     /locus_tag="LP433_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBL2004662.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(88661..89062)
                     /locus_tag="LP433_000471"
     CDS             complement(88661..89062)
                     /locus_tag="LP433_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL2004663.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(89148..89354)
                     /locus_tag="LP433_000472"
     CDS             complement(89148..89354)
                     /locus_tag="LP433_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004664.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(89449..90951)
                     /locus_tag="LP433_000473"
     CDS             complement(89449..90951)
                     /locus_tag="LP433_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBL2004665.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(90969..91424)
                     /gene="argR"
                     /locus_tag="LP433_000474"
     CDS             complement(90969..91424)
                     /gene="argR"
                     /locus_tag="LP433_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL2004666.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(91522..92139)
                     /locus_tag="LP433_000475"
     CDS             complement(91522..92139)
                     /locus_tag="LP433_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBL2004667.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
BASE COUNT        26697 a        19509 c        15902 g        30224 t
ORIGIN      
        1 tttttcccgt aaaggtaagt tgctccaaat gagacgacac aacttgctag catacaaata
       61 aagaatattg gccagaattc aaacggaata gacaagaaac caggaattcc actgatacca
      121 acagaagttg caatgacgtg ttgtgacgcc ataaatcctc caattattcc agaggtcaga
      181 atggaaacca cgaatgggaa tttatacttt agattaaccc cgaacattgc tggctcagtg
      241 atacccatat aagcagacaa accggcagcc agtccaacac ctttcaactt tttattttgg
      301 attaagaaat tcattgcaat agcagcagaa ccttgtgcca aacttgacat gactccaata
      361 ggccaaatat aatctccacc gttcgccatc aattgaatat gaactggtaa aaacgcatga
      421 tgcatccctg tcacgactaa tggcgcaaga ccaataccat aagcaaatcc gccaataaat
      481 ggaacttttt ggaataacca tacaatacct gcgacaatcg tattaccaat agcaattgta
      541 atcggcgcta taataataaa tgttataaca ctagtaaaaa gaattgcaac tggtgcaaca
      601 accaacagtt ggattgtttc aggcacacgc tttttcaaga atagctctgt tttagctaac
      661 acatagccgg aaactagagc tggcaatact tgtgcttgta gtcctatctt agagatggac
      721 aatccaaaga ttgtccaatg tggaatatct cccgtggtta ctgcttgccc gtaattccag
      781 gcattcatca aatctgggtg tacaaagact agacctaaca caatcccaag aagaggattt
      841 cctttaaagt attttacagt tgaccatgtt attaacgcag gcagaaattg aaaggaagtg
      901 tttgcgataa gatttatcat atcagcgaca tcagcaatat taggatatac ttcaatgagt
      961 gactgctcaa aaaagattcc tgggtttgtt aataaattat tcagtcccat cagtaaacca
     1021 gctgtaacga tcgctggtaa aatcggcaca aatacatcac ccaatatttt aactgcacgt
     1081 tgaaaccaat tcaaattcaa ctcagccgct acttttttaa cgtcttcttt gtttgcccca
     1141 ctcagcccag attggcttat aacctcttca tagatatctg ctactttagg accgataaca
     1201 acttgaaact gtccattagc attgaaggta cccttcacat cttccaggtt ttccaatcct
     1261 gccttatcaa ctttagtgtc atctcgcaag gcaaacctca gacgtgtcac acagtgagtc
     1321 agtgctgcaa tattctcttt tccaccaaca aagttaatga ttgatttagc ttcttcttta
     1381 ttactcatta attcttacct ctatttcttc tttattagtt aatgcttgag atgaatcatt
     1441 gcctaccatg atccaataag caccatcatc tataatttcg ttgaactctt catcataata
     1501 cttaaaatct ttgtttgtaa gttcaaaaga aacagtcaca ctatcccctg acttaacaaa
     1561 aaccttcttg taggctacca agtcttttgt tggtcttata taacgaccat attgagctcc
     1621 aatatatagt tgaacaacct cataaccatc tctacttcct ttatttgaaa cggtagtagt
     1681 caccttcaaa cagttcttac ccttctcttt aatgctaatt ggtgacatag aaaaagtggt
     1741 ataactcaac ccatacccaa agggaaattg tggttcattg gatacatcta agtatttggt
     1801 cgtattaaac ttttcacttg aatacggtct accagtattg aaataattat aataaatagg
     1861 gatttgtcct aaatgtctcg gaattgttat tgtaagcttt ccggctgggt ttattttgcc
     1921 acaaaggacg tccaaaatag cattgccagc ctctgctcct agatgccaag cctcaactaa
     1981 tcccttacat atagattttt aaattacaca ctagtttaaa ctaaaacaaa caaggaaaaa
     2041 cttaccattt aatcaaaaaa ttagctcata tgaatatatt agaatgtaaa ttagactggt
     2101 caaaatctgg tcaaaaaaga ggacgaatac aggtagtcct cttttttgtt attttgatat
     2161 tctaaatcat tttttattgg attattccct tgttcgatat agacccaaat tgatctatca
     2221 ataattatca aactgagtca tatagagaca aaaatttcaa aaatgacctg ttaaatggtc
     2281 atcgaatatc atttaaaatc aatacgacgg agtcagacac ggagtcaaaa caagcccgct
     2341 gagagtaaaa aatatacagt cccataggta aagtgccaca ggactgtata tttttttatt
     2401 tgagattacc tgaaatgatt ccatttaatt tttatctcat tttttcctac tagttagtat
     2461 caaatactct cctattttct caataaacta ttttgggtta catggtatct gaaacagcta
     2521 aaaccttgtc attatagcaa aaaatcactt tatctccgtt tcatttcaga tacatttcac
     2581 ttaagcggat tccaaaaaaa caaaagaaaa aggaacccct agttagccta tgctttttat
     2641 tggttcctct caaaacacgg tcatataaca acggggtggg gtaaatgaat gaaaaaggtg
     2701 gaggaaacat tattcaatag ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa
     2761 gacatctatc cctattttct acacttccac ttgactacca tctttgaatc gtacaatttt
     2821 cttaactctt ctcgtttacc tcaattcatt ctcaagtgga atcaactcat catctaacat
     2881 tttacgccat gctcgcttca tttcttgtgg gtatttaaat ggcttcgctt ctggatgttt
     2941 ggctttatat ccttcgtaat ccttactgtt gataattgct ttcatattag gaattggatc
     3001 ttcacctggt agatattgca gattagaagc atgtaattct ttctcagaaa caaaccactc
     3061 attggaaaag acatgaatca aatcatcact cgcttgtgta aaatagcgac gtttaatgac
     3121 aaagatatct tcattactat ctaaagtccc cacatcaaat gcatttaaaa tttgtcggta
     3181 aacttctttg actccttctg ttttattcaa tttagccaaa gctttttcaa tttcttctcg
     3241 tgcatctgaa ctattcgcag cataagttcc tagtaattga tcaatataag ttgaatcaat
     3301 atcatacaac ttagtggtat tttcactata aaattcgatc gttgaaaaat cttctccttc
     3361 tttttctggt tcttcctcta ttaatgaacc cttcacggtc tcgtacacgc caatttgttc
     3421 ttccaaaagt tgaatttgat tgttcaaagt tggagatttc accatgtcat cattgtaatc
     3481 gtcataagtc actaacgatt cataagcacg attcaattct tgaaatgctt tgacgtactc
     3541 gatacggatt tcaagtggcg tatgttcatc aatggattcc atggatgaaa cctcttttaa
     3601 cttaccatat gcttgtttga atcttttttt ggattcctga taacttggat aaatcaaacc
     3661 tgattcttct tttgcttttg aatacagttt tgtcgcatcc tcgacattct tctccattgt
     3721 cgctggctta cgaaacgtca caatcaatcc ttttgtctta tcaggatacg tacgattcgt
     3781 acgtgaaaaa gcttggatca atcctgcata ctctagatta cgatccacaa atagggtttg
     3841 aatcgtaggg gcgtcaaaac ctgttaatag acgatccact acaatcgcta aatcgatttg
     3901 tttcccaaat tgtttgaatt ccgctctttt tcgtgccaaa cgattattga tgtctccgtt
     3961 ataacgctca atgtctgcta atgaccagga agtatcataa tactgattat attcctcaat
     4021 aattttttgc atttcttctt gttgggcact tgaatctcgg ctattttctt ctaatgaata
     4081 ggtaatagcg attcgtggaa aatcaggatc ctccatcgtt cgtccttcac gaatgagctg
     4141 attgggaaac tcttttgtta accaatcagg ctctttcgtc atctctttga tggcccgata
     4201 atactttttg gccatgtcaa tggaactcgt ggttaagatt gcagatttcg ttggcctgcc
     4261 atttcgaaaa tcaaattttg tataggcatt atctggacgg aacattttat gaatgacttt
     4321 ttggatatgt tcatctgctt caaaaacagc tgggtccaaa taactttctt ttttgacagg
     4381 ttccatttga tcaatcatac gattgatctg ttctgatgaa tactctgcat atgtttctac
     4441 ttcttttaat ttccgataga ttttattctc tagtgaagtc ggctccacgg tgttttcatg
     4501 ctctacttga aatcctaaga cagagccatc ttctagcgca ttcttaatgg tataggtatg
     4561 caagacctct ccatactgat catgggttgt acgtgccaat tgccctttgg cttgtttccg
     4621 attctcagga aaaatcggtg tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt
     4681 tttgatttct tccatatttt cagcacttaa cgctcgatga cactcatcta ctacaaacac
     4741 gatatgttgg cccattaatt tttggaagcg attggttcct tttttctctt cttgtttctt
     4801 tgcatatttc aacgccgcat ctagtttttg acgggttgta atgattacaa catttgcatt
     4861 ggcatctgcc aacagggttt cacttaattc tttggcactt cccgttccaa cgatcaagct
     4921 attcgctttg gcgttcccgg aagaaatccc agtattaaat tccgaagcaa attttgtaaa
     4981 ctctgtggtg gtttgattat ctaaatcttt gcggtccact aacatgatcg ttcgatcgat
     5041 ccccgatttt cgtgctaaaa gcttagtaga tacaaaacta gtcaacgtct ttcctgaacc
     5101 agtcgcatgc cacacatacc ctgattgatg tttatttgcg gcaataaaca aggcttgaat
     5161 cgcatgtact tgataaggat gtaacaccat gagggtttta ttgtcttgat cttcactgac
     5221 gattgtataa tccgcaatca aacgatgagc atccgggata tttaacactt gtttacaaaa
     5281 ctcatataag ttttctactt tttcattgtc tttcgttcgc caactaaata aaaacttagg
     5341 gtgcaagtct ttcggtaagg catttgcaaa ataccgagtg gtttgttcat tggaaaccac
     5401 aaacaactgt aaggtcgaaa agatattgtt ccgaaacata ccttcttctg catatttttt
     5461 gatttggtta aatgcctgat aaacaccatc ttttgcagtt acttgtttca gctcgatttg
     5521 gacaatcggt aatccattga ttaataaggt gacgtcaaaa cgtcgatccc gtgcttctat
     5581 gttacttcca cgttttgcaa tttgatggac cacttcataa gtagagattc ctccaccaat
     5641 gtcttgattg gaataaagga taagtgagac agaacccaat tgcgaatctt cccgttcaat
     5701 cgtgatccga gccatcccat tttcaccttt taaccatttc gcagcatcaa atggggtttt
     5761 cgttcgcagc agtaattccg ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc
     5821 attcagttct gcttgattat ttgagataat tttttggcgt aaattgaccc aaaggtcttc
     5881 ttctgatttt agatccggac gatacgtcca ctgattatgc ccttctccaa gtacacgaat
     5941 caactgttct tcgacttctg cttcctcacg gtgactaatt ttcattcttc ttccctccta
     6001 gacaaacatc ttttgtaaga agcttttttt cgtttctttt agtaaatcta acttacgttg
     6061 atgaagagcg atcgtatcat ctagctgttt gaagaaagta ccgatttttt gttgttcatc
     6121 ctttacagga accttaacac tgatattctc aatatcagaa ctgttataag aaggcaatgc
     6181 ccctacttgg gagtatcttg gcaaatttat agtttcaaac aatattttac caaaatagat
     6241 atcccaagta ttattaaata aataagccat ggtattgtta tctattaaga aagggcttgt
     6301 gaccaaacgt tttctattaa gcattattgc tgcgccaact ttagcaaata taatcgctgg
     6361 cacatctttt attggcttcc attttttacg ctcaatttgc tcattagata cataatgatt
     6421 tgcatttctc atttcatact cattaccaat gttattcatg tcggaaactt taaaaaatgg
     6481 agtaccttca gaaccacctt gctcggcatc aggaaatcca attcccgatt gagttttacc
     6541 taattctccc aacttacgct cttcccaatc ttccgtaaaa ccaggaaacc ggatttctgg
     6601 cacttttgct ccgttttcag ggaacatttt ttgtaagaat ccttttttcg tttccttcag
     6661 caaatctaac ttacgctgat gaagagcgat cgtgtcgtca agttgtttga agaaggtgcc
     6721 gattttttgt tgttcttcct cactaggaaa cattgctact atatttttaa acttttttag
     6781 agacagaaca tgttgacctg ttccctctgc ttgaatagat aattgtcgtt ggattccatt
     6841 gttaatacgt cttaagaaga agtcggaatc agcagatttt aaagtaaata caggataaaa
     6901 atagcttata atccctctat caataatgtc attacggtta aacacaaaca catcattatc
     6961 acttcgacta cggaacgtga aatatcctct aggtagtaca aagtaaccaa tattattttc
     7021 tgtagttact tgccgatttg caaaatagtc ttcttgcaaa actatccctt tttgttgaga
     7081 tgaagttagc ataggaaatt gattttgtac acttgtcttt tcaacataat ctacaacgaa
     7141 gtcccccaac ttcctctgtt cccaatcatc tgtaaatcct gggaaacgga tttctggttg
     7201 tgtatcattg ctcatgtttg aacacctcca gcgcaccttg taaccacgct tcattttcag
     7261 gtgttgtttg cagggaagag atagcttcta aaagtttttt ttctagcact tgctgttctt
     7321 gtcgtatctt cttgatgtca tttccgacat gaaccatatc aattggttct tcttcttcga
     7381 aagtatctac atagcgtggg atatttaagt tatagtcatt ttctttgatt tcatcaaagg
     7441 ttgccaaatg agcgtatttc tcgacatctt ttctttcagc gtaggtttcg aggatttttt
     7501 gaatgttttc ttccgatagt ttattttgat ttttcccttt aacaaattca cgactagcat
     7561 caatgaataa tacatctcga gtttgacgat tcttcttcaa cacaatcacc gtcgttggaa
     7621 tcgatgtccc aaagaacaag ttcgcaggca taccgatcac agcataaata ctgccatctt
     7681 ctagtaattt ttgacggatg accccttctg cagcgccacg gaataaaact ccgtgtggta
     7741 agacgatggc catggtacct gtttccttca aatgatagaa cccatgaaga agaaacgcaa
     7801 aatctgcttt ggattttggc gctaatttcc cataacgatt aaaccgagaa tcatctaaga
     7861 aagtcgtatc tgctgaccaa ttagccgaat aaggtgggtt cattactact gcatcaaatg
     7921 tgtaaggttc atctgttggc cagtccttat tcaacgtatc cccattgcgg agattcattt
     7981 cttcggcgtc gacaccatgt aaaatcaagt tcatttttgc tagattgtat gtcgttgtat
     8041 ttagttcttg cccatgatat ttaacgttat ctgggtgtgt taagtagtta cgtacgttta
     8101 acatcaatga acctgaaccc atcgttggat caaaaacact aaagaatcgt cgttcctttt
     8161 gatcgagcgt tacgatttgc gccatcatat cagaaaccat atgaggtgtg taaaattctc
     8221 cggctttctt ccctgcttct gaagcaaatt gactgatcag aaactcatac gcatccccga
     8281 tcacgtcccc atcgtgttct aaaacatcta catcattcaa tttcttgatg acttcggtaa
     8341 tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt tgattggaga tccacatcat
     8401 caaataaccc attaaattga ttgtaggtag atgccaattg cacaaaggct ttgtttagat
     8461 cgttcaattg gaacgttgct tgttttgctt gatccgctaa gacgttgaaa agatactctg
     8521 gtgcaattgc atatcccaaa atatcaacga ttgtggcaat cagatcttct tttgattctt
     8581 catctgaaag taattcacga tacaacattg tttgtttgct tactgtgtca tattcctcta
     8641 aggattcatc tgctaaaaga accacttgtt ccaacaatcg atcggataaa tatttataga
     8701 aaatcagtcc caataaataa tttttatatt ctgacgcatc cattttacta cggagattat
     8761 ctgccgcact aaataatttt tgatttaatt ctgcacccaa aaagatacac tcctatctct
     8821 tatttaaagt tgctatatac cctcttattt tagcataccc ccttttataa aaagcaaaaa
     8881 aaaaaagaaa gaaacttatt cttgctaata aactacgcga aaggagtcta acgttgtttg
     8941 atataactta gactgatcgt taacttattt tttatatttc tacatagtta tctttagaac
     9001 catttcagat acatatgaaa caattacata tgattttttc ataaaaaaac agtactgtct
     9061 agtagtataa aatatacaaa tttcttaaaa attttttcac taaaatcact acctgaaaca
     9121 gtctaaaaca cttatatatc aacgtttaat gaaactatct ccgtttcatt tcagatacaa
     9181 ataaatatag tcgggctcca aatccgaaaa aaaatacccc cagtagctta tcctaagcta
     9241 ctggagatgt ataagtacgg tcatataaca acggggtagg gtaaataaat gaaaaagatg
     9301 gaagaatcat tattcaataa cttttttaaa tacttcgttg taatcagtta cctgtccgtt
     9361 cttaaatacc acagaataat cttttttccc attttcaagt aaccgaagtg gaatgtcttt
     9421 accaacttgc tctgtcactg cattactgat acctgttaga ttagctaata aatctgataa
     9481 agattgagca tctgtagaaa tctctgtatc agtatttatc gtgattcctt tatcttcatt
     9541 tacaagcttc caagtaggtg gtatagctgt gtatgtttcg atgaatgaat caattctttc
     9601 atctatcgtc ttcccagtat ctacttctgt ctcattactc ttagatgaat cgattctttc
     9661 atccatcgtc tgctccgtaa ctgcttctgt ctcattattc tcaccggaaa ctctcttcac
     9721 acccaaactt atatattgtc catctttagt gtgcatagtt aaaattccca cgcttttact
     9781 aataaattca ctataaccag ttctttcaat agagacttca atgtatttca cactatcata
     9841 ctcaaaagaa aaatagacat gtaaaagcat tttgttgttt acatctacat aataatcctt
     9901 tgactctact tgagaccttc ctatacggaa tacagcttta ctgtctgata tctctatacc
     9961 agcatcctta ttattaatct gccaatctcc aagtagctct tctggcaagc tagtagtttc
    10021 ttgtgaacac tttaccactt cactggtaga ggtcgaaaca ttcacctccg cactgttaga
    10081 agaattttcc aaggaatcag gagccttagc acaaccaaca agtctttata tattgtgcag
    10141 ccgatatttt cttcattcag tacacccttg aaatatgcag tgttagataa agcagttcgt
    10201 cctgatttgc tgaggcaccc atctcttctt gaacgtactc cttgattttc aaggccgccc
    10261 gatactcttt cggaaaacgc tgcttcactg aagccagcaa aaaatcatcc ttctccggca
    10321 actcttcctt cttaatcatt cgggcaataa aaaactgtaa atgcgtcaca aatcttaagt
    10381 aaagcatcga atctttatca accttttttt cgggaaacag atatcctagc atagccaaga
    10441 tatcctttag tgctcttacc gagagcatgg tttcttccat atttgcttgt tcactttggg
    10501 catttacaat gtgaaacgca atgtttccag cctcctcttc tggcaactga acattcattt
    10561 ttttgttgat caattggata gcatagcagc cgatctcaaa ttcttttggg taatactttt
    10621 gaatttcaat cagcaggcga ttttgaaaaa caatgccttt ttgactgcgt tcaatggcat
    10681 gcttcaagtg atcaaccaag gtaaaaaata gacttttatt cagcttaaag tcaaacttgg
    10741 cgttggcata atcgataatt cgcttgacgc aaataattag atcatccgga gcagcctcaa
    10801 acagtttaat gtaatccttt tttagagcat cagaaagtga atctaattta aatacttttt
    10861 ggattttgtc agccggaacc aaatcgcctt tctttagttg aaatccaatc cctttcccca
    10921 tcaaaattac ttctttgcct tgcttatcta agcaaagaat taaactgttg tttaacgttt
    10981 taattactct cattagattc accgttctct ctaagctaag ccatttcttg cgattacttt
    11041 ttgataccaa aagaagcttt ctttttttat tcgttttaat tctttaagat tctcatcggt
    11101 tcggtcaaca tatataaaac cataacgctt attgaagcct tgatgggtac taacaacatc
    11161 aatcgctgac caaggtaaat aaccaaaaac atctacacca tctgttaaag ctgcttgaat
    11221 agccagaata tgtttggcta gataatcaat tcgatcctgg tcattaattc gtctatcttc
    11281 ctcaactatg tcgggtgccc catagccatt ttcagtaatt aaaataggta aatcatagcg
    11341 atcgtacaat ttcctcaatg ttaatcgtag tccagtaggg tcaactaccc agccatatgg
    11401 cgttttatct acataaggat tttcagctgc ccggtagaca ccttcttctc ccaacatgat
    11461 ctgttgatcc cccgctctag cggaaacatc tgatccgtca tttttgctgg cagcgatggt
    11521 ggcagttgaa taataattaa tcgcaataaa atcgggttta ccggaggata aaattgcctg
    11581 atcctctgcc tcaattttag gatataatcc acgatcattc aaatagtttt caaacaaata
    11641 attgtatttt ccccgaactg ctacatctaa gaaagaccag cctctcaatg tttcccaatt
    11701 atgggctgca attgcatctt ctggactgga ggtagcttga tacatagccg ttaaattgat
    11761 tgctggaccg atttttcctt taagattcaa ctgatgatac aagtgaatta ctctagcttg
    11821 agctaataaa acatggtgat taatttgaaa gagttctttt tttgaaggca gctctccact
    11881 tggtggcaaa ccaatcgctc caggatgaag gatcatcgtg ttttgctcat taattgtcag
    11941 ccaatagttc accttgtcac catactcagt aagcaatacc tgtacatagt ccacaaaata
    12001 atcgatagtt gctcgattta accaaccgcc ctgctcctct agaaaataag gtaaatcgaa
    12061 atggtacatg gtgacaatcg gttcgattcc ctgattcagg cattcatcaa ttacttgatg
    12121 ataaaaagaa attccctttt gattggtttt attattttca atatccataa ttcgcgtcca
    12181 agcgatggaa aagcgaaaag cttttaagcc taattcttta aacagctgta tatcttcttt
    12241 atagtgatgg taaaaatccg aggcaacttc aaaattagct accccttctg tatgctgata
    12301 cttgtcaata atagacggtt gtttcccatc ctcctgatag gcaccctctg cctggtaggc
    12361 actaatggag gcaccccata aaaacttctc tggaaatgct gaaagctgtt tgtattgcac
    12421 aaaaatcctc tccttaacta atttgcatca atggttcgtg ttcctttaag cttccgcttg
    12481 cttcactaat tcctgcgtaa ttttcactgt tggtcactac cacaatcact gtatcatcgt
    12541 agccagcgtt tctaatggca gcgaaatcgg cgttgattaa taattgtcct gctgacacct
    12601 gatctcctgc ttttacaaat acttcaaagg gttccccttt taaattcacg gtgtcgatcc
    12661 ccacatggat caataattca ataccttctt tagaacgtag accaatcgca tgtttagatt
    12721 ctaaaatagt aatgacttct ccctcaacag gtgaataaat gctgttttct tctggatgaa
    12781 tggctacgcc ctttcccaat agtcccttag aaaagacagc atcgttcact tcagaaatag
    12841 gacacacggt tccttttacc ggattttcaa caatgactgc ttcggctatt gccgtttgct
    12901 ctgattcatc agaagtatcg tcaaatccaa ttagataagc aatgataaag gttgcaacaa
    12961 aggcgattac acacgtaata attgcgtgaa caatattcat tggattttct ccaataaagg
    13021 ctggtaaggc tgctaagcca ggggaaacaa aggcatatct gactaaaccg ctcaagccag
    13081 catacaaacc agcaattgca ccaccaatca tggaagcaac taatggtttt ttcagcttca
    13141 aggttactcc atagagtgaa ggctcagtaa ttcccattaa agcagtgatc ccagtggaca
    13201 cagctagctg cttcaactct ttgtttttag ttttcgcggc tacagcaaag gtagcacctg
    13261 attgagcaat attagaagcc agcattcctg gcccattgat catttcagaa cccgtactgc
    13321 tcaattgcat agtagcgatt ggcgtcattg cccaagctgt acccgtaacc accaaaaatg
    13381 gctgcaaacc acccatcaaa aatggaatta accaagctgc tttgccgtta atccattcag
    13441 cccccattgc tataagatcg ttcagcaacg ttccaaacgg tccaatgaca accaacgcta
    13501 aaggccccat aattaaaaat accagcatcg gcttagtaaa gaatttaata aacgaaggcg
    13561 aaattcgatc cgcaaagggc tctacatagg acatgatcca aacagtaaag ataatcggta
    13621 aaactgatcc cgcataatct gcagctaata ccggaattcc tagaaaagaa acggcatcgc
    13681 cagtagaaaa aagctgtgaa atatttggat gaagcaaaat gccagcaaca gtaatcgcca
    13741 aaattgggtt gacatcaaac tttatggctg ccccataggc taatagtact ggcataaaat
    13801 aaaaggctgc atcagcaata gtattcaaaa tgatgtaagt ttgactactg tctgatagta
    13861 caccagtcaa agtcaagacg gccaaaatgg cttttaccat cccggcacct gttatagctg
    13921 gaatcatcgg tgtaaaggtg gtagaaatga cactaatcaa tcttgaaata atactttctt
    13981 gattgtctga agaggggccc tttttaattg aagttcccac ttccttttga atttccttga
    14041 aggctgtttg gacttcattg ccaatcacca cttggtattg tccaccgcta tccaccacac
    14101 taattacacc aagtgttttt tctaaggctt tcgtatcggc tttcctttta tctttgagtt
    14161 caaaacgcag tctggtggca caatgggtta agctgaccac attttctttt cccccaacct
    14221 gttgcaatac atttcttcct acttctctgt aatccattat tctctctcct taaagcagta
    14281 aaaaagacca agtcaaacca cgccccaatc aacattgaag tgttagtttg tcttggtctt
    14341 gcctgcataa tcagtaacat gccaataacg ttattttgct gtaatccaat aatagcacat
    14401 tatgatagcg caatcaacag ggaatttaat tttttatctt ttcgtttgac cgtatagggt
    14461 aatataacag ttagatcaca tcaactaggg tatatctgcg tatacttact gctaaaataa
    14521 gtatatctaa tattaactat accagtaaaa ccattcctac ataaccagcg ggaaattccc
    14581 aaaatcgtga aagcatcaaa aatgcatata acggatcaca caacttcaac aattctgctc
    14641 ttgggaaaaa ttgatgaatt tggtgagtaa aggatggaat aaacagcatt ccaacaatat
    14701 aggcaacaat agtgatactt gtttttttgg taaaaatcag taagcaatag ccaatttcaa
    14761 tcattccgag atataaaggt atcgatagaa tgatttgggc tagtattctt aaaaattaac
    14821 tagcaaatgt ttaaactgat ttatttctaa tctacatgta gtaagtattt caattccacc
    14881 aattatcaat aaaaatacca aacatatcca taataatttt ttctttttca tttcttttat
    14941 attgttataa cagtgaataa cataaaaatt cccgacaatc attgtaatat ttttttgtca
    15001 cctgtattag tatttaattt ataggaaact ataaaaactc cctagtgaat ttacaccttt
    15061 gggagttcct gtttggacgg tatgcataat acatttaaat caatttaaca ttaacacctc
    15121 agcatatggt atctccacat atatacggtc tttctttgga tagtactcaa tatttatgtt
    15181 gatagcactt ccattgtcta atatagcttt agcccggtat gtgttatctc cattttcatg
    15241 agtaatcgtc acatcatcac atgatcgatt taagttgtac tgttcttgta aaatctgtgt
    15301 taccaatggt tttgatgact tctctaatcc agatgtacct gtcatttttg aaaaaataat
    15361 acctataata gccaagacaa caatacctat aatgacaaac ttcttgttca tatttacttt
    15421 attcaacttt ttatctccta tctccaaaat aatttgctct tatccctctt atcagtacat
    15481 tgacatccct aaaagtacac caaagattgc tccagctacc cctgctatca tcaaaatcgt
    15541 acccattttc tcatcttttt ctcgatataa gtagcccata ataacagcaa cagcaccaaa
    15601 tacaacagga ataaatgcta acgatactac catagaaatc caaccaataa tcaaatacag
    15661 cttccctgtc tcttgtccat gtacgatttg ttccttcatt tcattaattg tctgctcagt
    15721 acttttcttt actgtgtctg ttccggttgt ctcatctgtt tcttgtagtg ctccacaaaa
    15781 ctggcaatac ttactttcat ctgttatttc tttgccacat tttctacaat acatgtcttc
    15841 tcctcctaaa atcattcaat tgcttattag ttaactgttt actttattaa atacatcaga
    15901 aaacagctca ttcattggta cacttaatat ctcagaaagc atcttcattt gatagggttt
    15961 aggaatcgtt ctccctgttt gccacgaact tacacattgc tgtgtaacat tcattttttt
    16021 tgctaactcc gtttgagaaa gtcctttttc ttttctgtat cggctgagat tacttacttt
    16081 tttcatgatt ctcccctcct gttttattat atacaacaat atgatgtatt tcaactcata
    16141 aaatataaaa aacttcaaat accattacaa atacaacaac ttgttgtact atactgagat
    16201 gggggtgtat taatgaaaca gaaacaatat gcaaaggtca ttagagaaaa gcgaaaagct
    16261 ctcgggtgga cacaaaaaga attagctgaa aaaatcttct ctacacaaca ggcagtagca
    16321 agatgggaaa attctgtaac agagcctaac ctcgatagct taacagctct ttctagagcc
    16381 ctaggaaccc ctgtaagcca ttttctagac aatgttgtcg taaattatga ggaagagttt
    16441 ttggctctct atcgttctct tagcactgaa gatgcagttc gaacaattga ctatatgaag
    16501 ctattaaaaa ggcaagaaaa tgaacgcaat cagctattga aagattgaaa aataaataac
    16561 ccaccgaact ttaacggtgg gtgtattgag atgaaataag attaagagct atggataacc
    16621 tgtctagttt aatacaattg ggtcttttct cttccttact ctccgtccat catctcttgt
    16681 tacacttgta aattgataca gaggaactat cccagctcct gataatatca attcttttat
    16741 tgtttcatct atccctgccc ctttcgctaa atatattaaa aaactactac ttgctttcac
    16801 attgtatagt ttcttaatat ccttagaagc tcgttcaaga gtgaatcctt gtttaacaaa
    16861 gtagcctctg ttttttatta aagcattttt cacgctgtta tccccaacat tacgtaggcg
    16921 ttcacaaaca gtgttaataa gttctttctc tgtcattaga tatgtccctt gccacgataa
    16981 gccctgtaaa acttcatgtg cttcatctaa aatcaattgt ttttccttgc tgagttctga
    17041 tcgggaattt tgaggaaata ctcttttagc ctctttttcg ttaaaacata tcttaaccca
    17101 ttcataagaa aaatattgat atgtaaaatg aattttttcc agaagtggaa ggatatcttc
    17161 attcaatttt tgaatcacag aagttgcatt aaaaacgtct aatcgataga cattgcttct
    17221 cttatgatta aagtttccta acgctttctc ttcctttaac ctatttaggt attcgagcat
    17281 cttcaaagga acatcttcat catctaattt ttttatcaat cctataaaag tcataagtga
    17341 tagtaactta ttacatttat ctatgtcata agttttacca tagtaagaac tcattttttt
    17401 agctaattgt tcccccgaca aaatacaagt cacactttcc ttactatcat caaaaaaatt
    17461 aacatcagaa agcaagacat catagacacg tcgcatttcc tctagataat tccttattgt
    17521 cctgaaaagt ttgtctttca ttgattcaag agtgtcaaaa agtacttttg attcctcttt
    17581 caattttcga aaatgtgtag gatacaagtc taggttctct aatagccaat taaatgtttc
    17641 tacccgactg tctttcttta aaattagcat cacaactcca ataaaatttt cactgatatc
    17701 acaattactg gaatgacaat aaaaaatgga atgcccagtt ttactggtaa aaatactagc
    17761 agagggatta tgatcgttgt gaaacagaca tcttaagttt ttacttgact taagtaattt
    17821 attcatatca atggttaaca atctttcata aatctcatta aaagacatgt cggaggaatc
    17881 aaacaggcag tctttaaacc actgtttcat ttcttctttg tcgtcatttt ttatcaactt
    17941 aacaaaatcg gtttcattga ctagttcata ctctctccct gaatcacttt gacaattttt
    18001 agaacatgtc atggtaaaat caatcggaag ctcagtaata tctaacatgt tgtcttcatt
    18061 aattattatc actgcatctg acttatatcc tccaaaaaac attctattcg aagcatttac
    18121 attgtcatca cacccgggga tgttcttttt caagtattcg taaacagcaa ccattttacc
    18181 atagtcagta attgcttctt ttaatagaaa gacaatcttg tatttttcta gattttcaga
    18241 gtaccgaata cttttttgta tcgcaaacgc agaattatga actaaattga tagataaaac
    18301 cttttctacg cttaagtatc tactatcatc tttactcaaa tctactacct tccccttctc
    18361 atctttaaca gtgttatcga catccagaat aattactctg gtttccacaa aactctcctt
    18421 gtcattgcct ttattctttg tcttgcttgg aataaatgat tgtgatgaat ttagtatctc
    18481 tacaaactca tctcttgtaa cttctctata gttatctaaa cacctatctc ttacatcagt
    18541 tttttctttt tttgtaactg gcttctctaa taatttttct tgatctacat aaattggaat
    18601 attaatcatt gatgtttcca tttgtgtttc ctccttataa aattctgtta aagactaaaa
    18661 catacagata ataaaaacaa actctttatt actatatgtt ttagtcttat ttgtttactc
    18721 aacctttata ccgttccatg aaactatcaa tatcagattt tttaaatcta atgaccgtat
    18781 caatttttat aacaggtaac ccgtattgag aaacatattt tctaatcgtt cctactgata
    18841 cacctagata ttcacttgcc tgctgatagt ccatatactc tagagtgact ccagaaataa
    18901 tgtcttctag cataggcttt agcactgtaa ttatctcttt cacttgttgt tcaacttgta
    18961 tagaaacaat gctatcaatg atttgtagag acatatttcc ccctcctttc gtgattgctt
    19021 gaacaaattt tctaagaatt atcttcgtat tttttgctca aaataaaagt attttgttat
    19081 taaccgatta atcaaacaaa aaatgattac cagttcatcg acatacacat aatacctcga
    19141 taaaaaaggg gtgtcaacat ctttgtaaaa tttatttaca acaccccttt tttgaggtat
    19201 actaatttta ggaggtgtgg tcaatatgat aaaacgtcca ccaataaatt atttagaacg
    19261 aaaaaagata ctcggaacaa aaataaaagc tataagaaag agtaaaaaat taacacaacc
    19321 agcatttggt cttatgatta acaacggtca attaattgac aaaaaaacta tctacgaatg
    19381 ggagaaggga acctatttac caataccaga gcgattatcc cgaattgctg atttgggaaa
    19441 tatgagtata gaggagttag tttgtggcaa tgtagaagaa tatattttgg gaattattct
    19501 ttatagagat agcattgtac tagatggtat aacatttcca gataaaaacc tgttccagca
    19561 tcttcgtcaa cagttcccac cagtacactc taatttagat acatggctgg atagatattc
    19621 caaattagaa ccagagatgc aagaatttat tgctaacaag acttgtaata aagttaaaaa
    19681 tgaaaaaatt agtcttttca atatcttaaa aatagaagaa ttattcatca atgctattgt
    19741 agaaaaattt gacaataaca ttcttttcct cactagcagt atagaagaac tactagaaag
    19801 aatggtagat gaatggctac ctattcaatt gaaagacatg tcttatcccg aagaagctgt
    19861 gagagaaatt actgataata taaacaagct agaacaaacg atttcatcaa ttgggaaaaa
    19921 atacactaag aaaaaaatga agggaggtga taccatctag tggtaagtac tccttgtaaa
    19981 ctaagaggag atgatttaat ggcaaaaata tcaaagtaca aaaagaaaaa cggtcaagtg
    20041 gcgtggatgt ataaaggaca cattgccacc gatccacgaa ctggtgaaaa aataaatact
    20101 acgagaagag gttttagtag caaacaagaa gctcaaaaag attatgacga gtacagacat
    20161 caaatattat acggtgttaa aaagaaagca cctgatatga catttgaaga cctgtataat
    20221 gaatggataa ctcatcagcg taccagtgtt aaagcttcaa caatcgcaat ctcagtaaga
    20281 tacgcaaata atcaaatact tccagcattt ggtaagctta aactatcgaa tatctctgtc
    20341 ccatattgtc aaaaagtggt agatgaatgg cacagtaaat atgaaagtta cgattatatg
    20401 agaaaacaga ctgcacaaat tttacgctac ggggttgcaa tgcaatatat tgacaataat
    20461 cctatggaaa aaacacttct tccacgaaaa aaagagtatg agaaaaatcg taaattttac
    20521 tcaaaagagg agcttaataa tttactggat gcttttaaag attttggtaa catgaaacaa
    20581 tacgccttct tcagattatt ggcatacaca ggtatgagaa agagtgaagt actcgcttta
    20641 cagtggaaag acatagacac gtttaataaa gaactacatg tcaataaaac tcttgctgta
    20701 gatgaatttg gtaaagttat aattcaatct ccgaaaacaa gagcttctag acgagttatc
    20761 tctttagata ctgagactct ttctatcctc aacaactgga aattacagca aaaagaagag
    20821 tatttaaaac ttggatacaa tactagctct aaagagcaac atgtttttac aacagttaaa
    20881 aacactctat acattccaaa cactgttaat gattggttaa gatatatttt gaaaaaatat
    20941 aacttgcctc gtattacacc tcatgggttt agacatacac atgctagttt attattagaa
    21001 gcaggagaat ctgtcaaggt agttcaacaa cgattagggc atgaaaatag taaagtgaca
    21061 ttagacatct atgcacatat tacaaataat gcacctaaga aaacaggtca agactttgct
    21121 gatatgatgg ctcatcagta aaagagctgg tcaaaatctg gtcatttcta gtatacaggc
    21181 aaaacaaaaa agctagaacc cttatatatc aagggttcta gctcctataa caggtttacc
    21241 caacactgcc ttccatctca taactgatca atcgattgag ttcgactgca tattccattg
    21301 gaagttcttt ggtgaatggt tcaacaaagc ccatgacgat catttcagtt gcttcagatt
    21361 cggtcaggcc tcggctcatc agatagtaga gttgttcttc tgagattttt gagactttgg
    21421 cttcgtgttc taaagagact tggctgttgt ggatctcatt gaatgggatc gtatcggatt
    21481 tcgaccattc gtccatgatg atcgtgtcac attcgatatg agagatcgaa cccgcactgt
    21541 ttttggcaaa ggttacttgt cctcgatagt ttacttctcc gccgtctttt gaaattgatt
    21601 tagagacgat agagctagat gtatttggtg cattgtggat catttttgca cccgtatctt
    21661 ggatttggtt tgctcctgca aaggcgatgg agagcatggt gcctcgtgca ccttttccat
    21721 ctaagtaaac acttgggtat ttcatcgttg tttttgcacc taggtttccg tcgatccatt
    21781 caacggttgc gccttcgtat gcttttgctc gtttggttac taagttgtac acattgtctg
    21841 accagttttg gatcgttgtg taacggcaat acgcatcttt tcttgtaaag atttctacga
    21901 tggcggcatg caggctgtta cttgaataag taggtgccgt acaaccttcg acatagtgga
    21961 tgcttgctcc ttcgtcaaca atgatcagcg tacgttcgaa ttgccccgtg ttttccgcat
    22021 tgatccggaa gtacgtttgt aatggaacat cgactttgac ggcttttggc acgtaaataa
    22081 aggtcccacc tgaccatacg gctgaattca gcgctgctaa tttgttgtcg gttggcggta
    22141 caagttttga aaagtactct ttgaataatt cagggtattc tttcaaagca gagtcagtgt
    22201 cagtaaagac gattcctaac ttttcgaatt catctttcat attatggtac acgacttctg
    22261 attcatattg tgcggaagca ccggctagat aagctcgttc agcttctggt ataccaatct
    22321 tttcaaatgt atctttgatt ttttctggta cgtcttccca gtcacgagcg ggtttgtcac
    22381 ttggtttttg gtaatatttg atggcatcga aatcgatgtc tgaaaggtcg gggccccatg
    22441 tttgcattgg cattttgtta aatgtttcta gagatttcag acggaattca agcatccatt
    22501 ctggttcgcc tttgattctt gacatctcac ggatcacttc ttctgtcaag ccttctcctg
    22561 tactgaaaac cggttcgaca tcatcgtgaa acccgaattt atattcttct aattctggta
    22621 cgcccatgtt ctcactcctc ttccttgtgg taatgatgga aagctgcggt accatcgttt
    22681 tccattgctt ttcctagtgc tttccaggca agtgtcgcac atttgatccg agcgggaaat
    22741 ttagctacac caccaagcat agcagcatcg cctaattggt cgggatcttt gacttctttt
    22801 ccttggacaa gctgtagaaa gtctacagtt aaatgttctg cttcttctat tgattttccg
    22861 atgacggcgt ctgtcatcat cgaggcactt gccgtactga tggagcagcc actgccgtca
    22921 aaggcgatat ttttgatgat tccgtctttt acatcgactt gcaattcgat cacatctcca
    22981 catgtggggt tgttcaattc gatcttgctt gtcgagtcag tcaagcttcc acgatgatgc
    23041 ggatgggaag aatgatccaa gatcacttga cggtataaat tgtctaattt agatagtccc
    23101 atgttggaaa aactcctttg ttgccatgat tgcttcaact aaacggtcgg cgtcttgcgt
    23161 tgtgttgtag aaataaaagc tcgcgcgagc agtcgctgat acttcaaggt acttcaatag
    23221 cggttgcgca caatgatgac ctgctctgac ggctacccct tccatgtcta aagctgtcgc
    23281 gacatcatgg ggatgtaacc catccaaatt gaatgcaacg actcctgtcc gaaaattcgg
    23341 gtcttgtgga ccataaacag tcaatccatc aattgcttgt aattttggca acacataagc
    23401 ggctagttct tcttcatatc gatggatatt gtccataccg agtttttgca aataatcgat
    23461 tgcatggcct aatgcgatag cgccggcgat atttggtgtc cctgcttcga atttccaagg
    23521 tagttctttc catgtactgt cgtataattc gacaaaatcg atcatttcgc caccaaattc
    23581 aacaggttcc atttcttcta accattttcg tttaccatat aaaacaccaa tacctgttgg
    23641 tccgcacatt ttgtgtccgc tgaaagcaaa gaaatcacag tctagtgctt ggacatcaat
    23701 ggccatgtgc ggggcagatt gagcaccatc tactacgatg accccgccgt tttcatggac
    23761 aagttcagct aattcttgaa caggattgaa gacacctaag acattggata catgagcaat
    23821 ggagacgatt ttggttttgt ccgtaatctt tttcgctgca tcctccatat ccaggaagcc
    23881 ttcttctgtt agttcgatat atttcaagac agcacctgtt cgttttgcca actgctgcca
    23941 cgggataaca ttagaatgat gttccatgta agagagcact atctcgtctc ctgctttgat
    24001 atagcggtcg ccgaaggttc tggctaccca attcaagctt gtcgtcgtac cacgagtaaa
    24061 cagcacttct gctgtttctt ttgcatggat gaacgcccgt actttttctc ttgcttgttc
    24121 ataatcatgg gtcgcgcgtt ctgctaacgt atggacaccg cgatgaacat tggcgttatc
    24181 gtgttcgtaa tagtacgcta atgcctggag tacttgtttt ggcttttggg tcgtcgctgc
    24241 attatccaga taaactaaag gttcatcatt gacgtcttga aataagatag gaaaatcatt
    24301 gcgtagcttt ttagcatcga tcatccattc aacttccctt cgattacttc gactaattct
    24361 ttccgaactt gttctacagg gattgctgtt aagacagaac cgaggaatcc tcgaatcact
    24421 aagcgctctg cttcttcttt atgcaatcct ctactcatca gatagtacat ttcttctgga
    24481 tcaactcgtc ctacactggc agcatgtcca gcagttactt cgttttcatc gatcaaaaga
    24541 ataggattcg catcaccacg tgctttatca gaaagcatca agacacgact ttcttgttgg
    24601 gcatctgcac cttttgcccc tttcaagatg tggccgatac cattaaaggt caatgttcct
    24661 ttttctcgga tcactccgtg ttgcaaaata tgcccgatcg tatgaggggc tttattggtt
    24721 actcgtgtat cgattccttg gatttgtctg cccgagctga ttgccacgat tttgacttct
    24781 gcgtgtgcac cttctcctgc taaatctgag tcaaagtcag cgatcacatg accgtcattc
    24841 atgacaccaa ttgcccagtc gacagaagca tctcgtaaaa tgtgcccacg gcgattcata
    24901 taagaagtaa tattttctcc taattgatct acggctgaat atttgatttt tgaaccagct
    24961 ttagcgatga cttccacgat gatattacct gatgattttg ctacttgttc tttggttgtc
    25021 tggaaacgtt ccagataaga aaattcacta tgttcatctg ccacgatcaa cacatgcttg
    25081 aagaagtgct catcggatgc gccatcttga atgaataagg actcgagtgg ttcatcgatc
    25141 acgacatttt taggcacata caggaaaata ccgctgttca taaaagctac atggagtgca
    25201 gtcaattggt cttcgttcat gtttactgct tttttcatat aatattcttg gactagttct
    25261 ggatattcga tcattgcagt gaacaagtcg gtaaaaatga ctcctttttc tgctaattcc
    25321 acaggcagtt gttcaaaaat cgtccatgaa ccttgttgga caagcacagg attgtctttc
    25381 attgcatcaa atgccggaat cgtgcctgtt tcactgatgg tttgtgtttc tttcacatca
    25441 aataacgacc agcgatggaa tttcacccga tcgatatgcg gcaatggcag ttcatctgct
    25501 ttcgctagtg cgtcttgacg gaaggttctc atccaatcag gttcgccttt acttaaagaa
    25561 aaatcattta ccgcgtcaag ataatcgagc cagttttttt ctttcattct tgctccccct
    25621 tacgcttctt cttctttata gtcgattcct aattctttac tgataccagc gtagccttct
    25681 gcttccagac gtttagctag gtcagcattc cctgtcatga ctactcggcc ttccatcatg
    25741 atgtgaacga catcaggtgt gatatagttc aataatcgtt gatagtgggt gatgatcaat
    25801 gcaccgaaat tgtctccgcg catttcattt actcctttag caacgacttt caaagcatcg
    25861 atatccagac ctgaatcgat ttcgtctaaa attgcaaatg taggttctaa catcaacaat
    25921 tgcaggatct cattccgttt cttttctccg ccagaaaaac cttcgttcag ataacgttca
    25981 gccatttctt ctggcatatt tagtaaagcc attttttcat ctaacttttt caaaaatgcc
    26041 ataacagaaa ttttgtcgtt ttcatcacgt ttcgcattga tcgctgcacg catgaattcc
    26101 gcattcgtga tacctggtat ctcacttgga tattgcatag ctaaaaataa gccaagtcgc
    26161 gcacgttcat ctacttccaa gtctaaaaca tttttcccgt caaacaaaat ttcgccttct
    26221 gttacttcat agtttggatt gcccatgata gcggcagata aggtagattt tcctgtgccg
    26281 ttaggtccca tgatggcatg gatttctccg gttttcattg ttaggtttac gcctttaagg
    26341 atttcttttt cctcgatcga cacatgtaga ttttttattt ctaagacaga catgcattat
    26401 acccccaaat tctctttcgt tctcactcat tttagactaa ttgagaatga agcgcaatga
    26461 ccttccttac taaaatcaaa tatcttttat ttattattaa acaattttga tttctaaatt
    26521 agaataggta taaaaaagat gagaaataag ccattacaga cttatttctc atcttttttg
    26581 ttccatacct tattttgcat cagcctttac tggtttaaca gagccgcccc atttgtctgt
    26641 tatccattct tggacttctt tgcggtgaag cacttcaatc agttttttga ttttgtcact
    26701 gtcttcatca cctttacgag tcgcaataat attcacgtaa ggagagttgt ccttttcaag
    26761 caatacggca tcttctaatg gattcaaccc tgcgccgtaa gcgaagtttg cgttgattgc
    26821 aactaggtca ccttcatcat tttggtacgt agaagctaaa agtgatgggt cgatcgtatg
    26881 gttgaacttc aagttcttag ggttttcttc aatatcatcg aatgttgctg tttccagatc
    26941 tactccatct ttgactttga ctaagccagc atcttgtaga attgtgatga tgcgtcccca
    27001 gtctgattca gaatttgaag taatgattgt tgcaccatct tttaattcgg aaacatcttt
    27061 gactttttta gagtacaagc ccattggttc gatgtggaca gcaccggcat tgacaaagtc
    27121 atatcctttt tctttgattt ctttgttcaa ataaggaata tgctggaagt aattggcatc
    27181 aatgtcgcct tcttccaaag attggttcgg taatacatag tcatcgaatt tgacgatttc
    27241 aagatcgatt ccttcatctt tcaataatgg tttcacatgt tccaaaatct ctgcgtgcgg
    27301 tgtcggtgaa gcgccgactt tcaatgtcgt gtcgtctgct ttatttgctg aatctttgct
    27361 gtcgctgttg ttaccgcatg ctgctaatcc tacagtcagc aaaagcgctg ctgcaaatcc
    27421 aaaaattttc tttttcatat cctacatccc cctatatcct attatctttt gtctgttttc
    27481 ttagttaaga aatcaccgat tccttgaacg ataaatacga ttagtaaaat aattaaagtc
    27541 gcaacgaatg tcactgttag attaccacgc tggtagcctt cctgccaagc aagacctcca
    27601 agtccacctg cgccgatcgc gccggccatc gcagtaaatc cgatcatcga gatcgttgta
    27661 actgttaatc cagaaatcaa tgcgggaata ctttcaggta tcaagacctt ccagatgatt
    27721 tcccagtaac ttgctcccat tgcatctgct gcttccagta caccagggct gacttcacga
    27781 aaagcaatct ctactagacg ggcataaaat ggtgctgcgg ataaaacaag agctggaatg
    27841 gctgcttgcg cacctagcat agtgcctacg attgctttag taaatggaat gatcaaaacc
    27901 atcaggatca taaatggcgt tgaccggaaa atattactga tgatcgatac gattccataa
    27961 atgattcgag catacggttt gtttttgcgt ccaatagagt aaaggatcaa tcccaaaact
    28021 aatccgatga tcgtcactaa gaccattgag attaatgtca tatatagtgt atcaaggata
    28081 gcctgattca tcgtttccgg gttgatttgt ttaaaatcta gatatgtttc tgaaaagctt
    28141 ttatccacga tggatcacct caattcctac tccttgttct ttgatgaaca cttctgcttg
    28201 atctaattct ttggtttcac cagtcatcaa gacagtcaat gaaccaaagg aaccttcttt
    28261 cacttgtttg atctttccat acacaacgtt gacatcgatg ttatagcgtc gaatcgcttg
    28321 ggaaatgact ggctcgttgg catttctttc gctaaaggtc aaagttgcca aacggccgct
    28381 tggattttct ttgatgagtt cagctaatag ttctgtcgaa tcagcttctg gttcgatgtc
    28441 ttgttgtaca aagcgtttgg ttacttcttt tttcggttgt ctgaagacag tcaatacgtc
    28501 tccttcttct acgactttcc ccaactccat cacagcgact ttgttgcaga ttttgcggat
    28561 cacattcatt tcatgtgtga tcaagacgat ggtcaaattc aatttcttat tgatcgctaa
    28621 caataagtct aatacttctt ctgttgtttg cgggtccaat gcgctagtag cctcatcaca
    28681 aagcaggatc tcaggatcat ttgccaatgc tcgtgcgata ccgacgcgtt gtttctgtcc
    28741 gccggaaagt tgtgaaggat atgcttgtcc gcgtccttct aacccgacta aacgcaacag
    28801 ttcttctgcc cgttctttac gtttgctctt tggtacgcca gctaattcca gcggcagctg
    28861 gatattttca agtacagttc ttgaccataa caggttgaaa tgctggaaga tcataccgat
    28921 tttctttcgg aatgtacgta attctttgtt ttttaatttt gtaatatctt gatcgtttac
    28981 gatcacttcg ccgctcgtgg gaagctcaag tccattcagg agacggacta atgtactttt
    29041 tcctgcgcca gaatagccga cgattccata aatatcccct ttttcaacgt ttagtgaaac
    29101 gtcattgacg gcttggatgt ttccgttttt cccattgaat gtctttttga cattcgttag
    29161 ttggattaat gacatgccat tcacatcttt ctcttatgat ttttcaaaca aaaaagcctt
    29221 cgccctcttg ccttaagcaa aaggacgaaa gcttgaactt ccgtgttacc accttgattt
    29281 accgttactt cgcaataaca gcctcttcca gtacttggac ttagcttctt tccgtatact
    29341 gtcgcgctgt aacgggcact cccgtagtaa gtttgcttac gctcgcttac tctgctctaa
    29401 gaccatcttc catctcattt tcgttaccca ttttcagcaa acagggctct cttcaaacgt
    29461 ccgtgacatg tactcttctt ttcaaagctt tctcgtttca tataggattg cttatgatta
    29521 tagcaactgg aagaatcagt gtcaactttt ttcaagtgat tttctgattt tataattcgt
    29581 caaattcttt tggatcaaca tctttgaaac ttaagatcca cgcattcatt tcatctgaat
    29641 cattcaagat attgatatct tcaccgattt tatcattaac agaagaaact gtacccgtta
    29701 gcgggctggc aaattcattg accgcttttt ccgcttcaac ttcgatcaga ggttcatctt
    29761 tttttagcga ttgtcctgct tttggcagat tggcaaacgt gatgtctcca agttcttctt
    29821 gcgcttcatt tgtcaaacca acacagtatt cttttccatt aaataagatc caaaggttgt
    29881 cctttttctt caaatgcttg cctgccattt tatatcagtt ctccttcata aattttttca
    29941 ttgaatccaa ttgcaacaag ctggtcctct cgtaagatca gtggtcgctt gatcagcata
    30001 ccatctgtcg ataagacttg gctcgctttt gaagccgtaa actcgcctac ttgatctttc
    30061 agtccaagtt cccgatattt catcccgctt gtgttgaaca ggcgacggat tggtacttga
    30121 ctcgtttcta gccaagtctc aatcgttgag gccttcggta cttctttgat catatcaacg
    30181 gtttgataac taacgccatg ctggtctaac cacgctttgg cttttttgca tgttgaacat
    30241 ttcgggtacc agtaaaaggt gtacaatttt cttacctcct tgaagatctt gcaggtgctt
    30301 cattttggta tctcatcgat aatatcaacc cgataccgat catgttccct aaaatcgagg
    30361 atcctccctg actaatgaaa ggcaatggga tccctgttaa aggaagtaat ccgatatttg
    30421 ctccaatatt ctcaaagaca tggaacagca gcatcatgat caaaccgctt gcgatatagg
    30481 cgtaaaattc attattcgta tcgaaacaca cccgaatcat acgatagatt aaaataaaat
    30541 acaagaaaat gacgaatgca ccaccgataa agccgaagtt ttcaccgata acggtaaaaa
    30601 tcatatcgga ctcacgaaca ggcacataga tattgcttac gttgaatcct ttaccaaaca
    30661 agccaccggt accaattgcc aaaagtcctt gggccggctg ataactcatt cctgacgtat
    30721 catggaaagg gtccagccat gaatcaatac gtgcaaactg ataagatttg aatccaactt
    30781 tataaagcaa gtctcttccg ccttcagtcg taaccaagaa gatcgttcct gctccaacga
    30841 ctactgccaa gattactaca ggtgcgatga tgcgccaaga gattccagac atcaggaaaa
    30901 tcccgccaaa gatcgcaaga aagacaagca tcgttccaaa gtcatcttgg gccatgatca
    30961 atgctaaaac cggtattgtc acgatcaaga gcttcccaat cagccaaaag tccgatttca
    31021 tcgtccgttc ttttacttgc gtattatgtt tagttacgat cagtgccatc atcaagatgt
    31081 acgcaatctt catcaactct gctggctgga aagtaaacgc accgaatcga aaccagtttt
    31141 tagaccctgt tgaagcagct aaattctgat catagaattt gagcaagagt cccattacca
    31201 ctaaccccaa accataaagg taaggagtca gtttccagat ccatttggaa ttcaaatgca
    31261 tgatgacaac gattgctgcc gctccaacta aataccagac aacttgcatc cctacgcctt
    31321 tcaagactgc tggattgttc ggatcatggc taagtgctac atataatgag agcagaccaa
    31381 tcaaacataa cagaaagact ggtaaaatca cgccataatc aatacgatta tcgttcgaag
    31441 cttttaattt tttttccatg tttcatccct tttcttaaaa accatactgc tgattattat
    31501 agcggtccag ttagataatg gaaagtcttt ccatagacat ttgggaaaaa ttaactttcc
    31561 gtttgtgcag ttgcttgagc aaatgcagta caaaagccta ctgcttatct ttagtgtatc
    31621 atagaacttt ttttgataca tgcaattatc taccagctga gattctcctc gctgtgagaa
    31681 gtttctgtgc tttcattgta tcgaaggatc tcttcggcaa tctctagcag ctgatcagaa
    31741 accagattgg ttcgttggat gaaataaaaa tatcgatgga aattcaacgg agtcattggc
    31801 acattttctg gaacagagcg cttagacaaa atcgagcgac cgattccttc cttcagcaac
    31861 gcaacaatta catcgttact tttcacgatc atcttcttat cttggatatt catctcttca
    31921 aaataacgct gcgtgtaatg aaaaacacca gagtttgctt ctcttacaag ccacaatttg
    31981 ctttttgggt ccccagcgat gactagctgg tcttccatca aagagtatct ttgtacgccg
    32041 gaagtctcta atggcttttc gataaaacca aaatcggatt catgtttcgc tacttgttct
    32101 aatgattcat gagaattcgt gatttcgatc tcaaaatgca ctttaggaaa ccttttgatc
    32161 agatgtttca tcaactgagg caaaagatag acagcaaagg tgtgggaagc aacgatccga
    32221 catacttctt cttcattttg ttcattgagc aatttttgct gagtttcttc ccattcttct
    32281 aacaaaacca gtgtccgttc atataataag tcggcttgct tagttggaag catctctttt
    32341 cttccgttac gttgaaaaag atcgatattc aattcccgct ccaactgttt gatttgattc
    32401 gagactgctg gttgagataa aaacagtact tctgctgctc tggaaaaatt tcttgtttca
    32461 tatactgctc gaaaagtcgt taataactta aacatggcac cacttccata actttttatg
    32521 ataattacta taaaaactat ttgatttaaa tatacaaaaa accatctata atagaaatgt
    32581 acaacaaaac agttgctgat ccaactagta acttagatga agacaatcag ctgtctgctt
    32641 gctcgtaatc atacattcct attcatttta caatgtattc gttcatcttg gtactaaaat
    32701 ctattaaata aaaaggagaa tattatatat gaagaacttt ttgaaaatta ttccgatccc
    32761 gatctgcggg ttgatccttg ggttagcttc ccttggaaat ctgtttaaag actatcacca
    32821 tgttgcttta ggcaatctaa ctggcggtat ctctatgatt cttatgatat tcatttttgt
    32881 taaattgttt atcttattcg aacacacgaa acaaacgttg catgatccaa tcatcgcctc
    32941 cgtttcacca acttttacga tgtcactcat ggttatttgt acttattttg tttcatatga
    33001 aagtattgca ccaattgtca aattcatttg gctgtgcgct gttatcttcc aagtgatcct
    33061 tgtcttttat ttcaattatc accatgttat caaagctgat ctttcaattg aagcaattta
    33121 tccaagctgg tttatcattt acgttggatt tggggtcatc actgtaactg ccgggaactt
    33181 cttcccactt attggaaaaa ttttcttttg gatttcattg atctgctatg cgttcttatt
    33241 gccgatcatc atcaaacgtg tctttttcgt aagaaatatg gctcatccga cacgtccgct
    33301 gattacgatc gttgcagcac ctggttctct ttgcctaaca ggttatctta aaaactttgc
    33361 tgaacctaat ttttatcttg tcgtagcatt gttcgcttta tctcaagtat tgtatttcgt
    33421 tgtgctgtct atgcttccac gtttgttcaa gcttcgtttt tatccaagct atgcagcctt
    33481 tacattcccg cttgttatct ctgcaacagc tatatttact actgttcatt acttcaacag
    33541 tttaggtatc tatagtagcg tattggattt cttaaaagtt gcggaatgtc tgtttgcaag
    33601 tgtagttgtc ttctacgttc ttgctcatta cgtacgtttc ttaattaaag aacatagcaa
    33661 acatggaaaa tttgtttcta aaaaaatcgc ttaataatcg attcaatagg ttgtgaaaaa
    33721 gctgttctgc atcaagtaat aagaacggcc aaacaaaaac agctgttcat gtttttgtac
    33781 tggttgggct tattaccgca gatgcaagct tttgaacacc gtttaccaag aggtcgtaaa
    33841 agaagtggtc agcttcaaga aataagaagg aatttacgaa aattgcttct caaatttttg
    33901 tgaaatttcg gcttatttcc gtagaagcta cttctggaac accgtttatt cgaaacaaga
    33961 ggtcgtacaa gacttttgtc acgacctctt gttcttttgt caaaatactg gtttagtgct
    34021 actatgttcg agtatgcttt tagtatttat tgacgaaagg aaccgatcaa atgaaatcat
    34081 tgtcacatcc aataaaatct gtaaaggatt cagcggtccg cgaaatctta cccggtttac
    34141 tgctttcttt tgccatcgct gccttcagca ggcttcttgc tatttatctg ccacagttag
    34201 gtggagcgac tattgctatt ttattgggta ttttattagg aaatactttt tttaaacagc
    34261 ctgttctagc aatcggcaca aaatttgctg aaagcaaact attagaattc tctgtttttt
    34321 tactaggtgc aactgtcaca gctcaaacga ttgctcaaat tggtgtaaaa ggaattgttt
    34381 ttgtgttact gcaaatgtca gtcactatca tcggtgctta cttgattggt aaaaaactgc
    34441 aattcagcga tacttcttct ttgatgatgg ctggaggaaa cgctgtttgt ggttcttctg
    34501 ctattgcttc aatcgcccct tccatccatg cgaaagagga agaaaaagga cagatcatca
    34561 cactagtcaa tctactgggt actgtgatga tgttgactct cccttttctt ggattacagt
    34621 tgtttggtgg aaatctcatt gaaaaaagtg cacttttggg tggtacactc caatctgttg
    34681 gtcaagtagt cgctggggca agcttacttg acaattctgt tgtcgaattc gccatgctat
    34741 ttaagattct acgtattatg atgctcgttg ttgttgtcta tctgtttgaa aaattcatgc
    34801 acaagaaaca accagctctg tttgaaacgc caactgatac gcagaaaaaa cgaaaattac
    34861 cgcttccttg gtatgtatta gggtttgtga tcttttgttt ggtcaacagc ttgttttctt
    34921 tacctgtagt tattgaccaa tcggcacatt ttatcagcag ctggtttgag atcactgctt
    34981 tagcggcaat tggtctgcgt ttagactttg caaaattcat gaaagaaggt acacgcttct
    35041 tatcttatgg attagctgtc gggcttctcc aaacagtgat ggctttacta tttatttggc
    35101 tgatcaaagt ttagaatgaa catgaaaaaa cagttgtgat tctcgcatgg aacaatgtcc
    35161 gaatcacaac tgtttttaat tttgcagata tccttctaac aacaacaatt ggcgtttgat
    35221 ttcaacccca tctattgcgt ttcccatata tcctgtcagt tttccatttt gcccgatcac
    35281 tcgatgacaa ggaataacga ttggcaatgg attggttcga tttgcctgcc caatcgctcg
    35341 cacagctttc ggactatcaa cagcaacggc tacttcttta tacgttcgga tttctccata
    35401 aggaatggtc gacaaagctt tccagacatt ttgctgaaaa ggcgtacctc tctttataga
    35461 taaaggaaca tcaaattctt ttctttttcc cgcaaaatat tcttcaaact gttcttgtgt
    35521 gcgcgttaaa attcgctgat tcgctgattc gctttctgaa attggctgaa aagatacagc
    35581 agtcaatccg gattcatctg catctaacca taaaaagccg ataggtgtgt gtattttcat
    35641 tttgtttgct cctagtcaat agactggaac ttcctccttt ttctctatcc aaaactactt
    35701 gccaactaat aaaaattgtt cttaaaagtt tgataaaccg aggaaacatg gtaaactaaa
    35761 tacgttagtt tacaaaaaga atacctgttc ttttacgtaa aatcaaattt taaaggtgtt
    35821 atttaaggtt tattaaattt tgaatgtaaa ccatatataa acatacgatt gaaaggatag
    35881 aaacgatgaa agtatcaatt gttgtcccat gttttaatga agaaaaaact gttcctcttt
    35941 tttttgatga ggttgaaaaa ttcaaaggtg cccatgagtt cgaatatttg tttattgacg
    36001 acggatcaaa agacggtacg ttagcagcaa tcaagaagct agcctcagct tatccttatg
    36061 tccgctttgt ctcattttcc agaaattttg ggaaagaagc ggctctgtac gctggattgc
    36121 aagcttctac aggagattta gtgaccgtga tggatgttga tctgcaagat ccgcccgaac
    36181 tgcttcctga gatgatcaac cggatcacta cttctgatat cgattgtgtc ggcacccggc
    36241 gttcgactcg tgaaggcgag cctgcgatac gcagtttctt tgcgaaaaaa ttctaccagt
    36301 tgatcaataa aatcagcgat acagaaatgg tcgatggcgc tcgtgatttc cgcttgatga
    36361 ctcgtcaaat ggtggatgcc gtcctagaat taacagaata caaccgattt tcaaaaggat
    36421 tatttagctg ggtcggattt aaaacagaat atatttctta tgaaaaccgc gaacgtgtgg
    36481 ctggcgaaac atcttggtcc ttctggaaat tattcaacta ctcgattgat ggtatcgtga
    36541 acttctcgga tgcaccgtta acgattgctt catttatcgg cgctttgtct tgtgtcggtt
    36601 ctggtattgc aattttgttc attattttgc gggcattgtt gtttggtgat cctacatcag
    36661 gatggccttc catggtctcg atcttcctgt tcattggtgg aatccaattg ttatgtcttg
    36721 gaatcatcgg gaaatatatt gggaaaatct tcttagaaac gaaacagcgt cctgtttata
    36781 tcataagaga aacagaaaaa gtgaagccaa atgaattgaa gcctcaccaa taatatacgt
    36841 caaatgaagt aaacattttt ttaaatgaaa aaggactgtg acaaaagtct tgtcacagtc
    36901 cttttttccg aataaatggt gttccagaag tagcttcttc ggaaataagc cgaaatttca
    36961 caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct gaccacttct
    37021 atcacaacct ctttcatatc ttattacttc ttcattgctg cttttagtgc tgctgctaat
    37081 gggctttctt ctggttcttc tgcttgtgca tattttttca gcaagcgtcg ttcttcatgt
    37141 ttggtcattt tcttcttctg ctctttttta tcaagcaatt tttctgtcgt tccatcgtat
    37201 ttacaacgga aataagcacc gtttttacct tcgatgattt ccattttccg gtgacattgc
    37261 gggcatcgat gattagagac ttttggatct tttcttctgc ggtagttgca atctgaattg
    37321 gtgcagacat agattttgcc gtcacgtgtg tttttctcgc gcagattggc cccacattct
    37381 gggcatttct tttgggtaat cgagaaatct tgatattctt gtttgcttga tttgatctca
    37441 ttcaccaagc gttttgtttc tttttcgatt ccattcaaga aggttcctgc ttgtttcttt
    37501 cctgcagcaa tagcttcaag gtctttttcc cagctttctg tcaaatctgg tgttactaaa
    37561 gagggattta ccaatactaa taattgctta cctttaggag atacttgcag tccttgaggg
    37621 gtacgttcca tcagttcaga tttgattagt ttctcgataa tctctgcacg cgtagctggg
    37681 gttcccagac tgtatttttc catttgacca agcaagcttg cttctgacaa tggtttaggc
    37741 ggtgcagata gttctttttt gatggcgaaa tcgggattga ttctcattcc tttttcccat
    37801 ttgactgttt ccgtctcagt ttcagtttcg cctttccatc ctgcttggac gacacgattt
    37861 tgccgaaaaa tgaatcgttc tttaccaaat tcaaccgtaa cttttgtttg gctgacttta
    37921 tggggttgag caaacagtcc taaaaaacga gagacaatca tttgatagat ttttcgctct
    37981 tcattactta atttttcata acgtgctctg ttttcagttg gcaaaagtgc atggtgatcg
    38041 gtcactttac tgtcttggaa tacttttgtc tgttggacga tggctccgtt tttcaaatac
    38101 tgcttgacct caggagcaaa gtcgctgact gcttgcaatc gttctttcat cgtacttttc
    38161 atgtcatttg tcagatattt gctgtctgta cgcggataag taacgatctt atgggtctca
    38221 tacaaacttt gtacaagact taatgttttc tttgcagaat agccatagcg ttgattggct
    38281 tctctttgga tctctgttaa atcataaggc aatggcgcag attccgtttt taatttttct
    38341 tggacttctg tgacagttcc tttgcttgta ctgatcaatt gaacaagttt ttgtgcttct
    38401 tcttgtgttt ttaaagcaaa ttgatttttt tgaagcattt tggcttgttc ttttccagct
    38461 tgcaacgtga tcgtgaaata cgtttgtgga cggaactgct cgattttctt ttcttggtct
    38521 ctcactaatg ctagtgtcgg tgtctgcaca cggcctgctg ataaattatc cgcgtacttc
    38581 acagttaagg ctctggtcac attcaatcct accagccagt ccgcttttgc ccgggcaaga
    38641 gcagattcat acaatgcatc atattctttc gcaggtctta gttgcttgaa tccagttttg
    38701 attgctttat ctgtttgaga agagatccat aaccgcttca ctggtttatt gaaatgcaca
    38761 tactctaaga tccagcgagc aacaagttcc ccttctcttc cggcatctgt cgcaatgact
    38821 gcttctgaga catcttttcg ctgagccagc tgcttgattg cttttaattg atgtcctgtt
    38881 ttaggaagtg gtttgattcc tagtttttta gggatcattg gcaacgtgtc catttgccag
    38941 ctctgccatt ccttattcag atcttccggc attttcaatc ctaataaatg accaagggcc
    39001 caagtaacga tcaccttggg tccttcataa taatttttgt gcttttgatt agcaccaagc
    39061 accttgctta ggtctttcgc aacgcttggt ttttccgcta gaattagttg tttcataaaa
    39121 ttcctttctg ctttctactg tgatgggctg atgatttttc aacaacgcaa gtcccttgta
    39181 ttgctgtaaa tcatcgtcac actcttcaca ccagcgctca tctccgtcat tccaaaaggc
    39241 gctgagaaag ttactttttg cattgatata ttcataattt tgatggattt cgttccattg
    39301 tttttcgtac gcttgtcgtg cttcttcgaa agactcgaat gtttcttctt cttcaatatc
    39361 ttcttcccag tcttcaaaaa accaccaagg ctcattgtcc ccgaacatgg taattacttg
    39421 atacatactc gtgctccttc tttcagcttt tctagactca tcttagtcac ttttcaagaa
    39481 agttgcaaga attttctctt ataaaagggt catttaatga acatcttaaa attgttacaa
    39541 atgaatctga ttgtttaagg caaagtagcg ataaagttat tgatcatcca aaaatagctg
    39601 tcttctggat cgattgttgg ttcttttgta aagtatccta aaaaacgtaa ggaaagataa
    39661 ccgtggatca tactacgaag ttccctgctt cgatgaactt tttcttcttt cgttaattga
    39721 aaagcctcaa atatctgcaa aatgatctga ttcgtttcat ggattccatc taataaaaca
    39781 gcttcattgg tatgcggtac actgatcagt aactcataca ctgcttgatt tgaaaaagca
    39841 aaggatcgat aagtttctgc atagatctgc agtgcttcct gaccactttt tcccacaaga
    39901 gcccgtcgca gctggtcatt aagttcctgc agaagtttcg ctgttagcgc tgttttgaca
    39961 tcacgaatat ttttgaaatg gttatacagc gagggagcct tgatatccaa gcgtttggct
    40021 aaatgctgaa aggttatttg ctgaacatcc atctcttctg ctagttctcg aaagcagtcg
    40081 atgattttct cttgagacag atttcttttt ttcatttcca tgtttcctct cataaaataa
    40141 atccttcact ctttcagttt accacgaaaa agaaagagaa aaaagagact ttcattgata
    40201 aactacatat tgtagtttat aataaagagc tgtagatgaa aattttcaga aagaaggagt
    40261 ctaattggct gcaagaataa aggaaaaatt atttaggaaa agagaaactt gggaacaaaa
    40321 cttgtttgtc ttatggtttg gaacatttat ggctggtatc ggatttagtt tagtcatgcc
    40381 ttttatgtca ctttacatag atacgttagg taattatagt acgtcacaat tgaacttttg
    40441 gagcggattg actttttcat ctactttctt ggtgactacg cttatctctc cttggtgggg
    40501 aaaattagcc gaccaaaaag gaagaaaatt gatgctgttg cgtgcttcat taggaatggc
    40561 aatcgtcatt tctttgatgg gttgcgtgac tagtgtgtat caattagtcg cattgcgtct
    40621 gcttcaaggg attttttctg gttatatcag taatgccact gcccttgtcg caactgggac
    40681 gccaaaagaa aaaagtggtc aagttcttgg aaccttagca actggttctg ttacaggaac
    40741 attacttgga ccgcttcttg gcgggatctc tgcttcagcg tttggctatc gccctacctt
    40801 tttcattaca gggatcatct tatttttcgt cttcttgttg agtctgtttt tcgtccatga
    40861 aaaatttgtc ccagtgaaaa aagaaaacat ggtttctgcc aaacagattt tcaaagactt
    40921 gaaatatcca cacgtcgtca tcggtatgtt cgtcacaacg atgatcatcc aagcatccaa
    40981 caattccatt agtccaatca tcagtctgta cattcgccaa ttgctgcatg gacatgggaa
    41041 tgttacgttg atcagcggaa tcattgcttc gatacctggg attgccactt tgatagccgc
    41101 tccaagattt ggtcgcttag gtgacaagat tgggagtgaa agaatacttg cgattggttt
    41161 gggttttgcg attctggttt atatcccaat ggcattcgtc acgaatgttt ggcaattagc
    41221 tgccttacgt tttttgattg gtatctctga tgcttgtctg ctccctgctg tccaagcatt
    41281 gatcacaaaa tattcgcctc atcaagctgc tggacggatc ttcagttata accaatcttt
    41341 ccaagcaact ggtaacgtag tagggcctat gatcggctcc agtgtttcca gtgcatttgg
    41401 ttatcgtggc gtctttcttt cgacttctct tcttgttttg gtcaacttct tgcttgtacg
    41461 acacaataca caagagatcc atcagcaaga aactgcagaa gaaaaagctt caggagtctc
    41521 catagcttca gggcactctc cttctcatag acaataagcg taaatgaaaa acactgcttg
    41581 aacagttgtc acagactgtc cttgcagtgt ttttgtttag gcctgttttt tcaagaactc
    41641 agataagagg aataatccct tttccaaggt ttctttttta caacagtaac ctagtcgggc
    41701 atgcttcggt aaatcaaagg cacttcctgg tactaatagt actcctgttt cttctaataa
    41761 attgatacaa aatgtctggt catcttcttc gatggctaat ttaatgaaag aagtagagac
    41821 gtaattggga gcgacaagtt caactttcgg ttcattggct acccattgtt ttaaaatcac
    41881 aaggttctct gtaatgatct ttttgtttcg cgccaatatt ttttctttat tcttcaatgc
    41941 atgtacagca agatcatctg acaggactcc gccgcaaatc atcgtgtagt ctcgatactt
    42001 tcgaaaaact tctgccaact caggtccagt agctgtccag ccaatacgaa tacctggaat
    42061 ggagtaggtt ttggataggg aattggttgc tatacctttt tcatagacat ctacgatcga
    42121 caagaattca cctttatccg ttaaaggcgc atatacttca tctatcaata catatgcatc
    42181 tactgtacga gcaatttctg cgattttttc taaagttttc cgatctagca atgtgcctgt
    42241 aggattgttt gcactattca aacagatgat ttttgtttca ggtttgacta aggcttctag
    42301 ctgttctaaa tcaaactgcc aatcttcttc ttccttcaaa tgaacaaagt caacagcggc
    42361 acctaaagat ttggggatgt catataattg ctgataagta ggaagcatcg aaacaacatg
    42421 gtctcctgct tccactaacg cgtataaagc taaaagatta gcaccagtcg ctccattcgt
    42481 ttgtaagatg ttttccggat cgacggtttg ataaagagaa gcgacttctt gtttgaaaac
    42541 atctgatcct tcgatccagc catagtccaa tggttcgttt ttgcgttttt cgaaaaattt
    42601 acttacgcta gtcccatcta agccaacgag ttcgtctaat gtcaatgctt cgatcgagct
    42661 ttgtgcaata tcatataccg ctttcttttc ccatttattt agccattctt ctacaccgaa
    42721 atttgcgatt ttcatgtttc tttccccctt atatcttgat ccagcctaca gcaagcaacc
    42781 cgattgaaag cagtgcggcc acacaaatca gcccaatcat tactttttct tttcccgtaa
    42841 tttgatgttt ggtttcacga caagcgatcc agtagaagca aaaaccagga agataggcaa
    42901 tactacataa aaggacataa gaaaatcctg ctaaaatgat gcccatcaat tcaaaaacta
    42961 cagcaatccc accgatcact acttgttttt tgattccttc ttttaaagaa aactggactt
    43021 gatagatccc gacaagtaga taacaaatca aaattgccgc tgtacataaa gaataggcaa
    43081 attgataggc ataatcagta actaagaaag tcaataagaa tagattagtc aagattgcag
    43141 taacaactaa cgaataagtt ggggcatttt ttttattcgt ttttccccaa cctttcggca
    43201 acagaccgtc tcgagccatc aacatcgttg tttctgctgg gagcatcgtc caagacaacc
    43261 aagaaccaat gatcgaaata atcaagccga tattgatcag cgctgctccc caatttccca
    43321 cgattccttt taaaatattt gccatagcag gttgtgaaat agttgctaac tcttcttgag
    43381 ataagacgcc gtatggcaag atcgaagcaa ggatatagat aaacaataaa caaagcagac
    43441 caatgatcga tgcttgctgg gcttctgaac gtttcttcgc gcggttggct aaaacacttg
    43501 cgccttcgat ccctacaaag acccacatca taaccatcaa acaaccttta atctgcaacc
    43561 agatcgttcc ttgctgccct gttccattca ctagattatc agatacgtta ccccaaaaat
    43621 cagcagtgaa tatattcact ttaaatgcga taaatacaaa tattaaaaat aggaataatg
    43681 gcactaattt acagatcgtc acgattgtat tgatgacgct cgctccttca actccattgt
    43741 ttactaataa agtcagaccc caaataaaaa tacttgcaaa taaaatagaa ggaacatttt
    43801 gtccaccttt gaatatcggg aaaaattctc ccatggcgct catcagcatc gttgcaaaag
    43861 caacatttcc cagccacgca gacaaccagt aaccccaacc actgatgaag ccacctaatt
    43921 taccaaatga agcttccgcg taaccgaaaa taccaccatc tagatctgga cgcttttctc
    43981 ctaaatgatt cagcgataat accaaagcta aaataccaat cccaacgatt atccatgaaa
    44041 ggatcgctgg ccctggagct gcagaactag ccagatcact tgtgatccca aacacaccgc
    44101 ttccgattga cgaactgaca accagagcaa ccagtcccca tttgctaata cccgtcgatt
    44161 tcttttccat ttccatcacc ctcacttata aaattgaaca aatcacttgc aaaagattcc
    44221 cttctatttt gcaactgctc ttgcttaaca aaaagcaact ttattcatat tattggatat
    44281 tatgaacttt ttacacaagt atttcaagta taaaatgaat aaaaattaat tttattgcaa
    44341 aaaaacagct atgctatcca aaagaaaagg tgtttctttt gttagccata gctgttttga
    44401 ttcatttaat atcgcttaaa cgtattgtaa aacttttgtt tcttgatatg cgtggtcgat
    44461 caaaccacca cccagacatt ccattccatc ataaaataca actgcttgtc caggagtgat
    44521 tgcacgtaca ggttcgtcga atacgacttc tgcacgatta tcatccaata agcgaactgt
    44581 cacaggaacg tcttgctgac gataacggaa tttcgctgta cacttgaatt cttttggcat
    44641 tggttcattc gtcgtaaagt ggatttcact tgcatccaag cttgtggcat acaatgcagg
    44701 atgatggaac ccttgcccca catataatgt gtttgtcgct agatcttttc ctacaacaaa
    44761 ccagggttct tgcgaatctc ctccgccacc gatccctagt ccttgacgtt gaccaatcgt
    44821 ataatatatc aagccagcat gttgtccttt gacttcacca tcaagagtga ccatatttcc
    44881 tttttttgct ggcagatagt tgctcaaaaa ttgtttgaag ttcttttcac caataaagca
    44941 gattcccgtt gaatcttttt tcttagcagt cgcaaggcct gcgcgttcag caattgcccg
    45001 tacttctgat ttttccatgc cgcctagagg gaacatcgtt tttgaaagct gttcttgtga
    45061 taattggcta aggaagtaag tttgatcttt attattgtct actccacgaa gcatgtggac
    45121 cacgccgttt tcatcgcgag tgacttgcgc ataatgtcca gtagctacat aatcggcgcc
    45181 aagatccatt gcataatcca agaatgcttt gaatttgatt tctttgttgc acatcacgtc
    45241 tgggttaggt gtacgtcctg cgcggtattc ggctaggaaa tattcaaata cacgatccca
    45301 atattctttt tcaaaattca cagagtaata aggaatcccg atttgagcag ctactttcgc
    45361 tacatcctta taatcttccg tggccgtgca tacaccgttt tcgtccgtgt catcccaatt
    45421 tttcatgaat attccgatca cgtcgtatcc ttgttccttt aacaaaagtg ctgttacaga
    45481 tgagtcgaca ccgccgctca tccctacgac aacgcgtgtt ttgctgttgt ctgtcatgat
    45541 atcaccatca tttcaattag attctgaaac atctacgagt tgaaggtcgc aacttttcag
    45601 tattttacat tatacgtcat atttctgaaa atttcatccc ttaattatca agtcgtaaaa
    45661 atactgttct actggaccta ttcagtacac aaacatgata gtcaaccaaa aaatcactca
    45721 tcttttgagc attcgatata aaaaattggc atactcataa aaagggccag cctttcggca
    45781 ataaggaata attttataaa ttgtgaaaaa ctatttttca aaattgcttc ttatcgctta
    45841 aagctgcacg tctcatttac aaccttttct ttttagatgt tatgagttgc tcagataagt
    45901 gattttgttt actctaagaa aaaagggagg caaaagatac atgaattact ttatcagtga
    45961 tatgcacttt ttccatgaac gcttattagg aaaaaacgac tttgctccgc ggctctttgc
    46021 aaatgtggat gaaatgaacc aacagttgat cactagctgg aatgcagtaa taaaagaaac
    46081 cgaccatgtt tatcatctag gcgaccttgc tatgcatccg caatatgaaa aagcaaatgc
    46141 agaaattttg gaactggtca ctcaactgca aggaacaatc cacttgatca aagggaacca
    46201 tgacagtcgc gcttttttcc gttatttaga aaaaaatgat cctaggctta ctgacggaag
    46261 tcccaaattt tatttttatg atgtaggtgc catcgttaaa ttcgaccatc aacaatatta
    46321 cttgactcat tatccgatgt tgctcgggcc taacgacact atccgcaatc ttcatggaca
    46381 tatccatcat tacagcgtac ctatcgagaa cgatgtcaat gtaggcgtag acgcaccgga
    46441 aagagaactc ttaaaggaaa aactaccatt tggcactccg ttatctgagc aacaaatcaa
    46501 agaaatctat gaagcaaaga ggaagtacga taggtcgtga aaaaactgcc ctatatcaag
    46561 tattaaacaa ataaagataa ttactcatat ttttcatttg agtaggctta ttgccacagg
    46621 aacattagga tcagaaatgg agttgtaaca agacttctgt cacaactcca ttccatacta
    46681 ttcgtctttt tgctcatggt gttcttttac cagttttttc tgtaattctt tatcataatt
    46741 tcgggcagct gacgttaaaa ataaaacgat tccgcataat aaaatcccga ttccggaaaa
    46801 caagaacatt ttttctaccc ctaaacgatc agctaatggt cctgcaaata ataatccaat
    46861 tggacctgcc aggttcatca aagagttgaa gttccctaag acacgaccta aaacattcga
    46921 ttcataactc tgctggatca ttgccatcag cagtgtattg aaatatggcg ttgcacaacc
    46981 tgctcctgca ttcaagataa gaaagtacaa gaacccttga ctatcgtttg gaaccaatcc
    47041 gcttgcaccg atcgtcaggc ccataatgat gtaggctata ataataggtt tcattcggtc
    47101 tttccatgtt cctataaaac tgatcagtgc accgcctaag agcattccga ctgcgtagac
    47161 tacttccact gctcccgcct gtccaacgga accaccaaag taatctagcg tcatcaatgg
    47221 atacagactg attgctggca tgaacaacag catcacaaat gcaccattga tcgttatgta
    47281 ccataaccct ttattatcca tcaattgctg cagcccaaat tttgcatctt taaaaatagt
    47341 aagcggaact tccaatattt caggagaaac ttttgggatc ttcacaaaaa tcaataagcc
    47401 gacaccaaaa actgccccca atacatctaa taaaataagg taattgacag gaacgactga
    47461 aaacaaagcc gcacctagag ctggcgcaat gatgaaattc gctgattgga ccattcctaa
    47521 ctgtccattc gtccttgtta tgtgagaaga tggaacgatt gtcggcataa tcgactggat
    47581 cgttggcatt tggaatgttt gtgcgaccga acgcataaac aaagacacaa aaactagcca
    47641 aatcgggaag gattctgaaa tcgttccgac tactgctaaa ataagcgcga aaatcgctac
    47701 aataatatcc gtgacaatca aaagagcttt tttatcccag cgatccacta gcggtcctac
    47761 aaatgggctt agtaaaacca tgggaatcat tcctagtaaa gtagcaaaac tcaaaattgt
    47821 cgccgaaccg gtttctcttg tcaaatacca gatgatcgca tattggacga ccatactagt
    47881 gattcctgac aaaaactgtc ccgataaaaa gaacaaataa tttctcttcc aattcgttaa
    47941 aacgaccgac tgttcatttt ccataaacat ccctcttttc tttttcattt tgtatagtgt
    48001 ttgcacaaca atcattatac gggattcttt tttcaaaaaa tacctttttc cctaaataac
    48061 aatcgtttca atttaaattt ctttacttag aaacaataaa tcagcaaaat attaaaaata
    48121 acaacatgtg ttaaatttaa aaataaaaaa gacaactaat ttgcgtcgtc cttacaaagt
    48181 tagtcatcta acaataggcc gtttcaaaac tagttgtctt tttatatcca cagatcattc
    48241 gactttttcg aataacccac ggctaatcat cccatccatc agaaaataaa atttatcttg
    48301 gctcattttc tgttttggat ctttgaaaat attgactgct ttcaatccat ttgctgtagt
    48361 gatcgacatt ttcaatgttt gaatatcttt tgatacagtg atttttaatt tgaatccttc
    48421 tttgctttgc ggcgtggcat ctaatggtcg gatcaattga taattgcctc cgtttgtttc
    48481 tgtaaatcca ttatcgcgca atgtatatct ttttgcatca ggatgcaaac gatagctaat
    48541 tggtgcgccc agtaccgttg ctgttgtttc aaatgccatg attttcacct cgataaaatt
    48601 agtttctctt tattataaaa gtttatcctg atttttacta ggtttttcag ttaagttccc
    48661 taaaaaatga aggcgttctc tcagacatct gttcatataa gaatgacttc actagttatt
    48721 ttttgacagc acgaactaat tgatcaagga aatactggat gtcgtcttcg gtatttccca
    48781 aaccaaagct gatacggatg gattctttta gtatcggtgt atcttctcca tacattgctt
    48841 ctaatacgtg tgaaggctcg atatttcctg ctgtacaagc tgaaccagta gaaatagcga
    48901 ccccattaag atcaagcttc atcagtagca aatcatttgc ttcgccaatt aagcgaagat
    48961 tcaacacatg agggagttta ttcgttaaat caccatttac ttgataaggg atttcgtttg
    49021 cttctaatgt atcaagaatc aattgctgga atcctttata tttgttgtta cgtgcttcac
    49081 gttcttcagg tgacagcagt tcaactgctt ttgccatacc ccagatccct gctaaatttt
    49141 ctgtacctgc acgccgcttt tcttcctgct ccccgcctaa aagcaatgca gggatattta
    49201 ctccgtctcg tttatataag aaaccgacgc cttttggccc attgatttta tgagcagaga
    49261 tacttaataa atcgattcct aattcttctg gatggatcgt ttggtttccg tacgcttgta
    49321 ccgcatctgt atggaaataa gctggatgat ccgctaaaag ttcaccgatt tctttgattg
    49381 gcatcaaatt tccgatttca ttgttcccgt acatcacaga gaccaagatc gtatcttctc
    49441 gtaacgcttt tttgacctct tcgatcgaca gattcccttt ttcatctaca ggcagatatg
    49501 taacgtcaaa cccctttgtc tctaaatatt tcatggtatt aagaacagca ggatgttcga
    49561 tagctgtagt gattagatgt ctgccttctt tttgacgcga gaacgctgtt tctaagatag
    49621 ctgtattatc cccttctgtt cccccactgt taaagatgat ctcgtgaggt tttgcttgca
    49681 gactgtctgc aatgatttgt cttgctgttt ccaatttttc atgcgcgtgg cgaccaaatc
    49741 catgtatgct tgaaggattt ccaaacgtgt cttgcatgat tgccgtcatc gcttcaatta
    49801 cttgtggatg catgggggta gttgccgcat gatccagata aatagttttc acttcattca
    49861 tcccttccaa attattgcta ggcacattct agcataaaat agcgaacaaa ccaaagaaga
    49921 gctcattttt gtctagagga cgtttcatgg gcatagaaaa aaggagctgt gacaaaagtc
    49981 ttgtcgcagc tccttgaagc tgctcacttc tgtcacaact tctttccctc ttttttttgt
    50041 ttattcgaat tctttttctt ccagacggaa taacggactc atcggtgtat tttcatggat
    50101 gcgtttgacc gcttcaccca ttaattctga acatgtaacg attgttaagt tttctggatg
    50161 acgattttct tctgtgaaaa cagaatcagt gatacaaata tctttgattg gtgcattgtc
    50221 taaaatactt ttcgcatgat cggacaataa tccatgtgac gcacaggcat atacttcttt
    50281 tgcgccgttt tcttttaata catttgctgc tcgtgcaagc gttgctcctg tgttcaagat
    50341 atcatctacc atgatacatg tctttccttg aacatcaccg atcacataac caccctcagt
    50401 tgaagcatca tctgcatgat ctacgatggc taatgtgctg ttcaaatatt ctgaaagact
    50461 acgtgcacgc tgaacaccgc tgttttttgg cgaaacaact acgatgtcat ctcccgtcag
    50521 acctaattga cggtaataat gagcaaacaa cggcatcgta aataaattat ctacaggaat
    50581 atcaaagaat ccttgtactt gaaccgtgtg cagatctaaa gtcagtactc gagttgcccc
    50641 tgcttcttcg atcaagttag cgatcaattt cgcagtgatc ggttcatgag gtttcgccgt
    50701 gcggtcttgc ctagcatacc catagtaagg caatacgaca ttgatcgttt tcgcacttgc
    50761 tcgcttcatt gcatcgatca tgatcagtag ttccatatag taatcattga caggtgcatt
    50821 cgttgattga acgatataca catgatcccc tcgaatactt tcttcgatat tgatggaaat
    50881 ctcgccatca ctaaattgct tcacgacgct tttacctaat tctgttccga acactttcgc
    50941 gattttttca gctaatggac ggttgccatt caaactaaaa atcttcaacg tgtcatcctg
    51001 atacttatta ctcatgtagt cctccccaaa acttctctat tcttcgatag tttaacatat
    51061 ttttccaaga ttttctgtta atttcagcaa attcttaagg aagtgaaact gttccgttac
    51121 tccaactggc aggaatgact ttatgataat cgccccagtt gtcgtgtact ttgtaataac
    51181 gttctcctgt ttcagtttca aaataagcgt acgctgtcac ccaatgattg ccatatgtac
    51241 tgccaagtac tttcaaaata ccaatcatca caggtttgcc ttcacgtata cgttttgtag
    51301 ctcgctgcca tgaacctaga agagttgctc gtgcacgctc atgattgcca ttcttcttta
    51361 aaaaactaga aatccctgta ctaacctgaa aaggaatcgt aggaagtcct agtggttgga
    51421 tctggctacg caatgccttc gtcaaaacca acgaatcagc cgtatttttc ttgcgaatct
    51481 catttggaag catccacccc ttacgatagt cttgataata ggcaaggaga actgctgccg
    51541 cgtaagtacc acaaagatag cctgaggggg tagcccattt cttatacctc aaaaaacgtt
    51601 cttctggcaa tcccacccag caatttgcga gttcctttcc tgaccttttt tcttcgatca
    51661 aaacgggaat atcttctttt ctgttgatcc atctagataa ctcgattggc tcttcattga
    51721 tcagcttcca ttttttacaa gaaagaccct cttgataagt atattttgct ggagaatatt
    51781 ctaccggatg tcctgattga tcgataatca cataactttg atcttcaaaa accagagcta
    51841 aaaaaagcaa tttacttttt cttgactgca gctgctgagt gctggctaat tttttaattt
    51901 ttttatctac tttgaaatat aaaggtttat ccactacttg attcagttgg gatcgcctcc
    51961 tttttttcat tataagtgaa ggattgaaaa aaacaaatca gtttgattgt tcgaattttc
    52021 aattttttat gttctatttg ttaattcctt cattttgtaa gataatgggc acacgaaaca
    52081 aaaaaggagc gatcgatgaa tgaacaaaga acgattgaaa caagatttct atgaagcagt
    52141 caatgaagaa tggcaaaaaa cagcaaaaat ccctgcagat aaaccagcta caggcggttt
    52201 ccaagattta gttgacggga tcgaccaact tttgatggga gaaacagacg atctgcttgc
    52261 ccatccagaa aaagtgtctt cagaaaaaat gaaacatttc cttgcatatt atcaactggc
    52321 aaacgattat gaccgaagaa atgagttgca tgctcaaccg cttcaaccta taatcgaaaa
    52381 agttgaatca ttgcagtctt tcgacgaatt gaataagcaa tttccagaat ggctgttgga
    52441 tacattacca ttgccattta atctggatgt agatgcagat atgaagaatg cgcaaacgaa
    52501 cgccttcttt gcttatccgc cttctttatt ccttccagat aagacgtatt atgcatcaga
    52561 ccatcccaac ggtgcacaac taataggcgt tttctttgat atggctgttc agttattaga
    52621 gcttgccggc aaagaaaaaa gtcaggcaga agcaatcacg gaacaagcag tgcaatttga
    52681 taaattgatt gctcctcatg taaaaagtgc agaagaaaac gcagattaca gcaaaatgta
    52741 taatccgcaa tcttttgata catttattaa atacacagat aaactggact tgaaaaaact
    52801 tgtcacgggt ttgattggga caactccaga taaagtgatc gtaactgatc cagtgtactt
    52861 cgatcatttg aatgacatcc tgacagaagc tcattttccg ttattcaaaa gctggatgat
    52921 cattaaaaca gtacgttctc ttagtggtta tctatcagaa gaattccgcc aagtcagcgg
    52981 aatctattct cgcgtattgt ctggaacaga cgaagcaatg cctcagaaaa aagcagcgta
    53041 ttaccttgcc tctggacaat tcgatcaagt agttggcgat tactacggaa aaaaatattt
    53101 tggcgaagct gctaaaaaag acgtagaaca aatggtgaaa aaaatgatcg ccgtttataa
    53161 aaaacgtcta gaagaaaatg actggcttgg ggatgcaaca aaagaaaaag ccgtcataaa
    53221 attaaataac ttaggtatcc aagtaggcta ccccgataag atcccagcat tattcgacca
    53281 gttcaaaaca gtacctgcag atcagggtgg tactttgctt tcaaatactc ttgttttcag
    53341 caaactcaca ttaaaagatc gtttcagcaa atggaacaaa ccagtggatc gttcagaatg
    53401 ggaaatgagt gctgacacgg tcaatgctta ttatcatcca tttcggaatg tgatcgtctt
    53461 tccggcagcg atccttcaag caccatttta cagtctagaa caatcaagct ctgctaatta
    53521 tggtggaatc ggagctgtta tcgctcatga gatttcccat gcatttgata ataacggcgc
    53581 tttatttgac gaatatggca acttgaacaa ctggtggaca gaagaagatc ttacacaatt
    53641 tcaaaacaaa gcacaagcaa tgatcgaaga attcgatggt ctgccttttg ctgacggaaa
    53701 agtaaacgga aaattaaccg tttcggaaaa tattgctgat gcaggcggtc taagctgtgc
    53761 attggaagca gcaaaaacgg aatcagatct ttctatcgag gaattctttg tcaattgggc
    53821 aacgatttgg cgtacaaaag caaaaaaaga ataccaacaa cttttactgc aaatcgatgt
    53881 ccatgcccct gctaaactcc gagcaaacgt gcaaccaaaa aaccttgacg aattctatga
    53941 aacatttggt atcacggaac aagacgctat gtatctagcg ccagaaaaaa gagtgcgaat
    54001 ctggtaagag gttgtgccag aagtggtcag cttcaagaaa taagaaggaa tttgggaaaa
    54061 tcgcttctca aatttttgtg acatttcggc ttatttttcg aagaagttac ttctggaata
    54121 ccatgtatta gaggttgtga aaaagctgct tagtttcaag tagtaagaaa aattttgtga
    54181 aaatggcttt ccacattttt gcataaattt gacttactac cgagaaactg gcttttgaac
    54241 accgtttatc gagaggttgt gaaatcagcg tcctgacctg agtattagag aaaaaaacgg
    54301 aaaaatagtt cctcatattt tgccgtttgt tgagctaata ccgagggtca gctgattgaa
    54361 caccgtttag tggagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa
    54421 tcaaaagcag caaggagaac ctcatctata aaaagataga aggaagtgag acatctattg
    54481 gtctcatttc cttctatttt tactttcctc agtcaattgt tttacatcat aaaaggagaa
    54541 attccactta tttttttcgc tgtttcatga cataaacaac tacaccgatt aacaaaattc
    54601 ctccagctaa tgctagcaac gggttattaa attctcccgt ttttgggagt ccttgagtgc
    54661 catttttttc actttctttt gctgtcctat ccggatgaga aggttttcca tttggttttc
    54721 catttggtga ttcatttcct ggattttctc tttctggttt gtcatttccc gggggcacat
    54781 cggcagtttc tcgcacagtg atcgcttttt gctgggtaac agattctgta tgagcagacc
    54841 atttttcccc atcaaatatt tccgaacgat aagtgacttc tagcgtatat tctccttttg
    54901 aaggtgctga aaaaatagcg gtatgattag aaaattgagc acttgactgt gtttcaacga
    54961 tttggatctt ttctgggaaa taacgcatat cttcaaagac aggcgttcct tgatttggtg
    55021 tgaaagttga cacaaaaact gtaaaaggct tcagttcaat gatatttcct tctgcattct
    55081 ccgccacacc atttgcttct tgtataataa tcggattatt ttgttcattt ggttttgtct
    55141 gatttggttc ttgtacgatt gcatactctg gatattccga agacggtgag gtttctccgt
    55201 caaaaatagc acctacagat aatggaagac catccactct ttccttttct gtttgacgat
    55261 tccccggttt aatctgcatc agtccatgaa catggatact tccattttca tagcgcgtaa
    55321 caggctgctg accttctttc gaacatgtat ttagagactc gatccaatct tttgatatgg
    55381 tatgtccaag agtattttct gattgtttct ctcgttcatt ccaatagtag ttcaacgagt
    55441 ggtagatttg atcttcgttt tgattcaatg ggcggatctg ctctctcatc tcaagattct
    55501 ctgttcggaa agataagata ccagaagcat ggtagtctgt gtttcctgct gaagaggtat
    55561 aaagagccac attatatgaa ccgttattaa aacttgtact gctattgacg ataatatctg
    55621 ttccgctatt ggaatcgatt cctttcgcaa gattttcgaa agacaaacta ttgatcaatt
    55681 catgagggcc cgttaaagaa gaaccgccca ttttgaatcc attaccgtta ccttctccct
    55741 caattcctgg tacccagccg tttcgataag caactgagtt tttgatgatt acttttccga
    55801 tcgaacctgt ttcattttta gcaaaaaggt cccaaccgtc atctgcatta tgatacgcga
    55861 tacaaccgtc aaatacattt ccttctccta ttgtcagttt ggccgcaaat ccatcggcat
    55921 cttcaaatcc tggatcggca ttttcaaaag atgtacagtt cttgactaag ttatgcgcgg
    55981 gccatgcttc gaaaggatca tttgagctac cgctgatttg gattcctgta tttccattcc
    56041 gataagcatg aatctcttcg atcaaattat gatttccaga aatctgtaat cctttttgca
    56101 tagctgcact atttgtaatg tcaaaccctc gtaaacccca gtagtgactg aacagtgtca
    56161 tcccatttcc agttccttta aaatcaagta caggacgctt gttttctgga tttttctctg
    56221 caatcaactg aatcgggttt tctcttgtcc cgttaacgcc ttttggaatc gtcaatcctc
    56281 tttcgaagga ataagttcca ggcgccatga cgattgtctg cccagcatat gcgtatctca
    56341 atgcttgtgt cagagataat ggattttgtc tgcttccgtt tcctgcatct gacccttctg
    56401 gtgttacata aactgtcgaa tatttaggtt tacggtagtc cactgtatga agaatctctt
    56461 ttgtttcata actagtcatc tctacgtatt cttctggcgg atagttttta tctggcgtaa
    56521 aactgaaagt aaattcgttc gttccttcca tcagttttgt ctgataatca aattcccgat
    56581 tcgcagtgat agccaagttt tttgcgttct taagcacctc tcctgttgct ttatttttaa
    56641 ttgtcaataa tccgtcagca tttgctctaa aggacatagt atgatcttgg tttcctgaat
    56701 gattactaga ggtcacagtg taaatcggat caatcaagcg agtaggtctt tcttgcccag
    56761 gaggatctgt cgcaggatct gagtaagcaa cttcgattcc ttctaccttg atcgtcatat
    56821 tccttgctgc agcaaatcct gcataaataa ccgattcatc tgaagcgtat aatttttccc
    56881 agtcatacat gatgtcagaa gccatttctt ctcctgtttc aggatcgtaa taatatgcct
    56941 ctaaaccagt attcgttttt ttcatctcta cgtccagttt agtaatcgag ttcgtggccg
    57001 gaaacagatt cccatgaccg tttccgaata tattataaga acctgtttct ttttccaaga
    57061 accctgctga agtctctaaa ggtgttgttt ccactgagac actcccagga gctggcgcag
    57121 cttgcggatc ttcagatgat attcctgtga ttgcccgtgt ccccaatcca agtcgcatcg
    57181 tatatttgct gccgctcgtg ttgaccactt cttgtctatc cgagtcccag acatattcga
    57241 tccgactgcc tagtatggca aatgaatttg aataaaatgc ctgcccaaac aaatgatttt
    57301 ttggtactgc gtctcttacc attaaagcaa atccttcttg ggcattcgta taggtccaag
    57361 attctatttc gatcgtcgcc cgcatcctaa agttgatgtc tttggggatt gcttgataat
    57421 aataggtcat tccatctgat ccgcttgact ggaattttcc gccgttattc gtggaagaga
    57481 gccgcacgcc gtcttctaat ggttcaatgg catacctact agcacttgtg ctttctccga
    57541 aaacaacccc tttccactct tcatttgctt cttcagattg cttttttgtc ttttcatttt
    57601 ctgattcttt catcatagga tcatttcctt cttccgtatc catatcttca ctagttcttg
    57661 gtatttcctc cattgttgac atcccttcaa tgttcacgtg tgcattttct tcgttcacag
    57721 actgttgttc gttagcagca acttcaacga cagaaattaa aaccggggta ctgagcataa
    57781 ggagattcat cattagcgca ctgtatttta tacgtttttt taacaagtgt attcctcccg
    57841 taacaaatta gaaagcgttt acttaaagta ttacctagtt tatttttact gtcaataaaa
    57901 aacaaaatta taataagtgt attttataaa aagaaaaaat ataacttaag ttgttgataa
    57961 taaagagatt tattaacgta aaaagaataa gtttttttaa aataacgtat aaaaaagagc
    58021 ataaaacaaa gtcgtttgtt ttatgctctt cttttattat tttgtgcttt ttattttatc
    58081 aaatcacttt gtttttttat aaaatttctg cgcctagtgt ggactcaaaa tgtctcaatg
    58141 cccattcatg tccaacggga tcgaaacttg ccacggcatc tttgaaaata tggagtttgt
    58201 atcctagatt atacgcatcg actgctgtat gcaacacaca gatatctgta catacgccgg
    58261 tcaaataaat atctgtgatc tggcgttctc gcaaacggat gtctagatct gttccactaa
    58321 aagcggaata atgccgtttg tctatccaat aaacattttc ctcttgctca tagtcttggt
    58381 ataaactttt taaagagccg tacaattccc gtccacccgt tcctatcaca ttatgcggag
    58441 gaaataagcg gttctccgga tgaaaggaat cttttggatc atgcgcatca atggcaaaaa
    58501 cgacaaaatc cttttgatca ataaacttct ttgtatgagc agtcagcttt ttttcaatta
    58561 cttgtcctgc tgtcccagta gtcagctttc catcctctgc aacaaaatca tatgtgtagt
    58621 caatcgagat caatgcgttc atcttagtcc tccttatacg agatgtttga caaattcgat
    58681 caccatttct gctgatcgtt tgcctgcgtc ttcgataaat tcgtcaaagc tttgtgtcgc
    58741 cgagtgatct gctgtgtcgc tcattgcacg tacgatcaaa aatgggatat tgaactgacg
    58801 agctgtttgt ccaacagcgg ctccttccat ttcgcaagct aatgcttcag ggaaattcgt
    58861 taagatttct ttgattttat ctggcgagtc gacaaatgta tcacctgtaa cgatcaatcc
    58921 ttcttttgcg ttcaaattcg ttgcttttgc tgctttaacc atttcactgc gcaaatatgt
    58981 gcttgcttca taatatagag gcattcctgg taattgtcct gggttgtagc caaatcctgt
    59041 tgcatctgca tcaaaataag ctactttgtc tgatataacg atgtcaccta cttgtaagcc
    59101 ttcaccgatt ccgccagctg aacctgtatt gatcaccatg ttcacgccgt attgttggat
    59161 caacagactt gtggtaatag atgctaagac ttttcctata ccggaacgta cgacgatcac
    59221 ttcgtggtta cctaatgaac ctgaaataaa taaagcgcct gcgcgttccc atgataatgg
    59281 ttcgcttagg ttctctctca aaatttttac ttcttcttcc attgcgccga taataccgat
    59341 tttcatcttt ttaattcctt ctttctatat aaatgcgatt gctaaaaaaa ccacacataa
    59401 cattaggata acaataataa gagatttcat caaaaaagag ttccatttgg tcgtcttttc
    59461 ccgttcgctg atccttgttt tcgtgattgg tttattcttt ttgctttctt tacgataaaa
    59521 gctggcaatc tttttttctt cttgctgata agctgtttct gcttttcgct gtttttttaa
    59581 tgactcgctt gcttgtgctt gttgtcgctt gcgaagttcg cttcgcgtaa taagcggtcc
    59641 tttggccata agccgatccc tctactttcc tttggtcaat agttcccagt attgaatcgc
    59701 ataaatcgtc tttgcatcac aaatcaactg atctttcatc gcttgttgcg cctcttcaag
    59761 agttagatga tacaactcca gtacttcgtc ttcatcttgt gctaaaggat tctcgacctt
    59821 ctctacccct tgtgcatgat aaatatgaag gacttcattt gcaaaacctg gtgaaagata
    59881 catcgaagta agatggctca gcgacttcgc acgatagcca gtttcttctt ctaattctct
    59941 agctgctgtc atttcgggat tttgtccttc tcctggatcg atttttccag ctggaatctc
    60001 caaaatcact ttttctaaag gttttcgaaa ttgtttgaca agaagcagac gatcttgttc
    60061 gtcaaaagca atgatcccga caccgccagg atgaaatacc agttctctct tcgaagttcc
    60121 tccatctggc aaacgaactt cgtctacagc aacatcaata atttttccgc tatagatttc
    60181 tttgcgactg attgtttttt cttcaaattg ctcattgttc agcatatctt ctcctgcttt
    60241 ctttgtaatc ataactgctt ttttttcatt tttcaatttt tctcaaaaac tccttattag
    60301 tttaccatag ataaacctta gattttctct aaatatagaa aatccttctt tagtccgata
    60361 ctctttatag tagtccgtat gctaaaataa gtatgtaatc gaataacgaa aagaattcaa
    60421 tactcaacga taaatgacat ggagggttta ttatgataaa acgaaattgg ccgtggcttc
    60481 tagcattggt cttgctattt ctctttgtcc gaaacaatag tttttctttt gttctaggac
    60541 ttttattgat aggtgtagtt ttagttttgt ggggactctt tggttcgcgc aggaaaaagg
    60601 gaaaacaaga agaaattcct gcactgactg acgaacttga aactcactat gaaaaaagcg
    60661 gtatgacagc gaatgaaatt tcattttttc gacaaacaat gaatcaaaca aaaaatgaga
    60721 tcaatcaatt gcaaatgaat atgcagcaga cagccaaact taaagcaatc gatctccgcc
    60781 atgatccagt caaagcagcg aaagctttat tcaaagaatt ggtgaaagaa ccaaaccgac
    60841 tgcatgaagc aagtcagttt ctttatacgc atctgccgaa tctagttgat ttgacaaata
    60901 agtataatga gatcaatgac catgagatca aaaacaaaca gacctatgaa aaactagaag
    60961 aaagcgcgca gatcatcgac cagctgtcag ctttaatcgc acaagattat caaaaattcg
    61021 ttgctgagga tctagatgat atcgacgtag agatatctgt tgcgaaacag agcttaaagc
    61081 gtgataataa atatgaacca gaacaaaagg attaactctt ttgttcataa aagaagactc
    61141 ggaacattca gatgatgtct ggctgtttcg agtacttttt ctaaagtaga gacattcatg
    61201 taagaatcga gaacagattc aacaaggagg aattttttat ggatcataaa ccgactgaaa
    61261 caaaagatgt tacaccagtt aacgatacac ttgaagattt attgaacaac ccgttttcaa
    61321 ctccaacaga tacgctgacc acttcacaac aagcggagat tgatcagctc caagagcaac
    61381 agacagctgc tcgtttaatt gacaaactac cggcggaacg ccaagaacaa gctaaacagc
    61441 tagcagcaaa aatcgatgct aatgatgcac agtctgtcat cagctacgga tcggctgccc
    61501 aagcaaaatt aagtgaattc tcacaatcga tgttgaatca tgtgcaagca caagatattg
    61561 gtcctgtagg agattcctta actgaactga tgtatcgtct ccaagaagcc aatcctgacg
    61621 aactgcgtgc cggagaaggg aacatcttcc agcgtgtctt cgggaaggtc aaacaatcga
    61681 tctatgaagt gacagcaaaa tatcaaaaga ttggtgcaca aattgacaag atttcagtga
    61741 aattagataa agaaaaagac ggtctgctaa aagataatct gatgttagaa cagctttacc
    61801 agaaaaacaa agactacttt gatgcactga atatttatat cgctgctgga gaattgaaaa
    61861 tggaagaact tcaaacaacg atcattccag aagcgatgaa aagagcagaa gaaactggcg
    61921 atcagatgga tgttcagatt gccaatgatt acacgcaatt cctagatcgt ctggataaac
    61981 gtacgcatga tcttcgctta gctagacaga tcacgatcca gcaagcacca caaatccgtt
    62041 tgatccaaaa cacaaatcag gccttggctg aaaagatcca agcatctatc gctacagcca
    62101 ttccgctgtg gaaaaaccaa gtcgtgatcg cattgacctt gcttcgtcaa aaagatgcag
    62161 taactgctca acgccaagtc tctgaaacaa caaacgactt attgaagaaa aattcagaaa
    62221 tgctgaaaat ctcagccatc gaaacagcga aagaaaatga acgtggaatc gtggatatcg
    62281 agacccttca aaccactcaa aatgatttga tcgaaacaat ccaagagaca ttgcgtatcc
    62341 aaaaagaagg aaaagaaaaa cgtcgtcatg cagaagtaga gcttggacac atggaagaag
    62401 atctgaaaca aaaactgttg gatttaaccc aatagatcac ctttcgcttg ttactaaaac
    62461 aaacgcccaa caacagttta ttacaactgt tgatgggcgt ttttcttatc tttcttctaa
    62521 cttctccatt ggagtctatt tctcattcat cttgctgtgt ccatagccat agccaaaata
    62581 aatgatcagt ccaataacca ttacgatacc gaacacgatc catgtcacag tttgcagacg
    62641 aagcatcaat acaatacaag tcaagatgga gacgattggc aatagcggaa cgaatggcac
    62701 tttgaattct ccagcttttg gtttgccaaa catttttctc aacttcagta agcctagact
    62761 aacaagcatc aaataggcga gcgccatgat attcgttagt tccgctaata cattcaatgg
    62821 gaaaaatccg gcaaagaata cagctgccac accagcggca taagtcgctt ttttcggtgt
    62881 acgatgcttt tgatcgattt ctgtcataaa cttaggaagt aagccatcct tgctgacagc
    62941 aaacagtaaa cgagcaagtg aatacatcat cgagatcgtt accgtcagta gcgttaaaat
    63001 tgcccctaca gcgatcaccg cgcccactgt tccatgtcct acatacctca ttgcaaaagc
    63061 cactgggtca ttgactccta gttcagtata cggaacgatt cctgtcaaga tcagcgtcac
    63121 gatgatgtaa aggacagtag caatcagtat cgaaccaatg attcctcttg gcacatcttt
    63181 ttgcgggttt ttgacttcct cggctgccat tgcaacggca tcaaatccca agaaagcaaa
    63241 aaacacaaga gctgcaccat ctagcacacc ggaaaaacca aaaggcatga atggctgcca
    63301 gttatcaggt ttaacgaaaa atattcctac aatgataaac aacgcgatga taccaaattt
    63361 gacatatacc atggcattat tcaaacgtaa tgctttcttg gcttcaagcg acacgatgta
    63421 agtgacgaat atcactacga gcaccgcaat caagtcaatg tatgtaccat tttccggatt
    63481 gtacccgcca gttaatgctt gtggaagttc ggcccctaaa cttttcaaaa aaccttgcat
    63541 atagccagac catccggaag caacagagga aaccgctagt aaaaattccc cgatcaacaa
    63601 ccaccctgtc agccaggcag caaattcacc aaatacaaca tacagatagg catatggccc
    63661 accaatcact ggcactcgcg aagcaaattc tgcgaaactt agtccagaca aaatgacaac
    63721 gattgcagct aagacaaatg aaagtgacag tgctggacca gcattttgat tggccgcaac
    63781 ccctgtcacc acaaatattc ccgtaccgat gatcgcacca attccaagca tgatcaaatc
    63841 agacgttttt agttcttttt tcatctcact cgtatgattg agattgatct ctttcttacg
    63901 aaacaaatcc attgaagttc ctccccattt taggttggaa aacagcgatt aaactgtttt
    63961 catataccct aaaaggatac cacctaaaat gactaaaagg caaccaacaa taacataaat
    64021 gagctctttt ttcgtttttc tttcgccaag gatgaaaatc ccacctaaag tagagataat
    64081 gatccccatt tgtgaaagtg agaagccaac agctaaacca agtgatttga ctgttagaag
    64141 catgcagatg tttcctaagc cccataataa tccacagatc atgtttttcc acacaaactg
    64201 atcgacttta actttacgga aagcaaagaa gcttgcgcct aagatcattc cgatactttg
    64261 aggtaagata attgacatcg catccaaatt cgcccagttg acgatgatgg tatatacacc
    64321 ataaccaatc gtagagaaga tcaatgctct aaaaccctta ccaaaatcaa gcattttatt
    64381 atctgtatct atttttcctt cgtcatcttg tcgggcagtc aaatacgcac cgcttacaag
    64441 aagagctaaa gcaataatac cgtatacata atctttcgtt tgtgtccatt catggaagaa
    64501 aacggctccc gcaatcgtat tcaaaattaa ttgaaaacca gtagacaatg gtagccctac
    64561 agaaacaccc atgtacttca ttccatggaa ctgtccattt tgtccaacac tccaagctaa
    64621 gccggataaa aatccgatca agaaaatcca aggggtgatt acaggactaa caacgaaaaa
    64681 gacaactaaa gaaaacagaa atgcaccgat cgtcattcct agtgtttgtt gattggcatc
    64741 gccaccaatt ttaccactta ctaaaccaat actaccccat gccaacatag ggactaatgc
    64801 tattaaaatt tccataacca atctcctttt atttcacatg ataagaaact tatcagcgaa
    64861 aacgttaaca acacaagcac tttttttcgt ttctaacgat tttctaacgt ttttcattat
    64921 aaaaatttaa gattgggaaa aataaagtca ttgttgtccc ttttccttca gttgattcag
    64981 ccgtcaaatg gatacctaat ttttcggcca gattttttgc taaataaagt cctaatcctg
    65041 ttgaatgtgt tttgctaagt cgaccatttc tcccagtaaa tcccttatca aagatccgtt
    65101 tcaagtcttc cgctgggata ccgatccctg aatctttaac tgaaaggctg actccttgcg
    65161 cttccttttc tatgctcaca atgatgtttc cgtgatccgg cgtatatttg atggcattac
    65221 taagcaattg gttgaagata aaagcgatcc atttagcatc ggtcaaaaca gtatgatcct
    65281 caccaacgat ctcgtagcga atattttttg ggataaaata atttgcctga ctgcgtatca
    65341 caggctgaat gattcctttt agtccatatt cttggatgag gtagtcccgc gagaaactgt
    65401 cgagtcttgc ataatacaaa acttgttcta cgtattcatc gatttttgat aattcatttt
    65461 ctagtaatgt atacttttga tcgtcaatat cgaactcgat cgaacgaact agcaatttag
    65521 aagcggaaag tggcactttg atttcatgga cccatgagtc aatataatct ttttggtctt
    65581 gttgattact gattgctgat tgcattactt cttggtgttc acggatcagc tgattgatat
    65641 attcttctac cagtttttct tcttctgtcc tcccaccact caaataattt tgcaaagggg
    65701 aagttttttg tatgtcggct aattttcccc accatcttct cttgctcaag taaccaccca
    65761 gcagataaaa aatcagaaag acgccctcaa tcaaagctaa ataagcaatt gtgctcaaat
    65821 caactttgat gtttggcgcc agccacatca caaagatcgt caatgcaata aaaaacagcc
    65881 atcccaagat caatgtccac tgatctttca aatatttaaa aaaattcatc ttaaccgctc
    65941 atcctttcag ggaacgatat atccctgtcc tacttttgtt tcgatatatc cttggatacc
    66001 tgcctgttcg atttttcggc gtaaccgatt gatgttgact gtcaatgtat tgtcatctac
    66061 aaatcgttcg tcatcccaca gtgctcgcag caatttttcc cgacttaaga tctttccatt
    66121 gtgcttcatc aaaataaata atagacgata ttcatttttg ctcaaatcaa tgatctctcc
    66181 gttgatttcc atacttccgt tgtcaacatt caacgtaatg ccattgtggc tcatcatttc
    66241 actagataat tctgtgtagt tgtaagaacg gcgaagtaat gcattgattt ttgcaatcag
    66301 tacatcgatt tggaaatgtt ttgtcacaaa atcatctgcc cccatgttca tagccatgat
    66361 catatccata ttcgtattcc tgctggagat aaaaatgatc ggtactttcg atacttcacg
    66421 tattttttga caccaataat agccatccaa aacgggaaga ttaatatcta gtaatacaag
    66481 ctgtggttct tctctttcaa agtctgagaa cacttgattg aaatcggtcg ttccaaaggt
    66541 ttcaaattgc catttctcaa gttcctccat gatcaattgt cgaatgatct cttcgtcttc
    66601 gactaccatg atttttgcca taaaaaatcc ctccatcttt cttcttgcta ctacaatatc
    66661 aaagaagccc ttgtgaaaca agttggctta cctggaaaat gtcattttag caaacgttaa
    66721 aaaaaactgg aaatatgcga tttaatcgcg tttgtctctt ccaagcagct taaatttatt
    66781 atgttattct taataattgg tctattatct gttatttttc tttcgttgtt tttgtctttt
    66841 aaattttcga taacaccaat aaccgaaaag cgttagcact agcaatatac ctagaaggag
    66901 tataagtaat cgataaagat ggtatttttt tgtctgttct atctttgaag agacttcttc
    66961 tgtaaaggga actcgtcttc ctgtcactag taatcggtga gtgttcacgg tgtaaggtgt
    67021 acaagtgata agtgtgacta gatcctgctt ttctctaatt gctaatgtat ttgtttttgt
    67081 tggaaggaca acaattttct caacgacttc ataagcgagc atccgaccat acacttcaag
    67141 atagaatcgg tcatcttgct ccatttcttc aagatccgta aagagttttt tctcagcaat
    67201 accgctatgg gcggtaatca cggaatgtgt actctctcct ccagttggaa aagaggtgcc
    67261 ttgcaggact gtcgctcctc tatctaacaa aagatcattc gtttcatcaa ataaaggcaa
    67321 gctaacattg attttcggaa tatagatggc tccgatcata tgttgttcgt aatattcttt
    67381 tcctggattt tggacatttc taaccgcttg ctcaaaagga tctttgactt gtcccattcc
    67441 tgggattact gatgtatgag caagcgtctg atttttcttt tcatgcactg ctaattgttg
    67501 ctcatgtttt tcttctttat cgcgttcaag ctgcttttga taattctcga tccttctttg
    67561 atccaaataa ttgctgagag catctgctaa aaatggatat gtaaaaactg cagctccggc
    67621 aagaaacatc actgccataa ataattgtaa taaaagactg atttgggttt gaggtctatt
    67681 acctattttc tttttcattt tcttcacctt cttatttaaa aaaactgcag caacctttat
    67741 aaaaccgatt gctgcagctt atttttgttg cttatacttc agacttcatt ttagatttac
    67801 ggtaccagct gtacgctcca atcatcaaac ttattccgat tagtaagaat gccaagagcc
    67861 cgttcccacc agtagcagga agtgacccgc gtttcatatt cggtactctt tctggccctg
    67921 gattttctac tcctacgatc tgaatttctt cattatagct tccataagag atgataaatt
    67981 cagtaaaggc tgcctcacct gttggaagta cataaccttc tggcgccatg gtctctttca
    68041 tttgataggt tccataatct aacccttgaa cctcaaagta tccatttcca tctgcgacaa
    68101 attctgttgc ttgtccgctt gttgcccact caattctatc tgctcctgat tcataaacag
    68161 ctaaaggcga ctccccttta taaaatattg cgtattcaga acggtcttca ttccacaatt
    68221 cgaatcttgc atctttaagc aattcactgc ttgatgcatc atatttttca aactttcttc
    68281 cacctgttgt gactttctct ggcggctcta ctccttcttc ataatcaaat tcatcatttc
    68341 gtccgatttc aataaccgct gtgttgttat ggaaatcatc cgcttctagt tctgtggaaa
    68401 ccttcaaatt atacgtgatc gttaaatctc ctccacgtgc atctgctaat ctacctaaag
    68461 tatctacttt ggctactcca ttttcttctg tcaaaatcgt cacgacaaac ccgttgctta
    68521 ctacttctac tatataatct tgtccttttg ttaaaatcgt ctcgccggct cgcacttcta
    68581 tttcctgatc ataataagtt agaccaactg taggcgtatc tgtgattttg taatttttga
    68641 taacagcgct tccgttttca aggacagaat cgatgaaata aggaataggt gctgtgatcg
    68701 tgtaagaagc cgtttttcct ctttctagat caatataaga aatcgtttct tgttctccag
    68761 cttcattaat aatcgttact tgtctaaggt cgctttcctc tacattcatc tgtttatctg
    68821 cttctctgat ttcgtttttc ggatacaaat gcacatctgt attgtatgtg tctttccatg
    68881 tagaaccatc ccacacgcca tccaccatat caggcatcat cactggcatc ataacaacca
    68941 ttggagacgc gattctggaa atatgagctg gcgaataagt ttctaagaaa agatagactt
    69001 tatctctaga agaaggtgct tcttccgtca cttggacggt agagaatacc gcttctccag
    69061 cttcattcgt tgtttgtttg tcaatacttg tcagtcgata ttttaaaaac caactttctg
    69121 tgtgccgttt ttgaatccat tcaatcgctt cggcagaatt aagaccgtct tctcgttccg
    69181 gtgttaaagg attatctcga atcaaatcgt aatatacttc cgttacgtca aacaaatcaa
    69241 aatcgactcc tggaatattt tcttcaccaa aatccgtaga aaccaatccg ctattcggtc
    69301 gttcttccgg aacagatgag aaaccttttt tgtgtaatgt aatcgtcact tcacttggtt
    69361 tttgtgcgac ttcttcggct ttgactagtt ttccgttccc gaaaatccct attcccgcag
    69421 taacgagtaa cagtacactc attcccgtga caatcatttt tttattcatt tttttctccc
    69481 cgttcttttt ttattaataa aacagcacct aacaataaaa gaattcctag taaagaaatc
    69541 aacgttcttg cttcattcgt ttgcgggaat acggaccatt ttcctgattg acctggattg
    69601 cttggaccac tcggctcttt cggtttgtcc gttgtttctt ttacggtctc gttataaaca
    69661 cgtggtgttg cggattcata ggcagagact ggaactttcc cggattctaa ttcagccatc
    69721 tcctgtccgt taactactac atattgtggt tggccttttg catccaccca aaattcaggg
    69781 atgatgacct cgattctctt acttgcttca tccatctcgt aaccttccac accttttaat
    69841 tcttcaaaat aataggtgcc agaaggcaag aaacgttgtc ctgtcgtaac aaggccctct
    69901 ttatccgaaa tgaatttgct tacatttttg tcattcaaag gatcattgtc tgctggtttg
    69961 atccattgat ttttcaagtc attagcagga gccatatcta aataatattt ccccccttct
    70021 atcatctgat atagagcaaa aacagcacct tctaatggtt ttcctttttc agttgttcct
    70081 ctttgacgtc catacttgaa gaagtatgga tctcttagat aaccgacatt tttaggatag
    70141 atatgaatct cttgcagttc ctcggttgat tctgtcgggt gataaattgg caaaatagca
    70201 gcaattggga tagctgtctg atcgatatca acatccaatc caacttctgg atcaatcgat
    70261 tcttcgaaaa tcaaataaac tgcatcccga tcttggtttt tcttaggtgc tttgatacgt
    70321 gcaatcccgt ctcctaatcc gccaaccgta tctttcccag ttgttaccga agtccctatt
    70381 tggacaagcc tttcttctgt gattagctga cggatattgt ttctgttcgt ttcagcgatt
    70441 tgctggacga attctttagg agtcatgttt tcagcagctt ttttttcatg ataataatcg
    70501 gtcatgtcgt aaatggcaaa tgtcgctcca tttagtggca ccgtctgtga aatgatatct
    70561 gctgtttccc ctgcttcctc agagatagcc aagccatcat tttcatggta ttcaaattga
    70621 tcgttataat cgatatctcg aatcatccgt ttatgcaaca cgaattccac gacatcttcc
    70681 cctgattctt ctgccgacat cgcatgtgga agaaggactg ctgcaagcgg tagtaaaaca
    70741 agtaattgaa gcatcaaaca caacagcttt ttcattacct tgctccctcc tttttagatt
    70801 gtctgacaaa caaaccatag gctgctcctg caagcgccat gaagaatgca gcaagcagga
    70861 tatagaataa tcgtccggat cctcctgtag caggcaacgg attttcagga tcgttcccga
    70921 cactaagctg taatctgatt cgatttgtct ccaaaagttc atattctaac tcttgctgta
    70981 gatcaggcgt ctctgcttct tcgtttggat aatacgaaat ctcaactttt agtgtacccg
    71041 cttcttttcc tggaactacc cgatcatttt ctatgtcagg ttcttctcga taactaattt
    71101 ctaaaataaa gtaacctgga agttttctat agctgtcagg tgacttcact tccttgatcc
    71161 gatagacccc ttccaacaag tctgaagcat tgaataggga agaatcgttt ggatctggtg
    71221 ccaagcctcc ctcgatgatt tcatactctc ctgcactatt ttgtttctca attgaaaatt
    71281 ctgcgccttc aagacgtcgg ctattcatac tgtcaatttt caaaagttcc aaatcgattg
    71341 gcgctagttc atcttctaag gttacttgta gtacaccatc gatgatttca tagccttccg
    71401 gcaagggagc agtttcgtct tcgatgaccg tatcttcaat gataaactta ccttcttcat
    71461 tcagtgcaaa ctggaacact tgatcagata gccgataccc atttggtgcg acagattccg
    71521 agacctcata ttcaccaata gacagatgca gaggttggtc gtaatttaaa tcgacatact
    71581 tttctactcc tacggcacga gaatagaagt atccgatccc aggcaaacgt ttcgattctt
    71641 ctggttctaa cggattacca gtgtatgctc gatacagcgg gaaggaagaa tcccccactt
    71701 tcctgatatc gaaacctgca ccatctaatg tatggccttc atggtctaat tttctaactc
    71761 ggatctcccg ataatcaaac gtattgtaag cagtgaatgc tacccataaa cgatcctctt
    71821 catctgttgt atacgtgaga tattgccaat tttcttcacc tgtttgcttg agttggatag
    71881 tccctatagc attatcgtaa agtcgcaaga tccatgtgtc attttcatca ggttctttga
    71941 aaccttctgg gttctggctc tcaatgattt tgtattctgc atagttggta gtttcttcac
    72001 tatccttata aacaaatgaa tctggctctc cgattggatg aataactttc tcaccatcca
    72061 cgattacata tttcccgtct tcatctactg aatagaacgt gagtctccct ttctcttcct
    72121 ctacttcgtt cacaccagaa agccctttcg ctactggata tccgatttcc agtccgttac
    72181 catctgtttc ataaagttca aactctgcgc cattgattgg catattactg ccttcaatta
    72241 gtttattgat attcatgtgg attggcttga attcatttcg catttccagt ttgacataca
    72301 actcatcata ctctgtgcct tctatgttag gctcttgtac aacagaaagc ttgtgatatt
    72361 ctccttcata ataggaattc ggatctttac cttccggtcc gccgactctc gaaccagatg
    72421 tatattcatc tacaagctcg tagtgaccta acatctcatc ttcgttggct gcatattttt
    72481 tgatttggaa ttgatacgtc tcatctacta actgataacg tggtggtcca gcgatctctc
    72541 tgatccaaaa tatgtcgctg actgctccag tttcatctcc taaaatcggc atcttcgttt
    72601 caaagatcgc tattccgtcc gtggtagttt tacttgtttc gattggttcg gcttccccac
    72661 tctctggatt ttggtcatat aatgcaaatt cgactccagc caacggctcg ccattttgac
    72721 ccttcttgct gacttggaaa ttacggcctt tatgttcgta acgaatggaa gaagatggga
    72781 aatacatccg tccagtagtg atatcattct cataatcctc caggttctga atataggcca
    72841 tattgttcac tgtgcaaaaa tttccgtctt gagctcccgc atcaagtttt acttggtact
    72901 tgatcctgac catttcccct tcacctaaag aaatcggaga aaatttataa gcttggtttt
    72961 cccgtccgac atacgttgtc ggagtcgcca ctacttctgg tggggcttgt ccatgacgtt
    73021 cttcatccca tatttctggc tcttggtact tcatgccgtt ttctcctgga tctagatggt
    73081 aaaactgaat atctgccgat ctgccagctc caaatggtga gacattaaaa ccagtttcat
    73141 cataaagtgt ggcttgctgg atcgttctct tgaaggtaga agagatatcc tccaaggctg
    73201 taacaatgtc attcttgttg ttcgcattgt aatatcgcgg tgttacgcca tcttcttcta
    73261 aatcagcaat atttttcaat acatttcgtc caatagcatc tagtcgttgt ctcccgctaa
    73321 cgtttccatc gattcctaaa ccaatggaga agatacttgg cgggttctct tgatacttgt
    73381 ttttcagcca atgatgataa gcaactgtgt tgatcgcaga tgacttttct tgcgaagtag
    73441 gactgccatt cgtattgtta ttagaagaac catcaccaac ccagtgagtc gctttattat
    73501 ctccttcttt tacctctcca taacgatagt gtacatttac ttcatcttct ggacggttaa
    73561 agtcagatgc ataggtaact ggatgagtaa accctgcatt agaagtattc ccagaaaact
    73621 cctcaaaatt tctgaacaaa acgtcattat cttcagcaat cttatcttcc atcacagtcc
    73681 agttgctcca agctccatta gtgctcgtac gataacttga ctgaatcggt gcataactga
    73741 aggtcggtgt cccatctccc acaacgatta ggattttttc tggatttcta ttttctccgc
    73801 cattgtcttt atacaatgtt tcatagccat ttttaagccc tagtgtaagc ggagttcctc
    73861 cgattggtgt acgatttaat gctgtattct cacttcccgt caaacgattg atatcatttg
    73921 tcaatggaaa gatgtccgaa ctgatttgct catggttatt gatagctgta ctattatggt
    73981 aaaaattcac cataccgatt cgaatatcca gactcgggtc agagagcaga tctttactca
    74041 tttcgtttac tgcctcaatc aacgcagcat ttttagtttg actattggtc ccagcggtta
    74101 attcactcat actcgctgac ttatctagaa caaaaacgat atcgattgga ctgatttcct
    74161 ttttctcgcc cccgatgaca tctagataga cattgtaaag ggttgttgca tcttcaggat
    74221 gtagatcaga tgctgtgctg cttggcagaa caggttctac ccattttttg atgtacgccc
    74281 cgttataatc caagtaactg ttttcaaaat tccgttcatt tccccaaagc tgaacggttt
    74341 gagctggaac gtttctatct tcttcgcctg cagttgatcc attattagta gcatagtcgt
    74401 aatttcgcca gttcgctccc ccgtttgtat aatcactatc atcgatcaag ttctctccgt
    74461 catatggcga gcctttgtct ccttgatagc gttcattgct ttgtgtccaa tttcctaaca
    74521 cttttgtata gtcattcgtt gtaaacttca tctattcttt catcaaccac cacttgaaga
    74581 ggtagttacc cttcgttcac atcggggatc ttttctgttt caaaaatcaa tgtgccggtt
    74641 tctgcttctt ttgaataaac ttttccgaca taccattctt gaccatcgat cgtctcgact
    74701 tttaggtctt ctccatcttc atcataggag gatagacctg ttccacgaac gttttttacg
    74761 gtaccaatcc cggcggctgc cgcatcgatt gctaaacgta ttctaccttc attggcactt
    74821 tccttttttt caaaagccag atgccattca agggtttctt ctttttcaat atacttccct
    74881 tcaatttttg catagtcctc atctaagaat acctcatcct cctttgtttc tgttgactca
    74941 gcagctacat ccagggtcgt catatgatag actgactgga aatatggtcc aaatagcaaa
    75001 ctgacagtta ctaactgcaa aagcttcaat tttaaccctt tcacatcctt atactccttt
    75061 caaaaatatt tgtcttcttt cacaacaatc aacaaaacaa tgcccatcta attataattt
    75121 aatttaattt taattttaaa tcaaatgata tcctttttag ttaaaaacac caattataca
    75181 acatttatta ttaaaattaa attataaaat tttataacgt tctcatttaa caaaacttaa
    75241 gttattaaga caaatgaata aacaactacg ctttcctcga aacaaaaaaa taaagcacaa
    75301 atgcgcattt acgcactcat gctttattcg tacaattaat tcagataacg gcagcgcata
    75361 ggatgccaat aacacttcct aaaatagctc ctcctaaaat gtcagtagga taatgtaaaa
    75421 gtaaaaaaat cctcgaataa gcgatcaaac aagcaaataa aaaggctaat attcctgcaa
    75481 ctggacttaa ttcgaacaac gcagctactg ataaaaaggc tagcgctgta tgtcctgaag
    75541 gaaaagaaga agtcttcggt ttacttgtgt aaaggacaag ccgacgattt ttttcataag
    75601 gtcttttccg tcttgtcgtt tttttgataa aaagcaaacc aacaaaaaaa tagatcaaac
    75661 tgccgataag aatggctaga ccatattctc tagtatcagg tatcaagact aaaacagcag
    75721 caaggagcaa ccaaataaaa ccaccattag agatattact gataaatttc aaaaaattga
    75781 tttttcgact atccgttttc cgttgcttgg cgaacttgtt gataatacta tcatcgattt
    75841 tagcaatcaa acgcaacatg ttattcctcc tttttaagaa ccttttcttg cgtacgatgg
    75901 ataaaaagca ggacttgaaa ataaaacaag aaactgaaac ctaataaagc aaaatagatt
    75961 ggtcctgcaa accagaatgc gacaagaagg atcaacgtgc ctgccaaata gaaaagcgcg
    76021 cttttgaaat cattaaaaaa caagaaaaat gcagtaatcc aagaagcttc tttttgttcc
    76081 agttgaagca agattttgta actaaagaga agcgcgctta atagaagcaa aaacaacgta
    76141 gtatacatca atgtatagcc aattccccca ccccaatagc ggaaaatctg ataatcgatc
    76201 aatagaagaa gaaaataaac acttgctaaa ctatcttgct ttccataaag agagaagttc
    76261 tcacgaaact ttttccagaa tagtgaaccg agctttttct cttcattttt tttgtaatga
    76321 taaatcatat acagaactgt tcgacttgca gttcctaatg tgaaaacagg caagacgcac
    76381 aggaaccata gtagctgtaa atggataaga cgtggaatcc attcaatgat ttctaagaaa
    76441 taatcattgg cttttttacc aatcgatcga ttcatcatcc ttttgaacct cctgtcaaat
    76501 ccatcccttc aatgaaataa cgttgtgcaa aaaagaacag caaaatcgtc gggatcaaga
    76561 caagtgttgc tcctgccatc agataattcc attgtgtcgt tgcttggttc tgaaaaactt
    76621 gcaagccaat ctgtaacgtg tatttttctt gatcttggat atataacaga ggacctaaga
    76681 aatcattcca agctgcgttg aaggaattga tcgcaatggt aatcaaggca ggtttcgtca
    76741 atggaagcat caaatgactc caaatataca aatgattcgc tccgtcgatt tcagcagctt
    76801 cgatcaattc attattgatc gataagtaaa attgacgcat cagaaatata ttgaacgcat
    76861 tgccgaagaa cgatggaacg atcaggggca aataagtacc tacccagccg atcttggaga
    76921 ataatacata ttgagggatc atcgttacaa accccgggat catcatcgta gaaagaacca
    76981 aagcaaacat cagctttttc ccaggaaaat caagcttcgc aaatccataa gcaataaaag
    77041 aatttgaaag gacattaccg atcactacta gcacagtgat gaataatgta tttcttgcat
    77101 agcgccaaaa aggaaaggcg gcaatcgtat ccagatagtt ttcccatacg attttttctg
    77161 ggaaaaaggt cggaggataa cgaacgattt cttccattgg tttcaatgaa gtaaacacca
    77221 tccaaagcaa tggaatgatc aaaatgattc ctattactgt catgaggaca taacttagta
    77281 ttttttttgt ttgccgattc acactggtct ttttgaaata atccatcatt tgccgtcacc
    77341 tccagaataa tagacccact taggtgcaag cttcaaattg acaaacgtca gaaccaacac
    77401 gatcagaaac aggatcattg acatagccat cgcataaccc atatcaaaag ctacgaacgc
    77461 cttgttccac atatgcagat tataaaaaag caaagaattt gcaggtccgc ctgttccatt
    77521 tttcgtcatg acataagctt cttgaaaaat ttggaaagaa ccgatcgtag aggtgatcac
    77581 atcgtaaaaa ataataggag tgattaatgg caaagtaata cttttgaact ttccccaaac
    77641 gcctgctcca tcgatttctg ctgattcata taaagatcta ggaacatttt gtaatgtagc
    77701 taagtaaagt agcattgctc ctccagaact ccatattttc atcaaaatca acgcaggttt
    77761 cgtccattgt ggatcaaaca gccaagctgg tccagggata tggaaccagc ccagaaatgt
    77821 gttgatcaat cctgcagatg gagaaagcag ctgcatccat aagatgtaga ctgctactcc
    77881 tgataagact gccggtaaat agaaagctgt acggaataca ctgattcctt tgattttttg
    77941 attgagtact gtggctaaaa acacactgaa aatcgtcgtc agcggtacat tgaagatgac
    78001 gaaataaacg gtgttgtata acgatttcca aaataaatca tcgtgaacga acattctttt
    78061 gaaatttgct agaccaatga aattcatctt ggatgtcaaa ttataatcgg tgaaactacc
    78121 aataactgaa aaaagcatag gccctagcat aaataccaag aacccgataa taaaaggcga
    78181 gataaataaa taggcccatc ttgcttcttt tttctttcgg atagataaac gcttcaaatt
    78241 ttcttgcctc ctctgtacct agacagtcaa aaatggatta ttgattttgc ttgactaagt
    78301 tttctactgc tttttgtgca tctgccaatc cttcttttgg tgattttgtt cctaaaagaa
    78361 tctggtcaat ctgttcattc actaatgtcg tgtaatccgg agcatctaaa ggaactggtg
    78421 tgatcaccgt atttttaaag ttttcgtccg ccatttgata gatcattttt cctttatccg
    78481 ttaggttgtc attattcact aaattctcat tggctgtctt gctcgccatg atatcaaaac
    78541 ttttttcgcc gaatttttct tgtacttctg gagaagaaag atatttgatg aattcataag
    78601 aggcctcagg atcttttgct ccgtatggta cttccaagac gaatccgcca ccccacgacc
    78661 aatggcctga accttcttct ttttctggga gctgcatcac gccaaaatca aaatcatccg
    78721 gtgcattttc catcaaacta gagtaataat tgatattttg ggcacgcatg gctactaatc
    78781 cggaaataaa tggatcagat acaccagacc caaattcggc ttctaattta ttgatcgtat
    78841 ttttcccata ataatcttgc cagtcttgga tccactccaa ggcttccact ttatttttag
    78901 tatcaatctt gactttttca tctttgtcaa accaactagt cccgttatct gcgtttagcg
    78961 cccatacatc agcccctaaa ttccataatg gataaaaacc gatgcgtgta aattcttttc
    79021 cttctttttt atctagttta cgtgctgttt cttctaattc atcccaagtt gtcggtagat
    79081 cttgttcact gattccagct tctttaaata actttttatt ataaaaaatg acttgtgtat
    79141 ctgtattgaa tgggatcgca taaggatcac cttcatattc tactgtatcc caaagctgcg
    79201 gataaaaatc cttagaagtg tctttttcta catatttgga gagattagtt gcttgctgtg
    79261 cttctgctct ttgggcaacg gaatttatgt cctgtacaat aacatcgggt gcatttccag
    79321 ctgttattgc agataaagat ttagtccaga tgtcacccca tggctgatac ttataattta
    79381 catggatctc gttttgtgat tgattgaaat cctcaatgat ttcttcgata gcttcttttc
    79441 gtgcaccgga tccccaaaag gaccagaaat caatattttt tcttccatca cttgtttttt
    79501 cagaagaatt tgctgcactt gaactggcat cgcttgcatt acttgatccg catcctccta
    79561 ataaaaacaa tgctgaactt gccagcaacc ctgtaaacaa taattttttc atattttacc
    79621 tccaaatttt aatgtaaccg atgccggttt taatataacg atatcatttt gttctgaaaa
    79681 taacaattta taaggtatga ttctaaaaaa attattaatg ataccaatac tttatataat
    79741 tcgcgagcgc tttctttgaa ttttttaatc tttcgtagca gaatgagaat gtattaaaaa
    79801 tagattagga ggaattttga tgtttagaca ccagaaagaa ttgcagtttg aagcaaaacc
    79861 agatcgtccg aatccattaa tcgcgaaata tctgcaggag ctgatcggcg gccaatatgg
    79921 cgagatgagt gtagctatgc agtacctgtt ccaaggctgg agctgccgag gagaagaaaa
    79981 atataaagat atgctgatgg acattgcaac agaagaaatc ggccacgtgg aaatgttggc
    80041 gacaatggtt gctcgtttat tagagggtgc gcctgttgaa gatcaagaag cagcgatgca
    80101 aaaagatcca acaatcggtg ccattatctc tggaatgaat ccacagcacg cgatcgtagc
    80161 tggcttagga cctcgtcctg ctgacagcgt gggcaatcca tggagcggtg cctatatcat
    80221 tgcgagtggc aacttgttag cagactttag agctaattta aatgccgaat cacaaggaag
    80281 acttcaagta gcacgtattt acgaaatgat cgatgatcgt ggcgtaaaag atatgctgtc
    80341 tgttctcctt gcaagagata gctatcatca aaatctatgg gaatgtgcag tgaaagaatt
    80401 agaagaaaaa gaaggttcaa tcttagtccc aagtactttc ccgcgtgaca aagaacgaaa
    80461 agacattgct tatgacttct ataacttctc agagggagac caaagtagtg aaggttcttg
    80521 ggctagtggc aaagcactgg atggcgaagg cgaatatcaa tggttgaaag aacctaagat
    80581 cgaaggcgct gcaccaaaat tagaaccagt aacaccaaaa atgtatggga cacctccatt
    80641 caagaaataa atatctaccc gtagaaacac ccgttttttg ttccacacgc tttgtgagca
    80701 aaactgacta aagtcattaa tcataaccac ccttcaaaag ggtggttttc tctagagcta
    80761 taagctcaaa tcaccggcca gcgcctaaag acgctggctt tcatatttta tgttcaagcc
    80821 atattgcctt tgccagtttt gcccacctct taaaaggttt atgtactact ccttagccct
    80881 taaaaggatc gtcttactct cgtacactca gcttatctaa cgcactatca tgtttttctt
    80941 gttcttgaat gtactttttg atggtcgctt cattttgtcc tacttttgtc acatagtatc
    81001 cttccaccca aaagtgtcga tacccaaatt tatattttag atttgcacaa tctcttgatg
    81061 atctcctgaa tattggctcg atattgatta taaattattt ttcttctata ctttggtgtg
    81121 aatacaatgt ggtatttaca catctacttt gtacgggcta aactatttcc ctttattgct
    81181 ccacccgcat agcaagtggt tttgtatttc aatcgctcgg cgcgctcaat taggtctaaa
    81241 gacaataaat ctaaaaaccc gctgcttcac tgacagaaac aacgggtttt cagaaaaaaa
    81301 tgaaatgaaa aagatctctt acggcaatct attttatttt tttgattttt tataaatgga
    81361 aaatgcttca agaagtccaa gaaataaagc cgtataaaaa caagaaccta tgaaatcttt
    81421 atttattaga tattcaacag aaatcccgat aacactagcc aacaatatat ttatcagaag
    81481 tgtaaaataa ggatgctttt tatagaatag aactagtgtt gttttcatag actctccttt
    81541 cttcatattt ccaattaatc acaaattcac ggcattacta gaaaaattaa aggggcgcag
    81601 aagtggaaaa atactcttcg actttcccta caaaccaggc catcttgtgt ttaataacta
    81661 taccaaatct aaggtacctc taaatctaaa ttccatttgt ggcggtgacc tccaattttt
    81721 aactcttcta tctcccatcc agtatacata accttgatac ttcgaccact tatatatcga
    81781 acacacaaat acctatccat tgcaggagta ctacctaact tagttgctac ttgcatctaa
    81841 ataacagctg aaaagatagg acttactctt agtaaagtat ctgaactatt aatttttaaa
    81901 ctatcatttt tatcctcaac tacatgcaca tctgttgcaa cttcactttc tgtctcatcc
    81961 agataaatga ttaaggaatc gggaattgca atatcttcag ctgacgctgg aatagttgag
    82021 ctaaattagt catcatatct ttattataaa ataaccaaca gcaaaaaata caatgaaaaa
    82081 caaacttgga actaatgtat cattaataaa tgttgaaaaa ttcagcaact cattactgta
    82141 tgattttagc agcccaacca acatataccc tataaaagct aataagatgg ttaggaatcc
    82201 tttagaattt ttactcattc atagacactt ccttaaataa cttttattat agaaggtatt
    82261 gtaaataata atattgacaa aaagtgactc aaaataaaaa aaaacttaca ttatactgga
    82321 atgaactgta ttgatagtgt acctaaaagc tctactgaca taagatcgtg taatcggtaa
    82381 agtaatttta ttaattatac gggatgtaat caattagaga ataaactaat cataaaaggt
    82441 acttttacat tcataattgt cgctttgaga ttctactttg gttcactatc tgacccaatt
    82501 gcacattttc gatcattaca agtattggtg tcgttagaac aactaaataa aaactagcgg
    82561 tagatttttc agaatctatg ctaatttctg tatggatgtt ccagtgatgg caaatttctc
    82621 ttttcattgt ttttcttgtc gcatgatatg cctttttgtg ttattcagtt aaactataga
    82681 aattctttcc tagacagatc ttgatcccaa attttacgtt tttgagcatc gatatagttt
    82741 aaaatgacat tactcatatc taaagagttt agatttttta ggactaaaac tgtcagttgt
    82801 tctttttctt ctttctgtta aagtattgtc gcgacttttc gtatacgtta agatatgtcg
    82861 tgaaaaaaca agttttgtga cacaaaaaaa cgaatgactt gaggaaatca cctcaatcat
    82921 tcgtttaaaa tgctatatat tctttagttt aagatacgga aattaatgcc atcgaccaca
    82981 ctagtagaat gaacgacatt tacttggcct ttttttaatt tcgttatgtt tagcatataa
    83041 aaatattata gagtttactt acaatgctta aaacatatac tgtataatct gatcaatttt
    83101 agccatgtct tgcaatggta agttttctat ttttttgagt tttcgttcct taaaatcaag
    83161 agattttaat tgtgtaataa ttacttgtcc ttttatatct agctcttcag gtaatgagta
    83221 acgtgtcggt aaattcttta tagtggaagt aattggacat atgaccgaaa acattgtttt
    83281 acggttaaat tcataacgag agacgactag tcctggtcgt cttttttgaa tttcttttcc
    83341 tacggaggga tcaaaatcaa tccatacaat atcacctttt ttaggaatat aaattctttc
    83401 ttctgacact ataaaatttc tctcccttca ggagttaaat cttcccattc gtctttctca
    83461 taatactcgg cctcttcccc accactaaat ggatcttcaa tttttggaac taacgtaatt
    83521 gttccatcat cagaatacac aacgatatat tcttggtttt ctgaaggttt ctttccgtta
    83581 tcagaaggta aagttaccac tacagaactt ccttgtaatc tagattttgt aacaagcatt
    83641 atcatcactc ccttaataaa agtatactat ataacactaa gtaacgcaaa attccccttt
    83701 gtaaactatc tagaaaattg ttttgtttaa agtatatctt attggatata aatagaaata
    83761 aattgtagcc agttcatttt ttctttaact aaaaaaataa tccaagaaac attgaaccta
    83821 tggatccaaa agctacccaa atactatagc taaccccccg ctaccttcaa ttttgcagat
    83881 aaaacgcttt gggagaaaat ttcaaagaca acaggccatc ctatcatgcc cgattataaa
    83941 caaaaagctg gctattcctt ttgctctgac aaatttcaat tgggaaagtt cacgaaacta
    84001 gcaggtgaag aagtttcaac tgttcggatc aaagaatgcc cgcttcaaat agaaacattg
    84061 gttcaacgaa tttcaactag acaagacttt gctattgtag aacgtgagat cgtagctatt
    84121 tttgtagaag aagggatttt acatgatcca actcatatca atgtggataa atggcaacct
    84181 cttatctata aattcagaga atatacaact gccaaccagt cgttaacttt gaattttaga
    84241 ttccaagaat tcaaagagtc ataatgataa acatcgttag gtataaataa aaaagactcg
    84301 cagcacgagt aaaaaacaaa tagaagctat acattagaaa ggtcgactgt gaccctatag
    84361 atgcagtata tgcagcttat gagcatttct tctgttctct ttgtttttgg gatctgtgct
    84421 gaagtctttt tcgttttttg ccgctctttc tttgaaaaat cgattatgtt ataccttctc
    84481 cattactaat tcaggcatct gctgagtaat gatttttcgc gcaaaagaaa tatctgttac
    84541 ccaaggttcg atttgttctt cagtcaagac aagcggcatt cggtcatgga ttggtgcgac
    84601 tgtgcggtta ggttcagtag tcattatgat tgattctgcc attttttcat cctgatggct
    84661 acgataaaaa ccgccaatat acactatttt ttccttattt gaaaacataa atttgtcttt
    84721 ttcttcattc cactcattgg gaaaacacaa cgattttgca aaaatggttg atgaaaggtc
    84781 tttttttctt ctactgtctc tgcacgggca ttaatcatca attgtccttt tttaaatccg
    84841 gtaaatcccc acttcatgat ttccggagtg aggatgtttt cttcctcttt tcttaacgtc
    84901 acaacaagat ttgacggaaa aacttctcca gctgctaatt ctgctgcctg cttcggttgt
    84961 ttcgtctggg cttctcgata ataattctga aggagctctg actctagatc aaaaaaataa
    85021 cgaccacaca tcctaatccc tcccaatctt tttttctatc atacactgca acaagaagtt
    85081 cgcaccaaca aaacgctttc aatttttgta gaactaaaaa agttgtgaca agtgacaaac
    85141 tctccagtga atggtattct cctgccaact cctcggtcac aagtcacaat attcaacaaa
    85201 catgagaagc tgctttttga aattgttcct tgtgactcgg agtgaaacgg caggcttacg
    85261 acctctgggt aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa
    85321 aatgtagaaa gctattttca caaaattttt cttaatactc gaaactaagc gactttttca
    85381 caacctcttc cttaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccaaac
    85441 gaaaaatatg agcagctatt tttatttggc tgttcttatt acttgatgca gggcagcttt
    85501 ttcacaacct ctccactaaa cgatgttcaa tcagctaacc ttcggtatta gctcaaaaaa
    85561 cggcaaaata tgaggaacta ttttgccgtt tgtttctcta atactcaggt caaagcgctg
    85621 atttcacaac ctctaataca cggtgttcca gaagtagctt cttcgaaaaa taagccgaaa
    85681 tttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca
    85741 cttctgtcac aacctctaat tattaaagaa ccttttgcga agttaacaat ctttctttga
    85801 tcaattgaaa attctgccta agtagtgata gatcctgtgt gactttcaac aataagatac
    85861 ttccctggat ttcagcaatc aacgctttgg cttgacggtc tgcttcttca tcggacagtt
    85921 tttcttcaga aagtgccagg atattttgtt tcgtatactt gacccattga ttgactaatt
    85981 ctagtagcaa cagacggtat tcttcatcca ctgtactcaa ctcaataatc aaattaccta
    86041 caggacagcc atgataagtg atctgtgtct catgatcagc gaaaatccag tccaacattt
    86101 cttctaatgc ttcttctggc tgttttccag catttaagat gtcttcgaac aattctgtct
    86161 gccatacgtc catatgcgca tggatcaccg ctagacaaac ttcttttttt gaagaaaagt
    86221 aataataaaa ttgacctttt cctgtatcag aagctgctag aatatctcgg attgacgttt
    86281 catgatagcc ttttttataa ataagatctt tggtcgcttc caagatcttt tcctttgttt
    86341 tcaatgatat tctccttttt catttctcat agtcctatat tatacagtaa attcatcatt
    86401 ttttcttctt aatcgtttaa aaaagactgt gccaaattat ctgacacagc cctcactata
    86461 aaactgttct catatagcta gatgttcatt gattcaagaa ctgcgaggac aaaagcaatt
    86521 cctatcttat gatagttgct ctaatacttc ctctgttgtc atcacttgat ctgcaataaa
    86581 gccaaagttc gtcaacgctg catccattgc ttcttggcca ggagcaccaa ttgcatctgt
    86641 cgctaccaca acattgaatc cactctctac caattcacgc atatgggaat cgctacacaa
    86701 gtttccgttc attccaccaa gaattactgt gtcgattcca ttttttctca attggagcgc
    86761 caaatcattg ctttctggtc caaagatttt atgaggagag ctgatgatcg tattttcatc
    86821 caaataaggt ttcaattctt cgataaaatc ggctcctgaa ccttcttcca ctgattcata
    86881 ttgacttttt ctagcaaaca tctgctgctc aagcatcata tgttctcctg caccgccaaa
    86941 ttgccattta tggtcatgtg ggtaaaaata atgaggagaa ataaagagtt tgtatccttt
    87001 ttcttttgct tgttttacca tttcaatcat attttcgatc gtattgtatt tttctaagat
    87061 atcttttgtc aaaccaaagc caccgcctgc tggtttcaag aactcgactt gcgggtcagt
    87121 gagaactact gctgtatttt tattattgaa catggtggat tctccattcg ttatttattt
    87181 taatacatca tttagagctt cactcattgt cggatgagaa tagatttgat ctctcaataa
    87241 cgtataagga agttttccat tcatagctag cgaaatcaag ttgatgactt catgagaatc
    87301 ttccgcatag atacttgccc ctagaatcaa gtcagtttca gggtcgacta aaactttgaa
    87361 tacaccttta ggatcttcta atacttgtgc tttagggaca ccgcttgtca tatacttgaa
    87421 taatttgtaa ttgacgcctt gtgctttggc ttgtttttct gttaaaccta cattggataa
    87481 agtcggagtg ataaatacac tgtaaggcac agctttccgg ttattcgttg ttcgtttatt
    87541 ctcgcccttc aactgatcca taatgattcg ataatcatct agagagatat aagtgaactg
    87601 caatccgcct ttgacgtctc caatcgccca aatgttgtct gcatctgtac gaaggtattc
    87661 atccacagcg attgctccgc gatctgttag tttaacatct gtattttcta atccaagtga
    87721 tgctgtactt ggttttcttc cagttgcagc caaaactttt gacgcttgga ttgttacttc
    87781 ttggccatct tctgtaaagg tgacggcagc tgttgattct tggtctgcta cttgatctac
    87841 agatacacct agatggaatt cgattcccgc atttgtcatg tcttctaaaa tcatttgcgc
    87901 gatatcttca tcttcacgtg gaagaaattc agaatgggca tcaagaacga caactttaga
    87961 tccgtattca ttgaacattg atgcaaattc caagccaata tatccagccc cgatgatcac
    88021 taatttttcc ggtaattgtt cctgatccat cgcttgcgta gaatcaatca agtagcgact
    88081 tgtattcaat cctttgattg gtaaaatgat tggttcagaa ccagtattga tgaaaatccg
    88141 ttcgccttca acaatcactt tttcaccatt attcgtcact tcgatttgat ggttagaaag
    88201 aaaacgtgct gtaccgtcca tcactgtccc agttgcctca tcgctgatca tatgataatt
    88261 tttggcgcga agcatgcccg tcaatttttc tttccgagca acagcctctg taaagtcgat
    88321 tcctctttct ccattgaaaa tcaatgattt agaaggaata cagccgatgt tgatacatgt
    88381 tccgccatac atacgtgttg acttttcaac gactaaaacc gattcacctt ttgaagctaa
    88441 cgccttcgct aaagtcttac cgccctttcc aaaaccgatc acaatatttt gatatttttc
    88501 catcattttt ccctcgcttc ttttttacct accgattggt acaaaaatat gataaccgat
    88561 aattgtctat tctccaaatc atctgcttta tttgtcaaaa aaaaccagac aaaaagcggt
    88621 cctttcacgt ttttagtctg gttcgatttc ctttattctt ctaaacaatc gttacttcta
    88681 catcgatatt tcctctagtt gctttggagt aagggcagaa ttcatgcgca tcttctgcaa
    88741 ttttttgggc ttcttcttcg ctgatgccat cgatatgcac ttctaatact acaccgatct
    88801 gatagccgcc atcatctaaa ttataaagag agacacgtgc ttttactgtg gactctgctg
    88861 tcattcctgc ttctttgatc atatgttgta ccgccccatt gaaacaagaa gcataacctg
    88921 ctgcaaataa ttgttctgga tttgttcctt ctgcatggat tcctggagga gtgattttca
    88981 tatgcatcga gccatttggt gcctcgactt ctccattgcg cccgccatgg ttgatcattg
    89041 ctgtttcgta tgcttttttc attgtactgc tcctttcgat tgaccatttg ctacttggct
    89101 ataattatag tgtatgacaa gtaaggcgct ttctacaaaa attctgctta ttcgaatacc
    89161 agaatgccgt cttctactat ttttccaaaa aacaaaaaaa tactactcgt gaacaacagc
    89221 gtcatatttg ttccaaaata aatagcaatc ttttctacat aatcttttat atgattgatt
    89281 ttaagataca tatataccag aaagttgacc ccataaacca atactgttaa aaaaataacc
    89341 atattcgtta ccattttttc ctccttttgc tggtctccct accagcactc gatttaacca
    89401 taccactttt tttgccgtcc aagcaactag cctttcaaaa agactggttt attctgctgt
    89461 taatgattca agatcagaaa aatgtccgaa taattttgct aattttacta acgccaactt
    89521 gttctttccg aattcatcat tttctatctg taatactagt aacggctcat gtaagcttaa
    89581 acggatcaaa aaccagccgt ttccgtatgg ctcttctaga tcatatcgaa taccttcttc
    89641 attttccggg tcgaagttca tccctttttc ttcttccaac agtcgcttca tttcttctaa
    89701 tatcttgttt ccttgttcgc gtggttcatc gctgaacaat tttaatcgga tttcttgtac
    89761 ttctacgggc tgtttcaact ctttgatttg ttcatctaat gtgatacctt ttctttttaa
    89821 ttctggcaaa agcatcagga tctttgcgat gacatatgca ccatcatcca gaaaatagtt
    89881 ttccttgaat gcagcgtgtc cgcttgtttc gatggctagc tgtgtatctt tcccaagacg
    89941 gttaagttct aatgctttat tgattacatt tcgatagccg gaaatataac gaacttggat
    90001 gcctcctttt tcttcaatga atctttgtag atgagaagaa gtaggggaat tcgtcacgat
    90061 tcttgttcct ggatgctctt ttaatacgat tgtacttaat actgcgatca aattatttcg
    90121 attgatcact gttccagaag cactgacaac tgcagaacga tccacatctg tatcgaaaat
    90181 gatcccaaga tctgcttcat ttgctaaaac agcctgcttg atactttcca tcgcttcttt
    90241 attatcagga tttgggatat gattaggaaa tcggccatct ggttccaaaa attgggaacc
    90301 tgttgaatcc gcacctaagc tattcaatac tttttcagca aagaatccac cagcaccatt
    90361 tccggcatca acaatgattt tccaaccatt tagtggtttg ctttctagtg ttccaatccc
    90421 ctttttaatt tttgtgacta aatcttgcgc ataaggtgtc aaaaggtctg ctttttctac
    90481 gcttccagtt tgttcgcttt ttattttttg ctgctgtgat aggataaaag caatatcttc
    90541 tttttctgct cctccttctg aggtaaagaa ttttattcca ttataataat agggaagatg
    90601 gctagcagtc agcataaccg cagcatcgca cgagaactgt tcaaattgag tggacataaa
    90661 catagcaggc gtagtagcta attcgaaatc gatgacatgt atcccttgtt ctttcagact
    90721 ttggatcaac gcctctttca gtgctggtcc gcttatccta ctgtcatgac caatcccaat
    90781 cgtccatttt ttatttggat cggttgattt cttctttttc tttatccagt ttgctagtcc
    90841 ccagccgatc ttttttacca tgtctgtcgt caagtttact tcatatcctt caactggtaa
    90901 tgcgattcct cgaatatccg atccattttg cagcgctttc atatctttca tataaaagtc
    90961 ctcctcattt attccctcat tttttccagc ttttctgcaa atcgctgtgc ttcttcttct
    91021 gagcggcaaa taataatgaa tgtatctaca ccggccatcg ttccgacaac ttcagggtaa
    91081 gccacttcat ctagccaatt cgttaccaca tcggcaccat ttcgttcagt caatacgata
    91141 accatgaact gaacagactg gatacgcaaa acctcgcgtc taattgctgt acgcaaacgt
    91201 tcttcattta aagaaacaga tggctggtta aataatgtat agcgtactat tttgttttca
    91261 ttttgacttt ttactaactt catttctcga atgtctctag aaatcgttgc ttgagtcaca
    91321 tcggcgcctg cttcatgcag ccgcgcaagc agctcttcct gtgtcccaat aggttgttct
    91381 gtaatgatct ggcggatcag tgcttgtcgc tgtttctttt tcatattaga cacctctcaa
    91441 tgttgattat agcaaaagat aagtaatatt tcttcatatt ttggtatttt ttacttttat
    91501 tttttgtttt cattcaggtt gctaaccttt ttctatttta acacgcaaaa tcgtcttcat
    91561 tttttcaggt gctgattttc ttggatcgct gatgtaaatc tctttgtgtt ctttagaagc
    91621 tctttcatag ccttcttttg cgatgaatgc ttctaatttc tcaaacgttg ctggttcttc
    91681 ggcatagggc ccgacgtgta agatttgggc acaaagacct tcttccatct ttttgaatac
    91741 tacttgttct ttcaagtctt ccggaagttt gctagaacgc tgaatggctt cttgtgctat
    91801 cgcttctgta acaaagtcag gctgtcggat catcaattga taagaaaaat gttctttttt
    91861 catcactggt tcatgcaaat acttttcttg cagtccccat tgtccttcca gtggatagac
    91921 agtatacatc tgataatcag gaatcagcca atttttttta ggcgacatgc gtattgcata
    91981 gctgactgca tatagacagg ctactcttcg tttaaagtct tcctgattcg ggtcgccgat
    92041 ccctctgatg ctaaagaatg attttttagg aacctctagt atttgcgggc tttttttcat
    92101 actatagctc ttgtctttac gccattcaat tttttccatt tttcttcctc cgcgaaattc
    92161 catttagtta tttattatca tacctctttt tgagtgactt ggctaatcgt gttgacacta
    92221 tttttcagtt tgtgctagaa taagtgaagt aaataaatcg tacagataac acgtttcggc
    92281 gtgtcgagag agaggcggtt tctattttta taatagaaat cactctcttt tt
//
LOCUS       DAFELK010000005        83867 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFELK010000005
VERSION     DAFELK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 83867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.005"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..1348)
                     /locus_tag="LP433_000476"
     CDS             complement(<1..1348)
                     /locus_tag="LP433_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2004668.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQM"
     gene            complement(1776..2849)
                     /locus_tag="LP433_000477"
     CDS             complement(1776..2849)
                     /locus_tag="LP433_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2004669.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(2846..3673)
                     /locus_tag="LP433_000478"
     CDS             complement(2846..3673)
                     /locus_tag="LP433_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004670.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(3674..4480)
                     /locus_tag="LP433_000479"
     CDS             complement(3674..4480)
                     /locus_tag="LP433_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004671.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(4492..5577)
                     /locus_tag="LP433_000480"
     CDS             complement(4492..5577)
                     /locus_tag="LP433_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004672.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(5594..6136)
                     /locus_tag="LP433_000481"
     CDS             complement(5594..6136)
                     /locus_tag="LP433_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2004673.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            6394..7383
                     /locus_tag="LP433_000482"
     CDS             6394..7383
                     /locus_tag="LP433_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBL2004674.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            7380..8117
                     /locus_tag="LP433_000483"
     CDS             7380..8117
                     /locus_tag="LP433_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBL2004675.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            8114..8665
                     /gene="coaC"
                     /locus_tag="LP433_000484"
     CDS             8114..8665
                     /gene="coaC"
                     /locus_tag="LP433_000484"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBL2004676.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            8681..9313
                     /locus_tag="LP433_000485"
     CDS             8681..9313
                     /locus_tag="LP433_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2004677.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            9398..10045
                     /locus_tag="LP433_000486"
     CDS             9398..10045
                     /locus_tag="LP433_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2004678.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            10050..11033
                     /locus_tag="LP433_000487"
     CDS             10050..11033
                     /locus_tag="LP433_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBL2004679.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(11436..12950)
                     /locus_tag="LP433_000488"
     CDS             complement(11436..12950)
                     /locus_tag="LP433_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBL2004680.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            13088..13894
                     /locus_tag="LP433_000489"
     CDS             13088..13894
                     /locus_tag="LP433_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004681.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(14069..14638)
                     /locus_tag="LP433_000490"
     CDS             complement(14069..14638)
                     /locus_tag="LP433_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2004682.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(14721..16781)
                     /locus_tag="LP433_000491"
     CDS             complement(14721..16781)
                     /locus_tag="LP433_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBL2004683.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(17058..18536)
                     /locus_tag="LP433_000492"
     CDS             complement(17058..18536)
                     /locus_tag="LP433_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004684.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(18834..19769)
                     /gene="murB"
                     /locus_tag="LP433_000493"
     CDS             complement(18834..19769)
                     /gene="murB"
                     /locus_tag="LP433_000493"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBL2004685.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(19842..20762)
                     /locus_tag="LP433_000494"
     CDS             complement(19842..20762)
                     /locus_tag="LP433_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2004686.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            20875..21627
                     /gene="xth"
                     /locus_tag="LP433_000495"
     CDS             20875..21627
                     /gene="xth"
                     /locus_tag="LP433_000495"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBL2004687.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            22491..23024
                     /locus_tag="LP433_000496"
     CDS             22491..23024
                     /locus_tag="LP433_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBL2004688.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(23514..24038)
                     /locus_tag="LP433_000497"
     CDS             complement(23514..24038)
                     /locus_tag="LP433_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2004689.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(24031..24504)
                     /gene="tsaE"
                     /locus_tag="LP433_000498"
     CDS             complement(24031..24504)
                     /gene="tsaE"
                     /locus_tag="LP433_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBL2004690.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(24627..25607)
                     /gene="pta"
                     /locus_tag="LP433_000499"
     CDS             complement(24627..25607)
                     /gene="pta"
                     /locus_tag="LP433_000499"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBL2004691.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(25760..26440)
                     /locus_tag="LP433_000500"
     CDS             complement(25760..26440)
                     /locus_tag="LP433_000500"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL2004692.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            26566..27435
                     /locus_tag="LP433_000501"
     CDS             26566..27435
                     /locus_tag="LP433_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2004693.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            27461..27976
                     /locus_tag="LP433_000502"
     CDS             27461..27976
                     /locus_tag="LP433_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004694.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(28023..28616)
                     /locus_tag="LP433_000503"
     CDS             complement(28023..28616)
                     /locus_tag="LP433_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2004695.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(28641..28820)
                     /locus_tag="LP433_000504"
     CDS             complement(28641..28820)
                     /locus_tag="LP433_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004696.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(28897..29406)
                     /locus_tag="LP433_000505"
     CDS             complement(28897..29406)
                     /locus_tag="LP433_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004697.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(29502..29882)
                     /locus_tag="LP433_000506"
     CDS             complement(29502..29882)
                     /locus_tag="LP433_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2004698.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            30212..30961
                     /locus_tag="LP433_000507"
     CDS             30212..30961
                     /locus_tag="LP433_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBL2004699.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(31145..32422)
                     /locus_tag="LP433_000508"
     CDS             complement(31145..32422)
                     /locus_tag="LP433_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004700.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(32501..33145)
                     /gene="pcp"
                     /locus_tag="LP433_000509"
     CDS             complement(32501..33145)
                     /gene="pcp"
                     /locus_tag="LP433_000509"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL2004701.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(33344..34288)
                     /locus_tag="LP433_000510"
     CDS             complement(33344..34288)
                     /locus_tag="LP433_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL2004702.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(34290..34976)
                     /locus_tag="LP433_000511"
     CDS             complement(34290..34976)
                     /locus_tag="LP433_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL2004703.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            35449..35769
                     /locus_tag="LP433_000512"
     CDS             35449..35769
                     /locus_tag="LP433_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL2004704.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            35930..36835
                     /locus_tag="LP433_000513"
     CDS             35930..36835
                     /locus_tag="LP433_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2004705.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            36832..37605
                     /locus_tag="LP433_000514"
     CDS             36832..37605
                     /locus_tag="LP433_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2004706.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(37782..39206)
                     /locus_tag="LP433_000515"
     CDS             complement(37782..39206)
                     /locus_tag="LP433_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2004707.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            39417..39863
                     /gene="nrdI"
                     /locus_tag="LP433_000516"
     CDS             39417..39863
                     /gene="nrdI"
                     /locus_tag="LP433_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL2004708.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            complement(39933..41915)
                     /locus_tag="LP433_000517"
     CDS             complement(39933..41915)
                     /locus_tag="LP433_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2004709.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(41929..42825)
                     /gene="murQ"
                     /locus_tag="LP433_000518"
     CDS             complement(41929..42825)
                     /gene="murQ"
                     /locus_tag="LP433_000518"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL2004710.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            complement(42828..43889)
                     /locus_tag="LP433_000519"
     CDS             complement(42828..43889)
                     /locus_tag="LP433_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL2004711.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(44101..44667)
                     /locus_tag="LP433_000520"
     CDS             complement(44101..44667)
                     /locus_tag="LP433_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2004712.1"
                     /translation="MVKENFVNEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQALAEKVVDLPVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELISYE"
     gene            complement(44695..46197)
                     /gene="eat(A)"
                     /locus_tag="LP433_000521"
     CDS             complement(44695..46197)
                     /gene="eat(A)"
                     /locus_tag="LP433_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL2004713.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            complement(46455..47576)
                     /locus_tag="LP433_000522"
     CDS             complement(46455..47576)
                     /locus_tag="LP433_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL2004714.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            47702..48643
                     /locus_tag="LP433_000523"
     CDS             47702..48643
                     /locus_tag="LP433_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL2004715.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(48786..49682)
                     /locus_tag="LP433_000524"
     CDS             complement(48786..49682)
                     /locus_tag="LP433_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL2004716.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            49964..51304
                     /locus_tag="LP433_000525"
     CDS             49964..51304
                     /locus_tag="LP433_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2004717.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            51499..51942
                     /locus_tag="LP433_000526"
     CDS             51499..51942
                     /locus_tag="LP433_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBL2004718.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(52205..53623)
                     /gene="nhaC"
                     /locus_tag="LP433_000527"
     CDS             complement(52205..53623)
                     /gene="nhaC"
                     /locus_tag="LP433_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL2004719.1"
                     /translation="MEKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKKYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDILEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFMFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(54027..55250)
                     /locus_tag="LP433_000528"
     CDS             complement(54027..55250)
                     /locus_tag="LP433_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBL2004720.1"
                     /translation="MTTTLSTNQLKDLIQYRLPEYQALALAIHDHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTGFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDEIGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDAALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAALSTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSEKGLASIAIAAELLANTALDLLREPKLLEKIKQE
                     HQEIVARKKQEGATF"
     gene            complement(55282..56121)
                     /locus_tag="LP433_000529"
     CDS             complement(55282..56121)
                     /locus_tag="LP433_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL2004721.1"
                     /translation="MKKIIRFAVITFVAIIWLAGCSQGKAATTEKKETTVKLGIIGED
                     TDVWDDVKDRLKKENIHLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNEEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENKKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDEHARPYVNIIVARKEDEDNKTYQKIVDAYQTEETAKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(56138..56818)
                     /locus_tag="LP433_000530"
     CDS             complement(56138..56818)
                     /locus_tag="LP433_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004722.1"
                     /translation="MTEFFKTYLPNVYLIPDEFIEATKQTLYMSFWTAFIGGIIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILVLVFLSQFISN
                     QLIKKVTH"
     gene            complement(56820..57893)
                     /locus_tag="LP433_000531"
     CDS             complement(56820..57893)
                     /locus_tag="LP433_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2004723.1"
                     /translation="MIELRDISVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEAGK
                     IIEKGSSIQIFSHPEEELTKDFIRTATHLDQALETISAHAAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKVTILQKNELDNRIKVIEGGN"
     misc_binding    complement(57952..58190)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(58233..58466)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(58543..59214)
                     /locus_tag="LP433_000532"
     CDS             complement(58543..59214)
                     /locus_tag="LP433_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2004724.1"
                     /translation="MKGAIFDLDGLLVDTERTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KKWKQSFDILVQAAGSPEKVQEVRAKREEYFYQQLTSGAIQLKPYAKEILTDLKERHM
                     KLGIATTTVTKRATDILDHFQLADYFDTFTFGDEVSENKPSPVPYLTALERTGLEALS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYSVEEKEKLNLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(59302..61980)
                     /gene="mgtA"
                     /locus_tag="LP433_000533"
     CDS             complement(59302..61980)
                     /gene="mgtA"
                     /locus_tag="LP433_000533"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBL2004725.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASPNGLS
                     EEQIERSRETYGENAISYGKKTPFIIEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGEYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNDTLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEAAETLDTDTINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVAPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELITGEKISEMNDHELAQVAEEHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKIPFIQSNATFAMLVITTLGIIVGSVLPFTGFGAELGLM
                     PLPGNYWLWFFITVVAYLALVTAVKKIYIRRFQELL"
     gene            62640..63077
                     /gene="ndk"
                     /locus_tag="LP433_000534"
     CDS             62640..63077
                     /gene="ndk"
                     /locus_tag="LP433_000534"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBL2004726.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFATMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKGADAVPGTIR
                     GDYALPGTENIIHASDSRDAATKEIARFFPPFDTNKPSEKAAK"
     gene            complement(63099..63965)
                     /locus_tag="LP433_000535"
     CDS             complement(63099..63965)
                     /locus_tag="LP433_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004727.1"
                     /translation="MYDGELIKKLRVNKKLTQTQLAEGICSKTSLVGIETNSVKKVSF
                     GTLKSFLERMNMTLAEYEWIRNQLDEPKKLKKKRRMLDRIQEDSFDPYKEIANNRRHY
                     KKTEDLYYLVLNLHMSKKTEVSETEFEFLRYECRIIEEYLMQVPEYGQFEVSILADFP
                     WIFSDRFIENNYLKIKKRMRRIAQLNNHEQYLFTFLTNLTLFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKSENHQEFFAVIEYTLGKNQRNSL
                     EKKLLAIAKPSS"
     gene            complement(64199..66277)
                     /locus_tag="LP433_000536"
     CDS             complement(64199..66277)
                     /locus_tag="LP433_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2004728.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPATLGQTEGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTIL
                     YPVTGTNAEQ"
     gene            66770..67987
                     /locus_tag="LP433_000537"
     CDS             66770..67987
                     /locus_tag="LP433_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL2004729.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETREKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEASPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(68446..69069)
                     /locus_tag="LP433_000538"
     CDS             complement(68446..69069)
                     /locus_tag="LP433_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004730.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWEEYKLTANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLVVLLLTHDGDKVARLKNGKVVTAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     ASSQKNESTELSPSDSGSGQTITGNEENQASIITNESSEGQYQTYGQ"
     gene            complement(69225..70622)
                     /locus_tag="LP433_000539"
     CDS             complement(69225..70622)
                     /locus_tag="LP433_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2004731.1"
                     /translation="MKRYQFPKNFWWGSAASGPQTEGRISGDGKGENIFDYWYKNEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HHYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFQLFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKAYHEMDQSGVI
                     GIILNLTPSYPRDESNPEDVKAARIADAFFNRSFLDPAVKGEFPSELIERIKELDLMP
                     EIHPDDLTIIKENTVDLLGINYYQPRRIKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEKGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDRNGFEA"
     gene            complement(70644..71615)
                     /locus_tag="LP433_000540"
     CDS             complement(70644..71615)
                     /locus_tag="LP433_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2004732.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMEKISEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISNRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHAIDGLIVFLSEEEWSGFEMLTKMSIPVVALNCPGGPAGIDTIVVNDR
                     ESVAKVIAHHGGQGHKTIGFIAAAQTDYVARERLAGAKEAVQKDPSIHLEIFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            complement(71622..73922)
                     /locus_tag="LP433_000541"
     CDS             complement(71622..73922)
                     /locus_tag="LP433_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="HBL2004733.1"
                     /translation="MYDYPYQNPKLTIRQRVEDLLSRMNIAEKVGQVNQHLYGWECYE
                     KNGDKIELTEKLKEHVKWGGGLGALYGLFRSDPWSKTDYKNGIPAKESWKVANLVQEY
                     VLQHSRWKIPVLLVEECPHGHQGLDGISYPTNIGRGNTFNVALLEQSSRLMAKELAAK
                     GVHLALVSTLDLAKDPRWGRTEECFGEDPILSARFSEAVVRGFQGEIISEKVSFLDQT
                     VEEINKKKDQIGVVLKHCIAQGEALGGHNSGTVTIGRREFSDIYGPLLKSTRNAVGVM
                     AAYNDIDGIPCHINRALFEQTLRKEIGYQGIVMADGVALDRLSDVFTDKKTAAAYALA
                     AGIDLSLWDETYTKIAEAIDNQVVDEKLLDQAVRRVLSVKFLLGLFEQPFANDPKEYW
                     DHLMEESEHLNLETAKESITLLKNDGILPLDQQVKNIAVIGPNAHDVYHLLGDYSAPQ
                     TEDRLKKKIVQEIKTEFPQSKVSYAQGCEVRNQEDQEEKLLEAVTLAQNSDVIIAVLG
                     GSSARNFDMEFLRNGAVSSKGINMDSGENVDVASLSLGGYQEQLIEQLYQLGKPIITI
                     LVQGRPYDLMKIESFTNAIATAWFPGQEGGKAIAQMISGRNNPSGRLSLSYPRNSRQL
                     PVYYYQRAASKQENYYDLSGSPFYPFGHGLSYTTFEYSQMEVKTDIDKVIISIKVKNT
                     GSVSGKTSTLVYVRLIDGVVIQRTKLLKAFRKDELRSQEERLLVFELTSEDFSYMDID
                     DKRHYAKKAVIMVEQQEKEIKCNWQE"
     gene            complement(73924..75249)
                     /locus_tag="LP433_000542"
     CDS             complement(73924..75249)
                     /locus_tag="LP433_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2004734.1"
                     /translation="MKVVDRLSEKMLPIVSKMSSQRHLLAIRDSFIVTMPLVMAASVM
                     VLLNALIFSNATVQRILDLSPLAELASIVNNGTMSILAIIVCYNIGWNLATHYIQTGV
                     IDDPSFSPVHAGILSTAVMFILMSLSSTVTLMDGNTAEATGVFLQSLTSSSGLATAMI
                     AALVSTELFIKLAKMKSFKIRMPEGVPPAVAASFNSLVPEIVVILFFSVVVFTLNHTT
                     GLNVPQLIELAIQTPLKAFVLSVPGILFLQFFSDFLWVFGMHGSSILAPIRQAPLLQS
                     IQENMDAFSVGKEIPNIITEPFTNAFGLIGGGGCILPLVIAILWASKRQEQRSIAKFG
                     LTTCLFNITEPIMFGLPVVMNPIYMIPCAIIPSINLVIAYAATSLGIISKTVAAAPWI
                     TPPVIQSFIATGGDIRAAVLTVILIILDVFLFLPFVLAANKAKLAEGGY"
     gene            75480..75905
                     /locus_tag="LP433_000543"
     CDS             75480..75905
                     /locus_tag="LP433_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004735.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGADSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATVTFTKIGNYRLKDKDGNIYSL"
     gene            complement(76403..77104)
                     /locus_tag="LP433_000544"
     CDS             complement(76403..77104)
                     /locus_tag="LP433_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL2004736.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDTFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(77120..77560)
                     /locus_tag="LP433_000545"
     CDS             complement(77120..77560)
                     /locus_tag="LP433_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HBL2004737.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTITSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVLAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFEKLPVETYVGEYL"
     gene            complement(77560..78135)
                     /locus_tag="LP433_000546"
     CDS             complement(77560..78135)
                     /locus_tag="LP433_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBL2004738.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(78546..79025)
                     /locus_tag="LP433_000547"
     CDS             complement(78546..79025)
                     /locus_tag="LP433_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HBL2004739.1"
                     /translation="MFLDSGVVLKETELERIEYTDFGLGAIETEGLNLFVYENNERYC
                     GKELVLLPYQTCPEHRHPPRDENEGKKETFRCRKGLVYLYVEGKETKKLSCIIPKGQE
                     RYYTAKKEIILHAGDQYTIEQNIKHWFQAGATGAVITEFSSSSDDPSDSFTNPAIYR"
     gene            complement(79063..79542)
                     /locus_tag="LP433_000548"
                     /pseudo
     CDS             complement(79063..79542)
                     /locus_tag="LP433_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(79714..80415)
                     /locus_tag="LP433_000549"
     CDS             complement(79714..80415)
                     /locus_tag="LP433_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2004740.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQEILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(80523..81965)
                     /locus_tag="LP433_000550"
     CDS             complement(80523..81965)
                     /locus_tag="LP433_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2004741.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCMDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            complement(81979..83844)
                     /locus_tag="LP433_000551"
     CDS             complement(81979..83844)
                     /locus_tag="LP433_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2004742.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
BASE COUNT        24431 a        17532 c        14610 g        27294 t
ORIGIN      
        1 acatctgaat catcaatttt ctactcattg ataaaaaaga atccttatca atgtgatgca
       61 ccaaatgctg tacttcattc tttatcgaag aaaaattttc attgaaatta ccttcattta
      121 tcagctgagt aattttttcc aaaatcgaat cataatcaaa cggtttgatt cgatccgttt
      181 ttatcttttg atttttcttt atcaataaac tagcaatcgg caagctttct acttcggatt
      241 ccagcatatt taactgaatc aagatctcat ttttcccaat cgttaatggt tcttcttgtg
      301 ttcgactata cacatccgca caactgattt taatgatatt cttcagctta ccaatattcc
      361 cactaaaggg atgagataac attaaagaca aggcttctct tgaaacaata atatcttttt
      421 gtaaaacatc cgcttcattt tgaaaaaata attgaatcag ctctaatcgt tctcgaatgg
      481 ggcgatcttc aaaagttggc aacataacac taatttgaat acgccgatca aaggtgtcta
      541 ataaataatt ttcacctttt tccgtcgtgg cgaaaataaa acgaacctta gcagaatgcc
      601 aatttacatt ttcaccgact ggacgatagt ttccagtatc aataaataga aagagctttt
      661 cttgattttc tttcgatagg cgatggacct catcgagaaa aagatagccg ttgttggccg
      721 ttgccaataa accatcggta tccttttcag cccccgtaaa ggcccccttc ttgtatccaa
      781 acagtgttgc cgaaagcagt tcgggattgt ccgcataatc ggcacagttt aagatagcaa
      841 atggtgcatc tttttcaata atttgctcat ggatagcgta ttcaaaaatt tttgtggcta
      901 aaaaactttt tccaacaccc gtggctccat ttattaatac actgagtccg ttaggcggat
      961 atttgacagc ggctatacat ttttgaatga cctctctcag acttccgtca tgaccaacta
     1021 cagaatgaaa ggcttcgttt atttgctccg tattatctac aaccgcatat tcatctaaag
     1081 gcttccacaa aacaggcttt cccggtaatt tctcgacctt tttatcttcc actaatctcg
     1141 tcaaataatg gctggcattc tgacgagaga tacctagatt cttcgaaatt ttctcggcag
     1201 tgacagaaga catattccct gttagtcgta tcagctcatc aaaaactcga tctttagcgc
     1261 tctttttcat tttttcctcc agtttaatgt gtctaaaagc ataataaact atcggctgca
     1321 atatgtctat tctatatttg tattccaatt tttactttga aacacaaata gtcgaatatt
     1381 tgcctcagat atctgacaaa ataatttatc taccaattta gtttttatct aatatgattt
     1441 ttatgttttt tcatagctac aaatattgaa ctggattcat atattagttt tattaataga
     1501 ttacagaagg gttaagtata tttgcatagt ttccaattac tttatccttc tgtaactttt
     1561 tcaatcttag atttactagc ccgtctcggg ccctatttta caatggtttt gtccactttt
     1621 ctctggtaga aaaacgtggt agaaaaaata aaataacaca aaaaaagcgg cgtttcatcc
     1681 gcttttggta gaagattgga aaactcagat agaaaaagga cgatttttag ctctttagaa
     1741 cgttgataag tccccattct tactgagttt tgccattatc tcctatacat cttgaattct
     1801 aagaataggt cattatagat gcctaggtat ttcgatccta gatctttgta gacttcaaga
     1861 tgggagatcg tgtcatcaga tggatagaat tgttcgtccg acgaaatgtc ttttggcaat
     1921 aacgcttttg cttcttcatt tggtgtagaa taaccaatat actctgcatt ttgtgccgca
     1981 ttttccggtt ctagcataaa gttgatgaaa tcataggcac cttctttatt tttcacggtt
     2041 tttggcataa cgatattatc aaaccaaaga ttggatcctt ctggtgggat cacataatgt
     2101 aaatgttcat tttcccacat catatcggca gcttcgccag aaaatgtcac tgccacggag
     2161 gcttcttcat tgatcatata cattttgatc tcatctgcca cgattgcttt gacatttggt
     2221 gttaaatgat tcaatttatt tgctgcttct gtcagctgtg ccatattctt actattcaaa
     2281 gaatagccta aactattcaa agaaagcccc ataacttctc gtgcaccgtc aatcagcatc
     2341 aaactgtctt ttaattccgg cttccacaaa tcatcccaat gcttaatttg atttgcatca
     2401 aagaatttat cgttatatac gatccctaaa gttccccaaa aatatggaat cgaatactga
     2461 ttatctggat caaaatccaa gtctaaaaat cgtggatcaa tattatttaa tcctttgatc
     2521 ttcgaatgat ctaatggaag tactagtttt tctttgatca ttttttggat catatattca
     2581 cttggtatag cgatgtcgta gtttgtccca ccttgctgga tttttgtgaa catcgcttca
     2641 ttagaatcaa atgtttcata attcactttg tatccatatt ctttttcaaa tttcgtgatc
     2701 aaactaggat cgatataatc tccccagtta tagatggtaa gtacctttgc tccactcatg
     2761 ccacttgttt tttcaagttg acgaacacca agcagcagca ccgcaataat gatgagaata
     2821 cctaaaaaca gagattgtaa ttttttcatc gcagccgtgc caccccctcg cgtactcttc
     2881 tgtttttctt cagccgtttt ggacggtttt ctttactaat aaagtagtat ccaatgacca
     2941 atatcatgga gaacaagaaa actaacgcac ttagcgcatt gatttctaaa ctgattcctt
     3001 gtcttgcacg agaatagatc tctactgaga gcgtcgtaaa gccatttcct gtgacgaaaa
     3061 atgtaaccgc aaaatcatca agagaatagg taaatgccat aaaatatcca gctatgattc
     3121 ctggagaaag ataaggcaaa atgatatttt tgactacttg gaaattatta gcaccaaggt
     3181 ctctagccgc atcgaccatt gaatcgttca tttcctgcaa ttttggcaag accatcaaga
     3241 cgacgattgg aatgctgaaa gcaatatggg aaagcaatac actctgaaaa cctaatccga
     3301 atcctagtag tgtaaagaaa atcaagaaac tagcaccgat aataacatca ggagagacta
     3361 ataagatgtt attcatgctc aacaacgctg tccgtgcacg tcgttttttc gtgtaataga
     3421 ttcccatagc cccaaatgtc ccgatgatcg tggcgatcaa tgcagataag aaagccagca
     3481 tgaacgtatt caatacgata atgatcaaac gtgtatcttc aaaaacagct tcataatttt
     3541 cccaagtaaa tcctgtaaag ctgttcatcg ttcctccttc attgaaggaa taaaaaatca
     3601 gatagaagat cggtgcatat aagaataaaa agacgatccc taaataaaga tacgaccatt
     3661 taaatttttt catttatgag cgacctcctt ttttcttctc gcctgtcagg agcatcacga
     3721 tgaacatagc aatgattaaa atcacaccga ttgtagaacc catcccccag ttttgtgtaa
     3781 ccaagaaatg ctgttcgata gccgttccta aagtgatcac ccgatttccg ccaatcagac
     3841 gagtcagcat gaataaagaa agagaaggaa taaatactgc ttggacacca cttttcacac
     3901 catttaatga taacggaaaa atcactcgtc ggaaggtctc aaagctattc gcgcctaaat
     3961 ctctactagc actgatcaaa gaaggattca tctcttccaa tgcattgaaa attggcataa
     4021 tcataaatgg aatctcgata tacgttgcca cgaacagaaa actgaagtct gtgaataata
     4081 tctgtttcgg cccgatcccg ataaaatcaa agaaatgatt cacgctgccg tgcacactga
     4141 aaatcccaat aaatgcgtaa gctttaagca gcagattcac ccatgtaggc aaaataatca
     4201 gcatcagcca taattgcttg tgcttcagtt ttgttaaaaa ataagcagtc gggtaactga
     4261 tgatcagcgt gaaaaacgtg atcaaaaatg cataccatac agaattgatc gtcatagaaa
     4321 gcgatgtccc cgacgtaaaa taagatagat aattattcag cgtgaattgc ccattcatat
     4381 caaaaaaaga ttgataaatg atcattaata caggcgcgat cacgaataaa ccgagccaca
     4441 aaatataagg gacggaatag atcctgcgca ttgttttcat tcttgtcccc cctattcttc
     4501 gtagctgtca agacgtgcat cgaattcttc ttcagactcg ttgaaacgca tgacatggat
     4561 atcttctggc tcaaaggcca atcctacttt gcttccttct ttagcttttt tcgttgaatg
     4621 gaccatccat tcattttgct gttcatcata acagatgatt tcataatgga caccacgaaa
     4681 cagctgagta tcgaccgtta cgactagttt tcctttatct ggtgtcgtga tcgtcaaatc
     4741 ctctgggcgt aaaacaactt caactggttc atttagacgc atcccgccat cgacacattc
     4801 aaattgctta ccaacaaact caactagatt atcttcgatc attacaccgt ccacgatatt
     4861 gctctcccca acaaaatcag caacgaaatg attgattggc tcatcataaa tatctacggg
     4921 tgtaccactt tggacgattt tccctttatt catgacaaaa atctcatcac tcattgccaa
     4981 cgcttcttct tggtcatgag taacaaaaat aaacgtgatt cctaatcgtt gttgcagatc
     5041 ccgcagttca tactgcatat ctgtacgtag tttcaaatca agcgccgata acggttcatc
     5101 taatagcaat actttcggtt catttacaat tgctcgtgca atcgctacac gctgtctttg
     5161 accaccagac atttcactaa tctcccgttt ttcgtatcca ggaagctgga ccatacgcaa
     5221 agcatctttt accttctttt cgatatctga tttggacatt ttcttgatct tcaatccaaa
     5281 agcaacgtta tcaaaaacat tcatatgagg aaaaagtgca taatcttgga agactgtatt
     5341 tacttgtcgc ttattagctg gcaaatcatt caaccgtttc ccttcaaaat agatgtcccc
     5401 ttctgtagct tcggtgaatc cagctataat acgtaggatc gttgttttac cacagccgga
     5461 aggaccaagc agtgtataaa attttccttg ttcgatctca aaacttactt tttttaatac
     5521 tgtttcatca tcatagcgtt tcactacttg atcaaatgaa atgattggtt tccccacgtt
     5581 tttaccccct atattacaaa tatgattgcg ttgcaacaat caatactttt gttcgttttt
     5641 tgagatgatt ccttaattga tgttgttttg tcgcttgata atagatcgac tgtcctgctt
     5701 ttgccacata gaccgtctct cctaagctta actctaattc cccttctaat acaaaaataa
     5761 acgtttcaga taatgaaggt tcaaacgtct tatattctcc tgcaccttca aaagtcagca
     5821 agacaggctc catttctttt tcattcgaat cagccacgag ccattccaat tcatacccgt
     5881 tttcttcatc gaaataaacc gtatgatctt cttttgaata aaccacttgc agattcgctg
     5941 cttcttgatg aaaaaattct tctggagtca cacctaagac ttcaagaata gaaaagaatg
     6001 tttccattga tggtgaactt aaatctcgtt ccaactggga aatataccct tttgacaaat
     6061 ctgtgcgttc gcctagttct tcttgtgtca aattcttttg gatgcgcaaa tttcttaact
     6121 tctcaccaat ttccataatt tcctccgaat cgaagttttc taatagtaaa cttcctgttt
     6181 actaccactc gtattagtat acgaaattta ttgaaaaagg caaccctttg taaaattttt
     6241 tttgctgaat atttctttat cttttggaat aaattctagt tgtttgattc tttatttttc
     6301 acctaatttt tgtctaaatt tacggaagaa caagaataaa agagtaggct ttatggtatg
     6361 ataaaagaaa attttaaaag gagtgtctca cgaatgaacg cttttcgatc ttttcaggta
     6421 ataaaggaac ctgttttcca tacagcaatc agtgatctgc catttactga gttggctgaa
     6481 aatgaagtct tggtaaaaat tgcctattct gatgtcaatt ataaagatgc attggcaatg
     6541 agcgagtctg gtcaggtgat acgaacatat ccgatgactc cagggattga tttatccgga
     6601 actgtcgtcc aaagtaacaa tccacgtttt tcaaaagaag atcttgtact tgctactggt
     6661 tttgggcttg gcgtcaccca tccaggcggt tatagccaat atcaaaaagt accaggagac
     6721 tggttagttc ctctaccaaa aaatatgacg ctgcgtcaag cgatgatcct tggtacagca
     6781 gggtttactg ctatgttgtg tgtgaacgct ttaatccgtc aaggtatgac ctccgataaa
     6841 aaagttgtcg ttactggtgc ttctggcggt gtaggcagta cagcgatagc cctgttacat
     6901 aaactaggat tccagtcaat cattgccttt tccagaaaag aagagtctgt cacatggcta
     6961 aaaagtctag gtgctttgca agtcgtacga cctgatgaat ttctgccaga gacaacaaaa
     7021 gctttaggaa aacagcaaat cgactatgtc atcgacacag taggtggcga gcagctaagc
     7081 agtcttcttc cattgatctc ttataacggt gcagtagctt tatgtggcaa tgctggggga
     7141 atcaaactaa acgcgactgt cttgcctttt attctgcgaa acatccagtt gattggaatt
     7201 gattctgtca atgtaccaat agatcaacgt ctttctttat ggcaacagat ggcggatttg
     7261 cagattgcag atgaactggt cgtccaagag attactctgg atcaattgcc tgaaacagca
     7321 tctaaactac ttgctggaac acaccaagga agaacactag taaatgtagg tgaccataaa
     7381 tgaagattct aatcacagct ggaggaacga ctgaaaaaat cgatcaagta cgtgctatta
     7441 caaatcattc gacaggacga ttagggcaag cattagctga ttatttagct gccaatccgg
     7501 ataccacaat cgattacgtg actacgaaac aagcactgaa accgaaaaga cactccaata
     7561 taacgattta tacgatcgaa tctgcactgg acttattttt acaattagaa gaactaacga
     7621 aaaaagaaca ctacgatgcg attatccaca gtatggcagt cagtgatttt actcctgctt
     7681 ttagtttttc agaagaacag ctggcaaaaa acctacccac ttcttcaacg caagaagaac
     7741 tggacaattg gtttgcggaa aatgaacaga cagataccac tgtttcaaag atctcttcta
     7801 acaccgagca tcttgtgctc gttttgaaga aaacaccaaa aatcatttct tatctacgtg
     7861 aatggcagcc aaaagcaaaa atcattggtt tcaaactatt agtagatgta ccaaaggaat
     7921 ctcttctggc agtcgcaaaa aatagtctga taaataacaa aactgatttt attttcgcaa
     7981 atgatttgac ggaaatccat ggcgagacac accacggcta tctcttatct aaagatggaa
     8041 cagtggaaga agctcaaagt aaatctgaga ttgctgcatt gattactgag aaaattagac
     8101 tggaggaatc aaaatgaaaa agatcttact aggcgttact ggaagtattt ctgcttacaa
     8161 aagcgctgat cttacaagtc aattcgtcaa attaggtgcc caggtagatg tgattatgtc
     8221 taaaagcagc acacatttta tcacgccatt aaccttgcaa tctctgtcga agcgcgcagt
     8281 ccatacagac gtcatgcaag aatcaaatcc gcaggtaatc aatcatatcg aactagcaaa
     8341 acaagctgac ttgtttctca tcgcgcctgc tacagcaaac attatcggca agctagcaaa
     8401 cggcattgca gacgatcttc tttcaacagt cgcaatggcg cttccagtgg gaacaccaaa
     8461 attgattgcc cctgccatga acacgaatat gtatcaaaac ccgatcactc agcgtaatct
     8521 ggaaacattg agatctgtcg gctatcagga aattgaacca agagaatctc ttttagcttg
     8581 tggagatttt ggaaaaggtg ccttagctga tattcagacg atcatcgaac aggtcatgct
     8641 gactcttaat gaaagaaatg cttagaaaaa aggagtactt atgaaaaata caaaaaactt
     8701 tacattaact gcgatgtttt tagctatttt gattttatta gctgttacgc ctttaggttt
     8761 tatccctatc ggtccaatca atgcaacaac catgcatatt cctgtaatca ttgcttcgat
     8821 cgttttagga ccaagactag gtgcttttct tggcggtaca tttggactga tcagcatgat
     8881 ccgtagcaca gttatccaaa cacctttgtc ttttgtcttt tctccgttta tcccagtcat
     8941 cggaacagaa catggaagct ggaaagcctt gctgatcgcg tttattcctc gcatcttgat
     9001 tggggtggtt ccttatttcg tttataaagg tctgcgcaaa ctaatgaaac aaaaagcaga
     9061 ttccgtttct ttattcttag ctggactttc cggttcattg accaatacga ttttagtgat
     9121 gaatatgatc tactttttat tccagcaaga ttatgccaaa gtcatcggaa caaatttaaa
     9181 tgctgtttat tcagctattc tagcggttat ttttacaagt ggtatacctg aaggaatcgt
     9241 cgcaggtctt gcgactgcag cagtatgcaa tgtcttgtta agatacttca agcacccttc
     9301 tcttactaac tgatagtcat cgtagccgat ctctgatttt tttctctttt ggtgttacta
     9361 ttgaatggaa agatttgacg tcgaaaggat gatccaaatg aaaatttttg ttgtaggtgc
     9421 aaacggacaa attggccgac acctgataaa agatttagct ccaagttccc atgaaatttt
     9481 tgcaggggtg agagatgttg cttcccaaac attagtaaaa aaagagaatg tttcgtatgt
     9541 ctcttttgat ttaacttggt ccgtggaaaa aatgaccgaa gcattcaaag gcatcgatgt
     9601 attgattttt gctgccggct ctcaaggaaa gaatcttctg caagtagact tggatggcgc
     9661 aatcaaaaca gtgatcgcag ctgaaaatgc gcatgtctct cgctatctga tggtcagtgc
     9721 tgtttatgca gatgaaccag caaaatggcc tgagtccatg acagattatt atattactaa
     9781 acattatgca gatgaatggc tgaaacgaac taacttagat tttgtcattc ttcaaccagt
     9841 cacattgact aacgatgaag aagttacttc cattcaatta actaagccta atgagaaggc
     9901 atcaaaaacg atcactcgct ctacagttgc tgctgtactt gccgctctag tggaagaaac
     9961 ggatatttct cgtacgactc tagtactttc tgaaggtagc aaagagttga atacagcatt
    10021 ccaagaatgg gcaaaggagg aatagatcca tgcgtgccat ttcaatcaag catcctggtt
    10081 ctgtagatgt attagaacaa attgaagtgc ctgttcctaa accaaaacaa ggcgaattac
    10141 tgatcaaagt ccatacagca gctgtcaatc gaacagatat tatgaaaaga gaatcagtct
    10201 ctttgaaacc tccctaccct attttgggag tcgaagtagc tggagaggta gttgagaata
    10261 aaagtgatat ctccactttt actcctggga caaaagtata cggattagtc aatctaggtg
    10321 gttatgccga atatgctgtg atgcctgccg atcgtgcaat ccttctccct gatacgctag
    10381 actatgtttc tgctgctgga atctcagaag tttttttgac tgcttatcaa acactttact
    10441 ggcttggaaa attacaagaa ggcgaaactg tcttgatcca tgcaggagca agtggtgtgg
    10501 gaacagcagc gatccaatta gctagacagc tttctcacgc gaaaatcatc gttactgcag
    10561 gatcagaaga aaaactcgcc ttttgtaaag aacttggtgc agatgaattg atcaactata
    10621 aaaaacaaga ctttcaagaa gaggtacgaa aaatcactga aggtcgggga gtcgatgtta
    10681 ttttggattt catcggcgct tcttactggg aaaagaattt agcttctata gccgttgatg
    10741 gacgttgggt cttgattggt atgctaggtg ggaccatcgt gcctgagata gaccttggtg
    10801 tattgattgg gaaacgtgtc caactgcttg gtacattatt gacacctaga agtgatcagt
    10861 ataaagcaga gctcgcacaa acttttatgc aaaaagctgg gccttttcta gaaaatggca
    10921 agattcggcc aatcattgac cgtacattcc aattcagcgc agtcaaacaa gcgcatgaat
    10981 atatggaagc aaacaaaaac atcggaaaaa tcattttgaa gataactgaa taaaatcatg
    11041 ctgatcaaaa aagaggctgg gacagaagcg tttaactcca agaaataaga agaaattcac
    11101 gaaaattgct tttcaaattt ttgtgaattt cagcttattt ccgaaggaat ttcttctgct
    11161 tccgccgttt atacgtgttt agagcgtgag acaaaagtgt tctttacttt tgtcccacgc
    11221 tctttttccg aataaacggt gttcaaaagc ttgcatctgc ggtaataagt ccaaccaagt
    11281 taaaaacata agaagctgtt tttacttggc tgttcttatt acttgatgca gggcagcttt
    11341 ttcacaacct cttcactaaa cagtgttcaa tcagctgacc ctcggtatta gctcaaaacg
    11401 ctgatttcac aacctctttt tatttacgtt ctatttcatt cattttccga agcaaatcga
    11461 gctgcttgta tgcccgcttg tcgcccaaaa ataatgatct ccgcaactga atttccaccg
    11521 atccggttgt ttccatgtaa gccacctgtg acttcaccag cagcatataa ccccctaatt
    11581 ggctggtttt ctttatctaa tacttcagtg ttcgtattga ttttcacacc gcccatcgtg
    11641 taatggattc ctggtgcgat tttgatcgca taataattcg gagacgataa gtcatgttcc
    11701 atggctgtgg cacggttgaa ttgagcatct tttttctccg caacatccgt attccatcca
    11761 tcaactgttt ttgctagtgt ttcttttggt aaatcgattt tttctgctaa ttcttccatt
    11821 gtctttccag ttgtgacata tcctttttgg tcataaaatt caatagctgt ggcacgatca
    11881 cgcacgcctt ggtcaaaaat caaataagct gatttttcag gcaatgctgt aattgctgca
    11941 gatactttat cccttgtatc catttcattg acaaatcttt tcccctcttg atcgaccaag
    12001 attgctcctt ctccgcgaac aacctcacca atcaagaccc cctcatcctg ctgcacagtt
    12061 ggatgaattt gtattttatc catatcaacg gtttgtccac ctaatttttc aatcatggtg
    12121 ataccatctc cagttgatcc ttcttgattt gtcgtaatat aatcagctaa atcgggacga
    12181 tatttttcaa taaattcttt gctggcacca aaaccgcctg tggtaactac gattgctttt
    12241 ccggtgacct cttttggttc ttctccttga acatgtacag tcacttcatt gaccgtttcc
    12301 ccatttttct taatgtctgt cacatctgcg ttgacaaaaa tagggatttc ccgctcatgg
    12361 acgttattca ataacccctc cactaagtat ccaccaatag ccgagccatc agacggacga
    12421 tgtgtcctct tttcactcat ccctccagtg atcgttaagt tgtccagttt gataccgttt
    12481 tgatctagcc aatcgaccgc atcagcagag tgatcgacaa agtatcgaag catttcttta
    12541 tcattcgttc ctccaccacc ttttagcgtt tcttcataga aggcatcatt cgagtctttg
    12601 attccttctt ctttttgaaa ttttgtttct gaagcattca taccgcttga tgatttagat
    12661 gtgtttcctc cggcaacagg catcttttcc aaaattactg gattcaaccc agcatctttt
    12721 gcttcgatag ctgctgccat ccctgcacca ccagctccaa taatcacgac atcataagat
    12781 tctttcattt cttttggatc tgtatatact tgttcagaag cgcctgatga tacttcggca
    12841 gattccttcg tactagaact tgtctgcgct gtatttttct gatctgcgcc gcatgcgctc
    12901 atagcaagaa gtgcaacggc tgttaataaa ccagcaacta attttttcat ttgtatcccc
    12961 cttttctcct tatactatat taagtgattt ttttcacaat atcaactctg tttttcttta
    13021 agtcatatag ctttggtaaa cacacgcttc ttagtataat taaggatata catgaaggag
    13081 ttattttatg aatcatttga aaaccttttt tacgaacagt acaaaaactg caggtagaat
    13141 cacaaacgga atctatattt tattacgtat catcgtcgtt attatgctag tggatcaggt
    13201 ctggaaccaa cactggggaa atacaatgct tttattactg acattaattt tatttgaaat
    13261 cccttatttt ctggaaaaga tattaaagat acagattcca aatatgctag aaatcatttt
    13321 gttatctttt atttttagtt caacagtttt aggagagtta agtgattttt atggctattt
    13381 ttcaatgtgg gatacttttc tacatgcatt cagcggattt ttagctgggg gtgtcggctt
    13441 ttcccttgtt tatttgctca ataaaaatac aaaaaccatg aacttgactc ctttattact
    13501 agcagttgtt tccttctgtt tttcgatgac agttggtgtt atgtgggagt ttgtggaatt
    13561 ttcagcagat aaattactgc aattcgatat gcaaaaagat acgatcatcc agcaaatcaa
    13621 tagtgtggag ttaagtaaag acggaaacac tgtctatcat gttccagata tcactcggac
    13681 aatcattgaa agtcaaaatg cagatggtaa aacagataaa acaatcatcc aaaatggtta
    13741 cttagacgtg ggaatcatgg atactatgaa ggatttattt gttaatttta ttggagcagt
    13801 tgttttcagt gtatttggtt acctctatag tcgaaacgat taccaaaaat ttacgttcat
    13861 caagaatttt attcctaaaa aaatcaaacg ataaaacatg ctaaaaaaca agagaagggg
    13921 cagtgacaat acttttgtca ctgccccttc ttttttgaat gtatggcatg ccattagtta
    13981 tccgatagta ttaactcaaa aaagtaagat atgaggaatg actatttcgt tttttatccc
    14041 aatactgagg acttatttca ccatttcgtt atttatctaa tttacttaaa acctgcataa
    14101 ctttttcata atctggatta ggtgtgccgt ctagattttc agcaataaaa gtaaaaccca
    14161 tttttttata aagagcaatc gcctgatggc tccatgtctg tgtgtgaaga tagattggtc
    14221 cgtccgtatg gagggtagga aattcttgca agactctggc agtcaatgct tttgcgagcc
    14281 cttttccttg gtaatctggt ttcactgcta accaatgaaa aaccggatac acttgctctc
    14341 ttgatttttt tcgccaagcg gtacaggttg ctactttttc tccttttttt gtctctacaa
    14401 aaaacatcct tctttcaagt tcttcaggat aaggagcaaa gttttgttga aaatactcaa
    14461 gtgcttcatc tgtcgtttga aattccccaa cggaagtctc aatctccgcc caagcagatt
    14521 catcttcttt ttgataaaat cgaaattcaa aaccttccgc taaaggcgtg attggaacat
    14581 tttgttgaag tggtcttgtc atccagattt ctgcgtaagg taacgtttta tctaacattt
    14641 ttctatccct cctcgtctcc attatgccaa ataacatatg actcagctac ttatttgact
    14701 ataacagata gagatataaa tcagaaccag tcatctgcgt caaattcatt tcgattagcg
    14761 tatacccatg ttcctgccat acctcgcatg aaatctccta aagcagaaga aggaatacct
    14821 ccaccaggtg cgggtgttcc cggactagga agtggtactt gcggctgcag atgctcatcg
    14881 gtggaatcaa tagttgacaa gcgttttttc ttcgtttcct tctggtcatc tgattccttc
    14941 tgatcttccg actgtttagc aacaaattct ttttctgatt gttgttttat tttaggctct
    15001 aaaatttcat tttccaatcc agaaacttgt ggggccaaat gagcttcttg ccttatcgtt
    15061 ttattagatt ctgagatttt tctagatatt cttgctaact ctaggcttct tgtttgtttt
    15121 actttccctg ttggagaaac tgcatgagcc atttgttgtt ttttttctga caagctttct
    15181 tcttgtcttt tttgttcttt ttgatctatc tgtttgttta atggtaaaac atgtaatagt
    15241 gactgagcat ggagttcttg gagtgaatac gggtcatgat aactatacat aatcgtaaaa
    15301 tcacctgttt gtttggtcaa ataaccatcc tccaatggta cttcattgat tgtaaccgat
    15361 acatccttta acggtacggg tttacctaag gaatttgttg ctgattggat caactcttct
    15421 ttgtttattt tttcgtttgg atgaacaata agatcatgac cttctaatga acgattgtct
    15481 ggtatataaa cataagtaaa ggtaatttcc cctcctgatt gcttcctatt attcatcagt
    15541 tctgagtgaa gtacttcaag gatctccgac cagtgacttt ttctgtctaa tccgtttgct
    15601 tgcatccaat cagaaataga agtgactttc ccattttgtt cataagtcga taaatctata
    15661 tttggcactc gatcagaaaa ttcagcaggt aggcgcaaat caggaatacg atttacacta
    15721 ctcatatgtg tttctgcttg aagttcttta tttgtttgac tatctataaa atgagtgatg
    15781 acagtcgatg aagcagcaga tgcttctaca taaactacag ctgttgtttc tgccacattt
    15841 gatgttttcg agtctatata agttaataca acgggatatt ctcccggagt tgtagtatct
    15901 actgtcccgt tcattttgat ttcttcttta tttcctgaag ttccatcgct ttttgttaca
    15961 tattcaacaa gatctttagg ggcgtaactc tctcctgttc ttaagtgaag atcttttcct
    16021 ttgatagctg tttgatcagc acgaacatgg atcacagcag atgcagtcat tgtttttaaa
    16081 gcaattggat caaaatagga caaggaaata gtagatgttc ctgtattagt cgtatccacg
    16141 atattcccat tgtttgaaat tactttggac atatctcctt gtgttccatc tgcgttcttc
    16201 agcctttcta ccagatcaga tatcgaaact tttgtccctg ccagaacatc gattttcttt
    16261 ctttcaaact gtgaataatc tttttcatat acataagaaa cttgtgcgct tccaccgtcc
    16321 tttatatctg tcaaagcatg attcaaaata tcagtgatct gttttaactg atcacctttt
    16381 gtaggatcag tcatatcgga aaagatagaa agcggcacac tgcttccggt ttccgatgtc
    16441 cataatgttt tgttaggaat taaccagtag tggtttatcg ttggaggata actgacttta
    16501 ttataggaag tcaatgcagg aagtagctgt tttccatttg catcagtgaa agtatgagta
    16561 atagtgatag gggaatcagt ggtctcagaa acagaggtac gtacgacctt gatggtttgt
    16621 gtcgttgcct gaacgggtac atgcatatag acacctacag ataaactgat cagcatcgtg
    16681 cgcatcataa acttaacgta gtgtttttca gaacacgacc gttccttatc taaacgacaa
    16741 gcgtgtttat ttagttgttt tgaacgtctt tttgaacaca tttattctta gtcctcccta
    16801 ctcttgtcta aacatgaagt agtaattttc ataagatgat ttcattatat aaataaaatc
    16861 aaaagaagat ggactattag gagagtattt tttttgattt tttattgttt caagaaaatc
    16921 ggaataataa cttatgtact ttttaatttt gttaagtaat atatctagtt atatctagtt
    16981 atatctagtt accttttctt tgaaaaaaac ataaatcagc taataaatat gtgagacaaa
    17041 gctgccatcc ataaatacta gctgattttt tcagttaaat gtctattttt ttctctgatg
    17101 atggtatttc caaaatattc ccagtcatct ggagtcggtg gatttttcca aattatctgt
    17161 tctttattaa atttttcaag taaacaatca gataaataaa tattcgtacg agaagtgatt
    17221 cgactctcaa tcacaatatt gtaattttta aatcctttca cttgagaaat aatgtaatcg
    17281 gtataagcag atccttgcga aaaatcaata cagacatgaa tcggtgcttc aaaatatgat
    17341 accggacaaa taccgaccaa taaaaagaga taatcataaa ataagcgaat catgaaacgt
    17401 tcatcttttc ccaagaaata gcgtttattc tcttgtatga ccttttggat tgctgtactg
    17461 aatattggat acgtctcgaa gaaaaactgt agctgctttt tagacgtaaa gctagtcatc
    17521 tcaaagtcga atatccaatt ttttcgattg acatgcatca tacccatacg aagttctttt
    17581 cgtatatata gtctttcttc ttcagagatt tcaatcgaaa atggtaattg atcaatcaat
    17641 tccactgaca ttttttgact aatcatgtgg atatcatgaa aatgagcttc cgcaagtcca
    17701 aatgcgccat ctaattcaaa ttcttcttcc gtgatcaaaa acaacatgat ataagaaatc
    17761 tcatcaatga tctgctcttt agggatatga agaaaagaaa tatgtgataa atccttgatg
    17821 atcttcattc cttctgagct cttaaagtat tcatctgaaa agaaacgttt tccgattggt
    17881 tgattcccat aggccctcaa caaactaata gtggttagca aattgaattt gattcgtttt
    17941 gttgcagaca gttttaaatt gaacagatat tcaaaatatt gcacgatact ctttgcttca
    18001 ttcatgacgc tttctctaaa tggcatagaa aaaccattaa agaccccgaa atatacccca
    18061 aataatacgt tccgtatgtt tatttcttcc ccaactaata tgtttttctt taactttatt
    18121 tgatgctgtt caagaaaaga gactaattct cttcttttta cataggctct tgatatgctt
    18181 aaaaaatgat tctctgcaaa tttttcgatc gttacttttg aatccacgat ctccgttaac
    18241 agtcgagcaa tttttgatcg ttgaaagtag attcttctta aatttttgat atccgtcaaa
    18301 ttcagacgtt cgacatggat ctctgcttct tctgaaattt ggatctctgg ctttgttttg
    18361 aattcagtaa attctttatt taattctatg atataatttc ttgttttaaa tttagacaaa
    18421 cctaatgttt catataactt aggcagcact acataattct ttttctcaaa ttctaaatat
    18481 ctagctagca gcagtttttc tctatcttcc tcttctataa ggtaatccaa cttcatatcc
    18541 tacacctcaa aaaatgcctc ataccaatta cttgatatgc agatgaaagt tcatcttttc
    18601 acctatactg attttatgat ggattatgct tgttttttca tcagttattc tcatttttta
    18661 tctttttttt gagaatattg caaaaaatgg aaaaatttat gaggaaatat tctatatttt
    18721 ttgttttatt gtgttaaaat gtacaagatt tgcgccattt gcgtaaacaa ccacaaaaaa
    18781 gagcaggacg gccaccgtcc tgctctttta cttattttaa gttccattac ttattaattg
    18841 gctaaacttc tgcttgtttc tgatattgct tgtttttctc caatgatccg cacttctgtt
    18901 tctaaagaca catcaaattt ttctttgatt acttcttgga tgtgcgcaat caattcaata
    18961 taatctgtcg ctgtcgcatg atcgatattg acgatgaatc cagcatgttt ttcagagact
    19021 tgtgcaccgc cccatttcag gccttgcaat cctgcttgtt ggatcagctg acctgtatag
    19081 tgtcctactg ggcgcttaaa gacacttccg catgaagggt attctaatgg ctgttttgat
    19141 tgacgcaatt cggtcaactc atccattctt gctttgattg cttcataatc ccctgtttgc
    19201 aaactgaatc gagcttccaa tacgatagca cgtaattctt ggactttact gtgacgataa
    19261 gaaaatacca tttcgtcttt tgtcaaagtt ttcaatgttc catcttcaag caaaagatcc
    19321 acttcagcaa aaacatcttt gatctctccg ccatacgcac ctgcattcat ataaaccgct
    19381 ccaccgacac ttcccgggat gccgcaagca aattcaaatc cagtcaatga ttctgccaaa
    19441 gctgcataag tcgtatcaat cagtgaggca cctgcttccg caatgaccat cgttcctttg
    19501 acatgaatct gtttcatttc agtcagcatg atgactacac cgcgaatccc gccatcttga
    19561 acgatcagat tgcttgcatt tcctaatacc atccaaggta tatcatggat tcggcaataa
    19621 tcgatgattt gctttacttc ttcttgtttt ttcgggaatg caaggacatc agctggtcca
    19681 cctgttttcg taaacgtata gttcatcaat ggttcatcaa acaatatagt aatcgtggct
    19741 aagctttcaa ctatttcttc tttattcact gaggattttc ctttcttttc tcaaacgtcc
    19801 tcattattct atcacgctta atacaatctt gccagtcttg ttcaaagttg atgacggtag
    19861 tgatctttaa gcacttcctc acataattca tgacttctta caacttcttt ttgtttaagc
    19921 aattctgttt ccgatttacc taaacggatc tgagaaaaga aggcctctac cattggctca
    19981 aacccgcgtt tgactagcgt gtttgtccag tcgccaaatt ctttcacttt ttttccatca
    20041 gcatcttgaa tgacaagctg ggtcagatcg tttacttcat aagtaccatt tttacttgtt
    20101 acttgatatt tttctatatt agcgccactt gctaaatcca tcgttaaaat agccgtttga
    20161 ttttgtgttt ctaattgtaa aatggcatat tccaaaaatt cctttgtttc tcttatctgg
    20221 tattttgttc tcaaaatggg ttcatctaat aaatacacag ctgtatcaat aagatgtaaa
    20281 aacaaatcat aaaggacgaa ctctgtcgtt tcttttgccg ctattcgatt tttttgcagg
    20341 tggatcaacc gcttatctgg gatacgtttc aattcttcta ccataggagc aaagcgccgg
    20401 ttgaaaccga tcatcaaaat tatttggttc ttatcagcta attcttgcaa ttcacgaact
    20461 tcatttagat ggacactcag tggtttgtca atataaacat ggataccatt ttctagacat
    20521 tttttggcta attcataatg tacttttgtt gctgcgtgga tcatacatgc ttcgattttt
    20581 tcttctaaaa gctcatcgat cgtttcatat agatgttgga acccgtactc tttttgaatt
    20641 ctttcttttg tttctttatt tcttgttgca aaataaaaat caagtgttcc ttgttttttc
    20701 gcataagttg gtaaatatgc tttttctgcg atattcccta caccgattac accaatcttc
    20761 atctactttc ctcctggatc atttagttac tttcatctta caccattttt tactaaaatg
    20821 aggtacaata gtatcgcaaa ggtaaggaaa ttaattcgaa ggagtgtgct tttattgaaa
    20881 tttatctctt ggaacgtaaa cgggcttcgt gccatcgtaa ataaaaattt tttagaagtt
    20941 tttcatgagt tagacgccga ttttttctgt ctgcaggaaa cgaaactcca agcaggacaa
    21001 attgatttag atcttccagg ttattatcaa tattggaatt acgcggaacg aaaaggctat
    21061 tccggcacag cgatttttgc taaaaaacca gcattgaatg ccacttacgg aatgggtatc
    21121 gatatccatg atacagaagg ccgtctgatt actttggaat attccgattt ctttcttgta
    21181 acctgttaca cgccaaattc tcaaagcgaa ttaaaacgtt tagattaccg attagaatgg
    21241 gaagaagcct tttataatta tttggaaaat ctaaaaaaac aaaaaccagt catcgtgtgt
    21301 ggggatctaa atgtcgctca tcaaaagatt gatttgaaaa actggaaaac gaatcaaaaa
    21361 aatgctggat tcactccaga agaaagagcg gctctttctc gactgttgga taacgggttt
    21421 atcgatacat tccgttattt ttatccaacc caggaaggtg tctactcttg gtggaactac
    21481 cgattcaatt caaggaaaaa caatgctggt tggcggatcg attacttttt gacgagcaaa
    21541 gatttagagc caggactagc tgatgcaaag atccatacgg acattatggg cagtgatcat
    21601 tgtccagtag aattagattt gaaataaaga ggttgtgaaa aagtcgttta gtttcgagta
    21661 ttaagaaaaa ttttgtgaaa atggctttcc acattttgca taaatttggc ataataccga
    21721 gaaactggct tttgaacact gtttatcgag agattgtgaa aaagctgtcc tgcatcaagt
    21781 aataagaaca gccaaacaaa aatagttcct catatttttc gtttggttgg gcttattacc
    21841 gcagatacaa gcttttgaac accgtttatt aagaggttgt gaaaaagctg cactgcatca
    21901 agtaataaga acagccaaac aaaaatagtt cctcatattt ttcgtttggt tgggcttatt
    21961 accgcagatg caagcttttg aacaccgttt gttaagaggt tgtgaaaaag ctgcactgca
    22021 tcaagtaata agaacagcca aacaaaaata gttcctcata tttttcgttt ggttggactt
    22081 attaccgcag atgcaagctt ttgaacaccg tttattgaga agttgtgaaa tcagcgtcct
    22141 gacctgagta ttagagaaac aaatggcaaa atagttcctc atattttgct attttttgag
    22201 ctaataccga gggtcagctg attgaacacc gtttagtgga gaagttgtga aaaagtcgcc
    22261 tactttcgag tcgtaagaaa tttttttgaa aatggttcct cacaactttg cataaatttg
    22321 acttaatacc gagaagtcat gatccccatc taactccaaa tcacaaggaa tgagttcaaa
    22381 aactagcttt tctcaacaaa tattacataa aaaattctat gttttttgtt aaatttattt
    22441 gcttttttca aaagtatgtt acagtaattt cccaaggagg ttttacagaa atgaattttg
    22501 ttgccatgga ttttgaaact gccaatcatc agccttatag tgcttgttct cttgcgctag
    22561 tcatggtaaa aaatagccag atcgttgatg aattctatac attgatacag cctgagactc
    22621 cttttttctg gcgaaatgtc caaattcacg gaatccatca agaagacgta cgcaatgcgc
    22681 cgaaattccc agaagtctgg caaactatcc aaccatattt tcaaaaaaat cgtttagtcg
    22741 ttgcacataa tgctgctttt gatacaaagg tcttagcggg atgcttagat tattatcatc
    22801 ttgaacagcc taattatctt tctttatgta cagtgaaaag tagccgtcgc ctgtttcctg
    22861 aatttccaaa tcatcgattg aacactgtgt gcgaaaattt gaacatccaa ttagatcatc
    22921 accatgatgc attggaagat agtcgtgcat gtgcggaaat cctgctttat caagaaaaaa
    22981 aattcgggac agatccattg aaaaaacttg tgactataaa gtaaaagaat acttatgaaa
    23041 cacacaaaga ggtcgtgagc ctgccgtttc actccgagtc acaaggagca atttcaaaaa
    23101 atagcttctc atgtttatta aatattgtga ctggtgaccg aggagctggc aggagaacac
    23161 cgtttattgg agaggttgtg aaaaagctgt tctgcatcaa gtaataagaa cagccaaaca
    23221 aaaatagctt ctcatatttt tcatttggtt ggacttatta ccgcagatgc aagcttttgg
    23281 acaccgttta ccaagaggtt gtgaaatcag cgttttgacc tgagtattag agaaacaaac
    23341 ggcaaaatag ttcctcatat tttgccgttt tttgagctaa taccgaaggt cagctgattg
    23401 aacaccgttt attcaaaaaa aatggactgc gacacgactt ttgtcacagt cccttcgtgt
    23461 gtttttctgc cttctcaaaa ggatgacagt ttctcactct tttcctattt cttctattca
    23521 atcaaataac tcattttata tacatctaaa aattcaccta gatctgttct tgcccctcta
    23581 ggcatgaccg cttcgatttg gaagcccatt tttcggtaaa ggtgtacggc tctttcatta
    23641 cgaacttgaa cgtcaagctc caatcgaaaa agtacaccca tttccttcgc ccaactgatg
    23701 atttcttcta gcataagagt gcctagtccc attccccaat attcctgcag aatactgata
    23761 ccgacttctc ccacgtgaga caaacgaaat tgactgtctg ccttgacaga tgctgttcca
    23821 ataatcgtcc cttcatagat tgcaagcagc aataaattat tattgctttc gtatatataa
    23881 tccaactctt cttctaaggt ttctggtggt aacaggagtt ctgcttcatc caaaactaaa
    23941 aattctgtct ccttattaac ttgtcccatc atcaaaagaa tgtcttttgc atctcctggc
    24001 actgcttccc gcaagatgat cccaacttct tcactcatga ttttcagccc atttttctag
    24061 aattcgctgt ttgaaggttt cactttgctc cccgtatgag attagtttca cataccgctt
    24121 ttctaaatct gtatcacttt tttctaaaat cagttccaaa taatcctccg gcagtgcttc
    24181 ttctaataga tttccccatt caacaacgga aagcccatca ccttcaaaat attcatctaa
    24241 ccctaaatct gctccgctag ctgctacccg ataaatatcc atatgataca acggaatccg
    24301 accttgacta tattctctaa taatcgtgta tgtcggactt ttgatcattt gcgttatccc
    24361 taatccttgg gcaattcctt tcgtcaacgt tgttttaccc gcacctagat caccagtcaa
    24421 tatcagattg tcacctggca ttgcggaatg accaattgcc tctgcgaatt gttctgtcat
    24481 tgttaatcct gatagttcga tcatttttca tcttctcccg ctcttctttc tttttgccag
    24541 tatatcgcgt aatgaagttt ttttaaagaa aaaatgaact agtcaagaac agcagctgct
    24601 gtttttggct agttcgcgtg tatttgttaa tcaatcaatg tttgtgctgc tgtgataatc
    24661 gataatttat atacatcttc ttcatttgct ccacgagaca aatcagaaac cggtttgttc
    24721 aagccttgta gaattggtcc gattgcttca aagttaccga aacgctgagc aattttatag
    24781 ccgatatttc ctgactgcaa ttctggaaat acaaagactg ttgcttgacc agctacttct
    24841 gaatctggcg ctttcagttg tgcaactgaa ggaacataag aagcatcaaa ttgcaattcg
    24901 ccgtcgatca tgtattgtgg cgctagtttt ttagcgattt tagttgcttc aactactttg
    24961 tctacttctg gcgatttcgc tgagcctttt gtcgagaagc tcatcattgc tacttttggt
    25021 tcgatatcga acaattctgc tgtttttgca gaatctacgg cgatttcagc caattcttgc
    25081 gcagttggat tcacgttgat cgcacaatcc gaaaagacat atttttcttg atctcttcca
    25141 cgtaccatga tcatcgctcc gcttgtccga ctgatgccag gctttgtttt gatgatctga
    25201 agtgctgggc gaacagtgtc gccagtcgaa tggatcgctc cagagaccat tccgtctgca
    25261 atccccatat acgtaagcat cgtaccaaag taattcacat cttttaaaat cttttctgct
    25321 tgttctttgg atgcctttcc atttctacgt tcaacaaaag tatccaccat ttcatcccac
    25381 ttatcgtaat tatcagggct gatgatcgta aagctagatg ttttgattcc tctggcatgc
    25441 gctgcatttc ttatttcttc ttcgttccct actaaaatgg gttccacaag ttcttctgct
    25501 ttcaaccggg cagctgcgcc taaaatacga gcatcagtag cttccgggaa aacgattttg
    25561 atcccacggc gaacaatttt aaatcttaaa ctatcaaaca attccacaag atgacctcca
    25621 gacgttttta tatgtattat catacactat tccagaaaaa aagaacagtt tattttatct
    25681 gtatcagtca aaaatgctgg aaaaattaag tttttcacat acaaagcgaa ctgcactata
    25741 acaggaaagc gctgttttat tacactgttt caggcagttg ccaatcaatc ggttcttctc
    25801 ctaacgcaag gagcgcatca ttcgttttcg agaagggttt ggaaccaaaa aagccacgac
    25861 ttgcagataa cggactggga tgtggagatg ttatgatgat atggcgactc ttatcgatca
    25921 ttttgatttt ttcttgtgcc ggttttcccc acaagataaa cacgattggt ttttcccgtt
    25981 catttaattt ttcaatgatc gtgtctgtta atctttccca acctttcccg cgatgagaat
    26041 acgcttgccc ttcccgaacg gtaagaacgg tgttgagtaa aaggactccc tgtttagccc
    26101 atgacactag atttccatgt tgaacaggtg cgattccaag atcatcataa agctctttat
    26161 agatatttct taacgatggc gggatcttta cgccaggttg cacagaaaaa gataagccat
    26221 gagcttgatt ttctccatga taaggatctt gtcctaaaat caccacttta acttcttcat
    26281 aaggagtcaa ttccaatgct tcatagatat gatacatatc tggatggatc ttttgggacg
    26341 catattcttt ttttaaaaat tctcttagat gcagataata atcttttgaa aattctgagg
    26401 acaaaacttc ttgccaactg ttatgaatga tttctttcaa aaactccacc tcctaataaa
    26461 aagaataact cacattttct tcaatcacaa gggacaatct tcaccctcag cacttgatta
    26521 atatggtaaa ctaggaacaa gaagcagaaa ggaacgataa tcattatgat caaattaatt
    26581 gcatcagata tggacggcac attattagat gcccatatga gtgtttctcc tgaaaatgcc
    26641 gaggcgatac gttttgcaaa tgatgccggt gttgagttca tggtcgctac tggtcgaaac
    26701 tatcaagaag ctcgcgcagc tttagatgag gtaggaatcg attgtgcgat gatcactttg
    26761 aacggggcac aggtatttga taaagaagga aattcattgt ttaccgtgtc gattccaaat
    26821 aatcaagcaa tctctgtttt agatattcta gatgctaacg gtatttacta tgaagtagca
    26881 accaacgatg gtctttattc tgaaaatcaa gcgaaacgaa ttgaaagttt tgcttccatg
    26941 gtggctaccc atttacctca ccttacgtat aaaatggcga ttgccatggc ctcagctaag
    27001 ctggagttat tgcacatcac atacgtggac agtattcgtg ctattttgga agaaaagaat
    27061 ctggaagttt taaaaattat ttgttttcat acagaagggc cagctgtatt aggtccagtt
    27121 ggaaagcaga tttctctttt aggcgatcta gccgttactt cctctggtca aaacaatatc
    27181 gaagtgaacc ataaaaacgc tcaaaaagga attgctgttg cccatgtcgc tcacgagcgt
    27241 gggatttctt tagaagaagt catgacgatt ggcgataact tcaatgatgt cagcatgctg
    27301 caagtagcag gagtcagttt cgcaatggga aatgcagaaa tcgaagtaaa agattatgcc
    27361 aaatatacaa cggacacaaa ccttgaatct ggcgtaggaa aagccatatt gcgcgcgatt
    27421 gcagaagact tgtagtttta tctagaaaag agggatatag atgtcagaat ttttcattca
    27481 ggaaaagcag cttggacgtg caactcggac aattgtcaaa aacgaaaaag gacattccct
    27541 gtttttgatg gttggtcgct ggggaacaaa gggcgatgca ttgtctcttt atgccatgaa
    27601 tggcgatctc gttgctcaca tcaagcagat aagcctgaca ttcggtacgc gttttgagct
    27661 gtataaagag ttcgaaaagg tgggaaccat gcagaaaata ttcaattggc ccggtgactt
    27721 ttattatatt cgtagacttc actggacagt ccaaggtgat atctataatc atcaatatca
    27781 aatccatcat ttcaatcagc aaatcatgaa aatggataaa gcaacacttt tttcaggaga
    27841 ttactatgta ttggatgtct caaatgatga agatgctcca gtttgtattt gtattgctgc
    27901 ggttttagat tactggctct accgtaaaga caaaagtcgc gataagcctg tttcttaccg
    27961 acttaactta agttaaaaag atgtacctga aatgcggaaa tacgcatttc aggtacatct
    28021 ttttagatat tcttttgcat atgatcataa agatgaccac tgatcatccg ctgaccgaca
    28081 actttgaagt catggcgttc gtataatttt ttagcctttg gatttttttc atccacactt
    28141 agaccgatga cggagcgatt agctttcttc gccaatttag gtaatgcttc taataatcgc
    28201 gaaccgatgc cttgtcctct aaaatcttct gatacactga tagagtccaa ataccattcg
    28261 ttgggaaacg tttctttatc aatgaacaaa cgtgtagacg catctagctg atatttctct
    28321 aagataggta ccagtggctg atcgatgatt gattcttctt catctgtata accgtaagca
    28381 actcctgcaa ctttaccgtc tatttcttct acgatacctc gtgaataact gtaacgataa
    28441 tttggatcag tgattgcttc ttctaaaatc tctaaagtct tttgttcccc tgtctgcttc
    28501 aaaaatggca gttccatatc ttttagaatc actaagatca atggggcgat ttctggagca
    28561 tcttcttttc tcgcaaaacg aatcatagtt tcctctcctt ttctccattc taacatgcag
    28621 aaaaagaaat cgcaaaatcg ttattttaaa aaatcttcaa tcttttcagt aatgaaataa
    28681 ccatgagtaa cgattcttgc cgcttcagtt cggcaataag ggcagacgac tggcatttct
    28741 ttatcattat gttcgactac attattgact tcttcgtatg caaatttttt tccgcaatta
    28801 gggcatttca ttttttccat gttatctcaa cttcctttca tctttactct cttagcttac
    28861 tcttatattg taaaaaagag aagcaatatc cttcttctat gcagatatcc atacctgacg
    28921 gtcctgttct ccatctatta atcggacttt ataataagga cgttcatctt tgactagaag
    28981 tgtccactct ttcacttttg cttttttccc gtagtagctg actgcttcct tcatcgctgc
    29041 ttgcggttgt ttgaactctt ccgttttttc tatatcaaaa agatgttctg cggccttttc
    29101 cgtgtcattt cgtacggttg ttttcccagt ggatggattg actgctatga cttgtccttc
    29161 acaaaaaaac tggtattcat atgttgcatt cgtaggattc tccaaatctt tttcaactgc
    29221 aaaatgaata gcagatatgt tatgttcttt tgtttcgttt tttacgattg ctgctgcttt
    29281 tttcaatgag atccgatatt cctggtcact aatatcatcc atgtgaaaag cggcattgag
    29341 cagtcccgtc ataccggtaa tccctattac gatgagggca gcaacaccaa acatcatttt
    29401 tttcattctt cattctcctg tttctttttt ttaaagaata tcaagaaatg aacgaatgaa
    29461 aaatcgaatg aaacgaaaaa aaagtgacaa ttttgttatc tttattcgtg cagttctaat
    29521 ggcaatccgt ctggatcaaa gaaaaacgtc attttttttc ctgtaaaggt atcttctcta
    29581 atcggttctg attcgatccc taaggactgc aattctgcaa ttgtttcttc aatatcgtct
    29641 actttgaaag caagatgacg caagccacaa gcttctggat agtttggtcg ttgtggcgca
    29701 ttagcaattc caaaaatctc caattcagca cttcctagtt tcagatctaa tttatagtca
    29761 tctcgttctt tgcggtaatt ttctctgatt acttcaaatc ctaatttatt aacataaaaa
    29821 tcacgtgatt tctgataatc tgaaacaatg atggctatat gatggatcgt tgtaaggttc
    29881 atatgagcac tcctattctt cgtttaagct cggatctata ttaatctcca gttccattgt
    29941 aaatgtgtca gattgaaaaa aatagctgtt tttccttttt ataagaaaaa aggcaaaaaa
    30001 aacagaaagt aggtcctcca agacactctt cctgttccca atataataaa tgaaagtaag
    30061 aaattatatt ttcaagaaaa caaacagaaa attatcataa cacaaattat ttataattga
    30121 aagactagtt ttttttcaag aaaagcatac aatagattgt gttagtaaat acagaacaca
    30181 ctacatttag tgtcttaagg agtcctcata catgaagtca tattttcagt ttttagctca
    30241 tcagctaaaa ggctggccgc aacaaaatta ttatcttttc tttttcagtc ttggctgcca
    30301 ggtcatgact cttgtcaata gtcccatcac ttggctgtcc gttattacat ttatcggtac
    30361 cacgcttggt gtattgtgta ttttatccat caatgcggca aaatcagtca acggtatttt
    30421 aggtattttg tctgcgattt gttttattat cgttgggttt tcagcaaaga actatttaag
    30481 tatcggtgaa cagattgctt atatgatcac attggatatc cccgtattgt taagtaaaga
    30541 atggaatcat aatatggctt caaaaatccg aaaattcact ggaaaaagct ggtttatcgc
    30601 aatcatcagt actttccttg tctatcttgt ttcaggattc ctgattggtc gttatacaga
    30661 tgatcctcgg ccgtgggtag atgccattgc tttttctatt agcttgactg ctggtatcat
    30721 cagtttcttg cgttacaaca accaatatta ctggtggtta gcttcagggc ttgctcaaat
    30781 ggtcctttgg tatatttcat ttacgcatgg atctgcaagt ttggcgatgt tcgtgaacag
    30841 ctctgtttac ttgctgaatg atgtccttgc atttaccgtt tcaccttggt ataaccaaaa
    30901 agaacgtgaa cgtatgcaaa aaatggaaga agaatactac aacgcacaac aacacgcata
    30961 aaaaaactga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    31021 aaacggcgga atcagaagca actccttcgg aaataagctg aaattcacaa aaatttgaaa
    31081 agcaattttc gtgaatttct tcttatttct tggagttaaa cgcttctgtc ccagcctcta
    31141 ttttttatag taattccttc agatactttc ttgcctcatc attgaaacgc agtgattctt
    31201 ctaacttctg ataatattcc aacgcttgtt tctgagcttc agtaaaacga taatgttttc
    31261 ctttccattt gtcgattgtc tcttgcacat ttccagattg gatatctttc actactagtt
    31321 gccatttttc ttttgagact gtacggtctt tcttatcagc agattgtata gcttctcgtt
    31381 ctttacgcaa tacttttaaa aaaccatttc tgactatccg aggaatgctg tcgaagaacc
    31441 cttctgtaaa accatagcga caatattgct tccaaataaa tagatagatt tttggttgga
    31501 tgaatcgttg gtttttcgca aaatattcca tctgagcagt gacttctggt gttcgttgac
    31561 gttttgtctt tctcaacacg gaaataaatg tttcaaaata agcattagga tgtactggca
    31621 cttcttcata tacgatggat tgccaatctt tacgtaaaaa tgcgcgatag ttgatcaaga
    31681 attcttctac atcctttact aattcttctg caaagtcgtc aaatagttct ttttttatct
    31741 gtcgcttttt tgactgccca ttgatgtgtt cacttatttt cttgatttca ttttccaatg
    31801 cttgataatc cgctatgtaa atcggcattt ctacttggcg aaattctgcg agccgctgag
    31861 ctaattttat atccggtaaa tatggctgtt tcatccgacg attttggtac aagacaaaac
    31921 agtatttttg ccatagtcct tcaggaaaat cgatattctt ctgcttaagc cataataatt
    31981 cgtctaaggc cagatcaact tttgtcattc cctgatggat cgaagctgcc actgtcggag
    32041 agacatgcag gtgatcggca aagtggttga tgcctagttt taggatcttt ccggtttttg
    32101 gcgatttaac gatgtattgc acttttaatt ctctaccaca ctcacaatac aatttttgct
    32161 ggcttcgttt tgttcgaaaa aacggattga tcttgaagtc agaaaacacc caatctgttg
    32221 cagctaaata atgttcttcc ataaaacgag agctgattag atatcggcgg tgcttatcga
    32281 ctagttcccg ctgttttttc gttaattttg catagatctc ccaacgttga ctgcttgtgt
    32341 attgtttaga aattttgatg ggatagcttt tgctgatttc ttttggaaac cattcttcaa
    32401 agacggattg ccattcttcc acggctgttt ctttcctttc taattacaaa aagctggcta
    32461 ctaacataac gttagcaacc agccagtgtt tcttgctaaa ttagtgagtt gttccggcat
    32521 ttccggaaat atcttcttta ttttctactg ctgcttcaac tgcataagtc aaagaagaag
    32581 caatgtcttc taaagacata gaaggcgtac ccactggacg atcgatcact tgatcgggtg
    32641 agaatggcac gtggatgaac ccacctcgaa ttgccgggaa ttgtgtttcg atcaaatgaa
    32701 gcaaacgata catgatatca ttgcagacaa atgttcctgc tgtataagag atgtacgctg
    32761 gtagaccatg atcttgtaca ttttttgtca ttgctttgat tggcaatgag gtaaagtaag
    32821 cggctggacc gttttcttct aaagccgtat cgaatggctg atttccttca ttatcaggga
    32881 ttcttgcttc tgctagattg attgcgacac gttcgaacga gactgctgac cgcccacctg
    32941 cttgtccgac acagatcacg acatctggtt ggtgctgttg gatggcttct ttgactactt
    33001 gactgctttt ttcgaatacg gtcggtactt ccactttgat gatttcagca ccgctgattt
    33061 catctggcat tttttttact gcttcatagg ctggattcac tttgtcccca ccaaatggat
    33121 caaaacctgt tactagtact ttcatctgtt gttcctccgt ccgattgatt taacatatgg
    33181 ttatctttta tcataccatt ttccttgaac agcgtaaata aaggaaacaa tagtttaaat
    33241 aacataacag atcaaactta atatattctt ataaaaaaat agtgttccac tacaatgtta
    33301 gaagaggttg cgacaattat tctgtcacaa cccctctctt ctattattta aatagaatca
    33361 tataagcaat ttggaaaact agcataaata acgcaataaa caactggttt ttgatcactc
    33421 cgtatttgtc tttcatctcc agcatcgcta caggcacgat attgaagtta gcagccatcg
    33481 gtgtcagcag ggtcccacaa aaaccgcaag tcaatgcaac cattcctatt aacgctggat
    33541 tcgctccatg actaaatacg aatggtgcac cgatcccaac cgtcatcacg gtgatggccg
    33601 caaatgcatt ccccatgatt accgtaaata tcaccatgcc aagagcgtaa atgatgatgc
    33661 cgatgttcac atttccttct ggaacgatcg tacctactgc attggaaatc actgtcccaa
    33721 ctccagcgct tgtaaatacc gcacctagag aagctaaaag cattggcaac atgcttaacg
    33781 gccctactgt gcccagcata tctgctgcat catctaaaaa tgtacttggt cgattatctc
    33841 gagaaaagaa catcaagatt agcatggctg caaaaacacc gacgcccacg ccgactaaag
    33901 cacctaaatt ggtaaataga gcaaacaaga tcgcaaagac accgatactc aaagctggaa
    33961 taaaaatttt cattcctagt ttgtctgaca ttttttccat atattctttt gatggaagcc
    34021 ggctttctcc tttgctgact ttcttagcaa ttgctggtat ggtcatcgca aagatcaagc
    34081 caccgttcac gattgccgga agccatcttc ctcctgcaat aactacccct aagaccgtcc
    34141 agaaaaaggc tgacccataa cgatgaggat tggttttatc tgttaaattt cttactccag
    34201 tgtaaatcaa tacgagtccc atcacgatat aaaggatctc cagtaattta tcgcctaata
    34261 aaatatcagg atttgtaaaa aagtccatct tattgcccct ttcctggata atatttcttc
    34321 gctaatttct tttctttaag atagaagtag acacttgcca caactaaagc cgtgatagcc
    34381 actggaactt ccactaaagc aagctgtccc aatgttacgt catatcctag atctttcagt
    34441 gttgattgga ctagcaacgc ccctgctcct ccgatgaata gtacttggcc aaagaaccag
    34501 cagacatttt ccatagctga agccatacct tttagttctt cttcatgctt aggatggact
    34561 tctaaccctt ttgattcgat ggtccccaat gccatcggta aaatgattgg acgaacaaat
    34621 ccagcaactc caccaaaact cacgttaaaa gccgcaaaga tcattcgaaa gatcccataa
    34681 atatctacaa tcataccagc agatactttc ttgaatcgct tgatcaagga agccgctgat
    34741 tctttcagac catttctttc aagcgttcct gttgccaaca taatgatgat aaaaatcgcc
    34801 atcccgcgat tgtttacaaa acttgtacct aaaagttcta acattccttg aatgccaaga
    34861 ccgccagtca aagctgtaac aactaaagca accattacga tcaatatcga gtctaattta
    34921 aatgcaaacc cgagaataac aatcaagacg cctaaaaggc taagataatt ttccatatat
    34981 tttcctccat aaaatgacaa tattttttta attataaagc aaaacacata aaaaatatag
    35041 ttgttttctc acgaaataga cactattttt aaatattttt cgttattttt ttattatata
    35101 attcacctta cttattgtaa gataaagctt tttttaattt attgcctgct aatatataaa
    35161 aataaggtct agttactgtt tttttaaatg attaataaat aacaactcct ttctatgaaa
    35221 ttgcaaagca ttcatcttct tttctgctaa cgatatatcc gtcaatgctt gttacacttt
    35281 actaaaaagt atgagattgc cgatatctgg ataggtgtgc tatactacag aaaaagatat
    35341 acgatctgcc accgggtagt aaaaaagagg atgatcattc cattaggtct ttgaagggat
    35401 gattctcctc tttttgtgta ttttttatat tgaaggagga acgtatgtat ggcatggatg
    35461 gaattaatca tagcaggaat tttggaagta ttctggtcaa cgatgatgaa atggagtgat
    35521 ggtttttcta aaatcaatta ttctttttac acagtgattg gaatgattgc tagtttttac
    35581 tttttgtcaa aggcaatcaa aagtttgcct atgagtctct cttatcctat ttggacaggg
    35641 attggcgcag ttggttcggt cattattggt gtggtcttgt ttcatgataa gctgaatctt
    35701 tccacttggt tctttgtcgg gttgctgctc atcagcatca ttggcatcaa aatcactagc
    35761 ggtcactaga tacttagaca agcagacaag gactgatcag aaaaagcggg gctttttatt
    35821 tgatattcct ctttctatga aaaaacaaga aaataagact aatgacctag cgacttctct
    35881 actcatcagg tgtatgcttg tactatctat agaaaaggag tgaatatttt tgaaaagtct
    35941 ttcggtccaa gaattatcca agaactttgg tcacaaacaa gccctcagcg atgtcagttt
    36001 tagcttatct cctggcaaaa tcgttggatt agtaggtcct aatggcgctg gaaaaacaac
    36061 gatcatgaaa gctattttag gactgatcca ttactcagaa ggaacgatcc gtattggtga
    36121 aaatgagatt tctccctcta gtcataaagg attagaacaa gtaggagcat tgatcgaata
    36181 tccgggtatc tatccattct taacaggtta tgatcatctg aagttattct ctgaaacaaa
    36241 cgatgtatct gctatcgaca ctatcgtgaa acagctcaag atggaaaaat acattcacaa
    36301 aaaagcgaaa tcctactcgc tgggaatgaa acaaaaattg ggaattgctc ttgccttact
    36361 gaaccatccg tctatcgtta ttttagatga gccgatgaac ggtttggatc cacaagcaac
    36421 aagagatgtg cgaaaaatca ttaccgactt ggctactcag ggcacctctt tcttgatctc
    36481 cagtcactta ctcagcgagc ttgaaaaaat ggtcgatgag ctgatcctga tcaatcaagg
    36541 aaaaatcatc aaacaatgta caatggctga attgaaccaa acagcgcaag atttcatcgt
    36601 tatctctacg acaaatgatc aagctgctcg aacgatcttg acagacgctg gatatccctt
    36661 ggaagatcct gataaaatca agcttctaaa aaaaaacgaa gagttattag gaactgttat
    36721 ccagttattg tctgcagaaa atgtccatgt gacagatgtc cagcatctga cgaatgattt
    36781 ggaatcttcc ctattggaaa ttctggattc agtaaagggg gaagaagaaa aatgacgttg
    36841 cttataaaac aagaattatt taaattgatc aagaaaaagt caactgctgt tttatctgtt
    36901 ctattagttg ctttgctcat aggaacagca cttctagcca aaaaatacac gacgatcatt
    36961 gatccagttg aaatgactgc tcagcttttc agtgccacat cttggattgt ctttatcatg
    37021 attgctgctg caagtacgat catttcaatg gaatcacaat atggtacatt gaaaaatctc
    37081 ctttatcgaa agtattctcg aggagaaata ttagtaagta aatggatcac attagttatt
    37141 tattctattt atttatacct tttagctatt attgtcaccg tgctgatgaa actgatcctt
    37201 ttcccttcga tttcctttac ggagaagatt tctactggtc agacactgat ccaaagctta
    37261 ttcacttata ctttgggtag ttatatcggt ttatggctaa ttttaagttt agtgttgatg
    37321 attgcttgtt ttatcaatag ttccggtgcc tccatctcag cagggatcgt cttttatttt
    37381 gcttcatcaa tcatatctgg tatcctcatc gcactcattc aaaaatggga gtggatcaaa
    37441 tggaatccaa tcagtatgct gaatctgcaa aaccaaattg gcaacgaaga gattatgaag
    37501 caattgactc atctttctac taatcaaatg ctgtttggca atttagctta cattgctttg
    37561 ttcttagcat tgggatacct cgtattcaag cgaaaaaatg tatgatggtt cattaacaaa
    37621 gaagttgtga cagaagtggc cagtttcaag aaatttcggc ttatttttag aagaagctac
    37681 ttcttgaaca ccatttattc aaaaaaagaa gcgatgacac gaatgttgtc accgcttctt
    37741 ttttgaataa accacaggct tcacagcctc tctttatact tctatacgtg aagcatccca
    37801 gtggcaaata aaaccattgc gattactccg accatcgtca caccgataag taaaatctta
    37861 tctaagtgga tatgttgtac aggttcgttt tgttctttac gtgctttgag gtaaaaataa
    37921 atacctggta agaaaagaac aagaacaagc atcacttcat taaaggctac aactagcatg
    37981 gcccatactt gaaaagcact tgctaaaaac cctactaaaa attggaccca ctctttccgc
    38041 tgataagaaa gcttcatttg gtacagccct aagaaaagcc acgtgaagaa aatcgctgct
    38101 gtaccaagtg tataagcaaa gttatatgca ctgtcagtga ataataatga aagtaaaaag
    38161 acattcgtac ataacgtcgt caatacgata gcataagttg gtgccccatt tttgttgagt
    38221 tttccccatg ctttaggcaa aagtccgtcc tcagccatat tccccattgt ttcaatcggc
    38281 aagattgtcc atgagagcca aaccccaact aaagaaatga tcaaaccgcc gttgatcacg
    38341 accgcccccc atttaccaac catcatttca aatacatatc ccatagcagg ttgcgctttg
    38401 atcgtttgca gctgattcat cgtcattgtg ccatatggaa gcatggaaac caagacgtaa
    38461 ataatgatca aaccgaatat tcctagaatc gttgctttcc caacatccga ttgttttttt
    38521 gctcgtgaac ctacgacaga agctccttca ataccaacga atacccagag catcaccatg
    38581 atgcaactca atacttgact agaaaacggg atcggctgcc cattcgcatt caatatgata
    38641 tcgctagaaa agttattaat gaattgttgg atcgaaaagg tgctgatagc tactacaata
    38701 aataaaaata atggcactaa tttacaaaat gtgacgatag cattgacaaa gctagcattt
    38761 tcaactccac gattcactag ccatgcatat ccccataaga agatcgtact catcacgatc
    38821 gatgccacat tttgaccacc ttcgaatacg gggaagaaat aacctaatgc actcatcaac
    38881 aatgttgcga acgccacgtt tcctaaccag catgtgagcc agtaacccca accgctgata
    38941 aaaccagcga aacggccaaa accttcttct gcgtaactaa agatcccgcc ttttaaatct
    39001 ggacgttttt tattgatatt attgatcgat aaggagagca tcaacattgc tgttcctacg
    39061 agtacccagc tgaagatagc tgggccacca gccgatccgg agatgtccgt cataatacca
    39121 aatacgccac ctccaatcgc tgaaccaatc actaaggcag caagtggaat caaaccaatt
    39181 ccttttttct gttgctctgt atccatgtaa gcatcctcca aagtaaaacc gcttttatca
    39241 aaaagtataa caaacctttt ttatttttac ttaattaata aaaactttaa tagaaatata
    39301 attctaccga cttttttctc attatacaag caaagcgcct agtccctttc caaattacac
    39361 caccaaaaaa acttaaaaag atgctatact aaagggaaag aattggggga tgatccatga
    39421 acattttata tatatcgatt tcaggaaata cgcgtgcttt tgccaaacat ctagcagaat
    39481 atgctgaaaa aatgcatgca gaagatcctg tcaatcctga agttacttta aaagaaatcc
    39541 atgaaaatag tgattttacg aaagaaacag aaccattttt tactttcgtt cctacttatt
    39601 tagacggcgg gaatgggtta gacaacggtg acacagaaat cttgaccgaa acgatgcgcg
    39661 aatatctgga atacgaagac aatcataaac tttgccttgg tgtagtcggt agcggtaata
    39721 aaaacttcaa caatcaatat tgtctgacag ccaaacaata cgcacaaaga ttcggctttc
    39781 ctttcttggc agattatgaa ttacggggaa caccatctga tgtgacacgc gtttatcaaa
    39841 ttttggcaga aaaaaataaa taacacaaaa gaagaagctg aaaaataaat ttcggcttct
    39901 tctttttatg ttctctattg tttctattct tattaagctt tgacatccat cacaggtgct
    39961 tttgctttcg ctttacctgt tttttccaag acaaagtttt ttacacgatc catattggtt
    40021 accaagacga tcatggaggt ttctttgtct gctgctttga ttgcttctaa gtcagcttct
    40081 gctacaagcg tatcaggtgt cacttgctgt ccttctgtta ctttcacatc gaatggcgta
    40141 ccgcctaagt caactgtgtt gatgcccatg tgaagcaaga tttctaagcc atttggtgtc
    40201 gtaatgccga tagcatgttt tgttgggaaa acagaactta ttactccagt aaccggggaa
    40261 tagatatgtc cgttttctgg ttctacaaag taaccttcac ccatcatttt ttgtgcaaaa
    40321 actgggtcac ttgctttatc taaagaaaca actgttccgt cagcaactga tgataagata
    40381 gtcacacttt cagctgaagc ttgaggtact gctttttcag gtacttcatt tactgtggct
    40441 gtttcggtcg ctagttcttc tttttctaaa cggtctttag gaataccgaa gaagaatgta
    40501 gcaacgaagc caccagcgta agcagccaat aaaccaagga tatagcctaa ccatttacca
    40561 tcagagatca atggaatcaa agcggctcct gaaggtccaa tagcgattgc tccgacattt
    40621 ccgatcattc cgatcactgc cccaccgata cctccaccga tacaagcagt aataaatgga
    40681 cgtcctagag gtaatgttac tccgtaaatc aatggttcgc cgattcctaa gattccgact
    40741 ggtaaagccc ctttgatcat ttctgttaat tctttgtctt ttttgcagcg gatccataat
    40801 gccaatgctg cacccacttg tcctgctccg gccatcgcaa ggattggaag caataaggta
    40861 cgaccagttt catcaatcat ttgtacatgg attggcgtca agatctgatg tagtccgaac
    40921 atgaccattg gcaagaataa tgtacctaga acgaagccgg caaatgctcc tccaacacca
    40981 agtacccagt tgatcccacc gaccatgccg tcagaaatga accctgctaa aggcatgatg
    41041 aagaaaattt cgatcagacc gatggcaatc agggaaagag ttggcgtaac gatgatatct
    41101 accgcatcag gtactacttt atgcagtttt ttctcaacga ttgacaataa ccaaactgcg
    41161 aagataacac ctaagatccc gccttgtcca gttgcaagag cttcaccggt aaacaagttt
    41221 ttcagtggtg cttctggatt catccctgtc agcatcacaa cagccccgat aactccacca
    41281 agcgttggcg ttgcaccaaa aacttgtgca gcattgatac ctgtatagat aactagatag
    41341 ctaaacatcc cgtttttcaa gatgttcatc acatcgatat attgttgcca tgttcctgcg
    41401 tctagtgttc cagctgtgac taagtttgct aaaactgcgg caatccctgc cacgatccca
    41461 gtgccgacaa atgcagggat cattggtaca aagatattag agatgtcttt taataccgat
    41521 ttgattttag agggtttttg tttcgatttt tgtgccgctt tcatttcttg tgcccgttcg
    41581 tttacacggt cttttccaga tgcagaagaa cttgctgtag ttgcactagc agaaggaagt
    41641 ttttctccta atttcacgcc tgctaagtca accatttcct gcgctacttt gttcactttc
    41701 ccaggtccga tgatgacttg gagctgttca tcctctacta cgccaagtac tcctggaatc
    41761 gcttttaatt ccgagacatt tacaagatca tcattgatga ccttcatacg tacacgagtc
    41821 atgcagtgga caatgctttc aacattgccc ataccgcctg ctccttgata aatttgtttt
    41881 gccagttctt ccaaagtcaa ttcgtttttt gccatggtct tttccccctc ataaggttcc
    41941 ttttacaaaa ccgtttgctt cagctaattt tgcttgagct gcctctttat cactatttgt
    42001 caaaatcatg acgatagcca gtttgacatt ttgatctgct tcctcaaagt acttttcagc
    42061 tgtttcgtag tcagcttctg tcgcttgcat gatgattcgt tttgagcgtt caattagttt
    42121 ttcatttgtt ggtttgacgt cgaccatcaa gttattgaat actttaccga taccgatcat
    42181 actgatagta gaaatcatat tcaaaatcag tttttgtgct gttcctgact tcaatcgagt
    42241 agagcctgtc aaaaattctg gtcctgcatc gacttcgatt gggaaatccg catgctcgct
    42301 gatttctgct tgtttattgc aagaaatcgt tcctgtaaca gcaccaatcg attttgcgta
    42361 atctaatcca ccaatcacat atggtgtacg accgctagct gcgataccaa taactatatc
    42421 attttttgtt aaattcagct tgattagatc ttcttgccct aattcataag aatcttcggc
    42481 tccttcgacg gctacagtca ttgcttcttc tccaccagca attaggccta tgaccatttc
    42541 cggttctaca ccgaatgtcg gtacacattc agcagcatct aatacaccaa gtctaccact
    42601 cgttccagct cccatataaa tcaagcgacc acctttttta aaggattcaa tcgtgttggc
    42661 gatcactggc tcgatacttg gcagttcttt ttcaacagca gcggccactt tctgatcttc
    42721 tttgttcatg agttggactg cttgagaaat actcatttca tctaatccaa aagtttcttg
    42781 gtttctgcgt tccgttgtta ggttctctaa attgattttg ctcattttta tcttccttct
    42841 tttcttataa attgatagtt cataccagct ttgatttggt tgatcagcgg tagttcttct
    42901 ttgatgactt tggctactac attcactttt tcatccgctg gcaaatcata tttagttaat
    42961 tggatctcac ccatatagcg caaatacttt tcgttatcta aagtaataga tcctttcata
    43021 cgcttagctg tatttcttac tgggattggc ggaatctctc gaaaacgcgc atctgcgctt
    43081 cgtatgacat ctcttgcatc atcttgccga ttcgtatgtt ttcctaatat atattcgtaa
    43141 aaaacttcat ctacaggttc cgtatggagc aagactgtct gttctttttg gaaagaagca
    43201 aattgctcct gaacgtgttc tgacagacct gcatctccga tataaacaat atccgtgtta
    43261 cttgctaata gatcaagagc acctgccaga ggatggatcc ctcgatgttc ttccaaagtt
    43321 ggtaatcctt gatacagtgg acctctcaac tctgtatctc ctggtacaaa gccttgtaca
    43381 aggaatcctt gagttttgag ccattgattt ttttcctgat accattcttt gtccaaccct
    43441 gtttcaagac gtggataata attatgccaa gcttcaatct gtgagaaatc agccgctgct
    43501 tctttcaact catcgatatc attaggcgtg atcgtgctgg cattcaaact gattttcaat
    43561 tgatgtgacc agtcggcgat ctgctgatta gaaatatgat aatccattct taaccctgtt
    43621 acaccaattg ctttcaaggg tgttagatct tctaatgaaa agccagctcg tttcaatgcc
    43681 tctcctgaaa tatcgaccat caactctagt ttattctttt tcgcttcgct tcctagttcg
    43741 atcaatcgat tttgataagc cgaaacatca tcttccggta tatgcatgga agtgaaaata
    43801 ccgacaaagc cattggatgc catttggcgg atatactgtt tcttctcttc tgacaaagaa
    43861 tcattcataa atattgaaaa gccaaacata ttatccctct ttttctgtat ccgtcttcat
    43921 ttctatgact agagtatata tctaaagaaa caaaatttca atacttttgt taaaataatt
    43981 aaattttatt tctaaaaatt ggatttataa tgccaaaaga attgacacag ccacaaaaaa
    44041 ggcactgcta agcaaaagca gtgccttgaa acattttatt taaataacac aaaagtctaa
    44101 ttactcataa gaaattaatt ctgtattgtc taccatgaat gtaaagaacc cttcattagg
    44161 cattggatga aaataagcat tgatcactct tatcaaggca ttatgacaga ctaacaagta
    44221 gacattttct tcgtcttcca tgcattcttt caataaagga acgatccgtg cgtacacatc
    44281 taagaccgac tctccatttg ggaaacgtac agcaaacgct aaacgcgctt tttgaaagtt
    44341 ttcatctttg cttggcagtc cgtcataatc cccaaaatcc atttctacca atcgctcatc
    44401 agcggtcatc ggcaaattga gacgatcaac tactgcttgt gctgtatctc ttgctcgttg
    44461 aagaggggaa tggatgattt tcgtgattgg aacaggcaaa tctactacct tttctgctag
    44521 tgcctgtgcc tgcatctgtc ctttttcagt cagcggcaca tctgctcgcc cgcaaactaa
    44581 tccttgtgcg ttccaagttg tttctccgtg tctcgttaca taaagcatgt gattctctcc
    44641 ttcgttgaca aagttctcct taaccatacc ttgttgtctt tgagattaca aggtttagat
    44701 tttctcaaga gaaataatct cagtagatac tttatctaga aaggtttgat catgttccac
    44761 tagtaacata gcaggtttca cgttcaaaat cagttgttct aattgttctt gattgaagac
    44821 atccaaataa ttcaatggtt catcccatat atagagctca gctggttggg ataaagattt
    44881 agccaattcc acttttttcc gttgtcccat actcatctgt tcgattttat tatgaaaaac
    44941 atctctttcc atcccaagct ttcggagatt attcaaaaat gcttgatagt ctactcggtt
    45001 tttcttcgcg aattccgcca atgtccctcg attgtcttca taattttggc gtacgtaact
    45061 aatggtcaaa tgtttgggct gggatttttc tcctacaacc ttgccgttga atgtccccag
    45121 aagataatgg ataatggatg actttcccgc gccgttagga cctgaaattg ccatccgctg
    45181 atgaggttcg atcgtaaaat gaactggctc gaataacaga ttttcatacc ctaattgaag
    45241 attttctacg cttaacagcc gtttatgatg agacacttgg ctattcatcg tcaaagcatc
    45301 gatatactcg atatctttta ataatttttc tttctcactg atctgggttt ccatccgatt
    45361 cacgattgct ttagatcgtt tcatcgtccg tgcagcatca gcgcctactg ctcctttatt
    45421 cactcgccta gattccgtat cgatgaatcc gacttttttc tttgttttgt ccccttctcg
    45481 ggaacgagac cattctgctt tttcagctgc tgttttcttt agcctgctga cttctttttt
    45541 caatttttca tttttagcta tttcaaattc atcacgaagt tttttctgtt cttcatagat
    45601 agagaaattc ccttgataaa gttccagttg gctcttttcg attgctaaaa catggtccac
    45661 tacttcatcg ataaatcccc gatcatgact caccacgatg aatccttgtt ttttcttttt
    45721 caagtaagcc gctacttgtt ttctgccaga gatatccaaa tgattcgttg gttcatcgat
    45781 taacgggaaa tgagtgtcat ccacaaataa gagtgccagt aggacttttg tcttctctcc
    45841 tcctgatagt gtgctgaatt ctctccataa gatttcagga tctgtttgca tcagttggag
    45901 ctctctttca atttcccata tctcaaaatc cataatctca tttaacacat aataggtcaa
    45961 acgctcttta tcttttgttt gctgcgggaa atagacaaac gcttgctgat ggatcacttg
    46021 cccttgataa gggagtttgt tttgcaggat attcagtaaa gttgtctttc ctcgaccgtt
    46081 tcgtccgata agtcctagtt tccattgtgt gtcaaagttt agattggctt gttcaaataa
    46141 taatgtgcct tggctgtcat agccgaatgt cagatttttt atttcgattt tagacattat
    46201 tccatcacct cgtaaaaaaa gaccagtcct attttcagaa ctggctaaag aggatgcaag
    46261 ggttggggca cacaaaaaga cccatacatc gaaagaacca agccaatccc gaaaatctgc
    46321 acactgctcc cttgtctcca caaggtacag tctgaatgca gctttcatca atcgacttaa
    46381 tttttcaatg cacggatccc tcactttgtc ctatatttga aattacgata gcataaagaa
    46441 attgtttttg tcaactactt cgggagaatg ttgaaaaatc tgctgagtgt ctgtcctaag
    46501 atttctgttt tttctaatgt ttgcctgtgt tccattgctt cctctaaatc gattggtcct
    46561 aattgaatgc ttaagacaat ggggagaaaa tcaaagagtc cttccagctc tcggtctcta
    46621 cttccgcaaa tagcgattat tggttttcga tatttttttg caagcactgc tacgccatat
    46681 ggaacttttc cgtggattgt ttgctgatca atccgccctt ctcctgtaat gatgacatcc
    46741 gcttgttcga tctgtttttc taatccagtg atttggctga ccaactcaaa accagagacc
    46801 atcttcgctc ctaacaaaaa aagggctccg ccaataccgc ctgctgctcc gcttcctggg
    46861 atgtcatcta aatccacctc ccaaacatct tttatctgct gagcaatctt ttcagcttgt
    46921 ttatccaaga aagctaacgt cgtatccgtt cctccttttt gtcttccaaa ttgccaagca
    46981 gctccttgtt gacctgtata tgggttggtc acgtctgcag cgatgatcac ttttacttta
    47041 gaaacaagaa cgttccttcg atccaaatga agttttctag tagataacaa aggatttcct
    47101 tctgtgtacc cttctaaaga agcacccaaa gattggagta atcctagacc accatcgcta
    47161 catccgcttc ctcctaaagt gacaatgatt tgttccactt cttgaagcag tgtatctttg
    47221 ataagctctc ccaaggcata actagaagca agtcggatgg tttgatccgt tggtttatca
    47281 agtaaatcta atcctaatac ttgtgcagat tcaatgactg cggtattttt tccttgccag
    47341 ttcgtcaata aataactgat ttttcgctga cgaaataaga gatccatccc atcaatcgta
    47401 cgccaggttc ccccgagcgc gtaatagatt gcttctgcag tattttctcc gccatctgca
    47461 atcggcacat tgatttttct tcctttacgg tcttcccaac catttagaac tgcctgattt
    47521 aattcaaatg aagaagcact tcctttaaat gaatcgattg ccgccaaaat atccatctat
    47581 atccctcact ttcttcttaa gtaagacact ttttttcact tttttcaaac aaaacaatgc
    47641 tattttcttc tgtttttcta tatactaaaa gggaactcat tgaataaagg agagaaaaaa
    47701 catgaaaatc gcaatagctg gagccggagc aatgggcagc cgaatcggat taatgttgca
    47761 tcaaagcgga aatgaggtcg tcttgatcga tcgctggcct gctcacattg aagccattcg
    47821 tacaaatgga ttgattgctg actttaatgg caaagaagta gttgcaaaac tgccaatcta
    47881 ttcaccagaa gaaatcatcg aaagcaacaa acacgtggat ttgatcgtag ccttgacaaa
    47941 agcgaatcaa ttagatgata tgtttcgttc gatccaatcc attattactg agaatactta
    48001 tgttttgtgt ttactgaatg gattaggtca tgaagatgta ctggaaaaat atgtaccaaa
    48061 gaaaaatatc ttatttggga tcacgatgtg gacagctggt ctagctggtc ccggaaaagt
    48121 cacattatta ggtgatggag aaatcgaact agagaacttg gaaccagaag gcgaagcatt
    48181 tacaaaaaaa gttgtagaag tctttcaaga agcaaaattg aatccaatct atagtcataa
    48241 tgttcgttat tccatttggc gaaaagcttg tgtaaacgga acattaaatg gattatgcac
    48301 gatattggat tgtaatattg ctgaattagg tgcgcaaaaa gcggcagagg gcatggttcg
    48361 aacgattgta tctgagtttg cttctatcgc agcaaaagaa ggaatcacat tagatcaaga
    48421 agaagtgtac caacatattg cttctactta tgatcctgac aacatcgggt tgcattaccc
    48481 atctatgtac caagacctga tcaaaaacca tcgtttgact gaaatcgact acatcaatgg
    48541 tgccgtttgg cgaaaaggac aaaaatatga tattgctaca ccatattgtg cctttttgac
    48601 ccaattagtc catgcaaaag aaggaatcct tggcgcagaa taaaaggctc tctgatgaga
    48661 atcagctgga tcagcagctg gttctcattt ttttaccccc atgaaagttc aaaaagaaaa
    48721 acacaattct catgttgcca taagaattgc gcttgtttat tttcatctat gattggttgg
    48781 cacttttatt tatttttaac agaggaaaga tcgtattcat attgttcata aatagcggag
    48841 tcagtagtga aaaaacgttt tgcccaattt tctgcatcaa aaaattccaa cagttctgat
    48901 gggattggtt gaaatggcgt atgcaaaaat tccggtaatt catctaaatc acgttcttga
    48961 agcaaaaaaa tattttcaga atgataaaac tgataatgag ctatggcttg attatctgtc
    49021 actagtttct tttgaaaata catagattca aacgttcgca aagtcactcc ttgctgccct
    49081 tcccgcaaca gttctagaat ccccctcgat tccccggttt ttttcagata ttcttcataa
    49141 gtaaggtatc caggttgttc atttcctcga agcggaagaa taaagtaatt ggtcgtaaca
    49201 cctctttttg taaattcctg cttatatttt tctgcccgtt cttttctgcc gttatttgtt
    49261 gcaccaaaaa atagatccgt ctttggttcg ctagaagaaa aatccatatg tttcgaataa
    49321 aaggaactat tatgttttag tccaagttct ttcgcttcta aaaaatcaaa atgataaatc
    49381 tcatcgattg ccggttcatc ttgtgcctgc ttcagcatcg cctcgtgttc tgctttaaag
    49441 tggttccaaa aaaataacac gatttttgca ttggtaaatg gacgcacgcg tcgagccatc
    49501 tccatatcaa atccataatc taaaaaaacg atcagctgat aatttgccaa ctgttgtcga
    49561 gctgatttaa tgaattccga ctgtagtaaa tcttttccgg accaaacatc taaagagcgg
    49621 atggaaggaa aaaaataaag tgatttattt ttcgcaatta gcaatacgtc gtttttgttc
    49681 atctgttccg cctcactttc tctgtcactt tttcctatga tagcctgttt aaatagtaaa
    49741 aagccagtaa aacgcttcct attattttta taaaaattta acatttctat gaaaatacga
    49801 tgaaataaat cattcttcca ttaaaatatg cccaaaagtt ttctgaatag ttgtaattat
    49861 ctgaaaattt gttatcatta gtcattatta ttattactat ttattcttac tatttattct
    49921 tactatgcat tttgattgtg aatttaaaag aaagaggtta tttatggaag ataaaaaatt
    49981 gaaaaaacaa cttagctccc gacatatcac catgctagct ttaggtggag cgattggtgc
    50041 aggtctattt aaaggaagtg gcgaagcgat tggaatcgcc ggcccttctg tattgatcgc
    50101 ttttttgatt ggcggcataa ttttatatat cgtgatgaaa ggtctgggaa aaattgtttt
    50161 aagtggtggt gatacgcacc acggattatc tggattgatt cgtccatatc taggtgctca
    50221 tgctgccgat tttaccgatt gggtctactg gtccatgtgg attatcaata tcattgctga
    50281 agctgttgca gctgcttcct ttttacagtt gtggttcccc cacatcccag cttgggtatt
    50341 tgtttttatg ttggctgttt taactactat catcaatctt tattcggtac gattattcgc
    50401 agagacagaa tattggctgg cctttgctaa aatcagtgtc attatcctat tgatcatttt
    50461 tgctgcttat cttgtcggtc agcaaatgtt gggtactggt gttttcccta cccttcaaca
    50521 attaactgat catggtggtt ttactcccca cggtatgaag ggaatcatca gttctttgct
    50581 tgtagttatc tattcttacg gcggttctga gttgattgct atcacagtaa gcgaagcaga
    50641 tgatcctaaa cgtgcgattc ctaaagcaat caaaggcgtc atgggaagaa tcatttcctt
    50701 ttacattatt cctttatttt tgcttttgat tatttttcct tggaatactt tagcaggcac
    50761 gaacgttagt ccttttgtga tggtatttga aaaaatgaat attccatttg cggcagatat
    50821 cgtcaatttc gtgattgttc ttgctctgtt ctcgtctatc aattcaggtg tatatgcttc
    50881 ttcgagaatt ttgttcttcc gcttgaaaga tcggaaaggt tcctctagaa aactagctgt
    50941 tttaaacaag catcaagtac cgcaacgtgc tgtgctgttt tgtaccagtg ttctttatct
    51001 aggtgtggct ctttcttatt ttgtcggtga caaattattt ggctatctgg caggttctct
    51061 ttcctataca gtattattga tctggatcat tatcagtgct gcgtcctttg tactgacact
    51121 aaggaaagga acgttatggg acaaaggaat cagctttttt gcattagcag tcttatggtt
    51181 gattttcctt ggtatcctat tcacgaactc cattggggta actgtattga ccggtttgct
    51241 ttacctgttc atttatttca gttatcaaaa aaagaatgat gctttcgtct tgacgaatga
    51301 atgaaaccaa tagagaattt tattctattt atattgaata tctggagcta ttgaaaaaaa
    51361 ggagctgcga caaaaattgt tgcagttctt ttttccgaat aaacggtgtt caaaaaccat
    51421 ctgtgcagat taattgattg ttctccacgc tcatgacatg atagaagaaa ggaatgaaga
    51481 aaaaggagtt tgttttaaat gaaaaagtat tggaagtttt tgttgatgat tggtgtttcg
    51541 acggtagtca tgtttggtat gatgtatttg aatgtttatg cgcttgatca tatcttcttc
    51601 agtcgcacac gtgtattcat ggcgttgatg atgggtgcag tcatggcagt catcatgttg
    51661 ttgttcatgt ggaaaatgta tgaaaacaaa aagataaatg ctatgatttt agccgctagt
    51721 cttcttgttt ttgccggttc cttatttatg gtacgaagcc aaacaactgt caacgatacg
    51781 gcgtggatga aggcgatgat ccctcatcac tctattgcta tcttgacaag taaacgagct
    51841 gatttaaaag atcctgaagt aaaaaaatta gcggaagaaa tcattcaggc acaagaagaa
    51901 gaaatcgaca aaatgaaaaa aatgatcaaa gaaatggaat gaccattatc catccaaata
    51961 aaaaaagagg atgttccaga agtgatcaac ttcaagaaat aagaagaagc tacttctgga
    52021 acaccgtgaa tcagaggttg tgaaaaagct gccctgcatc aagtaataag aacagccaaa
    52081 caaaaatagc ttctcatatt tttcgtttgg ttaggcttat taccgcaaat gcaagctttt
    52141 gaacaccgtt tattcgtaaa aagggagtgt gacaaaagtc ttgtcacact ccctttttac
    52201 gtttttattg ttctaattgc gctgtcttgc ttactgcttc ttgcggtttc acaaatttct
    52261 ttgagatccc ccaacctgta aaggcactga ccatcgaaaa cacaggtgaa agcaaactga
    52321 aaaacatgaa tggcaagtaa gtgagtgtag gaatgccaaa tgtacttgct acgaaacttc
    52381 cggcgattcc ccaaggcact aagtagttga ttactgttcc accatcttct agtgttctcc
    52441 ctaatacagt tggatcaaat cctgcttttt cgtaagtttc tttaaatgca ttaccaggca
    52501 ggataacaga tagaaattgt tctccaataa agatatttac tccgatgctt gtcatcaatg
    52561 ttgtaaaaat caattttggg gtgttcgtca tctttcttga tactcgttcc ataacggttg
    52621 agatcaaccc aaattcgatc aacaaaccac ctaatgacaa tgttagaata atcaatgaca
    52681 cagttggcat catgctttcg attcctccac ggctaagtag tgaatcgatt tgttggtttc
    52741 cagtatttga aacaaatccc gattcgatga cccctgccaa cttcgttaag gaagtttgtg
    52801 ggttttgaat aaagatcatt cctactgcta cagcaatatt caacaaaatc gtcaaaattg
    52861 ccggtacctt tttccatgca cacaagagca ttaaaaatag aggaatcagt gaccagatcg
    52921 aaatagtaaa gtttgcttct aaaatatcag tcacttcacg aatagatgaa agacttgcgg
    52981 ctttacttgt gtgtcctaaa atcatgaata aaaagaaaga aacaacaaat gccggaacag
    53041 ttgaccacat catatgcttg atgtgtttga acaaatcggc atcaacaata gctgctgcta
    53101 aatttgttga ttcggataat ggagacatct tgtctccaaa aacggcacct gaaacaatgg
    53161 ctccaacaac aagggctgga tttagtccta gtgttgtccc aataccgaaa aatgcaatcc
    53221 caatcgttga cataacagta aaggcactcc ctacagcgct acctacgatt gcacaaacaa
    53281 caaatacaga agggacgaac cactggacac taatcaattt aaatccaatg accatgaggg
    53341 ttggaataat tcctgcttgt atccatacag caatcaatga accgactaaa ataaaaataa
    53401 agattggaat gatccccggt ttgatgccat tgatgatccc ttcgtgcagc caatctgtcg
    53461 ggtatttttt tatcactgcg tacaacatga ccattccgat agctgccaaa atcgtgatat
    53521 taggtgaaac ctttaatccg acaacgccaa tcgcaatgcc taaaacaatg accatcaata
    53581 caagtgttgc ttctaaaaaa cttggtgttc cttttttttc catgataatc tctccttttt
    53641 tagttgttct tatgttctaa aaaagttaag atatcggatt actccgccac aattcatccg
    53701 cgattcctcc tttataaaaa taaaaagacc tgctttcaac taaggacgaa tgactccgcg
    53761 gtaccacctt aattaaaaac agatctgttt ttcactttca aacgattatt caaatgtatg
    53821 gactttccat gtaattcgtc aattaggctt gatcggttca cagcgaccac cgactttctg
    53881 aacaaaacac ctaaccacta ctgcgtgaaa agttgacttg tatgaagttt accttccata
    53941 agatcatttg tcaatgaaaa agaaaatatt ttttcatttt tctgaaaatt atttttataa
    54001 ctttcgcgca caactttatc tttttactag aaagtagcgc cctcttgttt ttttcttgct
    54061 actatttctt gatgttcttg tttgattttt tctaatagct tgggttctct caataaatct
    54121 agagctgtat tggcaagtaa ttccgctgca atcgcaatag aagcaagtcc tttttcactt
    54181 ttagcagcag ctttgaattc ttctgtatgt ccggcaatat atgtctcaga gattgctaca
    54241 gtaggctgta tcgttggaat aacttggcta acatttccta catcagaaga acctagactt
    54301 gttctttgtt ccgtttctat ttcttcatca ggaacccctg cttcttttgc atgttggaag
    54361 aataagtcat cgaaagaagg cgttacgatg acatcatcga ctgcattttg gaacaatcca
    54421 aactcaaaag tcgtacccgt gcttaatgca gcacctcgta cgatattttc cactttttca
    54481 tatactttgt ctaatgtttg tcgatttcct gcacgtaaat agaaacgtcc agcagcgtag
    54541 tctggtatga cattggccgc cacgcctcca tctgtaatga ttccatggat attgacatct
    54601 tttggcaatt gcaagcgtag agcgttgatt ccgttaaaca cttggatcaa ggcttccaaa
    54661 gcatttactc ctttttcagg tgctgctgct gcatgagaag cgacaccgta aaatttgata
    54721 tcgactggat catttgctaa agattctgtc gttttcccat aacgaaaagc tggatggaca
    54781 cataatgctg catcgacatc ctcaaaaaaa ccttcccgaa cgaagcttcc cttagctgat
    54841 ccattttcgc ctccttcttc ccccggagta ccatacacac gaatttctcc gccaatctca
    54901 tcaatgaatt gtttcactat gctggctgct aatacggagt aagtaccaaa taaattatgt
    54961 ccgcatgcat gaccaatacc tggtaaagca tcaaattctg ccaaaaaggc aattgtcgga
    55021 cctggtttat tggaaatata acgtgcatca aagcctgttc ggtgcccagc tacttctttt
    55081 tctacccaga acccttcttt ttccaattgt ttgattaaag ctgctgagga ataaaattca
    55141 taattactta cttcaggatg gtcgtggata gctagtgcaa gtgcttgata ttctggtaaa
    55201 cggtattgaa tcagatcctt caattgattt gttgagagtg tggttgtcat aaaaatttcc
    55261 tcctatgcta gtcgtttttt cttattttct cccgaatgtt tcccacgcag gtacgcttga
    55321 accttttgat gttttttcga ttactttggc tgtttcttct gtttgatagg catctactat
    55381 tttttgatac gttttattgt cttcatcttc ttttcttgca acgatgatat tgacataagg
    55441 acgtgcatgc tcatcgactg gttctaagaa gattgcatca gaagcgggat taaatccagc
    55501 atctacagct acaccgctat tgatgactga aatatctaca tctgacaaag cacgtgctgt
    55561 ttgggaagca tctaactcag aaatgtctag atttttttta ttctcggtaa tatcagaaac
    55621 ggtaggcgct tggccttttg ccttgtccac tttgatcaat ccagcagttt gcaataacag
    55681 aagagctctg ccgccattcg tgacatcatt agggattgca acttttgctc catctttgat
    55741 atcagccaca tcttttaacg tattggaata aattcccaac ggtgcattaa ccgtattccc
    55801 aatcgatact aaatcagttc cgtgttcttc attgtaattg tctaaaaaga attgatgttg
    55861 gaaggaattc aaatcgatcg atccatctgc taaagccgca tttggctgat tgtaatctgt
    55921 aaatttcaca tattccaaat ggatgttttc ctttttcaaa cggtctttca catcgtccca
    55981 tacatctgta tcttccccaa tgatccctag ttttacggtc gtttcttttt tttcagttgt
    56041 agctgctttt ccttggctgc atcctgccaa ccaaataatt gctacaaatg taatgactgc
    56101 aaaacgaata atttttttca ttttttctcc tccattttca atgtgtgact tttttaatca
    56161 gttgattact gataaattga ctcaaaaaaa ctaagaccag aatcaataat gtagcgacaa
    56221 tcgttacatc tgtttggaat cgattatatc ctctcgatat agcaagattc cctaatcctc
    56281 cggcacctac tgctccagcc atggtagtca gtccgatcac attgatgatc gtcaacgctg
    56341 agacccgaat gataccaggt aacccttcta acaaataaac acgtaaaatg atgccgattg
    56401 ggctcgtgcc catcgcttct gctgcttcga tcaccccagg atcaacttct agcagtgcat
    56461 tctcgatttg acgggcaaaa aacgggacaa cgccaaaaat caaagggact aaagctgctt
    56521 tggcaccaat cgtcgttcca actaagaaac gagtagtcaa agctaaaaga gaaagcaaga
    56581 taatgaaagg gatggaacga atgatattga tcaacttatc aagtatttcg aacagcagcc
    56641 tgttagctag taatccattt ggacgtgtca ctactaacgt cacacctaag atgattccga
    56701 tgatcccacc aatgaatgcc gtccaaaaag acatatatag tgtttgcttt gtcgcttcga
    56761 tgaattcatc cggaatcaaa tagacattcg gcaaatatgt tttaaaaaat tcagtcattt
    56821 tagtttcctc cttcgatgac tttgatacgg ttatctaatt catttttttg taaaatagtt
    56881 acttttacac cagatttaat caaataatcc aatgcttttt gccgctgttt ggtttctcca
    56941 gctaaagtaa cgatcaaact tcctaagggt gtttcttgta atagctctac attaccgtat
    57001 aagatattcg ctgttacttg gtacttgctg taaagatgag cgattagagg ttcgttcgtc
    57061 tggttgccga tataacttaa ttccaccaac catttatttg caatctgatc ggcaaaagca
    57121 gcatgggcac tgattgtttc caatgcttgg tcaaggtgtg tcgctgtccg aataaaatct
    57181 ttagtcaatt cttcttcagg atgactgaaa atctggatgc tgctaccttt ttcaatgatt
    57241 ttccccgctt ccataaccgc taccttgttg cagatttctt tgacaacttg catctcatga
    57301 gtgatcagga cgattgttag acctagctga cgatttagtt tttttaacag tgcaaggatc
    57361 tgaagggtcg ttttcggatc aagtgcacta gttgcttcat cgcataacaa cactttaggt
    57421 tcatttgcca gagctcgtgc gattgccact cgttgttttt gcccccccga cagttgttta
    57481 ggatacgcag atgctttttc ttccagaccg acaagttcca gtagttcatt cactttttga
    57541 cgacgttcct gttttgattt tccagaatac tttagagaaa aatctacgtt gtcaaaaatc
    57601 gttcgacttt ccattagatt gaaatgctga aagatcatac cgatggcctt tctttctttt
    57661 cgcaattctt ttggagagag ctggcttaaa ttcgtctgat tgacgatgac ttctcctgct
    57721 gttggtttct gcaacaaatt catcacgcgg actaacgtac tctttcctgc acctgagtaa
    57781 ccgacgatcc cataaacatc ccctttttca atcgttaaat ctacagaatc tactgcctgt
    57841 atctcttttt ctttttgttt gaaacataca gaaatatctc gcaattcaat cattaacatt
    57901 cctccttgtc tataaaaaaa gcatcctcaa gaaaatgaaa atagtcattt tcttgaggac
    57961 gcctttttgc gtgttaccac ctcatgttca agctgtgttc acacacaact cctcttcaag
    58021 taccatcata ctctagcaag atatcggtcg cagccgtcac cgccttacat ctatgctcgg
    58081 gatgaattgc tcgatggcca ttttccaata gtcgttcctt gcttcttctc agctaccgaa
    58141 gctctctgtc aaaggttctt ctatcgtact taccatttca atgcaaataa tattcaaaaa
    58201 aaaaatcctt ttactaacat aaactatgtc agtaaaagga cgacgtatcg tggtaccacc
    58261 ttttttcgga agtttccttc cctcaagccc aacatctcaa aaagagagat tggcgttcgt
    58321 tttaacggtc gaacatttcc gaatttgcct acttatcgac aaattattct ccaaggccat
    58381 tttcagcttt tcttacttga ctcttcacac cagccagagc ctctctgcaa agtttccaag
    58441 cttactttcc ttctcaacga aatcaatatt ttgttgttgg gaataatcta caggaggaaa
    58501 actgaaaagt caagcatgaa atccaaatta ttttttctat atttattttt ctgttttttt
    58561 atctaacatt tcaataacag ttcgaagatc ttttccttcc gcaagaaggt tcaatttttc
    58621 cttctcttcg acgctataat ttcgaacaaa actggaatcg ggaatcaaaa caacgcctag
    58681 tcctgcacgt gaagcggctg tcgctcctac taaagaatct tccactgcaa aagctgaaag
    58741 agcttctaat cctgttcgtt ccaaagctgt cagataaggg actggtgaag gcttgttctc
    58801 cgatacttca tctccgaacg taaacgtatc aaagtaatcg gctaattgaa agtgatccaa
    58861 gatatctgtt gctcttttcg taacagttgt cgtagcaatc cctagtttca tatgacgttc
    58921 ttttaagtct gtcaatattt cttttgcata gggtttcaat tggatagctc cacttgtcag
    58981 ctgttgataa aaatattctt cacgctttgc tcggacttcc tgcacttttt caggactgcc
    59041 tgctgcctgc actaaaatat caaaactttg tttccatttt tttccgcccc aagcgtcaac
    59101 gatttctttc gggatatgaa tatcaaattg ctggaatccc caaagccaac catcccgata
    59161 cgttctttcc gtatccacta acaaaccatc taaatcaaat attgcacctt tcatctatac
    59221 attaatcctt tccaaaacaa tacacctagt ttagcatgac tgatccaaaa tgaacagaag
    59281 catagagccc agccgcatca cttataagag ttcttggaat cgacggatat agattttctt
    59341 cacagctgtc acaagcgcca gataagcgac gactgttata aaaaaccata accagtaatt
    59401 gccagggagc ggcatcaagc ctaactcagc accaaatcct gtgaatggaa ggactgaacc
    59461 gacaatgatt cctaatgtag tgataaccag catggcaaat gttgcattgc tttggataaa
    59521 tggtattttc ggtgtacgca atgcatggag tactaatgtt tgtgtccaca gggattcgac
    59581 aaaccatcct gcatggaata atgcgataaa aatcacttgt tgtgagctat ccaatgtatg
    59641 gaaacttcca ccaactacag caggacaaat aacaaaatac atcaacaagt aagtagtgat
    59701 atcaaaaatc gaacttgttg gaccaaaata aaccatgaat tttccaatac tagatgcatt
    59761 ccatttcttt ggctcatcca aatattcttt atccatccga tcccatggta aggaaatgca
    59821 agaaacgtca tagatcagat tcaaaaatag aagttgcaaa ggcaacattg gtaaaaatgg
    59881 taagaacgta ctggcaatca gtacggaaaa catattgcca aaattagaac ttgctgttgc
    59941 cttgatatat ttcatgatgt ttccaaaagt ttctcttcca gaaagaaggc ctctttccaa
    60001 aatcgtcaaa tctttttcta aaaggatcac gtctgctgat tcttttgcga tatccacagc
    60061 tgtatccacg gaaataccga tatcagccac tttcattgct ggagcatcat tgataccatc
    60121 tcctaaaaat ccgacagtat gcccattttt acgtaaagct gtcgtcaatc gtgctttttg
    60181 ctgaggattc aattttacga atacttcgtg ttcttcagct acttgcgcta attcatgatc
    60241 attcatttcc gagattttct caccagtaat caattcattg atttctaggc ctacttgacg
    60301 gcacacagac cgtgtgacta attcattgtc cccagtcaga acttttacag ctacaccatg
    60361 ttcttttaaa gctttcaacg cttgttttgt tgtttctttt ggtggatcaa ggaaagcaag
    60421 ataaccaatc agaaccatgt ctgactcatc tttgactgaa aattctccaa caacgcttgg
    60481 attggtcttt tgtgcgacac caatcactcg taagccgtct tcattaagtg attgtacttt
    60541 tgcaagcacc gcttcttttc gttcttttgt taatggtgcg acagtaccac caagatcaat
    60601 aaatttagaa atgttcaaca tttcttcaat cgcgcctttt gtgatcatct gtgttttgcc
    60661 agccggatca gcgactacaa cactcatacg gcgacgttca aaatcaaaag gaatttcatc
    60721 tactttttga taattgattg tatctgtatc taaagtttct gctgcttcat caatgatagc
    60781 cacatctaac aaatttttca gccctgtttg atagtagctg tttagataag catggcgcaa
    60841 aacacgatca tcttcatttc cttcacaatc catatgatat tcaagaatga ttttgtcttg
    60901 tgtcaatgtt cccgttttat ccgtacataa cacatcgatc gcaccaaaat tctggatagc
    60961 atttaaattt ttgatgactg ttcctttttt ggccatcaca cttgctcctt tgaccaaatt
    61021 cgtcgtaacg atcattggaa gcatttcagg cgttaaacca actgccacag ataatccaaa
    61081 aagaaaagct tctaaccaat ctccttttgt aagcccattg ataacgataa ctgctggagc
    61141 catcaatgac ataaatttga tcagcagcat ggatgttttg tggatgccta attcaaaact
    61201 tgattggatg ggtttttcag atagcgtttc tgctacatgc ccaaatagtg tgtcatttcc
    61261 gacagaaaca atgattcctt ccgcgcttcc actgatgaca ttgcttccca taaagacaag
    61321 attttcataa cttgtttcac tttgctgatc gtcttcacat actttcgcat gcttttctac
    61381 tggatagctt tcccctgtca atgctgcttg agaaatgaat agatcctttg cggacaataa
    61441 acgcatatcc gctggtatca tatctcctgc tgaaagccga acaagatctc cacagacgat
    61501 ttcttccata ggaatctctg tatactcgcc atttcgtttg acagctgccg ttactttcac
    61561 aagtgatttc agtttttcag ctgcttgatt agaacgcaca gactggatca acgtcatcgt
    61621 cccactgacg ataaccatag tgaagataat ggctacacca aagagatctt tatctcctgg
    61681 agcggctaat acgtattccg taatgaatga aataattcct aatgcaatca acactaatgt
    61741 aaagggtgtg atgtatgctt tcaatatttc tataatgaat ggtgtttttt tgccatatga
    61801 aatcgcattt tcaccataag tttctcttga acgctcgatt tgttcttctg acaatccatt
    61861 tggtgatgca tggaacaatt caaataattc ttgcttcgtt tttccagcaa aagctgcata
    61921 gattttttgt gtatctttct ttttttccat ctcgatctct cctttgtgtc caaaagacag
    61981 ctgttctcgc tgtttttggt cttttgctat tcatcggatc gatagagaaa atgctgaaag
    62041 gggctgagaa cagatagata atagccctgg cctttcctct aaatccttgt ttttcgaatg
    62101 actgtcatcc atttgttctc atctccttta ctaagtaatt ttaattcatg acttccaatc
    62161 atttttcgaa tagttatttt cccaactcgc tcacctccct ttttgttttt tcacctatgg
    62221 gatttgcggc aacaaaaaaa cctctcgcca aatactcagc gaaaggtttg aaaaagcaaa
    62281 tcaaaaaaag cttctcagat ctcatcgttg agttttgaca ctgtacaacg taaaaagcag
    62341 atatctgctt ttagctacct tatgaaaagc cttatctcga caattcctgt tctacccatt
    62401 ggcgtctctc gacgtttttg ggcagtagcc tatgtttgta taggagcctc acctaacaaa
    62461 tcctattcgg ttttccctcg ttaatataac aactaaaaaa gaggatgtca aatcaatttt
    62521 ccatgttttt catacttttt taaaatacac gcgttatatt tcctgtctca cgcagtttta
    62581 tttgtctcat tttccacctc ccgctataat agaattatag taggaaacga ggtgctgtta
    62641 tggaacgaac acttgttatt atcaagccag acggcgtaag acgccatttg gtcggaagca
    62701 tcatccaacg ttttgaagca aagggactgg ccattgctga aatgaaattt gcaacgatga
    62761 cacctgaact agcaaaagaa cattatcagc acttgactga acgtagtttt tttgatgagc
    62821 ttatcgatta catgacttct ggtccggtcg tttatcttgt gctggtcggc gaggaagtga
    62881 tcgatatcgt ccgtaagatg gtcggagcaa caaaaggggc ggatgccgtt ccaggtacga
    62941 tccgaggaga ttatgcactg ccggggactg aaaacatcat ccatgcttct gattcccgtg
    63001 atgctgcaac aaaagagatc gcccgctttt tcccgccatt cgatacaaac aaaccgtctg
    63061 aaaaagcggc gaagtgatac aaatcctaaa ctgttggtct aactgctggg tttagcaatg
    63121 gccagcagtt ttttctctaa agaattcctt tgattcttcc ctaatgtata ttcgatcact
    63181 gcgaaaaact cttggtgatt ttccgatttt tcttccccta aagcagcaga aatcagtcgt
    63241 tggtaataat ccgccatcaa tgtttcataa atcactgtac ttctttcttt atgcgctaaa
    63301 ctccgtttca tatcttcatt cacgctacgt gcctttttta agcgaccatt ttctatataa
    63361 aacaaagtca agttcgtcaa aaaagtaaag agatactgct cgtgattatt cagttgcgcg
    63421 atccgtcgca ttcttttttt gattttcaaa taattattct caataaaacg atcactgaat
    63481 atccaaggaa aatctgctag aatagatact tcaaattgcc catactctgg tacttgcatc
    63541 aaatattctt caatgatacg acattcataa cgcaaaaatt caaattccgt ctcagatact
    63601 tctgtttttt tggacatgtg cagattcaaa accaaatagt acagatcttc tgttttctta
    63661 tagtgcctgc ggttattagc aatttctttg taaggatcaa agctgtcttc ttgaatccga
    63721 tctagcattc gtcttttttt ctttaatttt tttggctcat caagctgatt tcgtatccat
    63781 tcatattcgg caagtgtcat gttcattcgc tctaaaaatg atttcaatgt tccaaacgat
    63841 acttttttca ctgaatttgt ctcgatcccg actagcgaag ttttagaaca gattccttcc
    63901 gctaattggg tctgtgtcag ctttttgttg actcgaagct tcttaatcaa ttctccatca
    63961 tacataatag ttctcctttt ttaattgaaa ttaacccttg gcttttccag aatgcttgcc
    64021 aataagagga atgattattt caatttaaat tttccgcatt caataaatag atacgttaaa
    64081 aataaaaaat acacgaaaaa aataaaaaaa tgtttttctc ataaaaaata ccaaccttca
    64141 agcatgagac tgctgtctaa tccctgaagg ttggtttgat tgtttattga tcattttttt
    64201 actgctccgc attggttcct gttactggat ataggatagt cgttgtttta ttgccgtttt
    64261 ttgaaaagac actggtcgaa tgttcacctt tttgcttttc gattgcttca ttacgttccg
    64321 cttcgttttt atagtcatat tttttcggat caatcgtctc aaatccgttt ggcacataaa
    64381 accgcaagag attttcctga ttcagcttat ctgaaagact taacgcagtc ttgacttttt
    64441 cctgatcttt ggagatttcc tcgtcgattc ctgctgcttt cgtatcgatg atttctcctg
    64501 tctgattatt gtaagctttt cctcctagga cggtgtattt gggcgtcacg aagttcccat
    64561 ttcgaaaagc aactacttga tcgtgctgag aagataataa gtctgtacca aaatgaagat
    64621 aatctttatc atcgattccc aatagatgta gtaatgtcgg caaaacatcg atttctccac
    64681 catattcatg attgactgtc cctttagtgt aaccaggcat atggatcatc aatggcactc
    64741 gttgcatctg tgcgttgtca aattcatccc atgtatctgg atctttacca agagcacttg
    64801 ctaaatcttt attatctgta ttcgagatcc caaaatgatc cccgtaaatc acaaagattg
    64861 aattttggta aataccagat tttttcaaat acgtaaaaaa ttgttccaat gattgatcca
    64921 gataatgggc cgttcgaaca taattatcta ctgtgctatt gccagtattc aaagatggaa
    64981 agtcgaaatt cttgtcatcc gtataataag gcgtgtggtt ggttacggaa agaaatttcg
    65041 tgtaaaacgg ctgttgtaga tgttcaagat attgggcaga ttctctgaat aaatctttat
    65101 ctaatatccc ataacctaac gtttcatcgg attcatcaaa ataagatcga tcaaagaaat
    65161 tgtcataccc taaattttta tatacatgat ctctattcca gaaactagct acattcccat
    65221 ggaaaacagc acttgtatag ccttctgttt gaccaagggt cgctggtgct gcttgaaaga
    65281 cattatctga cccaagttct gtgaataatg agccttgagg taaaccaaat gtgccagttt
    65341 ccaacatgtt ttcagcatca cttgtctttc cctgtcctac ttcatgaaag aaattgtcaa
    65401 aactgatcgt tgcttgattc tggaaaatac tatttaaaaa cggcgtgact tcttgtccgt
    65461 ctaccttcat attgatcaaa aactgttgaa aactttctaa atgaaggaca atcacatttt
    65521 ttcctttagc aatcccaaat gtttcaggat ttggctctgc ataatgtttc tttgtatagt
    65581 ctaaaacttc atcaattcca ttactgcttg catgcgcgcg aacactgcta gtcattcctg
    65641 ttttgattcc gtcataaata gtgtacgcat cgattcctag atatttgaca atataggaac
    65701 ggtcaaatgt ccgctgtagc aattggggac ggttggcttc gctcaacgct aaatttcctg
    65761 aaaaaatcaa tcctgaaaga caggtaacag cgatagccat cggtttgctg acagggttgc
    65821 ttttgatagg tattttcttg accttcaacc aaaccagtag cccaatgaac acagcgatat
    65881 ccaaccaata gatgacatca tggggtttca tcaaagaaaa ggagcttcct gacaaccctt
    65941 gtgacacttt cgaaaagcct aatacagatt tgactgtaat gaaatctgtg aattcccgat
    66001 aaaaaataat attcaagtac aacaaaagcg tatttaaaat atcaatgatc aaaagaatgg
    66061 ctaacgctgg ctttggcttt ttaatataca aagaaaggcc aaaaaacaat aaggtagtcg
    66121 caatcgggtt gatccacaag ataaagtact ggatcgtacc ttccacacct aatgaaaaat
    66181 ctgcatagta ggcaatgatc gtcttcagcc agaaaaagaa aacagctgtc aaaacgattg
    66241 ctaaacgatt ttggcacaat tttttaagtt gtgtcacgta tatcacttct ctctattcac
    66301 attttttctt attttgctcc tgaaaaatga aaatttccta aaaaagttgt tatcttaaga
    66361 tttttttatt ctttctaaag attattccat tcatttttca cagcataaaa tcgtttcggt
    66421 gtaagcggtt aaaatagtaa ggagataaaa atcttgtggt gaccgattta ctctatagta
    66481 ttcaaaagta gtttctcggt attcgtacaa aaaaaacata ctaagattag aggggaacat
    66541 cattgacgaa tgatgttctc ctctattttc tatttttaga ttatagtgaa gagtgaaaga
    66601 aagttcgaac aaagccttga ggactacgag tccctatcaa aaaccgaact tctttactgt
    66661 cattttagaa tcaggtttac gtatgttggg gccatgagcc cgtgtatagg aaattggaat
    66721 cgaaatgaag cagtaaagtt ctttcaacac ttaaaaagga ggaaaacaaa tgccttacat
    66781 tcttgcatta gatgtttcaa tgggacacag ctacagtgtc ctatacaaag acgacacctg
    66841 cttatttgaa gacgagatcg aacacactca aagaggattt catgcattac tcgaagagat
    66901 ccagcacttg cctgaacgtc cattgattgt ttttgaagca acgggtattt attccagacc
    66961 agtcgaaaag ttctttcaag atcatcactt ttcttactgt ttgttaaacc cgttagaagc
    67021 gaaaaaacag atggaagaaa acaccttacg cagttggaaa acagataaat cggatgccca
    67081 tcggctcgca cagactcatc ttaaaaatca acgtcaacca aaagaagtac aaagcaattt
    67141 ttacttagag atgcgcgatt tagcccgttt ttatcaagaa attgagaaga aaatcactcg
    67201 actgcgcatg gatttacaca actgccttca gttgactttt ccagagcttg aacagttctt
    67261 ttcaaacagg ctgacccctt acgcattgac attgatccgt ctttttcccc atccagattt
    67321 tgtattggca tctactcgga caaaaataaa aaataaactg atcaacgaaa cacgggaaaa
    67381 aatctccgcg aatcgtgccg agcaaaaggc agatcaaatc atccactatg cacagtgtgc
    67441 ctatccagct gttgaaaaag acagtattca ctgtcaaaaa acgatctatt acgccgaact
    67501 tctccaagat ttactcgaac aaaaaaaagc actggcgaca caaatgatca aaaaagccga
    67561 agcctctcct tgctttttgt tgtaccaaac gttccctggg attggcgcac tcacagccgc
    67621 tttattgctc ggtgaattag gagatatcac acgatttaaa acccataaac aattgaatgc
    67681 ctttgtcgga atcgacatcc gacggtatca ttcaggtaag tatactggcc aagaccgcat
    67741 caataagcgt ggtaatccca aagcacggaa aattattttc ttcaccattc gaaatatgat
    67801 tcgccagcaa cgcgcagctc ctaatcatat tgtcgattat tactacaaat taaaaaagca
    67861 acctatccct aagaaagata aggttgccac agttgcttgt atgaacaagc ttctgaaatg
    67921 tatgcacgct atggttaggg cacatacaga gtacgactat gcgtacgcgg tctcagtgga
    67981 ccattaacta aaccacttac agtataccac ttctttgccc agatcgaaaa ttttttacga
    68041 acggggcttt atttagtgtg ccttgatttt gtcgctttcg tttacgagct atttttcttg
    68101 caccttttac ttgactaatc gtaggaaaga ggctgtgaca aaattcttgt cgcagctccc
    68161 tatttcttga tgcaggacag ctttttcaca acctctccac taaacggtgt tcaatcagct
    68221 gaccttcggt attagctcaa aaaacggcaa aatatgagga gctattttcc cgtttttttc
    68281 tctaatactc aggtcaaacc gctgatttca caacctctga ttcacggtgt tccagaagta
    68341 gcttcttcgg aaataagccg aaattttaca aaaacttgag aagcactttt cgtaaatttc
    68401 ttcttatttc ttgaagctga ccacttctgt cacaacttct gtttttcatt gtccataggt
    68461 ttgatattgt ccttctgatg actcattcgt aatgattgag gcttgatttt cttcatttcc
    68521 cgttatcgtt tgtccactgc cagaatctga agggcttagt tctgtcgact cgtttttttg
    68581 agaagaagca gttgttttct tgacttgttc gttggtcttt ttccattccg ctagtcgatc
    68641 ggccaccact tttttgtcca ctttttcaga ataagctgta accacttttc catttttcaa
    68701 acgtgctacc ttgtcgccat catgagtcaa aagcaaaacg accaaatgtt tgtctttgaa
    68761 ttgatattgt ctgagagaaa tcgcactaag tacgtcatcg atattgataa attgattttc
    68821 ttcttttcct tttggcaaat agatgtccaa ttcacctttt tcgtaattgg cagttaattt
    68881 atattcctcc caccaataag ttgagaattc ttttttgaaa ttatctactg attctttgct
    68941 tgctacgatt ttttctgttt ctttctgagc aagatctgct gtcatttttc ctgaaaatgc
    69001 tgcggataaa ataagcagta agaaaaaacc gaataaccaa aagagaagaa acggtctttt
    69061 tttcctcatg ccttcctcca ctcctattta attttgacta ttctattata tacaaaaaat
    69121 gaaatagaaa gacaaaaaag ttgaaaaaga tcgtaaataa ttgaacttct ttttcctgaa
    69181 gcggtaagaa cgggaatttt catacattct ctcttggcta ttctttaagc ttcaaatcca
    69241 tttctgtctg atacatcttt gaaccaatga cccgatttct tgatcgttct ttttccatct
    69301 tgtgctaaat ctactgaaat aaaaccgtaa cgattcttat aggcattggt ccacgaccag
    69361 ttatccatgc atgtccacat atgataacct aaacaattgg caccttcttg aatggcttga
    69421 tggacatatt tcagatgaga ttgaacaaat tcgatccgat aatcatcgtg gatcatacca
    69481 tcttccttga taaatcgtgc ttcattttct acacccatgc cgttttcaga aataaaacag
    69541 tcgatattcc cataatgatc tcgtacattg atcaaaatat catagattcc tttttcatag
    69601 atctcccatc cgcgataagg attcatttta cgaccaggca tttcataatt gtcgaagtaa
    69661 tcctcaggca taggaccgtt tttagtatcg attggtgttt cttttgcttt tattcggcgt
    69721 ggttggtaat aattaattcc caaaagatct actgtgtttt ctttaatgat cgtcaaatca
    69781 tctggatgaa tctccggcat tagatcgagt tcttttattc tctcaatcaa ttcactggga
    69841 aactcgcctt ttacagctgg atcaaggaat gaacgattga agaacgcatc tgctattcgt
    69901 gctgctttaa catcttcggg atttgattcg tctcttggat aactcggtgt caaatttaag
    69961 atgattccga tcacaccgct ttgatccatt tcatggtaag ctttgatggc taatgctgaa
    70021 gccaacgctt catgataacc aacttggatt gcctttttca tatctgattc ttccggataa
    70081 tgccatcgat acaaatagcc tgcctcgact ggaacgattg gttcattatg ggtaaaccat
    70141 ttttttactt tcgagccaaa caattgaaaa caactttttg cgtatttttc ataggcttca
    70201 accgtttctc ggttcaacca tccgcctttt tcttgcagat acatcggcat atcgaaatga
    70261 tacagattaa caaagggttc gataccgttt tcaatcaact catcaaaata gtgatgatag
    70321 aaacgaacgg cttcttcgtt gattgttcca gattcatcag gtatcaaacg gctccattgg
    70381 atagaggttc gaaatgaatt atgcccagtc tgtttcatca actgtacatc ctcttgatac
    70441 ttcgtataaa cttgcgaggt tttttcaggt cctacttgat caaagaactt ttgcggttcg
    70501 tttttgtacc aataatcaaa aatattctct ccttttccat cgcctgaaat tcttccttct
    70561 gtttgtggac cacttgctgc agagccccac caaaaatttt ttggaaattg atatcttttc
    70621 atcaaagcac ctctttttct tttttagttg attccatgta tgatattttc catcacaatc
    70681 actttttcat tttcttcctc ttcttttttg attcgtttca acagctgttc tgctgctcgt
    70741 tccccgattt tatctgttgg tggcgtgatc gtgatttttg gaaggatact cagatcgttt
    70801 ttatctaaat aatcatagtg actgaacgca atatccttcc cgattctgac accttcttga
    70861 ttgaaacatt cgatggcacc aatcgacatg ttgtaattgc tgacaaaaat agcagttgcc
    70921 cctttttcta ataatgcttt tgccccgtaa tagccgcttt ttctagaata gtctcctgta
    70981 aagatctcta aatggataga cggatccttt tgtaccgctt ctttggctcc agctaaacgt
    71041 tctcttgcta cgtaatctgt ttgagcggca gcaataaatc ctattgtttt atgtccttgt
    71101 ccgccatgat gagcaatcac ttttgctaca ctttctcgat cattcactac tattgtatca
    71161 atacctgctg gcccacccgg acaattcaat gcgacaactg ggatactcat ttttgtcagc
    71221 atttcaaatc cagaccactc ttcttctgat aagaagacga tcaatccatc gatcgcatgc
    71281 ttcatcaggt attcgatttt ttgttcgatt ttttctggct gatcggcaaa cccgcttaat
    71341 aataagctat acccattttc ttcagctact ctttcgatcc ctgaaacaac ctccgaacca
    71401 aatcggttag atatcccgtt tatcaacagt ccaatagaga aacttcgatt attcttcaat
    71461 cctttagcaa tgatgttttc tttatagtcc aacgctgaaa tcgcttctga tattttttcc
    71521 atattctttt ccttcagctg ctgaccgttt aaatagcggg aaactgttcc cactgaaaca
    71581 ccagccatct tagccacgtc acggatcgat gccatacatt ttcactcctg ccagttacat
    71641 ttgatttctt tttcttgttg ttcgaccatg atgaccgctt tctttgcata atgccgcttg
    71701 tcatcaatat ccatataact aaagtcttca gaagtgagtt caaaaacaag cagtctttcc
    71761 tcttgagacc gcaattcatc tttacgaaaa gctttcaata atttcgttct ttggatgaca
    71821 acgccgtcaa ttaatcggac atagacaaga gtacttgttt tacctgaaac acttcctgta
    71881 tttttaactt taattgatat tattactttg tcaatatccg ttttgacttc catctgactg
    71941 tattcaaatg ttgtatagct tagaccatgt ccaaaaggat aaaatggact tccgcttaaa
    72001 tcataataat tctcttgttt agaagcagca cgctgatagt aataaacagg tagttgccga
    72061 ctatttctag gataagacaa actcaatcgt ccgcttgggt tatttcttcc agaaatcatc
    72121 tgcgcaatgg cttttccacc ctcctgtcca ggaaaccatg ctgttgcaat ggcattcgta
    72181 aatgactcga ttttcatcaa atcgtagggt cttccttgca caagtatcgt gatgattggc
    72241 ttgcctagtt gatacaattg ttcaatcagc tgttcttggt atccacctaa agaaagagaa
    72301 gcaacatcta cattttctcc agaatccatg ttgatccctt tcgatgaaac tgccccgtta
    72361 cgaagaaatt ccatatcaaa gttccgcgca cttgatccac ctagaactgc aatgatcaca
    72421 tctgagtttt gagcaagggt caccgcttct aataattttt cttcctgatc ctcctgattt
    72481 cttacttcac atccttgtgc ataagaaacc tttgattggg gaaactctgt ttttatctct
    72541 tgtactatct tttttttcaa acggtcttct gtttgtggtg cagagtagtc tcccaacaag
    72601 tggtaaacat cgtgagcatt tggacctata acagcaatgt tttttacttg ttgatccaac
    72661 ggcaatatac cgtcattttt tagtaaagtg atactttctt ttgctgtctc taaatttaag
    72721 tgctctgatt cctccatgag atgatcccaa tactcctttg gatcgtttgc aaatggctgt
    72781 tcaaataaac ctaataaaaa tttgacagat aaaactcggc gaactgcttg atctagtagc
    72841 ttttcatcta cgacttgatt atcaatggct tctgcaatct tggtataggt ctcatcccac
    72901 aaactgagat cgattcctgc cgctaatgca tatgctgcag cagtcttttt atctgtaaaa
    72961 acatcggata aacgatccaa agccacaccg tctgccataa cgattccttg ataaccgatc
    73021 tcttttctta atgtttgctc aaaaagcgct cgattgatat gacaaggtat cccgtcgatg
    73081 tcattataag cagccatgac acctactgca tttcttgtac tcttcaataa tggtccgtaa
    73141 atatcggaga actctctgcg tccaatcgtt actgtgcctg aattatgacc gcctaaagct
    73201 tctccttgtg cgatacagtg ctttaacaca acaccgatct gatccttctt cttattgatt
    73261 tcctctactg tctgatcaag aaaagaaact ttttctgaaa taatctctcc ttggaaccct
    73321 cgaacgaccg cttcagaaaa acgagctgag agaatcggat cttccccaaa gcactcttct
    73381 gtccttcccc aacgaggatc ttttgccaga tccaaagtcg acaccagcgc taaatgaaca
    73441 cctttagcag ccagttcttt tgccatcaat cgactcgatt gttctaataa tgctacattg
    73501 aaagtatttc cacggccgat attcgttgga taagaaatcc catccaagcc ttgatgacca
    73561 tgtggacatt cttctacaag caaaactgga attttccatc gcgaatgctg tagtacatat
    73621 tcttggacta ggttagccac cttccagctt tcttttgcag gaatcccatt cttataatct
    73681 gttttagacc acggatcaga gcgaaacaga ccgtataagg cacccagacc gcctccccat
    73741 ttaacatgtt cttttaactt ttctgttaat tcgatcttgt ctccgttttt ttcataacat
    73801 tcccaaccat acaaatgctg gtttacctgt cctacttttt cagcaatatt catcctcgaa
    73861 agtaaatctt ctactctttg gcggatggtt aactttgggt tttgatacgg gtaatcgtac
    73921 accttaatat cctccttctg ccaattttgc cttattagcg gctaatacaa atggcaggaa
    73981 taaaaataca tctagaatga taagtattac tgttaagact gctgctcgta tatcgcctcc
    74041 tgtagcaata aaagattgta taaccggtgg agtgatccaa ggtgcagcag caactgtttt
    74101 actgatgatt ccaagacttg tggctgcgta ggcaataacc aagttaatag atggtataat
    74161 agcgcatgga atcatatata ttggattcat gactactggt aatccaaaca taattggttc
    74221 cgtaatatta aataaacaag tagtcagacc aaatttagcg attgatcgct gttcttgacg
    74281 tttagaagcc cacaagatag caataactaa cggtaaaata cacccgccac ctccgatcaa
    74341 tccaaatgca ttggtaaagg gctccgtaat aatattagga atttcttttc ctactgaaaa
    74401 agcatccatg ttttcctgaa tagactgtaa caaaggtgct tgccgtatag gagccaaaat
    74461 actcgaacca tgcataccaa acacccataa gaaatcagag aaaaactgta aaaataagat
    74521 gcctgggacg gataaaacaa aagctttcaa tggtgtctga atcgctaatt caattaattg
    74581 cggaacattc aaaccagtcg tatggtttaa agtaaaaacg acaactgaaa aaaataaaat
    74641 gacaactatt tctggtacta aagaattaaa tgacgcagct actgccggtg gaactccttc
    74701 tggcatcctg attttaaaac tcttcatttt cgctaatttg ataaataatt ctgtactgac
    74761 aagggcagca atcatcgccg ttgctaagcc agacgaagaa gtcagacttt gtaagaaaac
    74821 ccctgtagct tctgctgtat ttccgtccat caaagtgact gtacttgata aagacatcaa
    74881 aataaacatt acggctgtac ttagaattcc tgcatgaaca ggactaaatg atggatcatc
    74941 aatcacgcct gtttggatat agtgggttgc caaattccag ccgatattgt aacacacgat
    75001 aatagctaaa atactcatcg taccattatt cacgattgaa gcaagttcag ccaatggact
    75061 tagatcaagt attctttgga ctgttgcatt tgaaaaaatc agagcattca gcaaaaccat
    75121 gacagaagca gccattacta acggcatagt aacgataaaa ctgtctcgaa tggccagcaa
    75181 gtgtcgctgg ctactcatct tagatacgat tggtagcatt ttttcagata gtctgtctac
    75241 gactttcatt atttcatctc ctagattcta aaattgaacc ggttcatttt taatatagca
    75301 ctttttttaa agattgcaac acattttttt aaaacgcttt ctaaaggtgg tggatttttt
    75361 atgacttttg aaaaattatt ctatttaatg gtattttgtg aattttttct cttccatccg
    75421 tttgaagttt tactttccaa tggtataatt tctttatcct atcaaatggg ggaagtattt
    75481 tgaagaaatt aatcgtacta tttattttgt ctgcgggact tttgacattg actggctgtg
    75541 atttgtttgg cggctctgac caatcctcgg acgaaacaac cgattcttct gtcttaaaag
    75601 cggaaaaagc agatatcacc aacagtgtat atacgctaaa agtacgtaaa gatatggatt
    75661 tatccgcggg acagttgaca tttacagata aaaaaatgga atggacacgc acgtatcaga
    75721 cacaaggagc tgattcttct gaatcatctg aagaaaaaac agtgctgaca gatatcaaga
    75781 ttactaccaa agatgacgaa tatattattt caggaaaaga aaataaaaaa gaagcaacag
    75841 tcacatttac caaaatcggt aattaccgtt tgaaggataa ggatggcaac atctacagtc
    75901 tatagtgcca tctgttggat cttcttttgt ttctcccctt cttttctgct atagtaaaga
    75961 agcaagatga ctgtaaagga gacgaaatgg atgatcgata gtcctgatta ttgtacatgt
    76021 aataacaaca aaaatatcca tacagaattt aatgatcaag gaagtttgag tatatgcgac
    76081 aattgccaca aactagtcaa agattctttt aaatcgtttg aatcttatcc tgtcaaaaat
    76141 tatgtaaaaa gcaaaagaag ataagcaaaa tcaagcaaaa ctcactatgg ctgattttta
    76201 tgaacttcaa actcagcttc ttcctttgat caagcttcaa aaactggaat cagtaaaaca
    76261 aacagtggat catttcagtt cacaaatcaa agagtaacgt tttatttatt tcacatcttt
    76321 gaatataaaa taaccaaacg atagaaagac ttattctaca tcacgtagta atttttcttt
    76381 cccgtcgttt ggttttttac ttttagccta attcttgacc tttcgcatgc tgattatctg
    76441 taaaatattt tccagcaggc tttccttcca attcagctaa tttttcttgg atctgacgaa
    76501 tcaccttttt tgcatcttct ggattttcta caaaatcgaa tgtatcccca tccacttgta
    76561 ttttaggaca tacatcaaaa tcctcatacc attgattata gcgggtgttc agtgtttcgt
    76621 aataggtgta taacgtttca tcgctttcta gctgttcata gtcacgcccg cgttttttga
    76681 tacgttctag catcgtgtcc aaagaaactt tgatatggac catcaaatca ggacgttttt
    76741 ttggagcaac atcatctaac tcgtttagca tcgtatctaa taagctatcg tactgctgta
    76801 cttcgatatc cgttacccga cctaaatcag catttagatg gaacaacaga ctatcttcgt
    76861 agatggagcg gtctagcaca ttgtcatcgt tcactaaagc atttttcatt gctaaaaatc
    76921 gcttattcaa aaagaagatt tgcaataaaa atgcgtactg ctcaggattt gaataaaaaa
    76981 gcggcaatac ttcgttatct tcgacatttt cataaaatgg tttagaatca atctcttttg
    77041 caagcatatc cgtcaaactg ctcttacctg caccaatcgt tcctgaaatc aaaatcactg
    77101 acatacaacc cttcctcttc tataagtact cgcctacgta agtttcaaca ggcaattttt
    77161 caaaatcata ttcacgtaca gcttggtctg attttaaata cgtgtgaaga ctttgtgtaa
    77221 tcatcaagtt cgtaggtacc gtctcttctt gtacgatgat catcggtttt ttcaacatag
    77281 ttgccacacc taattcgtaa gccgttcctg gatcgattgt ttgatgctca aagtcaagga
    77341 tagccaaaac aaattctgca tttgtcaact cttccatatc tttttcgtat acttcctgcg
    77401 cccatccagc gctgaatagt tcataattgc tttcttggtg atgacgtgga gagtagaaac
    77461 ttgtgattgt tttgttttcc tccaacgctt tttcgatacg acttactcga tcgatttgct
    77521 cctctgaaaa aaatggtcct gctaaatata tttgactcat tattttgcct ccttcaataa
    77581 taactgattt ttaatagata ctgctcgtaa ttcattgacc agttccaatg gattgttgga
    77641 aaagatcact tgatccaacc attttttatc cataaaatcc tcttttgcaa aagtttctaa
    77701 taattgttgc aagccgctgt aataaccgcc aatattcaat attccgattg gcttatcagg
    77761 tgtcaggccg atcgctatcc aagaaagaag ttgcgaaaat tcctccaatg tacctagacc
    77821 tccagggaaa acgaggacag catctccttt ttcaaataat aatacctttc tttcatcaat
    77881 tgtctctgta ggaataaatg tagtaacatc tttcccaggc agctcagttt caaaaaggcc
    77941 atttggatag atacctgtga cttttccgtt attttccagt actgttttac taatcactcc
    78001 cataatcccg gagtatgaac caccgtaaac cagttcgatt tcttcttgtg ccatatattt
    78061 tcctaacgtt tgcgcaataa atttgtaact ttctttattg ccaaaacggg aaccgcaaaa
    78121 aacagtaagt ttcataaaaa aacactccct aactcaaaag tctatcttca ttctacacgt
    78181 gtttttttaa aataaaagac tagattttgt agttttttag tggtatatag atcaaacacc
    78241 actatatata gtatttgcaa aaaaataatt tttcagctat tttacagtaa ccaaaaaaat
    78301 aaataactag taaatataaa attgaaacga cttacttata gaagaaattg ggatttcgtc
    78361 ctgcatgtca ataacacgca ttatttaaat agtcacacac ttgtttctcc tattaatgaa
    78421 aaatccattt tattctcgtg ttatgtttca ccaacgcctg atgtttctct aaataaaaaa
    78481 gccgacgaac caaataatcg aaatttgatc attttggttc atcagcttgt tcccaaacct
    78541 ttgtattaac gataaatagc tggattcgta aaactatcac ttggatcatc actgctggaa
    78601 gaaaattcgg tgataaccgc gcctgttgca cctgcctgga accagtgttt aatattttgt
    78661 tcgatcgtgt actgatctcc agcgtgaagt atgatttctt tttttgccgt atagtaacgt
    78721 tcttgcccct ttggaataat acaggaaagt ttttttgttt cttttccttc gacataaaga
    78781 tatactaagc cttttcgaca acgaaaggtt tccttttttc cttcattctc atctcgaggt
    78841 gggtgccgat gctctggaca agtttgataa ggcaataata ccagttcttt cccacagtat
    78901 cgctcattat tttcataaac aaataaattc aatccttcag tctcgattgc tcctaatcca
    78961 aaatctgtat attcgattct ttctaattct gtttctttca atactactcc tgaatctagg
    79021 aacatttgtt gtactctttt cttgtaatcc attctgttcc tcctaactga ttgtcaagtc
    79081 atcccaagat atctcttctt cctctttttc ttcttggatg acttctgcat ttgggtcaac
    79141 tggttttttc aataataaaa tagttattcc cgtagcaaaa gaaccagcta acaatgcacc
    79201 aatgaatgcc catggtctgg tcatcgtagc gactgcaaac attcccgatg ccggaatacg
    79261 gctatctgcg ccccaaaaca tgctcaatcc accgccgact gccccaccga ctcccgttgc
    79321 tatgacattg cgtgccaagt cgttcaatac gatagggata catccctctg tgatctgaca
    79381 gatccccata ggaaaagcgg tcttcaatgt atcgatttct tgacgattga atatattttt
    79441 acgaatgatt ttccctaaga aataagcgat cgtcaagccg aatggggtta ccatcgaagc
    79501 taaaatcaat acagtgattg gttcatagat tccttctgaa aatcgtgcca caccccctta
    79561 tccagaataa atggtaatcc agaaacagcc gggtatctgc ggtaataagc ctaaccaaac
    79621 gaaaaatatg agaagctaat atgagaagct atttttgttt ggctgttctt attacttgat
    79681 gcagggcagc tttttcacaa cctctttttt tatttatgtt tcataatcaa tatggtaagg
    79741 atgcagctcc gtatggtaga ccgcctccga atattcaatc atttccccaa tttgcgtaga
    79801 cgatttccgt atccgtttga tgccgatctg tgcgtctgtt ttcagaattt cttgttcttc
    79861 ttctgttaaa aatactgccg agaaatcatc agaaaatgag tcaatagtat atcctttttt
    79921 cgtcagcaaa cgatacaaag attctttgcc aaattcttct ctgctgaatt gcatcatttc
    79981 ttgtggaaga taatgaacaa aataaatata aggctgattg ttcaaataat ataagcgctt
    80041 aaaacaaaca gcttgctcac cgaaaaagga aaacaaagga tcttccttct ttatatggac
    80101 caattgcaaa tccagcgttt ctttccggac ttcatatcgg gagttctcca agatttgcgt
    80161 aaagcttgcc gctttggata atcgattgta aggacgattg cttagaaccg tcgtcccacg
    80221 accacttttc tttgcgacat attcatctga tgccagcagt tcgattgcct ttcggacagt
    80281 gattttgctg acttgaaaca gttcttctaa ttcactttct gtcggtaaca tcgaaccgac
    80341 tggatatttt cctgagaaaa tatcttcttt aattttatct gcgacttcca agtatagtac
    80401 acgtgtcctt ttcataacgt caccctttgc tttactatta ctaaaagaat agcacataaa
    80461 aaataaaaaa agaacacaaa tcacatgtga gaagtgtgtt ctttttcatt cagctgcttt
    80521 aattacaagt ttacgccatt tgaggcaatt acttctttat accaatcaaa agattttttc
    80581 tttgatcgat tcagtgtccc atttccttca tcgtctagat ccacatagat aaagccgtaa
    80641 cgtttactca tttctcctgt tgatgcactg acaagatcca tacatcccca aggcgtatag
    80701 cccatcaaat ctacaccgtc tgctactgca ttagccatcg cttcgatatg acgacgtaaa
    80761 taatcgatcc gataatcatc aataatcgtg ccatcctctt ccatatgatc aatggctcca
    80821 agaccgtttt caacaatgaa taatggtttc tggtaacgat tgtataattc attcaatgcg
    80881 attctcagcc cttctggatc gatctgccag ccccattcac ttgcctcaag aaacggattt
    80941 tttactcctc ccagcaagtt cccttctgaa gttgctgctt gtggatcagt ctcattgatt
    81001 gccgtagaca tataataact aaatccgatg tagtccactg gatattcttt tagcaactgg
    81061 aagtcttttt ccgtttgctc taatttttcc ggatcgactc catatttttt atgggtacgc
    81121 gctgtgtatg cagggtattc tccacgtact tggacatccg tgcagaaaaa attgaattct
    81181 tggttttgga tcattgttgc tgcctgattg actggattgg catcgatgct gtaagttgtt
    81241 gcatagataa tcatgcagcc gatttggata tccgaacgca attcgtggcc gatttttacg
    81301 gctttgctac ttgcaacgaa ttgattatgc catgcttgga aaatattttg gtactctcct
    81361 gctccattgc tttttactaa tccttgactt aaagctggaa agtgaaaggc cgaattgatt
    81421 tcattgaaag tcatccaata tttgacttta ctgctgtatc tctctaatac tgtctgagca
    81481 aatcgttcat agaagtcgat cagttttcga tttttccagc caccgtattc ttttgccaaa
    81541 tgaagaggca tttcgtaatg agaaatcgtg atcacaggtt caatatcata ttttaagcac
    81601 tcatcaatca gctgatcata aaattctaat cccgcttcgt taggagtacc ttcgtctcca
    81661 tttggaaaaa ttcgtgtcca ggcaatcgaa aaacgataac atttgaatcc catttccgca
    81721 aacaaggcaa gatcttcttt gaaacgatcg taatgatcaa ttcctcgatg attcgggtaa
    81781 atatattttt cttgatcaat cgtccagtca aattcttcac tgccgataat cgcaaagcgc
    81841 tgcttacctc caggcatagc atctgcaacg gatagccctt ttccgtctcg atcataagcc
    81901 ccttctaatt gattggcagc agttgctcca ccccataaaa atttttctga aaaacgtgat
    81961 tgcatcctga tttcctcctt attttacaat tgccagaaca tcttcgtttg caataatctc
    82021 tttttggtct aattcaagta tatcggcaaa tgcatcagta ttcgtaatga caactggagt
    82081 gattacgcta tagccagctg ctctaattgc ttcgatgtca aaacgaatca ataaatctcc
    82141 tgctttgacg agatcccctt gtttgactaa gatctcaaag ccattcccat ttaattctac
    82201 tgtatccatc ccgatatgaa tcaaaatctc cgctccgtca gtcgttgtga tccctacagc
    82261 atgtccagtt ggaaaaatag tcgtgatctc tccgtctgca ggtgcaacta gttctcctac
    82321 ttctggatca atagcgatac cttttcccat cacgccagaa gaaaaaactt ggtctggtac
    82381 ttcactcaat ggcagtactt tacccgttaa aggacttttt aaggtatgcc gtgctgaagt
    82441 aatcggttct cctgcattcg catgtttgtt ttctaattga ttgtcttgtg tttgttcgtc
    82501 aaatcctaaa atcaatgtac ctacgaatgc aagaacaaaa gcaattcctg tagctattac
    82561 tgctactgtc acatttgact ctacaccatc caccgtatta atgaaagtcg gaatcgtcaa
    82621 taagctgacc aaactgctgg agaaagcttt tactccggaa aatccgataa tagctccacc
    82681 aatacctcca gaaatacaag cggcaatgaa tggtttcttc aaaggtaatg tcacaccata
    82741 cacagttggt tcagtgattc caaataacga agtcactgta gaagaaatcc ctaatgctcg
    82801 aagtttcgta tcttttgttc gcaatgctac agctaaagca gccccacctt gtgccaagat
    82861 ggctggaaga agcattggca tcaatacatc aaacccatat tgttcgatat tcaaaaacat
    82921 gatcggtacg aatccccaat gcatgccgaa catcacgaat acttgccata aacttcccat
    82981 gattagacct gctacgattg gactaaatcc ataaatcgag ttgaagagac cgcctaaagc
    83041 attaccggca accgtcccga ttggtcctaa agcaagaaat gttaatggaa ccatcactac
    83101 taaaacgaca agcggaacta aaatcatttg cagaaattgc ggaatcactt tttttacgaa
    83161 tggctctaat ttactttgaa cccatacggc tagaatgatt ggtatgacag aagaagtata
    83221 accagatggt gaaagaatca ctgggatccc aaagaaactg atagcttctc ccgcaccagc
    83281 aactgctgtg atagctggat acacaagtgc catagcaatt gctactgcta aaaactggtt
    83341 ggctttgaac tttttagctg ctgtaaaagc aagcatgaca ggtaagaagg taaagacacc
    83401 atctgctgca gcaaacaata tttgataagt accgctatca gctgtcagcc agcccatcac
    83461 cgttgccaat gataagaatc ctttcaatac cccggcggct gccatcgccc ctagaaaagg
    83521 tgtaaatata ctagagataa tatcgatcag acgattcaaa atatttttgg actcttcttt
    83581 tccatcctcc gaaactgcaa gaccttcctc atccacgatc gattgataaa catctgctac
    83641 attactgcca atcactactt gatactgacc gccactttgt acgacttgga tcacgtccgg
    83701 gtcttctttt aacttttgcg tatctgctaa agattcatct tttaatctga atcgcaaccg
    83761 cgtagcacaa tgtactaaac ttttgacatt cttttgtcct cctaccgctt cccatacacg
    83821 acgaccaact gcttgattat ccattgtttt ttccttcttt ctttttt
//
LOCUS       DAFELK010000006        76756 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFELK010000006
VERSION     DAFELK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 76756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76756
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.006"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            476..1339
                     /locus_tag="LP433_000552"
     CDS             476..1339
                     /locus_tag="LP433_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2004743.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="LP433_000553"
     CDS             complement(1468..3090)
                     /locus_tag="LP433_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2004744.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="LP433_000554"
     CDS             3339..3860
                     /locus_tag="LP433_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL2004745.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="LP433_000555"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="LP433_000555"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBL2004746.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="LP433_000556"
     CDS             5941..6759
                     /locus_tag="LP433_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBL2004747.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="LP433_000557"
     CDS             complement(6862..7059)
                     /locus_tag="LP433_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004748.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="LP433_000558"
     CDS             7228..7806
                     /locus_tag="LP433_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL2004749.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="LP433_000559"
     CDS             7901..8038
                     /locus_tag="LP433_000559"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004750.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="LP433_000560"
     CDS             complement(8851..9354)
                     /locus_tag="LP433_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL2004751.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="LP433_000561"
     CDS             9713..10738
                     /locus_tag="LP433_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2004752.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="LP433_000562"
     CDS             11061..11939
                     /locus_tag="LP433_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBL2004753.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="LP433_000563"
     CDS             12415..12531
                     /locus_tag="LP433_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL2004754.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13460..13798
                     /locus_tag="LP433_000564"
     CDS             13460..13798
                     /locus_tag="LP433_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004755.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13892..14122
                     /locus_tag="LP433_000565"
     CDS             13892..14122
                     /locus_tag="LP433_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004756.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14522..14893
                     /locus_tag="LP433_000566"
     CDS             14522..14893
                     /locus_tag="LP433_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBL2004757.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15167..15859)
                     /locus_tag="LP433_000567"
     CDS             complement(15167..15859)
                     /locus_tag="LP433_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2004758.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15862..16647)
                     /locus_tag="LP433_000568"
     CDS             complement(15862..16647)
                     /locus_tag="LP433_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2004759.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16884..18284
                     /gene="lacG"
                     /locus_tag="LP433_000569"
     CDS             16884..18284
                     /gene="lacG"
                     /locus_tag="LP433_000569"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBL2004760.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18309..18626
                     /locus_tag="LP433_000570"
     CDS             18309..18626
                     /locus_tag="LP433_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2004761.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18639..20312
                     /locus_tag="LP433_000571"
     CDS             18639..20312
                     /locus_tag="LP433_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBL2004762.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20326..21957
                     /locus_tag="LP433_000572"
     CDS             20326..21957
                     /locus_tag="LP433_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBL2004763.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22448..24013)
                     /gene="guaA"
                     /locus_tag="LP433_000573"
     CDS             complement(22448..24013)
                     /gene="guaA"
                     /locus_tag="LP433_000573"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBL2004764.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24072..24995)
                     /locus_tag="LP433_000574"
     CDS             complement(24072..24995)
                     /locus_tag="LP433_000574"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBL2004765.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25191..25796
                     /locus_tag="LP433_000575"
     CDS             25191..25796
                     /locus_tag="LP433_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2004766.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26104..27120
                     /locus_tag="LP433_000576"
     CDS             26104..27120
                     /locus_tag="LP433_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL2004767.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27261..28562
                     /locus_tag="LP433_000577"
     CDS             27261..28562
                     /locus_tag="LP433_000577"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBL2004768.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28608..29270
                     /gene="deoC"
                     /locus_tag="LP433_000578"
     CDS             28608..29270
                     /gene="deoC"
                     /locus_tag="LP433_000578"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBL2004769.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29291..29689
                     /locus_tag="LP433_000579"
     CDS             29291..29689
                     /locus_tag="LP433_000579"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBL2004770.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29755..30837
                     /locus_tag="LP433_000580"
     CDS             29755..30837
                     /locus_tag="LP433_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2004771.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31049..32611
                     /locus_tag="LP433_000581"
     CDS             31049..32611
                     /locus_tag="LP433_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004772.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32604..33737
                     /locus_tag="LP433_000582"
     CDS             32604..33737
                     /locus_tag="LP433_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004773.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33737..34693
                     /locus_tag="LP433_000583"
     CDS             33737..34693
                     /locus_tag="LP433_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004774.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34792..35958
                     /gene="deoB"
                     /locus_tag="LP433_000584"
     CDS             34792..35958
                     /gene="deoB"
                     /locus_tag="LP433_000584"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBL2004775.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35982..36800
                     /locus_tag="LP433_000585"
     CDS             35982..36800
                     /locus_tag="LP433_000585"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL2004776.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36817..37524
                     /gene="deoD"
                     /locus_tag="LP433_000586"
     CDS             36817..37524
                     /gene="deoD"
                     /locus_tag="LP433_000586"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL2004777.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37822..38508)
                     /gene="gpmA"
                     /locus_tag="LP433_000587"
     CDS             complement(37822..38508)
                     /gene="gpmA"
                     /locus_tag="LP433_000587"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL2004778.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38680..39261)
                     /locus_tag="LP433_000588"
     CDS             complement(38680..39261)
                     /locus_tag="LP433_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2004779.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39394..40077)
                     /gene="rpiA"
                     /locus_tag="LP433_000589"
     CDS             complement(39394..40077)
                     /gene="rpiA"
                     /locus_tag="LP433_000589"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBL2004780.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40396..40809
                     /gene="rpsL"
                     /locus_tag="LP433_000590"
     CDS             40396..40809
                     /gene="rpsL"
                     /locus_tag="LP433_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBL2004781.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40893..41363
                     /gene="rpsG"
                     /locus_tag="LP433_000591"
     CDS             40893..41363
                     /gene="rpsG"
                     /locus_tag="LP433_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBL2004782.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41457..43544
                     /gene="fusA"
                     /locus_tag="LP433_000592"
     CDS             41457..43544
                     /gene="fusA"
                     /locus_tag="LP433_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL2004783.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43716..44903
                     /gene="tuf"
                     /locus_tag="LP433_000593"
     CDS             43716..44903
                     /gene="tuf"
                     /locus_tag="LP433_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL2004784.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45310..45618
                     /gene="rpsJ"
                     /locus_tag="LP433_000594"
     CDS             45310..45618
                     /gene="rpsJ"
                     /locus_tag="LP433_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBL2004785.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45649..46278
                     /gene="rplC"
                     /locus_tag="LP433_000595"
     CDS             45649..46278
                     /gene="rplC"
                     /locus_tag="LP433_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBL2004786.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46306..46929
                     /gene="rplD"
                     /locus_tag="LP433_000596"
     CDS             46306..46929
                     /gene="rplD"
                     /locus_tag="LP433_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBL2004787.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46929..47219
                     /gene="rplW"
                     /locus_tag="LP433_000597"
     CDS             46929..47219
                     /gene="rplW"
                     /locus_tag="LP433_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBL2004788.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47258..48091
                     /gene="rplB"
                     /locus_tag="LP433_000598"
     CDS             47258..48091
                     /gene="rplB"
                     /locus_tag="LP433_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBL2004789.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48134..48412
                     /gene="rpsS"
                     /locus_tag="LP433_000599"
     CDS             48134..48412
                     /gene="rpsS"
                     /locus_tag="LP433_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBL2004790.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48435..48782
                     /gene="rplV"
                     /locus_tag="LP433_000600"
     CDS             48435..48782
                     /gene="rplV"
                     /locus_tag="LP433_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBL2004791.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48796..49452
                     /gene="rpsC"
                     /locus_tag="LP433_000601"
     CDS             48796..49452
                     /gene="rpsC"
                     /locus_tag="LP433_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBL2004792.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49455..49889
                     /gene="rplP"
                     /locus_tag="LP433_000602"
     CDS             49455..49889
                     /gene="rplP"
                     /locus_tag="LP433_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBL2004793.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49879..50067
                     /gene="rpmC"
                     /locus_tag="LP433_000603"
     CDS             49879..50067
                     /gene="rpmC"
                     /locus_tag="LP433_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBL2004794.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50092..50358
                     /gene="rpsQ"
                     /locus_tag="LP433_000604"
     CDS             50092..50358
                     /gene="rpsQ"
                     /locus_tag="LP433_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBL2004795.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50416..50784
                     /gene="rplN"
                     /locus_tag="LP433_000605"
     CDS             50416..50784
                     /gene="rplN"
                     /locus_tag="LP433_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBL2004796.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50821..51129
                     /gene="rplX"
                     /locus_tag="LP433_000606"
     CDS             50821..51129
                     /gene="rplX"
                     /locus_tag="LP433_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBL2004797.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51157..51696
                     /gene="rplE"
                     /locus_tag="LP433_000607"
     CDS             51157..51696
                     /gene="rplE"
                     /locus_tag="LP433_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBL2004798.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51715..51900
                     /locus_tag="LP433_000608"
     CDS             51715..51900
                     /locus_tag="LP433_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBL2004799.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51936..52334
                     /gene="rpsH"
                     /locus_tag="LP433_000609"
     CDS             51936..52334
                     /gene="rpsH"
                     /locus_tag="LP433_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBL2004800.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52366..52902
                     /gene="rplF"
                     /locus_tag="LP433_000610"
     CDS             52366..52902
                     /gene="rplF"
                     /locus_tag="LP433_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBL2004801.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53063..53419
                     /gene="rplR"
                     /locus_tag="LP433_000611"
     CDS             53063..53419
                     /gene="rplR"
                     /locus_tag="LP433_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBL2004802.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53440..53940
                     /gene="rpsE"
                     /locus_tag="LP433_000612"
     CDS             53440..53940
                     /gene="rpsE"
                     /locus_tag="LP433_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBL2004803.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53955..54134
                     /gene="rpmD"
                     /locus_tag="LP433_000613"
     CDS             53955..54134
                     /gene="rpmD"
                     /locus_tag="LP433_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBL2004804.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54178..54618
                     /gene="rplO"
                     /locus_tag="LP433_000614"
     CDS             54178..54618
                     /gene="rplO"
                     /locus_tag="LP433_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBL2004805.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54618..55913
                     /gene="secY"
                     /locus_tag="LP433_000615"
     CDS             54618..55913
                     /gene="secY"
                     /locus_tag="LP433_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBL2004806.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55975..56622
                     /locus_tag="LP433_000616"
     CDS             55975..56622
                     /locus_tag="LP433_000616"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBL2004807.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56813..57031
                     /gene="infA"
                     /locus_tag="LP433_000617"
     CDS             56813..57031
                     /gene="infA"
                     /locus_tag="LP433_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBL2004808.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57064..57180
                     /gene="rpmJ"
                     /locus_tag="LP433_000618"
     CDS             57064..57180
                     /gene="rpmJ"
                     /locus_tag="LP433_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBL2004809.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57198..57563
                     /gene="rpsM"
                     /locus_tag="LP433_000619"
     CDS             57198..57563
                     /gene="rpsM"
                     /locus_tag="LP433_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBL2004810.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57591..57980
                     /gene="rpsK"
                     /locus_tag="LP433_000620"
     CDS             57591..57980
                     /gene="rpsK"
                     /locus_tag="LP433_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBL2004811.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58060..58998
                     /locus_tag="LP433_000621"
     CDS             58060..58998
                     /locus_tag="LP433_000621"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBL2004812.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59026..59406
                     /gene="rplQ"
                     /locus_tag="LP433_000622"
     CDS             59026..59406
                     /gene="rplQ"
                     /locus_tag="LP433_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBL2004813.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59678..60517
                     /locus_tag="LP433_000623"
     CDS             59678..60517
                     /locus_tag="LP433_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2004814.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60493..61362
                     /locus_tag="LP433_000624"
     CDS             60493..61362
                     /locus_tag="LP433_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2004815.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61352..62149
                     /locus_tag="LP433_000625"
     CDS             61352..62149
                     /locus_tag="LP433_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL2004816.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62352..63098
                     /gene="truA"
                     /locus_tag="LP433_000626"
     CDS             62352..63098
                     /gene="truA"
                     /locus_tag="LP433_000626"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL2004817.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(63553..66222)
                     /locus_tag="LP433_000627"
     CDS             complement(63553..66222)
                     /locus_tag="LP433_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBL2004818.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(66460..66648)
                     /locus_tag="LP433_000628"
     CDS             complement(66460..66648)
                     /locus_tag="LP433_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBL2004819.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            66918..67280
                     /locus_tag="LP433_000629"
     CDS             66918..67280
                     /locus_tag="LP433_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2004820.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            67332..69014
                     /locus_tag="LP433_000630"
     CDS             67332..69014
                     /locus_tag="LP433_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBL2004821.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            69131..71167
                     /gene="recG"
                     /locus_tag="LP433_000631"
     CDS             69131..71167
                     /gene="recG"
                     /locus_tag="LP433_000631"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBL2004822.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            71216..72217
                     /gene="plsX"
                     /locus_tag="LP433_000632"
     CDS             71216..72217
                     /gene="plsX"
                     /locus_tag="LP433_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBL2004823.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            72339..72581
                     /gene="acpP"
                     /locus_tag="LP433_000633"
     CDS             72339..72581
                     /gene="acpP"
                     /locus_tag="LP433_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL2004824.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            72849..73853
                     /locus_tag="LP433_000634"
     CDS             72849..73853
                     /locus_tag="LP433_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004825.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            73854..74798
                     /locus_tag="LP433_000635"
     CDS             73854..74798
                     /locus_tag="LP433_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004826.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            74798..75760
                     /locus_tag="LP433_000636"
     CDS             74798..75760
                     /locus_tag="LP433_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004827.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            75787..76701
                     /locus_tag="LP433_000637"
     CDS             75787..76701
                     /locus_tag="LP433_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004828.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
BASE COUNT        24430 a        13787 c        16374 g        22165 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgttttattt tccctctgtt
    13441 tagccaagta acattttcta tgactcaacc agtttcaagt gaggaacatg ataacctttt
    13501 tcgtgctaca gaagagttta agaaatatca ggaaaatatt gttccggaga ctccattagc
    13561 tagtgagcca attactgata ttgatggaaa ccaaatagga tggtatatac agtacgaagt
    13621 tatggtggta aataatgact caatagtaaa aaatacagta ggcttagagc taacaccgat
    13681 tgaaaaggtg agttcattgt taacgtatat ttatactgat gaaagtgacg agactgagat
    13741 cattttaacg gattactcaa aaattgctac tgataaaaag tatatattgt ggatgtagac
    13801 actagtgaaa tactttatga tatagaaatt gatgaaaatt tactagatgt agcacaagaa
    13861 atcgatcatc aaaagcagga agctattcga tatgctggta gaaaagggaa aagaaaatat
    13921 ttattacgtg aatgtagcaa aagttagaga agatgaaaat gagtggaaag aattcaagag
    13981 tcgctactca attaactcga ctccgacatt tacagtttac agagaaggat cgatagaaaa
    14041 aactgttttt tggactaaag aaagtggaat gtctttagct gaagtagaag agtttttgga
    14101 ttatgttagt atgcaacagt aagggagttc ttattatgaa aaattttgac acatattatg
    14161 ttattgtttt ttcgatatct ttgctgttaa tattactaac tttaatgcag tataaagagt
    14221 atccagagta ttttatttta acttttgtat atttagtaag tagctacaca cttctatata
    14281 aattcagaag ttcttctaga gtttctaaag tttgtttctt aattagctta ttgattctat
    14341 aatatttttg atttatatag gaaattaaaa atattataga atcaacactc agagaacggg
    14401 ttggttttta atagatttaa taagtactga taatgaaatt tctcctggtt gggaaaacga
    14461 agttggttac cctgtagaag aattttttca agattacttt gcggagtatg ccgataggat
    14521 aatgagagat tacgtaacag ataaaactca agaagtcatc aatcaatccc agtcattaaa
    14581 tgaattatct gataaggcga aagaagaagc agttgccatt atttcttcag ggattagtga
    14641 ctatattgat atgagtggtg aaatcaatta tggcgataaa gacaaaattg tacgcatgat
    14701 aaaagctttt atcaaaactt ttgatgtgaa ggcagatctt aagtttaatg atacttacct
    14761 agtaggaaaa ttaattaata tccttgggac agagaaagat acggaaacgt ttatttcctc
    14821 tttgtctatg ttgtttacag ataagcattt ttcaactcag cttggtggag aggaactagt
    14881 ggaaatcttt taaccattac gcccagcatt aataaaagta tatcaaaaaa gtactcctga
    14941 tgatttttaa gattggtttg agaaataatg tgaaaacact atttttaatg ttaattatag
    15001 atagagatga acgcgtcata tggttaaaag aatgaaaaag tcaaagatac actgctatat
    15061 ttcactaagg atatagcagt gtatctttca tgtcgtttca ctggcagttt tttataaaag
    15121 gaggtgtgca tttcagttgc ttttctttgg tagttagttg aatcgtttaa gaattaacgg
    15181 atgtggcaga caggtgctct gtccaaaaac cagtaaaatc tttgatggtt ccatctttat
    15241 ttagctgtgc ctgttcaaat actgttttgt ttttaccgaa tggatcaatt gcaataattg
    15301 ttccgatccc cgcacgtttg gcagcaagta atcctgagta agcatcttcg ataacaagac
    15361 aatcagccgg agctaagctc agtttgtctg ccgctttaag aaaaatatcc ggttgcggtt
    15421 tcccagggaa agagccgtcg tcatagacaa tcttgtccca gtcaaaccag cgggctaaat
    15481 cgaaaatatc aaaataaaaa gcaacattct ctttgacagt agccgtggca atcgttaatg
    15541 gaatctgttg gtcagtcagc tggtcaagag tcgcttcaag cccttttgtc aactgaagct
    15601 cgttttcatt ttgcaagcaa agcatacgat aatagctttc tttttcttct gacaatacgg
    15661 cgatctcaga ggcggtcaaa tgctctgaaa tgaaatgttt caaaatctcc gtattcgtcc
    15721 gaccatgaat attttttaaa atatcctcgt ctgataaacc atcttttgta tgatcatgta
    15781 tcatatgcag ccaagcagct tcatgcagat gagagtccaa aaacattgtt ccgttgaaat
    15841 caaatataat ccctttcata gttacgctcc tatagtggta ttttcggttg aatcagcaat
    15901 ttgcagatcg acatattgtg catagtgctc ttgaacctcc cgcgagatct ggcgatccgt
    15961 aatgagcaga tcgaaatcat gcaaattata aaacacataa aaatcatctc gattgaattt
    16021 tttattatca acgagtagat atttcttacg ggaattattt agagcgatct gctgtgcttc
    16081 tccttcttcg gtactgtaag tagagatcgc ttcgttgtga acgccatttg aactgataaa
    16141 tgcttttgta aactttagtc ttcttaaatt gtcgttggtg atcggtccga caaatgcgcc
    16201 ggtatttttc cggaaatcac cgccaatcag tagaatttct ggtccatctg cttgagcaag
    16261 aatatcaaaa actggataat tatttgtaat gatccgaatt ttcttgttca gtaaatgcgt
    16321 cgccaatagt tcgattgttg tacctggtcc taagaaaatc gtttctccct cgtgaatcaa
    16381 ggaggctgct gtggcagcaa tttctttttt ttcttgaatc tgcagagtgg ctttttcagt
    16441 gtgagaaagt tcttgatcta aagtgtagga aagactttga gcccctccat ggacacgcag
    16501 cagcttgccc gatttttcta attcatctaa atctctgcga acggtcatat cagaaacatc
    16561 taattgattg atgatttcat taacggtaag gattcctttt ttattgacca tttctacgat
    16621 agtaagcaat ctttcttttt tcaacattgt cttcacctct aatttaagga taatctatca
    16681 tataaacgga caacagtcaa tctaattcga acaaaagtaa acatttaggg tggtttttat
    16741 gtttgttaca atagatttta ttgctgtttt ctggttttta tgattatttg tgtttgtttt
    16801 tgttgacaaa tgttttggat gcgtttacaa tgcaatcagt tagaaagagc gaaaactgat
    16861 tatagatttg aggagagatg tacatgctta aattaccaga agattttatt tttggcggag
    16921 ccacagcagc ctatcaggtt gaaggagcca ctaaggaagg tggcaaaggc gctgttgctt
    16981 gggatgactt tttagaggaa caagggcgat tcagtcccga tccggcaagt gatttttatc
    17041 atcaatatgc aaaggacatt gaattgtgtg aacgttttgg tgtaaatggt ctaagattat
    17101 ccattgcttg gagccgcatt tttcctgatg gagctgggaa accaaatcca gaaggaatcg
    17161 ctttttatca tcgtgtgttc gaagaatgta agaaaagaaa cgtaacgccg tttgtgacgt
    17221 tgcatcattt tgatacccct aaacgtttgt ttgaccatgg agattttttg aatcgagaaa
    17281 caatagaagc atttgtttcc tatgccattt tttgttttca tgaattcaaa gaagtcaagg
    17341 tgtggagtac ctttaatgaa atctatccag ttgcaaccaa tcaatatttg ttaggtgttt
    17401 tcccaccagg aatcaaatat gattttacaa agatcgtcgc ctgtcttcat aatatgatgg
    17461 ttgctcatgc ccgtgtagtg aactatttca aagaaaacga acttccgggt gaaattggtg
    17521 tagttcactc attagagacg aaatatgcgg caacagacgc gccggaagat aagcatgctg
    17581 cctttttaga cgatgcattg tcgatccgtt tcttattaga tgctacctat ttaggctatt
    17641 attcaactga aaccttgact gctcttgatg agatatgtga agcaaatcag gccagctatc
    17701 attttcctga agaagatttc gttgaattga aaaaagcatc cacgcgtaat gactacttag
    17761 ggatcaatca ctaccaatgc cattttgtca aagcttacga tggagaaaat gcaatccatc
    17821 ataacggtac gggtgaaaaa gggacctctg tttataaagt gaagggaatc ggagaacgta
    17881 tttataaaga aggaattcct cgaactgatt gggactggct gatttatcca gaaggtctat
    17941 atgacttgtt gctgcgaatt aaaagcgatt acccacatta caacaaaatc tatatcactg
    18001 agaacgggat ggggtataaa gatcagtttg aagatggcat tattatggat cagccgagaa
    18061 tcgactattt gagagtctat ttggaatcct taagcaaggc gataacagcc ggggtaaatg
    18121 tgaaggggta ttttttgtgg tcgcttatgg atcttttctc atggacaaat gggtataaca
    18181 aaaggtatgg cttgttttat gttgattttg aaacccagaa gcgttaccca aaagaatcag
    18241 cttactggta caagttggtc agtgaaacca aaacgattat ttaataagtg ataatggagg
    18301 aagaaaagat gaataaagag gaattacaaa tgcttggttt tgagatcgtt gcatattcag
    18361 gcgacgctcg cagtacatta ttgaaattat tgaaagaagt aagacaagga aactttgaac
    18421 atgttgattc ggcgttgaaa gaagccgacg aaaatttaac ccttgcacat aattcgcaaa
    18481 caaaaatttt agcggaagaa gcatctggga aagagatgga gatgggattc atttttatcc
    18541 atgggcagga tcatttaatg accactttat tgctgagaga tctgattcaa gactttattg
    18601 tactgtacag acagaatcaa ggataggaga agaacgctat ggatggaatc attaaacaaa
    18661 tcgaaaaagg gaaaccattt tttgaaaaaa tctcacgtaa tagttattta ggagccgttc
    18721 gtgacggatt tttaacagcg atgccagcta ttttattttc aagcattttc attttgattg
    18781 ctgcggttcc tgagattttt ggttaccaat ggcctgaatc tgtctccaca tggctatgga
    18841 aagtctataa ttattcgatg ggtgttgtag ggttactcgt ttcagcaacc actgctcgct
    18901 gcttggctga ttcgatgaat cgtcgcttac cgaaaaacaa agtaatcaac accacctctg
    18961 tgatgctggc ctctgtggta agtttcctgt tgttaagcgt ctctccgatt gaaggtggat
    19021 tttcaacgga atatatgggg acaaagggac tactggcttc ctttgtcgct gcatttttaa
    19081 cagttaattt atataagttt tgtgtgctga aagatattac cattaaaatg cctaaagaag
    19141 ttcctggaac gatttcgcaa accttccgag atatttttcc tttctctttt tcagtatttg
    19201 cggccgtttt aattgattta ggcattcgac aaatcttcca aatctcattt gcagaagcaa
    19261 tcattacggt gctgcagccg ctatttacag cagctgacgg gtacttagga atcgctatta
    19321 tctggggagc gatggcgctg ttttggtttg tcggtgttca tggaccgtcg atcgtggagc
    19381 cggcaattgc ggcaattatc tatgccaatg tggaaaccaa tctgcaattg ttcaattccg
    19441 gtgaacaagc ttctaaagta ctgacggtgg gtttagggaa ttttgtagga actatgggag
    19501 gaactggggc aacattggtt gttcctttta tcttcctact ctttgctaag tctaagcagt
    19561 tgaaggcagt tgggaaagct tcctttattc cagtaagttt cgctgtcaac gaaccattgc
    19621 tatttgcggc acccatgatt ttgaaccctt atttttttat tccatttttg ttaacacctg
    19681 ttgtaaacgt ttgcctgttc aagttttttg tcgatgtatt gggcatgaac agctttatgt
    19741 acgttttgcc ttgggcaact ccagcaccga tcggtttggt tctaggaacg ggcatgggta
    19801 tcttagcttt tgttctagca gcggttctaa tcgtcgttga cttcctgatc tatctaccat
    19861 tttgcaaagc atacgatgct gtcttagtag agaaagaagc acaaaaagca gaggtgatcg
    19921 caaccgagga aggtgcttct gccgatgtac gtgaggaagt acctgtggca gcgagtcaag
    19981 ttatcagcga tgcaaataaa gaaatcaatg tgttggtact ttgtgctggc gcagggacaa
    20041 gtgcgatgtt agctaatgct ttaaaaaaag gtgcatctga atcgaaagca ccgatcagtg
    20101 caatggcggg tgcttatggt tctcattacg aaatgctgca ggattttgat atggtggtct
    20161 tagcaccgca agtcaattct tactatgatg atatcaaaga agacaccgat cgcttaggaa
    20221 tcaagctggt tgcgacaaaa ggagcagaat atatcggatt aacgagagat cctgaaaaag
    20281 ctgttcagtt tattctgaac caatttcaat aaaggaggag ccataatgaa aatgggaatt
    20341 tggttgcgta aagctgtttt atttgcagct gtgttagggg ctttgggggc tgtttcaaaa
    20401 actgttgaag catctgccag cgaatttatt cgcggagcag atatttcgat cctgtcagat
    20461 atggaaaaat ctggtgcaaa atattatgaa gacgatattt caaaagatgc cttagagatt
    20521 ttaaaaaata atggtgtcaa ctatgttcga ctgcgtttgt ggcaggatcc ttataatagt
    20581 aatggagaaa gttatggagc agggacaaat gatctggaaa cgacgattga ccttgcaaaa
    20641 cgagcaaaaa atctgggact taaggtgctg ctggattttc actacagtga tttttgggtt
    20701 gatcctggga aacagaatct tcctaaagca tggcaaggtc tgacctttga agaaatgaat
    20761 acggcattgt acgactatac aaagaacgtt ctgtcggaaa tgaagcagct ggacgtttat
    20821 cctgatatgg ttcagatcgg caatgaactg aatagcggaa tgctctggcc ttatggcaag
    20881 tcttggggag aaggcggggg agaatttgat cgattggctg cttttttgaa gtctggtatc
    20941 caagctgttc gagacactca acctaaaaca actccagtaa tgctccactt agctgatggt
    21001 ggcgatacag gagcatttac ttggtggttt gatgaaatca cgagtcgagg tgtgtcattt
    21061 gatttaattg gagtgtcgta ttatccgtat tggcacggtt caatgaatga acttcaaacc
    21121 aatatgaatg cgatcagcca acggtatggt aaagaagtga tcgtagttga aacagcttat
    21181 gggcatacaa cagcgaatgc cgatactatg ccaaatgctt ttggtgaagc cgaagcagct
    21241 gcggggggat atgaaccaac accgacagga caagcagagt atttgctgga tcttgccgat
    21301 cggattcagg cagtaccgaa taatcgcggg gcgggcttct tctattggga acctctttgg
    21361 tacaacggaa atgtgagttg ggcaacacaa gcaggtatga attatctcag tgttcaatcc
    21421 actatgggaa acgaatggga caaccaagcg atgtttgatt ttgctggaaa cgccttgcca
    21481 agcttgcgtg cgtttaaaca agcaggggcg caaataaatc tagttaaaaa tgcaagtttc
    21541 gaaagcgatg gaccaacgac cagtccttcc aattggcaaa cctggtttca acaaggaacc
    21601 gctaagggta cgatcaaaac ggaagcgggc actttttttg gggactacaa actaactttt
    21661 tggcaggatc aagcatacga ggcatcagct tatcaaaatg ttagtggcat aagcaaagga
    21721 acttacacat tgagtgccta tgtaatgtct gggggagagt ttgatactaa tcagttatat
    21781 atcaaaaatt atggtggagc ggaactaaat actgcggttg ttaaaacaag tgaatggaca
    21841 aaaattacaa tcaaagacat tccaattaca acaggtgttt gtgaaattgg ggtttatagc
    21901 aaggcttcag gaaatgcttg gacgaacgtt gattttgttt cattggtgaa acaatagact
    21961 gcggatcgtt tcgattcaag atcggaggtt cccttcagcc acatcgttag cgtagaaggc
    22021 aggaatcgaa cctgcacctc gcctttgcca aaaataacca gaaacgattt ccagtcattt
    22081 ttaccaaaac gagtaaagca ccagacttca tctacacttt gtattatgct aaagagagtt
    22141 caacgatttc gtaagaagca atgaaaaaat tgcaaaaagt tgtgcagata acataaagtt
    22201 tgtttaagaa agggtaacct tagaattccg tcgtgaatat gatttgagca cttagatgga
    22261 tagaaaaaag ttctcggaaa acagttcgtt tttcgagaac ttctttttat gataagaatg
    22321 aaacaaatta acttatatta tagtctcttt tggtagggaa ccatcttatt tttaatgaaa
    22381 atcaagcatt ttagctattg aagaatgttg atttataggg attccccctc catattatgt
    22441 tggctcttta ttcccactcc actgttgctg gtggtttaga agtgatgtca tacacgatac
    22501 ggttgacgtg ggctacttcg tttacgatac gtacagagat tttttgcaag acttcccatg
    22561 ggatacgggc aaagtcagcg gtcattccgt cgattgaagt tacagcacgg ataccgactg
    22621 tgtagtcgta agtacgtccg tcacccataa caccgacaga gcggatccct ggaagaacag
    22681 tgaaatattg ccagatatca cggtcaagtc cagcagctgc gatttcttca cgcaagatag
    22741 catcagattc gcgtacgatt tctagcttgt cttcagtgat ttcgccaaga acacgaatac
    22801 caagaccagg accagggaat ggctgacgcc aaacgattga atcaggcatg cctaactgag
    22861 tccctaattc acggacttcg tctttgaata atgtgtttaa tggttcgatc aattcaaatt
    22921 gcatatcttc tggcagtcca cctacattat ggtgagattt gatcgtctgt gctgtttctg
    22981 taccagattc gataacgtca gtatacaacg ttccttgtgc taggaaagag acgccttctt
    23041 caccagcaag ttttgttgct tcgtcatcaa aaacatatac gaattcattc ccaatgattt
    23101 tacgtttttg ttctgggtca gatacacctt tcaacttgtc taagaagcga tctcttgcat
    23161 tgactttgat gatgttcaag ccgaattttc cgcctagact ttccattact tgttccgctt
    23221 cgcctttgcg tagcagaccg tggtcaacaa agatagatgt caattggtca ccgatcgctt
    23281 tttgtaaaag aaccccaacg acactagaat caacgccacc tgaaagacca agcaagactt
    23341 ttttgtcacc aacttgttca cggatttttt ctacttgcat atcgataaag ttatccattg
    23401 tccagttacc ttcacagtga caaacatcaa aggcaaagtg gcgcagcaat tcgattccgt
    23461 attcggaatg acgtacttct gcatggaatt ggataccata aaaattacgt gttgtgtctt
    23521 ggatagaagc aatcggacaa tctttgcttg ttccgactgt ttcaaagcct tcaggaactt
    23581 tagttaccaa gtcaccatgg ctcatccata ctgtttgttg ttttggtgtt tctttaaaca
    23641 agacagcttg atcgcttgtt acttctaaca aggctttccc atattcgcgg tttttagcag
    23701 gctctacgga accgccaagt ttgtacgtga tcaattgcat accatagcaa atccctaata
    23761 caggaatacc taaattgaag atctcaggat cgatcccaaa tgcattctca tcatatacac
    23821 tgtttggtcc gccagaaaga atgattccct ttggattcat cgcttttact tcttctgcag
    23881 taatgcggtg gctcaataat tcggaaaaga ctccaagatc acgaatacgt cttgtgatca
    23941 attggttata ctgactaccg tagtctaata cgataatctt ttcaacgttc gtcatatcgg
    24001 caacgtttgt caaatttatt acccctatcc ctttaaattt tatctcaaaa tagtcaaact
    24061 attttaaaat gctaatattt tcgcatgaaa atcgaatcga tgatatgatt ttcagtttta
    24121 tggagaatta tatcggctct tcctcgtgta ggcaagatat attcctgtaa atttttcaaa
    24181 ttcacatttt tccatacatc ttttgccatt ttaaaggctt cttcacgatc tccgatagca
    24241 aaacgataat aataattctc tggattttgg aaagccgtat ccagtaacgc accaaaacga
    24301 tccaaatacc atttttcgat cagcacggga tcggcatcga catagacaga aaaatcaaaa
    24361 aagtcgctga cgtagatttg ctgattcgca ggtaattgaa gcgtattgat cccctcaacg
    24421 atcaagatat caggctgctg gatcaattcg tacttgtctg gaatgatatc atacacatca
    24481 tgtgagtaaa caggtacttt tatctcttcc tgaccagatt ttacacggtt caagaaatcg
    24541 atcagcatct ccatatcata actttcagga aatcctttac ggtccatgat tccacgctct
    24601 tttaatatac gatttggata aagaaatccg tcagtcgtga tcagctgaac gtttcttcgt
    24661 ttgaaggtac gagacaaaat cgtctgcagc agtctggctg ttgtactttt tccaacggct
    24721 acacttccgg cgatcccgat aataaaaggc ggtacttcta cgtatttatg aagaaataaa
    24781 cctttactca agaacaaaga ttcaaattct ttcatataaa gataaatcag atgagcaaga
    24841 ggtacataga tatctcgaac atcctgcatg gaaatgcggt cattcaaact tttgatatta
    24901 tctagttcat cttgtgtcaa aggtgcttgc ccattacgat aaaattctcg ccattcttct
    24961 cttgccacac ggtagtagtt cattggatca ttcatattag cctcctgcgt tctcccatca
    25021 atggaactat tttaacacaa aataaacgca aaccccacca cttaagagag attgccgatc
    25081 tttttgtata atctttataa tagaaagaaa cggagtctta ttcttgactt gcgcacggat
    25141 acataaaagg atagactgtt gtcatgaaag aaatgagaag gatggaagac atgacaaatc
    25201 attactattc tgaacgccca gatacggcgc acgattttga acaatgggct tttgagttaa
    25261 aaggcagaac ctttcaattt gtaacagatt ctggtgtatt ttcacgtgaa acagtggatt
    25321 atggttcacg tgtcctgatt gatgctttcg attgggaaga gttacctgat gaaggaaaga
    25381 tcttagatgt gggatgcggg tatggaccga ttgggttagc tttggcattt gcgacacagc
    25441 ggtttgttga aatggtcgac attaatgaac gagcggtaag tctagcgcaa ggaaacgcaa
    25501 agcgtaacca aatcgaacat gttgatatcc atcaatcgaa tatctatgaa gcagttcatg
    25561 aagaaaccta tgcagctatc gtaagcaatc cgccgatccg tgctggaaaa aaagttgtac
    25621 atgaaatttt gacaggcgca tatcctcggt tgaagaaggg cggtacactg acaattgtga
    25681 tccagaagaa acaaggagcg ccgagtgcgc aaaagaaaat ggaagaaaca tttggtaatg
    25741 cagaaatcgt cacaaaagat aaaggatatt atatcatcaa aagtgtgaaa gaataactag
    25801 ctgaaaaata gtggagcgac gaaagagtgg aactgggcgt gcatgtacgg gtacgtatca
    25861 gttctttttt tgttgagaag tttttaaaaa caaagaacta ttttttcttc aaaaagaaat
    25921 agtaggaaca gagtcgttgt tttttacgat aaaataaata agatacagaa cttgtataga
    25981 aggctgccaa gtcggtagat aaaggaggtt tttatcaaaa aacatacttt ccttttttct
    26041 ctattctttt cttgggggtt ttggtacact gatagggaat ttagatagaa gggagccaat
    26101 aggatgaagc tgaccatcag agatatcgca gaaatggcag gcgtatcagt aacaactgtc
    26161 tcacagattt tgaataacaa aggaagcaga tttagtgata agacaagaaa aaaagtgttg
    26221 tcgatcgtga atgaacatca ttataagccc gattatttcg cttcaaatgt gatcaatcga
    26281 cattcaaaga ccatcggaat gatcgtccct gatgtcactg atttcttctt ctccaaactg
    26341 atcgaaggtg tagagagcta tttgaatcct ttgggctatg tgatcatgtt atgcaattct
    26401 cgtcatagcc aagaaaatga gatcaagtat ttacaagagc tttcccaccg ctcagtggac
    26461 ggaatcttgc tggccacacc aaatatttta cctgagaaat atgcattaga cagcggtttt
    26521 tatcaaaaaa tgccaatcat tttaatcgat cgcggattga atcgtcggga taacggacgg
    26581 cttatcgtaa aggaatatga gggcgcctat caagctgttt cgctgtttat tgaaaatggc
    26641 catacgaaga tcggcatgct gaaggaaacc actggatact atcaattaga agaacgtttc
    26701 aacggatatc gtcatgcgct gaaagatcat ggcctgcctt ttaatgggaa atttgttgaa
    26761 catggagagt tgactgtcca aggtggatat actgcatcaa aaaaattact caaacataaa
    26821 gatatcacgg ctattttttg cgggaatgat gccatggcga tcggatgcta tcaggcgatc
    26881 gatgaattgg gcaaaaaaat cccagaagat atctcagtca taggattcga tggattaaag
    26941 ctgtcagaat acatgattcc gcaattgacg acagtgcagc agccaagttt tgatattgga
    27001 ttttatgctg cacgtttcct gatcgatacg atcgaatttc ctcaaagaaa agttccgaac
    27061 aaagtgttcg aaacaaaatt aattattcgt gagagcgtaa aagtattgac aaagggctaa
    27121 ctcggcggta tattgcttat gtaagcattt acaaaggcta gttagtgctt tttttatttt
    27181 tagtaaacca gtttactaaa gtggtttacc tttcctaaaa ataatgtata ataccgaatg
    27241 aagacaagga ggatcaggca atgcgaatgg tggatctgat tgaaaaaaag agggatggaa
    27301 acgagctgtc gaaagaggaa atcgagtaca tcgtcacgaa ctatacgaat ggaaagattc
    27361 cagattatca agtcagtgca ttattgatgg caatttttta tcaagacatg acaaatgaag
    27421 aaatcacgaa cttaacattg gcgattgcta attctggtga tgtcatcgat ttgagttctc
    27481 ttgaaggaat aaaggtagat aagcattcga caggtggcgt tggtgacacg accacattga
    27541 ttttagcccc cctagtagct agtgtcggag tgacagtggc taaaatgtct ggacgcggtc
    27601 taggttacac aggtggtaca ctagacaagc tagaagcaat tcccggattt cagatcgagc
    27661 tttcggatga agaatttgta cgcattgtta atgaaagtaa agtagcggta attggtcaat
    27721 caggaaactt ggcaccggcg gacaaaaaat tgtatgcctt gcgtgacgtc acagcgaccg
    27781 ttgattctct tccgctgatt gccagttcga ttatgagtaa aaaaatcgcg gcaggagcag
    27841 atgcaatcgt tttggatgtg accactggag acggtgcttt catgaagaac atcgaagatg
    27901 caagacgtct ggcaaagacc atgacgagca ttgggaaact ggctaaccga gaaacagtgg
    27961 cggttatctc agatatgtca gaacctcttg gcgaagctat cggaaatagt ctagaagttg
    28021 tcgaggcaat cgaaacatta caaggaaatg gtccagaaga tctagtagaa atgtgctacg
    28081 ccttaggaag ccaaatggtt gttcttgctg gcaaagctaa gacaaccgat gaagcaagaa
    28141 cgttgcttca agaagctctg gaatcaggta aagcgttagc aaaattcaaa gaaatgatcc
    28201 aaaatcaagg gggagaccca gcgatcgtgg aacatccaga acgaattttg actgcacgct
    28261 acacaatgga gcttcctgct aaacaaagcg gagttgtgtc aaaaatcgtg gcaaatgaat
    28321 taggaattgc tgcaatgatg ctaggtgctg ggcgtaaaac caaagaagaa gatattgatc
    28381 acgctgttgg attgaaactg cataaaaaaa ttggtgacac tgtgacaaaa ggtgagtcac
    28441 tattgacgat ctatagtaac gacgaagaaa tcacttctgt cattgaatta ttatataaaa
    28501 atattgaaat tggtgaatcg gcaatgaagc caacgttgat tcatgacatc atcacagaat
    28561 aaaggaaaaa agcggacttt accgttttaa agaaaagggg aaaagaaatg gaactaaacc
    28621 gaatgatcga ccatactatt ttgaaagcag acgcatctaa agaagctgtg atgcaaatta
    28681 tcgaagaagc aaaaaaatac catttttatt ctgtctgcat caatccagca tgggttgcgc
    28741 tagcgaaaga acaattacaa ggtgagccag tagccgtatg tacagtaatc gggtttcctc
    28801 taggagcaaa cacacccgag acaaaagcat ttgaaacaac agatgccatc aataacggtg
    28861 cagatgaagt cgatatggtc atcaatatcg gtgctttgaa atcaaaggat gatcaacaag
    28921 tccaaaaaga tatcgaagca gttgttgaag cagcaaaaga tcgtgcgctt gtcaaagtta
    28981 ttattgaaac atcgttatta gatagagaag aaatcatccg agcttgcgaa atagcaaaag
    29041 ctgcaggcgc tgattttgtc aaaacatcaa ctggtttctc aacaggcgga gcaaaggtag
    29101 aggatgtccg tttgatgcgt gaaactgtag gaccagaaat gggtgtcaaa gcttccggcg
    29161 gtatccataa cgaagaagaa gcaatggcaa tgatcgaagc tggtgctaca agaatcggaa
    29221 caagcgcagg agtagcaatc gtatctggtt caactggtga aggctattaa ttttttcaaa
    29281 ggagaagctc atggcagaac tcaaacaaga atggatcaac acagctattg aagcgttaga
    29341 taaagcctat gttccttatt cccattttcc ggtaggcgct tgtctcgtaa cggaatcagg
    29401 caagatttat caaggcatca acattgagaa tgcatcattt ggattaacga attgtgccga
    29461 gcgcacagct tttttcaaag cagtatctga aggagaaaaa acatttacgc atctagtcgt
    29521 agcggggcac acccccgatc ctatctctcc ttgtggtgca tgtcgacaag taatggcaga
    29581 attctgttcc cctgatatgc cggttacgct agtaggagac aatggtgtga cgaaggcaac
    29641 gaccgttcgt gcactgctgc cttatgcatt tactgaaaaa gatctataac tcatgttcat
    29701 tcagtcagct gactgttgaa aaataaaaca attattttag gaggctttac agaaatgaaa
    29761 aaagcaaaat tatttggttt aggtgctgtc gcactagcag cagggttatt tttaggtgca
    29821 tgcggcaaca acggctctac tgattcatcc ggtggcaaaa gctcatcaga cacaacaact
    29881 gcagcattga tcacagacac aggtggtgta gacgaccgtt cattcaacca gtcagcttgg
    29941 gaaggactag aaaaatgggg gaaagatcaa ggactttcac gaggaaatga tggcttccaa
    30001 tatttccaat cttcaaatga atcagattac atcccaaata ttgaccaagc attgaatgct
    30061 ggattcaaaa cgatttttgg tattggttat aaactaaaac cagcgatcca agaacaagca
    30121 acaaacaata caggtacgaa ctttgttatt atcgatgatg tcatcgatgg attagataac
    30181 gttgtatctg caactttcaa agacaacgaa gcttcttatc ttgcaggtgt tgcagcagct
    30241 tatacgactg aaacaaacgt agtcggcttt atcggcggtg taaaaggtga agtaatcgat
    30301 cgttttgatg ctggattcaa agccggtgtt gatgcaggtg cgaaagaatt aggaaaagaa
    30361 atcaaagtat tgaatcaata tgctggtgac ttctctgctc cagataaagg acgttcaatt
    30421 gctcaaggta tgtatgcaca aaacgcagat atcatcttcc atgcttcagg cggtacaggt
    30481 aacggtgtat tccaagaagc aaaatcattg aacgaatcag gcgacaaaaa agtttgggtt
    30541 atcggtgttg accgcgacca atcagacgaa ggcgaataca cattaaacgg cgaaaagaaa
    30601 aacttcacat tgacatctac actgaaagca gttggaacag tagtagaaga tttggcacaa
    30661 aaatcagcgg acggtaaatt ccctggcggc gaacacactg tttatggatt gaaagaagac
    30721 ggtgttggtc taacagaagg acaactttct gacgaagcga aaaaagcagt tgatgaagca
    30781 aaagaaaaaa tcatttcagg tgacgtaaaa gttccagaaa ctcctgaaga aaactaaaac
    30841 catttctata gccttgttag acacatgttt gacaaggcta tggtttgatt agaacaagaa
    30901 ttgttcattt atccaagctg ccttgtgaca gtttggataa gggaacaact ccctgaagta
    30961 atgtttgttt caaaagaaga acgctcacta agcgtgaatc ttagtcaatc gttgccctag
    31021 atagaaatcg ttaggatgtg aaaaaaaggt ggttcaagaa aatattgtca tagaaatgca
    31081 gaatattacc aaagaatttg gaacattcaa ggcaaatgac aacatcaatt tacaagtaaa
    31141 ggcaggagaa attcatgcgt tgcttggaga aaacggtgct ggcaaatcta cattgatgaa
    31201 cgtgctttcc ggattattag agccgacatc agggaaaatt ttgatgcgtg ggaaagaagt
    31261 aaagatcaca agtccgacca aagccaacca attagggatt gggatggtcc atcagcactt
    31321 tatgcttgtt gatgccttta ctgtaacaga aaacatcgtg ttgggaagcg agcctagtcg
    31381 cgcagggatg cttgaccata aaaaagcacg aaaagagatc caaaaagttt ctgaacagta
    31441 tggattgtca gtcaacccag atgcttacgt tcgtgatatt tcagttggaa tggaacaacg
    31501 ggtagaaatt ttaaaaacac tttaccgagg agcagatgta ctgatttttg atgagccgac
    31561 agctgtattg acccctcaag aaattgatga attaatcgtg atcatgaagg aattagtcaa
    31621 agaaggcaag tcgatcattt tgattacgca taagttagat gaaatcaaag cagtagctga
    31681 ccgctgtaca gttatccgcc gtggaaaagg aatcggtaca gtcaacgtta aagacgtaac
    31741 ctcacaacaa ttagccgata tgatggttgg aagaacggtt tcattcaaaa cgatgaaaaa
    31801 agaagcgaag cctcaagaag tcgttttgtc tattgaaaat ctagtggtga aagaaaatcg
    31861 tggattagaa gccgtgaaaa acttgaactt agaggttcgt gctggcgaag tacttggtat
    31921 cgctggaatc gatggaaacg ggcagtcgga gttgatccaa gctttgactg gtttgcgaaa
    31981 ggcagaaagc ggacatatca agctaaaagg ggaagacatc actaataaaa aaccccgaaa
    32041 aatcactgaa catggtgtag gacacgtgcc agaagaccgt cataaatacg ggttagtcct
    32101 agatatgaca ttatctgaaa atatcgcact acaaacctat catcaaaaac cttacagtaa
    32161 aaacggcatg ctgaattatt cagtaatgaa tgaacatgcc agagaattga tcgaagaata
    32221 tgatgttcga acaacgaatg aacttgttcc cgcaaaagct ttatcaggcg gaaatcagca
    32281 aaaagcaatt atcgctcgtg aagtcgaccg agatcctgat ctgttgattg ttgcaaatcc
    32341 aactcgtgga ctggatgtag gtgcgatcga atttattcat aaacgtctga tcgaacaaag
    32401 ggacaaatac aaagcagtgt tactgatcag tttcgaatta gaagaaattt taaatgtttc
    32461 ggatcgtatt gctgttatcc atgaaggaga aattgtcggt atcgttgatc cgaaagaaac
    32521 atctgaaaat gaattaggtc tattgatggc gggctatacc ttagaagaag cacgaaaaga
    32581 gttagaaaag ggggctggcg cacatgaatg atcgcagcga aaaattccgt aatttattag
    32641 tgcctgtact ttcagttgtt ttaggattga tcttaggcgc gatattgatg gctgcttttg
    32701 gttttcagcc catccaaggt tattcttcta tgctagatgc agcccttggt tcgcaaagag
    32761 ggataggtga aacgttaagg caagcaacgc cgttgatttt tacagcatta ggtttttctg
    32821 tagctaactc agctgggttt ttcaatattg ggctttctgg acaagcactt tgcgggtgga
    32881 tcgtcagtgt ctgggtggca cttgcgtttc cagatctgcc aaaagttgtt ttgcttccgt
    32941 tatgcgtgat cttaggtgcc ttagctggtg cgatggcagc ggctgttcca ggtttacttc
    33001 gagcattttt tggaacaagt gaagtgatcg taacaatcat gatgaactat atcttattat
    33061 acgtaagcac atttgcttta catgaagtga tgcctgaaag ctatcgctca agtttggact
    33121 cttccaatat gatcagtcaa aatgcctcac tgcggttacc atggttaaca caagcttttg
    33181 gcggctctcg cgtaaactca ggattatttt tagcaatcat cgcgcttatt ttcgtttggc
    33241 tgctgatgaa gaaaacgact ttaggatttg aaatccgttc tgttggattg aatccttttg
    33301 cttctgagta tgcaggaatg agtagtaaac gtacgatcgt tttgtcgatg gtcatttctg
    33361 gcgctttggc agggcttggc ggtgtggttg aaggattagg aacgtatcaa aacttctttg
    33421 ttcaaacgac ttcgctatct attggatttg acggaatggc tgtttccttg cttggttctg
    33481 gatcagcaat cggtattctt ttatcagcga tcttgttcag tattttgaag atcggtggac
    33541 ttggcatgca gacaggagca ggtgttccgt ttgagatcgt caatgtatcg attgctttga
    33601 ttatcttctt tgtcgggatc aacttcctga ttcgtttcgt catggctaaa gtcttccaag
    33661 ggaaaaaaca agaagagatc gttgcgacaa tagaatcgaa accaacgaat caaaaccatg
    33721 aagggggcga actataatgt cgactatcga attaattgcc ttgatcctta cttctacact
    33781 ggtttattca acaccgctaa ttctaacgtc actaggcgga actttttctg aacgaagcgg
    33841 gatcgtaaac gtagggctag agggaatcat ggtcatgggt gcttttagtt ccatcgtttt
    33901 caacttgacg atgagtccat cacttggttc tatgacacca tggatcgcta ttttagtggg
    33961 tggcgtcgta ggtatcctat tttctctgat tcacgcagta gcaacagtca gtttgcgtgc
    34021 tgaccatatt atcagcggga cagtaattaa tctgatggca cctgctttag gtgttttctt
    34081 gatcaaagca tggtatggta aaggtcaaac tgataacatc acgcagaatc tggggtattt
    34141 ttctttccca ggattagcag atattccggt cattggacca attttcttta aaaatacatt
    34201 cttacctgct tattgtgcta ttttgattgc tgtcctagct tgggtgatca tcttcaagac
    34261 gaaattcggc ttgcgcctcc gttcagttgg tgaaaatcct caagctgccg acacattagg
    34321 tatcaatgta tatgctatgc gttattcagg cgtactgatt tctggcttgt taggcggtat
    34381 gggcggtgct gtttttgctc agtcgatttc cggtaacttt tcagctggta cgatcgttgg
    34441 acaagggttc atctccatgg ctgctatgat ctttggtaag tggaatcctt taggggcaat
    34501 gggtgcctca ttgttctttg gttttgctca aagcttgagt atcattggcg cacaattacc
    34561 agttatttct tcgattccgc cagtattgct gcaaattgct ccatatttgc tgacaatcat
    34621 tgtgctggtt gttttcttag ggaaagcttc tggtccaaaa gcaaacggga agaactatat
    34681 caaatcaaaa taatctttta gcgaataaaa agggtgggtt acgggaagtg tttttcgtct
    34741 cgcccttttt gttttaaagg caataaaaat aaaaagaaag aaggaataat catgtttaaa
    34801 cgcgtacatc tgatcgtcat ggattcagta ggaattggag aagcaccaga tgccgataag
    34861 ttcggtgatg ttggttctga tacattagga cacattgcga aagaagcagg attgaacgtt
    34921 ccacatttag agcagcttgg tttaggaacg atccgtcctc ttgaaggtgt ggaatcagtg
    34981 aaagatcatc aaggctatgc gacgaaatta gaagaagttt ctgtagggaa agatacgatg
    35041 acaggccact gggaaatcat gggattgaat atcaaaactc catttcgtgt gtttcctaat
    35101 ggattccctg atgatctgat caaacaaatc gaagaatttt ctggccgtaa agtcgtatgt
    35161 aacaaacctt atagcggaac agctgttatt gacgattacg gtgaacacca aatgaaaaca
    35221 ggcgatttaa ttgtatatac ttctgccgat cctgtccttc agatcgcggc acatgaagaa
    35281 atcattcctt tagaagaatt atatcggatt tgccaattcg ttcgtgatat aacaaaagat
    35341 gatccgtata tgattggccg aatcattgca cgtccgtacg tgggtgaacc aggagacttc
    35401 acacgaacaa gcaatcgcca tgattatgcg ttgaatccat tcggacacac agtccttgat
    35461 tctttgaaag aagcaggaaa ggacgtgatt gctgttggaa agatcaacga tattttcaac
    35521 ggacaaggaa tcactgaatc tgtccgcacg aaaagcaata tggatggcgt tgaccagctg
    35581 ctgaaagtta tgaaaaacga tttttcagga atcagcttta ccaatttagt agattttgat
    35641 gcattatacg gtcatcgtcg ggatgtagtc ggctatgcgc atgcgattga agaatttgac
    35701 ttacgaattc cagaattgct tgaagcgatg gaagaagacg acttgctaat gattacagcc
    35761 gatcacggaa acgatccgac gtttactggt accgatcata cgcgagaata tgtaccgtta
    35821 ttggtttaca gtaaaaaaat gaaagaacaa ggggcattgc ctcaaggata ttattcagat
    35881 atttcagcaa cgattgctga gaactttagt gtttcttcga ctgaaaatgg cgaaagcttc
    35941 ttgaaattat taaaataatc tttttaaata ggagaaagca aatgaccaag ttaagcgaga
    36001 tgttacaaga aacgacccag tttatccttg ataaaggagt aaaagaaatt gattttggtt
    36061 tgattctagg ttcaggatta ggtgaattag cagatgaaat cgaagatgct gtaatgattt
    36121 cttatgatga gatcccgttc tttcctgttt cgacagtagt tgggcatgca ggaaagctag
    36181 tttatgggtc tctggcaggc aagaaagtgt tagccatgca agggagattc cactactatg
    36241 aaggtcattc catgcaaaca gtgacctatc cagtacgtgt gatggccgga ctaggggccc
    36301 attcagtcat tgtgactaat gcatgtggtg gtgtcaacga atcatttgta ccaggagatt
    36361 tgatgctgat taccgatcat atcaatttta ctggtgaaaa tcctttgatc ggtccgaatg
    36421 aagatgcaat gggccctaga tttccagata tgagtcaagc ttatacgcct gactatcaag
    36481 caacagcaaa agcagcagca gaaaaactag gtttggatct taaagaaggc gtatatatgg
    36541 gctattctgg accaacttat gaaacgcctg cggagatccg aatgtctcgg acaataggag
    36601 ccgatgcagt agggatgtcg actgttccag aagtcatcgt agcagctcac agcggattaa
    36661 aagtgttagg aatctcttgt attaccaact tagcagcagg tatgcaagcg aatctgagcc
    36721 atgaagaagt tgtagaaaca actcagagag tcaaacaatc ttttaaagca ttggttaaag
    36781 aaacattgac attattgtaa taggaggaac aataaaatga gtgtgcatat tgaagcgaaa
    36841 gaaggcgaga tcgccgataa gattttactt ccgggagatc ctttgcgagc taaatatatt
    36901 gcggagactt ttttggaaga tccagtttgt tacaatcagg tacgcggtat gttaggcttt
    36961 accggcaaat ataaaggaga acgtatttct gttcaaggaa caggaatggg aatgccatca
    37021 gccaccatct atgcccatga attgatccag tcgtatggtg taaagaaatt gattcgagta
    37081 ggtacatgcg gtgcattgtc aaaagacgtc catgttcgtg atttagtact agcacaaggt
    37141 gcagcgacca gttcttcgat gatcgaaaaa aatttccaag cctttcattt tcctccaatc
    37201 agtgatttca atctattact gaaagcatat gagatagcta aagaaaaggg ctatacggtt
    37261 catgtaggaa atgttctttc ggaagattct ttctacaaag atgatttgac agagacgttc
    37321 caattagctg aacttggcgt tttaggagtg gaaatggaag cagcggctct ttattactta
    37381 ggcgcgaaat accatgtgca gacattaagt ttgatgaccg ttagcgacca tttgatcacc
    37441 ggtgaagaaa caacagctgc agaacgtcaa tctacgttca atgaaatgat cgaagtagga
    37501 ttggaaacag cgatagcaga ataagaagga aatgaaaaag ctgccctgca ttaagtaata
    37561 agaacatcca agcaaaaata gctcctcatg tttttgactt ggctggactt attattgcaa
    37621 atgtaagctt ttgaacaccg tttaccaaga ggttgtgaat ctgccgttta actctgagtc
    37681 acaaggaaca atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg
    37741 agaagttggc aggagaaaac cgtttatacg aaaaaaggga ctgtgacaaa tcgtgtcaca
    37801 gtcccttttt tatagtgttt tttataggta gtatttttta gcaactgtta agtcatcatt
    37861 taattcataa acaagtggtt gacctgttgg aatttcaaga tccatgatgt cttcgtcaga
    37921 gataccttcg atatgtttag ctagggcgcg taatgagtta ccatgtgcag ctactaaaac
    37981 agttttgttg tctagtaatg ctggagcaat ttcatcttgc cagaatggca aagcgcgttc
    38041 taatgtcact ttcaagtttt ctccaccagg aatatcgcgt ttgtctaaca ttgcgtaacg
    38101 acggtcattt gctgcagaac cttcgtcagt ttcttccatt aatggaggaa gagtatcgta
    38161 agaacgacgc cagatgtgca cttgttcgtc gccgtatttt tcagctgttt cttttttgtt
    38221 caaaccttgt aatttaccat agtgacgttc gtttaagcgc catgatttga tttgtggtac
    38281 ccaaagttga tctgaatatt ctaagatcaa gttacatgtt ttgattgcac gagttaaaac
    38341 agaagtgtaa gcaacatcaa attcgattcc agcttctttg attttgcgtc cgccttcttt
    38401 tgcttcttcg attccttctg gtgctagatt tacatcagcc caaccagtaa attggttcaa
    38461 tgcattccat tcactaagac cgtgacgaga aaaaactaat tttggcatgt ttagctctcc
    38521 ttttaagata ggtttatatt tctgaaattt tcagttctgt tttattgtac aattttttgg
    38581 aagagatttc catcgaaaaa ttagataaga ttctatgaga aaacaagtag agaatataaa
    38641 aaaacgaaca gtgcccacgc aactgttcgt ttttaggtat tagatgcata attgctcgat
    38701 ttctttttca ggtaaattga tatatttata acatgttcca actgaaacac cgcattttga
    38761 agaaataaat tggatcgttt cttttttttc ataatagaga cgtcggattt ttttgatcgt
    38821 ttttgcatcg atttttggtc ttccgccgat ttttcctttt ttacgagctt catctaatcc
    38881 aactaatgta cgttctttga tcaatgcgca ctccatgttt gctaggtttt ccattaattg
    38941 gaaatagatt tttcccattt cgcgcgtatc gattccttca tcaagactaa tcaagtgcag
    39001 cccgcgatct ttgaataatt gcgtgagttc tgttaattgc cgcgtagatt tgcctaatcg
    39061 atgaagttgg caaatgacta gtgcatcgcc ttgttgcatg tcagcgatca ctgactccaa
    39121 atgaacagca gtagaatcat tttgttccac ttcatatgtc tcatggaaaa tttcttgaca
    39181 accaaagtca gataattgat caacctgagt tgttaaatca acgtcattta tggttgtgcg
    39241 tgcataacca ataattttca tggtgattcc tttctagcag tgattttcta actggatata
    39301 acagtaaaaa tgtagcataa agtacgtcaa aaagatagtt ttttcgcaaa ttttccgctg
    39361 tcttttttta ttggatgatc aagcagtttt tctttattta cgacggattg cgtcaagaat
    39421 ctcaacgcct ttttctgagc cgacaactac tttagaaacc atgtttagga aaagcccatg
    39481 ttctactacc ccaacaagtt catctaaata ggtagctaag ctttctggct gttcgatgac
    39541 ttctagatgc agatcaatga tgtaatgacc accatctgtg gttaagactt ctccgttttc
    39601 gtctgtacgc aagacgggtt ggaatctttt ttcttcaaaa atatgaagta gctgttggga
    39661 gccataaggg atcacttcaa ctgggagtgg gaacttccca agtttatcga ctaatttaga
    39721 agaatcaacg atccaaatcg tttcttttga gtacgtagcg actattttct cgaaaagcaa
    39781 agcagcgccg ccgcctttga tcccttgaaa atcagcactg atttcatcag caccgtctat
    39841 tgtcaaatcg actacgggga cttcatcaat actctttaac ggtattccta atttttccgc
    39901 ttgttctttt gtcgcatttg aagtagtaac tcctgtgata cgtaaacctt cttcacgcat
    39961 acggcgacca atctcttcta ccatataata ggcggttgaa ccggtcccga gacctacgat
    40021 catcccgtcc tttacgaatt tcgcggcttc aatgccagct aattgtttta aattcatctt
    40081 tgcgtccacc tttttttagt ttgagcatcg tgctttcctc actattttag cgtgatttac
    40141 ggtaaaaaga taccattctt ttttattcca ataaagcttt ttcaaaaaaa attgcatctc
    40201 ttgttgacat gttttttcat tcgtgatatt ctaacaaagg tgctttatct acaggtttct
    40261 gtgaagaaac gtgctgactg tttatcaaag catatttgat aaggatgcag acattgcatt
    40321 tattttttat cacaaaaaaa gaaccacctg gatgtgtgga actagacgca aatcgtggga
    40381 aggaggaaac aaggaatgcc tacaattaac caattagtac gtaaacctcg taaatcaaag
    40441 gtggaaaaat ctaattcacc tgctttgaac aaaggatata acagctttaa gaaaactcaa
    40501 actaacgtaa actcacctca aaaacgtggg gtagcaactc gtgtgggtac aatgacacct
    40561 aaaaaaccga actcagcttt acgtaaatat gcacgtgttc gtttgtcaaa cttaattgaa
    40621 gttactgctt atatcccagg gattggtcat aacttacaag aacacagtgt tgtattatta
    40681 cgcggtggtc gtgtaaaaga cttaccaggg gtacgttacc atatcgttcg cggtgcttta
    40741 gatactgctg gtgttaacga ccgtaaacaa agccgttcta aatacggaac taaaaaacct
    40801 aaagcttaat tttaattatt aaacaaatga aacttgcttc tactatatag aagtaattac
    40861 tatgaacaat atttcggaag gaggagttac ggatgccacg taaaggtcct gttgcaaaac
    40921 gtgatgtttt accagatcct atttataact caaaattagt aactcgcttg atcaaccgtg
    40981 taatggttga cggaaaacgc gggattgcag ctaacattat ctataatgcc tttgacttga
    41041 tcaaagaatc tacaggtaac gatccattag aagtgtttga acaagcaatg aaaaacgttc
    41101 aacctgttct tgaagttaaa gcacgtcgtg ttgggggttc aaactaccaa gtaccagttg
    41161 aagttcgccc tgaacgccgc gttactctag gtcttcgttg ggtagtaaac tacgctcgct
    41221 tgcgcggtga acacacaatg gaagaacgct tagcaaaaga aatcatggat gctgcaaaca
    41281 acacaggtgc ttctgttaaa aaacgtgaag acactcataa aatggctgat gccaaccgtg
    41341 cgtttgctca ctatcgctgg taagattctc tctgtttggt cggcttttat aagtcgacct
    41401 cagatagtgt ccttattttt agcaactaga tagtaaagag aggagaaaca aggagaatga
    41461 ccagagaatt ttctttacaa aacactcgta atatcggtat catggcccac atcgatgctg
    41521 gtaaaacgac tgctactgaa cgtatcttgt actatactgg taaaatccat aaaattggtg
    41581 aaactcatga aggagcttca caaatggact ggatggaaca agaacaagaa cgtggtatta
    41641 cgatcacttc tgctgctact acagcacaat ggaagggtca ccgaatcaac atcatcgaca
    41701 caccaggaca cgtagacttc acagttgaag ttgaacgttc attgcgtgta cttgatggtg
    41761 ctgtaactgt tcttgatgca caatcaggtg ttgaacctca aactgaaaca gtttggcgtc
    41821 aagcaacaac ttatggtgta cctcgtatcg tatttgcaaa caaaatggac aagatcggtg
    41881 ctgacttctt atattcagta tcaactttac atgaccgttt gcaagcaaac gctcacccaa
    41941 tccaattacc aattggtgcg gaagacgact tcacaggaat tatcgacctt gtaacaatga
    42001 aggctgaaat gtatacaaac gatcttggaa cagagatcga agaaacagaa attcctgaag
    42061 aataccgcga attagctgaa gaatggcgcg aaaaattggt tgaagctgta gctgaaactg
    42121 atgaagaact tactttgaaa tacttagaag gtgaagaaat cactgaagct gagttaaaag
    42181 aaggtatccg ccgcgcaaca gttaacgtag aattctaccc agtactatgt ggttcagcat
    42241 ttaagaacaa aggggttcaa ttactattgg acgctgttct tgattacttg ccatcaccgt
    42301 tagatatccc agctatcaaa gggattgacc ctaaaactga tgaagaagta gaacgtcctg
    42361 cagacgacag cgctcctttc tcagctttag catttaaagt tatgactgac ccattcgtag
    42421 gtcgtttaac tttcttccgt gtgtactctg gtgttttaca atcaggttca tacgtacaaa
    42481 acgcaacaaa aggcaaacgt gaacgtgttg gtcgtatcct acagatgcat gccaactctc
    42541 gttcagaaat ctctgaagtt tacgctggag atatcgctgc tgctgttggt ttgaaagaca
    42601 caactactgg ggacacacta tgtgatgaaa agagtctagt tattcttgaa tccatggaat
    42661 tcccagaacc agttatccaa gtcgctattg aacctaaatc aaaagctgac caagataaaa
    42721 tgggtgtggc tttacaaaaa ctatctgaag aagatcctac tttccgtgct gaaacaaacg
    42781 tggaaacagg cgaaacaatc atcgctggta tgggtgaact tcacttagat atcatcgttg
    42841 accgtatgcg tcgtgaattc aaagttgaag ctaacgtagg tgcgcctcaa gtatcttacc
    42901 gtgaaacttt ccgtgctggc actcaagccg aaggtaagtt tgtacgtcag tctggtggta
    42961 aaggtcaata cggtcacgta tggattgaat ttacaccaaa tgaagaaggt gctggtttcg
    43021 aatttgaaaa tgcgatcgtc ggtggggttg ttcctcgtga atacattcca gctgttgaaa
    43081 ctggtttgaa agatgctatg gaaaatggtg tcttagctgg ctatccatta gtagatatca
    43141 aagctaaact ttacgatggt tcataccatg atgtcgattc aaatgaaact gccttccgtg
    43201 ttgctgcttc tatggcatta cgtgcagcag ctaagaaagc taatccagta atccttgaac
    43261 caatcatggc tgtagaagtt gttatccctg aagattattt aggtgatgtt atgggtcacg
    43321 taactgctcg tcgtggacgt gttgaaggta tggaagctcg cgctggcggc caacaagttg
    43381 ttcgtgcgat ggttccactt gctgaaatgt ttggttatgc tacaactctt cgttctgcta
    43441 ctcaaggtcg tggtacattt acaatgacat ttgaccacta cgaagatgta ccaaaatcag
    43501 tacaagaaga aatcattaag aaaaacggcg gaaaagctga ataatttctt gaaaccggat
    43561 agtcctgcaa agagattatc caaagagact atatttttaa tatagtttcg tgtaaaataa
    43621 ttatcgatga tatgggcatg tggtgtacct tgtgtacatc atatacctat cagacaaata
    43681 aaaaatatat tgtattttta ggaggacatt ttaaaatggc aaaagaaaaa tttgaccgtt
    43741 ctaaaccaca cgttaacatt ggtactatcg gacacgttga ccatggtaaa actacattaa
    43801 cagctgcaat cacaactgta ctatctaaga aaaacggcgg ccaagctatg gcttacgatc
    43861 aaatcgatgg tgctccagaa gaacgcgaac gcggaatcac aatctcaaca gctcacgttg
    43921 agtatgaaac agatacacgc cactacgctc acgttgactg cccaggacac gcggattacg
    43981 ttaaaaacat gatcactggt gctgctcaaa tggacggagc tatcttggta gtttctgctg
    44041 ctgacggccc aatgcctcaa actcgtgaac acatcctatt gtctcgtcaa gttggtgttc
    44101 cttacatcgt tgtattcttg aacaaagtag acatggttga tgacgaagaa ttactagaat
    44161 tagttgaaat ggaagttcgt gacctattaa cagaatacga attccctggt gacgatgttc
    44221 ctgtagttgc tggatcagct ttgaaagctc tagaaggcga cgcttcatac gaagaaaaaa
    44281 ttcttgaatt aatggctgca gttgacgaat acatcccaac tccagaacgt gacaacgaca
    44341 aaccattcat gatgccagtt gaagacgtgt tctcaattac tggacgtggt actgttgcta
    44401 caggtcgtgt tgaacgtgga caagttcgcg ttggtgacga agttgaagtt gttggtattg
    44461 ctgaagaaac ttcaaaaaca acagttactg gtgttgaaat gttccgtaaa ttgttagact
    44521 acgctgaagc tggagacaac attggtgctt tactacgtgg tgttgcacgt gaagacatcc
    44581 aacgtggaca agttttagct aaaccaggta caatcacacc tcatacaaaa ttctctgcag
    44641 aagtatacgt gttgacaaaa gaagaaggtg gacgtcatac tccattcttc actaactacc
    44701 gtccacaatt ctacttccgt acaactgacg taacaggtgt tgttgaatta ccagaaggaa
    44761 ctgaaatggt tatgcctggc gacaacgtaa caatggaagt tgaattaatc cacccaatcg
    44821 ctatcgaaaa cggtactaaa ttctcaatcc gtgaaggcgg acgtacagtt ggtgccggtg
    44881 tcgttacaga aatcaaagct taattcactt aagttttaaa gtaaagcaac atttattcgg
    44941 acgtaatcgc tcggaacgaa ggtcttagga tctttgttcc gagctttttt atttattgca
    45001 ggatcaggaa aaaagacagg agtattataa atagaagaaa cacgaaataa aagagtcagt
    45061 attttctaaa tgaaacttta tgaaaacaaa atgtttttta caagaaaaag ccttgctttg
    45121 tgagtttata tatattataa tgacaaaggt gcgtttactt tagtgaattg cacagacgta
    45181 atcagaatga tttcgtcggc taagaaacga gaggttgcga cacgcccgga cgctttgcca
    45241 cgaacgagcg tgacggaaat tttcgtggag ctatgtctac ttttcaaaat aggcgaagga
    45301 gggaacaaga tggcaaaaca aaaaattcgt atccgtttaa aagcgtatga acaccgtatt
    45361 ttagatcaat cagcggataa aatcgtggaa actgcaaaaa gaactggagc tagcgtgtct
    45421 ggtccaattc cattaccaac tgaacgcagt ctttacacaa tcatccgtgc gactcataaa
    45481 tacaaagatt cacgcgaaca attcgaaatg cgtacacaca aacgtcttat cgacattgtg
    45541 aacccaacac caaaaactgt tgatgctttg atgaagctag acttaccatc tggtgtaaac
    45601 atcgaaatca aattataaaa ctaaaacaaa aataatggag gtgtactcat gaccaaagga
    45661 atcttaggga aaaaagtggg aatgacacaa atcttcactg aatctggtga attaattcca
    45721 gtaactgttg tagaagctac tccaaacgta gtactacaag tgaaaacaat ggaaacggat
    45781 ggctacgaag ctattcaagt tggttaccaa gatatgcgtg aagttttatc aaacaaacct
    45841 gcgaaaggtc atgttgcaaa agcaaacacg gctcctaagc gcttcattcg tgaattcaaa
    45901 aatgttgagc taggagaata tgaagtagga aaagaaatta cagtagatgt tttccaagca
    45961 ggagacatta ttgatgtaac aggtactacg aaaggtaaag gattccaagg ggttatcaaa
    46021 cgccacggac aaagccgcgg accaatggct cacggttctc gttaccatcg tcgtcctggg
    46081 tcaatgggtc cagttgcacc taaccgtgta tttaaaaaca aacgtcttgc tggccgtatg
    46141 ggtggcaacc gcgtaactat ccaaaacttg gaagttgtac gtgtcgatgc agaaagaaat
    46201 gttatcttga tcaaaggtaa tgttcctgga gctaaaaaat ctttaattac tatcaaatca
    46261 gctgtgaaag ctaaataatt gtaggaagaa aggaggaact aaggaatgcc gaatgtagca
    46321 ttattcaaac aagatggaag ccaaaacggt gaaatcacac ttaacgaaga aatcttcgga
    46381 attgaaccta atgaaagtgt tgtttacgat gcaatcgtaa tgcaacgtgc gtcattaaga
    46441 caaggaacac acgcggttaa aaaccgtagc gctgttcgcg gcggcggacg taaaccatgg
    46501 cgtcaaaaag gaacaggtcg tgcacgtcaa ggatctatcc gctcaccaca atggcgtgga
    46561 ggtggcgtag tctttggacc aacaccacgt tcttacagct acaaacttcc taaaaaagtt
    46621 cgtcgtttag caatgaaatc tgtattgtca gaaaaagttg ctgaaaacaa cttggtagca
    46681 atcgaaggct tgaacttcga cgcaccaaaa acaaaagaat tcaaacaagt tcttgctaac
    46741 ttatctatcg actctaaagt attggttgtt ctagaaaaag gtaacgactt tgctgcttta
    46801 tcagcacgta acttaccaaa cgtttctgta gtaacttctg ataatgtgag tgtgctagac
    46861 gttgtatcaa atacaaaagt gttagcaaca caaactgctc ttactcaaat tgaggaggtg
    46921 cttgcataat gaacttacta gacgtaatca aacgcccagt gatcactgaa aaatcaatgc
    46981 ttgccatgga tgacaagaaa tacacttttg aagtggacac tcgcgcaaac aaaactttag
    47041 taaaacaagc ggtagaagct gcttttgacg ttaaagtcaa aaacgtgaac atcgtgaacg
    47101 tacgtgcgaa attcaaacgt atgggcaaat atgcaggata tacaaaaaaa cgtcgcaaag
    47161 cgatcgttac attgactgaa gattcaaaag aaatccaatt attcgaagct gctgaataag
    47221 cactaataga taactcatta aattaggagg gaaaaacgtg gcgattaaaa agtacaaacc
    47281 tacctcaaat ggtcgtcgta acatgacagg ttctgatttt gctgaaatca caacatcaac
    47341 acctgaaaaa tcattgttac aaccattgaa aaaccatgct ggacgtaaca acaacggccg
    47401 catcactgta cgtcatcaag gtggcggaca caaacgccaa tatcgcgtga tcgacttcaa
    47461 acgtaacaaa gataacgttg ttgcaactgt tcaaacgatc gaatatgatc caaaccgttc
    47521 agctaacatc gcgttagtac actatgaaga tggagtgaaa gcttacatct tagcacctaa
    47581 aggactagaa gtgggtatga aacttgtttc aggtccagaa gcagatatca aagtcggaaa
    47641 tgctcttcca ttagaaaaca ttccagttgg tactgttatc cacaacattg aaatgaaacc
    47701 tggtaaaggt ggacaattga tccgttctgc tggtacaagt gctcaagtac ttggtaaaga
    47761 aggcaaatac gtattgatcc gcttgaactc tggtgaagtt cgtatgatct tagctgcatg
    47821 ccgtgctaca atcggttctg taggtaacga acaacacgaa ttaatcaaca tcggtaaagc
    47881 tggacgctct cgttggatgc gtaaacgccc aactgtacgt ggtagcgtaa tgaaccctaa
    47941 tgatcaccca cacggtggtg gtgaaggtaa agctcctatc ggacgtaaag caccagtttc
    48001 tccttggggt caaccagctc ttggttacaa aactcgtaac aaaaaagcta aatcagacaa
    48061 acttattgtt cgtcgtcgca aaaataaata attactttga ccatgtgtcg cacattttga
    48121 gaggaggttc accatgggtc gtagtttaaa gaaaggacct tttgtcgatg agcatttaat
    48181 gaaaaaagtt gaagctcaag caggggttga aaagaaaaaa gttatcaaaa cttggtcacg
    48241 ccgttcaaca gttttcccaa gttttgttgg atataccatc gcagtttatg atggacgtaa
    48301 acatgtacca gtttacatcc aagaagacat ggtaggacac aaattaggtg aatttgcacc
    48361 tacaagaact tatcgtggac atgctgctga cgataagaaa acgaaacgct aatttgaggg
    48421 gaggataaat ccaaatggca gaacaaatca catcagctaa agcaactgca aaaacagttc
    48481 gcacttcacc tcgaaaagcc cgtttagtaa ttgaccttat cagaggtaaa agtgtcgcag
    48541 atgcaatttc aatcttgaaa ttcacaccaa acaaatctgc tggaatcatt gaaaaagtat
    48601 tgatgtcagc agttgcgaat gcagaaaata actttgactt agatgttgaa aacttggtag
    48661 taagcgaagc ttttgttaac gaaggaccta caatgaaacg tttccgtcct cgtgcaaaag
    48721 gatcagcttc tccaatcaac aaacgtacaa gtcatatcac ggtagtcgta tcagaaaaat
    48781 aaggagggat aatcagtggg tcaaaaagta catccaattg gaatgcgtgt aggcatcatc
    48841 cgcgactggg atgctaaatg gtatgctgaa aaagagtatg ctgagttctt acacgaagat
    48901 ttaagaatcc gtaaatttat ttcaactaaa cttgctgatg ctgctgtatc aacagttgaa
    48961 atcgaacgcg caacaggtcg cgtaaacatt tcaattcaca cagctaaacc aggtatggtt
    49021 attggtaaag gcggttctga agtcgaaagc ctaagaaaag aattaaacaa attaactggt
    49081 aaaagaatcc atatcaatat cgtggaaatc aaaaaaccag atctagatgc aaaattagta
    49141 ggtgaaggaa tcgcacgtca attagaaaac cgtgttgctt tccgtcgcgc tcaaaaacaa
    49201 gccatccaac gctcaatgcg tgctggcgct caagggatca aaactcaagt atctggtcgt
    49261 ctaaacggag cagatatcgc tcgttcagaa ggatactcag aaggaactgt tcctcttcat
    49321 actttacgtg cggacattga ttacgcatgg gaagaagcag atacaacata cggaaaacta
    49381 ggagttaaag tgtggatcta tcgtggagaa attcttccaa ctaaaaaaaa cactgagaaa
    49441 ggagggaaat aatcatgtta gtacctaaac gtgtaaaaca ccgtcgtgaa ttccgcggaa
    49501 aaatgcgcgg ggaagctaaa ggcggaaaag aagtagcatt cggtgaatac ggtttgcaag
    49561 ctgttgattc acattggatc acaaaccgcc aaatcgaagc tgctcgtatc gcaatgactc
    49621 gttacatgaa acgtggtggg aaagtatgga ttaaaatttt ccctcacaaa tcttatactg
    49681 ccaaagcaat tggggtacgt atgggttctg gtaaaggggc acctgaagga tgggttgcac
    49741 cagtaaaacg tggtaaaatc atgtttgaaa tcgcaggcgt tcctgaagaa gtagctcgtg
    49801 aagcgttacg tctagcttct cacaaattac caatgaaaac taagatcgta aaacgtgagg
    49861 aaatgggtgg tgaatcgaat gaaggttaaa gaaatcagag aattaaccac tgccgaaatg
    49921 cttgatcaag aaaaacaatt aaaagaagaa ttgtttaatc ttagattcca attagcaaca
    49981 ggtcaattag aaaacactgc acgtattaaa gaagtacgta aatcgattgc acgcatcaaa
    50041 actgtgttgc gtgaacaagc taagtaatta tggaaggagg ccattaagcg tatgactgaa
    50101 ggaagaaatc aacgcaaagt ttatcaaggt cgcgtggttt cagacaaaat ggataaaaca
    50161 attaccgttg ctgtcgaaac aaagaaaaac caccctatct atggcaaacg catgaactat
    50221 tctaagaaat acaaagtgca tgatgaaaac aacacagcaa aagttggcga catcgtgaga
    50281 attatggaaa ctcgtccatt atcagctaca aaacgtttcc gtttgttgga agtagtcgaa
    50341 gaagcagtta ttatctaata acacgagatt ttcctatata gattgaatgc aaaatctgaa
    50401 aggaggatac acaacgtgat ccaagcagaa agtcgtttaa aagtcgctga taactcaggc
    50461 gcacgtgaaa ttttgacgat caaagtcctt ggtggatctg gtcgtaaaac tgctaacatc
    50521 ggtgatgtga tcgttgctac ggttaaacaa gcaacgccag gtggggttgt caaaaaaggt
    50581 gacgtcgtta aagccgttat cgttcgaaca aaatcaggag ctcgtcgtac agacggttca
    50641 tatattaaat ttgatgaaaa tgctgcagtg attattcgtg atgataaaag ccctcgtgga
    50701 acacgtatct ttgggccagt tgcacgtgaa ctacgtgaaa acaacttcat gaagatcgtt
    50761 tcactagcac cagaagtttt ataatcttga gacacttatc aaaggaggtg cgaaacagtt
    50821 atgtttgtta aaaaaggcga taaagttaaa gttatcactg gaaaagacaa aaacaaagaa
    50881 ggcgttgtac tagcagcgtt cccgaaaaaa gataaagtta ttgtcgaagg tgtaaatgtc
    50941 gttaaaaaac accaaaaacc ttctcaagct gctcctcaag gtggaattgt tgagatggaa
    51001 gcgccaattc atgtttctaa cgtgatggtg gttgactcta ctggtgtagc tggccgagtt
    51061 ggctacaaag aagtagacgg caaaaaagtc cgtgtttcta aaaaaaccgg tgaagtttta
    51121 gataaataaa agtttaagga aggagggtct tactgaatga accgcctaaa agaaaaatat
    51181 cttaaagaag taactccatc attgatggaa aaatttaact atagctctgt tatgcaaaca
    51241 cctaaagttg aaaaaatcgt catcaacatg ggtgttggtg atgcggtatc aaacgctaaa
    51301 aacttagata aagcagttga agaattaact ttgatcactg gtcaaaaacc aatgattaca
    51361 aaagctaaaa aatcaatcgc tggattccgt ttacgtgaag gaatgccaat tggtgcaaaa
    51421 gttacattgc gcggagaaag aatgtacgaa ttcttagaca aattggtttc tgtttcacta
    51481 ccacgtgtac gtgacttcca tggtgtaagt aaaaaagcct ttgacggtcg tggaaactat
    51541 actttaggta ttaaagaaca attgatcttc ccagaagtag attatgattt agtagataaa
    51601 gtacgtggta tggacatcgt tattgtaaca acagcaaact ctgatgaaga atctcgtgag
    51661 ttgttgacac aattaggcat gccattccaa aaataattaa aggaggcgaa ctacgtggct
    51721 aaaaaatcaa tgattgctaa aaacaaacgt cctgcaaaat tttcaacaca agcttatact
    51781 cgttgcgaac gttgcggacg tccacattca gtttatcgta agttccatct ttgccgtatt
    51841 tgcttccgcg aacttgccta taaaggtcaa attcccggcg tgaagaaagc tagctggtaa
    51901 aaagtaaatt cgcataagaa ggaggtaaaa gatcaatggt catgacagat ccaattgcag
    51961 attttctaac tcgtatccgt aacgcaaaca tggttaaaca tgagtcttta gaagtacctg
    52021 catcaaaaat taaacgtgac atcgctgaaa tcttgaaacg tgaaggtttc gttcgtgatg
    52081 ttgaatacat cgaagatgac aaacaaggcg tgatccgtgt tttcctaaaa tttggtaaaa
    52141 acggcgaacg tgttatcaca aacttaaaac gtatctctaa accaggtttg cgtgcttatg
    52201 tcaaagctga cgaagtacca aaagtattga acggtttagg tatcgcaatc atttcgactt
    52261 ctgaaggtgt tgtcactgat aaagaagctc gtgaaaaaaa tatcggcggc gaagttatcg
    52321 cttacgtatg gtaatcaagt agaatctaca aggaggtgtc tttaagtgag ccgtatcgga
    52381 aataaagtcg ttgttatccc tgaaggagta acagttactc aagacggaaa caacgttaca
    52441 gttaaaggac caaaaggtga attgactcgt actttttcag cagatatcaa aatgaatatc
    52501 gaaggaaacg aagtaacttt cactcgtcca aacgacagta aagaaatgaa aacaattcat
    52561 ggaacaactc gtgcgaactt caacaacatg gttgtaggtg tcagcgaagg tttccaaaaa
    52621 gcgttagaac taatcggggt tgggtaccgt gcacaattac aaggatcaaa acttgtattg
    52681 aacgttggtt actcacatcc agtagaaatc acaccaccag ctggagtaac tgttgaagta
    52741 ccagctaaca cacaagtaat tgttaaaggt gcgaacaaag aagaagttgg cgaattagct
    52801 gcaaacattc gtggaactcg tcctccagaa ccttataaag gtaaaggtat tcgttatgtt
    52861 ggcgaatatg tacgccgtaa agaaggtaaa actggtaaat aatcgtttag aaaaattgca
    52921 tagaagccag cagcaggaaa aaggcatttg gctgaagttt accttcaaaa aaatacattt
    52981 ttacttgtgc cgcagcttct atttttcgaa acgtatttac tgcttgaaat agtagtacaa
    53041 taaaaataaa gaggtgacaa ttgtgattac aaaaccagat aagaacaaaa cacgtcaaaa
    53101 gagacatcgt cgtgtacgta acaatatctc tggtactgct gagcgcccac gcttgaacgt
    53161 ttttcgttct aacaaaaaca tctacgctca aattattgat gacgtagcgg gtgtaacgct
    53221 agcaagtgcc tctaccttgg ataaagaaat ttcaggtgga acaaaaacag aagcagcaca
    53281 agctgtcggt aaactagttg ctgaacgtgc agctgaaaaa ggcattaaag tagtagtctt
    53341 tgaccgtggt ggataccttt accatggccg tgtgcaagct ttagctgaag ctgctcgcga
    53401 aaatggacta gaattttaga agaaggagga ataccattca tggtttatat cgatccaaaa
    53461 catttggaat tagaagaccg cgttgttgca attaaccgtg taacaaaagt tgttaaaggt
    53521 ggacgtcgtc tacgttttgc tgctttagtt gttgtcggtg acaaaaacgg acacgtagga
    53581 tttggtacag gtaaagctca agaagttcct gaagcaatcc gtaaagcaat tgaagatgcg
    53641 aagaaaaact tagttgaagt acctatggtt ggttcaacaa tcccacacga agtaatcggt
    53701 gcttttagtg gtggtagaat cctaatgaaa cctgctgtag aaggttctgg ggttgctgct
    53761 ggtggaccag ttcgtgccgt attagaatta gctggggtag cagatatcac ttctaaatct
    53821 ttaggctcaa atacaccaat caacgttgtt cgcgcaacag ttgaaggttt gaaacaattg
    53881 aaacgtgcag aagaagttgc agaacttcgc ggcaaatcag ttgaagaatt aatcggataa
    53941 ggaggacaac aataatggct gaattaaaag ttactttaaa acgcagtatt atcggacgtc
    54001 ctcaaaacca acgcgataca gttaaagcgt taggtcttac aaagattaac agttcagtgg
    54061 ttaagccttc taatgaagca attaaaggca tgatcaatac tgtttctcac ctagtggacg
    54121 ttgaagaaat ttaatttaga aaaatcataa ctagaacatt aaggaggtgc caaacctatg
    54181 aaacttcatg aattaaaacc tgctgaaggt tcacgccaag tacgtaaccg tgttggtcgt
    54241 ggtacttcat ctggtaacgg aaaaactgcc ggacgcggac aaaaaggaca aaaagctcgt
    54301 tcaggcggcg gtgtgcgttt aggatttgaa gggggacaaa caccattgtt ccgtcgttta
    54361 ccaaaacgag gattcacaaa cgtgaaccgt aaagactatg cagtcattaa tcttgatgta
    54421 ttgaaccgct ttgaagacgg agctgaagta actcctgttg ctttagttga agctggaatc
    54481 gtgaaaaacg aaaaagctgg aatcaaagta ttagctaatg gggaactaaa caagaaatta
    54541 actgtgaaag cagcaaaatt ctctaaagca gctcaagaag caattgaagc ggctggtgga
    54601 tcaatcgagg tgatctaatg tttagactat taaaagatgc ttttaaagta aaagacatta
    54661 gatcgaaaat cctatttact gtatttgtgt tgtttgtatt tcgcctaggt gcacatatta
    54721 ctgtaccagg cgtaaatgct gcttcattgc aaaacctttc ttctttgcca tttttcaaca
    54781 tgttgaactt ggtaagtggt agtgcgatgc aaaacttttc cattttctca atgggggttt
    54841 caccatacat tactgcttct atcgtcattc agcttcttca aatggacatc gtgcctcgat
    54901 ttgttgaatg gtcgaaacaa ggggaagttg gtcgtaaaaa actgaatcaa gcgactcgat
    54961 atctgacatt agtattggca tttatccaat ctgtcggtat cactgctgga ttcaatcaat
    55021 acgctcaatt aggtttcgtg aataatccta acgtagcaac ttacgtaacg atcggtttga
    55081 ttctaacagc cggtacgatg tttgttactt ggctaggaga acagatcaca gaaaaaggta
    55141 tcggaaatgg cgtatcaatg atcatttttg caggtatcat ttctagattg cctgaaagta
    55201 tcagagaaat ttatgaagat tactttataa atattgatcc ttcagacata tggaaatctg
    55261 ctatttttgt ggccatttta ctagtagcgg tcttgttgat cgtgacattc gtaacatttt
    55321 tccaacaagc tgaacgcaag atcccgatcc aatatacgaa acgcgtagct ggcgcgccta
    55381 caagcagcta tctgccgttg aaagtaaatg cagctggagt tattccagtt atctttgcta
    55441 gttcgtttat tgctacgcca aatgctgttt tacaagcatt gagcggtaga ttcggttctg
    55501 aaaactggta caaagtgatg atggagatct ttaactataa tacagcacct ggtgctacga
    55561 tttatacgat tctgatcgtt gccttcactt tcttctacgc ctttgttcaa gtaaaccctg
    55621 agaaattagc ggaaaacttg caaaagcaag gaagttatat accaagcgta cgccctggta
    55681 aggggactga agagtatgtc tcaagattac tgatgcgttt aagtacagtt ggtgcagtct
    55741 tccttggttt agtggcattg cttccaatca ttgctcaaat ggtttgggat cttccacaat
    55801 caatcggatt aggcggtaca agcttactga tcgttatcgg tgtagcttta gaaactgcga
    55861 aacagttaga aggcttaatg ctgaaacgta aatatgttgg attcattgag taagaaagcg
    55921 tgttgaggtt tcccctcaac acacgttctc acacatttat taggagggaa aacaatgaac
    55981 ctcattttaa tggggctgcc aggcgcaggt aaaggaacac aagctgaaaa aatcattgat
    56041 gcttatggta ttccgcacat ctcaacagga gatatgttcc gcgcagcgat gcaaaacgaa
    56101 acagctcttg gcctggaagc aaagtcttat atggataaag gtgcattagt tcctgatgaa
    56161 gtaacaaatg gaatcgtgaa agagcgacta gctgaaccag atacagagaa aggcttctta
    56221 ttagatggct ttccacgtac gctagatcaa gcaaaagctc tggacgcaat gctaaaagat
    56281 ttgaataaaa aaattgatgc tgtcatcgat atccatgttg gtgaagaaat cttggtcgaa
    56341 cgtctagccg gccgatttat ctgcagcaat tgtggagcaa cttaccataa aattttcaac
    56401 cctacaaaag ttgaagacac atgtgatcgt tgcggtgggc atgaattcta tcaaagagaa
    56461 gatgataaac ctgagacggt taaaaatcgt ctggctatca acatcaaaaa tagtgaacca
    56521 atcttggctt attataaaga acaaggtttg ctaaacacta ttgatggtgc tcgtgaaatc
    56581 gatgctgtat ttgcagatgt acaaaaaatc attgaaaaat agcacgattg cccgtagccg
    56641 acttgcatta tgcagttact cttgtcaagt tcaataaatt atgatagaat atgtcagtcc
    56701 gacttctaga gaatcctcta gatgatccat tttgagaatt ttgaggtggg aactgcagtt
    56761 tccgccattt tatcgtgtga aaatgcgaaa caagtacaag gaggtactgt gcgtggcaaa
    56821 agaagatatg attgaagtcg aaggtacagt cgtcgaaact ttgccgaatg caatgtttaa
    56881 agttgaacta gaaaacggac accaagttct tgctactgtt tcaggtaaaa ttcgtatgca
    56941 ttacatccgt atcttacctg gtgacaaagt aacggttgaa ttgtctccat acgatcttaa
    57001 ccgtggccgt attacttatc gctttaaata attgtactcc gtaaaactac aggaggtatt
    57061 atcatgaaag taagaccatc agtaaaacca atgtgcgaac attgtaaagt aattcgtcgt
    57121 aaaggacgcg ttatggtgat ttgcccagca aatccaaaac ataaacaacg tcaaggataa
    57181 ttggaggtgc tataaatatg gctcgtattg caggagtaga tattcctcgt gataaacgtg
    57241 tagtagtttc acttacttat atctatggta ttggtaacac tactgctaaa aagatcttag
    57301 ctgatgctgg tgtatctgaa gatgttcgcg ttcgtgaatt aacgaatgaa caaacagatg
    57361 ctatccgtgc agaagtagat aaattaaaag ttgaagggga tcttcgtcgt gaagtgaact
    57421 tgaacatcaa acgtttgatg gaaatcggtt cttaccgtgg aatccgtcat cgccgtggat
    57481 tgcctgttcg tggacaaaac acgaaaaaca atgcacgtac tcgtaaaggc ccagctcgcg
    57541 ctatcgctgg caagaaaaaa taattcttaa gtgaaggagg ttaaaacttc atggcagcaa
    57601 aaaaagtgaa tcgtaaacgc cgtgtgaaga agaatataga agcaggtatt gcacatatcc
    57661 attctacatt caataacact atcatcatga tcactgatac tcacggaaat gcattagcgt
    57721 ggtcatcagc tggttcatta ggtttcaaag gaagcaaaaa atcaactcct tttgccgctc
    57781 aaatggcagc agaaactgct acaaaagcag caatggaaca cggattaaag actgttgaag
    57841 taacagttaa aggacctggt tctggacgtg aagcagcaat tcgttcatta caagctacag
    57901 gtttagaagt gactgcaatt cgtgacgtga ctccagttcc tcataatggt gcccgccctc
    57961 caaaacgccg tcgtgtttaa tgagtgccgc tcattttgag ttttatcagt aacgtcattg
    58021 aacaagacac ttttcgtttt gaaaggggta aagataagaa tgattgagtt cgaaaaacca
    58081 agaatcgcaa aaattgatga agaaaaagat tatggcaagt tcatcgttga acctcttgaa
    58141 agagggtatg ggactacttt agggaattcc ctacgtcgta ttttattatc ttctttgcca
    58201 ggtgctgcca tcactaatat tcaaatcgat ggtgtactgc atgaattctc taccatcaaa
    58261 ggtgttagag aagacgtcac tcaaatcatc ttgaacatta aaggcttagc gctgaaaatg
    58321 tatggccaag aagaaaaaac ccttgaaatc gatattaccg gacctgctac agtaactgct
    58381 ggcgatatta tcgttgatag tgatgtagaa attcttaaca aagatatgta catctgtagt
    58441 gtctctgaag gagctacgtt ccatgctcgc ttaacagtga aacctggacg tggttatgtt
    58501 caagcagatg aaaataaaaa agaagatatg ccaattggcg ttcttccagt cgattcaatc
    58561 tacacacctg ttcgtcgtgt gaactatcaa gttgagaaca cacgtgttgg acaccgtgaa
    58621 gattttgata aattgacgat ggagatttgg acagatggtt caattgaacc gttggaagca
    58681 atgagtttgt ctgcgaaaat catgactgaa catttggata tttttgtgaa cttaactgat
    58741 gaagcaaaaa atgctgaaat catggtcgaa aaagaagaaa cacaaaaaga aaaaatgttg
    58801 gaaatgacga tcgaagagtt agacttgtct gttcgctctt acaattgttt gaaacgtgca
    58861 ggaatcaata ctgtacaaga acttacaaat aaatctgagc ctgaaatgat caaagtccgt
    58921 aacttaggac gtaaatcatt agaagaagtt aaagcaaaat tgcacgactt aggtttaggt
    58981 ttacgtaaag aagattaaaa ccttttacga aggagggaaa ccaacgtgag ttatcgtaaa
    59041 ctaggacgca catctagcca acgtaaagcg atgttgcgtg atttaacaac tgatttatta
    59101 atcaacgaac gtattgtgac tactgaagct cgtgcgaaag aagttcgctc aactgcagaa
    59161 aaaatgatca ctttaggtaa acgcggagat ttgcatgcac gtcgtcaagc tgcggctttc
    59221 gtacgtaatg aagttgccag cgtgcgtgaa gaaaatgagg acatcgtcat tgaatcagct
    59281 ttacaaaaac tgttcaacga tattgcacct cgttacgcag aacgtcaagg cggatacaca
    59341 cgcattttga agacagaacc aagacgcggt gatggtgcac caatggttgt cttagaactt
    59401 gtctaaaatc acactaataa catcacttta tagatgattc ttttagagtg ttatgatgtt
    59461 ggaagatatt tttccgagtc tagctcagcg ctgctcctca agcgaatatc gcttggggag
    59521 taagcactca tcataaagtg tttttttata ccttcaatta cctgtcatga cagatatgtt
    59581 tgaaggcata aaaaaacatt ttaagcgaga aataattgaa aattttgtct ttttttgata
    59641 gtgttagtag gaactttagg atgaagaagg agtaatcatg gagccaatta ttgaattaga
    59701 aaagataaat tataaatacc agccagatga tcttcgcccc gcattgaaag atgtctcctt
    59761 tacaattgat aaaggtgagt ggatcgctat tattggacac aatggttcag gaaaatcgac
    59821 acttgccaaa acgatcaatg gattgcttct gccagaatca gggatcgtga aagtgggaaa
    59881 tcaaatattg gatgaagaaa atatttggac gatccgacag atggttggaa tggtttttca
    59941 aaatccagac aatcagtttg ttggttcgac agtagaagat gacgttgctt ttggtcttga
    60001 aaatcaaggg attcccagag aagaaatgct agtgcgtgtg aaagatgcac ttgagaaagt
    60061 tagaatggct gagtttgctt cacgcgagcc tgctcgttta tcaggagggc aaaaacaacg
    60121 tgttgccatt gccggcgtgg ttgccttacg acctgatatc attattttag atgaagcaac
    60181 cagtatgcta gatccagaag gtcgtgaaga agtgatctct acgatcaaga agatcaaaga
    60241 agaaagtcaa ttgaccgtta tatctatcac tcatgatatt gatgaagcag ctaatgccaa
    60301 tcggatacta gtgatgagac aaggcgaact tgtccgtgaa ggtacaccaa aagaaatttt
    60361 ttctgctggt cctgaactga tcgacttagg tctagatcta ccatttcctg aaaaactgaa
    60421 gagcgcactg aaagaacgtg gggttgatgt gcccagtgaa tatatgacag aagaaaggat
    60481 ggtggattgg ttatggacat ccgttttgaa caagtagact tcacttatca gccgaataca
    60541 ccatttgaac aaagagcctt atttgacatc aatatgacga tcaaagaaaa cagttatact
    60601 gcattagtag ggcataccgg aagcgggaaa tcaaccttac ttcagcattt gaatgcgctt
    60661 gttaagccaa caagcggtac agtccatatt ggagaacgag atattcagcc ggatacggat
    60721 aataagaatt taaagcccat ccgaaaaaaa gttggcatcg tctttcagtt tccagaagca
    60781 cagctattcg aagaaacggt agcaaaagac attgctttcg gtcctaaaaa ctttggtgtc
    60841 agcgaagaag aagcactagt cctagcaaaa gaaacattag aacaagttgg gctggatgaa
    60901 agctatttgg aacgttcgcc atttgaactt tcaggagggc aaatgcgtag agtagcaatc
    60961 gctggtgtgc ttgccatgag gccggaagta cttgtattgg atgaaccaac ggcaggactt
    61021 gatccccagg gcagaaaaga aatgatggag atgttttggc gtcttcataa ggaacagcag
    61081 atcactattg tattagttac gcatttaatg gatgatgtag ccaattttgc agattatgtc
    61141 tatgtgttgg aaaagggacg aatcgttaat agcggggagc cgcaagaggt ctttcaaaac
    61201 attgaatggc taaaagaaaa acaactaggc gtacctactg ccaccgagtt tgcagaagaa
    61261 ttaatggcta aagggatgaa ctttgctacc ttgcctttga cagctgaaga attagcagac
    61321 gctatcgtcc attatgctgg aggaaatgcc catgatgaat aaattgatat ttggtcgtta
    61381 tatgcctgga gattccttga tccatcgatt ggatccccga gctaaattat tagccagttt
    61441 ttattttatc ggaatcattt ttttagcaaa taattgggaa acgtaccttt tgttggcatt
    61501 tttcacatta ctttctgtct tcttgtcaaa agtagatttg aaatttttta tccgaggcat
    61561 tcgcccattg atctggctaa tcctcttcac tgtagctttg caggtcttgt ttacaagtgg
    61621 cggagaaact tattggagtt ggggtgtttt ccatatcact gaatttggtg tgatgaacgg
    61681 cctctttatt ttctgtcgat tcgtgttgat catttttatg tcgactctac tcacgcttac
    61741 tacaccgcct ttggaattat cggatgcgat tgagtacttg cttcgtccat tgaaagccgt
    61801 acggttccca gtccacgaaa tttcattgat gctgtcgatt gctcttcgtt ttgtgcctac
    61861 attgatggac gaaacagaaa agatcatgaa cgctcagcgc gctcgcggtg ttgattttgg
    61921 tgaaggaaac ctagttcaga aaatgaaagc agtcattcct ttgctgattc ctttatttgt
    61981 cagcagcttc aaccgtgcgg aagatcttgc gactgctatg gaagcaagag gctacaaagg
    62041 tggggaagga agaacgaaat atcgtgtatt gcattggcat aatagagaca cgatggttat
    62101 cattgctttt gtattattaa ctgtgctact gatcttttta agaggataaa cgttcagtgg
    62161 gccgctatct attcttttct tgctgatctg tttgcaagaa aggatgcaag cagtgtatga
    62221 caagaaatat tagggtctgt ggcagactaa ggtcacaggc ctctttcttt tatctgaaaa
    62281 gaaagaacga aaaaatttta tagaaaaatc attattccag ataacctttt aggaacaaag
    62341 gagagaaaaa catggtacgt tacaaagcaa tcattgcgta cgacggaaca aattttaatg
    62401 gattccaaaa acagccaaat gggcgtactg ttcaagaaga agtagaaaaa acattacaaa
    62461 aaatggcaaa tggaaaagaa atcacggtct ttggttcggg aaggacagat gccggagtac
    62521 atgcgatcgg gcaagtaatc cattttgatt atccagagga gcgtccgtta gaacgaatgc
    62581 gtttcgcgct agatacccag tcaccagagg atattgctgt aagacaagta gaaattgttt
    62641 cagaagactt ccacgcaaga tatttggtca aagaaaagac gtatcaattt cgagtggata
    62701 tagggaaacc acgcagtcct tttcgacgcc attatgcaag ttattttcct tacccacttg
    62761 atttggaaaa aattcagcgg gcgcttcctg atttattagg gactcacgat ttcacctctt
    62821 tttgtgcatc aggaagctcg atagaggata aaatacgtac gatctacgag gctaagatgg
    62881 aggtaaatga aacaaaagac gaattgttgt ttacatttag gggaaatggc ttcttgtata
    62941 agatgatacg gatcttagta ggaacgcttt tgaaaattgg caatggccga ttgcctgaag
    63001 atagtatccc agatattatt gcgaaaaaag atcgtaatgc agcaggacct acagcacacc
    63061 ctgaaggact ttatttgtat gaagtgaaat atgaataaga ggttatgata gaagtggtca
    63121 gcttcaagaa ataagaaggt atttacgaaa attacttctc aaaattttgc aaaatttcgg
    63181 cttattttcg aagaagctac ttctggaaca ccgtttaagg aagaggtcgt gaaatcagcg
    63241 ttttgacctg agtattagag aaacaaacgg gaaaatagct cctcatattt tgccgtttgt
    63301 tgagctaata ccgaaggtca gctgattgaa caccgtttaa gaaagaggtc gtgagcctgt
    63361 catttaactc tgagtcacaa agagcaattt caaaaaacag cttctcatct ttgatgaata
    63421 tcgtgacttg tggacgaggc gttgataagt gaatcatctt tttgttacct attttttctg
    63481 taaccaaaaa acgatggaac gttgttttga ttgcccttgg tgcggacagt ctgaacaggt
    63541 tccatcgttt ctttattttc tacgtcttct tctgtgtgtg tttcgtggtt gttcttctat
    63601 tgctggatca atcgtgccat aaaaggggcg attgcggtca aggtaccaga cataaagaat
    63661 aaacaatgca atacatagga caaaaaggat tgcacctatc gtaaatcctt caggcaagta
    63721 actgaaagtg acagtatgtt tacctgctgg aacttttatc atcaagaatg cgtctttgaa
    63781 attgctgacc ttgactggtt tcccatcaat tttagctttc catcctttgt cataaggaat
    63841 agttgtcacc aacatggaat cttcagcggt atttacagtc ccagaagctt ttctgccagt
    63901 ggcttccatt tcgacacctt tttctttgat ctgattcatt gcggcttgat aggctacaac
    63961 atctagacca acgactttag gctccatgaa acttatttct ttcgtcccat aaaaacttgc
    64021 agtaaatgtc actgttgtct cttgaggata atagccaaga tcatagtatt gaccagaaat
    64081 gttgatttgc gtttttcgcg atgtaccatt gacagtgatc gtcgcactag aactttctaa
    64141 ttgcgcaaaa ttggttggga acaaacttaa gtaagcttgt gtatttgcag gcacatggac
    64201 ttcccaagtg agctcttttg gctggttatc tgctgtttct gagtaagtga cgccagtcgt
    64261 tgtctttgtg atcgtcgtat tcaactgatt cttcaaagta ggtgtataga atgtaaaata
    64321 ctgttcattt agaccagaca atgtattgat caagtttgtc tgactggtca aattatctgt
    64381 cactggctgc tcaacatcat taacggacaa cggtgcagta aatgctagtg gcaatgcatt
    64441 gacattctga tacagtgtat agtcgccgct ttgaccagct tggcggaagc catatttact
    64501 gaacgtgctt tcgtttttag aaatgttata tttgattcct gtaaacccat ccatcagcaa
    64561 agtattattg ttataacgga tattcaaatt tgtccctctt gaacggaaac ctaatttatc
    64621 caggtaagag gaagaattac gatttcttat agaagaaaac aaactgatac cactgtaacc
    64681 atagttgatc gaatcgtttg cagatactgg atccagattt tccaagcggt aaaacgagtc
    64741 ggaatctttt tttgtttcat ttacaagagc tttcaagtca ggataaggat cagtatataa
    64801 actgcgggaa gcataattcc aatcatcaag aatgccatgg atcatactgt tcgtattgac
    64861 cagtgcttca gcagacatga tcaataataa caatatactc agatgattga atgaaagttt
    64921 tttatgctga taaaatccca cagcaaaagc ataaatccct aagaaaacca ctgtcaatac
    64981 aaaggaagtc atcgtcacat aggtgtagct tccttcaggt ttgatgcccc atgccaccgc
    65041 aaagagagca gctacgacca aaatgattcc taacaacagc ccacgatcgt cttgttctat
    65101 cttttcccat ccttttcctg caagcaggag cactaagaaa gagaacagat aggcataacg
    65161 gaataaaaac atattcggtg catgcatacc atgccagaac aaattcaatg gaacaagata
    65221 aaaacttgcg ataagtatgg cgaaaagact gccgtacaaa aatttatttt tcaacggtac
    65281 tttccgactg gcaaaataaa acagacagag gactaatggt agcagacctg cgtaaacgaa
    65341 cggaatcgat ccgtattttg tcgtgtcata aacaccaatc atatttttca tgattagatc
    65401 cagataagaa gtcgcttctg ttttcaacgt agtgatctga ctcagtgcct cgccatttga
    65461 ccgaagatcc agcactgctg gcaatacaat gatcattgaa gcgccgcctg ccagtaaaga
    65521 agtgatacca taaggaacaa tcgttttttt atattctgac cagtttgtca atagacgggc
    65581 gataaaatat aagaaagaaa atacgccaat cataaaaccc atataaaaac tggataaaaa
    65641 caagagtaaa taactgataa ataaaagttt cggccgttta agatccataa cacgatgaat
    65701 ccccaaaatc actaatggaa gataaaaaaa tgcatccagc cacatgatga tctccgaatg
    65761 tgcagtgata aatgagatca atgcgtaact gacgctaagt gcaacatgcc cccagcgagg
    65821 aatcttgaac gtacgtgcaa gaaaccaaaa agccaatccg gcacagccga ccttaagcaa
    65881 agtcagaaca tacagtgcat ctggcatcat ctggtttgga aaaaagaaca ccagtggcgt
    65941 gaagatcccg cctagatagt aagaaattaa agataaataa ttcaatccta gagaagcatt
    66001 ccatgtataa aaaatacttt gctttccaag aagaacattt cggaagctgg catgaaaatt
    66061 agaaaactgt gaaaaggcat cacttgccaa aatacttctg ctgcttccag gatagattcc
    66121 gatacttaga taaacaagtg ctaaaatcaa aaacggaatc aggaaactag ctgctgcgta
    66181 gcgtccgttt tctctaaaga atgactttaa attttttttc atatttattt tccaccaaat
    66241 ttctatgaag ttgtattcag tttatcatat ccttgttttt ctctgcttaa aaagagtcta
    66301 gttttcacaa aaaaataaaa tttagaataa ataacttcat aatttgttcg tataacaaaa
    66361 ataaacgcaa aaaaagggta ggaatcaaaa gtcccaccct taaaaatttt tattaaataa
    66421 aaaaccgttc actatctgaa cggtccaagt atcattcaat taaacgcgtt caacttttcc
    66481 tgatttcaaa gcacgagttg acacccaaac ttttttaggt tttccgtcga ccataacgcg
    66541 aactttttgt aagttaggtt taacagtacg ttttgttgag ttcatagcgt gtgaacggtt
    66601 gtttccactt tttgtcttgc gacctgtaaa gtaacaaact tttgccatgg taatttcctc
    66661 ctttgccttg atttggagca atagaataat tcagctcata ccagactaac atatcatata
    66721 gaatgggaat ttgcaagtac attttcatag atacaattga caattgagaa gaataattgt
    66781 aaattaaaca aggttatacc tgaaattttg caaggttttt gagtactttg ggtaactgcc
    66841 ttttatttca agttgcgcta tgataaaata tgatagaaga aaaatgggag ttttttaccc
    66901 gttaaggagg ctcattcatg gctgtaaaaa ttcaaacgtc agctggaacc attgaaatta
    66961 ccaatgatgt aattgcaaca gttgttggtg gcgccgcgac agatgtgttc ggtgttgtag
    67021 gaatggccag caaaaatcaa attaaagata atattactga gattttgcgt aaagaaaatt
    67081 actcaagagg agtagttgtc cgccaagaag ataatggtat tgctgtagat gtttatacga
    67141 ttatcagcta tggtacgaaa atctctgaag tttcccgcaa cgtccaagaa aaagtgaaat
    67201 acaatctaga ggcattatta ggcgtaactg ccaattcagt taatgtcttt gtacaaggtg
    67261 ttcgtgtact gccagactag gcaggagact ggctggtaac tcagcagtcg atctgaagga
    67321 ggattatcta ggtgagtgta acagaaataa gtgcaagcca gttccaggaa atggtccagg
    67381 caggtgcgaa tcgtctgcaa gtaaatgcag aatacgtcaa ttcattaaat gtattccctg
    67441 tgccagatgg cgatacggga acaaatatga atctatctat gactagtgga gctaaggcag
    67501 tagtagattc aacctcagaa aaagtaggag aattagcagc aatgctttca aaaggattgc
    67561 tgatgggtgc gcgcggaaat tccggcgtta ttttgtctca attgtttcgt ggattttcta
    67621 agcaaattcc agatgttgtc tcattaaatg cttctgatct tgctgcagcc ttcactcatg
    67681 gagttgaaac tgcgtataaa gcagtaatga aaccagtaga aggaacgatt ttgacagtag
    67741 ctagagaagc agcgaaagct ggagaaaaga aagcaaaaag tactgatgat gtcgttgaag
    67801 taatgacagc tgttgtaaaa ggagcaaagc gtgctttagc taaaactcca gacttgcttc
    67861 cagtcctaaa agaagtcggt gtcgtagaca gtggagggca aggactgctg tttgtttatg
    67921 agggcttttt aagtgcattg aatggagaat tccaagcgga tgaaacatat gaaccttctc
    67981 cagcagaaat ggatgatatg gtcaatgcag aacatcatcg cagtgtccaa ggtcaaatgg
    68041 cgacagaaga tatccatttt ggttactgta cagaaatcat ggtaaaaatc ggagaaggac
    68101 ctacagtcga tagtacattc gattacgaag aattccgtaa ctatttagat ggtataggag
    68161 attctttact tgtggtcaat gatgacgaga tcatcaaagt ccacgtgcat acagaaaacc
    68221 caggagaagt cttgaattat ggacaaaaat tcggttcatt agtcaaaatc aaagtcgaca
    68281 acatgcgctt gcagcatgag acgattttgg aacacgatga agaagtgaac gagtttgcga
    68341 aaaaagaaat accacgtatc ccgtatggta tcgtagcgat cgctgctggt aaaggcgtcc
    68401 aagagctgtt tgaaagttta ggcgctaatt atgttatcag tggtggacaa acaatgaatc
    68461 caagtacgga agacattgtt aaagcgattc aagaagtaaa cgcagataaa gtgattgtct
    68521 tgccaaacaa taagaacatc ttcatggcag ctgatcaagc agcagaagta gcagatatcc
    68581 cagtagcagt tgttccttca agaacgattt cccaaggatt gacagctatg ctttcattca
    68641 atgatcaagc ttctttagaa gaaaacaaag aaacgatgac agaaatgttg tctagcgttg
    68701 tgagcggtca agtcactcac gcgatcagag atacctcaat tgacggtgta gagatcaaag
    68761 aaggagactt tttgggcatg atcgatggaa aaatcctgat ctctaaccca gatatcacag
    68821 caacagcgtt aagtacacta gaacaaatga tcaatgagga cacagagatc gtaacgatct
    68881 tggcaggtga tgaaggaaca gttgaacaag caaatgaatt tgctgagaaa ctaacagaaa
    68941 aacatcctga tttggaaatc gagatccacc aaggagatca gcctgtctat ccttatctat
    69001 tttctgctga ataatttctg tgtcagaata tctttctaac acagtattca ttcataaaag
    69061 gccttcggtt agtgatcagg tatgatcgct gaccaagtcc tttttttgtt aaaggaggga
    69121 ggaaaaattt atgcgttctt tagatgatcc aatcactatg ctggcaggag tcggagaaaa
    69181 aagagcagct agtcttgcca gcttgggcat ccaaacgatt gaagacttac tgacttatta
    69241 tccttttcgc tacgaagata ttcaggaaag aaatctaaac gagatccagg atcaagaaaa
    69301 ggttactttg aaaggaatcg tagtctcgcc tcctgtgatg aatcgatttg gttataaaaa
    69361 aagccgattg caatttcgta tgatgcaaga acatgatgtg ttcaacgttt ctttttttaa
    69421 tcaaccttat ctaaaagaaa aagtcatttt atcggaggaa atcgccgtat acggtaaatg
    69481 ggatgcaaag cgtaaagcct tgaacgggat gaagatttta ggttctcaaa caatggatga
    69541 cttttcgccg atatatcacg tcaacaaatc aattcgtcaa acgacattag ttgatctaat
    69601 caaaaaaggg tttcaagaat acggcacatt gattgaagaa aatctgccaa acaaccttgt
    69661 ggagaaatat cgactgcttg accgagcttc tgctgtaaga agtatgcatt ttccaaaaga
    69721 ccacgaagaa aaccatcaag ccaaacgacg tgtcgttttt gaagagttct ttttatttca
    69781 aatgcgtctt caaggattga aaaaagcaga aaaagcagaa acgaatggtt tggagatcct
    69841 ttatgatgtc caaaaattga aacaatttac tcaaaagcta ccttttgaac tgacaaatgc
    69901 acaaaaacgt gtaacgaatg aaatctgtcg ggatcttcgc agtccgcagc atatgcagcg
    69961 acttttgcag ggagatgtag gtagcggaaa aacagtggtt gccgcgattg cgttatacgc
    70021 taccgttaca gcaggtttcc aaggtgcgtt gatggtgcct acagaaatct tggcacaaca
    70081 acatatggaa agcttgcaac agctgtttga tcccaatgaa gtaaccatcg cattgattac
    70141 ggggtcaacg aaagcaaaag aacgacgtga gctccttgaa aaactagagc aaggggaaat
    70201 taacgtcgtg atcggcacac atgcattgat ccaagatgga gtcgaatttc agaatttagg
    70261 tctagttatt acggatgagc agcaccgttt tggcgtgaac cagcggaaag tacttcgtga
    70321 aaaaggctgg cgaccagatg tcttatttat gacagcgact ccgattccta gaacattagc
    70381 tattacagca tatggtgaga tggatgtatc tatcattgat gaacttccag ctggacgtat
    70441 cccgatcgaa acacgctggg taagaacacc tcaattggac agtgtactgg attggacgaa
    70501 aaaagaactg gcaagaggac atcaaatgta tgtcatctgt ccgctgattg aagaatcaga
    70561 agcattagat gtaaaaaatg cagtggaaat ctatgaaaaa cttcgtgaac tatttgcacc
    70621 aaaatatgaa gttggcttgt tacatggtaa aatgaagaat caggaaaaag aagtaatcat
    70681 ggaagccttc aaagacaacc agatgcagat attagtttcg actactgtaa ttgaagtagg
    70741 ggtaaacgtg ccgaacgcga ccgtcatgct gatcatggat gcggatcgat ttggattggc
    70801 acagctgcac caacttcgtg gacgtgttgg acgcggaagt gatgcttcct actgtatctt
    70861 agttgctaat cctaaaaatg aactaggtgt ggaacggatg aaaatcatga cagagaccac
    70921 caatggtttt gtactaagcg aaaaagatct ggaattacgt ggtcctggtg aagtatttgg
    70981 cttccgtcaa tctggtctgc ctcaatttgc gattgctgac ttggtgacgg atggaaatgt
    71041 tttggaggta gccagagaag aggctgcagc cctttggcaa ataaaggatt ggcagatgct
    71101 tcctgagtat cagcctttag cgcaaagcct ccaaatagaa aatcaggata atcgttattt
    71161 cgattagcag actgtgctat actttatact gatgacggaa aaaggagtgg aaacaatgaa
    71221 aattgccgta gatgcaatgg gcggagatca cgcacctcaa gcaattgtag aaggcgtggc
    71281 tttagcgcag caagattttc cagaagtaga attcttactt tacggaaaag aagcagaaat
    71341 caagaaatac ttaacaaatg aaaaaaacat cacgattatc catacagacg aaaaaatcaa
    71401 tagtgatgat gagccagtaa aagcaattcg acgaaaaaag actgcatcaa tggtccttgc
    71461 tgcacaagca gtgaaaaacg gtgaagcaga tgctgtattt tcagcaggga atacaggcgc
    71521 gctactagca gcagggttgt tcatcgtagg acgtatcaaa aatatcgaac gccctggctt
    71581 gatgtctacc ttgccagtag tagggaaaga aggtgccggt ttcgatatgc tggatcttgg
    71641 cgctaacgca gaaaacaaac cagaacattt gttgcaatac ggtattttag gttcttttta
    71701 tgcacgtaaa gtccgaggta tcggacgtcc tcgtgtcgca ctcttaaaca acggaacaga
    71761 agcaacaaaa ggtagtgaag tgacgaaaaa agcctatgaa ctccttcaga atgaaacaag
    71821 cttgaatttt attggaaacg tagaagctcg tgagctactc aatggtgtgg ctgatgtagt
    71881 ggtcacagat ggatttacag gcaacgctgt tttgaaatct attgaaggaa cagcaatgaa
    71941 tatgatgaat ctattaaaat ctgctattct aaatgaaggg atcaaaggaa aaatgggcgc
    72001 tatgctttta aaagacggct tacgttcttt gaaagcagaa atggattatt ccaaacatgg
    72061 cggtgccgtt ttgtttggct tgaaagcacc agtcattaaa actcatggag caacaggccc
    72121 cgatgctgtt cgctatacga tccgccaaat ccacacaatg cttgagacag atgtagttgg
    72181 acaattagtc gaacaatttg aaaaaagcga agaatagtat ttggatatct gaagcgatcc
    72241 gttccattga aaaaaaggtg gacattcctg aaaaatgcca gtaaaattag ccatggtgta
    72301 ggtaattgac aagtgtatga ttcttggagg tgaaaaagtt gactcgcgaa gaagtattta
    72361 acaaagtagc gaaaattatt tcaaatcatt ttgagataga taccgataaa gtgacggatg
    72421 aattgaacat caaagatgat ttaaaagctg attcaattag tattatggaa ttcgttttag
    72481 agcttgaaga tgaattcggt acggaaattt cagatgaaga cgctgaacaa attgaaacag
    72541 tcggtggcgc agtagattat atcagcagcc atcttaaata atttcaaata aaagcaaaga
    72601 aggataaaaa gctgcatgca gctttttatc cttctttttt taatcttttt gacacgtaaa
    72661 agtcattttt ctgataattc tggcgataaa cagaaattat gttgcaaagt aaagcggttt
    72721 tctatataat tattaataat tcattacaca aagataagaa taacctttgt tataaaacga
    72781 tttattctgt gtaatgtcct tttttattaa gaaaaacttc catttaggaa gcagagaggg
    72841 gtattcgatt gtccgataac caattattag aagttcagaa cctacataca ggattccgac
    72901 tcaaagatga ctattacgat gcagtagatg acgtttcatt tactttagac aaaaacgaga
    72961 ttttagcaat cgttggggaa tctgggtgcg ggaaaagtac cttggctact acgattatgg
    73021 gattacttga tcctaataac acaaaaatta caggtgagat tttatataac gatctgaatt
    73081 taatcgacct gaacgaaacg ctctataata aaatccgcgg aaatgatatc ggaatgattt
    73141 tccaagatcc gttgtctgca ttaaatcctc tcatgagaat cgaagaccag atcaaagaag
    73201 gactttccta tcacacaaag atgaatgcag aacagcgtca agctcgtgca ctagaattgc
    73261 tagaacaagt agggattcct aatcctgcga gagttggacg ccaatatccc catgaactat
    73321 caggcggtat gagacaacgt gtcatcatcg caatcgcaat cgcctgcaaa cctccaatcg
    73381 tcattgcaga tgaaccgacg acagccctag atgtaaccat ccaagcacag attcttgatt
    73441 tactgaaaga ccttcaggaa gaaacaaaaa cagggatcat cttgatcact catgacttag
    73501 gagtcgtagc agaaatggct gatcgagtgg cagtgatgta tggcggacag ttcgttgaag
    73561 tagcaggtgt aaaagaactg tttgatcatc ctaagcatcc ttatacacgc tctttactga
    73621 actctatacc acaagaagga aatcatgatg cagaactcca tgtgatcgaa ggtgtcgttc
    73681 cttctctgaa aaacatgcct cgtaaaggtt gtcggtttgc accacgtatt ccatggatac
    73741 cagcaagcga tcatgaagaa gagcctatcc ttcatgaagt cgcaccgaac cacttggtac
    73801 gttgctcctg ctataagcat ttccacttta gagacgaaaa aggagaggtg tagatgacag
    73861 aattaatcac aatcaaagac ctgaaagttc attaccctat tcgcagtgga ttcttcaatc
    73921 gagtaacgga tcatgtatat gctgtagatg gtgtggattt tattatcgaa aaaggaaaga
    73981 catatggttt agtgggagag tctggctctg gaaaatctac tacgggaaaa gccgttgtgg
    74041 gattagaaaa ggtaacagcc ggacaaatca tgtatgaagg aaaagatgta acgaagcgaa
    74101 gcaaccgcaa aaaaatgggt tataacaagg atgtgcagat gatcttccaa gattcaatgt
    74161 ccagtttgaa tcctaaaaag cgagtgttgg atatcattgc tgaacccatc cgaaattttg
    74221 aacggttaag cgatcaagaa gaaaagaaaa aggtaaaagg actgctagat atcgttggga
    74281 tgccggaaga tgcgctatat aaatatcctc atgaattttc aggcggacaa cgtcaacgtc
    74341 taggagtagc ccgtgctgtt gctaccaatc caaaactgat cgtagccgat gaacctgtat
    74401 ctgctctgga tctatctgtt caagcgcaag tattgaattt catgaaacga atacagcaag
    74461 aatacggcct cagctattta ttcatttcac atgatttagg tgtagtaaaa cacatgtgcg
    74521 acaatatcgc aattatgtac aaaggtcgat ttgtagaaat cggtacaaga gaagacattt
    74581 ataatgaccc gcgacatatc tatacgaaac gtctgctttc agctattccg caaatcgatg
    74641 tagaaaatag ggaaagccac aaagaaaatc gacgaagagt agaacaagag tatatccaaa
    74701 accaaaaaga atactatgat gcgactggtc gagtctacga tttgcgtacg atcacaacta
    74761 cacacaaagt ggcgttgaaa gatggaggtg caagctaatg tggaaaacga ttctgcgacg
    74821 tgttttattg atgatcccgc aagttattat tttaagtgtt ctgatcttct tattagccca
    74881 agcgatgccg ggggatccat ttaccggttt gatcaatcca aatcaggatc cggcagtgat
    74941 cgaacagatg cgacaagcag ctggcttgaa tgacccatgg tatgtccagt acttccgttg
    75001 gatcggaaat gctttgcaag gcgattttgg tcaaagtttc ttatacaaac gctctgttgc
    75061 tgacttgatc ggcgaacgga tcatcaacac tttatatcta tcgatcttga cagttgtcct
    75121 tacttatttg attgctgtgc ctctggggat gcttgctggc cggtatcaaa attcaatctt
    75181 ggataagatt gtcgtaatct acaacttctt tagttttgct gttcctttat ttatcttcgg
    75241 cttgatcatg ctatttgttt ttggttatcg tttaggctgg ttcccaacaa gtggatcaca
    75301 aacactaggt ttgcaaggtg gatttatcac tcaatggata gaccgtttga aatatattct
    75361 gttaccatca attacccaag catttttggc gactgccgtc acaatccaat atctgcgaag
    75421 tgaagtaatc gattcgaaat cgctcgattt tgtcagaaca gcccgttcca aaggggtacc
    75481 gacgaataaa gtattcagtc gacatatttt ccgaaatgca gcgttgccga tggcttctca
    75541 aatggggtat gaaatcactt cgttgattgc tggttctgta gttatcgaaa agatttttgg
    75601 ttatccggga gtcggaaaac tatttattga ttccatcggc caacgggact ataccgtgat
    75661 cacatcctta gtattgattt taggaatcgc gacgctagtg gggacattac tttcagatat
    75721 catcatgagt atcgttgacc cgcgtattcg gattcaataa aaccaatcag aaaggagaat
    75781 ggatcgatga gtgaaaaaaa caatacagca gttcaagaaa gtattcctcc tatggggata
    75841 cgaatgattg ctcgagaatt taaaaaagat aaaattgcta ttttttcatt aggtttgcta
    75901 gtggttttat tattagtgat ctttatcggt gcgatgctga ccgatcaaga caaagtgatg
    75961 tatgttagta tcttcgacaa atacgctgca ccaggaacag tttcgacaca aggacaaaag
    76021 ttcattctgg gagcagatga aggcggacgt gatgtattag gacaattgat cataggtgct
    76081 agaaactctg ttacgatcgg atttgcgatc acgatcctta cttcgatcat cggggttgga
    76141 ttagggatca tctctggcta ctacggaggg atcattgaca acatcttgat gcggatcgtt
    76201 gattttatca tgattctacc gatcatgctg atcattatcg tcttcgtatc gattatttcc
    76261 agatacaatg tctggtcctt tatattcatc atgagtgcat tttattgggt agctaaagcc
    76321 cgattattcc gaagcaagac attatctgaa gcaagaagag attatgtcag tgcctcaaaa
    76381 acaatgggaa ccaatgattt taaaatcatg ttccgcgaaa tcatgccgaa tctaagttca
    76441 ttaatcatta ctaatttgac gatgaacttt gcggcaaaca tcggtatcga gacaactttg
    76501 actttcttag gtttcggctt gccggcaaat gtacctagtt taggtacatt gatcggttat
    76561 gcaagtaacg gagaagtctt agtgaatcgg caatggatct ggttacccgc atcaatcctt
    76621 attttagttt tgatgttgag tatcaattat gttggacaag cattcaagcg ttctgcagat
    76681 gcgcgccaac ggttaggcta gtatagaagc gaagggggaa ataggaatga agaaaacgat
    76741 ttttggattt gcagcg
//
LOCUS       DAFELK010000007        66154 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFELK010000007
VERSION     DAFELK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.007"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(165..464)
                     /locus_tag="LP433_000638"
     CDS             complement(165..464)
                     /locus_tag="LP433_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2004829.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            815..1447
                     /locus_tag="LP433_000639"
     CDS             815..1447
                     /locus_tag="LP433_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL2004830.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            1570..2208
                     /locus_tag="LP433_000640"
     CDS             1570..2208
                     /locus_tag="LP433_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL2004831.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(2327..2399)
                     /locus_tag="LP433_000641"
     tRNA            complement(2327..2399)
                     /locus_tag="LP433_000641"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2364..2366),aa:Thr,seq:cgt)
     gene            2520..2762
                     /locus_tag="LP433_000642"
     CDS             2520..2762
                     /locus_tag="LP433_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004832.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            complement(2901..3530)
                     /gene="upp"
                     /locus_tag="LP433_000643"
     CDS             complement(2901..3530)
                     /gene="upp"
                     /locus_tag="LP433_000643"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBL2004833.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(3664..4611)
                     /locus_tag="LP433_000644"
     CDS             complement(3664..4611)
                     /locus_tag="LP433_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2004834.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            complement(4764..6008)
                     /locus_tag="LP433_000645"
     CDS             complement(4764..6008)
                     /locus_tag="LP433_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBL2004835.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            complement(6183..7208)
                     /locus_tag="LP433_000646"
     CDS             complement(6183..7208)
                     /locus_tag="LP433_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBL2004836.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            complement(7230..7409)
                     /locus_tag="LP433_000647"
     CDS             complement(7230..7409)
                     /locus_tag="LP433_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004837.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            complement(7402..8241)
                     /gene="prmC"
                     /locus_tag="LP433_000648"
     CDS             complement(7402..8241)
                     /gene="prmC"
                     /locus_tag="LP433_000648"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBL2004838.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            complement(8234..9307)
                     /gene="prfA"
                     /locus_tag="LP433_000649"
     CDS             complement(8234..9307)
                     /gene="prfA"
                     /locus_tag="LP433_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBL2004839.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            complement(9310..9894)
                     /locus_tag="LP433_000650"
     CDS             complement(9310..9894)
                     /locus_tag="LP433_000650"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBL2004840.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            complement(10000..10469)
                     /locus_tag="LP433_000651"
                     /pseudo
     CDS             complement(10000..10469)
                     /locus_tag="LP433_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            10575..11177
                     /locus_tag="LP433_000652"
     CDS             10575..11177
                     /locus_tag="LP433_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2004841.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            complement(11281..11850)
                     /gene="lepB"
                     /locus_tag="LP433_000653"
     CDS             complement(11281..11850)
                     /gene="lepB"
                     /locus_tag="LP433_000653"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL2004842.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(12080..12847)
                     /locus_tag="LP433_000654"
     CDS             complement(12080..12847)
                     /locus_tag="LP433_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004843.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            complement(12844..13323)
                     /locus_tag="LP433_000655"
     CDS             complement(12844..13323)
                     /locus_tag="LP433_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBL2004844.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            complement(13448..14185)
                     /locus_tag="LP433_000656"
     CDS             complement(13448..14185)
                     /locus_tag="LP433_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBL2004845.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            14346..15746
                     /locus_tag="LP433_000657"
     CDS             14346..15746
                     /locus_tag="LP433_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBL2004846.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            15969..17321
                     /locus_tag="LP433_000658"
     CDS             15969..17321
                     /locus_tag="LP433_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBL2004847.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            17314..18012
                     /locus_tag="LP433_000659"
     CDS             17314..18012
                     /locus_tag="LP433_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBL2004848.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(18074..19225)
                     /locus_tag="LP433_000660"
     CDS             complement(18074..19225)
                     /locus_tag="LP433_000660"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBL2004849.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19238..19675)
                     /locus_tag="LP433_000661"
     CDS             complement(19238..19675)
                     /locus_tag="LP433_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2004850.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(19690..21456)
                     /locus_tag="LP433_000662"
     CDS             complement(19690..21456)
                     /locus_tag="LP433_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBL2004851.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            21720..22397
                     /locus_tag="LP433_000663"
     CDS             21720..22397
                     /locus_tag="LP433_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004852.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            22400..23527
                     /locus_tag="LP433_000664"
     CDS             22400..23527
                     /locus_tag="LP433_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004853.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(23727..24167)
                     /locus_tag="LP433_000665"
     CDS             complement(23727..24167)
                     /locus_tag="LP433_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2004854.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(24178..26211)
                     /locus_tag="LP433_000666"
     CDS             complement(24178..26211)
                     /locus_tag="LP433_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2004855.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(26213..27916)
                     /locus_tag="LP433_000667"
     CDS             complement(26213..27916)
                     /locus_tag="LP433_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2004856.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(28010..28960)
                     /gene="manA"
                     /locus_tag="LP433_000668"
     CDS             complement(28010..28960)
                     /gene="manA"
                     /locus_tag="LP433_000668"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBL2004857.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            complement(28999..30024)
                     /locus_tag="LP433_000669"
     CDS             complement(28999..30024)
                     /locus_tag="LP433_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL2004858.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(30233..31102)
                     /locus_tag="LP433_000670"
     CDS             complement(30233..31102)
                     /locus_tag="LP433_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBL2004859.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(31806..33698)
                     /locus_tag="LP433_000671"
     CDS             complement(31806..33698)
                     /locus_tag="LP433_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004860.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(33695..35422)
                     /locus_tag="LP433_000672"
     CDS             complement(33695..35422)
                     /locus_tag="LP433_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004861.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(35438..36088)
                     /locus_tag="LP433_000673"
     CDS             complement(35438..36088)
                     /locus_tag="LP433_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL2004862.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            36292..36588
                     /locus_tag="LP433_000674"
     CDS             36292..36588
                     /locus_tag="LP433_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL2004863.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            36780..37400
                     /locus_tag="LP433_000675"
     CDS             36780..37400
                     /locus_tag="LP433_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBL2004864.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(37492..38658)
                     /locus_tag="LP433_000676"
     CDS             complement(37492..38658)
                     /locus_tag="LP433_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2004865.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(38670..39023)
                     /locus_tag="LP433_000677"
     CDS             complement(38670..39023)
                     /locus_tag="LP433_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL2004866.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            39151..40173
                     /locus_tag="LP433_000678"
     CDS             39151..40173
                     /locus_tag="LP433_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBL2004867.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            40192..40353
                     /locus_tag="LP433_000679"
     CDS             40192..40353
                     /locus_tag="LP433_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004868.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(40612..41046)
                     /locus_tag="LP433_000680"
     CDS             complement(40612..41046)
                     /locus_tag="LP433_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004869.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(41156..43015)
                     /locus_tag="LP433_000681"
     CDS             complement(41156..43015)
                     /locus_tag="LP433_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2004870.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(43133..44293)
                     /locus_tag="LP433_000682"
     CDS             complement(43133..44293)
                     /locus_tag="LP433_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBL2004871.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(44600..46024)
                     /gene="araA"
                     /locus_tag="LP433_000683"
     CDS             complement(44600..46024)
                     /gene="araA"
                     /locus_tag="LP433_000683"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBL2004872.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(46040..46738)
                     /locus_tag="LP433_000684"
     CDS             complement(46040..46738)
                     /locus_tag="LP433_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL2004873.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(46695..48356)
                     /locus_tag="LP433_000685"
     CDS             complement(46695..48356)
                     /locus_tag="LP433_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBL2004874.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            48574..49974
                     /locus_tag="LP433_000686"
     CDS             48574..49974
                     /locus_tag="LP433_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBL2004875.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(50226..51305)
                     /locus_tag="LP433_000687"
     CDS             complement(50226..51305)
                     /locus_tag="LP433_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2004876.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(51391..52350)
                     /locus_tag="LP433_000688"
     CDS             complement(51391..52350)
                     /locus_tag="LP433_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL2004877.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(52362..53873)
                     /locus_tag="LP433_000689"
     CDS             complement(52362..53873)
                     /locus_tag="LP433_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL2004878.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(53895..54458)
                     /locus_tag="LP433_000690"
     CDS             complement(53895..54458)
                     /locus_tag="LP433_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL2004879.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(54464..55327)
                     /locus_tag="LP433_000691"
     CDS             complement(54464..55327)
                     /locus_tag="LP433_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2004880.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(55341..56237)
                     /locus_tag="LP433_000692"
     CDS             complement(55341..56237)
                     /locus_tag="LP433_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2004881.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(56412..57701)
                     /locus_tag="LP433_000693"
     CDS             complement(56412..57701)
                     /locus_tag="LP433_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2004882.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(57673..59190)
                     /locus_tag="LP433_000694"
     CDS             complement(57673..59190)
                     /locus_tag="LP433_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL2004883.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            59388..60278
                     /locus_tag="LP433_000695"
     CDS             59388..60278
                     /locus_tag="LP433_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBL2004884.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(60351..61175)
                     /gene="nadE"
                     /locus_tag="LP433_000696"
     CDS             complement(60351..61175)
                     /gene="nadE"
                     /locus_tag="LP433_000696"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBL2004885.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(61187..62659)
                     /locus_tag="LP433_000697"
     CDS             complement(61187..62659)
                     /locus_tag="LP433_000697"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBL2004886.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(63296..63658)
                     /locus_tag="LP433_000698"
     CDS             complement(63296..63658)
                     /locus_tag="LP433_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL2004887.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            63881..64633
                     /locus_tag="LP433_000699"
     CDS             63881..64633
                     /locus_tag="LP433_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2004888.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(64773..65696)
                     /locus_tag="LP433_000700"
     CDS             complement(64773..65696)
                     /locus_tag="LP433_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2004889.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(65711..65983)
                     /locus_tag="LP433_000701"
     CDS             complement(65711..65983)
                     /locus_tag="LP433_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004890.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        19149 a        13543 c        11483 g        21979 t
ORIGIN      
        1 atactagctg tttttgtgtt aattaaagga taaaatacaa tataaagaaa catctgtttc
       61 tttatttaga ataaaaaaat acagactctg ttcaaataaa tgaacctagc ctgcattatg
      121 agattgacta tactttttaa ttcattgaga tgaataactc gtttttataa atgcccaaaa
      181 gtaatcggtg ccgaagccat tcctcgacct aattcttttt caaattttcc tattgttgat
      241 atctccatat aaaacggtga tactggttta gacaattctc ccctgattgc taacggacgt
      301 aaactacgtt ccaaattatt tatgacttta ggataatact gacctttttc taagcctgtc
      361 tttgcgtcta tcaaaagtat acgttccttt tctttgatct ctggatttaa aacgagatca
      421 tataatttta gtaccatgtt ttctatttct tcacttttag acatcacgat ttcctcccaa
      481 aaatatattt cttcccacta cattctataa acaaagtata cgctacatct agattttttt
      541 aaatcattac tggattgtta aaacctttca atacactgtt atggcaacga tttttatttt
      601 aaaaacattc taaattaaat cagtaaaaat ttttattcta agatttttat tagaattacg
      661 cctaatttgt gtctctcagg gcaattctaa gaacgtttca agagatagcg acactatcgt
      721 tatcgaaaaa ggcgaaaacc tatctcattt tctgctaatg taagttggtt tagcttttgt
      781 taatatgact ttatgaaaat ggaggtaatt aaatatgatt tttcctaaag ttaatgaagc
      841 aagcttgaat aaaggatcct tttttcatat ctatgaaaac gaagattttg aactgtataa
      901 tatcctttca caaaaagagg tcatcgaaaa ccaaataatc tgccatccaa ttatttacaa
      961 atctattttc aagtatgcat tttttgcttc caatgatttt caaagaatgg agattaccga
     1021 ctgtatattc gaaaactgtg atttttcagg ctgtatattg acaaaaagca tgttgcatcg
     1081 cgtgaaattt gtcaattgta aattaacagg tactaaattg atggaaagtt atattgggaa
     1141 cacgttattc gagaattgta aaatggacta tgtaaattta tctggttcaa acataaaaga
     1201 aagtaccttt gagcactctg tcttatcaag cgcagatttt gtagactgtt ccctcactaa
     1261 aataatgttt tctactaatg atttagaaaa tgctagcttt tttgatactg atttaaaaaa
     1321 tatcgattta agtagcaact cctttgaaat gattgaagta cgctcggaac atctaaaaaa
     1381 ttgtacgctt aatcagttgc aagcacttgg ttttgctaga aaatttttac aaataaaagt
     1441 agtataatca aaatgaatat ataagataaa tttttagcaa tacaaatatc cataaaaaaa
     1501 cattgcctat tttaactctt catgtatact gactctatct tcaaaaactg aatagtagga
     1561 gttattatca tgaataacat tttaggaaaa aaaatagaac ttaaaaaagg gatattgggc
     1621 actattgtcg ttgtactcgg tttgttaggg ttgctatttg cgccatccat tattagcatt
     1681 ttttctttaa ctatcactgg atttatagca tttacacttg tttttggtaa aaaagatacg
     1741 aaaaaaatgt tctcgaaacc tgtcgctcct gtcaaaaata tagccaaata tttttttatc
     1801 aatgtagtaa tcagtgccgc agtctcggta tttttgcaac aaattttgaa atggggttta
     1861 acaggcaatc caataaatga ggctttcagc ccgttattat ttattatttt gcctatcatg
     1921 atacttggag aagaattgtt ctcagtgtat tttctcgcta ttttttctag taagttcagc
     1981 attcctgtcg ctagtttctt gtcagcaatc atctttggat ttatccatta cagtacttat
     2041 gataatggaa atattttaca cactgtagca cacatccttt tgatacaagg ggtggcaaga
     2101 ttgttattca accaagctgc cattaaaagc aactcgatca ttacaagttg ggcagttcat
     2161 gtgatatttg atttcacagc tatattgcta gtcgttttat tctcctaaat ttttatagaa
     2221 ataatacatg ctctattgct aagaaagcat actttatttc ctttaaacaa aaagacagat
     2281 gtatcaatgg attaaaaatc cttgatatat ctgtcttctc ttttaatgcc agctataggg
     2341 atcgaaccta cgacctacgc gttacgagtg cgttgctcta ccaactgagc taagctggcc
     2401 ttatccaaaa gaaattatat actctatttg gctgattgta aagagtccga tggaaaatta
     2461 gtttaatttc atgatatttt tcataaaacg tggtataatt gatgtgaaag gcaggtttta
     2521 tgaaaatggc aacttttgga aaatttgata caactatcgt accatcggaa attggtgaaa
     2581 aattcaagat caatactcac gtaatgttca caattcacgg caagtcgcaa actggaacga
     2641 tttcaaagca attgaaaaat tccgctgttg ttgagattga tgaaactgca gaaaatgcga
     2701 acttgatgac gcaaagtaag ggtgtagtaa tcgttaacta caaagaacta aaaaagattt
     2761 gaatttgacc atctctgcat ttttgggatg gtttttttat atgcaaacga aagctgtgaa
     2821 aaagctgttc tgcatcaaac gttaaaaatg accaaaaaag gatgtgacaa aagttgtgtc
     2881 acaccctttt tcgtatttac ttattttgta ccaaacaaac ggtcacccgc atcccctagt
     2941 ccaggaacga tataaccatg ttcattcaat ttttcatcta gagaagctgt atagatgtca
     3001 atatcaggat gcgcttcttg caaagctttt actccctcag gtgctgctac caaacaaaca
     3061 aatttaatgt tcgacgcgcc acgttctttc aatgcatcga ttgccatgat tgctgatccg
     3121 cctgttgcca acattggatc tactacaaac aactgacgtg catcaatgtc ttctggaagt
     3181 ttgacgaaat attcatgtgg ttccaatgtt tcttcatctc gataaagacc gatatgtccc
     3241 actttagcag ctggaatcaa ttccaagata ccgtcaacca ttccaatacc tgcgcgcaag
     3301 attggaataa tcgctacttt tttaccagac aacgtttttt gtgttgtttc agtgatcggt
     3361 gtttcgatca cgatgtcttc caatggcata tcccgtgata cttcatatgc catcaacata
     3421 gcgatttcat cgactacttc acgaaaaacc tttgttccgc agtttttgtc ccgaataata
     3481 gttagtttgt gttgaatcaa tggatgatcg atcacttgaa atttgcccat tttttaagct
     3541 ctcctttgtt ctgtcgtttc tttttaattg taaaacaaaa tcaagtgatt gactagtcaa
     3601 actcgccatt tttcctaaga aaatccgttt ttgaaaagaa gttttcctgc ggacaagcaa
     3661 agcttattct tttttcttga tccaagaagt agataatgcc attgctgcac gcgttgcctt
     3721 tgtctgatcc atagcattta ccatgacaaa atcatggatg attccttgga agcgtacttg
     3781 tgtaacagga acccctgcat cacgaagttt gcgcgcataa gcctcacctt catctcttaa
     3841 tacatccgct tctcccgtta aaatcattgc tgaaggaaga tcatttagtt catttatatt
     3901 tgctctcaaa ggcgaagctg tgatttcagc acgctcttct tcattcgtcg tatattggtc
     3961 ccaaaaccac atcattcctt ctcttgtcaa aaaatagttt tctccgaatt catgatagga
     4021 atctgtatca aaatcagcgt ttgtgactgg ataatacagc aattgcttgg atattgggag
     4081 gccctttcgt tcttttgtta agatcgtcat gactgtagcc atgttaccac ctactgaatc
     4141 tcctgcaacg attagattct cgagatccag attttttgac ttggctaatt tattcagctg
     4201 ttgcaacaca gcataatttt gttcaattgc tgttggatat tttgcttctg gtgatcgact
     4261 atattctgga aagacaacga cggaattcgt acgaaccgca agttctctga tcaatttatc
     4321 atgggtttga gcactgccaa aaacccagcc tgctccatga atataaaaaa taactggtaa
     4381 tttatccata ttcccttctg gtcgtacgag acgaatattg agttttcccc attcgccagt
     4441 atccaccatc aagtcttcaa tatcgacgga atatttgttc acaggtgatt cttgtacttc
     4501 ttctagtaaa actcttcctt cttccggtgc tagttcatag atacgcggat gaggcgcatt
     4561 tgcatcactg aatgctactg cttccttttc taacgagata cgatcagtca tgacttttcc
     4621 tccctgagat ttagtgtgaa gactaaaatt acacctcata tactagagag catcaccgat
     4681 attgtcaaag aatccgtttt cccaaaaaat aaacagaaaa gcccaacatt gaacttttct
     4741 gtttactaat ggaatttaaa tttttatttt ttatgcaacg gaaatttttc agttaattcg
     4801 cgtacacctg ttttgacttc gtctagttga gcgttatcat cttttgcttg taatgctttg
     4861 acaactagtt cagccacttt tacagcatct tcttctttga acccgcgagt agtgattgct
     4921 ggcgtgccga ttcgaatacc gcttgttttg aatggactta gtgtttcaaa aggaatcgag
     4981 tttttattta cagtgatatt cacactgtcc aaaatgctct ctgcttcttt tccatttata
     5041 cctaactcgc gaacatcgat caacatcaga tgattatctg tcgcccctga aatgactctg
     5101 gttccaattg cttgattgaa aactttgacc attgcttttg cattggcgat gatttgttca
     5161 ctatattctt taaatgcagg atctaatgct tctttgaatg ctactgcttt acccgcaatc
     5221 acatgctcta gagggccgcc ttgaatacca ggaaataccg cactatttat tttttttgct
     5281 aatgcttcat cgtttgtcaa aatcatgccg cctcgagggc cacgcaatgt tttatgagtg
     5341 gtagtcgttg tgatatctgc ataaggaact ggattaggat gaagtcctgc tgctactaat
     5401 cctgcgatat gtgccatatc taccatcagt tttgcgccta cttcatctgc gatttctctg
     5461 aatttcgcaa agtcgatcgt tcgtccgtaa gcactggcac ctgctacgat caattttggt
     5521 tgatgttttc tagctaaaat acgtaccaca ttataatcaa taacttctgt tgtcggatca
     5581 acaccgtaag caacaaagtg ataggttttg ccactgaagt tgactggtga tccatgtgtt
     5641 agatgtccgc ctgcggaaag atccattcct aagatcgtgt cccctggttc taccaaagcg
     5701 agataagcag ccgtgttggc ttgagagccg gagtgaggct ggacgttcgc aaatttcgct
     5761 ccgaataatt cttttgcacg gtcaatcgct aaattttcaa cgatatcgac aaattcacac
     5821 ccaccataat agcgatgccc tggataacct tctgcgtatt tatttgtcaa gatacttcct
     5881 tgtgcagcca tcactgcttc ggagacaaag ttttcagagg caatcagctc caaattatgt
     5941 tcttgtcttt cttcttcttt ggcgatcgca gcccaaagat cagggtcaaa cgttttgtaa
     6001 tctaccacaa acaacagctc ctttttattt tcctacaatt ttatttttcc catcaaaaac
     6061 aaattgccaa atattcgtat ctcttctatt acgattagtt acgcttagtt tttcgttcac
     6121 tgatagaaga tttacttgat agcattgtat catactaaaa gaatgcgaca ataaccaatt
     6181 gatcattttt caaaataatt ttgtcctgct gcttttttca agcgattcat gtaagcattc
     6241 cccaatccag tttctggata cacttgtaca aaaatcaaat ctaatccaag tgttggttca
     6301 tctaatcctc ttagacctgc aaacaatcct ttagccgccg cttctactga gttgtcgtta
     6361 tacatataaa cagctgcagt atctgtccgc acttgatccg caatttcggg gcttgctatg
     6421 acacctgcac ggatcttctt attttttgcc cattgaactg cagttgacca atcgccatct
     6481 ctgaccatca gaacacgtgt atcgggtgag tagtgtttgt atttcatccc aggggctttt
     6541 ggtgtttcat tttcttttac aagatgctga tcaatagcaa caggagattc gatgactgct
     6601 tcgatttgtt ctttcgttac tgcacctggt cgtaaaatca taggcatggc tgttggatca
     6661 cttaaatcaa gaacagtgga ttctacacca attcgcgtag ctccatcatc aataatcccg
     6721 gtaatttttc cttgtagatc atgatataca tgatctgcag tcgttggact tggttttccc
     6781 gacgtatttg cacttggacc gacaagcgga acaccggaaa gttcgattac ttctagtgtt
     6841 tttttgttat ccggtatacg aaatgcagct gtggataatc ctcccgtcac aactgagggc
     6901 aaagtgtctt ttttgatctt aaatatcaaa gttaatggtc caggccagaa gttcttcaca
     6961 atcttctctg ctgccggatg aaagttgtcc acatactctt ttacttgttc aaaagaggcg
     7021 acatggacga ttaatggatt atcttgcggt ctccctttta cagaaaacac tttcttgaca
     7081 gcgtttggta aaagagcgtt ggcgcccaat ccgtatactg tttcggtagg aaaagcaaca
     7141 agttctcctt ctttcagtgc ttcggctgcc tcttgcaatt ctgtttcatc atatcgtttc
     7201 gtttccacag tttatccaca accccttttt catacattct tattttgtct gagtttatcc
     7261 tcaagttttc cactgtttgt ggataatcta tttgtcaata gtggataaac ttgttgataa
     7321 accaaaaagt cgtttacatc cttgtcaaat aagtgttttt ttataataaa aaaacaaata
     7381 aaaaattttt catccacaac ttcaaccata aacttggatc attcgttcat tgccaaaaag
     7441 atcctttttt atcgccactt ttttatctgg aaatgcttgc tgaaatattt tttttactgc
     7501 ttcaccttgg cgaaatccga tttctaaaaa aatctttcca tttgatttta gtacgcttgg
     7561 tgcttcaact gctatttttt cataaatagc taatccatcg ttctcagcaa aaagggccat
     7621 tttaggttcg aatgaccgga cactttcatc catcagttcc cattcattcc gactgatgta
     7681 cggcggatta gaaataatca catcaaattg ctgatccatt actggtccta atgtatctcc
     7741 atgataaaaa ctgattttcg ttccttcttt ctgagcattt tctttcgcta cttctaatgc
     7801 ttcttctgaa agatccacag cagatatatg ccaatttttt cttgctgctt tcaaactaat
     7861 agcaattgct ccagtccctg tcccaatatc tatcacttct aacggtacac caggcgtctc
     7921 gtctaaacac cattcgacta actcctctgt ttctggtcga gggatcagtg ttgcttcagt
     7981 tacctttaac cgatgatcat aaaaatctgc atatcctagc aaatactgag gtggatgatc
     8041 tgcaagcaga agtcgcagat cggtttcgat caaccgctgt tcttcttctg aaatctcttc
     8101 gttcatatga aggagccaat caagtttttt ccattgtttt cgttccaaaa ataaaaattg
     8161 gatactatat gcttctttcc catgatcctc taaaaaagaa gaagcccgtg acaggacttc
     8221 tcgataggtc attttaccca ttttgcatag cttccagttt tgatgtttga tcatacatga
     8281 tcaatgcatc aacgatctca tctaatttcc ctgctaaaat ctgatctaat ttttggatag
     8341 ttaatccgat acgatgatca gtcacacgat tttgcgggaa attatacgtc cggatccgtt
     8401 ctgaacgatc cccagttccg actgctgatt ttcgattggc atcatactcg ctttgtgctt
     8461 cttgctggat cttatcgtac acacgagcac gcaagatttt cattgctttt tcacggttct
     8521 tgatttgaga acgttcatct tgcatagcaa caacgatccc tgttggtaag tgagtcaaac
     8581 gtacagcaga tgctgtttta ttgacgtgct gtccgccagc acctgaagca tgatagatat
     8641 ctgtacggat atctttgtct tcaatatcga tctctacttc ttcagcttct ggcatcacga
     8701 caactgttgc ggtggaagta tggatacgcc cttgcgattc agttgaagga acacgctgga
     8761 cgcggtgcgc accactttca tattttaatt tcgaatatac gttgtctccg gtgatcatca
     8821 tgatcacttc tttatatcca ccgattccgg taacgttagc ttccatcact tctgttttcc
     8881 agccttgtgc ttcagcatac ttttggtaca tattgaaaag atcgccagcg aataatgctg
     8941 cttcgtctcc gcctgctgct ccacggattt ccatgatgat atttttatcg tcatttggat
     9001 cttttggtaa aagcaagatc ttgatttttt cttctaagac ttctttttct ttttttaatt
     9061 cagataattc ttcttttgct agttcagcca tttcatcatc cagtttttca ccaagcagtt
     9121 cttctgtatc ggtgattcct tgtactactt ctttataacg acgataaact tcgactgttt
     9181 cgcgcgtgtt tgcttcttct tttgaaagct gcataaaacg ctttgtatca gaaatcactt
     9241 ctgggtcact taaaagttct ccaagctctt cataacggtc ttcaattgct tgtaattgat
     9301 cgtacatgct tattctcctt ctgtaatcat tgatgggtga aagtaatgtt ttcgacaaac
     9361 ggggtaataa gcttcatttc cgccaatttg cacttgatcg ccttcataaa cagggtttcc
     9421 atcaatataa tgtaaattca tgattgcttt tttgtggcag aaccaacaga ttgttttcat
     9481 ttcttcgatt ttgtctgcat aaagcaataa atattttgat ccttcaaata actcgtttcg
     9541 aaaatcattt ttcaaaccaa atgccataac cggaatatcc aattcgtcca caattctcgt
     9601 aaaagcaatg acatgtttct tttttaagaa ttgcgcttca tcgatcagca cacaataggg
     9661 tttgctttcc attttctgaa ttacgtcaaa tacgtctgtt tcttcaaata tcggcatcgc
     9721 attacgtttc agtccgattc ggcttgaaac aacgcctaaa ccatctcttg tatcaatacc
     9781 gcttgtcatt aagacaactg gcttattttg ttcttcataa ttatgtgcga cttttaggat
     9841 ctcgatcgtc ttgccgctat tcattgcgcc atacttaaaa aatagttgtg ccatgctctt
     9901 tttcaccttc cagtttgttc ctatggtatt atacttgatt ttcagcattt tttacagtga
     9961 gaattttcat caagcacaga ttagtattaa atctattgct cacttttgtt ccaatttttt
    10021 gacaagaact aaacatgggt tccattcatc ccataaattt ggaaaaactt ccaaccttga
    10081 aaatcctaat gattcgtaga aacaaatagt ttgatcatat atagagtagt gcccctcgtc
    10141 tacagtcttc acttgcaaat atttgtaatg ttttgctgcg taaccttctg cttctttaaa
    10201 aagttttgtt cctaatcctt ggtgatgata gtcttttttt attcccatac aatagaatag
    10261 atttcggcag tatcttcact tgtctgtgaa agagtgataa agcctaaata ttcttctttt
    10321 cttttttcac accataaagg tagtttactt gattcctcga tatatttttc cgttgattca
    10381 ggaagcccaa accactcagg caagtctagt aatatttctc ggacacactt tcctttttcc
    10441 tctctatctt ttacaaacga tatcggcata ttctttctag attctccctt tttgaattga
    10501 gtatagcatg ctttctttct tttcacgtgc tataataagt taaaatttca aagttttacg
    10561 taaggagcta tttgatgaca aaaaatattt ttgattccat cgctaaccat tatgattccc
    10621 ctgaccgtca agcattagcc aagattattc gcgaagaact aactacttat ctaccgcgcg
    10681 acagccacca aaaagtcctg ctggattacg gaggcggaac tgggcttgtt agtttaccgc
    10741 ttgcggaaag attcaaagaa ctgatcattg ccgatgcttc agaaactatg ctgaaaatgg
    10801 cagaagaaaa gatccaagca gcagatctga aaaatgtccg aacgatccac gctgatgctt
    10861 ctgtcgaatt tcctgctgtc caagctaatc tcatccttct atcacttgta cttttacaca
    10921 ttcctgatac ggagaatatt cttacaaaac tttatgaaat tttagctcct ggcggtcaat
    10981 tgatcatcgt agactttgac aagaatgaac aaattagtca tccgaaagtc cataatggct
    11041 ttagccaaga agaattgaat aatcgattgg aaaaaacggg ctttgtctct gctactagtc
    11101 ataccttcca tcgtggggaa aagctattta tgaacaaaaa cgcttcgctt ttcttatcca
    11161 tcagccaaaa agcttaaaat gagattgcaa aaaaagtgag caactccaag aaataagaag
    11221 gaattttcgg aaaaagaagc tgtgacaaaa aacatgtcac agcttctttt tattttttca
    11281 tcacatgatt ttaatttctg aaagaggcca ataacggaaa acaacttttc cttggatcat
    11341 atctttgtcg actaacccaa acattcggct gtcttttgaa atcaagcggt tatcgcctag
    11401 aacaagatac tttccttttg gcacagtata ttcaaagtca ctcgtaaagg tggatgaact
    11461 ttctgcttgt gcttggaatc ctgagctata agcatattct ccttgtaact tatcttctga
    11521 aaattctttt ttgaactcat ccagataagg ttcatcatac tttttgccat taatggtcaa
    11581 ctggtcattt tccatcttga ctgtatctcc aggcataccg atgatccgtt taacaatcat
    11641 ccgttcttca tcccccggtt cctttgtagt aataatatcc attcgttcat agtttgagat
    11701 cttagatgaa atcaatcgtt gtccatcact taatgtaggg tccatcgaat gcccgtttac
    11761 agtaactggt gtaaacacgt acactctagc taataaaata gccgctaata caaggatcaa
    11821 aatcccccaa tttttcaaaa attctttcac agcttacctc ctacttgtat tttcctcgtt
    11881 atttattacg ttttttcaca atacttcgtt gtactttctt tattctacaa tgtttataaa
    11941 tgaaaggaaa gaataagtga tgtgttcgtc ttatctttct cgttatataa aaaaggaacg
    12001 tgacaaaaga cgtgtcacat cccccttatt ccgaataaac gtttttatcg caaccactga
    12061 tacacggcgt ttcatcacat tatgaatgtc ttcttctttg gctacgacta taaaccactg
    12121 gttcttcctg cgactgtgcc ttttttgcaa tcaatttcag acgataaggc tcatgatagc
    12181 gtaacccgtc tttgacaaaa tcaccgccga cgatgaacaa tccgacaggt tccaatgtgt
    12241 cttctgttga gtcaagtcga atggtcccta ctttttccat gtccgagtag cttcgtccaa
    12301 tatttagaac atactctttc tctcctgttt tcttgacata gtaataagga tacaatgtat
    12361 ttctatcgac cagaaatcca tccatgcgac cgagttcatt tgttttgatc tcaccatttc
    12421 caatcaaata ccgcatattc tcggctaatt tcaattgata atcttcgtca taagaaacca
    12481 tgacctcttg tgtattcact ttatcgatcg aatttccatt atctatcgat tcttctgtct
    12541 ggatgttgaa cgcttcatca ggtaaatact tcacaaaaag ctgagtgaca tcggctttcg
    12601 tgtttttatc taaaaagtaa taaaatacat ttaaaacagt aaaataaaca agcactagaa
    12661 atgcaagtcc atataagaaa aattgaagat agttttggtt ttgccaaagt ccataaacaa
    12721 ttctcaataa ataaagcgtg ggaatcacac ttaaaatcgt atatccacgg ttaagatatt
    12781 taggactgat gtctaaatag ccaaggaatt tatgcacccc gttgataagg tctagtaaaa
    12841 atgtcattga gaatcacctg cttgctggtt atacgtttgg gtatttcctg aatcttggtt
    12901 ttgctgtgct gtacgtgctg catcatcatt ttgcgtgtta tcatctacag tcgtactgct
    12961 tggtatcgtt tcggagctag cacttgtatc cggacttgta cttggattgg ttgaatccga
    13021 tggagtgcca tctggtaccg tattacttgt ttcgcttgag ctgtcagttg tatatgtctc
    13081 atcatacgac gaactagttg ttgtatcgtc ccatgtactt gtcgtagtgg tttcattcaa
    13141 actttccgtt gttgttggtt cagatgtcga gactgaagta gttggtgttg tttcttctac
    13201 agtactagaa cttgaacttg gtgcacggta gctggaacta ttcacaatac ctgtagtagt
    13261 cgcgacaatc gtcgagattg ttaatacagc gattggcttc aaaataggtg ctacttttcg
    13321 catcttatct cttccttcat tgaaatttat tcttgtttcc ttactttact acggacaaat
    13381 tatacagtct accttatttc taccataaat tctttatttt tttcttacgt ttttccgaaa
    13441 gatttcttta attttcctca aaaactacgg ttgatgtttt taagtaagct tttgcttccc
    13501 gattgatttc tttcagatcg catccttgct gcttggcagc gaacacgcaa ccacaataac
    13561 attggcgata aatatcatac tctttgcaca tttgcaaaga gcgttcatag cctttgtttt
    13621 tcttgaaatc acttggcaag tattgtgtcc cgtaaatctt ttggatatcc attccgatct
    13681 gattgatcaa agctgcattt ttctttggcg agatggtcag ggcacttcca aagtaatcgt
    13741 atcctagttc ttgcgctttt tgcgcaacaa gatctaatcg catattgaag catgcactgc
    13801 agcgagcacc accttctttt tcgttttcaa gatggtttgt taaaaccatt ttggtgaatt
    13861 catttggacg gtattcatca acgattagcg caacatgatg gtcagttttc tcattaaatt
    13921 ggtctacaaa tcgtttttgt tcatgtaatc ttcgcaaata ctcactttta ggatgaatat
    13981 tcgaatttga aaaaaataac gtgatctctg catattgaga catgaattcc aatgtgtgcg
    14041 tactgcaagg agcacagcat gtatgtatta atatcttagg ctttacttct tctttctccc
    14101 attgcatgat catttttttc agaactgtat cataatttat tttttgattt ttcatttttt
    14161 ctacgatttg ttgagcatta atcaatttgt tattcctcct ccttcttttt tctaggattt
    14221 tccttattat aagccatttc tattttaatc gaaagctgta ttgttatctg tttgataatt
    14281 tctttgagta ttcctaattc cccttgtata ctggtagaaa cgactattgt caggaggata
    14341 gtactgtgca tgttgattta ttctttcgaa ggctgcagcg gcgaggacag aagtttgctg
    14401 ccaatcattt ctcatcgatc caaatcatcg ttttttatta tatattgatg acggtcttat
    14461 cactcgttct attttatatg ccgatttttc gcgaaccaga tagccatgtt tcttttgtgg
    14521 acatgctgtt catggcaatc agtacagtga gtgtgactgg actatcgact tttgatatca
    14581 attctgtgtt caatgataac ggtattatac tgctggaaat attatttcaa gttggtggtt
    14641 tggggatcat gatgatttct actgcttttg tcattttttc taaacgacgg atcacactga
    14701 aacagcgaca gctgatcatg acggatatga atcaaccgcg tttgtctggt atcgtccgac
    14761 tgattcggat cacttttgct attttaatct ggtttcaatt actttttggg acattctttt
    14821 ctatttattt ttattacaga ggctattttg atcgttggcg tgatgccgtt ttttacggtt
    14881 tttatcaggc gatatcggct gtcacgaact ctgggtttga cgtcactggg gattccatca
    14941 agccctttgc acatgactat tttttcttga tcctgatcat gtttttgatt tttgtcggag
    15001 gaattggttt tcctgtattg atggagtgcc gggaatggct attatacaaa cgttccaatg
    15061 cgaagcttcc gtttcgtttt tccttgttta ccaaattagc tgtgttagct tttgttatct
    15121 tgtttgtttc gggaactgtc ttgatttatc tattggaaaa ggaccattta ttccaagatt
    15181 ccaatatgag tgtcaaatgg atcaattcga tgttttattc gattacgact cgtaatgctg
    15241 gtctgcagat tcacgatttg ggtgattttc aaatcacaac actgatcatt ttttctttac
    15301 tgatgtttat cggatgcagt cctagttctg taggcggcgg gattcgaaca actactgtag
    15361 caatcatcgg tttgtatcta tattccttcc tcaaaagtga agataacatc aatatttttg
    15421 gacggagaat cgatcaagat gatgtgcgaa aatcagtcgt tgtctttatg ctttctcttg
    15481 gtatgtgttt cttttgtatc gtttttttat ctgctacaga agaacaaacg ctgatctcga
    15541 tcatcatcga agtaacttct gcgtttggaa caactggttt atctttaggg attaccggag
    15601 acttgtctgt tgtgggcaaa atcacgattg ctacactgat gtttattggg cggatcggaa
    15661 tgctatatac attgatgtta ttcgtgccaa aagaaacacg agatctaggc tatgaatatc
    15721 caagcgagaa aattattatc ggttaaaatg ggaatatagg taagagggaa taataaaatc
    15781 acagcagctt gaaacaatca ttttgtttca agctgttttt ttgttaaatc atgcgatttt
    15841 gtccgatttc atgcactttc agccgtaacc ttttcttaag aataagaaaa gcaatttaac
    15901 ctttttttca acatatggta tgattagttg aatttattcg tcagcaaatc gtttttggag
    15961 gttacataat gggaatacgc agtcattttg cgattgcagt tggaaaaacg tcgcaatggg
    16021 cattaaaaac tttttttaaa ggcggatcaa gtttaccagg taaactagcg ctgaaagtcg
    16081 atccacatat actagatagt ttggcaaaag actaccaagt cgtcgttgtc accggaacaa
    16141 acggtaaaac attgactacc gctttaacag tcaatatttt gcgccagcaa ttcgatgaag
    16201 ttctaaccaa ccctactggt gcgaatatgg tacagggaat tgtatcgact ttcttgcagg
    16261 caaaaccaaa aaaaggacag aaaaagtttg ctgtcctaga aatagatgaa gcaagtttga
    16321 gcaaagtcac agaatatatg aaaccagaac tgttcttatt tacaaatatt ttccgtgatc
    16381 aaatggatcg gtatggagaa atctatacga cctataaaat gattgtagac ggtgccgcaa
    16441 agtcaccaaa tgcaacgatt atcagtaacg gtgattcacc aatcttcaat tctatcgaaa
    16501 cagtcaatcc tagaaaatat tatggctttg accatgaaga agatcgtgaa caaatggctc
    16561 attacaatac agacggtgtc ttatgtccaa attgtcatca catcttgcat tataaaatga
    16621 tcacttatgc aaacttaggg aaatattact gtccaaattg tgacttcaaa cgtcctgaat
    16681 tggattatcg attaactgat atggtacgga tggacaatgt gtcagcagat ttcgtgatcg
    16741 atggtcatga atacggaatc gaagttggcg gtatgtataa tgtctacaat gctttagcag
    16801 ctactgcagt ggcagagtac ttcaatgtcg atcctgataa aatcaaacaa ggtttaggat
    16861 atgacgagaa agtattcggc cgacaagaag tcatcaatat caatgggaaa aaatgtacat
    16921 tagtacttgt caaaaatcct gtaggtatca atcaagtaat cgatatgatt ggtctagctc
    16981 cttatccatt ttctttagtg gctttattaa atgccaatta cgcagacgga atcgatgtca
    17041 gctggatttg ggatggtaat tttgaaaact ttgccgatat ggatatccca gctgttattt
    17101 ctggaggaga ccgtcataca gatatgactt tacgtctaaa agttgccggg attccagaaa
    17161 ataaattgac agaaacaaaa gaattaccag aagtaatcga aaaaatcaaa gaattgccaa
    17221 ctgagcatgt ctatatttta gctacttaca ctgctgtatt gcagcttcgt aaagaactag
    17281 ctgctcaagg atttatcaaa ggaggaatga accgtggcta attatgaact caatatcgcc
    17341 cacctttatg gaaatttgat gaacacatat ggtgataacg gaaacctttt gatgttgaaa
    17401 tatatagcag aaaaaatggg ggtttcttgc catacggaga tcgttagtat acatgaacct
    17461 tttgatgctg ataaatatga cttggttttc tttggcggtg gtcaagactt tgagcaatta
    17521 atcatttcaa aagacatcca gaaaaagaaa gattctttga tcaactatat cgaaaatgat
    17581 ggcgtcatgt tagccatttg tggtggctac caattgctag gtcactacta catgggagct
    17641 aatggagaaa agatccaagg aatcagtgca ctggatcact acacgttaag tcaggaaaat
    17701 aaccggttta tcggtgatat cgttatccat aacgaagaat tcaatgaaac ttattatgga
    17761 tttgaaaacc acaatggtcg gactttctta ggtgaaggtg aacgaccttt ggggaaagtg
    17821 gtacaaggtc aaggaaataa tggtgaagac caatctgaag gtgtcattta ccgaaatgtc
    17881 ttcggttctt atttccatgg acctatcctt gcaagaaatg agaacctggc agctcgtttg
    17941 atccgcctag ctttagaaca acgttacggt aaagaattgg atctgcccta tcttgaagga
    18001 caaacagcct agttattcga aaaaggggaa tgtgacaaaa atttcgtcac attccccttt
    18061 ttcgtatcct attttaagcg acttgcttgg cataacggtt cacgttttgc ttgatattcc
    18121 cgattgtttt cggatcattg attcctgtga cttcttgaat caattgttcc aagttttcat
    18181 ggatcttcat ttcatgcaat tgacggcttt gttcatcttc aggatcatag taattaaaaa
    18241 taatccccat tgttgccgtc aaatgtgggc aagtcaagtt atgttcttgt agttctctca
    18301 ctggacgtgt aaatctttct tgataaccta acttacgtaa tggtgtccga gcgacacgtg
    18361 tgatcgcatc agagatattt ttgttttgga agcgatgaat gattttttca atatacgcat
    18421 gatgctgctc tgcatcaaac ccccatttgg caatcagcaa acttcctgtt tcctgcaaaa
    18481 ctgattttaa ttgtgccaca actaacgcat cttgcattgc ttcatcaatg gtctggtaac
    18541 ctaacaaggc acctgtataa gcgacagtcg catgaccagt attgacacta aatagtttgc
    18601 gttcgatata tggttctaga tcatctacat ataaaacccc ttttaattgg atttttttat
    18661 tttttctttg gctatcgtca atgacccatt ctttgaaagg ttccacttgg acgaataaag
    18721 gatcttcatg gtgttgtaat gggacgattc gatcgactgc tgcatttgga aagccgatat
    18781 atttgtcagt aaatgatgtt tccggaagat atttatacac ttctttttct agaaatgctg
    18841 aaccgccaat catattttca caggcaatga tatctaaaga tgttgtgctt ccttcctttt
    18901 ctctttcttg gatacctttt gcaatcaact cagcaataaa aggtaagata ttcgggccaa
    18961 tggcggtagt aactaaatct gcttcagcga tttcttggat tactttttct ggatttgttt
    19021 gattgttgat tcctttgaca ttttttacag tgattttttc ttttgattca tctgctaatt
    19081 cgatttcgta ttcttttctt tcatttaaag catcaatgat cgtgtgattc acatctacga
    19141 aagtaatctc aaatccatta gctgccaaaa cctctccaat aaatcctcga ccgatatttc
    19201 ctgcaccaaa atgtactgct ctcatttttc tctctcctta agcaattgct agattttccg
    19261 ttacttcttc tttgctgagc gcgtctgcta gctggacaac attgtccata tcactgcaat
    19321 aaagtgcgat ttgctgtaca agttgcaaat gctcatctcc gactcctgca ataccgaaca
    19381 aaacagtcgc aatcttttct tcttcttcgg taccaaaatc tacaccatct ggtacttgaa
    19441 cgacacagat gccggatttt ttcacatatt tttttgcttc atctgttcca tgaggaatcg
    19501 cgataaaatt ccccatataa acagataaca ttttgtctct atctaccatg gcatcgatat
    19561 attcctcatc aacgcaccct gcttctacaa gcatctgacc gcaatagcgg atcgcttctt
    19621 ctttggtttt aaaagatcga ttgagctcga tcatgtcgaa tggcaaactt tgcatgctgt
    19681 tttcctccct taagctgtct gtttcaaata ttgtgcaatc gattcgtatt tttgcggatt
    19741 gaccatgctg ttgactgata aatgaatgga ttgaggtgca gccatctgta ctttttccgc
    19801 taaactttct ttggctacga tcagtgaatc aggttcatct tttaaatctt ggatattgac
    19861 ttttcttaac gggatagtta aatggttctt gtctaatata tctttgagca cggtcatccc
    19921 cattgttgct gatccggaac gatcatcgtg gacaagtaga atctctttga tttgtttgat
    19981 gtttgctgaa agaaactctt ctgctggctc attctcaatt tcagaaactg atgttttctg
    20041 cttgctgctt aattcttgaa tgatttcatc atatcgaggt gaattcaaaa agttttctac
    20101 tgagacaaaa cgcgcgctcg gtgctttttg ttttgctctt tcttgtagtt cgacctgagt
    20161 aacgatcaat gtattcgagt catctgtcag ttggctgatt gcttgattgg tcaccgtttg
    20221 aggcaagtct gcttcctgta ctttttttct caagatcgaa gcgcccatcg cacttgatcc
    20281 cattcctgca tcacaagcaa aaatgatttt ttgtacgcca gagaatgtag ctccttgagg
    20341 aataccttgg gcacctttgg aagcttgctt agctgccttt gtctcttgaa cagatttttc
    20401 gaagtcttca tttgtatctt tcgcatccgc tttcaaaatt actgcagaaa taccaaacga
    20461 aacagctgcg gcaacaatca cgcccaaaat aacaggaagg taagaattga acggtgtcat
    20521 cgctagaatc gcaatgatcg accctggaga agctggcgct cttagtccag catccatcaa
    20581 ttggaaaatg aaacttcctg acattcctcc gcctataact gataagaata ataacggttt
    20641 catcataacg taaggaaaat agatttcatg gatcccgcct aaaaagtgaa tgatcatggc
    20701 tcctggtgct gaagattttg ctgctccttt gccaaacaaa gtaaaagcaa gtaatacgcc
    20761 aagtcctgga ccaggatttg cttcaagcaa gaatagaata gattttccag cctctgctac
    20821 ttgttcagtt cccaatggtg tcaaaatccc atgattgatt gcattattca aaaataagat
    20881 ttttgctggt tcaataaaaa tacttgtcaa tggaatcaaa tgggcagata aaatgatctc
    20941 tacacctttt gccattgctt gagtcaatgc atcgacaact ggaccaatcg cagaaaaacc
    21001 taataacgct aatccaaaac cgataagacc tgctgaaaaa ttattgacta gcatttcaaa
    21061 accggatttg atccgttttt ggaatagctg atcaaatttc ttgatggcat atccaccaag
    21121 aggtcccatg atcatcgcgc ctagcatcat tggaatatct gttccgacaa tcacacccat
    21181 cgttgcaatt gccccaacaa ctgatccgcg gtcaccagca attacttttc cgccagtata
    21241 accgatcaat aaaggaatca gataagttag cattgggctt accatggtag cgaaagcctc
    21301 atttggtaaa taaccatctg ggataaatag agccgttaat acaccccagg caatcagtgc
    21361 tccaatattt ggcatgacca tgcttgataa agtactgcct aatttttgta ccctcgcttt
    21421 tagcgaaatg ttgtttttgg gaatcgtccg ttccattttg tctctccctc tctccttttg
    21481 atactctaat tgtatccgct tactaaaaag agaaatagtc gtactttggc acgaaacttt
    21541 gtgccaaagg tttgagtatg tcaacaaaat aaaaagattt cggtatcaga aaacttcaat
    21601 tttaaataaa actgttattt taattttttt ataatatgca aacaataact tttgttagca
    21661 tttaatttag atgttttcca ttctattatg ttattaaatt ttatattgga ggcctatcta
    21721 tgacattact gatcaaaaac atgaacatga aacgtggtaa aaaacgtgtg attcgacaat
    21781 tgaatctttt agtagaatca ggagaagtag ctgctttgat tgccccgaac ggatttggca
    21841 aaacaacttt gctgaatggc attgcccaac tgctgccaac aacttatgat caattgtccc
    21901 ttcacaacat ctctcctact gcttatacag attatcgccg gtctttcttt tttctagaat
    21961 caacgaatca gttatccgac tatctatcgg ctgttgatta tttgactttg atcaaatact
    22021 attggcagag caaagtagaa tgccaaactg ttttccaacg attgaagatg actgagtacc
    22081 ttactttgcc gattggaaaa atgtctctag gaatgaaaca acatgtcttg cttgctgctt
    22141 acttgatcag tgattcatct gtcatgttat tcgatgaacc gttgaacgga ttagacccag
    22201 gaagtattga tatcttgaat agcctcatca gacaatggca gaaagagggg aagacgattc
    22261 ttctttcttc ccacgctatc gcgaatatcc aatcgatttg ttctaaagca tgttttctaa
    22321 aaaatggaga aatcgtcaca gaatcctcaa atatggaaga gattttagct atttatcgta
    22381 aattatatga ggtgtaacta tgtctttact tacatttgaa cgcaatctct tactaaaaaa
    22441 caaagtaaac tttttatttc ctctattgtt ggtcgtgctc tttgcattcc cacttttttt
    22501 tgatcataaa cttgcttata cagaattcga tgaactgaat cataactatg aagagatgca
    22561 acgtttgatt gaaacgttga aagaagatga gaatgagaaa gaatttgtgg aaagtttaga
    22621 gaaaagcaac aaactgatcg aagcaatctt acatgcaaaa aacacaggga atgtccagca
    22681 aatggtcgaa gcaacttatc attatgaaaa agatatactg gatcgactga tttctggtca
    22741 aagacaagga attccaatca ttgaacaaca aaaacgtgtc gagttgctcc gttatatgaa
    22801 agaacatcag atccaaagat attctatttt tgacttgcca gcgcatctct ctttagcaaa
    22861 ttactacgaa aatatttttt caggaatgat ttctagtttt ttgattttat gtataaccgc
    22921 cttgtttctt tcttccatca tctcttatga aaaaagaaag caggtaatct ctctagtcaa
    22981 tctattaccg gatagtatgg taaagaaaca tagcatccgt tttaccattt attatggtgc
    23041 agctatgcta agtctcgtga tgccattttt gatcgtctct atactagtaa taatcaaaaa
    23101 tggtttggga gacttccgtt atcctgtagg aacgatcatt ggtcaggaga tacgaatcct
    23161 gccgatgtat gagtatcttt tccagagctt tctgttcctg ttgttgtggg tgctcttttt
    23221 aagtacaatc agttttcttc tatctgcttt atttgaacat tctctagtca atcttttagg
    23281 tacacttctt tgtcttttct tagcagagta tcgcttgttt tcttcgattg gatggataga
    23341 atcaatcagt cattacttgc caacttctta tgttgatttt caaaatgtga tcataggagg
    23401 agatattttc tcgccactag cttcagaaca ggttactttc atgaatggta tcttgacact
    23461 tggtatatgg agtatcgttt tattattcat aggtatgggc actatctata taaaaaagag
    23521 ctattaaaac acaaaaataa taggggcggt gacaaaaacc ttgtcaccgt cccctatttc
    23581 aaataaacgg ttttctagaa taaatagttt tcaaaagctt gcatccgcag taataagaac
    23641 ctcccaacaa aaatagctcc tcttattttt atcttggttg aagttattac ttgatgcaag
    23701 gcagcttttt ttactgtgaa cattggttat atatgtccat gttcaaaaat catttggact
    23761 tcttcaatgg tttccgcatc actgagcgcc attacttggt cgatgtctga acagaaaaag
    23821 gctaaatctt ggagcaccgc taactgatgt tcttttttta aagccactac aaataagagt
    23881 gtcgcgattt ttggttcctc ttttgttcca aagtccacac catcaggcac ttggactaaa
    23941 tagattcctt cttctactac ttcttcatct ttgtcagtcc catgtggcaa ggctacgaaa
    24001 ttcccgatat agacactcgc tttttcttgt ctttcgatca ttgattggat atatgccggt
    24061 ttgattcccc cttgttgggt catccactgg ccgatctcgg tcaacgcttc tttccaattt
    24121 tgataggatt gatcgagcaa tattttttct gctggtagct gtatcatctt ttcaccttca
    24181 tttctttatt tcttcaatca ggattttcgc taacaactga taaacgattt ctttatttcc
    24241 tgagcggaag atctcggtgt tcaagtcatt catgatgatt gctccactga tctttcctaa
    24301 aagaatcccg tctttttctt ggattggcga aggcgccagc ataactaaca tacgggacaa
    24361 atcgactggc tgtctatcca tcccttcaat ggtcaacgga tgtttcaaat tgaaaataca
    24421 aaagatcggt ttagaaatca atgagctgga tgtatggaat aaccccatat ttgtatgagg
    24481 aataccgata ggtgcttgtt catatcgctt aagcagccgg cgatgaacca cctcttcatc
    24541 cgttactagt ccttcaggaa aataaggaaa taagctgcga atcgtttcgg aaatcgtctc
    24601 aggattatcc agttcttgga taaaaaaacg accgagtaat tgattgattt gatccatgaa
    24661 atgcattgtt tcctcataag tatcttctat catccactcg ttattgctgt tatacgtaat
    24721 tttttgcctt tttttcttct caatatgcga aaaagcttct tttagctgct tgacttcatc
    24781 ttctagcagt agcggggaga ctaaaatata ttttccaccg tatcctggta aaatagatgt
    24841 agaaataaca acatcatatt cttcttgtaa atcgattttt tttaaatcag caatccgata
    24901 gaaatgaatt tgttggatga agggaaaata ccttttcaat cgtagttcca acatgctagt
    24961 agaagctaat ccacttggcg aaaatcctgc aatactgata ttgctttctt tcggacttcg
    25021 ttccaatgaa ttcgcaaaat gaaggaccat ataagcgatc tcttcttcgg ataatttttt
    25081 ttcttgaaaa atccgctcta ctgctttacg gattgcattc gcaacttcct cgtattgaac
    25141 catgattttt tctaaaatcg gattggtcag tgtctcttct tgtaaaacgg ctcttgaaaa
    25201 cacaccagat aaatgagtca acagcatttt gtacaaagtt tcatcttcat aaaaatggac
    25261 attcgtctct tcacttactt cttgaatcag ttgttttact aaataagcaa gctgtgtatc
    25321 gaacgtctct tcaaagaaat tctgatcaaa tgagttcgtg aagtcattta ataatcctgc
    25381 aaaaaagacg atctcattta ctggataaag ttgttttgtc tcagaagcga tccgtgaaaa
    25441 caatcgttta gctgtctgta gtaattcttt gtttgccaga ctattatatg tctcatttgt
    25501 cagtaaatga tttttcgtca cacgctccat cgtcaatgtc agcatcaaaa ccaaatgttc
    25561 aagctttcta tcacttagat tggtcttttt ttggatcaat tcttccccga ttactttgcg
    25621 tgcaagagat agatgttgcg gatcaacgaa tcgaaaaaaa taattcagtg atgcatcgaa
    25681 agaaatacta tgaaaaagtt catattcatt gatttctaat tctaatacat tcgctgtcag
    25741 aagccggcgg tatttttccg gtccttcgat ctcgtatccc tggttccgaa tgatttccaa
    25801 aggcagttgg cgaatacttt cttccaactg tttgatatct gcataaaaag tggtattact
    25861 gatgcgatat gattccatga aatgagcaag actcaacggc tctgtcgtca gtaacaactc
    25921 ggctaaaatc gcgtgttgtc gtttagcagt ggataagtca ttacttttcc catctgtatt
    25981 ttcttttaat tgctctaata cttcttctga tgcctcaatg acaaatgagc ctctagctgc
    26041 ttttttcaaa gaagcattta ccgatttcaa tgagacttca agattatcta attcgcggta
    26101 aatagtccgt ttactgacct tcaataaatt catcattttt tggatagata caggtgacgg
    26161 gctactgaga aattctgcta ataattgttt ttctctgggc gataaataca tcttatattt
    26221 ctcccttcac gagtttttcg tattcattcg tagctaccca atgttcaact agaactagcc
    26281 gagggatctt ttcttctagc tgttcagtta cagctagttc tctttgtgcg atataaatcg
    26341 tttcttcttg gattttgatt ttttctattg attcttttga gataacaaac tgttttttcg
    26401 ctttttttgc taattgactt aaaatcgtca tgcccatagt ttgtgagccg cgtctgttgt
    26461 ttttatacaa aaatacaata ttagcaggcg acgttttttg ttctgtgata tctgctatct
    26521 cttttttttc ttcccgcttt ggaaattgga tcgcttcttt tattcgtgac agcaagatat
    26581 ctgtttccaa aaagtgatcc agtacataga tttgactttg aggtactttt tctcttgcaa
    26641 gacccgctag ttcatgttgc acgataacca gctgatttac ttggttattc aattcataga
    26701 tagagctgta tccgacagaa agatcgattt tttctgctgc taatttcttt ttcagcaggg
    26761 cggctcccat agcacttgat cccatacctg agtcgcaagc aaaaatgacg gaatgaatga
    26821 tagatggttc caagatttct cccctttctt tgaccgtttt gttctctttt tctttatttg
    26881 gtaatttcaa tagtatcgct gcacaaatga aggtcacaaa tgtactgatt gctatcccta
    26941 tacttacccc agctagttgt ggataaggcg cattggcaaa aatcacgagt agtgacccag
    27001 gcgatacagg tgcagctaat cccgtatcta accattgaaa tatcaacgtg ccgcttgccc
    27061 caccagccat tacagctaaa aatagatacg gtcgcagcaa gacaaatgga aaatagattt
    27121 cgtgaatccc gccaatcgca tggatcatca atgctccact cgcatttact ttttcctgtt
    27181 tttctgcaaa acaaaggata gaaagtaaga tccctaaacc aggtccagga tttgcctcca
    27241 tcaaaaataa ggaagagtac ccgactgttt gtgagaattc gattcctaaa ggtgtcaata
    27301 caccatgatt gattgcatta ttgaaaaata gtacttttag aggttctaag atcagactga
    27361 caagtggtaa cagattcatt gtgactagcc aagacacaac ggaggcgagc aacaagtgaa
    27421 cactatttaa aactggttca ataaaaacga ttccaattat acaaataacg ctaccagtca
    27481 gtcctactag taggttgctg acaagcattt catatccagc cttgaatttc acatggaatc
    27541 tagaaacaaa ttgttcatat acgatgccgg caagcggccc gataatcatc gctcctacga
    27601 tttgtggagc attggaacga gcgatcaacc ctaaagaagc aattgcaccg gcgactgccc
    27661 ctttttgtcc ccctaccgat ttcccgcctg aataactgat caagatgggt aaaagcagct
    27721 ggatcatcca atggcatacc tcttctaatg tggtgtgcaa atcgccagac acaccttttg
    27781 ttgctaatga caagattccc caagcgataa acagacttag atttggcatg atcatttcat
    27841 ttaagtgatg tccagctttt ctcagttgtt tcatagacac gcgactgctg ttgtttgctt
    27901 tccatttgta ttccatcttt ttcaccagac ttctatttat tgatggacgg attttatgta
    27961 gaaaaagcag caaacgaaaa accgtctgct gctttcagct atctgggaac tatttgcctg
    28021 gttcagacgc aatgattgct agttcacctt ggaccgccca ctcagaaacg ccatttggaa
    28081 taatacagct tgttcctttt tctaatggat atgtttttcc gtcaacgaca aggtctcctg
    28141 ctccttcgat taccgtcatc aatgtataag gggcttgttt tttgaaagat gtgattcctt
    28201 taatatccca ctcatataca ttgaaaaact cagtttctaa ataagtgacg atcgatgaat
    28261 tcccttttcg gacttctttg atttgtaatt ctggtgtttt cgcagggaca gttgttacat
    28321 cgatcgattg ttggatatgc agctctcttg tttgtccttg cgcatctttt ctgtcgtagt
    28381 catacacgcg gtaagtcgtg tcagaacttt gctgtgtttc taaaatcatg attcctttac
    28441 caatagcatg gatcgttccg cttggtacat aaaagaaatc acctttttta actggtactt
    28501 tcttcaaaag gtcatcccag cgcccatctt tgatcatctc agctagttct tctcttgtct
    28561 ttgcatgatg accatagatg atttctgcac caggttcagc atcgatgata taccagcatt
    28621 cagtttttcc taattcacct tcatgtttca tcccataggc atcatctgga tgtacttgta
    28681 cagatagatc atcttctgcg tctaagatct tgatcaataa tggaaacact ggttctgaag
    28741 gatggccaaa caattccttg tgttctgacc atagttcatc taatcttttc cctttgaatt
    28801 cgccattttc tactacactg acaccatgag gatgcgcact gatcgcccaa tcttctccga
    28861 ttttatcgtt agggatatca aaaccaaaga ctgaacgtaa acgacttcct ccccaaattt
    28921 tttcttgaaa aactggtttt aaaaacatag gttcctgcat aattcaaact cctctcattt
    28981 ttcatagcta ttatagcatt atttcggtaa taccgctttc tctttcaaaa agttttcaac
    29041 aatttcatct cgacatatga gatactccgc acgatgatcg acaggatgta cgcgatttga
    29101 caaaaatatc aacgcttctt gtgtttttat atcaatcaag aaaaacgtac ctgtataacc
    29161 agtatgaaaa agaatcgcat gaccgtcttc tacatccttt tttaagtccc atcctaaaga
    29221 acgatagcca ttttttttcg gtgtttgatc ttgcagtaaa gaatcaatcg tctcttcttc
    29281 taaaaaacga ccattacgga tttttccctt gttcaaatac atttggacaa aagtaatgct
    29341 gtctttcaaa tcaataaaga gacccgcgtt acctgcatgt tcagccaaaa ctcttgcttt
    29401 cggatcatga gtttgtccac gcaaaacctc acccgaaggc agttgttctg tgggaacgat
    29461 ttttttggaa ggaaaaggaa gaaataagct gttcatcatt cctaatggtt ccaatacttg
    29521 ttcttgaaag atttccactg cagtttcttg gtaaatttcc tctagcatca acccaagaag
    29581 aatcgtaccg gcatctgtat attttacttc ttttcctagt tgctcacctg gttctagctt
    29641 caaataagcg gcgatcaatt cttcctgaga tagcttatct ctgtttggta tccatgtttt
    29701 gatatcagaa gtatgtgtca gtaaatgacg caaagtgatt gtctgatttt caaattcagg
    29761 aagatattta tgaagcggtt gatcgagttc tatctttcca tcttctaata gacgtaaaac
    29821 taatgaagtg gttgcaacga ctttcgtcag tgaggctgca tcaaacaaca gatcttctgt
    29881 catcagctgc ttttcaggaa cgacttgggc aaagccggct gtaaatgttt ctacttgatt
    29941 ttcttttatg aaggcgactg ctacacctgg ataaaatcct tcttccatct ttttcaaaat
    30001 aagctgtttc gtgtgtggat acatcttttt ctcctgcttt tctatcagat tcttacagtc
    30061 caagcttaaa gcttaatcta tgaggaatca acctttttta cacaaaaaaa ctgcgcgaaa
    30121 aaccgcgcag tttcccccgg tatactattt tctctttcta tctctagaat aagcgatagt
    30181 atgaccgttc ataaaatgac gagacatgcg acaatcgtta agaaagaaaa agttaagcgt
    30241 cgcatcgaat gtcagtttta ttcttttctt ttggctcact gacgaaccac cattcgattc
    30301 ctatagcatc atagattgtg agtactgtgt gctttttgtc taagaagaaa tcaactgata
    30361 gttgctgcaa gtgagcaatc agtccttcca tgctttcagt atcgatcatg aatttcagaa
    30421 aatcaagtcc aatcacttca tctgtaggca aatcaattgc gcctccgcta gcttctgtca
    30481 aaccaacatg gaaatctcct tcattcaata catggatgcc ctcttcttca ttatgtacct
    30541 tcaaaccaag tacatgatta agaaattggc gttcttttgt taagttagta acatttaaat
    30601 ggattttttc aaaataagaa cctgttgata gtttactgaa tttttcttca gattttctta
    30661 ataatgcttc ttgatccatt gtttctggaa tttctctttg gtcgttctta ttctcttcat
    30721 ggtaaatttc caattcattc tcttctgggt ctacgagcaa aatccccata cgtccatgat
    30781 cttctaaagc ttctttgatt ggataattca ttttacggat acgacaaagg atatctgcca
    30841 tttcttctgt gctagggata atcaatgaaa aacggttcag ctttttgatc acccccatgt
    30901 gatcattcgc tctaggactt tcttccagca gcaacatttc acttccagct tcttctgttc
    30961 ctaaaatggc taattcgttt tcttctcttt tcaaatcaaa gccaacaacg ttcttgtaaa
    31021 aatcaatcat tttatctcgg tctttcaccc gaatggctac actttttaaa taggtggcag
    31081 cccccaattg aaaatctttc atatttcttg ctcccctcta cgtcaagctt tattttaacg
    31141 atggattctt cttctttcaa gcaataactt tgattttgtt aaaaaaaatg tgagaaaatt
    31201 cgcattttgc ttgttttttg taaattaatg agtaaaaact cttataaaaa gaggttgtga
    31261 aaaagctgtt ctgcatcaag taataagaac agccaaacaa aaatagctcc tcctattttt
    31321 cgtttggttg ggcttattac cgcagatgca agcttttgaa caccgtttaa ggaagaggtt
    31381 gtgaaaaagt cgcttagttt cgagtagtaa gaaaaatttt gtgaaaatgg ctttctacat
    31441 ttttgcataa atttggctta ataccgagaa actggctttt gaacaccgtt taccaagagg
    31501 ttgtgagcct gccgtttaac tccgagtcac aaggagcaat ttcaaaaaac agcttctcag
    31561 gtttgttgac tattgtgact tgtgaccgag gagttggcag gagaacaccg tttaaggaag
    31621 aggttgtaaa atcagcggtt tgacctgagt attagagata caaaacggaa aaatagcttc
    31681 tcatattttg ccgttttttg agctaatacc gaaggacagc tgattgaaca ccgtttattc
    31741 ggaaaaaggg actgtgacac gacttttgtc acagccccta aaaaaaataa taaatttgta
    31801 ctattctatg aagcttcttc ttcagaaaac tgactgttat aaagatctgc atagaatccg
    31861 tctttttcca tcaatgtatc gtggtttcct gtttctacga tcgaaccatg attcatcaca
    31921 ataatgttgt ctgcatcgcg tattgtagac aagcggtgag caacaacgaa acttgtccgg
    31981 ttttccaata ggcggttcat cgctttttga atcagtattt ctgttcgtgt atctacacta
    32041 gatgttgctt catcaaggat caggacatct ggatttgcta agaatgcccg cgcaattgtg
    32101 attagctgac gctgcccttg cgaaatattg cttgcatcct cgtttaatac agtgttatat
    32161 ccttctggca atttacgaac aaaatcgtct acgtgagcag ctttagcagc ctcaatgatt
    32221 tgttcgtctg ttgcatcgtc gttcccatat ttgatattgt catagatact tcctgtaaac
    32281 agccaagtat cttgcagtac cattgaaaac tgtgcgcgca attcatcacg tgaaagatca
    32341 cgggtatcta caccatcgta acgaatacta cctccagaaa catcgtagaa ccgttcaaga
    32401 aggttgatca gtgtcgtctt ccctgcacca gtcggaccta caatagcgac catctcacca
    32461 ggtttgacat ccaagttaaa atcagtcatt agcaagttat ctggtgtgta gccgaattga
    32521 acattttcaa aacgaacttt gtatggtgta tctttttctt ctggaaggcc agatttttca
    32581 ttggacatct cttcttcatc caacacttca aatacccgtt cggctgaagc aactgttgat
    32641 tggatagtgt tcatcaaact tgcaagttga gtgattggtt gagagaactg tgttgtatat
    32701 tgcaagaacg cttgaacatc ccctaatgtc atgttcccat ttgcaacttt tactccgcct
    32761 agtacagcga cgaacacata gcctagattt ttaacgaaat tcatcaacgg catgatgatt
    32821 gccgaaataa attgagcttt ccaaccagcg gcatacagat tctgattttc tttttcaaat
    32881 acttcctggt ctttttcagt atgattgaat gttttaacaa tggtatgacc accatatgtt
    32941 tcttctactt ggttattcaa taaacctaaa cttttttgct gatctgcgaa aaacacttgt
    33001 gatttcggcg ctacgatcat cacgatgatc aagcttaaag ggatcatcaa taacgcgact
    33061 aacgtcaatt gccagctgat tgaaagcatc atcacgatga ccccaatcaa tgtgactgca
    33121 ctagttacaa attgagtcaa attttgctgc agcgtgcttg cgatgttatc catatcattg
    33181 attgctcgag acatgatatc cccatttgta tgtgtatcat aataggaaat cggtacacga
    33241 ttcattttgg cttccaaatc atgacgtaat tcataaactg ttcgttggga aacacgtgtc
    33301 ataataaatt gctgtaaaaa gttgaataca gcagaaatca aatacatcac gattactgtc
    33361 gcaatgatct gcgcgatttt atcaaagtct atcggaaatt ttgttacttg ttggccttgt
    33421 tgcatctgtt gagcgccagc cattacacct ttgaatattt ctgtggttgc tttccccaag
    33481 acctttggtg tttggatttg gaagatcacg gctgctattg ctagtacaaa tacagcgatg
    33541 atcgcaacca tacgtttaga catatagcca aacaatcggc gtaccgttcc ccagaaattt
    33601 ttaggctttt caccttttac accgagattt ctgccaggtc caccatgtcc tggaccgcct
    33661 gctggtccat gagagggacg tgtgtttgtt ttactcatgc taagtcctcc tctcttagtt
    33721 gtgaatgaac gatttcttga taagtttcgt ttgttgctaa tagttcttca tgtgttcctt
    33781 tgccaaccag ttttccttca tctagcacaa ggatcatatc tgcatccatt actgtactta
    33841 ctcgttgagc aactaaaacg gtgatacttt ctttcatatt cgttttcaat gcttggcgaa
    33901 gattggcatc cgttttgaaa tccaacgctg agaaggaatc atcaaacaca tagatatctg
    33961 ctgttttgac taatgcccgt gcaattgcca gacgctgtct ttgtccacca gagaagtttc
    34021 ctcctccttg ttccacatgg ctatctaagc catcttccat ctctgaaaca aaatctttag
    34081 cttgtgcgat ttctaatgct ttccaaatca tttcatctgt tgcatccggc ttaccatact
    34141 gcatattgtc tcggatcgtt ccagagaaca gaactgcttt ttgaggaaca aagcccatta
    34201 attctcgcaa attatattga gtcatgtcac taatgtccgt tccatttatt tggatcgaac
    34261 cagattcgat gtcatataat cgagggatca aattgactaa ggtcgtttta cctgaaccag
    34321 tcccccctat gattgcgacg atctcgcccg acttggcttg gaaatcaata tcttccaatg
    34381 caagtttttc tgctccatga tatcgataat tgacatgatt gaaggccaat gttgcgtttt
    34441 ttccagcaaa agaaactgtt ttaggatttt cagggtcatg gataccgatt ttttcatcca
    34501 acacttcatt aatacggtca gctgaagctt gtgcacgagg caccatgata aaaatagcgg
    34561 aaagcatcat aaagctgatc aagatctgca tcgcataagt cataaatgca atcagattac
    34621 cgacttccaa agtcatatct gctatgtagt gtccaccaaa ccaagtgatt gctacgtttg
    34681 taccgctcat gatcaatgtc atcattggca tcatcaatgc gacgatcgta ttaactttga
    34741 ttgccgtatt tgtataatct ttattcgcta aatcaaaacg attttcttca aagcgtgtct
    34801 tatcgaatgc tcgaatcact ctgacccctg tcaatccttc tcgaaatacc aggtttaaac
    34861 ggtcagtttt cttttgcata cttttgaata atggaacagc aaagtacatg attccgccga
    34921 tcaaaataat cattactggg atgacaacta agaagatttt tgtcaactga tgatcttttt
    34981 gataagcaag tatgctcgcg ccaatcaacg tgattggtgc attgatcatc atacgtaaaa
    35041 acatttgtgt aaccatttgg atttgagtca catcattggt cgttcttgtg atcaaagagg
    35101 ccgttccata tttatcaaac gcatcttttg tcagactctc tgatttttta tagacatccg
    35161 tacgcaattg cttacccagt ttctgtgatt cacgagtagc aaaaaatgta tttgcgatag
    35221 cagctaagat actgatcaaa gaaaagccga tcatcacaaa acctgtatgc caaatataat
    35281 cgacatctcc ttgcgctacc cctttatcaa taatattgga ggtaagtgtc ggcaaatata
    35341 aatctgccag tacttggatc accatgaaaa ctgcagctgc aattgctgaa gtcaaggaga
    35401 tccgttttac gatttttagc atctagttcc cttctttcta tttatatact ccgtttttca
    35461 gccaagaaag tttcaaattg aattcactga ttgcttgctc tactgagtaa tcttcagatg
    35521 ttgaaaataa gcgatacgaa tgcgcaattg ttgtaaatac agtattcatc actaattgga
    35581 tcagtaattc caattcatga tcatttttta ctttcagctt cgtccgatcg atcaattcaa
    35641 gcaactcttt tgcatcttgt ttgtgttctt tatgtggatc gtgaggcgtt ttttggcgac
    35701 tcgtatgagg agcgactttt cttgaggcac ggtaatccat gttcataaac aagttacgat
    35761 aaaaagaagc attctcgcct tccaaaatct cataaatcat tttagaaaaa taggattcga
    35821 atcctttgaa tagatcacca tcggattctt tcattagttg taacatatct ttagagctgt
    35881 cacgtctcat tgtctcaaag taataaaaat aaagatcctc tttatcttca aaatactgat
    35941 agaaactgcc tctagggata tccgctaatt tgacgatatt agcaatcgaa gcttctttta
    36001 agggtactct agaaaactcg attctcgcag cctcgattag tcttttttgt ttttctttag
    36061 gcaaatggaa aaatgtctgt gtcggcatat ggattctcct ttctttcaag atgacacatt
    36121 gtcatatgac gctatgtcat tataacacct cctacctgtt ttgcaagaca tttgcatagt
    36181 ttttttcatt atcatccgat acattaaaaa agtgataaga ggaatccttc catttgaatt
    36241 aatgagagtt gcccattaaa atagccacat actaaacaaa ggatgagata aatggcccaa
    36301 tcaattagtg tccaagactt caataaattg cctctcgatg ctgacagcat cgttttagat
    36361 acaagaaata ccttagatta cacaaaaaac cacttaagcc actcgctttc tatccccgct
    36421 gctatcttgc caagacaatt aaaaaatcta gatccaaaga aactttatta tattctaagc
    36481 tatacaggca ggcgatcaga agcattagcc gatcaactta ctgctaatgg ttttcgtgct
    36541 gtttatatca ttggtgggat ggaagctctt cagtcgagtg ttgcttgaat attgcttgtt
    36601 agattcaaaa gaggctgtga caaaaaatcg tgtcacagcc tcttttatac cctgtctttt
    36661 tttagttatt tattcttcaa ccttatcaat atgacttgat agccttttct ttttcgagta
    36721 aactgatttt gttagtcata gttataacaa tcatagcaat aaaaggagaa ggtaagcata
    36781 tggcatctgt tttagtagtc aaaggtcatc ccctaactgc agaagaatcg cgcacagtta
    36841 aggcattgac gtctttttta acaagttata aagaaaatca tccagatgat gaagtgactg
    36901 ttttggaact ttatcgcgat gatattccgg aaatcgatga agaattatta tcaggttggg
    36961 aagcattacg tgctggtgca gaattcactt ccttatcaga aagtcaacaa caaaaaattg
    37021 ctcgtttcaa tgaattgact gatcagttcc ttgctgctga taaaatcgtt atcgcaaacg
    37081 ccttatggaa tctaaatatc ccaacaaaat taaaagcttg gttcgatacc gtcaatgtag
    37141 ctggaaaaac gttccgctat acagaaaacg ggccagaagg attagtgaca ggtaaaaaag
    37201 cactgcacat ccaatctaat ggcggtgtat acaacggaca agactttgcc tctcaatatg
    37261 taaaaggtat tttaaacttt gtaggcatcg atcaagtaga tcagctattc atcgaaggaa
    37321 tcgattatga ccctgaccgt gcagatgagt tgatgcaaaa tgcattagat aaagctgctg
    37381 ctttaggtaa atcattttaa aaattgagat aaatgcatac aaaagagaca gaggaaaaaa
    37441 tcttcaaagc agcatttgtg ccttggatat tttcccatct gtctcttttt gttattcttt
    37501 ctgctttttc aacggatttt cttcataaag agaagagatt gttgtgtacc attcaaaaac
    37561 atgagtaatc actactttag ctgctgcata aacaggaatc cccaagatca caccgatgat
    37621 tccgaacaat ttcccagaag tcagcagaac taataaaatc gttactggat ggattgctaa
    37681 ctgattccct agtactaatg gagagatcaa gcgtccttct attgtctgct ctactgcaaa
    37741 aacgatcagt actttgatga tcatgaatgg acctgctaca atggctaaaa agatagccgg
    37801 aatcatcgct aaaaatgatc ctaagtaagg gatcaggttt aaaaaacccg caataatccc
    37861 caacgtgaca gcatactcta aaccaatgac cgcaaaacca atcataaaca tgattgccac
    37921 agcaaaagcc acagttagtt gtcctcttat ataagaagaa acttgactat tcatttcact
    37981 cagcacattc aacgtcggtt tttgcatgcg tgtcggtaaa aatttgacaa aataaggtgc
    38041 taattgttta ccgtctttca atagataaaa taagataaac ggcatcgtca gcagagccac
    38101 taaaatagtc gctaccgcgc cgacaaaact tccaagactc tgaactgtac tcttagatat
    38161 atcttggatc atatcgcctg ccgaattcat gaacttatca cctgctgttt ccaactgttc
    38221 gcgaaattgg ttgaacagcg ggtcccgcaa aatctcggtt aatttattat caatcgtatc
    38281 tacatattga gggaagttac tgatgaagct cactgtttgt tcctgaatct tagggatgat
    38341 cactacgctc ccccatgcga ttagtgcaac aaccaaaaca aacagcccaa tgatactgta
    38401 aagccttggt acttttcgct tttcaaagta atcaactacc ggattcatca agtaatacaa
    38461 gattcctgct aaaatgatag gcagacctac gattgctaaa aattgccaga ttggtgcaaa
    38521 caaatatgaa acttttgtaa ataaaaagac gatcagcaat attaacaata caacaagtaa
    38581 ggctgtgact acttgattat ttaaaaacca gcgccaaaac cacgataccg gtctgttctt
    38641 cttatttttt ccttccataa ttcctcctgt tagttataaa aaatttggct tcccaaacca
    38701 atagcaggca gtctatgcgg atgaagatag attccatttg caatttgtcc ttcttctgga
    38761 caagcatcaa aaatcaatga tacgtgagct actgtcttta aattcccatt ggccatcgga
    38821 ccgacataat cgatcgtata tacctgatca tcaaaagcaa ttgttccgcc tgctttcaaa
    38881 gaaaaaggtt cgtcttttga tacttcttga atcaccgaat attttcgtaa ggcagctgtt
    38941 gctgttttat cgaacaaaat cagcatgggt tcttccttgt ttattgcttc tgtcccaatt
    39001 tctgtaatct ttgcctgaat cattgcactc tctcctttaa ttgctttcaa aaacagtata
    39061 acacattctc attctttagc cgtgtggaat aattatgtga tagaataaaa acgaaaacta
    39121 tttcattaca attaggagga atcagctcat atgatcgaaa agataatttt aggaacctat
    39181 acgcgtcgcg aaagtaaagg aatctatacg atcgaccttg atacagaaaa agaagaatta
    39241 gccaaccttt cattagctgt tgaagaaaat agccctacct atgtagcaaa aagtaaagct
    39301 ggcaatcttt acacagttac tagtgtggat ggattaggtg gtgccggtgc gtacgataag
    39361 gattttcatt ttttgaatgc ggtaacagag tctggcgctc ctttgtgtta tgtagcggtt
    39421 gatgaagcac gtcaattact atacggggcg aactatcata aaggtgaagt aaatgtctac
    39481 catatattag gagatggcga actgaaagca gcagattcaa tattccatca agaagcgaca
    39541 ggtcctcata aaaaccaaga tcatgcgcat gtccactata cggatctgac tcctgaccaa
    39601 cgattagtcg tatgtgatct tggtacagat cgtgtgtata cttatgatgt gtccgaaaac
    39661 ggcaaattga atcttgtaac taccttcact gcagagccag gaacaggccc tcgccatctt
    39721 gtctttcatc caaatggaca attcgcttat ttatttggtg aattagacag cacagtccgc
    39781 gtgctttctt ataataaaga aacaggtgct tttgaagaat tacagaaaat atcgaccttg
    39841 ccagaagaat tcgacggtga aaatggaggg gcagctatcc gcatttcaaa tgatggcaag
    39901 ttcctttatg cttctaaccg aggacataac tcgattgctg tattcgcagt ttttgaagat
    39961 ggttcccaca ttcaaaacaa gcaaatcatc tcaacagaag gggattttcc ccgcgatttc
    40021 gcactagatc caagcaataa ttttgtcgtg tgtgccaatc agaacaccga taatctgaca
    40081 ttatatcgcc gtcatcctga aacaggatta ctggaattac tgaaaaaaga tgtctatgta
    40141 ccagaatgtg tctgtgttta ttttgatcgt tagtaagaaa aggagaatga aatgaatcag
    40201 caagacgtat tagacagact acgggaagaa ctaaatattc ctttctttga tgggaaaatc
    40261 gaagataaag agtatagcga agaggaatat cagaaactca aagccgattt acagaactac
    40321 tttgaacaat atgtacagaa tgtagaaaac taatcagctt tccatactat ctgaaaagaa
    40381 catcaggaca agacttttcc gtctatcctg atgttctttt ctacaaataa aaaaccgccg
    40441 agatggttag actcgacgga aaaggagtat ttactcgatt ttgagtaagt acaaggttgt
    40501 tgttggttat aggtatgtca ttatcataaa ggattttgat cactctatca taaaggtaat
    40561 attacattta tattagataa ctctagtttt tattgttatc aaagatttct tttatttttt
    40621 caacaacaaa ttagtcattt tttggatggc agctgtcaat tggtctgtcg cttggtcttg
    40681 ttttgcttca gatgtattga atagatcttc atctacccct gattcaagat cgatactttg
    40741 gatcatttct tcacagcctg ctacatatga aagataagct ttttcaaaat ttttatgaat
    40801 gcccattgct tttgctggtg gacgcaaagt actgactttc ataagcattg cccgatattt
    40861 ttttgttcct tcttcaaata acaggatgat ctcttcaaga gtcgatttgt ccagttcact
    40921 tgtttttcct tcatcaattg cgtttctgat cacttcatat ttcggatgca ttccttctcc
    40981 gattgcttct gtttccttga cgatttgatc gatggactgc acataatagc caatattcgg
    41041 taacatgttc gttttcctac tttctccatt gttgttatta tttattctac ttgtttttat
    41101 cctcaaatga caagtacttg aaaaaattta atggtttcta tacagctcgc cattcttatt
    41161 cgtgctcaaa gaaaccatct gctaaactat attgtttccc tgcgacaatg tcatattgga
    41221 tcaattgata ttcgtcgtaa atctcttgtt gcgagcgatt gaattgcgct tctttatacc
    41281 actgtccgtt ttgatagtac agttctcgtt caaacgccgg aagttcctgt tctaatgata
    41341 aaagcagctg ataaaagcca tttgttgtct gattcgtctg ttccattaga ttcgctgcaa
    41401 aataaaacgg actggtgatt gcatcgtgag tcgtttgctt ttctaattct cctttactgt
    41461 cgaacataag aaattgtgtt tcatgcaatg tttgtttgtc attttttgct tggatcgtat
    41521 ctgaatagat ccctggaaga tgatcccccc aaaaaacaac taaagtcctt ctagaaagat
    41581 tcttcaattc ttccgtgaac tgcttcagtg ccgtgctgct ataggaaata tcttgcagat
    41641 aattctctaa gtcaagtgtc ccacttccat ctgaagtttt tgcaggatag tctagattat
    41701 catactttcc atcgtagggc atatgtgtct gcatcgtgac taaatgaatg aactgaggtg
    41761 ttttttcttc cttgagaagt gtcattactt ctttgtaagc tgactcatca gaaatatatg
    41821 gattattctc tatcgtatcc gtataggtca tcgtacgctc gctgatgaac tggtcaaatc
    41881 ctaatgtctg ataaacatcc tctcttttat acatcgaagt attgtatgga tggatcgctg
    41941 tcgtctggta tgattgtgcg tttaacgctg aaacgataga aggaagctga tccatttttg
    42001 gtacaagcat cgtgtaaggg gtggtgagtt gcgcattaaa taacgccata gaaaaaccag
    42061 tcaatgcttc aaattcgata tttgctgttc caccgccata gttttgagaa agcatattgc
    42121 cactatatgt ttgatcagct acttcataat aatctgccaa tggctcacca gatacttcta
    42181 cgccgtttaa tcgactagga tctgagaaac tttcactcat cacgaacacg atgttcggcg
    42241 actcttcctc tacagtttta tttttttcat cggctagctt ctggtatttt tcagtgattt
    42301 ctttgatctt ttctttcgaa tatccttcag gttcatccat tggttctacc ttcagattgt
    42361 acaaaaaccc accgataaaa ccagtgttat agtagttcat tttctggctg taaggtatcc
    42421 atagtgccgt tttattatat gcttttcgca acaaattatc gggattgttg aaattactga
    42481 tataccctag cagtccaatt gccacaagca gtgtcgttaa tcggatcaat tggaatcgcc
    42541 ttcctttttt caggcttcga aacatgtacc agcaaaacaa tcctatcacg gttcctgcgg
    42601 cagctaagat cactgtaaac agcatagtgc cggtcatatc tttcagcaat ccgatttcag
    42661 tgatcatctt caaatcgtct ggataaatcg gttcttgccg ataactcatt ttcatataat
    42721 ttgcaaaacc taatacaccg atggctacga catacgtaag ggaacctaaa gggacagatc
    42781 ctgctagtgc aatcagaaaa ataagaataa tcagcaagac gagacaggct aagaagaatt
    42841 tttccgtatg ccaagaaaaa gcaaatttca acgcaaggtc tacggataga tcattttgac
    42901 accactgcaa aaataaatta ctaaaaacaa caagaaaaaa gatactgatg attgctgctg
    42961 ttccttttaa aatctttttc tgtttggtcg aaagtctgct tatatatctt ttcaaatgct
    43021 tgctccttca tttctatcaa taaaagaatg ttgcttctct tattttagtt gtacgaaatt
    43081 cgaaagtaaa gaacggaaag aagaattaat gaaatccaaa tattctcttt ctttatggcc
    43141 tttctggttt ctttaataag cggacctttc gtactccaga aattttttct agctgttgtt
    43201 tcacttgatt gagctgttca aaatcagtac tgtctatgtc aatcaatatg tagacatgct
    43261 cattcttatg gttacgcgat atatctgcga tcgctagctc gttctcattc agcagagaaa
    43321 atatctctgc taatatattg gttttctttt gataaaatat agtgaatcga aacggcgctt
    43381 ggaaaaacat tcgtgcggat ggataattga ccgcttctct aaccgtaccg aacaaaagat
    43441 aatcttttaa ggcttcaact gccaaacgtc cgctgtctgc caaagcttcc tgagtcgatc
    43501 cccctagatg aggcaacata agtatacggt cattttctaa gaactcttct tctggaaaat
    43561 cagtcaagta tttagccaga tgttgttttt ccaatgcttg cataacagca tatttatcaa
    43621 caatttcact tcttcctaca ttgataagta cagcatcttt tttcattttt tctatattcg
    43681 cctgatcgat caatcctttt gtatcttctg tcaacggcag catgactacg atgtaatccg
    43741 aggtagaaag aactgtttct aaatctgctt gccgaacata atccaactgg gcatcgcgga
    43801 tagaataacc caagacatcc atccctaagc tatagcaact tagcgctact tttgtgccta
    43861 tcgctccaag accaagaaga ccgatggttt tgccttgcaa ttctcgtccc acataagcac
    43921 ttcttttgtt ttctgcctgt tctaaaatat taggacctgt tagtgtttgt accatacgac
    43981 ttgcttcgat tatcggacgg gaagataaga gcaaacagca caaaacaagc tcttttactg
    44041 cattagcatt tacacctggt gtattcatga cgatcgtccc gttttcagaa gctttttcaa
    44101 cgttgatcgt gttcacccca acaccagctc ttgaaattgc tagcaaatct ggtgtaagcc
    44161 attcatcttt cactttcgta ctacgaataa ctattccttc ggctggcaaa tcatctatta
    44221 ttttgaaata ttccccttgt aacttttcta tctcttgttc tggaatagca tcaatcaaat
    44281 gaacgtgata cataaaaccc cctccttact aacaagtatc tcgaaatttc tgcaattaga
    44341 caactgttta ccatttgact tcctagaagc aaaaagagca gttagagcag agtaggctga
    44401 gtgataaaaa taaggctatg acaagttact gccataagcc ttattttcga gagcaaaata
    44461 ttgagggtga gatatcttga taaatggtgt tccgttagct gacattgata ataagactaa
    44521 atttcaaaaa agttgaaaag caaatttcgt caatctcttc ttatttctta aaactaagtg
    44581 gctttttcac aacctctttt tatctaataa ccactgtttc caactcaact aattttgccc
    44641 acgtttcaat ttgatctgtt gttagattta gcgagacaac ggtatgatga ccgccacctg
    44701 cctgaatcca tgaatggaca ccttcatgga aattcggttt agttttccat aacacacgtg
    44761 caacaggtaa attaggtgct tcagtcgttg gttcaaaggc ttctacttca ttgatcagca
    44821 gtttataatg cgtaccgaaa tctgccatcg atacgactac cccttctcct gctttcccat
    44881 caaatacaag acgcgccgga tcttctctat ctcccattga taaaggagaa acaacgattc
    44941 ttggtttcgt cgcagcaagc gtcggatcta cttccatcat atgggattcc aagattgctt
    45001 cttggccact agctagctcg taagtataat cttccatgaa tcctgtatct ttccctcgag
    45061 ccatgatttt cagcaaccga tcaatcgctg cagttttcca gtcgccttcc ccagcaaaac
    45121 cgtatccttc tgccatcaaa cgttgtacag ctagtccagg tagttgtttc attccataca
    45181 ggtcttcaaa attagtcgta aaagcgttat agcctccttc ttctaagaaa cggcgaatac
    45241 cgatttcctg ctgagcttgt acttttacat gttcctccca tgtcttttct tcataatcac
    45301 catagtcgaa ggtatacaat tccttgtact cttcaaataa ttgatcgact tcttcgtctg
    45361 atacgcgatc gattacttgt acaagatctc cgataccaaa ataatcaaca gtccaaccaa
    45421 attgaatctg tgcttccact ttgtctcctt ctgtgacacc cacgtttctc atgttgtcac
    45481 caaaacgagc cacttttatt ccaaaacttt cattataggc tactgcaaca tccatccaat
    45541 cagcaatctc tttttggatc tcaggtcgtt tccagtagcc aacgacgatt ttattttgtt
    45601 tatttaatcg agcattgatg aacccatatt cgcggtcacc atgagcggat tgatttaaat
    45661 tcatgaaatc catatcgatc gttttccaag gaatgctttc gttatattgc gtagctaaat
    45721 gaagcaatgg tttttgtaga agctttgtcc cgcggatcca catttttgct ggtgagaaag
    45781 tatgcatcca agtgatcaca cctgctactt cttctcgata attgacctct ttcatgattt
    45841 ttgtgatcgt atcagcagta actgctaatt cttgaaggcg gattggataa ggcaattggc
    45901 cattttcatt cagttcatcg accatttctt gtgcatgttt ctttacttct cgcagtgctt
    45961 cttccccata taaatgctgt gatcctacaa caaaccaaaa ttctttttct ccaatattca
    46021 acataattag ccactccttt tatttgtttt gtccgtaata cgcatttttt ccgtgttttc
    46081 gtaaataatg tttatctaaa atccgttgag gcagctcttc tgaaaatgaa ttgagctgtc
    46141 tggtaaataa attcatcttg catacttcat ctagtacgac tgcgttcatt accgcacttt
    46201 gcgcatcttt cccccaagta aatggaccgt gtccgtgtaa aagtacccct ggaattgcta
    46261 agggatcaat tttgcgttct ttgaatgttt ctatgataac ttttcctgtt tcatattcgt
    46321 acccgctgtc gatttcctgt tgtgtcaaaa atcgagcaca aggtaccgat ccataaaaag
    46381 tatctgcatg cgtcgtcccc atcgcaggaa catccaatcc tgcttgtgcc cagatcgtcg
    46441 cccatgtcga gtgagtatgg acgattcctc cgatttgagg aaatgaacga tataaaacag
    46501 catgagtagg cgtatccgaa gagggattga gtttaccttc aatgatatga ttgtccaagt
    46561 ccacaacgac catgtcgtct gctgtcatct cttcataact gactccgcta ggtttgataa
    46621 cgaaatatcg tgtttcagga tcaaaagcgc tcacatttcc ccatgtatat ttgacgagtc
    46681 cgtgtttagg caagtcaaga tttgcttggt atacttcttc tttcagttgt tccagcattt
    46741 tctatcactc ctttttcttg caattgatga atcgctgttt tttcaatgtc gatcccctca
    46801 cggtaacgtc tcataaatat ctgatagcct gctatttctt ctgctgaagg tgtgatggtg
    46861 attccttggt cttgtccaaa cacgtcttct gccaagaagt tttctaaaga cttcccatgt
    46921 cgatccatca tataggctgc taataacgcg attccccacg ctccaccttc tccggctgtg
    46981 tccatcactg taactggtgc ctccatagca gatgctagaa tccgctgtcc aacttctggt
    47041 gttttaaaaa tccccccatg ccccactaaa cgatcaattt ggacattctc agatttcaat
    47101 atatccattc cgattctcat tgcaccaaaa gcactggcta aatggatccg catgaaattc
    47161 gctaaatcaa aacggctacc tggtgtacgt acaaataatg gccttccttc atttactcct
    47221 gtaatgtttt caccggaaaa ataaccataa gaaagtaatc ccccgcaatc cgtatcgcct
    47281 tctagcgctt tgttgaataa taccgtgaat aatttatctc tgcttatctc catacccaaa
    47341 gaattggtaa attcttcaaa aatactgacc caagcattga tatccgaaga gcagttattc
    47401 gtatgaacca tgcctactag ttctcctgaa ggtgtagtga ccatgtcgat ttccggatgg
    47461 acattttcta gttctttttc taatacgatc atagcgaagg cggaagtacc agccgaaatg
    47521 ttccctgtcc ctttggctac actgttcgta gcgaccatac cggttcctgc atccccttct
    47581 ggcggacaaa ccgggattcc tggtctcaaa tttcccgtag ggtcgatcag ataagcccct
    47641 gattcgctta acttgccagc ttcttctcct gctactagaa ctttaggcaa aatgtgatcc
    47701 aagtcaatcg ctacgtgcgc tttttcgatt aactgaccaa aaatattttt catttcttga
    47761 tggtaggttt tcgttgaagg atcgatagga aacatgcctg atgcatctcc tacgcctagt
    47821 actttctcac cagtaagctg ccaatggaca taacctgcaa gcgttgtcaa aaaattaatt
    47881 tctttcacat gttcttcttt attcaaaata gattgataca aatgagcgat actccatctc
    47941 tgcggaatat tgtattgaaa tttttccgtt aatattcgtt ctgcttcttc agtgattgta
    48001 tttcgccaag tacgaaatgg tactagtaac tgttccttgc tatcaaatgc tagataaccg
    48061 tgcatcattg cactgaaccc aatcgacccg attgtcgtaa gattctcgcc atagatttcg
    48121 aatacttctg ctgccatttt tcggtaactg acgcgcagtc ctttccaaat atcttctaat
    48181 gaataggtcc agataccatt ttctagtttg ttttcccact cataactacc agcggcaata
    48241 ggagtaaaag atgaatcaat caatacagct ttgatcctag ttgatccaaa ctcaatccct
    48301 aaagatgtac gaccatctat gacatctaac atactttgcg catttacttc cttcataatg
    48361 atttaactcc ctccttctcg tcaaacctga tcaaaccgtc tttttagtag cgcttacaat
    48421 gattattgta tacttttgta cgtacatgtc aagcagttat ttacaagaat acaataaaaa
    48481 acacttgttt tgtacgtaca taagttataa aatgaaattg cttacaaaat ctgatcaacc
    48541 gccttctcga aattctagaa ggagagaata cttatgaaaa aagaaaaaaa agtttcctca
    48601 tcgtttattt atttttttgg cgcatttggc ggcattctat ttggatatga tattggtgtt
    48661 atgaccggcg ccttaccttt tttacagcat gattggggtt tggcaggtaa agcttctttg
    48721 ataggatgga tcacgtcttc ggtcatgtta ggtgcgatcc ttggcggctc tttatctggt
    48781 cttctttctg ataagcttgg acgacgaaaa atgattcttc tttctgcact tatttttatg
    48841 gctggttctg tcctttctgc atctgcccct cacaatggtt cttattttct gattgcagca
    48901 aggattcttc taggtttagc tgttggcgct gcatctgccc tagttcctgc ttatatgtct
    48961 gaaatggctc ctgctagact aaggggaaga ttgtcaggga tcaatcaagt gatgattgct
    49021 tctggcatgc tcctttccta tgttgcagat tatttgctaa aagggttgcc tgaaacgatg
    49081 gcttggcgcg tgatgttagg gctcgctgct gtccccgcgc tgattttatt tttcggtgtt
    49141 ttagctctac cagagtcacc gcgttttctt atgcaatctg gccgcttgga agaggcaaaa
    49201 agagtattga actatattcg gacaccaaaa gaagctgaac aggaattcga acaaatccag
    49261 ctgaatgtca aacaagaaaa gacaaccgga acttcttggc atactttgtt tttagaaaaa
    49321 tatcgttcct tagtcattgc cggtattggt gtagcagtat tccagcaatt tcaaggagct
    49381 aatgctattt tttactatat tccgctgatc gtagaaaaag cgactgggca tgcagcgagc
    49441 gatgcattga tgtggccgat catccaagga atcattttag ttgctggttc tttgctcttt
    49501 ttggttattg cagacaagtt caatcggcga actttattga aaataggcgg tagcgtgatg
    49561 ggactttctt tcatcctacc agctgtttta ggaactgtac tggatgctca tacaaattcg
    49621 ttgttgattc tcttgttttt atgtatttat gtcgcatttt attcttgcac atgggctcca
    49681 ctgacatggg taatcgtagg cgaaatattc ccactagctg tccgcgggcg agcatctggc
    49741 ctagcctctt cttttaattg gattggttct ttcctagttg gcttgctttt tcctgtgatg
    49801 actgcttcta tgtctcaaga aatcgttttc ggcatttttg ggatcatctg ctttttaggg
    49861 gttttattta ttcaagagat cgtaccagaa actcgtggga aatctttaga ggaaatcgaa
    49921 caaagtgcat ctaaaaaaac ttatcctaaa cgtatttcta tccatcattc ttaaagaggt
    49981 tgtgacagaa gtggtcagct tcaagaaata agaaggaacc gcttagtttc cagtcacaag
    50041 gaacaatttc aaaaaacagc ttctcatgtt tgatgaatat tgtgacttgt gaccagttgg
    50101 taggagaaca ccgtttagtg gagaggtggt gaaagaaacg ttcagccttg agcgatgaca
    50161 aaagctctca caaacattgc gacgagtaac cgtaggagca ataagaggcg gtaaaaaccc
    50221 gtctcttatt tttcgttttc tttcactgtt tcccgttcaa ctagtacagg ttcatagaga
    50281 atatttggct gtgcctgtcc tttttcaatc gttgtgacga tccaccgtgc ggcatcttgt
    50341 cccaactttt cttttggatg cgtcaatgtt gtcaattttt tattccctaa atggcttaaa
    50401 gaagaatcgt ctgttcctac gatcgatagg tcatctggaa tatgatagcc attttctgtc
    50461 aacttatcta gcattaaact agctatttga tcgttatagc aaatgatgcc atctaaagct
    50521 tgttcttctt tcaaccgttg tactgttttt tcagcgattg tttctcgtgt ttccgtggtg
    50581 aaagtaatga tatcttccgt caaaaaacgc acattatact gttcacacgc gctgataaaa
    50641 cctttcatcc tgtattttcc ttgaagatcg tcgatttttg tgatgaacaa cagacgctga
    50701 tgtccttttt ttatcaaata ttctgctgcc ataaaaccga ctttcacatc atctaaacaa
    50761 atataagagg catttaactc ttcataagca gcattgatca tcaccatcgg aatgccttgt
    50821 tctctcaaag caacataaag tgctaagttt gggttatact gattactttt cgtaggctca
    50881 acgatcaaac catctacccc ataagcaatc attttcttca aacactcttt ctccaattcg
    50941 tgatcgttat tcgtactggc taaaagcaat gaatacccag attctcgtaa ttcattttcg
    51001 attcctcgga taatcgacgg aaaaatataa tcagagagat atgtggtgat gacaccgatc
    51061 gtttttgttc tgttcaatgg tgttttttct ttcttatagc tgtcatctac atatgtgccc
    51121 gacccttttt ctttacgcag atagccctca tttaccaaca cagcgattgc ttgccgaatc
    51181 gtatgtctgc tgacgtcata tatttcttgc agcttgaatt ctgagggaat ggttgtattt
    51241 acttcgtatt cctcacgaag gatcttttgt tttatctctt ctgcaatatc ttgatatttt
    51301 gccatttgcc ttgccccttt ttatttgtac gtacatatat cataacgagt ctgcaaggtt
    51361 tattcaagca aaaatcaagg tttcttgtgc tcataaggca tacggaacag gttcaccaaa
    51421 ttctggaaat ccttgctcat tccacgtaaa gcattgcgcg ttcgcgtgcc gattaggatt
    51481 gtctaacgga tccccttttt ggttcttctc tggtcgagca tgatagatca aaatatcaaa
    51541 gcacccgtct tctgaaaccg taaacgagtt gtgaccagga ccaaattgct tatttttttc
    51601 agaagaaacg aatactggct ccgataattt atgccatgat tcttttaata aaagattctt
    51661 gtgctcatca gcccacagca ggcccatggc atagttttca tctgttgcac taccagaata
    51721 cgtaatgaat attttcccat tgcgagtaag gactgctgga ccttcattta ctgaaaaacc
    51781 ccgtttttcc cattcatact caggtataga aaggaggatc tgcttcccct ttaacgtcca
    51841 aggattatcc atttcggata gataaagatt agaattccca gtaatttcag gatcttgttg
    51901 ggcccacaca taatatagct ttccttgaga agagaaagtt gttccgtcta aactgaaagt
    51961 ttcccttttc gtttttattt gtcccttttc tatccaatct gtattcattg gatctatatg
    52021 ctgattttca agtacgaaca tgcggtgatg atgagattca tcacgtatag ttttatgatt
    52081 gcttgcagca aagtaaatat accattttcc attgatataa tggacttcag gtgcccagat
    52141 caattcactc atcggtcctt cttcatgagc ctgccataca atcaggcttg cagcatgttc
    52201 taattcattc agtgactttg cccttcttaa ttcaatcact tggtagcctg gaaccgatcc
    52261 tgtaaaataa taataaccat ctgtatgttt atatacccaa ggatctgccc gttgccgaac
    52321 gataggatta ttataaagtg tcttcatcat aacaaatttc ctcacatttt ctttattcta
    52381 attacattcc aagagtattt ttctatccct acatttaatt cgtcatgttt ttctattgaa
    52441 aaatagttta tttcaggttt tattttttct ggttcttcac gtgtattttt gtccaacaga
    52501 tcgctactgg ttaatgtgta gtgctctcct tgatctagca aattgaaatc atgttcaatc
    52561 gttatctttt gttgttcatt tgtgcgattg atcaagaaaa tagtcagctg attgccgtta
    52621 tctacgatca cactgtccac ataaggaaca ttttttatct tttcacaatc ataaacaggg
    52681 caaatgattt gttgtttcaa tacttgacct ttagcatatt tcgataagtg ttgcatcaca
    52741 taataagttg gattcctcca tgcttgtcct ttagcatctg tcagtattaa aggtattgtg
    52801 tttactaaca atgattgaca actaatcttt acgcgatctg cgtgtcgtaa aatagccagc
    52861 cctaatgaac caaataataa tgtatcttcc atagtaaagt aacaccaatc gatgggacta
    52921 ccgacttcaa aatccctatg tcttttttcc ggttgggcat gtacattcca ttcatcaaac
    52981 gctagataca ttgttttctc acttctcaaa tatcctttta cataatcaca agtagcaacg
    53041 atttcttcaa tttgacgatc gaatcgataa gcttttgcaa ggtatgtcgc tgtatcatca
    53101 cgctcatttt taggaggttt agtcaagtct tcttcatcat acttatcaat atagttatgc
    53161 aaagctaaat aatctacatt ctcataagct tcttctaatg cgatacgatc ccattcaggg
    53221 tacgatggta aacgtggcgt agagcttcca actaagattg tttcaattga atcatccact
    53281 aacttcatga cttttgaggc ttcatttgct aacctaccat attcataagc actcttagcc
    53341 cccacttgcc atggaccgtc tagctcattc cctaaacacc ataatttaac gccaaaaggc
    53401 tttttttgcc cattttttat tcttaaatca ctccagaagg ttccttttgg aaaattacaa
    53461 tattctacta aattttttgc ttcatcaatt ccttttgttc ctaaattcac cgtgaatatc
    53521 ggtttcgctt gtacatgact gatccattta aaaaattcgt ggagtccaaa agaatttggt
    53581 tctatacctc gccatgctaa atcaattttt tttggtcgtt gttctttcct acctacagta
    53641 tccacccaat cataaccaga tgtaaagttt cctccaggat agcgaatgac acctaattct
    53701 aattccttta cataagagag gacatcttgt ctaaacccgt caccatcagc tgtttcatgg
    53761 cccggttcat aaatccctgt atagacgaca cttcccatat gctcaacaaa tgagccaaac
    53821 agccgagaac tgatctctcc taccgtaaaa tcctctctga tttttacttt cacttcttcg
    53881 tccaacagct ttccctacct ttcatttcct atagtcaaga taatagatac aagtttccat
    53941 acgccaccag caaagataaa aataaaagga gggaaaagaa atatgagcag tacaaatcct
    54001 aataacaata cgcaacaaag aatatttctc aaaaaatcaa aaaatacttt ccatgcactt
    54061 tgttcaaaaa tttgtaaaaa tgtgatatct ttgttttcag aaatcacata tatccaggat
    54121 aaaagaaaca tggaataaat aagtaaaact acatatccac taattgaaag tacgattgtc
    54181 tgttcttcta ataattgatt aacaagaaaa taaataatga tcgttaacag actaaggaac
    54241 aagttcttac caaaatgttg ctttattcct tgaaagaaaa aataaatgat atttcctgat
    54301 ccctcacctt tccattgcgc cattacataa aaaacagcac atgtagcagg cacgatagta
    54361 ataacaggca aacacacgat tacccagaga atacctaata agatgtaatc agaaaccaca
    54421 atcaactgtc cataaagttt agtctcaact attttcatct tcctcactct ttcattccag
    54481 acatagctgt tccttgaaca aaatatttct gtgcaaaaat ataaaccact agtaatggca
    54541 gcattgaaat aaccgttcca gccattacag gtccataaaa agaaatgttc tgccctgtaa
    54601 ataaagctaa ccctgctggt aaagttctca tttttgaact acttgtcaat atcaatggat
    54661 aaagcaagtc attccaacta ttcatcagcg tgaaaatccc taatgataaa agagtaggtt
    54721 tgctcaatgg caacatgatt ttcaaaaaaa tattaaactc acttaatcca tcaatgcgtg
    54781 ctgcctcttc caaagaatct ggtaaagtaa taaaaaagga acgcatcatg aagataccaa
    54841 atgcagttgt catacgagga atgatcaaac ctgcataagt atcaagcatg ccaagcaaat
    54901 tgacttcaat aaatagagga atcatgaaga cttggaatgg gatcatcatt gtcagcaaaa
    54961 cgaaatagaa caaaactgat tttcctttga aacgcatacg agcaaatgca taccccgcaa
    55021 gagaatcaaa gaatacagaa gtgatcactg tccctccagc aaaaatcact gtatttttga
    55081 tgtaatctaa taaagggatc gttgtccaaa ccttaatata gttatctagg gtatagctat
    55141 ctgcaaatat tctaggcgga aatgagataa tgtctttttc gtgtttaaaa gaagaaataa
    55201 tcagccacaa aaaaggaaac gcaataacca acaatataac tagcatacta atcgttcgaa
    55261 tgattttttt accactaact gcttttcgac tattcacagt aactgtaatc gagctttctg
    55321 gtgccataca ggtttccctc ctatttcatt tgtttttctt tccgtgacat gtacacatta
    55381 gtggagatag ctatagttgc aacaatgata aacaaaaccg aagacagtgc tgatgcatag
    55441 cccaattcat aaggtgctgt aaatcctcga ctgtaaatat attgaacagc tgtttctgtc
    55501 ttaaattgtg ggccaccagc ggttgcaaca tatacttggt caaacacttg catcgaacca
    55561 atcagattcg ttaaaataca aaaacctaag gagggaacga tctgaggtag cgtaatgtta
    55621 aaaaactgct gtcgatttgt tgcaccatcc atttgagcag attcatacaa agagggagag
    55681 attccctgaa tagcagtcaa gagaatcgtc atagtaacac caaaattctt ccaaacagtc
    55741 atgatggcta ccgtcggcat agcaagggtt ggatcgcgaa aaaattgagg gatcggcaag
    55801 ccgacttgtg aaaacaagta aggaatcgcc cctacattcg gatcaagcaa catagaaaaa
    55861 ataatcgcaa ttgacgtcaa tgaacaaata actggaatgt aaaatgtcga acgacaaaaa
    55921 cgattgaatc tggtattttt agataatgct actgctgcta ataaaccaac gataatttgt
    55981 gttggcgttt cgagtacggt gaaatataaa gaatgaatca acgaattaac tgctcgttca
    56041 tcactaaata tacgtgtgaa attttcaaaa cttacaaaat ttcttgatgt aaagaaaata
    56101 ttcaaatctg taaaactaat agcaaatgtt cctaaaagcg gtatgacagt aaataataat
    56161 aaaactaaaa aagatggagt taaaaacaaa tacgcagcac gatcaggacg attccaatat
    56221 ttggtgaatc cgttcatata gtccacctca tctttcattt tgataaaata tacaatcttg
    56281 gtttaaacga atctgaataa gatatccgaa caatcgctgt gatttttgca ataacaccta
    56341 tctgcaaata ctaggtcgat cattcagata tctgtatctt gccaacagtc tatcctgtat
    56401 aaagttctgt actatttttg cagtaattga ttgatggcat catctgcatc gttcatgagt
    56461 gtctcaggat cttctcctgc taataatttt tcaatcagtg gattgatgat atcgttattg
    56521 atcgcagaga tttgggtaaa acctggtaaa tatggctctg catagtccat ttgtttcgat
    56581 aattcagata caataggatc attttttact tcttcatctt ttgctactga atccaagtag
    56641 gcaggaaaac cattttcgat actccatttt ttaccaattt cagttgtatt ccaatatttc
    56701 aaaaactcat agacagcttc ttttttatta ttatctgtac ttgccggaat ggcatatcct
    56761 acgccatcta aaatagctgt ttttttgtct gaatcactcc cttgtggtaa ggtagtcaca
    56821 ttataatcaa tctcgtttgc tttcaatccg ttatttaacc atggcccatt gatttcaatg
    56881 gctagttgac cagcattcat taaattgtcc atttcggcgc cagaaatcga ttctggacca
    56941 gtcttgtcta catggatcat tttttggatc gcttttaacg ttttaaggtt ctcaggagac
    57001 gcaaattcag acttagtata atcatcgttc actaatttac cgccatttgc taacatccag
    57061 ttatataacg gtgcagttcc atccttattg aagacaaaac ctgatacatt tttactacta
    57121 tcagttaatt ttggtgccat ttctgtcaat tcttcccaag tagtaggtgg ttgttcagta
    57181 tctaatccag cttgtttaaa caaatcatta ttccaataca tatacatgcc ttgtacctgc
    57241 atggggacaa aatactgttt accttctact tcacctaatt caatagccgt ttctttaaaa
    57301 tcagatttat ctactccatc atattcccag aaatcgtcta atggttgtac cgctccgttt
    57361 tctacatact gtgcaaaatc tggataattt aatgcaataa agtcaggtgc ttttttagaa
    57421 gaaatcgctg taggaagttt ttcattcaaa ttggcccaag tcatgatatc catttcaatt
    57481 ttgatgtttt tatcatttgt tttattaaat tcattaacga tttcttgcaa tatttcacca
    57541 tcagatgcag taaacccatt ccaaaaagtc aaagtcactt ctttatcaga atcagattct
    57601 gctgaacttc cgccaccgca agctcctaaa atacctgttg cagctaccaa caaagagcca
    57661 attaaccatt ttttaccttt cattttttgt tcctccttca tctgataaac gacatctgac
    57721 cacattccaa gatagcggtt tcaataaaca attgattttc ccatcttcag cttttacatt
    57781 tgttgaatga cttggtttta cttgttcact tttaggaaga ttagttgctt ttgtatcaaa
    57841 tccactcatt tcagaaaaat caatcactcc ctctaatgat aattcagaca agtgaacagt
    57901 tagattcatt tcttcttctc cacggttaac tgcaaatatg acaagttctt tgtcatttat
    57961 tacggctata ctttctaaat acggcacttc ttcaaaatct tccgtcgcat agtttgctga
    58021 acgaatttgt gggcttaaca cctctccttg tccatacaca gcagcttgca taaatggata
    58081 atagatcgtc tgtctccaag cttctccgtt tgtttctgtc ctgattggtg caataacatt
    58141 taccaattga gcaagacaag caatctttac tctatctgca tgtttcaata aagtgattaa
    58201 tagacagcct aatagtaatg catcttcaaa attatagtta tcttctagta aaggaggagc
    58261 aatctgccaa ggcgctgctt gctcatcttg ttccgctgaa tgataccaaa tattccattc
    58321 atcaaaggac aggttgatct gcttcttact atgtttcttc gccttgactg tatcgcacat
    58381 cgctgtcact tcagaaatga accgatccat gtctaaggaa cgtgcaagat aatgagaaag
    58441 atcatttttt tggttgccat aatattgatg cagagacaaa taatctattt gatcgtacgc
    58501 ttgatcaaga actgttaact cccaatcacc aaatgtaggc atttgccgat tcgaacttcc
    58561 gcataaaacc acctcaattg aatcatctac gagtttcatc gccttagccg tttcctctgc
    58621 taaccgtcca tattcttccg ctgttttatg tccaatctgc caaggaccgt ccatttcatt
    58681 ccctaaacac catgtcttaa ttccaaaagg gctctcttga ccattcgaac gccttaaatc
    58741 actccaataa gttcctttag gaaaattaca atattcgact aaattacgag ctgcatctac
    58801 tccacgagta cccagattga cagccatatt gatttcggcc cccacatgct gacaccagtt
    58861 ataaaattca tgaatcccaa cttcattcgt ttcaattgtc cgccaagcta aatccaacct
    58921 tctaggtcta tttgctatgg gcccaatact gtcttcccaa cgaaatcctg acacaaaatt
    58981 tccaccagga tatctaatca tgggaatgtt caattctttt accaagtgaa tgacgtcttg
    59041 gcgaaatcca cttttattag ctgatggatg atctggctga taaatccctt catatactgc
    59101 tcgtcccata tgttcaataa atgaactgta caaccgcgga tcaactttgc ctacacgctt
    59161 gacactacta atcaacattg tggcttccat aactgacctc ctttaattta tacatgaata
    59221 atacacctcg ttgaaagcgt tgtcaataat ataaatgtta aacttactta ttttttatcg
    59281 attttaatta accaaaatat taataatgat taaaacaaat aatttaatat aacttttatt
    59341 aacaaatatg ttaatatata agaaaaacct tttaagaggt gatatatatg caactacaaa
    59401 taaacgaaga atccttaccg gtatatgaag cattagctag taaaacaagg atcaagatca
    59461 tccagctact ttccaaaaaa aagatgaatg tcaaagattt ggcaaaagaa cttggagtga
    59521 gcagtgctat cacgacgatg cacgtgaaaa agctagagga agcaaacatc atcaaaacag
    59581 aaaaagtagg acaacaaaaa atttcgagcc ttcgtgtcga taaaatcgat atcagttttc
    59641 cagaaaaaat attcaatgct tttgatacga aagaaacatc gatacctatt ggtcactata
    59701 caaattatgc aattgaacca acatgcggtt tagctacgat ccatgatttt atcgggaaag
    59761 tggatgaacc acgctatttt atggatcctc gaaggatgga tgcccgcatt ctctggttta
    59821 ccagcggatt tgtcgagtat caggcaccta attttttaaa tacagaggat acattggaga
    59881 tgttggaagt ttctgtggaa atttcttctg aatttccttt ttcaaatgac aattggcctt
    59941 cagatatcac tttcagccta aatggtgtgg agctaggaac atggacgagc cctggagatt
    60001 ttgctgatat ccgcggtaaa tatacgcctg attggtatcc agataatctt aatcaatacg
    60061 gcttgctgaa gacgatccga attaccaaac acttgacgaa tatgaatgga gaacccttgt
    60121 caaacatcac gatcaacgac atccctaaag agcaagacac ttggcatttg cgaatcgaag
    60181 tgaaagacga tgccaaacat gtggggggct gtactttatt tggtaaagga ttcggtaatt
    60241 acgatcagga tatcaaatta aaagtttact acagctgata tttttctttt ctattttata
    60301 aaacaaaaac agccaatccc tatgaaggga cggctgtttt tgctttattg ttatttccag
    60361 aaatcatcca aaacggaaat tggcaaatgt cgtttatgtt gtgtcttgtt ccaccatgct
    60421 tcgatttttt cttgtgcttg agcgggaact tcttttcctt ctagataatc atcaatttca
    60481 ttatatgtga cacctagtgc gacttcatct gcaatcattg gtttcccatc ttcaagatct
    60541 gcagtcggaa tttttgtgta taatttttcc ggtgcattca atgcttgaag caattgtttc
    60601 ccttgtcgtt tgtccaaacg gaataatggc aaaatgtcgg ctccaccatc accaaatttc
    60661 gtgaagaatc cagtaatgtt ttctgcagca tgatctgtcc ctaatacggc tcctgctctt
    60721 tctccagcta cggcatattg cgtaatcata cgttgacgtg ctttgatatt tcctttgtta
    60781 aaatcgctga ttcccacacc tgcttcgctt aatacttgta cttgtgcatc aacagctggt
    60841 ttgatattta ctcgcagact aacatcgggc tggataaagt caagagcagc ttttgcatct
    60901 tcttcatctg cttgttcacc ataaggaaga cgaacagcga taaattgata gttttcatct
    60961 tttgtttctt cacgcatttc ttccatcgtt agttgcgcca aacggcctgc taaagtagaa
    61021 tcttggccgc cgctgatacc tagtacaaaa gttttaagaa acggatattt tttcaaatat
    61081 gctttcataa agtcaatact tttacgtatt tcttcttttg gatcaattgt tggtttgaca
    61141 cctaattcat tgataatttc tgtctgcagg ctcatttatt ctcctcctat gcttctgtat
    61201 gaagttctgc tacgcttttt ttcattcgtt ccatgatagc cattttatgg ttccagcatt
    61261 cagtagacag atcgactggg tatttttgcg gattcaagtc tcgtttatac tcttcccata
    61321 gtgaatctag attttctttt gtatattctt tgatttcgtt tagtgcaggt aattcgtaaa
    61381 ctctttttcc ttcgataaag atatcttgta aaactgggcg agctgtaaag tctcgaacag
    61441 ttttattgat aaacgtatgc actggatgga acatgaagat agcttcttct tctcgagggt
    61501 cttcatccca taatgtcacg tagtctcctt cagatttccc atcaaaattt cgagtgatgc
    61561 gccacacttg ttttttccct ggagtagtta ctttttctgc attgcttgat aacttgatcg
    61621 tatccatcat ttttccttca tcatcttcga tcgatactag cttgaatact gcaccaaggg
    61681 ctggctgatc ataggctgtg atcaattttg tcccaacacc ccatacatca attttagctt
    61741 tttgcatctt taaattcaaa atcgttgctt catccaagtc attcgaagca tagatttttg
    61801 cttccgtaaa tccggctgca tctaattgtt cccgaacacg cttagatata taggccatat
    61861 ctccactgtc gatgcgtacg ccttggaagt tgattttgtc acctaattct ttcgccacgc
    61921 gaatcgcact tggcacacct gatttcaacg tatcataagt gtcgactaag aacacgcagt
    61981 ctttatgggt tttagcgtag gccataaatg cttcataatc atttccataa gattggacta
    62041 acgaatgagc atgggtcccg ctagctggta tcccaaatat cttcccagca cgtacattgc
    62101 ttgttgcatc tgctccgccg atatatgccg ctctagttcc ccagactgct gcatccagtt
    62161 cttgtgcccg tctagttcca aattccaata gtggatcttc tccgatgaca gatttgatac
    62221 gagctgcttt tgtcgcgatc aacgtttgga aattgaccat attcaacagt gctgtttcta
    62281 ctaattggca gtgcgctaaa ggcccttcca cttggattaa tggttcattt gcaaaaacta
    62341 gttctccttc acgagcagaa cgaactgttg ctttaaattc aaaattttgt aaatactcca
    62401 aaaaaccttc aggatagact tctaatccac gcaagtaagc aatatcggaa tcattgaacg
    62461 tcagattctc taaataattg actaaccgtt ccaatcctgc aaaaaccgcg tatccgtggt
    62521 taaaaggcat ttctcgaaag taacattcaa aaacagcatg taaatcagct cgacctaatt
    62581 cccagtatgt ctgcatcata ttgatttgat atagatccgt atgcagcgtc aaactgtcgt
    62641 ctgggtaagt attattcatc ttgtattact cctcttggca agttttcatt tcctacccat
    62701 tataacaaaa aaaattaata ggaaaagaaa tcttccattt tttctgaaaa agcacatgtt
    62761 ttacggatat ttcttgctaa aaatgaactc catctgctaa aactatcctt tcttattggt
    62821 atttaaccta aacgagaaag aatacttatt ttattcaatg tatccgagac acgaagaaat
    62881 tagcgttttc tatttttctt acttgataaa ataagtagat tttcctacta caatcgtagc
    62941 cgttaagata ccgatgattg aacaaatata accaaatgtc tctacaacat aatcaatggc
    63001 aaaagttttt gaagcaataa tacgtctttc cttttttgct tcttatcccc aaagaaacgg
    63061 atataactta ttatgtattg aatttttttg gaaaggcgaa ttatgacaag atataccttg
    63121 cgttgaaaaa actcgcggaa aaaatatcac acgtttttaa aaagatacaa agtaagaaag
    63181 cagctgtcaa tagaatggaa acaaaaatgg cgagacatca atcagtctcg ccttgttttt
    63241 tattgtatac attagatatg gagcaggtta ccataaagat gattattagt cgttattaaa
    63301 tagaatcctt cgtatttttt tgttctatca ctacaatatc tttatttgga cgtttgaatt
    63361 gtattccggc acgttctagc tcctgtttca ctcctacatg gactttgaca tcttctcgtg
    63421 tcatttttaa aacgtgatga atcgcatagt cgatttcttg ccttgtgatt tttttcttcg
    63481 tattgatcat cacgacttgc tttttatcat atgtgtctac caatagcagt tgtgttcgat
    63541 ctaacgaaaa taatttgtaa taattaatag ccgtattccc aaaaaagaat tccactactt
    63601 taggataaaa tgtcttaata tttaaattac tattcacagg tgtttcgatt agcttcatct
    63661 cattcctctt ttctatatag tcgatttaga tccaatctta agttatgtta ccatctttcc
    63721 tagcattaag gaatcggtta caattgaacc tttaaagaca aaaggattta ccttttatca
    63781 cttaatagta taacataatt tcgtgagaaa aaaatacaat tttttcttga ccatctcgtt
    63841 acgtaaagga ttatgcttac atttgtcagg aggaaaaata atggagtaca caataaagaa
    63901 aatgtcagag atatcaggag tcagtccgag aaccttgcgc ttttatgatg agattggact
    63961 gctaaaacca gctaggatca attcttcagg ttatcggatt tatggcaaaa aagaagtcga
    64021 tcgtctgcaa cacatcttat tttatcgaac aatggcattc aagttggatg atatccaaga
    64081 ggtcttagac aatccatctt ttgaccacca gaaagcttta atcaagcatc agcaaatgtt
    64141 gctggaaaaa cgggcacaaa tcgataccct cttgacaact gtccaacaga cacttgatat
    64201 gtacgaagga ggaagaaaaa tgagtgacaa agaaaaattt gaagggttta aacaacaaaa
    64261 gttgaaagaa aatgaagaat cctatggaca agagattcga caaaaatacg gaaaaaaaaa
    64321 ggttacagca tccaatgaaa aatggatgaa tatggataaa gaaacgtatg aagaaatgca
    64381 aactgttgaa aagcagatgt tatttgatct cactctttac ttaaaagaac cagaagatga
    64441 aagcttagca gaccgtatct tccaagctca taagaagtgg ttctcttaca gctggcctga
    64501 atatcagcca aaagcgcata aaggactagg aatgatgtac gaagccgatg aacggttcac
    64561 tgcatattat gacgagcgaa gtggtcatgg tgcagcaaaa gctttaaatg aaattatcca
    64621 aaaaaaggcg taatctttta catgatccaa caaaaaagta cacgtaaaat gacctaataa
    64681 caaaacagca gacacccaag ttagattttt atgctaactt ttggtgtctg ctccattctt
    64741 tcacaagttt tttcatccta ctttaaatat attcatcgtt gaataaacgt ataaggtatt
    64801 ttcactttat cctttttttc tgtaagaaac aattgaaatg ccatttctcc gcaagcttcc
    64861 agatggtggt cgatggttgg gaaaccaaga agctcgctga tcagcaaatt atcgcgtcca
    64921 atcaccactg gtgtcttatc ttgcagatag ctttgcaaga tgcctgctgc aaccatatcc
    64981 gaatttgtaa agacaccatc aactccaagc tctttaaaaa agaagcctgc ttgttttcct
    65041 ttctctgcat ctatacaatc ccaaaaaaca agtgattcat caaaagatgg aaaaagttga
    65101 tgacatagct gcaaagtgat ttttgagtta taacttagcc tgccacttcg ccccaacgtg
    65161 atgcccaatt gctttatacc ttgctgcttc aaataagtaa gaccttctgt aattgattgt
    65221 tctcgatcaa taaagacaca gcttgcctgt tttcccttga tttcttcaca aaaaactaga
    65281 ggtccatatt tttgatatgc caataaatca tctagtgtat tggcacgaga cgtaatgatc
    65341 aatccatcga aagctttagc tgcaaattct tcaagatacc ttcgctcttt ttctttatga
    65401 tagcccgtcg gtaaaagtgt cactttgtaa tcataatcaa acgctgcttc aatgatccca
    65461 ctgatcaact gatcaaaata cggatgattg gtataaggca gaatcactcc aatgcttttc
    65521 gtttttccat aacttaactg tctggcattt gcattaggga tataatcgac ttctttcatg
    65581 accgcaagta tttctttcct tttttcctca tctacatatg gatgtccatt gattacacgt
    65641 gaaatagtag aaactgaata acctgtgagc tttgcgatat ctcgaatgtt tgccactgct
    65701 gcttcgccac ctatacaaaa agattttctt gtaaatagtc taccacagct ggaccgcatt
    65761 caaaaaactg atacattttt ccttcatgcg aaaaactgat ccgctgcccg ccccaatata
    65821 tatcttttgt caaattttcg atttcattca ttggtatttc ttttactata ttcctattca
    65881 acccttgaaa actgtacaac gttaatacgg atcccttgaa ctcgacaaac gcataaaaat
    65941 aattgttcgt tgtgccatct gttatctcta cataagtatt cattgcaagc cctccttttg
    66001 atactttgag tatagtgtat gaaacgcgtc tcatagcaag gagtttgttt tgccaaagaa
    66061 aagttttatt cctctttcat tattaccaaa gtctcttatt ttaaattgaa tacattataa
    66121 tgatactgta aatatatctt tattattagt gaat
//
LOCUS       DAFELK010000008        65303 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFELK010000008
VERSION     DAFELK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.008"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            233..619
                     /locus_tag="LP433_000702"
     CDS             233..619
                     /locus_tag="LP433_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2004891.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            713..904
                     /locus_tag="LP433_000703"
     CDS             713..904
                     /locus_tag="LP433_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004892.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            1418..1750
                     /locus_tag="LP433_000704"
     CDS             1418..1750
                     /locus_tag="LP433_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2004893.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            2046..2201
                     /locus_tag="LP433_000705"
     CDS             2046..2201
                     /locus_tag="LP433_000705"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBL2004894.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            2477..3817
                     /locus_tag="LP433_000706"
                     /pseudo
     CDS             2477..3817
                     /locus_tag="LP433_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4058..5674)
                     /locus_tag="LP433_000707"
     CDS             complement(4058..5674)
                     /locus_tag="LP433_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL2004895.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEEIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            5792..6010
                     /locus_tag="LP433_000708"
     CDS             5792..6010
                     /locus_tag="LP433_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004896.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            6205..6666
                     /locus_tag="LP433_000709"
     CDS             6205..6666
                     /locus_tag="LP433_000709"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2004897.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(6859..7098)
                     /locus_tag="LP433_000710"
     CDS             complement(6859..7098)
                     /locus_tag="LP433_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004898.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(7122..8645)
                     /locus_tag="LP433_000711"
     CDS             complement(7122..8645)
                     /locus_tag="LP433_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL2004899.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(8663..8785)
                     /locus_tag="LP433_000712"
     CDS             complement(8663..8785)
                     /locus_tag="LP433_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL2004900.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(8815..9798)
                     /locus_tag="LP433_000713"
     CDS             complement(8815..9798)
                     /locus_tag="LP433_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL2004901.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(9822..9971)
                     /gene="rpmG"
                     /locus_tag="LP433_000714"
     CDS             complement(9822..9971)
                     /gene="rpmG"
                     /locus_tag="LP433_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL2004902.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(9992..10369)
                     /locus_tag="LP433_000715"
     CDS             complement(9992..10369)
                     /locus_tag="LP433_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004903.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(10401..10580)
                     /gene="rpmF"
                     /locus_tag="LP433_000716"
     CDS             complement(10401..10580)
                     /gene="rpmF"
                     /locus_tag="LP433_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL2004904.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(10595..10864)
                     /gene="rpsN"
                     /locus_tag="LP433_000717"
     CDS             complement(10595..10864)
                     /gene="rpsN"
                     /locus_tag="LP433_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL2004905.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(11387..13153)
                     /locus_tag="LP433_000718"
     CDS             complement(11387..13153)
                     /locus_tag="LP433_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004906.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(13113..14867)
                     /locus_tag="LP433_000719"
     CDS             complement(13113..14867)
                     /locus_tag="LP433_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2004907.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(14977..15546)
                     /locus_tag="LP433_000720"
     CDS             complement(14977..15546)
                     /locus_tag="LP433_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBL2004908.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(15564..16979)
                     /locus_tag="LP433_000721"
     CDS             complement(15564..16979)
                     /locus_tag="LP433_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2004909.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(16990..17658)
                     /locus_tag="LP433_000722"
     CDS             complement(16990..17658)
                     /locus_tag="LP433_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL2004910.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(17788..18372)
                     /locus_tag="LP433_000723"
     CDS             complement(17788..18372)
                     /locus_tag="LP433_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2004911.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(18703..18936)
                     /locus_tag="LP433_000724"
     CDS             complement(18703..18936)
                     /locus_tag="LP433_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBL2004912.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(18951..19901)
                     /locus_tag="LP433_000725"
     CDS             complement(18951..19901)
                     /locus_tag="LP433_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL2004913.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(19898..20740)
                     /locus_tag="LP433_000726"
     CDS             complement(19898..20740)
                     /locus_tag="LP433_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL2004914.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(20742..21461)
                     /locus_tag="LP433_000727"
     CDS             complement(20742..21461)
                     /locus_tag="LP433_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL2004915.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            22153..22311
                     /locus_tag="LP433_000728"
     CDS             22153..22311
                     /locus_tag="LP433_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2004916.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            22383..23609
                     /locus_tag="LP433_000729"
     CDS             22383..23609
                     /locus_tag="LP433_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2004917.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(23697..24089)
                     /gene="rpsI"
                     /locus_tag="LP433_000730"
     CDS             complement(23697..24089)
                     /gene="rpsI"
                     /locus_tag="LP433_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL2004918.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(24105..24548)
                     /gene="rplM"
                     /locus_tag="LP433_000731"
     CDS             complement(24105..24548)
                     /gene="rplM"
                     /locus_tag="LP433_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBL2004919.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(25067..25534)
                     /locus_tag="LP433_000732"
     CDS             complement(25067..25534)
                     /locus_tag="LP433_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBL2004920.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(25654..27192)
                     /locus_tag="LP433_000733"
     CDS             complement(25654..27192)
                     /locus_tag="LP433_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBL2004921.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            27272..27958
                     /locus_tag="LP433_000734"
     CDS             27272..27958
                     /locus_tag="LP433_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBL2004922.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(28159..28686)
                     /gene="msrA"
                     /locus_tag="LP433_000735"
     CDS             complement(28159..28686)
                     /gene="msrA"
                     /locus_tag="LP433_000735"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2004923.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(28770..29447)
                     /gene="pgmB"
                     /locus_tag="LP433_000736"
     CDS             complement(28770..29447)
                     /gene="pgmB"
                     /locus_tag="LP433_000736"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL2004924.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(29444..30574)
                     /locus_tag="LP433_000737"
     CDS             complement(29444..30574)
                     /locus_tag="LP433_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL2004925.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(30574..32757)
                     /locus_tag="LP433_000738"
     CDS             complement(30574..32757)
                     /locus_tag="LP433_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL2004926.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKGIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(32754..33779)
                     /locus_tag="LP433_000739"
     CDS             complement(32754..33779)
                     /locus_tag="LP433_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2004927.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(33824..34651)
                     /locus_tag="LP433_000740"
     CDS             complement(33824..34651)
                     /locus_tag="LP433_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL2004928.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(34648..35715)
                     /locus_tag="LP433_000741"
     CDS             complement(34648..35715)
                     /locus_tag="LP433_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBL2004929.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(35741..36577)
                     /locus_tag="LP433_000742"
     CDS             complement(35741..36577)
                     /locus_tag="LP433_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2004930.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(36574..37443)
                     /locus_tag="LP433_000743"
     CDS             complement(36574..37443)
                     /locus_tag="LP433_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2004931.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(37513..38796)
                     /locus_tag="LP433_000744"
     CDS             complement(37513..38796)
                     /locus_tag="LP433_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBL2004932.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(38810..40495)
                     /locus_tag="LP433_000745"
     CDS             complement(38810..40495)
                     /locus_tag="LP433_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBL2004933.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            40770..41795
                     /locus_tag="LP433_000746"
     CDS             40770..41795
                     /locus_tag="LP433_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2004934.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(42390..46064)
                     /gene="rpoC"
                     /locus_tag="LP433_000747"
     CDS             complement(42390..46064)
                     /gene="rpoC"
                     /locus_tag="LP433_000747"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBL2004935.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(46122..49739)
                     /gene="rpoB"
                     /locus_tag="LP433_000748"
     CDS             complement(46122..49739)
                     /gene="rpoB"
                     /locus_tag="LP433_000748"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL2004936.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            50467..51435
                     /locus_tag="LP433_000749"
     CDS             50467..51435
                     /locus_tag="LP433_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2004937.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            51453..52358
                     /locus_tag="LP433_000750"
     CDS             51453..52358
                     /locus_tag="LP433_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2004938.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            52355..53161
                     /locus_tag="LP433_000751"
     CDS             52355..53161
                     /locus_tag="LP433_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2004939.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            53297..54286
                     /locus_tag="LP433_000752"
     CDS             53297..54286
                     /locus_tag="LP433_000752"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBL2004940.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(54603..55127)
                     /locus_tag="LP433_000753"
     CDS             complement(54603..55127)
                     /locus_tag="LP433_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBL2004941.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            55414..57225
                     /gene="scm"
                     /locus_tag="LP433_000754"
     CDS             55414..57225
                     /gene="scm"
                     /locus_tag="LP433_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBL2004942.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(57380..58366)
                     /locus_tag="LP433_000755"
     CDS             complement(57380..58366)
                     /locus_tag="LP433_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL2004943.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(58389..58955)
                     /locus_tag="LP433_000756"
     CDS             complement(58389..58955)
                     /locus_tag="LP433_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBL2004944.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(58969..59385)
                     /locus_tag="LP433_000757"
     CDS             complement(58969..59385)
                     /locus_tag="LP433_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL2004945.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(59842..61776)
                     /locus_tag="LP433_000758"
     CDS             complement(59842..61776)
                     /locus_tag="LP433_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2004946.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            62057..63013
                     /locus_tag="LP433_000759"
     CDS             62057..63013
                     /locus_tag="LP433_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBL2004947.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            63103..64206
                     /locus_tag="LP433_000760"
     CDS             63103..64206
                     /locus_tag="LP433_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBL2004948.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            64219..65172
                     /gene="menA"
                     /locus_tag="LP433_000761"
     CDS             64219..65172
                     /gene="menA"
                     /locus_tag="LP433_000761"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBL2004949.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
BASE COUNT        19805 a        13247 c        11325 g        20926 t
ORIGIN      
        1 ttagccataa ggacatgttt gatatttaag aagatatatg aattttcttt tctaagtata
       61 aagataacta tccattatca actaaaaaaa catttttgaa aataaacatc agcagtccta
      121 tcaatgcatg tgagcttata gaagttattc gcagcgcagc ataattgcat tagcttcttt
      181 tcgtgttttt tgcctctttt ccctttaaat cttaatggag gaggtgtgca atatgtcaga
      241 taacgacgaa cgcgtaaatg cccagttgat tcgattcttt gaaaaggtca ttttgaacac
      301 cgctaatact tattataaaa aacaagaaga aattcaaaaa catgaacaac ttgatcaact
      361 cccaccatat ttgtttacta aagatactat aaaatttaaa caaccgatta atgttttaaa
      421 tgtgactctc cttgttgaag atataaaatt agcaaaaatc cttcctttgt tgaaagaacc
      481 tgaacaaatt tttcttatcg aaaaatttat ctttgataaa actgataaag aaattggaaa
      541 ggttctgggg attacaagac agggtgcgac aaatttaaaa catcgacttt acaaaaaaat
      601 tcaaaaaatg ctggtttaat atctgcataa taactaattt tgtatgcttc tttgctcgtt
      661 ctcctccttc ccaaagaaat agattataag tccatgggaa gaaggtagat ttatgaattc
      721 tttaaaagaa gatttcattt tagcaaaggc tggaaatgaa gaagctgttg aggcaattct
      781 caaaagattt agctctttga ttcataagca atcctggaga actggaaaat atgatcaaga
      841 ttgttatcaa gaatgtatgc ttgcaatata tctagctatc tcgaaattcg aaattaaaga
      901 ataactcaac taagggagtc tgtgacataa gtaaaaagat agtttcaaat ttcgaacaat
      961 aaatttgaaa ctatcttctt tataattata aagtatcgat tttacagcgt tctataatga
     1021 ttcatagaat ctaaaacgaa tgattttaat tatcaacgtt ttttaattcg tttttagctt
     1081 aaaaataact tttgtcacag tctcactcct aaaattactt tatttacgta tgaagtgggc
     1141 aggaggtcga atccagaact gggctatggt acttcaacga ggacttctcc tctagaattg
     1201 aaaagcatgc gatttacctt ccgtaacgac ggtagattta ttcaactatg tgtccaatca
     1261 aaatttgtct gatttcaaaa atagtcaaga gaattttggt tgttaaaaac tcttatctat
     1321 caacttccac agtttagttg acaaaccctg atactaagtt gggctatgat acacttttct
     1381 tgactatcag ttacgttacc ggaaggaatg aactctattg agaaaaacat atgatcgtaa
     1441 atttaaacta aagatttcac aggatatcct tgagaaaaaa gtaactacca agaaaattgc
     1501 tgaagaatac aatatctctc gtccaacaat ttcccgatgg gtttcagaat atcgtcgata
     1561 cgggaaaaat gcttttgctg gacaaggaaa aagattacct gataaagcag atttctacat
     1621 tcttgaacag gaaaataaac gactaaaaga ggaagacgag tgttctacga acacaaagat
     1681 cgatacggat ctccagggat cactcaaaaa ctttacgatg aaggaatcga aatcaataaa
     1741 cgtgttgtag ctgttcttat gcgtgaaatg aatttatgca caagaggatt tcatcgacgc
     1801 aaatcttctc atggtagaga aaaaacaatc aaagaaatgg taaaaaaatg ttgaatcgat
     1861 aatttgaaca gaaccaaatt gatgctgttt gggtgatgga tattacttac attccatgta
     1921 atgacggtcg cctctatttg tccacctata ttgacttagc aactcgtatt ctacgttact
     1981 atatggtaga ttcacacatg aaaaaagaga ttgtcgtccg tccattacaa atttattaag
     2041 gagaattgcc tacggtaatt cattccgata gaggtagcca gcatcggtct tttatttatc
     2101 aagagctgtt gaacgaccac cacatcacac attcagtgag ccaaactggg actcctgttg
     2161 acaatgcagt aattgaagcg tttcatcgat caatcaaatg agaattaatc gactccaaca
     2221 aatataaaag taaaatagag atgaaggtgt taatccaaga ttatttagaa gactactacc
     2281 caaacaaaag aatccataca aaatttatga tgactccttg acaatttgaa gcgaagaaaa
     2341 taagggatct ataatatcta gtgttggtga cgccttctgt tgccaatact ttttcttttt
     2401 tctaataaac gcaaacagac accttaaaat cctttagaat aaagtcgacg aaaaccattc
     2461 aaaggagtgt ttcaagatgt cctattcaga gtttaccaaa gagttactag atattctaga
     2521 cctaaatctt atctttcatg aagatgcctt tcgcaaagag cgaatcaatg acgaaacatg
     2581 ttttgttttt gatggcacat tgacctatca accggaggaa tgctttcatc gccactatca
     2641 aaatgaacaa acgatcatta aatagggctg gaaaaaagta tccatcttat tgaatgatgt
     2701 cagtaactac aagaccattc tgcggattaa caaacagcgc ttcaaatgta aacactgtgg
     2761 aaagactttt ttagcagaag attcagttag tgatcgtcgc tgctccattg ctcgcagagt
     2821 caaacaagcc attcttgagc tattaagcga acctctttct atgtctttga tcgcacgtat
     2881 gaagcacatt tctccgacca ctgtcattcg aatacttcgc agccttcggc ctaaaaccat
     2941 ttctttgagc cagctgttac cagaagtggt gtgtttcgat gaattcaaat cagtgaaaaa
     3001 tgtctcggga gccatgagct ttgtcatgat ggacggcaag acccatcaac tgattgatat
     3061 tgtggaaaat cggcaactca atcctttacg cgactatttc ttgcgctacc ctataaaagt
     3121 ccgtgaacaa gtgcgtctag tggtttcaga tttctataca ccctatcgca cattggtgaa
     3181 agagtgtttt ccgaatgccc gaatcgtcgc cgatcgcttt catattagcc aacacattgg
     3241 tcgggctttt accaaccacc gaattcaagt aatgaagacc tttaaaaaag gggatcgtcg
     3301 gtcgaagcac ttaaagaaat actggaaact acttcaaaag aatgcgtggg aattgaaagg
     3361 tcagcatcgc tactggcgtc cgtcatttcg agatcatctg acagaagcag agatagtcga
     3421 tcggctatta tcttatgatg attccttaaa gcgaggctac gaagtctacc aggattttct
     3481 ttccgttatc agaagacaag atgttcctga attcgtcgcg ctcctaaaag aagactacaa
     3541 ggagttgcca gagcactacc aaccagtgtt cacgaccttc aagaaatacc aaacagaaat
     3601 caaacgagcg ttgcgcgttc cctattccaa cggccctata gaatgtttga ataaccatat
     3661 caaagtacta aaacgaattg cctatggcta tagaaacttt caaaactacc gagaacgaat
     3721 ctttttatat cgaggaaaat attttaagaa aactaagaat actacccaac tgactaaagc
     3781 cagaacaaca acacggctag acaagatagc tgtctagccg tgtgagtatc tcgattattc
     3841 tattgaattt cttcaccaac actcattgac gaagagccaa aataagtaat ctaaccgact
     3901 gttaactaaa ccattgcagg tcccgttaaa gatacttgtg cctgttgtca ccgcttcttt
     3961 ttcttgtcca caagcgctta acacacttaa taaagcccct gctattatta ataataatat
     4021 ctttttctta ttaaaaacct cctcatctat ttccagatta gtaaatgtag taatctgtgc
     4081 tttctttttt ctcaatacta ataactaact tatggggtaa acaaatactc gtttgaccgg
     4141 gttttgagat ccatccagtt ctaaccgcga tttgatcagg actattatct tctttaactc
     4201 gaattcttcc atctttaatc tcaacaatat tatattgtcc cttcgcagga tgataattca
     4261 cgagtttatg attgatctta tccaaatcga agcgatccat ttccttgcca tcaattcgaa
     4321 cgatggcata tttgatagca tcttcagttg tttcattctc cttttctata gagaatacaa
     4381 ataagggaat aaaagaggta ataatcaaaa tgccaataat tatgacatcg cctatcttga
     4441 caccagcttt tcttaaaaat ttcattaacg atatctggct aaacatatta gactttttcc
     4501 atggaaatgg tgaaattttt cggaaattat ctgcattaag agaatcagtt aaacaaccct
     4561 caagttgttc cttaatacat tgttgatcca tcttcatacc aataaaaact agtttattaa
     4621 tgcgttcacc aaacaacgga tgccaggctt ccttcaattc gggatttttt tgtataatca
     4681 tttgacactc aattttaggt aaactagcta cccaataatt taatgattca atacttttat
     4741 agctacccga tgtttcaaag atcgtcgaaa aatcactatg ttgggcaaac caaagaaacc
     4801 cttttgctct tgtaatattg ccaggaaaat ttttatccgt aagatgggca aatttttgtg
     4861 cgtcaaggag taaccgattt cgatagataa aacttgagat accatattct tctgtttcag
     4921 gaatatgatt ttgatagcca agctctaact ctttgaacca gcccactgaa taggaagtct
     4981 catctatatt aaaaagattt gtatttagaa ttttcgataa gtctacttca cctttaattg
     5041 tcctaattat tttggcattg gactgtaact tagcaattag accgttaatt ttgtaaatcg
     5101 tcttggttga cactaagtca ctattattta aaagtaatat gttacaacac tcgaattgat
     5161 caattaacaa gccacgaata tcctgttctt cttcaactac attaccttca gcttttcttt
     5221 cctgaatctc ttcacccgtt tcgaaattat cccaaaaacg ttttacatcc actactataa
     5281 taatggcacc aatctctaat cgttgggtca aatcaatgtc taaagggttt ttagctaata
     5341 taattgcttg aataattgga attggtttgc tgattcctga agcttcaata acaatttgat
     5401 tcaagtcaga aaattgcact aattgatcta gttcaacaat caaatcttcg cgtaatgtac
     5461 aacaaatgca tccattcggc atcgaaacaa gtttttctcc agttctttta aaacctttct
     5521 tgtcgactaa taccccatca acatttactt cccctatgtc atttacaatg acagcaattt
     5581 cctttccgtg atcaccgtac agaatatgat ttagaagtat cgtttttcct gaaccaagat
     5641 agccagttaa gattgtaata ggtatttttt tcatagggaa cctctttcta taccttgaat
     5701 ttacacttta agtgcaacac ataaaaatga gtcataatcg atatccaact agtataagtt
     5761 tgtcgagaac actcctagaa ggaaaataat tatgagccag tatcgtcatc ttactatact
     5821 cgaacgagaa agaatctttc tgcttcacga agaaggattt tctattagta taattggcaa
     5881 cgacattcag catagcccgt ttactatttt acatgaactg agaagaaaca agaaaaaaac
     5941 tattcacctt ccaaagcgga aaaaaattat gcttatcgaa gaaaaaaatg cggacgttat
     6001 cacattctaa atgatccgtg agtttggtca attgttcgtc atttatttgt cgattttcag
     6061 tggtcgccag aggaaatctc gaatcgtttg aagcatgaac atatggactt ttcaattagt
     6121 tttatcacga tctaacgtgc aatttgcaat gatcttttcg atacagaacc cctctcacac
     6181 ggcaataaag gcctgatccg ttcattgcac catcgaggaa aaacaagaca tacaaaaaat
     6241 catgtcgagt ctcgtggaaa gatttgcctt actcattcga tccatggccg tccaaaatcc
     6301 gcagatgata gaagtgattt tggtcattgg aaagccgata ttgtagctgg caaaactggt
     6361 ggtacttgtt tagtgacttt gacagacaga aaatcatgct tccttttagc aggaaagaag
     6421 gtccccagaa agaaagccgc ttatgtgagc gagaaaatga ttgaactttt aagcagtatt
     6481 ccaaatgagg cggtcaaaac gatcactcca gatagaggaa aagaattctc caatcatttc
     6541 gcagttacag aagcattgaa taatatgccc ttttattttc cagatcctca tgcccttggc
     6601 aacaatgaac aaattaaaat acgaatagac tcattcgaga atacttgcca aaatcgaaag
     6661 agatagctac ggtagataac tcaacgataa atcagatgat tgaaaaactg aataacagac
     6721 ctagaaagtg tttagattgg agaacacctt atgaagtctt ctttgataaa gtgttgcgct
     6781 tgatttgaca attcaagaca taataaaaag cagatcaaat ccaaataagg gaaaaatgat
     6841 ctactctggt attatcaatt aattggccaa gctattatgc cgttttgcta aacgtctact
     6901 tcttccagta ttgaccttga taaaacaaca atcaggatcc cgttttaata ctctatgaac
     6961 tgtgtcaata ctaacatgta aagttgcagc aatatcagct aatgtactcc catttaatct
     7021 catttgcttt gcaaatcgat aacgccgata agcatcaata ttcttggaat ccatagacaa
     7081 taatactttt cttaccatgt atttcctcca aaaattgaat tttaatgagc catcatttct
     7141 tgagcaattt catgtttaga caatgaagct ggatagaaag taggccaatt atgcaattca
     7201 ttatagagtt tttcttgact ttctccacca aagaaaatat ggaaatgctc tgccttactt
     7261 ggtgcaattc catgatcact aaattgaata tatttaaaac gaccagcacc tgcatcatca
     7321 gtttcaaaat taaaacgaac accacggttt cctttttcat aattcaaaat tttgtatcca
     7381 acatatttgt atgtgtattg atgatgttca ccgttgacta caaaatcaat ggtgttgtct
     7441 ttaatgttga tagtatcaat atctgtctta tagccagtag tataataatc tttgtactcg
     7501 gcagctgtca tgtctttatt gatttttgct ttgtaatcga aaacttcatc caaaattcca
     7561 tcttttaaca acggataaac agattgccat tcgcctgtat aatcactcaa ttcgcgatcc
     7621 ttcacatcgg catctttaaa gtacccatta gcaactgtct tttcatcctt cgcttctttt
     7681 tctggaacta cctcttcacc agcaaccata gttgtttttt ctaacgcttt tagattgtct
     7741 tccattactg aaacataatc ttcaccatta tccatttgtt cttttgtaag actttcaaga
     7801 ggattcagta cttccaattt tatcccagct tcgttggcca aagtttttgc aattttatca
     7861 ttagcattct tttcaaagta aatataattg atcttatttt ttttaacata ctcttttaat
     7921 tcagctaatc gaccagaaga tggctcttct tcaggactta gtccagcaat aggaacttgt
     7981 ttcaatccat aatccaaagc taaatatcca aaggctgcgt gttgcgtcac aaaacttttt
     8041 tgtttcgctt ctttaagact agtggtatag tcagcatcca accgtttcag tttagtcaaa
     8101 tacttttcag catttgtctc aaatactttt gcttttttcg gatacaattt aactaactga
     8161 tccttgatat ttgaaacttc cttaattgcc attttgggtg aaacccacgt atgaggatct
     8221 agttcatgat ggtgatcttc ttctccgtga tcatgatctt cttcttcact acctggcaat
     8281 aaaatcatgt cttttgttcc ttctactaca ttaggcccag ctttcttcca actttcttta
     8341 gcttttggta cccatgattc catgttttcg ttatgatata caaaaacatc agcatcatga
     8401 gcttttgcca tatccttagc tgagggctca tagtcatgag gttctgatcc cgctggaacc
     8461 attaaatcca cgttcgcttc atcgccgacg atgtttttgg tgaaatcata cattggatag
     8521 aatgttgtta caatttctaa ttttccatct ttatcattcg atacttttgc atcattagtg
     8581 ctggagcaag ctcccaataa tcctagagct gctatcccaa taagtcctac actgattttc
     8641 ttcattcttt ttccttcctt aattatgcta atttcttcat tttatttcgt ttatgttctt
     8701 tgataatttt taatgccctt tttctagttt taatattcgg gcttttaagt cgtcgatatg
     8761 cactagatat atccgttttc tccattagaa attaccccca atcactactt atcattattt
     8821 gctttccgcc agtaatttat caaaactctg tttgatcctt tcttcatcca acatttttcc
     8881 gattagaata atagtggttt ggtctttttg tcgagtggtg tattgaaaat taacctgttc
     8941 gtttacctct tgcatggcaa ctataaaatc ctgctcttgt aaagcaatca atcctttaaa
     9001 acgatacagg ctcccttggt tggttaaaat cagccagtca atccattgga gtaaaaaatc
     9061 tttttttatg tcttgatctg aagttaagag aattgattta aactcatgta cttgatggtg
     9121 ttgatgatag tatttgccat tatagtgatt ttctgatgaa tcactttcaa aaactaaggg
     9181 atgattaaat tttttcaaat tataaaaatc ctttttttga atcgtttcac tatgtgtgaa
     9241 cattcgaata tcggataaag ggttaatact tttgatttct ctctgtaatt tttttagtgc
     9301 agataaattc aagttttgtt ttctagacac aaaaatgcga tctgccatga caagttgctt
     9361 aagggcttgt ggttctcttt caataagttc aaaactgtca ctatcaataa cagtcaataa
     9421 actatcgata tatactcttc ctcttagttg aggcgctgtt aaaagtgttt gaatgattgg
     9481 ttggggatct gctatacctg tagtttcaat gatgatttgt gaaattggtt gttgatgttc
     9541 ttctattgtt tccagtaaag aaatcaatat tgctaataaa tcactgcgaa gactgcaaca
     9601 catacatcca ttatttagtt gtaacacccg ttcctcgcta tgaactaata atttgtgatc
     9661 aatcccaact tcaccaaact cattttcaat tataataatt tcttccctgg ggtagggtga
     9721 gacttgcaag gcttgattga ttagcgttgt ttttccagcc cctaaaaacc cagaaacgat
     9781 tgtaactggt atgcccattt tgtcaccttt ttaccactta gctatttcac ttctttaaaa
     9841 attgcccgtc tgcgcaattt tggcgaatac ttttttaatt ctaaccgttc agggttattc
     9901 cgtttatttt tgctggtgag atacagacgt tctccagttt cgacacattc caaaataata
     9961 ttttgacgca taaatcttcc tccttcaata cttatcgatc ttcaagatat gcttgaattt
    10021 gttgtgcatc ttcaaaagtt aactcgccag attccaattg tgaaactaaa ttttctttca
    10081 tatcaacagg tatctcccaa taaccatcga tacattgaaa taactcctcg tcatactctt
    10141 caaaaattgg atagattctt aaaaaatcat caaatgataa gccttggtcc tcatagtaat
    10201 ctttgactaa tccattttca attgcctgtt gggtcggtaa acccgtttca gtaataattc
    10261 ctctctctac catcgaacga taaaaagtgc atttatctag cgattgctgg gtcgtttcaa
    10321 gataatactt taatccttct tcaactaaag gtgggtaaat aatttccatt ttgattccct
    10381 cctaaaagtt atatattaaa ctattttgaa gctcctttaa ttactttctt tccattatag
    10441 taccctttta aagatacatg atggctacgt ctataatcac cattcgcttc gtcaaatgaa
    10501 atttctggtt ttactacagt ttgatgagtt cttcttaacc gtttcttcgc cttagatgtt
    10561 tttcttgctg gtactgccat gatatttcct ccttttacca acttgctttt tttactccag
    10621 gaatcaaccc ttgatgggca agttctctaa acttaatacg ggacataccg aactttcgca
    10681 tataccctct tggacgacca tccgtctgat cacgaagcct cagacgattc ggatttgaat
    10741 ctcttggcaa tttagcgaga gcggtgcgat ctcctgcggc ttttaattcc tgacgtttat
    10801 ctgcatactt ttcaatcatc gccatttgtt tctttgcttt agcaattttc gacttttttg
    10861 ccatatacct ttatactcct tttattttga tttagacacc tcaaatcgta atcgttacgt
    10921 tttgacactg atactttacc aacaagagtt gctcttgtca acaataaata acatgaaata
    10981 aaactcatat gaatagataa ctatttgaaa acgaatttat cggtacatag agataatcaa
    11041 atcatttaaa agaatatgca gtttaggctc tgaaaaataa gaattcactt ttattagtcc
    11101 aatcaaacac aaataccgtt ttaagtagct tttcctctac ttaaaacggc aatatgaaag
    11161 aaactataac tttttattca atcttttatg tttaactggt ttatcgccaa ttttttaaaa
    11221 ctttgattat tccttatatt ataagaatag acattaagtg aactaattca atcatactga
    11281 ttctttcgtg tattcaaaat tagatgctgt ttaataaaat tattcttttt gaaaaagaat
    11341 tataactata tcccaaaaat tgtaggttaa tttaaagcct atttcatcat cgtgattgag
    11401 cttctttttc atagacgaat ttctcagata gtttagtttt ctttatgaga tttttgtata
    11461 tttctgacct tcgatacaac tcattatgag taccttgatc aactagtttt ccttgatcca
    11521 tcactacaat tttatttacc ttttcaatag acttcaagcg atgcgatata attagtactg
    11581 tcttatcttg tattaaacga tttaaacttt cctgaatacg tttttcattt tccgcatcta
    11641 aactggcagt aatttcatct aaaattaaaa ttggcgcatt tttcaaaaaa gcccgtgcta
    11701 tggataggcg ttgtcgctct cctccagaaa gtgaacttcc gttttctccg accaatgtat
    11761 gataaccgtc aggtagtttt tcaataaagt cttcgcagtt agctaaacga gctgcttttt
    11821 tcacttcctc atctgacgct tgactatttc caatacgtat attttccaaa atacttgtat
    11881 taaacaaagt tacctcttga aaaacaatag cgattttgct aaacaaagaa gctggagata
    11941 cacgtttaat atcataccca tcaattaaaa tacagccttc atcataatca tacagtctag
    12001 acactaattt caagatacta gttttcccgg aaccactagc acctactaac gcagtcactt
    12061 ctccttgttt agccgtaaaa gagatatgat ctaaaattgg ggtattgtta tcatatgaga
    12121 aagagacatc tcgcaactca atgtcaaaag atttcagagg actatctgat ccctcttgga
    12181 tactggtttc cttcatagct ctaattcgct gtattttagg agctaaataa aatatttcaa
    12241 gcactgcttc tttcatagaa tcgaaggaat cctttatttt tattgcggct agtaagtaac
    12301 caacgacgta gagtatagtc acttcacccg ttaacagtaa gtgaacacct actagaatga
    12361 ctactgctaa actaacatat gagaaaatag aggataaggc catgactgaa aaagtactta
    12421 attctacctt taaatgaatc ctttcactct cttccatttt tttgaaaagt ctgtcttgaa
    12481 cttttttaga tagattaaag ctattaatct cttgctgcaa ttctatagtt tcttgaaatt
    12541 cttccgagtt ttctctcaaa gtatcgtaat atttagtatt ggctttcgtt tgggatttct
    12601 ttgataacaa gattaagaca aaactaaata acgttggcaa aataacagct aatcccattt
    12661 tgacattacc aaccaaaagc atcactgaaa taaaagggaa aaacagagcc ataccgccgg
    12721 ctttaggtat tgcatgactc atcgcatgct caataccttc aacgtcagac atgatagttt
    12781 gagataaatc tgataaatta tgttttgaaa aataggataa tggtaaattt gacaaatcgt
    12841 ctgcaatttg cactcttaaa tgcgcacttt ctttataagt actattatat aagttttcat
    12901 actccctatc taacaaccaa tacatgaaaa gcaaagtaac aaacgatacg gcaaaataaa
    12961 gccaacgggg ctttgtattt tctaaaacta attcgtctat cagcatcatt ataatgaatg
    13021 ctggtaccat attaatgcag tatacaaaaa aactagaaat agaagcttta gttaaagctt
    13081 ctgcgccctg atcacttaaa gcaaatttgt ttttataaaa acttttcatt gtcaagcctc
    13141 caatcatttg cattctcata attagtgacc aattgtttat acacttgatg tttagccatt
    13201 aattcattat gatttccacg ttctactatt ttcccttctg acaagacaag aatttcatct
    13261 acagatttaa tgctggataa tcgatgagct atcataataa ctgttttttc ttttatcaga
    13321 tgttgaaaag ccttttgtag ttcatactca ttatctggat caatagatgc actggcttca
    13381 tccataataa caatctttgc atcttttaaa attgctctgg caatagctat acgttgtttt
    13441 tctcctcctg acagataaac tcctttacta ccaattaagg tatgctctct ttcgggaaat
    13501 ttttctaaaa tcgattcgca accggctaat cttagcgcgt caaatacttt acttgctggc
    13561 gcttgaggat ttgctataga aacgttatcg taaatactct gattgaatag tttcgtatct
    13621 tgaaagacaa aagcaattgt gttaataatt gtgtcttttg aatagtgatt taaaggctta
    13681 ccaccaattt taatctgtcc cttatccaca ttgtagaaac ctgaaattag tttagctatc
    13741 gtactctttc cgcttcctga ttttcctact aatgcataaa ttcttttttg ttctaaaact
    13801 aagttgaaat tttctaaaac acactcttct ttgtatgaaa agctgacatt ttcaaatgca
    13861 atgtcacaat ttttaatctg tgtctcgttc ccatatttta gttggtcttg cttcatttct
    13921 aaataaaggg agtctagtgt ttcgactgca tatcttgctt caaacaagtg catacttaca
    13981 tacattattc tcatgaaaga aacaaaaata attccactta aaaaaaacaa catcaacaag
    14041 tcaacagcta atatcttggg agtggtaaga gaagttataa aaaaggttat aggaactatc
    14101 aaaatgcaaa ctatgccaaa aaatagccat tgaaaaagaa caaaaggtgt tttcccactc
    14161 aaagaatact tatatgcaaa cttagcataa tcgttaattg ctttattcaa ggctttaaat
    14221 gatgttactt tagcaccaaa tatctttata acttgaattc cgcggatata ttctaccgtt
    14281 tcagagctta acacatctaa cgattcttga tatttttgaa taaaatttgt attctctgtc
    14341 attttcttta acaagaatac accaattact aacatggcga ttagaaccaa tccaatttta
    14401 aagttaatga aaaagcctaa ggcaactgat aaaacaggtg ttactatggc ttgagcacta
    14461 tctggaatca agtgagcaat tgccatatgt gttttagccg cgttgtcatc aattgtcttt
    14521 cgaatatatc ccgaagaatt taaatcaaaa aaacgaaaac ttgcttctgt taaaccgcta
    14581 attccctttt ttctcaaatt agtctctaag cgaaacccaa ggatatgaga aaataagcca
    14641 gaaaaaatat aaaataaagc tcctaaagtt aaccaagcaa cagtttgaac cgcataactc
    14701 ttagctaaat attcatctcc tacaataatt agagactgaa gaaatttgta aatactgtaa
    14761 tatccataga ctgttaatac gacagaaaaa tcagaaaata aagtggctaa ccatccgtag
    14821 tatttcattt tagggacata actaaataat tttttgtata ctttcatttt ttcctccccc
    14881 gcattcaatt tcttctctta ttcgtttaca actgttaatg ctttccgtaa tagcgtaaat
    14941 tagagatgta caaacagata aaaggtaaac tacgttctat tttttgtatt tttttaagac
    15001 ttttcttcca atcaatacac caatcataga taaacttgct acaactaaca ctgaaatgat
    15061 tccccatata cctaccgcat agtggatcat tgcatccatt gttgcagcag attgtccttt
    15121 atctatccaa tcttgacgaa aacgatctgt aaagaaccat ataggaatcc actgtccggc
    15181 agcactgcct aattgcatta gagcccaaga cgcaacttga ggaattgctc gatcatatcc
    15241 aaatacagat agaataatat cagctaagat cgccatacta atcgaactga taaaccaagg
    15301 taagtacgcc ccgcccatta acgtaaaaaa taacaataaa acaattgtgt aaatagtaaa
    15361 aattcctttt ctagggtagt tatagctaat ataaacaaat atgattccag ataataatcc
    15421 aaaaatcccg ggggatatgc tgtgaccaaa cgccccacca atactactaa ccattattga
    15481 aaaaaagtaa attactaggg aaataactgt agctaaacca ataaaaatat aatcttttgt
    15541 tttcatatat attctcctca attctatttc gttatgtcat taaaaatctg ttctatcaaa
    15601 gttgaatctt ctactctaag ttttatatct ttttttattc caccattttt taaataaata
    15661 attctattgc atgttttata aagaaattcc ggatcatgag tagctataac tactgcaccc
    15721 ttttctttta agtctttaat aaggtcagca atcctttcca tattaatata atccaaccca
    15781 cttgtaggtt catcaaatag aaataaatta gtttttgaca atgaagctat agaaaccaat
    15841 aatctttgtt tttctccacc ggataaatca aacggtaatt gatctttcat tttataaagt
    15901 tccatttttt ttaaaatttt ttcttgctga tctttactaa ctatttcatt ccccagggct
    15961 aactcgctcc tcactgattc tgtgaaaaat tggtaatcca tttcttgcat tactaaaaac
    16021 ggcgatgaca aatttttttt attttcgatt atctttcctt tggtagggcg aataatcttc
    16081 atgagtattc ttagtaaggt tgttttcccc acaccgtttt tccctaccaa accaataaca
    16141 tctccaactt tgacatcaaa atttatgtct tttagaatat tttcataagt aatttcttca
    16201 acttttaata catctgcact taccttttcg atatagggaa cttcaatcga actattaaaa
    16261 atgtcaaatt tccttaatgc gttattgttt tcagttttta acaactgaat agttgtagtt
    16321 tttacagttc tatttttaac aaatagaact tgatcaatta attctttcaa atagtaaaaa
    16381 cgatgttcag ctataacaat agtaaatcct ttatttttta aatcacaaag taagtcagca
    16441 agtttcttag tcgctttgaa gtccaaattt gaagacggtt catccaatat aattaattta
    16501 gagtttagcg ataaactaca tccaatagaa attttctgcc gttcaccact tgatagcgaa
    16561 aaaatgtttt tatctaatat atttgaaaga tctaataatt cagctaattc attgattctt
    16621 ttatccatat gctcttttgt aaatccaaag ttttccatcg aaaatactaa ctcactcgtt
    16681 gtatttgttg taaagaattg tcctctagga tcttgactta cgtagccaat attttttgat
    16741 atactttctt gtgttaagga ttgtagcgag ttattttcaa ataaaatttc cccaaccaat
    16801 tttccgtcat aaagtcttgg aataagtcca ttcattaact ttaatagtgt ggatttccca
    16861 ctcccagaag aaccagtaat caatgtaaga ctgccttttt ttattgaaaa attaaggtca
    16921 acaagcgctt gttccttaac atccttatat gaaaaagaaa cattgttaaa ttcaaacaat
    16981 tctttcacct caaatcaaaa tacttaagaa aaaaatagta acggaaaaca ggatgatata
    17041 gtctaataag ctcatgtttg ttttatagta agaacttctt ttcacaggag attctatccc
    17101 ctttgttatt gcattagcgg tcatttcttc agcaatcata gttgcacgta taagaacggg
    17161 aactaacaga aattccaaat attgcagagg ctgaaaaaaa gacaagcgaa tgtttctcat
    17221 ttttaaagat tctttaatca ttcttatttc agaacgataa gtcggaaaga atctgatcac
    17281 tactgtaata cttaacatta tttttttcgg taaatgtatt ttttctaaag aggataataa
    17341 ttcattgcta gtatagacac taaccaacaa ccatgagatc attacgaccg gcaacattcg
    17401 aaatacaata tataaggatg tcgcaaaaaa tatagtaaaa aactctatct tgatagcatc
    17461 aataattttc attactaaaa acagaactga ataaatcaag atgaaataaa tacatgtctt
    17521 tattttacga aacatcaata ctaaaactgt agcaataatg aaacacccca cttgaaatat
    17581 atttcccttt cctaaaaaaa taatgaccgg aaaaaaaata tttaaagtaa tcaaggttaa
    17641 cggattgatt tttgacactc tttcacctcc aaaaaataag atcgcactgt tatcttaagc
    17701 tgataaaaat gcaccgttat tcagataaca gtgcgatctt atcaaaaagc ataactgaga
    17761 acaattctca atgcaagctt tttttaatta actcagtaat tcaatccacc caggaacaga
    17821 aaattgatac aatcttctgg ttaatagcat agtcttttct tttgaatagc tatgcttcaa
    17881 tatatcatag aatgtagcgt agaatgagta aatgtagaag tggatttctt cttcattaaa
    17941 gactaaattt tgattgatca ttccgatagt ctttaactta tctagacaac agactgtctt
    18001 tttcgtcaca aatgatgtaa ttttttcaac aatatcttga tatttggttc cagctgattg
    18061 gaataaaatc aaatcgaata tacgtttatt ctcaaaaata taattaataa atggatctaa
    18121 ttcattgaag ttctctctcc aacttttctc tatatctata ttttctaagt ttaagaggta
    18181 tttggtaaac tcttcattat acatattaat aagcgcatta atatgcggct gaataatttc
    18241 ttcaaataac gcttccttag aagtaaaatg tttataaaaa gcacccgtag ttacgcctgc
    18301 ggtcaggcac agttgcctta tcttagtttg ctgaaatcct tctttttcaa aatggcttag
    18361 tccactttct attaactttt ggtgagttat aatataatct ctggtttcta tgggtacttc
    18421 ctcctaataa gatgaattaa ctttattatc ttacacagga cttgaagttt caatcgttaa
    18481 cgtttattac tgaactcatt ccttagagct aaactaatga gaaagagcag aataactgat
    18541 acaaaaagca atcctacaag aattaataga ctcatctaaa tcattcacct tttctaaaat
    18601 aatccgagaa agatttaaaa aaattatatc cagctattag gataagtcct atcataatca
    18661 ctccaatagc cattttctta tcctccctaa aaataaagtc ttttacttaa aacctttttt
    18721 gtaatcgtca ataaattttt tccctttatc agttaattga aatcctatat ctaaatagtc
    18781 ctcatatcta agtttagcca gcatctcact tacagatgct ggactaacac ttagaacttt
    18841 tgctaaatca ttatttttta atttcttttt tctttttgat aattcctgaa ttgctagtaa
    18901 ataaattagt atagtagtcg ttttaatttg taccatacct accctccaaa ttatttcgaa
    18961 aggccttcag caattttatc caggttccat ttcatcatcg catagtaact atcaccatct
    19021 tgtccttttt ctgcaattga atcagtaaaa atcgttgaat agataggaat attggtatct
    19081 tttgatactg ttttcattgg tctatcatcc acactgcttt ctacgaataa ggagggaact
    19141 tttgttgtgc gtaatttttc aactaagtgt tttatttgat ctggtgttcc ttcttcttca
    19201 gtgttgattt cccaaatgta agcagaaggc acattatacg ctttcgagaa atatttaaag
    19261 catccttcac ttgtaacaat cattttttta tcattcggaa ttgaagcaaa tttagattta
    19321 gcttctttgt ctagagaatc caatttttca atatacttat ctagattttc tttatagaat
    19381 tttttattat caggatcttt ttccgctaac tgtttttcaa tatttttagc gtaaataata
    19441 ccgttttcta aatttaacca agcatgagga tcttccttcc ctttctcact ctgaccctct
    19501 aagtaaataa catctatgcc atcacttgct gcaaaatagt ctttgttttc ctctttgttc
    19561 gcatttttaa ctaattttgt aaaccaagca tttcctccag tttccaagtt aacaccgtta
    19621 taaaaaatca aatctgcttt tgaagttttt tgaacatctt caggcaaagg ttcatattcg
    19681 tggggatctt tcccaatagg tacgatactg tgtaaatcaa ttttatcttt tgctatattt
    19741 tcggtaatat ctgctaaaat cgaattagta actactactt ttaatttttc gttcgaagcc
    19801 actttatctt tgtctttact atttattgaa catgccccga atataaaaag agcaatcaaa
    19861 atccccagac ttcccagtac tgctttccat tttctcatca taacgatctc tccttctttc
    19921 ttaaaaattt ttgttttggt gagattagaa aactaattac aaataagaat gccgctgtta
    19981 aaacaatact tgatcctgct gctatgttaa aactataacc aataaacaat ccaagcaatg
    20041 atgaacttgc tccgactgtt gcagaaataa atatcatagt tttcaagcta tttgcatata
    20101 aatatgctgt agctgctggt gtaattaaca ttgcaacaat taatatagtt cccacacttt
    20161 gcatagctgt tactgctact aaagttaata gaaccatcaa tagataatga taaaaactga
    20221 cattcatccc tattgctttt gccattaatg gatcaaaaga agtgattaat aattctttaa
    20281 aaaatagaac tactataacc aacactaaaa ccgaaacgcc aattgtaatc cacttatcaa
    20341 tatcttgtac agctaaaata tttccaaata aaatatgaaa taaatccgtt gagctatttg
    20401 caactcctat aaggataact cctagtgcta aaaaagaact gaaagtaata ccaattgctg
    20461 tatctccttt tattacacta ttgcttttta taaaagtaat aatgatagaa gctaatagac
    20521 caaatacaat cgcaccaata aaaaaattaa tacctaaaat ataagaaatt gctactcctg
    20581 gcaaaacagc atgagaaata gcatcaccca taagagacat tcctcttaaa ataataaaac
    20641 aacctactgt tccagaaaca atccctataa ctacagatgt aattagagca ttctgtaaaa
    20701 agtgaaagtc atacagacca ttaataaaat tttgaagcat attattcccc ctctccaata
    20761 aatatagtat ctccataggc tttttttaaa ttttcttcat taaatacaga ttctacactt
    20821 ccgtgagcaa ttagatttcg attcaaaaga ataatattat caaaatactt ctttaccttg
    20881 cttaaatcat gatgcacaat tagcactgtt tttccctgat gtttcaattt ttttaacgta
    20941 tccataatta ttcgttcact aactaagtct atccctacaa atggttcatc taaaaatatg
    21001 aaatccgcat tttgagcaag acatcttgct aaaagtacac gttgaaattg tcctccagat
    21061 aattctccta tttgatgatt agaatatttt cccatatcga ccttttccaa agcctttgaa
    21121 actctttgcc attctgcatt tttaattctt tgaaaaactt tcattccggc atatgttccc
    21181 atagatacac attcttttac ttttattgga aaagtaaaat caatatcagc tttttgctct
    21241 acatatgcaa tcttcaccag ttttttattg atatcttcat tattaatgga gacctctccc
    21301 tgatgaggga taatatttaa cattgcttta agcaatgtgg attttccagc accatttgga
    21361 ccaataatac ctgttaaagc accttcttgt atttttaaag aaatctcgtt caatgctaaa
    21421 aaatcgttat aacaaacatt aagctttttc acttctaaca taactttctc cttctaaatg
    21481 ataatgatta tcacgatcat atggtataca aaaattatat tttagtcaac cctaaatttt
    21541 atagtttaga tttttttctg ttgctgaaga ttagaatgac aaaactattt gaaactacgc
    21601 gtatagtaag tagctttcaa aatatataaa aaaggagcgt tctcaaatga gaacatgctc
    21661 ctaaaactac tttattggcg tatggaaaaa ttatacttga agtggatagc gggttgaata
    21721 agttgataag catcaaaaca tttataaaaa ttattcaaga ctatgtctgt tccatataca
    21781 aatatgaaaa tcagtaaact ccatttaact tttttcgtag tgtgtctttt tatacatgtt
    21841 tatcgttatt aatagtgaat aggaaaaaaa ctatttttga tcattgacaa ttaaatacaa
    21901 tttttgaata acgatccctg ctattcgagc tagaaactca agtacgccat gacctgatta
    21961 gcgacaaata cttagagatt tctttttgtt ctgggaaaac aaaatgccat gacaatagca
    22021 gcaaataatg atacttccgt aaggctcgcc gtaaactggg gagaggtgaa attcctatgt
    22081 gcttacccaa agcaattcaa aaatttcata actactattt taggagatga ttttatagaa
    22141 tccagagtct acctgaataa aaaacaaacc tgtgcatttc taggaatcga taataatact
    22201 ctagataagt ggattcgtat atataatttc ccagtaataa gagttggtgg tgtagttcgc
    22261 tttgacgtag aagatattaa agactttatg aatacattta aaataacttg aaattttctt
    22321 ctcgccgcat atactaaaat tagtgaaata tactgcctta ctttttttaa ggagtgagga
    22381 ttttgcctac aaagctttca aatgggaaat ataaaactaa tctgagatat ccaaaaaggt
    22441 ttaaagaaat aacaggaatt gcatcagaaa agtatcaaaa aacatttcca aataggcaat
    22501 tggcgattaa agccgaaaat gatatgaaga agaaaataga aaaagttttg agagaggaga
    22561 atgcaaactc attagaatta aaaggaaaaa taacgtttaa aaaattttac gaatctaaat
    22621 ggcttcctag atatgaatta ggtcaaacaa ttagatcaaa caggcctcct agtgatataa
    22681 ccattagtaa tacaaaagat atatttcggt tgcatatttt acctatgttt ggtgaatacg
    22741 caatgaatta tctaaatatc aatactgaga taatatcaga tgaattaacc aaaaaatcga
    22801 aagaatatgc aaatataaaa atcataaaag gatatgttcg ttccatgttc gatattgcag
    22861 aaatactaaa ttatatcgaa tttaatcgaa ctactaaaat tattcaaagt atcactgcac
    22921 ctaaaaaaaa tgctttagaa gaaaaaagaa tacaagaagg taagcaagca ctatcatcaa
    22981 aagaacttac taattggata gaagcagtaa atgatgattt taataatcat ttacttactt
    23041 ttcatgatta cacacttttt atgattaccc tgtatcttgg tgatagaaaa agtgagactt
    23101 acgctttgca atggaaatat attgattttg aaaaacaaac ggtccgtctt aaacatactt
    23161 tagataaata tcaaagaaaa aagtttacaa aaggtcgaaa agataccgtc attcaagtac
    23221 cagaagttgt aatgacattg ctaagtgaat ggaaatcggt acaagctgat caattgttga
    23281 aattaaaaat taagcaaacg ttagatcagt atctctttac ttatactaaa ccatctggag
    23341 aagtaaattg tcctgttcat gccgattacc taaactatcg aatcaattca attaaaagaa
    23401 ggcatcctga cttagttcat ttatctccac acaaactccg tcatacttat gcaactatag
    23461 ctagacaagg tggagcagat atgaatcaaa tttcaaatgc tttaacacac tcagatattt
    23521 ctacaacaaa gatatatgtg aacacaccag atatagttga taaggctgtt tttgaagctt
    23581 ttcagagagg attgaataag tgtgattgat atgtgttctt aaatgtgttc ttaaaaacaa
    23641 aagaagcact ttccaaataa ttgaaaagtg ccagaaacgt tgatatataa aggatattaa
    23701 cgttttgaga attgtgaagc tttacgtgct ttcttaagac ctggtttttt acgttcgacc
    23761 atacgtgcgt cacgagtaag taagccagca cgtttaagag ctaaacggaa gtcaggatca
    23821 acttctagca atgcacgagc gataccatga cggatagctc ctgattgtcc agcgtatcct
    23881 ccgccgttta cgttaacaaa tacgtcatat gcgccttttg tttcagtaac agcgaaaggt
    23941 tgattgatta cttcacgcaa gtcagcatgt ggaatgtatt cttcaacatc ttttttattt
    24001 acagtaattt tgccagttcc tggtactaga cgtacgcgag caactgcgtt tttacgacgg
    24061 cctgtgccga tatattgaac ttgtgccaat gaaattccct cctattagat taagtttgtg
    24121 atgtctaaaa cttctggttg ttgtgctgca tgtggatgtt ctgctccacc gtatacgttc
    24181 aattttgtaa attgtttgcg gcctaaagtg tttttaggaa gcataccttt tacagaagtt
    24241 tcgatcaaac gacgagaatt tttagcacgc aattcgccag cagtgattga tttcaatcct
    24301 cctgggtagt tgctgtgacg gtaataaatt ttgtcagtcg cttttttacc tgttaatttc
    24361 actttgtctg cattgatgac gatgacgaaa tcgccagtat ccaaatgagg tgtgaaagtt
    24421 ggtttatttt taccacgtag tacagatgca acaactgttg aaagacgtcc caatggaaca
    24481 tcagttgcgt ctactacata ccatttacgt tctacttcgc ctggtttggc catatatgtt
    24541 gtacgcacgt tattttcctc caatttaagt tctgatgttt gacatacact tcgagtttcc
    24601 ggggctcttt gtggggcaaa caataccatt taacatatta cccgctaatc tagtcaatgt
    24661 caacgttttt ctgcttgatt gaaaaattta tatgaaactt tacttctttt ctttctttta
    24721 tataaaaggg tcgtttcctg tcaaaatgaa aaacaaaaag aggctgtgac aaaagtcttg
    24781 tcacaacccc ttattttgaa taaacggtgt tctcctgcca actcctcggt cacaagtcac
    24841 aatatccata aaacataaga agctgttttt taaaattgtt tcttgtgact cggagctgaa
    24901 cggcaggctt acaacctctt ggtaaacggt gttcaatcag ctgaccctcg gtattagctc
    24961 aaaaaacggc aaaatatgag gaactatttt gacgtttgtt tctctaatac tcaggtcaaa
    25021 acgctgattt cacaacctct ttttcggtca agttcaacaa cagtttttac gcgtcgatct
    25081 ctggcgcttt gcccaaatga gcttggatca tccagatacg tttttctgtg gctgttttga
    25141 attcgataaa gatatcttgt gttggatcgt cgccttcttc tccagaaact tcgattcctt
    25201 tttggtaaag atctgctaga taacgatagc ctgcaacaag tgtttccaaa cgttctggaa
    25261 tagtacgatc ccagcggcca atttcatcag ggatttttgt gttatctgca aattcacgca
    25321 atgtagaata aggtgaaccg tctaatgtga tcaagcgttc ggatacttca tctaactgag
    25381 cgttcaaatc atccatgaac tcatccatca ttgggtgcaa tgtaaggaaa cctggtcctc
    25441 tcatgtacca atgtgtttgg tgaacaacaa cagacatttg gcttagatct gcaactaatt
    25501 gatttaatac ttctttggtt tgttggaatt tcatctttct tgcctcctaa cattttctta
    25561 cacttaaaat aatagtagac tttcaatgaa aagtacaaca aaatcattta cctgagaacg
    25621 attttcagtt cgctttttta tccgtaaagc caatcatttt tcagaatcag ctaattcttc
    25681 tcgcagttga gcaaattgct gataagtctg tgctaaatgc ttttgtgtcg aaacaaataa
    25741 tggatagatt ttctgatatt ttttatgatc agtttcttgt actccaactt gctctttcaa
    25801 ttctatcaat tcctgtgctt cactgatact ttggatcttt ccgatgcttc tccagcctaa
    25861 aatcacagct cctaatgcgg atgcttctgt gacagtaggg aaaacaagcg ggtaacccag
    25921 tacatcagcc atcatctgac gaaaaatcgg agattgagca aacccgcctg tagcacggat
    25981 ctctgtgagc tgattttcct ggcaaactcc ttttaaaatc cgataaaggt tgagacagat
    26041 cccttctaga atcgccttca tcatttcttt ttctgtatgt tgccgctgta aaccgataaa
    26101 actgccaaac gcatctgcgt cccaaagcgg tgctcgctca ccaagtaaat agggatgaaa
    26161 aatcagacca ttggcacccg ctggcacaaa agcgatagcc gaaagcagtg catcatatgg
    26221 attttctcct ttttctttag cagattgaac gacttcctgt aaaaatgtat gccctgccca
    26281 atcaaagatg ccagcaccat tgctagtcgc tcctcccact acccaatgtt tctgatccag
    26341 aacataacaa aacgtctcca tttctggatg gaactgaggc tgagtagtaa taaaacgaag
    26401 tgctccgctc gttcctacgg tcaaagcggc gatcgtatca ccaaaagcac ctaaccctag
    26461 attagaaagc ggcccgtctg cccctcccaa aacaaatgat atatcatttg gcaaacctag
    26521 ttctgctgct gtttttgatg gtagacctgt tacttgatag gtggaaggaa agacttgcgg
    26581 caattgctct attcgaatgt tcaagtagtc aagcacttct tctgcccatt ggaattcatg
    26641 gatatcaaaa tatccagttc ctgaagctgt tccgtagtcg ctgatcagtt cgccaaacaa
    26701 tctataaaag atatagtctt tgataccgac aaaataagca gtttttttga ataattcagg
    26761 ttggctgttt tgcagccact tgattttgtt caatggtgtc attggatgaa tcggcgtccc
    26821 agtctgccga taaaattctt tgccaagcac ggtatatttc agtttttctg cttcgtccgc
    26881 tgctcggtta tctgcccaag tgatcattcg agataacggt gttttctctt catccaacaa
    26941 tatcaggcca tgcatcgcag aggagaagga gacaaattga atgattgtgt ctgaaggcaa
    27001 ctgtttaatt acttctttta taacggtgca gacaccttga aagatcaatt cctgatcttg
    27061 ttctgccatc ccttgtgttt cttggatcaa agggtagcga aaataagcgg atgctgcttc
    27121 ttgggcttca tctgtgaaag caactgcttt ggtttgtgtg gttccgatat ctaatccgat
    27181 tgaaacgttc attttttcac ctcaaatttt atgtatgtac aaaaatttag tttaagcttg
    27241 cgtatcttgg ttttgaaaag ggggagatgg cgtgttactt tattttatca ttggttgctg
    27301 tatcggatca tttttatgtt taaccgccca gcggattccg ttaggtcact ctattattta
    27361 tcctagatct cattgtgtca aatgctgtcg ttcgctttct tggtatgaat tgattccgat
    27421 tctctcgatc atcgtccaac gatttcgctg ccgctattgc aggtgtcggt tgcccttcta
    27481 ctatttgttg gcagaagcct tatgtggtgg tctttttgcc tggttcttta ctttttcttc
    27541 cgcaagaaat ttttcgacgt tcatatggat gctttcggct ttgctatttt cgttgatgga
    27601 tttattttac ttcatggtcc attctcacac gctattctgt tcttgggcaa ttttatggat
    27661 tttttggttg caggccggcg tcttccaatg gcaaagtgtg ctgttaacgt ttatcgtagg
    27721 cggtgtgtgc cttcgctatg gtcaatccta tctcggagct ggcgatactc tgttgatgct
    27781 ttcttggagt ggtggcttgt ctctagaaga gttgcttcag atcttgtttc ttgctagtct
    27841 gtttggaata tccgtttttt ctgtttactt tatctgtcat aaaaaaaagt tggaaaagct
    27901 gcctttcatt ccttttttga gcagtgcgtt gctgattgtc cttcatctta ggtattgaaa
    27961 aaaggttgtg acaaacgact tgtcacaacc tctgatatat agtgttctct taccaaatcc
    28021 ttgtgacttg gagctaggcg acaggttcac aacctctcca ctaaatggtg ttcaatcagc
    28081 tgaccctcag tattagctca aaatgctggt tttacaacct ctgatatacg gtgttccata
    28141 agtagctttt tcggcttctt atttcttgac gccccaatgt cgacgaagga aacctgcacg
    28201 tccagaacct tctcgataaa gattgtaatg gagcttgttt ttcttgtaat aatcctgatg
    28261 gtaatcttct gcaggataaa attcgcttct tggttcgatt tttgtcacga ttggcttatc
    28321 gaatcgcccg ctgtcttgca atgcttgttt tgaacgctct gcaatatttc gttcttcttc
    28381 atcattatag tagatcactg gacgataaga atcaccgcga tcagcgaact gtcctaatgc
    28441 gtcagtcgga tcggtttgct gccaatagat ttccaccaac tgatcataag aaataacttc
    28501 tggatcatat tcgatctcta ctgcttctgt atgccctgtt gtgcctgttg ttacttgttc
    28561 ataagttgga tttggtacat gcccgccagt ataaccggat gtcacagaaa tgatccctgg
    28621 ctgctcttca aatggtttga ccatacacca aaagcatccg cctgcgaaaa ctgctttttt
    28681 tgtcatataa aatccccctt ttttctcatc ataccttgat ttccaaaagg aggataacgt
    28741 tttgcttgtg acagaaaaaa cggaaactat tatatacgtg atacggcttc tgataaatgc
    28801 caaaacgaac gtacttgatc aaaaacggtt aaatcaggaa tcacatattc agcagaagga
    28861 agatttatgt tttcacctat tcccaataca tgcatgttac cagccaaagc tgcttgacaa
    28921 ccagcttctg aatcttcaat gaccaagcat gcatttggcg gtacattcaa ttgctgtgct
    28981 cctttgagaa aaacttctgg atcaggtttt gcttttgata cttgcgtgcc gtcaataagg
    29041 acatcaaaat aacttgtcaa attcgttttt tctaaaatga ggcgtgcatt tttgcttgct
    29101 gatcccaatc cgatcttgat gtttgttttt ttcaagtact caagaacagc tattgcacca
    29161 ggcaaaacgg atgtttcatc cattttttga atcgcttgaa gatatagatt gtttttttgc
    29221 tcagcaaagg ctgatttctc tttttctgag aatttctgtt ccatttttcc aaatgacagc
    29281 aatcgctcta gtgactcggt tctggatatt cctttcagtt gctcgttttc tttctcagtg
    29341 aatggaatgg acagctggtt agctaaaacc agccacgctt cgtaatgata acgagctgtg
    29401 tctacaagaa cgccatctaa atcgaatagt gctgctttga ttttcatcga ttacctcctt
    29461 gaaaatgaac gacttgaagt aaagatgcga tgtttttagc tgtgcgatga agattatcag
    29521 tggcttgctg taaagcttct tgtaaaggca cagctgcagg aaggatcgga aaaacggccg
    29581 aaatgccaac atctgctgct ttttcgcttc ctttaccaac acttccgcaa atagctatca
    29641 caggaacgcc ctctggtact cttctagcaa tcccaactgg cgcttttcct tttagacttt
    29701 gtccatctag acgtccttcg cctacgatta cgaggtctgc ttgctgtacc cgtttatcga
    29761 actccagtaa atccaatacg tagtcgatgc cagagactat tttccctgaa gcaaatgcta
    29821 acagtcctgc acccattcca ccaccagcac tactgcccga tgcctcgatt acttgagggg
    29881 caaatctcat ataaaaatca tgcatggctt ggtcagccac tgctaattca ttttctttca
    29941 agcctttttg tggtccgaaa acaaaagaag cgccttcttt tccgcataaa agattagtaa
    30001 catcagtaat gacagtgatt ttggctttaa tcagctcaat aggcacgttc gttttatcaa
    30061 ctgtagcaat tttacctaga ttttctccca gtgcttctac tttttgatta tcttgatcgt
    30121 aaaaagcata acctagacct tctgccatgc cgatgccgcc atcgttggta ctacttccgc
    30181 caacgccgat gatgatgtgt cgaacacctt gttgcaacaa ttgtcgtatc agttctccta
    30241 ctcctcgcgt ggataaccta agtggctgtt gttggtttag tgggacatct ttcaatccga
    30301 cgatttctgc catttcaaaa atcgcagttt gaccgtctga agcgtactgg atttctttgt
    30361 ttttgccaaa tgcattagta acgactgctg tttgccgctt caaccttaaa ctgtctgcta
    30421 atgatgaaac cgttccttct cctccatcgc ctataggtag cagatcatat tcagcctgaa
    30481 caaaaacttc ttgaaaacct gattgaatgg cttgtgctgc ctctaaggct gtcagacttt
    30541 ctttgaaaga atctggcgca atcagaatac gcattatttt cccctccgtt ccaagatcag
    30601 ttctttttcc agctggtatt ggtctccatt gacaaaaata ggtaatgttt ctttcgtctc
    30661 tttttttatt actatttgtt tttttgtcaa aacaaatagc aacctgtgat ttttccaaat
    30721 aaaaggaaaa gaaatttttt cccatgctga aggaagtctt ggagaaatag aaagagttcc
    30781 attcgttact gtaatacctg aaaaaccaaa tataactgct agccatagtg ctcctaatga
    30841 agcagcatga attccgtcat ctgatgaatg cggatctggt cctaaatcaa tcaggcacgc
    30901 ttcttggaat aaatgatacg cccattccat ttcttggata cggcaagcct ctatggcgtg
    30961 aatcgcttta ctcaacgatg agtcgtggat tgttttgttt tcatagtaat gcaaattctt
    31021 agaaacgatt ggttgagaaa aatactcagg taataagtat aacagcatga caagatctgc
    31081 ttgcttgctg acttggagtt catttacttc gctacgggca taatcaagta aaatagactg
    31141 gctgccagga cgttctttgt aagtggtcaa atcaataact ggcttactga gatacgtgtc
    31201 atcttgcgga atcagctgtt ctttgttagg cactggcaaa tataacttat ctaaaaaatt
    31261 ttgacattct ttcaaaaaaa gcggatcgcc agcttgatat ttaacagcta aggccacatt
    31321 ataatgcgcc agatagttcg tatatgcatt attgtcgata tattctgtgt attcatctgg
    31381 accaatgact ctgtgtatct ctaaatgatc atcgactttt acagctctgc tcagccaaaa
    31441 agctgctgtt tcatgaatga gcgtttttcc ctttgtttct aaaaacgatt gatcctctgt
    31501 tgcttggaca tactcttgaa cggcataagc aaggtctgca ctgatatgat gttctgcggc
    31561 agctgaagca acttcttgtc ttgttccggt tttgatattc aatgcagcaa atttgggtgt
    31621 ctcttcctga ccagtgtgtg cgctttccca tgggaaaagt gcaccttgat agtgataatc
    31681 tcttgctttt tgccgtgcgc cttctaatcg atcataacgg tacagcagca aattctttgc
    31741 tacttcagga aactgatata aaaagaaagg caggataaaa atttccgtat cccagaaaac
    31801 atgcccttta taaccttcgc cagttagtcc cttcgcccct acactaacac ttggatcatt
    31861 gcggggagtc ataatctgta aatggtaagc agcgaagtcc atcgctaact gatcgaaaga
    31921 agaatcgcct tggatcgtta tccgatgctg atgccaaaaa tctgtccaat aagacatcga
    31981 ctgctctaaa atttctgtat aactaacgct tttctgggct tgggcaatac ctttcttaaa
    32041 cgggtctgtt tgctgaagag aggtagagag cacgatgatc ttctccagcg taaaggacgt
    32101 attttttctg atcttttctg aaaaggaagc ggtgatccgg cgattttttg cttggaatac
    32161 acctgcttta ttgaatttag ctgcaatccc aatatcaatt ttactttctg ttgtctggta
    32221 ggatgcactg atcaaatcgt caccaaatac tcgcagttct ttttcaacca actgctgtgt
    32281 accaaaattg gtttgctgtc catcgatacc cgttttcaca tctacttggc agtcttcggt
    32341 caacggcttg atgaccactt tcagggctgc ctgatggaga ttattttgat cagcaacacg
    32401 acaagtaatg acttccactt tttttccttg agcagtttca atgagcgcat agcgtttaag
    32461 ctctcccatt tctaaatcta gtgcccgctc gtatgcaaga actttcatcg tctcaagaga
    32521 aaaatgttca ccgtcgattt ttatttccca tctgatgaca tctgggagat tcactaactc
    32581 ggctgattct gctcctaaag gtcggttata tacaccagct gcaaacattc cccttacttg
    32641 attccgatag tcttcctcct ggcttcctct gataccaaaa aatccatttc caatggtcat
    32701 ctgactcgca tacttattga tatactctaa atcaaactgt ttttcttcta ctttcataag
    32761 gtaataactt ctcctgtttc tgccgaacga tataaatttt ccaccagatt ctggatgaca
    32821 tatccttgcc agccatctgc aatcatctga gtctggtcac cgagcgcccg attcacaaaa
    32881 tgagccatac ttagttcatg tgggtcatta actggcgtgg tcttttgtaa ggaaaccagc
    32941 tttccatcta catcttcgaa tagttcgcct ggatacagat tagcacctgc ctgatcgcca
    33001 caaaaagcca cattcagttt gtcttctctg atattcaaag caaacgaagt attcagttgg
    33061 atgatcttgc cgttttctaa ttccagtgtg ccaaaaattg catcttctac tgtgaatttg
    33121 cttggatccc atttcccgaa tttccctgaa ttttttttcg taccaatttt ttggaagctg
    33181 tacgcccgaa cgctttttac tttaggaaat ccagtaatat acatcgctgt atcaagcatg
    33241 tgaatgccat aatcgatcaa aggcccgcct ccttgaagtt ctttgtcgat aaacgttccc
    33301 cagcctggaa caccagaccg acgaagcgca ttcgcttcta cgtaataaat atccccgaga
    33361 acatcaagat gattcttgat cattgttgct tcgtcagaaa aacgatgctg gaatccataa
    33421 gccaaaatct gcccgttttt atcggctgtc tctgccatct ttcttgcttg atcagctgtc
    33481 atagctggtg gtttctcgca catcactgaa gcattagctt cgagggcagc caatacatgt
    33541 tcgaagtgaa agcgattggg tgtacagaca ctcacgatat cgggagaaat ctcattcagc
    33601 atttgtgtaa ctgatgtata cgcatgagaa aatcctgtac gtcggcaaaa gtcttctgct
    33661 cgctggctga ctggatcaac cacagcggcc aattctaaga catctgatct tttttgataa
    33721 taagcagcat gtactttttc tgctacttgt ccagcgccta tgattgctac tttcttcatt
    33781 tatttctccc tcctttgctt atttacttat tgttattctt tctctattct ttctctaaat
    33841 catttaaatg acgcgctgtt tccagacagt ttttcaagta ttgcaatgat tcctgataaa
    33901 ttttcacttc attttctcct cgcaaacgac attcatatac catataacct tcatactcat
    33961 tttgaagtag cgtttgaaaa tggcgagtaa aatcaattgc gccagatcct ggttggtagc
    34021 gatgattatc tgctaaatgg atatgaccca catactcttt ttgcgtagtc aatgcttttg
    34081 aaatatcatc ttcttcaata ttcatatgat aaaaatcagc gatgatctgc acatgtttca
    34141 attgattaga gtcaatgtaa tgacgcgcat ccgctaacaa attgatcata tggtcttggt
    34201 atcggttcaa aggctccaaa taaataaccg tacctgtttc ttcggctact ttatctaaat
    34261 aacgaagtga ttcgctgact gctttatagt ctccttcttt gcttcggggt gaaaccatcg
    34321 gcggtaatcg ataagtgaac attccccaag ctgctgggat aacgattcct ttgcctccaa
    34381 cctcgcttag tgcacgcaaa atctcagcaa tttgacgtac accattaaga cgccgttctt
    34441 cgataaagtc accgatccac ccatcgtagc cgttacaagc tgtcactact gggatccctg
    34501 tttctttgat tgcctgtttg actgtgtcga tattttctat taacaactta ccgtcgattt
    34561 cgtattcttc aaatccacag tctttgataa atctaaattt ttctaaaatg tctcttggga
    34621 aaaatgcttg atcttgcgta ccgaatttca ttgttctcct cctcggactt gaacgcccat
    34681 tttgatactt tcttctgggt gctggtctac ataacgcatg taagcttctg cgctttctgc
    34741 aaatggcaca actggatcaa tgatttcttc acaatccaag taaccgttca tcaataattc
    34801 ccaacatgtg tcctcgattc gtttacggtt ccatcttggg taatctgggt ttggttcact
    34861 agatgctcga gcaaagacga tttttgcatt attgaaatgt gcttcgcgac caagattaaa
    34921 cccagctgga aaaggtttag caaaggcaac ataagaaatg atcccgccat agccgatccc
    34981 tcttaaagaa gcttgtaatg cggcagcact gccactcgtt tcaataactg aatctactcc
    35041 acgtttatct gtcaattcct ttagacgaaa accgacatct gctttcatag gatctagcgt
    35101 gtaatcggca ccgtattttt ctgctaattc tctacgctgc gctatgggat cgatcccaac
    35161 gatggtagta gcacctgctt ttttagctaa ttgaatcgca atttgcccga tagcgcctaa
    35221 accgaagatt gctacagcat cacctgctcg aacatgtgct tcccggatac cacctaaagc
    35281 gaattgagca ggatcgtaac atactgcatt tttccattga tccaaccgat caagtttacg
    35341 tagtttataa ttatcaacac cgtttgtaat cagcgtttca cgaatgggtc cataagtgca
    35401 gactaactct cctttttgat actctgtcac caaactgccc gtttcttcga tcgtaccgac
    35461 aatcatattt cctaattgaa attcgccaaa taccacaccg cgttggcttc cttcttctct
    35521 tggcaagaat aggcgccatt cttctgaaaa ttcttcatcg ataaatggac ttaatcctct
    35581 aaagtcgaca atttctgttc ctggttttgg agtagcgaaa attactcgga tacgtacttc
    35641 gttcttttcg atctcacggt cttcgtaatc tttgaatccg gctattcttg gttctaatgc
    35701 aactaatttt ttcatctttt ctttcctctt tcttttcttt ttatcctttt acgccgcctt
    35761 cgactaaatc acctttaata aatcgttcag ataacgcata cataatgatg actggtaaag
    35821 cggtcaccaa tgaagcggcc atcattcgtc cccaaatgta gtctggtgta ctgaataatg
    35881 tgttcaaacc gattggtaaa gtaaattttt cggaggtcga caggaaaatc gaagcaaata
    35941 aataatcatt ccacgaaacc ataaagcaat aaacgaagac agaaatgatt ccagaaatag
    36001 ccaatggtat aatgatccga ataatgatct ggatccggct aagaccatcg atcattgctg
    36061 cttcttcaat atcagtcgga atcgtgtcaa aataactttt tagcatgaat atcgcagtag
    36121 gaagtgtttg aacgaccatc gtgataatca gtgctgtatt ggtatcatac aaacctagac
    36181 cggaaatgat tttaaataat ggaacaacga tcaaaatacc ggaaaacata taaacggtgt
    36241 aaaagctagc attgattttc gagcgagctt tgaagcgtag ttttgacaaa gcgtatgccc
    36301 cgctgatccc aatcactact gcagttacgg aggctatcaa ggagatcact aaactatttt
    36361 tgaaatacat gatgaatgga aaaatctcag cattgaaaat atcctgataa tgttcaaaag
    36421 tccattcttt cggaaaaata gtttgtgtcg ttgcaattgc ttcttgtgaa tccttgaatg
    36481 atgtcatcag catgatcaaa aatggaaaca aattgacagc taatagcaac aaaatcgtcg
    36541 cgtaaaataa gattttcctg ctctttttat ttttcatttc aagtccacct tctttcgtga
    36601 gagcaagacg accgctgcaa taatgatgaa caatagaatc gatatagctg ctgcttttcc
    36661 aagatcattg aacgcaaagg ctgtctgata caaataaacg cctaagatat tgactttatt
    36721 cgtcagtaga tagacatctg taaacatata gaacatccag atagatcgta aaacaatcac
    36781 agttgctagt actggtttga ttgccggcag tgtcacgatc ttgaacttct gccaagcatt
    36841 tgcaccgtcc atttcagctg cttcataaag cgttttgtcg actgtttgca aaatagccaa
    36901 aaatgaaata aacgcatacg gatagtatct ccagatagca aacaaaacga ccataaagaa
    36961 gctagcaact ggctggtcga accacagcgg tgcttcgttg aaaagctgca acctatctac
    37021 taacagatca ttgacgattc cataactatt attgaacata tatttccaag caaaaatcaa
    37081 agaaatagat ggcgtaacat aacttaataa aatcagtgaa cgcaccgttt tcctaaatct
    37141 gaacttgcgg ttaagcaaaa tagctacggc taatcctaaa gctgtactgc ctgctacaac
    37201 taagaatgtg taagcaactg ttaaacctaa agaacgataa aattcactat cacttaaaat
    37261 ttcaagataa ttgcttaatc cgataaaaac ggcgtctgag ttaggattca gcggcatatc
    37321 gaaaaaactg atctgaatat tggaaagcat tggaatcagc actaaaacag ctaataaaag
    37381 catgcttggt gctaaaagtc ccatggctaa ttttaagtca gaatgtttcc ttggacgatt
    37441 cattgaaacc tccccctgat aatctgccaa tagctatcta cttttttcga acaccattgg
    37501 cagaacttct tgttatttcg tatttttttg tgcgtcagct aaagcttgat cgacatcttc
    37561 gtttccgaca gttacttggt tcactgcttt tccgatcaca cctgagcttg tgatatctcc
    37621 cattttcgtg aaattctttt ccccgactag tccaaagact tgtacttcat caaaagcact
    37681 agcaatctca gatggcagct cgccaaaaga cttgatgact tcattttctt tgtaaccatc
    37741 cagttcgact acttgtttat tcactggttg agcaccacca ggagacatca agacccactt
    37801 ttccatgttt ttcggttgag ataagaaagc tgtgaatgct tcagcagcct ctttttgttt
    37861 ctcgtctaga ccagaagaaa tcgtcaatcc agatactgtg ccatagacag cttgatcttt
    37921 ttgtgttggg atagcaaaac cgatattttc tgagttcccc gcttcataaa cagaaggcaa
    37981 aatgtaagtt gaatagattg ccattggtgc tgttccattc atgaaagcat ctttgatttc
    38041 tgtcacatca ttagagcctg gcatcgtgta ttgggataag ttttgataaa acgacaatgc
    38101 ttctctcatc ttttccgtat cgatcgttac ctcgccttca tcatccaaaa catttgctcc
    38161 atttgacaaa gcaaattgag agaacgcttg ctcactcatt gttccttcag cagtaggcat
    38221 agcaattcca tattgtttat tctctttatc tgtgaaatgt tgagcaattt ttaaaatatc
    38281 atcccaattt tctggttctg aaaaaccagc ttctgataat ttttctttgt cataccaaat
    38341 accttgaacc cagccgctaa ttggtgcagc aatatagctt tttccatctt ctgaacgaac
    38401 aaggtttttg gctccgtcat aataattatc ttctccagct tcctcgataa cgttttggac
    38461 tgccgtctga tcaatcagtt catctttatc catcacttta gcaaaatcct gactgacttc
    38521 cattacttct ggtaatttac cggaacgagc taacgtaacg atttttgtat tgaacgctga
    38581 ttcttctacc ggcacttgct tgattttgat gtctggattt tctttttcaa aatcagcaac
    38641 cagttcattg atcacactta atcgttcctg ttcgacagaa gagtgcatga attgaatcgt
    38701 tgtctgttgt gattcgttag agctttgact ttcaccacaa gcagtaagaa gaaatccagt
    38761 agctagcaga caggtagtaa caataatttt tttcattttt ttccacctct tattttatta
    38821 ttttcagcca catatattca tacggctgga atatcaactt tcgttcttga ctgcaatgga
    38881 taatttgtcc agaaaacagg tctaggtaat ctccttttgg taaaagataa cctgctgatt
    38941 gattggaaaa attatggata actaagactt tctcttcctt cgcttcgcga ataaaactga
    39001 taaaagaatc tgctgagtcc agtaagtaaa tcaaactatt cggatggaag gctttttctt
    39061 tttttcgaat agatagcatc tgggtcaatt caccatatac tgctgttctt aatggatctg
    39121 tctgcaactc tttctcaata tctgctaaca aaaatttttg ccgattgatt tttcgattct
    39181 ctcctgtttt ttctacgcct ttgtaatcat ttcgacttcc cagcacactt tgaatataaa
    39241 ttgccggcac gcctggtaac gttaccaaaa atgaatgagc agctaaaaag cgtttgcttc
    39301 tccattccgt cgtatctgtt ggagaactta acgcatctag atacgtagcg tttatctcat
    39361 atggactggt cgttccatct gggtttttct tgtagtttac tcgggtaccc tctttcttca
    39421 gctgttccac taattcaagg atcgtttttt ccggcagaat acctcgtacc ggattcaatc
    39481 cgataccgtc atgggaggct aaaaaattaa aaaaagttgt ttttttcgat gcgaaatcga
    39541 tggtttttaa ccattctttc aacttacttg tattacccga acgaatcgct tgaagggtca
    39601 aaggtggtag cgaaaactga tagaccatct gtgcttcatt ctcgccattc ccaaaataac
    39661 tgatattatc tttgtgtggc acatttgtct cagtgatcaa taccgttcct ggagctgctt
    39721 catcagcgat tgcacggaat aattggatga ttttatgcgt ttctggcagg tgtatacaag
    39781 aagttcctag ttctttccat aaaaatccca cagcgtccaa gcgaataaat gaagcgcctt
    39841 tttctaagta aaacaaaaga atatcgatca ttttcaataa aacttctgga tttttaaaat
    39901 tcaagtctac ttgatcttcg ctaaaagtcg tccatacgtg tttttctttc ccgtttttgt
    39961 caatgaacgt tgtaagtaac gggctggtcc ttggtctagt cacgctgctt gtatctgtat
    40021 ccagtggcaa atcaataaaa aaatctttgt acgtatcatt caagtttaaa tattcctgaa
    40081 accaagtact ttcggcagac atatgattgc agacaaagtc gaacattaac cgtgtttcgc
    40141 ttctcatttc ttctatatct tcccatgtgc ccaaacggtc gttgattgcc tgataattta
    40201 caacggagaa accatcatca gatgtatatg ggaaaaatgg caagaaatgt acaactctaa
    40261 atgtatctgc caaatacttt tgataaaatt tcttaaatgt acgcaaagtt ggttgctgct
    40321 cttcaaaaaa ttgatcccca taagtaatca agaaaatatc ttcttcgtcc caatgcagtt
    40381 tgcctgcctg gcctttcttc tgctgataaa cactgacttt ttgttcaatc atagaggcgg
    40441 ttttctcaga caaatctgag tcgcgataaa tcgcttgtaa aagttttgta tacatcggat
    40501 tcccctttct tttttgggag cgttcccaac gatttgatca tattatggaa aacgcttact
    40561 gtcaatagca tttttttaaa taattttgat atacacaaaa atacaaataa gaaagcttat
    40621 gtatcaataa ttaatagctt cttaaaaaaa tatggtctct catgatcatg caagctattc
    40681 ctaaattttc aaaatcatag acaaaaaaga atgtctattg tactatggaa ttattctaaa
    40741 acgctcccaa aaaggaggtg catataaaat tgaaacctac tatttatgac attgcgaaaa
    40801 aagctaatgt ctcaaaatca actgtctcca gagtattaaa taaccagcca aatatctctg
    40861 ataaagcaaa agcaagtgta cttcaagcaa tcaaagaatt gaattatgaa ccgagcaaaa
    40921 ttgcaagagg actgtcagga aatggttttg acgcgattct agcattatct catcgtactt
    40981 ctcatacgac ctatggcaat cctttttttt cagatgttat tcaatccatt tctgccgttt
    41041 ctgaacaaaa taacttcgac ttgattctac aaacggcaaa aacaccagaa gaagagctag
    41101 aaaaatgcgc gaaaaagatc caagaaaaaa tgatccgagg aattattatt ttaagctcta
    41161 cgatggatga aacacttctt tttgaattgg atcaatacaa tattcctatt gtggtaatcg
    41221 gaaaagtcgg aaacgactac acgaacatct actcagtgga cacggataat ttccaggata
    41281 gttacgattt ggtggaaaca ctgatcaaga atggacaccg tcatatcggc tgtctccatg
    41341 ctccgacaga agtttatgta tccaatgatc gtctcaatgg ttaccgtcaa tgcttatttg
    41401 atcaccacct agatatccgt aatgaatgga ttatagacgg cggctttcgc ttagaagata
    41461 gcatggcagc aatgaatgat ttaatgaagc tacgagaaag accaactgcg attttttcta
    41521 ccgatgcatt aaaatcattg agtatttaca aagtggcaga acaatctgga aagcagatac
    41581 ctgatgatct ttcgatcgca ggattcagtg atcccttatt gtcctcccta ttttcgccac
    41641 agttgactcg gatagacatt ccgacaaatc agttaggaat caaagccaca gaacttttat
    41701 tccaactaat ccaccaccaa taccctgaag aaaaaagaat cattctttca accgagatta
    41761 ctctcacaga ttcgatccaa caacaagaaa tgtagaacag aattataaaa gaacagaaac
    41821 actgaggata agtcagttac tctgttcttt tttcaatcac tcatccctcg ttaccccctc
    41881 ccggtatttt agcgaatttt tcttattttc catctgtttt agatagctgt ggataactat
    41941 aatgtttgtg ttaaactatt ttttccacag ggaagaaaaa actattttta accacgttgt
    42001 gtataagttt ttatagttcg tttttttaaa cacatttacc cttatttcaa tccatgttat
    42061 ttggggatac ttatctctaa aacataaata gaataacaga catgtctact ggttttgttt
    42121 tattcgagga attattcaat aatagctagc aaaatattaa aaataaccgc tctatcttcc
    42181 catcaattta ttttgcattc aaaaaatgat ctatctttac ttttgttgat tgacttctct
    42241 tggaagatga tcgttccgat accttaattg gatacgaacc gatgttgtta agatcctttc
    42301 ccacttttct tctagttaga caaattattt tagacaaacc aaaaaagagg ttgtgacaat
    42361 aatttgtcac aacctctttt ttaaaatatc tattttgttt gattgttcat tgcgtcttct
    42421 gcagccattt gcgcttcaat atctgaaata ctgtagacat tttcgcttgc tacaccgact
    42481 tcttttggtt ccatgtcacg ataacgttgc ataccagtac cagctgggat gatcttacct
    42541 ataataacat tttctttcaa accaagaaga ggatctttct taccgcggat cgcagcatcc
    42601 gtcaagacac gagttgtttc ttggaatgat gcagcagata agaaactatt tgtttctaat
    42661 gatgcttttg tgatacctag taagacaggt cgagaagttg caggaacgcc tcctgagact
    42721 agcgtattgt agttttgatc tttaaagtct gcgatgtcta ataatgtacc tggtaagata
    42781 tctgtatcac ctggatccat tacacgaact ttacgcagca tttgacgaac cattacttcg
    42841 atatgcttgt cgccgatttc taccccttgc atacggtaaa cacgttgtac ttcacgaagc
    42901 aagtagtttt caacagataa tacatcgcga acttgcaaca attgttttgg atcgattgat
    42961 ccttctgtca atggtgcacc acggtggatc atatcgcctt ctgctacttt catacgtgct
    43021 gtataaggaa cagtatacgt acgtgtatct gtttttcctt tgattgttac ttctttggta
    43081 cgtgttgcag gatcttctga gatatcgatg acatcccctg ttacttctgt gatcactgct
    43141 tgccctttcg gattacgtgc ttcaaagatt tcttggacac gaggaagacc ttgagtgata
    43201 tcgtctccgg caaccccacc tgtatggaat gtacgcatcg tcaactgagt accaggttca
    43261 ccgattgatt gagcggcgat cgtaccaact gcttctccga cttcaacgtc agagccagtt
    43321 gcaaggttgc gtccgtaaca atgtttgcag acaccatgtt ttgtattaca tgtgaagaca
    43381 gaacggattg tcactgtttc gacacctgca tcaacgattt gttttgcgat gtcttcggaa
    43441 atcaattggt ttcctgcaat gatcaattca tttgtttcag gatgacgtac ttctttacgg
    43501 gtgtaacgtc ccactaaacg atcttctaat gattcgatga tttcatttcc ctcgcggatg
    43561 gcttggattt caagacctcg gtcagtaccg caatcttctt cacggatgat tacatcttgg
    43621 gccacgtcaa ccagacgacg agtcaagtaa cctgaatcgg cagtcttcaa ggctgtatcg
    43681 gtcatccctt tacgagcccc gtgagttgag ataaacattt ccaagacgga tagtccttca
    43741 cggaagttcg aaatgattgg caattccatg attcgaccat taggagcggc catcaaacca
    43801 cgcattccgg caagctgtgt aaagttggaa atgttaccac gagctccaga atcagacatc
    43861 atgaagattg gatttttcgc ttccaaacct tccatcagtt tttgttggat gctgtctttt
    43921 gcagcattcc aaacagcaat gacacgttca taacgttcgt catctgtgat cagaccacga
    43981 cggaattgtt ttgtaatagt ttcaacttgt ttatgggcat tttcaatgat ttcttgtttt
    44041 tcattcagta cactgatgtc agcgatccct actgtgatac cggcatgtgt cgaatgtttg
    44101 taccctaagt ctttcatacg gtcaagcatc ttagaagttt ctgttacttt gaatcgtttg
    44161 aagacttctg cgatgatgtt tcctaagttt ttcttcttga acggtaatac taattcttgc
    44221 tctttgatat gtgcaggaat atcagtacca gcttcaacaa agtatttgtc cggtgtttgg
    44281 acggtcaagt tgaagtctgt tggttcattc agataaggga attcaggagg catgatctcg
    44341 ttgaagatga tcttaccaac tgttgtgatc atcgtacgtt ctttttgcca ttcagtaaat
    44401 ggtttttcac ctaatgagtt agggttcaca ccgatacgtg aatgtaaatg aacatatccg
    44461 ttgcgccatg cgataacggc ttcgttttga tctctgaaga ccattccttc gccttcgcgt
    44521 ccttcttctt ccattgtcaa gtagtagtta cctagaacca tatcttggga aggagtaaca
    44581 actggtttac catctttagg gttcaagatg ttttgagcag ctaacatcaa catacgtgct
    44641 tctgcttgtg cttcttcatt caatggaacg tggacagcca tttggtctcc atcgaaatcg
    44701 gcattataag cttcacatac aagtggatgc aaacggattg cgcgtccttg tactaaaact
    44761 ggttcgaatg cttggatacc aagtcggtga agcgtaggtg cccggttcag caatactggg
    44821 tgttccttga ttacgtcttc taaaacatcc catacttcgt cttcttgacg ttcgatttta
    44881 cgtttcgcat ttttgatgtt tgaagctagt tcgcgttgaa caagctcacg catcacgaat
    44941 ggtttgaata attcaatggc catttctttt ggaagtccac attggtacat cttcaagaaa
    45001 ggtccaacaa cgataacgga acgacctgag tagtcgacac gtttacctag caagttttga
    45061 cggaaacgac cttgtttccc tttcaacata tgagaaagag atttcaatgg gcggttacct
    45121 ggtccagtaa ctggacgtcc gcgacgaccg ttatcgatca atgcatctac tgcttcttgc
    45181 agcatacgtt tttcattttg aacgatgatt ccaggtgcat tcaagtctaa caaacgtttc
    45241 aaacggttat tacggttgat tacacgacgg taaagatcat tcaagtcact tgttgcaaaa
    45301 cgtccacctt ctaattgaac cattgggcgt aaatctggtg gaataacagg gataacgtcc
    45361 ataaccatcc agcttggttg atttcctgaa gcgcggaatg cttctaaaat atccaaacgg
    45421 cggattgcac gtgtacgttt ttgtccttgt gcagatttca attcttcttt caattcggct
    45481 gcttctgcat ctagatcaac attatcaagt aattgtttaa tcgcttctgc acccatagca
    45541 gcttggaatt cttgtccata ttgttcacgt ttttcgcgat attcgcgttc tgtcaacaat
    45601 tgttttttct ctaaattcgt atttcctggt tcgatgacta catatgaagc aaaataaatg
    45661 atttcttcca aagcgcgtgg gctcatgtct aatacaagac ccatacgtga aggaatccct
    45721 ttaaagtacc agatatgtga aacaggagct gctaattcaa tatgtcccat gcgttcacgg
    45781 cgaactttcg aacgagtaac ttccactccg catcgatcac aaacgattcc tttataacgg
    45841 atacgtttgt attttccgca ggcacattcc cagtcttttg taggaccaaa aatccgctca
    45901 cagaacaacc cttcgcgttc aggttttaag gtacgatagt taatcgtctc aggttttttt
    45961 acttcaccgt aagaccagct tctgattttt tcgggagaag ccaaacctat ttgcatactt
    46021 tcgaatttat ttacatcgat caaaaggggt tccctccatt tcatttaatg gcaaaccgca
    46081 agacggctga tcttcgaccg ccttgcagct catagaccgg attagtctaa attatcttct
    46141 gcggtttcaa agttttggat gacatcgtct ttttcatctt ccacttgttc agcagctttc
    46201 ttttctaatt ctttggcagt ttgctgttcg gcaaattttg tcaaagcatc aacagtgatc
    46261 aaatcgtcgt cttcatcgtc catgtcgcga agttcgatct ctgtttcttc gatatccaag
    46321 acacgcatgt ccagacctag tgattgcaat tctttcacca atacgcggaa tgattccggt
    46381 acacctggtt ttggaattgg ttcacccttg acgattgctt cgtatgtttt cacacgtccg
    46441 actacgtcat ctgatttgta tgtcaagatt tcttgtaaag tataagccgc accgtaagct
    46501 tccagtgccc atacttccat ttcaccaaaa cgttgtccac caaattgagc tttacctccc
    46561 aatggttgtt gtgtaaccaa tgagtaaggt ccgattgaac gtgcatgcaa tttgtcatcg
    46621 accatgtgag caagtttgat catgtacatc acaccgacag acacacgtcc atcaaatggt
    46681 tcacctgtac gtccgtcgta cagaacagtt ttcgcatcgc tggccatacc ggcttcacga
    46741 actgtttccc atacgtcttc atcacttgca ccatcaaata ctggcgttgc tacgtggata
    46801 cctaactgac gtgcagccat acccaagtgt aattccaata cttgcccgat gttcatacgt
    46861 gaaggcaccc ctaaaggatt cagcatgata tcgattggtg ttccatcagg taggaatggc
    46921 atatcttctt ccggcataat acgggataca acccctttat ttccgtgacg accggccatt
    46981 ttatcccctt catggatttt acgtttttga acgatataaa cacgaactaa catgtttacg
    47041 cctggtgaca attcatctcc agcttcacga gtaaagattt tcacatcgtg aacgataccg
    47101 ccgccgccat gtggtacacg taatgatgta tcgcggactt cacgagcttt ttcgccaaag
    47161 atcgcatgca atagacgttc ttctgcagat aattctgtta ccccttttgg cgtgactttc
    47221 cctacaagca aatcgccatc ttggacttct gcaccaatac ggatgatacc catttcgtct
    47281 aaatctttta atgcgtcttc cccgacatta gggatttcgc gtgtgatttc ttcaggtcct
    47341 aattttgtat cgcgggcttc tgattcatat tcttcaatat ggatagaagt gtatacgtca
    47401 tcttttacca aacgacggct catgatgatc gcatcttcat agttgtaccc ttcccaagtc
    47461 atgaaaccaa ctaaaacgtt ttggcctaga gccatttcgc cttgttccat agatggtccg
    47521 tctgccagag tatccccttt ttcgactttc tcacccaaat gaacgattgg acgttggttg
    47581 tagcttgttc cggagtttga acgacggaat tttgttacat cgtatttatc taatgcaccg
    47641 ttgtcgcggc gtacgcggat ttcagaagca tcaacgtatt caacgacacc gtcatgttta
    47701 cataacaaag cagctcctga gtcatgcgct gatttgtatt ccataccagt accaacccat
    47761 ggtgcttgag gattgatcaa cggcactgct tgacgctgca tgttggcacc catcaaggca
    47821 cggttggagt catcgttttc caagaaagga atacatgctg tcgcaacggc aactacttgt
    47881 ttaggtgata cgtccatgta gtctacttta tcaatagata cttctaagtt ttcactttga
    47941 gcacgagcca taacaacgtc ttgagcaaat gttccatctt cattcaatgg gctgtttgct
    48001 tgggctacga tgtaatggtc ttcgatatca gctgtcaagt agtcgatttg gtcagtaaca
    48061 cgacctgttt cacggtctac acgacgataa ggtgtttcga taaatccgaa tttatttact
    48121 ttcgcataac tggacaaact attgatcaac ccgatgtttg ggccttcagg agtttcgatc
    48181 ggacacatac ggccatagtg ggagtagtga acgtcacgaa cttcataacc ggcgcggtca
    48241 cgagtcaatc cgccaggtcc taaggctgaa agacgacgtt tgtgtgtcaa ttcgccaaga
    48301 gggtttgttt gatccatgaa ctgtgacaac tgagaagaac caaagaattc tttgatactt
    48361 gccacaactg gacggatatt gatcaattgt tgaggtgtca atgtttcagt atcttggatc
    48421 gacattcttt cacgaaccac acgttccata cgtgctagcc cgatacggaa ttggttttgt
    48481 aaaagttcac cgactgaacg gatacgacga tttcctaagt ggtcgatatc atcgacattg
    48541 ccgatacctt ccatcaagtt caagaaatag ctcattgaag caatgatgtc ggctggacga
    48601 accgttttta cagctgcttc tggatagccg tttccgatca cgtttacttc acgttcaggg
    48661 tctcttggtg aaaatacttt gatgacttgg acagtcattg gatctgtgac cacaccgtct
    48721 tctgatggat agtaagtcac tgaatttagg ccattatcaa tgaaaggagc tagtgtttcc
    48781 atgacttggt gagtcagaac tgttcctttt tcaacgatga tctcgcctgt ttctggatca
    48841 actaatgttt cagctaatgt cagattcaat agacgtgttt tcaaatctaa ttttttgttt
    48901 actttgtaac gaccaacgtt tgctaagtcg taacgttttg gatcgaagaa acgagcattc
    48961 agcaagttac gtgagctgtc tgctgttttt ggttcgcctg gacgcaaacg ttcgtaaacg
    49021 tctttcaaac cttcttctgt tcttgagtcg cttgcgtttt tatgcaagtc tttttcgact
    49081 gtattgcgta atgtttcgct gtcgccgaag atttcaaaga tcgtatcatc ggaaccaaat
    49141 cctaacgcac gaactaatac ggttaaagga atcttacgtg tacggtcgat acgtacataa
    49201 gagatgtctt ttgcatcagt ttccatttct agccaagctc cacggttagg gataacagta
    49261 gaaccgaatc cttcttttcc gtttttgtcg acttttccat ggaaatagac acctggtgaa
    49321 cggactaact gagaaacgat tactcgctct gccccgttga tgatgaatgt tccttgttct
    49381 gtcattaatg ggaaatcacc gaagaatact tcttgtgctt tgatttcgcc agtctcgcgg
    49441 tttgtcaaac gcaatgttac atgtaatggt gcagagtagt ttgcatcatg cgcacgagct
    49501 tctgctactg tatactttgg ttctttcaat tcataatcta caaattccaa agatagattg
    49561 ccattgaagt catcgattgg caaaatgtct tcaaacattt ctctaagtcc ctcatctaag
    49621 aaccattggt aagagtctgt ttgaatttcg atcaaatttg gtaattccaa cacttcactg
    49681 attcttgcga aacttctacg ttcgcgatgt tttccgtatt ttactacgtg tccagccaag
    49741 ctcttcaccc ctctaaaatg tcattcaaaa agactacccg atcaattgtt acaataatat
    49801 ttcaaatatt atttttaggt aacaacagac attttttgcg gcttttaggc aaaaaaaaac
    49861 caaaaataga acattctctt gaaaccttac ttcgtgagct tctacttttg tttccttata
    49921 ttaaagccga aacggacaat atttcgtttc tgccttttct tcatcagata gtttttgcaa
    49981 cttcatatac tacacttatt ttctataaaa gtcaacactt cctggcgttt cttctgcttt
    50041 ttcgcaacat tttcttaatg ttttcaattt tatgttttca attatctgac aattcttaat
    50101 tgacagacct ttttatctcg gttatacttt agaaaattca ttttgtggag gaacttctat
    50161 gcgaaccaac atcaaccaaa tcgcaccaac acaactgaat aacttttact ttagctactt
    50221 tagataggtt tgtattcatc atgatggata caaacgttaa acgacagttt gtatctatga
    50281 tggctaaaga actttgtatt gcagcaaaaa gccacgtaga caaaatgcta agtggctgag
    50341 cagtgaaaat acaaagtaaa agtatcaagc attctacttt ttcaatttat tttccgactt
    50401 ttcaatccat ttggacattt tgtctgaatg gattttttgt ttcccaaaat taaggaggaa
    50461 aaagaaatga aaaaaaatat aatcatcgga ttaggcgctg ccctgctact agctttagga
    50521 ggttgcgcac aaaaagacaa ttccgcagag gcatcagatg gacaaaaaac aattggcgta
    50581 ttgcaacttg tacaacataa ctcgttagat gctgcctata aaggattcaa agaaggatta
    50641 gcagaagaag ggtataaaga aggcgataat ctaacaatcg attatcaaaa tgcccaaaac
    50701 aatcaagaca acctgaaaag tatgagtgag aaactcgtca aagaagatcc tgatttgcta
    50761 cttggaatcg ccactccagc agcacaatct ttattaaatg aaacaaccac tatcccgatg
    50821 actgtcacag cggtcacaga cttggaacaa gcccatttag tcacatccaa tgaaaaacct
    50881 ggcggcaatg tgactggcac gacagatatg gtgccaatcg aaaaacaaat cggcttactg
    50941 ttaaatatcg tgccagacgc caaaacaatc ggcatcatgt ataacaacgg tgaagcaaac
    51001 tctaagatcc aagctgattt ggcagaaaaa gaattgaaaa aagcgggcgt caaagtcaaa
    51061 gtactgacag caaattccac aaatgatgtc caacaagtga cgaaaagtct agctaaagat
    51121 gtagatggaa tctatattcc tactgataac acgttcgcaa gtgcggcaag tgttgtcggt
    51181 gaagtcgcaa aagaaacaaa aacacctgtc gttgctggcg cagttgatca agtcaaagac
    51241 ggcggtctag caacagtagg aatcgactac gaaagcttgg gtaaacaaac agggatcatg
    51301 gcagcaaaaa tcttagacgg caagaatcca agtgaacttc ctgtcgaaac agcgaatgat
    51361 ttggaactgt atgtcaataa agacatggcc aaagcattag gcatcaatcc agacagcatc
    51421 aaagaagctg aataaaacac aggaggattc tcatgacaaa tttgctctct cttttcttat
    51481 catctgcatc gcaaggggtc ttatgggccc tacttgcgat tggtgtatac gtcactttcc
    51541 gtatcttgga cattgccgac ttgactgctg aaggaagctt tcctttaggt gcagggatcg
    51601 cggcagtaag tattacaaat ggctatcatc cattgacagc ttgtcttcta ggctttttag
    51661 ggggtgcggc agcagggctt gtttccggac tgcttcacac aaaattgaaa attcccgccc
    51721 ttcttgcagg gatcatcacc atgactggtt tatattctgt cacatcccgt gtgatgggtg
    51781 cgccgaacat ctctttattg ggtcagccaa cgatctttca ttgggtcgag tcattcggca
    51841 taacaaaaga caacgctgta ctgatcgtcg gtctgctttt tgctttgatc gttgtatgtt
    51901 tacttgtttt gttcttacgt acagaaacag gacttgctat tcgtgcaact ggcgataatc
    51961 tggcaatgag cgaagcaaac gggatcaaca cagataatat gaagatcatc ggttatatga
    52021 tttctaatgg atgcattgct ctttctggct ccttgcttgc gcaaaacaac ggctttgctg
    52081 atttaaattc tggtattgga acgatcgtaa ttggacttgc ttctattatc atcgcagaag
    52141 ttttgttacg taaccagcca ctatttctcc gtctcttgac tgtcgtttta ggtgcggtca
    52201 tttatcgttt tattttagcg ttagtcttcg aactgaatgt tgaaccaagt gattcgaaac
    52261 ttgcttctgc tttcgtgcta gtgatctgtc tttctttccc gcagatccag caaaaattcc
    52321 atttacctca aaaaaagaaa ggcggtagtg tcaaatgaat gacgtcttaa cattggaaaa
    52381 tctccatcat acctttgaaa aaggaacgat caacgaaaat catgtcctga aaggcattaa
    52441 tctttcctta gatcccggcg acttcgtgac gatcatcggt ggaaatgggg ctggtaaatc
    52501 tactttgctg aacagcatcg ccggtacatt ttctgtcgat cagggtcaaa ttttattgaa
    52561 tggaaaaaat atcacgaaaa aatctgttgt cgaacgttcg aaatccatca gtcgcgtatt
    52621 ccaagatcct aaactaggga cagccgttcg tttaacggta gaagaaaatc ttgctcttgc
    52681 tatgaaacga ggaaaaaaac gcggcttctt ccgtggtgtc aaaccacaag accgaacatt
    52741 tttcaaagac cagctggttc ggctaaattt ggggttggaa aatcgtttat cctcagaaat
    52801 cggtttgctg tctggaggac aacgtcaagc tattacgtta ttgatggcca cattacagcg
    52861 tccagaactg atcttattag atgaacacac tgcagcgctt gaccctgcta cttccaaaac
    52921 ggtgatggaa ttgacagaaa agctgatcac tgagcagaat ctcactgctt ttatggtcac
    52981 tcatgacatg gaagacgcga tccgctatgg gagtcgactg atcatgctgc atcaaggaag
    53041 gatcgtcgta gatatccagc aagaggaaaa acagcagctc acagtgcccc aattattagc
    53101 gttgttcaaa caaaacagcg gcacggcatt aaaagacgat caagtacttt tatcttcata
    53161 atcagaaaga ggatgggaca aaaaatgaac gcccaccctc ttcttttttc tctttccttc
    53221 tttcgttttt gctttatgta tcaaccgttg tttcttcgaa aactattttg ttctctcctt
    53281 cttcctgata gaatggatgg gaaaggagct tgatgccatg acaacgaaag acaaggtact
    53341 tcaattattg aaaaagacac cagattttct ttccggagaa aagttggcac agcaactgga
    53401 agtttcccgg acaagtattt ggaaagccat caaagaattg gaaaaggcag gctatcgttt
    53461 tgagcacggg cctacagggt atcgttacct gccctctgac gtactagatg caaaagaaat
    53521 ccagcaagag ctacggtcgt ttattcctga tttgaaagta caaacgatgt tgacttctga
    53581 atctacgatg aaagatgcca aactggcagc agctcaagga gattctgttt cgaagttatt
    53641 tgttgctgat acacaagaac aagctcgtgg acgttttgga cggccttttt tcgctgaacc
    53701 tggacgagga atctacatga gtctcttgct ccatccagac aaacggtttg atgaattgcc
    53761 tcaatatacg atcatcgcag ccagtgcctg tgtgaaagcc attgaatctg taaccggtcg
    53821 ttctgcttcg atcaaatggg tcaatgatat ctacatggat ggaaaaaaag tctgtgggat
    53881 tttatctgaa gcagtcagtg atatggaaag cggcaggatc agtcatatca tcattgggat
    53941 cgggcttaat ttttctgttc ctcaaaatca ttttccagct gatctccaag aaaaagccat
    54001 ctctgtcttt cccgacggac aagctagtgt cacaaggaat cagctaatca gcaaaatctg
    54061 gcaagaattg ttcacttatc tttctcaccc agaaaaagcg ttggacttct ataaagaaaa
    54121 atcattcgta ttgggaaaaa ccgtgtcgtt caatcaaaaa ggaacgactt atgtcggtct
    54181 tgcaaaagaa atcggtgatc atggcgaact gatcgtccaa acaaatgaac agaagatgag
    54241 tttgtcttct ggcgaaatca gtctcacatc tatccgtacg caataattat cagatttcac
    54301 aaaaggacac ctgatctcat acagtgtcct tttttctgaa ttctcttcaa aagactctcc
    54361 ttattctatc agctgacagt ttctctatcc tctagaaaaa ggtattctaa aaatatctat
    54421 aaagcatggt acactttctt taaatgaatc aatgcaaaaa acaagagagt catcagttta
    54481 cacgatcaaa agagatagca ggccgcttcc tttttcaatc ttatagatag accatgggta
    54541 acgataaaaa caaaaaagaa cttgcgactt attttgccgt aagttctttt ttagctagtg
    54601 ccttaatctc ttaatcccaa caaacgtctc gcatagatca cctgaccaga gtgcatagca
    54661 gcatcatcaa taatagaaac gagacgcatt cctcgtgtga ctggtggtgt ccagttctcg
    54721 tcaattactt catctagctc ggaaggttcc agccttctta agtaagaaat agcaaaatca
    54781 gcagctcctc gcaagtatcc tagcagatct tctatttgat tagcttggat ctgctttgct
    54841 tgttccagac tatgcttcca atcttgttcg ttatctgcta tcgtcatcgg aaaccggctt
    54901 tcccagtctt gactatgcca aattggagaa gttcctgcta aatcagcaat ctggaaatct
    54961 aattctcgag cggtatgcca agccagccaa gtcattgatt tgatctgcgg ggctctatct
    55021 tccactggaa aacgattggc ctcctcaata gagacgcctt caaacaaacg ttcaaaccga
    55081 tcgtatgccc gatccacact ctcgcatagc atatctaaat aatccattta ttttcctcct
    55141 ttttatttat cctacttact ttttcctaat tctaggatac ctacttatat gttactacac
    55201 acccttattt tttacacttt aacagtcacc atcatcaata gtttggagat tgaaagaaaa
    55261 agatagtgtc gaactatcaa ttgaacaaga agcaacaata tgaacgtttc attaatattc
    55321 tttaaataaa caatgatttt tcaaacgaac agtttaagac taggagaaaa agagtataat
    55381 aggaaaatgt ttgaaaggaa aggaagggga aaaatgaaaa aaagggcaag tttactagtc
    55441 ctagttgctt tgttgttcaa tatcttttcg tatggtgtgg ccgtttcagc ggaaacatac
    55501 attcctaaag accctgggaa tatttataat gatctaactg gtaactatgg cttgttagga
    55561 attgctagtc aattccacgt atttgctaaa aataagacaa ctgtgaatgc acatacagac
    55621 ggaaatatag caacacatga acttgatgca aaaaataatt ttggtacaga gcttcatgaa
    55681 ggtttattga accaagaaat aaattatata caaaaaactg attctttcgc taattcttca
    55741 ggcataccta caggtagcac aagaatgaat aaatttgtcg ttggcagtaa cgtggatgta
    55801 gcacttcaag atggtcatcc tacagtcaat ggatccaggc ttgatcactt aactccagat
    55861 gatttttata aagatcgtgc tgggcatgaa tatattgatt tcgagcagga atttgctaaa
    55921 ttgaatgtag cagcaaatga tcttgcaacg atcactccag ctaaaacata tactgctgca
    55981 gattttccag acatgaacaa tcggacaatc gatttaactg atttatcaga taccgggttt
    56041 ttattggtaa atatcgatgc agaagtgtta acgatgaata cgccacttca aatcattaat
    56101 ccaaatgatc aagtagttgt atttaatgtc atcaacagtt cttctgcatt gaacgtacag
    56161 tcaccaatca aatacaatga tcgttcaaat catgaaacag aagatttttc ggatgcgaat
    56221 atctcttgga attttggaaa tgagatgact gatttgacaa tcagtgctcc ttttcaagga
    56281 acaatccttg cgcctaatgc tactatccgc attactcaaa accaagacgg aacgattata
    56341 ggaacaaatg tgattttaga tgcagctacc aatcgttggg atcctaacga aatatttatc
    56401 agcgacaatg gtacagatac gacagacaca agcgacagta cagatacatc taccacaagt
    56461 gatagctcag attcatcaac ttcaagcgac agtacagata ctacctctac cacaagtgat
    56521 agcacggata catcagcttc aagcgacagt acagatacta cctctaccac aagtgatagc
    56581 acggacacat cagcttcaag tgacagtaca gatactacct ctaccacaag tgacagcacg
    56641 gacacgtcag cttcaagcga cagtacagat actacctcta ccacaagtga tagcacggac
    56701 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
    56761 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
    56821 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
    56881 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
    56941 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
    57001 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
    57061 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
    57121 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
    57181 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
    57241 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
    57301 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
    57361 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
    57421 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
    57481 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
    57541 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
    57601 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
    57661 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
    57721 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
    57781 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
    57841 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
    57901 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
    57961 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
    58021 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
    58081 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
    58141 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
    58201 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg attgcttgtt
    58261 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
    58321 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
    58381 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
    58441 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
    58501 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
    58561 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
    58621 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
    58681 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
    58741 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtctcg ttttttcatg
    58801 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
    58861 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
    58921 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
    58981 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
    59041 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
    59101 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
    59161 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
    59221 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
    59281 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
    59341 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
    59401 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
    59461 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
    59521 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
    59581 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
    59641 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
    59701 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
    59761 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
    59821 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
    59881 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
    59941 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
    60001 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
    60061 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
    60121 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
    60181 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
    60241 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
    60301 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
    60361 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
    60421 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
    60481 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
    60541 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
    60601 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
    60661 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
    60721 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
    60781 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
    60841 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
    60901 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
    60961 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
    61021 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
    61081 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
    61141 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
    61201 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
    61261 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
    61321 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
    61381 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
    61441 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
    61501 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
    61561 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
    61621 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
    61681 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
    61741 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
    61801 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
    61861 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
    61921 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
    61981 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
    62041 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
    62101 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
    62161 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
    62221 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
    62281 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
    62341 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
    62401 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
    62461 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
    62521 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
    62581 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
    62641 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
    62701 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
    62761 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
    62821 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
    62881 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
    62941 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
    63001 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
    63061 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
    63121 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
    63181 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
    63241 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
    63301 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
    63361 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
    63421 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
    63481 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
    63541 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
    63601 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
    63661 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
    63721 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
    63781 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
    63841 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
    63901 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
    63961 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
    64021 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
    64081 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
    64141 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
    64201 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
    64261 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
    64321 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
    64381 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
    64441 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
    64501 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
    64561 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
    64621 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
    64681 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
    64741 ttttcatctg gacaatttgc tttggtagga aatctttggg ctatagcagc aatcgtatta
    64801 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
    64861 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
    64921 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
    64981 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
    65041 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
    65101 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
    65161 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
    65221 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
    65281 aagcttttga acaccgttta tca
//
LOCUS       DAFELK010000009        63612 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFELK010000009
VERSION     DAFELK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63612
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.009"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            1..369
                     /locus_tag="LP433_000762"
     CDS             1..369
                     /locus_tag="LP433_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBL2004950.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="LP433_000763"
     CDS             549..1490
                     /locus_tag="LP433_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBL2004951.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="LP433_000764"
     CDS             1559..2290
                     /locus_tag="LP433_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBL2004952.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="LP433_000765"
     CDS             2434..4614
                     /locus_tag="LP433_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBL2004953.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="LP433_000766"
     CDS             4634..5116
                     /locus_tag="LP433_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBL2004954.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="LP433_000767"
     CDS             5132..5893
                     /locus_tag="LP433_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL2004955.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /locus_tag="LP433_000768"
     CDS             6024..7358
                     /locus_tag="LP433_000768"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBL2004956.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7665..8150
                     /locus_tag="LP433_000769"
     CDS             7665..8150
                     /locus_tag="LP433_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBL2004957.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8143..8826
                     /locus_tag="LP433_000770"
     CDS             8143..8826
                     /locus_tag="LP433_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBL2004958.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8952..11597
                     /gene="polA"
                     /locus_tag="LP433_000771"
     CDS             8952..11597
                     /gene="polA"
                     /locus_tag="LP433_000771"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBL2004959.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11642..12478
                     /gene="mutM"
                     /locus_tag="LP433_000772"
     CDS             11642..12478
                     /gene="mutM"
                     /locus_tag="LP433_000772"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBL2004960.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12442..13071
                     /locus_tag="LP433_000773"
     CDS             12442..13071
                     /locus_tag="LP433_000773"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBL2004961.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            13123..13455
                     /locus_tag="LP433_000774"
     CDS             13123..13455
                     /locus_tag="LP433_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL2004962.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13767..14258
                     /gene="nrdR"
                     /locus_tag="LP433_000775"
     CDS             13767..14258
                     /gene="nrdR"
                     /locus_tag="LP433_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBL2004963.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14281..15654
                     /locus_tag="LP433_000776"
     CDS             14281..15654
                     /locus_tag="LP433_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL2004964.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15654..16580
                     /gene="dnaI"
                     /locus_tag="LP433_000777"
     CDS             15654..16580
                     /gene="dnaI"
                     /locus_tag="LP433_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBL2004965.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16709..17149
                     /locus_tag="LP433_000778"
     CDS             16709..17149
                     /locus_tag="LP433_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL2004966.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17293..17994
                     /locus_tag="LP433_000779"
     CDS             17293..17994
                     /locus_tag="LP433_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBL2004967.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17991..19112
                     /locus_tag="LP433_000780"
     CDS             17991..19112
                     /locus_tag="LP433_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBL2004968.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19127..20359
                     /gene="pepT"
                     /locus_tag="LP433_000781"
     CDS             19127..20359
                     /gene="pepT"
                     /locus_tag="LP433_000781"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBL2004969.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20491..21399
                     /locus_tag="LP433_000782"
     CDS             20491..21399
                     /locus_tag="LP433_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBL2004970.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21434..21706
                     /locus_tag="LP433_000783"
     CDS             21434..21706
                     /locus_tag="LP433_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBL2004971.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21717..22763
                     /locus_tag="LP433_000784"
     CDS             21717..22763
                     /locus_tag="LP433_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBL2004972.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23014..25623
                     /gene="clpB"
                     /locus_tag="LP433_000785"
     CDS             23014..25623
                     /gene="clpB"
                     /locus_tag="LP433_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBL2004973.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25774..26460)
                     /locus_tag="LP433_000786"
     CDS             complement(25774..26460)
                     /locus_tag="LP433_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004974.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26438..26932)
                     /locus_tag="LP433_000787"
     CDS             complement(26438..26932)
                     /locus_tag="LP433_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL2004975.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26952..28172)
                     /locus_tag="LP433_000788"
     CDS             complement(26952..28172)
                     /locus_tag="LP433_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2004976.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28319..30154
                     /gene="lepA"
                     /locus_tag="LP433_000789"
     CDS             28319..30154
                     /gene="lepA"
                     /locus_tag="LP433_000789"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBL2004977.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            30350..30922
                     /locus_tag="LP433_000790"
                     /pseudo
     CDS             30350..30922
                     /locus_tag="LP433_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            31335..31808
                     /gene="dfrF"
                     /locus_tag="LP433_000791"
     CDS             31335..31808
                     /gene="dfrF"
                     /locus_tag="LP433_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL2004978.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            31915..32445
                     /locus_tag="LP433_000792"
     CDS             31915..32445
                     /locus_tag="LP433_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2004979.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            32991..33233
                     /locus_tag="LP433_000793"
     CDS             32991..33233
                     /locus_tag="LP433_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBL2004980.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITSHKVK"
     gene            33230..33700
                     /locus_tag="LP433_000794"
     CDS             33230..33700
                     /locus_tag="LP433_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL2004981.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            33828..35042
                     /locus_tag="LP433_000795"
     CDS             33828..35042
                     /locus_tag="LP433_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL2004982.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECISYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            36031..36240
                     /locus_tag="LP433_000796"
     CDS             36031..36240
                     /locus_tag="LP433_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBL2004983.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            36352..37965
                     /locus_tag="LP433_000797"
     CDS             36352..37965
                     /locus_tag="LP433_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2004984.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGKVE"
     gene            38000..38347
                     /locus_tag="LP433_000798"
                     /pseudo
     CDS             38000..38347
                     /locus_tag="LP433_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            39343..39594
                     /locus_tag="LP433_000799"
     CDS             39343..39594
                     /locus_tag="LP433_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004985.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            39677..39949
                     /locus_tag="LP433_000800"
     CDS             39677..39949
                     /locus_tag="LP433_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004986.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            40039..40278
                     /locus_tag="LP433_000801"
     CDS             40039..40278
                     /locus_tag="LP433_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004987.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            40425..44708
                     /locus_tag="LP433_000802"
     CDS             40425..44708
                     /locus_tag="LP433_000802"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBL2004988.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            44807..45172
                     /locus_tag="LP433_000803"
     CDS             44807..45172
                     /locus_tag="LP433_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004989.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            45174..45626
                     /locus_tag="LP433_000804"
     CDS             45174..45626
                     /locus_tag="LP433_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004990.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            46240..47550
                     /locus_tag="LP433_000805"
     CDS             46240..47550
                     /locus_tag="LP433_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBL2004991.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            47573..47884
                     /locus_tag="LP433_000806"
     CDS             47573..47884
                     /locus_tag="LP433_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004992.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            48245..49501
                     /locus_tag="LP433_000807"
     CDS             48245..49501
                     /locus_tag="LP433_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL2004993.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            49498..50043
                     /locus_tag="LP433_000808"
     CDS             49498..50043
                     /locus_tag="LP433_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004994.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            50044..50544
                     /locus_tag="LP433_000809"
     CDS             50044..50544
                     /locus_tag="LP433_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004995.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            50625..51181
                     /locus_tag="LP433_000810"
                     /pseudo
     CDS             50625..51181
                     /locus_tag="LP433_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            51201..51545
                     /locus_tag="LP433_000811"
     CDS             51201..51545
                     /locus_tag="LP433_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004996.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            51564..52475
                     /locus_tag="LP433_000812"
     CDS             51564..52475
                     /locus_tag="LP433_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2004997.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            52554..53546
                     /locus_tag="LP433_000813"
     CDS             52554..53546
                     /locus_tag="LP433_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2004998.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            53543..53761
                     /locus_tag="LP433_000814"
     CDS             53543..53761
                     /locus_tag="LP433_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2004999.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            53774..54184
                     /locus_tag="LP433_000815"
     CDS             53774..54184
                     /locus_tag="LP433_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005000.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            54236..56764
                     /locus_tag="LP433_000816"
     CDS             54236..56764
                     /locus_tag="LP433_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2005001.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            56780..58990
                     /locus_tag="LP433_000817"
     CDS             56780..58990
                     /locus_tag="LP433_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005002.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            58998..60089
                     /locus_tag="LP433_000818"
     CDS             58998..60089
                     /locus_tag="LP433_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL2005003.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            60110..60652
                     /locus_tag="LP433_000819"
     CDS             60110..60652
                     /locus_tag="LP433_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005004.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            60847..61104
                     /locus_tag="LP433_000820"
     CDS             60847..61104
                     /locus_tag="LP433_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005005.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            61118..61450
                     /locus_tag="LP433_000821"
     CDS             61118..61450
                     /locus_tag="LP433_000821"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005006.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            61495..62043
                     /locus_tag="LP433_000822"
     CDS             61495..62043
                     /locus_tag="LP433_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL2005007.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            62050..62502
                     /locus_tag="LP433_000823"
     CDS             62050..62502
                     /locus_tag="LP433_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005008.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            62599..62934
                     /locus_tag="LP433_000824"
                     /pseudo
     CDS             62599..62934
                     /locus_tag="LP433_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        21809 a        10156 c        13620 g        18027 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggcagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttctcgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7561 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7621 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7681 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7741 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7801 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7861 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     7921 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     7981 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8041 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8101 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8161 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8221 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8281 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8341 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8401 tactctcttt tgaatggcat aatattagcg gttactcttg catactacga tattggaaca
     8461 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8521 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8581 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8641 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8701 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8761 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8821 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     8881 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     8941 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9001 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9061 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9121 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9181 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9241 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9301 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9361 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9421 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9481 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9541 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9601 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9661 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9721 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9781 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9841 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
     9901 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
     9961 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10021 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10081 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10141 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10201 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10261 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10321 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagaaaaa aaccaagaag
    10381 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10441 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10501 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10561 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10621 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10681 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10741 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10801 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10861 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    10921 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    10981 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11041 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11101 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11161 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11221 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11281 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11341 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11401 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11461 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11521 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11581 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11641 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11701 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11761 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11821 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    11881 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    11941 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12001 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12061 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12121 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12181 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12241 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12301 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12361 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12421 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12481 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12541 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12601 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12661 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12721 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12781 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12841 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    12901 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    12961 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13021 atacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13081 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13141 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13201 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13261 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13321 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13381 gaccacattc ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13441 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13501 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13561 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13621 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13681 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13741 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13801 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13861 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    13921 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    13981 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14041 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14101 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14161 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14221 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14281 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14341 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14401 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14461 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14521 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14581 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14641 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14701 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14761 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14821 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    14881 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    14941 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15001 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15061 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15121 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15181 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15241 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15301 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15361 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15421 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15481 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15541 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15601 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15661 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15721 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15781 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15841 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    15901 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    15961 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16021 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16081 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16141 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16201 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16261 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16321 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16381 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16441 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16501 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16561 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16621 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16681 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16741 tggtctattt tttcttttag caggctgcgg tagcgcagat agcaacacag gttctgttga
    16801 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16861 atttgtcgga acgattgaaa gtatcactca agtagaagca gaagaagaaa cgcttcagtt
    16921 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    16981 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17041 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17101 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17161 ttttcaaaaa taagaaaatg ttgttttata gaacgaaaag gtatattttt taaggagata
    17221 tgggaatttt tttattccta gtctccttat tttatttgga aaatgctata attatctaga
    17281 aggagtgaag ctatgaacca tttagattta tctcagcgct tagccgcagt gggtgacttt
    17341 gtccctgaat ccgctcgttt agcagacatt ggatcagatc acgcttactt acccgttgca
    17401 ttgatattaa gaggaaaaat cgaatatgca gttgctggtg aagtcgttca aggtccttat
    17461 gaatcagcac gtaagcaagt caaaaaagat ggattagaag accgtatcac cgtacgcctt
    17521 gcaaatggtc tagatgctat ccagccacaa gatggtatta cagctgtcac gattgcgggt
    17581 atgggaggtt cactgatccg agatatccta gaagctggca agttgaatca acgcttaagc
    17641 ggacaagaac gtttgatcct tcagccaaac atcggagagc gtacattacg atcttggctg
    17701 caagaaaatc agtataaaat ccaatcagaa aaaatacttg aagaaaataa aaaaatatat
    17761 gaaatcattg tagccgaaaa agaacaaaaa ccagttactt acaatgaaat ggagctgatg
    17821 ttcgggccat ttctgcttga agagaaaagt gagatcttca aatcaaaatg gacaagagag
    17881 cttcaacaaa gaaaagctat ccgtgaacag ctcaaacaag cagctaatca agaggcacgt
    17941 caaaaacaaa tcgagcagga aatccaaatg attgaggagg ttttaaagcc atgacaatca
    18001 gcggacgcac tttcatccaa aagtttgaaa gctattgtcc tcagtggcta gctgaagaag
    18061 gagacccagt cggactgcat atcggaacat tggataagcc aatccaacga gtaatgatga
    18121 cattagacgt tcgtccagaa gtggtcgaag aagcaatcaa gaaaaaaatc gatttgctga
    18181 ttgctaaaca tcctccaatc tttcgtcctg taaaacggct ggttactgat cagccacaag
    18241 aaaaaatgta tgcagatttg ttgaaacatg atattgccgt ctatgcagca cacacgaaca
    18301 tggatattat ttgggatgga ctgaatgact ggttttgtga acttctcggt attgaagtgg
    18361 agagttattt agtaaagact catgagattc attataaaaa actggccgtt tatgtacctg
    18421 tggatcatgc acagaaaatg cgtgaagtat tagctgcagc tggtgctggt acacaaggtg
    18481 attataccgg tacaagtttt acctcgattg gacacggtcg atttactccg gaagctggtg
    18541 cacaaccagc gattgggaaa gtagggaaga cagaacaagt tcaagaggca aaagttgagg
    18601 ttattttgcc ggaaactatc gaaaaacaag tgattcaagc catgcggtca gctcatcctt
    18661 atgaggaacc tgcttatgat cttttcgcta tagatgaacc agtcgaaatg tttgggttag
    18721 gacgagtagg tgaattgccg caagaaattt ctatagaggc atttgtagaa caagtaaaag
    18781 aagcgttcca actagatgga ctgagaatag tccagccaaa aaatgcaaaa tcctctgtga
    18841 agcgcattgc gatttgcggt ggaagcggtg aaaaatttta tccgcaagca atcgcccaaa
    18901 gagcagatgt ctatatcacg ggagatatct attatcatac ggctcatgat atgcaaagcg
    18961 ctgggttgat tgcaattgat cccggtcatt atattgaatc gttatgcaag caacgattta
    19021 tcgagaaatt tgaatcttgg aaacaagaag aaaattggga tattaacttt ttcgtttctg
    19081 aaacaaatac aaacccattt caatttaatt aaaaggagag aatactatgt acgaaaatct
    19141 tttgccacgt tttttacgat atgtcaaaac agaaacacgc tccgatgcaa caagcaaaac
    19201 gactccatcg actcagacac aagttgcttt tgcgcaagaa ttgaaaaaag aattagaaga
    19261 gttaggctta gctgatgttt tctataatga agataacgga ttcgttatgg gaacattacc
    19321 aagcaatgtt gatcatgaag tgcgttccat tggatttatt tcccacatgg atacagcaga
    19381 ttttaatgca gtaggagtca atccacaaat cattgaaaac tatgatggcg agtctacgat
    19441 cgtactagat gcggaagaac gctatacatt gaatacaaaa gattttccaa atttgaaaaa
    19501 ttatgaaggc cacacattga tcacaacaga tggcagtaca ttactgggag cagatgacaa
    19561 atcagggatt gcggaaatca tgactgcaat ggagatcttg atcaataatc cttctatccc
    19621 tcacggtacc atcaaagtgg cttttggtcc tgatgaagaa atcggtgtcg gagcggataa
    19681 attcgatgtt gagcaattcg atgtagattt tgcttataca gtcgatggtg gtcctttagg
    19741 tgagttgcag tatgaaacgt ttagtgctgc tcaagcaaat attacgatcc aagggaaaaa
    19801 tgtacatcca gggacggcaa aagatacaat gatcaatgct ctacagttag caatcgattt
    19861 tcataatcag cttccagccg atgaagttcc agaaaaaacg gaaggatacg aaggtttctt
    19921 ccatttgatg gcattggatg ggaatcctga agaagcttct atgagttata tcattcgcga
    19981 tcatgatcgt gaaaaattcg aagcacgcaa agcacaaatc acacatatcc aagaagagtt
    20041 gaatcagcga tttgatcaag aacgaatcaa agtagatatg tatgatcaat attacaacat
    20101 gaaagaaatc attgaaaaag atatgagcat cgtggaatta gcgaaacaag caatgatcga
    20161 gcttggtatc tctccagtga tcgaaccagt tcgtggagga acagatggtt caaaaatctc
    20221 ttacatgggt attccgacgc caaatctatt tgccggagga gaaaatatgc acggacgatt
    20281 cgaatttgtt tctttacaag taatggaaaa agcaacagac gtgattgtaa aaattgcaga
    20341 attgaacaca aagagttaaa atcgaaaaag aacagcttat gacaaggcgt tcgtcccaat
    20401 gatggaatgt catctgtcta aggctaaagg gcaggacaat ggaattggtt gtcccgccct
    20461 cttttttgaa gagtaaatag gaggtaaaga atggaaaagc tgctagtttt ttataacaaa
    20521 agttcaggga aagatgaggg tgagaaatta gcacgctggt ttcaagatta tgtaaaagaa
    20581 aagcagccag aattatatgt agaactagct gaaactggcc catcgattga tgatgcggaa
    20641 ttagtcaaga aagcagaagc catagaagct gatactttag taattatagg tggagacggc
    20701 acgattcatc atatcgtcca agcgttccaa aaaacattat ctcaatacca tgtcggatta
    20761 cttccaggtg gaactgtcaa caaccttgca cgtgttcttg agattcccct caaaaaagaa
    20821 gaagctgctg acgtgatcct ggaaggcaat gtacggaaaa tagactatgg tcaagtcaat
    20881 gatgaagtca ttatctctac actgacaatc ggaatcttag cagatacagc agtttggatc
    20941 agtcaagaag aaaaacagcg ttacggctcg tggatcttta tcaagaagtt ttttaagtta
    21001 ttgctgaaga agaaaaaata tcatttggat ttagaaacag acgaggagca ttggaaagga
    21061 aaatcccaac tgttgacagt cacgatgtct aactccgtgg gcggttttac aaattttgac
    21121 gactcagcga ccctagatga tggaaaattt catgtaacga tcgtaccttc cttagatatt
    21181 ttccgattta ttttttattt gcctagaatc atgagaggca aattctatac gatccccggc
    21241 attacttatt tcacagccaa acgcatgaaa atccaagcgc aggaaaaatc tgtgggcact
    21301 cgaacggatg gagacacgac agatgatctt ccagttgaat tatctgttgt atcaaaagga
    21361 ttaacagttt attcaccaaa gaaagaagaa aaagcttaga aatagtagtt aacagaaagt
    21421 tggaagaaga gtaatggatg tattgttaca caatcctttg tggttttacc ttttcattgt
    21481 gaatttttac ttattttgtc tgatggggta tgataaacat caggctagaa ctagcggctg
    21541 gcgtgttcct gagaataatt tgatatttgt cagcctgtta ggcggtggtt tgggaggatt
    21601 gatctctcga aaagttttcc atcataaaac tcggaaaaag aagtttacta taggattcgc
    21661 tgcaggtgta cttgttgatt tgattctcat ttattttttc cattaaggag caggagatgt
    21721 cgtctaaagg aacgaaaact aaaatcattc tgaatctgct tttgctgatt gtgatttttg
    21781 ccattattta ttatttaatc aatcaatcat ttgcagatat ctttgccgaa ttgctgtcta
    21841 ccagtgttgt tgttttggca gcggctgtta tattagggac agtttaccaa atcgctgaag
    21901 ggcgctcaat caaagaaatt gctgaacctt tcgcgccgaa ttttacaacg aaagatgggt
    21961 tcttgacctc tagctatatt gcgttttacc gaatcgtttc gtttggtaca ggaacgctga
    22021 tctcggagat ttatttttat aacaaaaaag gaatgaagct atcccaggga gcaggggtga
    22081 cagcactcca tatgattatg tacaaactgg cagtgatcac ttatgcatta gctggcttgg
    22141 tcatccaatt ctctcttttt tattctaatg gtccatcaat gatctggttt atcatcgctg
    22201 gtatcctttt gacgatcgtg attgttgcct ttttattggc gatgtccgtc agcttgaatg
    22261 ttcaaatatt ttttgtcagc ttatcgaata agttatttaa aagtgagcgt ttgcggaaat
    22321 gggtggatac atgcaatcag cagatctact ctttaaggga aacggtccaa accattatcc
    22381 aagacaggac tgcgctattg cggatttatc tatggaatat gttaaaactt gtattttggt
    22441 atgtacttcc ttatttgatt ctgattgaaa accatcctaa aatagatttt ctactgacca
    22501 tttcgtttat cagctttgca gtagtgcttt caggggttat tcctacgcct gctggtattg
    22561 gttcctttga atttgtctat ttgttattat tcagaccagt tgttggaaca gttgacgcag
    22621 tttcttcgct tttactgtat cgtttcagtt cctttatctt gccatttctc tatggatttg
    22681 tgtatgtgat tgctgaacgg cgaagagtga tcaaagaaga aataatagaa gtaaaaaaag
    22741 agaataaaga aaatcaaggg taggtctttt ataagatcta ccctttttat caaatcaaag
    22801 aaaaacgtta tggataagat aattttacgt ttgtttggct ctttttttat atacatacaa
    22861 tcaattttgt ttttttaaga tttatataag tcgagaaaaa aagtcaaaaa actatgtgta
    22921 tattttgacc aaaattgacc aaagcgatat aatagttttt gtaaagatca aagaaataag
    22981 tgatcttacc tttaattagg agggtatacc tgtatgaata ttgagaaaat gactacgacg
    23041 cttcaagaag cgattgctga agctcaacag attgcggtca ctcgaaaaca tcaagatatc
    23101 gacattgccc atgtatggaa aatcttttta caatctaatc attttggtcg aaatttctat
    23161 acggatgccg gattggatgt cgaatctttt gaacatgaaa ttgatcgtct actggatgag
    23221 tatccagttg tttctggtgg aaacgtccaa tatggacaaa acctcagcca gaatttcttt
    23281 cgattattga atgaagcaga ccaaatacgt gaaagcttcg gcgacgagtt tctttcaacg
    23341 gaagtcgtta ttttagcgtt gatgaaatta aaaaattatc cgttaactgt ttatttgaat
    23401 aaaaacggat tatctgaaaa agaattgcgt aaaaacatcg aagagatgag aggaggagaa
    23461 agagtgacct cacaaaacca agaagaacaa tacaaagcat tagaaaaata cggcgttgat
    23521 ttagtacagc aagtcaaaag cggaaaaatg gatccaatca tcggtcgtga tgaagaaatc
    23581 cgtgatgtca tccgtattct ttcacgaaaa acaaaaaata atcctgttct gataggagaa
    23641 cccggtgtag ggaaaacggc aatcgttgaa gggcttgctc aacgtatcgt acgcaaagat
    23701 gtgcctgaaa atttaaaaga taaaacgatt ttttcattag atatgggtgc attgatcgct
    23761 ggagcaaaat tccgtggtga atttgaagaa agactaaaag cagtcttgaa agaagtcaaa
    23821 aaaagtgatg gacgtatcct cttgttcatc gatgaaatcc acaatatcgt aggggcagga
    23881 aaaacagaag gaagtatgga tgccggaaat ctgttgaaac caatgcttgc tcgcggtgaa
    23941 ttacatttga tcggtgccac aactttagat gagtaccgtc aatatatgga aaaagacaaa
    24001 gcgttggaac gtcgctttca aaaggtatta gtcaaagaac caacagtgga agatacgatc
    24061 agtattctgc gtggattaaa agaacgtttt gagatccacc atggtgttaa catccatgac
    24121 aacgcattag tagcagcagc tactttatct gaccgttata ttactgatcg gttcttaccg
    24181 gacaaagcaa tcgatttgat cgatgaagcc agtgcaacga ttcgggtaga aatgaactct
    24241 atgccaacgg aattagatca agttactaga cgtttgatgc agttggaaat cgaagaagct
    24301 gcactgaaaa aagaatcaga tgatgcaagt aaaaaacgct tgaaaaattt gcaagaagaa
    24361 ttagctgaac ttcgtgaaga agcaaatgcg atgaagatgc agtgggaaac agaaaaagaa
    24421 gaagtcaatt ctgtttcagc aaaacgtgct gaaatcgata aagcaaaaca cgaattagaa
    24481 gatgcagaaa ataactatga tttagaacgc gctgctgtat tgcgtcatgg tacgatacct
    24541 caattagaaa aagaattgaa ggaattagaa gctaaagcaa aagacagcga gattaagatg
    24601 gttcaagagt ccgttaccga aaatgagatt gctcaagtcg ttggcagatt aacgggtatc
    24661 cccgtaacga aacttgtaga aggtgaacga gaaaaactaa ttaaattgaa tgaaacactt
    24721 cataaacgag tgattggtca agatgaagca gttgatgcgg tcagtgacgc ggtaattcgt
    24781 tcacgggctg gattgcaaga cccaaatcgt cctctaggtt ctttcctttt cctaggacca
    24841 actggtgtcg gaaaaaccga attagcgaaa gcgttagctg agaacttgtt tgactcagaa
    24901 gatcatatgg tacggatcga tatgagtgaa tatatggaaa aacatgctgt gtctcgtcta
    24961 gtcggagctc ctccaggcta tgtaggttac gaagaaggtg gtcaattaac ggaagctgtc
    25021 agacgaaatc cttatacaat cgtcttgttg gatgaaatcg aaaaagcgca tcccgatgtc
    25081 ttcaatatct tgttacaagt cctagatgac ggacgcttga ctgattcaaa agggcgagta
    25141 gtagatttca aaaatacggt tctgatcatg accagcaata tcggttcaca gttactgctg
    25201 gaaggcgtga ctgctgatgg aacgattcca gaagcagtgg ctgaacaagt caacacgcta
    25261 ttacgtggaa acttcaaacc agaattcttg aaccgaatcg acgacacgat tttatttaca
    25321 ccattgagcc tagacaacgt gaaaggaatc gttgacaaaa tggtggcgca attggcacaa
    25381 cgtctggaac atcaagaaat cctgctgaca atcagtgatg aagccaaaac gtggattgct
    25441 gaaaatgctt atgaaccagc atatggtgca agaccattga aacgatttat cactaaggaa
    25501 gtagaaacac cactagctaa agaaatcgtt gcaggacatg ttatgcctaa atcaaaagta
    25561 acgattactt tacttgatgg acaacttcat ttcaaaacag aagagctaga agaaatcgtc
    25621 taatcttcca ttgagactat aaaagaaaaa aggggtctga cacaactagt gtcagacctc
    25681 cttttttcaa ataaacagtg ttccagaagt agtttcttcg aaaaataagc cgaaatttct
    25741 tgaagctgcc cgcttctgtc acaacctctt ttattaggta tttttcactt tttctaattt
    25801 ataactttca aagtaacgct catctttttt actttgagac catgcaaaca atcccattaa
    25861 ggcagcacct atcgtatttg tcagcaagtc gcccatcgta tccatcaatg ctgctcgtcc
    25921 gacaaacagt gtgccatcag aagcagcaaa acgttgaaga ttcatgccta agaactggtc
    25981 gcataagaat tcccagaact cccaaaacac gccgcaaagt ccagcaaacg caaagccgaa
    26041 taagaggaac aaccaaggac tggtttttga tatctcagca tctttcatca agtaaccaat
    26101 caatccatag ccaagagctg tcaggaccat tggactcacc gcatgtaaga ttttgtccca
    26161 aaaagagatg atactgatca aatgcatccc tgtgcctaaa aagacagaga tgaacaagaa
    26221 aaaccagtaa aacaaaacga ttgctgctgg tattttaagt ttgaaaactt tcaaaatgac
    26281 ttgtggcatg aaaatcaatg caatccctaa taaagattcc acgataaatg tgattccttg
    26341 agaagtcgaa tatttttgtg tgataaattc ataaaaatta tagcagacaa cgaatacacc
    26401 aaaagcaagt aaagctattt gcaccttttt gatttcttta atcactgaaa gtccctccat
    26461 ctaaaaatct ttttacttct gaaagcaact caatttctga agaaaccact tttccgttca
    26521 atttgatcaa acctattgta tataagttca ggtagtgaaa ttgattttca gctgtttctt
    26581 gtagtgcagc gatttttttc gggtgggttc cgccttgctg tcgagtatca gtatataagc
    26641 cgatcactgg gatgcctttc gcataagcca caccgatttc cgatgctacc ccggcatcga
    26701 tcgtcagccc atctagtaaa gcaatcatta aatcactagc caacactttt tctgtgtcag
    26761 caagagcaat cattcgactg tctgcataag cagttttgtc attgattgct tcattttctt
    26821 gaggaagata gatcgaaagc tcagaagaga gctctctgat ttctttaact aactgttggt
    26881 tatataacaa atcactttta gcaaacattg gtgcggcaaa ataaattttc atctaaacat
    26941 catccttttt atcaaaaata atcgctaaag taagcttcca tgtttggaat gatacgctct
    27001 agtgacttca gtgtttcttc atctgtttct aaccgttcga ttcttgccaa ataagaagca
    27061 cggcgataat tcatcatcaa gcaagtcaat gtttggatat ccagtcgaac ggattttcct
    27121 ataggttcat ttaagacacg gacttgtccc tgttcatccc atgttaaagc gaagacacca
    27181 ttattccaag gagcgacagg atcttcaatg atgaaatgaa aagcatcagc tgttccaaca
    27241 aacggaaacc gttgaaggaa ttcttttaca tcaacgatcc gagccataaa atatggttcg
    27301 atctgctctt tgatctgact atcttcaatc aaaaatgcta aaggctcatt tttataaata
    27361 tctccatgta cccagtagat catggaaaaa tgtgcggaaa taaagttcca taagccattt
    27421 cgagcttctt gatcaagata gaacatttct tttacgtgaa atatttcttc agctacccag
    27481 tagaacagaa cacctcttgg ttcatggttg ctatcgtagt agacagcggc tgtgcgctca
    27541 tcttcatttt cgaaacgcca atactcttcc caatgaaaat cactgcggaa taaagcacca
    27601 tggttttgtt gggcaaattt gtcataaacg gaaaatacgt ctggatgatc aactggtaat
    27661 cgctcaacca taccacttac tgggatttgt ttaggtagct gtgtatctct gattttaaag
    27721 gaaagtttat cagacatgat ttcccatcct ttacgccgat agtaggggat actgtaagga
    27781 tacaaataag agatccattg cttattcttg cgcatattat ccaatgcaac gataattaga
    27841 tcttgcatca atccatggtt agcatattct ggataagttc caactccagt cacaccaccc
    27901 attttataac gtgcaccgtg aatattgact tcacaaggat agatagcgat ttgagagatc
    27961 agtttatttt cgtggaacca tccgaacact ttcgatactt ccaaaatcgg ttttttggaa
    28021 cggataaaag ctcgtttatt ctcaaacccg ctttcctcga tgtctgcttc agtcacttgg
    28081 aacacatagg aaagcaattc attgaattga tcgatatgtt cttgagtgac cggttttaat
    28141 tcaagatttt ctctaaaatc tttttgatcc attttttcat ctccatttat tagcttgata
    28201 acagtatagc aaaattctac aaaaaaaact tctatagctg actaattaaa aactctttaa
    28261 attactgctt ttcgttggta taatggaaag tgctgattat atgaaaagag gagacgctat
    28321 ggatataaag aaaatgaaag aacgccaaga gcagattcgt aatttttcga tcatcgctca
    28381 tatcgaccat gggaaatcta cattggccga tcgtatttta gaaatgacgc acactgtgac
    28441 gtctcgcgaa atgcaagatc agctgttaga ctcgatggat ttggaacgtg aacgtggaat
    28501 cacgattaaa ttaaatgctg tagaactcaa ttacacagcg aaaaatggag aaacatatat
    28561 ctttcacttg attgacaccc cagggcacgt cgacttcacc tatgaagtct ctcgaagcct
    28621 tgctgcctgt gagggtgccg ttttagtggt cgatgcagca caaggaatcg aagcacaaac
    28681 attggccaat gtttatttag cgttagacaa tgatttggag atcctgccag tcatcaataa
    28741 aatcgaccta cccgcagcag atcccgaacg tgtccgtcaa gaaatcgaag acgtaatcgg
    28801 aatcgatgct agtgaagctg tattagccag tgccaaatca gggattggga ttgaagatat
    28861 tctcgagcag atcgtggaat atgttcctgc accaagtgga gacttagatg caccgctaaa
    28921 agctttgatc tttgactcta tttatgatag ttaccgcggt gttgttctaa atgtccggat
    28981 cacggacggt atggtcaaac ccggagacaa aatcaaactg atgagtaatg gcaaaacatt
    29041 tgatgttaca gaggtcgggg tcttctcgcc aaaagcagtt gctagagact ttttgatggt
    29101 cggtgatgtc ggttatatca cagcaagtat caaaactgtc caagatacac gagtagggga
    29161 tacagtaacg ttagcagaca atcctgccgc tgaagcttta ccaggttacc gaaaaatgaa
    29221 tccgatggtt tattgtggtc tttatccaat tgatacttct cgttacaacg atttgcggga
    29281 agctttagaa aaactgcaat tgaatgatgc tgctttacaa ttcgaaccag aaacctctca
    29341 agcattaggt tttgggttcc gctgtggatt cctcggactt cttcatatgg atgtcgtcca
    29401 agaacgcttg gaacgggaat tcaatctaga attgatcacg actgcaccat ccgttattta
    29461 ccatgttaat aaaacggatg gtacgactgc tacagtagat aacccggcag attttcctga
    29521 acctgtaacg attcaggatg tagaagaacc attcgtcaaa gcacagatca tggtcccaaa
    29581 tgattttgtc ggtgcagtaa tggaactttc tcaacgaaaa cggggagaat tcattacgat
    29641 ggattattta gatgattacc gagtaaatgt cgtctataat attccgcttt ctgaaattgt
    29701 ctttgacttt ttcgacaaat tgaaatcaag cacgaaaggc tatgcctcat tggattatga
    29761 aatgtctggt tatcaaaaaa gcaagttagt gaagatggac atcttgctga atggagaaaa
    29821 agtcgatgca ttaagcttta tcgttcaccg agactttgcc tatgaacgtg gaaaagcaat
    29881 cgttgaaaaa ctgaaaaaac taatcccacg ccaacaattt gaggtgccaa tccaagcagc
    29941 tattggacaa aaaatcgttg cccgttcaga catcaaagcc ttgcgtaaaa acgtcttggc
    30001 taaatgttat ggtggagatg tttctcgtaa acgtaaactc ttagagaaac aaaaagaagg
    30061 gaagaagcgg atgaaacaaa tcggctccgt cgaagttccg caagaagcct tcatggccgt
    30121 tctgaaaatg gatgagcaag atagtgtgaa ataacttata atcaatcgaa aaacctatta
    30181 aataaacctt tttgagtaga tgcaacactg aggattatct gtataaaaga ttttaaactg
    30241 tcatttggtt atcacggcga tactaaaatt aacaaaattg gaatattttt cttgaagatt
    30301 tttagctgtc agtatatgat gaaagcatct cataggaggt gcttttttca tggttgataa
    30361 ttcaagtgga agggttctta aatctctaag aaaagagaaa aaactatctc aaaaaaagtt
    30421 agctgattta gcaggtattt cacaaagtac tttagttaaa tatgaaaaag ggtcaagaaa
    30481 aatccctaaa gacgtagata atactctaag caagattctg aatatagaaa ctctaataaa
    30541 agatgaggaa gataagattg agattctcat cggtaaacta attgcataca gagatatgaa
    30601 taagttactt aacaaagagt tagctgataa tataggaatt agtgaagtat tactcagtta
    30661 tgtgttaaat agaaagagaa atccgtcaaa agaaatgcaa aaaaaaatcg atatttttct
    30721 attaagtaat gaaaaagaaa ttttgaagga gattaatcgt gatagtgaga tatttagttt
    30781 atcaaaagac gataaaattg ttatgggaaa aagaatacga gaagtccgaa agaaccggga
    30841 agagacgctt gaaaaatttg gtaaaaactt taccatctat acaggcaaaa atgttataag
    30901 tagatgggaa aaaggtgttt cccaaacaaa aagatattaa gaaacagccc atgtttacct
    30961 gcttgcaaac aaaagaatat tgctactaga ctaagagata ctacataagt gtgttggtat
    31021 ctcttttttg ttgccgtgaa acagcagact atttcatttc tgcttgatta ccttaaaact
    31081 tattagtcta tggtttgtca agggcttgtt gcgtgagaaa tgctgaatat caccctttac
    31141 aaaacatagg ctgataagta acttttcaaa agcagaaaag aaatggcaat gcttataaca
    31201 atatgatata atgcagatga agacaaaaaa ggaatttgtc gagctggtta gttcgagata
    31261 attttgagtt tgttaagatg tggtgcactt gatggaatca caggtacgac atcatattat
    31321 ggaggatgaa atagatgata ggtttgattg ttgcgaggtc aaagaataat gttataggca
    31381 agaatggtaa tataccatgg aaaataaagg gagaacaaaa gcaatttaga gagttaacaa
    31441 cgggtaatgt ggttattatg gggcgaaagt cttatgaaga aatcggtcat ccgttgccta
    31501 atagaatgaa tattgttgtt tccaccacaa cagagtatca aggagataat ttagtttcag
    31561 ttaaatcatt agaagatgca ttattattgg ctaaaggacg agatgtatac atatctggtg
    31621 gatatggact atttaaggaa gctttgcaaa tagtagataa aatgtatatc acagaagtag
    31681 atttaaatat tgaagatgga gatacattct ttccagaatt tgatatcaat gattttgaag
    31741 ttttgatagg ggaaacactt ggtgaggaag tgaaatatac gagaacattt tatgtaagga
    31801 aaaaatgaat tgagtaaatt ttggatttag ggtgttttca taaatatatt gctttttatg
    31861 catatataaa ttgttgtaag acaaattcct gtttgtattt ataaaagaga aaaaatgaga
    31921 aaagtagttt tatttattgc catgagcctt gacggatata ttgcggacgg taatggtgga
    31981 gtagcttggc taaatggtca tggaaatgac aatgaaaaca tcgacactta tacagaattt
    32041 accaaagata tagatactgt cttaatgggg tggaatactt ctcatcaggt tgttactgaa
    32101 ctttctccgc aagaatgggt atataataaa tttacaactt atgtattaac acataaagag
    32161 tgcaattctt cccaacaaat tcattttaca agtgaaaatc ctgttttatt attggaacgg
    32221 ctaaaacaag aagcaggaaa ggatatttgg atttgtggcg gagcaaatct tgttcagcag
    32281 ttggtaagca aaaatatgat tgataaatat tacatttctg ttattcctac tctgttagga
    32341 aatggggttc gtcttttggg caacatagac agggaaataa agttaaggct ttgtaaaaca
    32401 cagacttata acggaataac cgatttgatt tatatgcgta gataactaga gagaaacaga
    32461 aaagctgtta aaccgacgga gcgatccgac cacgttggcg ggaaaatcct taagattttt
    32521 ccgccatgct tgcaaggggg cggttcgctt cggcggttcg gcgagcttgc gagccgttca
    32581 aagcccccgt tatctaacaa ggggggcaca aaaaacaaga aacactatac actaacaagc
    32641 ggaaaacgct gtatttataa ggcaaaaccc catttttaca gtagtgatat aaattgtacc
    32701 tatatcacta tgaaaattga atagtaaata tgagaaagac agttgatttc aaaaaataag
    32761 aaattgattg tcgttttctt ttgcagaaat ttaagtgcag gcaattatgg tagttgtcgt
    32821 aattgctgtc agctcagtgt ttatcactga tggtgtgaaa gatttacggt tggagatgtt
    32881 caataagatt attggtgctt aattattttt attgtagtgc tgatatgaga atgttataat
    32941 tggggtataa aacatacaaa taaatttgct gaaaaatgag gtatcaaaat atggaaaatg
    33001 aattactgga aaacttagga agacttcaca caactgaact tggcgttatt agaattaaaa
    33061 agaacttatc tttgaatgta gaaaatgtaa ttgaatggtg caaagaaaaa attagccttt
    33121 ctaatgcgga aatcacaaga aaaggaaaaa actggtatat aacgattgat aattgtatta
    33181 taacggtaaa tgcgtacagt tataccgtta tcacttctca caaggtaaaa tgataaattt
    33241 ttctataaag gaattaaacg catttgcagt tattgggcag gaagtagaac tgactaatta
    33301 tcaaaaaaag aatattcaga ttagtacaca gttttggaga aagtttaaca gtagtttgaa
    33361 aaaagcgtat ctttcacaat caggaaattg ggtaaaatat gcttttatgg aaagaagaaa
    33421 tggaaaactt tattatttct gttctattcc ccaaagaacc attaccccag agggctttct
    33481 gtataaagaa ataccgtctt ataaatattt ggttgtggag catattggtg ctatggataa
    33541 aatatatgaa acttatggca agatttatga agaaattatt cctagtacat cgtatattcc
    33601 tataaaagat attatcctac actttgaaaa atacgattat cgttttcatt ggaatagtga
    33661 taattcagtt attgaaattt ggatacctat tcaagattag aagcaatttt atatccatac
    33721 acacaaagca gttagtctta ggattgactg ctttttctat acagattttt aatgacaggc
    33781 aattatcaat tatggtagtt gccttttttg attggaggaa ttgaagaatg aatgataaaa
    33841 actttattga agaactaaga caaaagcgtg aggaatacgg agtaacacaa acaaggcttg
    33901 ctgttgcctg tggtatcagc cgtgaatatt acaaccgcat tgaaaaagga aaacagccat
    33961 tgaatgacga attaagagaa atcatagaaa aacagattga gcgtttcaat ccgcaagaac
    34021 cactattctt attgattgat tactttcgtg tccgctttcc tactacggac gcattggcga
    34081 ttatccgtga tgtattacaa ctgaaatcta attacatgct ttatgaagat tatggaaaat
    34141 acggatatga aagcaaatat gtacttggcg acatcaatat catgtgttcc atgcaggagc
    34201 atttaggtgt tttattggaa ctgaaaggca aaggctgtcg gcaaatggaa tgttatctac
    34261 tggcacagga acgctcatgg tatgacttca tgctggattg tatgacggct ggtggtgtga
    34321 tgaaacggct tgatttggct atcaatgata aagcaggaat attggatatt ccaaagttaa
    34381 aggaaaaata caaggctggc gaatgtatct cctacttccg tatgcagaaa gattacagcg
    34441 gtacagaaaa atgcggtagc gatttaccaa agaatacagg agaaacctta tatctcggtt
    34501 caacaagtag cgaattatat atgtgtgctt atcagaaaaa ttatgagcag tatgtcaaga
    34561 atggcacaga aattgaagat acggagatta agaaccgttt tgaaatacgc atgaagaacg
    34621 aacgagccta ttatgcggtt gtagatttac tgacctatcg ggacgctgaa cgcaccgctt
    34681 tttctatcat caatcattat gtccgctttg ttgacagaga ggacgacaag ccaaaaagtc
    34741 aatggataac aaatgatgat tgggcatggt ttgtagggga aaacagagag ccgatacgct
    34801 taaccacaaa gccagagcct tacactttac aaaaagcgtt gcattggcta caaagacaag
    34861 tcgcaccaac cataaaaatg gtacaggcat tagacagaga aaatcgtaca acgatactga
    34921 aagatatgat tgagcaggca gaactaaaag acaagcataa acatttatta caattagaga
    34981 aatcaaccat agaagaacgt atagataccg ctgttccaca agagaatgac ggtatttttt
    35041 aatgtaattg aaaaatttca gatttagtca gcaaagagct gttttcattc cctatgtgaa
    35101 gtgaaagaag aaaaataaat tttttattaa atctgcaaca aaatggctac ttgcgtacag
    35161 atatggtgcg agaaaaggaa atctaaactt tttttgaaaa taggtcatta aatcggggct
    35221 tgctgtccct atatgaagtg aaagaagaaa aaagttttga aaaaatgacg gaaattcgtg
    35281 attagtggac agtcttctgt gaaaagagga aaaacatcat cattttgtat tcaaacaggc
    35341 attagcagtt gagtgttgat gtgaaaagat gaaaatactt tgttctcaac ttaacaattt
    35401 aaggtttccg ttccctatat ggtgcaaaga aaatatttca ttctattgtt ggcagtaacg
    35461 gtatggtttg ggtagttagg gtgtgaaaag gaaaatattc ttttttcatc atcaacttag
    35521 caaaatgaca ttttctatcc ctatatggtg catgaaaaga agttaaaatt tttccattta
    35581 aacttagcaa atggacgttt gctgtacaga tagtagtgaa aaaggagaaa atcaaccgtt
    35641 gattgccaaa atgaaccgtt ccatttgtac taataatgga aaaagttttg gattttggtt
    35701 acgtttctcc tcttttccaa cgcgatatat aggaaagacg atttttttct ttcaatcgtt
    35761 ctttgacaac tgaataaagt aattcaatac gtttgacaga cagctagccg ttgaaacaaa
    35821 tacgccacga cctttcccct gcaagagcga gcgaaaacct atttgtgttc ttgtaaaaga
    35881 tttgtcctct tttatcgcca tgacctgtac tgtcagataa tgatactccc gtacagccac
    35941 agcttgagca ttaagagcgt cgcacgcaat gggtacggct acataagaac tatgcagagg
    36001 tggaactcct gtgggctatg acaaaagccg ttgaattgct tagaaagatt ttacagaaag
    36061 ggggtatgtg ttattgataa tgctgtaaaa acaattcaaa agaaaaatgg caagtgtggc
    36121 attggcaaca gaggaaagac aaagattgta gtaaaagagc atttttccga aaagggcaaa
    36181 acaatggaag aacttctaac tgatgtcatg ctggaaaaag caaagcagac aatcgcataa
    36241 aatcggtgca gttgtaagaa atagattgaa tgacaaaaag tacccgtgtt atactttact
    36301 tgcaagcagg tattgtaaac acgggttagt tataaaggag gataactgac aatgaaacaa
    36361 cagatttaca atactgcact ttatcttagg ttaagccgag atgatgaatt acagggcgaa
    36421 agttccagca ttaccacaca gagaagtatg ttgcgtttat atgcaaaaga acatcatttg
    36481 aatgtcattg atgaatatat tgatgacggc tggtcgggaa caaattttga cagaccgagt
    36541 tttcaaagaa tgattgagga tatagaggca ggaaaaatca actgtgttgt aacgaaagac
    36601 ctttcccgtc ttggcagaaa ttatattatg acaggacaat atacagaatt gtatttccct
    36661 agtcataatg tccgctacat agcgattgat gacggtgtag acagcgaaaa aggcgaaagt
    36721 gagattgcac catttaagaa catcatcaat gaatgggtgg caagagatac aagccgtaaa
    36781 gtcaaatcag catttaagac aaagtttgcg gagggggctc attacggtgc ttatgctccg
    36841 ttaggatata agaaacaccc tgacatcaaa ggaaaactgt tggttgatga tgaaacaaaa
    36901 tggattattg aaaaaatctt ttccctagcc tatcaaggtt acggaagtgc aaaaatcaca
    36961 aagcagttaa gagcagaaaa agttccgaca gcgtcatggc taaattttac aagatacggt
    37021 acttttgcac atatctttga gggaaaaccc gaaagtaagc gttatgagtg gacgattgct
    37081 catgtcaagg cgatattgaa aagtgaggtt tatatcggaa acagtgttca caatatgcag
    37141 tctacggtat cgttcaagag caaaaagaaa gtgcgtaagc ccgaaagtga atggtttcga
    37201 gtagaaaaca ctcacgagcc gattattgac aaggaagtgt tctatcgtgt gcaggagcag
    37261 ataaaatcaa gacgcagaca gacaaaggaa aaggcaacgc cgatttttgc agggcttgtc
    37321 aagtgtgcgg attgtggttg gtctatgaga tttggaacga ataagacaaa taaaacgcct
    37381 tacagttatt atgcttgcag ttactacggg cagtttggca aaggtaattg ttctatgcac
    37441 tacattcgtt atgatgtgct gtatcaagcc gtattggaac gcttgcagta ttgggctaag
    37501 gcagtacagc aggacgaaga aaaggtattg aacaagatac agaaagctgg caatgcagag
    37561 agaatacggg aaaagaagaa aaaggcaagt acattgaaga aagccgagaa cagacaaaat
    37621 gagattgacc gtttatttgc gaaaatgtat gaagatagag cctgtgagaa gataacagag
    37681 cgaaattttg tgatgttgtc cagcaagtac caaaaagaac agatagaact ggaacagcag
    37741 ataacaagcc taagagaaga actaagtaaa atggaacagg atatgatagg tgctgaaaag
    37801 tggattgagt taatcaagga atattccgta ccaaaggaac tgacagcacc attattaaat
    37861 gccatgatag aaaaaatcct catacatgaa gcaacaacga atgaggataa cgaaagaata
    37921 caggaaattg agatatatta ccgatttatt ggaaaagttg agtaatcaac aagagtaata
    37981 tttttaacta agggaaaccg gtattaatat tccagatatt gaaaaactaa tgaatattgc
    38041 ctatcttggt aaggtcactg ttccttacct tatgtacgga gaagattata agaatatact
    38101 tccaaaagat gaaagagtta gcgattttaa aaagataaat tcttttagta tgggattaag
    38161 gatgaggaaa attaggaaag attattatct agaaagggag gagtttggaa agcttttttc
    38221 tccttcaatt tcaaaatggt ccatagatag gtatgagaat ggtagagata tacccaatac
    38281 taatcgaatt atccaatatg cttatatagg aaatctttct ttagaatttt tgatttacgg
    38341 gatataaaaa tagtttacgt cgatacttat taagttatcg acgtttttta ttatagaaaa
    38401 aatttataaa aggaggtttc ttgatatgat aagaaacaaa aagggtttgt tgaaagttgc
    38461 tttactggca gcttttttct aagtaacttt ttgacaagct caatggcaac acaagcggaa
    38521 gaagtaatac aagaactaac tgttatgaat aacagctaga taaaatgggc tatgtatgtt
    38581 atccaacaat ttagtaatca ctagaagcct agcgaaagtt cgcttgataa gttatagatg
    38641 agtattgatt tgtagtgttt ccaaatcaaa agggtacaga gccacatgaa atatgttgtc
    38701 ctctgcagcg tcaggatggg aatccatacc atggagattc ggagatctgt gagggaatac
    38761 ttacgtggtt aatatgtcag ttgtgttgga cgtagtaatg gtcatagtgg gtagattgac
    38821 tgaattctta tatgagaaaa tgaaaccaac aagaagatag ggttatttat acagaattgg
    38881 ggatcttttc tggaaaagta atcggataat gcgagattcg tacggtcttt tttaaatttc
    38941 tctaaaaaaa acggcatcga atgggttggg tgattgataa gcaatgaatc atagactgat
    39001 atagaataaa aaatgattct atttatcttt ttacatctat cgttttttca agtagccgca
    39061 aattatatca gcattcaaca atttttgtat acaagttcta gtaaaaggat ctgaagaaaa
    39121 agttggttgt tgtgaagata aaaaaagaat caggttttac tgagtttttc ttcaaaattt
    39181 gtgttattag gttaggacaa agataagaag aagtatgaag atttaaaaaa ggaatgagga
    39241 aaagatagta atttccgatt attggagttt ttttatttat aaagaagaag cgaataagtt
    39301 gtgattccta gatttcgcgc gtgattaatt aatgagcaaa aaatgcggaa agttttagtg
    39361 tttaatacac gaggacaaag tttcttaggt attgaaggca cacgtgtaac ggttgatggg
    39421 tggtgtgatt gtttcgaggt tggaaaacat gttgaactta tggcatttac tgagctaaaa
    39481 gataagaaca acgtggaatt tttcgagagt gatattggtt gggacgatca tgaagaagtt
    39541 tatggaaaat ttattttgcg gaagggaaat tcttatacga atggggaagc ataagtagcg
    39601 atttgttaga gatcattgat aggattgaaa ttgtcgggaa tatttatgag aatctagagt
    39661 tatttgaggt gatagaatga gtgatggttt tgaacaagta tcaataatta aaaatcaagt
    39721 tcgggagatt cttagaaaaa aaggctattt ggtagatagt tattttgaag gagattacga
    39781 aacatgggta ggtgtctatg ctcgtccaga gaataaacct acctatttag atcctacgac
    39841 gtcagaagat gcctatttac aaaataggta tcgagtagat ggttttaagc aagactttgc
    39901 ggagtggttt gaatgggaaa ttgaaaacgg agaagtaaaa gaagaataag agtacttgtt
    39961 gtatcaaaat aagccagtag aacaaccaaa ccagtagcta gtaatgacaa taatactgag
    40021 gaatcggatc attatggtat gattgatatt tctcttccag aagatcttaa gccagatcct
    40081 gtaacaattg gcaatagtgt catgattttt gattcattag atgaagctat gtcatatggt
    40141 tggaaagaaa ttaaggatga aggtagtaat tggtatggca tgagatttgg tgatggtgaa
    40201 gttgccaaaa aagctggtat tccaattggg aaatggacag ttgatttcca cgaagcaggt
    40261 tctttttttg ttctgtaatt atagtgggag ggtaaaatca ttgatgaaat gtgttcagat
    40321 aagagcgcca gataaaaata gaagagacag ttcacgtcgt tatcactttt ggtaacggcg
    40381 ttttgtttta ttatataaaa ttctcaggaa aaggaggaat tcttgtgtat gcaaaaacga
    40441 aaatgaattg gttgaaagca ctcgcattgg tggctttttc tcaattctgt ttcttggtgg
    40501 gaactgctca agcacatgca gaagaaacga cggctataca acctacgatg gaagccattg
    40561 cccaagtcgc ttctgaagtg acagaagtcc aaccagcaga agccggggtc ccagctggtg
    40621 aagccactgt tgaacaggcc cctgtgacag aagcgccaac ggtcaattcc aaaacgactc
    40681 tcgatcagac gattggggaa acacaacacc cagggaatag tcctggtact tcacaaccag
    40741 ttgaagaaac tgcctcaatt acaacccctg cttcagaaac gtccactcta gaaggagaaa
    40801 aagctgccga agcaacgcct tctgtgcagc cagagtcttc tgagaaacaa gcggaagaaa
    40861 agaaacgaat agaagaaaca gtggaacaac cagcggctac tgctgacaaa gaaggaaaaa
    40921 atgaggaaaa cgttgaaaaa acaatctctt caaccgcagc tagtcaaaat caaccaacga
    40981 aaccaaacaa agaatctacg gctagtattg aaaatcaaaa gaaaaaagag cagaacattc
    41041 caaaaacagg tacacctaca ctgttagtaa cagtaccaac caatcgttcg gttcgtgttc
    41101 gccgtgcaac caatgcagct gttttaggtg gtcggaaaat tgattggggc gaaaatattg
    41161 gtgttacttc tagtccgaac aatctaaact tcactttaaa ttatatggtt cgttttgaga
    41221 ttaatggaca agtggcgttt tgtattgagc ctggtgtctc agccgcagaa ggtcaagttt
    41281 atacagctac tgctttgaaa aactatttga aaaattcaaa tgtacggaaa aaaacaagct
    41341 tgatctctta tttaggatat gtcacaaata aagacaaatc cgatgaacaa tacattgcgg
    41401 cacaatttat gatttgggaa gctttgggca caaaaatccc aatcaaaaat atacgtgttg
    41461 attatgatcg tcgaaaagca gaaattcaac gtttgattaa taactttggt gaaaaagcaa
    41521 cttttaataa tcaaacacat acggtaaaaa ttggcgaaac gttgaaagta aagaataaaa
    41581 atgatttttt gaaatatgtg aaagacattc aaaaaccaaa aggtgtcaat gtatctattc
    41641 acggcaatga agtatggatt acagtcacaa aagaggcacc ggataaagca aaaattcaat
    41701 tgaataaaat taaagttcaa ggtgcgccat tagcctatcg tcgtccagga gctcaaacaa
    41761 ttggtgtgtt acatccaaca gaacctaatg cgtctgttat taatttacaa attctaaaac
    41821 aaggaaacat tcgtgtgttt aaagaagatg cggaaactgg tgtgaaagca caaggtgcag
    41881 cttctttaga aaatgcggtc tatggtttgt atcaagcaga tgggaaaaag attaaagaaa
    41941 ttaccttgaa aaaaattaac ggcaaagtac aggcagaaat taaagatctt gatcctggca
    42001 aatatgtttt aaaagaaatc aaagcgccaa aaggttatgt gctttctgat gaagcaattg
    42061 aaattgttgt tgaacctgga aaaactgtca atgcgaccgc aaaagatcaa gtgatcaaag
    42121 gaaccattga tttagtgaaa gttgctaata aagatttagt cgattcaacg aatccagata
    42181 acaaaccaaa attagctggc attgaaatca ctttgacgtc aaaaacaact ggcaaagtgg
    42241 tgaaaaccgt tgtgacagac aatgatggtt atgctacttt tggtaaaaat accgttgtct
    42301 ttgatacgta cattctttct gaaaccaaag gaaaagaagg gtataaacta tttgaaccac
    42361 ttgaagtcac aatttctgaa aatgggcaaa ctttccatta tgttttagaa gataaagtaa
    42421 ttgaacaacg tcttaaagtg gtgaaagtgg atcaagaaac aggaaaagtg attccacttg
    42481 ctaatacaga attcaagatt tttgatactt tagccaatcg ttatgtcaca atggagattc
    42541 caaatgatac agaaacaacg gatatcttta aaaccaatga aaaaggcttt ttcctaacta
    42601 acggtacact tacttatgga aaagatcgct atcgtttgga agaaatcaaa gcccccgtaa
    42661 attacgtttt gaatcaaaac ccattagtgt tctcgattac caatgataca gaaccgatca
    42721 aagtgatcca ttttgcgaac cgtcaagcac ggaaaagtgt aaaattattc aagtatgaag
    42781 aatggaacaa gaagaaaacg ccgctcgcag gtgtgaactt taccttgtat aacggtaaaa
    42841 atcaagcaat tggtgaatat accactgatc aaaacgggga aattttagtg aaaggtctag
    42901 ttgccgatga ctattacttc ttggaaaatg ccccattaga aagtttccaa ccaaatacag
    42961 ataaacaagc attcacggtt gcattcaaac aaaatgcgcc agatgatggg gaaacgttag
    43021 tggtttctgt acgtaattac ttgattccac caaaactaga aacacaagcg tcaaataaag
    43081 ccgatggtga aaaagtggtt gatccattag aaacgatcgt cattaaagac agtgtttctt
    43141 ataccaactt gtttgtcgga aaagaataca ccatttcagg agtattgatg aacaaggcaa
    43201 cgaatgcgcc aattttacaa gatggcaaag aaatcacaag taccttggcc tttattgcag
    43261 acaaagtcaa tggcacaaaa gaccttgaat ttgtggttaa tgctagtgtt ctgaaaggtc
    43321 aaacgatcgt tgtttttgaa aaacttttcc gtgatggcat tgaagttgca gcacatgcgg
    43381 atatcaacga tgaagcccaa agtgtgaaag tgaataatcc aaccgttcat accacggctg
    43441 tctttgaaga cggattgaca gtcgcagacc caacaggatt gtttacctta aacgataccg
    43501 ttgaaattac cgagattctt ccaggaaaag catacttggt caaagggatc ttaatggata
    43561 aagcaaccgg tgaacccttg cttgtgcatg gaaatacggt agaaacgagt gttggcttta
    43621 ttgccaaagc agaaaatgaa acggtgatcg taccatttac ctttgatttg acaggtataa
    43681 atggtcgtga aatcgtcgtg tttgaaagtc tttttagaaa tgatgaagaa ctagcaaacc
    43741 ataaagacat caacgacaaa gggcaaacgg tacgagtaac taacccaagt gtacgtacaa
    43801 cggctacaca taaacccact ggcttgaaag aggttaatcc attaacgaaa gtcaccatta
    43861 cagacgctgt gaaataccac gatttggtcg ttggaaaaac atacacagtc aacggtgttc
    43921 taatggacaa agtaacggaa aaaccagtgc tagtagatgg aaaagaagtc acaagtacct
    43981 taacgtttgt ggcagaaaca acggatggta cagtcaatct agactttatt ctagacgcac
    44041 gtgcgttgcg aggcaaagaa gtcgtggtct ttgaagatct gtttagagaa ggcgtattat
    44101 tggcttctca cgcagatatt accgacaatg accaaaccat caaaatcagt aatccaacca
    44161 ttacgacgaa agcgacgaat aaaaatggcg gaaaagagat cttggccttg ccaaatcaaa
    44221 ctgtgcttga atgggtcaaa gtagacggtc ttgcgattgg tcaaatctat cgcttaattg
    44281 ttcaaggcta cttaacacca gacggcacac catttgaagg cactcatgcg gaaaaagtct
    44341 ttgcggccga taaagaaatg atggaattct tatttgaatt cttagtggac ggtcgcaatc
    44401 ttgcaggaaa aggcttgagt tttgcggaat ggctccaagc gaaaacggaa gatgagaaag
    44461 aaacgtttga agaagtggcg aaacacaatg tagatctaac aaacaaagat caaacggttc
    44521 aaattgtgga agcgccaaaa ccaccgcaac cagtgaaacc agaacaacgg gttaaaccag
    44581 ctactgttgt accaatgttg ccaaaaacag gtgaacaaac aagtagtata cttatggttc
    44641 ttggattagt agtattagtc attgctttag gtataacact ttataaagta cgtaaagcca
    44701 aagattagtc atgaggaaca agcggttagg atttttaacc gcttgtttga ttgtaatgta
    44761 gaaatattta gaatttattt tggtttttaa gaggaggaaa aactttatgg cagaaaaagc
    44821 attgcgtatg aagaaagagt ttttaggtca agtattttta ttgggttcac gggaacctaa
    44881 tccaccaaag gaaattaatg gtgtgtctgg gcgatatgtt caattacaag cagagtgttc
    44941 gcgagaagaa cagcctgctt tttttgttta tctcacagct gaagaggata aaagattacg
    45001 attaccagaa aaagaggtgc gtatttcatt tgaagaagct tattttgttt ttcgtaaaga
    45061 acgagtgaat agtcgtgaaa caaatgatat gggacaaaca gagcgtcgaa caactggcta
    45121 tcaagatgtt ggtgtctttt taactggtgt aaaaattggg gaggttttgt aagatgggat
    45181 taaaatttcc aaataattat gacattacag aagcattaga tgaaacttgt ttaggagccg
    45241 tacgctttgg cgcattagaa gagtctgatc gtgtatttga taatgaaaca ggcgattata
    45301 cgggagaaat tcgatcacag cgagcacaat tagtttttgg aaatccagat gaaccaaaga
    45361 ttgcacgacg agttaaattt ccagcagatg tagatttgac tggttttaaa cgacgtgatc
    45421 ctgtgaaatt aattgatcca gaatatcatg tggtatatat tccagcacaa gatggcaatc
    45481 gtgaatattc agatttagtg atttatgcga aaggattaga gaaagtagaa gctccaacaa
    45541 ataatcctaa tatgaaacaa tcacaagaaa aaggtttaga tcaaaaacaa ccaagtgttg
    45601 attctaagga aaaagagaaa aaataaggtt tttttgaaag aataggaagg agtcttccta
    45661 ttctttttat ctaagataga aggaagggga gattttgaat tcagataaaa ccaatcaaat
    45721 actttgagag attgtgcttg ttatcaaaat atccaacaat tgattgagta ttttggagac
    45781 aatccaacga tttttgtaca aacaaatgca tatatttgtg cggttattgg gcagtgtatg
    45841 tttttacgtg atcttgttcg tttttcatta ccgtaccagt ggaaacaaga tcatcaggaa
    45901 gtgatttgga ttcgtatagt acgaatatgt aatatgtgtg cacaccctta taaaaatcga
    45961 ttaaatcttt ttcgattatg tttttttact aaatgtgata ttcctgtatt agttgctttt
    46021 tgtcaaaagt ttttagcaca ggaaaagtaa aaacagaaag gaggaatgtg acaattgaaa
    46081 gctcattttt tcaagtatcg tggtcggcga attcgctatt tcaatcgtta tttatggttt
    46141 tgctattatg gtttcttttt gtttccattt ttgattctgt taggttggtt tagttggaaa
    46201 gtattttatc cacgtttaag tacgttttcg aattggcaaa tgtatcttat tcctggaata
    46261 agtattgtgt tgtatttgtt gctggttagt gggttaattt tagggttgat gcattggtcg
    46321 cgactaaaag aaggatattt tgcctctgtt tattggcgtc agttacttgt tcgaatgtta
    46381 attgacaatc ggtttgttta tacaaagaaa caagttagtg agaaacaaac aagggaaaaa
    46441 atgagattac caaaagttta tttttatcaa aagaaacaag aattagtggt ttcttttcct
    46501 ttagatggtg ggcgttttca cgaacgattt ttaaaaatgg gtcatttgtt atctgaagta
    46561 tttttgcgtg atttaattcg tgaagaacga gaaaaagccc gaatcaatta tgtattcctt
    46621 tcagattctg gtcggattcc tattgatcaa tgtatagcag aaaatggacg tattcattta
    46681 atgaaaactt tggattgggt atatgatcaa tcaccaaata tgttgattgc tggtgcaatc
    46741 ggtggtggga aaacctattt attgtattct ttaattcaag cttgtttaag tgttgggaca
    46801 gtagatattt gcgatggaaa agcggcagat ttagcagcat taggtgacgt cgatgtattc
    46861 aaaggacatg tgttttacaa aataaatgaa gaaatgatta tttgtttacg aaatgcatta
    46921 aaagaaatga atcaacggta tgcctatatg aaaaccatga aagatcctaa atatgaacca
    46981 gggaaaaatt atgcttatta tgggttacca ccgcatttta tcttttttga tgaatgggca
    47041 gctttttatg gttcgttgga tatggaagcg agaaatagag tcgataaatt gattcagcca
    47101 ttagtattaa agggtcgtca agcagggatg tacattattt tagcaatgca acgaccagat
    47161 gcagaatatt ttccaagtgg tgttcgggat aatttaacat tccgtatttc tgttggtcga
    47221 ttgtctccca ttggttattt aatgactttt ggagaagatt ttaaaaataa gccattttac
    47281 aacaaagatc aacctggtcg tggatatgct tttccaggat ttgatgtacc tgtagagttt
    47341 tttgcgccat ttgtttacaa agattatcac tttatcaaag aatttgagaa atttactgaa
    47401 atgattgtct atgattttac agtaaaagag gatagtcaag atcaaacgat gggagatgat
    47461 aatcagttgt tacaagaaca actagagcgc caaatgtatt tagcaaaaga tccaaaagga
    47521 acaagttttt ctgatgcgca tattttgtaa tcaactaagg aggtgaagtt aaatggcaga
    47581 gagttgttat tatagagtag ctacagcaat acgaatgatt aatccttctc tttcttccag
    47641 aacgttttat gattggttga atcgtattga acaagtaact gattaccgct ttttgcgcaa
    47701 agaacgtgtt tttacaggaa aagttattaa tcaagtattg ctaacgaaaa aagatataga
    47761 acgattgact cgattgtatc attatcgagt agatttagaa gaggatttaa ctttgtcaat
    47821 ttatcgcgtt ttttctcctg aaaaatatag tgaaataaca aaattagatc atttaatttt
    47881 gtagttatta tctatcggga gggctctaga cgtagtctgg tagccgcact ctgcctggcg
    47941 gtgcgcatta aggctgcgaa gcatgggcct ataatgcgca ctcgctagca gcgtgtgcag
    48001 ctcacaaaga ggtcgtgcgc ttgcgcacgg cctctttgtg taaagccccc cgatatataa
    48061 tatggggggc agaaataaca taacacatag aaaaaagttt tataaaccct tttgtatcaa
    48121 gtgattatct aaggtcagca gttgtactac ttttcccaaa aaacgagggg gactagttga
    48181 tatatcggtg tttctaaagg gttaaaaaaa atcgattttg ttattttata aaaggagcga
    48241 gaaaatgaca ccgattgagc taaaaagcta cagaaagaag ttaagtgcaa ttcataatat
    48301 aagtggagat aaaaagccgc tatcacaagc aagatttgcg caattgatgg gctgctcaaa
    48361 agattacatt agaaagatgg aacaagggaa aagaaaaatc ccagaggatt ttgaacaacg
    48421 aatcaaggaa cgctttcgat tgtatatgaa aagcggaata gatcttcgag caatgattga
    48481 ttatttgcgt ctttcctttt ttgggacaga ctacaaaaca gtgattcaac gtgtattacg
    48541 aatggatctg acagaatttg aaacacgtcc aacgggcttg tatctttttg actgtctttc
    48601 tgttcgtggg aatatctggg tgttctggca ttcaaaacga actgtaacag aaaatgtact
    48661 tgtgcaattt tcaggacaag gttgccggga atatgaggaa gtcatgcgtg aacaacaaac
    48721 agattggcga acatggctat attccatttg gaaaaatcaa ggaaagttgg aagctggtta
    48781 tacacgtgtg caatgtagcc gattcgatat tgcgttagat gaactttggg gattggaaac
    48841 ggaagaacat ttcgatctct ttgaattact agaaaaacaa aaagcaggtt tattagaaat
    48901 ggactttaag agattccaga atattggcgg ttgtttttta gatgatggct attttcgaag
    48961 tgaaggatta tctttgtatt ttggatcgcg aaagagtcct ctctttttta atttttatga
    49021 gaaacgtttt gaaattgcga accgagaaaa aatttcagaa ttagaagcat taacgaaata
    49081 tggtatttat aatcgatatg agttacggtt agccaatgag aaagcaacac aagcagtaga
    49141 agcatttatt ttaggtgatt caccgaaacg tttaggagag attggcgttg gtttaattaa
    49201 tgcaaaactt attgtttggg atagactgga aagtgatgca cggattgttg ataaacgatg
    49261 ggcaaaatta tttcgttcga tggaagaatt ggattttaca gtaaagccag aaaaattctc
    49321 attagatcgt tcagaacgct ggtttttgaa acaagtagct ccgacattaa agttgttaca
    49381 agaagcagat cgtattttag gaagagactt tgtacaagaa gggattgata atgccgaact
    49441 aaatgacgag caacaaaact atctagaatg gatgggaacg tcaggaggga aaattgcatg
    49501 aatgcatata cgacaacaga atggctgcgc ctgttggatt taaaggctgc aatcgaagca
    49561 ttaaatgaaa agatggttga tttgtcttat tttcgttttc gagttcctta tattgaacaa
    49621 gcggtaaaag ctggacgtta tcaggaaaaa gagaactggc aagaaattgc acgcttatta
    49681 gaagttcgta agggatacga acaagaactc gaagagttgg aatttagccg aaggaaagga
    49741 aggctagaat tcattcgctt ttatcgattt tcattgccaa tacctgcgat tttagcggtt
    49801 aaaaaaggct gcgataaaat gaagatatat gaaaactgtg tggcagcact tagcagcgaa
    49861 aaacctctta tggaagaaat ttcattggtg actgtcactt gggaaatgag tcgccagcca
    49921 acagaagaac agacatatct ttctttagaa gagattgaga tagaattaga ggaaattggt
    49981 cgctatgcca cttgttctac ctattgtgga tcggtcatta gtattgctgg tgtgattgtc
    50041 taaatgaaaa aaattatgat ttatgttggt gcgtattggt cacgtgatcc aacagtatta
    50101 gaaaatccag aggcggtaca ctattgcttg cgccaattat tctatctgta taaagaacga
    50161 ttagaatcgt tgattcgtca gttaccatat actgacagac gtttagatga acttcttcta
    50221 aggtatccag caatgtataa acgacgaaaa aatagattgt taccagaaga gtatcccatt
    50281 gaaaaacatg aacttgaagg gcgatttgtg gcttatttct atgatgatgt tcgtatgcgc
    50341 ttagtagaac aacgaatgga aatagaaaat gatcgctact attttatcaa ttattgtaag
    50401 aagcgtaagt atcaagtaac tgatgatttt tatgattgta ttttacaaga tggggaagtg
    50461 attctatcca aaattgctcc aagttttcgt gaacttgtgc cgattgattt tttgaaaaaa
    50521 tgtcatttgc ggattcttcc gtaaaaaaga gctataaaag gaaagaaaag tagaagccaa
    50581 atcggtttct gcttttttat tttttttagg aaggagaaga tggtatgtca ctggaatttt
    50641 taggagagcc aattgaaaag gaagagttcg tttcgcatta tatggatttg tttattcagg
    50701 tgataaaaaa ctttgtgcga ttgatgaatt ttatccacgc gaacaagact atctagccgc
    50761 tgaacgaata aaaatcagtt tattatggga aaaattcaca gatgaaaata accgaccgcc
    50821 agattatcgc tatttatcag attgtttaac gaataatgtg ctttctaaag aatacctatt
    50881 tcacaaacgt gagaaaaatc aaatgtcggt tgaacatttt tgtgattgtt atattgcatt
    50941 attgcgtagt caacagttat taacagtaga acgatatggt gcagagtttg gttatgtctt
    51001 gcaagctgag cgtcatagag ctacaagatg ctatgaaaaa gaagatcaag tgattgatgg
    51061 ctatgaagaa ttatgtattc gaaacaatcg ctatttgcaa caacgtttat atgaacaatt
    51121 gatgatggat ttttcaaatc tctatagagg gtatgaatgt tcgatgattc aagaaaggta
    51181 gaagaaaagg gggaattttt atgtggcgat tattattttt ggtggtatgt ggtatggcat
    51241 tgttctatgt gtatcgtgtc tatctctatc cacgaatgga acgatggaca agttggtata
    51301 gagatccttt aaaacaacga aaaggattga agcggtatcg ttatgaatta cttgttgaat
    51361 tttcggatgg gcgacaagca cagtattatt tttttgcaaa ctatccaaaa tacaacacca
    51421 gtgaactatt gattcaatta ttcaaaaata atccatatgt tgggttagaa gaaaacggac
    51481 gggagttctt ttatcgttca gataatatta gtgcggcgtc tatgaacaaa acacgaattg
    51541 cataaaaaat tggaggaata atcatgaaaa aaacaacatt agcagtcgta acaacactag
    51601 gaatttcatt attttcgttt caattaggga gttcattggt ttatgcagat gaaactgtag
    51661 aaacacctaa gtcagaaatt gtagaaacat tgccagggga aggattacca gatgttgaga
    51721 cagagctaaa tggaggaaca acggaaaaac cagcagaacc tgaacaattg cagtcagaga
    51781 aacctgaaaa agagccagtg acaccagaac cagagtttcc tgaatcaact ttaccgactg
    51841 attcgatcga agaagaaggt gtgcatagtt caacaacaac ggattcaagt atagtcacaa
    51901 ctccggaaca atcaggaaca accagttctt ctgaaaagaa tactgattcg tcaagtacgg
    51961 aacagccaac gatgtcgtct accagtgaag aacaaaaaga agaaccgaaa caacctgttg
    52021 aaaaatcaga agcaattcca aaagaaaata aacctattgt tccagcaaaa gaagtcacag
    52081 tatcggtaac cccaagcggt gaaattacga cgaatacttc tcaaggaatg agtgtaccga
    52141 ttgtcactag taatgtagag gaattgaccc atattccaac accaaccacc ccattaaaag
    52201 tagcaggtga tcaaacaatt gttggtgtaa aagatggtat tccattaatc caagatagtg
    52261 aagggaattt ggtaaaggat ttgtcgattc ctgtaaagaa acttccaagt ggcaatattg
    52321 aaatcaaaac agcagatgga aaaacaaaag tcttaccaaa gactggtgaa gaaatacatg
    52381 ttgcactttc tgttctagga ggagtgttga caagtattgc tggatttgtt ggatataaaa
    52441 gaaagagaaa aggaatagaa aatgagggta attgaatgga ctatttttca gaaaaacaag
    52501 cttatcgttg tcaatcgtac gtactagtaa aaacatacta gaaggagtag cttatgaaaa
    52561 aacgacaact acggcggaaa gaaaaagttt atacagagaa agtaccgaag caaaagaaaa
    52621 tccattcaaa aaaagcagtg aaatggattt ggtgtttggt tttatttctt tgtttttcag
    52681 ggggcttggc attttttcaa tccatgaaaa cgaaggttca agtgtcgttt ttgaaagatg
    52741 aaatccaaca attacaaaag aaagaagtac aaagtcggtc agaattaacg tacacacctg
    52801 aaattgaatc ctttatgaat cgttttgttg ctttgtatat gaatacattc gataatcatg
    52861 aacaagaaca acaacgtcaa gaaacattaa aaaaagagtt ttatgcacaa aactttattc
    52921 aagaaccagg aagtgtttca ggtgttcgaa aattaactgc tgcttcgttt attggattaa
    52981 aagaaattga aaccattcca actgctagtt ataaagtaac ttatgatatt cgctcgatga
    53041 atccagagag taagaaagaa acaagtgtga caatcacaca agtactcaat cttccctttt
    53101 ctatttcaaa caagggctgt cgtattattg cttatcctta ttttacggca ctaccaaaga
    53161 atacagaaaa acaacgaatg attacttatg atgacacatt atacgaaacg gttgatgcgt
    53221 cggaagcgaa agatgttgaa ggatttgtgg aagatttctt agataagtat gcgaaaaaca
    53281 atgcaaaaga tatgtcatac atgatgaaag aacctgaagg actcaatcaa acagctaaag
    53341 ttgatcaagt agagatgaaa gtattgcgtt ataaagaaac gaaaaaacct tttattgtaa
    53401 aagcaacggt cgtctttcga gatggtgata cgtcactttt acaaaaagaa caaatgacga
    53461 ttgtcattac gaaaaaaaca aatcagtatt atgttgaaaa attaacacat aattggttgg
    53521 ataggaaagg agaagaacgg aaatgacact gaagggaatt gtagatttta tattaacgca
    53581 aggtggctat tttttaataa tggtggttgt ttatctggga ttgcgaaatt ttatgaaatc
    53641 aaaagtagga aatgcattaa tatctatcgc agcaggtgcc gcagtttatt tcttcttaaa
    53701 tgatccaaca cgtgtatttg atgcgtttgg taaaatcatt gaaaaattat ttatggatta
    53761 ggaggatagt gaagtggatt gggaacctta tgattattcg attgtttatg cggaacctta
    53821 tcgcgtacaa cagattacaa gcaattggcg tcttccattt ccagttgcat tagtcaatgc
    53881 agcaactttt ttgttggtcg taatctttga atatttattt ttacgttcat ttattggttg
    53941 ggtcatttct ttttttccac cagcaggagt tgttttttat ataggactcc cctatttatg
    54001 tgtgttagca ctggcaaaac taaaacctga tggaaaaaaa gtgcattttt atttatggga
    54061 ttggttttgt tatatgattc gtatgatgaa tggtgattgt gtgtattata actgggacaa
    54121 ggtatcaaac aatgcattgg aagaattact ttttgtgaat aagtatgttt atttagagga
    54181 ttagaaaaag ggacaatcaa ctggttgttc cttttttatt gggaggtgaa attcattggt
    54241 gcttgtaaaa gaaccagtaa aagcattcaa gaaaaattgt ttgttaaatg gagaggattg
    54301 tatctgggcc tactatcatg tttttccacg aacaatttca aaaaacacac caaaaaagac
    54361 acaggaaata aaagaaatga tggctcgttt actgttgctt ttagcagatt atgaagatgt
    54421 ggagttggtg atgtatccac gaacaatgaa tttacggacg aagtttgaca cattaggaaa
    54481 gggattttct cccgatagtc aagcaattgg tgcgtattat gcaaaagaaa cagtgacatt
    54541 gttggaacga gaaggtcaag tctatcgtcc ttcatttatt ttaggaatca aagtcaaaga
    54601 aaaagcaacg gtggagagtt ttcatgatgt aataaatcta atctggttag atttagcagg
    54661 aagtttagca cgcttatttg gattagaagt agatgatttg gaaactttgt tttctgaaag
    54721 tgatccttat gtaaaagaag tgacacaatt actttatagc ttttctattc gtcccttagt
    54781 aaaaaaagag ctgttgtatc tcaatcgtct gcaatatatt cgaggaatgg ctcacaaagt
    54841 agaagaacaa aataattggg aagtactgaa agacaatcaa ggaacgtatg tacgtatacc
    54901 gaaggaacat aaaggccttc ttcaattaga agatgagtta gggagtagtt atttagcatt
    54961 gttgcctatt ggggaaacac ctgaaaatat gagaaattgt gatctatttc aatttgctca
    55021 ggatctttct ttcccagcag aattgcgaat gaaaattcac tatccacgct tgaaaggaca
    55081 gggaggtatt ggtttaaaac tgaattggct atcggaacgg ttcaaaacag agcataagga
    55141 attggttcaa aatgatgaag aacctagtga acgcttatta actgttcgag gattagtaaa
    55201 acatttaaag caacgagtag ataatgggca acctgtcgtc gattggatcg catgttttat
    55261 tgtatacggt caaacggttg aagaagttcg tcaaaatagt gcaacggtta ttcaacaact
    55321 tcatacgatt atccatatcc accgtgcaaa aaatgatcaa cgagaattgt tctataaatg
    55381 tttattaggg caaccattgg gacggcagtt acattggaag caccgaacaa ctgtagaagc
    55441 agttggcgaa tggttgtttt cagcagtatc agaattaggt atggaatccg gctggtatat
    55501 tggtcggcaa gatacattag gggatggtgg ttctcgagga gaaaaaacac cattagaaga
    55561 attaatttat gcgtcaaatc gttttgtctt tttgaatctt ctagccattg cggaaggaat
    55621 caaaggtgcg ttgtttgatg cgcctcatgt agcagtaact ggaaaaaccg gtaaagggaa
    55681 gaccttttta gttggcttgc tctttttgta tagttcgttt atgaatgtac aaagtttatt
    55741 tgtggatccc aaaggagaaa agcgcaaatg gtttacgaaa ctcattcaag acccgtatta
    55801 tcagaaacat taccctttgt ttgtagaaca tttgcaaaaa atgagttatg tcacgttaga
    55861 tgctacaaat ccccgtaatt atggtgtatt agatccaatt gtttgtttat cccgagtaga
    55921 tgcgaaacaa gtagcccagg atatgattga tgagttaagt ccgttaggta ccaatcacct
    55981 tttaaaaggg gcggtattaa agggaatcca agaagtttta gttcaaaaag aagccggaca
    56041 acaagttggc ttgatgcatg tggtcgacta tttagaacaa atggaacaaa aagaggttcg
    56101 agaatatggt gagtttttac gcttgacggt agaagattcg attttacgtt taggattttc
    56161 ttatggagaa aacccgggat tagactttaa tgccaaaaca acgattttag agatccaaga
    56221 tttgaaatta ccaaatgaca atgtccgacc agaactatat acagatgcgg atcgaaagtc
    56281 tttgtgtttg atgattagtt taggtcgttt ttgtgaaatg tttggaaaac gagatagtag
    56341 taagaaaaca gcgatttatt ttacagaagc atgggtattt aataattcga acgcaggacg
    56401 tagtattatt gcagcaatgg cacgtgtggg gcgttcccag atgaatcaat tagtgttaga
    56461 tacacaattt attggtgact taggttcaga taaagaaaaa gggaattttg gtgtcgtctt
    56521 tgcttttgat gaagacagtg agcgagaaaa gattttgaat catttacgtt tggaagtaaa
    56581 tgaagcgaac ttagctgaaa tgagccacat gattaaagga cagtgttgga tgttagatcc
    56641 ctatggacgt gtaggaaaac tcaatgtaca cagtttgttt gaagaaatga ccgctgcatt
    56701 acaaacaacg gaaaaaacaa gtcactctca agtagaagaa caggatacgt taatcatgca
    56761 atagaaatga ggtgaaacaa tggcttatat aaagcataag gaaaagaaat ggtgcgtttt
    56821 gtttttttta acgattggat tcggactgct ttttgttggt ggattggtgt atgcggcaga
    56881 aaagcaggtg gatcaatcga tctatgagat tgggaaattt catattgata ccttttcttc
    56941 ttatttatct gatagtgaat tttcattagg caaaatgtta tttggggcaa atggcacaga
    57001 ttttctaaaa atgatgacga atatgttctt tagtttaagt aaattgattt ggcaaggcct
    57061 tgattttgtc attgagaagc tctatgaagg agctgcaatg aacgagttaa ttcaccagtt
    57121 tttcactttt tcggatacta tttattcaaa aatatacgat cctattggtg cggggattgt
    57181 cgtcttgtat gtgttatatc tatttactct tcgtatattt agagggaaac attacgcaaa
    57241 aatggtgttt attcgatttc tcttcgttgt cattttttca atggtttggt ttggctatgg
    57301 tagtaacgta cctagtaaag gagaagcttt taccaaaggg ttaaatgatt tgtccgtgga
    57361 ggtagaaggc tttatttttt ctgctacaaa tagtctagat gaattggcga caaaagatgt
    57421 caatggtgtt ttagtgccaa cgacacaaaa ggaagccatt caaaaagtgc gccaacttta
    57481 ttataaagcg gctgttgttg atccgtatat attgttaaat tatgggacaa caaatttaga
    57541 agaattgtat caagcagaga ttgaaccaca agaatttcta gccaaggaag cgtcaagtga
    57601 agaattatct gatattgaga caaaagtgac cactgctgca ggagaagata gagggaaaaa
    57661 gaaggcttat cgtgtctata ttcaaccaac taaagctgtt tataaagcag tcgttggttc
    57721 tatggtgcca ttgcttaatc taagtattgg attaccactt gtagtgattg gcatgattcg
    57781 ttttatcttt caaatgttgg tgttgtgttt attacttgtg attccttttt cattactcgc
    57841 ttcttttgtt ccagtatttg attatatgct catgaatacc ttaaagtcct ttttgggctt
    57901 gatgtttcaa aaatcttttt acagtgtgat tattttggtg gcatttttga tctataacat
    57961 agtagacgat ttaattccaa tgaatactgt ttttggtttt ttaggaaata tgtttgtcaa
    58021 agcactccta tcaattttac tcattgtaaa acggaaagat ttattaaaga aactagggtt
    58081 aggagctgca gatcaaacta taaacaacac gaaaaacata gcaagtcatt ctttgtctca
    58141 aatgaaacaa ctgcctggtc aactatcaac tgctggacaa aatttggcaa tcaaaggtgc
    58201 aggattagca gggaatgtgt atcgagcaac gaatccactc gcttctgcag cgatacatgg
    58261 atttcaaaag tttcaacaaa aacgtacacc acaagaatcg gtaaaaggga ggcaagtggt
    58321 taatcccttt gaactaggtg ggcgttcaaa tcaagccttg ccttatagtg gtcgtcatgt
    58381 tcgttatcat ggggtagagc ctgaaatgtc ttctaccaaa tcgaaaacag agtggaattc
    58441 tggtctttca aatggtttga ttccaaattc gtccatgaat tcagtaagac caaaacaaca
    58501 ggtacaatca ttggcacaat tgagtaagca acaagggaat aatcaaagaa aaccattgtt
    58561 aaataaaggt atcgcttttg ttggtcaatc gattccgttg ccttctggaa aagtacccgt
    58621 gccacaatta acagctgctg gttctctttc acaacagatt cgccaagtga aaaatcaggc
    58681 gaaaaatggg agttatccag caatgcagca gttattgaac caatactctg ttcctaattc
    58741 gtcggtagcc actctatcag gaaatcgttc tgtgcaacaa ccggggcaac gttcgtctga
    58801 aagtaaaccg tcgatttccg caccaaaatc gttacaacct gcattttctt ctttagataa
    58861 gccaacagag caatcggaaa aaatagaaaa ggatcctaaa acactgccga ttttggacgc
    58921 aaaaccagga actgatttta ctttaccaaa aggacgaaca gtccaaaaac cattatcgaa
    58981 gaaaggatga ggaagaaatg aagaaagggt gtctaggttg tcttcttttc tttattcttc
    59041 ccttttttct attgccattc tttttttcag gagaactttc tgagcatgga ggagaagcta
    59101 caggtctagc tgtcgctttt aatggggaat ataccgaagg attaccgatt ttttcagaga
    59161 ttaaaggacg tggtccaatc acagatgaac atgcgcaagc agcagttggt gcagctgtaa
    59221 agtatcagtt attaccgagt gtgattcttt ctcaattagg ctatgaatca gcttatggac
    59281 agtcacaatc tggaagaaac gatacgaact tttttgggat tacctggttt cctggttgtc
    59341 cctacccaca aggttctgca cgtggaattg gtggttctga aggtggtttc tatatgaagt
    59401 ttccgaactt aaaagcttgt tatgactatt atggctttat ggtggcgagc caaagcaact
    59461 ttaatcaatg tgtgggcaat aaagatcctg gaagttgttt attgattcta ggtcgtggag
    59521 gctatgcggc agcaggtatt accgaaggga gtccgtatta tcgaggagca atgagtatca
    59581 taacgtccta taacttaacg gaatatgata cttttgcgat caagcattgg aatagcctac
    59641 caacaaaaaa aacttcgctt attgcaggaa aaagtaaagg caatgcgaag gttttggatc
    59701 ggatcattgg acgatccgta aataatgggg aatgttatgg tggtacggca tggtatgtat
    59761 ctcaattagg tggcccacag ttaatgggtt ctggacacat gtttgcgatg ttaatagggg
    59821 aagattataa ctggacaacc tatggttggc aagtaatcat gaacccaaaa ccaagtgatt
    59881 tacaagcagg agatgtggtg aattggcaag caggtggtgc attgtctcct ggaatctatg
    59941 gtcacaccgg aattataaca gatgtttcat atggcggaca acatttctct agtgtggaac
    60001 agaatgccga gcaaggacgg attatggctc ggtatcaacg cacgtacaat caaacaaaaa
    60061 ttcgtagtct ggttcgtaag gtgaaataag aaaggcagtg actagaaacg tgaaaaaagg
    60121 gataatttta gtatttagtt ggttatgttt gataggtctt actggttgtc attggttttc
    60181 ttctgaaaaa caaaaaacac aattgagaac gacagaagaa acaatcgaag cagtaaaaga
    60241 aacaagtgga actcttcaaa gtactgaaag taacagtcaa attggttcat tagaagacga
    60301 gacagcgcaa caaatgcaaa tagatgaaat gacaaaaaat ttcttaaaag attttgctag
    60361 aaaatggagt aatttcacag atgtttataa acgcaatcaa gctgtgaggg actatatgac
    60421 agatcgttgt attaaagaca atagtattga tgtagacccg catgtacaaa tgaaaacaac
    60481 tgggaaactt taccaggtga cacaagatat agagaatccg gatcaatatt tgttatttgg
    60541 agaagaaaca atgaataagg ttactcaatt tgtattactt caattgaaag tagatcaaga
    60601 agctcaaaag attgatgcga tcaagattta ttatgtacgg agtgcgtatt aaaataaaaa
    60661 atgaacactc atatttatta tacaccgaag aaatagaaaa aaacagactg tttttttaag
    60721 aaaaactatg tcattcttta cttgaaaaaa gttgttatag gacagaaagg ataaaacaaa
    60781 aacggaaaaa atatgtctta tgaataacta taagaactat tctatttttt aggagatgga
    60841 tacgagatga aaaaactaat tggctatagt gtgatgtgta ttggatttgt tggtgtggga
    60901 ttgtttgtat cgactgaatc tgcttctgcg gctgaatggt ataatcctat ctggtataat
    60961 ccgaacattg aatgtcaaaa aggctatccg tatggaccga caaatctgaa aaatggaaaa
    61021 tgtagagtaa attggaatgg cgttgtagat agtgtaatta ctggttcaat ggactctgct
    61081 ctacatggct ttacgggtca ctagaaggag gaagaaaatg tctgaagaga aaaaagaaat
    61141 cgttgaatca ttagtagctt taaaagattc tctttctaag attgaatatg ttgataggca
    61201 agaaattcaa aaactaattg atgatactat tattgaaatc caagatgcgc gttgtgaagg
    61261 tataaaaatt tctgtagctt tatctaaagt aatagaaaaa atgaaccgtt cattagcgtt
    61321 taatggattg aagctagata gacaaactag tctgatatgg gatcatttaa aagacttgta
    61381 tgacaagtct aaaagaagtg aacggactgc tgtatcaatc ttaaaaggcc tttggggaat
    61441 gaattcataa acaagatatt taaaaagtaa cttatttttt atggaggaga aattatgaaa
    61501 agaataatta aaatatttgg tgttttaggt gttttcttat taggtttaag tacttttgtt
    61561 agtactggaa caagtgtgta tgccacagaa aaagtgaata cagttgattt agaaataaag
    61621 aataaattag tagatgaatt aactttttat tttgatacag ttggtttttt agacgaacat
    61681 ggtgtatacc atataaagga ttttggtgct attcgtgaac gaatcagtca agataacgaa
    61741 caaggaagag cagcaagagt cttttatgaa catattattg ttcctagaat ggagaaagtt
    61801 gattggaaac gatatgctgg atgtgtagcc attaattctc ttcctggagg aggagtggct
    61861 tgggctatag gtacgcaggg agattttatt gaagcattaa aagcttttaa ttttgaaaaa
    61921 gctgcggatt tattattaaa aattgcagaa aaacaattag gaaaagctgc agctaaagag
    61981 ttagctaagg taaatattgt agcaggaatt gcagcagctg ctgctagctg tgcattagag
    62041 taaaagttta tgaaaagttt agaacaagag catatggctt ttaaacaagc aatgtttaaa
    62101 gaaaatatct atttaaacca taactatatt cgtgtttcta aggcatgttc accagtattg
    62161 aatatgcttg gaggtggaaa tggattatat catttactgt ttgtcgatgt ttgttggtta
    62221 atttttttac cagatgaact agttatagtc aatgaaaaaa taacaagtaa aaatgaagtg
    62281 tttaattatt ctttaacaag aattaattac aaagagatta ccaagttttc actagaaaaa
    62341 gttccttttt ggggagaatt ttgtttaaaa attaaatgta actggaaaag aatgtatttc
    62401 tatattgatg gtgatgatgc tcttacattc ggtaaaacta ctttttctag ttttaatttt
    62461 cagtttctat taaaaaataa tttttatggt ttattgaaat aaggttgcga aggaagatgt
    62521 agagttattt gcactgttgt gttggtatat ctcttaatgc tgtgtctttt tggggagatt
    62581 aattagtgga gtgattatat gagtatagat gattgtttag aagaacaaat aagattattt
    62641 ttaaagtttt taaaagttaa agttcaaaat aactacttca catgttatag ttatgcacac
    62701 cctgttttaa atagtcttcc ttttaattct ttagtgcaag gattgattac aaatattgtt
    62761 ttattagtct gtacaccaaa tgaaatattt gtaaaaaaga taggcagtgg tatttcttca
    62821 gtaagattaa aagagaaaga atatactcaa aagattattc atattcctaa gcctgaaatt
    62881 aagcgttttg agataaaaga ctattctgct ttagggctgt tctcaattgg ttactggtga
    62941 taaaaaataa gaatactaaa actatacgta gaatataagt aatcggcatc aatcctaatt
    63001 atgtgattga atgccgattt ttgttacgcg ctatttttaa ttatctgtaa gaagaataat
    63061 tttattttac tcatattcgt tttcactttg aagaagtaaa ttgcaatttc ttataagtta
    63121 agcagctatg caaaaggcta tttattctat tgtgaaatat aagatgtagt tgaaacagga
    63181 tatatagaat caaaatacga atcttatttt gatttttcta gttttttgaa aaaagcaccc
    63241 tttgatcgtt gtattagtgg aaaagagaaa aaggagcata cttatcatgt cacaaaacta
    63301 caactaaata tctaaacaac accaatttga tgcctattga aaaaaagtat tgcgaaatga
    63361 agccaagtct attagaaaat gaaataatag aataaaagaa aatgggaaac cgctgaatga
    63421 tgtaaatgaa ggtaagtatc cacgaactaa ttttgatgaa caagatatct attttttatt
    63481 tgtattggag atactagttt aatatcaaaa gttatcagca gtcataatta gttatccaat
    63541 gtaaaaagta caaacaatag ttgttatgca gaatagttta tgaaatatat tacataataa
    63601 gaaaacaagc ga
//
LOCUS       DAFELK010000010        61541 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFELK010000010
VERSION     DAFELK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.010"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(59..187)
                     /locus_tag="LP433_000825"
     CDS             complement(59..187)
                     /locus_tag="LP433_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL2005009.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="LP433_000826"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="LP433_000826"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL2005010.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="LP433_000827"
     CDS             complement(1674..2729)
                     /locus_tag="LP433_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL2005011.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="LP433_000828"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="LP433_000828"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBL2005012.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="LP433_000829"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="LP433_000829"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBL2005013.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="LP433_000830"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="LP433_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBL2005014.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="LP433_000831"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="LP433_000831"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBL2005015.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="LP433_000832"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="LP433_000832"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBL2005016.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="LP433_000833"
     CDS             10491..12050
                     /locus_tag="LP433_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBL2005017.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="LP433_000834"
     CDS             complement(12161..14092)
                     /locus_tag="LP433_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2005018.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAEEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="LP433_000835"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="LP433_000835"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBL2005019.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="LP433_000836"
     CDS             complement(15021..15773)
                     /locus_tag="LP433_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2005020.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="LP433_000837"
     CDS             complement(15932..16141)
                     /locus_tag="LP433_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005021.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="LP433_000838"
     CDS             complement(16152..17480)
                     /locus_tag="LP433_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005022.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="LP433_000839"
     CDS             17616..17771
                     /locus_tag="LP433_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005023.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /locus_tag="LP433_000840"
     CDS             complement(17845..18432)
                     /locus_tag="LP433_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBL2005024.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="LP433_000841"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="LP433_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBL2005025.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="LP433_000842"
     CDS             complement(20012..21301)
                     /locus_tag="LP433_000842"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBL2005026.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="LP433_000843"
     CDS             complement(21455..22387)
                     /locus_tag="LP433_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005027.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="LP433_000844"
     CDS             complement(22544..23203)
                     /locus_tag="LP433_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL2005028.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="LP433_000845"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="LP433_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBL2005029.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGASGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="LP433_000846"
     CDS             complement(24244..24534)
                     /locus_tag="LP433_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005030.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="LP433_000847"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="LP433_000847"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBL2005031.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="LP433_000848"
     CDS             complement(26821..28176)
                     /locus_tag="LP433_000848"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBL2005032.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="LP433_000849"
     CDS             complement(28200..29369)
                     /locus_tag="LP433_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005033.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="LP433_000850"
     CDS             complement(29366..30253)
                     /locus_tag="LP433_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBL2005034.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="LP433_000851"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="LP433_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBL2005035.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="LP433_000852"
     CDS             34320..34841
                     /locus_tag="LP433_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL2005036.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="LP433_000853"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="LP433_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="LP433_000854"
     CDS             complement(36284..36940)
                     /locus_tag="LP433_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005037.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="LP433_000855"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="LP433_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBL2005038.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="LP433_000856"
     CDS             complement(38477..39475)
                     /locus_tag="LP433_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBL2005039.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="LP433_000857"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="LP433_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBL2005040.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="LP433_000858"
     CDS             complement(40491..41222)
                     /locus_tag="LP433_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBL2005041.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="LP433_000859"
     CDS             complement(41226..42491)
                     /locus_tag="LP433_000859"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBL2005042.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="LP433_000860"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="LP433_000860"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBL2005043.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="LP433_000861"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="LP433_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBL2005044.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="LP433_000862"
     CDS             47833..49335
                     /locus_tag="LP433_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBL2005045.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="LP433_000863"
     CDS             49337..50074
                     /locus_tag="LP433_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2005046.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="LP433_000864"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="LP433_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBL2005047.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="LP433_000865"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="LP433_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBL2005048.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="LP433_000866"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="LP433_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBL2005049.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="LP433_000867"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="LP433_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBL2005050.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="LP433_000868"
     CDS             complement(55574..56740)
                     /locus_tag="LP433_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBL2005051.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGNRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="LP433_000869"
     CDS             complement(56756..56983)
                     /locus_tag="LP433_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBL2005052.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57370..57626)
                     /locus_tag="LP433_000870"
                     /pseudo
     CDS             complement(57370..57626)
                     /locus_tag="LP433_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(57969..58992)
                     /locus_tag="LP433_000871"
                     /pseudo
     CDS             complement(57969..58992)
                     /locus_tag="LP433_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(59476..59637)
                     /locus_tag="LP433_000872"
     CDS             complement(59476..59637)
                     /locus_tag="LP433_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005053.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="LP433_000873"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="LP433_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61417
                     /locus_tag="LP433_000874"
     CDS             60827..61417
                     /locus_tag="LP433_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBL2005054.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
BASE COUNT        17077 a        13213 c        10649 g        20602 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttcttcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagcc cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attgggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atttccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt catagatgga a
//
LOCUS       DAFELK010000011        59631 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFELK010000011
VERSION     DAFELK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.011"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(185..310)
                     /locus_tag="LP433_000875"
     CDS             complement(185..310)
                     /locus_tag="LP433_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2005055.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(444..1337)
                     /locus_tag="LP433_000876"
     CDS             complement(444..1337)
                     /locus_tag="LP433_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBL2005056.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(1519..2445)
                     /locus_tag="LP433_000877"
     CDS             complement(1519..2445)
                     /locus_tag="LP433_000877"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBL2005057.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(2530..3291)
                     /gene="pflA"
                     /locus_tag="LP433_000878"
     CDS             complement(2530..3291)
                     /gene="pflA"
                     /locus_tag="LP433_000878"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBL2005058.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(3535..5766)
                     /gene="pflB"
                     /locus_tag="LP433_000879"
     CDS             complement(3535..5766)
                     /gene="pflB"
                     /locus_tag="LP433_000879"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBL2005059.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6043..8493)
                     /gene="parC"
                     /locus_tag="LP433_000880"
     CDS             complement(6043..8493)
                     /gene="parC"
                     /locus_tag="LP433_000880"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBL2005060.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(8505..10550)
                     /gene="parE"
                     /locus_tag="LP433_000881"
     CDS             complement(8505..10550)
                     /gene="parE"
                     /locus_tag="LP433_000881"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBL2005061.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(10716..11150)
                     /locus_tag="LP433_000882"
     CDS             complement(10716..11150)
                     /locus_tag="LP433_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBL2005062.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11277..11915
                     /gene="plsY"
                     /locus_tag="LP433_000883"
     CDS             11277..11915
                     /gene="plsY"
                     /locus_tag="LP433_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBL2005063.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12047..12922)
                     /locus_tag="LP433_000884"
     CDS             complement(12047..12922)
                     /locus_tag="LP433_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL2005064.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13004..13795)
                     /gene="codY"
                     /locus_tag="LP433_000885"
     CDS             complement(13004..13795)
                     /gene="codY"
                     /locus_tag="LP433_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBL2005065.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(13813..15213)
                     /gene="hslU"
                     /locus_tag="LP433_000886"
     CDS             complement(13813..15213)
                     /gene="hslU"
                     /locus_tag="LP433_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBL2005066.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15227..15775)
                     /gene="hslV"
                     /locus_tag="LP433_000887"
     CDS             complement(15227..15775)
                     /gene="hslV"
                     /locus_tag="LP433_000887"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBL2005067.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(15812..16717)
                     /gene="xerC"
                     /locus_tag="LP433_000888"
     CDS             complement(15812..16717)
                     /gene="xerC"
                     /locus_tag="LP433_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBL2005068.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(16915..18291)
                     /gene="trmFO"
                     /locus_tag="LP433_000889"
     CDS             complement(16915..18291)
                     /gene="trmFO"
                     /locus_tag="LP433_000889"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBL2005069.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18260..20338)
                     /gene="topA"
                     /locus_tag="LP433_000890"
     CDS             complement(18260..20338)
                     /gene="topA"
                     /locus_tag="LP433_000890"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBL2005070.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHGHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(20460..21317)
                     /gene="dprA"
                     /locus_tag="LP433_000891"
     CDS             complement(20460..21317)
                     /gene="dprA"
                     /locus_tag="LP433_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBL2005071.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21373..22140)
                     /locus_tag="LP433_000892"
     CDS             complement(21373..22140)
                     /locus_tag="LP433_000892"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBL2005072.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22133..22993)
                     /gene="ylqF"
                     /locus_tag="LP433_000893"
     CDS             complement(22133..22993)
                     /gene="ylqF"
                     /locus_tag="LP433_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBL2005073.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            complement(23087..24046)
                     /locus_tag="LP433_000894"
     CDS             complement(23087..24046)
                     /locus_tag="LP433_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2005074.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
     gene            24318..24716
                     /locus_tag="LP433_000895"
     CDS             24318..24716
                     /locus_tag="LP433_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2005075.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24995..25495
                     /locus_tag="LP433_000896"
     CDS             24995..25495
                     /locus_tag="LP433_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL2005076.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(25578..26129)
                     /gene="lepB"
                     /locus_tag="LP433_000897"
     CDS             complement(25578..26129)
                     /gene="lepB"
                     /locus_tag="LP433_000897"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL2005077.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(26281..26508)
                     /locus_tag="LP433_000898"
     CDS             complement(26281..26508)
                     /locus_tag="LP433_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBL2005078.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26505..27023)
                     /gene="msrA"
                     /locus_tag="LP433_000899"
     CDS             complement(26505..27023)
                     /gene="msrA"
                     /locus_tag="LP433_000899"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2005079.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(27043..27756)
                     /locus_tag="LP433_000900"
     CDS             complement(27043..27756)
                     /locus_tag="LP433_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBL2005080.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27759..28655)
                     /locus_tag="LP433_000901"
     CDS             complement(27759..28655)
                     /locus_tag="LP433_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL2005081.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28813..29655)
                     /locus_tag="LP433_000902"
     CDS             complement(28813..29655)
                     /locus_tag="LP433_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2005082.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29787..30440
                     /locus_tag="LP433_000903"
     CDS             29787..30440
                     /locus_tag="LP433_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBL2005083.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30503..31030)
                     /locus_tag="LP433_000904"
     CDS             complement(30503..31030)
                     /locus_tag="LP433_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2005084.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(31050..31997)
                     /locus_tag="LP433_000905"
     CDS             complement(31050..31997)
                     /locus_tag="LP433_000905"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBL2005085.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(32009..33895)
                     /locus_tag="LP433_000906"
     CDS             complement(32009..33895)
                     /locus_tag="LP433_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2005086.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(34055..36133)
                     /locus_tag="LP433_000907"
     CDS             complement(34055..36133)
                     /locus_tag="LP433_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBL2005087.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(36146..36421)
                     /locus_tag="LP433_000908"
     CDS             complement(36146..36421)
                     /locus_tag="LP433_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005088.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(36783..37238)
                     /locus_tag="LP433_000909"
     CDS             complement(36783..37238)
                     /locus_tag="LP433_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005089.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(37392..38600)
                     /locus_tag="LP433_000910"
     CDS             complement(37392..38600)
                     /locus_tag="LP433_000910"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBL2005090.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(38712..39044)
                     /locus_tag="LP433_000911"
     CDS             complement(38712..39044)
                     /locus_tag="LP433_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL2005091.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            39192..40067
                     /locus_tag="LP433_000912"
     CDS             39192..40067
                     /locus_tag="LP433_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2005092.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(40149..40730)
                     /locus_tag="LP433_000913"
     CDS             complement(40149..40730)
                     /locus_tag="LP433_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBL2005093.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(40736..41995)
                     /locus_tag="LP433_000914"
     CDS             complement(40736..41995)
                     /locus_tag="LP433_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL2005094.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(41997..43043)
                     /locus_tag="LP433_000915"
     CDS             complement(41997..43043)
                     /locus_tag="LP433_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005095.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(43278..43553)
                     /locus_tag="LP433_000916"
     CDS             complement(43278..43553)
                     /locus_tag="LP433_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBL2005096.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(43796..45106)
                     /gene="der"
                     /locus_tag="LP433_000917"
     CDS             complement(43796..45106)
                     /gene="der"
                     /locus_tag="LP433_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBL2005097.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(45288..46517)
                     /gene="rpsA"
                     /locus_tag="LP433_000918"
     CDS             complement(45288..46517)
                     /gene="rpsA"
                     /locus_tag="LP433_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBL2005098.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(46652..47332)
                     /locus_tag="LP433_000919"
     CDS             complement(46652..47332)
                     /locus_tag="LP433_000919"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBL2005099.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(47381..48016)
                     /locus_tag="LP433_000920"
     CDS             complement(47381..48016)
                     /locus_tag="LP433_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2005100.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(48082..49485)
                     /locus_tag="LP433_000921"
     CDS             complement(48082..49485)
                     /locus_tag="LP433_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBL2005101.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(49472..50503)
                     /locus_tag="LP433_000922"
     CDS             complement(49472..50503)
                     /locus_tag="LP433_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005102.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            50534..50755
                     /locus_tag="LP433_000923"
     CDS             50534..50755
                     /locus_tag="LP433_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBL2005103.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(50920..51657)
                     /locus_tag="LP433_000924"
     CDS             complement(50920..51657)
                     /locus_tag="LP433_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBL2005104.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(51810..53150)
                     /locus_tag="LP433_000925"
     CDS             complement(51810..53150)
                     /locus_tag="LP433_000925"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBL2005105.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(53387..54910)
                     /locus_tag="LP433_000926"
     CDS             complement(53387..54910)
                     /locus_tag="LP433_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBL2005106.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(55289..55900)
                     /locus_tag="LP433_000927"
     CDS             complement(55289..55900)
                     /locus_tag="LP433_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2005107.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(56023..56148)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(56230..56946)
                     /locus_tag="LP433_000928"
     CDS             complement(56230..56946)
                     /locus_tag="LP433_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL2005108.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(56952..57521)
                     /gene="scpB"
                     /locus_tag="LP433_000929"
     CDS             complement(56952..57521)
                     /gene="scpB"
                     /locus_tag="LP433_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBL2005109.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(57505..58302)
                     /locus_tag="LP433_000930"
     CDS             complement(57505..58302)
                     /locus_tag="LP433_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBL2005110.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(58272..58643)
                     /locus_tag="LP433_000931"
     CDS             complement(58272..58643)
                     /locus_tag="LP433_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL2005111.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(58662..59549)
                     /gene="xerD"
                     /locus_tag="LP433_000932"
     CDS             complement(58662..59549)
                     /gene="xerD"
                     /locus_tag="LP433_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBL2005112.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT        16317 a        12600 c        10189 g        20525 t
ORIGIN      
        1 tttatgtggc aaagaaaaaa caaacaaaat aaaaagcatt ttgaagcctg actattacga
       61 cttcataaat gcttttttag ttttaaacac ttcaatctaa aagaataacc caagattgga
      121 taaattatta atgactcgcc attcgtttct tagtgattct ggattatcaa atggacttcc
      181 taatctaatc agctagttct tcccataaaa tgccatactt gactgaatca taatattgat
      241 tatttaaaaa tctaactttt cttatcacta cttcctttgt cattccacat ttctcaccat
      301 ttttttgcat tcctttgttt ccagaccatg tagtgaatct aataggtggt agataggcaa
      361 aatactcaaa taattctttt aaccataaag gaagagaaag gctcctcctg caagagtcag
      421 tataattttt gcttactgct ctcttaggtt ttactcacta aaactgttcc atattctttg
      481 atataagaaa atgcatgcgg tataaatttc ttgctcagct cagaaaagat ttgtcgttta
      541 agaaaggcca tttcctccat tgtcaatgaa ggatccaatg ttggtaattc aatctcaaaa
      601 ttgttttttt cgacaatagg taattctaat gtgaatgatt cttcttcctt tatagtattc
      661 gtcacaagta gagactgatg gaaaatacta ggccggcgat ttttatattt attcttacgt
      721 atcctgtcaa cgataacttc tatttgatca aaaaagtacg attcatttac gtctccaata
      781 agttcggcta attctttgaa tgccttcgtt acaggaagct gattcttctg tacaaaaaag
      841 taattagcca aagtaagcgg gaagtgttct atagaggaaa gtgtgataaa acggtacttc
      901 tcatttcctg cagttgtcct cagcaattct gtctctcggc tgtttcttac tccataaaaa
      961 tacgcttctt tccgttcatc ttcgaaacaa tacgcccaaa taacttctcc catcgctaat
     1021 ttttgttcat caacagagag tctcttcaat tgttcagcta tggtttcagc agccgaagtg
     1081 gcttgttgca agtaatcttt aggatcaaat attggaaagt tcaaatgata tcttcgttct
     1141 tccctcttga ttaatcctgc atcgatcaat aaatcaagaa aatgggaaaa tttattttgc
     1201 gaaaattctt ttttcaattc tcttagaatc gtttcttgtt ctcgatgttc atatagataa
     1261 tcggtcaatg aagaaaaaag cggatcatcg gtcagttttt gataaaagtt ttccttattt
     1321 tttgaataat agttcatata tgttctcttt tctatccgtt ttattttact taaaaggctt
     1381 ttacgtaaaa aggaggaaga acaagagtca taattgactg ttattctcct ccatttcttc
     1441 ggcctttagt atgttctatg tttcttttta tatcaatcgc ttatccattc attttgaatg
     1501 cttcatacta ccatttgatt agctaaatac agccgtcaat tgaggtacga cttgtttttt
     1561 acgtgaaacg acacctttaa gcaaagcacg gttgttggtc aaagttgttt ggaaagcttc
     1621 ttctactttt tcttttcctt taccagcaac aagtaattct gaatcactgt ctaagatgtt
     1681 tgtgacaact aatacgaaca gatcgtagcc atttgctttc atttcatctt ccattgctgc
     1741 ttctagctct gcttgtcgat ccatcacttc attaaggtcc actgtattga cttgagcgat
     1801 acgaacgttg gaactgccca ttgggaaact ttttgcatcc aaatcaagaa gaaccgcagc
     1861 tgatttatca cttagatttg ttcctgcttt caacatttca agtccataag tgtttagatc
     1921 gacttcagcg attgctgcaa gttcttttgc agctgcttca tcttcaggcg tacatgttgg
     1981 tgatttgaac aacaatgtat ctgaaatgat agctgagagc atgattcctg cgatttcttt
     2041 aggaattgtt acttggtttt ctttatatag ttttaaaata atcgtacttg tacatccaac
     2101 tggttctgca cgatagtaca atggattagc tgtttcaaag tttgcaatac gatggtggtc
     2161 tactacagct aaaatattta cttcgctgat atctgaaata ctttgttgga attcattatg
     2221 atccacaagc atgacatctg cattttctgc tttagctgac tctactactc gtggtgcaga
     2281 tagctgaaag tggtctaatg cgtattgtgt ttcttcatta ggtgtaccta gagcaactgc
     2341 ttctgtttct ttacctaatt cattttgcaa gtgtgaaaac gcaatggctg ccccgattgc
     2401 atctgtatct ggattttggt gaccaaaaac taaaattttt gacatgtcat tcgctccttt
     2461 gtgatttctc ctatttaata atagcaaaaa aacggaaaga agcaatactt atcttctttc
     2521 cgatgcgacc tatcgcgtta aatattttgt atactcttct gtatgaagca atcgtttagc
     2581 attttcgaca cgttcttttg taggtggttc gatcccttct aatggatatt tcaaaccaag
     2641 tgtttcccac ttgtattttc ccatcgtatg ataaggaaga atctctactc tgtctacatt
     2701 tgacaaggtt tgaataaagt tgtctagtcg gatcaaatat tcatcataat cacttcgctc
     2761 aggaactagt acatggcgaa tccaaaccgg tttgttgatt tttgacaaat attgagccat
     2821 ttctaaaata ttttcattgt cccaatgcgt tagtttttta tgctcttcat tatcgatgtg
     2881 tttgatgtca aataacagta aatctgtata cttcatcaat tcttgaaaac gtgaaaagaa
     2941 aggttcttca tacgtaaaag gttttccgca tgtatccaat gtagtatgca tcttccgctc
     3001 ttttgctttt ttaaatagtt cgatcaaaaa atcgatctgc aatagaggtt ctccaccact
     3061 aacagtaata ccacctttat ctccccagta aggtctgaag cgttctgctt tatctaaaag
     3121 ttcatctgct gtgtattctt tccctccgcc aatattccaa gtatctggat tgtgacaaaa
     3181 ttggcaacgc atgcggcatc cttgcataaa cacgacaaag cgcagtccag gtccgtctac
     3241 tgaaccgaaa gtttcgatag aatgaacata gccgattgtt ttttcttcca tttaagttca
     3301 catcttttct ttgatttcat tttaagtaca agttagctgt cgaagcgaag ctttctgaac
     3361 aaaatttttc gcaattgccg cttcgttatg tgtaaaattt acagggacgg aacatacaag
     3421 tcctgcccct gtaaatcgtt tctttcaaat aagcatactg attattcgat tttgatgcga
     3481 tggctattca acgtcctttc gacgctaagt cgaaaaactt ttttcacgaa ctttttacat
     3541 tctgtcgtgt gaagttctca tcaagacatc taattgttgt tctcttgtca agtcacggaa
     3601 tttaactgca taaccagata cccggatcgt caagttcgga tatttcattg gattttccat
     3661 tgcatcacgc aataaatcat tactgaatac attgacattc aaatgataag ctccttttga
     3721 gaagtatcca tctaagacat tacgcaagtt ttcgattctt gtatcttgtt cttttccaag
     3781 acctgaagga ttgattgttt gggtatttga aattccatcc aatgcacagc cgtaattcat
     3841 tttagctgtt gagttcaggc tagctaataa cccactttgt tccgcattgt aacttggatt
     3901 tgctcctggc gcaagtggtt ttccagcttc acggccatca ggagtatttc ctgtattttt
     3961 accgtaaaca acatttgaag taatcgtcaa taatgaagtt gttggttttg agttgcggta
     4021 agttttatga cgtttgattt gtcccatgaa gtattccaag atccatgaaa ctaattcatc
     4081 tgcacggtca tcatcatttc cgtatttagg gaagtcgcca tccacttcaa aatcaactgc
     4141 tattcctttt tcattacgga ttgcttttac ttttgcatat ttgatcgctg acaagctgtc
     4201 tgccgcatga gagatcccag caatacctgt agcaaatgtg cgttgcaagt cagaatccat
     4261 caaagccagc tgagctgctt cataagaata tttatcatgc atataatgaa tgatgttcaa
     4321 cgtattgaca tatagttctg ctaaccaatc catcatattc atgaagttat gtttcacttc
     4381 ttcaaagtct agtatttctg atgtgattgg acgatattct ggtccaactt gggcgccagt
     4441 cacttcatcg actccgccat tgatggcata taatagtgtt ttagccaagt tagcacgagc
     4501 gccaaagaat tgcatgtctt ttccgacaac tgttcctgat acacagcaag caatcgcaca
     4561 atcatcagaa ccccattgtt cacgaagctg attatcattt tcgaattgaa tcgaagaact
     4621 ttcgatagcg attctgctag catatgttct gaatccttct ggaaggtgtt cagaatacaa
     4681 aacagtcaag tttggttctg gtgaaggtcc catatttgtt aatgtatgaa gcagacggaa
     4741 atcattcttt gtaactaatg aacgaccatc taatcccata cctgcaatgg ataaagtagc
     4801 ccagataggg aatcctgaga ataattggtt atattcaggt gtacgcgcga atttgaccat
     4861 acgtaatttc attactaagt ggtcgatcaa ttcttgtgct tctttttctg tgattactcc
     4921 attatccaaa tcacgttgga tatagatatc aaggaatgct gagatacgtc cgattgacat
     4981 cgcagcacca ttttgtgatt tgattgctgc taaatatccg aagtatagcc attggacagc
     5041 ttcttttgca tttgcagctg gtttagaaat atcatagcca tatttcgcag ccatttcttt
     5101 catttgcgct aatgcacgat attgttcagt gatttcttca cgtaaacgaa tcacttcttc
     5161 actcattgta tgataaccag tcatatcatg atcttttttc ttttgttcca tcaaatagtc
     5221 gattccatac aatgccacac gacgatagtc accgatgata cgtccgcgac cgtaagcgtc
     5281 tggaagccct gtaatgattt tgtttttacg agcagcacgc atttcagcag tataagcgtc
     5341 aaatacacct tgattatgtg ttttgcgcca gtcagtgaaa atatgtgtca attcatcgtt
     5401 tggtgtatag ccattgcttt ttagcgcatt gttagccata ttgattccgc cgaacggcat
     5461 gaatgcttgt ttcaaaggtt tgtctgtctg tagaccgacg attttttcca aatctttatc
     5521 caaatagcct gcatcgtgtg aagtaatagt tgatacgatt tctgtgtcca tatcatagac
     5581 accgttacgc tcgaattgga tatcatttaa cttttgcaat tcatcccata atttttctgt
     5641 tgcttctgtt gggccttcca aaaagctgtc atcaccgcga tattcagtgt agttattttg
     5701 aataaagtct ctagtgtcta cgccttcttt ccatttggta cctttaaatc cattccattg
     5761 ctccattgta tggacctcct aaatttctgt tttatgtaac agtttttacg tgattagtat
     5821 aacacagcac cctatctttg caagggtttt cttgtttttt atttaacaat ttttatgttt
     5881 tatttacata tatttaaatc aacgttgaca taccaacatt taagcattgt gaacactttc
     5941 atcttttttt gcaaacgtat aaggatttat taaaaatgaa tgaaaaagag acgccacctg
     6001 tattaataca gatggcgtct cttcattaaa atactacaac agttacgact cgatgaaaat
     6061 ctcaggagca tcgataactt cgatgacttc tccacctttt ttctcatcca tcgcaaatga
     6121 tccattcgat gttcgatcac ctatagggaa atcagttggg tcaatcgtta actgctgccc
     6181 tttttgattc atcaaggtta tttcttttga tcttccttcc gacatataga taatacggtg
     6241 cggatttttt ttcagctcac gcatgaccgt cactccccgc ttcgcacgtg aagtttggct
     6301 gatttcttga gcaagcatgc gtttaacagc tcctcgctga gtaacgatta cgatcggcgt
     6361 atcaccttct gctaacacaa gcagcccgtt gataatccta tctccatctt tcaaattcat
     6421 agacttcact ccagctgcct ttgctccaac aacgggaaca tctgttaaag gatagcgcaa
     6481 acccattcct tgatgcgtta ctaagaaaac atctaagcct ggctgatctt ctttcagata
     6541 cacagcaatc agttcatctt cttccgcctt tagcttcata cagctgagcg gacggctctt
     6601 ataggtgcgc catggttcga actctgtcat tcgtgtttgc ttgatcaatc cattcttgct
     6661 gatgaataca aatgttttct ctgcttgaat tttttgatat gggaaaacag ctaaaatcga
     6721 ttcgtctaca gacagattgg agattgtttg agaaatgtgc tcaccagcat ctttccattt
     6781 caaatcgggt agttcatgga cagggcggta gatcacattt gctttatttg tgatcagaag
     6841 aacatggtcc aatgtactca attcacctga gtatagcaag tagtcgcctt ctcgcatccc
     6901 gatttcttct ggtttggaag cactataaga acgaaggctt gttcgcttca catagccttc
     6961 tcgcgtcaca ctgacaatta cgtcttcttg tgccactaag acttgcgtat caattttgat
     7021 ttcttcgatt tcgtcttcga ttgtcgttag acgagcggaa gaataatttt ttttcacttc
     7081 tcgcaattct tttttcataa cagagaaaag ctctttgtca tttgaaagga ttttattcaa
     7141 ctctgtgatt tgcgcaatca agctttcgga ttccttttga agctctgtga tatccgtgtt
     7201 cgtcaaacgg tataattgca atgtgacaat tgcttctgct tgttcttctg taaattgaaa
     7261 gacgtcgact aaattctttt tggcgtcttt tttgtcttta ctttcacgaa tcgttgcgat
     7321 tacttcatcc agaatcgata aagctttcat caatccttct acgatatgct gtcttttttg
     7381 agctttggct aaatcgaatt gactacgttt tgttatgact tgctttcgat gctcgatata
     7441 acttcttaaa atgtctttca gtccaacttg atgcggagtc atatggtcga tagcgaccat
     7501 attgaaattg taattgatct gtagctcagt gtttttgaac aaataattca aaattccttg
     7561 agcattggcg tcttttttca attcgacgac aatttgcaga cctgttctat cactttcatc
     7621 tcgtacttca gctattccat cgattttctt attcaaacgg atctcatcca tttttttcac
     7681 caaggtcgct ttatttactt catatgggat ttctgtgatc acgatttgct gtttattacc
     7741 cttcattgcc tctatctttg ttttcgaacg aagaataact tttcctcgtc ctgtttcata
     7801 agcttttttg atttcatctt ttccttgcaa gatccctcct gttggaaagt caggtccagg
     7861 aatatattcc atcaattttt caaggctcgc ttgtggatga tcgatcatat agattgtgcc
     7921 atcgatcact tcagctaagt tatgagtcgg gatttctgtt gcatatccag cagatatacc
     7981 tgtcgatcca ttgacgagaa ggtttgggta tcgagctgga aggactgttg gttctttttc
     8041 tgtatcatca aaattccaca cgagatcgac tgtttctttc tcgatatctg ctagcatctc
     8101 tccacttaac ttggataatc tggcttcagt ataacgcatc gcagcaggtg gatcaccgtc
     8161 catactcccg ttattcccgt gcatttcgat cagtacttcc cgcaacttcc agtcttggct
     8221 catgcggacc atcgcttcat aaatactgat gtcaccatga ggatgataat tccccatgat
     8281 atttccgaca gattttgctg atttacggaa tcctttgtca tacgtattgc catctttgtt
     8341 catggcaaat aatatccggc gttgcactgg cttcaatcca tcacggatat caggcagtgc
     8401 acgttcttgg ataatatatt tggaataacg tccgaagcgg tcacccatca cttcttctaa
     8461 agttaattct tgtacttctt gtcgattttc catcaggtga cctcctattc tacttcaaat
     8521 aactgattgt tttcattttt atctgctcgt tcttcatcta ataaatcatt agaaactgaa
     8581 ggagagattt cagtatcctc ttttttatct aagatactgc catcttcttc gagcgtaaat
     8641 tgcacgtgat tttcgatcca ttttcttcga ggttctactt tgtcacccat cagtgtggtt
     8701 actcgacgtt cagcttgcgc agcatcatcg atacggacgc ggatcaacgt acgggaagtc
     8761 ggatccatcg ttgtttccca caattgttcc gcattcatct ctccaagtcc tttatatcgc
     8821 tgcagcatat atcctttgcc gactttttta atcattgctg ccaattcgtc atctgtccac
     8881 gcatattcaa tgacttgctt ctttccttgt cctttggata ctttatataa aggcggtaac
     8941 gcgatatata ctttcccagc ttcaatcagc ggtttcatat aacgataaaa gaaagtaagc
     9001 agtaatactt gaatatgggc gccgtctgta tccgcatcgg tcatgatgat tactttgtcg
     9061 taattacagt cttcgataga aaactcagga ccgactcctg caccaatcgt atagatcatc
     9121 gtattgattt cttcattttt caagatatct tgcattttag ctttttcggt attgatgact
     9181 tttcctcgta aaggtagaat tgcttggaac tttctgtctc ttccttgttt agcagatccg
     9241 ccagcagaat ccccttcgac taaatacaat tcatttttct tagggtttcg ggattgtgcg
     9301 ggtgtcaatt ttcctgaaag aagagattcg ccttttttac gcttcttccc atttcggctt
     9361 tcttctctgg ctttacgtgc tgcttctctc gcttctctgg ctttgattgc tttacggacc
     9421 aacatctggc tcatttcgct attttcctgc aaataaaagc ccatttgttc actgatgacg
     9481 ttatctacta cggtacgagc aactggcgta ccaagttttt cttttgtttg cccttcaaat
     9541 tgcagaagat tttcaggtac acggatagaa agtacagcag ctaacccttc tctgaaatca
     9601 ctaccttcca gattcttgtc ccgttctttc agcaaaccaa cttttctcgc atattcatta
     9661 taagatttcg tcatcgccgc tttcatacca gcttcatggg ttcccccatc ttttgtccga
     9721 acgttattga caaaagataa aacattttct gaataaccgt cattgtattg ataagcgacc
     9781 tctacttcga taccttcttt ttctcctgaa aaataaacaa ctggtgtcaa tgtatctttt
     9841 tcttcattca gataatcaac aaattctttg attccttctt cgtaatgaaa aatttccttg
     9901 actggttctt ctccacgaag atcagaaaga gagattttaa cgccttttag aagaaaggca
     9961 gattctctta accgttcggc taaaatttca tatgaaaatt tcgttgtact gaatattgta
    10021 tcatctggta aaaaatggac agtcgtcccg tttgcttttt ttgtttttcc tatctttttc
    10081 aaagtaccgt caggtttacc gccgttttta aatttctgct gatactctac gccatctcta
    10141 acgatcgtta caattagcca tttcgataag gcatttacca cactggctcc tacaccgtgc
    10201 agtccaccag aagttttgta ccctccttga ccaaactttc cgccagcatg cagcacagta
    10261 aaaatcactt caactgttgg tattccggaa gcatgcattc ctacaggcat cccacgtccg
    10321 ctatctgcaa cagttatact attgtcttca tggatggtca catcaatctc actgccataa
    10381 cctgataatg cttcgtcaac tgcattatcg acgatttcat agactaaatg atgcaagcct
    10441 cggctgtcag tggatccaat gtacatccct ggtctttttc taactgcctc taatccttcc
    10501 aatacttgga tggacgagtc attgtattcg ttgtttactt tttttgccaa ggcaaacgct
    10561 ccttcaataa tactttgcgg caaaaccgca ccacgattat catactagaa aaggtcgtga
    10621 aaaaaaagag ggtagacgag aaatcaattt taattatctc ctaaccgctt tttcgacatt
    10681 cccctctatc gatcatctct tctttgtggt catttttatt tttggttttc tttcaactta
    10741 ccaagttcaa tcttaataca acgatccatt acgatatctg tacgtcctgc ttttcttagc
    10801 atctcagctg cttctttgtt ttcaatccct aattgtgccc agaacacttt agcatcagtt
    10861 ttcaaaaaat cacctgctat ttcaggtaaa aattcactcc gtctaaatac atctacgata
    10921 tcgattggat catcgatttc tgtcaaattc gcatagactt tctcgcctag aatttcttca
    10981 ccagccaata atggatttac tggtatgatt ttatatccat tgtcttgcaa tacctgtgca
    11041 accatgtaac ttgttcgttc tggtttattg ctcaagccta cgacggcaat attttttgct
    11101 tcttccaaat agttgaaaat cgtttcttgt gttggatttt ttacagacat ttctgccacc
    11161 ccttgctttt ctttttattc catctattat acttgtatct ttcatttttt caattgttcc
    11221 tgttacctat tcatgctaaa ataaaggata gttttcaact tgaaagaggg taaaaaatga
    11281 aattgatctt attacttatt ttagcatatc ttttaggttc tattccttcc ggtgtctgga
    11341 ttggcaaatt gtttttcaaa aaagatatcc gacaacacgg gagcggtaat actggaacga
    11401 ccaatacatt tcgtgtatta ggcaaaacag ccgggattgt tgtcctgctt atggatattt
    11461 taaaaggtac attggctact tgtttgccga tgatcttcca cctttctggg attaaccctc
    11521 tttggtttgg ggtatgcgcc attcttggcc atacatttcc gatttttgct gggttcaaag
    11581 gaggaaaagc tgttgcgaca agtgcaggaa tgcttttagg atttaatcct gtattttttg
    11641 tttattcttg tatcatcttt atcgttagtt tattttgtac aagtatggtg agtttgagca
    11701 gtatgatcag tgcagtattg atcactttat ctacgatcgt ccttccttat gtagctcctg
    11761 tgattttggc taagcccaat tggttactga cgatcattgc ctttttagtt tcttccttta
    11821 tcttttatcg gcataaagac aatatcaagc gtatcagaaa ccatactgaa agtcgaatcc
    11881 cgtttggttt gaatagcagc aagaaaaaat cctgatactt tttcattcca aagagataaa
    11941 acgggagtgt gacaaatcga tgtcacactc ccttattact tacaggatag cttttttaca
    12001 caccttggta aacggtgttc cctgctaact tctcggtcac aacctcttac ttcactgtga
    12061 tggaatattt tgtcttgaag atttcatggg cacctagttg attgatccct actttttcca
    12121 tcaagtttcc actactgttc accgtgtcag cgattccgca ccacggttcg atacaaacga
    12181 aaggcgcttc ttttggataa ggagaccaga tccctacata aggcatatct ttatagctta
    12241 aagttacgct atgggaagat ttttcacttc gaatggcgta cgcatttaga ccccttgttt
    12301 caaaaaccaa ggcatcttgc tcaaaaagtt cacgattcaa agccagattc gtatttgtct
    12361 gacctaacgt cttttgatcc atatcgatga atgggccttt caatggtagg cgtaatcttg
    12421 atttcaatgg agaaaatgcc agatagaaat cttcaaatga caatccttct tcaagaggta
    12481 cattgaaagc aggatgtcca ccgatagaaa agaacatttc tttttcaccg gtatttgcca
    12541 cttgataatg aaccgtgatg ccgtctcctc ctaattcata gctgatcact aattcaaaat
    12601 caaatggata cttttctaat gtctccggcg tactccttaa gatgaaacta gccatttctt
    12661 gtccatgttc aatgacttca aaatccatat cccgagcaaa tccgtgttgc cccatttgat
    12721 atgttttccc ttgataaaca tactgatcat cttttaaacg tccaacaaaa gggaataaaa
    12781 ccggtgcatg tctgccccaa tacgctggat caccttgcca gatatactct aaaccatgtt
    12841 cttttgattt cagactgatc aattccgcac cgtgttcagc gatttcggcg atcagctggt
    12901 cattttgaat aataacagtc attgccattc ctccaacttc gacttacttt ttaaaatggg
    12961 aaggctggaa caaacatttc tatctgcccc agtcccctta cttctaataa ctgtgttttg
    13021 ctaactcgtc tttaaaacgg gaattcaata cttttaaata agttcccttc atgcctaacg
    13081 aacgagattc aatgattcca gctgattcca attttcgtaa agcattgacg atcacagaac
    13141 gagtgatgcc gatactatcg gcaatattag aagcagtcag acgaccttca tctccatcca
    13201 atgcttcaaa gatagcttgt acagccttca attcgctata agataatgtg ttgattgcca
    13261 tttggacagc cgttgcactc cgtacatctg cttcgatgct tcgagacttc tgataaagga
    13321 tctgcatacc gacaaccgta gctccatatt ctgctaagac tagatcgtca tctgcaaacg
    13381 attgttccat acgagataag ataatcgtac ccaaacgttc gccagctcca aagatcggaa
    13441 cgacagtcgt cagaccaaat ggatatttct ctcttgactc taccggaaat gcagtaatat
    13501 cactagtaat tgggatatta gcttcagttt tcatcaactg tgccactgta tcagtataag
    13561 attcaggaaa ttgtttctca acaaacattg ttttgattcg ttcattgttc acatcgtgac
    13621 gttcattata acctagtaat actccgtcac ttcctatgat ataggtgttg ctgtcaagaa
    13681 taccacctag tgtgacagcc attttatcgt aaggcaaatc tgcttgcatg tcaaaagtat
    13741 tcttttgctg caaaagtgtg tttatcttgc gggttttcgt tagcaagtct gtcattgtcg
    13801 tcctccgatt ttttataaaa tatagcgact taaatcttca tttgccgcaa ttgagccaag
    13861 tttgtcatcc acatatgctt ctgtgatcgt tatttctccc atttgcatat ctggtgcttc
    13921 aaataataga tcttctagta gtttttccaa aatggtatgc agtctgcgtg cgccgatatt
    13981 atctgtgtca cggttgacat cgaaagcgat ttgagcgatc cgttcaattg cttcttttgt
    14041 aaacgtaact gacacatttt ctgtaccgat caacgcgacg tattgtttta ctaaagcatt
    14101 atttggttcg gtcagaatct tcacaaaatc ttcagctgtc aaatcatcta attctacccg
    14161 tatcgggaag cgtccttgaa gttctggaat tagatcactt ggtttagaca aatggaaagc
    14221 tcctgaagca atgaatagga cgtgatctgt ttggatgatc ccgtattttg tgtttacttg
    14281 tgaaccttcg acaattggca atatgtctct ttggacgcct tctctggata cttctccaga
    14341 ttgctgtgat ttagaagtga tcttatcgat ttcatcgata aaaataattc cactttcttc
    14401 cgctaatttg attgcctcac tatggatatc agcatccttg actaattttg ctgattcttc
    14461 cttgatcaat aactctaaag cttctttgac tgttaccgtc cgttccactt ttttcttcgg
    14521 tgtcaaagca cctagagttt catttaggtc gatccccatt tgctccaatc cattgttcat
    14581 cattggtgca ggtttctttt ggtcttcaac ttcaatggtt acttcacgac tatccagtaa
    14641 acccttttgt agttgttcca agactgtacg gcgattgatt cgaatatctt ctgtcacttc
    14701 ttcttgcggt tcagcggtat tttgctgact agcattaaaa agattcatca tttgttcaaa
    14761 ttgattagtg gattgtttct gttctttttt gataccaggt accaagattt ttaccaaacg
    14821 tttttctgca ttttttttag cacttgtgta tacacggctg tactgctctt tttctacgat
    14881 ttggatcgca ttttctacta aatcccgaac cattgattct acatctcttc cgacataacc
    14941 gacttcagta aattttgttg cttcgacttt gacaaatggt gcattgacga tttttgccaa
    15001 acgtcgtgcg atttctgttt taccgacccc tgtaggtccg atcatcagca tattttttgg
    15061 tgtaatatct tgttgcattt tttcatctaa ctgcaaacgg cgatagcggt tacgcaaagc
    15121 aacggcaaca gatttttttg ctgcgtgctg tcctacgata tattcatcta attcacttac
    15181 gatttgtctt ggtgtttgtt ttaattcata catatctact cacctcttac agttcttcta
    15241 cgataatatt atgattagta aagatacaga tatctgcggc aatatttaac gcattttctg
    15301 caatttcttt cgcactcatg tcgttttgag catagttttt cattgctcgg gctgcagcca
    15361 acgcaaaatt ccctcctgat ccgatagcta agataccatc atctggtgtg ataacttctc
    15421 ctgtacctga aacaagaagc atttctttat cattcattac gatcagcatc gcttcaagtt
    15481 tttgcataga ttgctgtgtc cgccattctt gagctaattc gacagctgcg cgttgtagat
    15541 tcccgttata ttcgtttagt ttgccttcaa atttttcttc taaagtaaac gcatctgcaa
    15601 cacttccggc gaaacctaca acaacttctc cattgtagat acgtcgtact ttctttgcag
    15661 tgcctttcat gacaacagat tcacccattg ttacttggcc atctccagcc atagcaaatt
    15721 tcccgtcttt ttcgacggca cagatagtgg ttgaatgaaa tggtgattcg accatgtttg
    15781 tttcctccta aatttgttct tttccttatt tttacgctct tggatggaaa gaacgatagt
    15841 ttttttgtaa actttctttt gttacatggg catagatctg ggtagtcgat aaattggcat
    15901 gtcctagcaa ttcttggact gtccgcaaat ctgccccatt atttaataaa tgagtagcaa
    15961 atgtatggcg cagcatgtga ggatggatat cactatccaa actgcttttt ttgatcattt
    16021 gattcaagac atattcaatt ccagtaggcg tgattggttt tccatgatga ttcacaaaaa
    16081 cgatatcatg ctcttcgtga tattttgtca tcaatacctg gcggccttcc ctgaaatatt
    16141 cttgcagagc atcttgagca aaagaaccta gaggagcata tctctctttg ttccctttac
    16201 catggatcaa catgacctct gaatcaaaat caatgtctga taccgacaaa ctgctacact
    16261 cacttaaacg gatgcctgac ccgtaaagga cttccagtaa agcgcggttc ctcaaatcca
    16321 aaggactatc tcctgctacg ctgtcaaaaa gtgcttgcat ttcattttca taaaaaaaac
    16381 gtggcagtct caaatttttc tttttgagat gaacgtaaga aaatggattt tcttttatca
    16441 cttcttcttt gagaagatac tgataaaacg aacgtaggct ggctatcttg cgactgatag
    16501 aatttctgct atagctagga cgatgatcag ctaatgcact caaatagaca cgaaccgtaa
    16561 aatattccgc cttcagcaga tcagcgtctc cagattcctc caaaaaatgt ttgaaatgga
    16621 gaatgtcttc ttcatatgct tctttcgttt tttctgaata tcctctttcg acaatcaaat
    16681 aacgcaaaaa tttttgttcc cacgtggctt ctgtcatttt ctcaccttcc ttttgtccca
    16741 gagaataatt tagcacagcg tttataaaaa gacaaataaa ttgtcagaat ttaaccaata
    16801 tttctaagtt tgttcacaat tggcgcaatt cctcacattt tgtttgagaa attcttaaga
    16861 aaaacgcaag aaaaagagcg agactatccg tctcaccctc ttcatggagt ttccttactc
    16921 atttgggatt gcagtttttt ctaattctgt ttttattgcc tcattagctt ttaaagctcg
    16981 ttgtgcaatt gcttcatatc ttgctttttt gtctcgaatg cgctctggca gttcaggaaa
    17041 cagaccatag ttggcattca tcggttggaa atgttttcct tccgcatgag taatgtagta
    17101 agccatactt ccaatagctg tttcttgtgg aaactcgact ggttccattt cttttgctaa
    17161 gcgtgcggcg ttgattccag caagtagtcc gctcgctgca ctttcaacat agccttctac
    17221 accagtcatc tgacctgcaa agaacagatc ttcgcgtttc gttgattggt aagtcggttt
    17281 cagcaattct ggcgaattca taaagctgtt tcggtgcatc acaccatagc gaacgaattc
    17341 agcattttct aacccaggaa tcatccggaa aacacgtttt tgctcgcccc atttcaagtg
    17401 agtctgaaag cccacgatgt tgtataaaga agctgcagca ttgtcttgac gcagctggat
    17461 aacagcataa ggacgtttgc cagttttagg atcttccaat ccaactggtt tcataggtcc
    17521 gaaaagcatc gttttgaatc ctcgctgtgc cattacttca attggcatac atccttcaaa
    17581 atatttttct ttctcaaaag atttaagttc tgccacttcg gcattgatta gtgcctcatg
    17641 gaaagctttg aattcctctt ctgtcatcgg acagttcaag taagctgctt ctcctttgtc
    17701 atagcgggac ttcaaatata ctttatccat atcgatcgta gctttgtcta cgattggtgc
    17761 agctgcatca tagaaataaa aaccatctga accattgaat gctttgatgc tttctgctaa
    17821 tggatgagaa gtcaaaggtc ctgttgctac tacggtgatt ccttccggta tttcagtaat
    17881 ttcttcgttt atcactgtta ctaatggatg ctctttgact tttcgggtaa ttgtttcaga
    17941 aaaagaatcg cggtcaacag ctaaggcacc accagctggc actgctgttt catctgccga
    18001 agtgattact accgaattca atcggcgcat ttcttctttc aataacccta ctgcattagc
    18061 caaactgttt cctcttaatg aattggaaca tactagttca gcaaaattac ttgtgtgatg
    18121 cgcctcagtc gatttgactg gacgcatttc atataaacgg acagggactc ctgcttgtgc
    18181 gatctgccaa gcagcttcac ttccggcaag ccctgctcca acaacattta ccattttcaa
    18241 tgaaagaacc tcttttctat tatttttgga tgtcttcttc gtaatctcca tttacacaga
    18301 ctacttgttt accgcctttg actttcttct cgaccagata tccgtcacat tttggacaat
    18361 ttctgcccac tggtttatcc caagaagtga attcacattc tgggaaacgg gaacaaccat
    18421 agaatagtct gtttttctta gattttcgtt caatgacttg tccttcatga catactgggc
    18481 aagtcacacc gatttctttt acgattggtt tcgtattccg acaatcagga aaattactgc
    18541 aagcataaaa cttcccatat ttccctaatt ttatcaccat cggatgtcca cagacatcac
    18601 aatcgaatcc tgctggttca tctttgattt gaattttttc gattttttct tccgcattcg
    18661 tcagttcttt ttcaaacggt ttatagaaac gatcaaccac tttgacccac gcttccgtgc
    18721 cttcttcaat tttatccaaa tctccttcca tttctgctgt gaaatggata tcgacgattt
    18781 gagggaagaa ttcacagatt aatgaattga caatttctcc tagttcagtc ggctcaaatc
    18841 ttttttgtgt caattttaca tagtagcgtc tttggatcgt atcaagtgtt ggtgcataag
    18901 tggaaggtcg ccctaccccg ttttcttcta gtgcacgaat caacgtagcc tcactaaaac
    18961 gtgctggtgg ttgagtaaaa tgttgttttg gttcaatatc aacagattgg actacatcgc
    19021 cttcttcaag ttctggaaga atattttctt tctcttcttt gccgtcatct ctaccttcca
    19081 catacacttg catgaatcct ttgaatttga tttttgaacc gttcgcaatg aagatgacac
    19141 cattttgttc taatgtcact ttcattgtat ctaaaatagc tggtgtcatc tgactagcca
    19201 caaaacgtga ccagatcaat gtataaagtt tcaattgatc tttatctaaa tattgtttga
    19261 gttcatctgg tgtacgaagc acactcgttg gacgcacagc ttcatgggca tcttgtgcgc
    19321 cttgagcatt tttgatcttt cggtgaccat gtctagaaaa ttcttttcca tacgtatctt
    19381 caataaatgc tgcggcctct gcttttgctg tatcggcaat ccgggtagaa tcagtacgca
    19441 tgtatgtaat caagccgact gttccttgtt tacccaaagt gattccttca tataattgct
    19501 gtgctaccat catggttttt cttgttcgaa agtttaactt acgggcagct tcttgttgca
    19561 ggctacttgt agtgaaagga ttcgcagggt ttcttttgcg ctctttcttt tctacttttt
    19621 taacttcgaa gtctgttcca tcaattctag cagtgacttc ttttacactt tgtgcatctg
    19681 gtaatttctt tttcttaccg tcgattcccc agaaatttgc tttgaatttc ttgcgagctt
    19741 ttttaaaatt accgtcgatg ctccaatatt cttctggaac aaattctcgg atctcttttt
    19801 cacggtcaat aataattttt aaagcgacag attggacacg tcctgcactt aaccctttct
    19861 tgaccttacg ccagagaata ggactgatcg aataaccaac gattctgtct aaggtacgac
    19921 gagcttgctg tgcatctact aaatctacat cgatcgttct tggttcctta aaagctgctt
    19981 tgactgcgtc ttttgtgatt tcattgaaga ccacccgatt tttttctttc agatccaacc
    20041 caagtaggta cgctaaatgc caagcaatcg cttctccttc tctatccggg tcacttgcca
    20101 agtaaacttt ttgagctttt tttgctgcgg ctttcaggct tttgatgaca tcgccttttc
    20161 cgcgtataga aatataatgg ggttcataat tgttttcaaa atcgataccc attttacttt
    20221 tcggtaaatc tcttatatgg ccaacactgg ccattacttt atagtttcgt ccaagatatt
    20281 tctcaattgt cttggctttt gcaggtgatt ctacaatcac taaatattta tacgccatta
    20341 ctgaatggac tcctttccat tgtcgtgttc ctactattaa aagaggattc atacaaatcg
    20401 tagctaatca tatccattca gaaaacgttt gtcaagaaaa gcaaatgaaa agtatggtgt
    20461 tattctttaa attctgccaa gatatcttca cccgaaaccg tgcaaactgc accgtcttgg
    20521 atcaaatgat gacatccggt agaatgttct gttaaaatat ttcctggaac agaaaaaact
    20581 gttcttccaa gatccaatgc ttgctgtgct gttatcagag agccgctttt tttcttggct
    20641 tcaaagacac atgttccttt agacaaagct gcgataatcc gatttctcat tggaaaacaa
    20701 tgctttttcg ggccggattg aggaggatat tcactcaaaa gaagatgatc atttgcaatc
    20761 acctcttgca agtcacgatt ttcagcagga tagacttgct ctatccctgt tccaatgact
    20821 gcgattgtcc gtccaccatg agagattgct gcttggtgac cgtatgtatc tatccctttc
    20881 gcgcagccac tgacgatcac atatccagct tctatcactg gttttagtaa ataataaact
    20941 gtttttttgg ctaaagcaga agtgtgtctt ccaccaacaa cgcttaacat gttacaagaa
    21001 agtaaagata gatcaccatt ataaaacagt acaattggcg gataggtcaa gtgaagcagc
    21061 tgagggggat atttgggatc aaagcaagtg ataaacgact gtttcgattg gattttgccc
    21121 cagttagcgt gaatttcctg ccaacttttg cgaaacagct cccggtgttt ggttatttta
    21181 cctatcttaa tgatgtcttc aaatccgatt tctttataag gatactgcat catccagtta
    21241 gcaagtgccc attttccttg actactgatt ccttttgtat aagcaagttt caataaattt
    21301 tcttctattt gatacatcat aaaaccgcct ttcgtctctc tttctaataa gatacgtaaa
    21361 agcggctgtt ttttattgta aatatttttt tacaggtgca aaacttttac gatggattgg
    21421 cgtaattcct tgtcgttcaa gtccttctaa gtgttccttt gttccataac ctgcattatg
    21481 cgagaaacca tatccaggat aaagcacgtc atattctttc atcaattggt ctcgatatac
    21541 tttagcaatg atacttgcag cagcaatcga cacagatcgt gcatcccctt tgattatttt
    21601 ttcctgctga ataggcaaat ccaaggtcat cgcatcgatc aacaaatagc ttggtacaat
    21661 ggacaatttt tctactgctt ggatcatcgc taatttactt gcttcataaa tattcacatc
    21721 atcgattgtc tgctgatcaa cgatcccgat cccgattgcc agggcttttt cttgaacttg
    21781 ttgataaaga agttctcgct ttttctctga taattgtttg gagtcattca gccctaatat
    21841 gatctcattt ttcggcaaga taactgcagc tgccacgaca ggtccagcta atggtcctct
    21901 tcctacttca tcaatgccgg caatccattg gtgaccttgt gcgtaccctt gcttttcaaa
    21961 gcaaaacatt tcttcatatt tttccttaat taatgcttcc tttttcaatc gtcgttcaaa
    22021 agaagccagt gcttgctgca cgcctttgcg tggatcattt cttaatgatt ctagtgtagg
    22081 atcatctatt ctctgtatgc ttttcaatcg ttctttgata ctttggatgg attcagtcat
    22141 cacttttttg ctccatttct tcgcaacgat ccagtgtgta tcgtccaagt tttccttgac
    22201 gaatatcatg cacgactaat tcgctgccac gatcatagtc ttctttatac ccacgttttg
    22261 ctgtaatatc catcagtaat tccggtgcca atttttcttc ttgctcgatt gataaaccat
    22321 aacgatcgct gattcttcct gaataatatc gggcaaaaaa gtctaatccg taaatcgcta
    22381 aatcatctaa atggacaagc tggtctttga tcgcgcctgt cagcgctagt tttttgccga
    22441 tttcttcatc ttcaaatttg ggccataaaa tccctggtgt gtctaacaat tccaactcat
    22501 tacctaaacg aagccactgc tgaccttttg ttacgccagg cttatttcct gtctgtgcaa
    22561 ttttcttgcc tactagtcga ttcatcaacg tagatttccc aacatttgga atacctaaga
    22621 ccattgcccg aatagcgcga ggcttgatcc cccgagcagc atctcttgcc cgtttttctt
    22681 tcaatgcttc tttagccgca ggtactagac ctttaattcc tttactttct tgtgccgtga
    22741 tagctaatgc aagatggcct tgtttacgaa aatattcttg ccacagcttt gtctgttgtg
    22801 gatctgccag atccgcttta ttcaataaaa caaggcgagg tttttgctga atgatctgat
    22861 ctagcattgg attacgagaa gataaaggta atcgtgcgtc taccaattca aatacgatgt
    22921 ccacatattt cattttttca gaaacttctc gtcgggcttt tgccatatgt cccggaaacc
    22981 attggatggt cattgttctc tccattcctt tcataccgga atattccccg gctttacttg
    23041 tttttttctt tttcaatata aattcacttt tttattatct taattgtcaa attaagttag
    23101 acaaatcatc aatacttacg taactcaaaa atacttccaa aggtgttcga taattcagtg
    23161 attttctagg aatattattt cgtttcgatg cgacagattg aataaaagat tcatctactg
    23221 aattgaaatc catagatttc aataaaccat ctctacgtaa caatccgtta gaattctcgt
    23281 ttaggcctct ttgagacggc gttcctggat cagcgaaata aatggcaata tcattggcat
    23341 tactgatctg tttccaattt gaaaattcct ttccacaatc aaaagtgatg gatttgaata
    23401 gatttttcgg tacagattca aaccaatgat ttaatttgtt ttcaatatca atcgcttgtc
    23461 taccacacgg tttcaatgtg atgataactt ttgataatcg ctcaactaag gtaattacag
    23521 cacttttatg tttcaaacct acgatagtgt caccttcaag gtgaccaaac tcatttgaga
    23581 attggctata atctttttca cgttcatgaa tagagcgacg gaaagcttgt tttccacgtc
    23641 tttcttgatg tccatttggt ttacgcttgc ctttcatcgg taagtcagaa ggattaaata
    23701 gccccttttt gaacatacga taaatggtac gagcagaaca acgaatagga aacgctgcac
    23761 gaccaacaat cacatcgggt gtccatcctt gaacaacctt tctttgaata tattctgatt
    23821 gttcctcagg taaaacaagc gggcgtctac cacagtttga tttgtttttc ttatactgtt
    23881 gatagtactc taaggctgat tttccttgct tgaagaacag gtatacttta tggatcgttt
    23941 gtcttgaacg attcaagaaa tgcgcagttt tcgcaacaga ttgatttatt ttgaaataag
    24001 actctatcat tacaagttca tccgttgtaa gatgggtata ggtcatttgt actcactcct
    24061 tataattctt tggacggaac tattttgagt gtagcacaaa tgactttttt agttgtctag
    24121 cttaatttta caatcggcgt tataaagaaa ttccatctat tagttaagtg aaagtgaacc
    24181 agtcctcatt ctatcacatc ttcacttttt tgatgatgca aatttttatt ttggtttcta
    24241 tatatgaatc taaatttttg acagcgtttc ctaaataaga gatgatagac gaacaaaaca
    24301 gaaaggagac gaaacaaatg aatagtatgg tttttgttaa ttttcctgtt gctgatgtca
    24361 atcgttccgt tgctttttat gaaaagctgg gttttaaaaa aaatgaagaa ttttctactg
    24421 aagaagctgg ttcaatggta tgggatgaca ctttttggat aatgcttctc tctcatgatt
    24481 tttataaaaa atttataaaa gataaagaaa tagctgataa taaaaaaaca agtggtgctt
    24541 tgatttcgtt tagtgttgaa aatgcggatg aagtaaaaaa atttgctcaa attgcaaaag
    24601 aaaatggtgg tactttccac gaagtagata tgggaatgcc tgaagaagaa atgttttcat
    24661 tagaagtcca agatctagac ggaaatacat tagaacccgt atggatgaag atgtaagcag
    24721 ataactaatc tgacgttttt tataacaaaa aaacaaaggc ggatgatacg ataagtattc
    24781 tccgcctcta ttttttttat tcgtacaatc tcttttttac agtttataaa agcagtcttc
    24841 tcaccctttt tttaattgtt agatgccagt gtatgtaaat caccaatgtg tcatgacaca
    24901 ttggtgattt tatggtatcc ttttattatt aactgacaaa ggagagaata ttttgaacac
    24961 tttgattgca aaagacgttt ttagattgcc cgaaatgaat gcaagattgt tgtcgacctc
    25021 tgctctttta ttagcccttg atgtcatctt atacaagata gcgattggtc ctgcttattt
    25081 tcaaatcaca ttcggatttt taagtatggc gcttatgggt tatctatatg gaccgatctg
    25141 ggctggtttg cttgaaatgt tgtcgaacac tttaaatttc acgatatttg gttcaggaac
    25201 gtttcaagct gcttttctta tcacggcttt ccttggtgga tttattaatg gcttattttt
    25261 atatcataaa aagataaacc tgccttccgt catcgctgcc caattattga ttatgatccc
    25321 agtcagcctt tttatcaatt cttggctgat gtctgttttg tttggtgcag atttcaaagt
    25381 aatttttcta ggtagattca tcaggaatat gatccaaatc cctattcaaa taatggttgt
    25441 ttattcattt atcaaaactt tagaggctag aaaagtgttt aaacgagctg tttgatttta
    25501 cgtactaagg tagtaaactg attttggatt aaacaataaa gcgtgcagtc tcaacagact
    25561 gcacgcttta ttgtttctca ctggatccat tttatttcat caagtggata atagacaaat
    25621 cttgctttac ctagaatatc agttttattg atcgtgccaa acgaacgact atcttttgaa
    25681 actcttcgat tatctccaag tacaaaataa ttatcttccg gaagcttgga ttgtcccgtt
    25741 agctcttgta gtgtaaagtc cgtcgtatag gatgcatttg catgatctga tttcaggttt
    25801 ttagttagat aaggttcctt aactactttc ccattgatct tcaattgatc attttggtag
    25861 ctgacatttt ctcctggaag accgattact cgtttgatat aaatcgtgcc atctgctaat
    25921 tgaaaaacaa caatatcaaa tcgtctgatc tccgaaaatt tttccatcac aaccatatca
    25981 ccttgcttca acacgttttc cattgaattg ccttccactg gtaccgggat gaataaaaat
    26041 ccccgcaaca tgaacgcaag gaatacagaa acaagtaagt atttgaatac aagccagaag
    26101 cgattaatat agcgttgttt ttttgtcaat ctctatcaat ccatccctct ttttttcatt
    26161 ctttctttat tataagaaaa atatcaaaaa aatgcgacta gatagctgaa ataaaaataa
    26221 ttctttcaat taggctattg gacaaaaaac ttttttgatc ataaagtaca aaactatctc
    26281 ttatatgtca tgattatttt ctaaatattt ttcccatgct tcgtcaaaga tatccatgga
    26341 cggcaaatag tcgacattca gttccagata attagaaatt tcttcgtagc tagagctgtg
    26401 cttaggaaat tggatgtctt taccggcttc tgtagcgaaa acagataaag catcatgtgt
    26461 gccaccgcct cgcagtgtca ttaaataatg aaaaaagctt cgattcaccc ttcgttcctc
    26521 caattttctt cgataaaggc agcccggcgt gcatggtttc ttttaaaatt ttcaggatgc
    26581 tttttataat actcttgatg gtcttcttct gctagataaa atggttgggc tggttcgatt
    26641 tttgtaacga ttggctgttc gaaacgtcca ctttcagcta actgtttctt acttttttca
    26701 gcaatgatcc gctgttcttc tgtcaaataa aagatcaccg ggcgataatt gtcaccgcga
    26761 tcctcgaatt gtccgaaagc gtcagttgga tcagtttgct gccagtaaag ttctactaat
    26821 tgttcatatg aaatcaatgt tggatcatag ataatctcca ctgcttctgt atgtccagtc
    26881 gtttggcttt ttacttgttc ataagtcgga tctggtacat gccctccagt atatcctgac
    26941 atcactgtat ggataccagg aagcgtgtcg aaaggctgga tcatacacca gaagcagcct
    27001 cctgcaaata ttgctcgttc cattatgatt ccccctctaa tactactcat ccgatgattt
    27061 tttattttct tttgtcttgc tttcagtact gctggtgcta gttttgttgg tatttgagtt
    27121 gtttgaagca tcagaggtat cttttggcaa atatagacta aaccgaatgt catcatttac
    27181 taagtcgatt ttatctgctt taatatacat cccgttttgc attcggaatt gatccaacct
    27241 aagcatgata gtcagatcat ctgtattgac ttcgatccaa tctggtaatt tatagtttct
    27301 cttgatcata ttcatcacat ctttgattgg caaactcaat gttccgatag aaagacttct
    27361 agcttttagt tggacatttc cgttttccat cacatacgga tcaaaatata aatagaaatc
    27421 gataggaaaa cctagtactt cgaaagtacc attgagtagt gcttcatttt ccaaataaaa
    27481 tttatattca atatcactat ctttttgata ctcactaagg aaaaagctga tgatttgatt
    27541 gactttttct ttatttgaat tgatcgttaa gacaggatct ccttgtcttt ccgtaagagc
    27601 tggtatttct gggagttctg gttcccgatt agcaaaaata cggctgccta aaaatacggt
    27661 cgaaccaagt actaccccaa gaaggataag gaaggcgaat ttccagtaat ttgttttctt
    27721 tgttttgttt gaagatacgt cagatcttgt tttcatgttt attgatcatc ctccttctct
    27781 aaccattggt tttgtgtctc gatcagctga tctctcactg catttgccat caattgataa
    27841 cctaaattat ttggatggaa atgatcttct tcatagagca cattattttt gatgccattt
    27901 agattttctg tcgtgctagt tgtttgatct gttccttctt ctgtgacacc tacttcctga
    27961 ttcaatcctt gataaagcaa atcattgatt gggataaagt agcagttcgg catttttttt
    28021 gtcaccgttt ctgttccttt gttccaattg ttaacaattg tctgcatgtc agtgatctca
    28081 ggaaagttca aataaaatgg attgtagatg cctaaaatgt aaataggtgc ggttttattg
    28141 agggatcgaa attcttccaa tagttctgtg acattttcct gatagttttt cagtggcttt
    28201 ttaaaggaat tgaccgttaa cccgaataaa ttattttgga taactttcat caaatcatta
    28261 ccgccaacag tcagtgtgat aaaatcagct gttttgatat tgtttcgaat ttcttctttt
    28321 gtttttactc gctttaagat ctggtcactt cgttcaccat ttacaccata gttttctgtt
    28381 tcaaccgcgg tcaaattata acggtctttt agatcatttg cgacaagggg aacgaatcct
    28441 ccttgcttgg tttgatctcc tactccttca gtcagcgaat ctccgatagc tatgtagtga
    28501 agtttttctt ttttatttgg atcttctctc acagtagtta ctggtttcat tagtgggcca
    28561 gctttcggta tagaagcagc taaacctgca tagatgatga tcgcaattaa taatgggaac
    28621 aaaacgagga tcaaatgtcg tttcgttaat ttcatttttt cacctcttgt attcgattgg
    28681 ttctaatgtt atcaaaaatt ttatcaaaaa ggtagtcttt atgaaaaaag aaaacaatta
    28741 ttttcctaat tttataaaga aaaagagaat aagctgcaag cctttcaggc tgagggctta
    28801 tcctcttttc gactaatcta cataatacat gattgcaaac gcgtctttac cagtatgcgt
    28861 agcgataacc ggattcgtat gcagtacagg gatatgcatg tccgggaata attcttgcaa
    28921 accctctttg aattcttgcg ccaattcttt tgcatccgca tgtgaaatac cgatttgtcg
    28981 cacatttggc aattctttca gttcattttt caaattatta aaccatttat cgaacgtttt
    29041 ctttcctcgc cccttagtta cagggattaa ttcagaatgg gcgaaattca tcaccacgcg
    29101 tatgttcaaa acactagaca gcaaaccagt tgttcggctg attcttccac cttttaccaa
    29161 gttatctagt gtggatattc cgatgtataa ttttgtattg tcttgtactt ttttgacttc
    29221 ttcaaggatt ttctctactg ttttaccttc ttttgctaat tcagctgctc gaattacctg
    29281 aaaagataat ccttggtcag tggtatcact gtcgataacc gttactttcg tttttgttag
    29341 attactggct tgtcttgctg cttctactgt tccactcaag ccttttgtca tatggatcga
    29401 aatcacttca ctgccgtctt ctcctagctc atcatacatc gagatgaatt ctccaattgg
    29461 tggttggctt gttttgggca gattttttgc tttcgccatc atttccataa atctttcgcc
    29521 gtctagttgg tcatcatcgg gatatactgt tccgtcgatc atgatggata gcggcatgac
    29581 acgaatgcct aaagcatcgc gtacattttt ttccatcgta catgaagaat ctgttacgat
    29641 ttttacattt gtcattattt tctctctctc tttctttaac aagatgcctt attcatgtta
    29701 aactacatgt aagacaattt ctatttttag tataacagac aaataatgat ttttcattaa
    29761 ttacacctag taaaggagcc gttttcatgg aaaaaacgaa atttaatcga acgtatgaaa
    29821 tattaaatga agtgtttaat gcagtcaccc atggaattgg gactggattg agtatcgcgg
    29881 gactagtggt tcttttagta aaaggtgccc acttgcattc ctccctccat attgtctctt
    29941 atgctatcta tggatcgatg atgattcttt tatttttaac gtctactttg tttcattcat
    30001 tgatttttac aaaagcaaaa aaggtgttcc aagtattcga tcatagttcg atttttcttt
    30061 tgattgcagg aagttatact cctttttgtt tgctgagtat ccgaggatgg ctaggttgga
    30121 ctttatttgt attaatctgg ttgtttgcga ttcttggcat tatatataaa gcgttgacgt
    30181 tgcataaacg ggagagagta tcaaaagtat ctacgatcat ctatattttt atggggtggc
    30241 tctgtgtcgt ggctgctgtt cctctttatc actctcttgg aatgactggt gttattttga
    30301 tggtagcagg cgggctttct tacacgatag gcgcattctt ttatagcttg aattctatcc
    30361 gctatatgca tgttgtttgg catttgtttg ttatgttagg tgcaggtttt atgtacttct
    30421 ctgttttatt ctttacttaa taaaaaaaat aaagctatgg atgggacagc tctaaataac
    30481 agctagtcta tccatagctt ttttatatcg tcaattcgcc tgtcccgctt tttacaggat
    30541 tctcattacg ctgatacgtt tcaaattgat gcggataacg atttttttca tccatttctc
    30601 cttgactagt attgatcagt gaccaatcag accagtcaac aggtggaaaa taagcatctc
    30661 catcgaatac atgatggatg actgtacggt ataatatcgt acaaaatggc agaaattctt
    30721 gataaacagc tgaccctcca gcgatgaaaa agataccgtc tgtttctttt tccagagcaa
    30781 gcacgtcttc cacactatgc atgacatgca cgccttctgc tttataggaa gaatctctcg
    30841 tcaaaacaat cgtctgacga ttcggcaacg gacggctacc catcccttcg aatgtttttc
    30901 gtcccatcac tagtgtattt gcttctgtca tttgtttgaa gaatttcaga tcatttggca
    30961 aacgccaagg aagacggtct tcttttccaa tcaatccgtt ttcatcctgt gcccaaattg
    31021 cagctaacat tttctcatcc tttctgattc taaacagcga taggagcttt gatcgccgga
    31081 tgtgggtcat atccttctaa ttggatatct tccatctcaa aatcaaatac tgactgcttt
    31141 tcctgattca aaactaaagt cggaaatgcg cgtatttctc ggctcaattg ttctttcatt
    31201 tgttcgatat gattgatata aagatgagca tctcctaatg tgtgaacaaa ttcgccaacc
    31261 gctaaacctg tttcatgtgc aattaggtga gtcagcaacg cataacttgc aatgttgaac
    31321 ggaacgccta gaaacacatc cccactgcgt tgatacaatt ggcagcttag ccgtccctct
    31381 tgaacataaa attgaaacat cgtatgacaa ggaggcaaag ccatgctagg aacatcttcc
    31441 ggattccatg cagaaacgat caatcttcta gaatcaggag tctttttgat tgcttcgatc
    31501 acttgtttga tttgatcgat aaagccaccg tcttttgttt cccagtgacg ccattgatag
    31561 ccgtagatgt gtccaagatc gccgtatgtt tcagcaaagg aatcatcggt taggatcttc
    31621 tcgcaaaaaa gcttgctctg ctttttatat tcttcattga attcaggatc tgtcaaacat
    31681 ctatggccaa aatcagtcat atctggtcca ttatagtctg gacttttgat gtagcgttca
    31741 aatgcccatt catcccaaat atggttttta ttttgtaata gatagcggat attcgtatct
    31801 ccttttaaaa accaaagcaa ttcgcttttg atcaatccaa aaggtactcg tttcgttgtt
    31861 aacaaaggaa accctttttg cagatcaaac cgcatttggt atccgaataa gcttaatgtg
    31921 cctgtgcctg ttctgtcttc tttacgatgc ccttcttcca acaattttct tcctaagtca
    31981 agatacgctt gttccatcct ttttcctcct aatcttctac ccattcactc aagtattccc
    32041 accgtgccat tttttcttca agttgtgctt ctgtttcaga tacgtcgttt tgcaattctt
    32101 gtaatcgagt gaaattatct ccttgatgat tcatctcttc ttggagcaat gagatttttt
    32161 cttcaagttc tgcaatctca tcttcaatcg tttcccattc tttttgttcc atgtaagata
    32221 atttcttctt ttcagcaggt tccttgctct gtatttttgg tttcgctttt tcagcaggct
    32281 gctgggtctc tttttgcttc agtaaataac tggacatgtt tccgtaataa agttcttgtt
    32341 ttccgtttcc ttggaatact aataacttat ctgctacctt gtccaagaaa taacggtcat
    32401 gggaaacagt gatcacagca cctggaaaac ttctaaaata atcttccaaa atcgtcaatg
    32461 ttgctatgtc caaatcattg gtcggttcat ccaataataa aacattaggt tgctgaatca
    32521 gcagtttcaa caaaaataac cggcgttttt ctccgcctga aagtttgcct atcagtgtcc
    32581 catgcataaa tcttggaaat aaaaatcgtt caagtaattc tgctactccg atttgactgc
    32641 catctgctgt ttttgcttct tcagcagctt cttgtaagta agcaatcatc cgtttatctg
    32701 gtgccatttc ttcattttct tgtgtataat acgcaagatg aaccgtttca ccgatagaca
    32761 ttgtaccgct atccagggga attctgccag ctagaatatt aagcaatgtc gattttcccg
    32821 caccattttt accagtaata cctagtcttt cccgagattg aatcaataaa tctaaatgtt
    32881 ctagcagtgt ttggtcattt atacggtaac tgccatcttt gatttccagt acttttttcc
    32941 ctaaacgttg tgtcgctagg ttcagctcta aatcatcttc ttggtttact tggtacaagt
    33001 tctcctttag atcttcgaaa cggttgatcc gtgcttgctg cttggtgcca cgtgcctgta
    33061 cgccagccct catccaagct aattcctgtt tataaagccg cttgcgcttt tcttcttgtt
    33121 ctacttctac acgatcacgt tctgcttttt ctaagacgta agcttcataa tttcctttat
    33181 actcgtataa ttttccaaat gaaagttcga agattcggtt tgctactcta tctagaaaat
    33241 aacgatcgtg ggtaaccatc aatagtgcgc cacggtattg tttcaaatag ttttccaacc
    33301 actcgatcgc ttcataatct aaatggtttg ttggttcgtc tagtaatagt aaatcgggtt
    33361 catcaatcaa cacttgcgcc agactaactc gttttttctg accacctgat aaagtactga
    33421 tttttttatc taattcactg attcctaatt tttgcaaaat aatctttgcg ttggtatctg
    33481 tagtccaagc atcttcttta ttcatttgtt cttctgcttt agcataacgt ttttgcacat
    33541 cagggtcttc tccgttttcc cctagttcga tcaatgcttc ctcatatgct cgaacagttt
    33601 ggatcaaggg gctgtttcct tgaaagactg cttggagaac agttaattca tcggaaaatt
    33661 cagctgcttg agaaagataa ccaatacggt aatcagttgg ataaaacact gtttgccgat
    33721 caccgtcgct gctatcgata ccggcaataa tatttaagag acttgtttta cccgtcccgt
    33781 tcgtcccaat caacccgata cggtcttttt cgtggaccaa aaaagaaatc tggtcaaaca
    33841 aatctttttc accataagtt tttttgaggt cagttacttt taattctttc aacatgttcc
    33901 ctccttatct tggatattgt atcataaaaa tagtgaactt caggaaaatt tttttggtat
    33961 ttgttctttt tgtgttctca aaaaaagaac aggaccgatt cgatcctgtt ctgatatgtt
    34021 ttgtttttta taaaacttga aaatttttac ctttttattt tattggactc gttttttttg
    34081 actttgctcg aaacgcaaat cggaaagaaa agttatcaga tggtttgttc atcgtataag
    34141 attctaacaa attgatattc ctgcgatagc tgttcgcaga aaacgtcgtg attttttcag
    34201 caacttcgta ttcatcaatg atttttcttt caagataata acctcttagc atttttttcg
    34261 taaacagact atcttgctgg atcatccacg aagaaatcaa attccccgag ttcattttta
    34321 ttccttcaag tttgcgttgc tggataaaaa attgaaccat cgtttcatca taaatatcag
    34381 tcaagttatc taaactttca ataatcaact gagtattttt ttgatatgtc tctctgattt
    34441 cttggatatc ttcatcacta ataaatgtct gacgatcagc atatcttctt tgccaaaaca
    34501 ttttcggatg gagaacgatt cgcattaacc tacggacaac aatgaaccaa aagccgataa
    34561 aagacaaaat ctggcttgtg atagaatgtt cgaatcgaga aagaaaacgg gagtaaaaac
    34621 gataaccatt agaagaaagc ttgcccgaac gataactttc atccaatcca tcccgttcga
    34681 tcgacaaaat cagtgcttgt atttcttgta cttcttgctt ttcatcatcg gttaaatctt
    34741 ccaagtacag atcacgtatc cgttcttgat aattttctat cactgcttca gtggctaaaa
    34801 attcttttgt attacgatca atttccttta tttcttttcg caaaacttca acgacctctt
    34861 ctaaaatcat caaagcattc aaatccgtgc ttttcgcttc ctctgtttcc gtcagcatag
    34921 gcaagacaat gatccctatg accaaagtca ctaagatgac acccgccgtc agaaacaaaa
    34981 gcaaagaccg ctggtaaaac atcatattat tgattgaaaa tggcaaaata aaaatcgtag
    35041 ccaaactgac tgttcccttt acaccgccaa atgttaagat caagatctcg ttcaactgtt
    35101 ttttgaactt tttactgcca tctttgaata cataaaaaag actgatagaa atgaatctga
    35161 tcacaaaaag catgacagag attaatacga taatcgctaa taaaagaccg tttggatata
    35221 aaccgtctcc ccatactggc gagaacactt gcgtcaattc gattcctaaa aatataaata
    35281 ctaatgcatt cagtgtaaaa gcaatagttg tccatgtact gtgggacaag ctcgacaatt
    35341 ctgcatcaaa cacagagatt ttcctaaaac cagaagcttg gagaatacct gctgccactg
    35401 cagcaatgat tccagataca tcaaatgcct ctgccaatac ataggctaga aaaggaagca
    35461 aaagttcgat cagcagatac cctgtgacat cttgtgctga tgctttttcg atcaaatgaa
    35521 ttattttttg tttgaaccag acaagcaaaa agccgatcaa agctccccca atactagaaa
    35581 ctactagact catccccgcg tttactgctg aaaaagatcc ggtgatcagc gcaccaagag
    35641 caaactggaa ggcagtaaca ccagatgcat cattcaaaag accttctcct tccaaaatat
    35701 gcatcgcctt tttagggata ttcactcgtc cagaaagaga actgactgct accgcatctg
    35761 tcggacctaa cgctgctcca aaagcaaagc aggcagcaag tgggacactt ggcaacagga
    35821 atgataacgt cgcacctacc ccgacaaggg tcaaaatgac tcctccaaat gccaagaaca
    35881 aaattgtccc gaaatttttg agaatcgaag aaatatctgc tttttctcct tctctaaata
    35941 acaatggtgc aataatcata actaagaaca attcaggttc aaaatcgatt gattgtcccc
    36001 actctgtcag acctaatacc actccaagga aaatttggat cagtggagct ggaatcattg
    36061 gcaaaatgcg gctagctatg ttcgataagg tgatcgttac tgcaaataca ataactaact
    36121 cagcaaattc catcgtccat cccctttatt ttttattttg tgtaagcatt tttaaaaatt
    36181 gttctttttt ctttaaaatt ttggtttcga ctacttcaac ctgtgtttgg ttcccctcta
    36241 attcacactg tacacgtttt gactccaaac gaagcagatc atgtttcaga cgttccaact
    36301 gacgatacat caatatattt cttttacgca acttacaaag tatttgacgg cggtcatcca
    36361 tcgaaagggc gccatagcga tcatgcaaca gttttttttg ttgttcaaaa ctctctctca
    36421 ttttccagat ctcctataca caaacttcca tcattatagc aaagttcttt ttggatgaaa
    36481 aatatttcat tgtttcatcg tttattgcta gttagaaatt tccataaatt tttcaacgcc
    36541 tcattctatt ccaaatagta tcagatatca agtaaaactt aagaaagata aaagtttctg
    36601 acaaaaggat gtttactttc ccattcctgc ctttcttgtt cttttatcac aacaaaaaaa
    36661 tggggctgcg acaaaaatct tgtcacagtc ccttattctg aataaacggt gtggaagaga
    36721 cagcctatca gtagtaataa gacacatctc tttcacagcc tcatttttgc gtaaaaatcg
    36781 atttattcga aaaattcccc gtatacatct tctacacgtt gatctggatt gatcacgata
    36841 tacaagttac ctgttttttc gctgattttt gttgattgat attgattgtc taatccttct
    36901 gttcctttat ctagatatgg gaagtacaca agatcaggtg tgccatttcg gtaaaggatt
    36961 tccattcgct cgatatcttc gtatttcaat gcgcgattaa acatgcccat ttccagtccg
    37021 cctaggttga tatcatgtgt cgcaactgcg tccccttcat ggaagatttc gattttaaat
    37081 ccagcacacg gatggatttc aacaaattca ctgccattga ttcgtccaaa acttgttgtg
    37141 atttgtttga tccaaagatc gccgatatga cggcggttga tcgtccaggt ttctccattt
    37201 ctaaaataaa attttagcgc tgtcatttct ttactcatta aaaagactcc tttatgatgt
    37261 aatttattct tgtactacct cagtttagca caaatttatg taagtggtca catcttatgt
    37321 tttttcttct aatgacgtat ctgcccactt taagtagcca acaaagctga gcagatacag
    37381 tctagtgttt tttaaatcaa tttttctttc gataaaaaat ccaaaacctg ttttttatca
    37441 ttttttattc tttgttctac gacggctttt tcagctaatt gcaaagcttc actaacccac
    37501 ttaccaggtt tttttccagt ttcttctagc aagattttac catctactgc taattcgctt
    37561 aatgacttga taggtaaacg atcataggat tctcctacgg catccatctg aggtgtttcg
    37621 tcaaaataga tcatcaattc ttctacttgc agtgcatgtt ttttgcctaa gaagtacaat
    37681 tcgaatggtt ccaaagctcc agtttctcgt tgtcgtagtc cttggacaag tgcttgaacg
    37741 tctttaatca tttggttaga acacttccac gatttcaaaa aggaacgaat ctcattttct
    37801 tttagatcca gttggctgat caataatgcc catgcttggc tctcttcttt caatgggacg
    37861 gatggtaatt cagcaaaacg taaaagtgct tcgccttctt ctttcaaacc gggacagcaa
    37921 atgtagcact ctgtttcaat aaatgcatgg attcccgcgg cccgttcatt tcccaagagc
    37981 atcttgatga attccacatt tatacgttct acagatattt tacctaatag ctcgtggttt
    38041 tctttgatgg cgtagaaggt ttcttcctct aatttgaacc ctagttgact gacaaaacgc
    38101 aacccgcgca tcattcgtaa ggcatcttca tggaaccgct catgaggatt gcctacagct
    38161 cgcaagatct gttcttctag atcttgcaga ccatcgaaca aatcgatgat ttctccatct
    38221 tctttcaaag caaacgcatt gatcgtaaaa tctcttcttt tcaaatcttc tgccaacgaa
    38281 cgaacgaatt cgacatgatc tggtctacgg tagtcctgat aagttgattc cgtccgaaat
    38341 gtggtgatct catattgttc atcattttct aataccaaca cagttccatg ttcgatccca
    38401 atatctatcg tttttggaaa aagctgtttg atttcttctg gaaatgcgct tgttgcgata
    38461 tccacatcat ggattggctg gttcagcaag atatcacgaa cacttccacc tacaaaataa
    38521 gcttcatatc ctgcattctc taattttttc agaactggaa ttgccttttg gtattccaga
    38581 ggtaattgtt ttaatttcat ttttccaacc tttcctgcgt gtttcttgtc ctgagataaa
    38641 gactcagttg catggtgact gtttgacaag tccgtttcag agtcttcaag gccaggacca
    38701 cttcatcttg tttactcgtc cttacgctca aagcgattat ggtctctttg attgaatttt
    38761 tccatgtttt tttcaaaaac ttcagttaag tcgatattca atgaattagc catgatcatc
    38821 gtaacgaata aaacatcacc aagttcttct gctaccgagt taactggttc agaagccttt
    38881 ttgctttttt ctccataagt gtggttgact tctcttgcca attcacctac ttcttcagtt
    38941 aatcgagcca tctgagctaa tggagagaaa taccccacct tgaattgctg gatatattca
    39001 tccacttcct gctgcatact gtataaagaa cgctttttat ccatcttttt ccctccaaaa
    39061 ctatcttacc aaaactttaa cgcaaatcct agataagagc aattgagaaa atcgaatttc
    39121 catgctacat ttaggaagga atttctaaat ggaaattctg tgaaaataca taattgaaag
    39181 ctggaattca tatggtcaaa cgaaaaacag taaaagaagt tctttttatc attataggaa
    39241 caagtattta tgcatttggt cttgtttact tgaacatcgc taatcattta gcagaagggg
    39301 gagtctcagg gatcaccttg atcttaagag ctttatttgg tattgatcca gcttatacga
    39361 ctttattaat caacatccca ttgattttac taggaggaaa gatcctcggt aaacgttcct
    39421 tggcctatac tgttctaggt acactttctt tgtcattctt tttatggatc tggcaaaggg
    39481 ttccactaga aatcaattta cagcatgatc tactgatcgt ttctctactt gcgggtttag
    39541 ttgcaggtgt aggaagcggg atcgtctacc gcatgggtgg aacaacaggc ggcagtgata
    39601 ttatcgctcg gattttagaa caaaattacg gcatcactat ggggcgttcc ctattggcat
    39661 ttgatatcat cgtcttactt gcttcattaa cctatatcga cttgaaacgt atgatgtata
    39721 cgttgattgt ttcgtatgtt ttcagtcgtg tgattgattc gatcttagat ggcggatatt
    39781 ctgcaaaagg tctacttgtc gtctccaaca aaagcgaaga gattgcacca ctactgatga
    39841 ccggtctgca aagaggtgtg actttccttt ctggagaagg cgcattctct ggtaattcaa
    39901 aaaaaatcat ctatatggtc gttagctcta gtgaattaac tgaagctaag aggatcgtcc
    39961 acgagattga cgaaaaagct ttcctttcaa tcatcaatgt gcatgaagtg gaagggcaag
    40021 gctttactta tttgaagcca cagacaagat tactgaaaaa actataagaa aaaagacaaa
    40081 gataggctat gaggaaagat tccacatcca gctgaccttt gtctttttta gtactatact
    40141 atttttaact aattgttatg ttcacttacc cggttacttt tcttttgtgt ctgcaaaagg
    40201 atctttcggt taacttcatc agataatttc aaaaaagcat ccctatctcc atcttctagt
    40261 gcttgatcga tttgagcata aagcattttt agttttgcct cttcttcttt ttcttgaaaa
    40321 tatcgttcaa ttaattcagt atcttcttca ctgactgaag aatcccaaga agaaaatgga
    40381 ttgtcttcta agatagatag atattctctt gtctgccaag cattttcgaa tatacattcc
    40441 acatataaag gctttttcca attcaaacgg atttcatgaa aaatctggtc tgtgtccgta
    40501 aattcttttc cctgcaaaaa caatttcatg ggttcccctt caacagatag atcactgatc
    40561 tgcagtcctc gatccgcaaa attcgcccct tcaacaaagt ggacattgct taaaatcgct
    40621 tcatgattgg caagataatt caagatccaa aaaacttctc ttcggctaaa agatacatga
    40681 ttgaccatcc acgttaaaaa attcttcttt tcccgtacat caattagcat ttttctcacc
    40741 tctctgttag gtcatctaat aatgacagtg cctccatatc tcctggttca agtgttaaat
    40801 aataagtcaa taattcttgc gctcttttca gctgcccttc ttctcttaag aaaaaggcat
    40861 actctttcaa gaaatctggt tcatgtgata gttcatgata agcctgttca tagtgtacag
    40921 ctgcaacggt aaagtcttct aattcattat aagcatgggc taggttccat tctgcataag
    40981 gattagcagt ttcttccatc tgattgatca cttgtatcac atcttcatat ctttcatcat
    41041 ccaagtaaag attacttaaa gtaagtaatg tttcatcttg tttgtctcct acttctaaag
    41101 ctttcagtaa aagttcttct gctcgctgtc tatcatgcag acggaaagca ttttccgagg
    41161 ccaggtgata aagttcgact tggtaaggat tttctttgat tccttcttct aacactgttt
    41221 gtgcttcttc aatcatttct tcttcttgaa gagcttgtcc tagatataga tataacgatt
    41281 gataatgcgg attaacttct cgaagttctt ccagatagtt gattgcctgc tgattttctt
    41341 tcaattgaag attcgtaaaa gctagctgga acagtcgatc atctgtcctt tcttctttca
    41401 gtgcttcttc taaaggtacg atagctgctt cgaattctcc ttgcatactt aaggattgtc
    41461 ctaaacgttc ctgcatcgag attcctgaaa tttcatttat cccgcttgcc aacaatgttt
    41521 cataaaccac tgctgcctct ttgaaacgat caactgaaaa atacaattca gctagcgcaa
    41581 actggatcaa tggttcatca ggaagcaacc cagctgcttc tttcaatttt gcttcactca
    41641 cttcagggat tccgataact tggtacaaat cagctatcgc caataagctt tgcggatagt
    41701 aatcactttg cttatccact ttttccaggt attcaaaagc taagtcgatc tcattatctt
    41761 cgattgcaat ttctgctaac gggatgttca gtccgtcatt ttctgggtat tggttgatca
    41821 gttgttcaaa aatctgtttt gcttcgatca aaaagccaat agccagcaat tcttcgccta
    41881 gttcagctaa tatatctgct gggtcttctt ttaatgcttt ttctaaaaag atttgtgctt
    41941 gtgacaagtc ttcatctgat aaagcttgca acattttttc gctatttgta ttcatttcaa
    42001 ttccctctta tctcactgac gatttgttga aataccgtca ttgttctcaa taattctttt
    42061 tcgtttggat gttggtatcc gtctattata cctatttttt ctaaaacaag tatttttttg
    42121 cttttttctg ccaaaaaaag aactttttcc aaatactcca tctttgaaat ctgttccagc
    42181 cagtggattg gatagccaag caagtccagc cacacaaaaa agttttttag ttggaaatca
    42241 aaaggatatg cttggagatt ccacacgaaa tgaaacatca ttcctaaaaa ttttttcata
    42301 ctagcagaaa gtagatggcc attttcggtc agataaaaag cttgttcaaa cagtttacca
    42361 taatttgaca ggttttctgc ctctaattga taaaaataga tcatttcttc gatcatcccg
    42421 gcaaacggcc gagtcgttaa ttgcttttta tttggatagt ttttatacag attttgcaaa
    42481 aaacgatgat cacaaatcat tccgcaacag ataaaagtca aaaagtcaat ctgctttccg
    42541 tccacctgcc gctcgctgat tgtttgatca taaacgatgc gttctggcag attgatggtt
    42601 tgcagcacta cacgatttgg tagctgcaaa atcgtccgct gcggtgttaa tgctcggctt
    42661 agagaacgga tcgatacagg gatcatccat agtgatgaat caagggttgt atgtttttga
    42721 aaaaaacctg ccagatccat gatcccttca tttccaaatc cgatgataaa catggattga
    42781 ttttcgggat agcgtttgac gaaatcaagc aggttcttta attctgttaa atgattgcat
    42841 tgagtgttgg cacaaatata ccagtcattg tttgcttgat ttgcaaataa cgggttgatc
    42901 ttatctgcaa acaaatcata atagcgctga ttcgttaaaa ataagattgg ctgatcaatg
    42961 gaaagttctc ttagctgact gactagcgtt tctccgtaaa acactttcgt caacgcatct
    43021 tctacttgat aatcaagttc catacgcatc cctcctcttc ttatttttat tttaccatta
    43081 gtaagcaaat tctagaaaag ataagagcaa agctcacctc ataacttgca aataaataaa
    43141 aattaaataa aatacatgtg ttttctatgt atgacatacg gattcggaat ctctgtctct
    43201 tatttattcc ttttctgcta ggaaataaaa agaaaagcac ttgtagccct agagccacaa
    43261 gcgctttttc aactgtctta tttaacagcg tcttttaatg ctttacctgg tttgaatgca
    43321 ggtactttgc tagctggaat ttcgatttct tcaccagttt gtgggttacg acctttgcga
    43381 gctgcgcgtt cgcgaacttc aaagttacca aaaccgatta attgaacttt ttcgccgtta
    43441 gctaaagcat cttgaatagt tgaaaataca gcatctactg ctgcagttgc atctttttta
    43501 gttaaatcag tagctgaagc aactttttcg attaattctg ctttgtttgc catggataga
    43561 ttcacctcct ccacaagaga tatgatagaa atatcattta gttaaaactt tctgagtggt
    43621 ccagaagttt aaaaagaaat attgattaac ttcaatattc tgttatcacg atatcatatg
    43681 aaccgcttaa tagcaaggtt tttaccaatt ttcacatgct ttttttagtc atagaaacgt
    43741 aacaaacgaa actgtctttt tcttttgaaa aaaaaacgtc gatatggtaa aatgcctatt
    43801 ttctcctacg agggataatt cggatggacg tcccttcaaa agtaaatgct tttctgattt
    43861 gattttctaa gaaacgttca taagaaaaat gcatcaattc ctcttcattg acaaaaacga
    43921 caaatgtagg tggtttgaca gcgacttgtg tagcataaaa aatcttcagg cgttttcctt
    43981 tatctgttgg tgttggattg attgctacag catccataat gatatcattc aacacagccg
    44041 aagagatacg aagattctgg ttcatactta cttgttcgat catttcaggc agacgttcca
    44101 accgttgttt agtcactgca gaaacaaaaa cgattggagc gtaatcaaga taccggaatt
    44161 catcacgaat ctcttgttcg aaatcacgca ttgtattggt ttctttcttt acaagatccc
    44221 atttattcac gacgataata attccacgac cagcttcatg ggcgtaaccc gctactcgct
    44281 tgtcttgttc ccgaatccct tcttcagcat tcagtaccat caaaacgata tcagaacggt
    44341 caatggcacg cattgcacgc atcacgctgt atttttcagt attttcgtat acttttccgc
    44401 gtttacgcat accagctgta tctatcatta agaatttctg accactttca gaaacgaagt
    44461 gggtgtcgat tgcgtctcgg gtcgttcctt caatatccga aacaattaca cgttcttctc
    44521 ctaaaatcgc attgatcaaa gaggatttac caacatttgg gcgaccaatc aaactaaact
    44581 taatcgtgtc gtcgtcctct tcttcagtct cttcagagaa atacttcact gcttcatcta
    44641 aaatatcacc aatccctagt ccatggcttc ctgaaacagg ataaggatcg cctagcccta
    44701 aggaataaaa ttcatagata tcgtttctca tttctggatt atctacttta ttgactgcta
    44761 aaatcactgg tttattactt ctgtataaaa ttttcgcaac catctcatct gcgtctgtca
    44821 cgccttcgcg tccgctgact acacaaatga ttacatctgc ttcttcaatc gcgatttctg
    44881 cttgatgctt gatctgatcc ataaaaggtt catcgccaag atcaattccg cctgtgtcga
    44941 tcacgctgaa ttctcgacct aaccattcac cttttgcata aatacgatca cgagttactc
    45001 caggagtatc ttcgacaatc gagatacgct caccagcgat gcggttaaaa atcgtagact
    45061 taccgacgtt cgggcggcca acgattgcaa ttgttggatt tgccatatta tttcctcctc
    45121 acaagtttcc aatctcactt agtttaacga atgcattgcc aactttcaag catagattgt
    45181 caattaaacg aagtattttt attccttatt gaaatactaa tcgcttttca aaagaaaaac
    45241 tgagacaaaa gcagctgctt tcatctcagt cacagataca aaatcaatta tttttcagaa
    45301 tcatcggttg ctttttcttc tacttcttct ttcaacgcat cacctaaaat gtctcccata
    45361 gtaaatccag tattttcttc tggtaattca taagactcaa cattttttgg ttcttcttct
    45421 gaagctggtt tttcttctaa agctttgata ctcaatgcaa tacgatgttc ttctggatgg
    45481 atctctaata ctttcacttt cacttcgtca ccttcatgaa gcacttcatg tggtgtcgca
    45541 atatgtttat gtgaaatttg agagatatgg actagccctt ctactccagg gaacacttca
    45601 acaaaggcac cgaagcttgt caaacgttta actgttccgt ctaatactgt gccaactgga
    45661 gcttttgtat cgatttctga ccaaggtcca ggctgtgtgt ctttgattga caaggaaaca
    45721 cgttcttgtt caggattgat agacaacact ttgacattta catcatcatt gacagccaat
    45781 acatcacttg gttttgctac atgactatgt gaaatctctg agacatggac tagaccgtca
    45841 attccgccta ggtcgacaaa tgcgccaaaa tcagtaagac gtgcaacacg tccactgaga
    45901 acatctccct catggatagt tgaaagaatt tcttttttct tttcttctct ttcgttttcc
    45961 actaccgctt tatgcgataa gatcaaacga ttttctgatg gttcgatttc gatgatttta
    46021 aagctcaatg ttttgccttt atagtctgaa aagtctgcaa caaaatgatc ttccaccatt
    46081 gatgcaggga caaaaccacg tacaccgacg tcaacgacta aaccgccttt gacaacattt
    46141 gtaacaggtg cttcgatgac cttgccctct tggaaatctc tttcgatatc ttcccaaact
    46201 tttttagcat ctaaacggcg ttttgaaagt agatagctgc cgttttcttt atctttgccg
    46261 atcgtactga taacgactaa atctaataca tcaccgactt ttactacttc gctgatatct
    46321 tctaccggca aagttgataa ttcttttgcc ggaacgactc cttcaactcc agccccttcg
    46381 attccgacaa tcacttgttt gtcttcaatg actaaaactt cgcccttaac aacatcgcca
    46441 acttttactt cttgtacgct tttcattgcg tcttccattg actggttgtt ctcttgattt
    46501 tgatcaaatt ctgtcataac acttgtcctc ctaaccaaca ttctgccgta agtacggtac
    46561 tgtttttagt ttaattgatt attcaaaaaa aataaagcga tttcgttcgt tttccttgaa
    46621 aaaacaattg tttttcattt tttttcttaa tttaaaaaag aagataacct tttttcaaaa
    46681 caacagcttt tattgctgca acgacttctg gaatcgattt gccagtcgta tcgatacgaa
    46741 cagcatcctc tgcttgcttc agcggagaga cgtcccttgt tgaatcataa tggtctcttt
    46801 cctgtatctc tttcgtcagt gtttcaagat cagtcggaat tcctttttct tggttctctt
    46861 tgaaacgtct ttctgcacgc tcacttacgc ttgctactaa aaagattttc acttctgcat
    46921 tcggtaatac agctgtcccg atgtctcttc cgtccatgac aacgccaccg cgttccccta
    46981 tttttcgttg gacagcaact aattcttctc tgacttttcc atgtgcagag acttcagaaa
    47041 cagcttttgt gacatctggt tgacggattt ctaaagtcac atcttttgat gctatgaata
    47101 catgctgtcc atcttcttgt tgcgaaaaag agataggata ctttttgatc agcgaaacta
    47161 gcccttcttc atctgaaaaa gatacattgt tcgtaatagc taaataagtt actgcgcgat
    47221 acatggcacc ggtatctgta taaatataat tcaattcttt tgctaatatc ttggcaacgg
    47281 tacttttccc agatgaagca ggcccgtcga ttgcaatact gatttgtgtc atgatataac
    47341 tcctttttct cagaaaaaaa gccgcaaagc gcggctatta ttatttaatt cttaattctt
    47401 gaccagggta aagcataaag ttgtttggat ctaagccatt caattcaaac aattgatcag
    47461 tggtgatccc tgcacgctca gccacttgtt ttggaccttc gcctgcttga acagtcgttg
    47521 ttgaaccggc tgcagctgat gaagaaggtg ttgtttctgc tgcattgctg cttgaatccc
    47581 ctgcttgata agttgcctca cttgaggaag tcggtgttgt ctctgctgca atactgcttt
    47641 ctgacgttac acctgtatct tgagacacag tagattcttc cgcgattgta ctagattcta
    47701 ctgttgaagt ctcagttgac tcctcttttg ttgtacttgt agaactttct actactgatg
    47761 tcgaagtttc agaagaagtt gctgctgttg cattgttgct tgatccattt ctgatccaga
    47821 aataagcacc tgctggaata gcgatacata agaccagtaa aatcaaaaat agcgaaagaa
    47881 ataatgtatt tcctttcttt tgttgtctct gagaacttct tgatgaaact tcatcatctg
    47941 tatcgtagat tggttgttcc catggttctt gtgtttcgtt attttctgta gattgatgtc
    48001 tatcttttct gctcactgtt ttacctccta aactctatcg tgtgtattat accataggaa
    48061 aaagtgtctt gtcctaaaaa atcaatgttc catgtttttt ttaaataaat ttagtaaaat
    48121 cgtttcccaa tgaagttgtt cagtcttaga aaaaagcttc ctctttggca gaagttctgc
    48181 ttttgctcca tcaatatcac aacaattctg cggcttttcg gagagttttt cgccaaaata
    48241 agctaagatg aattttctgc ggcagttttc ttcattaata tagcgaagca tctgctgcag
    48301 gcggaattct ttttcttttt cctgacgttt gagccgttcc acccaatttt ctggtttttc
    48361 agactgctgg atcagctcca tccatttttt ttgcagctca tcaaagggag cttgctttgt
    48421 ggcatattcc aaataaagct caaaactttg tcgctgttct ctagaaagtt gattaaagaa
    48481 ataatggata cgttcatccc cactttgata aaaaagaatt gctgcacttt cttcctgatc
    48541 tctgcctgct cgaccgattt cttgtacata gttttctaga ctgtctggca aatcataatg
    48601 gaccacataa cggatatcag atttatcgat ccccatacca aatgcattcg tagcaatgag
    48661 aaactgcagc tgatttttta caaactgctg ttgaagttgt cttctttgag ctgcatcaag
    48721 accaccgtga tagtatccaa ctgtaaaacg ttccctgaat aaatgataca atcgttcgac
    48781 ttcttttttt gttgcacaat aaatgattgc cgctccttgt gctctttcca tgaagtgttc
    48841 aagttcttgt tctttttgct gcgttttccg aacaaaaagc gagatatttt gccgattgac
    48901 tgattgtctg atctcttttg gtggtcgatc aaatagtaca tgacgtatat ctcttgctac
    48961 taaatctgtt gctgtcgccg ttagtgccag tgtgaccggg tttcctaaaa gctttcggat
    49021 ttttcctaac tgttgatatt ctggacggaa atcaactccc cattgagaca cgcaatgagc
    49081 ctcatctact acatataacg caatattttg ttttttcaga tgctctaaaa gagaaggatt
    49141 agtcaacatt tcgggactca aaaacaaaaa tttatattgc gatagatgac ggaggacgta
    49201 tcttctttca gattgcgaaa gtaaactatt gaaagcagct actcgtttct cccctcgttt
    49261 ttgtaattgc gtcacttgat cttccattag agaaagcagc ggtgacacga tgatgaccag
    49321 accttccatt aaataccccg tcaattgata gcaaaggctt tttcccgttc ctgtaggcaa
    49381 aatagcgaga gtatcttctc catcaagcaa cgcctgaata atttcttctt ggccgggacg
    49441 aaatgaatca aatccaaaat atttttttaa ttcatttatt aacattctgt atcgcttcct
    49501 ttctcaatag atagatttga tacaaacgaa attctccata atctaattgt ccatctacat
    49561 tccattcgct aaagcgccac tctcgcacgg aatccttatt tggttccaaa cgttcgattg
    49621 tttctgcaga gagaatccac tcgtatggaa aatcatcaaa aaacaaggcc cactcaataa
    49681 gatgatctgt tactgttcct ctttttaaat gacggattgc catgatctgg tcaattgtct
    49741 gaccattcat aaacatctgc ttggtgatca tcatgctttg attgaaattt tgctgtaata
    49801 atgaatcgat caaagcgtgc caaagcgaat ctggccgttt ttcgatttgt gctaacaaaa
    49861 ggtggataca tctgctttgt tgcagataaa cctctgactc atcattgttt tttgccagct
    49921 gataaggaag cagccctgtt cgctcatttc cagataattg gttagctaaa aaatctgctg
    49981 cttcttctgg tatctccgaa aacagctgca ccaaactctc atacgcagta tcaattaaaa
    50041 tttcacgtgg caattggctt tcactaagcc atttttttag ttggaaagta taaaaaggac
    50101 ttgtctctgc tggaagatag tcttgaatac ccgttgccag attagaaatt acttgaacag
    50161 caaatttaat gagccgccaa ctagtttccc ctgttctgcc atagcggtca aaacgcaaac
    50221 cagtatgttc tatttgatgt tcggacaaca tatcagcccc tgcaggcgtt agctttgctt
    50281 cattttcatt tatttcgatc caaccttgct gcgcaatttt ttgcaaaatt tgataaaact
    50341 tatcctgctt caattctgga aaactgttat ggataaacaa aagttcgtgg gtaaatccat
    50401 aaataagtac tgaagtcgtt cgttttccca caaggagttg gtaaagagaa ctaatccgca
    50461 gcttgtgtcc tgatgaaaat agcgataaaa taaaaacaat catattattc tccttaagtt
    50521 aggatggtta gaaatgtcac tactatgtaa acttgtacct gaacgctgta ttgcatgcgg
    50581 tctttgtcaa atcgaagcgc cagatatttt cgattatgat gaagaaggaa tcgttttatt
    50641 tgcccaagaa ccagaggctc atcaacagtt cgtgatgccg gaagaagaaa catatgtaaa
    50701 aaaagcgtat caaaaatgtc cagttcgagc gattttatta gaaaataaaa tataaatata
    50761 aacgaaactt taaaaacgta cactaagttc tctaaacttg aaaataagcc gggatctgtt
    50821 tctcttgttc cgtgaaatcc cgacttattt tgaaagattc atttgctatc tatagttaat
    50881 tgactagttt tttcacggac cctataggac ccatttatat tatttcaact ttttcagcca
    50941 gttttccaat gtattgacga tcacagtttg ctggtctgcg ttagaaattt ctgcctctcc
    51001 atctcctttt tgctcaccat agctgccaaa acctccatga tttccgccat tgattgatac
    51061 atactctgtt ctttccggta aatactgctt agcttcttga taagcttcct gattcaatac
    51121 tttatctttt gtcgccgtga tcgataaaac aggaacagct gattctgtca atgttccttt
    51181 tttgtcggga taacttgcca tgaagaatac cccttttaaa tgtttgtctg aatgattctt
    51241 attgacataa cgacttgcca ttacgccacc taatgaatgg ccaccgatca cataatcgga
    51301 atttggaaaa tcttctttga ccttatccgc tttgtttccg cccatcactg ctagatcaag
    51361 tggcattttg acaatagcga ctgaaaagcc gttttttgct aaatcttgcg cccaaatact
    51421 ataactttct ggctctacga gagcaccagg ataaaaaata agtaatggag actttccatg
    51481 attctttttc tctccttcaa aaaataagta atcttctttg ttttttcctt cttttaccaa
    51541 cacttgcgct tctgacgatg gttcgtacgt attttgctgt atatagtaat aaccggctcc
    51601 accgagtaat cctaaaatga tgactaagcc aattagtatt cgtctaaata ttttcacttt
    51661 ctcccacctt ttctatctga gtgacccctt tttcttaatc aagtatgatt ataccttaaa
    51721 aaaataagag agaaatgcaa actttccagc atcaaataaa aaaagacgga atatccattt
    51781 gaatatccgc cctttttgta tgtttatttt tatttagcac ataaacgata cacagcttct
    51841 gcataaattt ccattgcttt atacatacta cttaattccc atcgttcatt cgcctggtgc
    51901 ataaagtcag gagtatcagg gaacatcgca ccgaatgcca cacactggtt catcgtacga
    51961 gcaaaagtag cgccgcctga tacaaacggt tcagtcatgt ctccagtaat atcgcgatat
    52021 gtccccaata gatttttcac taactcactg tctagtggca cgtataatga atcaaggaag
    52081 tcaaattctt cataagtcaa cccatatttt tctgctgttt tagttaattt agctactaaa
    52141 tcatctttct tgaatgtaac agggattctc atatctacac cgatttttgt ttgttctggt
    52201 gtgatttcca aacttgcaaa gttcatcgtt agctcgccgg attgttcatc ttctgttttg
    52261 cccacgacag cttcaccagt tgcattttct tgaactaatt ttcctaagaa attgattggg
    52321 ccaaaatcaa atacttctga aagagcaatt gccagacgag aaatagcatt cactccttgt
    52381 gctgcatctt tcgcgtggat acttttacca agaacgacga tgccttcacc ttgttcttcg
    52441 aaatcgaatt cgtgtttttt caatgcttct tttacttcag aaagcttttc tccagagtaa
    52501 ggagctgcat caggaacaac attcaacgct cctccagctt ttacagaaaa ctcgttcgtt
    52561 cctggtcctg tcaagtaagc ttgcaataag cctttttctg cataaattaa aggaaattca
    52621 gcatctggcg caaatccttg cgtaattcct tcttcttttt cgttatattt ttctaaacaa
    52681 cgccataaat tttcttcatc tgtaccaaag ataaaacgaa tacgtgtctt gaattccacg
    52741 ccagcatcaa tcaaagcttt gacggcatac attgccgcaa tagaaggacc tttgtcatct
    52801 tgggatccgc gaccaactaa ccagccgtct tttatagttg gatcgaatgg ttttgtttcc
    52861 caattatttt cgtcccctgc tggaacaacg tccatatgac acaagatacc gaataattca
    52921 tctccagagc caatctctga ataaccgtaa tagccttctg gatctttaaa tgttctaaat
    52981 cctagctttt cactgatttc caatacttta tccaaagctt caatcacttt tttaccgaag
    53041 ggatgtcctt gtcctgaatc tgcttcatct agtacggaag gaattcggat caattcgctc
    53101 aatgattcta atgcttgttc atgatgttgt tctgtcacaa attttttcat gatattatcc
    53161 tcctaatatg ttaaaaaggg tcatgtcaaa ttcctccgac acaacctctt cttctcaaat
    53221 aatgacgttt taagcctgct ccatcagcaa gcagaatgtt cttaacaaat gatgaaagaa
    53281 aaaacactca ctgaatggag ctattgactt atccacgtgc ttatcgatag ccgtttatcg
    53341 gtttcttcat tcttatgata gaccttgtac ctgtatttgt ctaggtttag aacattgctg
    53401 ctacacctag gatcacacag atggctacaa ataatatcgc aattaattta ccggtaaatt
    53461 tccaccacac tgaaacatcg aaacgagcaa ttgctacagc acccattacg atagcagatg
    53521 ttggtgtaat taagtttact aaaccagatg cagattgata agcagtgatt actaaatcct
    53581 taccgacgcc ggcaaattca cccataggtc ccatgattcc cattgttgca gcagctaagc
    53641 cggaagttga aggaatcaag aatgacatag ggatatagaa aataaatgta ataatgatga
    53701 atacacttga agataatgaa cttaatcctt gttcgcccca atgtaagatg gtgtctgtga
    53761 ttaatccatt gttcataacc acttggatac cacgagcaac agctactacg attgctacac
    53821 cgatcaaatc agaagcacca gctaaaaatt cagagacaaa ttcagactct ttcatgccat
    53881 aagtgattgc tactacgatg gacattacta agaataacat agtaatttct gggaagtacc
    53941 agtcacctaa tggaagcatg cttttaccta gaaccgtacc tagtaccgga aggtttgtta
    54001 accagtttgt caatgattca aaaatcgtga aattcgcatt caaggttgtc caaggaatca
    54061 aactgatgat catgatacca aaagtaataa agaacaatac attaacatgt ttttgttttt
    54121 tcgtgattac ttcttgacga ccgattgctt caatatcgaa atgcttcata tcttctttac
    54181 gttggttgta tactaatgat tttgttggat ctttttcgat ctttgatgca taacgataca
    54241 catatacaat agaaatagct aacaaaataa cgaacatcaa gaatcgaaga ccaatacctt
    54301 cacccatcga aatcccaaca gcttgtgaag ctacgcctgt tgcaaaagga tttaccgttg
    54361 aagctagaca gcctacttga gaccctacta atacgattgc tacagctact actgtatcaa
    54421 agcctacagc catcatgact gggatcagta aagcatagaa tggaatcgtt tcttctgcca
    54481 ttccgtaagt agagccgcct aatgcaaata acagcatcaa tactggaata agcatttttt
    54541 cttttccttt gaatttcttc acaactgaag caatcccggc atctagtgcc cctgttttgt
    54601 tgataatacc taaaaatcca ccaacaacca aaatgaagaa agagattggg attgcagcag
    54661 gtgtttcttt agttagctcc cccgctggta cacctagcat cccattgatt ggcgccatga
    54721 aaatatccca cagcccttga ggattttgtt gtactcgttc atatgatcca gcgacgatgt
    54781 tgcctgcatc gtctacacta tagtgcccag ctggtataaa ccaagtaagt acagcgatta
    54841 ctgcaataat aataaataag accgtatacg ctgaaggcat ttgaaatttt ttcttttttg
    54901 tttgttccat cttcttcttc ctttcttttc cgttagagac aacaattttg gctctaatgt
    54961 tattttatca aaaagagtat cagaacaaaa ataataacac gcattttgta aaacttttgt
    55021 tcaaaaagtt cgtttttccc tattccctcc tcttttttca ggtttttaaa gctttcttct
    55081 ttttcattgt agcgtttcct tttttttata aacaaacatt ttcgtctttt aaaaggagaa
    55141 gaatttcaca tttgcaaaga attgattgat ttttatgcat aaatcaaaaa aatactcaaa
    55201 acaaacaaat aaaacgttta cattattgca tgtcttgtat ttttttccaa aaaaaaaaga
    55261 ccaagaaatt tcttgatctt tttgatattt atttgactgc tgtatgacgt tgttcgaact
    55321 gatgttgttt tcgacttaac catggaagaa gttgcgcatg cagcactaaa aagacagcac
    55381 tcacgatgaa tcctttgatc aagttgaaag gaacgatccc aatcagtaca tagtttgcta
    55441 aagacatgcc cagcatctgt gttgcgttca gccctaaaaa cattaagtaa agaggcgtaa
    55501 taacgaaata atttgcgata ctcataaaaa tagttagagc gatggttcct gtaatgacac
    55561 ctaaaaattt gtttcttcct ttatgctgtt tctttacact aaagaaataa taaatcggga
    55621 atgtaaagat cgttgttgat aagaaactag cagtgtctcc taccaaatta tccggagaaa
    55681 aacctgtagt cagcagatgt aatactgaac gcaagaacgc tgttgcaact ccggccgctg
    55741 gaccgaataa gaacatgctg atcaataccg agatatcact aaaatcgatc ttcaaaaaac
    55801 taaaagccgg catgatcgga aaagcaaaat actgtaaaac taatgcgatc gcagcaaaca
    55861 tcgctactgc aaccattttc tgtacacggg tgttcttcat ttgaaatcct cctgttagga
    55921 ctcctcttca gcgaactttt tgacgtttct ctccaaatga aaaaactcta ttttccaggg
    55981 aaaatagagt tagagttatt tgatcaagcg tcgtcaaata agctctatct tctttatcca
    56041 gactatactg tcggtatcgg aatttcaccg attcagctat ttttttgcaa aataggtcgt
    56101 ggactataac caccggtcgg gaatttcacc ctgcccctga agacgaacct tatataattt
    56161 ttgtttacat attcattata catatctatt caaaaaacgc aacatctaac acttataaaa
    56221 agtaagtgtt cattttgagt ggttcagcaa actgctgact tcttttttgt tcagttcacg
    56281 gtaatcccca ggacgtaggc cttgtaaagt cagatctccg tatttttcac gttttagttt
    56341 ttgcacagga agaccaactg cttgaagcat atttttcact tgatgattac gtccttcgtg
    56401 gatcgtcaat tccacgatac tgtggtttgt cttaggatcc actgataaaa tttggaattt
    56461 agctggagat gtttttcgtc cttcgatctt tattcctttt gtcaaaggtg caagcatcga
    56521 ttttgtagcg atccctttta cctttgcaac gtaaacttta tccacttcat gttttggatg
    56581 tgtcaggcgc tgagcaaaat ctccatcatt tgtcagtagc aagatccccg aagtatcgta
    56641 atccagtcga cctacaggat agatacgttc ttttaccatc ggcaaaagat ccgtaacaac
    56701 ttttcttcct ttgtcatctg caacagcaga aataactcct ttaggtttgt acaataaata
    56761 gtaaccgtat tcttcttgat aaattgggac ttcatccact tccacagtgt catgtttccc
    56821 aacttttatc cctaattccc ttacaacttg tccgtttact tttacacgtc ctgcaaggat
    56881 gaattcttct gcttttcgac gagaagtgat gccagcgtgg gcaattactt tctgcaatct
    56941 ctccattaca attattctcc tttattcatt ccatcaaaga atagatctgg tgacacgtct
    57001 tcttcaagtg aaatttccat ttcttgtgta tcaggcagtt cttctaatga tttcaaacca
    57061 aaataatcta agaagtagcc agttgttcca tataatatcg gccgacctgg tccttctact
    57121 ctaccttttt cttcaatcag tttatgggca gctagacgct gtaccgctcc tgaaacctga
    57181 actcctcgaa tctgctcgat ttcagctctt gtgattggct gtttataagc gatgattgct
    57241 aaggtttcga cggcggcttg agataatgtg tttgatgtcc cttgcgcata tcgcttaagt
    57301 aagggagcca gctctttttt agtcgttaat acataatggc tttccgtttc aaaaatatgc
    57361 aaagctgagt gcgagttttg agtgtaagat tcttttaatt ctttcactaa acttgtgact
    57421 tctgcttcgc tgagatttaa cagtccgctt aattcttcat tactgatccc ttcctcgcca
    57481 acaataaaaa gaagggcttc aagttcactt aatttcgtca tgttcggtat ctcctactgc
    57541 tggataaagc ataattgatt catagttttc tttttgttgc gcaatgatct gccctttttt
    57601 catcaattct agcaaagcca taaaagtagt gacaacttca cttttagaag gtgactcaaa
    57661 aaaagaatcg aaagtacagc catgcgcatt tctttttata cgctcttcga taaataccat
    57721 tcgttcttcg atcgttgtgt catcgggcgt gatcgttttt tccacttttt gagaaaattt
    57781 cttacgttct aagattttct gcatggcacg gatcaaatcg atttttttga cttgtcctcg
    57841 cttcaacggc ttttcagcat ccgctaaccc atcgatgttc ataggttctt ttgtgtaata
    57901 aagacttcgt tcctctgctt tttctgtcag tctttcagct gcatatttat atttacggta
    57961 ttctaaaagc tgagtgacca attcttctcg aggatcttct tcccataatt cttcatcgtc
    58021 tgtgacgaat tcttggacag gaagcaatgt cttgcttttg attgccatca atgtagcagc
    58081 catcactaag tattctcctg caacagctag ctcgagtgtt ttcattgtat ggatataatt
    58141 catatattgc tccgtgatcg tagcgatcgg tatatcatat atatcgattt ccatttgctg
    58201 aatcagatga agcagcagat cgagaggacc ctcgaataca tctaatttaa tattgatctc
    58261 cgtcaactca ttcactcttt cttctttttc tttgctagcc attttccaat gtaaggctct
    58321 gtgatttcag ttgcacggat ggagacatcc gggtactttt cctgtaattc atctaacatt
    58381 tgaaagccca tattctcacc gcgataagac ggattcaaag aaatgtcatg gatgatcagc
    58441 tgatcgttcg ttgcccagta aataccaata atcccttgaa tgttggttga accttctggc
    58501 gtaaagaaaa aaagttcata atcgtcttca gattcgtacg tatcaatctc cttcaacaaa
    58561 gaagttttac ctgtcagttt cttatggaaa ctcaatagtc ccatagcaat tttacggttt
    58621 tctttccggt aatgtgttaa catcttctca ccttcctatg actaagccct tggaaaatgc
    58681 tgcttataaa catccgtcat tcttttcttc gtgatatgtg tataaatctg agtcgtagag
    58741 atatccgcgt gacctaacaa ttcctgtact gtccgcaaat cagctccatt ttctagcaga
    58801 tgtgtggcaa agctatgccg cagcgtatgt ggtgttactt ctttgtaaat cccagcctct
    58861 cgtactaact gcttcagatt tttccagatt ccttgccgag aaagaccttt cccatgatta
    58921 ttgacaaata catgcatttc agatgcgtcc tttacaagta atggacgtgc ttcgtctaag
    58981 tagcgttcca gccattggat cgcataatca cctaaaggaa tgatccgctc tttatctcct
    59041 tttccaactg tctgtaccag tccaagagaa agatgaagat ctcccaattt caatccaatc
    59101 aattcactga cgcgcatccc agtagcatac atgacttcca agattgcacg atctcttatc
    59161 cctaacgttt ttgtcgtatc aggtgcttca atcagctttt ctacttctgt cagagtcaat
    59221 gtacttggta atttctgtgc tttcttcggc gtatcgatat gttgcatcgg atcatgatca
    59281 gtgatacgct cttgccgtaa aaactgatgg aatcttctga gacttgagat catccgagta
    59341 acagttgctg tcgctttttt ttcttcatgc aacttctcca gaaaacggat gactaaaaag
    59401 cgatcgacat cctgccatga agcaattttc tgctcctgta gaaaatgcaa gtactgttcc
    59461 aaatcacgtt catagctttg tcgtgtattg gcggacaatc cccgttcaat attcaagtag
    59521 tggagataat cgttgatttg ctctttcata ataatccccc tcatgcctct ctatcatatc
    59581 agataccgct tcattctgat agtctttttc cataatctga gcaaagaaaa a
//
LOCUS       DAFELK010000012        55371 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFELK010000012
VERSION     DAFELK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.013"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(148..2301)
                     /locus_tag="LP433_000933"
     CDS             complement(148..2301)
                     /locus_tag="LP433_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBL2005113.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2696..3544)
                     /locus_tag="LP433_000934"
     CDS             complement(2696..3544)
                     /locus_tag="LP433_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2005114.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3768..5708)
                     /gene="thrS"
                     /locus_tag="LP433_000935"
     CDS             complement(3768..5708)
                     /gene="thrS"
                     /locus_tag="LP433_000935"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBL2005115.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(6045..6224)
                     /locus_tag="LP433_000936"
     CDS             complement(6045..6224)
                     /locus_tag="LP433_000936"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBL2005116.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6271..8094)
                     /gene="cadA"
                     /locus_tag="LP433_000937"
     CDS             complement(6271..8094)
                     /gene="cadA"
                     /locus_tag="LP433_000937"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL2005117.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8372..10651
                     /locus_tag="LP433_000938"
     CDS             8372..10651
                     /locus_tag="LP433_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2005118.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10744..11391)
                     /locus_tag="LP433_000939"
     CDS             complement(10744..11391)
                     /locus_tag="LP433_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005119.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11570..12289)
                     /locus_tag="LP433_000940"
     CDS             complement(11570..12289)
                     /locus_tag="LP433_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2005120.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12420..13571)
                     /locus_tag="LP433_000941"
     CDS             complement(12420..13571)
                     /locus_tag="LP433_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBL2005121.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13788..14528)
                     /locus_tag="LP433_000942"
     CDS             complement(13788..14528)
                     /locus_tag="LP433_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2005122.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14532..14855)
                     /gene="rsfS"
                     /locus_tag="LP433_000943"
     CDS             complement(14532..14855)
                     /gene="rsfS"
                     /locus_tag="LP433_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBL2005123.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14912..15505)
                     /gene="yqeK"
                     /locus_tag="LP433_000944"
     CDS             complement(14912..15505)
                     /gene="yqeK"
                     /locus_tag="LP433_000944"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBL2005124.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15489..16139)
                     /locus_tag="LP433_000945"
     CDS             complement(15489..16139)
                     /locus_tag="LP433_000945"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBL2005125.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16149..16460)
                     /gene="yhbY"
                     /locus_tag="LP433_000946"
     CDS             complement(16149..16460)
                     /gene="yhbY"
                     /locus_tag="LP433_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBL2005126.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16476..17585)
                     /gene="yqeH"
                     /locus_tag="LP433_000947"
     CDS             complement(16476..17585)
                     /gene="yqeH"
                     /locus_tag="LP433_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBL2005127.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17582..18109)
                     /locus_tag="LP433_000948"
     CDS             complement(17582..18109)
                     /locus_tag="LP433_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBL2005128.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18289..19074)
                     /locus_tag="LP433_000949"
     CDS             complement(18289..19074)
                     /locus_tag="LP433_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBL2005129.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(19067..19936)
                     /locus_tag="LP433_000950"
     CDS             complement(19067..19936)
                     /locus_tag="LP433_000950"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBL2005130.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19937..21316)
                     /locus_tag="LP433_000951"
     CDS             complement(19937..21316)
                     /locus_tag="LP433_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBL2005131.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21324..21743)
                     /gene="fabZ"
                     /locus_tag="LP433_000952"
     CDS             complement(21324..21743)
                     /gene="fabZ"
                     /locus_tag="LP433_000952"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL2005132.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21768..22244)
                     /gene="accB"
                     /locus_tag="LP433_000953"
     CDS             complement(21768..22244)
                     /gene="accB"
                     /locus_tag="LP433_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBL2005133.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22247..23482)
                     /gene="fabF"
                     /locus_tag="LP433_000954"
     CDS             complement(22247..23482)
                     /gene="fabF"
                     /locus_tag="LP433_000954"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBL2005134.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23501..24238)
                     /gene="fabG"
                     /locus_tag="LP433_000955"
     CDS             complement(23501..24238)
                     /gene="fabG"
                     /locus_tag="LP433_000955"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBL2005135.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24250..25167)
                     /gene="fabD"
                     /locus_tag="LP433_000956"
     CDS             complement(24250..25167)
                     /gene="fabD"
                     /locus_tag="LP433_000956"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL2005136.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25274..25498)
                     /locus_tag="LP433_000957"
     CDS             complement(25274..25498)
                     /locus_tag="LP433_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL2005137.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25551..26513)
                     /locus_tag="LP433_000958"
     CDS             complement(25551..26513)
                     /locus_tag="LP433_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBL2005138.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26523..26963)
                     /locus_tag="LP433_000959"
     CDS             complement(26523..26963)
                     /locus_tag="LP433_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2005139.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27269..28234
                     /locus_tag="LP433_000960"
     CDS             27269..28234
                     /locus_tag="LP433_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL2005140.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28291..28521)
                     /locus_tag="LP433_000961"
     CDS             complement(28291..28521)
                     /locus_tag="LP433_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBL2005141.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28607..29494)
                     /locus_tag="LP433_000962"
     CDS             complement(28607..29494)
                     /locus_tag="LP433_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBL2005142.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29583..30806)
                     /locus_tag="LP433_000963"
     CDS             complement(29583..30806)
                     /locus_tag="LP433_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2005143.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30823..31869)
                     /locus_tag="LP433_000964"
     CDS             complement(30823..31869)
                     /locus_tag="LP433_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2005144.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(32033..33760)
                     /gene="ptsP"
                     /locus_tag="LP433_000965"
     CDS             complement(32033..33760)
                     /gene="ptsP"
                     /locus_tag="LP433_000965"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBL2005145.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33760..34026)
                     /locus_tag="LP433_000966"
     CDS             complement(33760..34026)
                     /locus_tag="LP433_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBL2005146.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34505..36739
                     /locus_tag="LP433_000967"
     CDS             34505..36739
                     /locus_tag="LP433_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2005147.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36887..37207
                     /locus_tag="LP433_000968"
     CDS             36887..37207
                     /locus_tag="LP433_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL2005148.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37412..37636)
                     /locus_tag="LP433_000969"
     CDS             complement(37412..37636)
                     /locus_tag="LP433_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBL2005149.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37834..39414)
                     /locus_tag="LP433_000970"
     CDS             complement(37834..39414)
                     /locus_tag="LP433_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBL2005150.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39815..41191)
                     /locus_tag="LP433_000971"
     CDS             complement(39815..41191)
                     /locus_tag="LP433_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL2005151.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41319..42437)
                     /locus_tag="LP433_000972"
     CDS             complement(41319..42437)
                     /locus_tag="LP433_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2005152.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42579..43013
                     /locus_tag="LP433_000973"
     CDS             42579..43013
                     /locus_tag="LP433_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2005153.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(43091..43624)
                     /locus_tag="LP433_000974"
     CDS             complement(43091..43624)
                     /locus_tag="LP433_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBL2005154.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43718..44896)
                     /gene="mutY"
                     /locus_tag="LP433_000975"
     CDS             complement(43718..44896)
                     /gene="mutY"
                     /locus_tag="LP433_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBL2005155.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44889..45686)
                     /gene="recX"
                     /locus_tag="LP433_000976"
     CDS             complement(44889..45686)
                     /gene="recX"
                     /locus_tag="LP433_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBL2005156.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45793..47175
                     /gene="rlmD"
                     /locus_tag="LP433_000977"
     CDS             45793..47175
                     /gene="rlmD"
                     /locus_tag="LP433_000977"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL2005157.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47349..47927)
                     /locus_tag="LP433_000978"
     CDS             complement(47349..47927)
                     /locus_tag="LP433_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBL2005158.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48249..48719
                     /locus_tag="LP433_000979"
     CDS             48249..48719
                     /locus_tag="LP433_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBL2005159.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48827..50053)
                     /locus_tag="LP433_000980"
     CDS             complement(48827..50053)
                     /locus_tag="LP433_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2005160.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(50807..51007)
                     /locus_tag="LP433_000981"
     CDS             complement(50807..51007)
                     /locus_tag="LP433_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2005161.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(51141..51749)
                     /locus_tag="LP433_000982"
     CDS             complement(51141..51749)
                     /locus_tag="LP433_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBL2005162.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(51834..52304)
                     /locus_tag="LP433_000983"
     CDS             complement(51834..52304)
                     /locus_tag="LP433_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBL2005163.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(52352..53266)
                     /locus_tag="LP433_000984"
     CDS             complement(52352..53266)
                     /locus_tag="LP433_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL2005164.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            53412..54215
                     /locus_tag="LP433_000985"
     CDS             53412..54215
                     /locus_tag="LP433_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBL2005165.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            54393..55340
                     /locus_tag="LP433_000986"
     CDS             54393..55340
                     /locus_tag="LP433_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBL2005166.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT        15929 a        11691 c         9447 g        18304 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaac caagaagtat ttaatatttt
     2281 tttcataaaa tctttcatca tttcctatcc ttccgcctat ttacattcat gcttcattgt
     2341 acccaaaaac ttcttaataa acaagaagta tttaatattt ttttcataaa atctttcatc
     2401 atttcctatc cttccgccta tttacattca tgcttcattg tacccaaaaa cttcttaata
     2461 aaaaagaaaa aatgggcgga gcaagaaatt ctttacctaa tttcaagata aaatcaactt
     2521 tttgtttcac agcaatcact taaagttaca tatccaacta tttttttcat taaaaaataa
     2581 acttattttt gaaaattatg ttttcttaag tcgtgaaaca ctttgatgga tcatttattt
     2641 gtggaaaact acgttttgtt attctaaaaa acttatataa aaaatagtaa ggtttttatt
     2701 tcgaatccat aaaatattct tggattgctt ctcgtgtttt tttcactttt tcgctaagct
     2761 tttcgttttt agccatatag aaataaaaaa tgatatcgat cgtagcaaat tgggccaaaa
     2821 gtgaattagt tgccgcactt cgattcgtga tttcttttgg tctagatgtt tgtacgagta
     2881 catcggctat cttgctaagc gggttatttc caaattgcgt caacgcaatg atttcgatat
     2941 tcatgctttt cgccagctcg gctaatgcga ctacatctgc acttctacct gagtttgaaa
     3001 caagccaaag cactttcttt ttctcattgc tgacaagttg cgggagcaag acgtggatat
     3061 ctttttcaaa aatgattggc ttaccgacac gagaccattt ttgcagaata tcttctacta
     3121 ctaaagaaga ggcgccaacc ccatataaaa aaacagtctc tgccgattcc aaacactcta
     3181 cgactttttg gatcgtttct tcttctagaa tatctactgt ttcttttatc gctacttgtg
     3241 cattgttacc aagtttgttt ttgatagagt aaaaggactc atttgcttct atatcactaa
     3301 aaccttcatc gattccagtc tgtagttctg ttgaaatcgt gattttgaag tccgtcagac
     3361 tttgaaaacc gatttttttg gaaaaacgta caactgtcgg cgcactcaac ccggaagctt
     3421 ctgctaattc attagctgtc attgtaggga ccttctcaat attaccgata atgtagttgg
     3481 ccaacttttt ttctgctgaa gaataatctt ccatcatact ttcaatacga ctaattacgc
     3541 tcataagttc ctccaccctt ttaatgatag tctatgtaag tataccatat cagaccctta
     3601 ttcacggtcg tatactggat aaaaaacaaa aaaacaatcc gcccaacaga atatcttatc
     3661 ccatcaatcc cacagattct attgagcatc tgtgtctttg aggaatacct gttatctatt
     3721 gttcggattg ctttctatct actacttttt tacaggaaat ttacctatta gttttctctg
     3781 ctgtaatttt tgacttctgc ttccatagca tcaataaaga tattcaaatc ttctacagct
     3841 gtttctttac ttccataacg acgtacgttc actgttgcat cttccaattc cttgtctcca
     3901 acaactaatt ggtaagggat cttttgtgtt tgagaggcac gtatcttata gcccattttt
     3961 tcattacgat catcaacttc tacacgcaac cccttcattt gcaaacgttc tttgatttca
     4021 taagcataat cgccatgtgc atcaacagaa acagggatga ttgttgcttg tataggtgcc
     4081 aaccatgttg gaaaagcgcc tttgtatact tctgttaaat aagcgacaaa acgttccatt
     4141 gtagaaacaa ttccgcggtg gataactact ggacgatgcg tattttcccc gtcttctcca
     4201 acatatgtca aatcaaagcg ctctggcaat aagaagtcta attgtatagt tgataatgtt
     4261 tcttctgtac caagagctgt tttgacttga acatctagtt ttggtccgta aaaggctgcc
     4321 tcgccttctg cttcaaagta atctagttct aattcatcca tagcggcttt cagcattgct
     4381 tgggcttttt cccacattgc gtcatcatca aaatatttat ctgtattgtt tggatcgcga
     4441 tagctcaagc ggaaacgata atctgtaata ttgaagtcag catatactgc caccatcaat
     4501 tcaagcgtac gtttaaattc atctttgatt tgatcaggac gaacaaatgt atgaccatca
     4561 ttcaacgtca tttctcgtac acgttgtaaa cctgacaaag cacctgattt ttcatagcga
     4621 tgcatcattc ctaattcagc gatacgaatt ggtaattcac gataagaatg gatcgtgttt
     4681 ttgtagacca tcatgtgatg agggcagttc attgggcgaa gaacaagcat ttcgccatct
     4741 cccatatcca ttggcgggaa catgtcttct tgataatgat cccagtgtcc agatgttttg
     4801 tacaactcaa catctcccat tattggtgta tatacatgtt ggtaacctag actaacttct
     4861 ttgtctacga tataacgttc gatcgtgcgt cggattgttg ccccttttgg aagccagaat
     4921 ggcaaaccag aacctacttc tggggaaacc atgaacaagt caagttcttt tcctagttta
     4981 cgatggtctc tttcttttgc ttcttcacgg agacggatat attctttcaa agctttcttg
     5041 tcaaaaaagg ctgtcccgta tacacgttgc atcatttgat tgtttgagtt tccacgccaa
     5101 taagcacctg ccactgataa taatttaaat acttgtatac ggccagtgga tggaacatgt
     5161 ggtccacgac acaaatcgat gaattcgcct tgttgataag cagtaatcac ttcttcttct
     5221 ggcaattcac taatcagttc tactttgtac ggatcacttg caaaaatttc taatgcttcc
     5281 tgttttgaaa gaacacggcg ttcgatcggc agattttctt tgacgatttt catcatttct
     5341 gcttcgattg ccggcaaatc ttctgcagtt acttggtttt gtccattatc tgtatcgtag
     5401 taaaaccctg aatcgatagc tggtccaacg ccaaagtgga tatttggata gaggcgacgc
     5461 atggcttggg ccatcaaatg agctgctgaa tgacggacta agccaagtgc atcttcatgg
     5521 tctggtgtga tgatctcaat acttgcatct tcctcgattg gacgagtcaa atcaacgagt
     5581 tttccgttca ctttaccagc taaagctttt tttgctaagc tttttgaaat gctttcagca
     5641 attgccaatg ttgttgttcc agactcaaat tctttgactg caccatctgg aaaagtaatt
     5701 tttatcataa tagtttcctc cttgaaatgt tttgattgat cagatcatca agctgaaaaa
     5761 caaaaaaatc ctagcatctc ttgaaaagag atactaggac gaaaagttcg tggttccacc
     5821 taatgttcaa acgcaaatgc gttcctcaag cgttgtaacg gtccgaccgc ccttgcttca
     5881 acaagggttt cgaaagtggt catcctttgg ttttctcctg gaaaagtttc agcctagctt
     5941 ttcctctctt atcgaagact ctcaaattca gttggctttc tcatcaatca attatgtgtt
     6001 tatttaacca ctaataaata gaaaaatcaa gtgggaaact aaacttattt tttccattcc
     6061 ccatttacac cgtatgttcc ttttttcatc tcattgatga tgacatggat gtgttctttt
     6121 ggtgcctgcg tgtttttatg aacagcttcc gtgatatctt tcatcatatt ttctaattgt
     6181 tccggactgc gaccttctac taattcgaca tgtacgaatg gcataatgct ctctcctctt
     6241 tctgatcgtt cttttttcaa ctcgattcta tcatactatg tttgtcttgg gtactgaatc
     6301 aggaaaaatg gctggatctt tttttgctct caaggcactc aaaatagaga ccgtatccac
     6361 gacttcttgc aaaacagctc cgaataatgc ggggattagt cccgtacttg caattaacat
     6421 caaaaaaata caaataaaga tgccaatcag tacagactgt ttcgctattc tcatcgtatc
     6481 tcttgaaatc actactgctt ttgctacacg caagagatca tctttcaaga tgaccgcatc
     6541 tgcactttca ctagcagctg tagaaccatg agcccccatt gcaataccga tatctgcagc
     6601 agcaagtgct ggtgcgtcat tcacgccgtc tcctaccatc gcaacaggtc tttgatcttt
     6661 agggatactt tctaaaatgg tcagtttatc ttgaggcaag ctacgggcat gtacagaatc
     6721 taattggact ttttctgcaa tcgtttgagc aatggcagat ccatccccgg tgatcatcat
     6781 caaatttttc acatcaagtt ttcttagctc cttgattgtc tttgctgctt ctgggcgaat
     6841 ctgatccgaa aataggatcg ttcctgcaaa agatcgatca attgttacat agattgctgt
     6901 attggacgtt tctatttctt cagctgaaac aaaagaggca cgtccaatct ttacttcatg
     6961 attattgact actgcttgga ttccttgacc ggtcacttct ttcagttgac taacaggata
     7021 cagttggctg tttttcacgt tgttcactaa cgaacgagct aagatatggc tagattcctg
     7081 ttctgcacta gctgcataca gaagtagctc ttcttttttt attccattga ctggctgaat
     7141 cgcctctact tccaatatcc ctttggtaag cgttcctgtt ttatcaaaag caatcgtttt
     7201 tgtacgtgcg agcttttcaa tcgttgttcc agtttttaca acgatcccgt ttttacttga
     7261 acggctcatt cctgcaacta aagcaatggg cgcagctaga atcagtggac aaggtgatgc
     7321 cactaccagt acctcagcaa atcgtaaagg gtcttttgag aaccaccaag aaataccacc
     7381 gatcaaataa gcaatcaacg tgaaagggac tgcataacga tcagctaaac ggacaaatcg
     7441 ggcaggcttt tcttttgatt cttcgactag tttaataatc atttgatact ggctgtctgc
     7501 ggcacgtttt tcagcgatca tttggatcga tccgtctcca tttaaagacc ctgacataat
     7561 ctgatctcca ggtttcttgg tttccgggcg ggactcacct gtcaaagaag attcatcgac
     7621 cgaagattct cctttggtca ctcgaccatc tgcgggtaca agttcgccag gcttgactag
     7681 taactggtca tcaatattta tttcatcgat tactatatcc tgcaattttc cttctttgaa
     7741 tcgatgggca attcttgggg tgttatctaa caaagactgc agttctttac ccgctcgttt
     7801 attcgcgtaa tcctctagac tatctccgcc cgtaagcatg atcaatatca tcaaactagc
     7861 ccagtattct ttgacggcta atgttgcaag gattgcggta atcgctaata catctacgcc
     7921 atatcttcct gaacgtaacg tcttgatcat ttccaaaaac atcaagaagg cgagaatccc
     7981 tccagtaaat gcgacaatcg caaatgcaag ggccggctgg tgaaaaacaa attcacttaa
     8041 taaagctatc ccaccaataa gcaaagtaag taaaaatttt ttgaaatgtg tcattgtttt
     8101 ttctcctctt ttatgtgact tagagaggtt agtaataaat ttccagctgc ctctttcatc
     8161 ttaagcatag tccttgacta gcacttttta aaacaatagg ccttaattga aaacaactat
     8221 cactatcagc gtttccaaaa ttcatcagtt ctacaaacaa aaatattcag caaggattac
     8281 tttttcgatt catcagttaa aaagtacctt ttttcgaaaa actatgctat acttttaatt
     8341 cgttatttac ggcggaagga gcaaacatgc gatgaatgag aaacaactag aacaaacgca
     8401 cgtggatgaa acgatcgaac taatccagat cgaacaaaat atgctggata caaaacaaca
     8461 agaattgact caggaaatga atcattcgac aaaagacaca gctaatcaca agattcgagc
     8521 tggttccaat gaagcttttt atgaatctgc tgttgaatat cgccaacatg agcaggaatt
     8581 gcttttgaaa taccatactc ttgaagcaca gcaaaaacgc ctgcaaacgt tgtctgtcat
     8641 gaaagatagt ccttattttg cccgtatcga ctttaaagaa gaccgtgaaa cagaaacatt
     8701 atatctaggt atcgcttctt taagagatct ggcagaagaa acaatcgtta ttgactggcg
     8761 cgcaccaatt gccaatcttt attatgaagg tgagattggt cccgcatttt atgaaactga
     8821 aacagataga atagatgtcg atctgcagtt gaaacgacaa tttaaaatcc aagaaggacg
     8881 tattttatct atggtagata cgtcggaagt aatcaatgat gactttttgc tagagatatt
     8941 ggatgaatca tcaagcaacc atatgaaaaa catcgtctct acgatacaaa aagcacaaaa
     9001 tgcaatcatt cgggacacaa caagtaaagt aatgctgatt gaaggaatcg ccggaagtgg
     9061 aaagacatcc gctttgcttc aacgtattgc ttttctgttg tatcataatc gcaagtggct
     9121 cgaggctgaa aacgttcttc tattttcacc caaccatttg ttttctgatt acatctcgac
     9181 tgtattgcct tcattaggtg aaagcggcgt gcctacacag acattcaaaa attatttggt
     9241 gcagctgctg ccagagtttt ctttactaga tgaacagcaa caagaaagtg gttttttgct
     9301 aggggaaaaa gatccgatac aagtgatgaa aagcggattg accttagtcg atcagattga
     9361 tcgctatatc caaggcatca caaactacgg tcccttgttc cgtgatatga aaataaatgg
     9421 ccgtacgatc ctatcaaagg aatcgattcg ccaatggtat aaagaaacaa atgaacaatt
     9481 acctttacat catagacttt ctctattaca aacgaagctc ctgaaaaaat taggcggtct
     9541 gcaaaaagac gaaacacgtc agcaatgggt caaagatctg gcggaagaac agctccaaga
     9601 actatacgca acagatccaa atcttgaata tacagaacaa aaggagcgtt cattacgtaa
     9661 aaaactggcc aaccaaatcg tacgtaaaag attccgtcga atccatcgag ggatcatgaa
     9721 ttatcaattt gtcaatataa cgaaacaata tctccacttt ctacaaactg tgccactttc
     9781 tcttctaaca cgacataaaa tcagcgagac caggtggcag gaacatttga caactgttcg
     9841 tacacacttg cgtcaaagag aattgcgtca agaggatgct gtactattct ttttactgat
     9901 gcgccgaaca tatccagtga cggttacaca caaagctcgc tatatcttta ttgatgaaat
     9961 gcaggatttc gcaccatcac aagtggcatt gctgcaagcc ttgttcccaa aagcaaattt
    10021 gactttctgt ggagatctaa atcaaaatgt ctttggaaat gaaacgatcg ttggatcatt
    10081 ggaagacctt ttcgtggacc gtgaagtcac tcgtttccaa ttaacgacaa gctatcgctc
    10141 cacaaaagaa atcactgatt ttgctaatca ttttattgtg aaagaacatc aagtagaaac
    10201 aacagcaaga aaaggagacc ttcctttgct catccaagga acaacagatg atatcaaatt
    10261 gaattggtta gcagatacca ttcgaacgac tcagggaaaa gcccggtatt ggcgtacagc
    10321 aatcatagct aaaacacaag aagaatgcga agctctttat gctcaactgc cagacgagtt
    10381 gaaacaacaa gtccagctga ttttaaatga gagtgacttt atgaagcgtt ccattatttt
    10441 acttccagcc tttttagcaa aaggtctgga gtttgaccga gttttcttgt gggatgtaga
    10501 tgcagaacat ttttcttctc agcaagacaa attgatcctt tacaccatgt gtacacgtgc
    10561 gatgcatgaa ttgacccttt ttacctccaa taatgaaagt cctttgttaa acaatatgga
    10621 tatttcatct tatgagaaaa aagtactgta agtaaaaaga caactgctat cattaatgtt
    10681 agcagttgtc tttttattta caataataat tgcagaaaaa gtaattcaat catttaaggt
    10741 catttattct atatataaat ccaaatctgt ttcaggatat tttaatttga caagcgaaat
    10801 aatcattttc agttcttcca tgttttctgg atattctggg tcaaatacct tgctatgacg
    10861 gccaatcccg ccattgtcga tcaatcggta aattcgattc cattcaatga attggtcaat
    10921 tgattggaaa ttgctgattg gatagccgcc acaatccaaa atctctgata cacgaaatgc
    10981 taggtatgca ctatcgatca ctttattttt tttcgtgtct atcttctcat ttctttcgat
    11041 aagaattttt tcaggacgat gtttcaagct ccactctaat agtagaaaga aagcctccat
    11101 ccgatactct tcttcaaata accgaaaggc tgaatcagaa cgacgaaaaa gcagcggaat
    11161 cagataattt tgtctataaa tcagcattgg tgcgcggtcc accatacact ctaaataacg
    11221 gttcagatac cctgtaccga catagtttcc taatcgatag ccttcaacgc cgaatcttgc
    11281 gtatttttgc gctaattttg aacaatcagt tacgttcaca gctaactctt ctactttgcg
    11341 gtaaccgctt aagatacgtt caaaaggttc taaagtgatt tttgcttcca tattcttccc
    11401 cgtccatctt ccacatactt catatcattt cacatgatac ttatgctctc atcataccac
    11461 aggttgaatt agaaaagaaa ataaatcaca caaaaaagca agacaatctg ttagtgagat
    11521 tgtcttgctt ttcgaaaaag actgaatact tttcgttaaa actggttgct tagtcttcta
    11581 atgccacatt atggaacaca tgctgtacat cttctagatc ttccagtgca tcaatcattt
    11641 tttcaaatgt ttcttgatct tctggagata gtgttacctc gttttgaggg atcatttgga
    11701 tctcagcgat tgaaaaatca gtgattcctt tttcttttaa tgcttcttgt atactatgga
    11761 aatccgctac ttcaccgtaa acgatgattt gtccttcttc ttccattaca tcgcgaacat
    11821 cgatgtcttt ttccattagg tattcaagga tctcgtcagc gtcttctcct gcaaaagcaa
    11881 agattgctgt attgtcaaac atgtaagaaa ccgctccgga aacacccatg ttcccgccat
    11941 ttttcccaaa tgctgcccgt acgtctgctg ctgttcgatt cacattgttc gtcaatgtat
    12001 caacaatcac cattgagccg cttggtccaa atccttcata gcgcaattca gagtatgttt
    12061 catctcctgc accttttgct ttttcgattg ctcggtcaat aatatgtttt ggtacattat
    12121 aagttttagc gcgatcaatg acgaaacgta gtttttggtt tgcatgcgga tcaggatcac
    12181 ctgattttgc tgccgcgtag atttcaatcc caaattttgc ataaatccgg ctattattag
    12241 catctttagc agttttcttt gctacgatat ttgcccattt acgtcccata ttttcacttc
    12301 gctttctgat ttgatagttt cataacgcaa aaacgtcctg ttccattata cttgtgaatc
    12361 acgattctgt gaagcttttt ttctttcttc cttcattctt ctcattttta gtcaattatc
    12421 tatactcgga ttgggatttg cccgaaattc tgttccggaa tattgcctcc caattgatag
    12481 atttgatcac ttctaactaa cagttccgct tcttgtgcct ctttttttcc gattcgggaa
    12541 taaatagaaa tctctttttt ttcttttaag aatcttcttc cagcatcggt aaatccaagt
    12601 agtcgaagat aatttttatt ttgttggaca ggaatctctt gctttttgat attcagcaag
    12661 acataacaag ataatcgttg gatccgtgtc catgtatatc tttttgtttt tacctttgac
    12721 acaaaatcct caaaactatc agcagttgca gctgctgttt tcatgcgcga ttctattcct
    12781 tcggtcatct gatagatatc tgtcagttcc agcaaagtag aagataacaa ccgataacgc
    12841 aaatacggcc aataagattc ccaagtctgc agcgaacaag ttgaaagatc ttcttctgtc
    12901 tgaggcggca caagtccagc tattcttttt ccttcttcta acgcatggcg aatggctgtt
    12961 gcactggcta tcctctgatc tgtgatgatt ttttcatgat agcctgcact tttacgtcgg
    13021 atcggatgta attccatagg gtggacatac ttggcatttt cctttgcata acttaatccc
    13081 aagatatgat ttggcgaaga aaaatcaagc gtaatatcgg gatacagact gcgaaaaacc
    13141 tcagtcattt tttgcggata actatacgtt tgatcagaca gttcttgaaa tgcctcttct
    13201 atcctatctt gattctcttg gacaaagcgt ccgaaactgc tgtaatcaaa cgaagtctct
    13261 tcttctgttc caaaacacaa actgtcacag tccagtgttt gcaagatttt tactgcacct
    13321 ttagcaaaat agtcagctga ctgaaccgcc cattcgacgg gaagctccac tactaaatcc
    13381 acaccatttt gtaaagcttc attcgcgcga tgccatttat cgatgatagc cggttcgcct
    13441 ctttgcaaaa aattcccgct cattacagca atgacgacct ctgctcctgt tatttttcgt
    13501 gccatttcca catgatagcg atgtccattg tgaaaaggat tgtactctac gataatcccg
    13561 cagcttttca tgcgcatcct ccttcatagt tatcgataaa aaagaaatag agacaagtaa
    13621 aaaaaggcaa aaatcggaaa aaatacccga actatataaa ctattctcgc aaacacaata
    13681 cttctgcgac gaaaagctgc actgcaagag caatgcctat atcgttcgga tatataattt
    13741 atgttgaaga tttattcttt tcttgttaac tcgagcaggc aaaaccgcta gtctttgtat
    13801 gctacaaaga accagcgctt tgatttctct gatgctgctt cgtctgtaaa atcagaaaat
    13861 gcttcgactt tcgaaaagcc gctgttttcc agcattctta aataactttc caatggatag
    13921 gtacgctctt gatgtagttc atcttcacga ataaatcgac cagacccttc ttgttcttca
    13981 acgaaaaagg taagaaaatg ttcgatgctg tgtttctcgc ttcctggata actatcccac
    14041 aaaaaagcaa aattatcccc ttgataatga tagctatatt ctggaaaaac ctcatctact
    14101 tgataggtgg agtgtacgtc aaataaaaat cggccatttt cttctaacgc ttgatagact
    14161 tcatcaaaca cttgctgtac ctcttgtcta tttttcatat agcacagcga atcagaaaaa
    14221 caggtaattg cctgatattg tccgatttct gataaatcga gcatattgcc ttccacaaat
    14281 tggatcgatg cgtcttcttc atatgctcgc tggctggcaa tcatcaacat ctcttctgaa
    14341 aggtctaacc ctgtcacttt atatccatct tttgcaaagg caaccgctaa tgctccagta
    14401 ccgcatgcca gttccaaaat attttttgtg tcttcttgta aatgacgttt cgaaaaagct
    14461 aaccattgct gataaagtgt ttcgtccatc acttcatcgt aaatgaaagc aaatgtttca
    14521 taagccatat gttaatccaa ccattcacta agatcgacta gcggagcatc tgaccatagt
    14581 ttttccagat tatagaaatt tcgttctggc gcatggaaaa catgtacgat cacatctcca
    14641 agatcgatca atacccattt tccgccttct tttccttcaa tacgttttac ttcatatttg
    14701 ttttcttctt ctttatcaat gatttcttct gtaattgcgt tgatttgacg ttcgctattt
    14761 gctgaacaga tcatgaaata atctgccaac aaggaaacat ttcgaacgtc taaagcgata
    14821 atgtcttctg cccgttttga atctgctgct tcaatcgcaa tttttaattg ttctttacta
    14881 tctatgatga tttcctccta atatgagcag cttatttttt tgctacccag taattatatg
    14941 tttcgattgt ttttggataa atctgttgtt cttgcgcaag caaatgggcc aatgtatgtt
    15001 ttgtttcaaa tgctacagct tcgtctagat cagcccatgc aatggctcgt gcatcttgta
    15061 ccccaggaaa atctcgacct ggttcaatat agtctgctac ataaatgatt ttgtcaagga
    15121 gactcatctt agcagcccca gtcgtatgca cccggattgc atgaagaatc tctgcatcgg
    15181 tgattcctaa ttcccgctct acaaacgaag cgccaacaag accatgccag attgcattat
    15241 tataattcaa taactccgga tcaaaaccgt ctcttacgat taccattttg aactcctcat
    15301 ctggtcgttc ttttgcataa tcatgtgtca atgcagcaat actagctttt tcaggagaag
    15361 caccgtattt tttggcaaga gccacggctg tttcttctac tccaagcaca tgcttgaagc
    15421 gttgttcgct cattctcatc tgtatttttt gcatcaggtt ttctctagaa taagcagtat
    15481 attcattact atagtccata ttcatacaac ccttcatttt gaatataatc aattacttta
    15541 tctggaacaa ggtagcggat agaacagcct tctttgatct tttgacgtat tttcgtggaa
    15601 ctgatgtcga tctcaggtac atctacccaa attacaggat atggagtatc cgttgtgtat
    15661 cctggtcgac gtatacccac aaagttgacc atagaagtca gctcatcgat tttataccat
    15721 tttggcaaat attctaccat atccccaccg ataataaagt aataatctgt atccggattg
    15781 ttttgcgtca attccttcat agtatcatag gtgtaacttt tcccaccacg agctaattca
    15841 atcgtttcaa tctgcaaaaa aggattgtct tccaccgcta attccaacat gttgagtcga
    15901 tgttttgcat caatcgtctg tttctcatca acatgaggtg gctgataaga aggcatcaaa
    15961 aatacgcggt caagacctaa attccggcca gcttgttcag ccatcactaa atgtgcaagg
    16021 tgaacgggat tgaatgttcc gcccaagatc cctacttgct ttttcttctc taagaattga
    16081 ggcatttctt caggaaataa ttgtgaacga acaaatgtct tagcttgcgt attcatcatg
    16141 gtcactcctt atattgcttt tacttctttt gatagccttt gatacttttc ttttgtggaa
    16201 ggtttgtata atacaataac acgtccaatg atttggacga tttcgcaatc tatttctttt
    16261 tctaatactt gagctgcttc ttctgcaatc tcatctgtat tttgaagtaa cgatactttg
    16321 atcagttctc ttttttctaa agcttcttca atttgaacga tcattgctga attgatccca
    16381 ccttttccga tttgaaaaat cggctgaaga tgatgcgctt tgctacgtaa aaaacgcttt
    16441 tgttttcctc ttaaactcat aattttcctt cttccttaaa tcaatgcttt gcgtttcaat
    16501 acatctacac cctttggcgc ccagcccgca attactactg gcgctgttac agtgatccag
    16561 cctagaccgg caaaaacgat gtctgttttt tctttcacag aaaactcaaa acgaacaagc
    16621 tccggaaatg cctcgacttc atcaggacga ggaggctgta ataatccacc tacatgtttt
    16681 tgataaaatt cgtctgcttt ttccagtttc gttcgatgaa tatttacatc atttgacaca
    16741 taagcaataa atgaagcacg attgccgctg ataaaatcaa atcttgcaag tccgcccaag
    16801 aaaagtgttt gcccttcatt cagctgataa actttaggtt tgatttcttt taacggtgca
    16861 atgatccgca aatctttttt acctaagtag tgcgccattt gatggcgatg gataattccc
    16921 ggtgtatcaa tcaaaaaatg cccgtcatct aaaggaatct cgattttatc caaggtcgtt
    16981 cctggaaact gcgaagttgt gattacatct tgtactcccg ctgtattttt gatgatttga
    17041 ttgataagcg tcgattttcc gacatttgtt actccgacga tatagacatc ccgtccatcg
    17101 cggtattctt cgattttttc taatagttcc gtcatctcat gagatttctt agcactagtt
    17161 aataatacat ctactggacg aattcctgct tcgtaagcac gttccttcat ccattgtgtt
    17221 aatttagttt ttttcaatga tttaggtaat atatccactt tgttcccaac taaaagtact
    17281 ggattgtcac cgacaaaacg gtgtagtcct gggattagtg aaccattgaa gtcaaaaata
    17341 tccaccacat tgacgatcaa tgcatctttt tgccctaatt cattcagtaa gcgcaaaaag
    17401 tcgtcatccg tcaatgagac atcttggatc tcattataat ggcgtaatct gaaacaacgc
    17461 tgacaataga cttccccgga agctaaacct ttttccaaag ccgtttgcgg cgtgtatcct
    17521 aattcaccgg gtttgtttgt ttgtataacg gcaccacagc cgatacattg taattcttct
    17581 gtcattcgat tccacctcgc cagcccatat cagggtgttt tgctaataga taggccataa
    17641 ttcttttttc ccaaaaacga ttaaattgtg tcttccaact atctgttgcg ataatgggtt
    17701 ttacaaggat gctacgtatc cctgcacgat tggctccacg tatatcagtc ataatctgat
    17761 cgcctaccat tactatctca tcatctgcta aatccaattg tttctttgct atgttgatcc
    17821 ctcttgctaa aggtttcatt gctcgtgcaa catacaaaag atcaaatttt tcaatcgctc
    17881 gcgcgacacg ttttgaatta ttgtttgaaa caacaacaac agggattcct gcatttttca
    17941 tttctaaaat ccaagtaagc aactcttctg ttccatctgg attattccat gcaatcaacg
    18001 tattgtctaa atcggtcaat actgctttga tgcctagatt ctttaattgg gcaggtgtaa
    18061 tctgatagat ggcttctacc atccatgttg gtttgtaatt tgaaaacatg ctgtctcctc
    18121 atctgcaaaa aatgaaggag cacataaagt actcctcaac cccgtattat actgcatatc
    18181 agcaaaaaaa actacctcta tactcgttcg tctttcagaa aaagcatttc tttacaaaat
    18241 gaccaaaaat aaagattgat cacagaaaaa tttagaaaca aaaaacaact aatattggcg
    18301 gaacctcttg tatcgttttt ccagtaattt atgctgatct aatcgaacaa gttccgtcaa
    18361 tctttcaatc aacgcttttt tcataatgtg tgcgacttta tatcgtggca actgctcgcc
    18421 gttgaacgtt tcaggaataa ctcgatcaac gattcctaac tcgcgtagtt ctggcgcagt
    18481 aattttcatc aactcagctg cttctgcggc gcgactaccg tctttccaca aaatcgacgc
    18541 aaatccttct ggagaaagca cagcataaat cgtttcttcc agcatccaga cttcatccgc
    18601 taaacctaga gcaagggcac cgccacttcc accttcacca atgatgatgg cgatgatcgg
    18661 tacctttaaa tcagacattt cgagcagatt tctggcaata gcctctcctt cgccgcgctc
    18721 ttctgctcct acaccgcaat atgcacctgc tgtattgatc aaggtaatca ccggtctatt
    18781 gaacttttcc gcttgtttca tcagtcgtaa agcttttcga tagccttcag gatggggaga
    18841 accaaaattt ctgcggatat tttcctgcag atcccgtcct ttttgaatac cgatcactgt
    18901 taccggtttg ccatctaatc gagcgattcc accaacaatc gcttcgtcat ctgcaaataa
    18961 acgatcacca tggcattcct cgaaagaatc gaagatctct tcaaaaaaat ccaagcttgt
    19021 ccatcgttct ttagctcttg ctaactgaac gacatcatgt gctgtcttat ccacgatcta
    19081 tccatccttt ctgtgtatgc aattcaagaa gcgtatggat tttctgtttc aattccatgc
    19141 ggggaacaat ctgatcgaca aaaccatgag ataataagaa ttcagccttt tggaaatctt
    19201 ctggaagttc ctgcttgatc gtctgttcga tgacgcgtct tccagcaaaa ccgatcaagc
    19261 tttggggttc tgctagaata atatcgcctt ccattgcaaa actggcagtt actcctccgg
    19321 tcgtcgggtc cgttaaaaca gttagataaa aaagaccttc attgctatgc cgtttgacag
    19381 cagcagagat ttttgccatc tgcattagag aaaagattcc ttcttgcatc cgtgcgccac
    19441 ctgaagctgt gaacaagacg actggaagac tttcctttgt tgctcgttcg aataatctgg
    19501 tgatcttttc tccgacaatc gttcccatac ttcccatgat aaaattagga tccatcactc
    19561 caataatgaa gggaatcccc tgaatggttg ctttaccagt gaggactgct tcatgaagtc
    19621 ctgttttatc ttgcattttt ttaatttttt ccgtatattc gggaaatgct agcggatctt
    19681 tggttacaag atccgtatcc cattcttcaa aacttttttc atcaataatc aaagctagac
    19741 gctgccatgc accgattcga aaagcgtatc cgcaatgagg gcatactttt tcttcaccga
    19801 tgtctttcgt ataaaggata tgtttgcaat ttggacactt tgcccacatg ttatcaggaa
    19861 cagatggcga gttagcaggt ttgctctctc tattaggatt gatccgaata tatttctttt
    19921 tcttaaacag agccatctat gcgcctccta tctccgtttc tggtgtccaa ttcggtaaaa
    19981 attcttcttg taaaaatgct gtgctgtaat cacctgctat gactgcagga tgactaatca
    20041 aatccatctg aaattctgcg ttcgtgatga ttccttctgt gataaattca cttaaggctc
    20101 gctgcatctt cattaatgct tcaaaacgcg tatttccatg gacgattatt tttgcaatca
    20161 ttgaatcata atatggcggg atcgtatatc ccgggtaaac tgcactgtct actcgcagtc
    20221 ccatcccacc tgctggaagc agtaagtttt ggatcttccc tggagaagga gcaaaatgga
    20281 aagcaggatt ttctgcatta atccggcatt cgattgcgtg tccttggaat actacttctt
    20341 cttgacacac attcaaaggc tcaccggctg ctatctccac ctgttttttt actaaatcga
    20401 ttcctgtgac catttctgtt actggatgtt ccacttggat tcgagtattc atttccatga
    20461 aataaaaatc gccttcttca tccatcagaa actcgatcgt tccggcattt tcataattga
    20521 ctgctttagc tgctcgaaca gcagcgtctc ctagtgcttc tctttttgtt tgtgagatca
    20581 ctacagaagg agattcttcc agtacttttt gattgttgcg ttgtaaagaa caatctcgct
    20641 cgcctaaatg aatgacatga ccaaatcgat cacctaagat ctgaacttct atatggcgag
    20701 caggataaat gattttttcc aaatacatat catcatttcc aaatgccgct gctgcttctt
    20761 gctgagctga agaaaaatgc tgtgggagct cttcttttga ttgaactttc cgaatgcctt
    20821 tcccgccacc acctgcagct gctttcagca tcactggata accaattctg tctgctattt
    20881 ccaatgcttc ttctactgta gataatacac cagtacttcc tggaatgact gggacatttg
    20941 cttcttgcat caattgacgc gcattgatct tatttcccat tgcatcgatc gttgcacttt
    21001 taggaccaat aaatgtgata ttgcactctt cacacatgga ggcaaatcgg ctattttcag
    21061 ataaaaaacc aaatcctgga tgaattgctt cggcttttgt cacgattgca gcgctcagta
    21121 cttcctgaac attcagatat gaatcaacgg cttttgccgg gccaatgcag attgcttcat
    21181 ctgctaactg tgtatgaagt gcttcggcat ctgcttctga atatatcgct acggtttgga
    21241 tccctagttc gcggcatgca cgaatgatac gtacagcgat ttcaccgcgg ttagctatca
    21301 atactttaga aaacatattt cacctatcca atcataaagg ttaattccgc ttcggctact
    21361 tttttaccgt ctactttagc gattcctttg cctattccgg ctgaagcttt cactttcaat
    21421 atctcaactt caaggtataa ggtatctccc ggtgtaactt tcttacggaa ttttgctttg
    21481 tccaatccgc cgaaataagc cgtctttccc ttgaattgtt caagagaaag taatgcaact
    21541 gctcctgctt gagccattgc ttcaacaatc aatacccctg gcataacagg ttcttctgga
    21601 aaatgtcctt gaaaaaaggg ctcattgatc gttacatttt tcttagcaac gatccgttct
    21661 ccttcaacca tttcttccac tcgatcaatc aaaagcattg gataacgatg tggaatgatt
    21721 tcttttattt cttgtatgtt cattgttttc cctctttcct gctttgctta tttttgctga
    21781 atcctaaaga gtggctgtcc atattcgaca actgactcgt tttctacaag gatttctgtg
    21841 atcactccgt cggcctcact agttatctca ttcatcagtt tcatcgcttc aataatgcag
    21901 ataacttctc ctttggcaac ttgatcacct acttttttga aagctggttt gtcgggcgct
    21961 ggttgcagat aaacgattcc cacgattggc gaaacaacct cgattccatc aaatactgcc
    22021 gattcttttt ctttcattat ttctggagca gttgttgctt gttcagatat gacattgact
    22081 ggctccgaaa ctggcaacgt ttcgtttgtt tgaaccatat tcatgcctcg acttgtttta
    22141 tttttattca tatacaattc aaattgacct tcacgcaaat cgaattccgt tagcgaggat
    22201 tgatcaaatt gactgactaa ttctctgatt tcattgatat ccaaaattat tcctcccagc
    22261 gtttcatgca cagaaccgca ttatgtccgc caaaccctaa tgaattactc attgcataag
    22321 taaaacttgc aggtttgctt tcgtttttga caactgtcaa gtcaatctca ggatcttgtt
    22381 tttctacatt gatcgtaggt gggataaatt gatgttctaa tgccagcaaa gttgccaagg
    22441 cttcgatccc gccggctgct cccaataaat gtccagtcat cgatttcgtg ctgctgacgt
    22501 aagtatctct gaaattttca cctaatgcga tttggattgc ttttgcttct gcctggtcat
    22561 tggctggtgt acttgttccg tgagcattga tatatccgac ttgttccggc tgtacaccag
    22621 cttcttccat cgcaagcttc attgctttag atgcaccaga accatctgga gtaggagctg
    22681 tcatatggta agcgtcacag tttgcaccgt atccaacgat ttctccatag attttggcac
    22741 cgcgagcttg tgcatgttct aaagattcaa gaactagaac gcctgctcct tcacccatca
    22801 caaaaccatt ccgattttcg tcaaacggaa tcgaaccacg attaggatca gttgattctg
    22861 agagtgctgt taaagctgca aatccagcaa tccccatctc acaaatcgtt gcttctgttc
    22921 ctccagcaag aatgacatca gaatagccat gtttgatgtt acggaatgct tccccaattg
    22981 aattcgttcc gctagcacaa gctgttacga tagctgtaca aatacctttt gcacctacac
    23041 gcaaagcaat atttccagct gccatgttgg caatcgccat tggtacgaac attggagaaa
    23101 ctcgttttgc acctttttca tgtagacgaa taacttggtt ttcgattgtt ggaagaccac
    23161 cgatcccaga tccgatgatg acgccaaacc ggtcttgatt cattttttct ttatctaaac
    23221 cgctcatctc cattgcttct aaagcagcgt agattccata gatcgaaaac atatccattc
    23281 gtttgctatc ttttttaata aaatatttat cgtaagggaa atctttgact tcacccgcta
    23341 aggtaatccc tgtttctgaa gcatcaaatt tagtgatcgg tgcgatgcca ttcgtcccct
    23401 cttttaagct attcaaaaag ctgtctgcgt catttccaat aggtgaagtg actccatagc
    23461 cagtaattac cactcgattc atttgtttgc tctccttttc ttatccgtgc atgaccaatc
    23521 cgccatcgac attgatgact tgtccggtga tatatggatt ttgtgctaag aaaactgctg
    23581 tttgtgcaat atcttctact tgtccgaaac gctgcatcgg aatttgcttt tccgcttgtt
    23641 ccttgacttt gtctgctaaa acttccgtca tatcagttgt gatgaatcct ggcgcaatgg
    23701 cattacatgt aatgcctcta gttgcagctt ctcgtgccac agattttgtt aatcctacta
    23761 cgccagcttt actagctgca taatttgctt gaccaatatt tccaatcaac ccagatacac
    23821 tagagagatt aatgatggcc ccttctcgct gcttcatcat ttttttcaat acgtgctgcg
    23881 tcatattgaa ggttccaatc aaattgatat ccagacattt tttgaaatct tctgcatcca
    23941 ttcgcatcac aagtttgtca tttgtgattc cggcattgtt tactaacaca tggatcgatc
    24001 caagcttttc ttctgcttct ttgatcattt gtcccgcttt ctcataatca gagatgtcac
    24061 cggaaactcc tacgcatttt acaccgaatg cttcgatttc ttctatcttt tcttttggaa
    24121 tctctccgcg accattcaaa atgatatttg ctccagcttt tgcaaaagct aaggccatcg
    24181 ctttgccgat tcctcttgta ctacctgtga taaatacatt ttttcctttt acatccataa
    24241 cgttcctcct tatagtattg ctattgtttc atcaaatgtc tgcttattct caacacgcag
    24301 aactggtatt gttttatcga tttttttcat aaatccgctt aatacttttc cggggccgac
    24361 ttcgatgact tgttcgatgc cgattgtttt taacttatgg atactctcat agaaacgaac
    24421 aggttgcatg acttgctgtt caagtagtcc cgcgattgtt tctttcttca ttatttccgt
    24481 tgttgtgttg cttatgatag gaaaagaagg ttcagagaat tgaatctgac ttaggtcctt
    24541 cgccagtttt tttgctgccg gttctaaaat agctgtatga aaaggcccgc tgacatttag
    24601 agggatcatt cttttgaacc ctttttcttt taatagtaaa acagcttcgt ctactgcttt
    24661 ttcttcgcca ccaatcacga tctgctgagg tgtattataa tttgcaggag atacgatgcc
    24721 gtacttgcta gcttcatgac agctttcctc gatcgtttca atcggcgcat tcatcactgc
    24781 aaccattttc ccgcttccag ctggggtagc ttctgtcata taagcgcctc tttttgctac
    24841 taacgcaact gcttcagtga aggatagcgc attactagct actaatgccg aatattctcc
    24901 taaactcagt cctaaagctg catctgggat gattccatgc tccttcaata agcgataata
    24961 cgcgatgctg actgttagaa tagctggctg tgtatattgc gtctgatcca aacgttcatt
    25021 ttctgtaaag caaagttcag ccatatcgta gccgagaatc tcacttgctt catcaaatgt
    25081 ctgctttaca acggcttctt catataaatc ttttcccata ccttgatatt gtgcaccttg
    25141 gccactaaat aagaatgctg ttttcatgtt tttctccaat atatccagaa tatatgtttg
    25201 attcttccta ttcaaaaagg ccgagacatt cctatttcag gaaatgtccc agcccccaac
    25261 ctaattttaa tgattatgca gtttgttttt ctacgtaagt cactaaatct tgaaccgttt
    25321 tgattccgtc ttctgtttcg attttcacgt caaattcatc ttcaatttca ttgatgattt
    25381 ggaataaatc caagctgtca gcttctaagt cttcttggat gtcagtagtc aatttgattt
    25441 cttcagtttc ttttcctaat tcttctgcga tgatttcttg aattttttcg aataccataa
    25501 taatatattc ctccgatatt gtttgctttt tatttttata atttaacagt ctacaactcc
    25561 atgagaatac ttccccatgt taaacctccg ccatagcctg taaatattac tttctgctgt
    25621 tttcctaagg tgatctttcc actagaaact gcttcatcca ataagatagg gatgcttgca
    25681 gcagatgtat tcccatattt atccatattg gtcaggaact tttcttgcgg catctttact
    25741 tttcgggcaa ttttctcaat aattctgagg tttgcctgat gcaaaagcag ataatcaact
    25801 ggtttgtctt tcatgacttc ttggatattg tttgcaacgt ctcgtacggc aaaatcaaaa
    25861 atatctctgc cagtcatttg caaataatac gaaccttctg aatcttctga atagaacgga
    25921 tttttatttt gctggtagcc agcggtcaat gagctacttc tggtaccgtc agctgctaat
    25981 ttttctttca gcaatttttt ctgtggattc gcttctaaga gaatcccacc tgctccatcg
    26041 ccaaacaaca cagcagtcgt acgatcagac caatcgatta gcttagatag tgtttcacca
    26101 ccaatcacca gtcccttagt tgagccgcag cggatcattt tttcagccat gcttaacgca
    26161 taaacaaatc ctgagcacgc agcactgata tcaaaagcga tagcatgagt tgctcccaat
    26221 ttcccttgta cttgtgctgc tacagatggt gtcgtgtaat cgggcgacat tgttgctact
    26281 aaaataaaat ccaaatcttt agggtttaga tttttctgtt ttatcaattt ttccgccact
    26341 aaaatgcata aatcagaagt ctcctgattt gttacacatc ttcgttcacg aatacccgtc
    26401 cttgacgaaa tccattcatc agaggtatcc atcatcttgg aaagatcatt attagtaata
    26461 atcttttcag gaaggacgct ggctgttgca gtaatcattc caaattgttc cattaaatat
    26521 cctcacttat agtcttgcaa gaagtcgtgc aagtttttca gtgcatccag caaggcatgc
    26581 tgttcctccg tagccattcc gtctaagatg ttcttgacca tttcacgatg aaaatgctga
    26641 tggacccgaa atagtaactt tccttttttc gttagtccca actttacaac gcggcggtca
    26701 tcttcactgc ggatacgttc gacatagcct ttttttacta acttgttaat agcagtggtc
    26761 aaggtcccaa cagtaattga tagttctttg gctacttctg aagttgtttt tttcttgtac
    26821 atcccgattg cctcgatcgt gtgcatctct gtgattgaca gatctttgaa ttgagatttt
    26881 ttcagctcag actcttcgat tgtcaaaata tcattgaaga cactaacaag ataatcattt
    26941 actgttttta aatctggttc catgttccac cgtccactaa ttagtttgat tatcaaatct
    27001 tttgatgttc aaactatatc ttaacttttt tcaaaatgca accttaaaag atcatttttt
    27061 tactatatga gcttttttta agattttact catttaaaac aactgataaa tcagcattta
    27121 taatttcttt tattagaaaa atcatctatc tcacatattt tgattatcaa agtattttct
    27181 gtgaacagaa ctatagaatt ccctaaaact tgtccattat ttcaaaattt gttatagtct
    27241 ttttattcaa agcgtaaaag gagatcctat gttaaaagaa aaaatgaaaa ctctccccat
    27301 gctgccgggt gtctatctta tgaaagaccg agatggtaag gtcatctatg ttggtaaagc
    27361 aaaacggctc aaaaatagag taagcagcta ttttcatcag aataaacagc attcaaaaaa
    27421 agtattacgt atgattcatc atataacaga ttttgatttc gtcgtagtag acacggaatt
    27481 agatgcttta ttgctcgagt gtcaattgat ccaacattac cgtccttttt ataaccgaca
    27541 aatgaattat ttcagtaatt ataattatgt acatattacc aataagggat ttgtattaac
    27601 agatactcct acggctcgaa catacgggcc ttttcgtctc tataaaaaaa tgccgtctat
    27661 tttgcgtata atggaagaaa cttatcaaat gccttggttg tctgaaatta gtttgttagc
    27721 tttgcgagtc cagcttcctg acctacagga aatgactttt gaacagaaaa aaaaggaact
    27781 ccaagggctg tttcaaggcc gaaataaaaa gctactgact tacttgaaaa aaagacaaca
    27841 acatttcatc tatcagttga atttcgaaaa agccggtatg cttcaaaaag atatcgaatt
    27901 agttacttat tttattagac ggatccagga acaaaagcag tttttaagaa caccatcgct
    27961 caccttcagc atgccattag cagcagatga gagtcagaaa aagcactacc tcgtttgtta
    28021 tggtcaactt gcagaaacaa tgattacctc tggtgacgtt tctcctgact tctattatga
    28081 aaagaaagaa gctcatttat ctttgaaacg tcaattgtca aaagaagaaa tcgatcctgt
    28141 acaaatcttg atcagttacc gcaaaaaatt agaaaaagaa cagtttgaaa ttgaactgtt
    28201 aaacaaaaaa gaagctgaaa agcaactaaa ttagttgctt ctcggcttct tttaggcatc
    28261 ttcaacttca aatgtcaatt atcctaaaat ttattggatt aagtcataga tttccatcgc
    28321 tacgatatcg atattatcaa attcgtattg ctgatgagta tctgtttcag ttaattcaaa
    28381 tgtatcggtc gctttatcat aagttactgt acacttctct acgccttctt tttcaaaacg
    28441 gcgaacttgc agttcattat ctgctgactc gaccatagcc tccagtcgtt ttatgattgc
    28501 gactaattgt gaatgtgtca tcggaggtcc tccttttctt atttctgtta tattgtatca
    28561 aaagcatagc ctacttgcat tgattttctc taaaaaaact cgttttttat gatttttttt
    28621 ctggtatttt tccttcaggc caccaaagtt tgatcaaagc ttgggttccg tcattctcaa
    28681 aacctttatc tgccaactct tcatatagtt tcaatgcttg ggtagttgct ggcaatacaa
    28741 gatccatttt ttctgcttct tctaatgcaa tctttaaatc tttgataaaa tgtttgacaa
    28801 aaaaaccagg tgtgtaatct tcttttaaaa tacgaggaga ataattgctt aaagaccagt
    28861 tagctgcact tccacctgaa agcgtctcaa tcactttctt taaatcaagt ccgttttttt
    28921 gtgcatagac aagcatttcc gtcattcctg tcatcgtacc tgcaatcatg atctgattag
    28981 ccatttttgt atgctgacct ttcccagcag aaccatgcaa tgtaaatgtc gtaccaaatt
    29041 ctttgaataa aggcagtact tgatcataaa cggcttcttc tccaccgacc atgatcgtca
    29101 gtgtaccatt ctttgctcct aagtcaccac cggataccgg tgcatctaac gcatctgcgc
    29161 ctttttcttt tgctgttttt gcaatttttt ctgccaggct tggtgtactt gtagtcaaat
    29221 caactaaaat atgtcctgag atatctgcag aaaaaatccc cgactgtcca tagtagattt
    29281 cttctacatc tttggggtaa cctaccattg taaagagaat attactttgt tctgctaccg
    29341 cttttggtgt atctgcccag atagctcctt ctgttactaa aggatcagct tttgcttttg
    29401 tccgattata gacagctact tcgtgtcctg cttctagtag atggcgtgcg acagcacttc
    29461 ccatgacgcc tgttccgata aaaccaagtt tcattttttc gacctcctaa aaatcaaaaa
    29521 tccttgcttc tatgctagta tacgctagaa acaaggattt tttcataaaa aatgtttgaa
    29581 ttttatcttt taaatgaatt taattttatt ttgattcgtt caatcgagtc ttcttcttct
    29641 tttcttcgca tctcttcttc atgataaaca accatgtctt gataaaattc gatcatagct
    29701 tcgccgaaat gtgtagatga aatatcataa agtttagctt ctaaaacttt tggatcttta
    29761 ggaacttcac tggaaatata atcaataagt gctggtgcaa agtcttcgtc ggtttcaaaa
    29821 gttttcccta atgaaggatg atcgaacaat cggttcaaat aagcatttcc ttccacgaca
    29881 caaggtgttc cggctgccat cgcttctgta taagtaagcc cttgtgtttc tgaagtagaa
    29941 gcactgacaa aataatctgc cgctttataa taaagtgcta catcattgtt gtccacttct
    30001 cctgtgaact gcacaaattc ttctaactgc agttctgaga tcaattcctc taactcttct
    30061 acataaggtc cttttcctac gataactaat ctggcgttag gataagcgga gatgacctga
    30121 ggaaacccat taatcaaggc ttggatattt ttctcataag aaatcctgct taaagaaaga
    30181 atcatcaaat ggttttcctg aagacctagt gactccctta atttgctgat atcctgctga
    30241 gtgatatcag aacgtttgaa tttttcaatg tcgataccag taggaatcac gcgaagcggt
    30301 gctattacac catagctgcg taatgtatca ataacacgtt cacttggaca aactacacct
    30361 gtcgtatgat ttgcaaataa tctagacaag tattttacat gggattgcct gatcactttt
    30421 cctttaccga tataatgaag gtagtcttca tacatcgtat ggtaagtatg gatcagaggt
    30481 attttcaact tcttagctac catcttccca agtatccctg ctccgaattc tgtatgggta
    30541 tgaataagat ctagttctag ttctttggca accaaataag cataccacat gcctctaaca
    30601 acaactcttc gatccttgaa agaaataaat ggtacacttg gcattcgaat cacatctttt
    30661 tccaacttat ccgcattagg atcggtcgtt gtaaaaatat agacttcatg cccatgtctt
    30721 tctaattctt gttttaatgt tttgatcgat gtagcaactc cgctgacttg cggaaagtag
    30781 gtatcggtaa aaaagccgat tttcatgttt ttcgcctcca aactagtcct tgacctgatt
    30841 tacttttttt aatttgctag agactttttc attcagtaca ctttcgtata catttttaag
    30901 ttcttcaccg attttattga tacttcgctc ttttgctgtt tgataaccgg cttgtgtcgt
    30961 actcggtagt tcttgattgg taatctgttg gatcagtcgg ataaattctt cgtttgtctt
    31021 ccccatatag cagttcttgc tatcttctaa ccagccatta tacactggaa tatctcgaac
    31081 aagtacgttt tgtttgcttg ctaaagcttc taaaacaacg atcccttctg tctcttcata
    31141 agaagggaaa aagaatagat ctgcacctga atacgcacct tctatgatct ctccacgaat
    31201 gtaaccagga aacaggacat tttcaggatg atcttctttt acaattttcc ggatgttccg
    31261 aggaatcgag tacatgggaa catgaccaaa ccaaataaat gtgtattcgg gcatcttctt
    31321 agcaatttct acgaaatcaa tgattccttt acgttcgaaa aacaaaccga cacaaatgat
    31381 tactttttga tccggagaca gtttgaaata ttctctgaac ttttgttctt tcattggatc
    31441 agggtgatat ttctctaagt cgatcccatt ggaaatagct tgaatcggca cacggatacc
    31501 atagctttcc aacaactgtt ttgaataagg tgttggcgtg atcagatagt ccgctttttg
    31561 gtacaatcct accagatatt tttttacgat aggagaaagc tggttcgatc cgataaagga
    31621 atttcggaaa tcttcctctg tagaatgcgc atgatagaca actttttttc cttctcttct
    31681 ggctttattg accatattat gactattgat tccgtatgta ttgatgtgca ggatgtcata
    31741 atcttctttt tcatctagtg tataagagat accgacttcc gtcagagcac gtttttgatg
    31801 atcaagcgca cgcccgattc cagattttgc aagcatcttt tcactttcaa aatataataa
    31861 taccttcacc ttacgtcccc cttcacttat atagtataac atagcctaca aactgtcact
    31921 caaacttaag ccctattttt gtctattctt actgacaaaa acgttttctt aaaaaagaac
    31981 aaaaaaactg gcgtagctct tttacaagcc acaccagctt ttgatacgtt gtttatttta
    32041 catattcatg aacaagttca acgacttctt ccatcatatc gcattctttc aatgcacgat
    32101 cagcaagttc agccattttc gctgtgtcca agcgtttcat taaactacgc gttttaagaa
    32161 tagatgtcgc actcattgag aactcatcta gacccatacc tactagcaat ggaacagctg
    32221 tttgatctcc agccatttct ccacacatac ctgcccattt tccttcagcg tgtgctgcat
    32281 caattacatt tttgatcaaa cgtaaaattg atgggttata tggttggtac aagtaagaaa
    32341 cgcgttcgtt catacggtct gctgccattg tgtattgaat caaatcgttc gtacctacag
    32401 agaagaaatc tacttctttt gcaaacttgt ctgctaagac tgctgctgct ggaatctcga
    32461 tcatgatgcc gacttggatc gtatcagata cttccttgcc ttcacttatc aatttttgtt
    32521 tttcttcttc aaagatcgct tttgctgcgc ggaattcttt gagtgtagct accataggga
    32581 acatgatacg taaattacca tgaacagatg cacgaagcaa tgcacgcatt tgtgtacgga
    32641 acatttcgtc gccttgttca gataaactga tacgcaatgc acgatatcct aagaatggat
    32701 tcatttcatg aggtaattgc agatatggta gttctttatc tccaccgatg tccattgtac
    32761 gaacaactac aggttttcct tccatacctt ctaatacagc tttgtaagct tcatattggt
    32821 catcttctgt tgggaagtct ggagaatcca tatacaggaa ttcagtacgg tacagaccaa
    32881 ctgcttctcc accattatta tggacaccaa ctagatcttt tggtgttccg atgtttgcag
    32941 ctaattcaaa atgcttgccg tcagctgtga cagtttctgc attttttaat ttttcccatt
    33001 ctgctttttg tgctgcgtaa tctgcacctg ctttttcaaa ttcagctttt tgttcatctg
    33061 taggatcgat gattacatcg ccttcgatcc cgttgacagc caaaatatcg ccttctttga
    33121 ctttagcagt aatttctttt gtcccaacga ttgctggaat ttctaaagaa cgtgccatga
    33181 tagcagaatg tgaagtacgt ccaccaatgt ctgttacaaa cgcttttaca aaattgcgat
    33241 ctaattgtgc tgtatcactt ggagtcaagt catgtgcaac aacgaccact tcttcgttga
    33301 tcattgatgg atttggtaaa gtaacgccta ataagtgcgc taaaatacgt ttagcaacgt
    33361 cacgaatatc tgcagcacgc tcttgcatat aagcattatc ttccattgct tcgaacatac
    33421 cgatatacat atccgttact tcttttagcg ctgattcagc atttacgctg ttgtctttaa
    33481 tattttgctt gatttgacct accatttctg gatctgaaag aaccatcaaa tgggcatcaa
    33541 atacttgcgc ttctgcttca cctaagcttt gcgctgcttt ttcacgaatt tgctgcaatt
    33601 cttcagtaga tttagctaat gcagcatcca aacgagcttc ttcagccgca gtatcttcta
    33661 ctgttgcctt actgaatgtt aaatccggtt gaactagcag gtaagctttt gcaacggcta
    33721 caccgtcact agcggcaatc ccttttagca tttcaaccat tattcagata agccttcttt
    33781 cttcattgtt tcaacgattg ctgccattgc atcagcttcg tcagcacctt ctgcagtaat
    33841 agtaacatca gaaccttgac ctacacctaa agacataacg cccatgattg atttcaagtt
    33901 tactgattta cctttatact ctaagtttac atcagagtta aatttgcttg ctgtttgtac
    33961 taatagtgta gctggacgag cgtggatccc agtttctgct actacgtgaa attctttctt
    34021 ttccatatta atcggtctcc tttaagtgag tgttgttttt atgtgagggt tttctttttt
    34081 agtaattcag agaatcctaa caaatgccac cctttcatct gtaaagatta acattttttt
    34141 tcgttagata caacagtttt cattcaattt cagataaaag tattcaaatt attccggatt
    34201 ctttttcatc cttttcttca cattttataa caaacgtgtt tatttccttt ttcttgtcgc
    34261 tttctcttct cctgacgttt atcattcttt cctttgaccc tctttgtttt catatgaaac
    34321 gaattacttg cttccctttt tatttttagt ataataagag tcaaaggtca ggaatggtca
    34381 atagagattt caccttttct acctcataaa tctcttaaaa aactaggggt tattctttta
    34441 cctcatgaaa aacgagatgt aaaatatgga tgtacccatt tttgtgaaag gacgtgaatg
    34501 attcatgctt tgtcaaaact gcggcaagaa tgaggcaacg attcacttgt atgccactgt
    34561 caatggtcag cggacacaac tcgattactg tcagagctgt tatcaaaaaa tcaaaaatca
    34621 acaaaatgga ggtctgacta atatggccca aaatgatcca tttggatttg gcagtttgga
    34681 cgatcttttc cgttccatgt ctcgccaaat gcaacagcaa ggaaattatg agcaaacacc
    34741 accaacacaa tttggcggaa acaacaactt caatggtggt cagccacctc aaggcaatac
    34801 agaaggttta ttgggagaat acggaatcaa tatcacagaa caagcacgac aaggtgatat
    34861 cgatcctgtg atcggacgcg atgacgaaat caaacgagtc attgaaattt taaatcgccg
    34921 aaccaagaac aatcctgtct tgattggaga accaggtgtt ggtaaaacag cagttgttga
    34981 aggtttagca caaaaaatcg tagatggtga tgtaccgcaa aaattaatgg acaaagaagt
    35041 cattcgttta gatgtcgtat ctttagtcca aggtactggt atacgaggac aatttgaaga
    35101 acgtatgcaa aaattgattg aagagatccg tcaagcagaa aatgtgatcc tattcataga
    35161 tgaagttcac gaaatcgtcg gtgctggttc tgctggtgat ggaaatatgg atgctggtaa
    35221 tattttaaaa ccagctttag ctcgaggaga attgcaaatg gttggtgcta ctaccttaaa
    35281 tgagtaccgc atcatcgaaa aagacgctgc tttagaacgt cgtatgcaac ctgtacgggt
    35341 agatgaacca actgtcgaag aaacgatcag tattttgaaa ggtttgcaaa aacgttatga
    35401 agactatcat catgtaaaat atactgatga ggccatcgaa gcagccgcaa ctttatccaa
    35461 tcgttacgtc caagatcgct tcttgccgga taaagccatc gatttgctag atgaaacagg
    35521 ttctaagaaa aacttgacga tccaaatcgt tgatcctaaa acaatcgaga aaaaactgca
    35581 agaagcagaa gaacaaaaag ttttagcttc tcgagaagaa gatttcgaaa aagcagctta
    35641 ttatcgcgat cagatcaata aacttcaaaa aatgaaagaa cgtcagctca ctgaagagga
    35701 aacacctgtg attaccgaaa aagatatgga aaaaatcgtt gaacaacgga caggtattcc
    35761 agtgggtgaa ttaaaagaaa aagaacagac acaactgaaa aacttagcag atgacttgaa
    35821 agctcatgtc atcggacaag ataacgctgt agatcgagta gcgaaagcga ttcgccgaaa
    35881 ccgtgttgga ttaaacaaac agaatcgtcc aatcggctcc ttcttatttg ttggaccaac
    35941 tggtgtaggt aaaacagagc ttgcgaaaca acttgcctac gaactattcg gttcacaaga
    36001 ttcaatgatt cgtttcgata tgtctgaata tatggaaaaa catagtgtct ctaaattgat
    36061 tggttctcct ccaggttatg tcggatacga agaagctggt caattaacag aaaaagtacg
    36121 gagaaatcct tacagtcttg tcttgttaga tgaagtagaa aaagctcatc cagatgtttt
    36181 gcatatgttc ttgcaaatct tagatgatgg tcgattgaca gatgcacaag gaagaacggt
    36241 cagctttaaa gatacgatca tcattatgac aagtaatgcc ggaactggta aagtagaagc
    36301 aaacgttggt tttggtgcgg cacgcgaagg tgttactcgt tctgtattga accaattaaa
    36361 caactacttt acaccagaat ttctgaaccg ttttgacggg atcatcgaat tcagtgcatt
    36421 atcaaaagaa aacttgatga caatcgtcac actaatgcta gacgatgtca accaaatgct
    36481 ggcagcacag caacttcaca tcgaagttcc tacgaatgtc aaagaaaaat tagttgactt
    36541 aggctatgat ccatctatgg gtgctcgtcc tcttcgacgc acgatccaag aacaaatcga
    36601 agatggtatc gctgaatttt atcttgatca cccttctatc catgagttga aagcaaaact
    36661 ggataaagat ggaaaaatca tcgttacttc taaaccagaa cgtttggcta aagaatcagc
    36721 cgaagaaacg gctgaataaa tccagtttta tagcgtgaga cggtatttct ttgagaaatg
    36781 ccgtctcatt cttttttcag aaaagtcaaa atactgttca ttttataaaa aagaaattat
    36841 aataagagaa acaagcaatt aaaaatacat aaaagaggtg agcgccatga aattggtaaa
    36901 tgtaacaaac agccattccc gtcttgtatt aaaccagctt gaaaacactg atgcccatct
    36961 agtcaaggtc tacacagccg gaaataccac tattgtctac actgaagccc ctgaacataa
    37021 tgaaattctg ctgatcaatg acaaacgtaa aatccagccg aaagaaatcg aagatgctaa
    37081 aaattatttc ttagataaaa tcaaagacgc cgtttaccac gaggatgaaa tcaaagtaat
    37141 cgaattggca ggccttgttg aaatctcgat tccaaaacat gaattaggcg ctacattagc
    37201 cgtgtaaaca aattttgaac ataataatta aagagcgtgg gacaaaagta aagaacactt
    37261 ttgtctcacg ctctaaacac gtataaacgg cgaaagcaga agcaactcct tcggaaataa
    37321 gctgaaattc acgaaaattg cttttcaaat ttttgtgaat tccagcttat ttcttggagt
    37381 taaacgcttc tgtctcagcc tctttttctt tctagctttt tgatttttct cttttctttt
    37441 gtacttttct cttttcattt tcagttctac gcgtgtcttt atttttaact ttttcctctt
    37501 tatggatgat tgatcgtact ttttgtgcaa tttgctcgtt tttgtcccag tcttttacat
    37561 ctaataatcg acataatcgt aacatctctt cttttttctg tttttttctt tcacgtcttt
    37621 gccattctgt ttccatgtgt cacactctcc tttctttaat catatgtacg caaaataatt
    37681 tttatatttt tttgattaga catttctatg attttaatat agtaaaaaga gccgtcacgg
    37741 aaaatccgtc acggctctaa acaaaatatg agaggctgtt tttgtttggc tattcttatt
    37801 acttgatgca gggcagcttg tgtcaagact tctttacatc aaacttttta attttacatt
    37861 gggatattta tccgcaaacc agcgttctgc aaattggttc tcgaataaga acaacggttg
    37921 gtcgaaacgg tcacgagcca agatattgcg acttgaactc atcttctcat ccaaatcttc
    37981 tggatcgatc cagcgagcga ttttgtgtcc cattggagac atgattactt cggcgttata
    38041 ctcatttaac atacgatatt ggaatacttc gaattgtagc tgaccaacag ctccaatgat
    38101 atattcttcc gttagatatg ttttataaag ctgaatcgct ccttcttgaa ctaattgata
    38161 gattcctttg tggaaggatt tttgtttcat gacatttttt gcagtcactt tcataaacag
    38221 ctctggagta aatgaaggga gttcttcata agcaactttt agttttcctt cgaacaatgt
    38281 atccccaatc tgataattgc ctgtatcata tacaccgatg atatcgcctg ctactgcttt
    38341 ttcgacgttt tctctcgaat ctgccataaa ttgtgtgaca ttgcttaatt tcagtttttt
    38401 atttgtacgt tccaaccaga catccattcc tcgttcgaat gttccagaac agattcggac
    38461 aaaagcgatt cggtcacgat gggctggatt catatttgct tggatcttga atacgaaacc
    38521 tgaaaattct tcctcataag gacttaccat ctgatcatct tgtgttttgt gtccataagg
    38581 agctggtgcc aattcaacga aagtctctaa aaaagtctgt acaccgaagt tagtcaatgc
    38641 agaaccaaaa aatactggtg tctgatcgcc acgagcaatt ttttcttgat taaatgcatc
    38701 tccagcctct ttgattagtt ctacttcttc taagacttgt tcatataagg aattttcagt
    38761 tagaggatga ttttcgggaa gcagtccatc ttcatccaat tctactaatc gttcatcctg
    38821 ataattttcc ggacgataaa actctacacg attatggtag atatcataaa gaccttctag
    38881 ccctttaccc ataccgattg gccaattcat cggataagat tcgatatcta atagctcttc
    38941 taattcttct aacaattcca atggttcacg accatcacga tctagtttgt tgataaaagt
    39001 aaatatcggg atgccacgtt tttttacaac ttggaataat ttctttgtct gtgcttcgat
    39061 cccttttgca ctatcgatta ccatgaccgc actatccacg gccatcaaag tacgataagt
    39121 atcttcagaa aaatcttcat gtcctggtgt atccaagata tttactcgtt tcccttgata
    39181 atcaaactgc ataacagaac tagtaacaga aatcccacgt tgtttctcga tttccatcca
    39241 gtctgatttg gcaaaattac ctgttttttt gccttttacg gtcccggctt gacggatagc
    39301 cccaccaaac aatagtaatt gttctgtaat cgttgttttc ccagcatccg gatgggaaat
    39361 gatcgcaaaa gttctgcgat tgtccacttg ttgctttaat tttggattat tcataaccta
    39421 actccatttc ttccattcaa ttatttatat tttctctagg cacagattgt ccgatctctt
    39481 aaagaaagac aatttcatat agggctgtga caaaagccgt gtagcagtct ctttttccga
    39541 gtaaacggcg ttctagagac agcctatcag caataagccc acccaagcca aaaatacgaa
    39601 aagctgtttt tgcttggctg ctcttattac ttaatgcagg atagcttttt cacaaccttt
    39661 gtcaactact acaactgaat cagtatagca tggattcagc gaatgaaaaa gccaccaaac
    39721 cataagagtc aaatattttt ttgtcagctg actaaaagaa aagacgtgtt gcttgtttat
    39781 tcaagcaaca cgtctttcat aaccaagttt ccaattatct tcttggctcg tcatcttcga
    39841 attcttttct gaagtatctt cgttcttctt caggttccgc ttctgtttct tccggatcat
    39901 gaaaaatgac acggatttta aggattcgag aaccttccat ttcttcagaa accagcgtaa
    39961 tattatcgac atcaaacgat aacttttcgc cttcatccgg aatcatgcct aatgctgtaa
    40021 tcaaataacc agccatcgta tctacatcac tcatatgcag atcactgtca aaagcttcat
    40081 tgaactcatc aatcagcata cgtccttgga tgatatattc gtgttcatcg attttttcat
    40141 aaagattctc aacttcatct gattcatcat cgatttctcc gacgatttct tctaaaaggt
    40201 cttctagtgt tgctaaccca acgacgccgc catattcatc taataaaata gccatctgat
    40261 tctgcgtctt tttcatttca tataacagat catcaataaa gaccgtttca ggaacgaata
    40321 aaggctcctg catgattttc ttgatatcta aattatcaaa gccgaattta tgggcagctt
    40381 ttagtaaatt ctttgtatga aggattccga ctactttatc tttgtcttcg ttataaacag
    40441 ggattcttga atagttttcg gataaaactt cattcacatt ttcttccaca gtgtcgttga
    40501 tatcaatcat aaatgcatcc gttcgtggga ccatgacttc tcgggcaact ttcgtatcaa
    40561 gagaaaaaac cccttggagc atttctaatt cttcattatt caatacgcct tcgttttcaa
    40621 gcatataacg catttcatct ctggtcattt ttgaatcttc atcatcaaaa gtcatcggcg
    40681 tgatacgcgc caataaactt gtggaagcag aaagcagcca gacgaagggc ttagctacta
    40741 caccaatcaa gcgtatcagc cctgaagtga actttgcgac ttcttctgat ttatttaaag
    40801 caatacgttt agggtacaat tctccaaaaa caatcgatac ataggtcaaa atagccagca
    40861 caatgatatt tgcaatattt tttgccgctg tgccgccacc taataccgga gctaaccgtt
    40921 ccgataaagt attagctagt gaagcaccag acaaaatgtt gaccaaagtg attcctactt
    40981 ggattgtcga taggaaatta tttggattct gcaatatttt taaaagcttt tgagatttca
    41041 catctccttc atcagctttt tgctcgattc gattcttatt gatcgaaaca acagcaattt
    41101 cggaagctgc taaaaaagca ttgatcaatg tcaaaacgat caataataaa atctgcgcta
    41161 acagcgactg actctcaggg tcagcattca taatcgcatt ctctccttat aaaattaatt
    41221 tttagtttac gatagaaaaa aacgtggcac tatagccacg ttaaaatggt atcacaaagc
    41281 aattttcttt gcaataaaaa caagtgtact aaaactacct acgaggtcgt agcaattttc
    41341 ttcttgtttt cattttgctt gtcttctttg acgattttga ttatatagga aatgatcgtc
    41401 ttgcagattg cgtaaaaagg aacacctaag aagataccaa gcaatccggc aatatttcca
    41461 gctactagaa gaacgataat gatcgttaat ggatggattt tcagtgattt cccaattaca
    41521 ttaggataaa tgatattccc atccaactgt tggacgatta gcacaaccac acaacaaagt
    41581 aatgctttta ccggatcatt gaagactgtt actagaaatg caggtgctag tcctagataa
    41641 ggtcctaaat atggaattag gtttgtcaat cccgcaatga ccccaaataa gaaagcataa
    41701 tccacaccaa ttaccatata tcctaaaaat gtgaaggtac caacgaataa acattcgatt
    41761 gcttgtccgc taatgtaatt agccaatgtt ttattcagtt gccccaataa ctccacaatt
    41821 tggtttcttc ttttttctgg gaaaaactgt tggatgtttg gcactagttt ttctccgtct
    41881 ttcaacatat agaacaagat gaatggtgct gtaatgatta ctacggttgc cgaagcgatc
    41941 gttccaacga tcgaacctaa actattggat actccactaa ggaattgctg aatgattgtc
    42001 ccgtaagaaa tgtctaattg ctcaaaatat ttattgatat ctacttcctt gaacaaaggc
    42061 aattcggcta cctcttttaa ccagctttct acctgtttga tgaaatcagg catattagat
    42121 gccaatgagg aaatttgctg tactagactt gggatgacac taagtaaaat ccaaataatt
    42181 gctgcaacta aaaggagcag cacaattgcg acagcccata ttcttttgat ttttgctttc
    42241 atcaacagct tgacaatagg attcaataaa tagtaaagaa agcctgcaat cagtacaggt
    42301 gcaaataacg tggaaaaaaa tgtcccgatc ggttcgaaaa taaagtttat ttctgatgaa
    42361 atcatgatca atgcagctat gatcaataat tcaagcgacc aaaacattag tttagactgt
    42421 ctaagttttt caaacaatag atttcctcct ttctttctta ctagtatata ttatattcgt
    42481 taaaaattct tttattcttt ttttattttt gaaaacttgc catacttttt atttgtttta
    42541 ttttccagta tactatacga aaggaaggtg gctagaccat gaaagttgta caaacaaaag
    42601 atacaatgag caatatttac ttagatgctg tacggatcag gcatcaagtt tttgtagtcg
    42661 aacagggtgt gcctttgtct cgagaaatag acaaagatga agcccattgt atccacttcg
    42721 tcctgtactc agataaaaaa gaaccgcaag gaactgtacg tcttttgcct ttagaaaacg
    42781 gaaaaatgaa attacagcgg atggcgattc tttctgaata cagacaccaa gggttaggaa
    42841 aaatattgat tgaagaagca gaaaactttg ctaagaatca aggctataat acgattttat
    42901 taggggcaca gtccacagct gaaacttttt acgaaaaact aggatataca gcttacggcg
    42961 atccttttga agatgctggc atgcctcata tttatatgaa aaagacttta taaaaattta
    43021 tttcgaaaaa agcaaaaaac agcaagcttt tgagaaaaat ctctcactgg cttactgttc
    43081 ttttttgtgt ttacttacgc gacaattgct tgtaacggtt ataccaaata tcaatatagc
    43141 cttccgagaa cgggccatct ccattattga tccagtcaac cagaatcttc acattttctt
    43201 ttaggatgaa gtcaatatcg ttcgggtaat tcatcatttt gctgtgcatc tcatattcat
    43261 cgacatccaa tagtcgtttc tcgccgtcag gaaatacctt gatatccaag tcatagtcga
    43321 tatatttcaa ggcctcatcg tccagcaaaa aaggtgaagc tagattacaa taataggaaa
    43381 cccccttttc tctgatcatt gctattacat tgaaccagta ttttttatga aaataaacaa
    43441 tcgctggttc gcgcgttacc catcggcgtc catcagattc agtgactaat gtgtgatcat
    43501 tcacgccgat catagagtgt tcgcttgttt ttaataccat ggtatctcgc cacgttcgat
    43561 gcaatttgcc gtcgtgcttg taactttgga tcgtcacaaa ctctccttct tttggaactc
    43621 ccatagcaac ccttccttaa gcagcatttt gtgctttgtg tttgggtgtt cattacaccg
    43681 acatcataat tattatatca ataaaaatga gctttgccta gaaaggattc ctattgtttc
    43741 gatttttctc taactgatct accagtttca tttggacctt aggaaaaacg accgaatcaa
    43801 atgcatcagg cttcaaccac ttcgaagttt tgttctcggt aaattcttgt tctgctccct
    43861 cggttgcccg tccgtaaaaa aggagaacat gccatttcag atgactaaaa atatgagtaa
    43921 cttctcctaa atgtcgtgtc tgccaaacaa agagttcctg cttttcaaat gggagatttt
    43981 gctcttcttc tgctactagg tcatcaaaca gatcgatttc tggctttgtt tcccattctt
    44041 ttttcaatcg ctcatactcc tcttgtgtca cttccatcat tggaaatgtc cacatattcg
    44101 ccagcaattt ttggctatct ctttcttcaa aataatacgc tccagaatga ttttgaagag
    44161 ctgcactgat ataataaacg tcttttggct ttgctttttt tgtttttaca ggaaaactcg
    44221 tttggattcc tcgtttgtta gctaaacaaa aggcttggat cggacaagtc tcacactttg
    44281 gagaagttgg tgtacagata gctgaaccta gatccatcat tgcttggttg aattcacctg
    44341 gatgcttttc atcaatgatt ttccgcatcg cttcatcaaa gattttcctg ctagaagctt
    44401 ttgcgatgtc tgcttcaatg caaaacaatc tgctgactac tcgcatcacg ttgccgtcaa
    44461 ctgcaggttc tggaagtcca aatgcgatac ttgcaatcgc gcctgtcgta tatggtccta
    44521 ttcccttcaa tgagctaatt tcttcaggcg tttgcggcat ttccccatca aattctgaca
    44581 tgatctgttt agcagcagct tggatgttcc gggctcttga gtaataacca aggccctccc
    44641 atgcttttaa aagcttttct tctggagcat ttgctagctc ttcaattgta ggaaaccatt
    44701 ccatgaaacg ataaaaataa tcgatcactg tgtctactct ggtttgctga agcatgatct
    44761 cagagatcca gatacgataa ggatcacgat tatagcgcca aggcaggttt cttttttctt
    44821 gttcatacca ttgaatgaac tgatcttgaa attcttttgt ttctttatct gtccattttt
    44881 cccattcttt attcactttc ctcttccttt tccgtaatga atcgctggat catatccaaa
    44941 tcaaatcctt tttgatataa gctttgcttt acttttagat ttcttttttt aggttcaaac
    45001 cttaaatttc ttcgccatag tttatctcct tgtttgacta aataatcata ttctatttct
    45061 tgatctgctt cttgcggaag atcagctatc gcttgttgga tcacttcttg agaaaagcct
    45121 ttcgtcatca atgtttgttg gatttttctc aataattctt tttggctttt tccgtgattt
    45181 tttccaaacg ctttttcggc tgtctgatgt gcattttgaa cttggtcttc aaatgtatat
    45241 tggctgagcg cttgttcaat gatttcaggt ttcaaacctt tttgctgcat ctgctgcgct
    45301 aatttctttg gtcctttgtc acttaagcgc atattcgtgc gcacataact ttccccatag
    45361 accaaatcat cgacaaggtc caattctttt aagcgggcta cgattttatt tcgatcttct
    45421 tgaaggattt ccttttcttt taagtatgtt cggatttctt tttccgatcg caactgataa
    45481 cttaagtaat tcattgctag gtgaaaaccg aaatcagctc cgctactctt cttgatctct
    45541 tggatagttt cttcgtctaa ttcccgtcct tttaataatc gatagcgtac taatacatct
    45601 tcagatactt gtaaagcttc tccttcagat aaatctacgc gatagaaagg gcctttgcct
    45661 ttactgattc tcgtaacggt taacataaac atcctcctcg aacatatatt ctctatcata
    45721 ccacagaaaa tccccgtaat caggtattat atgttagaat aaaccacaga aaaaagaaaa
    45781 agggagatac ttatggcaga aacaattgtc aaaactggac aaacggttcc tttgaaaatc
    45841 aagcgtttag gcataaatgg tgaaggaatc ggttatttca aacggttgat catatttgtt
    45901 ccatatgcac taccaaaaga agaagtacta gtgaaaatca cgaaagcaac tcctcgctat
    45961 gcagaaggag aattaataaa agtcaaaaaa acaagcaaag atcgcgtagt ggcaccatgt
    46021 cctgtttact atgaatgcgg tggctgtcaa ttacaacact tagcttatca agctcaattg
    46081 gattttaaaa aggatctgct tttgcaagca ttggaaaaat tcaaaccagc aggctttcga
    46141 tcttatcaac ttttgccgac gatcgggatg gatgagcctt ggcattatag aaacaaagca
    46201 caatttcagt tacgaaaaaa taagcagact caaaaaattg aagctggttt atacgaagca
    46261 aactctcatc agttagtccc tataacagac tgcttggttc aagaacctcg aacacaaaaa
    46321 gtaatgaata ctgttgttca actattgaat aaatttgatg cacccatcta tgatgaacgg
    46381 acaaacagtg gaatcttccg cacaatcatg gttagaatcg gtgttaaaac tggggagtta
    46441 caagttgttt ttattactcg cagtaaaaaa ttcccgcaaa aaaacgcaat gatccgtgag
    46501 atcaatgaac gactgcccga agttgtttca atcatgcaaa atgtccaggc acaaaaaacg
    46561 tctctcgtga tgggggatga aacgatccac ttatggggaa aagaagccat tgaagaacaa
    46621 atcaatgaag tgactttcga tctttctcct cgtgccttct ttcaactcaa tcctcagcag
    46681 accgaattgc tttatggcga aggaatcaaa gcattagatg tccagcctaa tgaaacgatc
    46741 gtggatgctt attgcggagt tgggacgatc ggcttaagtg tagcaaaaca agccaaagaa
    46801 gtacggggaa tggataccgt tcctcaagca atcgctgatg caaaaaaaaa tgcggaaaga
    46861 ttaggatatc acaacactcg atatgaagtc gggacagcag agcaagttct gcctaaatgg
    46921 ttgaatgaag gttttcagcc tgatggtatc atcgtagatc caccacgtac gggtttggat
    46981 aacgcattga tccaatcatt attgaaatac cctccaaaaa aacttgttta tatctcctgt
    47041 aatgtttcta cacttgccag agatctggtt aatttaagta aaaagttcaa gattgaatat
    47101 ttacagtccg tcgacatgtt tcctcagact gcacgttgtg aagttgtcgt gaagatgacg
    47161 agactcgctg actaaatgaa agaggttgtg aaaaagtctg ccctgtatca agtaataaga
    47221 acagccaaac aaaaatagct cttcatgttt tatgaatact gtacttgtga ccgaagagtt
    47281 aacaggagga cactatttat ttaaaaaaag ggttgtgaca tagtttttgt cacagccctt
    47341 tttgattatt attggatatt cacgtctatc acttgataaa atgcatttgt cgtatcgctg
    47401 atattccata ctgctaaaat cacattatat ccttttcgat cctgcggaag tgtgatcgtt
    47461 tggttgactg tttttggtgg aacagttgct ttgtcgtcta tttttgtgat caattcaaaa
    47521 tcactaaatt tcaaaggttg attaggattc caagttggtt tggtaatgta gtaatcccaa
    47581 gtacttgtcc gatgttgtgc tgttaaattc caagtaatat ttaatgttcc tggattaacc
    47641 atgtttttat gccatctgtt agatgtctgt tcatctaaag gctcaaagcc gctgactcct
    47701 gcactagcaa tttttccatc aatgaatgta tttttggtag cttcgatact ttgcggttcc
    47761 cattgtgctc ttccgacatt ttgatttaag tttcctgctg ctgatgttcc taggtatgca
    47821 cggcttcctg gagaagtaat ataaccatgc gcaaaacctg gaatgctaaa accgaacaac
    47881 cctaaactaa ctaacccaat aaacaataac gtactaatct ttttcatgta gaaacctcct
    47941 tcatttgata accacattgt aaacgcttta ttgtattaac acaaacatta tgcttttata
    48001 attttatgtt gaagtaaaaa aggtgaaaaa agtaagatgc agattataac agaagtagac
    48061 gagaaaagta caaatagaaa acatgagaat caaatcatat gatctttttc aaaaacatca
    48121 ttcatataaa caaatgttca actttttaat aacaacaatt atcaattttt ttcttacttc
    48181 acaaactaaa tacaggtctt gctgtgagcc ttcatggtaa actaatatta tagaaaggag
    48241 ttagtaaaat gaagatgata aaagatattc gtttttgggt ttgtgttata ggaattgtca
    48301 tattaggctt tttatcaggg ttgcttagcg gaaatcccgg aaaatattac tattctttgc
    48361 aacttccacc atttgcacca cctagctgga tatttgggcc gatgtggacc ttactgtata
    48421 tattgatggg tatttctctt tatttgttac ttaatcacaa caacaaaaaa cagcgaaaca
    48481 atcttgtcgg tctttttgtg attcagttca tttttaattt tatatggtct gctctatttt
    48541 ttaatttaag aaatattttc attgcagcaa tcgatattac acttttagtt attttcttgt
    48601 cagtgcttat gtatcagttg tggctgcatc atcgcctggc aatgtggctc atgattcctt
    48661 attatttatg ggtactattc gcaactctat tgaattattc aatttatttt ttaaactaag
    48721 cgctaaaaag agacgtcctg taatttaaca catagaaaaa gtgccaccta agttagattt
    48781 tttgtctaat ttaggtggca ctctttatta accaaactat ttttttctag tacccacttg
    48841 ttgttccata ctcattattc tggtcataac cataaccatt ttgttcctgt ccagcgtaag
    48901 gatcataact ttgagtatct tgacttggtg tatagtactg acttgtatct tctgtttgct
    48961 gataataggt attcggatct tggtactgat catatgtgtt ttctgaatag gaagaataat
    49021 cggtgtaccc ttcactattc gatccatcac cgtttgtcga atcgccatct tccgaatcat
    49081 caaagaacat cattgaagca ttctcatttt tcaaattagg taatgtatcg cttgttttta
    49141 tatttaattg tttcttcagt tcattttgga tcgaaagaag atcatttttt cctaaaattt
    49201 gatagtagat atcattgatc atttgtcctt cgccttgcaa ctggtcttgt ttgattgttt
    49261 caaacgccgg ggtgtagttc gtcgctacat caagcatgtc atcccaatct aagtccgtcg
    49321 tcacattgtt ctcaactgct tttaaaattt ttctataatt gcttacgcca tctaaactta
    49381 aaactttatt gacgattttc gtcactactt cccgctgacg acgttgtcga ccgatatcgc
    49441 cttctggatc ttcgtgtcgc attcgagaat aggctaaacc tttttctcca ttcaatgttt
    49501 gttcacctac tggtacatgg acaccatcca aagtaaagtc aattttatta ttcactttga
    49561 tgccaccgac cgcattgatc aaatcttcca tgccatccaa attgatcgtt acataatgat
    49621 caataggaat atcgagcagt tgctcaattg aatccatggc catttcgaca ccaccaaatg
    49681 cgtaggcatg atttaattta tctaccgttc cataacctac gatattcgta taaatatctc
    49741 ggtccaaact gatgatcgtt gatttttttt gtttcggatt aactgttact accatcatcg
    49801 tatcagaacg tccttgttcc gttcttccta atccaccggt atctaaacct aatagcaaaa
    49861 ccgaaaaagg ttctttgtca tcaatgctta ctctctcaga acgtttggag gatattcgat
    49921 tagagttttt agaaattttg tttactgttt ggctcgcttc tcccataaat ctgattccgt
    49981 atgctgataa tccggcaatc agcaaaacga atacccctaa caaggttaat agaacttttt
    50041 gccatcgctt cataatacac ctctgtttca cattttctaa aatattgtct catataactg
    50101 ttcaatcagc aaattcactt tttaatcata agaaaacttt aaaaaacatt tttgtgtaac
    50161 gattattatt ttttaaaatt tctcaaaatt cttaactatc ataccatacc gtgaaaaaga
    50221 tcgaaagacc gaatacacgc agttcgcaat cgttttatct ttttttatgt attttttcca
    50281 gaaaaagcga acaacaaggt attttccaaa taatcgtgca gtaaaatgat cgcacatacc
    50341 tttcccatct ttttaacagt ctttgcctac cgttcagatt atcattcgat ttcacgacaa
    50401 tttcttccta tgactggtcc ttttgttaaa cccatcttct attcgtttta tttccagctc
    50461 actgcatggc tcttaaaatg actcgaacta gtgattgcat taccatcatc ttttaatgga
    50521 tagatatgct cctcttcaaa gtaaaacgat tttcttttaa agtaatagaa ttgacatggt
    50581 aatgagtatg tatactagtg gtttcacaaa tggtctttta ttcaacatcc aaaaactgaa
    50641 atttctttaa aatccattac taacgaagaa aatgttcctt gcttgataat tagttaggac
    50701 atgtcaagtg aacaaatgca tttacttagc caaaaaatct aaaaacttca taaatagaca
    50761 aaaagacacg actctctaag aagtcgtgtc tttattcaac aaattattat aatttagtca
    50821 cttcagcagc ttgaggtccg cgtgcacctt caacaatcgt gaattctact tcttgacctt
    50881 cttctaggct cttgaagccg tctccttgaa ttgctgagaa atgaacaaat acgtcatctc
    50941 cgccgtctac tgtaataaac ccaaatcctt tttcattgtt gaaccattta accgttccgt
    51001 gttccataaa tgtatatcct ccaaaaaagt tcttgcaagt aaccttgcaa gaacattata
    51061 cccaatttag aaaacgctag caagctttcg ctcttttatt ttccaaatta tttttaagac
    51121 tgatatgacg gaggaaatgg ttattttgct gcttcgaaac gtttgtttac ttcatcccaa
    51181 ttaataacat tccagaatgc tgcaatataa tctggtcgga catttttata tttcaaataa
    51241 taagcatgtt cccaaacgtc caaacctaga attggtgtct ttccttccat caatggagaa
    51301 tcttgatttg cagtagaggt aatagctaat tttccatttt ccattacaag ccaagcccat
    51361 ccagaaccaa atcgtccagc ggctgctttt ttgaattctt ctttaaaaga agaaaaatca
    51421 ccaaaagctt cattaatcgc ttcttttatt tctcctgtag gttcgccacc agcatttggt
    51481 gccatgattt cccagaaaaa tgaatggtta gcatgtccgc caccattgtt acgtacagct
    51541 gtcttgatat ctgttggaat agcgtccata tcagataata attcttctat tgttttttcg
    51601 cctaattctg ggtatttctc aattgctgaa tttaaattcg tcacataagt attgtgatgc
    51661 ttatcatgat gcagatgcat cgtttcttcg tcaatataag gttccaatgc gtcatatgca
    51721 taaggtagat ctggtaatgt gtaagtcata aaaaaattcc tcctcaatgt tttcttaata
    51781 atgtctacat tacaaagagt aacaaagaga aggaaattct tcaattgtta tgcctagtcg
    51841 tctttttcac tttgacctac ttcttcttca aaaacctcag tttctttaaa aataaacaac
    51901 ttgctgaaaa tatagttcgc aaggataaca ataatttgag tgatgatttt cgccacatac
    51961 tcattgctgt tcataacatt gatcaacaat accattgccc ccatgtccaa tccgtaagaa
    52021 aggatacggt agaagaagaa cttaccgcat tcaataagtg catgtgtaaa attcggtgat
    52081 tttgaatgga atacccaaag tttgttcgtt acaaaagcaa acaatacaga acaaaaccac
    52141 gaaatagaat tggataaggc catacttaaa tcaaaatatt ggcgtgcgag agcaaaacta
    52201 acaaaattta caatcgtagc caaaccacca aaaaagagat agactagtat ctcccaatat
    52261 ccttttgctt ctaaatatcc ttttaactgt cgatactgct tcatgagcca acctacctta
    52321 ttaaaaattc ttatttatca tactctatat ttcaataact ttcatcttta tttaaaaaaa
    52381 ttaatttttt ttgatccttt gcctttgtct ctgcttggat cgtcacatgt gtaataccat
    52441 attttaattt taataaagaa attatacgag gatatatctt ttcaatctcg cttagtagct
    52501 gatcttcaaa atcaatatgt ccgtcgaaaa taattatctt ttcgctatac tgccaaatat
    52561 ggacatgatg aacatccttt accccatcga ttgcttcaat ttcttgttcc attttttcat
    52621 agtcgatagc aggtgcactt tgtatcaaaa tagcggcagc ttttttgatc accattatcg
    52681 cttctatcaa tatatatatc gaaatgatca gtgtaataac tggatcgatc cagtagatat
    52741 cgaaaaaacg gatcaaaatt gctccgataa tcacacttac cgaagacagt gtatcactta
    52801 acaaatgcaa ataactagat tttatattca aactttcatc tgcttcttgt cgtaataata
    52861 atactgagaa caaattcgcg agcaatccaa taactgctac tgttagcatc aaatgactat
    52921 ttatcttttc tggtgaagtg aaccgcttga atgcttcaac ggttaaaaac aaggataata
    52981 tgatcaatat gaatgagttg atgaaagcac tcaatatttc taaacgctgg tagccatacg
    53041 tacgtttttt atttgcttct tttcgggcca ttttttgtgc cccgtaagaa aaaataattg
    53101 ccaatgtatc actaaggtta tggaaagcat ctgaaacaag agacaaactc cctgacataa
    53161 tccctccaat aaattctgat aaagtgatca ccgcattcaa aaccactact ccaaatagtt
    53221 tttttgatga tctctgtggc tgtgtaggca ctattccttc ctccatttta tttatattgg
    53281 atagtcttta gacaagaata acattttttt gatatttcac caatcattca gctgtttcct
    53341 taaagcactt gtatttcact tgatacttcg ctagaattgc aagtgatgac actactagat
    53401 gaggagtact tatgacaaca aaacaattaa ttatcagttc ctttatacga ttcaaagacc
    53461 taaaggaggc gagaaatgtc ccattttgga aagccattgt ctatctttta gttttgagta
    53521 taattatggc tttgccaatc tcttttcaag tttttcaagt cttaaacaac attcaattgg
    53581 atgggcaaaa gattgctact cgcattcctg attttacaat ccaaaacggg cagcttcaaa
    53641 ccgaagaaaa agaaggattc atttaccaaa caaactccat tatcttcaca tttgatccag
    53701 agggaaaacg aacagaacag gacatctcta ctgatttgat ggggaatttt gttagtgtcg
    53761 ggatgttaaa aaacaaactt atcatagctc ttcctaatac aggcacgact tctgctttgt
    53821 tgaacaataa ccaattagaa cttccctaca ccaatgaatc tttaaaaaac ttaacaggta
    53881 agcagctccg ttctttttta agtgaagcat ctataccact ttggataaaa gtcctgacat
    53941 ttatattttc tatttatcct agttttctga atctgctgat cactttgcta tttaccaaca
    54001 ttgctgcttt tctctatgca cgctttcgac taacaaaagc tacttttctt gattgtttaa
    54061 aaacattgat ctattcaatt tcattgccta ctataattgc aacaatcttg atggtctttc
    54121 ttccttcttt tgacactagc gccttcattg cttttgcagg aatctttatt tttgctcaag
    54181 ctgtcaaagg atgggcaaaa atatcgatca attaagaaat aaagacaact cgttatttct
    54241 acttcaatag acccttttag aggttgtgac atttttttgt cacagcccct tttttatttg
    54301 aaaaatattt ctttctcaaa aaacaagcaa ggcgcttcaa agttcttctt gtatgcgcta
    54361 cacttagagt aaagaaaggc gggaaattaa ctatgtcaga aagaatcatt tatgcagatc
    54421 gtccatttcg tgatgaattt atcgaagaaa tccatactat agcgcctggt tatatcttta
    54481 aaacagaatt acaaccagag gatctacaaa atgtagagat cagtttgggc tggaactcag
    54541 actaccaaga aaaactatta gcctcttcta ccttgaaatg ggtccaatct atctcagctg
    54601 gtgttgatca gctacccctt gagacttttt caaagaaaca tattttactt tcaaatggta
    54661 gtggcatcca cagtgaatcg attacggagc atgtcttagg aatcatcctt gggtattctc
    54721 gtggtctttt tcaagcacaa aaggcacaga gtgacatgaa atggttaggt tcatcggtcc
    54781 attaccaatc tatccaaggg aaaaaaatac taatcattgg aactggccat attggaaaaa
    54841 tgattgcaaa aaaatgcaaa gcattagaca tgaactgcta tggaatcaat acatccggtc
    54901 atccagcaga aggaatggaa aagacttttt ctttaaatca actaaaggaa gttcttcctg
    54961 aagtagattt cgtagtcaat atcttacctc taacggagga aacaactggg ctctttgatc
    55021 agcatatgtt tgaacacttt gatccaaaat ctgtattcat caatgttggc cgtggtgctt
    55081 ctgttaagac acaagatctg gtgcaggctt taaataacca gcaactttcc tttgcagcat
    55141 tagacgtttt tgaggaagag cctcttccac aagatcatcc tctttggaaa atggacaatg
    55201 tactgattac ttcccacatt gcaggtttga cacctgattt tcaaaagaaa ttaatggcta
    55261 tttttttaac caatctgaaa agctactttg ccacccatga gcttcaaacc aatcaagtaa
    55321 aattgtctgc aggatattaa tagctgaaaa caatattttc aaaagaaaaa a
//
LOCUS       DAFELK010000013        52688 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFELK010000013
VERSION     DAFELK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.014"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            169..1227
                     /locus_tag="LP433_000987"
     CDS             169..1227
                     /locus_tag="LP433_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBL2005167.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1231..2265
                     /locus_tag="LP433_000988"
     CDS             1231..2265
                     /locus_tag="LP433_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBL2005168.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2367..3083)
                     /locus_tag="LP433_000989"
     CDS             complement(2367..3083)
                     /locus_tag="LP433_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL2005169.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3052..3837)
                     /locus_tag="LP433_000990"
     CDS             complement(3052..3837)
                     /locus_tag="LP433_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBL2005170.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3828..4577)
                     /locus_tag="LP433_000991"
     CDS             complement(3828..4577)
                     /locus_tag="LP433_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL2005171.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4875..5399
                     /locus_tag="LP433_000992"
     CDS             4875..5399
                     /locus_tag="LP433_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBL2005172.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5415..6914
                     /locus_tag="LP433_000993"
     CDS             5415..6914
                     /locus_tag="LP433_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBL2005173.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(7002..7604)
                     /locus_tag="LP433_000994"
     CDS             complement(7002..7604)
                     /locus_tag="LP433_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2005174.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7708..8664
                     /locus_tag="LP433_000995"
     CDS             7708..8664
                     /locus_tag="LP433_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBL2005175.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8969..9925)
                     /locus_tag="LP433_000996"
     CDS             complement(8969..9925)
                     /locus_tag="LP433_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2005176.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10099..10659
                     /locus_tag="LP433_000997"
     CDS             10099..10659
                     /locus_tag="LP433_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005177.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10652..11476
                     /locus_tag="LP433_000998"
     CDS             10652..11476
                     /locus_tag="LP433_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBL2005178.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11486..12103
                     /locus_tag="LP433_000999"
     CDS             11486..12103
                     /locus_tag="LP433_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL2005179.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12121..12804
                     /locus_tag="LP433_001000"
     CDS             12121..12804
                     /locus_tag="LP433_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL2005180.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13487..14770
                     /locus_tag="LP433_001001"
     CDS             13487..14770
                     /locus_tag="LP433_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2005181.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14786..15673
                     /locus_tag="LP433_001002"
     CDS             14786..15673
                     /locus_tag="LP433_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2005182.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15690..16526
                     /locus_tag="LP433_001003"
     CDS             15690..16526
                     /locus_tag="LP433_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2005183.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16529..17152
                     /locus_tag="LP433_001004"
     CDS             16529..17152
                     /locus_tag="LP433_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005184.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17149..18441
                     /locus_tag="LP433_001005"
     CDS             17149..18441
                     /locus_tag="LP433_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2005185.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18800..18897
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            19013..19594
                     /locus_tag="LP433_001006"
     CDS             19013..19594
                     /locus_tag="LP433_001006"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBL2005186.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19597..20904
                     /locus_tag="LP433_001007"
     CDS             19597..20904
                     /locus_tag="LP433_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBL2005187.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21320..21808
                     /gene="purE"
                     /locus_tag="LP433_001008"
     CDS             21320..21808
                     /gene="purE"
                     /locus_tag="LP433_001008"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBL2005188.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21801..22925
                     /gene="purK"
                     /locus_tag="LP433_001009"
     CDS             21801..22925
                     /gene="purK"
                     /locus_tag="LP433_001009"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBL2005189.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22938..24233
                     /gene="purB"
                     /locus_tag="LP433_001010"
     CDS             22938..24233
                     /gene="purB"
                     /locus_tag="LP433_001010"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBL2005190.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24413..24790)
                     /locus_tag="LP433_001011"
     CDS             complement(24413..24790)
                     /locus_tag="LP433_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005191.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            25046..25774
                     /locus_tag="LP433_001012"
     CDS             25046..25774
                     /locus_tag="LP433_001012"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBL2005192.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25774..26028
                     /gene="purS"
                     /locus_tag="LP433_001013"
     CDS             25774..26028
                     /gene="purS"
                     /locus_tag="LP433_001013"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBL2005193.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            26030..26701
                     /gene="purQ"
                     /locus_tag="LP433_001014"
     CDS             26030..26701
                     /gene="purQ"
                     /locus_tag="LP433_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBL2005194.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26702..28924
                     /gene="purL"
                     /locus_tag="LP433_001015"
     CDS             26702..28924
                     /gene="purL"
                     /locus_tag="LP433_001015"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBL2005195.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28909..30348
                     /locus_tag="LP433_001016"
     CDS             28909..30348
                     /locus_tag="LP433_001016"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBL2005196.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30371..31423
                     /locus_tag="LP433_001017"
     CDS             30371..31423
                     /locus_tag="LP433_001017"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBL2005197.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            31420..31998
                     /gene="purN"
                     /locus_tag="LP433_001018"
     CDS             31420..31998
                     /gene="purN"
                     /locus_tag="LP433_001018"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBL2005198.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            31995..33530
                     /gene="purH"
                     /locus_tag="LP433_001019"
     CDS             31995..33530
                     /gene="purH"
                     /locus_tag="LP433_001019"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBL2005199.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33546..34820
                     /gene="purD"
                     /locus_tag="LP433_001020"
     CDS             33546..34820
                     /gene="purD"
                     /locus_tag="LP433_001020"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBL2005200.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34942..35856
                     /locus_tag="LP433_001021"
     CDS             34942..35856
                     /locus_tag="LP433_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2005201.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(35989..37554)
                     /locus_tag="LP433_001022"
     CDS             complement(35989..37554)
                     /locus_tag="LP433_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL2005202.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37547..38998)
                     /locus_tag="LP433_001023"
     CDS             complement(37547..38998)
                     /locus_tag="LP433_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2005203.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(39012..40028)
                     /locus_tag="LP433_001024"
     CDS             complement(39012..40028)
                     /locus_tag="LP433_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2005204.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            40248..41336
                     /locus_tag="LP433_001025"
     CDS             40248..41336
                     /locus_tag="LP433_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBL2005205.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41390..42916
                     /locus_tag="LP433_001026"
     CDS             41390..42916
                     /locus_tag="LP433_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL2005206.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42918..44123
                     /locus_tag="LP433_001027"
     CDS             42918..44123
                     /locus_tag="LP433_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2005207.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44380..45357
                     /gene="guaC"
                     /locus_tag="LP433_001028"
     CDS             44380..45357
                     /gene="guaC"
                     /locus_tag="LP433_001028"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBL2005208.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45621..47045
                     /locus_tag="LP433_001029"
     CDS             45621..47045
                     /locus_tag="LP433_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL2005209.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            47506..48615
                     /gene="pdhA"
                     /locus_tag="LP433_001030"
     CDS             47506..48615
                     /gene="pdhA"
                     /locus_tag="LP433_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBL2005210.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48618..49595
                     /locus_tag="LP433_001031"
     CDS             48618..49595
                     /locus_tag="LP433_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBL2005211.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            49620..51263
                     /locus_tag="LP433_001032"
     CDS             49620..51263
                     /locus_tag="LP433_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBL2005212.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            51271..52677
                     /gene="lpdA"
                     /locus_tag="LP433_001033"
     CDS             51271..52677
                     /gene="lpdA"
                     /locus_tag="LP433_001033"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBL2005213.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
BASE COUNT        16855 a         9111 c        11654 g        15068 t
ORIGIN      
        1 ttttttgtgt tctagtaaaa atcactttac ataagtttca aaagtttctt taatttccta
       61 ttgttcaata agtaacaatg taaagataaa attaaaaatg ttaatacgta ttagcaaaat
      121 aaaagctttt tttattgtga ataaatgaac ataattagga ggagaaagat gaacttattt
      181 gacatttttc gatcgacttt gacagatatg tcgattgtca gtgcaatcac ttcaacagtt
      241 tttattatat tattagggtt tgtttgtaga aaaaagggga ttttttctga atctgttgga
      301 aaaattctat cgaaagtcgt cttaacagtg gctttgccag cactggcatt tcgagctttc
      361 atgcaagata tcaatacaga attactgatg caaggaatca atgtcttgat ttggggatta
      421 gttatttata ttattcttat tctagtttca aaaccttttt tcttaagcta taaaggggat
      481 aagcaaacaa cgttgcgtgt cctgacgatc tttggttcta cgaccttttt cggaacgcct
      541 atcgtcagtg cgatttatgg tcctgtcggc gtgatgtatt cctcaatttt caatattggc
      601 taccgaatct ttttgtattc ttatggatac ataaaaatga gtggcttgaa gatggaagct
      661 aaaaatatca aagcgatgtt cgtcaatcca atcattatcg ctacttttgc cggccttttc
      721 atttggctgt tccaagggta tctgccacaa gtgtcagtta caggtgcaga aggagagata
      781 agccaagtag cgtttttgcg aattgaccag actgcaccgt ggctatttca gccgatggat
      841 tatttagctg gtttaagttc accattggcg tggctagcaa tcggcgcaac attaggtgaa
      901 gtaagcttca aaaaagctgc atctgaaaaa acttcatggt attacagtct agtcaaagtg
      961 gtatttgtac ctgcattgaa tatcgtgatt ctagcagttt tgacggcaac gaatattcta
     1021 ccagtcaatt ttgaagcact ggcaacaatc gttatcatga tggctacacc agctgcaaca
     1081 gtggcagcag cctatgctat cagttttgat agggaggcac ttttagcctc caatgcatcc
     1141 ttactgtcaa ctatttttgc tgtggtactg acacctgtat ggatcgttgt attacaaatg
     1201 attcatggca taggtttatt ttcataagaa atggaggaag aaagtatgag aatcgcatgt
     1261 tacggtgttc gtccgaacga gatagatttt tttgaaaaat tgaatattta ccattatgat
     1321 ctcagtcttt atgaagaact gttgacacat gacaatatcg tgtcagcaaa ggaccatgat
     1381 gctgtattgt tgaggggaaa ttgtatagca gatgagacca atcttgcaaa aatgcaggaa
     1441 tatgggattc gttatgtttt tacacggact gtgggagtca atcatatcga tctacaagcg
     1501 gcagctgatt ttggtatgac agtagcccgt gtaccatcgt attcgccaaa tgcgatagca
     1561 gagttatctt tgacttttgc catgatgctt ttgagaaata ctgcgtatac gacgatccga
     1621 acatctttca aagattttcg agtggatgag caaatgttta gtcgtgaaat cagaaattgc
     1681 acagtaggga tcataggaac aggcaggata gggttgacgg aagctgtttt gtttaaggga
     1741 ctaggagcca aagtgatcgg ctacgatatt catcagacag aagctgctaa aaaagtattg
     1801 acgttccact cgcttgaaga gttattagcc aaaagcgata ttgtcagtat tcatgtacct
     1861 catatcccag gtgaaaacga tcaaatgatc aatgaaggat ttttagctca aatgaaaaaa
     1921 ggtagcatct tgattaatac agcccgtgga gagcttcaag ataatgaagc tattttaaga
     1981 gctttgaaaa gcaatcattt agctggtttt gcaaccgatg tttttgcaaa tgaaacagag
     2041 gtttttttcc gatccttcaa gccatgggag acgattccag accctgctat ccagcaatta
     2101 gtagaaatgt accctagagt tcttgtaacc ccgcatgtag gttcaaatac agatgaggca
     2161 ttatcaaata tgatttcgac aagtttcgag aactttcgtg aaataataga aactggaaaa
     2221 acgaaaaatg aggtatctct tcctaaagcc cgtcaattaa gataagaaaa catggatatt
     2281 cgtcaataaa atgtttaaaa atagtccaag taaacagttg ttacttctgt atacttggac
     2341 tattttgtat gggataattc gatgactcaa cagtaatctg tgagcttttt ccgcccattc
     2401 tttgtcaatt cataacaggt tagcggccgg ccgatttcca aatatttgat tctttcgttc
     2461 aatatatctt gttctactaa aaaattcaaa tatttcttga cggatatacg tgacagtgag
     2521 cttttttgag ccagttcttt tgttgaaaaa atagtatctt cttttagaat aaatgcactt
     2581 atttttttta aagtcagttt tgacagacct ttaggcaaat cgatgaatga tggtatttcg
     2641 tgaatgggag tggtgtggtt gaatacttga tcgatcaatt tctgatcggc tttttcagtc
     2701 gtttggattg tctgagagaa agcaagatac ttttcgatcg ccagctgaaa acgttgcaaa
     2761 gtgaacggtt tgatcaaata atctaaggca ccgtagcgga tcacattctt tatggtttcg
     2821 atatcatctg cagcagtgat caaaatcact gggatatcat ttccttgctg tctaagccaa
     2881 gataaaaaat ggataccact ttcgccaggc atgtatacat caagcagcag cagatctgcg
     2941 tttttttgtc tgaaatattt ttttccttct tctacatttc tgaaactttc gattacgttc
     3001 atattaggga tgctttccac aaaagtacga ttcaattctg caaccattgg atcatcttcg
     3061 attatcagga catttgtcat cattttgatc ttcctttttt ggtaattcta gatagacgat
     3121 tgtaccgcca tttgtttgtt tggaaaattc taaaaatcca ccgtggcgtt tgacgattga
     3181 atggatgaga ttcaatccaa acccacgatt gattcccttc gtcgaaaaac ctagcgtaaa
     3241 tattttttct gagatttctt ctgatatccc gacaccgtca tcgcagacgg tcacgatgaa
     3301 tacttcagct tctgtgtcat agtttaaatg aatccggacc tgtccgtttc tttcatgttt
     3361 ttgtagcacg gcttcttttg cattatcaag taagttccct aacacttgca aaagtgaatg
     3421 gatggagtca tccatctcca ttttagggat aaaagaatcg ctttctaaca gcatttcaac
     3481 agattgttct ttggcttcgt ttattttgcc taataaaaaa ccggcaattg caggtacttt
     3541 gatcagactt gagacttggc caatctcttt tttataattt tgatttagct gctggataaa
     3601 atgggtgact tcttcatact tcttcaaatc aatcaaacca gaaatgacat gaagtttatt
     3661 catgaattca tgggtttgag ctctcatgga gtttatatat tgtttcgtcc ccccaagctc
     3721 ctccattaat ttcattactt ctgatcgatt tcgtaaagtt gcgactgctc ctaaaaaacg
     3781 gtcattgcta aaaagaggtg taacgctaga aatagtttct atcccattta aatacatgga
     3841 ttgagtccga acggtcgttt gatgctcaat cgtctcttta aacaaaacgt catatagatt
     3901 atcactgatt tttttcctac ttcgaaatcc aatagctgct ctgtttggta gaaaatgttt
     3961 tttgcaggtg tattgatcaa gaggatagtt ttatcagaag agatggctaa gattccttca
     4021 tctacttcat tttcgataat cgttttttca cttaactgtt ctgctatttc ttgtggttca
     4081 agtccaagca gtactttttt cattttttgg gcaagaaaaa cggcgcctat gatgcctacg
     4141 ctaagtccaa taatcaatga aaaaacaatc attttttgtc catctttgac ttgattgtca
     4201 atcgtgttgt ttgttaagcc aacacaaact gcaccaataa tctcttgatc ataataaata
     4261 gggacgaaat agcggaagcc gaaccctaac attccttctt tttcagagaa aaattcttgt
     4321 cctccaatca cttttttcac atcttcatga cttgagaaag gaagaccgat gtaacttggg
     4381 tctgcgtgag aatatcgaat gccttcaggg tccatgacaa cgataaaatc taaattcgat
     4441 gcaatcatga tttcatttgt tattccttga atcgcatgtg tcgggtcacc agtctgcagc
     4501 tttttttgga tgagtttatc attggcaacg attttagcaa tgctagagat tttatctgac
     4561 acactagatc ggttcatcga aagaataaaa ttcctgatca atatggcaga aacaatcaaa
     4621 gaaacgaatg tggagaaaca aacgacaagg atgatcgtgt tctggagctt taatggtttt
     4681 ttcttaaaaa aaggaaacat aggctacctc gaaagaattt attgtgaaaa ttttaacatg
     4741 aaaacaaaaa tttaacaaat tgtcaacgat aaacacaacc ttcctataaa aaacaccact
     4801 gagtcggtaa aagaagctat acagaatttt caaacattgg tatgatagac gtagaaatgg
     4861 aaggaggcgt gtatatgata gggggaatcg cacttgagac gatttattgg tatacattgc
     4921 tgatttgtgc aggattggca gtcctattga ttatttttgg agatgtattc gattttgatg
     4981 gcccgcttga tccgatgctt attatccctt ggttaacttt cacaagctta tttggttttc
     5041 taggtgagcg tttaacagat caatcatctt tatttttatt tattgctagt ggaggcatat
     5101 cgatagtgtt ggtatttttg cttaatttct atatattgat gccgatgaaa catgccgaat
     5161 caacgatgtc gtcttctgaa aaaactctgg aaggacaagt agctgttgtg atcacaccga
     5221 tccctgtacg aggtatggga gaaattcagt tgaaaagtgt taccggttcc attagtcgtc
     5281 cagcttgttt ttacagcccc caagaacaga cagctgagcg gggaacgaaa gtattgatca
     5341 ttgagatcaa ggaaagaatc tgttatgtca tgccttatga aagcatgata aaagcttaaa
     5401 ggagcgtgtg ttaaatggaa ataccagttg tttttatcgc gatcgcaatc gcagctttga
     5461 ttttactgat gttgctgatc gtctttgtag cgaagtacca gacagcaaaa ccggatgaag
     5521 cgttgatcat cagtggaagt tatttaggaa gcaaaaatgt gcacattgat gaaagcaata
     5581 acaaaatcaa aattgtgcgt ggaggtggcg cattcgtctt gccagttttt caacgttcga
     5641 atcggatcag tctattatcg agtaaattgg acgtctccac ccctgaagtg tatacggaac
     5701 aaggcgtacc ggtgatgtgt gatggtactt cgatcatcaa aatcggttca tctgtagaag
     5761 agattgctac agcagcagaa cagtttttag gcaagacaag agaagaactg gaaaatgaag
     5821 caagagaagt attagaagga cacttgcgct cgattcttgg ttctatgact gtagaagaaa
     5881 tctatcaaaa tcgcgataag ttcagtcaaa gcgtacaaga agtcgcttct gtagaccttg
     5941 caaaaatggg gttgatcatc gtttctttca ctatcaaaga ggtcagagac aaaaacggtt
     6001 atcttgactc tttagggaaa ccaagaatcg cccaagtcaa aagagatgca gatatagcag
     6061 aagcggaagc tctaaaagaa acgcgtatca aaaaagctca agcagaaaaa gaatcacaag
     6121 cagctgaatt acagcgacaa acagagatcg cagaatcatt aaaagaaaaa gaactgaaat
     6181 tagcaaccta caaacaagaa caagatgttg ctaaagcaaa agcagaccaa gcctacaatt
     6241 tagaaagtgc ccgagcacaa caacaagtaa tcgaacagga aatgcagatt aaaatcgtag
     6301 aacgtcaaaa acaaatcgaa ctggaagaaa aagaaatcac acgtcgtgaa aagcaatatg
     6361 attcggaagt gaagaaaaaa gcagatgccg atcggtacgc taaagaacaa gaagcacaag
     6421 ctcaaaaagt caaagaagtg actgaagccg aagcagaacg attccgtgtg gaagcactgg
     6481 cagaagcgga agccaataag acacgtttag ctggacaagc agaagccgaa gcagcactag
     6541 caaaaggaaa agcagaagcc gaagcaaaac aaaagatcgc caatgccttc aaggaatatg
     6601 gcgaagcagc tgtcttgagt atggttatcg atatgctacc gcaattgatg cgcgaagcag
     6661 cacagccgct aggaaatatc gaaaaaatct ctgttgtcga tacaggaagc agttcaggag
     6721 aaaccagtgg agcgaaccga gtgacaaatt atgccacaaa tttgctttct tctactcaag
     6781 aaacactaaa agcgacaaca ggacttgact tgaaggaaat cgtagagaat ttgtcgacac
     6841 gtgggactac tagccaagta aatatgtatg aagcgccaaa agaggcagaa caaaactcga
     6901 tgaaggaaga ataaagtagt acacttcacc gttcaatcaa aaatggagga agacttttta
     6961 aagttcttct ctccattttt ttattttatt gcaaaagaaa attagtcctc gctatttttc
     7021 ttttgttttt ggatcttagc ttctatctct tgtaaatttg ttcttagcaa tcgttctttc
     7081 ttttggagtt cgaccaaatc ttctgatagt tcttccttct tttctgtttc aggaggacga
     7141 agaaagaaat tgataccgat tgcaatgaat gtccctataa aagtatctag tacacgttgg
     7201 atagcataca aagcggattc gccttgaggg atgctcaacg caatcagcaa caacgtagct
     7261 attgcggaaa tgataccgga attattgtta ataccatctg acacgacgat cacaataata
     7321 actagaatag gaagcaagat caattctacc aaaaaatcat tgtgaaaata gcttttgaca
     7381 aaaaaataaa tgatagctaa tgtaccacct aatgtattgc cgatgatcct agactttcca
     7441 aaagaaacgg ttgtagtcaa gtcctgacgc aaagaaaaaa cagcagataa tgcagcaatc
     7501 atcgggattc ctcgttgagt caaatgaaaa aacaagatac ataaaaaaac agctaaggca
     7561 cttttgatcg tacgcatacc tagtcgaaaa cggccaaatt gcatagagat tctccttttt
     7621 ggtcttttta ctatcatacc taaacttttg tctgatagct agtttttcat tattcaagta
     7681 taattaaaat aaaaaagggg gaagtaaatg cgtataggaa tgcgaacagt caaaacagtg
     7741 atcagtgtct tcttttcgat ggtcacagcg ggtagcttat cgctgttgta ttggccagct
     7801 gcagggatca ttgcattatt aagtgtagga aataccaagc gctctacatt gcgtacgggc
     7861 atgaatcgaa tcgcagcctt tatattagct acggcaacag cactgttcag tttttttgct
     7921 gttgggtata ctatttttgg cttcagtctt tttttattcc tgttcatccc gcttgcctct
     7981 cgcttcaaat taaccgaagg gatagtagta aattcggttt tggtcactca ttatttagtg
     8041 gaggaaaaca tgtcttggca gctgatcggc aatgaagcgg gattaatggc gattggatta
     8101 gtatttgctt tgcttgcaaa tgtttacatg ccagatcgta cgaagcagct gaaggaaaac
     8161 caaatacaga tcgaaaaaga atttcgaaat attttgagac aaatggcaga atttctttta
     8221 tcagaaaata aagaagatgt gcagatcaaa tgcgaacatt tactgacatt cattcgcgaa
     8281 agccaagaag atgccagaga acatcaagaa aactactggc tcagacagcc gctatactac
     8341 gaaacttact tctctatgag aagagcacag gccaatgtga ttaaagacat gctggaaaat
     8401 ctagagagaa tccagcaacc agcttattat ggaaaacata tctatggttt attgatttat
     8461 actgcagaaa cattttcaga gtcaaatgat ggcagacaaa ttttaacacg tattgaagaa
     8521 gtttatgtat tgtatcggca aatgcctctg ccgactagtc gccctgaatt cgaggatcga
     8581 gcagaattgt tccagttttt gcagtctttt aaaagtttta ttgaaatcaa ggcagaattc
     8641 tcccaacaaa aaatccaaaa atagaggttg tgaattcagc taatattcag gtcaaaaagc
     8701 tgatttcaca acctcttctt taaacggtgt tctcctgtca actcctcggt cacaagtcac
     8761 aatattcaac aaacatgaga agctgttttt tgaaattgct ccttgtgact cggagctgaa
     8821 cggtaggctc acaacctctt tcttaaacgg tgttcaaaag ctttcctctg cggtaataag
     8881 tccagccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat tacttgatgc
     8941 agaacagctt tttcacaacc ttttaaaatt acatattttt ccatagaact tgcatttgat
     9001 ccaagatttc gatgacatct tttgtcaaga agagagagcg attgggcaag tcaccttcaa
     9061 tcatgtgtac catattcttt atttcgtaat tcattgcttc agatgtattc ccgctttcga
     9121 tgaattcctt tgtaccatct gtaaataaga tctccgcacg atcagcacgc gggtaatcag
     9181 caatcgtcac ataaccgttc tcaaaggcaa cgataccgac ttttggcatt tttgcctgaa
     9241 aagtcaagct gacagcagca agttcatttt ctttgttacg caagatagtg acggattgtt
     9301 cgtccacgcc tgtttcaaaa ggaaccattg tagaggcaac tacttcaggt tgagagctca
     9361 aaaagaaacg agcgaaagat acagcatacg taccgatatc caacagagct cctccagcta
     9421 attctggatt gaagaaccgg tttttagggt ctggttcttt gtaactgccg aaaggtgctt
     9481 ggatcatttt taaagccccc agttttcctg tatccattat tgagcgtaac tgctgataaa
     9541 gtggcatgtt gaagattgtc atcgcttctg ctaagatcaa attcttttct tctgctaagc
     9601 gcatagcgtc agccagttct tttttattca tcgtgatggc tttttcacat agaacgtgtt
     9661 tgcctgcttc caatgctgcc aagatatggt cgatatgctg tctatttggt acagcaatgt
     9721 acacgatgtc gatttcagca tcgtctaaca tttcttgata gcttccgtaa gcttttggaa
     9781 tattgtaacg gtgagcgaag ttttccgctt tttctgaagt tctggaagca actgctgtta
     9841 gttcgctcgt ctcttgattg aagctttcgg caaactcatg tgcgatggta ccaagaccaa
     9901 cgattcccca ttgatatttt ttcatctgaa aacgctcctt catagttgga ttgagtttct
     9961 tgtctgtcta ttattataac aaaaatcacg aagaataaag aggagaggac ttgaaacatt
    10021 aaaaaaaatg aaagcagcga tttaagaggt gctttttgat caaaacttaa gtagaatagt
    10081 taaaaggagg ggataaacgt gcatcaagta tatattgatc ttattatgag tgtattatta
    10141 gaacagtttg aaactgaaaa aaatttttta gatgaatact tgctgatcag tccagaacaa
    10201 tggcaaaaat ggaaagatgg cgagaaaaat ctgccatctg aagcgatgca gaaagtaaaa
    10261 aatcttttca ctgattatga atggatgcta acgcaaaaga ttttgcgtca aacgattatt
    10321 tttcccgaaa aacgaaacgt tgccgttgca gagtacaagc aaatcaaaac acgcatcgcg
    10381 caaaaatggc ttagcagcaa agcagcaaaa gtcgagctga tccctttgaa aaataatcag
    10441 caggctggta gataccttga cttgaaagta agtattcaat atgatgaatg gggctatgat
    10501 gatattttga attttcgtct gccagcagat gttcaaaaac agatcgaagg agaaaaaatc
    10561 gaacttctcg attgggtgaa tgaaaatctg gaagaaactt acgttcatga ggcgaatggg
    10621 gaacgtgaag aacaacgaaa ggatttttca agtgaataaa tttttaggat ttggagcagt
    10681 tgtgattatg atcgcagcaa tgggctatgt tatttttagc gatgatgatt cgcatgttca
    10741 agccggcaat caagcagtcg aacgaacaag caccaaaaca actgctagta aagaaaagaa
    10801 cagtcaaaca accagcagca aggtaaagga caaagaaaca aaagatcgta cgtccaaaca
    10861 attgccagat gttaaaacag acgattggaa gctagttttg gttggtccag atcacaaatt
    10921 agaaaaagaa attgatgagt ctactcaatt ggcatcatta agtaacggat acttgatcga
    10981 caaacgcatt gctccagaat atgaagcatt tgccaaggct gctgaagcag ctggatttcc
    11041 attagtgatg gtctcagctt accggtctgt atcatcccaa caacaagttt tcgaacaaaa
    11101 tgtccaagat gtgatgagtc gtcaaggtgt atcagaagag gaggcgacaa agattactaa
    11161 agaaacgatt acggagccag gatacagcga acaccacaca ggtctggcag tcgatgtcgt
    11221 cgatcaaaac tggtacaaca gttatccttc tactgtattg gatgcaagtt acggagatca
    11281 gcctggagct aaatggatcg cagataatgc tgcgcagtat ggatttatcg ttcgttatcc
    11341 aaaaggacac gaagatataa ctaagatcac atatgaacct tggcacttac gttatgtcgg
    11401 taaagaaaac gctgagtata tcaccaaaca ccaattgacg ctagaagaat atctgaatga
    11461 attaaatgaa aagtaggaat tgatcatggc gaaaaaaaag tggaaaaagc aaaagcgcaa
    11521 gaatatccgt tggccagcag tggttgccgg tgtagcagtg atactcttag cctttgtttt
    11581 ttccttgaag aatctgtctt ctccttttac tgataatcag caagaaaatg aagcgcaatc
    11641 ccatcagcaa tttattgaac ggcttgttcc gcatgcccaa gaactacaag atggttatgg
    11701 agtgcttcct agtatcattt taggacaagc tatattagaa tcaaattggg gaaaaagtac
    11761 cttggctagc aaatacaata atcttttcgg gatcaaggct tatggggatc agaagaaagt
    11821 aagcctggaa acaaaggaat ttgttaacga agaatggata actatccaag gagacttcaa
    11881 agtgtatgat tcatgggaac agtccatgga tgaccataca caactgttcg tccaaggagt
    11941 agattggaat cctgcgctgt atgaaaaagt gattacggcc accaactatc aggaagccgc
    12001 acaagcattg caagatgcag gttatgcgac agaccccggt tatgcgcaaa aaatcatcca
    12061 ggtcatcgag acgtatcaat tgaatcagta tgaccggaga tagcaaagga gaagtggctg
    12121 atggcagaac aatttacgcc agaaatcatg acggaattga gaaaagatat cgtaagagta
    12181 ccggaaatca ttttagaagc aagcgggatc aagatatttg gaaaattgat ccgttcgatc
    12241 atctttacta cggatattgc gatcatacgt aatacaaatg cgaatgcagt aattgctgtg
    12301 tatcctttta cacctcatcc agcgattact aaaagcatta ttgaggcagc tgacattcca
    12361 gttttctccg gtgtaggtgg tggtttgaca caaggtgctc gttcttccta catgagcatg
    12421 ttcgcagaag cgcaaggttc gttaggggtc gttttgaacg gtcctacgcc tttagagaca
    12481 gtaaaagaag tttgtcgagt agttgatatt ccagttatca gtacggtaac gtcgaaatat
    12541 acagaaatag atgaaaagtt agcagctggt atttcgatta tcaatatcag tgcaggtaaa
    12601 gaaactgcag aagcagtacg ccattttcgt aaaaaatatc ctgaacttcc tatcattgcg
    12661 acaggtggtc caacggaaga aagtattgct gagaccattc aagcaggagc aaatgccatc
    12721 acatatacgc caccaagtag cggagagctt tttagtcgta aaatggaaaa atatcgggaa
    12781 actgagaaaa agaatcatga ataacaggtg agaatcaaaa gacgaggaag agcagatagt
    12841 ggctcttcct cgtcttttgt actccagtac tatttgttca gaattcaaaa aaaagagaaa
    12901 tttttttgtt tttttacctg taatgtacat aagaagagtt aaaacctttt gttattatta
    12961 gcattctaac aaaaaaatgt cttgatttat tgaagcgctt tctatagaat gaaaaacgaa
    13021 taaaaactaa aaaaggcacc cgacaattta gtagcagcta aattgtcggg gcttgaaaag
    13081 tcagcgggaa ctgaccaatc aagttgccat agtcaatgct tgtgcatcga cgtgtatatt
    13141 gtacctaatt tcatacagaa ttactagtta tttttctgtt ttttagggaa gagcgcacac
    13201 gaagaagcat gcttatttag ctatgtcaag gatattgggc agttgtctga tatccttttt
    13261 tctttgcgta attatcctcc catcattgaa gcaagaagtg tttttagcga tgaaagaaga
    13321 atcagcacta tctaattttt cttgaaagta ttgagttgtt catcctaggc agaacgataa
    13381 ggcaagtctt ggtttttatt ccccttgaaa aagatcgttt aataaatatg ttctgtataa
    13441 aaatacagta tattgaaaaa taacaatgga agtagaggtg cagagaatga agaaaagaat
    13501 gagaatcatc ttagctttaa gtgttatgtt attcttcttg acggcttgtg ggcaagaaga
    13561 tgacaaaaaa atcacgctga acatggcttg gtggggttcg caagtccgac acgatgcaac
    13621 agtaaaagta atcgagcttt atgaagaaaa aaatccccat gtgacgatcg attatgaatt
    13681 ttatgattat gaaggatatt acacaaaatt aggtacacta gcagcatcag atgatatctg
    13741 ggacattttc caactgaaca atcaatttcc tcaatacatc aatcagattg aaccattaga
    13801 tgaatatgtg gagcaaggga taattgatat ttctaatgca gatgaatcct atttagcaac
    13861 gacgacttac gacgggcaat tagttggact gtctaacggg gtgaattcgt ttgcgattgc
    13921 ttacaataaa aatatatttg aacaattaaa tatccctgaa ccagcttcaa attggacatg
    13981 ggatgaattt gaacaaatca gctatcaaat cactgaagaa ttaggaatct atgctatttc
    14041 aagattcgaa gattttatag ctggctgtat tattcaaata ccacaagttg agaaaggatt
    14101 gaatttttat aatcgggaag atctatctaa cagcttggga tttgaaaatc cagactatct
    14161 aacagatttt ttccagctgc gtaaaaatct ggtagacaaa ggggcccatc cagaaccagg
    14221 tggtggagct gcaagtacga cggatctgtc ttttcaggcg gttagggata gagaagcggc
    14281 aatggtgttt ctatcaagta accagttgac agaaatattg tcaggggctc ctgaagatat
    14341 ggagattcag ttgattaatc cacctcgcag aaaagcagat ggagaatctg gtatcccttt
    14401 acgttcttcg caaatgctga gtatggcaaa aagctcagcc cataaagaag aagctgctaa
    14461 gtttattgat ttctttcaaa acagtgaaga agccaatgaa attttaaaag gagaacgtgg
    14521 tgtaccaatc atgtcgaata ttcgagaaca gctcgctcgt gcagatgatg caactttgca
    14581 agcgacattt gattatttag aaatgatttc cgatatggac aacggcgaag tgaatgtctt
    14641 tgatagtgct ttgaatccgg aaattcaaga ccaatacaat cttttagttg aaaaagtcat
    14701 ttatgaagaa gtaacagcag aagaagcagc agagagtctt tatgagtttg cgtcaaacat
    14761 tctaggatag cagcaggagg aaggcatgaa aaaagaaaaa ctaaaacggt tcttggatca
    14821 agacaatgtg gtcggttacg tatttgcttc tccattcatc ctaggatttc tattgataac
    14881 agtgataccg atgatcttgt cactttatta ttcgttcacc gattatcgtt tgggaaatcc
    14941 agtctcatgg atcggcttgg ataattatat aaagatgctg agtgatgccc gttttttgaa
    15001 ctccatccga gtcacttttc tctatgtatt tgcatctgta cctgtgaaac tgatctttgg
    15061 tctattgatt gcttatcttt taacgaggaa tatcaaagga acgactttct ttcgttcttt
    15121 gtattatgtg cctagtttga tcggtggcag tatttctatc gctctagttt ggcgggagtt
    15181 gttttctaaa aacgggttag tgaatatttt cctggaacga ttaggcgcac ctgcgctttc
    15241 ctggtttagc gatcaaaaac tggtcatgat ccctcttgtt ttgatgtctg cttggcaatt
    15301 cggttcggca atgatcatct ttgctgcagg tatcaaagag atcccaggct cgtattatga
    15361 agcggcagag atcgatggag cgaacaaatg gcagacgttt tacaagatca cgttacctct
    15421 tctttcgccg atcattttgt ataacttggt tatgcagaca atcgcggcgt ttatgacttt
    15481 tacgcaggca tttatcatta cccaaggtgg tccgaatgat gccacgaact tttatgctct
    15541 ttatgtgtat aaccaagctt tttcttttaa ttctatgggg tatgctagtg ctatttcgtg
    15601 gatcatgctg ttgattatgg gagctgtcac ctttctgatt ttcaaatcat caaaaaaatg
    15661 ggtcgttgtg tgaatgagag gaggaagaaa tgaataatac agtaacgaaa tggtttcaat
    15721 acggttttat tttgctatta ggtctagtca tgatttatcc ggtcttatgg atgatcgcag
    15781 gttcttttaa aacggatcaa gagattatga gtggttcgct gaatttgatt ccagagactt
    15841 ttcaatggga aaattacgca aaaggatggg cggggtttgc tggaatttca ttttttactt
    15901 tctttaggaa ttcgtttgtc atctctgcag tttcgacgat agggacagtt ctgagctcga
    15961 cttgtattgc ttacgcatta tcgagaatcg atttcaaagg aaaaagattc tggttcgtcg
    16021 tcatgttagt aacgatgatg attcctgcac aagtgatttt gattccgcag tttattattt
    16081 acaatcggct gaatttggtt gggacgtatg tgccgctgat tttaccacat ttttttggac
    16141 aagcattttt catttaccag atcatgcaat tcatggtcag catccccaaa gagttagatg
    16201 aatcagcgat tattgacgga tgcagcaagt atagtgtctt taccaaaatt atttttcctt
    16261 tgctgaaacc ttcgatcatc acgacgatca tcatccagtt ttattggaaa tgggacgact
    16321 tcatgggacc attgatttat ttaaacaagc cgagatctta cacggtatcg attgccatca
    16381 aattatttgc agacgctgga tctagtacga cttacgcgag tatgtttgcg atgtctacgt
    16441 tgtcgctgct accggttttt ctgattttct tattcttcaa taaatatctt gtccagggga
    16501 tcagtacaag cggtctgaag ggctgaatat gaaaaagcca atagaagaga tgtttcttta
    16561 caagctcaac tactatgtct gtcggatttt tttaaccagt cttatcagta atgctctttt
    16621 cgctttagtt ctaggatgtt tgttcacttt aggattagtg ctgtctgctc gtgttgtcta
    16681 tctgatttat tttttgatga tgtatccttc ttattatcta tctgtccatt acttggcaga
    16741 aaaaaaggta tgttggagga aaggaaaaat caaacggatg tgtttcatca ttacgttgtt
    16801 tcagctgttt gtcattattt ttgcagttga ttggtattta ttagtgggaa agattggagc
    16861 ttggtatctg attccttttc tattgtgtct gttgcttttt gtatcccata gtttttttag
    16921 tacgctaatt gatatctgca aagaagataa agcagatagt cttgtttatt tgatcaaaag
    16981 gaatatctgg ctgttgtcaa aaaacgtcaa ggggtttctg tggtatttat gccttttgta
    17041 tggactgttc tggtgtatac agcatgattt tttactcact gcattactgt atccagggct
    17101 gccatttgtc acagtatttt gcttaaaaga aaaggagaat gactttaaat gaagaaaaaa
    17161 tatgtacaag tcggacttgg tgggagagcg cgtttttttt atgaggcaat tgcctctacg
    17221 tatcatcaaa cttgtgaact agtcggtttt tgtgatgtat ctcaaacaag gatggattat
    17281 gcaaatcgga tacttgtgaa caagtatgga cagaaaaaag taaagacatg tatgccatca
    17341 caatttgagc aactactgga tgacgtacgg ccggctgaag tcattattac gtcagtagat
    17401 cgaacgcatc atgattatat cattcgtgca atgaaaaaag gatatgatgt tatttgcgaa
    17461 aaacctctga ctatcgatga ggaaaaagct caagaaataa taacggtcca aaaacagacg
    17521 ggaagaagcc tgcgagtcac ttttaattat cgttatgcac cgtatcacac gaagataaag
    17581 gaactgatag aaagtgatgt gattggtgat gtgttttcta tccacttcga atggctgtta
    17641 aatacgcaac acggggcaga ttatttcaga agatggcatc gaaataagca caatagcggc
    17701 gggcttcttg ttcataaatc tacccatcat tttgatctag tgaatttttg gttgaacagc
    17761 cgtccccaaa aggtatttgc attcggtgga ttaaactttt atgggatgca taatgcggag
    17821 aaacgcggag tagaaatatt ttacagtcga tgctatggaa gcgaactagc taaagctgat
    17881 ccatttgcta tagacctgtc agccaatgag gaattgcgag aaatgtattt agaagcagaa
    17941 aaagacagtg gatatattcg tgaccgcagt gtattttccg atgatatctc tattgaagat
    18001 acactaggcg taacggtcaa atatgaaact ggtgcgattt tgacgtattc gctaaacgcg
    18061 tatatgccgt gggaaggatt caatgtttct ttcaatggca gcaaaggacg gatcgaaatg
    18121 aaagtgatcg aaaagtctta catcaatgca ggtggagata aaaaggatga aggagcagcc
    18181 gttcttcagt ccatccatgt ctatccgatg ttcggtgagc catatgaggt aatcgtcgaa
    18241 caagaagcgg gcggacatgg cggaggagat ccgcgtttat tagatgatct atttggtgaa
    18301 gaaaaagaag aagatccgtg gaatcgggca gcaactcacg tagatggtat tttgtcgatt
    18361 ttgacaggaa tcgcagcaaa tcattctatt gcttcaggaa aagcagtagt gattgacgag
    18421 cttgtcagct taaaagaata agaatagatt tacggaaatt acttcccgta gtttataaaa
    18481 tcttgcctta ttgccgatag gctgtctttt gaacactatt tattcggaaa aaggggctat
    18541 gacatgcttt ttgtcatgcc ttctttttat gtgggctgct tttttagata ggagaaaata
    18601 aaaataacta tttaaacccg aacaaaaagg aataatgcat taaaaatcat tagattttac
    18661 aaaaaaataa gtaaaccacg ttgtcagttt cagaaagtag tgttagactg ttttcaatat
    18721 ttgaaacaac attttttatt caaatatggc aaactgcctt cacgtgcaaa acagttgcaa
    18781 gaaaatgaat ttacactatt attagtttta catacctact tatatatcgt cataatatgg
    18841 atgacagttt ctagccagta ccgtaaatgc tggactataa gtaaaagatt ggctatttca
    18901 cccttctttt cttatgataa agtggagggt gtttttcttt aacagaaaca tagtaggttt
    18961 ttgcacaaaa gcggttattt cggtattaat aaatgataaa ggagcaaata aagtgaaaga
    19021 attagttgaa cgtattcaaa aagacggacg tatattaggc gagggcgtat taaaagtcga
    19081 cagcttcgtc actcaccaag tagaccctgt attgatggaa caaatgggaa aacggtttgc
    19141 agaagtattt aaagaacaag gaatcacgaa agttgtgacc attgaagctt ctgggatcgc
    19201 accagcttta tttgctgcaa gagaattaga tgttccaatg atcttcgcta gaaaagcaaa
    19261 aagtttgacg atggatgaag aattattgac agcttctgtt tattctttta cgaaacaagt
    19321 gacaagtacg atttctattt ctcgtaaatt tttatcttca gaagacaaag tattgattat
    19381 cgacgatttc ttggcaaacg gacaagcggc aaaaggattg atcgaattat gccagcaagc
    19441 tggagcgcaa gtagaaggaa tcgggatcgt catcgaaaag tctttccaag atggacgtca
    19501 gttacttgaa gaaatgggat tgagagtcgt ttctcttgcg cgtattgctt ccttgacgaa
    19561 tggacaagtt gagtttcttg aggaggacgc ataatcgtgg aaaaagaaac acaaaatgga
    19621 aaagctgcgg ttttagggct gcagcatctg ctagcgatgt atgcaggagc agtagcggtg
    19681 cctcttttga tcggtacagg actaggcttt aatcaagaac agatgactta tttgatttca
    19741 attgatatct ttatgtgtgg attagcgaca ttattgcaat tgacagttaa ccgatttttc
    19801 ggaattggct tgcctgtcgt tttaggatgt gcgatccaag cagtagctcc actgatcttg
    19861 atcggaacca atgaaggagt aggagctatc tacggatcta ttatcgcttc tgggatcttt
    19921 gttgtgttag tttctggtgt cttttctaaa attaaaaaac tattccctcc tatagtaaca
    19981 ggaacggtta tcaccgttat tggtttgact ttgattcctg tagcaatcga gaaaatgggt
    20041 ggaggtaatg caacagcagc tgattttggt gacaaaacaa atctgctact tgcatttgtg
    20101 acgattctcc taattgtagg cgtgcaaatg ctggcaaaag ggttcattcg ttcaatcgcg
    20161 gtattgattg gtttagtcgg aggaagcatc ttagctgctt tcatgggaat gattgatctg
    20221 agcgcgattg gagatgcgcc gttgttccat gttccacaac ccttttattt tggtaaacca
    20281 actttcgacg tatggtcgat tttactaatg atcatcattt ccatggtcag catggtagaa
    20341 tcaacaggtg tatattttgc acttggtgac attactggga aaaatgttgg agaagaagaa
    20401 ttgaaaaagg gatatcgtgc agaaggactt gccgttatct taggcggtat tttcaataca
    20461 ttcccttata ctggcttttc tcaaaatgtc ggattggttc aactttcggg aatcaaaaca
    20521 agaaaaccca tctatttctc tgcattcttc ttgattgttt taggattatt ccctaaaatc
    20581 ggtgcgttag cacaaatcat ccctgagccg gtacttggtg gaggaatgtt agtcatgttc
    20641 gggatggtgg cagtccaagg aatccgtatg ctgttggaag ttgatttcag caatgataaa
    20701 aatctattga ttgttgctgt ttctgttgga tttgggctgg gtttcaatgt tacgccgaca
    20761 ttattcagtc aaatgccgca aacattgcaa atgttcactg gaaatggcat cgtaatgagt
    20821 agcattacgg ctatcatatt gaatttgatc tttaatggat tgaaaaaaga tgaagaaata
    20881 ttggaagaag ccttcaagaa gtaatagagc aaaagaaagg ttgtgaaatc agcgttttga
    20941 cctgattgtt agagaaacaa acggaaaaat agttcctcgt attttgccgt ttgtttgagc
    21001 taataccgag ggtcagctga ttgaacaccg ttgaaggaag aggtcgtgag cctgccgttc
    21061 atctccgagt cacaaggaac aatttcaaaa aaaagcttct catgtttgtt gaatattgtt
    21121 ccttgtgacc gaggagttgg caggagaaca ccgtttatcc ataaaaagga atgtgaccta
    21181 acttttgtca cattcctttt ttttatcttt aataaacacg aacaataaaa tgtttttctt
    21241 tgttaacatt cgaaatttct ttgacatcaa aaaaagtgat tgttaaaata tgaatgtaga
    21301 aaaactggga ggaaaaacaa tgacagcaaa aatctctgtg attatgggga gtacttcaga
    21361 ttgggaaaca atgaaagaag catgtcaaat attggatgaa ttcggtgtgt cttatgaaaa
    21421 aaaggtcgtt tctgctcatc gaaccccaga tttgatgttt gaatatgcac aaaacgctcg
    21481 aaaaaaagga atcaaaatca ttattgcagg agcaggggga gccgcgcatc tgccgggtat
    21541 ggtcgcatca aaaacaactt tgccggttat cggtgtaccg gtccaatcac gaacattaaa
    21601 tggtttggat tcgcttcttt cgattgtcca aatgcctgga ggagtacctg tagctactac
    21661 agcaatcgga aaagcgggag caattaatgc tggactactt gcgatacaga tgctttccat
    21721 gtatgattta gaattggagg ctaaattggc tgaaagacgt tcaatgttgg ctaaaactgt
    21781 tatagaaagt agtgatcaac ttggttaaac ctttgttgcc tggttcaacg atcgggatcg
    21841 tcggtggcgg tcaattaggt cgtatgatgg cgattagtgc aaaagaaatg ggctttaaag
    21901 taggtgtgct ggatcctgtg agcgattgtc cagccgcaca agttgcagat tggcatattg
    21961 aaagtgtcta tgatgacacc tttgcgctga aagagcttgc cagaagaaca gatgtcatta
    22021 cctatgaatt cgaaaacgtc agtgtagagg cgttaaatgc gattttaccc atgtcattta
    22081 ttcctcaagg gacagacttg cttgcgatta cgcaagaccg cctgttagaa aaatcttttt
    22141 tggaaacgaa taacatcgtg attgctcctt atgcaacgat cgtcagtccg acggatatcc
    22201 aagatgcgat tgacgggatc ggctatcctt gtgttttgaa aaccactcga ggcggctatg
    22261 atggcaaggg gcagtatgtt ttgaaaagtc gggcggatct agctcctgcc atggaccttt
    22321 taagagaagg aacctgtgtt ttagaagcat ggatcccgtt tgaaaaagag atttcgatca
    22381 tggtggcagg aaatggtcaa ggagatttca cgacttttcc ggtcgtggaa aacatccacc
    22441 acaacaatat tcttcatgaa acgattgctc cagccgcgat tgatcaggat gtgatcgagg
    22501 aggctgagcg tattgcccgt gtgattgcag aagcagtgag cctttcaggt gttttagggg
    22561 tagaaatgtt tttaacaaaa acaggcgggc tatatgtgaa tgaattagct cctcgtcctc
    22621 acaattctgg acattattct attgaagctt gttctatgag tcagttcgat gcccatattc
    22681 gaggtatttg tggttggcca ttaggagaaa aagtacgttt gataagcaat gcagtaatgg
    22741 tcaatgtttt gggagaacaa ctgctggaaa gctatcgctt gattgagaat aagccagact
    22801 ggcaattcca tttctatgga aaaaaacaag caaaaaaagg tcgcaagatg ggacatatca
    22861 ctatcttgac agaagacatc cagcaaacgc tggaagaaat caaacaaacg aatatttggg
    22921 attagaggag aaaaaacatg ttagaacgtt atacacgccc tgaaatgggg aatatctgga
    22981 cggaagagaa caaataccgt gcgtggctcg aagtcgagat tttagcagat gaagcttggg
    23041 cagaacttgg tgaaatcccg caagaagatg tgaaaaaaat tcgtgagcat gcatcatttg
    23101 atatcgatcg gatcttggaa atcgaaaaat taacacgcca tgatgtcgtt gcgtttacac
    23161 gagcggtttc tgaaacattg ggagaagaaa gaaaatgggt ccattatggt ctaacaagta
    23221 cggatgtcgt agatactgct tatggctatc tcatcaagca agcaaatgat attttacggg
    23281 aagacttgaa acgttttacg gaaatcattg gcgaaaaagc aaaagaacac aaatatacag
    23341 tgatgatggg tcggacacac ggtgtccatg ctgaaccaac tacttttgga ttgaaacttg
    23401 ccacatggta ttcagaaatg aaacggaaca tcgaacgatt tgaacatgcg gcaaaaggag
    23461 tagaagcagg aaaaatctca ggagcagtgg gaacgttcgc aaatatcccg ccatttattg
    23521 aagagtatgt atgtaaacaa ttggggatcc gtccacaaga aatttctact caagttctcc
    23581 ctcgggatct acatgctgaa tatttctcag cgatggcgct tattgctaca agtattgaac
    23641 gttttgcaac agagatacgc ggattgcaaa aatccgaaac acgtgaagta gaagaatttt
    23701 ttgcgaaagg tcaaaaaggt tcttctgcta tgccgcacaa aaggaatccg atcggttcag
    23761 aaaatatggc tggtctagcc agagtggtgc gcggacacat ggtcactgcc tatgaaaatg
    23821 tcacattatg gcatgaaaga gatatttctc attcttcagc agaacgaatc atcttgcctg
    23881 ataccacgat tttattgaat tacatgttaa atcgttttgg caatatcgtt aaaaatctaa
    23941 cggtctttcc tgaaaacatg aagcggaata tgtctgcaac atttggtttg atttatagcc
    24001 agcgcgttat gctgaaattg atcgataagg gaatgacaag agaagaagct tatgatcttg
    24061 ttcagccaaa aactgcgtac gcttgggaca accaagtgca gttccgcccg ctgttagaag
    24121 aagatccaac catcacatcg gtattatcta aagaagaaat agacgatgcc tttgattatc
    24181 atcatcattt gaaaaacgtt gacgtgatat tcaaacgagt aggtttggaa taaagaagag
    24241 tgagttgcaa aattcaatta aaatagaata gcaaaaataa ccaaaaaaga agcagatccg
    24301 ttagcggttc tgcttctttt agtttattat attttcttat caataatagg aacctgattt
    24361 taaaagcggc tacctcttta ccgtgcctct ttacatacaa aaaatagagg aattaagcgt
    24421 aaatggcttg gctattataa ctaaaatgct ggttatggag atgttgcagc aagttttcga
    24481 gaaaagcgta ttccatctct tgtccattga ataagatctg gatacgataa tgatttttga
    24541 aacgcttctg ttcatgaatc tgactgattg aaagttcgcc tttgtgttct gtctgataaa
    24601 gaaaagtcct tttacggcat tcagcacagc gcttggttgc tcggcggatt tttcggaatg
    24661 tataaaaact agtatcttta ttgcataaat aaacgtcttt gatcgacagc aaatcattat
    24721 atagacagga acgttcttca gctgttaatt ctgataaaaa aagctgacct tgttttattg
    24781 catcttccat cggcaagtgc ctcctcgaac ccattaacca aatttttagt taattctaat
    24841 ataccatcat taagtataaa tgtaaacgct tgttgatggt ataagatttt cgtttctgat
    24901 aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac atatttttgt tgatttataa
    24961 aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa aaacgatgta tttgctttta
    25021 atgtaaataa aaaggagaga cgtacatgga gaagaaagaa cttttgtatg aaggaaaagc
    25081 caaaaaaata tatcttactt ctgatgagaa cttgatttgg atagaatatt tagatcaagc
    25141 aactgcgttg aatggcgcga ggaaagacca gataagtgga aaaggagaat tgaataatca
    25201 aatcacaagt gcaattttcc gttatctgac tcaaagagga ataaaaaatc attttattga
    25261 acaattgtct aaaaccgaac aattagcaaa aaaagtacaa attatccctc tggaagtggt
    25321 tatccgaaat attgcagcag gaagtttctc aaaacgtcta ggtgttcccg aaggtaaaga
    25381 attcatcaaa ccaatcattg aattctacta taaggatgac cagttggatg atccatttat
    25441 caatgaagag catatctatt tcttacaact tgcaaagccg gaagaaatca gtgagctgaa
    25501 agcccaagcg ttggctatta atgaaatttt gaccgaatta tttgctaagg tcggtttggt
    25561 tttagtagat ttcaagctag aatttggccg gtcgaatgga caaattttgc ttgcggatga
    25621 agtaacaccg gatacttgcc gattatggga tgaacgtacg aatgaacata tggacaaaga
    25681 cgtttaccgc agagatctag gtgatttgat cccagtctat caagaagtat ataaccgtct
    25741 atcggaacta actgaagaaa aggagcgagt atgatgtatt tcgtaaaagt atatgtaacc
    25801 tataaagatt cagtgttaga tcctcaaggg gaggcagtaa aaaaagcagt ccatcgtatg
    25861 ggatatgaaa caatcgaaga tatccgaata ggaaaatact ttgagataca acttgctgat
    25921 gcagaagaac caatcgatac agtgattgaa acgatttgtg acaagctgct tgcaaatgta
    25981 aatatggaaa cataccgata tgaaatcaaa aaaatggagg aagtataaca tgaaatttgc
    26041 ggtcatcgtt tttccaggtt caaattgtga cgcagatatg ttatgggcag ttcgcgagat
    26101 catgggcgct gatgccgaat ttgtacggca tgatgagtcc tctttagaag gatttgatgg
    26161 ggttttactg ccgggaggat tctcctatgg tgactatttg agatgcggtg cgattgctcg
    26221 gttttctaca atcatggaag aagtgattcg ttttgctgaa gaagggaaac cagtattcgg
    26281 tacatgcaat ggattccaga tattgacaga agcaggactt ttgccaggtg tactgagacg
    26341 aaatgagtct ttgcatttta tttgcaaaac tgtaccattg aaagtcaacc ccaagacggc
    26401 ctttacttca gagtatgaag ccgacgaaat aatctatctt ccagttgctc atggggaagg
    26461 aaattatttc tgtgacgaag aaacacttca agaactaaaa aaaaataatc agattgcctt
    26521 tacttataat gacaacatca acggcagcgt ggaaaacatt gcagggatta cgaacaaagc
    26581 agggaatgtg ttaggaatga tgcctcatcc agaacgtgca gtagaagact tgctaggatc
    26641 agaagatggg aaacggttct ttgcttccat tttaaaaaac ttcggaaagg tgaccgtata
    26701 gatgaaaaca ttgaaagaac cgacagctga agagatcaag aaaaaaagaa tctatgccga
    26761 atggggattg actgatgaag aatatcgaat gatcgaagaa gatatcttag gaagaatgcc
    26821 taattatacg gaaactggac tgttttctgt tatgtggagc gaacattgtt cctataaaaa
    26881 ttctaaaccg gttctacgca aatttcctac tagtggacct catgtgttgc aaggccctgg
    26941 agaaggcgca ggcatcgtcg acatcggtga tggactagca gttgtcttca aagcagaaag
    27001 tcacaatcat ccttcagccg tggagcctta tgaaggagct gcgacaggag ttggcggaat
    27061 catcagagat attttcagca tgggggctcg tccaattgcg ttgctagatt cattgaggtt
    27121 cggcgaatta gataatccaa gaacgaaata tttactagaa gaagtagttg caggtatcgg
    27181 cggatacggc aattgtatcg gcataccgac tgtaggcggc gaaattgcat ttgatccttg
    27241 ttatgaagga aacccattag tcaatgcaat gtgcgtaggt ttgattgaac acaaacatat
    27301 ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg tatgtaggtg caaaaacagg
    27361 tcgcgacggt atccacggag caacttttgc ctcagaagaa tttaatcaag aagaagaaca
    27421 gcaacgttct gctgtacaag taggcgatcc ttttatggaa aagctgctgc ttgaagcgtg
    27481 tttggaatta atcttgcatc attcggattc tctaataggt atacaggata tgggagcagc
    27541 aggacttgtt tcatctagtg cggaaatggc ttcaaaagct ggctcaggac ttatattgac
    27601 attagatgaa gtcccacaaa gagaaactgg gatgacacct tatgaaatga tgttatcgga
    27661 atcacaagaa cggatgttga tttgtgttaa atcaggagag gaagaaaaaa tccaagaact
    27721 atttcagaag tatgatctag atgcagtcac tatcggtaaa gtaacagacg acgggcaata
    27781 tcggctatat catcaaggag aagaagtagc aaatctgcca gtcgatgcat tagctgaaga
    27841 tgcaccagtt tatcataaag aaatgaaaga accagctcga atcgtagaat ttcagcagtt
    27901 agctccttat cagccagtta tcgaagaacc tggacaagta ttgcttgatc tgctgcagca
    27961 accgacgatt gcttcaaaac gttcaatcta cgaaacttat gattcacaag tacaaaccaa
    28021 tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg gttagaggga cgaataaagc
    28081 gttagctatg accacagact gcaacgcgcg ctatctgtat ttggatccaa aaatcggagg
    28141 acaaatagca gtggcagaag ctgctagaaa tattattgct agcggtggta agcccttggc
    28201 gatcaccgac tgcctgaact atggttctcc tgataaacca gaagtttttt gggaattatc
    28261 gacttcagct gacggaattg ctgctgcgtg tgaaacgtta ggaactcctg ttatttcagg
    28321 aaatgtctct ttatataatg aaacggatgg tcaagcaatc tatccaacac caatgattgg
    28381 tatggtcgga ttgattgagg atcataaaca tatcactact caggaattca aaaaatcagg
    28441 ggatctaatc tatatattag gtaagacgtt tgcagatttt gatggcagtg aattacaaaa
    28501 gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt gatctatcca ttgaaaagag
    28561 aaaccaagag ttagtattga cagccatcca aaacggattg attgaaagtg ctcatgactg
    28621 ttcagaaggt ggcttggcaa ttgcactggc agaatcagct ttcaaacatc agctagggat
    28681 atctgtacag tttgaattgt cctctgctca attatttgca gaaactcaat caagatttgt
    28741 gttgacagtc gcaccggaaa ataagacacg attcgaagaa atgatgggag atgctgctgt
    28801 tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt tcagcaactg acggtcagat
    28861 caaaatagaa actgcagtag caagaaagtg ctgggaggat gcaatcgtat gtcttatgaa
    28921 gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt ggggtcatcc agacgccgct
    28981 agtgtggcat acttcgggct ccatagtctt cagcatcgag gacaagaagg tgcaggtatc
    29041 gtgtccaatg atcgaggaaa gcttaagggg catcgagatt tggggctgct ttctgaggta
    29101 ttcaaagatc aaagaaaatt gcagcagtta acaggagaag ctgcaatcgg acatgtacgt
    29161 tatgcaacag caggcaatgg aagtgtggac aatattcagc cttttctatt caaatttcat
    29221 gatcagtcga tcggcttagc gcataatggt aacttgatca atgctcgttc ccttagaaaa
    29281 gagttagagg aaaatggggc gatcttccat tctaactccg atacggagat attgatgcat
    29341 ttgatccgac gaagtgaaga aacagatttt ttaaataaat taaaaagtgc tttgaatgaa
    29401 gtcaaaggtg gctttgccta tttattaatg acagaaacgg caatgattgc cgctttggac
    29461 ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa acggagcata cgtgattgcc
    29521 tcggaaactt gtgcattaga agttattggg gcacgtttta taagagatgt ccagcctggt
    29581 gagatagtga tcatcaatga cgaaggaatc cagattgatt gctttacgaa ggacacgcag
    29641 ctttctattt gttcgatgga atatatctat tttgccagac cagattcaaa catcgcaggg
    29701 atcaatgtgc atactgcacg gaaaaatatg ggacggaatt tagcgaaaga atcgccagta
    29761 aaagcagata tggtcgttgg cgtacctaat tcttctttgt cagccgcaag cggttatgcg
    29821 gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa atcaatacat tgcccgaaca
    29881 tttatccagc caacgcctga gctaagagag caaggtgttc gaatgaaatt atctgctgta
    29941 cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg attcaattgt tcggggtacg
    30001 acaagcagac ggatcgtcca tcttttgaaa gaagcagggg caaaagaagt ccatgtgagg
    30061 attgcttctc ctcctttgaa atatccatgt ttttacggga ttgatattca aacgcgtaaa
    30121 gaactcattg cggcaaatca cacgattgat gaaatcaaag aatgtatcgg tgcagattct
    30181 ttaggttttt taagtgaaga gggtctgatc gaatcgatcg gtctggaaaa agatgctccg
    30241 tattcaggat tgtgtatggc ttatttcaac ggagattatc cgacgccgtt atatgactat
    30301 gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt tcttttaaaa gcagaccaag
    30361 aagggagtat atgaattcaa tggcaaatgc atacgcaaaa gctggcgtag atgtcgaagc
    30421 tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa aaaacggaac gtttaggtat
    30481 gatgggcgct ataggaggat tcggcggttg ttttgattta tcggtctttc aattaaaaga
    30541 gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa ttagcagtgg caatcgaagc
    30601 agacaaacac gatacaatcg ggatcgactg cgtagcgatg tgtgtcaatg atatcttagc
    30661 acaaggcgca gagccgttat atttcttaga ctacttagca acggggaaaa atgatccgtt
    30721 acgtttggaa aatgtagtaa aaggtgtagc agatggatgt gttcaaggaa atatggcgct
    30781 gattggcgga gaaacagctg aaatgcctgg tatgtactca ggtaatgatt atgatctagc
    30841 cggatttgct gtagggatag ctgaaaaatc tcaattattg acaggagaaa cgatcaaccc
    30901 aggagatgtg ttgcttggaa tagcatctag cgggattcat tcaaatgggt actctcttgt
    30961 tcgcaaaatt ttctttgagc agcagcagtt ttctttatca tcaaaactgc cagaattgaa
    31021 aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc tatgtttctt ccttgcttcc
    31081 gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc actggtggag ggtttgtaga
    31141 aaatatcccg cgaatgttac cagaatctat ggctgcacaa atcaaacttg gctcatggcc
    31201 gattcttcca atattcggct gtttacaaaa atatggtgaa attcctgaga tggagatgta
    31261 tgaaatcttc aatatgggca tcggtatggt cctggcagtc gaagaatcga aagtaaaaga
    31321 aatagtacac gaaattgagc aagctggcga aaaagtttat gaaatcggga aagtgatcgc
    31381 caaagaaaaa catcgtgtgg tgtttatagg agaagaacga tgagaatcgc tgtttttgct
    31441 tctggaaacg gaagcaactt tcaagcgcta gccgattatc tatcgaaaaa aggattggaa
    31501 tcttcgattg actggttgtt ttgtgatcag cctgaagcat atgttttgaa acgtgcaact
    31561 gcgttgagtg taccggcaga ttgtttttca cctaaagaat ttgattcaaa aaaagagtat
    31621 gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg atttgatcgt attagctgga
    31681 tatatgcgaa tcattggacc ggtattgctg aaaaattatg ataaaagaat catcaatatc
    31741 catccgtctc ttttacctgc cttccctggt ttgcatggca tacgtgatgc ctttgaagct
    31801 ggagtaaaag aaacgggtgt cacaattcat tatatcgacc aaggtgtaga tactggacca
    31861 atcatccggc aggaaaaagt gagaattgaa caggaggaca cgttcgattc tttagaagaa
    31921 aaaatccata gagtagagca tcgaatctat ccagaagtga ttagtgaaat tattgaaaat
    31981 ggaggctatc tgaaatgaca agagcattga tcagtgtatc agataaaact gggattgtag
    32041 cattcgccca aggtttgatt gaacaaggag tagaaatcat ttcaacagga ggaacaaagc
    32101 atgcgttgga taaagctggg atcaaaacgc tttcgatcga agaagtgaca gggtttcctg
    32161 aaatgatgga tggccgtgtc aaaacacttc atcctaaaat ccatggtggt cttttaggaa
    32221 gacgcgatct ccctagccat atggaggcaa tggaaacgga aaatatccaa ccaatcgact
    32281 ttgtttgtgt caatttatat cctttcaaag aaacgattat gaaaccagat gtcgaaatag
    32341 cagaagctat tgaaaacatt gatatcggtg gtcctagtat gctccgtagt gcagcaaaaa
    32401 accatgaatt tgtcacctct gttgttgatc catctgacta tgaagaagta ctttcagaat
    32461 tacgtcagta tgggcatact tcactttctt tcagacaaaa actagcggca aaagtctttc
    32521 gtcatactgc ggcatatgat gcactgatcg ctcaatactt aacggattgg gtggaagaaa
    32581 aagaaccgga aaaattgaca cttacgtatg aacgaaaaca aacgcttcgt tacggtgaaa
    32641 atagccatca agccgctgcc ttttatcagt ccgctcttct ggaaaaatat tcgatcgcag
    32701 cagcaaaaca actccatggg aaagaacttt cttataataa tatccgagat gcagatgctg
    32761 cgctacggat catgaaggaa tatgacgagc caacggtagt cgccttgaaa cacatgaatc
    32821 cttgtggtat tgggacagca tctacgattt tagaagcgtg ggaagcagcg tatgaagcag
    32881 atcctgtttc aatctttggt gggatcatcg ttttgaatcg agaagtagat ctgccaacag
    32941 cagaacagat gcataagctg tttctagaaa tcatcattgc cccttcttat acacaagaag
    33001 ctttggaatt actgcaaaaa aagaaaaaca tccgattact gacagtagac tttgcgcagg
    33061 aagaaaatca aaatcgagaa gaaacggtct cagtcttagg tggacttctt gtacaagatc
    33121 aagatctggc aatagaaaat gaagaagagt ggaaagtcgt gacaaaacgt aagccgactc
    33181 cagcagaagc aaaagcatta gtgtttgctt ggagagctgt caaacatgtg aaatctaatg
    33241 cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg agccgggcag atgaatcgag
    33301 tcggttcagt aaaaattgcg attgaacaag cgcaagagaa aatggaaggt gcagttttag
    33361 ctagcgatgc ttattttcca atggatgatt cggttgaata tgcagccaaa catggtataa
    33421 aagcaatcat tcagccagga ggaagcatca aagaccaaga ttctattgat atggcgaata
    33481 aatacgatct agcaatggtc tttactgatg ttcggcattt tagacattag agaggagtcg
    33541 gataaatgaa cattttggtg atcggtgcag gtggtcgtga acatgcaata agtaaaaaac
    33601 ttttagccag tccgaaggtg gatacggtgt attgtgcgcc aggaaatccg gggatgacaa
    33661 aagatggtat caattgtgtc gctatcagtg agcgagatca ttcagcgtta atccattttg
    33721 ttaagaaaga ggctattgat tggagtatcg ttggtcctga agttcctttg ttaaatggga
    33781 tcgtcgatga ttttatggcg gaaggattga aaatcttcgg tccgacaaaa gcagcagctc
    33841 tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga tacttatcaa atcccgacag
    33901 ctaaatccag aagttttgaa tgttacgaaa aagcagcagc gtatatcaaa gaaaatggtg
    33961 cgccaatcgt agtgaaagcg gacggcttag cagctgggaa aggtgtagtc gtggctacca
    34021 cagtgaagga agcgctggat gcggcagaac aaatgttgaa ccagcatcga tttggggata
    34081 gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga agaattctcc cttttggcgt
    34141 ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca agatcataag cgggcatttg
    34201 ataacgataa agggccaaat acaggcggaa tgggtgctta ttcaccagta ccgcaaattt
    34261 caaaaaagat gattgaaaaa gctgtggaag aagttttaaa accagcggct ttgggaatga
    34321 aagaactagg acgctctttc acgggtgttt tatatgcggg tttgattgct acgaaggaag
    34381 gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc tgaaacgcaa gtcgttcttt
    34441 ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt attagagaat cgtacagtag
    34501 agttaaagtg gcagcaagaa ggatacaatg taggcgttgt ggttgcagct gccggttacc
    34561 ccgaagaata tgagacagga atggttctac cagattttct ggaagaagag ctttctgttt
    34621 actatgctgg agtttcctca aataacggca aactagttgg agcaggagga cgtctttatt
    34681 tagtagaagc atacggtgag acgatcaaag aagcacagaa aaaaatttac accgcgttaa
    34741 tggataaaac gacagatgga acattttatc gtacagatat tggagaaaaa gctgccaata
    34801 gcgaactgat cgtgaagtaa atcagctgct tccatttata aaaaatacaa caaacataat
    34861 cggaagcgcc gattttagtg aagccttttc ataaagagtg tggtacactt ttgttgtgta
    34921 tataaataag gaggagttca gatgaaaaaa attcaattag gtacttctga tcagaaagca
    34981 gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg aagatccagt aaaagtgatt
    35041 gagacagctt atgaaaacgg cattgatttt tttgaccatg cagatattta tggaaacggt
    35101 gaatgtgaag aaatctttgc agatgctcta gcaaaaacat caatcaaacg agaagatctt
    35161 tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt ttgatttttc taaaaaacat
    35221 atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa tggattatgt ggatgcttta
    35281 cttcttcatc gtccagatac attggtagaa ccagaggaag tagctgaagc gtttgatgaa
    35341 ttggaacggt caggaaaagt tcgttatttt ggcgtcagca atcaaaaacc aatgcaaatc
    35401 gaattgctga aaaaatatgt tcgtcaacca ttagtagcta atcagctgca atttggcttg
    35461 aaacatactg gaatgatcga tcaagggatt catgtcaata tgacagatga agcaagtatc
    35521 gatcatgacg gtagtgtact tgattattcc cgattgcatg atatgacgat ccaagcatgg
    35581 tcaccatacc agtatggatt ttttgaaggt gtatttatcg ggaacgaaaa attccctgaa
    35641 ttaaaccaaa cattagaaga actagcagct aaatatcaaa cgacaccaac tggcttggct
    35701 tctgcttgga ttttacgcca tccagccaat atgcaagtga tcgccggtac gatgaacgta
    35761 gggcgaatca aggaaatcgc tcaagcttca gaaattaata tgtctcggga agattggtac
    35821 gaattgtacc gtgctgctgg aaacatttta ccttaaagat tgtcataagc aggtcaaaag
    35881 ggctataaat taaaaagaca gaataacttg aaagctgttt tcagcttcga gatattctgt
    35941 ctttttttat tgcaaatgga aagagtatca ttgtacggat ttcgtttatt agttattttt
    36001 gtttttaagg aaaagctgtg tccgatattc ttttggagaa atcccttgtt ttttcttaaa
    36061 taaataactg aaatagttag ggtcattata accaatttca aaagcaatat ctgaaatacg
    36121 atagtctgat tgctgcaata atttttttgc taattcgatt ctttgttctg tcagataatc
    36181 gatgaatgtt tggttaaacg attgagaaaa aatcgtactg aaatgagagg gacttaatgc
    36241 aacttgttga gcgacccaag ttaaggacat atctggatcg gtaaaatttt ctttgataaa
    36301 atccaatgca tggttcaaaa ttggctgata tttgttcctt gaaggctgtg agggcagagc
    36361 agttaagaaa gaaatgaaca tataaactgt cgaacggtaa agcgagtcgt cggcgctgat
    36421 tgctaagcgt tgactggtgg atgtgcaatg aaccatttct tgcgggattt tcttttcttt
    36481 caggcagaca tgctggagta gcttagtcaa gacaaataaa cgatataatc gtgttcgagt
    36541 tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta gatacttcgt ttttcgataa
    36601 tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa tcaactggaa gtttcgcttc
    36661 ttgaatcaaa tcctcatagc tgataatttg ttctttaagg gaactggcgg tttcaagtat
    36721 catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt ctttctgcga caggaccaat
    36781 ggcgacagaa aaattatttt tttgtccctt ttctaattca tggaccaacg tttgggctac
    36841 ctgataactg gtctcgatca cattttcttc aagagaatca actattaaaa atttgatgaa
    36901 tcgagaggaa acagcagaga agatcacttg ttgattctcc ctaaataaaa acttcaaata
    36961 atcactgaga tgagcgtaat cttcaaagtc tgtactgact tggtttgctg ctaataatac
    37021 ggtcattttt ttccctgcta aagagcgatt gaaagattca gcaagtttca atgtttcact
    37081 gatcgtaagt gagcctttga acaaaccgtt caagaaatga ttttttttca attcgaaaac
    37141 aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct aaagcagtta ctgctttttc
    37201 tattgcttgt ttcaattcgc tacttttaat cggtttaagc agataatcat ctgcctgtac
    37261 ctggattgct cctttcatat aatcgaaatc gtcgaatcca ctaataaata tgagacgagt
    37321 ccaaggaagt agtttccttg cttcttttga aaaagtcaac ccgtccatga aaggcatttg
    37381 gatatcagtc agaatgatgt cgggctgtaa gtcgataatt gaagacagtg ccatctcacc
    37441 atctccagct tcgccgacat aagtgattgg ataataagaa ccaaggacag ttatttgttc
    37501 ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata aaaactttat acatgtttgt
    37561 ttcctccaat tgttttggga gatagaggga tcatcagtgt gacagttgtt ccttctcggt
    37621 atttgctgtc aatcgtgata ggtttttgat catttccgta ataaagaagg agacgcttgt
    37681 ttacgttgta aagtccgtag ccgatactga aatctgaatc gatccctttg gctaactctt
    37741 tacgtatttc tgccagtttt tctgcaggga tgccaatccc gttgtctata actttgaatt
    37801 ggatcatctc atcaattttg catgtggtaa tacgaataaa tcctttgtga cggacgtact
    37861 tcgttccatg gtatacagca ttttcaatca atggctgcaa gatcattttt aaaatagaaa
    37921 caggaaaaag tgtttctggt atatcgatct tatagtcaag catatggccg tatcttattt
    37981 ttaagatgac tagataatca ttgatatggc taatttcttt ttcaagagga atccagtctt
    38041 gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc atgggtcata gtcagagctt
    38101 cttcaaagca gtcttgttcg atcaaagaaa taatggcatc caaactgtta taaataaaat
    38161 ggggagtaat ctgagcttgc aatacacgaa cttcactttg tgctaaatgg tattgtttca
    38221 aagcgttctc ccgtaaagac tggtttagat cttccgccat tttattcatg ctagcggtaa
    38281 gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa gccaaggttc cctgaagaaa
    38341 gttgttctga catctcgatc agctgattga tcggttcttg gacctttctc tctaaaaagc
    38401 gacgattctt tttcgcatag aaaaaaatgg tactaagaac tccaagttcc actattgtta
    38461 atagaatgag cgagcggaca agtgtcgtat tttttttgct tgctaagtcg atctccacac
    38521 gaacaaaatc ttgtaagata tctgacagca gttgagtgac agaatctacc tgattgatga
    38581 tctcttcatt ggtatccata aaatcttttg ccaagatatt attgatcagc tcgttttgat
    38641 aatcttccag tgtatcgatc gtacgtagcg atacatctaa cgtactaatt tctttaagtg
    38701 tatttgtatt atttttgctc tctcgaatat cattcctaag ttcttctagg atattttcct
    38761 cattgaactc atctacggtt acttggccag aaatcaagtc ccacatactt tccaaaactt
    38821 tttgatcaac cttcaaagca attgcatctg ctttttggat atttgcgatc gtctgttgat
    38881 aaatcaaaag ctgttgcgaa tataacagta tgctcagtag caaagggata acagcaaata
    38941 gaagcatggc tttgtttgct tgggcaaaaa tctgttttat gcttaaattt tttgtcatga
    39001 tacttctcca gtcaataatt tctggttggg atgttagcta tattctgctg ggaaaagaca
    39061 gtctcggaaa taaaaatatc tttaggtaat gtttttcctg tttgaatatt tccaaaataa
    39121 cgagtaacgg tattggctac ataccagccg acatcaggtt tacactcgac tacacaattg
    39181 acgattcctg agcgtagctt ctcgatcata tcttcttgtc catcaatagt tacaatgatc
    39241 aaatcttctc caggtttgat tgatgtttct tttatcgcag ctaaagcacc gtgagtcatt
    39301 tcatcactat ggctgtataa tacatcgatt tcggataaat catttgtttc taaatatcgt
    39361 ttcatctggt cttttccttt catccgaata aaatcaccga caattcggtg aacaatagtc
    39421 atcggaggtt tatggtcgat ggttccatct ttttttaggg ttggtttacg attgattgat
    39481 tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt tctctgaacc agcaagttct
    39541 aggattctga tttcctgttt ctttgaattt gtgaagtgat tgctgacaaa taaacccgcc
    39601 cgatttcctt ctgctttgaa actggggcca atgtgggtga cgaaaagctc gggatcattc
    39661 gtttgaatat gtctgtcgac aagtatgaca gggatccctg ctcgctttgc ttcttttaat
    39721 acagagtccc acccggattc ttgcaaagga gtaaaaatga tcatatccac tttataggca
    39781 atgaacgtcc gtatatcttg gatttgccgt tcctgattca tgtagccatt tcggtagaga
    39841 acttggtaat cttctttttc aagcgcagtg ataattgatt cagtatgctt tttccgccag
    39901 ctactctccg ttcctgattg cgaaaaacca acgactagtg ggtcaggtgc ttcctttgta
    39961 ttaggtgtac accccatcat ttggtaagcg attacaacaa gggctaaaaa aaataaaaca
    40021 cgtttcactt taaatcactc catctggatt tgttagtact atcttatcag ataaaaggga
    40081 aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga aacttaaaaa aatccaagac
    40141 aaaaaaagta cacctaaaaa atttaaagta aatcccataa aaaaatcaat gttaacgctt
    40201 tctttattag ctatactcgg tgtatcaatt gaaatggggg ataaaaaatg aaaaacaaat
    40261 ttagaaagat tgttgggact atcgctattt tgaccgcaag cattctatta agtgcgtgtg
    40321 gcaattcagg atctgcagat gatagtacgg ggtatgtagg aatcgctatg ccgaccaaat
    40381 cagcagaaag atggatcgct gatgggaaca acatggtctc ggaattagaa aaactgggtt
    40441 ataaaacaga tcttcaatat ggagaagata aagtagaaaa tcaagtagca caaatagaaa
    40501 atatgattac aaaaggggta gatacacttg tgattgcttc tatcgatggt tcggctttaa
    40561 ctgatgtgtt agctaaagca aaagaagcag atatcaaggt gatcgcctat gatcgtttac
    40621 tgatgaattc agaaaatgtc gattattacg cgacttttga taattttgga gtaggtgtat
    40681 cgcaagcagc ttatattgaa gagcacttag gattgaaaga aggaaaagga ccattcacga
    40741 ttgaattatt tggtggctcg cctgacgaca acaacgcact aatcaattac aacggagtga
    40801 tgtctgtttt acaaccatat atggacaacg gtcagttggt cgtgccatct ggacagacga
    40861 gtttcagtca aatcgctacg cttcgctggg atggttctac ggcgcaagca aggatggata
    40921 atctgttaag cgcaaattat actgaccaaa cattggatgc tgttttgtcg ccatatgatc
    40981 caataagttt aggaatcatt tcgtcattaa aaggcgtggg gtatgggagt gaaagtaaac
    41041 ctttacctgt gattactgga caagatgcga cagttgctgg cgttaaatcg atcattgccg
    41101 gggaacaaac acaaacgatc tttaaagaca cacgtatctt agcaaaaaat acgattgaaa
    41161 tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa tgatactgaa acttatgata
    41221 atggggtgaa aactgtccct acgtatttag caaatacagt atctgtcgat aaagataatt
    41281 atcaagcaga gctgatcgac accgattatt ataaagaatc cgatctgaaa aattaagagg
    41341 aaccaaacaa ggaactaaag agatctaagt cagagagagg ataagaatta tggcggattg
    41401 tattttaaaa atggcagata tcaccaaaaa attttctgga atccgagcgt tagattgcgt
    41461 gaatctgatg attgaacgtg gggaaatcca tgcattgtgc ggagaaaacg gagcgggaaa
    41521 atcaacattg atgaatgtct tgagcggctt gtatccatat ggctcctatg acggggaaat
    41581 cttttatgat ggaaagctgt gtcaatttaa agatttgaaa gatagtgaag aaaaaggcat
    41641 cgtcatcatt catcaagaat tagcactaag tccttatctt tcaataaaag agaatatttt
    41701 tctcggaaat gaacaagcag aaagaggcgt gattgattgg gaactgacag aaaagaaaac
    41761 atatgaactg ctgaataaag tcggtttgtc tatcgacccg aatcttctag tatcccagat
    41821 tggcgtaggg caacagcaac tagttgaaat agctaaagca ttatcaaaat ccgtccgtct
    41881 gttgattttg gatgagccta ccgctgcatt gaatgaagaa gaaagcgcga atttgctgag
    41941 attgatccga gagttgaaag agcaaggtgt aacctccatc attatttcac ataagctgaa
    42001 tgaaatcgtg gatatcgcag atcgaatcac cattttacgg gatggacaga cgattgagac
    42061 actagaaaat gaaatgatca gcgaagagca tattattcgc ggaatggtgg gcagagattt
    42121 agttgatcgt tatcctgaaa gaaaaccgga tattggagaa gtttatttta aagtagaaga
    42181 ctggacggtc tatcaccctc ttgatcacga gcgaatcata aacgaccaca tcaacttgca
    42241 tttgaaaaaa ggagagattg taggaatagc tggactgatg ggagcgggca gaactgaatt
    42301 cgctatgagt ctatttggac attcttatgg aagcaagata tccggacgta tattaaagga
    42361 aggggcagag atatcagtta agaccgttcc ttcagccatt gcaaacggac tcgcttatgt
    42421 ctcggaggac cgaaaatctt taggactgaa tctgctgatg gatattcggg aaaacgtgac
    42481 gctgagcagt ttggataaaa taagtcaaaa aggagtatta gataaagaaa aagaagtaac
    42541 tgaggcagaa aatttccgga aaaagatgcg tataaaaaca aactccatcc atcaaattgt
    42601 cagtagtctt agtggtggga atcaacaaaa agtcgtttta tccaagtggc tgatgacaca
    42661 acccgatatt ctttttttgg atgagccaac ccgtgggata gatgttgggg caaaatatga
    42721 gatctacacg attatcgaag aaatggcagc aaatggcaaa gctgtctgtc ttatctcttc
    42781 tgaacttcct gaaatattag ggatgtgtga tcgaatctat acgatgaacg aaggacgtat
    42841 tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc ttgatgaaat taatgacgaa
    42901 agaagaggtg ggttaagttg gaacaggcaa aaaatcttac ggataaaaaa gagaaaaaac
    42961 taaatttgaa aagtagagca gctgatcttt ttggtcgcta cagcatggtg atcattttag
    43021 cgggactact tattgcgttt caattgatga cggatggtat tttctggcgt ccattgaata
    43081 taactaacct tgttctgcaa aatagccata tattagtact agctgcaggg atgttattag
    43141 ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt gatggcgttt gttggtgcaa
    43201 ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg gatgacagtt atcgcatgtc
    43261 ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg ggtagcttat gcagggatac
    43321 cggcgtttat cgtgacttta gcaggattgc tgatgtttcg tggactgaca caagttgttc
    43381 taggaggcca atctctagca ccttttccag ctgttttcca aaaaatgtct acgggttatt
    43441 taccagactt aagcgaagga agcagccttc acttcttgac attgatttta ggaatgatca
    43501 tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa tcgtcggaaa aatcatttat
    43561 ttgaagtgga atctccaaca gctttcttgg taaaggcggt atttacagca gtcgttgtac
    43621 taggaataac ttatatcttt gcctcttatc aagggtatcc gattattttg atcattcttg
    43681 gtttgatcgt tgcagcatat gggtttttga caaataaaac agtagcaggt cgacagattt
    43741 atgcgacggg cggaaatcga aaagcggctg aactatcagg gatcaaaaca aagcgaatca
    43801 cgttctgggt attcgtcaac atgggagtca tggcagcttt agctggatta gttttagctg
    43861 ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat ggaactggat gcaatggcgg
    43921 cagtatattt tggtggtgct tcgacttccg gcggcattgg aacaatcatg ggtgcgattg
    43981 tcggtggctt ggtcatgggt gtattgaaca atggcatgtc gattttaggc gtcggggtag
    44041 actggcagca ggcaatcaaa ggattgatct tgcttttagc cgttgtgcta gacttgtata
    44101 ataagaaaaa acgaacaacg taggagaacg ccggttattc agaaaaaaga ctgtgacaag
    44161 acatttgtca cagtcttttt ttcgctaaaa gcgaacattc attgtttcgt ttgtatagac
    44221 taaaaataat atatgttttt ttaccattcg tataaattct ctttttgctc ttgatttttt
    44281 tgcttaattg agttaaatta catagggcgc taaaaaaagc cttgattaaa ttaataatgt
    44341 tcgtgttttg ctggatgtga acatcaggag gataatgtaa tgaaagtatt tgattacgaa
    44401 gatattcaat taattcctaa taaatgtatc gtaaatagcc gttctgaatg tgatacaacg
    44461 gtcacattag gtaaacatac attcaaaatg ccagtagtgc ctgccaacat gcagacgatt
    44521 attgatgaaa caatcgcaga attcttagcg gaaaatggtt atttctatat catgcatcgg
    44581 tttgatgaag cagctcgaat tccgtttatc aaaaaaatga aaaagcgtgg attgattacc
    44641 tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta tagagaagtt ggcagaagaa
    44701 tcgctaaatc ctgattatat cactatcgac atcgcgcatg gacatgctaa ctcagttatt
    44761 gatatgattc agcatattaa aaaatatttg cctgaaactt ttgtgattgc cggtaatgtt
    44821 ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg cagatgcaac aaaagtcggg
    44881 attggtccag gaaaagtatg tattacaaaa atcaagacag gctttgggac tggaggctgg
    44941 caactggcag ctcttagatg gtgtgcgaaa gcagctcgca agccgatcat cgctgacggt
    45001 gggatcagaa cacatggcga tattgcaaaa tctgtccgtt ttggtgcgac aatggtcatg
    45061 attggttcat tgtttgccgg tcacgaggaa tctcctggcg aaacaaaagt cgaaaatgga
    45121 atcgtgtata aagaatactt tggttctgct tcagaattcc aaaaaggcga aaaacgaaat
    45181 gttgaaggaa agaaaatctg gatccaacac aaaggatctt tgaaagatac actagtggaa
    45241 atgcaacaag accttcaatc atctatttct tatgctggag gaagagatct ggaagccatt
    45301 cgaaaagttg actatgtcat cgtgaaaaat tcgattttta atggagacac aatctaaaaa
    45361 ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc attaagtaat aagaacagcc
    45421 aaacaaaaat agttctttat atgttttgtt tggctggaat tattatcgca gatacaagct
    45481 tttgaacatc attattcaga ataagggact gtgataagat ttttgtcaca gtcccttatg
    45541 ttttgcaaaa aaagtttttc ttttttctcg taaattcggt aaaatcaaaa gaaaaaatag
    45601 acaatagaaa agagaagctt atgtgggaaa aagtagagaa aaaacaagga ccgatttatc
    45661 gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg aaggatcaat cctggaagtc
    45721 aacttgaatc agaacgaaaa ctagggcaac tttttggtgt gaatcgttcc accgttgtcc
    45781 atgcattgga agagcttagg gagcttgggg tactaacgag caaacgtggc agcggatggt
    45841 ttgttaatca gactgaatgg gggaaattcg ctgttccaag aatcgattgg cggcaaatga
    45901 tctctcctcg ttatgagcag acggactggt atgagcaaaa aataagagaa gcaaagcaga
    45961 tccaaaaaac atcgtttctt gatttatacg ctagcgagat gccagatgag cttttgccga
    46021 attttgagtt tccttcttat tctcttgaag aaatcttagc ggaagaaaaa gaaatggatc
    46081 ttttaggcta tactccgtta cgtaacaaaa tcaaacggta tttggaaagt aaatttgaat
    46141 tggcattttc ccccaaccag cttcttgtga ctggtggcgg tcagcaagca atctttttga
    46201 ttttacaaac gattctttca gctggagagg ggatagctgt agagtcacct tctttttttt
    46261 accgattacc tcttttcaaa gcttcaggaa cgcgtttatt tgggataccg atggatgaag
    46321 aagggatcga cttagaaaaa ctgaaagaat cgatccataa aaataaattg aaagcagtgc
    46381 ttatcaaccc gaattttcaa aaccctacag gaaaagtgat gagtcaaaaa cgacgagaaa
    46441 agctagtaga attgtgtcga cagtatcggc ttccaattat tgaagacgat gtatttacgg
    46501 atctttcatt tctaaaccaa gaagaagtcc ttcctatacg aacgattgat ccggataatg
    46561 tgttatacgt cggttcgtta tctagggttt taggaaaaac aacgaaaatc ggttgggtga
    46621 taggacctga gacttttatc tcgcaactag ctcaagcgca agaaatgatg gagttttcga
    46681 tgaatatcct tacacaaatc acagtggcta atgtatttaa tgaagcaatt gatttgaaaa
    46741 tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact gataagcgct tggggagatt
    46801 cacaatcgtt tttcaagctt cattcaattt taggtggtta ctatgcctgg attacttggg
    46861 atgggaaaaa actagacccc gaactagcag aaaaagtagt agatatgggt cttggaattg
    46921 caccaagtct actttttggg caagatataa atggaatcag aatcaattac agtaggctgg
    46981 atgaaaacca aataccgttg ttttattcaa agatgaaaat tctagaaaag tggttaacag
    47041 aataatttca caaagtaaat agattaaaga atataacagc ttggatttaa atttcaagct
    47101 gtttcttttt tttcggaaaa agaatacgat ataaagaaac taagaaaaaa ccattatttg
    47161 tacgtccgtt cacgatgtgt aaataaaata aatgtttgca acaaaactgt ataacaccaa
    47221 cgtttttaaa tagaaacaga tggttgtaag tttgattaga aaatagaaaa aatgcagatg
    47281 aaatataaaa cgctttcctt attgtgattt tattcactaa tgctgttaat atgcggattg
    47341 gcataatttc ctttcatcgt gaaaatttgt gcttttagct tgtatttctc ataaatccat
    47401 gataatttat taatgaagac ggttaaatag tgatacagtt ttattcactg tttcaatcgc
    47461 agaatgaaga gattttctta tagatgagag aggaatgtgt gacaaatggc aaacaaaaaa
    47521 gcaccgatcg acttccaagc actgctagat gaagtcaatg cagatttccc agtatatcaa
    47581 gcacttgatc aagatggaaa cgtagttaac aaagatttag tacctgattt atccgatgat
    47641 gaactcgttg aattaatgac tcatatggta tggtctcgtg tattagacca acgttcaaca
    47701 gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa ctgctggaca agaggcaagt
    47761 cagctggcta gtgcttacgc atttgataaa gaagatgttc ttcttccagg ttatcgggat
    47821 gtacctcaac tagtaaaaca tggtttacct ttatctcaag cttttttatg gtctcgagga
    47881 catgctgcag gtaattctta tccggaagaa ttgaaagctc taccaccaca aattatcatc
    47941 ggtgcacaat atgtacaagc agccggtgtt gcattaggtt tgaagaaacg aaacaagaaa
    48001 aatgtcgtct tcacttatac tggtgatggc ggttcatcac aaggtgattt ttacgaagca
    48061 atcaatttcg ctggcgctta ccatgcaaat gccgtatttt atatccaaaa caacgggtat
    48121 gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa cacttgcaca aaaagctgtc
    48181 gcagctggga ttcctggtat tcaagtcgat ggaatggatc cgcttgcagt atatactgta
    48241 tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac cagtcctaat cgaaacactg
    48301 acttatcgtt atggaccaca tacactatct ggtgacgatc caacccgcta ccgtacaaaa
    48361 gacacagatg acgattggca gaaaaaagat ccattgatcc gcttccgtaa atatttgacg
    48421 gaaaaaggac tttggtctga agaaaaagaa gaacaagtca tcgaagcaac taaagaagaa
    48481 atcaaagcag ctattgctga agccgacaaa gtaccaaaac aaaaggtttc agatttcttg
    48541 aaaaacatgt tcgaagtatc tccacaatca atcaaagaac aaattgcaat ttatgaagcg
    48601 aaggagtcga aataatcatg gcacaaaaaa caatgatcca agcaatcaca gatgccttag
    48661 cacttgaact agaaaatgac gagaatgtcg ttgtttttgg tgaagatgtt gggaaaaacg
    48721 gaggagtttt ccgggcaact gaaggattgc aggaaaagtt cggagaagac cgagtattcg
    48781 atactccttt agctgaatct ggaatcgcag gattgagttt cggtcttgcg ttagaaggat
    48841 ttcgtccagt tcctgaaatc caattctttg gttttatttt cgaagcaatg gacgaagtag
    48901 tagctcaaat ggctcgtaca agatatcgaa tgagcggcac tagaaatcta cccatcacaa
    48961 ttcgttcgcc atttggtggc ggtgttcata caccagaatt gcattcggat aatttagaag
    49021 gtttgatcgc tcagtctcct ggtattcgag tagtgattcc ttccaaccct tatgatgcaa
    49081 aaggactatt gatttcttct attagaagta acgatccggt tgttttccta gaacacatga
    49141 aactatatcg ctcattccga gaagaagtgc cggatgaagc ttacgaagtt cctttggata
    49201 aagcagcagt tactcgtgag ggaacagatg tatctattat cacatacgga gcaatggtgc
    49261 gtgaagcaat caaagcagca gacaatcttg caaaagaaaa tatatctgtt gaaatcattg
    49321 atcttcgtac agttgcgcca ttagatgtag aaacgatcat tcaatccgtg gaaaaaactg
    49381 gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg cgttgccgcg caagtagttt
    49441 ctgagatctc agaacgcgct atcctttcat tagaagcccc aatcggacga gtttctgcac
    49501 ctgatacagt cttcccattt ggacaagcag aaaatgtctg gttgccaaat gcaaaagata
    49561 tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa gaagggacga aacaaagtca
    49621 tggcttatca atttaaattg ccggatatcg gtgaaggaat cgcagaaggt gaaatcgtca
    49681 aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta gaagttcaaa
    49741 atgacaaatc agtagaagaa atcccgtcac ctgttacagg aacggttaaa aatgtgattg
    49801 ttccagaagg taccgtagca aatgttgggg atgtattagt agaaatcgat gcaccaggac
    49861 acgaagacaa tgaaggggac agtggtgtag ccgcagaatc ccaaactcca gctaaaccgg
    49921 ctgctgaacc cactgttgat acagaatcag ctggatcgtc aagcgaagga gtcttccaat
    49981 ttaagttacc ggatatcggt gaaggaatcg cagaaggtga aatcgtcaaa tggttcgtca
    50041 aaccaggaga tacgatcaat gaagatgata cattactaga agttcaaaat gacaaatcag
    50101 tagaagaaat tccgtcacct gtcacaggga cagttaaaaa cgtgattgtt ccagaaggca
    50161 ctgtagcaaa tgttggggat gtattagtag aaatcgatgc tcctggacac aatagtgcac
    50221 cgtcaactag tgcgccatca gctgaagcac caaaagaaaa agtggaaaca tcaggttcag
    50281 caagtgtcgt tgaagctgcc gatccaaata aacgtgtatt ggctatgcca tctgttcgtc
    50341 aatttgcccg tgaaaaagat gtagatatct cacaagtaac tgcaactgga aaaggtggca
    50401 gagtaacaaa agaggacatc gaaaacttct tggcaggtgg tccaagcagt gcaccagcga
    50461 aatcagaagc gccagaagcg gcagcaccga aagaagcagc tcctgcagca gaaagcaaac
    50521 cagctgcacc agcaaaacca ttcaagtcca acttaggaga cttggaagaa cgtgtagcaa
    50581 tgacgccaac acgtaaagct atcgctaaag caatggtcaa cagtaagcat acagctccac
    50641 acgtgacatt gcatgatgaa gtagaagtgt ctaaactatg ggataatcgg aaacgattta
    50701 aagaagttgc tgctgcaaat ggtacgaaac ttactttctt gccatatgtc gtgaaagctt
    50761 taacagcgac tgttaagaaa tacccagtat tgaatgcatc tatcgacgat gcaaaccaag
    50821 aaatcgttta taaacattac tacaatatcg gtattgcaac tgatacggat cacggactat
    50881 atgtaccaaa tgtgaaagat gcagaccgca aaggaatgtt tgctattgca gacgaaatca
    50941 atgagaaagc aaaattagct catgacggca aactatctgc agaagatatg cgcaatggaa
    51001 caattacgat cagcaatatc ggatctgtag gtggcggttg gtttacacca gtcatcaact
    51061 atccagaagt agctatttta ggtgtaggaa cgattgcaca acaaccaatc gtaaatgctg
    51121 aaggcgaaat cgttgtcggt cgtgtgatga aactgtcatt aagtttcgat caccgtatcg
    51181 tagatggagc aactgcgcaa caagcaatga ataatatcaa acgtctttta gctgatccag
    51241 agctattaat gatggaagga tgataaacaa atggtagttg gagattttgc tgtagaatta
    51301 gatacagttg taattggtgc gggacctggt ggctatgtag ctgccatccg cgctgctgaa
    51361 atgggacaaa aagtagcaat cattgaaaga gagtatattg gcggtgtttg tttgaatgtc
    51421 ggctgtattc cttcaaaagc actgatagct gcaggacacc attatcaaga gtcactagat
    51481 tctgaaatgt ttggagtaac tagtgaaaac gtcaaactag attttgcaaa aacacaagaa
    51541 tggaaagaaa acaaagttgt ccatacgttg acttctggtg ttggtttcct attaaaaaaa
    51601 cataaggttg aaacaatcga aggagaagcg ttcttcgtag atgatcacac actacgcgtc
    51661 attcatccag attcagctca aacttattcg ttcaataacg caatcatcgc aacaggttcc
    51721 cgtccaatcg agattccagg atttaaattc ggaggacgtg tgttagattc tactggcgga
    51781 ttagcattga aagaagtacc taagaaattt gtgatcatcg gtggcggtgt gattggtgcc
    51841 gaattgggcg gagcgtacgc aaacttagga gcagaagtaa cgattcttga aggctcacca
    51901 caaattttac caacttacga aaaagatcta gtaaaattag tagaagatga tttcaagaaa
    51961 aaaggcgtaa cagtcgtaac gaatgcaatg gcgaaagaag cagtcgataa cggtgacagc
    52021 gtgacagtga aatatgcagt ggacgggaaa gaagaatccg ttactgctga ttatgtgatg
    52081 gtcactgtag gtcgtcgtcc gaatacagat gatatgggct tagaacaagc gggtgtcgaa
    52141 gtaggagaac gaggattgat cacggtggat aaacaaggac gtacgaacgt acctaacatc
    52201 tatgccatcg gtgatatcgt tccaggggcg gcattagcac acaaagccag ttatgaagca
    52261 aaaatcgctg ctgaagcaat ctctggcaaa aaagtagctg tagattataa agcaatgccg
    52321 gcagtagcct tcactgatcc tgaattggct tctgtaggta tgacgatcaa agaagcaaaa
    52381 gatgctggta tcgaagcaaa agcatataaa ttcccatttt cagggaacgg tcgggcatta
    52441 tcgcttggta aaacagaagg attcatccgt ctagttacga cgatcgaaga taacgtgctt
    52501 attggcgcgc aaatcggtgg agtcggcgca agtgatatgg tctctgaatt agctttagca
    52561 atcgaatcag gaatgaatgc tgaagatatc gccttgacga ttcatcctca tccatctctt
    52621 ggcgaaatcg tcatggatgc ttcggaatta gcattaggtt taccaatcca tatttgattt
    52681 gaataata
//
LOCUS       DAFELK010000014        50277 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFELK010000014
VERSION     DAFELK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50277
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.015"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            577..3216
                     /locus_tag="LP433_001034"
     CDS             577..3216
                     /locus_tag="LP433_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2005214.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3384..4082)
                     /locus_tag="LP433_001035"
     CDS             complement(3384..4082)
                     /locus_tag="LP433_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL2005215.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4300..5445
                     /gene="tgt"
                     /locus_tag="LP433_001036"
     CDS             4300..5445
                     /gene="tgt"
                     /locus_tag="LP433_001036"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBL2005216.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5542..5922
                     /gene="yajC"
                     /locus_tag="LP433_001037"
     CDS             5542..5922
                     /gene="yajC"
                     /locus_tag="LP433_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBL2005217.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6227..8824
                     /gene="adhE"
                     /locus_tag="LP433_001038"
                     /gene_synonym="adhC"
     CDS             6227..8824
                     /gene="adhE"
                     /locus_tag="LP433_001038"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBL2005218.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9053..10159
                     /locus_tag="LP433_001039"
     CDS             9053..10159
                     /locus_tag="LP433_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL2005219.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10176..11204
                     /locus_tag="LP433_001040"
     CDS             10176..11204
                     /locus_tag="LP433_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBL2005220.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11210..11689
                     /locus_tag="LP433_001041"
     CDS             11210..11689
                     /locus_tag="LP433_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBL2005221.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11705..13000
                     /locus_tag="LP433_001042"
     CDS             11705..13000
                     /locus_tag="LP433_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBL2005222.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            13011..13835
                     /locus_tag="LP433_001043"
     CDS             13011..13835
                     /locus_tag="LP433_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL2005223.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            14000..14899
                     /locus_tag="LP433_001044"
     CDS             14000..14899
                     /locus_tag="LP433_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005224.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15025..15894)
                     /locus_tag="LP433_001045"
     CDS             complement(15025..15894)
                     /locus_tag="LP433_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005225.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVDIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16047..17507
                     /gene="rhaB"
                     /locus_tag="LP433_001046"
     CDS             16047..17507
                     /gene="rhaB"
                     /locus_tag="LP433_001046"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBL2005226.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17504..18760
                     /gene="rhaA"
                     /locus_tag="LP433_001047"
     CDS             17504..18760
                     /gene="rhaA"
                     /locus_tag="LP433_001047"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBL2005227.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18774..19619
                     /gene="rhaD"
                     /locus_tag="LP433_001048"
     CDS             18774..19619
                     /gene="rhaD"
                     /locus_tag="LP433_001048"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBL2005228.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19621..19932
                     /gene="rhaM"
                     /locus_tag="LP433_001049"
     CDS             19621..19932
                     /gene="rhaM"
                     /locus_tag="LP433_001049"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBL2005229.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            20014..21165
                     /gene="fucO"
                     /locus_tag="LP433_001050"
     CDS             20014..21165
                     /gene="fucO"
                     /locus_tag="LP433_001050"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBL2005230.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21292..22050
                     /locus_tag="LP433_001051"
     CDS             21292..22050
                     /locus_tag="LP433_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBL2005231.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22150..22794
                     /locus_tag="LP433_001052"
     CDS             22150..22794
                     /locus_tag="LP433_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBL2005232.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22801..23808
                     /locus_tag="LP433_001053"
     CDS             22801..23808
                     /locus_tag="LP433_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL2005233.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23824..24666
                     /gene="kduI"
                     /locus_tag="LP433_001054"
     CDS             23824..24666
                     /gene="kduI"
                     /locus_tag="LP433_001054"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBL2005234.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24686..25489
                     /locus_tag="LP433_001055"
     CDS             24686..25489
                     /locus_tag="LP433_001055"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBL2005235.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25738..26802)
                     /locus_tag="LP433_001056"
     CDS             complement(25738..26802)
                     /locus_tag="LP433_001056"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBL2005236.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26799..27884)
                     /locus_tag="LP433_001057"
     CDS             complement(26799..27884)
                     /locus_tag="LP433_001057"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBL2005237.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27897..28874)
                     /gene="mvaD"
                     /locus_tag="LP433_001058"
     CDS             complement(27897..28874)
                     /gene="mvaD"
                     /locus_tag="LP433_001058"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBL2005238.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNFKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28867..29811)
                     /gene="mvk"
                     /locus_tag="LP433_001059"
     CDS             complement(28867..29811)
                     /gene="mvk"
                     /locus_tag="LP433_001059"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBL2005239.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30127..30786
                     /locus_tag="LP433_001060"
     CDS             30127..30786
                     /locus_tag="LP433_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL2005240.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            30871..31776
                     /locus_tag="LP433_001061"
     CDS             30871..31776
                     /locus_tag="LP433_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL2005241.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31778..32410)
                     /locus_tag="LP433_001062"
     CDS             complement(31778..32410)
                     /locus_tag="LP433_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL2005242.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    32561..32686
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            32730..33254
                     /gene="infC"
                     /locus_tag="LP433_001063"
     CDS             32730..33254
                     /gene="infC"
                     /locus_tag="LP433_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBL2005243.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33326..33526
                     /gene="rpmI"
                     /locus_tag="LP433_001064"
     CDS             33326..33526
                     /gene="rpmI"
                     /locus_tag="LP433_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBL2005244.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33579..33938
                     /gene="rplT"
                     /locus_tag="LP433_001065"
     CDS             33579..33938
                     /gene="rplT"
                     /locus_tag="LP433_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBL2005245.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34190..35527
                     /locus_tag="LP433_001066"
     CDS             34190..35527
                     /locus_tag="LP433_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBL2005246.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35575..37704
                     /locus_tag="LP433_001067"
     CDS             35575..37704
                     /locus_tag="LP433_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBL2005247.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37679..38368
                     /locus_tag="LP433_001068"
     CDS             37679..38368
                     /locus_tag="LP433_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005248.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38776..39462)
                     /locus_tag="LP433_001069"
     CDS             complement(38776..39462)
                     /locus_tag="LP433_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2005249.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(39598..39792)
                     /locus_tag="LP433_001070"
     CDS             complement(39598..39792)
                     /locus_tag="LP433_001070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005250.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39842..40282)
                     /locus_tag="LP433_001071"
     CDS             complement(39842..40282)
                     /locus_tag="LP433_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBL2005251.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40286..41131)
                     /locus_tag="LP433_001072"
     CDS             complement(40286..41131)
                     /locus_tag="LP433_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBL2005252.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41280..42698
                     /gene="pepV"
                     /locus_tag="LP433_001073"
     CDS             41280..42698
                     /gene="pepV"
                     /locus_tag="LP433_001073"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBL2005253.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42755..43702)
                     /locus_tag="LP433_001074"
     CDS             complement(42755..43702)
                     /locus_tag="LP433_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2005254.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43925..44275)
                     /locus_tag="LP433_001075"
     CDS             complement(43925..44275)
                     /locus_tag="LP433_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL2005255.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44475..45554
                     /gene="pepA"
                     /locus_tag="LP433_001076"
     CDS             44475..45554
                     /gene="pepA"
                     /locus_tag="LP433_001076"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBL2005256.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45698..46018
                     /locus_tag="LP433_001077"
     CDS             45698..46018
                     /locus_tag="LP433_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL2005257.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            46040..46504
                     /locus_tag="LP433_001078"
     CDS             46040..46504
                     /locus_tag="LP433_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2005258.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46709..47314
                     /locus_tag="LP433_001079"
     CDS             46709..47314
                     /locus_tag="LP433_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBL2005259.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47353..48642)
                     /locus_tag="LP433_001080"
     CDS             complement(47353..48642)
                     /locus_tag="LP433_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBL2005260.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            49070..49549
                     /gene="rlmH"
                     /locus_tag="LP433_001081"
     CDS             49070..49549
                     /gene="rlmH"
                     /locus_tag="LP433_001081"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBL2005261.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            49752..50277
                     /locus_tag="LP433_001082"
                     /pseudo
     CDS             49752..50277
                     /locus_tag="LP433_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336126.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
BASE COUNT        15970 a         9125 c        10755 g        14427 t
ORIGIN      
        1 caaagatttt atgacaaaga aaaagccgag ctctcgataa gctcggcttt cttgtacctc
       61 ggaaggattc aaataaacag aaatgattgt aactttccat catacatgca aagcacggtg
      121 ttgaatttct tcatgttaaa caaaaatttt gttttcgtta catcttcaac atttgaaaca
      181 tctcttgttc ctattcaatt ttcagacgtt tacgttattc aattgttacg tatcgcatta
      241 cttcttgttt cggatacttc gtgatccaaa catccatacg cattcactat ttataggttt
      301 gtactctaca cgcatgtctg ggtgaaacct gtacttctaa caactttgtt tgcttacact
      361 gttctatcga gaaattcttc tgtctatttg atggtatcct ccttccttac atctatataa
      421 tagcatcctt tggtagcgtt tgcaaatata agcactttaa attttacgct ttcttaacaa
      481 ataatcgata agccctttat ttgaagtaaa taaaaaaagg atgttatagt aaaataagta
      541 cctttttttg tacgaagatt ttaaaggagg aataggatgg aagaatacaa gcagacaata
      601 gaagaagtaa agaaggtaac agaagcagat ccagatactg ggttgtcttc acaagaagtg
      661 gatgaacggc gaaaaaagca gggattgaat aaattcgatg aggcgccgaa agaatcgatg
      721 atcaaaaaat tctttcgaag cttgtccgat tttacaacga tcatccttct tgtagcagcg
      781 gtgatttcct tttataccgc atttgctaca gaacatgggg atttatttga aggactgctg
      841 atcatcgcta tcgttgtgat caactcggta ttggcgattg tccaagaagg aaacgcagaa
      901 aaagcactgg aatccttgca agatatgaat aaacaaacgg caactgtcat acgagacggc
      961 aaagtgacca ctgttgagtc agagcaactg gtagtgggtg atattcttgt tttagagtcc
     1021 ggtgatgcta tttctgccga tgcccgtttg atcgaagcat cacaattacg tgtagaagaa
     1081 tcggcgttga ctggagaaag tgaagcagtt gaaaaagatg cagcatttat tgctgaagaa
     1141 gatgagtcat taggtgacca acttaatatg gtatttaaag gatgtacggt tgctgcaggt
     1201 cgtgggaaag cgatcgtcac tgccattggc atggctacag aaatgggtaa gatcgcggat
     1261 cttttgaacg aaaatactat gcaaaaaaca cctttacagg tccgattgaa tcagctaggc
     1321 aaacgaatca gtatgatcgc tttagcggct gcggctttag tatttgtgat tggtgaactg
     1381 caaggagaac cactccttga gatgttcatg acttcgattt ccttggctgt tgcagctgta
     1441 ccggaaacct tgactgttat tgttacgttg acacttgcat acggtgtgca gaagatggcg
     1501 aggaaacatg cgatcatccg acagttgcca gcagttgaaa cgctaggaac cgctaatgtt
     1561 atctgctcag acaaaacagg aacgctgaca caaaatgaaa tgcgcgtccg ccgggtatgg
     1621 agcaaagaag atgaagtaac gaatatcgaa gattcaatga cgaacagcgc gatggaaata
     1681 ttgaaaatgg ctgcactatg tacagatgtg acggtcgagc aagaagatga cgaccttgtt
     1741 atcaaaggta atccaacaga agtagccatc gtaagggctg ttgaagagaa ttatcataca
     1801 aaggcagaat tagaagaaaa atatccacga gtaaacgagc ttccttttga ttctgaacga
     1861 aaaatgatga caacagttca ccaaatgggc gaaaaataca tctcaatcac caaaggagca
     1921 ttcgatgttc ttgctccgcg ctttagttca ggcgatgtag aacaagcggc gatcgttaat
     1981 gatcgctttg gtaaacgggc actgagagtg attgctgttg gttatgctac ttatgacgaa
     2041 gaaccgcaag atatttcttc tgaagcactg gaaaaagact tacgtttgat tggtctgatc
     2101 ggaatgatcg atccaccacg tccagaaagt aaaggagcaa tcaagcgagc gaaaaaggct
     2161 ggcatcaaaa cagtcatgat cactggagat catgtggtga ctgccagtgc catagcgaaa
     2221 gaattaggta tcttgaatga tccgtcagaa gcactttcag gatcagaact gcatcaatta
     2281 tcagacgaag aattagatgc gcgtgtcaaa gctctctctg tctatgctcg ggtaacgcca
     2341 gaagacaaga tccggatcgt caaatcttgg caacgtacgg gtgcagtcgt agcgatgact
     2401 ggggatggtg tgaatgatgc accagcgttg aaagcaagta acgttgggtg tgccatgggg
     2461 atcacaggaa cagatgtggc gcaaagtgcc gcagatatga ttttgacgga tgacaacttt
     2521 gcgacgatcg tagacgctgt cagtcaagga cgttcggttt atcagaatat tcgtaaagct
     2581 atcaactttt tgctaagctg taatatttcg gagatcttta ttgttttgat tgcgatgctg
     2641 ttaggatggg gagcaccatt tacagctgtg caactactgt ttgtcaatgt agttgctgat
     2701 ggacttccag gatttgcttt aggaagagag ccagcggaac acggcatcat ggatcagcca
     2761 cccattccga aaaatgaagg gatctttgct cgaggtttat tgcaaaaaat tgccataaat
     2821 gcaggggtct tcaccatcgt aaccttgttt ggttattatt taggtagtta tgtcgatact
     2881 atcagcccat gggtagacgc aagtcagcat gtcggtcaaa ctgttgcatt cttgatctta
     2941 gcttattcat cgattctgca tgtgttcaat gtacgcagca gccaatcgat cttcaaagtc
     3001 aatttagcga ccaataaagc tttggtagaa atggcgttac tggcattagc tattacaacg
     3061 gctgttgctt tgctgccatt tacgcaagaa ctattcggcc tagtacacat cagtttgaat
     3121 cactggttct tggtagggat tttatctatc gtaccaatcg cggtgaatga actgatcaag
     3181 ttccatcgat taccggaagc agaagaagag gaatgattaa ctgtttctaa gttgattttc
     3241 tttttactgg aactatacaa aaaggaggtg tgacatgaat gttgtcacac ctcctttttg
     3301 ctaatgggct gaatgtttct tttactgcct ctcgataaac ggtgttctcc tgccaccccc
     3361 tcggtcacaa gtcacactct cttttaaata tcttttggca attgttcata aaatgctgct
     3421 tttgttgcag aaatgtatgg gctgagccat agataaccaa taccagcagt tgctaatgct
     3481 aagatatgcc agccgataaa tgaaagatct aaccagaaaa gttgtccttt ataaccatcc
     3541 atcaattttc gacttgcagt gatcgtatcc agtactttag gtgtttgtcc tgtttcttgg
     3601 acgatatcgt agtaaataaa atagctttga gaataagaat agcttttaat gattccagga
     3661 ataactaata gcaaacccca taatgttgta aagatcgaga tcagcacagc taagctgatc
     3721 actccgccga taaacaaacc tttgaatcca cgaaatgcat ctttgaatgg ttcgatctga
     3781 tctttttgtc cacgtaaaat atcaagataa gtccaagaaa taccgctcat gaacaaagcg
     3841 ctaatgatgc tggaaataat tccgccaccg cctcctgaac taccgcctcc tgaagttgtc
     3901 gcttctgaga cgctcgctga tccatcatat atggtggtgg caaacaagat aataggaatc
     3961 ataataagaa gaatagtagc aataccaatc aatgtaggga ttagatttag taaaacagct
     4021 tgtccccaac gtccttttag actctctttt gcttggcgtt ttaattctgc agaagattgc
     4081 atgatttttc cctccttttc tttaataaca ccaatatacc atgtatcaaa aaatatttct
     4141 gtcataatgt ttttcttttt tttgttattc ataaaaaaag gataaaaaaa agaatattaa
     4201 ataaagtaga aggaagccga gggaacttgc aaaaagcact tgaaacgatt atgatggtgg
     4261 gagttgtcaa gatattttat atagaaagta gggaaatgaa tgacgcaacc tgccattcgc
     4321 tatcgtttaa tcaagaaaga aaaacatact ggcgcgcgtt taggggaatt gatcacgcca
     4381 cacggaactt tccccacacc aatgttcatg ccagtaggaa cattagctac agtaaaaaca
     4441 atgtccccag aagagttgaa agaaatgggt gctggcgtta ttttaagtaa tacatatcat
     4501 ttatggctac gccctggtga agacttagta gaagaagctg gcggactgca taaatttatg
     4561 aactgggatc aaccgatttt aacagattca ggcggctttc aagttttttc attaagtgat
     4621 atgcggaata tcgaagaaga aggcgtgcat ttcaaaaatc acttgaacgg ttcgcgtatg
     4681 tttttatcac cagaaaaagc aatcaacatc caaaataaat tgggctctga tatcatgatg
     4741 agttttgacg aatgtccacc attcgatgaa agttacgact acgtgaaaaa atcagtagaa
     4801 cgtacgtctc gatgggcaga acgaggattg aaagctcatg ctaatccaga ccgtcaagga
     4861 ttatttggaa tcatccaagg agcagggttt gaagatcttc gtcgtcaaag cgcgaaagat
     4921 ctagtcggga tggatttccc tggttactca atcggcgggt tatctgtcgg ggaacctaaa
     4981 tcagaaatga atcgtgtatt agaattcact acaccgttga tccccgaaaa caaaccacgt
     5041 tacttgatgg gtgtcggtgc tgctgattca ttgatcgatg gtgttatccg tggagtagac
     5101 atgtttgact gtgtcttgcc tactcgaatc gctcgaaatg gcacatgtat gacttctcaa
     5161 ggccgtctag tagtgaaaaa tgcgaaatat gcccatgatt tccgtccaat tgatgagaaa
     5221 tgtgattgtt atacatgtaa aaactataca cgtgcctata tccgccattt gatcaaatgt
     5281 gatgaaacat ttgggattcg tttgacttct taccacaatt tatacttctt gttgaatcta
     5341 atgaaacaag tacgtcaagc aatcatggat gataatttgc ttgaatttag agaagccttt
     5401 tttgaagaat acgggttcaa taaagaaaac gcaaaaagct tctaaaggaa aatcttttaa
     5461 aaattaagta aaaaactagt gttatcagca tttttctgct aaagtgtttt ttgtagatac
     5521 agaattagtg aggtgaaaaa aatgggaaca ttaccaatgc ttgtgatgtt tatcgcgcta
     5581 ttagcaatgt ggttttttat gtcacgttcg caaaagaaac aacagcaaga acgtcaaaac
     5641 ttgttagata gcatgaaacc aggtgattca gtcgtaacga tcggcggatt acatggagtt
     5701 gtttcagaaa tcgacaatga caaacggaca gttgttttag actgcgaagg gatcttcctt
     5761 gagtacgatc gtgcagcaat caaaacggtc aaaccaggga ctgtcgtaac aaatgatgca
     5821 acgactactg ttgaaacaac agaagaacca gctgagacag ttgaagtaaa aactgaaaca
     5881 acagaaacgc tggaagagac agaagagaag gaagaaaaat aagtatcaaa gcttatttaa
     5941 agacgaggta gggcagaaag atgtcctacc tcatttttta ttcaaaaaag aaagagataa
     6001 gagcatggga tatattgctc aatattgaat aatcgggtgt gtcatataaa taataataaa
     6061 taactttata tatttttcta tacaaacacc tgtaaataaa gcaattttat atttaaaaat
     6121 aactgtgaaa aaaatcacaa aaaagtgttt acatagaaaa ataaatattg tatgatatac
     6181 atgtgaatta tttaacaaat aaccatgacc cattaggagg ataatgatgg ctaaagtaat
     6241 agaaaaagaa aaaacgaaga caattgacgt acaagcaatg attgatgatt tggcagaaaa
     6301 agcaaatgca gcattgaaag aaatggaaag ctttgatcaa gaaaaagtag accatatcgt
     6361 gcatgaaatg gcaatggcag ctttggatca acatatgcca ttagcgaaga tggctgtaga
     6421 ggaaacaggc cgcggtgttt acgaagataa agcaatcaaa aatatgtatg cgtccgaata
     6481 tatttggcat aatatcaaac atgataaaac agttggtgtg atcaatgaag atgtccaaaa
     6541 agggttgatt gaaattgctg aaccagtcgg tgtggtttgc ggagtaactc caacaacgaa
     6601 tccgacttcc acaacgattt tcaaatcaat gatcgcgttg aaaacaagaa atccaatcgt
     6661 ttttgctttc catccaagtg cccaaaaatc ttctgcagaa gcagcacgag tggtacgtga
     6721 tgctgctatc gctgccggag ctcctgaaaa ttgtatccaa tggatcgaac atccttcgat
     6781 cgaagcgact tctatgctaa tgaaccatcc aggtatcgcg atcgtcttag cgacaggtgg
     6841 agctggaatg gtcaagtctg cttactctac aggaaaacca gctttaggtg taggtccagg
     6901 taacgtacca gcttatattg aaaaaacagc aaaaattaaa cgtgcagtga acgatttgat
     6961 cgtttcgaaa acatttgata atggaatgat ttgtgcttct gaacaagctg tgatcgtgga
     7021 taaagaaatc tatgcagcag taaaagcaga attccaagca caccaagttt atatcgtaaa
     7081 accagatgaa ttgcaaaaat tagaagatgc agtgatgaac gaaggaaaat atgcggtcaa
     7141 tccatcaatc gttggacatt ctgcgatgga aatcgcaaaa ttggcaggaa tcagtgtacc
     7201 aaaaggaacg aaaatgctga ttgctgaatt ggaaggcgta ggcccagatt atccgctatc
     7261 aagagaaaaa ctttctccag ttcttgccat gatcaaagct aacaacacgg accatgcgtt
     7321 tgatttgtgt gaaggtatgt tgaatcttgg aggattagga catacagcag ttatccattc
     7381 agaaaacgaa gagttgcatg tcaaattcgg tcttcgaatg aaagcttgtc gtattttagt
     7441 gaatacacca tctgcagaag gcggcatcgg tgatatctat aacgaaatga ttccgtcatt
     7501 gactttggga tgcggttctt atggtaagaa ctctgtttct cgtaacgtct ctgctgtaaa
     7561 cttaatcaat gtcaaaactg tagcgaaacg gagaaataac atgcaatggt tcaaattacc
     7621 gccaaaaatc ttctttgaaa agaactctct attgtactta gagaaaatgg aaaacgttga
     7681 acgtgtcatg atcgtttgtg accctggtat ggtccaattc ggttactgcg atacagttcg
     7741 tgaagtattg gcacgacgta aaaatgatgt gaagatcgaa gtcttctcag atgttgaacc
     7801 gaacccatcg acaaataccg tatacgcagg aacgaaactg atggcagact tcaagccaga
     7861 tacagtaatc gctcttggag gcggttctgc aatggacgca gctaagggaa tgtggatgtt
     7921 ctatgaacac ccagacacat ctttctttgg tgcaaaacaa aaattcttgg atatccgtaa
     7981 acggacatat aagatcgaca aaccagaaaa aacacaattc gtatgtatcc cgacaacatc
     8041 agggactggt tctgaagtaa cgccatttgc ggtcatcact gacagtgaaa cacatgtgaa
     8101 atatccgtta gcagattatg cattgacgcc agatgtcgca atcgtcgatc ctcaattcgt
     8161 catgtcagtt ccagcatctg tcacagcaga taccgggatg gatgtgttaa cacatgcaat
     8221 cgaatcctat gtttcagtca tggcttcaga ttatacacgt ggattgagcc tacaagcaat
     8281 caagttagtc tttgactatt tagaaaaatc agtaaaaaca cctgatatgg aatcacgtga
     8341 aaaaatgcac aacgcttcta caatggctgg tatggcgttt gctaacgcat tcctaggtat
     8401 ttgtcactca gtcgcacata aaatcggcgg ggaatacggg atccctcatg gacggacaaa
     8461 tgcgattctt ttaccgcata ttatccgcta taatgcaaaa gatccacaaa aacatgcgat
     8521 gttccctaaa tatgactatt tccgtgcaga tacagattac gcagatatcg caaaattctt
     8581 aggtctgaaa ggcgaaacaa cagaggaatt agtcgaagct ttagcaacgg ctgtttatga
     8641 attaggaaaa tctgtcggca tcaacatgag tctaaaagct caaggagtca cacaagaaac
     8701 actagataca accgtagacc gtatggctga attagcttac gaagaccaat gtacgacagc
     8761 taatccgaaa gaaccattga tctctgaatt gaaacagatc atcattgatg cttacaacgg
     8821 ataagcaaaa gaaagcgtag aaaaaagata agaaaataga tgaaaaagaa cttggaaaac
     8881 gttgtttctc caagttcttt ttttaatttc caagtaactg aaagttactt ttgttattta
     8941 acatttaggt caattttaga cagtttttgt tcaaaaagcg atatttatag tggacggtat
     9001 tactgctata ttaaggatat aaaatgaaag cgtttaaaaa ggtggcgtaa agatgattat
     9061 taaagaagag atttttgtac ctaaagaatt agtgaaagaa aaaattgacc tgctcgttga
     9121 aaacctgaca acgatcaaag acgataatgg tgaatttttg ttggactttg atggactgaa
     9181 agtagatgac aaaagctgga cagtgtggaa ttggccacaa ggtgtcggtc tatatggtat
     9241 ttataaaaat taccagatga caaaaaatcc tcgcgcttat caagtggtca atgaatggtt
     9301 tgaggatcgt atggaagaag gcgctccgcc caaaaacgtc aatacaatgg caccgctatt
     9361 gactatggct tacttgtatg aagacacgaa agattcacgc tatttgcctt atttagaaca
     9421 atgggcagaa tgggtcatga atgacatgcc tcggacaaat gaagacgggt tacagcatgc
     9481 cacatatgga ccggaaaata agaatcagtt gtgggacgat acattgatga tgacagtgct
     9541 tcctttggca aaaatcggga aactgttgaa tcgcccagaa tatttagaag aagctcgtta
     9601 ccagtttatg atccatatca aatacttgat ggataaacga acaggattgt ggtatcacgg
     9661 ctggacgttt gaaggaaatc ataactatgc cgaagcattt tgggctcgtg gaaactgctg
     9721 gttgacgatt gctattccag agatcattga aatcttagaa ttatcgaaag aagatgcatt
     9781 gcgcaaatta ttgatcgaaa cacttgaagc acaagtgcgt gcattaaaaa cttatcagtc
     9841 tgaaagcggt ttatggcata cgttgttgga tgatccttct tcttacgtag aatcttctgc
     9901 aactgcagga tttgcttacg gtattttgaa agcggtccat aaacgttatt taccacaaga
     9961 atataaagaa gtcgcttatc gtgctatcca aggattgctt gaacaaatcg atgaaaaagg
    10021 agaagttcaa aacgtttcaa tcgggacagg aatgggggac agtttagatt tttatcggaa
    10081 tatcggaatc acagcaatgc cttatggaca gtcgttaacg gtgctttgtt tgacagaatt
    10141 gctcgtctct tattgttaaa agaaaggaaa cccatatgaa aaaaacatca ctgctgtttg
    10201 cagcaagttc gcttagccta ggtctgctag gtctaagcgg ctgcggaaat aattctagtg
    10261 tggcaactgt cgcagatgca gatgtaaatg agatagttac cttgcgcttt gcttatgcaa
    10321 gcaacagcca gccagtaatt gatgcaatga atgaatttgg gcgtttagta aaagaaaaaa
    10381 cagatggttc cgtacagatc cagtatttcc cagatggaca actgggtgga gaacgtgaac
    10441 tgatcgaatt gacacagtca ggagcagtag atttcacaaa agtaagtgcc tcagcgttgg
    10501 aaagtttctc taaagattat tcgatttttt cagttcctta tctattcaat gatgaagaac
    10561 atttctttaa ggtgatggat aatgaagaaa taatggagcc aatctaccaa tcgaccaaaa
    10621 atttaggatt taccggattg acctattatg attctggtca gcgcagcttt tatatggtag
    10681 acggtccgat ccatacgccg gaagatttga agggaaagaa gatccgtgtg atgcaaagcg
    10741 aaaccgctat caaaatggta gagcttttag gcggttcgcc cgtacctatg ggaagtgatg
    10801 aagtgtacac gtctcttcaa tccaatttga tcaacggatc agaaaacaat gaatttgtct
    10861 tgtatacagc tggacatggt ggtgtggcta aatactattc ctatgatgag catacacgtg
    10921 tgccagatat catcatcatg aatgatgcca tcaaagaaca gctaactgat gagcaggaaa
    10981 aagccattga agaagcagcg aaagaatcaa cggtttttga aattgaagct tttgcaaaag
    11041 caattgaaga agaaaaagct ttagcacaag aagaacatgg agtccaattc aatgatgtag
    11101 ataatacacc gtttcgagag gcagttgccc cacttcatga tatattcaaa aacgatccta
    11161 cctacaaaga cctttatcaa aagatccaag agcaaggagc gtagctgtga tgaaaatgat
    11221 tttaaacaag gtattagaga tcctgggagc tgttttgctt gttgggatgg tcgctgttgt
    11281 tttatggcaa gtattttcca gaacggtttt aggaaatcca aatacggtca cggaagagct
    11341 tgttcgattc ggtcttgtct ggtttgccat gttgtcttcc gcgtatgttg tgggacaaaa
    11401 agcacattta gccgtaacgg ttttaagtga aaaattaact ggcaaaaaaa gtaaaatttt
    11461 agaagttgtt gttcaaagtt tatttctggt atttgctgcg atgatcatgg tgtatggcgg
    11521 atggaatgct gtcacattga caatggggca gatctcgcct tctttaagta ttcctatggg
    11581 atatgtttat ctgtcagtac ctgtatcggg ggtactcatc attatctata gcctgatcaa
    11641 tctaatcgat acattaagca acaagccagc aattcaagaa aaaatataaa aatggaggaa
    11701 taaaatggca atagaagccg gattagtgtt attttttgta tttgttgtgt tgcttgtatt
    11761 agggatgccg attgctataa gtattgcatt ctcatcgatg atgactttat tgttagttat
    11821 accgtttgat gtttctgctt ttagttcagc tcaaaaaatg gtgggaagta tcaatagttt
    11881 ttcgctgatc gctattccgt ttttcgttct ctcgggcatt atcatgaata atggagggat
    11941 agctaagaaa ctagtggatt ttgcgatgtt gttcgtcggg cgcgtgccgg gggctttggc
    12001 tcatacgaat gtgttaggga atgctttatt tggttccatc tctagctcgg ccattgccgc
    12061 ttctaccgcg attggcggag tgttgatccc tcagcaagtg gaagaaggat atgaccggaa
    12121 gtttgcgaca gcggtcaata tcgcgtcagc tccgacaggt atggtcattc ctccaagtac
    12181 tgcttttatc atgtattcac ttgttgctgg tggtgcttcg atctctgctt tgtttatggg
    12241 aggttatctc gtaggcgctt tgtgggcgct aggaatcatg ctagtagcat tcatcgttgc
    12301 taaaaagaat aaataccctg ttgtcgaaaa aggacagatg gctcatgctg gaaaaataat
    12361 aaaagaggcg attcctagcc ttctattgat tgtcatcatt atcggtggta tcttgacggg
    12421 gatatttaca gcagtagaag cttcagcgat agctgtcatt tactccctgt tgattgctat
    12481 gttttactat aaaacggtaa aactaaaaga tatacctaat atgttgtttc aatcagtagc
    12541 aatgtcaggg acgatcatgt tcttattggc tacttcttcc atgatgtctt tcgccatggc
    12601 gtttaccggt attcctcagg caattagttc gttgattatg ggcgtaacgg ataataaatt
    12661 tattattctg ttattagtca atcttgtgtt attactggtg ggtatgttta tggatgtggc
    12721 gcctgctatc ttgattttta caccaatatt tttaccaatc gtcacaagtg taggggttga
    12781 tcctgtacat tacgggttgt tttcaatcat gaatctgtgt gtaggctcca tcacgccgcc
    12841 agtaggtaca ggactatatg tcggtgcaag tgtaggaggc gtaaaagcag aggcaatgct
    12901 gaaaccgctt cttccttttt atggggttat cttagtcgtc ttgtttttga ttacttactt
    12961 cccgcaaatc gtcatgtggc tacccaatat gctgagttag gagaatagtt atgttgaaca
    13021 ttacaattag aggacatgat ctttccgaag tccaaacgat agaagatctt gcagaaaaaa
    13081 caaaagaaca agggattcat acactgcagc tcgccttagg tctttcgttt cctgaaatac
    13141 cttctggcgc aaatgagatc aattctggga tgggaaatta tgtcaaacga gttttagaaa
    13201 agcaagaagt gaccgtagga attttaagtt gctatatcaa tatgattcat ccagatttaa
    13261 cgatacgaca agagttgctg acaaagttcg agcagtatct tcgctatgct tcttcctttg
    13321 gtgcgtcgat ggttgcttcg gaaactggat gtgttttgcc ggaaatccaa tatacggaag
    13381 aaaatttcac agatgaagca tttgctgaag ctgtgtccgt tatccgtcgc ttggtaaaag
    13441 ctggagaaaa ataccaaatg atggtgggga tagaaccagg tttgaatcat ccggtgtatt
    13501 ctttagcaag ggtagagcag ctgatccaag cagtagattc ggactatcta ggaatcattt
    13561 tagatccgac caatttgatc acaagtagtg attatcaaga acaagtccaa ttggtagaag
    13621 aagcttttga acgttttggt gaaaagatat gtgcggttca tttgaaagat tttcgtgtcg
    13681 aacaggaaaa aatcgtgccg gtaaatttgg gagacggtgt gatcgagtac acaaaaatca
    13741 aagaaatcat catgaagaat cgtccgtacc tgtatgtggt tcttgaagaa acaaaagatg
    13801 atgggattcg ttatggaaga agtcttcttg aataatgtaa agaagacgtt ggttaactaa
    13861 tatttagaat ggagggggcg gggctagaag atgccacgtc tcttcttttt tataagagta
    13921 tataaaagca gctctttttg attacaaaaa acgtggtata ataaaattgt gcataagtga
    13981 acaaaaggag gtgcggcaca tgctccaaaa gaaaatcagc ggtgaacaag tcaatacgat
    14041 ggtttctgat cagtatgaaa tctatcatgt caaagatgtc gtcagccaaa ataaaacgat
    14101 ctatcatcat catgatttct atgagatcca tgctacatta aagggagaag cgacttttta
    14161 tttgaacgga cgacaattta cgatcaaagc aggaagtgtg ctgctcatcc attccaatga
    14221 tttgcatcgt atcgtccgcc aatcttcaga tgtattcgag cgtgtctata tctttgtcac
    14281 cccttctttt ctagaaagtc gttccacgcc atggtctaat ctatcggctt gttttcaacc
    14341 aatgggagag aagaggagtc gtgtattgca aatagaacag gaagtattga agcaaaaatt
    14401 atcatttatc gaccatcctc ctgataaaaa aatttacggt gaagacataa aatatgaaca
    14461 agctctggta gaatacttga tttttctcaa tcaagttgta caaaaagaag agagtgcgca
    14521 agaacagaat gctgtagttc ctaatgagcg tgtggaacaa atgttacaat atatctcaaa
    14581 aaatttatct catccgcttt ctttagagga aatggaaaag cagttttttg tcagcaaata
    14641 ccatatcaca cgagaattta aaaagtacac tggatttacg tttcatcagt atgtaatgaa
    14701 gaaaaagctg atctatgcca agcacttgtt gcgagaatac cgcagctcta gtgctgtata
    14761 tagtaaaagt ggtttttctt cttatccgca ttttctgaaa gcattcaaga gagagttcgg
    14821 cataacgcct aaagaatttt tgaaacgtga tacacagaaa cagttggttc attatgaaca
    14881 ttttgaagat gaacaatgag aatgatcact aaaaaataac cgcagtagct gctgttgttt
    14941 acatagaagc agaaactgcg gttattttat ttttatctat atatttcaaa atattttgaa
    15001 aaaatgacgt acatattata tgaatcagct gaatttacga aagtctctcg gcgatagtcc
    15061 tgtttttgct ttgaacaggc ggctaaagta agcaaaattc tcaatcccta tttcttcgga
    15121 aatcattcga accgtaaatt ctgtataccg aagaaggtct ttagcgtaag aaagtttttt
    15181 gctgatcaaa taatcgattg gtggagaacc gataaatttg gaaaaatctt tgctcagctg
    15241 atatttattc aataagaatt gttgttctaa ttgatcaagt gtaatcgttt ctttgaaatg
    15301 ttcgtctaag tattgcttca gtttgtaaac gtaggcggga atatcctctt cttcgaaatc
    15361 tagctgatac ttttgcaaaa tcagttcatt cagcaactcg tggatatcta cagaggactg
    15421 gaaatcggta cgggcattcg tgccttgttg catgtggatc aattctgtga tcaaatggtg
    15481 gatcttgttt tctgatggat ctcctgttga atggaaggtg ttatggccgt cttttgtgaa
    15541 ctcctgataa aatgattgga cgttctgacc attcaaatgg atccaatcca tttcccatgg
    15601 ttcttcgctg atcgtttgat aacgctgata ttcttggcag tcaataaaaa ataagtctcc
    15661 agcttttagc tgttgctgat tatcattata tgtaagcgaa cctttgccag acaaagtaaa
    15721 ctttatcaag taagaaggta aatgtgctcg ttcagtatag taagggattg gtgctttgaa
    15781 gtaaccgatt tcttggatat aaaaaaataa attcctgctt ctttgtgtag gcgtcaagat
    15841 cactcttttt gagtcttccg accatgagtg gttggctttt tcccagtaat ccatgtaaac
    15901 actcccaact tgtcaagata atgcaattat ataccaaaat agtgtgaagc aaaatataag
    15961 attctgtatt atgatagcat tgtcaataaa tgataacgct ttattaataa agtgctaatc
    16021 aacaataaag taaaagaggt ggagaaatga atccaacatt tgttgccatc gatatcggtg
    16081 catcaagcgg acgactaatg aaaagtacga gggatgcaaa aggttctttg atcttggaag
    16141 aagtacaccg gttcaaaaac ggctttcgga acaaagacgg tcacgatcgc tggaagatcg
    16201 attatcttat caaagagatt ttgattggat ttgaaaaatt aaagcagaca gggattgatc
    16261 gcctttttgc ggggatcgat acatgggcag tcgattactg tctgattgat gaacaagggg
    16321 atcggataaa tgatccgatt gcttatcggg acaagcgtac caatggagca gtagaacagt
    16381 tttctgaaat ctattctcta gataagttgt atgagcagac agggattcag atccagcctt
    16441 tcaatacctt gttccaattg tttgctgaag aaaaagaaaa tttggcaaaa gcacataaat
    16501 tgttactgat acctgattat ttagggtatg tctttactgg taacatggtg acggagaaaa
    16561 ctaatgcatc tactatgcag ctgctgaatg cagggacaaa agaatgggaa atagaacttc
    16621 ttgaaaaaat cggtgtctcg aaggaattat ttccaccatt gacagagccg ggaacgatac
    16681 taggagatct gcaaaaagaa caattttcaa aatatgattt gccagatgtg acctttatca
    16741 cagtagcaag tcatgatacg gcgtcagctg tattaggaac gccaggtcaa ggagaacgtt
    16801 ggggttatat cagcagtggg acatggtcgc ttttagggat tgaaacaaag atcgccaatg
    16861 tttctcgcaa tgctttttct gaaaattata cgaatgaatg gggtgcccat aacacggtgc
    16921 gttttttgaa aaacatcatg gggatgtggt tgatccagga agttgcccga atgcaagagt
    16981 acgagtacag ttatgcggaa ttggcagagc ttgctgcaaa agaaaaaccg ctgcagcaag
    17041 tgatggaaat caatgaccct cgatttttga atcccccaaa tatgatagaa gagattcagc
    17101 aatactgttt tgaaacagag cagccagtcc ctgtctcatc gggagctatc gctcgttgtg
    17161 tgtatgataa tcttgctctt tgttacgcac aagagctgat caaagtagaa cacttaactg
    17221 gaacgaaatt ggaaaagctg cacatcgtag ggggcggatc gaataatcgt ctactgaatc
    17281 aattgacagc agattatgcc ggaatcattg tagaagcagg acctagtgaa gccacagcaa
    17341 tcgggaatgt tgccatgcaa atgctcagta caggtcagtt ttcgaatata gaacaagcaa
    17401 gaaatgtaat caaacagtcg tttccatgtg aaacttttta cccagatgaa aataagcaaa
    17461 acacgatgga atggtacgtg aataaaatca aaggagtaat cgtatgaaca cgattgaaag
    17521 aaattacgaa caagcaaaag aaaaatatgc aactatcggt gtagatacag atgctgtact
    17581 agaaaagata caggacatca aaatttctat gcattgctgg caaggagatg atgtcaaagg
    17641 tttcttgaca ccggatggcg aattgaccgg tggaatcatg gcgacaggga attttccagg
    17701 agccgcacga acacctgaag agcttagaca agatctggag aaggcttatt cgttgatacc
    17761 gggcaaacac aaattgaacc ttcatgctat ctatttggat acagaagaat ctgtcgatct
    17821 aaatgaaatt gagccgaaac attttgaaaa atgggtagag tgggcaaaaa aagaagaaat
    17881 cggtcttgac ttcaatccga ctttcttttc gcatccaatg atgaaagacg gctttacatt
    17941 ggctcatcca gataaagaag ttcgtgaata ctggatcgaa cacgggaaaa gaagccgcaa
    18001 aatcgcggag tactttggga aagaaactgg gcaaacaagt atcaataact tttgggtacc
    18061 tgatgggatg aaagataatc cgattgatcg ttttacccca cgggaacgtt taatggaatc
    18121 actcgatgaa atttttacag aagagttaga tgaacggtat gtacaagatg cagtagaaag
    18181 caaactattt ggtttaggcg ctgaagctta tacagtcggt tcccatgaat tttatatggg
    18241 ttacgggttg actcgtgaca aacttgtttg tctagatgct ggacattttc atccaacaga
    18301 agtgatttcc aataaattat cttcattagc tttattcagc aaaggaatca tgttgcatgt
    18361 ttcccgtcca gtgcgttggg attcagacca tgtggttttg atggatgatg aattgcagga
    18421 aatcgctaaa gaattagtcc gtaacgaatt gttggaaaaa acaaatatcg gtctggattt
    18481 ctttgatgca acgatcaacc gtatcgctgc ttgggtcatc ggtacgagaa atacacaaaa
    18541 agcactgctg aaagctatgc tggaaccagt tgagcgattg aaagaaatgg agctggcttt
    18601 tgactttact tcaagaatgg cttatacgga agaattgaaa gatttcccgt atgccgatgt
    18661 atggaattat ttctgttaca aaaatcaagt tccagttggt ttggattggc tggaagaagt
    18721 ccaggaatat caaaaagacg tgttggaatt aagaaaatag gagtgtggct atattgaaaa
    18781 aaatagatat tttacaagcg ccttatgtga aagaaatgat cgaaacgacg tcgaatcttt
    18841 atcgcttggg atgggatgaa agaaatggcg ggaatatttc ttatttacta aaagaagaag
    18901 agatcacacc gttcttggat cctgaaaaag tgatccgccg catctcgatg atttttgatg
    18961 ccagccgttt agcaggatgc tattttattg taactggttc aggaagatat tttaaaaatg
    19021 tagcgagcga acctgccgag aatcttggaa tcgttcgagt tgctgaagat ggcaaaacac
    19081 tggaactttt gtgggggctg gaaaacgaat gccttcctac aagcgagttg ccaagtcatt
    19141 tcatgagtca tatcgcccgt ttagaagtag acccagataa tcggatcgtt atgcattgcc
    19201 atgctagtca tctattagcg atgagtttta cgcatgaatt agacgaacgt tcctttagtc
    19261 gtacgctatg gcaaatgtgt acggaatgct tagttgtttt tccagaagga atttccatca
    19321 ttccgtggat ggttccggga acaaatgaga ttggggaagc aacagctgaa aaaatgaaag
    19381 aaactcgatt ggttttatgg ccacaacatg gaatctacgg gtcaggaaaa gacatggatg
    19441 aagtctttgg tttgatcgag acagcagaaa aggcagcaga agtctatacg tacgtcaaag
    19501 cgcaaggacc aatcttgcaa acaatcacgg acgaaaacct gtggcattta gcagatgcgt
    19561 ttggtgtcac tccaaaagca ggttatttgg aggaagttca tacgaaagca ggtgtctgac
    19621 atggtgaaaa aagctttttg catgaaagtt tacccagaaa aacaagaaga atacaaaaaa
    19681 agacatgatg aactttggcc agaaatgcgt acagcacttc gtgaacacgg ggtcatcgac
    19741 tattcgatct atcttgatcc gagtacaagt ttgttatttg gttacttagt gatcgaagat
    19801 gaaaagttat gggaaaaaat ggcaaataca tctatcaatc aaaaatggtg gaagtacatg
    19861 gaagatatca tggagacaaa tccagatgcc tctccagtca gttgggaatt gatgccagtc
    19921 tttgaactgt agcaacaagc aactgggcaa ccggttgctt ggggttcttt cgtttttatt
    19981 gtgaaaaata atacaaatta ggaggaatag aaaatgagta atcgaatgat tttaaatgaa
    20041 acatcgtatt ttggaaaagg agcgattgag tcgatcgtcc ctgaatttca gcagcgagga
    20101 ttcggcaaag cagctgtcat tactgacaaa ggattgatcg agcacggtat agcaacaaaa
    20161 gtaacagaac ttctagataa agcagcaatc gcttatgctt tatacgacgg gatcgtacct
    20221 aatccaacga tccaaaatgt aaaagatgga gtggcttttg ttaaagaggc agaggcagac
    20281 tgtttgatcg caatcggtgg aggttcgcca atcgatacgg caaaagccat tgggattatt
    20341 ttgacgaatc cagagttttc agacgtcatt agtttagaag gtgttgctga tacgaaaaat
    20401 ccatgtttac ctatattagc tataccaacg acttctggaa cagcagcaga agtaacgatc
    20461 aactacgtca tcacagatga agtaaatcac cgaaaatttg tttgtgttga tcctcatgat
    20521 atcccaatcg tcgcgttcat cgacagcgat atgatgatgg gaatgccgaa aaaattggct
    20581 gcatcaacag gtatggatgc tatgacgcat gctattgaag ggtttatcac aaaaggcgct
    20641 tgggaaatga ctgatatgct gcatttaaaa gcaatcgaaa tcatcggcca ttctttggaa
    20701 gcttctgtag atggcgatca aaatgggcga gaaaaaatgg cattaggaca gtatattgcg
    20761 ggaatgggct tctcaaatgt cggtttagga ctggtacacg ggatggctca cccgttaagt
    20821 gcatggtaca acattcctca tggcgtagcg tgtgcagcac ttttgccaac tgtcatgaaa
    20881 tataacaaag aatatactgg agaaaagtac cgtgagatcg ctcttgttct agggattaaa
    20941 ggagcagctg aaatgtcttt agaagatgta agagaagcgg cttgtggtga gatcgatcgg
    21001 ttgagcaaag cggttggaat cccagaaacc atttctgaat taggtgtaaa agaagcagat
    21061 attccagcaa ttgcagaaga tgctttgcga gatgtatgca caccaggaaa tccaagagaa
    21121 acgacagtag aagaaatcat tgctttatat caaagtttga tgtaaaaacg aagcggatct
    21181 tcaacattaa attgcctgta aagagaaatg gtagtttata tctggatatc tcttttaaat
    21241 tgatggtatt tccgctataa tttttcttat aaagaaatag gagaatatta tatggaaaat
    21301 aaaaagcctt atggaactgt attgatcaaa gcctctaaaa tactagacta tttagcggaa
    21361 aaccaagatg tctctttgca gacgatcgca aagggtgtgg gaatgacctc ttctacagtc
    21421 ttgaaaatac tagatacttt gttgatgatc ggctacgtaa ataaaaattc agagaaaaac
    21481 tatcgtttag gtgcaaagct tattcgctac gcgaataaaa acattgaaca aatcgatttg
    21541 gtagagttga ctttaccgtt tttagaacag ctgcagcaaa agatcgatga gactatccac
    21601 ttaggggtat tggacaacaa tgagatcttg tacgtgaaca aactagatcc aaaacatcaa
    21661 acgatccgca tgtcttcaaa aatcggaatc acccgaccat tatacaattc tgcgatgggc
    21721 aaagccgtat tagcagaatt cagtgaagag cagtacactg attatcttga aaagcatccg
    21781 ttgatccctt acacagaata tacgatcacc aatgcattac ggttgaaaaa ggaaatcaaa
    21841 acggtaaaag aaacccacat cgcatttgac gatgaagaaa tcgaacgtga tattttttgt
    21901 ataggagcct caatcgtgaa aaacgaacaa atcattggtg catttagtgt aagtatgccg
    21961 aaatatcgtt taacagatga gacaaaagaa caaataatca gtgccctcaa gcaaacaaaa
    22021 agcgaaatcg agcaaagaat tcaaaaataa tgaaaaaagc gtttgcaatt tttcttttct
    22081 gccgtataat atgggtatag atttccaagt tataaaataa aatttctaaa taggaaatag
    22141 gtggagaaga tgaaaaaaat tgatatttta tctcgattga aaaacgccgg agtgattgcg
    22201 gtggtacgcg gaaaaagcaa agaagaagct ttgaatgctt gccacgcaat catcaaaggt
    22261 ggtctaactg gtattgagtt gacttttaca gtccctcaag cagatcaagt aatcaaagaa
    22321 cttttgtcat tctacaaaga ccaaccagaa atagtgattg gcgcaggcac agtattagac
    22381 gctgtcacag ctcgcttggc tatcttagct ggcgcagagt atattgttag cccttccttt
    22441 gatcaagaaa cggcagagat gtgcaatctg tatcaaattc cttacttacc aggatgtatg
    22501 actattaccg agatcaaaac agcgctgaaa agcggggtag atatcgtcaa actatttcct
    22561 ggaagcgctt atggaccaag tatcatttct gccttcaagg cgccgatgcc tcaagtcaat
    22621 atcatgccaa ctggcggtgt gagtctggac aatatgaaag agtggttcga tgctggtgtc
    22681 gtaacagtcg gagtaggtgg gaacctttta gcacccgcag ctacaggaga ttttgacaaa
    22741 gtaacggaag tcgcgcaaca gtatgcagca aaaatgaaag aaatcaagag gtagctgctt
    22801 atgggaaaag tagtgacact cggagaaatc atgttgcgat tgtccacaga gcagggaacc
    22861 cgtatcgatt caagtgaacg attcgctgcc cattatggcg gaggggaagc aaacgtagca
    22921 atttctttag ctaattacgg acatgaagcg atttttgcta caaaagtacc tgataacgca
    22981 ttgggaaaag cagtcaaaaa gcacttgcaa tgttatggag tagatacgaa acaggtatta
    23041 tctggtggat caagactagg tacttattat atggaaactg gtagtggcga acgcgccgcc
    23101 tcagtgatct atgatcgtgc cggatcaagt tttgctgaaa tggatcattt ggaatggtcg
    23161 ctagaggagt tattccaagg aatagatata tttcatgttt caggaatcac cccagctttg
    23221 tctaaaaaat ggcaaaaaat gacgaaacag gtgatagaag ctgcaaaaaa agctggctgc
    23281 ctgatcagct tcgatatcaa ctatcgtgga aaattatgga cacagcaaga agccagcgaa
    23341 gtaatccatc agcttttacc tttagtagat atctgctcag ctggaaaaat ggatgctctt
    23401 tatttgttag gtatcgagaa agcgccagaa gcagaagaac aacctctaat ttattattat
    23461 caaaaaatgc aggaaaagtt cccgaatatt caggtgtttt attcgaccaa gcgtaccgtt
    23521 cattcagcaa gtgaaaatga attgaagggg acattgtgga tgaaccatga atatgtggaa
    23581 tcccaagtcc atagaatcac cccaatcgtg gatcgagtag gtggcggaga tgcttttgca
    23641 ggtggcgtgc tccatgggat tttatccaat atgtctccgc aagaaatcat tgattttgct
    23701 acggcagctt ctgccttgaa gcatacgatc catggggact gcaaccaatt tagtcaagaa
    23761 gaagtcgcac aatttttagc atgcggctct ggaaaaatca ttcgatagaa ggagtagaag
    23821 aaaatgcaag aaatggaaac acgttataca cacagtccag aagatatccg tcattattca
    23881 acggaacaat tgagaaaaga atttttagta gaaaaggtat ttgaaccagg gaaaatcagt
    23941 ttgacttata cgcacaacga tcgaatgatc tttggtggag tgacacctac tgaaaaagaa
    24001 ttagaaatca cattagacaa agaactaggt gttgattact tcttagagcg tcgtgaacta
    24061 ggtgtgatca atatcggtgg accaggattc atcgagatcg atgggcaaaa agaagaaatg
    24121 aaaaaacaag acggatacta tatcggaaaa gaaacacgac atgttgtatt ttcttctcaa
    24181 gatgctgaaa acccagctaa attctatatt agttctgttc cagctcatca taaatatcca
    24241 aatgtaaaaa tcagtatcga ccaagtaaaa ccaatggaga ctggtgaagg cctgacactg
    24301 aatgaacgta aaatctacca atacatccat ccaaatgtat gcgaaagctg tcaattacaa
    24361 atgggttata cgattttaga accaggaagc gcttggaata cgatgccttg tcatacacat
    24421 gaacgtcgta tggaagctta tgtctacttt gattatgcca atgaagatac acgtgtgttc
    24481 cacatgatgg gcaaaccaga tgaaacaaaa catttagttg tagacaatga acaagccatt
    24541 atttcgccaa gctggtcgat ccattcaggt gtaggtacaa gcaattactc attcatctgg
    24601 gcaatgtgcg gagaaaatat cacctataca gacatggata tggtgcaaat ggatcaatta
    24661 aaataagcat aagggagaga aaatgatgga atttagtatg gatatgtttc gtttagatgg
    24721 aaaagtagca ttagtcaccg gtgctgtcta tggtattgga tttgagattg cacgctcttt
    24781 agctacagca ggagcaaaaa tcgtatttaa taacttgaat caagaatcag ttgatgaagg
    24841 tatagcgcat tataaagaag caggcatcga tgcaaaaggt tatgtctgcg atgtgaccga
    24901 tgaagaagcg gttcaagcga tggttcaaca gatcaaagaa gatgtaggtt cagttgatat
    24961 tctagtcaac aatgcaggga tcatcaaacg gacaccgatg atcgaaatgg atgcggcaga
    25021 cttccgccaa gtaatcgacg tggatttaaa tgccccattc atcgtttcaa aagcagttat
    25081 tccggatatg atcgaaaaag gcggcggtaa aatcatcaat atctgctcca tgatgagtga
    25141 attaggacgc gaaacggtca gtgcttatgc tgcggcaaaa ggcggattaa aaatgctgac
    25201 gaaaaacatc gcttctgaat acggtcaata caatatccaa tgtaatggaa ttggaccagg
    25261 ttatattgct acaccgcaaa ctgctccatt acgcgaaaca caagaaaacg gtgaacgtca
    25321 tccattcgat caatttatcg ttggacgtac gccagcagca cgctggggcg agccaatcga
    25381 tttggctgga ccatctgtct tcttggcttc tagcgcatct gatttcgtta acggccatgt
    25441 cttgtatgtg gacggaggca tacttgccta tatcggaaaa caaccttaaa agagctttag
    25501 tacactgttt agtggagagg ttgtgaaatc agcggattga acgaataccg aaggacagct
    25561 gattaaacat catttattcg aaaaaagagg ctgggacaga agcatttaac tccaagaaat
    25621 aagaaggaat tcacgaaaat tgcttttcaa gtttttgtga atttcagctt atttccgaag
    25681 gagttgcttt tacttccgcc gtttgtacgt gtttagagcg tgagacaaaa gtgttcttta
    25741 cttttgtccc acgctctttt ctgtgcgtct tccatacttc actaagtcga tccctcttgc
    25801 ttcgcaccaa tccttcactg gtccggaaaa gatcagagat tgttggtgta gggccgcggt
    25861 attcgttgcg ccgaccatag tataaagcag acgaagctct tcttgccatt gcttcatcag
    25921 tataatagtt tcttctacgc cgtgattcat cagatgcgtc agtacggttc ctgaagtacc
    25981 cacggcattt gcgccgagac aaagggcttt aaatatgtca taggcattgc ggatacctcc
    26041 ggaggctagg atttccatag aagtgtctgc ttcatttgct tcaagcaatg aagagactgt
    26101 cgattgcccc cagtcagcta aataactcag ttcccgcttg gagcgacggg cgttttcgat
    26161 ctgggtgaag cttgttccgc ttcgaccgct gatatcaact gtatgaactc ctaaagcagc
    26221 tagatcattg agcgtttctc ttgtcatgcc aaaaccgact tcttttacga tgagggggac
    26281 gtcaatggct gtttgagttt cttgaataag tactttccaa ttggtaaaat cacggtctcc
    26341 ctcaggcata accaactctt gaggtgcatt caaatgaatc tgtaaggcat ctgcgtgaaa
    26401 caatcggata gcttctttgg ctctttcgac agaagtccct gcaccgatgt tggcaatgat
    26461 tttcccgtga ggatattctt gtcgcataat cgtataagta tcggctaaag aagggacttt
    26521 caaggcagcg ctgactgaac cagtggcaat catcaaatct gcttctcttg cgacgattgc
    26581 aagatcttgg ttgatttttt ttgttttttc gcttccgcca gtcatcgcat tgatataaaa
    26641 tgggctgctt agtgtaaacc caactgcctg tgtacttaga tcgacatcag aaactgctat
    26701 ttgcggcaaa gggttatgga tgatccgtac gaagtcaaat tcgttttttt gtttatcatg
    26761 aaaggcttta gctagtgaaa catgttcgtc ttttcgattc atcggttttc ctttctttga
    26821 tcgctataga catgtaacgg cagtggagtg atttctgctt tttcccatgc actcattaaa
    26881 ggaagaatgc cagatttctg gtcaacaatt acgattccgc aatcgccccc acctgcacca
    26941 gaagattttg cggctccttc atactgttca gctaaattac acaatttgtt caaagcaggc
    27001 gtttcgatga cgaccccagt gattgcagat aaatcatgca gtaattgtcg gttttttcga
    27061 atcatctgtt ggatcaacgt tacattattt tctttaaacc ctttgatcat ttcgttgaca
    27121 cattctgtac tattttttaa gaaaagctga taagccacca ttttatcttc tctcgaacgg
    27181 tgaacttgat cgaccaaatc agaagtagag gcagggctac ccgtccaacc aatcaataaa
    27241 cgtaaatctt caggagcaat caatggctca atggatagac ctggccaatc cagggcaagt
    27301 aactcactga tagaatgctg agtttcttgt tcttggagcc aaggatggtc gaaggttgag
    27361 aaagcgatcc agccaccata acagctagca gcgatgtcgc cgcaggaacc attatcttga
    27421 actgctaaat tggctagtgc tgcaatcttg aaaatctcca actgagataa attcaacgcg
    27481 taaaaaacat tcaaggcttt gaccgttgca acggtcacgg caccgctaga acccaatcca
    27541 tatttccggc catttgaact gtctaactca cttgttactt tcagatcata aaaggataaa
    27601 agaatgtttt tttcttgtgc atacttttca gtcaagcgaa tagcagcaag gatataatga
    27661 aaaggatttt cccgaatatc taaaactaat tctccgttgc gtcttgtcca acgtacaggc
    27721 atcccactat attgtgcaga ttggatactt ccgacttttc gtgcagattc tacagtgact
    27781 gtcacgaatt gatcgactgc agcgataact gctggatggc ctgtttcaac aactgcatat
    27841 tctccggcaa tatagagttt gcctggtgca gatacttcaa tcataaaaat ctccctttat
    27901 tcaataatcg caattcctgg accagcatgt gcagtaatta cttgttcttt gctaaataat
    27961 ttggtaaatg tttcttgtac ctcagataaa tggctgtttt ccactaaaac tttgaaatta
    28021 gggccagcat ccatcgtaaa gtagcatgga atgccttgct ttctcaattg tcgcaccgca
    28081 tccatcgctt ttaagctgtc aggagaccag taagtgaatg gaggctgggc agctaaagtc
    28141 gttccatgca tttttagtcc gtttctttcc atcgtttctc cgagaagttg gaaatctttt
    28201 gttttgattg cttgtttcaa ttgatataga tccccttcaa cggaatctaa ccagccttga
    28261 taaaaactgg atgtttcgac tgtccgacgc atcccatttc tgctggacac ttcttttttc
    28321 tggtcgttga tcaaaacgaa aaccattgct aaatcgtctt cgaaagaatc ggaagggact
    28381 ggcttagcgt aagaacttaa gtcgtcatgg cctttttccc attcgacgaa accaccgaaa
    28441 atacttcggc aagctgaacc agacccgcgt cgagcaaatc ttgaaagaga gagatcatct
    28501 aatccaagct taagagcagt attgcaagcg cctgctaaag cagctagccc gctggcagag
    28561 gaggctaatc cagctgcggt aggaacgaaa ttctgactga ttactgaagc ttttagtgag
    28621 aggccggctt ctttacgaaa aaggtcaaga aactgactga ctttttttgt tgctttttcg
    28681 tcttgcaagg tgccatctag ataaaattca tctaccatat agctatcaga aaagatgact
    28741 tctgtctctg tataaaatgc atccaatgtt aacgaaaggc tgttgttcat tggaaggatg
    28801 agttcttcat ttttcttacc ccaatatttg attagagcaa tgttggtata tgcgcgtgct
    28861 ttgcctttaa acataggtat gtactcctaa tccttgtatc caagtttcag cagcacccgc
    28921 atcttcaagt gcttgactga tttcttgggc ttttgttttt gtttgtgcta atgcaatcat
    28981 acagccaccg cgtccaccgc cagttaattt ggcacccaat gccccggtat cttttgctgt
    29041 ttggatcaat agattaagaa aatcattgct gattgtcagc ttttccagaa gtgattgtga
    29101 ttcatccatt gtctgtgcca acgtttctgg tgaattttca atgattgctt gttttgcttg
    29161 cttcgtcaag tatcctaatt tttggatcat ttgtccagtt tcatgaggct gggtttcaaa
    29221 gaggtgagcg acatctttga cggcttctct tgtttgtcct ttgattcctg tatcagcgac
    29281 aatcaaaaaa gcatcgatgt tcaaagaaaa gtagtcgaaa ggatgccctt ttgtaaaata
    29341 aatcggctgc aagctgctag tagcggctgc atcgattcca ctaggattac catgggcgat
    29401 tttttccgaa agctggacat tttctaatag tatttcacga gacaaaggaa atgctaagta
    29461 atcataaaaa gcacgagtga ctgctgtggc gactgcagcg cttgatccca ttccacgttc
    29521 agcaggaatc gtgctttcaa tggtcagttg caagtttttt tggatgtcat gctgtttttt
    29581 taagtgaatg aataattttt tgatattttt taatgcatga ggagcttcgg ctaaatttcc
    29641 tgaatagtag gaagaaacca gttgatcgtc cattgcatcc agctcttcaa ggaatgcggt
    29701 gacttttgtt gcatagaaag gaaaggcaat cgctggttct ccataaacaa ccgcgtgctc
    29761 gcccatcaat atgatctttc cgcttgattc tccttggcca tagtttgcca taatctaact
    29821 ccttctcacg taaaagtgat ttttaagcaa aaaataaagc gcccaaaacg agttgcgctg
    29881 cttcacgaat ttttttgtcc actaagggtc tcaaaaaaca ttcctccttt attttactaa
    29941 aaccatctca gaagtaaaac taagaatacg ttttctaaag aaaaaacact tttttcttaa
    30001 gaattttttg actttttttc ttctttgact agaaaaaaat acaattgaca ctactagata
    30061 ttgggggtat atttaaaaag gttggagtta aacacaatat ttagtgatga agtgagctgg
    30121 aggtaaatga gcgtgatcgt tttagcaggt acaattggtg ccggaaaatc aagtttaaca
    30181 gaaatgatgg ctgaacactt tgatagtcag gcattttatg aatcgattga tgataatgaa
    30241 gtcttgccct tattttatgc aaaccctgaa cagtatgctt ttttgctgca aatttatttt
    30301 ttgaataaac gttttgcaag catcaaacaa gcaatgaaag atgacaataa tgtattggac
    30361 cgttcgattt atgaagattc actgcttttc catctaaatg cagatctagg aagagcaaca
    30421 gaaacagaag ttcgtgtgta tgatgaactg ctggaaaaca tgatggaaga acttccctat
    30481 gctgcccata aaaaacatcc ggatttatta gttcatattc gtgtatcttt tgatacgatg
    30541 ttggagcgta tcgaaaaacg tggtcgttcg tatgaacaat tgtcctttga tccaagtcta
    30601 tacgattatt acaaagaatt gaacagacgt tacgatcaat ggtatgaaga atacaaagaa
    30661 agtccaaaaa tccaaatcga tggagaccgc tataattttg tggaagatcc tcaagcaaaa
    30721 gaagaagtct tgaaaatgat cgaagaaaaa ttagcagaga ttcgccaaac caaagtagcc
    30781 atttgattta cagttgctca aataaagggt aaacctttat ttgagcgact tttttcttta
    30841 tactggaaac aaatgtcagg aggatagagt atgcgggaaa aacactattt taatcaagac
    30901 cgtaattttt ggatcaatgt acagcaaaac gatgtgctag ctgttaaaaa cttaaaagaa
    30961 gaatatggca ttagtgacga gatgctgact tattctctag ataaaaatga acgggcgcgc
    31021 gtagagtacg attcttttga tgaagcgtta ctgcttgtat caaatgttcc gcaccagcaa
    31081 aaagtcgata atcattatga aactagtcct atcgctttta ttttaaaaga agacggtttg
    31141 tttacattta ccacgccgaa taccgagtac gtgattcgac taattcgatc gcttttggaa
    31201 cgaatgccag acatgagtgt atacagttta ttgtttcgta cattgttttt gatttctgat
    31261 tccttttttc ctttaatcga ggaagtgaat agtgaacgtc agcggcttaa tctgaaatta
    31321 agagaaaaaa caacgaacaa gaatctgctg caactttcag atttagagat cggtttggtt
    31381 tacttagtta caggaacaaa acaaaatgta gtacttttag aacaaatcaa ggcattggct
    31441 atttatcgca agttgtcaga aaaggaaaaa gaagagttgg acgatgcgct gatcgaagca
    31501 cgacaagcag ttgaaatgac gaacttagct tcgcagattt tagaccagct ctctggcact
    31561 tataataatt tgctgaataa caacttgaat gacacgatga aatttttgac ggtctggtcg
    31621 ctgatcttga ccgttccaac tattgtgaca ggattcttcg gaatgaatct ccagttaccc
    31681 tttacccatt ccgttttcgg atggggaatc gccttgatca tcagtttggt cttatctatt
    31741 tggatgctta ttgcactgtg gcggcggatt cgttgatcta gtctttgatc tgcaaaccaa
    31801 gggcttgggc gatcacaagt gcttgctctt ggttgacgat tagtcccgcc aaagaatctt
    31861 gagataaagc gattgctgtg aagaaattag tcgtaaagtc taatcccttc agagaagttc
    31921 gaaaccagtt cgaaccggtc aactgattgt cagacaaaaa aaggtttttc caagtgacct
    31981 cataaaattc gctgtcttct aattgacaat gatcgaagga gacagctttc aagtttgtac
    32041 tactaaagga agccatcgaa gcaatacaat cagtgaaagt acagtctcga agataacttt
    32101 cggcaaaatt cgtacctgtt aatttacatt gatgaaacac gacttggtgg aaactgccac
    32161 caatccactc cagattggaa aaatcacatt tttcaaaaat gacattactg cattcaaaat
    32221 gacgtaaaac tgttttttgc atcgtaagtt tttggatatg actctctctt aataccatat
    32281 ttttggcatc gagatagctt tggtcacccc cgttgatcag aagaccagag aagatctcct
    32341 catcttctaa ataaaactct ccctttgtaa gaagaggaag agaaggtgga ataggttcga
    32401 tttttttcat gtgggttcac ctcgtttttc tttagtatag caaagaagcg ggaatcactg
    32461 ctagaaagtc tgctaatcta atcattttca gaaaaggaag acaaactgta tgaaaaacat
    32521 tgacaaaaag attagttttt gctatactat gatggttgag aaataaaagc agaagcaccc
    32581 gcttctcgcc ttagttgata atgtcactgg gctagatagt tttcactggt tctattaggt
    32641 gaagtacgcg cgggttctgt aagagaactc gtttttttat tgccgtttat tcggtaagct
    32701 tttctttctc tcataatatt tggaggtgaa tgaccatagc aaaggatatg atggttaacg
    32761 acggcattcg tgcacgagag ttacgattga tcggttcaga tggtgagcaa ttaggagtta
    32821 agacaaaagc agaagcattg aatattgcag aacaagcaaa cttggatctt gtgttagttg
    32881 cccctggtgc gaaaccacca gttgcgcgaa tcatggacta cggtaaatac cgtttcgaac
    32941 aacaaaagaa agaccgcgaa gcgcgtaaaa aacaaaaagt gatcaatgta aaagaagttc
    33001 gcttaagtcc tacgatcgac ttgaatgact tcaatacaaa acttcgtaat gcacgtaagt
    33061 tcttggaaaa gggcgataaa gtgaaagctt ctatccgttt caaaggccgt gccattaccc
    33121 ataaagaaat tggtcaaaaa gtcttgaatc gcttagctga agaaactgcg gatattgcaa
    33181 cagtggaaca aaaagcgaaa atggacggac gcagcatgtt cttgacgctg gcaccgaaaa
    33241 acgacagtaa gtaatttgaa tgactaactg gctgttggac agccgatagt cggataacga
    33301 aagattttga ggaggaaata tagtcatgcc aaaacaaaaa acacaccgcg gatcagcaaa
    33361 acgtttcaaa cgtactggta aaggcggatt gaaacgcttc cgcgcgttta caagtcaccg
    33421 tttccacggc aaaacaaaaa aacaacgccg tcaattgcgt aaagcaagca tggtttctag
    33481 tggcgacttc aaacgtattc gccaacaact agcaaaaatg aaataagaag tacaaataac
    33541 agaatctgaa gatttatttt tattaggagg aattatacat ggcacgtgtt aaaggtggaa
    33601 cagtaactcg taaacgtcgt aaaagagtgc taaaattagc aaaaggttac tacggttcaa
    33661 aacacacttt atttaaaaca gcaaaagaac aagtaatgaa ttcatacaac tacgcatatc
    33721 gcgatcgtcg tcaaaagaaa cgcgacttcc gtaaattgtg gattgctcgt atcaacgcag
    33781 cagctcgtat gaatggcttg agctactcaa aattaatgca cggtttgaaa gttgctgaaa
    33841 tcgacatcaa ccgtaaaatg ttagctgact tggctgttaa cgatgcagca gcatttactg
    33901 cattggctga ccaagcaaaa gaagctttgg ctaaataagc taaacaatta taaagaggaa
    33961 agaagataac gaaaagttat gttctttcct ctttttttat ttacaatcct ccatcaaatg
    34021 aaacaggaca ataacgtata agtctaaaat agcataatta aggtttttta attgaaaact
    34081 gaacatttat ggtcaccctt taatgaaagc gctaactaca taagttagaa tgagtttgac
    34141 tgatatatta gtttgcttat cagaaaaaca aaatggacgg aggaataaca tgagtgatat
    34201 tattattggt attttgttag ttatctcatt ctttttcatg gtctggtact gtgtaaaagg
    34261 ctacaacttg atggtcggct ttgccatcat ggctactgta tggatgggat tagcgctagt
    34321 cggaaacacg ttttcaccaa acccggcgat ggaagggcaa ggagtaattg atgtgttgac
    34381 gcatatctat acgacggggc cagctgagta cgccaaatcg atcttggtaa atgtcttctt
    34441 tggtgccttt ttcgggcgtg ttctagtaga tagcggaatc gcagctaccc tgattcgaaa
    34501 ggtagttgaa cttggagggg acaagccaag aatcacgatg agcttactat gtattgtaac
    34561 cgctgttata ttcatgtcga tgacaggaat cggaccagtg atttctattg cagttattgt
    34621 gttgccaatc ttgatgtcat taggtatttc agtaccggtt gcactgttct catttatggg
    34681 ctcgattatg gctggaatct ttgctaatat cgtcaatttc aaacaatatc aaacgattta
    34741 tgctggtttc aatccagcgg ctgaaagcta tacttataat gactatttcc aaattggtat
    34801 gattgggatg attgtaagct tagttgtggt actaacggtc gctaatatat caatgaacaa
    34861 aaagaaacgc tatgcaatgg cagcaaacgt accagctgaa ggtggcgacg caccaatgat
    34921 ctcatggtta gccgtattat taccagtttt aggggtcgtt cttttagatc ttccaatcat
    34981 cttaggtttt attctagcag gtatctgggc attgctgttt actggaaaat tgcgcggagg
    35041 ttataaagaa atctgtcgtc agtttgcgaa attatttaca gatggcgcag tagatgttgc
    35101 gccaatggtt ggtttcttga tgaccttagc gatgttcaat aattcagctg cgtatgcttc
    35161 tccttatttt tcagctattt ttggagattg gataccgcaa tcaccattag tcttggcaat
    35221 cgtatttgct atattgacac cactaggatt tttccgcggt ccaatgaatc tagtcggttc
    35281 aggctcagct attttagctg tcgtattagc tgttaatcca acgatgtcgc cagccttttt
    35341 gttcccgtta tttgcaatca caacgattgc tcctcagcat ttagatatta cacaatcttg
    35401 ggttgcttgg ggattaggtt atacaaaagt aacttctcga gaatatatga agaaatccat
    35461 cccaactggt tggatcatcg gagcgatctt atgcctgatc acgttcttat tgtacgggaa
    35521 cgcctagtaa acaaaacgtc gataaaaacg attagatgaa tggaggaaaa gaaaatgaaa
    35581 cgttttgtgc gaatgggaat tgatgttggc ggtacacata cgaaagcagt cgcaatcgat
    35641 aatgcgacgc acgaaatcat cggaaaatct tcagtgaaaa caacccacga tgatgtccgt
    35701 ggagtagccg caggtgtcgt tcagtctttt caaaattgtt tgctggaaaa taatatcagt
    35761 ccagaagatg ttgtgtttgt tgcacattct accacacaag cgactaatgc actgattgaa
    35821 ggagacgtag caaaagtcgg cgtaatcggg atggcaaaag gtggattaga aggtttttta
    35881 gcaaaacgac aaactagatt gaacgatatc gatttaggga ataagaaaaa aatagagatt
    35941 gtcaatgcat tcttacctgt caaacactta aatgtagacc gtgtttcaga aacgatttct
    36001 tctttagaaa gagaaagagc ggaggtcttg gtttcttcta tggcatttgg agtagataat
    36061 ggggaaccag aacgagttgt ttatgaagca gcatcggtaa aatcgatccc tacaacgatg
    36121 gcttctgaca tcacaaaatt atatggattg acaagaagaa ctcggacagc agcaatcaat
    36181 gcatctattt taccaaaaat gctagatacg gcaacctcta cagaagattc cgtacgagaa
    36241 gcaggggtca atgtttcttt gatgattatg cgcggagacg gcggagtaat ggaaatcaat
    36301 gaaatgaaaa aacgacctgt tttaaccatg ctttccggtc cagcagcatc agtcatgggc
    36361 tctttgatgt acttgagagc gtctaatggt gtttattttg aagtaggcgg aacaacaacc
    36421 aatatcgggg tcattaaaaa tggacgtcca gcaatcgatt attcaattgt aggtggccac
    36481 ccaacatata tctcttcatt agatgttcgg gttctaggtg tggcaggcgg ttcgatggta
    36541 cgggctaatc agtcaggaat catcgatgtc ggtccacgtt ctgcacatat tgccggtcta
    36601 gattatgcag tatttacgga gacagaaaaa atcaaaggtc ctaaggttga atttttctct
    36661 cctaaagaag gagaccctgc tgattacgtc aaggtagtga tggaagacgg agaagaagtg
    36721 actattacaa atacatgtgc agccaatgtc cttggattag tgcaagaaga acatttttct
    36781 tatggaaatg tcccatctgc acgaaaagcc atccaagcat tagctgatta ttgtcatacg
    36841 acggttgaag acatcgcaga acagatcatg gaaaaatcct atgctaagat tgaaccggtg
    36901 attttagaat tggcagacaa gtatcacttg gagaaagatc agatttctct tgtaggtgta
    36961 gggggcggcg ctgcctcatt gattacttac tttagtaata aaatgggtgt gaaatattcg
    37021 attcctgaaa acgccgaagt gatttcttct attggtgtag cacttgcaat ggtccgagat
    37081 gttgtagaac gtatcatccc ttcgccaagt aaagaagata tacgatcgtt gaaaaatgaa
    37141 gcgatgaata aagcgattga atcaggcgct acaccagaat cgatcgaagt ccacgtagaa
    37201 atcgatccac agacttcaaa agtaacggct atcgctactg gttctacgga agtgaaagca
    37261 accgatctaa ccaaggagat cacaacagaa gaagcactag agcttgctgc agaggatatg
    37321 cgattaaata aaaatgaagt ttgcttattg gaaaatacac ctttctttta tgtatgcggc
    37381 gaacagaatc gttcaaaaaa tgctggaagt cttcggatca tcgatcaaaa aggatttatc
    37441 aaggtccaac gtggacatgc ttcatgtatg aaaacaactg cagccaatta tatgacagct
    37501 gtcgaacaac tttgggaaga tatggcagtt tatcaaactg aattgattgc ccgaccagaa
    37561 ttttatctct gcttaggagc aagagtctct gattttacag cgacggatct ggaacaacta
    37621 cagcttttga tggatctgga agtatctact atggaaccgg aggaagaagt gatcgtcgtt
    37681 gccggaaata tcaaacaaac ataagttaga agagttacta aacgaattac aacagatccc
    37741 cgaagaaatt tggggattct accagtttcg gcgagattta ttttggaaaa agattccttt
    37801 gtccaagcag aaaattctta tacaacaatc aatcgattgt ggtatcgaaa cggcatgtag
    37861 catcaaaaaa aagtaccctt ttgccgatgt aggagaaatt tgtgaacaaa tggctgttcc
    37921 aatcgtttcc tgtgaatcag agcaaataaa cgaacgaatc acttttgcaa cttatgcaga
    37981 agatgaaggg attcgattga tgacggagcc gttagaaaaa ttaaaatgtt caggactagc
    38041 ttcgatctct aaagaaacag cgcaagcttt gattattgga catgaactat ttcaccacat
    38101 cgaagcttct gttaagggaa tttatacgca aagcgaaaaa attgtgctgt ggcggttgcc
    38161 tttttataca catcaatcaa acattcgtgc attgagcgag atagcagcga tgagtttttc
    38221 aaaagagatg aatcaaagcg atttttcgcc ttatgtatta gaggcagtct tactttggcc
    38281 atataatgaa attcgtagcc aagggatctt agaagaaata aaaaaaatag aaaaaagatg
    38341 tacggagtat gatttagatt acaaataaag agactgtgac aaaagtcgtg tcacagtcct
    38401 ttttttccga ataaacgatg ttctcctgtc aactcctcgg tcacaagtca aaatattcaa
    38461 caaacatgag aagctgtttt ttgaaattgt tccttgtgac tcggagatga acggcaggct
    38521 cacgacctct tggaaaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaag
    38581 ttaaaaacat aagaagctat ttttacttgg ctgttcttat tacttgatgc agggcagctt
    38641 tttcacaacc tctcaataaa cggtgtgcaa tcagctgacc ctcggtatta gctcaaaaaa
    38701 aacggcaaaa tatgaggaac tattttgccg tttctttctc taatactcag gtcaaaacgc
    38761 tgattccaaa acctcttatt tgatgggtct gtcctgaata tcttcaaaat aatcggggta
    38821 attatgaatc acgtattctt gctcctcgat aatcatatgt aaatgcatcg tgcaaagaaa
    38881 tccgacttca tcaaagttat gatcaatcat tgattgaagc attgtctgat gttcatctaa
    38941 tactcgaccc cagtctaatt ctgaaatcgt caaacgtaac catctgaaac ggttcaagtg
    39001 cgtactataa ctttctagcc aatcccaaat ttctcgtttt ccagcaattt cataacaagt
    39061 tcggtgaaaa tcagtatcca aatcaaaaaa agctttttta ttttgagcga ttactgcctg
    39121 atcggtttgt tctagtattt tttctagttt agcttgatct tgcttggtca ttttcgcact
    39181 gcattcttgc aggatcggtt tttccaactt ttcccgcgta taacgggcta atgaagcaga
    39241 tcggatatcg atttttgaaa cataagtgcc ggactgtgga atggttttta caagctcttg
    39301 attgcgcagt tggatcagtg cttctcgaat cggtgtacgc ccgatagcta gttgttcttc
    39361 taacacttta tcggagattt tacttccagg tgctaactcg gaataaatga tttgtttacg
    39421 tatagattca taagcttgct gttgcaaatt attgataacc atttaacctt cctttctatg
    39481 cagatataat ctattataac ataaatcgct tacaaatcgt gtgggcataa aaacacagtc
    39541 tgcaaaaaaa gccctgatag gcatgcctat tagagcctcg aaaagaaaaa tattgaatca
    39601 atctggtcgt acctcttgga tcggtttgac acgaccgccg attcttttag caaaagcttc
    39661 ggattctttt ttgtctttga aaatgagcag attgtctaag tttttttccc gagtgcgaca
    39721 gccagtttta tcgatgtaac cgtgcattac tttaacgaca tacatgggga tcacctgctt
    39781 ttttcttttc attatacgaa ctactcgaca caatacaaga aaaatgctta gacggtcttt
    39841 attaagaatt tacatcatcc aaagaagcgt acgcttggaa taactgatct aactccggat
    39901 tgactttgct cagcttcact aatcgttgcg aatcagaaag taaaaaacag tgtttactac
    39961 tgccagtagt ttttaatttt ttgtcttcag ttcccacaat ttcgtagcta aaatccaacc
    40021 gtgtccccgt atacttttgg atagttggat ggatgctcac tttttctccg taatggatca
    40081 tttctttata gctgcaattt acttccagaa cggggatgat gatcccagat tcttcgattt
    40141 ttttataggg aaaccctaga tgtaccaata aggctacccg agcctcttca aaccagcgga
    40201 tataattgct gtgatgaata atccccattt gatctgtttc ataataaaaa ggttctcgca
    40261 cataacctgt aaatttctcc atgactcatg cctcgttttc cattgatttt ttacaaaaat
    40321 aattcatcca tttcggaagt gcttcgctga tttgtgtcgg caaaacaata tattgttctt
    40381 ttgccagctg gtctccaatg aaactatgaa gataaatagc tgctgcaatc gtttggtcat
    40441 tttgaggaaa ctgggctaaa aatcctgtga tcatcccagc taaagtgtca cccatgccgc
    40501 ccgttgccat agcagcagaa cctaaaggat tggtgtagaa gtgctggtga ccataaattt
    40561 ttgtctcatg acttttcaaa acgagcacag caccgatttc ctgttgcttc tttttgtttt
    40621 ctttatcccg ttgttcttgt atcggtagag aactcaaccg ttgccactcc atttgatgag
    40681 gtgtaagtac agtttgttcg ggatagggta gcaaaagatg attagcagca agtaaactta
    40741 aagcagagcc atcaatcacc agccattgtt cttttgattg gttttctagt acttgtttga
    40801 aacgttccaa actcttagaa gaagtaccca atccgggacc aatcaagagt acatctgctt
    40861 gctttattac ggaaagaaac tggtcagtat ccgtccaaac tacaatcatt gcttctggca
    40921 gatgactgtg aagagcactc cgattttttt catcagttac tacagtcgtg agacccgctc
    40981 cgctgtgtac ggcagctaaa gcactcataa tgattgctcc gccatattgt tcattgccgc
    41041 caatcaaaac gatacgtcca aatgttcctt tatgtgaaat ttttggacga ggtgtgatga
    41101 ctcttttcac tagttgttcg tttatcagca tctaaaaacc tccttttact cattatagcg
    41161 tatatttttt ttagagaaaa acagataaga aaaggaattg tcagattttt tgaactattt
    41221 ttttctgtaa tttgtggtat catgaacacg aagacttaaa taagtggagg attaacttta
    41281 tgacaattga ttggcaaaaa gaagtagaag cacgtaaaga agacttgctt gaagacttga
    41341 aaaatctttt acgtgtcaac agcgagcgcg atgactcaaa agtaacacca gatgcaccat
    41401 ttggacctgg acctcgcgac gcattgaaac atatgttagc ttatggcgaa cgtgatggat
    41461 ttaaagtaaa aaatgtcgat aactatgcag ggcatattga tcttggcgaa ggagacgaaa
    41521 cgctagggat atttggacac atggatgtcg ttcctgcagg agatggctgg gacacagatc
    41581 cttatgaacc agtaatcaag gatggaaaga tctttgcacg cggatcaagc gatgacaaag
    41641 gtccaagtat ggcagcttac tatgcgatga agatcattaa agaacttgac ttgaaactat
    41701 caaaaaaagt tcgcttcgta gtcggcagcg atgaagaaag cggctggggc gatatggctt
    41761 attatttcga acatgaagaa gaaccagatt ttggtttctc accagatgct gaattcccaa
    41821 tcatcaatgg tgaaaaagga aatgtttctt tagctttacg cttcaaaggc gacaatgcag
    41881 gagattatgt cttgaaatct tttgtttccg gacttcgcga aaatatggtg ccaggaacag
    41941 caactgcagc acttcaagta ccaagtgcag atgcagctat cgcgatggaa gaagcatttt
    42001 accaattcat cgaagcaaat ccagtaagcg gaacgattga agcggacaat acgtatgtaa
    42061 aaatcgaatt agttggtaaa ggcgcacatg gtgcaagccc acaatctggt atcaatgcag
    42121 gttctttctt ggcattgttc ttagataact atgaattcct aggatctgct aaacaattta
    42181 tccatgtagc agctgcttat gtccatgaag atttttatgg agaaaaacta ggagtcgctt
    42241 atgaagatga aaaaatgggc aaattgacaa tgaatgctgg actatttgct tttgaagaaa
    42301 atggtacaga ggaagcgaac ttcatcaata tgaatttccg ttttccaaaa ggtgtaacag
    42361 tagacggatt gcaaagtgac atcgaacaaa cagtggggca agaaggcgca acagttactc
    42421 gaggtgctcg cgtaatggaa ccacattacg taccaatgga tgatccattg gtggctacat
    42481 tattgcaagt ctatgaagac cacactggag aaaaaggcta cgaacaaatc atcggtggcg
    42541 gaacttacgg acgtttgttg aaacgtggcg ttgcttatgg agcgatgttc ccaggatata
    42601 ctgatacaat gcatcaagca aacgaattta tgagtcttga tgacttgttc agagcaacag
    42661 caatctatgc agatgccatc tatcgtttgg cgaaataatt aattaaaaag aggatcaaga
    42721 attgcaaatt atttttgcag tcttgatcct ttttttactt tctactgtgg tattcatgat
    42781 aaacatgata tagattcaat tcatattctt tcttagcgtt cgtgacgact gtatccaaaa
    42841 tcaaccctgt tactaatgaa agaagtgcta aagtcatcaa tccagtactt aaaatcgcag
    42901 aagggatgcg tgtaataaag cttgtcagca tatattcgcg aatcacagga atccccgtga
    42961 ccaatccaaa taaaaagaag aaaatggtcc aaatcccaaa gaaaagcaaa ggcttataat
    43021 ctttaaacat tttaataatc atcatgatca ctttgaatcc gtcagagaat gtattcaatt
    43081 ttgattcgct gccttcagga cgatcacgat aatcgattgg gatttcaacg aacttgaatt
    43141 ttttatctaa agcatggatc gtcaattccg tttcgatttg aaaaccagaa ctcataatag
    43201 gaaaactttt gacaaagata cgattgaatc ctcgatagcc ggtcatgaca tcaagaattt
    43261 ttgttttata cattctagta attgtatttc taacaaggtt atttccaaaa tcgtggaaag
    43321 gtctcttatt ctcatcaaag taggttccat ttgataggcg atcaccaatg accatatctg
    43381 cttcaccaga acgtaatttc tcgagcaaac catgtacagc ttctgcagga taagtatcat
    43441 cgccatctac cattaaataa tagtcggcat cgatatcaaa gaacatttgg cggatcacat
    43501 ttccttttcc ttgacgaggt tcttttttta cgattgctcc accttgaacg gccaattcgt
    43561 atgttcgatc ggtcgaatta ttatcataga cataaatatc tgcttctggt aattctcgtt
    43621 taaagtctgc aatgactgtt gaaattgttg cttcctcatt gtaacaagga atcagaacag
    43681 caattttttc ttgttgttcc atttttcact ctccttaact atagaaaaca aaagctaaat
    43741 taaaaatacc tcataatcaa aggaaatgct agtttttccc gctaaatatc atttatttaa
    43801 aaagaaaata ctggaatata tgtttggaaa gctctatcta aaaaaccacc cactacaaaa
    43861 gaaggacatg atacctctct tttgaatagt gggtgcgtat tcgttctctc acttttttga
    43921 cgtattaatc tgttgcacct ttttttcttg aaatttctaa tacggttcct gtatgagcat
    43981 ctgctaaaaa ttcataataa acagtttcgc catcttctat tcgagaaaga cctccccgat
    44041 aagcactcga ccgaacggcg aatttcctaa taggttcctt ttcaaaagag atccaagaac
    44101 cttcgattgc accttctttt agaaaagatg acttgatatt ttcaagtact tggtctgctg
    44161 acaatacttt tttgcgatga taccaaatcg ttgaagctac cccgctcaat aatcctagac
    44221 cgattccaac tgctaacccg cctttaaaat agcttagttc gctttcttca tacatgtgga
    44281 catacctcct tcttctcact tgttactcct tgtgcttatt ttaccacact ctcatatttt
    44341 ctttgaaata aataaccgct accagaaaaa ataagctata ataaatacga tcggtctgca
    44401 gaaaaaatca tattttatcc gcagatcaat ataagtctga gaggagttta gtctgaaatt
    44461 tagacgaata gcatatggaa gaaaaaacat ttcaacgaat caaagagtta acagaattac
    44521 aaggaacaag cggttttgaa caagatgttc gcgcttatat ggaaagtcat atggaaccgc
    44581 tggtagatga gttacagtta gatggtttgg gcggcatttt tggtctgcgc catcatgaag
    44641 aagcggatgc accccgtgta atggtcgcag cacatatgga tgaagtcgga ttcatgctga
    44701 cacaaatcca agaaaacggg ctttttaaag tcgtacctct aggcggctgg aatccttacg
    44761 ttgtttctgc tcagcgtttt acacttaaaa cctctactgg taagaattat ccatgtattt
    44821 cttcttccgt tcccccacat ttattgcgag gaacaagcgg acaaaaatca gtagaagtaa
    44881 ccgatatttt gttcgatgct gggtttgaat caagagaaga ggcaatgagt tacggtgtcc
    44941 ttccaggaga cacaatcgtt ccttacgctg aaacgatcaa aacagccaac ggaaagaata
    45001 ttatcagtaa atcatgggac aaccgctatg gctgtacaat ggtattagaa gctttagaag
    45061 cgttgcaaaa tgaaacatta ggtcatacat tgattgcagg cgcgaatgtc caggaagaag
    45121 taggcttgcg tggttctaaa gcttctgtca ataaattcaa gccagatctg ttctttgcag
    45181 tagactgctc tgcagcagat gatacagtga cgaaaaatgg cacattcgga catttaggag
    45241 aaggtacatt gatgcgtatc caagatccag gtttgatcat gcttcctcgt ttgcgcgagt
    45301 acttgctgga tatcgctgaa acaaacaata tcccttatca atactttgtt tcaaaaggcg
    45361 gtacagatgc aggtgctgct catacacaaa acgaaggaat cccaagtaca gtgattggcg
    45421 tagtgggacg ttatatccat acgcatcaaa cgatgttcag tattcgcgat tttgaagctg
    45481 cacgagaaat gttgattcaa acactgaaag gtttggataa atcaacagta aatacgatcg
    45541 tatacggaaa ataatgcgat agtgaaacta taaaatctgg caaaagattg ctttttgcca
    45601 gatttttttt ataaaaagag gatcaatgtt tgttagttcg aaagaaaggt gtataattta
    45661 attgaaaaat acataaacag aaagtagagg acaaagaatg attatcccaa atagtttaga
    45721 agaattagca ggctacgtag aaactggaaa gagtgtattt ttctttactg ccggctggtg
    45781 cggagactgc cgttttatca aaccgcaaat gcctgaaatt gaaaatgact tttctgattg
    45841 gcaatttatt gaagtagacc gtgacaagta catagatgta gccgctgaat ggaacatttt
    45901 tggtatccca agttttgtcg tgatccaaga cggaaaagaa ttaggtcgtc tagtgaataa
    45961 agatcgtaaa acaaaacagg aaatcgaatc gttcctagaa agtgtaacaa aaggctgaca
    46021 tctgttagga ggggtcaaga tgaatcaaga atataagaat attttagtag gtatcgacgg
    46081 tagtgaacaa gcacttgctg ctttcaaaaa agcggtagaa gtggctcgcc gtaataatgg
    46141 gaaagtatat gtagcaaacg taatcgatca gcaattttat aactttatgg gctatgcacc
    46201 tattgatcaa aatctagtcg atcagcaaac tgaaacagcc aaggaaatga tcgaagaatg
    46261 taaagaatat gggaaatctg ttgattacac aaatatagaa ggaattattg catatggttc
    46321 tgttcgtgaa tccatggcag tcaaattgcc aaaaaaatat gagatcgatc taatcatggt
    46381 tgggcagtca ggtctaaatg cagtcgaacg ctttatgaca ggaagtgtag ccagctacgt
    46441 gatacgtcat tcaccttgtg atgtcttgat cgtttctgac gaagaagaac agccaagtaa
    46501 ttaagcaagt ggaacttgta cgaccttttt aatcaattaa ctaaaacagt aaagggactg
    46561 tgacaaaagt cttgtcacag tcccttgtta cgaataaatg gtgttccaga agaggcttct
    46621 tcggaaataa agcatgaaaa aaatttcatg cagtgaatgc aattttttgt taagataaat
    46681 ctcagcaaag gataatggag gaaagaacat gatttttgct tataacaaag cacacgtcgg
    46741 agacaccttg atggttatta tagccgacga taaaggaaca gaaaacactg ttgaacgcaa
    46801 atggaatgtt gctcggatca aagatgaaca aggtcaagtt gttgcttgga actttttcca
    46861 tatctccgat catctaacaa tcgaagggaa cggccaagta agcttaacag atgaggaatt
    46921 agcgaaattg aatcgattga tcaaagaagc aggattcgaa gaacagcttg aagctgatca
    46981 tgaaccgaag atcgttgtcg ggtacgtaaa aacatgcgtc ccacatcctg attctgacca
    47041 tttatcgatt actgagacag aagtagacaa tggtacagta ttgcaaatcg tttgcggtgc
    47101 acccaatatc gaagctggac aaaaagttgt cgttgcaaaa ccaggagcta tgatgccaga
    47161 tggaatgatg atctggccag gaactttgcg aggggtagat agctatggaa tgatctgttc
    47221 cgctcgtgaa ttgcatttgc caaatgctcc agcaaaaaaa ggaatcttag tattgcctga
    47281 ggatgccgta gtcggagaag catttccaaa ataaagaggt tgtgacaagt ctttgtcaca
    47341 acctcttttt tattaatttt cactattttg attttgtttt aatgccgatt gatcgatcgt
    47401 caattcaaca gtagttgttt tttctttcga gccttcatag taagtgattt tgacagaatc
    47461 tcccactttt ttcttataca aagcagattg aagttctaca ccagaagaaa cttctttgtc
    47521 atcgatctta gtaatgacgt cgtattgttt caatccagct ttttcagccg gtgtagctgt
    47581 ttggacattt gtcacgatga caccgttagt tacagatgaa ggaatcttca agatttgttc
    47641 ttgttgctga gtagaaacgg cagataagtc gaccattgtg atacctagag ctggacgtgt
    47701 cacttttccg tctttttcca gttgattgat gatattcact acatcgttac ttggaatagc
    47761 aaatcccatt ccttctacgc ttacattaga agtagattca gaagtacttg cgatcttact
    47821 tgagttgata ccgataactt gtccttcgat attaactaaa ggaccaccag aatttccagg
    47881 gttgattgct gcatctgttt ggatcgcatt gatattgact gtttcgttcg attcattcgt
    47941 acttgtcact tgtcggttca aggaagaaat gattcctgaa gtgacagaat ttgcatattc
    48001 agatcctagt ggggaaccaa tcgcaatcgc aggctcacca accttcagag cacttgagtc
    48061 accaaaagag gcaactgttt cgactttgtc tgaattgatc ttcaacaccg ctaaatctga
    48121 ataagcatct gttccaacta attcagcttt taccttcgta ccgtctttca tcaagacttc
    48181 aagaccttgc tggccatcta ctacgtgatt attcgtgact acataagcag tattcccgtc
    48241 ttttttgtag atcacgccgc ttccttcact ataagcttcc aaattactat catctgagct
    48301 gctactttct tcttgctgcc cgaatagtcc gccaaaaccg cttgattggt tttgactttg
    48361 taagttgata acagaaacga cagcgtcttg aactttatct accgctttgg tgatatcaga
    48421 atctacattg actttgacat tttccacaac tgtttcaccg gcagaattct gattgccgct
    48481 tgtagcagta gaactattgt tgccagtgcc catcgctgca taaaaaatgc cagctgtcag
    48541 tagtcctcca acgatccctc caacaagccc cagacctaac ttacgccaga ggctattatt
    48601 tttacttttt ttcatctttg gtgtcacatt ttttctatcc atgtgttcct cctccaatta
    48661 cattcattta tctactgtta gtatagtctt atttgttgac tttagtctac tttgagactg
    48721 tgaacttttt atgaaaaact ttaggaaaaa tcattgtttt cagatgaaaa tatttgattt
    48781 tctttttcca cagatactgt gtaaaactac gcggatagga ttggaaaaat aagggataaa
    48841 acatatccac agcctgtgta taaagtggat aaattcttat aaaacgtatg tttgcctaat
    48901 gaatgtgatg aaataaggta aaataacact gttttctgtg gataaacctg tggatgttgt
    48961 gcataactgt tggggaaatc tttttaacaa aaatagccaa aataaacata tagacgaaaa
    49021 aattgattat aataaacaaa gtgagcatga agaccaaagg agagaaaaca tgaatatcaa
    49081 aattatctca gtaggaaaat taaaagaaaa atacctgatc caaggtatca atgagtatgt
    49141 caaacggctg aatgcctatg caaaaatcga attgatcgaa gttcctgacg aaaaagcccc
    49201 ggagaattta agcgaagcgc aaatgagaca agtaaaagaa aaagaagggg aacggatctt
    49261 agcgaaaatc aaagaacaag aatacgtcta tgccttagca attgaaggga aaaatcctac
    49321 aagtgaatct tttgctaaac aaatcgacca attaggtatc caaggaaaaa gccaccttgt
    49381 ttttgttatc ggcggctctt taggactcag cgaagccgtc atgaaaagaa gcaatgctca
    49441 gatctctttt ggaaaaatga cgtatccaca tcaattgatg cgtctgatcc ttgtcgagca
    49501 aatctaccgt gccttccgga tcaatgcggg ggctccatac cacaaataat gatatttttt
    49561 aagagaaaaa attatcccta ttttaaataa tagcaatagg tagtggtagg gagaaattta
    49621 taaataactt ttttatttgc tttggtagcc aagtaagttg caaaagaaaa atagatactg
    49681 ttaaaaagat aatgtagaca tagaaacaaa tacgtaaaat tttagttaga ataatggcaa
    49741 ggagaaaaaa catgatagat gaaaaaaagt gtttaaaaaa tctattagag gatatggatg
    49801 atattgaaga aaactatcta aatggactgg gaaaacaaat atatttcaga tacttaagct
    49861 atctaaaaat gaaataagac atagtaattt tttagctttt ttgtttgctc caaatgaaac
    49921 ccacaattta tctgatgagt tttttaaaat gtttttgaaa aggtatatag attctaatga
    49981 tgataccaaa gctgctatca attattttga tgctttactt aatagctatg aagatttaat
    50041 tgtttacaga gaaaataaga atattgatat tttattggta tcggaaaaaa ataaaatagt
    50101 ggtgtgcatc gaaaataaaa ttctgtcttc ggagtctgga gggcaactta ataaatacca
    50161 aatatatata gaacgcaatt attctaacta taaaaaaatt tttgtttttt taactccaga
    50221 tggaaatgaa cccacaaatc ctagttgggg cataattact tacaagaata tcgttga
//
LOCUS       DAFELK010000015        47739 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFELK010000015
VERSION     DAFELK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.016"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..787
                     /locus_tag="LP433_001083"
     CDS             <1..787
                     /locus_tag="LP433_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL2005262.1"
                     /translation="NLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNN
                     EIKNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKS
                     QYGDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEV
                     APILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTD
                     FYRNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(856..1455)
                     /locus_tag="LP433_001084"
     CDS             complement(856..1455)
                     /locus_tag="LP433_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2005263.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            1709..2590
                     /locus_tag="LP433_001085"
     CDS             1709..2590
                     /locus_tag="LP433_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005264.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            2603..4213
                     /locus_tag="LP433_001086"
     CDS             2603..4213
                     /locus_tag="LP433_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBL2005265.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(4290..4949)
                     /locus_tag="LP433_001087"
     CDS             complement(4290..4949)
                     /locus_tag="LP433_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2005266.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(5232..5897)
                     /locus_tag="LP433_001088"
     CDS             complement(5232..5897)
                     /locus_tag="LP433_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBL2005267.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(6044..6649)
                     /gene="dhaL"
                     /locus_tag="LP433_001089"
     CDS             complement(6044..6649)
                     /gene="dhaL"
                     /locus_tag="LP433_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBL2005268.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(6677..7687)
                     /gene="dhaK"
                     /locus_tag="LP433_001090"
     CDS             complement(6677..7687)
                     /gene="dhaK"
                     /locus_tag="LP433_001090"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBL2005269.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(7662..8108)
                     /gene="dhaM"
                     /locus_tag="LP433_001091"
     CDS             complement(7662..8108)
                     /gene="dhaM"
                     /locus_tag="LP433_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBL2005270.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            8211..8531
                     /locus_tag="LP433_001092"
     CDS             8211..8531
                     /locus_tag="LP433_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBL2005271.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(8643..9512)
                     /locus_tag="LP433_001093"
     CDS             complement(8643..9512)
                     /locus_tag="LP433_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2005272.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(9608..10912)
                     /locus_tag="LP433_001094"
     CDS             complement(9608..10912)
                     /locus_tag="LP433_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2005273.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(10909..11418)
                     /locus_tag="LP433_001095"
     CDS             complement(10909..11418)
                     /locus_tag="LP433_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005274.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(11593..13728)
                     /locus_tag="LP433_001096"
     CDS             complement(11593..13728)
                     /locus_tag="LP433_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2005275.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(13811..15466)
                     /locus_tag="LP433_001097"
     CDS             complement(13811..15466)
                     /locus_tag="LP433_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2005276.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(15468..15782)
                     /locus_tag="LP433_001098"
     CDS             complement(15468..15782)
                     /locus_tag="LP433_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL2005277.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            15952..16212
                     /locus_tag="LP433_001099"
     CDS             15952..16212
                     /locus_tag="LP433_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBL2005278.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            16226..16540
                     /locus_tag="LP433_001100"
     CDS             16226..16540
                     /locus_tag="LP433_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBL2005279.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(17270..17824)
                     /locus_tag="LP433_001101"
     CDS             complement(17270..17824)
                     /locus_tag="LP433_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBL2005280.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(17950..19879)
                     /locus_tag="LP433_001102"
                     /pseudo
     CDS             complement(17950..19879)
                     /locus_tag="LP433_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(20185..20901)
                     /locus_tag="LP433_001103"
     CDS             complement(20185..20901)
                     /locus_tag="LP433_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL2005281.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(20902..22725)
                     /gene="glpO"
                     /locus_tag="LP433_001104"
     CDS             complement(20902..22725)
                     /gene="glpO"
                     /locus_tag="LP433_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBL2005282.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(22739..24235)
                     /gene="glpK"
                     /locus_tag="LP433_001105"
     CDS             complement(22739..24235)
                     /gene="glpK"
                     /locus_tag="LP433_001105"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBL2005283.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(24371..25831)
                     /locus_tag="LP433_001106"
     CDS             complement(24371..25831)
                     /locus_tag="LP433_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005284.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(25821..27116)
                     /locus_tag="LP433_001107"
     CDS             complement(25821..27116)
                     /locus_tag="LP433_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2005285.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(27448..28125)
                     /locus_tag="LP433_001108"
     CDS             complement(27448..28125)
                     /locus_tag="LP433_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBL2005286.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(28155..29246)
                     /locus_tag="LP433_001109"
     CDS             complement(28155..29246)
                     /locus_tag="LP433_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBL2005287.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(29347..29781)
                     /locus_tag="LP433_001110"
     CDS             complement(29347..29781)
                     /locus_tag="LP433_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2005288.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(30365..31822)
                     /gene="ascB"
                     /locus_tag="LP433_001111"
     CDS             complement(30365..31822)
                     /gene="ascB"
                     /locus_tag="LP433_001111"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL2005289.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(31819..33714)
                     /locus_tag="LP433_001112"
     CDS             complement(31819..33714)
                     /locus_tag="LP433_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2005290.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(33772..35547)
                     /locus_tag="LP433_001113"
     CDS             complement(33772..35547)
                     /locus_tag="LP433_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL2005291.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(35597..37093)
                     /locus_tag="LP433_001114"
     CDS             complement(35597..37093)
                     /locus_tag="LP433_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2005292.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(37287..38909)
                     /locus_tag="LP433_001115"
     CDS             complement(37287..38909)
                     /locus_tag="LP433_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL2005293.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(39237..40550)
                     /locus_tag="LP433_001116"
     CDS             complement(39237..40550)
                     /locus_tag="LP433_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL2005294.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(40795..41019)
                     /locus_tag="LP433_001117"
     CDS             complement(40795..41019)
                     /locus_tag="LP433_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005295.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(41039..41461)
                     /locus_tag="LP433_001118"
     CDS             complement(41039..41461)
                     /locus_tag="LP433_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBL2005296.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(41603..42313)
                     /locus_tag="LP433_001119"
     CDS             complement(41603..42313)
                     /locus_tag="LP433_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005297.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(42331..42828)
                     /locus_tag="LP433_001120"
     CDS             complement(42331..42828)
                     /locus_tag="LP433_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2005298.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(42865..43317)
                     /locus_tag="LP433_001121"
     CDS             complement(42865..43317)
                     /locus_tag="LP433_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2005299.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(43452..44057)
                     /locus_tag="LP433_001122"
     CDS             complement(43452..44057)
                     /locus_tag="LP433_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL2005300.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(44507..45127)
                     /locus_tag="LP433_001123"
     CDS             complement(44507..45127)
                     /locus_tag="LP433_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL2005301.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(45129..45998)
                     /locus_tag="LP433_001124"
     CDS             complement(45129..45998)
                     /locus_tag="LP433_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBL2005302.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(46021..46428)
                     /locus_tag="LP433_001125"
     CDS             complement(46021..46428)
                     /locus_tag="LP433_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL2005303.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(46447..47736)
                     /locus_tag="LP433_001126"
     CDS             complement(46447..47736)
                     /locus_tag="LP433_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2005304.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        13450 a        10151 c         8168 g        15970 t
ORIGIN      
        1 aaatctttcc tttaacgggc ttgcgctacc tgaaggaaaa aaaccattgg ttctttcaca
       61 agatgatgtc agctattatg aatatatgga taattccggt tttcctagcc gattggtcgt
      121 atcaaataac aatgaaatca aaaatgtcta taaagagaaa gataaagaag aaatcggtga
      181 ctttgacatg gttcctctga tcgatgcctt tgtcaagaaa catcctgatt tttcttatcg
      241 aggcgcaaaa ggtaccttgg ccctgacagg ttacaacgga gttttaggtt atcgaacatc
      301 aaaatctcaa tatggagaca atgaaaaaac aaaaaaagag attaaagaag ctaaaaaagt
      361 ggcggaacag ttgaagaaag acggctggag ctttgcttcc catacatggg gtcacttgaa
      421 tatgactcaa gcttcactag aagatgtaaa aaaagacaat gaattgtggc agcaagaagt
      481 tgcacctatc ctaggaaaaa caaatattct gatttatcca tttggtgcag acatcagcga
      541 ctggcagcct tattcagcag aaaatcaaaa atttgcttac ttgaagagtc aaggtttcga
      601 tattttctgt aatgtcgatg cttctacacc agcttgggga caattaggta cggatttcta
      661 tcgaaatgct cggatcaata tcgatggcat tcgttttcaa tctgatttag acggaaaaaa
      721 tcctattctt gatccattca tcaatgtcca tgatgtctat gacaaagaag cacgcgaatc
      781 tgcttgattt tacgtcattt atgaaccaaa aaagccgaac tgacatttta tcgtcagttt
      841 cggctttttt atgctttatt tcttcttcgg tgcgattccc ttgatcagga cttctgtcca
      901 ttctgctgta tatggaagca gttttgcgta tatctccggc ttagaaattc cttctaccat
      961 tgcttgaaaa tagaggatca agaactcatc cgaatatttc aaatccactt ttccttcttt
     1021 ccgccctcga tggaaaagat caagcatgat actgaaactt tcttgcgtat acgcatccat
     1081 cgcgtcagaa aattcttttt tttctttttt tgtatagtat gtcatcaaat cgatataaaa
     1141 ttgtttgttc actcgattga gataacggat tttgttttca ctcatggcaa tcagtgtttc
     1201 ttcaaatgga agattttccg caatcaacgc tttcgcttct tgccctaaat cattcataaa
     1261 tgcaaaaaat acttcataaa tcagcccttc cttgctgcca aaatatttaa aaatcgtcgc
     1321 tttacttacc tgagcgttct cagctacctt atccattgtc actccagcgg ttcctatgtc
     1381 tgtgttcatc aagtcaaaag ctgcttgtaa aatctctttc tttttctctt gtgctctctt
     1441 ttcaaaaccg ttcatttgta gagcctcccg taattttaaa cttttataat atatatagtt
     1501 caaatttatt ctgaggttta ttataactat ctattgagaa agtatcaagc tagcaattcc
     1561 ttgtttatga attcattgac agaaatttat aaaaagaata ttatgtacta aaataataaa
     1621 aaaagtttta taaaaaggta taaaaccttt ttattaaact atttaatctt gtttagtata
     1681 tatttttaga aaaaggagtg gggtttttat ggcagaaatc gtcaaagtca cacatttgaa
     1741 aaagagcttt ggtcgtttcg aagctttaaa agatgtctct ttcaccgtac attcaggtga
     1801 agtcgttgga tttatcggac caaatggttc tggaaaatcc acgacgattc ggacactttt
     1861 agggattata aaaaaagacg gcggaacggc aacgattttt gggcaagatg tatgggaaga
     1921 tagtttatct atccatgaac gtctttctta tgttccaggc gatatctctt tgtggggaaa
     1981 tttgactgga ggagcgatca tcgatctctt catgaagctt catggaaaag ggagtgctca
     2041 aaaaaaagat gaactgattc aacgtttctc tcttgatcct aagaaaaaag caaaaaacta
     2101 ttcaaaagga aatcgccaaa aagtgggctt gattgctgct ttggctgttg attcggatct
     2161 ctatttattt gatgagccta cttctggttt agatcctttg atggaaacga ttttccaaga
     2221 agaagttgaa aaattgaaag aacagggcaa atccatccta ctttcttctc atattctcag
     2281 tgaagtcgag cgactagcgg ataaagtcgt gatcatacgc gaaggaacac tcgatgaaga
     2341 aggaacactc gatgaattgc gtcatttgac tcgttcgacc atcactatag aaacagaagc
     2401 agagaatagt cacttagcac aattgaacgg tgtccatgac tttgtgcaaa aaggtcacct
     2461 cgctcaattt gctgctgata acgaagcttt cgatgtgatt ttagctgaag cgtccaaatt
     2521 aggtgtgaaa aaatttgaat ctattccacc gactcttgag gatttattca tgagacatta
     2581 tgaaggatga ggaggaagcg aaatgactga taaattttca cgctggtcca cccttttttc
     2641 tcaaaacctt agccgtgact ggaaaaagat cctgatatgg ctagtcggtg tcactgcttt
     2701 ttctggtggt tttgtccctg cgtttgaaga attgacttcc ggacaaggat tagctggatt
     2761 atacgaaacc ttgcaaaacc cggcaatgat tgcaatggtc ggaccaactc cagcttcgaa
     2821 tgctgctgag tatactttag gagcgatgta tgcaaatgaa atgttgcttt tttgcagttt
     2881 gtttgctgct gtgatctctg ttttacacgt ggtgagccaa acgagaaaaa aagaagaact
     2941 tggtctgatt gaacttattc gttcctttcg agtcggacgt caagcaaact ctttagctgt
     3001 catcgctgaa agtattctga tcaatttgct tttagcaata tcgatcagct gtacgatgat
     3061 ttttttccaa gcggattcga tcactgcaga aggtgcttgg ctttttgggc tatctgtagg
     3121 tagtatgggg attttgggga gtgccgttgc actgtttgct gcacaactga tgccaagttc
     3181 agccagttcg aatggtctgt ctttagcgtt tttaggtgga ctttaccttc tacgagcaat
     3241 aacagatgta gctgattcct ccctttcgat gtggaatcct ttaggctggt cttatttgac
     3301 ctatccattt acaactaaca actggattcc tttgctttat ttgtttttgt tcagtctaat
     3361 cttgataatc agttcatttg ttttagagga acatcgagat ttgaacaccg gctatatccc
     3421 cgaacgtgaa ggaaaaccgt atgctaaacg ttctctttta tccttgcgtg gtttattatt
     3481 ctatctaaat aaagggatga caatcagttg gcttatcact tttggtttga tgggggcggc
     3541 atacggctct atctacggga atatgcaaca gtttttagaa agtaacgact taatgaaaca
     3601 gatgtttatc caatctggcg tctcaattga aaaaaacttt acaagcacga tcatggtagt
     3661 cttgatttgt ctagctgcta ttttaccaat tgctagcatc aatcgtttat ttacagaaga
     3721 aacccacgga cgtatgaatc agctgttcgc aacaaaaatt tctaggaacc aactttattg
     3781 gaccaatatg ttactagcta ttctatttgc tatattggca atcctgatta gttctggtgc
     3841 actagggctt tctgctttgg cttcgatgaa ggatgcgaaa gacatggatc tattgatgtt
     3901 tcttaaagcc gggttcaatt tcctgcctgc cgttttagtg tttatcggaa ttagtggctt
     3961 tctattcgga tggcttcctc gaatcggtaa acttgcttat atctacttag cttactcctt
     4021 tgcactcaat tactttggcg gaattttgga tttaccagaa tggttttcca aaacagctgt
     4081 ccctagctgg gttccacgga tgccaaacga ttcttttgat ctttccgtgt tccttacgtt
     4141 atcatgtatc agccttgcac tgttcgtcct tggttctatt ggttataggc gaagagactt
     4201 actagaagga taataaaaaa gcatgtacaa tttcatgcta gcctccaaat ctgggtcaaa
     4261 aatccaacat ttggaggtca tttttttatt tacaagtctt ctaactgctc tttatcaatg
     4321 atccagactt ctcgattctt tctttttaca taaccattct cctctaataa tttaaatttt
     4381 ctagataaag tttcgggggt cgtaccgata aatgcagcaa gttctttcat tttcattggc
     4441 aggaaaaagt gatccttccc tgtcgcttta gctaagtcaa gcagatagac agcgactcgt
     4501 tcttctactt tttccatcat caaaaaagtt gtctgctgct gtacttttgt taatttctca
     4561 acgttgattg ctaaaagttt cagactaagg gcgggataat gcagtaagag ttccgagaaa
     4621 tctttttgtc tcaatatgca aatttccgtt ttttctagtg cttcgccaaa taaagactca
     4681 tttggaacgc ctagcaactg gctctctccc tcatatccgc ccggctctat tactcgtaaa
     4741 agctgttcct ttccgctagc agataattga tacactttca tactgccgga ggccacgatc
     4801 actaattgag gttctccatt cggcgcaaga atctgttctc ctttttccac atagtgatgt
     4861 ttgacaagtg cgtgtacttt ttcttgatct tgctgtacta agtgattgaa caaaggaaca
     4921 aatgaaacac ataaatgatc atgactcata atctctcctc cttctaaaca gctatttcta
     4981 ataaagaaac ataacttccc ttattccaac tgataatttt cttttatcat agcataaacg
     5041 tcaagcgaac cagataccag caaatagagt ggatttcttt ttgtcccttg ctttattttc
     5101 cttcttttga gaccttaagt aattgattcc tatcaatttt ttaaatattt actttttgaa
     5161 taatcaaaaa caaaccttca ctcgcaagcc gagagtaagg tttgtttttc gcattgctta
     5221 tttcgtgttg tctattgaaa tttttccgca cctagctttt gatatagtgg tgctagttct
     5281 tgtaaggttt cagcggttat ttgctcaacg tgttcgattt cttgcggata gaagaatagt
     5341 ttacccattt gaaaggttcg gtctctcatc gcttttttca actcttcttg tttctttgta
     5401 tcggacaaat agtcagacaa agctaagtgg tcgtcaagtt catgttctgg ttgcggccat
     5461 atgtaataat ccttgatatc gactgttttg ctccactctt tcagtatcgc aagcaactgg
     5521 ttatacgctg caatgctacc atatcgttct tcgcttttat aatgttggta catcaaatag
     5581 atttggtatt gtttttgatt caacaaaact gctagacagg cattctcgtc ttgacgagat
     5641 tcgcttcggt acgcgctcca aaaatgactg cgtaaattcc agccattcgt ccagctttcg
     5701 attttaggtt tgctcatgcc gtacatatca ggcaaaagtg cagctgtctg gagctgaatc
     5761 tctttccatt tttgccagtg ttctttatat tctttcttga tttgttcaat cttatctgtt
     5821 ggatggctct ctttgagctg tttgaatgcg tagattggtc gatcaaacaa ctgataatct
     5881 gattttccaa gttccattgt ttcgcctctt tccgttatct tttgtattct acctgaattt
     5941 tgcgatatgg acaaatagag gttgtgaaaa agctgttctg catcaagtca taagaacagc
     6001 caaacaaaaa actgcgatga gcatcaccgc agttttattg aacttaaggt tgattgatca
     6061 catctaaaag cgttgaaaat aaaatggcac tagaagcagc tcctgggtcg atatgtccga
     6121 ttgcacgctc tcctagatag gaagctcgtc cttttttagc taccaagact ttggtgtgtt
     6181 cttttgcctg gtcaatgatt tcttttgtta aattccctgc cttcaatgcc tctgtgactg
     6241 gcagccaaac atctaacatc gttttatcgt cagcttctgc ctttcctcgg ctttgaatac
     6301 ccgctgttcc ctgctcgatc acttcgccta atttttcttg agaatcaata gaatcgacct
     6361 cttttgtcgc tttcatcatg ttcatgaatg cagatccgta taacggacca gaagccccac
     6421 cgactttcga tatcatcgcc atagagaata ctttgaatgt atcgctgatt gtttcaggat
     6481 gatcggcttg aaaagcttct tcataagctg aaacccctct tcccatgtta tttccatggt
     6541 ctccatcgcc aatcggggta tctagatcac tgagatattg tttgttctga ttgattgcct
     6601 ctgcaaattg cgtgagccat tcttggattt cttgaacggt tagtttcata ttatcaccct
     6661 tttatcttga gattttttac catgaaatcg tctgtacatt gctttctaaa gaatctttcc
     6721 attgtgtctc cgtcaagtcg atcagtgtta gagaaagacc ttgcatatct agtgaggtca
     6781 taaaattacc gacttttcgg aaaactacat tgacgcctct ttcttccaac agagctaaaa
     6841 catcattcat gaacacgaac tgttccatca aaggcgtccc gcccattccg ttgactagta
     6901 cacctgcttc ttttggtaaa ttcgagtaat catctaaaat cttagtaaca agttcctttg
     6961 ccagtacttt agaaggctgc atcttttctc gacgatagcc tggctcaccg tggataccaa
     7021 caccatactc gatctcatct tctcctagtt cgaatcctgg tttccctact tctggtacag
     7081 ttgctgctcg aagcgctaga ccgatcgtct tagttgcctg tacgaccttt tctcccagtt
     7141 ctttcaactc agctagggaa gcaccgtttc ttgctgcatc gcccacgatt ttgtgtacaa
     7201 ggacagtacc tgcaactccg cgttttccag cagtatacgt actattttca acggcgatat
     7261 catcatctac gatcacactt tctacttcaa tatcgtccat agcagctaat tcctttgcca
     7321 tatcgaagtt caatgcatcc cctgtataat tcttaacgat cagcaaaact ccttttccac
     7381 tatcggcttc cttaatagcc gtctgaatct gatctggagt tggagaagta aacacatcac
     7441 caagcaccgc tgcacttaac atcccttccc ctacaaaccc ggcatgggat ggttcatgtc
     7501 cgcttcctcc accagaaacc aaaccaactt gttccgcttt ctgattcttg gctacaacac
     7561 gggaagattc tacacgatga acaagttctg gatagctttt tactaatcct tccagcattt
     7621 cttcgacaat attgcttgga tcattcatga tttttttcaa tttattccca tcctttcttt
     7681 ccggcatttt gtgcttctgt taagatttgc tgagtatcat ctgttatacc ggcagtgatg
     7741 gctgctgcaa aagctccttc cactaaaggc gcatccacca gatgataacg ttgctgctgc
     7801 tcttcttcca acatgtcttt tgccagttcc gagttcaata ccgcgctacc gatatccgca
     7861 aaaacaaaat aactagctgc atcgcttgat tcattgactg cttctacgat tttcatcggg
     7921 tctgatccga tctcgccatt tattccgccg agagaaaaaa tttgcacctc ttcggatttt
     7981 tgcatctgct caatcatttc tttaatacca tctgttactt tttgactatg agaaataagc
     8041 aaaatacttt ttttcacaag aatcttcctt tcttttacat agttgctaac gattggtttc
     8101 gctttcatta atgaacaatt caagtatata ataaatttct aattttggga aaatatgtgt
     8161 agtgcttctt gaagtttgtt atactttaat taaaagagag gagtgatcga atgattacaa
     8221 caacaacgaa cagtgtagag ggaaaagccg tagtagctta taaagggatc gtttttggtg
     8281 aggtcattac tgggatccat gcatttaaag acttggaggc ggggttgcga aatatctttg
     8341 gcggccgctc aaaaagctat gaaaacgaac taatgggtgc aagagaagaa gcacttgccg
     8401 aaatggccga acgtgcaaaa gcattaggag ctgatgcgat cattggcgta aaaatggact
     8461 atgaagtatt aggcagcgac aatggcatgc tgatggtcac atgtagtgga acagctgtct
     8521 ccacgagata agtaggggac atctgtttta ataactaaag agagatggga catgtagtgg
     8581 cactcaagaa ttagattttt cagtctaact tcgaggtact ctaccttccc atcctctctt
     8641 ttttatttct ttttgcggat gattccgtaa gctgctgcga ctaacacacc cgcccctgct
     8701 aaggaataac tgacagaagc tgttttttca tttgtttttg gcaaagtctg acttgttgat
     8761 ttggatggct ctgtcgtttg ctgaactgtt tctgtcgtgc ttccagaggt cactgatttt
     8821 tctcctgccg aatgcaaaat atcttttatt cgttggaaac tagctgctaa gtcagctttt
     8881 tttgcttcaa aatcattagc aactgtttgt gcttcgctga tctttccgtg gattgcttga
     8941 ctggccgctg tgatatccgc ttgagtttga cttagctttc cagaagctgt ttgagcaacc
     9001 tgatttaatt gctgattgaa ttcttttgct tgttggatct tcccgtcaag atctgtttgg
     9061 acagcttccg cttttgcttt cgcttcggca agctttttct caagttgtgc acggtcattt
     9121 cccactttat ttttaagatc agctaaatct tgatcgattg ctgcttggtc ttctttcaat
     9181 ttgttttttg cagcttctaa tgcttcttcg agttcttttc ttttattttc caagtcttgc
     9241 aaatgatcga tttggtcaga agaggtagaa ctatttattg atgtatcttc tgaagatgaa
     9301 atcgtttctc ctgaattatc tgtcggtaca ttggaagtca tttctgtttc cgaggcaccg
     9361 ttttcagcac cagaagagct tatggttgtt gaaggttctg tttgagcagg ttcagaagtt
     9421 tccgcaaaag ctgtctgtcc caataagaaa atactggaaa cagcaattgg ccagattaac
     9481 ggcttcattc tttttttcat cacttttccc atccttacta ctttttaact aatttcttat
     9541 tataagcaaa aatgtttgga agaaccataa acacaacagg ctgtttgtct aaaaaacggt
     9601 gcatctttta tttttttgta cgttccgggc ttttccatgt cccgcttcca taacctaaaa
     9661 tcgttttgac tgctggaatg aaagtcgtca cgatcgttat cgcgttcact atccagaaca
     9721 aaagcatata tagtggtgcg aaaagaaggt atttcaattt tcttcgtcga tcatctacaa
     9781 tcagcgaagc tagcaactgg aaaaatcctg cgaccatttc aaagcagatg aacacaaaac
     9841 tgaatgtaaa agtaatataa atctgttcgt agtttccttg atatacataa tgcccgatta
     9901 atccagcaaa aagaactacg gaaatacaaa agaatattga ccagacaata ctcaatgttt
     9961 gatcaatgaa gatgatcgtt cttccaatat gtttaaaagg atggagcatc acttttttga
    10021 aattcgtcag ccagacttct gttccacctt ttgcccaacg ttttctgtgt cgatatagca
    10081 tcttcaacgt cacaggtact tccatgaaaa agataatctc aggagcaaaa acagataacc
    10141 agtcatttaa ctgatgatcc caagcaatac tgatgtcttc tgtcgctcga tcttgtctga
    10201 atccgcccac atcgatcaag gcttcttttc gatacatcgt atttgctcca ctgtacgcat
    10261 aaagaccacc gaaaacagct gactgtgttc gtttaatgat gcccacgata cttgagaatt
    10321 caaccgtttg agattttgca atcaatttgg tacgattttg gacatccata tttgcagtga
    10381 ccgcagcaat atgtcttgca ccagggcgaa tgaaataatt cacataccta atcagtgcat
    10441 ctggctccgg taccgtgtct gcatcattgc ttaaaatcaa tttccctttt gcaaaggcaa
    10501 gtccgatatt aaacgcgtgg gcttttcctt tatttttttc gatccgaacc acacgaagat
    10561 tagcgtattt tttcatcagt ctagctaata tttctggtgt ttggtccgtt gaaccatcgt
    10621 ctgtcactaa tacctcatag ttgtgataat tcaatttcgt catcaaatac tcgattgtat
    10681 attcgatcac aatttcttca ttatgggctg gcaccatgat cgtgatgaac ggttcgacac
    10741 tcaagggaac atctacccat tctttttgct tatgtttgta taaaaacaca taacaccaga
    10801 caccaataaa ccatacaaat ccgcctaaaa tcggataaga aacgagaaaa aaatacataa
    10861 tagacaaaca agtatctaag aataaattac ctgtatgggt gattgagatc atttcagttc
    10921 caccccattt tctttataca aatctgcaat gaatgtcgta tctagatttt tctcttcgga
    10981 gacagaataa aaacggaccg tttctctctc ttcttttgtt ccaaaacgtt ccgtatacac
    11041 ttcttcaagt aattcttgtc tttttttcaa tttttcatct tcatattcaa aagatttatt
    11101 tacttttttg tatagatttc gattgttcca cctagtcaat acaaatgagg taatcaggaa
    11161 actgaaaaaa atcaatacaa aaaagccgat taagaaatac agcattttct tttctgataa
    11221 aaaagcgtac aaggaaaaat ccttggctct ttctggtctc gttaatggga aaaagaccca
    11281 tataaaagga agaacaacga tcatccatcc taaaagagcc actaacgttt gccaaatctt
    11341 taaccagtaa ttaccttttg aaaaatactt atctttcacc aaaattgatg caacttcttc
    11401 tcttgttact tttttcatat cctcacctca cgtttttttg ttacgacgta ggagtttacc
    11461 atacatttca tttcttttca cataaagtgt tcctaaattt ttcctaagaa aaagaacaaa
    11521 acatttctca tcagcaaatg aaaaatattt tgttcttttt atcagttgtt ctttttattt
    11581 tttatctctt aattatgttg ctctttccaa tacgacaatg cttttcattc ctctagatat
    11641 cgccgtgtac atttgtctgc gtcttctttg ctcatctcca tcgttttcaa atggatataa
    11701 gattacatga tcaaattcca gtccttttgc tagactcaaa ggaatgattt ggcagttttc
    11761 taatccatat gaattttttt taatcgattc ttgtagcgtt tgggtttcct cttctgtttg
    11821 ggtgataact gccgcttttt ctccttttag agaaaccaaa atctcagcta gtattttcaa
    11881 caattcttca gaggatcgaa aagagcggta ttcgggttct tttccttgcg gtcggatcga
    11941 tacgatgtcg atcttctctt gatccacagc ataggttttg aaaagctctg tgattgctcc
    12001 gctagaacgg taactatttc taagatcata ccgatggatc ggcagatggt agtcgtcgaa
    12061 acaacgcata atatcagcaa aagtagtgga agaattaaag attgcctgat tctcgtcacc
    12121 tactaaagta aagtgagttt ttggaaataa ttcgatcaat agacctaatt gtgccagggt
    12181 ataatcttgt acttcatcaa tcaatagata gcgaaatgct ggtacattta ccttttcaac
    12241 aagtaaatga cgaatagcta atataatgac tgcttcatca acagtacgtg tgggttgcca
    12301 agcataagct gagccatatc gtttttcata aattctttca aacaactgat gctcatccac
    12361 ccatgccatt tcttcgattt gtctggttat ttttcgatat tttttttgta aaagtttcct
    12421 tgcataagct acaatacttt gttccgaatc atcagaaatc aatttaccga ataattccaa
    12481 ctgcctatct tctgtcaacg agagtacctg attctgcaca gcaggacttt ttgcttgttt
    12541 caaaagatga ttcttccatt cgctcatcag tgcctttttc gttgcttgaa gcctatcgat
    12601 caatttagga tgagcaggaa ctttctcata tattttttcg atcgtttttt tagaaaggac
    12661 tgtttttcca tttttagtaa gtccacggat aaaattcgga tgatctaaaa acaaaggatc
    12721 tgattgtttt agattatcga taaacttttt gctacgcaaa cgttctgtct gctccgatac
    12781 attttctccc gtgatacgtt tgaaataagc ctcttcacct tctatttcct ctgctgaaag
    12841 ctgtgaaacc agctgtatga tggttagatt cagtggattt ctttcaccta atgatggtag
    12901 gacattcgaa atatagtcga taaaccgatg attaggtgat agaatcagca agtcatcgga
    12961 tgtcatcgta tctcgatata aatagagcag atacgcaata cgctgcatga tagcagaggt
    13021 tttaccactt cctgctacgc catttaccaa gatattttga cttttcacat cccgaatgat
    13081 tgtgttttgt tccgattgga tcgtagcagt gatagccttc atttcattgg tctcatcttg
    13141 gcctaagact tctaataata cgtcatcttg aatagctaca gacgtatcaa aaaacttgac
    13201 caaacgatct ctttccaaaa gaaattgtcg tctttcttta ataaccgtat cgattttatt
    13261 ttgacgaacc gtataagaag atggaccaat catgttattg taaaaaagtt cggcaattgg
    13321 tgaacgccaa tcataaacaa gattttcatc tgcatcatct gtgaaatttg ctgtaccgat
    13381 ataaaaggat tcttttggct cattatccag aaagtctaca acgacttttc caaagtaggg
    13441 acttttcaat aaacgttcga tctttgctag ctgattttct gcgtttttct gtttgatatt
    13501 catctgatcg atttctctat ttttcatttc aatcatcgaa aaagtatcca ggttatctaa
    13561 gtaactgtca aaattcaatc gaagctcgcc agccatttct ttcaacgact ggtttccttc
    13621 tatttttgcc gtatccatcg attcccgcag ttcgtttttt ttatcaatta gcttttgata
    13681 cacgttcttc agatatgctt cttctaactg tttttgtgtg ttgaccatac acattctcct
    13741 ctttttttaa agtggtggaa ccgattagtt tacctctttt aagagtcgaa tgcaagcttt
    13801 ttaacgagta tcatttgtta ggatatatca gttcttcagg tcggacagtt tgatataaag
    13861 aaaatgcacc atcaaggttt tttacgtggt agccagactg cttcaagatt ctttccgcta
    13921 gatagctacg taatccgcta tgacagctga cgatatattc ttgttggctg tctaattcat
    13981 ttaatcggtc ccgaagttca ttcaaaggga tatgtttggc ttccttgaat ttgccctttt
    14041 ccaattcttc tgctgttcgc acatctaata aaatttttcc ttttgctagt tctgtcggca
    14101 attcatgcca ttgtacggtt tcactaagcc cttctgcaat gttcattgct gcatatccta
    14161 gcatgtttac tggatctttg gctgagccaa atggcggtgc atacgtcaat tctaattccg
    14221 gtaaatcgaa gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg atccgtttat
    14281 ccacaccttt tgccccaaca ccttgtgcac cataaatctc gccagtctct ggatggaaga
    14341 tcaacttcag taaaatatct gttgcttctg gataatagct tgcatgatct tttcctgata
    14401 catgaatgac ttcaaaagac agttcgtttt ctttggctgt tctttcactt aaaccggtgg
    14461 atgcggcagt cattccaaac gttcgtataa ttgctgttcc aataccgcct tgatttcttc
    14521 gagaaattcc ggaaatcgtg tccgcaactt gtctaccttg acgattggct ggtgaagcaa
    14581 gagaaataag tgcatctttt ccagtgattt gctgttttac aacgatagca tcccccaccg
    14641 cataaatatc aggaatattc gtttgataac gttcgtctac taggataccc ccgcgtatgc
    14701 ctaattcgat tccagcggtc actgctagct ggttatcagg acgaacacca atggataaaa
    14761 taactaaatc agcagggatg gtacgcccat catccagtcg caatcgtttc ccgtggtctt
    14821 caaatccagc gacagcatga gaagtaatca cttctactcc ttgatgagac aattcttttt
    14881 ctataaaagc tgccatttct tcatccagtg ttggaagaat atgtggtgct tgttcgatca
    14941 ccatgacttc taaacctctt ctttttaggt tttctgccat ttccaatccg atgaatcctg
    15001 caccaacgat cacggcacgc tttggctgtt tttctaatgc atgcatcact ttatcgatat
    15061 ctggtacatt tctaatagaa aaaacattgt cggcttctgt tatccctgga atcgatggaa
    15121 caactggttt tgcaccagga gataaaacca atgcatcgta ctgttcaatg tgtttttgac
    15181 cctcatgtac gacttctacc gttttgtttt cgggaaagat ggctgtcact tcatgatttg
    15241 gacgcacatc taaacaaaaa cgagcggata atgattctgg cgtttggaca agaagatttt
    15301 cccgttcact gatttctccc gaaagataat aaggcaagcc gcaatttgca aaagaaacat
    15361 acggtccttt ttcaaaaaca acgatttctg catcttccat taatcggcga agccgtgtag
    15421 cagcagacat tccacctgct acacctccga caataacgat tttcatctta tttccctcct
    15481 actgttcgat caaaccattg attcatgcca ccacgtacat tcactacatc ataaccagat
    15541 ttctttaatt ctttagctgc ttgtttactc ctcatccctg attgacaaat cacatagacg
    15601 gtcttttctt tgtctccatc atatctgttt atactttgta atggaacatt tttagctcct
    15661 tttatatgcc cgccccggta ttctgcaggt gttctaacat caagtaacgc tggattttcc
    15721 aaaagctttt cctttaattc tgggactgtt atcgatttta ttgattgaaa tagcaaattc
    15781 attttctgca cctcatttac atttttataa atacctcatg gggtatatta aacaggagct
    15841 ttattaatat gtcaaccaga atgactcttc atttttttca ctacttttta tatttgcata
    15901 aaataccgat aaggggtatt atctaattat aaaaatagag gagaatgtgt tatggagatt
    15961 gataataaaa atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg tggtatccaa
    16021 aaaatgatcg aagacgaaaa agaatgtatg gatgtcatca ctcaattaag cgctgttcgt
    16081 tctagtattg atcgcgtaat gggcatgatc gttgcagata atctgaaaaa ttgctttgag
    16141 aaacctgata gtaatccaga agaacaagcg gctaaactag aacaagcgat caagatgatt
    16201 attaaaaagt aaaggaatga tttcaatgaa agtcgttttc catattgatg aattagaaaa
    16261 atggtcagaa acagggaaaa acgtaaaaaa cctgataaaa gcttctccag aaacgacgat
    16321 tgtcgtatct gtaaatggca tcgcgattac cggttatcta gactctgcca atgcagaatt
    16381 cttagatttg caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg ctaatcatat
    16441 ttcagaaagt tctttacctg aacaagtaat cgttgtacca gcaggtgtcc ttgatttagt
    16501 tgaactgcaa tcccaaggtt atgcttatat caagccttag tcagtagagg ttgcgacaga
    16561 agtgatcagc ttcaagaaat ttcggcttat ttttcgaaga agctacttct ggaaaaccgt
    16621 gaatcaaagg ttgtgaaaac gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat
    16681 agcttctcat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
    16741 gtttaaggaa gaggttgtga aatcagcggt ttgacctaag tattagagaa aaaaacggga
    16801 aaatagctcc tcatattttg ccgttttttg agctaatacc gaaggtcagc tgattgaaca
    16861 ccgtttaagg aagagattgt gaaaaagtcg cttagtttcg agtattaaga aaaattttgt
    16921 gaaaatggat ttctacattt ttgcataaat ttggcttaat accgagaaac tggcttttga
    16981 ataccgttta aggaagaggt tgtaaaatca gcggtttgac ctgagtatta gagaaacaaa
    17041 cggaaaaata gctgctcata ttttgccgtt ttttgagcta ataccgaagg tcagctgatt
    17101 gaacaccgtt taccaagagg ttgtgagcct accatttaac tccgaatcac aagaaataat
    17161 ttcaaaaaca acttctcctg tttttggttc ggttggctta ttatcgagaa gtagctactg
    17221 ggagtctatt tatcaaaaaa aggaatgcga cataggtcac accccttttt tattttcttt
    17281 gaaacatctt tcggtactcg acagcataca agacaaaaga ttgtaaaaga ccgtaagtga
    17341 tgacggcaaa aatgactctc acccacagcg ttggtaattc tgggaaaagc agcaaaagga
    17401 tcatgccaac atagatgaca gcagtcgcta ctttgccata ccacttcgct ccacttaatt
    17461 tgatattttt agatagcccg attaatccag ctacaaacat aaagccttct tttatcaaga
    17521 atagaccaaa caacagccaa agccacggtc gataccatgc catagacaaa atcagaaaaa
    17581 gttgtgtcaa tttatctgca aacggatcaa gcaccttccc taagtctgtt acctgattat
    17641 atctccgagc aatgaccccg tctagataat cagacaaacc tgagacaaca atgaccgctc
    17701 ctgctatata aaatgactgt ctcagcacaa aataaagata aatcggcagc aaaaaaatac
    17761 ggaatatcga taaaagattc ggaatcgttt gtatttcttt acgccagtct gtgcttaatt
    17821 tcattttatc gccctacctc ctcagcactc ttttcttttt attttagctt acacggggaa
    17881 taaaaccaat gatttcactg tttttatttt tctttacaga cactgatatt atgagctaat
    17941 ttgagataat cacttgctgt tttcatcgtt tactcttctt tcttcctgtc gtttgcgcat
    18001 ttcttttact agtactttat gagctttttt tgatcctcgc tctaggtcac gctgccgttt
    18061 acgtgtttta taatcgataa acagactgtc taaatcgtaa cctgtcgggt acagatcttc
    18121 tgctgaacgc accagacgaa cacgctgacg aggcacgtgg attatttttt tgtctaaata
    18181 tacatcaatc gtatcttcac ctatatcttc ataaactaac gcttcttttt ggtattcatt
    18241 gacaaatatc cgatcacctt ttgcaaagag ctgacgttct tttttattct ccttcctatt
    18301 tgtaactgct gtcttaggaa gaaattcttt tttctgtgtc cgataggctt tttccgccaa
    18361 gtaacgctct gcttgatgga tcaatttcat cgacatatcc attttatgag caatccacaa
    18421 agcttggctt tctcctgttt cttccaaccc gcaactgata tttaggacga agtgcttccc
    18481 gatcgaaagc catagcagcc ggcacaaaat cttcatgatc tccggcgaat ttcttgattt
    18541 ctccataatg ggtcgtggca atgatcaatg ccccttgctc atacatagat tccatgattg
    18601 cgatcgctag tgcagcccct tcatttggct ctgttccact gccaatctca tctaaaagta
    18661 ccaacgtatt cctttttatc tttttcaaaa tagcagcgat gttttgcata tgaccagaaa
    18721 atgtactcaa cgcattttct aaattttggt ggtcaccgac atcgacgaaa atctcatcaa
    18781 agacagcaag ctctgtccct tcttttgccg gaacttgcat accgaacatc gccatcaaag
    18841 tcaataaacc gactgtcttc aacacgactg ttttgcctcc ggcatttgct ccggtgataa
    18901 tcaagcctcg atagtcttta ccgatttcaa catccaatgg taccgcatgc tcaggtaaaa
    18961 atggatgtct gccttgcttg ataatgatat gttccgattt attgattcta ggtgtgcttc
    19021 cattgatttc tcggctaaat tttgcccgag caaagatgat atctaacacc gtgatcgttt
    19081 cgatcaataa atcgatcact tcttcgtttt ctgcgatagc accagtcaat gccgccagga
    19141 cttgatattc ttcactgatt tcttcagctt ttaacaactg atagtgttca ttcaatttag
    19201 aaatcacagt tggttcaata aaaaccgtcg ttcttttatt tgattcatcg ataatcgttc
    19261 catctatttt atttttatag ctggctttga taggaatcgt atagtattcg cctttttgaa
    19321 caatcattgc ttcttggatc atttctttgt ttttcggatg acgcaagaat ttcagtaatt
    19381 ttgactggat ttctttttcg attagttgta attgtttgcg tactttacgc aaattacgtg
    19441 acgcgtcgtc actgacttta ttatttttta ttttctggtc aatcaactct tctacattta
    19501 tcaaatcagg aagatgtttg ctataagcaa acaacaaggg tgtctggtat tgattcttat
    19561 caaaaaactt tgtgatcatc cgactgcttc taagaaaatc cgcatattcg atcaaatcgg
    19621 ttggctgcag aatcaaccct tttttgactt gttctgtcag tgcatcgatc ctcggcaacc
    19681 ccataaatgg aacatgctga ctgctttcta agatcaagcg tgcttctctt gtttcttctt
    19741 gacgatccaa gacagtttgt aggtttgtcg agaccgtcat atcgctgatt cgttttttgc
    19801 tatagtttcc aattgctctt gcttggattt cctttttgat ccgatcaaat tgtaattgac
    19861 taatcatttc gttgtccata ttctctcctt ttcttgaaga gatacctgtc ccaaaataaa
    19921 taagggccta gagataaata aaaggataga acacagctta aaaaagtcat gtcctatcct
    19981 tattagaata caaagatatt gttttcctga caggtaccgt ttcataagca caccaaataa
    20041 actttgttta ttggctattc gacttactga ttagatacca gctacactca caaaacatac
    20101 cccattcttc taggtcttat ttattttcca cttaactata gcaagacaca ttttggttgt
    20161 caaactttag tatgttttat agatttacac cattaatgaa tagacaccta ccgcgataat
    20221 tgctccgatc attggacctg cgattggtac ccatgaatat gcccaatctg aagttccttt
    20281 attagctatt ggcaataccg catgtgctaa tcgaggacca aagtcccgag cagggttgat
    20341 tgcatatcct gttggccctc ctaatgaaag accgatggct aagatcaatc cacctacagc
    20401 gaatacgttc gttccaggtg caaattcgtt ttgtccaaaa gctagcaacc caagaactaa
    20461 tacaaatgta ccaattaatt ctgtgatcac atttgctgga taattccgta tagcaggacc
    20521 tgttgcaaac gttcctaaaa tcgcgctttc atctttcgtt gcattccaat gtggcaaata
    20581 agaaagccaa acaagaatgg cccctgcaaa agctcctaaa acttgcgcaa tgatgaaagg
    20641 aacgacaaga ttccaactaa ttgcccctgt catcgccata gctagagaga ctgcaggatt
    20701 caaatgagct gggcccatga atccagaaat atagacagcc attgttacag cgagtcccca
    20761 accaaatgcg atgacaatcc agccagaagc ctgtgcttta cttttgttta aattcacagc
    20821 cgcacacaca ccatctccaa gcaaaactag gatcagtgtc ccaataaact cccccatgat
    20881 ttgagtcata tcactgttca tttatttctc cccctttagt tcccgcagat ctgattctgc
    20941 aatcaatgct tctaaacgtt tagtctgttg cgccttctcc tcttctgtcc attcaaaata
    21001 tccagcaatt gcatcgatca caggttgctt gatctcatca agctgatctc gttcaaacaa
    21061 cagatgattt gtacgacgaa tgagataatc gcctggggcc aaaaccattt cttcttctaa
    21121 accataacgt aaccgagctg actcagcgag actcaaacca ggataaggtg ccatttcttt
    21181 tgctaattca aagatacgtc gggcattagt cccgtaaaaa tcagcgatat aagtagcatc
    21241 ttcttcctct aaaccggctg ctactccttc ttttgctaat tctgtcactg tttcttctaa
    21301 tttagttgga tcgaagtttc cacctgaaat ctgatatttt ttagagtcga tttctttcgt
    21361 ctctattccg tattcttctt ttaataattg gcgtatcaat cgcaaagctc cttctgccat
    21421 cttacggtaa tcggtgattt tcccaccaga taaagtcagc aaaccatctg gttctctttc
    21481 taaagaacta cctctggaaa tcgtagaagg tgctttttca tcacggctgt tttccaaatg
    21541 gttcaacacg tcttctactt cagcacgaga aactttgttt tccttatatt cacttactgt
    21601 atcgacaact ttattgaagc tcttgtctga aatcgatcca ttatctccac cattgtaatc
    21661 agaaccagaa ttaccaatca acagtggacg aagtcctgcc cagcttgctt cgatatcatt
    21721 caatgtgata tttgcttctg gatagcgatg attgatcaca tccaatagat aatctacatc
    21781 ttcttgtgtg actttcggat ccgtaaaatc tccttggtaa tccgtatctg tcgtaccaaa
    21841 gtaagtcttg ttttctcttg gaatagcaaa aaccatccgc ccatcttgct ttcctgtatc
    21901 gaagtatgtg ggttgcggta caggcagttt tttcgcatct acaactaaat ggatcccttt
    21961 agttggacgc attttaggag agactggacg cgtaaaattc aagtttcgta ctttatctac
    22021 ccaaggacca ctcgtattga tcactaattt tgctttgatt tcgatcactt catctgtcag
    22081 caggtcacga gctttgacgc caacgatttg atcgccatca tataaaaagc caaccgcttt
    22141 cattttactt actagataag ccccatcttc ggcagccttt ttgatattat caatcactaa
    22201 acgggcatca ttgttgcgga aatctagata gacacccgcg ccttttagcc cttctttttt
    22261 caaaaacggt tctctttcca atacttcttc tggtgtcagc gtataattct catatttggt
    22321 tcctgtcaca tttgccagtt tgtcataaag gtccattgct actttgaccg agaacatatt
    22381 gaaggttgtt gctccttcgc cctcatagat tggcaaaagc attggatctg gttttgggat
    22441 gtgtggggca atactttgta cgactgcacg ttcaccaact gtgtcagcta ctacttccac
    22501 atcaaatgtc ttcagataac gaataccgcc atgaacaagt ttggtcgagc gagaggaagt
    22561 cccttctgca aaatcctgca tttcgatcaa tcctgttttg attcctgatg ctgctgactg
    22621 gactgccaca ccggcaccag tgattccgcc accgatgatc aacagatcca attcttcttg
    22681 ctgcattttt tgaatgctat cttgtcttgt cttgtttgaa aacatatgga tttcctcctt
    22741 attcaaatgc ttgggtagct tttactgctt ttttccaacc gttgtaaagt ttttctcggc
    22801 gctcttcctc catttgaact tcaaatagct tgccagcttc ataaaattcg cggatctcgt
    22861 ctgtatcttt ccaataaccg acagctaatc ctgctaaaaa tgctgcccct agcgccgttg
    22921 tttccaagtt ttctgctcgt tggatcggta cattcaagat atctgtttgg aattgcatca
    22981 gatattcatt gtttgctgca ccgccatcta ctttcaatac aggaatcttg attccagtgt
    23041 catcttgcat cgtatcgatg atatctctca cttgataagc aatcgactgt aaagtagctt
    23101 taatgatatc ttcttttgtc gtaccacgtg tcaagccaaa catagcccct cgtgctgcct
    23161 gatcccaata aggagcacct agcccaacga atgcaggaac aacataaacc tcatcttcgc
    23221 ttgtagagcg tttcgctgcg tcttctgaat cgctagcttt ttgcaacatt tgaagtccat
    23281 ctctcagcca ttgaatcgaa gaaccagcca caaaaatact tccttctaaa gcatagtaaa
    23341 cctttccatt tatgccgtaa ccaattgtcg tcaataaatt atttttggat aattgcggtt
    23401 tttcaccggt attcatgaca ataaatgaac ctgtaccata agtattcttg accatgcctg
    23461 gttcgaatgc catttgtccg aataatgcgg cttgctggtc tcctgccatc cctgaaattg
    23521 gtgcttcgct tccataaaaa tgataacctt gcgtataacc ataaacttct gagttagaag
    23581 tgacttttgg taacatcact cgaggaatat ttagtaaatc taaaatctcc tgatcccaat
    23641 ctagctgatg gatattgaac aacatcgtcc gactggcatt cgagtaatca gtaacatgtg
    23701 cttgtccatc ggtcagtttc catactaacc aagaatcgat cgttccaaac atcaattcgc
    23761 ctttttcagc tcgttcttgc gcgccttcta catgatcaag aatccagcgt atcttcgttg
    23821 ctgagaaata ggcatcgatc actaaccctg ttttttcgtg gaaaaattct tgatagcctt
    23881 cattttttaa gttatctgca attccagctg actgtctgga ttgccaaaca actgcatgat
    23941 agattggacg tcctgtatct ttttcccata ttactgttgt ttcacgctgg ttcgttatgc
    24001 caatcccagc aatctgattt ggtttgatcc ctgattcgat gaacgctccg gcaataactg
    24061 actgtacaga attccagatt tcatttgcat catgttccac ccaactttct tgcgggaaat
    24121 attgcgtgaa ctctttttga gaactgccga tgtgtcttcc tttcttgtca aagataattg
    24181 ctcgtgagct agttgtacct tggtcaatcg ccatgatata cgttgattct gtcattgtga
    24241 ttccctccat tatatgcaaa cgctttcttt aactactctt atcatactac tgttttaaaa
    24301 aaagaaactg tcaaaatttt attctttttt tctttttttg acagtttttt attatgaagc
    24361 tattttttaa tcaattcttt tcttttttca gcgtctctat tcttcttttc aatcgaataa
    24421 tgtcgtaagg tgacgcaaat tctgacagat aatattcaca ctgttttttg tttctctggc
    24481 aaaatgtgat caccaaatca tattctttac cttcttcata acttccaatc tcaataccgc
    24541 cgattcccct cagttctctg atcagatatt gttgaaaagc aatacgataa atcggcagac
    24601 tttctaaatc gattccaatc actactggtt ttgcaatata aaaatcgatc atcaaaagaa
    24661 cattggcata ctggatcatc aggtaactaa gctcactatc ttcagctctt ttcctcggca
    24721 attgctgcac cgctgtttcc tgtaatttcg ccagtaactg tgttaaggaa tgcccgagca
    24781 ttttctgctg ctgttccaaa agccgatcac gctcatagac ttcgatcttt ccaacaaaga
    24841 aaaaccattc attgttgatc tgggaaattt ggtagcctac tgccttttct tctttgattt
    24901 tcaaacgacg aggacgataa tgccataaca tcgtttcccg aatgtaagta tctaaaacag
    24961 cggttggtaa ctttttgctc cgtgtcaaat catactgata aaatatttct tcgtctacta
    25021 tcgaaaaaga aacaaaaaag ctgtaaaaca tcattgtttc gtatacattc agttctgctg
    25081 ctgttcgact aagatgcatc acgatgattg gatcgattgc ttgataaagc cggtccgact
    25141 gatagagtaa tttcttttct ttcaaagttg cgtacgtact tttttcattc aatagtcttt
    25201 ttttcgtaat cccgagccag caagcaatct gtgcttctgc tgatgccgta aacgttgttt
    25261 ctaatacacg gtccaatcct agaatgaacg gtcttttttc tggtgtattt tgcaaaaaaa
    25321 gcggtcgctg atcttccggg atatattgga atagttcata ataaaaatat cgtatctgta
    25381 gctcttctcc gtataattga ccgtttttga tttgtaatcc aaattcctct aagagctggt
    25441 tcaattcttt gatctttcga aaaacagaag actcactgat attaaacgct gtcgctaatc
    25501 gaacgatgga tacttgctga tgttctaata aatagacgag catcttaaac ttcaagcttt
    25561 cctgcaataa aaacaataga attttttcca aacttacatc ttcgtccaac acaagcagcg
    25621 cctgatactc atttcgctgt acttctactt ttttttccat cattcggcca atcaattcaa
    25681 tatcttccaa atattgatca aacgaggctt ttgacagttg gacatgctct ctcaaaccat
    25741 tgatagaggc tgttccccct tgcagaacaa ggtttcgcaa aatcaggatc tgtaactgct
    25801 cttttctttc taataatgct tcaatcttca taggcagtat tcgccacctt tgaccacacc
    25861 atatctggca cacggtattc tggctggaaa aatagctcat gttcttctaa ctgttcaaac
    25921 gtccatcctt cttctactgc aattgtcagt tggtcaagaa ggtggaacat ctcttttttg
    25981 ctttggagct gtgctccaag aatctttttt tcagaatcaa atagaaattt gagtttaact
    26041 ttgctttgat ttattgctgt aagcttgtag tctacgtatc ctgtttcaat tttttgggga
    26101 taaaaaatgc tctcttcttc tgtcaaacct acgcttccta agaaatagcc aaaccactga
    26161 ttgccgactg gacgataggt tccctgatcc tttgtctgtg agccactaat tgtcttgctg
    26221 acatttcgtg ctgtacggac agcgttattt actagagaaa catacatttt ttcatttgtt
    26281 ggacgaaaag ttacttggat cgcatcgcca atcgcataaa cgtctttttg agacgtttgc
    26341 aagtagtcat ctacccagat cgttccatca tcattcaatg ttaattgttc ttcccacatc
    26401 tgattgtcgg gacgagaatg attagccagc aaaacaagat catagttctc ctttcttttt
    26461 tccgtctcta caatagcggt ttcattttcg gtcaaagaca caacttgttc ttctaaaaaa
    26521 agtgaaagcc cttgattttt catttccttt actaacggtt ctgtcatttc aggatctaga
    26581 taacgaaaaa gaattgactt tcggctttcg taaagatgga tttgtttttt tcttgatgcc
    26641 aacccttcag ctatttcgat tcctgcttgt cctgcaccaa taattgcaat tttctttgca
    26701 ttcatgatct tttgctgaag agccgttacg ttttgtatct ttttaactgg gtgaataagc
    26761 gttgattctg cagaaatatt tcgaaacttt tgatttgaac cagtcgctag aatcaaacga
    26821 tcaaaatcca atttttttcc tcctgctaaa acgacttttt tttctttcaa tcctattact
    26881 gtcttttctg tgtaaacatg gattcgatag cggtcagtca gttcttcttt cgtgatccaa
    26941 gaaagttgtt tttcactggt aacctttcct tttaatatca aattgaaccc gctgggaatc
    27001 catcctaact tcgattgctt ttcaatcaaa tatatttcac ttgttggcat caattggcga
    27061 agataaatag ccgcatgaat ccctgcaaac gacccgccga caattacaat gttcatctgc
    27121 attcctcttt cttataaggt gttctactgc taacttctca atcagaaaac acagtattca
    27181 taactcgctt tcaaccttat gatacatagc gatgcagcag aatcaaccct ctccatcata
    27241 ccgtgttcta ggtctgcttc tcaataatgt actagtggac ctaattgaag agtatcattt
    27301 ctgaagagat gtttcaaaaa atgtactctt ataaaagaaa aaaactcgcc ttttacgtac
    27361 ctctgtccaa ataggaaaca gaaaagaacg aaaagacgag ttttagcgtg tgtaatgtaa
    27421 tagttagaat agacacatca tttattttta attctttaat gcttcaacaa ctgcttcgcc
    27481 taattgatga gcagattgag gattttgccc tgtaagaagc cgcccatcaa tttgaaccac
    27541 ttctgaaaaa gctgctccag actgatagtt tgctcctttt tctttcaaag catcttctgc
    27601 taagaatggt acttcattcg ttgtaccatt tgcttcctct tcttcattac tgaacccagt
    27661 cactgtacgt ccagctaaaa tagattttcc agactcatct gtaactggca acaatcctac
    27721 aacaccgtga caaacagctg agaccagccc ttcatttcga tagatttgtg aagcgacttt
    27781 cccaagatct attgcttctg gaaaatccca cattgttccg tggccaccag cataataaac
    27841 cgctgcataa tcatttgcat ccacatcatc aggacgtaag gtatttccca aggcccgatt
    27901 tctgaaatct tcatcttcat aataggccca atcgatttca tccatattca aaacactttg
    27961 cggttctaaa ggtacatatc cgcctttagg actgacaaaa tctgcatcga tcccattttt
    28021 tactaataca tcataaaaat gagtcagttc acttaaccac aaacctgtag gacgctcgat
    28081 cttttcgtac ttttctacat ttgttaatac gatcaatact ttcattttcc catcctcttt
    28141 ctataaaaat tgcgttattg ataacgtgct ttcaagaaat tatataatgg gcttggcaaa
    28201 taaagctctt tatatgcttt ttcaaaaggt ttcgttacaa attcatcctc acggttttcc
    28261 aataatttct ctgcccagtc aggatcgacg atcatttgct gtccaattgc tgcaagttct
    28321 gcatatttca atacctgctc tacatcttcg cgattgcgga tcccaccgac accaactaaa
    28381 gggatctttc cttgaatcgt gttatggacc acttcaagaa tcgatttatc gttgtattta
    28441 tcagaacgag ctattcgatc atacatattt aatgaaacat gcagataatc tagttttgac
    28501 tcacgtaatc gttcaagaag ccagatcgtg tcttcaaaac ggatacctgg tgtttcatat
    28561 tcttctggtg agaaacgata ccctacgatg aatggttttt tagcatattg ttcaaccgct
    28621 gagaaaaccg ttgttaataa ttcttcaata aaacgataac gattttccaa gctaccgccc
    28681 cattgatcct ctcgtctatt cgaatgcgga gagaaaaatt gttggatcaa atacgtattt
    28741 gctccatgca actcgattcc atcaaatcct gattcaatcg ctctacgtgt ggctttgcca
    28801 aatgcttgga ttgtttcaac gatttcttct tcactcattg ctcgtggtgt ttccgcatca
    28861 ggacgttttg ctgcaactgc acttgcagat acaggctgtt ctccagataa agttgctcga
    28921 cttgtcattc gtccaccgtg gaaaatctga ataatcgctt ttgcgccttc tccttggatt
    28981 gctttcgcta gctcacttaa tcgaggaatc atttcatcat gagcgatgct gagttcacct
    29041 ggccagcctt ttccgatatc ttggacattt gcagcaccag taataacagc accaagacct
    29101 ttagaacgtt gtttataata agtgatctca tcttcggtga tcactccatt gaaaaagctg
    29161 agttgtgtcg tcataggcga cagcatcaat cggttcttca attgaactcc tgaaggtaaa
    29221 gtaattgatt gatcaaattg tgacattgtc attcctccca taattcgctc tgattaacct
    29281 atcgagaatc atctatcatt aaaccactcg attagttgta catgcaacta atttgcttaa
    29341 aaaattttat tttttttgta acttatctgt tgcatcattc attgtctggg ctaattcttt
    29401 acttgcttca tttcccaaaa ctgctttgta tgactgatga agttcttccc agctaccatc
    29461 gacttcctta gcaaattggc gtccttgttc tgtaagataa actaatgaca agcgaccttc
    29521 gctaactgtt ttgacgtatc ctttatattc taatttttca acaaaacgag caatcgttga
    29581 tggggcggaa tagagcattt gtgcaatatc tttttgtggt attccatctt tttcttttaa
    29641 tatcaataaa ataaaaccat aagttggtgc cagacctgtc cttctaaacg cttcatcagc
    29701 taatttattc aacatgcgat ctagcttttt cacgctaaag aaaagacatt catctaacgc
    29761 tttttcaatt ggcttttcca tttcatcccc tccattggcg tacatatcat agtatgattt
    29821 ttattttttg tcaaaaaaca cggaataatg tccgcctcct ctgtctagat ttgaaaaaaa
    29881 gaagtagcca tcttcaaaga atttcggctt gttttcgaca aaactccttc tggaacaccg
    29941 tgaatcagag gttgtgaaaa agtcgtttag ttttgagtat gaagaaaaat tttgtgaaaa
    30001 tggctttcca catttttgca taaatttggc ttaataccga aaaactggct tttgaacacc
    30061 gtttatatca gaggttgtga aaaagccgtc ctgcatcaag taataagaac agccaaacaa
    30121 aaatagttcc tcatattttg tcgttttttg agctaatgcc gatggtcagc tgattgtaca
    30181 ccgtttattg agaggtcgtg agcctgccgt tgaactccga gtcacaagga gcaatttcaa
    30241 aaaacagctt ctcatgtttt atgactatgg tgacttgtga tcgaggagtt ggcaggagaa
    30301 tactgtttat tcgtaaagaa ggggctgtga caagactttt gtcacagtcc cttatttcct
    30361 tttattatag gatttcgcca tttgattgga tgacttgtct gtaccaatca aatgattttt
    30421 tctttaaccg tttctttgtg ccattccctt cgtcatcttg atcaacatag atatatccat
    30481 aacgttttga catttgtgaa gtagaagcgc tgacgatatc aatgcagccc cacgacgtat
    30541 aaccaaataa atctactcca tctttgatag cttccttcat ctgctcaata tgctgcttca
    30601 aatagtcaat gcggtaatcg tcttgaacgg ttccatcttc ttctactttg tctatagctc
    30661 cgagtccgtt ttcagctatg aacagtggtt tttgatacct atcatataat tgattcaaag
    30721 caattctcaa acccttagga tcaatctgcc agccccattc acttgatgga agatacggat
    30781 ttttaattcc tccagttatt aagtttcctt ggaccccttc ccaattttct ggatgagcac
    30841 tgactgcact agacatgtag tagctaaaag aaacaaaatc aacagggtag gctgctaaga
    30901 tttcttcatc acctacttct atttttaagt tgacaccttt ttcttcaaac attcgttgcg
    30961 tatacgctgg ataatatcct cttgcttgaa catcactaaa gaacaaagaa gttctttgct
    31021 gctcaattgt tttttgaata tcatccggat cacaagaata cggaacaaga agctgatagc
    31081 tgatcataca accgacttgt gaacctttga taatttcatg acaagctttt gtagctaaag
    31141 cacttgctat aaactgatgg tgtgcacctt ggtatttcgc ttgttccaaa tggggatggt
    31201 tttcttcaat tactcctacg ctaacaaaag ggtgatgttt tacacagttg atctcattga
    31261 aagtcatcca atattttact ttatttttat agcgtttgaa tactgtttca gcgaaacgaa
    31321 cgtaaaactg aataagcttt cgattaggcc atccaccata ttctgtaacc aaatataacg
    31381 gcatttcata atgggaaaga gaaacgactg gctcaatccc atattttaga cattcgtcaa
    31441 acacttgatc ataaaaaaat aatcccgctt cattgggtgt ttcttcatca ccatgaggaa
    31501 aaattcttgt ccatgcgata gacatccgat agcatttaaa acccatttca gcaaataaac
    31561 ggatgtcttc tttaaagtga tgatagaaat catttccgtg tcttttagga taataatact
    31621 tgctgttggg atcctgcgcc gcttttactt gctgatgcgt catcatatgc cattgatctg
    31681 tccatttttc tttaggtaaa tcgctgtcga atgtatacac atcagacaca gataatcctt
    31741 tttcatctac atcccatgca ccttcacatt gattggccgc tgtcgctccg ccccataaaa
    31801 atccttctgg aaattttttc atatcgatcc ccctaaactt gctagttttc ttgtttgatt
    31861 atttttctta tgactagtaa tgatattttt gaatctacta ctatttgtaa caataaccat
    31921 tgtggtcgga tcatatccct ctttgattaa ttcttgcaaa tctacttcca tcaataaatc
    31981 gcctttacgt actttttttc catcagatac tgcactttga aagtatttgc catttaaatt
    32041 cactgtatca ataccgatat ggatcagtat ctctgctcct tcttcactga ctaccccaat
    32101 tgcatgtttc gttggaaaaa ctgttgaaac ttccccgttt acagaactgt agatttttcc
    32161 gtccgttgga atgatcgcaa acccttctcc taaagatcca ctagcaaatg ttggatcgtt
    32221 tacttcagat aaatcaatta tttcacctgc tgcaggagta cttaacacta tatcctttga
    32281 ggattcttct tcgatttcat ccttgtagcc gaaaagaaaa gttagcatac aggaactgat
    32341 catcgctaag aaataactag caactagcca aacaaatcct tcaccaatat aaatcgggaa
    32401 agacaaaata cttcttgtag caactgccaa agcaccggct cctgcggcac cagctactcc
    32461 accaaatata gctccacata tacaagcaat gtaaaatggt cgtttatatt taagagtcac
    32521 accataaaca gcaggttcag tgattccaaa taatgctgtg ataaatgcag ataaagataa
    32581 actttttact ttcttatttt tcgttttcaa aaatacccca agtactgctc ctgcttgcgc
    32641 agctacggca gtcatacatg ctggacctag cgtatcacga ccgtagaaag aaagattgtt
    32701 ggtcattact ggtacaagtc cccaatgtaa cccaaaaatc actaacactt gccaaaatcc
    32761 gccgataaca gcaccagata aaacagggct aaagttataa acagctaaat atccagctgc
    32821 aatcagctga cttgcataat ctgcaattgg acctacaact aataaaataa ttgggaccat
    32881 cacgatgata caaatgaatg gtgtcaataa atttcgaata ctttcgtgca agcttttgcg
    32941 aatcttaggc tcaatataag aaagaaccca tacagctaaa attgctggaa taaccgtact
    33001 tgtatacctt gctagaatca cgggcatccc tagaaatcgc aaggttatgc tatcactata
    33061 tgcactgaca atcgtaggat aaacgagagc tgctgcaata accatagcga tgaaacgatc
    33121 tgtattgaac ttttttgcag cagtatatgc caaaaatata ggcaagaaat agaaaaatgc
    33181 atcagctgct gcattcaaaa tgatataagt tcctgattca gtagttaata aattcaaact
    33241 cgtacataag gcgagtactc ctttgatcaa accacttcct gccaagacgc ctaaagtcgg
    33301 ggcaaaaaca gcggcgatca tgtctataaa agagtttaaa atgccttttt tctcagttcc
    33361 tctctttcca ctagatgcat catcttctag tttcatttgt ttggataata cgtcatacac
    33421 ttcatttact gcatttccta ctacgacttg aaacattcct ccagcttcga ctacagtgat
    33481 cacaccttct agttgctcta ccttctcctt atctgccttc ttattatctt ttagggtaaa
    33541 gcgtaacctt gttgcacaat ggtaaacatt gctgacattt tcttcgcctc cgacaaatcg
    33601 gacaatatct ttcgctaatt gtgaatagtc catttttact tcccccttgt taattaatgc
    33661 cgtagcaatc cttcttacaa gataagtata gttcttagaa aacggtttct ccattcaatt
    33721 agtacccctt ctaatagcga acgaaactgt acaatagtgt gtatggttta cttagccgag
    33781 caaatcactc actgcttgaa agaaaacaag tatatcgttt ctcttatagt caaaggagac
    33841 aaaaaaaaca cgcttgatct tcctttgctg atgtataagt ggtatctcaa gctgatactc
    33901 tgtgattttt gtttctactt ggcttttgat aagacagcac aacaaagtct cggcatttaa
    33961 cggaagcata actaggtcag aactaggaga gattagttgc tgaatggaat ctatcttttt
    34021 atggattttt atttgatttt cttctttgta gtaatgatca agcagttttg ttttcttttt
    34081 ttcttcaact atggtcagct tttcacgcaa aatctgataa atctcccaag attcaaactc
    34141 atctagaaca ctaggtagat aaatcaaatc atcccactca aaaataagct cttgctcagt
    34201 agtcaaaatt gcatcatatt ccgttatttt gtttgattga tttttgaaaa gatacactgg
    34261 ttctatccgg cattctttga tccacatgtt catactttgt tgaatctgtt tttttagtgt
    34321 attcaaaata ctaattggct ggttactaac aatcagtatc tccccttgtt ttcgaaaagg
    34381 attcaacgct tcggcaagat acaaaacaaa ataagcgctt tcagctaaat tgggacgtaa
    34441 ttgaaaatgt attgggaaga aacgccgaat taaataaatt tctaaaggat aacgggagat
    34501 gatcttttgt acaaaatgat tcatggtatt atgtccggca tccatcctcg ttttcatttg
    34561 tttgatatgg gttagcaaaa attctgtttc atggaacaat aacgaaacag gaagatctaa
    34621 aaaacgaata atcgtttgct caaatgctct tagattcttc tctatttctt tgtttttttc
    34681 atcattaatc atcaaataat ttaactctaa tagtcgattt tcaattgctt gtttttcttg
    34741 attggaaaaa gaatagggta gttctgatga taactttttt gtgagggtct ctaccatcgg
    34801 aataaataat gtatacctgt ttgttttttc taaaagttct tctcttcgaa gaatggtcaa
    34861 aacgagatac cgagaaaatc gtatgaagtc ctctcctgaa acaatataat tatatgatat
    34921 aagaacctct tttaatgtct tttggacagt cggcatgata ttggaaaaaa ttgtactgat
    34981 ttgttgagga aaccttgcgt gttggatcac cgtttctgtt ccaacaagag ataagaaaat
    35041 tctttttgaa ttttcttcag caatgatttt tagtcctttt gtcgacgaaa cttccagttc
    35101 taatttagga ttgcgctcga tccaacgcaa aatcgttttt atttgtaatg atacggctgt
    35161 ttttgaaaga aagaaaatgt ctgctatctt ttgcatactg acataccctt tttgaaacaa
    35221 taagtacgtc acaatagttg aagctcggaa atccatgctg gaatagattt tatgtttcgt
    35281 cacctcttgt atgatttgct gtttagtttc agattcaatt gattctaaaa aataacctga
    35341 acgtttattt gactggataa tgattttctt ctcgtagata gcaagcatat ttttgatttc
    35401 agtttggatc gttttcttgt tggtacctaa agcttcagct aattcttcgc ttgttatcca
    35461 atgattctta tttcttaata ctacaagaat ttggagttgt cgtttattta agtccatttg
    35521 cttacacctc ctctttgtta taaacataca ggaaaaacct ctcaaatgac aatagtcact
    35581 tgcagaggtt taaaaatcat ttgaagaaag atctatattc aaggttttta ccattagact
    35641 ggataatttg tttataatat tcaaaactat cttttttcaa tctcctaaag cttccgctcc
    35701 catcattttg tctatccaca taaataaagc catatcgctt cctcatttcc cctgttcctg
    35761 ccgatacgat atcgattggt ccccaccata agtaaccaat gatttggcaa ccatctttta
    35821 ttgcctcagc aatttcctga agatgtattt ttagatactc acaacgtttt ggatcgtgga
    35881 ttcgattcaa ttcatctggt gcttcatcta gtccaatgcc attttcaact atgaataatg
    35941 gtaattcata acggtctgtc aattcattca tgacataacg aaaccctaga ggatcaattg
    36001 gccaactcca aggttcggga gatttttcct tcaaaaaggg attatcgaaa ccatttgctc
    36061 cgccagtatc tacgcgcatt tctgcttctt ttttatagac agcgctacga taataactaa
    36121 atgcaatata atctgccgtg ttagcttgca agcactgttc gtctccatct aacattactg
    36181 gtgcacagtc ttcttccttc catgtcctgt aaatataagc tggataatgc cctcggcaca
    36241 tgacatcgga gaaaaaccat gaattgcgtt taaattgcag tgaaccaaat acattctctg
    36301 gatcacagtc atatgcataa gtcgctaatg cagaaaagct acacataata cccatcttag
    36361 catttggatc gattttcttt aataattgag tagcacgggc gttcgctaga aacatatgat
    36421 gacaggcttg ataaatcact ttttttgtta gtgtagcaat gggttcaagt ttatctctag
    36481 cagggaatgt aaccaatcca gcagctgcat aaggcatacg aaaagcatta ttgatctcat
    36541 taaaggtcat ccaatatttc actttccctt ggtagcgttc aaagacggtc tgcgcataaa
    36601 attcaaaaaa gtcgattaat tttcgatttt gccacccccc atactctcct accaatgcta
    36661 agggggtttc ataatgacta agagtaatta ctggctcgat atcatatcga tttaatgtat
    36721 tgattagtct gtcataaaat acgagaccag cctcatttgg cttctgttcg tctcctcttg
    36781 gaaatattcg tgcccatgag atgcttgttc gaaaagcttt taaacctaac tccttcagta
    36841 aacgaatatc ctcttcaaat cgatgataaa aatcaatcgc ttcatgagaa agataatgga
    36901 gtgattcgtc taaagcaatc tcccaaatct ttttttcttc attccactga atactaggat
    36961 gctggttcat gatcccgata agcgtatctg tcacattagg taatttgccg tcttccaacc
    37021 atgcaccttc acattgatta gcagctactg ctccgcccca taaaaaattt tctggaaata
    37081 tttcctgatc cataactatc tctcctcgct atcaacaatt tcttacttga agtatagctc
    37141 gattcatcaa aacaagatat tctaactatt tcggcagaag agaagaaaaa aattgaatgc
    37201 tactcttcat ttttaatatt tatatataac aaatacataa gacgatcccc gaaagaaaac
    37261 actcgttaac catctaagca aacgatttat tttacttcca acacaaatgc ttcataaggt
    37321 cgtaaatcaa ctttgccgtc tggtaactgt ttcagaggat aatttgacac aataaccctt
    37381 aaagcttcac gtggaatagt gaacgtctgc ttttcactgg acatattaca aataacgagc
    37441 cattgctggt cttcatatat gcgagaatag gcaaagacat gctcaggcgt cttttccact
    37501 aattcatagt ctccccagac gatgatgtca tgttttctac gcaaatcgat caatttcttg
    37561 tacatataaa aaacagaatc ttgatctgct aacgcttctt ctgcattgat ttctttataa
    37621 tttggattga ctcgaagcca tggaattcca gtagtaaacc cagcatgttc acgggcgttc
    37681 cattgcatag gcgtcctagc attgtctctt cctttcgcct tgattgattc caagatttcc
    37741 tcttttgtaa atccagaaga aatcctttcg ttatacatat tgattgtctc aatatctttt
    37801 gcttccgcga tatcatcgat tgggcaattc gtcatgccta actcttctcc ttgatagata
    37861 taaggggtgc ctttcatcat atggagcaag atagcaaaca tcttggcact ttcttttcga
    37921 tacacatcgt catttcccca acgagaaaca attcgcggaa gatcgtgatt attccaaaat
    37981 aaactattcc atccttcatc acctaaagat gtttgccatt tggataatac ttttttcagt
    38041 tcagagatac tcaagggttt caaatcccat ttgtctttgc cttcttgctg atctaatcct
    38101 atgtgttcga attggaagac catggataat tcatttcttt taggattgga ataaagttta
    38161 gcgatttcgg tagttgctcc ccatgtttcg ccaacagtca tcagattttt gtcaccaaaa
    38221 gttgcttgat tcatttcctg aagatactca tgcagtttag gtccattact tgtgatttct
    38281 ttatccggtt ctttgccaat catatcgatc acgtccatac gaaagccccc aataccttta
    38341 tcgatccaga aattcatcat ttgataaatc tcttggcgaa cctgtttatt tttccaattc
    38401 aaatcaggtt gacgcttgct atacaagtgc agaaaatatt gccccgtttt ttcatccaac
    38461 tgccaagcag aaccactgaa tattgagcgc aatctattag gctcttttcc attgaccgga
    38521 tcacgccaaa tataatagtc ccgataagga ttttctttat ttttacgggc ctcaatgaac
    38581 cacggatgtt catcagaagt atgattcacc accagatcca tgatgatacg gatatttctt
    38641 ttctttgctt cttcaatcag ttcttccatt tcttccatcg taccgaattc tgccatgatt
    38701 gcttgataat tactgatatc atacccattg tcatcattcg gagactcgta tactggagaa
    38761 agccaaattg catcaatacc taaatacgcc agataatcca acctggaaat aatcccccgc
    38821 aaatctccaa taccatcttg atttgaatct tgaaaacttc ttggatagat ttgataaaca
    38881 actgaatggt gccaccattt ttgttccatg attttcctcc tataaatgga tgtttctatt
    38941 ttttgcttaa tcatttattt tagtctctct cactaaaaat tgtaacgctt tcaaatagct
    39001 attgcacctt gttatcggta acagaataaa acaaaaaaac agctgaggaa attccctcaa
    39061 ctgttttttg aaaggattga tttatgcagg gaagaatgct gatttcacaa cttctttata
    39121 aacggtgttc actcagctgt cccttggtat tagctcaaaa aacggcaaaa tataagaaac
    39181 tattttttcg tttttttctc taatactcag gccagaacgc tgatttcaca acctctttat
    39241 ttcacattca atatccacat gaatcccaca aatacaaaga acagaccata catgattgga
    39301 gatacttctt ttcctctttt agctgctaac atggtaattg gatagaagat aaaacctaat
    39361 gcaatcccat ctgaaatact ataagtcaaa ggcatgccga tcaagatcaa gaatgaaggg
    39421 atcgcaatct ctaagtttcc ccattcgatt tgtcgcaaag attgtgccat caatactcct
    39481 accataatca atgctggtgc agttacttgt gaagtaacaa ctgatagtaa tggagaaaag
    39541 aacaagccta acaagaagaa aatccctgta gtaatagctg tgatacctga acgtcctcca
    39601 acggcgatac cagctgatga ttctacaaat gcaccaacag gagaagtacc aaataaggaa
    39661 cccgcaagca tagctgttga atcagaagct aaagctttcc ctacacgagg catcttgttg
    39721 tctttcatga aacctgcttg gtttgctaat ccaactaaag ttcctgctgt atcaaagaaa
    39781 gtcacaagca agaatgtcag cactacgacc cacatttgaa gagaattgat gtcccctaca
    39841 tgttttaatg caactaaaaa tgttggtttc aaacttggtg ctgcggcaac aatttcagaa
    39901 ggcattggaa tcaaacctgt gaccagacct aaaatcgttg tagctgccat cccgatgaag
    39961 atgccacctg gtacacgccg aacaagcaag atagcagtta cgactaatcc aaaaatcgtc
    40021 aaccaagtag aaccaacgtt gagtgatcct aatcctacta atgtagattc attcgaaacg
    40081 atgatcccac cttcgctcag accaaggaaa gcgataaata gaccgatacc gccagaaatc
    40141 gcatatttca aatctgctgg gatcgcatca atgatcattt cccgcagctt gaagattgtg
    40201 atcaaaataa aaatcaaaga agcaacgaat acgccggcta atgctgtttc ccatggaatc
    40261 cccattccta aacaaacaga ataagcaaaa aaagcattga tcccaagagc aggtgccgtt
    40321 ccaattggat aacgggctaa tacccccatt aaaacacagc cgatcgcact ggctaatgca
    40381 gtcgcagtaa acactgctcc ttcatccatt ccagaagcac ctaatacagt tggatttaca
    40441 aataagatat aagccattga gataaatgtt gtaaatcctg ccagtacctc acgttttacc
    40501 gtggtgttca atttttctat ttcgaagtag gaaagtattt tttccttcat cttccatccc
    40561 cctaaatccg aacattataa ataaagtccg ttaaaatttc gatttattaa taaaacaacg
    40621 tgttttatca tatactaaaa caaaacataa gtaaacaaaa aattcggatt ttaagcaaaa
    40681 tccgaacgtt ccatctgatt aaatcccttt atctcaaagt tcatgaacat tcactttgga
    40741 ttacaagaat ttctttattg tgttaataaa gtttcttcat tctagtctca aaaatcaata
    40801 gtgtgatttg attttaccat ttcgtttctg ttcttctttg atgaattctt ttgtatcgac
    40861 aggattcaga ttatttagtc cgccaaaacc tgtatcgacc atttttcccc agccttttgt
    40921 cttctttttt cctgatttga gattctttgc tcgaagcttc tcactatgtt ttgctcgccg
    40981 atacttcaaa taaccttcta atcttcccat tagatccact gtttttcctc ctttttattc
    41041 aatcagacga ctcagctttt cctataacaa aataattgcc ttcagggtca gaaaaattga
    41101 aagtcaagat gccattgtta tctgtgattt ctcctggttc ttccatgttc tcgtagatag
    41161 tttcaaattc atccgtaaaa aatactaaag aaggcggtgg tcctaatacc tctggtgaaa
    41221 acttctgcac aaatactttt gggaatacgc ctaattctaa ttcttttgag atgctgagta
    41281 caatactctt aaattcttct ggcaattcga ttgtttcaga aatttctgca ccaatttttt
    41341 ctacaaagaa tcggcaaatc atctctacgt cattgacata aagcatcaca cgtgtttttt
    41401 gtatcatcat ttgacccttc tttctatttg attttctttc ctgtctataa actgattcca
    41461 ttatatcacg aaagcgcaaa caccttgtgt ttgatactat tcaagaaaaa taaagcaata
    41521 gtttctagga ttgctttcct ccacaaactt tttttacaaa aaaaaaacgg caatgaatgc
    41581 cgctcttctt atttcgattc ttttataatt ctgcttctga ttcatctttg gttagtgtgt
    41641 gtctaacact agttacgcca aatgtttgat cgattttttc cttcaacgct tcgattgcct
    41701 gtgcgccacg tgccgcttgt tcagcattga tggattcaat gaccagcacc gctgcttgtg
    41761 tttcttccgt cagcatcgtt ctttgggctt cacgccagtt gagacagcga cagatcgctc
    41821 cttgttcatc atagtagatg atttcttccg gaagtgccgg agcatcggaa tctgcaccta
    41881 aaggcaggaa tgattcgcca ccttgggctt ttcctaaatg cagatttcct gcgatctttt
    41941 cgatatcttc tccgccgcaa ggtacgccaa aagacaagga aatactatta tagatatcta
    42001 caagcggatt gattgggaaa aattcccgtt cttgatttgc acgtttcagt aaagcttcaa
    42061 tagaagaacg tgcacctttt ttagtcttga atgtggtaaa tgcctgacgc cactgagcaa
    42121 tgacttcgtt ttggctgaat gtttcttctg taaggtaatt tcttgcttct tttgctgcct
    42181 cattcaataa ttgatgatac gtttcttcac tttcttttgt tacgtggtta tcgataccat
    42241 ttacggataa gatttcgatg gttgcttcag gaaatacttc ccagaaattg gtatccacta
    42301 ttactttttt catctgttca cacctcttga ttagaataat tgcttgatga atagatagtc
    42361 tgtttgggga tcatctccca tataaaaaac atgttcgctg tatttgataa atcctttttt
    42421 acgataaaaa gcgagcgcaa catcgttgtg ttcccaaaca ccgagccaaa tggctgtttt
    42481 ttgcttttct tttgcttttt caatagctgt atctagtaaa aatgtaccga taccttgatg
    42541 tttaaatttt tttcgtacat agattcgctc gatttctaaa aaatgatcag ccatttcctc
    42601 agattgactc gttcctgtat ttagtttcag gtaacccgca ggctcttgat cgatactcac
    42661 taggaaaaaa tcggtttctt tatcttttag ctcttctgta agtttttcta gtgcataagc
    42721 ttgtgtcaag taatcagcta aatgctccgg tgaattatct tttccaaatg tatctgtaaa
    42781 tgtttcgata ctaatttgtt gtagtaagtc tacatctgaa ggcgtcattt ttcgaatttc
    42841 gtatttattc acggcttctt cctttcaata gatcctttta ttgccttttt tgacaaaatt
    42901 ccaatcttcg ctaacattct tgcatacttt atttaaaaga tattccaatt gttttgcttc
    42961 ttcgtcagaa agaccattta atgcgactgc attggagtag ttgttttctc gaatgatgaa
    43021 aggatagatt tctgctcctt ttttagtcgg atagagtttc ttgatttttt tattttcttt
    43081 atcttccaaa cgttcgatca tcccattgga ttctaatttc ttgattgctc gggcagtcgt
    43141 tgtacgatct actttgatca tttctgctag tttttcttgg atgattccag gattttcgca
    43201 aatacgtact aaataaagat actgtcctct tgttaaatcg acttctttga attcgatatt
    43261 gctaatagaa tctagcgctc gggcaatcat tccgatgtct cgaaggattt cagccatttc
    43321 atcccacctt tattttgttt gtaagactag ttcacctctt tttgttgcaa atgcaactat
    43381 tttcaataaa aaaatcaagt tcttttttaa taactagtaa agtatattct tttcttcttt
    43441 tacgaaaaag ctcaatcaca atagatctgg tttttgtttt ctaaaataag taactgtttc
    43501 ttcgttgttc gcttttctga tagctttggc aactcttcta tactaaaaaa tcccatgttg
    43561 gaagtttcat tattctcaat aaacttggcc tcttcaccgt ggatcgcaca agcaaaaaca
    43621 agtttataat actgaaaaag ctgtggaata tctttttgtt tattcgtatc aaaaactgct
    43681 cgcaactgag tagtttctac tgttaatcct gtttcttcat agacttcttt acgcacattt
    43741 tcttcaggag acaatcctat ttcagcaaat ccaccaggaa gtgaccattc tttcgtccgt
    43801 ttatcttcga ttagtaggac cttgccatct tttttgatat aggcacgaac atctactttt
    43861 ggtgttggat gtccttctcc aatcgttgtg agcgctttta tttcttcgaa agtttctttt
    43921 cctatttcac tgatcagttc caatgaaatc gtccggatct cctcaaaacg ctctttatca
    43981 aatacatctt ttccataata tagaccagct tgagaaagtg cgagtagtct tttgtattga
    44041 gccaacttct tgttcattct cttcccttct tttttagcaa atgtatgact atgtaatcaa
    44101 gtatagaaga ctggtttaat tacggcaaat aaatataatg aaatctgcaa taaataaaag
    44161 aatgttaaaa aactcgagaa caaaagacat tcgacttctc tggggctgtg aataaatggc
    44221 gttcaaaagc ttgcatctgc ggtaataagc cccaccaaac gaaaaatatg acgagctatt
    44281 cttgtctggc tgttcttatt aattgaggca ggacagcttt ttcacaacct ccccactaaa
    44341 cggtgttctc ctaccaactc ctcggtcaca agtcacaata ttcatcaaac atgagaagct
    44401 gtttttttga aattgctcct tgtgactcgg agctgaacga caggctcacg acctctcggt
    44461 aaacagcgtt caaaagccaa tttttcgata ttaagccatt tctttgttac ttattgtcat
    44521 tgatttcttt ttctaattta tccaatagtg gagtgtaatc cacttgagta tagtctgtta
    44581 catcaaattc atatagtgtt cctaactgga atttgtcata ttttcggtcg gcgatgatct
    44641 ttttgaatgc ttctttcgta atatgattgg tccctttcgt tcgatcttcc aatacgtcac
    44701 catagtgata atgatccatg atatagctca aatgacgatc tgattcacga tcacgtttgt
    44761 accgacgttg ccataacact tcaaagtctg ctgttaggcg aatcgtgatc acctgatatc
    44821 cgtatctatc tgctaattct tggagtcgtg ctttttgctt atcactaaaa ggatactcgg
    44881 acacaatcac tttctttcct gcttccatat acaaatcaag tgctttgtaa tagaaaggat
    44941 aaactttcgt cctttcttgt tccgcccgtt cttccaaatt gttaaacccg atggattctg
    45001 catagtattc cttgatttca tcgagcgtga tggcatacat atctggaaat cgttcccgta
    45061 gtttattcat aagatatgtt tttcctgtac caggactacc agccagaaga atgaaatact
    45121 ttttcatctc atttatttcc taagttaatt ggactttcca agttcataaa cagtccaatc
    45181 ttatgcttga caatttcttt tactgcttca tttgctggaa tcacattatg gcgaagagac
    45241 ttgttgattt ctgtttcact aaaggtttct ttagctactt tcgtccagtt gactaaaagc
    45301 tccgttccaa cattgaattt gcggatcccg ttattgatca attcaggata atcttcttct
    45361 ttcacacctg ttcctccatg gataactagg gggacatcaa ctactgcatc gatttctttc
    45421 agcaagggaa tgtttacttc tgtttttgat ttgaattgtc catgattcgt accgatagca
    45481 atagctaatg catccacgcc tgtagcttct acaaatttca ctgcgtcttc cggtcttgta
    45541 tataccttgt cattttcagc gacatggatt ccttcttctg taccgccgat tgttccaagt
    45601 tctccttcta cggaaacacc gtgcgcatgg gcatattcta ctactgcttt tgtcttcagg
    45661 atattttctt tgaaaggcag atgggaccca tcatacatga cagaagtata tccgctgtcg
    45721 attgcttctt tgatatcatc aaagtctcgg gcgtggtcta agtgcaagac tgcatcaacc
    45781 atttcttctt ctgcaatagc tgtcattaca ttgactaaca catgcatgcc gatatattta
    45841 gcggtatcga cacttgtttg aataatgatc ggcgaaccca tttcttttgc tgcgcctagc
    45901 atagcaggaa gcatttctag gttatgcgta ttaaaagctc caactgtaaa attcaactct
    45961 tctgctgttt ttgttacttc tttcaatgtt gtatacatct tttattgcca ccttatcttt
    46021 ttatttgttt cctttgatcg ttacttgttt tgcaatttgt cgcatctcat ccattttgcc
    46081 catgtagtaa tcgatccctt gatcatcacc agcacgagca gcatctgcac gcttctggtt
    46141 atagaggctc atcagttttt tatacccatc tccgatcgtc tgtttatttt ccaaactctt
    46201 ttctaaatat tggatggctt gatcgttcac atacaattca gaaaatttaa gtccaacttg
    46261 ttcataaagt ttcgctaatt tatgcttatc ttgggtagtg gaaatctctt gtttcaattg
    46321 tgtaatctct gattgaatct tttcggtcgc ttctggcgat agggcttttt cttcttttgc
    46381 cagaactttt ttcggttctt tttctttttt cttaaaaaat ccaaacatca ttttccctac
    46441 tttcaattaa aatgctttca aaactgggct taagatccag gcatataaga gtgctgcggc
    46501 tactgtatct acatcggttg ctgtagcatt gttgaatccc atcgaattaa agatcgttac
    46561 tagcaaagcg ggcaataatg taataaagaa accatgagca ataccgccaa tgatcgctcc
    46621 tcggcgtccg ccaactgcgt tgccaaatat ccctgctgtc cctccggcaa agaaattggt
    46681 tagcatacca ggtaaaatca tcgctaagcc gaacatgggc aaagtaaaca tggcaataat
    46741 cgtaccaatc gttgtcgtaa tgaaacctaa aatgacagca tttgggctat aaggaaagaa
    46801 aactggacaa tctaaggcag ggatcgcatc aggaactaat ttcatagcta tccctcgaaa
    46861 tgccggcacg atttcaccta acagtagacg tacaccagct agcaatacat acacacccac
    46921 tacgaattgg atggcttgta aaaaggcaaa catgatatag ttttgatctc ctgataattc
    46981 agaagcgaat ggttcgcctg caaataaaac agtgatgata tatagcggga ccatcacgac
    47041 catgacagac aaataagtat cttgcagaaa ttcgaaatgt gtcggcaact tgatatcttc
    47101 gatcgacttt ttattttcgc ctttctcacc aaaaagctta gcaacaccgg cttcaaataa
    47161 gtacccgatc gtacaaaaat gacctaaagc aatatcattt gatccagtga ttttacgaat
    47221 gatcggttgc gctactgccg gcatagcaat ggcgaaacaa gctccgataa aaccaccgac
    47281 caagatcaat acgatccctc gcagaccggc aaaatagcca aagactgtcg tcatcgttgc
    47341 catccataaa attgcttgac cagttaaaaa aatgtacttc cattttgtga aacgagccaa
    47401 aataatattg aatacaaaaa tggctaagaa cgtcagtgca atatctctac ctaaacccaa
    47461 atcattcatt gcttgaccat tgatagattc aatagaaggg atgatccctt gcatatgaaa
    47521 tccttcagta aagattttcc cgaaataagt taaacttcca acgatgatgc tcgaaccggc
    47581 actcaacact tgaaatccta ggagtgtctt taacgtgcca gagatgactt gtcctgctga
    47641 tttcttctgc agtagtagac ccaacatagc aatcaatgca atggtgatcg atgcctgagt
    47701 caaaatattt tcgatgataa aattgataac gcccatgtt
//
LOCUS       DAFELK010000016        47471 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFELK010000016
VERSION     DAFELK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.017"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(56..790)
                     /locus_tag="LP433_001127"
     CDS             complement(56..790)
                     /locus_tag="LP433_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL2005305.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1117..1527
                     /locus_tag="LP433_001128"
     CDS             1117..1527
                     /locus_tag="LP433_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBL2005306.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1520..2221
                     /locus_tag="LP433_001129"
     CDS             1520..2221
                     /locus_tag="LP433_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBL2005307.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2221..3807
                     /locus_tag="LP433_001130"
     CDS             2221..3807
                     /locus_tag="LP433_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005308.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3826..4047
                     /locus_tag="LP433_001131"
     CDS             3826..4047
                     /locus_tag="LP433_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBL2005309.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4044..4805
                     /locus_tag="LP433_001132"
     CDS             4044..4805
                     /locus_tag="LP433_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBL2005310.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5185..5694
                     /locus_tag="LP433_001133"
     CDS             5185..5694
                     /locus_tag="LP433_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL2005311.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5769..6308)
                     /locus_tag="LP433_001134"
     CDS             complement(5769..6308)
                     /locus_tag="LP433_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBL2005312.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6448..7059)
                     /gene="rpsD"
                     /locus_tag="LP433_001135"
     CDS             complement(6448..7059)
                     /gene="rpsD"
                     /locus_tag="LP433_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBL2005313.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7321..8172
                     /locus_tag="LP433_001136"
     CDS             7321..8172
                     /locus_tag="LP433_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBL2005314.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8200..8835
                     /locus_tag="LP433_001137"
     CDS             8200..8835
                     /locus_tag="LP433_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBL2005315.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8855..9628
                     /locus_tag="LP433_001138"
     CDS             8855..9628
                     /locus_tag="LP433_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2005316.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10036..10833
                     /locus_tag="LP433_001139"
     CDS             10036..10833
                     /locus_tag="LP433_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBL2005317.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10811..11224
                     /locus_tag="LP433_001140"
     CDS             10811..11224
                     /locus_tag="LP433_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL2005318.1"
                     /translation="MIDRSWSRKRGSFLQKEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11208..13853
                     /gene="mutS"
                     /locus_tag="LP433_001141"
     CDS             11208..13853
                     /gene="mutS"
                     /locus_tag="LP433_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL2005319.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13871..15979
                     /gene="mutL"
                     /locus_tag="LP433_001142"
     CDS             13871..15979
                     /gene="mutL"
                     /locus_tag="LP433_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBL2005320.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16001..16561
                     /gene="maf"
                     /locus_tag="LP433_001143"
     CDS             16001..16561
                     /gene="maf"
                     /locus_tag="LP433_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBL2005321.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16646..18634)
                     /gene="treP"
                     /locus_tag="LP433_001144"
     CDS             complement(16646..18634)
                     /gene="treP"
                     /locus_tag="LP433_001144"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBL2005322.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18857..19570
                     /gene="treR"
                     /locus_tag="LP433_001145"
     CDS             18857..19570
                     /gene="treR"
                     /locus_tag="LP433_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBL2005323.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19647..20093
                     /gene="msrB"
                     /locus_tag="LP433_001146"
     CDS             19647..20093
                     /gene="msrB"
                     /locus_tag="LP433_001146"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBL2005324.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20263..20865
                     /gene="ruvA"
                     /locus_tag="LP433_001147"
     CDS             20263..20865
                     /gene="ruvA"
                     /locus_tag="LP433_001147"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBL2005325.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20878..21879
                     /gene="ruvB"
                     /locus_tag="LP433_001148"
     CDS             20878..21879
                     /gene="ruvB"
                     /locus_tag="LP433_001148"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBL2005326.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21908..22486
                     /locus_tag="LP433_001149"
     CDS             21908..22486
                     /locus_tag="LP433_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2005327.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22538..23020
                     /locus_tag="LP433_001150"
     CDS             22538..23020
                     /locus_tag="LP433_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBL2005328.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23137..23511
                     /locus_tag="LP433_001151"
     CDS             23137..23511
                     /locus_tag="LP433_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005329.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24189..25541)
                     /gene="brnQ"
                     /locus_tag="LP433_001152"
     CDS             complement(24189..25541)
                     /gene="brnQ"
                     /locus_tag="LP433_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL2005330.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25688..26278
                     /locus_tag="LP433_001153"
     CDS             25688..26278
                     /locus_tag="LP433_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL2005331.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26406..27755)
                     /locus_tag="LP433_001154"
     CDS             complement(26406..27755)
                     /locus_tag="LP433_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2005332.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27923..28663)
                     /locus_tag="LP433_001155"
     CDS             complement(27923..28663)
                     /locus_tag="LP433_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2005333.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28676..30268)
                     /locus_tag="LP433_001156"
     CDS             complement(28676..30268)
                     /locus_tag="LP433_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2005334.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            complement(30836..31132)
                     /locus_tag="LP433_001157"
     CDS             complement(30836..31132)
                     /locus_tag="LP433_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005335.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31308..32033
                     /locus_tag="LP433_001158"
     CDS             31308..32033
                     /locus_tag="LP433_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBL2005336.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32026..32868
                     /locus_tag="LP433_001159"
     CDS             32026..32868
                     /locus_tag="LP433_001159"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBL2005337.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32871..33392
                     /locus_tag="LP433_001160"
     CDS             32871..33392
                     /locus_tag="LP433_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBL2005338.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33645..34208)
                     /locus_tag="LP433_001161"
     CDS             complement(33645..34208)
                     /locus_tag="LP433_001161"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL2005339.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34459..34728
                     /gene="rpsO"
                     /locus_tag="LP433_001162"
     CDS             34459..34728
                     /gene="rpsO"
                     /locus_tag="LP433_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBL2005340.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34916..37042
                     /gene="pnp"
                     /locus_tag="LP433_001163"
     CDS             34916..37042
                     /gene="pnp"
                     /locus_tag="LP433_001163"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBL2005341.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37552..37818
                     /locus_tag="LP433_001164"
     CDS             37552..37818
                     /locus_tag="LP433_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2005342.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37995..39953
                     /locus_tag="LP433_001165"
     CDS             37995..39953
                     /locus_tag="LP433_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBL2005343.1"
                     /translation="MTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40307..41608
                     /locus_tag="LP433_001166"
     CDS             40307..41608
                     /locus_tag="LP433_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL2005344.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41738..43108)
                     /locus_tag="LP433_001167"
     CDS             complement(41738..43108)
                     /locus_tag="LP433_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBL2005345.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVNPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43290..43613)
                     /locus_tag="LP433_001168"
     CDS             complement(43290..43613)
                     /locus_tag="LP433_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBL2005346.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43938..44546)
                     /locus_tag="LP433_001169"
     CDS             complement(43938..44546)
                     /locus_tag="LP433_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBL2005347.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44876..45592
                     /locus_tag="LP433_001170"
     CDS             44876..45592
                     /locus_tag="LP433_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBL2005348.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45605..46300
                     /locus_tag="LP433_001171"
     CDS             45605..46300
                     /locus_tag="LP433_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBL2005349.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46384..47013
                     /gene="udk"
                     /locus_tag="LP433_001172"
     CDS             46384..47013
                     /gene="udk"
                     /locus_tag="LP433_001172"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBL2005350.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15393 a         8787 c         9878 g        13413 t
ORIGIN      
        1 aataaaaaaa cttggtacgc aatcgctgta ccaagttttt ttatttagct tttgattaag
       61 ccataaataa taatttatat aagaatactg ctacgacacc agcacagata ggtgctacaa
      121 ctggtaccca tgcatatccc cattgagaag aacctttatg tttcaatgga agaagtgcgt
      181 gtacaagacg tggagcaaag tcgcgggctg ggtttagtcc aggacctgta ggaccaccaa
      241 gtgaagcaac taatgtccat acaaggaaac caagtgctaa gtgagctgta ccaagattat
      301 cttggaagaa tggtgctttt gtaataccta gggcaccaaa gaataaaacg aatgaaccaa
      361 agaattcatt gacgaaacca ttgaatttag aaccaacgct gttgattgtt gagaatgtac
      421 ctaacacatg gtttacgtct tctgtttggt cgtagtaagg tttgtaacaa gctactacga
      481 tcaattgtcc aatcgctgca ccaatcaatt gtgcaatgat ataaggaaca acttcagccc
      541 aagggaatag accattagat gctaaagcaa ttgtaaatgc tgggttgatg tggttaccgc
      601 tgattccacc aaaaatcatt gctggcatca taaccccgaa tccatacccg acagcaatca
      661 gcatccagtc actgccatat ccttttgtac cttttaaatc tacgtttgct acagcaccgt
      721 tacctagaac gattagtaat gctgtaccaa tcatttccgc cgcaagacgg gtcattagtg
      781 agtaatccat aaatacctcc aaaagttata aaaatgcaaa aaaaaaagaa acatcaacac
      841 gaaaagcatc ggtgcagtgt ttcgtgtcgg aaggatttct gcagtcttaa caaatgtgaa
      901 taaaaaaatg aattccatta cttataagaa accagaccaa cagtaaaact ccaactcttt
      961 ttaaaagttc tccacaaatc accaagctta actataaata taccaaaaaa aaaacgtttt
     1021 ttttctcaaa aattgtatct tagaaacagc atgttttgaa actttcagaa aaggtttgtt
     1081 agtaaaatga aagctatacg taaggagtgt tgtttgatga aattttttca agagtttttc
     1141 attattattt tcttttctgt attaggagaa ggcatacgga tttttgctca tttacctatt
     1201 cctggaagta tcttaggtat tcttttttta tttttagcat ttgaaatgca tcttgttgat
     1261 cctgaaaaaa tcggagcaac tggtgatttt ttattgaata atctagccat tttatttgtt
     1321 cctgctggtg taggtttatt ggaatatttt gatgatattg cttcgatatg gcctgtttta
     1381 ctgggagcag tcgtcgtgtg ttccatcgtc acgatggttg cagcgggaaa aacggcagaa
     1441 ggtgtagaag ctttgctggg ctatgtccgt aagaaaaaag cagaaagggt atctgtaaac
     1501 gaaatggagg agaatcaaat tgactgagtt ttttgtgaat ccattatttg gcttaagttt
     1561 gactttagga gtgtacgtat tatctgacaa atttttgcgg aaatataaac tgcctgtttt
     1621 gaatcctctc gtattatcga ttgttgttat tatcttattt ttgcattttt ctgggatcag
     1681 ctataaagac tataatatcg ggggcaattt tttgactatg ctgattactc ctgcgacagt
     1741 ggcacttgcc atccctcttt ataaaaactt ccgtttactg aaagagaatt tttatcctgt
     1801 aatggctgcg attttagcag gaatagtcgc aaattgcttg gttagtgtag ggttcggtta
     1861 cttcttctct cttcataaag agatggtgat ctcattacta cctaaatctg taacgacggc
     1921 tatttctgtc gatttatctc atacgatggg cggggtgaat gccgtgacac ttgctattgt
     1981 tgtctctaca ggtatttttg gttcgctgat cgccactcat attttccgcc tattcaagat
     2041 cgaaagtcca gttgctcgcg gtgtggcgtt aggaagtact tctcatgcta ttggtacagc
     2101 aaaagcaatc gagattggtg aaatagaagg aatcatttcc ggacttgcga tatgcgtcaa
     2161 cggaatattg accgttttat tgctaccgtt attctttcag ccttttgctg gcttgttttg
     2221 atgcgaaaac cactatttta tgctacaata accaaaacgt tcgagcataa aaaaggaggg
     2281 aaagacgtgt atttgtcttc cgagtatctt aaacaatttg ataaagatct atattataag
     2341 attctcctcc tagaaagttt tgaggatcaa gcttggcata ccgctgcaca attagcgcaa
     2401 gttgttcagc tggatgcccg cagcgtgtcg aaatacctga acgagctgtc taaaaactat
     2461 cagcagttta gcggtaagac acaccctttg tttacaaaaa atcaccgttc tggttataac
     2521 ttttatgata cgctcgattc aattgaacat gagcgttttt tgatctatct cgtgcaaagt
     2581 acgctgaaat tccagttgct gcacgacatt ttttttgaag aattccatac aatgtaccaa
     2641 tttgcgcaaa agcattacat tagtgaatct actgctcatc gaaaaatcaa tgaatggaaa
     2701 cagcaactgc aaacttacgg aattcggctg caacgaggta catatatcgc tcaaggcgaa
     2761 gaagaaatca ttcgacttta cttgcatatg acattctggc agttgtttcg agggaaaatc
     2821 tggccatttg aaacgatttc tcaaatggac gtaaagaata tggcagaaca tatcatggct
     2881 ttttttaatg ttcgtctgaa cgagatcaaa aaaagacgat tggaatatat gctaggtgcc
     2941 ttttttttaa gaaaatcaca gaagcattat gttgtattga atgagaaaaa aagacggctg
     3001 atttctgaca atctgttgtt ccagcgattt tgccaggtca tggagccggt atttcctaat
     3061 tattttcaag tagaagacga gttaggcgca ttatttcttg tactgatgac tcgtgaagaa
     3121 tattatagtg atcctaagat acggaagaaa atttttgatt ttcatcaaca agcaaaaaca
     3181 ccgcccttta cagccctttc agaagcaaaa gccgctcttt ctctttatca ggaagagcag
     3241 gggctgccag cagaaaatct aaccttcgag gcagaaaact atttattcag cagtcatttt
     3301 ttcgcctatc tttttcctaa tgcgaaagaa acgattgatg gcaatagtag tgattttatt
     3361 aatcatttag ttattgaaaa caaggaattg aaacaatggc tcgtacattt ttttgaaagt
     3421 agacacaaac atcccaatca tctggcattt aaaaatcatg cgtttttgat ggggcggtat
     3481 ctgactgtgt ttaaaacatt aggagccttt actccacagc ttccaaagat cacgatcctt
     3541 ttaatgacag atttcccatt atttgaagag caactgttag aggagggatt acggacattt
     3601 ttccgtaatg agtatcagct gatttttctg ccaacagatt atcgggggag agaagttgat
     3661 cttctgattt cgacaagtaa agtccaccgc aaaccatggg cggatcttga ctattttatt
     3721 gtgactgaag aactaaaatt aattgattac atccaactat ctcaaaaatt tgaaatgatt
     3781 caaaaacaaa aactattaaa acaataacaa agaaggagaa aaaagatgac atttgaagaa
     3841 attttaccag aattgaaaaa aggtgcaaag attattcgta aaggatggag tggatttgaa
     3901 ctttatgttg ttctcgtatc cgatgatgaa tttgatggct gtccggtgac gccgtactta
     3961 ttgatcaaaa caagtgacga aggtttttcc agcttcgctc ctacagtttg tgatatttta
     4021 gcagatgatt gggcgatcgt agaatgaaaa accagtatcc agatctagct aaacaggttg
     4081 tatttatcac aggagctgct tctggaattg gtgctgcgca agcccgagcg tttcttgaac
     4141 aagatgcttt tgtatttgga ttagatcaaa agttcggtaa aatggaagaa atttctttgc
     4201 gatttcctga aacttttgcc tacgcactag gtgatgttcg acaaatgaaa gaactccaac
     4261 aagcggtatc gaaatgccaa aatcattttg gtgaagttac gattttactg aatacagcgg
     4321 ggatattgga tgcctacaaa cccttgatgg aaactgacga atcgctgtgg gatctgattt
     4381 atgagacgaa tgtgaaaagc atgtatcagc tgacaaaaat catccttcct gatatgatcc
     4441 gccaaaaaag cggaacgatc atcaatatgg cttcgattgc tggcttgatt gctggtggag
     4501 gtgggatcgc ttatacaagc gcgaaacatg cgattgtcgg atttaccaaa caactcgctc
     4561 tggattacgc aggacagggt atccgagtaa aaggaattgc tccaggagcc atccaaacac
     4621 caatgaatgc ggctgatttt gaagggaaag gtgagatggc agagtgggtg gcaaatgaaa
     4681 caccagtcaa gcgatgggca cagccggaag aagtagctga gctgacgtta tttcttgcct
     4741 ctcctcaagc aagctacata caaggaacga tcatcccaat cgacggcgga tggttgttaa
     4801 aataaccttg tgtttttttc aagcttctgt atgataaaac taaagagaga aacaacggtt
     4861 gatgataaaa aaagtcgatg actgttcccg acattcgatg ccgaacagcc agttcaaaaa
     4921 attcttttta ataatcgtta atattcgaaa ctaagcggct tttcacgacc tcttgatata
     4981 aacgatattc aaaagcttgc aactgcggta acaagtccag ccaaatgaaa aatataagga
     5041 gctattttta tttgaccatt cttattactt gttgcagggc agctttttca ctaccttctg
     5101 cgacacttca gttggaattt tcttcccatc ctttggtcgc ggtcattacc aagataaaat
     5161 tatcttgcaa aggagaaata gaacatggaa aaaaataata cccgttcagc caaacgctgg
     5221 acaacgacag atgtgactcg gatggcgcta gtcactggtt tatatgtggc agtgacgctg
     5281 gttttgtctg tctttagctt tggagtgatt cagattcgtc tctcggagat gttcaactat
     5341 ctgtccttgt ataacaaaag atacatcgtc gcggtaacag cgggagtagc tttggctaat
     5401 attgcttctc ctcttggact gatagatgtt gcagtaggaa gcgtcagcac gctgcttgta
     5461 ttgcttatca actataaaat cactagtcgc atcaaaaaca tgaaaatcaa aatggccgtg
     5521 acagcatgcg tatttgcttt ttccatgttt acagtagctg gtcagctaac gattttatat
     5581 caactacctt ttttcttgaa ttggtgggtg attgctttag gagaattggc atcaatgatt
     5641 gtcggtggga taattattta ttggatcggt aaaaaagtgg atttgtcaaa ataaagatct
     5701 gtttaattta aaatagggca gcatggaaga gactgaatgt tgagtcttct tccatgctgc
     5761 ttttttgatt aatttgtatg aagaaatcga tttagccgtt ttttcatcaa gataccgata
     5821 taagctgctc cagttgcctt gattgcttcc ggcagtaaaa acggcagtag tccactggca
     5881 aatgcagttg taaaagtaag atcaccactt attttcagcc agatcgttcc gcagatcaat
     5941 gcagcaagag agcccattag attggcaaag attgcatata agtaatgagc atccgttctt
     6001 tcgatcatcc aaccagttat ccacgtttgt aagagaaatc caatcaaata tccgccagtt
     6061 ggcccaaata aaacagctat acctccagtc atccctgaaa atacaggaag accaatcaag
     6121 ccaagtaaaa gataaactcc aacagatatc aatcctagtt ttcttccgag aaaagttgct
     6181 gttaatccaa tagcaaatgt ttgccctgtc aaaggaacca aaccaaaagg aatggtcatc
     6241 tgagaaagga cagaaataat cgcggcaaat tccgcagcaa gtatcaattc tttcaatgtt
     6301 cggttcataa cgccctcttt tcgttaactt aatattttta tttggttaac gaaattgtaa
     6361 aacaaagtga ttactttgta aatagaaaat ataaaaaaag accagctatc caatagatag
     6421 cggtcttttt caagaaagct tttgaaatta taagctttgg ttgtagtatt caacgacaag
     6481 agcttcgtcg atttctggat atagttcgtc acgttctggt aaacgagtca atgaaccttc
     6541 caatttttca gcgtcaaagc ttacgaatgc tgggcgtcca acagttgctt ctacagcttc
     6601 ttttactgtt acgatgtttt gtgatttttc acgaactgag atcacttgac ccacttctac
     6661 gtggtatgaa gggatatcaa cgcgtttgcc atcaactaaa atgtgaccat ggttaactaa
     6721 ttgacgtgct tgacgacgag tcgttgcaag tcctaaacgg taaacaacat tgtctaaacg
     6781 ttgttctagt aagatcatga agttaacacc atgtttacct tctttgattt tgctagcttt
     6841 tacgaacaag ttacggaatt gacgttcgtt cattccgtac atgtgacgaa gtttttgttt
     6901 ttcagttaat tgcatgccgt attctgattg tttgccacgg ctattaggtc catgttgacc
     6961 tggtgcgtaa gggcgacgtg ctaattcttt tcctgtgcct gacaatgaga tgcctaagcg
     7021 acgagaaatt ttccatgatg gtcctgtata acgagacatt aaaatttcct ccaatgaata
     7081 taagtttttg gagtaaaata atccgttgaa aaattcataa tcatatagtt tgttcttcaa
     7141 tcttcacctt tgcagccgcg gttacacaat cgaacccgag acggggcaac aaactaggga
     7201 tgagttatta tttttctgct gcattatttt acacaaatta cagtatatga tagatcatcc
     7261 acgaatgtca agataattag tacataaaaa cgctttacaa acctaggctg tctttataaa
     7321 atgagagggt atgtgcaaat ggaaaaaagc gaaggaagtt taaggagaaa atcaatgaat
     7381 ccggtatcac cattatttga gaaaatcgat gcttcaattg aaaagaaggc gaatcttttt
     7441 gaaaacagct tttcacgtta cgctgttcga gcggttctcg cctgtttgtt tttgacttta
     7501 ggaacggctg tggcatttgc gatcgcgatg aagggggaag atatcgcgca tggtctagga
     7561 aagattttat acgcatttat gttcagctgg ggtctggtca tgattctata catgaacgcc
     7621 gaattaggaa catcgaatat gctttatatg accgtgggtg tttttcggca gagacttgct
     7681 ttaagtaagg cagccaagat tctatttgcc tgtatttttt tcaatatgat tggcggtata
     7741 ttatgtggat ttctaatttc tatgactacg ccatttcaag atttaacgtt ggacaacttt
     7801 atgttagaat caatagcagt aaaactagca aaaccttcag caacgatttt ggtggaaggg
     7861 atgtttgcga atatcgttgt caataccgct gtactgatca gcatgcggat gaaagaggat
     7921 gtcggaaaag tgatcacagt cgtattcatc attttcattt ttgctttttt aggatatgaa
     7981 cacgtgatag cgaattttcc tgcctttacg cttacttact ttgcttctca cggacagatg
     8041 gatggaatga cagtcagcaa tgtgttacat aatttgtttt ttgctttggc aggaaattat
     8101 attggtggcg gtttagtaat gggactggga tatgcttggc tgaatcagtc aaaatcatcc
     8161 tatgtggact aaaaagtcgt tcattaaagg ggaagtgcca tggaagtttt agtttttcca
     8221 aaaaatgagg aaaaagcgtt acaaatggaa aagtacatga aaaatctttt ttcctttgct
     8281 ggagtaccta agccggaacg cgctctttta caacaaccgt tactggatga gagcaaaaat
     8341 ttatctattt ctgaagtttt agcttttgtt cattattatt atgaacaaat cgaaagagag
     8401 tatcagtatg tagcgatcga tttagtccag aaaaacatca aacggcttac atttgaagac
     8461 ttagtcgtat tgttgccact agttcagaaa aaagaatggt gggacagcat cgactcttgg
     8521 agaaaagtat acagcacatg gtgtaaagcc tacccagagc agcgtgaaga agtctttcaa
     8581 ttgtttgaaa aaaaggaaga tttttggcta cgtcgaatag caatcacgtt gcaattaggt
     8641 tataaacagc aaacagacac aggactattg atccgagcaa tagacgaaga tcgtcaaaca
     8701 aaggaattct ttatccaaaa agcaattggt tgggcattac gcgattatag taagaccgat
     8761 gccgattggg taaaaagaca gctgacaaca gatttgagta agttagctgt tcgagaggca
     8821 agtaagtatt tataagaaag cgagacgaca agagatgaga cgcaaattat ttgcttttga
     8881 tattgatgga acgttgttag attcaaacaa acaagcttta gatagcacaa gagaagcatt
     8941 ggaaaaatta cgcaaagccg gtcatctggt cacgattgct acagggcgga gccgatttca
     9001 tgcgcaagag atcattcgcg atcttgattt tacgaactac attttatgta atggagcggc
     9061 cggtttttta gaccatgaac aagtatataa gaatttacta gatcgcgacc agttggatgc
     9121 gttcgttcaa gaagcgcatc atgagcagat cgatacagct tttgtcagct tagacaatat
     9181 caagcgttct tcttccaatg atgtaacggt gatggaagaa gcgatgcatt ctttcggtgc
     9241 tgtcttgcct gaattagatc agttttttgc agaggaacaa gaaatatacc aagcgttagc
     9301 atttttcgat caaacatatg atgggaagtt ctcttcatat gataaaattc gatttgtccg
     9361 ctggcatgag aacagtgtag atgtcgtacc taaaaatggt tctaaagcag cgacaattct
     9421 gcacttagca gaacaagtag gcatccctca tgaagacatc atcagctttg gcgatggaca
     9481 aaacgaccgt gaaatgttgc gcatgtcagg aattgggata gctatgggga atgctgtgcc
     9541 agaagtacaa gcagaagcta agatggtcac tgatacaaac gatcaggatg gaatttggaa
     9601 ggcattgaaa gagttaagcg tgatttaaaa gaggttgtga aaaagctgtt ctgcatcaag
     9661 taataagccc agccaaacaa aaatagctcc tcctattttt cgtttttctg ggcttattac
     9721 cgcagatgca agctttcgaa caccgtttaa ggaagaggtc gtgacagaag tggtcagttt
     9781 caagaaataa gaagggattt acgaaaattg cttctcaaat ttttgtaaaa ttacggctta
     9841 tttctgaaga agtagatgaa acaacgttta ttcgggaaat gggactgtga caagatgttt
     9901 gtcatagtcc cattttttta ttttattttt caaaactaag aaataccagg aaagagttcc
     9961 ttttgtttga ccttttcttt cttattgaaa acaactataa tatagagtga tgttaaaaga
    10021 gaagaggaat ttagtgtgcg ggtattgttt attggtgatg tagtaggttc aatgggacga
    10081 gagatgatta ctgaatatct tcctagattg aagaagaagt accgtccgca agtaacgatt
    10141 gtaaatggtg agaatgccgc ttctggacgt ggaatcacag aaaaaatcta taaaaaattt
    10201 ttgcaagacg gcgtagatgt cgtgacgatg gggaatcata cgtgggacaa ccgcggaatc
    10261 tttgagtttg taaatgaagc taaaaagatg gttcgtccgg caaattttcc ggaagggacg
    10321 cctggacaag ggatggtctt tgtcaaagtg aaccaagtcg aactggcagt gatcaacatg
    10381 caggctcgtt cttttatggt ggacttggat gatccttttc gtaaaatgaa tgagctggta
    10441 gaagaagcca gaaaacgtac gccgatcatt tttgtagatt ttcatggaga aacaacaagt
    10501 gaaaaacaag caatgggctg gtttttagat gggaaagttt cagcagtggt cggtacacat
    10561 acacacgttc agacaaatga tgcgcgaatt ttgccaagag gaacagcgta tctgacagac
    10621 gttgggatga caggtcccta tgatggtatt ttgggtatgc gcagagaacc tgtaatcgaa
    10681 aagtttctga ctgcattacc aaaacgtttt gaagttgtgg aacaaggccg atcgatttta
    10741 agcggctgta tcttggaatt ggatgatacg acaggtcatg caaaagaaat ccagctgatt
    10801 cagatcaacg atgatcgacc gttcatggag tagaaagaga ggcagttttt tgcagaagga
    10861 gccggaaatt caaaaagaag taaggaaact gacaaaactt ttaagagaga atgaaacgat
    10921 cattcgctac aaagaacttg aagaaaagat ccagcaaaac cagtatttag ctgagttgag
    10981 agaaaaaatc aaacaagcgc aaaaagatgc tgttcatttt gcccactatg acaaaccagc
    11041 agcagaaaaa gaagcaatca aacaagcgga tcaattcatg caagaatttg atcagcatcc
    11101 gcttgttgta gcttatagaa aacagctgtt ggaagcagat gatctgcttc atcatttaac
    11161 aactatgata caagaagaaa tcaatggaca aatagaggag gaaaaacatg cctcaaaaaa
    11221 ctaaaaatac tcctatgatg gaacaatatc taagcatcaa ggcccaatac caagatgctt
    11281 ttttgttcta tcgtttagga gacttttatg aactatttta cgaagatgcg atcaaagcgt
    11341 cacagctttt ggaattaacg ttgacgagca gaaatcgaaa tgcagaagaa cctattccta
    11401 tgtgcggtgt acctcaccat gcagcacaag gatatatcga tgccttgatt gaaaaaggct
    11461 ataaagtagc gatttgcgag caggtagaag atccaaagac gactaaaggg atggtcaagc
    11521 gcgaagtgat ccagctagtc actcctggta cagtcatgga cagcaaagga ttgtcggcaa
    11581 aagacaacaa ttttttaaca gctgtagtta gtcaaggaaa tgaatttggc tttgcttatg
    11641 ccgatttaag tacgggagaa ttgaagacgg ctcggttgca tgatgaagaa gctgttttaa
    11701 atgaagcctc tgcattgcag acaaaagaac tcgtattagg cagtgagatc actgataccc
    11761 ttcgtgaaca gctaagcggg cgtttagggc tagtcttttc tcaacaaaat gagatggaag
    11821 aaaacgcgga atttagcttt ttgacaagcg aactagtcga tccgctggaa aaagaagcaa
    11881 ccggcaaact attgacttat ttatcggtga cacaaaagcg gagtttagct catatccaaa
    11941 aagcagtaga ataccaacca gatcattttt tgaaaatgga ttattattca aaattcaacc
    12001 tagaattaag ccaatctatt cggactggga aaaagcacgg cactcttcta tggttgttag
    12061 atgaaacaaa aacagcaatg ggtggccgtt tactaaaaca atggctagac cgtccgctta
    12121 tccaggcaaa acaaattaaa gcaagacaag aaatggtcgc ttctttgcta gacagctatt
    12181 ttgaacgtat cgatttgcag tcagcattaa cgaaagtcta tgatctggaa cgcctagcag
    12241 gtcgagtagc tttcggtaat gtcaatgggc gagacttgat ccagctgaaa acttctttag
    12301 aacaagtgcc aatgatcaga gggttgattg aaggaatcga tcaaggtcaa tggcaaagtc
    12361 tgctttcaga aatgcagccg atggaccatc tcgtccaatt gatcgaccaa gctatccaag
    12421 atgatccgcc gttacaaata acggaaggaa acatcatcaa agatggattc aatgagcagc
    12481 tcgatatgta ccgttctgct atgagaaacg gaaagaaatg gttggcagaa cttgaagcaa
    12541 aagagcgtca agaaacagga atcaagaact taaaaatcgg atttaaccgc gttttcggtt
    12601 attatataga aattacaaaa gcaaatcttg gaaatgcaga actggagaag tatgaacgaa
    12661 aacaaacttt agcaaatgca gagcgtttca tcacaccaga actaaaagaa ttggagacac
    12721 aaatcctcga agcagaagaa aaatctgttg atttagaata tcagttgttt ttagctgtga
    12781 gagaagaagt caaaaaggct atccagccgc tacaagtact tgcaaaagca atcagtgcag
    12841 tagatgtgct acaaagtttt gcaacgatca gcgaacgcta tcagtatgtt cggccagaac
    12901 ttgtcagtga caagcatcag cttctgatca aagacggacg acatcctgta gtagaaaaag
    12961 tattaggaca tcaggaatat atccctaaca gcgtagaaat ggcagaagac gaaatgatct
    13021 tgctgattac aggaccgaat atgtctggta aaagtacgta tatgcgacag ttggcattaa
    13081 ctgttctgat ggcgcaaatg ggctgtttcg ttccggcaaa acaagcagtt ttacctattt
    13141 ttgatcggat ttttacccga attggtgcaa gtgacgactt aattgctgga caaagtactt
    13201 ttatggtaga gatgatggaa gccaatcaag ccctgcgtta tgctacgcca aacagtttga
    13261 ttttgtttga cgaactaggg cgaggaacag caacctatga cggaatggcg ttggcccaag
    13321 caatcatcga atatatccat cgtcatgtac aagcaaaaac actcttttct actcattatc
    13381 atgaactgac ggtacttgag aaagaacttc cgcagcttaa aaatgtccat gttggagccg
    13441 ttgaaaaaga cggagaagtt gtcttcttgc ataaaatgat ggatggacct gcggataaaa
    13501 gctacggcat acatgtggca aagatcgcag gattgccttc caatctacta gaacgagcag
    13561 cagatatcct gcatacgcta gaaaatggcg ataacggaca ccatactgtt ccagctgaag
    13621 tagaagagaa aactaaaaca gccaaacagg agcaaataaa accacctgca gaaaaagtaa
    13681 atcaagacca tatacaagac cgtgtaaaag aagaaaacca acagctttct ttattcagtg
    13741 aattatccga aaatgaaaca gaagtcattg aatcactgaa gcaaataaat ttactagaaa
    13801 tgacgccaat ggatgcacta aacacattat atgaattaca aaaacaactg taggaagaag
    13861 gcggatatcg atggccaaaa tccaagaatt atctgaacgt ttagctaatc agatcgctgc
    13921 gggagaagta gtggagcgac cagcttccgt tgtgaaagaa ttagtggaaa atgcaattga
    13981 cgccggcagt actcagattg atatcttagt tgaagaagcg ggactgcgga cgatccaagt
    14041 gattgataac ggagaaggca ttttggcaga cgacgtagag aatgccttca agcggcatgc
    14101 gacaagtaag atccataatc gcgacgatct ttttcgcata cgaacgctgg gctttcgagg
    14161 ggaagctttg ccaagtattg cctctgtttc tgaaatgact ctggaaacgg cgaatcagga
    14221 agaaaaacaa ggcacctatc tgtcgctgaa aggcggagaa gttattgagc atcgaccagc
    14281 accactgcgt caaggaacga agattaccgt cagcaatctg tttttcaata cgccagcccg
    14341 cttgaaatac gtgaaaacac tgcacacaga attagcgaac atcggggaca tcgtcaatcg
    14401 actggcattg agtcatccat cgattgcttt tcgtttagta catgatggaa acaaaatgct
    14461 ggcaactgct ggaaatggcg atctgaaaca aacaattgcg ggaatctacg gattatctac
    14521 cgcaaaaaaa atgctgaaaa tcgaaggaaa agatctagat tttgagttat ttggctatgt
    14581 ttcattgcct gaggtgactc gtgccagtag gaattactta tcgacgatca tcaatggacg
    14641 ttttatcaag aacttttcct tgaataaagc aatcgttgca ggttatgggt caaaattaat
    14701 ggtcggtcgt ttccctattg ctgtattgga aatcaaaatg gacccgcttt tagtagatgt
    14761 aaatgttcat ccgacgaagc aggaagtccg gctgtcgaag gaaaaagaac taacagagct
    14821 aattagtaac gccattcaaa aagcattgtc tcaagaaaat ctgattccaa gtgcagcgga
    14881 taatctacgg tttaagaaaa aagtacctga tcagcctaaa acagaacaaa tcgaaatcga
    14941 tttgtcctac gcttttgaag aagaaaaacc taaaaagcca agtagtttga attttgatcg
    15001 agagacaggt acctttttcg tagaagaact aaagaacaca tttgttgaca gaattgttga
    15061 taagtctgtg gaaaatgttg aaaactattc tggtttttct gaagaaaaca ccacttatcc
    15121 agaaaaaaca gcgaaaacgg tggataagtt tggtgaaaat gttgataact ttgtagaaaa
    15181 aacagtggaa aaatctgaaa agaaagaatt tcccattgtg gataacatgg agaaaacaaa
    15241 tgaagaacaa gcagataaat ccgtagaaga ggatgaaaag atttacgagg aagaattgac
    15301 actccatcct gaatttgatt tcactcaagg aaacgacaaa acattagaac aagccatcaa
    15361 gaaattagaa acggaaaaac cagtacaacg ttttcctcag ttggaatatt ttggacagat
    15421 gcacggaacg tatctttttg cccaaagtag cgatgggttg tacatcattg atcagcatgc
    15481 tgcccaagag cgcattaagt atgaatattt ccgggaaaaa attggggaag tatctgatga
    15541 tctgcaagaa ttgcttgttc catttgtgtt agactatcca aacagtgatg ctttgaaatt
    15601 aaaagagcaa aaacacttgc tagaagatgc agggatttat ttagaagaat ttggtcaaaa
    15661 cagctttatt gtacgggccc atcctacttg gtatcccaat ggagaagaag aatcgattat
    15721 tcgggagatg atcgatatgc tgctgacaac tggaagtgtg agtgtaaaaa aattccgtga
    15781 agcaacagca atcatgatga gttgcaaacg atcgattaaa gccaaccatt atttgaatga
    15841 agcacaagca cgtgtgctgc tgaaggatct ggcacgatgc gaaaatcctt tcaattgtcc
    15901 ccatggccgt ccagtattga ttcactttac caattcggat atggaaagga tgttcaaacg
    15961 aatccaagac ccgcattaag tcaaagagaa gagggaaaac atgaagattg tattagcatc
    16021 ccaatcacca agaagaaaag agttattggc tcatatcgtt tcagaattcg agattgaacc
    16081 tgctgatatc gatgaaacgc catttccaga cgaacagccc gtcgattatg ttcgtagaat
    16141 ggctgaagaa aaagcacgaa ctgtctggga acaagatgaa aaagaagacc atttagtgat
    16201 tgccagtgac acgactgttg ttctcaatca agagatcatg ggtaaaccag aagatctggc
    16261 tgaggctgaa ttcatgctga aaaaactaag cggggaaaca catactgtat atacagctgt
    16321 tgttttaaaa acaaaggaac gagaagaacg gatactagca gaagcacatg tcacttttta
    16381 tcctttgaca gacgaagaga tcaaacgcta cttggagacg ggggattatg cggataaggc
    16441 aggggcatac ggcatccaaa atgctgcgag tgtattcgtc aaagaaattt ctggagatta
    16501 ttacagtatc gtaggatttc cgattggtgc tgtcaatcag gcactgaaaa cattcattta
    16561 aacaaaaaag cggactatct gattttcgat tgaaaatcca tgatagcccg ttttttttat
    16621 tgaaaagatt acttatctac tctgactaag attttacttc agctttaccg actgcttcgc
    16681 ccgggcgaac aagtcctgat tggtcaagag aaagtcctgc aactttttca ttattggtca
    16741 aagcaacaat aatgtcagtt ttcttgccag cttgttctat ttctggcaaa tccatttcag
    16801 caatcagggt ctctggtgtg acaaggtatc cttctttcac gaatacattg aaaggaacac
    16861 cctttagttc aacagtatct aatcccatgt gaacaagtac ttccagcccc tcattagaaa
    16921 gaataccaat ggcatgtttt gtttcaaaga cactcgtcac tttaccgttt actggtgcat
    16981 agactttgcc gtttgacggt tcgacagcat aaccgtcacc catcattttt tgtgagaaaa
    17041 ctgggtcatt tacttcagtt atttccttga tggtccctgc agcgactgcg aataatgttt
    17101 cttttgttgc aactgccgta ccagttgctg aaacaggttc gaaagactgt ggcgttgctg
    17161 ttgcgccatt tgctgtttga agttgtacat cagcagcatt ttcaggaaca gcaggatcaa
    17221 tcttattcaa aattccctga cgtctaaaga tgatcgtcaa gccaaatgga atgatgacag
    17281 caatgatcat tgcgatgatg aaaggtaccc atgtttctgc ttggatagct agtattcctg
    17341 gcaaaccgcc tactccgatc gcgttagctc gaacacccat caagttagca aacatgccag
    17401 ctaatccaga gccgaccatt gcagcgacga aaggatagac gtatttcaaa ttgattccga
    17461 acatagcagg ttcagttacg cctaagtaac aagaaatcat tgctggaatc gagatttgtt
    17521 cttctttttt attcccacga tgtaagaaga tgatggctaa gactgcagag ccttgggcga
    17581 tatttgataa agcaatcatc ggccataaat tcgttgatcc gaaatctgca atcagctgca
    17641 tatcgatggc attggtcata tggtggagac cagtaatcac taaaggagca tacaggaatc
    17701 cgaatacggc actaaacaac cagctgatag aagacgtcaa tccagtattt acgatatttg
    17761 agatccagct tccgactgtc cagccgatag gacctaaaat aacgtgtgca gctaaaacag
    17821 ttggtaacaa tgaaaacaat ggaacaaaaa tcatcgagat cgactgaggg atatatttgc
    17881 ggaagaagat ttctagatac gctaacataa accctgccag catggctgga ataacttgcg
    17941 cttgataacc aatcatctgg acttgagcaa aaccaaaatc ccaaaatgga atatctgctg
    18001 cggctgtgga agctacacta taagcattta ataattgcgg agaaactaac gtaattccta
    18061 aaacgattcc taatatttgt gtagtaccca tcttttttgc aatactccaa gtgataccta
    18121 ctggaagaaa atggaaaatt gcttcaccgg gtaaccacaa aaaggcattg acaccattcc
    18181 aaaacttcga gtgttcaacg attgttccac caagactttc aaactggata ccttcaagta
    18241 catttctgaa tccaaggatc aatccaccga caatgattgc aggaatcagt ggtgtaaaga
    18301 tttctgctaa aacggcaata gcacgttgaa cgggatgaag gttttgtttt gcagctgctt
    18361 ttccttgttc tttggaaacc ccttcaactc cagatactgc aacgaagtcg ttataaaaag
    18421 tagaaacatc gtttcctatg atgacttgga actgtcctgc attcgtgaac atccctttta
    18481 cgctaggtat atcttcgatc gctttttcgt ccgcttttcc tggatcattc aggacaaaac
    18541 gcatacgagt cgcacaatga ctaactgcag caatattttc ttttccgccg atatcatgta
    18601 acagcttctc ggcatctgct tgatattttg ccatatcaat aaaccccttt ctcttaactt
    18661 gtctatgcaa gttgtttctt catttactat actttttttc ggagagaatt gcaagcgttt
    18721 tattaaaaag tacgagagaa aatgatatcg ttttaaaaag cttaaaataa gcttttctta
    18781 aaaataggaa cattgaaata caaaaagagc tgtagtatag tgaagaaatg atggaagaac
    18841 gagtgaggga aaaaacatga ataagttcaa tgaaattttt ttagatttgg aacagaaaat
    18901 tttagcgaaa gaatatcctc cgcattcgct tttacccagt gagaaccaat tgatcaaaat
    18961 ttatggtgtt tcacgagaaa caattagaaa agcgctgaat cttttgacta cggaaggtta
    19021 tattcaaaaa aaacaaggaa aaggttcgat cgtactggat cggaatcgct tcgactttcc
    19081 tatttctgga ttgactagct ataaagagct acaggagacc caacgtattc caagtgaaac
    19141 gatcatccat acgttagaag aaacagaagt gacaaaagca ttgaacgaga tcactggctg
    19201 ggagatcggt gcgcctgttt ggcatttgat acgcgaaaga aaaatcaatg gcgaagtagt
    19261 tatattagac accgattatc tattaaagga aatcgttcct attttaactc cagcacaagc
    19321 acaaggatcg atctatgaat attttgaaaa tgagctttct ttgacgattg cttacgcgca
    19381 aaaggagatc acagtagaag aagtaacgga aatcatgaaa acagcgatgg atcttcacga
    19441 tgacacttat gcagtagtag tcagaagcct cgttcatctg gaagataccc gctgtttcga
    19501 gtattctgag tcggttcacc gattagataa attccgtttc gttgagtttg cccgacgccg
    19561 aaaagtgtaa atagttcaaa agaaagcaaa ttgttggcat ctgtccactt tggcgctatg
    19621 ataggatcac aaagggggca tttttaatgg ataaaccaat aagaccagaa aaagaagaac
    19681 tgaaagaaaa gttatcaccc atggcttatg cagtcacaca agaaaatgca acagaacgac
    19741 catttagcgg gaaatatgat gatttttacg aaaaggggat ctatgtagat atcgtcagcg
    19801 gtgaaccgtt attcagctct gcagaaaaat atgatgcagg ttgtggctgg ccatcattca
    19861 gcaaaccaat aacgaaaaga caagtgcgcg aaaaagccga tttttctcat ggcatgcatc
    19921 gaatagaagt tcgaagcaaa gaagcagatt ctcatctcgg acatgtgttt accgatggac
    19981 cagtagatca aggtggtcta cgttactgca tcaattctgc ctcactgaaa ttcattccat
    20041 atgaaaagat ggatgaatta ggttatgggg aattcaaatc acttgtagaa taatggaaat
    20101 acacaaagag cggtacaata cggggattta ctcgatcgtc cgctcttttt ttattcaagc
    20161 gattgctatt tgaaagaaac gctccctaga ctcctttttt cacaaggtga aatgtgctac
    20221 aataaaggga acgtatgtgt gcaaaagaaa gaggactaga atatgtatga atatctgaca
    20281 ggtgtggtta cctttatcaa cccctattac atagtagtag aaaccaatgg tatcggctac
    20341 cagatcgcac taggaaatcc ttaccgctac agtagcaaac taaatcaaaa aataaaaatt
    20401 tatgtccatc aggtaatacg tgaagatgcg catcttctgt atggatttga ttcgctagaa
    20461 gaaaagcaac tgtttttgcg attagtaagt gtttcaggaa tcggtccgaa aagtgccctt
    20521 gcaatcatgg caagcgaaga ccactccggt ttgattcaag cagtagaatc cagtgatgtc
    20581 acttatttga cgaaatttcc aggagtaggg aaaaagacag cacaacaaat gatcttggat
    20641 ctaaaaggaa aattcggtga gctgagtatc gatacacctt ttagtctatt tgatgaagca
    20701 aacacaaaag acgctacagc tctatctgaa gcaatggaag ctctctcggc tcttggttac
    20761 agtgatcgag aaatcaaacg tgtagaaaaa caattaaaag aagtagataa tcagacaacg
    20821 gatgagtatc tacgccaagc actcaagcta atgatgaaaa aataaggagg agaccaaatg
    20881 acagatgaat acttgttatc accagaatct ggcgaaaatg aactgagttt ggaaaaatct
    20941 cttcgaccac agctgctttc tcaatatatc ggacagagaa aagtcaaaca agaacttcag
    21001 atttacatcg aagctgccag aaatcgggaa gaacctttag atcatgttct gttgtacggg
    21061 cctcctggat taggaaaaac gacgatggcc atggtcattg ctaatgagat gaccgtaaat
    21121 attcgtacga cgagtggccc tgctatcgaa cgtccgggtg acttagtagc aatcttgaat
    21181 gaactggaag caggggatgt cctgtttatc gatgagatcc atcgattacc tagagtggta
    21241 gaagagatgc tttattcagc tatggaagat ttctatgtag atatcatggt aggacaaggg
    21301 ccaaccgcac atccggttca tttccctctt cctcccttta ctttgattgg cgcgacgaca
    21361 cgggcaggta tgctttctgc acctttacga gatcgatttg gcatcatttc tcatatggaa
    21421 tattatgacg aacaggatct gcaggagatc gttttacgtt cttcggatat ttttcaaaca
    21481 gagatcattg aagaaggggc attggaaatt gctcgccgat cacgaggaac gcctagaatc
    21541 gctaatcgct tgctcaaacg ggttcgtgat tttgcgcaag tccaaggaga cgggaaaatc
    21601 gatcgtccta tagcggatca ggcacttact ttgctacagg tcgatcaggc tggattggat
    21661 tatgttgacc agaaattgtt gcgaacaatg atcgagttat atggcggcgg accagtaggg
    21721 ttaagtacgc tttcagtaaa cataggagaa gagcgtgaga cggtagaaga tatgtatgaa
    21781 ccgtatctga tccaaaaagg atttttaaag cgtacaccta gagggcgaat tgctactgct
    21841 tatgcctatg aacattttgg ttacgactat catatatgat ttttgctttt agattggagg
    21901 aaaatgaatg agtgatacaa cacgtacgaa acaattgatc aaaaacgtat tgattgattt
    21961 gtgccaaacg caatcttttc gaaaaatcag cgtccaaaaa atcgcaaacg aagcaaaaat
    22021 caatcgacaa acattttatt atcattttac agataaatac gatttgcttc gttgggtcta
    22081 ttgtgaggat gcattgcatt atttagatcc acaatgtctt tcacttgata attgggaaga
    22141 gcaagcattg aaaatgctga aagcaattgc tgagaagaaa gaattttatg caaatactgt
    22201 gctttctgac ccagaaattt tacaaaaaga gttttctcaa ctgatccaaa aatcatttat
    22261 caagattttt gaacaaatgg atgaagaaag acaactttct gcaagagaca aactatttta
    22321 tgctcgtttt ttttcttacg gttgcagtgg tgtattagtc aattggatca cgaatgaata
    22381 tgaagaaaca ccgatggaaa tcgctatgca gcttttccgt ttagccaagg atacggaatt
    22441 atattcttat cgtctttatg caaaagaaga gttggaagaa cagtaataga aaaatttttt
    22501 gttggaaaag caataatcgc taaaaggaga tggggaaatg acaaaaattt tatttgtttg
    22561 tttgggaaat atttgccgtt caccgatggc agaaggcttg ctgagaaaac gaatagcatt
    22621 agaaggaagg gaagcagaat tttttgtgga ttctgctgct acaagcacgt atgaagttgg
    22681 aaagacaccg caccctggaa cgaaaaaaat attaaaccaa gaaaaagtag atatgacgaa
    22741 tatggttgct cggcaaatca caccccacga ttttgaaact tttgattgga tcattggcat
    22801 ggatcaagaa aatgtagaag aactgaaacg aagagcacca cgctcagcgc aggggaaaat
    22861 ccatttgttt ttaagtagca ttcctggaaa agaaaaagaa aatgttcccg acccatacta
    22921 taccaataac tttgatgaga catatcactt gatcacagaa ggcctgaatc attggtggaa
    22981 tatttggatt gatgaaaata aaataacaaa caatttgtaa agttaacgct ttctttttaa
    23041 ggcgatgtta gagcatttcc ttgttttttt gtaaaatgtt aggtaaaata aaattaatta
    23101 agtaacactt tcttagctaa aggaggagtg cattcgatga acgaagagac agtatcgcca
    23161 atgaagaagc ttacgaagtt agttactcat acttcgtatc aactttttga ttcttttgta
    23221 aatgacactg aagaacatgc taagaatgta cgattgcaag gaaagtttat tcttgagctg
    23281 caaaaagctg ctactgaaca tagtctagtt atcttacaag taagagcaaa tcgtttgagt
    23341 agcaagtatg aaacgatctc aggctgggtg gcgacaaaaa cggtcgaaaa agaccgagtg
    23401 atgatccgcc tacaaaacga agagcagcag atccggatgg ttcctgtaga acaaattgaa
    23461 aaaataacaa tcctttcacc agcaggggaa caggaacggt tatcaaaata atttatacca
    23521 gatagaaaag cacgtatgag cttgtaccat caatcattac taatcaaaaa taaccgaatg
    23581 ctttaagctg atatcagtaa aacggaacgt tttaggatga gtatcacagc atgacagcat
    23641 tgggttgatt agttgaatcg attggatggt acaagttttt ttgataaaaa aaggtcctgc
    23701 tagccgggga gctagcagga taaggagtta aaaatgaaaa agtgttgtta gggttgtttg
    23761 ttggtatgct tatataatag tcactagttg tgaatatttt gtgacgaaag ttttcgaaag
    23821 ttgttaagtt tttttgcgaa aactattttt atatcatata tatgtctaaa atctatatta
    23881 taaaagaaat gttgtttgat cagcttctct tcggtattag ttcaaaacaa aacggcaaag
    23941 tatatggagc tactttgccg ttttgtttct ctaatactca ggtcagttta tagacgctca
    24001 ataaacggtg ttcaaaagcc agtttctcgg tattaagtca aatttatgca aaaatgtgag
    24061 aagccatttt caaaaaatat ttcttaatac tcgaaactga gcggcttttt cacgacctct
    24121 caataaacag tgttcaagag acagcctatc ggcaataagg ctgaacgtct ctttcacaac
    24181 ctcttttatc aatctgctac ttcttctttc ttagcgaaac tccaaatcag tccgataaca
    24241 aaaccgataa ctgctggtac gatccacccc atccccaatt tgaaaaacgg caagtagctt
    24301 tccgcaacat ataaaagatt ttgaacaata ggtgtttgtt tgatagtttc tgggcaagcg
    24361 ttcaacccat caaaaatcga agcaatcaat gtaaaataag tagtcattcg ataaacagcc
    24421 gtacgctgct taaacaaagg accaactaac actagtaaaa tcagtgtcat tgctaatgga
    24481 tagatgaaca tcaaaacagg caacgaaaat tgaatgatat tcgtcaagcc tacgtttgcc
    24541 gctaaacaag gaaggatact agcaagtgca acaaagaatg cgtaatttct ttgcggaaac
    24601 aaatctgtga atgtttctgc aaaagctgta atcaaaccaa taccggtctt caagcaagct
    24661 aatataacga taaatgctaa taagatactg ccataagtac ctaaataatg atcagcaatc
    24721 tgagccagcg tgatcccgcc attttcactt agagcaaagc tacctaagct catagcacct
    24781 aaataagcga gcaaagtata aatgattccc atcaatataa tgctgatcgc accagatttg
    24841 atcgtgtctt tagcgatttc agcaggtttt gttacaccca tgttttggat tgttgtgaca
    24901 atgatgatcc caaatgctaa agcagcaagc gcatctaatg tgttatatcc ttgagtaaac
    24961 cctgtgaaaa aagcatgctc ttgataattt ggctgaatag gcgcttgatt tacagaacct
    25021 agtggattca aaaaagcaag gagaagcaaa gcacctaata aaaccaaaaa tgcaggattc
    25081 aggaactttc caacataatc taatatcttt gtcggttttc ttgaaaacca ccaagccagc
    25141 acaaaaaata caatactgaa aattgctaga tatagcgtct gtctgctagg atcgataaat
    25201 ggtgctaaac caatctcgaa agatgtggtt gcaaggcgag gtaaagcaaa aaacggtccg
    25261 ataactaagt aaagcaagat ggtaaaaacc atcgcatatg tttgatttat ccgttttgct
    25321 aattcatata cacctgagct tttcgataca ccaatggcaa tcacccctaa gaagggaaga
    25381 ccgataccgg taaccaagaa acctagattc gcccaaaagg tagcagcgcc tgcttcttga
    25441 cccaaatgaa cgggaaagat aagatttcca gcaccaaaaa atagaccgaa aagcatggag
    25501 cctataaaaa gatagtcttt aaatgataat ttttttgtca tacataactc ctttacggtt
    25561 tttttaaaag taacaaaatt tcgaaaaata tgcaacaatt ttcagaaaat ttcctatata
    25621 aaacgacggt tatttaataa cgtaagtgat aaaataaaag cgctgaatca tctgaggagg
    25681 aatcatcgtg acaaagtcga gattagaagc atttactgat ggagtggtag ccattgtttt
    25741 gagagttctt gtattagaga tcaagatccc taatacatct agctttcatt ctttatgggt
    25801 catccgaaat acattattag cttataccat cagctttata tttgttgcgg tgatctgggt
    25861 gaaccatcat cgtatatttc agatggcaga acgaattaat taccgagtgg tctggtcgaa
    25921 tatctttttg ctcttttggc tgactttatg tccttctgtt actagttggg tcgggcgtaa
    25981 ccctgaagct ttttggcctg agatggctta tgtcttagta tacacgatgt ggagtttttc
    26041 ttttggtatc ttgatgaggc aaatcatgaa agcaaataaa ccagattccc atgtcgtgag
    26101 agttttgtca aaggaccgtc gaagtcttat ctccatgatg attaacttat gcttgattgc
    26161 cggtgtcttt tttgtaccgt tgatcgggtt attcggacgt ttttttgtat ctggtatttg
    26221 gattttttcc tataaaaaag cagatgccta ttatcagcgg ttgtttccgg ggaaatagaa
    26281 aagaggctgg gacagaagct tttaactcca agaaataagc cgaaatttca caaaaattta
    26341 agaagcaatt ttcgtaaatt ccttcttatt tctcgaagct gaccacttct gtcacaacta
    26401 ctttcttact tcttacgttc atatttcata tgatagatta gtaatagaag caagaaccac
    26461 acaggtgtta gtaataaagc gattctcgta tcttttccta ggaacaagac gacacacaca
    26521 aaggccatgt aaagaaatac cagataatta ctaaatgggt acaacggcat tttaaatgaa
    26581 tgagcttttt tgccgaggat acttttacga tatttcatgt gcgtgtagac aagcatactc
    26641 cagataaaca agaaacaagt agtggcaata ctgcttacta gtgtgaatac ttcactaggc
    26701 atcacgtaat tcaagataac agaaatgaaa atgacgatag tagaaaatgt caaagcattc
    26761 cctggcacat gatgtgttgt taactttttg aattttttag gggcactgcc ttcttgcgct
    26821 aaagaacgaa gcatacgtcc tgtactatat attgcactgt tgcaggcaga agctgctgca
    26881 cttaatacga ctaaattgat caaggaagca gcaatcgtga tcccaatttc cgaaaatact
    26941 tctacaaatg gactgttatc tggattcaag ctgttccatg gatagattgc cataatgaca
    27001 aaaagagatc ctaagtaaaa taagatgatc ctgataggaa tattattgat agcttccggc
    27061 aacacttttt caggattttc tgtttctcca gcgactaatc caactaattc tatcccagca
    27121 aaagcaaagg ttaccatttg gaaagctaag ataaatcctt ttgcaccagt tggaaagaat
    27181 ccgccatgag accatagatt cgtgatactg gctgtgccaa tatctgtcgt atagtgggtg
    27241 aggatcatat aagctcctac gaggataaag gcaatgatcg ctacaacttt gatcaatgca
    27301 aaccaaaact ctaactcacc aaacaatgag acagccacca tattcaagca aagaagaaga
    27361 cctaatgcaa tcagttcagg aagccactga ggaacaccag gcgcccagta gcgtacatac
    27421 attccgatgg ctgttaaatc ggccattgca atcgataccc agcagaacca atacgtccag
    27481 ccagtgatga aagccgcttt tttgccaaga tattctgcaa caaaatccag aaaagaatgg
    27541 ttattggtgt ttgataacag aagttcgcct aacgcacgca taatgaaaaa acagatgcat
    27601 ccagtaataa gataggcgag caatatcgaa gggccagcta gctggataga ctttccggaa
    27661 cctaaaaaca accccgttcc aatcgctccg ccaatagaaa tcagttggac atgtctattt
    27721 ttcagtccac gctgcagttc ttgctcttca ttcattttta aatcatccta actaaaaaag
    27781 tttaattact tccatattaa aagagttttc tgaaaaacac aactaagatt ccaaaatttt
    27841 cagaaattta ccttttatga gtaattcata aaaaagaact gcggtaaaca ccgcagctct
    27901 ttgtcccaat cagctattga tcctaagcat ttaaaatacg tgaaaggaat tcttttgtac
    27961 gttcttcttt cggatggaca aagatatctt ctggtgtacc ttcttctgca atcacacctt
    28021 tatccataaa aatgacacgg tcagatacat cttttgcaaa ttccatctca tgcgtcacga
    28081 taagcattgt caagccagta tgtgctaagt ctttgatcgt attaagcact tcgccaacca
    28141 tttcagggtc taacgccgaa gtaggttcgt cgaatagcaa tacatctgga ttcattgata
    28201 atgcccgagc aattgcgaca cgctgtttct gtccaccaga taattgtgct ggtttggctt
    28261 cgatataacg atccatacca actttttcca gattttcgat tgctactttt ttggcagttt
    28321 ctttatctcg tttcaggaca gttgtttgac cagacataca gttttccaag acattcatat
    28381 tgttgaacag gttgaaggat tggaaaacca tacctagatt cgttcgatat ttaggtaaat
    28441 tatatttagg agctaataca ttttctccat tataaatgat ctcgccgcct gttggttttt
    28501 ccagtaaatt gatacagcgc aagaaagtag atttaccaga accggaagaa ccgatgatcg
    28561 tcacaacttc acctttattg actgttacgc tgatatcttt caatacttca ttttcaccga
    28621 agctttttct tagatgtttg atttcaataa ttttttcatt catgattctt cctccttatt
    28681 cctgcaaatt tgaattgtcg atttcttcaa gcttggtata agctgaagga ccatcgattt
    28741 tcttttctac cgcccgcagg attctggtga tcgtaaaggt catgactaag tagatgatcc
    28801 cgacgatcgt aaatgtttgg aagaattgga aattcgcacc ggaagcagag tttccttgga
    28861 agaacaaatc agctacgccg attacactta aaactgctgt atctttgata ttgataacaa
    28921 actcatttcc tgttgctggc aagatattcc gtaaaacttg tggaataaca acttttctca
    28981 tcgtttggcc atgggtcata ccaatggctt gcgcagcttc gaactgccct tcatctactg
    29041 caaaaatccc cccacgaacg atctctgtca tgtaagctcc agtattgaga gagacaataa
    29101 acaaagcggc aatcgttcgg ttcaatgaaa tgccaaaagc gagtgccaga ccgtagaaga
    29161 tgaccattgc ttgtaccatc atcggtgttc cgcggaatac ttcgacatag atagaaagaa
    29221 gtgcatttcc gattttttgg aagaagcgag tcagtgcatt tcctgattca ggtaccgaac
    29281 ggaagacacc aatcagtaat ccaagtgtag taccgacaac tgtcccgatc aatgcgatga
    29341 acaaggtaag tccagcacct cgtaagaaca tattgccgta ttgtttccaa atcgtagtga
    29401 aatcagaaat gatgccaggt ttttcttcac tatcagttgc agcaggctga tctttgactg
    29461 cttggtccat aattttggtt cgttcatcgt tagagatgcc agaaagaatc tggtttactt
    29521 tttggatatc cgggtcgcct ttacgcatac caacagaaat ctgaacatct tccgggtttg
    29581 tctggaagcc atctgcaccg ctgaattcaa gcatttccaa gtctttgttc acactagttg
    29641 ccgttacacc ttccggacgt tcgctgacat aaccatcgat cattccagaa gctaaagctg
    29701 ttctcattgc tgagaaatta tccattgctt gttgtttctg cacatctggt atctgatcga
    29761 tcacagtata gtggaatgta tttaactgag cagtaatctt tgctccagaa agatctgcta
    29821 aactttttgc ttttgcatat ttgctatctt tttgaactac tactactaat tgtgattcgt
    29881 aataaggatc ggtaaaatca atttcttttc gtcgttcagc agtagggctc attccggcga
    29941 tgatcgcgtc gatcttgcct gattgaaggg caggagccag accatcccat ttcgtttgga
    30001 cgatgactaa ttttttccct aaaccatctg ctactttttt agcgatttga acatcataac
    30061 cgccggcgta actattttgg ccttgaattg gcaaggcatt attctcatct gtttgttgag
    30121 accagttgaa gggtgcatac ccagcctcca tacctacgcg aaactcatcg ctcggtgttt
    30181 tttcatctgc atttgccaga gatcccacac tgaatagtga gaagacaaaa gcaaatagta
    30241 cggcaactga aaccatattt tttttcattt ttttctccct ttctgattat atgatacacg
    30301 agcggtctag atgaaatgcg gtaaagcttt atctgaaaaa ataaaaagcg accgatttat
    30361 agatataaaa aggccgctaa aattccataa ggtgataaac ctctcacaaa acatagcgca
    30421 acttagcatc actgctaaga cagtccgcaa gctcttaact tgcgtcccaa catacactcc
    30481 aagcaaaaaa gtgcacattt cggcgatcct ccctattcct gcttctccat gtttgcttca
    30541 ctccacaggg ttaatgattc tcgcgacctc tacctcattg attgaggcat ctcgtattca
    30601 gttatttata caaaaaaagt ttacgatact cgagaggctt tgtcaatcta taactgctgt
    30661 tttttgaaaa aatactgata aatatagaaa tctttacttt taccgaaaaa acaatcaaaa
    30721 tgtgaatcat ctatccattg caaacgatag tataattata cacaaaaatg tatgtaatac
    30781 aataaaaaaa gaactagaac agaaaatttc ctgtgtccag ttccatctcg atcatttaag
    30841 ctgccgcttt ctttggctca cgtcctagga tcgcttgcaa aagaacaacg acgccataaa
    30901 tggctaatat tagataaatc aaacttgagt attgggtgat tccccagccc catgttcgat
    30961 atacggctaa tgtaatggct aaaacaattg cggcaatcac gttgaataaa gcaaaagccc
    31021 aaagatttcc attttctttg cgtacaagat aaaaaacaga gaaataaacg cttaacgcta
    31081 accaggcgat acaagccaga ataacgcccc aataaataaa gaatggtaac atatcgattc
    31141 acctcacttt tatacagcag tattgtaaca cgttttcatt cttttgtcag tgaacattgt
    31201 gataaattgt tcaaatgccc ataacacttt tttattccca tttttctgac ttttcaacaa
    31261 taaatttgtt cgagtatggg ctataatgga aagtgaggtg acaaaacatg aaacaattaa
    31321 cagtagacga agcagcaaaa gagatattag cttatcagca aattacattt ttgaccggtg
    31381 caggggtatc cacaccttct ggagtgccag actatcgatc tttgtcagga atctaccacg
    31441 ggatggagca gccggaatac ttgctgagtc atcaagcaat ggtgaatgaa ccggataaat
    31501 tctatcaatt tgtcaaaaag atttatcatc ctgaagcaaa acccaatatc attcatttgg
    31561 aaatggcaca tctagcgaaa gaaaaaaatg tttgggttgt ttcccaaaac atcgacggtt
    31621 tgcacgcaaa ggctaaaagc ccgcaactcg tcaattttca tggaagtttg tatcaatgtc
    31681 attgtcgaaa atgtcaacaa acggtagact ggaaagaata tcttcacagc gacaaacatc
    31741 aagcatgcgg aggacaaata cgcccagaca tcgtgttata tggtgaaggg tttcaagatg
    31801 gagtcatgga gcaggcggct tatgccgtca gccaagcaga gctgatcgtc attgttggaa
    31861 cgagttttca agttcatccg ttttgtgatc tggtacagtt tcgccagccg tcagccaaaa
    31921 tcttagtaat caatcaaacg cctgtttatt tagcggagcc ttatacgttt attcaagaag
    31981 acggagcggt tgttttcaaa aaaatacaag aattaggagc agattatgac tgaattcaaa
    32041 accgaaaaag aaaaaatgat tgcaggcgag ctttattttg ccaatgatcc tgagctggtt
    32101 gccgaccgta tgtttgcaag aagtcaaagc caaatcatca accaagcaga atcagcggaa
    32161 ctgcgatccc aattgttgaa agagactttt ggccgtacag ggaaaaaaat ctatatggag
    32221 ccagttatca attttgatta cggatataat atatttgttg gggagaattt ttatgcaaat
    32281 ttcaattgta catttttaga tgtcagcacg attgaaatcg gtgataactg catgttcgct
    32341 ccgaatgtcc agctttacac ggcgacgcat ccactacatc cagtgaaacg taacagcggt
    32401 ctggagtacg caaaacccat taaaatcggt aataatgttt ggttaggcgg aggagttatc
    32461 gtcacgccgg gtgtcactct aggggacaac gtagtagtcg gcgcaggttc ggttgtgacc
    32521 aaatcttttc ccgacaatgt agtgattgca ggaaatcctg ctcgtatcat caagacagta
    32581 gaggaagaac taacagaaga gtctcttgaa acattacgtc ataagatcga tatgatcgat
    32641 cgagagttga ttgctttatt agaaaaaaga atggatacgg taactaaaat aggacaagtg
    32701 aaaaaagaag aaaaccaagc agtttatgat gcaaaaagag agcagcaagt attggataaa
    32761 gttgttagtc tgctgaaaaa taagggatat aaggaaacaa taacagatac gtatgttgat
    32821 ttgatgaaac actcgcgcga ataccaaaac aaaatgaagg aggaataagt gtgatcgaag
    32881 gagagacacg gcgaaaacaa atcatgcaaa ccttggcaaa tacagaaaaa ccagtgagtg
    32941 ctagcaagtt tgcgaaaact tttggagtca gccgtcagat cattgtaggc gatattgctt
    33001 tactacgagc tgcaggtaaa agtatcgtgg caacagcaag aggttatatc ctcgaaacag
    33061 aagaaaccaa tactgggcac atcagtaaaa tcgctgtcca gcatggaaaa gatcaaacag
    33121 aagaagaact gagactaatc gttgaaaatg gtggtgaaat cattgatgta attgtggaac
    33181 atccccttta cggtgagtta gcaggaactt tgcacatcaa aacgccacaa gatatcgatt
    33241 cctttatgag acgttatcaa aaaagtaatg ctactttgtt atccgaatta acaggcggca
    33301 tccatctgca tacgatccgc tacccagaaa agcatatgct gaaaaacatc aaacaaaaac
    33361 tagctgaagc aggaatcctc tacgaaggat aacatcgtag ctgctacttt ttatcctaga
    33421 aactattcta tcatctctga gataaacacc catatggaag aaataagaaa aaataagaaa
    33481 agatgcgtat ccaatacaca gaattttttg gaattgcgat ttctagatgt ctatctaaat
    33541 ttcgattagt ggagaaacat aaaaaaggga agtgcagctt ttgagcactc ccctttttta
    33601 taaagctttc ttgtagcata gtatcgaagg aacctgccaa ttctctactc gatcaccaat
    33661 acgccttctt ttagtgcaaa tggattttga tcgttgatgt ggtcatagaa catcacaccg
    33721 ttgatatggt cgatttcatg ttgaacgacg atcgattcat aattcttcaa acgaatcttg
    33781 tgtttttcac cattcatatc ataataagac acagtgattt tggcatggcg aacaacatat
    33841 cctggtactt ctcgatcaac agataaacag ccttcacctt cccctaaaca agcatcttga
    33901 acagaatggc tcaaaatttt aggattatac ataacagtac ttagagaagg tccatctgcc
    33961 tctgggtcag gacttggtac gtgaacagca atgattcttt tagaaatatc taattgagga
    34021 gcagctaagc caacaccgcc tcgtaagtgt agttcttcag ctttgattgg atcttggctg
    34081 ttttttaaga actcaagcat ctcttttcct aaagagatat cttcttcgct taatggaaga
    34141 gaaacttctt ttgcaacttc gcgtaaggtc ggatttcctt cacgaatgat atcatccatt
    34201 gtaatcatgg aatatgtacc cctttcttaa aagactgtgt ttcaagtcta ttttcgcatt
    34261 atagtttacc acaaaaatgg aaaagtagta gtaagattgt ttgaaaacta ccttttctta
    34321 atgattaact acttgatttt caacccggtt tcaggtaaag tatagctgtg tgctctaggc
    34381 acatgacctg ccacttggtt aagcgaatca ccaacgtttt actcagtcgc aggggaataa
    34441 tcgaaagagg tgaaagaaat ggcaatttca aaagaacgca agaatgaaat catcaacgaa
    34501 tacgctcgcc atgaagggga tactggttct ccagaagtac aaatcgctgt attaactgaa
    34561 gaaatcaacc acttgaatga acatgcacgc gtgcacaaaa aagaccatca ttcataccgc
    34621 ggcctaatga aaaaagttgg tcaccgccgt aacttgttag cttacttacg taaaactgac
    34681 gttcaacgtt accgcgaatt gatcaaacgt ttaggcttgc gtcgttaatt ttagtcaaaa
    34741 agagtgggat tcacatgaat ctcacttttt ttactcgtat atcaattaag taaaattccg
    34801 tgatcaagct agatggactc ctactaacca aatgaaagct gctcaaaaga cggctttcgg
    34861 cagttttcat ttgtttagta gcgtcttgct ttcacgagaa ggaaaaggag aagttatgtc
    34921 agaaaaacaa gtattcaaaa cgacatgggg cggccgtccc ttacaaatcg aagtcggtca
    34981 gctagcaaaa caagcaaacg gagccgtttt agtccgttat ggagatacag tagtcttaag
    35041 tgcagctgtg gcctctaaag aagcaaaaga tacagacttt ttcccattaa cgatcaatta
    35101 tgaagaaaaa atgtatgcag cagggaaaat ccctggaggt ttcatcaaac gagaaggccg
    35161 tccaagtacg gaagcaacat tgactgcccg tttgatcgac cgtccaattc gcccgatgtt
    35221 tgcagaaggc ttccgtaatg aagtccaagt aacgaacatc gtgatgagtg tagaaacaga
    35281 ctgctcgcca gctatggcag caatgctagg ttcttcttta gcactatcaa tctcagatat
    35341 cccatttgac ggcccaatcg caggcgtaga agttggtcgt gtaaatggcg agtacgtctt
    35401 gaatccaaca gtagaacaag cagaacaaac agatatcgaa ttgactgttg ccggaacgaa
    35461 acaagccatc aatatggttg aaagcggcgc gaaagaagtt tcagaagaag acatgcttgg
    35521 tgcattgctg tttggttttg acgctatcaa agagttagtt gctttccaag aagaaatcgt
    35581 tcaagcagta gggaaagaaa aaatggaagt gactttactg caagttgatg aagtattgaa
    35641 aaaagaaatc tttgatgctt cttacgctac aatgaaagca gcagtaatga ctgaagaaaa
    35701 acttgctcgc gaagataata tcgagcaggt gaagatcgat atccgcgaag cttatgctga
    35761 gaaatttgca ggtcatgaag atgaagatca cttgttgaaa gaagttaaac aaatcacaga
    35821 agatcttgaa aaagatgtcg tacgtgaatt gatcaccatc gataagatcc gtcctgacgg
    35881 gcgtaaattg gatgaaatcc gtccattgtc atcagaggtc agcttattgc cacgtgtaca
    35941 tggatcaggt ttgttcacac gaggacaaac acaagcttta tcagcttgta cactcgcacc
    36001 tctaggagag caccaaatca ttgatggttt aggggtggaa gtcagcaaac gattcatcca
    36061 ccactacaat ttccctcaat tttctgttgg ttctacagga cgtgcaggct ctccagggcg
    36121 tcgggaaatc ggacatggcg cattaggtga acgtgcgtta gcacaagtaa tcccttcaga
    36181 agaagaattt ccttatacga tccgtttagt agcagaagta ttggaatcaa atggttcttc
    36241 ttcccaagca agtatctgtg ctggcacatt agcattgatg gatgcaggtg taccaatcaa
    36301 agcgccagtc gccggtattg cgatgggact tgtttctgat ggtgaaaact atacgatcct
    36361 aactgatatc caagggctgg aagatcatct tggcgatatg gactttaaag ttgccggtac
    36421 aaaagatggt atcactgctt tacagatgga tatcaagatt caaggaatca cagaacaaat
    36481 cctaactgaa gcattaactc aagcaaaaca agcacgtatg gaaatcttag aagaattgac
    36541 ttcaacgatt gctgctccac gtgaagaatt aagccaatat gcaccaaaaa tcgaaatgat
    36601 ccagatcgaa cctgctaaaa tcaaagatgt tatcggtaaa ggcggcgata cgatcaacgg
    36661 aatcatcgat gaaactggtg tgaaaatcga tatcgatcaa gatggaaaag taagtattgc
    36721 ttcagctgat gcagaaatga tcaaaaaagc tatcaagatc atcgaagatt tgaccaaaga
    36781 agtcaaagtt ggtgaagttt atctagggaa agttgtccgt atcgaaaaat tcggtgcatt
    36841 cgtcaacttg atcaaaggaa aagatggact tgtccatatt tcccaattag caaacgatcg
    36901 tgtcaataaa gtcgaagatg ttgttaaact aggtgatgag atccttgtga aagtaactga
    36961 aatcgataaa caaggacgcg taaatctgtc aagaaaagca atgttgaacg aagatggttc
    37021 aacgaaaaat gaagaaaaat aatttaattc ataggaataa tgtacttgtg atcgtgaagg
    37081 tgacaggggg acaataatta ttcgaaaaaa ggggactgtg acaaaagccg tgtcacagtc
    37141 cttttttttc gaataaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaag
    37201 ttaaaaacat taggagctgt ttttatttgg ctgttcttat tacttgatgc agaacagctt
    37261 ttttacaacc tctccaataa acgatgttca atcagctgtc cctcgatatt agctcaaaaa
    37321 acggcaaaat atgaggaact atttttccgt ttgtttctct aatactcagg tcaaaccgct
    37381 gatttcacaa cctctgattc acggtgttcc agaagcagct tctacggaaa taagctgaac
    37441 acttttgtta caacttcttt ttttctggag tttcttggcg catatttttg gagtccttct
    37501 gaataaagcg taaaataaaa gtgagaaata tggataaagg agggaaagga gatgctgaat
    37561 tttttatggt cgttatttat cggcggtata ttaggtttga tagctggcgc aattttagga
    37621 aaggaagtcc cgggaggcgt atctggaaat atcattatcg gttttttagg tagttggctc
    37681 ggcgaatttt tactaggacc actgggaccg gaactcggcg gtttttattt gataccagca
    37741 ttattgggtg caattttttg ccttgctctt tattcatttg tggcaagacg tatcagagaa
    37801 cgtccaaaga aagaataatt ttattcaaat aagttgacac ttcagtgtgt tacttggata
    37861 attagaagca atttaggaaa gcgggtgtca tggataagaa tatcatctat cattcaagct
    37921 tacctaaagg atatccatat aacaagaaat gagggaaaaa cgtggcaaca acgcacaata
    37981 ccaaaaagat atcaatgact ggcctgcttg tagcgatggg agtcgtctac ggagacatcg
    38041 ggacaagtcc gctttacgtt atgaaatcga ttgttgaaga taatggcgga ttgtcaggaa
    38101 tcaatcctga ttttgttatc ggatcagtct cattgatttt ttggacattg actctactga
    38161 caacaatcaa atatgtcgtg attgcattga atgcagataa ccatggtgaa ggtggaattt
    38221 tctcactcta cacacttgtc cgaaaaggtg ggaaatattt gatcattcct gcaatgatcg
    38281 gaggagctgc cttactagca gatggggtat tgacccctgc tgtgacggta acgactgcga
    38341 ttgaaggctt gcgaggaatt ccgcagtttt ttgaccggtt cggtaataac cagaacgtga
    38401 tcgtcattat cactttagtt attatttttg ttttattcat ggtccaacgc tttggtacag
    38461 atattgtcgg aaaagcattc ggaccaatca tgttcgcttg gtttactttt ttaggcgtaa
    38521 tgggattaat gaacttcagt caagactgga cagttatccg tgcactgaat ccttattatg
    38581 ctatccagct gctttttagt gcagataaca aattaggctt gttcattctt ggaaatattt
    38641 tcctggctac gacaggtgca gaggcgcttt attccgatct tggacatgtc ggcaaacgaa
    38701 atattcgtct gagctggcct tacgtcaaaa tttgtttggt tatcaattat tttgggcagg
    38761 ctgcgtggtt gttgaatgtt tatcaaaacc ctgaagcaca gcaaatcaag aacctgaatc
    38821 cattcttcca aatgatgcct caaagttgga tcgtgatcgg cgttgctttt gcaacagtcg
    38881 ctgcagtcat tgcttcgcaa gcattgatta caggttcgtt tacgctagtt tcagaagcaa
    38941 tcaagttgaa actgctgcct cggttaaaga tcatgtatcc tgggaacagt atcgggcaaa
    39001 tgtatatccc agcagtcaat ctgattttat ggatcgcctg ttctctagtg gttgtcacat
    39061 tccgaacgtc tcatcatatg gaagctgctt acggtctatc gatcactgtg acgatgttga
    39121 tgacaacagc actgctttac ttttatctta tccaaaatgg gcattctcgt tggcttgcat
    39181 atttagttac ctttttcttc ggtgcgatag aagtcgtttt ctttatctca agtgttgtca
    39241 aattcttccg aggcggtttt gtagccgttc tgattggttt gatcatctta gtcgtgatgt
    39301 ttatttggga acaagggaac attattcgcg aatcgtcaac cgaggatgtg tctttgagag
    39361 attatatccc gcagcttaga gaattacgtg atgatacttc tttaccaatc tatcagacaa
    39421 atgtggtctt cttggttcct gatatggctg aagataaagt tggccgacag ttcatctatt
    39481 cgattttaga taaacggcct aaaagagcac gagtctattg gtttgttcat gtggaagtga
    39541 cggatgagcc atatacgaaa gaatatcaag tagatatgat ggacactgat tttattgtcc
    39601 aagtgaatct gttcttaggt ttcagggtcc aacaggaaat caacgtatat gttcgccaag
    39661 tcatccatga tttgatgaaa caaggccgtt tgccaaaaca gccacaaaga tactctctga
    39721 caccagggcg agaagttggc gatttccaat ttgtcctgat tgatgaagta gtttccaatg
    39781 tgacaactct aggaaaatgg caacgtcaaa tcatgcaggc aaaactggca atcaaaaaaa
    39841 tcgctacctc gccagaaaca tggtttgggc tagagtacag cgaagtaaaa catgaaactg
    39901 ttccgcttat cattggaaat actcggaaaa catggttgaa agagcggttg tgaaagtagc
    39961 gctttgacct gaactaatgt cgaatgtcag ctacttgaac accgtttatc agaggtcatg
    40021 aaaaagctgt actgcaacaa gcagtaagaa cgagcagata aaaacagctt ctcatgtttt
    40081 tcatctgttt gggcttaatg ccgtagatgc aagcttttga ataccgtttt tatcagaggt
    40141 catgaaaaag ctgtttagca acaagtaacg caatgatttt gaagtgataa ggagatgtgg
    40201 ctgaaaaatg ccgcatctcc ttttttattc ctaaatatga atacgcatta ttttcaatct
    40261 ttttgtagaa aaagggtaca atagaaaaag agaaaggcgg gagaatatgg ttatcaattt
    40321 cattatttta tttttgatga ttgcaattac ttcatttttt gtagcaagtg aatttgcttt
    40381 agtgaaaatc agacgatcaa gattggaaca actagaaaag gaaaatgtaa agaacgccaa
    40441 gctagctctt catgttacac accatttaga taactattta tcagctagtc aattaggaat
    40501 tacgctaacc ggtttgatca tcgggtgggt cggtgaagga tctgtcgcgg ctttactaga
    40561 accagtgatc ggtaaactac cttttagttc ggctattagc agtacaatct ctgtggcgct
    40621 gggatttatt ttagttacgt atatcgatgt ggttattggc gaactgcttc ctaagagcta
    40681 tagtatcgtc aatacggaga aggtcgtctt gttcgtagtt aaaccacttc attattttta
    40741 taaagtaatg tttcctttta tttgggtatt gaatcattca gctgcagggc tagggaagct
    40801 attaggtgtg cgtctcgtat ctgaaggaga agagacattg tctcaagaag agctgacatt
    40861 agtcgcattg aattcttatg aaaaaggaga gttgaccaaa gaagaatatt attatttgga
    40921 aaacgtgttt gaatttgatg ataccttggc aaaagatata caagtagacc gtacgtccat
    40981 gcaagtattc gaagcttcag aaaccgtcaa agaagcgata aaagcttcga ttgaacaagg
    41041 acatactcgc tatccggtta tcttagaatc aaaagacaat gttttaggtt atgtcacctt
    41101 gccagatttg atcaagcaat cttataaaga tgaccagctg acagtagaac agttgattga
    41161 agagccgatc gtaacaactg aaacgatccc tataaaaaaa ttattgacga tcatgcgaaa
    41221 aaagggtaag catattgcta tcttaaaaga tgaatacgga gggacaagcg gcttagtgac
    41281 gattgaagat attttagaag aaatcgtcgg ggaaatccga gatgagacag atttggacga
    41341 agcattgata gcggaacagt cagatggctc ttatatcatc tccggcaaac taacattaga
    41401 tgatttccag cgttattttc atgtagagat tccagagttt gaagaaacga attttactac
    41461 acttgcgggc tttgcttcta gccgatataa agaaataaaa gcaggaacaa tcattgagat
    41521 tgcatcattc cgtttcacgg tattagaata ccagcatgca catatcgatt atttcaaagt
    41581 agagtccacg gaaagaaaaa cagaataaaa gaaaaaaggc tgtgacattt tttgtcacag
    41641 cctttttgtt atctaaaaaa cctgttttcg gtaaacgaag aagatatttt caataaaagt
    41701 tttcattttt agccgcaacg atttctttta atcaaggcta tcttgcttct gcatgttcta
    41761 atgtgaaatg ttcctcttca cccatgtgtt tcaattgttt catcgaacgc atataagagt
    41821 aaagcaacac ggcaacagaa ccgatccaag ctaaaggaga agctgctgct gctcctgggt
    41881 atccccacat tcctgtaaga acgatagctg caaaagaacg cataagcaat tccatcatac
    41941 cggcgatcgt agggatcttg ctttgtccaa gcccttgaag tgtgtagcgt aaaatgaaca
    42001 ggactgctaa gatccagtaa agagacccat tgatattgaa gtaggtttgt gctaattcaa
    42061 atacacgtgt ttctgatggg ttaacaaaca attgaacaaa gaaatgaccg aagaaaatga
    42121 cgatagcacc tgctaagaga ctaaatccga cactcatcag taaagtttga cgtacccctt
    42181 gcaagattcg gccatattct ttcgcaccat agttttgtgc agtgaaagtt gccattgcaa
    42241 taccaaatga catcatcggc tgatttgcaa attggtcgat acgaccagca gcggcttgag
    42301 cagctacgac atctgtccct agactattta gtgctgcttg taacacgata gcaccaacag
    42361 cgatgatcga agattgaaac gccattggca aagcagcatt taggtgtaca gcaaactctt
    42421 ctttttcaaa tttgaaatct tttttgcgta actgtaacaa aggcattttt ttcttgatat
    42481 acactagaca cagtacgctg gaagaaactt gtgcgattac tgtagcaata gctgcacctt
    42541 ccacacccat gccaaaatag ataataaaga tcaaatcaag tacgacgttg atgatgaccg
    42601 caatgatcag aaagaatagt ggtgtgcggc tgtcaccaag tgcgcgaatg acattagaaa
    42661 gcaaattgaa actgactgat gcaaagatcc ctaataaaat aattgaaata aatgtttgtg
    42721 cttgatcaag tatttcagga ggagtttgca tcaattgaag catcggacga ataaacagga
    42781 gacttaggac agttaaaatc acagtgacga caagactaat gacaacacta gcagcaaaac
    42841 ttttcttcag accccgataa tcttttgcac cgtaacgttg tgcggtaata atggctaaac
    42901 cagctgttaa accttgggca aagccaatga tcaaaaatgt caggcttcca gttgcaccaa
    42961 ccgctgccag cgcattttta cctagcgtct gacccacgat gatcatatcg atcatattgt
    43021 agaactgctg aaaaacattt ccgatcagta aaggaacagt gaacatcaaa atcagtttag
    43081 cggggcttcc ttttgttaaa tcgcgcatct tttaaactcc ttatatcttt aaaatttagt
    43141 tagtagtata tagcgtttat cctgagaata ccaattagaa atcaatgata atttatgaaa
    43201 ctccataaaa agaagccaag aattgagtca aagaatcaac aacttggcct ggtctgtaaa
    43261 ataagggaca tccacgttta tctatcacct taatattgtc taatctcact tggtaaaagg
    43321 atcgtttctc tcgtaccgtc atcataggcg tatacttgag caggaaattg gttcgaatag
    43381 gcaaacggca aatcaatatc catttccaca ttgcttcctg cttgagaaaa atgcatcgtc
    43441 acttttccac gattttcgat caaatcaaag gttaatatat tttctaatgg aatgactccc
    43501 ttaagatcta ggtcaataat aaaccatata ctgtcaatca attcatctgg caaacttgat
    43561 acgacaccaa ctgaagcgta acggttgcgg ctgctatcaa aactttcaaa catctgttta
    43621 acctccttcg aatcaacgaa tgttttattt ttataattaa tcctaggata aactagaaat
    43681 acttacttca acgagggttc attctaataa agaatcagga aaaatgcaac aataattgaa
    43741 tacttttttt caaagtataa atttttataa aggtacgata aaagtatgcg aggaaaagct
    43801 tggtaaatta ggatttttcg tttgtaaagc catttacaaa agtggaagcc ccatatgaaa
    43861 ataaacgatt agaaataaaa aaggcgtgtt aaaagctgct gacccgccgc ttctaacacc
    43921 acctgattgt ttcagtatta ttcttctgtt gaaccgatca cttctggttc gccaccttca
    43981 cctgtgcttt cttcttcttc actttgagcg actacagcag cgatttgctc ttcactgtcg
    44041 gtcacgaatt tgtaatcgtc gttttttgga agatcggcta ctgtaataga atcacctaat
    44101 tccaagtttg tcacgtcaac ttcaattcgt tcaggcaatt tgtctggtgt agcagatacg
    44161 actactgtat acaagttttg agctaacact ccaccagatt tagcacccac tgattcgcca
    44221 acaagaacga cttctgtttc gacttctgtt tcttccgaca tgtttacaga tagaaattct
    44281 gcatgttcga aatgattggt aaaagtgttc gtttggatct tgtgaaccaa tgtattgact
    44341 ttttgtccat cgatgtccat cgtgatgact gtgttcgctc catgttcacg caacaatttg
    44401 cttagtgtca aaccatcgaa tgagataggg gtactttcta ctttataccc ataaacaaca
    44461 gctggaactt tcccttcgtg acgaagtttg tttcttaatg aacggggacg tacttctctt
    44521 ttacttactt ctaatgatac tgacataacc aaaattcctc cttaaaatgt gactgtctgc
    44581 tttggtaacg gacagatttt atttaagtga attctaaagg ctaatctcgt gcacatcatc
    44641 gaaggcaggg cgcttaaaaa agcgcaaaag gagagatgcg cgcatctccc cttagaaagt
    44701 caggattcaa cttttctcca ccaggtcatt acgctgtgta tgagaaatcc aattcacttt
    44761 actatttaac cgtaacgtga actgttaatt aagtcaagga ataactatga tgatgtattt
    44821 gcaagcaaga atattcaagg tataattaat tagtagtaat aagaaaggaa acagcatgcg
    44881 tttagataaa ttaatagaag aaaaattaga aacgacacgc aaggaaatga agcggctgtt
    44941 tgctttgaag caagtgatga tagatggcac agtcgaattt cgacaaaatc gaaatgtaga
    45001 tagtttactg catcaaatcg aagtagcagg tgaacactta gaaacaaatg agtcctatta
    45061 tcttctcaat aaacctgaaa aagctgttac agctgtatca gatccagaaa agacgacagt
    45121 aatcgatctg attgcaagtg ccgatcgttt ccaaccatta tatccagtgg gaagactaga
    45181 tagagataca acaggactat tgctgatcac ttcgaatgga caattgggat atgaaatgct
    45241 acttccagaa aaaaaggttt caaagactta tcaagtagtt gtgaacgaaa gggtgacacc
    45301 ggcagacgta acagcatttg aaaatggaat cgtattcgct gatgggtatc aatgtaagcc
    45361 ggctgattta aaaatactca aagcagacaa gcaccaaagt acggttttat tgacgatcca
    45421 agaaggaaaa ttccatcaag tcaaaaagat gttcttagcc caaggaaaga aagtgaccgc
    45481 attgaaacgg ctaagcatgg gaccattgga attagatgaa cagctaggag taggcgagta
    45541 tcgatcgttg acattagcag agatgaaaaa gttaagtatt tattttaaat aggaggtcaa
    45601 aaagatgaaa tataaaactt tattgtttga tgtagatgat acattgttag attttcaatt
    45661 aactgaagcc aatgctttaa gtgctttgtt tgcagaacaa ggaatcacat tgacaccaga
    45721 aatcgaaacc agctataagg ctttgaatca tcatttatgg caggagtttg aaaaaggcag
    45781 actatcacga gaagaaataa taggcagtcg ttttgggtta cttttccagc aatttgggaa
    45841 aacagtagat agtgatcaaa tggaaaaacg ctaccgccac tacttgaacc aaggtcatga
    45901 tcttgttcca ggaagtctag aaatcctgaa aaaggtccat ccgcatgctg atctttatat
    45961 tgtgacgaac ggtgtgtcgc acacgcaaca tcggcgatta acagatgcag gaatgcttga
    46021 ttacttcaag gatatctttg tctcagaagc tgtcggagcg caaaagccga tgaaagaatt
    46081 ttttgatcat gtcttttccc acattcctaa ttttgataaa aagcaaactg tgatcattgg
    46141 tgattctttg acttctgata tcaaaggagg aaatatggca gggatcgata cgatttggtt
    46201 caatagaaat aaattaccag aaatcgaaga aatccagcct acttatcgaa tcgattcatt
    46261 agaggaactt tattcattat tggaaattga aaaggattaa ttttcagaaa aatatagcat
    46321 tttcgtgttt tttcgctata atagattaga atgaaaaaac ggatacgaaa gaggttttag
    46381 tcaatgacaa aaagcaagcc aattatcatt ggtgtgacgg gtggatccgg aagcggaaag
    46441 acaagtgtca gccgtgcgat tttcaacaac ttcccggacc attccatcat gatgcttgaa
    46501 caagattctt attacaagga tcagagccat ttgagttttg aagaacgatt gaacacaaat
    46561 tacgatcacc catttgcctt tgataatgat ctgctgattc agcatgtagg cgacttactg
    46621 aactataaag ccattgaaaa acccgtgtat gactatgtag cgcatacaag aagtcaggca
    46681 acgatcattc aggaaccaaa agaagtgatc attctagaag gaatcctgat tttagaagac
    46741 gaacgtctgc gtgacttgat ggatatcaaa gtatacgtag atacagatga tgacattcgt
    46801 atcattcgtc gtatcaaacg ggatatggaa gaacggggac gcacattgga ctccgtgatc
    46861 gaacaatatt tgacagttgt taaaccgatg tatcatcaat ttatcgaacc aacgaagcgc
    46921 tatgcggata tcattgttcc agaaggcgga gaaaaccacg ttgctattga tttgattaca
    46981 acaaaagtag ctagtttctt aaaccataaa tagtgcgcag cgaaacagtt gaacggactg
    47041 cgaccgtttg aaaagcaagg attctgcttt ttgaacagtc accagccaac tgttttttta
    47101 tttataacaa gaggttgtga aaacagcatc ttgacctaag tattaaaaag aagaaacgga
    47161 aaatagctgt ttatatttta ccgttttttg agctaatacc gaaggtcagc tgattgagca
    47221 ccgtgaagta gaggttgtaa aaaagctgtc tttgcatcaa gcgataagag catccaaata
    47281 aaacagctcc tcacgttttt cgttgggttg ggcttattat cgtagatgca agcttttgaa
    47341 caccgtttaa cgagaggttg taacagaagt ggtcagatgc aataaataag aagaaactta
    47401 cgaaaattat ttctcgaatt tgtgtgagat ttcgacttat ttttttgaag aagctctttt
    47461 gtcgcacccc c
//
LOCUS       DAFELK010000017        44081 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFELK010000017
VERSION     DAFELK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.018"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..1033)
                     /locus_tag="LP433_001173"
     CDS             complement(<1..1033)
                     /locus_tag="LP433_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2005351.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVL"
     gene            complement(1062..1379)
                     /locus_tag="LP433_001174"
     CDS             complement(1062..1379)
                     /locus_tag="LP433_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2005352.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(1405..1725)
                     /locus_tag="LP433_001175"
     CDS             complement(1405..1725)
                     /locus_tag="LP433_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2005353.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(2189..3604)
                     /locus_tag="LP433_001176"
     CDS             complement(2189..3604)
                     /locus_tag="LP433_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2005354.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(3621..4937)
                     /locus_tag="LP433_001177"
     CDS             complement(3621..4937)
                     /locus_tag="LP433_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2005355.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(5087..5785)
                     /locus_tag="LP433_001178"
     CDS             complement(5087..5785)
                     /locus_tag="LP433_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBL2005356.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(6074..7030)
                     /locus_tag="LP433_001179"
     CDS             complement(6074..7030)
                     /locus_tag="LP433_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2005357.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(7143..7976)
                     /gene="msrA"
                     /locus_tag="LP433_001180"
     CDS             complement(7143..7976)
                     /gene="msrA"
                     /locus_tag="LP433_001180"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2005358.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(8151..9785)
                     /locus_tag="LP433_001181"
     CDS             complement(8151..9785)
                     /locus_tag="LP433_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005359.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(9772..11640)
                     /locus_tag="LP433_001182"
     CDS             complement(9772..11640)
                     /locus_tag="LP433_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005360.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVL
                     YYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIK
                     FVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNN
                     DITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPIS
                     LLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAK
                     VIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKY
                     KAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENK
                     IEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            11606..13243
                     /locus_tag="LP433_001183"
     CDS             11606..13243
                     /locus_tag="LP433_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005361.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(13388..14128)
                     /gene="truA"
                     /locus_tag="LP433_001184"
     CDS             complement(13388..14128)
                     /gene="truA"
                     /locus_tag="LP433_001184"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL2005362.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(14319..14954)
                     /locus_tag="LP433_001185"
     CDS             complement(14319..14954)
                     /locus_tag="LP433_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBL2005363.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(15101..16342)
                     /gene="sstT"
                     /locus_tag="LP433_001186"
     CDS             complement(15101..16342)
                     /gene="sstT"
                     /locus_tag="LP433_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBL2005364.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            16540..17538
                     /locus_tag="LP433_001187"
     CDS             16540..17538
                     /locus_tag="LP433_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005365.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            17551..19569
                     /locus_tag="LP433_001188"
     CDS             17551..19569
                     /locus_tag="LP433_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBL2005366.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(19629..20345)
                     /locus_tag="LP433_001189"
     CDS             complement(19629..20345)
                     /locus_tag="LP433_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBL2005367.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(20572..21114)
                     /locus_tag="LP433_001190"
     CDS             complement(20572..21114)
                     /locus_tag="LP433_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL2005368.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(21119..21346)
                     /locus_tag="LP433_001191"
     CDS             complement(21119..21346)
                     /locus_tag="LP433_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL2005369.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(21425..23305)
                     /locus_tag="LP433_001192"
     CDS             complement(21425..23305)
                     /locus_tag="LP433_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL2005370.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(23494..24108)
                     /locus_tag="LP433_001193"
     CDS             complement(23494..24108)
                     /locus_tag="LP433_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2005371.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            24250..24810
                     /locus_tag="LP433_001194"
     CDS             24250..24810
                     /locus_tag="LP433_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2005372.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(25115..25429)
                     /locus_tag="LP433_001195"
                     /pseudo
     CDS             complement(25115..25429)
                     /locus_tag="LP433_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(25683..27318)
                     /locus_tag="LP433_001196"
                     /pseudo
     CDS             complement(25683..27318)
                     /locus_tag="LP433_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(27873..28436)
                     /locus_tag="LP433_001197"
     CDS             complement(27873..28436)
                     /locus_tag="LP433_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBL2005373.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(28451..29494)
                     /locus_tag="LP433_001198"
     CDS             complement(28451..29494)
                     /locus_tag="LP433_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005374.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(29627..30031)
                     /locus_tag="LP433_001199"
     CDS             complement(29627..30031)
                     /locus_tag="LP433_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL2005375.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(30264..30899)
                     /locus_tag="LP433_001200"
     CDS             complement(30264..30899)
                     /locus_tag="LP433_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBL2005376.1"
                     /translation="MIFLQKYGFYFLLLGVMSDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILVVATVGLYGIGDCIFT
                     GLFSINTNESSCNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(31165..32217)
                     /locus_tag="LP433_001201"
     CDS             complement(31165..32217)
                     /locus_tag="LP433_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2005377.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(32230..33168)
                     /locus_tag="LP433_001202"
     CDS             complement(32230..33168)
                     /locus_tag="LP433_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL2005378.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(33619..34269)
                     /locus_tag="LP433_001203"
     CDS             complement(33619..34269)
                     /locus_tag="LP433_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005379.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(34369..34878)
                     /locus_tag="LP433_001204"
     CDS             complement(34369..34878)
                     /locus_tag="LP433_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBL2005380.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(35079..35948)
                     /locus_tag="LP433_001205"
     CDS             complement(35079..35948)
                     /locus_tag="LP433_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2005381.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(35968..37089)
                     /locus_tag="LP433_001206"
     CDS             complement(35968..37089)
                     /locus_tag="LP433_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBL2005382.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(37091..37486)
                     /locus_tag="LP433_001207"
     CDS             complement(37091..37486)
                     /locus_tag="LP433_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2005383.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(37505..38311)
                     /locus_tag="LP433_001208"
     CDS             complement(37505..38311)
                     /locus_tag="LP433_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2005384.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(38304..39092)
                     /locus_tag="LP433_001209"
     CDS             complement(38304..39092)
                     /locus_tag="LP433_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2005385.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(39106..39582)
                     /locus_tag="LP433_001210"
     CDS             complement(39106..39582)
                     /locus_tag="LP433_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2005386.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(39654..42311)
                     /locus_tag="LP433_001211"
     CDS             complement(39654..42311)
                     /locus_tag="LP433_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2005387.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(42330..42734)
                     /locus_tag="LP433_001212"
     CDS             complement(42330..42734)
                     /locus_tag="LP433_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBL2005388.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(42966..43223)
                     /locus_tag="LP433_001213"
     CDS             complement(42966..43223)
                     /locus_tag="LP433_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBL2005389.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(43348..43680)
                     /locus_tag="LP433_001214"
     CDS             complement(43348..43680)
                     /locus_tag="LP433_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005390.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT        13844 a         8731 c         6734 g        14772 t
ORIGIN      
        1 ctaagaccat tggtgtcaaa ataaatggaa tgaacatgat cgggttcaac acgataggta
       61 acccaaacat cgttggttca ttaatattga agacacctgg cgcaatcgac aagtttgtta
      121 caaccatata tggtttgttt ttacgtccta ctaaataaat agctaacagt aaacctaaag
      181 ttgcacctgt tcctcctaag ttgacaaagc tgtcaaagaa aggtttgttc acgataaacg
      241 gtgcgctatg tccagctgcg attgcattaa cgtttgcttc aatggctggc gcattgattg
      301 tttgcatcaa aggatcgacc atattcgctc cgtgtaaacc aaagaaccat aagaatggtg
      361 tgataaatgc aagcagtaag gcagatggat aagagtttgc aagtcccata aatggttctt
      421 ggaccactgt atagaaagaa cctacgatat catcaacacc gaatgcagca aaaattgcag
      481 caactaaagc aaacgcagag atagtgatca ttgctggtag taatgaagca aatgcttttg
      541 caactgccgg tggcacacca tcaggcattt tgatgatcaa tttttcattt ccgcttaaac
      601 gtacaaagat ttctgttgaa ataatcccaa caataatagc aataaacaaa ccgtttgagc
      661 tcatacctaa tgctccgcct aaagcgaaga aagagcctaa agaaatcaca cctgcggaaa
      721 caccgtcttt tcggtagccg ttagctaaat gataagcaag caagaaagca atcaagacag
      781 aaagaatggc aaatgtaccg ttccaagcag cagccccgaa tcctttccat gattcaccac
      841 caaaaattga gttcatcaat tcttggaacc cgggaatcgg taagttattg atcattactg
      901 ctaatgctcc taagatcatt aacggcatac tcaccataaa tgagtcccga atcgcaacta
      961 aatgccgttg tgcaccaatt tttgatgcta caggtataaa atgtttctcc ataaatgcaa
     1021 caaatttatc cataaatctt ccctcttttc tttactgtag attacgcgtt caatcgacga
     1081 tacagatcaa tgatctcttt tgctaaatct gtaaaagcta tagatgtcat cagatgatct
     1141 tgactgtgga ccgtcaaaag cgtgacttca acgtgatttc cttgtgcttc ttgtgtcagc
     1201 atctctgttt gagagtgatg tgcttggact aaagattcct ctgcatcttt gattttttca
     1261 tctgctaaag tgaaatcacc ttttttcgca gcagcaatcg cttccattgc atcgcttttt
     1321 gcatttccgc caaacatgat cagacccatg atggcttcta gatttttttg atcttccatt
     1381 tattgtatcc tccgataatt tttattattt gtttattagt ttttctgctt ggtcgagtac
     1441 tttttcacca ttcatcatgc catagtcagc catattgatt acatctaaag gaatgccttt
     1501 aggtgctagc ttttcagcaa attgattttg cataaagcgt acttgcggtc ctaaaagtaa
     1561 aacgtctaca tttttagatt ctagttgatt atccgcatct gaagcagata cagcaaagat
     1621 gtctgcttcc attccttttg cttctgctgc cttttgcatt tttgtgacta ggagacttgt
     1681 actcattcca gctgaacata caagcatgat tgttttcttt tccattttaa acacgttcct
     1741 ttctatactt acacttgtat ataagcaagt agcgtgccaa ctttaaaagc gctttaaaaa
     1801 gttgatatca tcacatttaa ggtctatacc aagttgcata cacactaaaa aagaaagcgc
     1861 acactaaaca cacaaattaa tttttattac cttttttctt ttaacgtgca caaaaaaagt
     1921 tgtgacacaa aacttgtcac aacttttttc aaataaacgg tattcaaaag cttgcatctg
     1981 cggtaataag tccaaccaag ttaaaaacat aagatgttgt ttttactttg ctattcttat
     2041 tacttgatgc aggacagctt tttcacaacc tctcaataaa cggtgttcaa tcagctgacc
     2101 ctgggtatta gctcaaaacg ctggattcac aacctctttt atttcaaata accagtaaat
     2161 acaatgaaca tctacaaaaa acttctattt atttatagat ttcgtcaggc aaatccaatt
     2221 ctctcttatc aatcaaagtc tgataccacg aagcagattt tttcaatgtt ctgcttcgtt
     2281 catcgttcaa ttcgattcga actaatccat atcgattctt aaatgcattc attggtgaca
     2341 cacagtcagt gaatgcccat aacatatagc cttcgcaatt tgcgccttct tctgttgctt
     2401 tgatcaagta atgcaaatgc tgtccgataa attcgatacg gtaatcatct tgcacgattc
     2461 ctttctcatc catatactgt tcttcatatt ctcttcccat accgttttct gttatcagcc
     2521 aagggatatt atgataattt tcttttagat acatggctat atcatacatg attttcggat
     2581 agatttccca tcccctggaa ttattcattt tcttcccagg taaatcaaag acttcataat
     2641 atcgttcagg atggaaaggt gtctcttcat tccattgata acgaggggcg cgaacgcgtt
     2701 taggataata ttgattgatt ccaaggaaat ctactgtatg atgctgaatc gtttctaaat
     2761 cctctgttgc aggatcgaaa taaatcgatt gtttttgaca caactccagg aactcttctg
     2821 tgtagtatcc ttttaccatc ggatcaaaaa atactcgatt ataaaacaaa tcatacatat
     2881 aagcagcttt ttggtcttct ggagaattgg atcgagcata gaccatttca ggatttaaaa
     2941 tacagccaat ccttccacca taatttccgc tgcggtaaat ctctactgct ttagccgttg
     3001 ctaaaacttt atgataattc cacatcatcc acttttttgt gttttgttca tgcggccagc
     3061 gaacagcatc caaatagcaa cgcgtttggg gaacgattgg ttcgttgaat gtaaaccagt
     3121 tttttaccct atcaccgtaa cgatcaaagg caatttgagc atacttagca taaaaatcaa
     3181 ctacttttct tgaagaccag ccatcatatt tttccaaaag aaaagctggg acttcataat
     3241 gttccaaaca aatcatcggt tctacgtctg cttcgatcaa agagtcgatc atttcactta
     3301 tatgctgagc atattcttca tctactatac agttctcata atcagtaaaa aaacgagccc
     3361 aattgataga agtccgataa tgtgtcagat ggatggattt catcagatcc acatcctgct
     3421 ggtattgttc cataaaatta gttgctacgg ctgggccata cccattatgc caaacaaaat
     3481 gttcattttt ataccagcta tctataaacg aatcctgtcc ttcttttttt cctttccaac
     3541 cttccgtttg ccaagcagaa gatgcagcac caagaataaa attttttgga atagtaattt
     3601 tcatgatttc ctcctgtttt ttagatccca tcattttcca cacgatttgc tacttttaca
     3661 aatggcagat agatcaaaat agaaacaata atacaaacaa gttgcgtaat aactgcaccg
     3721 atatttcctg ctgttgccag ataagcattg acgatcggcg gcattggcca agggaccatt
     3781 acaactgctt tcgccgcaaa tcctaaagcg gttgcaaaat aaccaatcgt tccagtgata
     3841 agaggcgtta agataaacgg aatagctaaa attggattca gcatgatcgg cataccaaaa
     3901 ataactggtt cattgatgtt gaagatccca ggagcaaggg ataacttggt gatttgtttc
     3961 atatcttccc gttttccaac taacaatact gcaatcagta aaccgatcgt gactccagac
     4021 ccgcccatac tcatatacat atcccaaaat ggcatagtaa taatgttcgg tacttctttt
     4081 ccagcttcaa aagcttccgt atttacagca attgccgcta aaagcaacgg ttcccgtatc
     4141 ggcttcacca tttgatttcc atggatacca atcacccaaa agacttgcgc aataaacatc
     4201 aatagcaaaa tacccggtaa cccttgtacg acaccttcta atgggcgttg tacgacattg
     4261 taaatgatat cataaaggta cattcctgta agttctttga tgataaatcc cgcagccgcg
     4321 atacccgata cagtcagaat cgtcgggaat aaagcagaaa aactagcaga aacattcgtt
     4381 ggcacggtat caggcattct cagctgtagt ttcttctgtt tcctcaacca gcaataaagt
     4441 tcaatagaaa ggatggagac caacattccc aaaaataacc ctttcgtatc tgtatattgt
     4501 ttagccaata cgttttctac tataacagtc tgattttcat tcactaattc ataaacagtt
     4561 ggattaacag ataaataaga catcactgcg atgataccag ggaatacacc atccacttta
     4621 ttcagcttgg ctaattcgat ccctatcaga aaaacagcat agatggtcaa gaaacttagt
     4681 gtgacatagc tgatggcaga tgcgataggc tttaattctt ctaaaaaacg caagaaactt
     4741 atctgtgcta agccattttc cgagtcaaag accattgctg aaaacaatgt gccaaaagca
     4801 cccgtaataa ttaccggaat caatgcagca aatgcgtttt ttatcaccat gatatacctt
     4861 aaattattga ttctcgttgc cacgttccct aaaacattgg ctaatttatc cataaaactc
     4921 attccagatc ccctcattcc tgcttcttct ccttgacgtc atctcttttt gtctattagt
     4981 cagcgcttac atttcgatga acagaaacta tttactcctc ttttttacca aatataaaac
     5041 aaaaattcat ctgatgtatt tatcataaaa tacatcagat gaactgtcaa ttagtttctt
     5101 tttctcctat tattttctgt aattctctcc gatttattgc catatggaca gtcattgcat
     5161 caaacgcagc aagtgcattc cgcctttcga tggcctgaac gatctctgta tgaatatcga
     5221 tcgtctcgat tttcagatgc tggatatcat aatttttatt aaacaaagca attgattcat
     5281 taatgattgg gataatatgc agcaaggcta cgtttccgct agcttctgca atcatcgtat
     5341 gaaaatcgat gtctaattga acatgttctt gtgtgccttc tcgaaaagaa gtttcaatct
     5401 tttgcgttaa ttttttcatt tggacgattt gattcttcgt tgcatattcc gctgccaaac
     5461 ctgccatctt aggctccaat aaatatctca gttcaaataa gtctcgtatc atccgatcct
     5521 gatcttcaat caaagaaaaa ccgagtgggt cattggcaat ccctcgctta tcactgacaa
     5581 atgtccccgc tccttgccga acttcaagga tattcctgga agctagagcc cgcacagctt
     5641 ctcgcaccgt gcttcgcccc acctctaaat aatcggacaa ttcatattca ttcggcagtt
     5701 tatctcctac ttgcaactgc atttccttta aatatctaag gatcttgtca gtagttactt
     5761 ctactagggt tttattttct tccaaaccac atacctcctt ttcatctgat gtattttttc
     5821 gtaattatta taacacgttt gaatcatctg atgatttttt gtatacaaaa ttgattaatc
     5881 cgttcataga catacaaacg aagaagatat ttaccataaa aaagactagg ataaaattca
     5941 ctcctagcct tcgatcattt ttattttgaa cgacaaaaaa tatgatgttc aataacagac
     6001 gatcttcatt cgattcttga tgtcatcttt tgtttttttt aatatatgga taaaaagttt
     6061 gattacatcg tttctattct agaatttggt cgattctcaa ttcttcttct ggtgagaaat
     6121 ctaaattatc catcattcga acactttctt gtaactgact taaccgactt gctccgacca
     6181 gtacacttgt aacagatttt tgtcgcaaat tccatgcaag ggccatttgc gctaatgatt
     6241 gtcctcgtga tacggcgatt gtttgcagtg ctttgatttt ttccagagtt gatccaactt
     6301 gttcttctga aaggaatggt atttccttac gatgtgctct agaatcttca ggaataccat
     6361 gtagataacg atttgtcagc aacccttgag caagcggact gaacgtgatt gcccctagcc
     6421 cttcttcttc taatactgga gatagatcgt cttctagtag tgcacgagaa aacatattgt
     6481 agcgcatctg atgaataatg aacggtgctt cctttctttt taaaatttca gtcatttttt
     6541 ttgtatcttc tccattatag ttggatatac caatatataa tgcttttcct tgtcttacaa
     6601 gttgcatcaa agcttctgct gtttcttcca aaggtgtatc agggtctggg cgatgatgat
     6661 agaagatgtc aacataatct agccccattc tttggagact ttggtcacaa cttgaaatga
     6721 tggatttacg agagccccat tccccatatg gcccttccca catatgataa cctgctttgc
     6781 tagaaataat cagttcatca cggtaggctt gaaaatcttc tctaaaaata cgcccaaagt
     6841 ttttctctgc agctccagca gggcctccat aattattcgc aaggtcgaaa tgggtaattc
     6901 ccatgtcgaa tgcgcctctt aaaatctctc tttgattatg gataggatca taatcaccaa
     6961 aattttgcca taatccgaga gataaaatcg gtaatttcaa acctgaatga ccggatttac
     7021 gatattccat tttttcataa cgtgcactat ctgcaatata caatttttct cctcctcatc
     7081 aaatcttttt aaaacgcttt cttttttcta tttttagttt actacatttt aaagaaaagg
     7141 agttaatcaa aatgattttt tcgtatattt ttttgccatt tgttttttac tcgttgatag
     7201 atcagaaatt gattacgtgc ttgctggatt tttttataac gtttcggttg ttttttgtaa
     7261 aattgctgat gatagttttc tgctggccaa aacgtaccgg ctggttcgat ttttgtgacg
     7321 attggttggt ggaaagttcc tgaactgtct agtttctgtt ttgattgttc cgctaattct
     7381 ttttgtcgtt cgacttgata aaaaatcact ggacgatatt gcttccctct atcttgaaat
     7441 tgtccaaatg tatctgtggg atcagtaatt tgccaataga ttgtcagcaa ctcgctataa
     7501 cttatttctc ttgtgtcata aatgatctcc acagcttcca catgacctgt gtaaccacca
     7561 cttacttgat cataatttgg tttttcaaca tgtccgcccg tgtatcctga caaaacagat
     7621 aggatccctt ttttcgattc aaacggctcg accatacacc agaaacatcc ccctgcaaat
     7681 actgcacgtt cttgatagtc agcatcttgc atggcatgct tggaaaagtc atatttttgc
     7741 tccttatcaa atccttccgt aatcaataaa taaaagtcca ttacatcagg cgtcagattc
     7801 attcggatag ctaatggacg tagtgttgct tctagttttg ataactgttc tttaacggat
     7861 atattttctc ttatgtcatt ctttgtctga atcaatactt ttcgttccca atctcgtgta
     7921 ttcggattca aaatcagatt ataaagtgtt tgaatgaata tttgttcctc atccatagat
     7981 tctcctcctt tccgaagaag acaagctagt gactttagct gtaatttatc ataaagtgag
     8041 gaaataagcg attacttcat ccccctacag atttttcgta taaaaaagag agaatcctta
     8101 tcgacagatt ctccttttta atcaatttat tttataaatg aaaagttaat ttacctttta
     8161 tggaaaacta ttttaaaaaa taaacataaa tatgcagtta atgtaacaag ataagaaata
     8221 atagtcgtta ctgtataact tgtgcttact ttaatatcag caactccttt gactccgctt
     8281 atttgtacca atccattagc attcacctgc tcctttacag gttgatgatt tatttctaca
     8341 ttcgttccta aataagcata tacaggaagt gtgattactt ggctcttctc attagttact
     8401 ctatatatga tagaactacc agttgtttta taaggaaggt ttacccattg actgccaatc
     8461 tttgcttcgt gttttattat atgctcctta ttctccaatg aagcgatagg agaataatca
     8521 tataaaaaat aatccattcc tttagtggta tacgcctcta ctgtttcttt gtttacaaca
     8581 atatgtcccg gctgagaaat tattttttga ttgaaatttt ttttactaga aacagttaaa
     8641 gtgattaata acaaaacagt cataaataaa taaaatagtt ctcttgtctt attgtatctt
     8701 ctatttttga aaaatatcat cgttaatatc agagaagaga atattatttg caagcttaag
     8761 atccgccaag gaaattgtaa caatttggct ggcgtatttt gcagaagata ccatggcacc
     8821 aaactagttg tagctagcca agtcaaacac gtaccataat aaatcttttt ttctatgttt
     8881 gttaattttt taaataaaat caggggaata cataaagata acagaccaac tagtcccatt
     8941 gagtaagtag ttaagtcgtt gttcatagct tcagtcagac tatcgaacac attagatgca
     9001 tgagcatata aatttgtcac gctaggtttg ttgatttttt ggtagagcat ttgttcaaac
     9061 atcggatacc aaaaagcact cgtcagaacc aatgtcattc ctgccgcact aaataatttt
     9121 ttaaatatag caataaaatc tgcattcttg aaacctttag aaaccaaacg aataaaaata
     9181 aaaatgataa ttaatgctgt actcattaat gttgatagta catggctgta cactagcaaa
     9241 ctcatactca atgctagctt tacagacgga tacttttctt cttttccaga gatgatttga
     9301 taagcataaa ataatacagg gataacaagt gttattgcga tagcttcggc aattgcggaa
     9361 cgatagtaga tgtctactgt ccgataagca gagaaaatat agagacaact aaataaaaat
     9421 gccgcttttt tttgttttaa aaaccgctcg ccataatgat aagctacgag tgttgtacac
     9481 aagttcaata accaaacgta aataatatag cttacaatca aattttttgt catccaatat
     9541 aacattacag ctggaaaaaa agtcagaaag ggataaaaat aatttacacc atatccagta
     9601 taattgaatg tctcataatt aatcggactg gtaaaaatag tcgataaccc cttgattcga
     9661 gataagtgaa aagaaagatc tccagtggta taaatactct gtgtattttt gaaaaagatg
     9721 aaagaatata tactactaac tataattaat ccactcaata ttactacttt tttatttatt
     9781 ttcattcttc ttgtttatct cctttttagt cacatatcga gaatctttca acttattagg
     9841 tgcaaatcgt ttaaaacttg aatacaccac taaacaataa gtcagaatac tgatccataa
     9901 agccatgaga gcagttggag tatattttgt tgtaatttct atcttatttt ctccagcatt
     9961 tacatccaca ttcactaagc catgtttttt ataagagtca tttacgactt taccgtttac
    10021 ttttacctgt gtacctaaat aagcatatac tggtactgtc actttttgct ttttgttgct
    10081 tgccactgtg taagtaatgt tattatctgc agctttatac ttcccttttt cccacgattc
    10141 tcctactttt acttcatgtt tttctaagtg aggcctttct tttatcgctt ctgttggggc
    10201 gtaatcgtat aatcctccca tatctgatgt tgtataacgt gggagtgttt cttcattgat
    10261 aacaatatga ccgtgttttg attggataac ttttgcgtaa ttttcttttg ctgctataga
    10321 cgtgacgagt agaaacacca cagtagcgcc aatgattaac catgaatatt ttttattcat
    10381 agtctttttc ataaaaacaa gcgttatgat cattgaagaa aaaaagattt ggatacctaa
    10441 gatacgccaa ggaaactgga gtaagcttat cggtgttttt tgaaacaaaa accatggaaa
    10501 taaattagtt acgcataccc atgtagaaac tacgccaaca tagatgattt tttctttttt
    10561 ctccatttct ttcagtatga ataaaggaaa aatcaacgca accaatccta ataaccccat
    10621 agtgtatgtt gtaatatcgt tatttaacgc ttgaatgata ctatctgaaa tagaaagtgc
    10681 ttctagctgc aaatctgttt tgaagggact gtgtatttct tgataattca tctgctgcaa
    10741 cataggatac caaaaatagc tagttaatgc acaagtcaaa aaaacagcct ttactaaatt
    10801 cacgaccaca aattttatat cgttttttat ttgcttgctt aaaaacaaac gaactataat
    10861 catacaagca atcaatgcac tacacaatag tgtagttaag acatgagtat acacaagtag
    10921 acttatactg acagataaag cgatgacttt tttttctcta ttgaatatca atccataagc
    10981 ataatataaa acagctggga taatcgtaag agcgattgct tctgcaattg cggatcgata
    11041 atagatatca actgttcgat aagttgcaaa agtatataaa caactaaata aaaaagcagc
    11101 atctatcttt ttaaaaaact tttctccata ataaaaacta atcagaatcg tacaaatatt
    11161 taataaccaa atatatagaa cataacttaa tattaagtta tttgaaattc cataaaaaac
    11221 gactgcagga attattgtaa gaaaaggata aaaatagttc agtccatctc cataattgtt
    11281 aaatgttgta tagttgattg gcccttcaaa aatagaagat aaccctttga ttcgtgaaag
    11341 atgaaaagat aaatcacctg ttgtataaat ttcttgagca tttctcataa aatttactga
    11401 atataaagta ctaagtaaga taagaactac taaaagaaat gcttttttac ttattttcat
    11461 agatttgttg ttctcctttt ttaattctat tttcagtata ctagaattgt ctttttttaa
    11521 taagttttgc gttaaatttt tcatagcact agtatgatat actagaaaag aatcaatttt
    11581 tattactttt aaataggaga aaaaaatgaa aaaaaacaaa aaccaaataa tagatatcat
    11641 ttttatgtta tttctaagtt ttgcttacgt catccctcta ttcatgtcta agggaatcta
    11701 tcatagtgtc aatcaggata cttactttca tttatctcga atcataggac tagataatgt
    11761 atggagttct ccagtaaact tcaataactt cgatcatcat ggaacaatga tgaatatttt
    11821 ttatccatgg cttactcttt atccagcttt tttattttat aaaatgatgg gaaatcttgt
    11881 tttaagttat aatatctact atttttttat cactttttta acaatggtcg tttcttattt
    11941 ttctatgaaa caaataaaaa acaatcgtta tatttcgctg ttattttcga ttatttatac
    12001 attttccgcc tatcgtgcca ttgacatatt ccatcgtgct tcattgggag aagctgtcgc
    12061 tttaacattt ttgcctttga tactaatggg gtgttacgaa atttatatta gagattacca
    12121 aaaatggtac tggttgtcta ttggcatgac gctagtagtg tatactcatt tactttctgt
    12181 cgctatggtt tctgtattta ttggaggaac gttgtttctt tctttttatt tttgggacca
    12241 aaaaatcgct agactcttaa gtcttttaaa agctaccgtc ctcacctttt ttttaagtgc
    12301 gggattctta attcctttta ttcaacaatc tagagcacaa gaattgaaag tcccactggg
    12361 aaaagaatta agtggtatgg ctcctagtga tatgctgaca catattttaa ataataacta
    12421 taacaactat actattggat tattcttatt tctcggattg attggtgctt ttatttttat
    12481 aaaaaaatta actgctgatg atttatttat tttctttctt ggtgtatttg ttcttttttg
    12541 ttcaaccaat ttatttcctt ggcaactttt taaccataca ccagttaaga gtctacaatt
    12601 tgtctggcgg ttaaatggtt tttcttcttt atttatagcc tatacgatga gtatagtgat
    12661 ctattatatt ttttctacta aaaataattc atggaaaata atggtcttta cgtttcttgc
    12721 actaatattg catctctcag gagtaagcaa ttctatccat gctaacaaag attcattaac
    12781 acttatagca cctgaagacg ctgttgctat agctgaaaat tacaatcata ctgattatgc
    12841 aaacaaagag tcaatctatc atcctgatat gattaataat gatcaatatt tactaggtaa
    12901 ccaggaaata aatccaacaa ctcattttat gagtaacaaa cttacaattg aattagataa
    12961 ttcgaataat aaaaatactg tcttgacgac acctatttat cgttataaag ggcaagtggc
    13021 ttctattaat ggcaaactag tacaaacaaa attatctaag tttggcacaa ctgaattaac
    13081 tattcctcca ggtataaata aagtcgttat tacttatcag tacacaaaac tagcaattgc
    13141 ttcaagatat ttatctatcg ttactttgat tttattttta ctttatcgat ttactttttc
    13201 taaacaaaaa caaccgagaa gagaagtaca acattctcac tagattttta tttaagaaag
    13261 actttttagc tgtacacata aacaggctaa aaagtctttt tttatatttc tttaatttgc
    13321 ttcatacatt atttaacatc gatatttata ctgtgaaaca tgcgtttcat ccattatcaa
    13381 agtattttta tcgataataa acttcatcca aaaacagacc ttgtgcaggg acggtttctc
    13441 ctgcatgttg ccgcactttg ctttcaaata tttcatcgat tgtttctatc ggcatggcac
    13501 ctgtgccgat ttctagtaat gtccccatga taatccgcac cattttatat aagaatccgt
    13561 ctccgacaaa agtaaaatga agcatttctc cctttcgttc gatagataat tcatcaatcg
    13621 tacgcactgt ggattttttt gattttttca atgcagaaaa accaatgaaa tcatgtgtac
    13681 ccactaattt ttcgcaagct gcattcagct tgtccatatc caactcttga gggaaataaa
    13741 agctgtggtt tcgctcaaat gctgaaggaa tcacgttgtt ccaaacataa tagctgtatt
    13801 ttttgcccac cgcattatat cttgaatgga agcgctcagg catttcttcg attcttttga
    13861 tgacaatatc ccgcggaagg taacgattca taaagtcgat catttctgcc agtccaattt
    13921 ctgtgtttgt tttaaaattt gctacttgtc ctcgcgcatg ggtgccagca tctgttcttc
    13981 ctgatccaat aatttctatc tcttcatttg tcatctgatg caatactttt tcgatttttc
    14041 cttgaatggt tttatcgtca tctccaagtc tttgccatcc tgaatatctt tttccgtcat
    14101 attcgattgt caacttgatg tttctcatat tttagtggct cctctgtctt ccatttggtc
    14161 ttctctctac ctttttaaga ttgtagcaca aaatatagct ccttgcttct ctaagacaga
    14221 agctatacaa gaaaactgtg gaaatatata tttcagaaaa acaaaaaaca gccaccggat
    14281 gaagtatccg ctgactgttc aatttgacgg ctcaagtttt actgtttgag atgcaagata
    14341 ctcaaccagg caatgggcac ataattaaag aaaaaactga ttctttggca aaaacctatt
    14401 ttattcagta atggccaaga atttatagaa ggaattcttg ccagtccata aatcgccgca
    14461 aaaagcaaac tgatcacaga cagtccaagg tataagtggc ttacgtccat ttgcccattt
    14521 tttcgataga tcaagaaaag aagaactgga aacaataaaa aaccactgta acctaaacct
    14581 gatccgatat tatggaccca tgtcgagaca ttccacgaag attcatgggt attgatactg
    14641 aacaaacctg taaagataca atcacctata ccatagaacg cgatggctgc tgtaactagg
    14701 gtagctaaca cacgagatgt actaacaaat gcagcataca atgcaggcaa tgacaggatg
    14761 aaaaagatcc ctgaaaccac agaccaaata agaaacgctt ttcttacagg actggaaacc
    14821 tctccaaata cactgatcac gctcttcatt tgatctaatt caggataata caatcctaat
    14881 acgtacggag tcaaaaaatc actcagcacg cctaataata aaaagaaaaa accaaattta
    14941 cgtaaaaaat ccatgatacg cctccaataa caattaccta tgcttttaat tgttattata
    15001 aacgacttta tcttgattta acagaaacct ctatttacac gaacatctat ataactcatt
    15061 aaaaactcga atcattttaa aaatactaaa tatctaacgt tcaacgttca cttaatccat
    15121 ctaaacaatc tttcaatttg attttttccc cacttctttt acgcgcgcct agctctccta
    15181 ttgcagtaaa caacagatca cttgacgaat ttaaggcagt ttccattgaa tcctggataa
    15241 caccgataat aaatccaata ccgacgattt gcatcgcgac atcattagag ataccaaaca
    15301 aactacatgc taatggaatc aataacagtg aaccgcccgc aacacctgaa gctccacaag
    15361 cagctaaagc agacaaaata cataaaagga ctttcaaaac aaaaggtgct tcaatcccta
    15421 aagaatgtac agcagtcaac gtcatcaagg aaatggtaat cgcggcaccg cccatattga
    15481 tcgtagcacc taacgggatc gatatggaat aagactcttt tgtcaatttc aatctttcag
    15541 ccaacatcat gtttatcggg atatttgcgg cagaacttcg ggtaaagaaa gcgggaagtg
    15601 cgctttcttt caaacaaaag aaaatcaatg gatagggatt ttctttaata aacaaaaacg
    15661 tgaggaatgg gtacacaact aatgcgacaa acagcatcgt accgatcaaa acaagtaaaa
    15721 gctgcagata ctctgccaat ccagcgattc cagtcgtagc aattgattga taaaccaatc
    15781 ctaaaatccc tatcggagca aatgcaataa tcacttgtac gacttgtgac aacgctatag
    15841 atatctgatc caccaactct tttgtcgatt ctgaacgtgc tcgaaaagct agtcccaaca
    15901 atacagccca gaataagacg ccaaggtaat tcgcatcaat aagagattga acaggatttt
    15961 gtgtgacatt cgtcaacata gtagataaaa cactttccaa actttgcggt gctttttcag
    16021 atactgtttc ttgtaaagta ataggaacag taaaaattga acttacaata actgctacaa
    16081 gtgcagaaag caatgttccc actaaatata agatcaaaat aggcttcacg aatgtcttat
    16141 tcccaatttt atgcttggca attgacgcca tcgtcaagaa aaaaaccaga ataggtgcga
    16201 ttgccttcaa gcaactgaca aacaacgttc ccaatattga aataaatgtc catgtgggga
    16261 aaaagatacc aaacaatatt ccgactaaaa taccaacaac aatacgttga actaacgaca
    16321 tatccaaaaa cttctctaac aaatgaccac cctttcacaa ttttaacaat cattgtatca
    16381 ttttatgcaa agaaactaaa ggtataattt tctaaaaatt ctaacaatac aaacaaccat
    16441 ttcttgctaa ttttgtactt tttctgtcta cacgttgttt tttgagatat tctaagttag
    16501 gatgttatta atgggcaact tatcaggaaa cgttttctta tgtttttgtc caattttttt
    16561 gtgaggtgtt tattcttgaa aaaaataaag aaggagagtt atggcttcct gacaatcttt
    16621 gtcgcttgta taatgatggt tttacagcgt atattgattt cagcagtcac tattcctaca
    16681 tatgcaacaa accctggtcg attctacatc tatacatttt tacaaacttc cgttgttatt
    16741 ggtgcaaatt tgatcccact ttacatgggt taccaatatc aaaaaatcgc ccgtttaaaa
    16801 gttttacatt atttaagtcg ttttgccttt atattcctaa tagccacact agtttgcaat
    16861 atcttttttt acgtacaagc tggcagcttg aatattcgtg attattggct tatcctaaca
    16921 cctatcagtc agaattactt tacttatgct gtttcttgta ctttgctttt ttgtagtatt
    16981 ccttatacag ttggattttt aaataaatta tcgaaaacaa caattaaata tctactatta
    17041 tttttaacaa ttggattagt tggctgctct actctattta ataaagaccc gtttgcatta
    17101 cagaatggac agagtatttt atggattttt tatttatttt taatgggtta tggtttgaaa
    17161 gaatggaact ggaaagaaaa ggtccgctat aagcttcctc aagtatttat cagcttgatt
    17221 gttttattcg gtttgattat tttgatgaca caaatttcac tcatcatcag aggaaataca
    17281 gatacagcgc tgaggttttc taaaccatat tctctcttcg caatgtatta tactttctct
    17341 tcgtttttat ttttagaaat gctatctgat aaattaggta taaaaggaag aggaaatttt
    17401 cttgctgtat ttttgattgt cactcaagtt atatgtaatt tccctttagt ttcttatcgc
    17461 gtatctacat ttatgaaacg tgaatttcca aactcaggga aggcatggct gataaatatc
    17521 gggcagtttt ttatttgata tttattagca gtgtccctcc tagttatctt tttattttat
    17581 atacaaaaaa tccgtttcat tcatcgtttc atcgaatact tcgcttttga ttcgattgaa
    17641 caattaactc agcgttggaa aaaaagaatt cattggcttt ttgttcataa aagttatttt
    17701 ttagttgcag cattttttta ctgctttacc ttcgtgcaga ttttcgtttt agaaccaaaa
    17761 gaaggttgga aagaaactat ccaggttgcc ttaaaaatat ttactcagcg acaagcaccc
    17821 atgatcctga caatcatcat tattatggga tttttcttct tactattgtt gatttccaat
    17881 cgtttttggt acgccttgac tgctaccttg atcattaact tactgctcac tatttcgaca
    17941 gtaatcaaaa tggaaatgcg ggaagagcct gtctttcctt cagatttaaa aatgctgacc
    18001 ggattgtcag aactattatc gatggttagc ccagtcttat taatcgtggg cggattgatc
    18061 cttctcctat tattgattac tagtattatt gtacaacgta gactacaaaa acagtattcc
    18121 ttgaagattc attggaaacg tcgatttatc agtatcgctg tattattagg atgtttttcg
    18181 ggtgtctttt tcattaatca caaaaattcg ccttctttct tgctgtttaa tttatttaaa
    18241 gtaaacaaga ctttctttaa ccagcaaggc gccgtaaaag ataacggacc agtcattcaa
    18301 ttcctaaaca atatcgacat taaaatcatg gaagaacctg ctggctattc gaaagaaaaa
    18361 attaatggaa taatgaaaaa gtacaacaca aaggcagatg aaatcaacca aacaagaagt
    18421 gactggttaa acaatcagac gatcgttctc aatttaagtg aaagcttcag tgatcctgca
    18481 cgtgtcccta atctgacagt acctacagac cctattcctt acatcaaaag cattataaca
    18541 gaaggaacag gaggattgat gttatccgtc ggttatggtg gcggaacagc taacatggaa
    18601 tgggaaggac tgacaggctt gagtatcagt aacctgtctg cttcgttagt tacaccttat
    18661 acccagctag tggagcgtca gaaaataagt ccaaatatta ccgatctatt cgatgaaaaa
    18721 atagccatcc atccttttac agctgctctt tatcgcagaa aacaagtgtt tgataaattt
    18781 ggttttgaca ggttctatta tttagacagt ccggataaat taacttatac ggataaaata
    18841 gaacaaagcc cacgcatatc ggatgattca gcatacaaag aaaccttgaa agctttacaa
    18901 agcaatacgg aaacgtcaca attcatccaa ttatccacta tgcaaaacca tatgccttat
    18961 gatgattact atagtgaatt gaactacact gctgaaggaa ctgctgtcat tcctaataga
    19021 agaaaagaat tacaaactta tatgcaaggc cttcactata ccgatacagc agtaaaaaaa
    19081 ttcatccaag aaatcgacaa aatcgataaa ccgattacct ttgtttttta tggtgaccat
    19141 ttacccgcaa tctatagtgg gaatgattcg aaaaaatatg gattagaaca gcaccagaca
    19201 gattatttca tttataacaa caagtatagt cgtgaacaag cagctacgtt aaataaagaa
    19261 gttgttgctc ctaataactt tggtgctatg gctcttgagc atgcgaatat caaagtaact
    19321 ccttactatg cgttgttgac agaagtatct aatcatctac ctgcattaac aattgatcct
    19381 acagaaagct tgtctaatcg ttttaatgga aaacaggtct ttgttacaga ggatagtcaa
    19441 attatccaag aaaaaaattt aactgagaaa caaaaagaaa ttctagaaga ttatcgtctg
    19501 atacaatatg atcttgttgc aggtaaccag tacagtgcaa catgggcgac acaaaaaata
    19561 aaagactaac aaataaactg agcaaggggt tgtgataaaa gacatgtcac aaccccttgt
    19621 ttatctcatt aatttgcttg tccataaacg atttgattaa agccattttt caattcatta
    19681 ttcgctgtct cgttgaagta aagataatta tcgggattcc cctgattttg ttgtgtcacc
    19741 aatacttttg gctgattttg ctgaaacccg aatagataga cgtgcttttt cagatatggt
    19801 tctgtctctg catcggaata gacggctgtg atttgatagt ctgcttgacc tgtcccactt
    19861 tctgaccatt ctgcagaaac aggcactcca ccaatagcca tcttccactc cccgttcaaa
    19921 atagcttgag ggactttaag accatataag tccacactca tttgattcgt ataacttttg
    19981 tattgttgtc ccattgtttg gccccatttg gtcataaatg cctctaattg tgcggatttg
    20041 tctgcattcc acagtgtttg ttcaacttgt tcgctgcttt ctgaagagga agatgaagcc
    20101 tctacagaag aacttgaagt agatgtttga gttgtttcag tcgttttgga agactctgac
    20161 gaagtagagg tatctgctgt ttctgtactt gctgcagttg acttgctctc tgtgctagtt
    20221 gttgtagtag ttgcaactgt tgctttcgct gtttcttttg ttgattcttt tttcgattca
    20281 ttcccgttgg tacaaccagc taacaaaaaa gctagaccaa ttgttactaa aatccttttt
    20341 ttcaattaaa aaactccttt cgattactcc cacttcttta ttctatcaaa taagcaatgt
    20401 gattttattg atttttcgta ttttctcatc aatctttcaa atcttctaaa aactgagaag
    20461 cacccgctga tgttgtctgt aatacatcag cgggtgcttc ttttatttta atcttcgtga
    20521 ttttccaatt tacctcacgc tttatatttg tatttgaaga aacatagact tttagtcatc
    20581 atcgtcttcc tcatccaaat cttgtcggac agtttttcct tggagtcttt gtacttggta
    20641 gatgatttct ttattgaaac ttaaaagttc aacaagcaat tgttgcaagc catatttttc
    20701 ttctttttca gctaatttga ttgcccgtgt gataaagaca ttttggaaat caaaatcttt
    20761 tgcaaagttt tccaacattg ttgaggctgg taaatatttg ttttgaccat gttcgtaaat
    20821 ttttccataa cgcatgactt cttctaaagt agacggaacg atttcatttt caatcactaa
    20881 ctcatgagag attttattga accatctcgc ttcttgatca gcatattctg aaaaaagggt
    20941 acttaattct tgcgaagatg tacccaaaac atacaattgt gcttggatca atttcatttc
    21001 ttctaattta aaatttgcta atacatgccc caccatggcg ccagcagttg gtttatgatg
    21061 gtcgatatct gcttgttttg tttcttgaac aaatttttct tccactatat tcattgattt
    21121 acgcctcttt tacttttgct gattggactt cataacctaa tttttccaca actgcagcta
    21181 attgttcagg gtggacttca tctggatcaa agtttgcttt gattttgctc gcattaaaca
    21241 aaactttcgt attgcttacc ccaggctgtt gagaaaccgc atgttcgatt ttttgcatac
    21301 agcttggaca agctagtgta tctaattgca taataatttt tttcatcgta gttcttcctt
    21361 cctttttctt gatagtctta ttctagatta cagcttccat aaaaaaattg attcttatca
    21421 agttttacga tttttcttct ttgctttcgt gtccaaaata caataaacgc atcgcgttaa
    21481 agataacgat caagatacta gcttcgtgaa cgaacatccc actagccatg taaataaacc
    21541 cggcaaataa gccgttgagt aaaaataaga cgacaccaat ggcaatcact acattttcac
    21601 gggtatttaa aacagttttc ttagccaagc ggtaggcatg aaccaacgat tcaaaattag
    21661 attgcatcaa gacaacgtca ctcgtttcga tagcaacatc cgttcctgat cccatagcaa
    21721 tcccgatatc agccgcagcc aaagagggag aatcattgat tccatctcca ataaaagcaa
    21781 cgcgcaatcc ttgttcttgg tattttttca caaattgaac cttttcgtct ggtaataatt
    21841 cagcatggac ttcatcaatg cctaacatat cagctacata atcagcagtc atctgattat
    21901 cacctgtcag catcactaac tgttttgctc ctgcttgttt caacttagct aattgttcag
    21961 cgacttctgg tcgaatcaca tctgacacac ctatgatttg agtgattttt ttgtcgattg
    22021 ctacaataat gaccgagctg cctgtttgtt gtaattgatg taaatcttgt acttgctttg
    22081 gtgtgagaga aagtttgtga gcggcaatca atttggtgtt gcccgcacaa actgtatgac
    22141 catcaatctc agctgtgatt ccttgtccct tgattgtctg attatctttg actgctaatt
    22201 gttgaaaatc aatgtctttc tcctgagcat aatggatcac ggcgcgcccc agaggatgat
    22261 cggataacgt ttctaatcga gccactaaag ctaagctgtc cccttcatcc tctgtatagt
    22321 tcttgatagt ggatacagca gtagttcctt tggtcaatgt accagtttta tcaaagacaa
    22381 aagtatcgat tttggaaaaa gtatccattg cttcaccgcc tttgactaag atgccccgtt
    22441 tcgctccatt accgattcct gctacattcg aaacaggcgc accaatgact aaagcgccag
    22501 gacaaccaag aaccaaaaca gtgattgcta aacgaaaatc acgactaatc agaccaacaa
    22561 ccaacgcaat aagtaaaacg gttggagtat aatactgaga aaatcgatca atgaattttt
    22621 ccgcatggga tttggtatct tgtgcttctt ctactaattc gataattttg gcaaaggtcg
    22681 tatcatctcc gaccttagtt gcttcaatcg tcacgtagcc atctgctaaa atcgttccag
    22741 agaagacttc atctccactg attttgacga cttgtcgtga ttcaccagtc actgcggctt
    22801 catccgcata ccctttcccg tcaatgactc gtccgtccac aggaatagct ccaccagttt
    22861 ttactaagac gatatcgcct tcttccacgt catcgatttc cacttcttca gtcgttccat
    22921 cttcttggac aacactagca gtagatgggg ccatctcggt caaagccttg attgactccc
    22981 gcgttttggt caatgttttt tgttccagat agctaccaaa caaaaacaag aatgtaacga
    23041 tagctgactc cttgtattct ccgatcataa aggcaccaag cacagcaata gtaacgagta
    23101 aatcaattga gataactttg actttcactg cctgatacgc atggatcata ataggtatga
    23161 ccgcaataat agaagctatg gctagagcaa tgttatagaa caagacaaaa ccagtaaatt
    23221 ttccgataaa accaaaaata atcaacacag ctgataaggc ggtgatatga tttcgatgct
    23281 cttggatcca cttttgtaat ttcatctttc tccctctttt cctttcattc ttacgagact
    23341 aagtatagat acttatccat cataaaaaat tgaccactat caagtttagt caaaaaggcg
    23401 gttttctttt ggtagaatac actacaaaaa atagttagca agaagactca ctaaaagtga
    23461 tcttgccaac tattgtcgtt tctatcgaaa ttttcattga atgattttcc tgtacagcat
    23521 acatcggaga tctatttctt tatctaagat ttttatcttg ctaatttttt cctttagtct
    23581 ttcaaatcca cgtcgttcat agaattgata cgtacagcca ctatctgtaa aaaggaatat
    23641 ttcttttcct ttctctcttt tttcaaattc tgttagcaac ttggtaccga tgccttttgt
    23701 tttcaaatca ggatttgcag ctaaaaaaat gatctctcca tctggcgaat gcttctttaa
    23761 atatgctgca agcatttgtt catttgctgt ctcgtaagct cctttacttt ctttagcaaa
    23821 tatattttgt aaaaaatcga atatcttaac atatatttgc tgtccaaaag aacgatgttt
    23881 ctttttttct ccttttatct ccgccagcaa aacacctgcc aactcgtcct ctgcatacaa
    23941 agcaagaatt tgagttgctc gattcaactc catatacaaa aaatatcttc cgtaaagatt
    24001 cagcagaagt tcattttcca tatatctctc aaagttcatt ccttcaacag caaaatagat
    24061 agcttttttg taatctttct tttctaaggg tttaaaagtt agtttcatca tttcgcctcc
    24121 tcaacttcaa tgattgtgtt atacttacat tataatagac acagtgtcta ctatctataa
    24181 tcaatcatct ataagtttgt cgattaagcg acagctttgc tttgatatgt cggataagga
    24241 gataggtaaa tgaaaaagac agatagacgc gtcaaaaaaa cagaaaaagc tttggctgaa
    24301 acactatcca cattattagt aaataaaaag attcaagcaa tcactatacg cgaactaaca
    24361 gaaacggcag atgtacatcg ttcgactttt tatacacatt ataaggatat ctatgatcta
    24421 tatgatcaat tagaaagcaa cttttttcgg gatctaaatg aaattctctc ttatgatcca
    24481 gcccatagct atgaggaact atacactcgc ttgattgact atgtttacgc aaatactttt
    24541 ttatatcgct tatttatcct caaccatggt gatatttcgt ttcagaagaa agttaaacaa
    24601 gttattgaag aaaactatct gaacatatgg ctatatgaag acaagaaaac gattatcaca
    24661 gaagaaatga gattctttac tacgtaccac gtccaaggtt gtctatccgt tctcaatcgg
    24721 tgggtagaaa gcaattacaa gtactccaaa aaagaattat tagaactctt acagaaactg
    24781 aatgatcaca tagagaaaat catgccttga ataaaaacat actaagctta gttaagaaga
    24841 accgtaacct tctcgtataa caactgaatc ttatttagcc aaattgttta ctgaagattt
    24901 tttgagtaaa atttctataa ttcctactta ttgaaaagta gtttgtagtg ctgcttctcc
    24961 ctctctaagt gatatatctt gttgtaccaa tcaaattcac ctcatcatta ataaattact
    25021 tttaggctaa tttattacaa cttataggtt gaagctgtaa ccaatttata gtcatattat
    25081 atttttatca tccagtttat tgaattcttc tcgtttacct caattcattt tcaaggggaa
    25141 tcagctcatc atctaacatt ttacgccatg ctcgcttcat ttcttgtggg tatttaaatg
    25201 gtttcgcttc tggatgtttg gctttatatc cttcgtaatc cttactgttg ataattgctt
    25261 tcatattagg aattggatct tcacctggca tatattgcag attagaagca tgtaattttt
    25321 tctcagaaac aaaccactca ttggaaaaga catgaatcaa atcatcactt acttgtgtaa
    25381 aatagcgacg tttaatgaca aagatatctt cattgctatc tagtgtacct tcatttcttt
    25441 gtgcttaaat tcaaagataa ttttctcaat aaagattttt gattccagta agattccttt
    25501 actcctttta caacatagcg ttgtcctttg ttttgaaaca tcttcttccc ctctttgcca
    25561 ttaaaaatag cccaattctc tataaagaag attaagcttc attattataa tataaagttt
    25621 aaatttggtt tattacttac tttttcttat tctctagtaa gctaatattg aaaaaaatgt
    25681 aatcagatca ttatttttat atgttgtaac ttcctgataa gaaaactaat taaaagaaag
    25741 aggtaactac ataaactaat taaaaaagct aacttcatag ttggaggata aatggaagaa
    25801 acttcaatga ttgtttctcc ttgtgttcct tcaatcgaca ctagtcctat tatcaatctc
    25861 tcttttttgt ccatttactt ttgcgactgt tccccaataa tcaaatacag gaagcgttat
    25921 tttttgtcct ttagattcat gtactgtata gactattttc gaatccatca cttgataagg
    25981 catagtatgc cattccttgc caattcttac ttcatgattc tgcaaatgtt ctttgtattg
    26041 taatgcttcc gtgggtgcat agtcataaag tcctccggga aggagtgtcg tgtaacgaat
    26101 aagattttct tgattcatta ccaagtgatc tctctgagtg acaactttat gttcatagtt
    26161 tgcttttgtt gcagcagata cagccaacag taataaaaca attgccgtta tattaactac
    26221 ttttctttgc ttagctgatg tgctcttcat gaaaacgaac gataaaatca acgagccaaa
    26281 cagtacttga aagcctaaga ttcgccaagg aaattgaatc atttgaatgg gtgtattttg
    26341 taataaagac catggaaaaa atttggtgga taagagccaa gagactaccg cactaaggta
    26401 aatcactttt tctttgcgat taaatccttt aaaaaagaag agtggacaga tcaaagaaat
    26461 aataccaatg attcctaccg taaaggttgt caggtcatta ttcatcgcac caatcaaact
    26521 atccgagaca tttaatgctt ggtgttgtaa ggtcgtttta tctggctcat taatcgattg
    26581 aaccatgatt tgtcggaaca tcggatacca aaagtatgct gttaaaagaa tcgtcattcc
    26641 tactgccttt gacaactcca caatcaaccg gatgctttct ttttttcttg tttcacttac
    26701 tacaaagccg cctaagacta gtaagccaac ggctattaca ctcataaaag tggaaagaac
    26761 atgtgtataa atgagtaagc tcatactgac tgctaatgga attgcacatg gctttttctc
    26821 ataaatcagt gcgtaagcat aatacataac tatcggtata accgtaagtg caatcgcttc
    26881 agcaatagca gaacgatgat aaatatcaat cgtacggtac ccataaaatg tatataaaca
    26941 gctaaatata aaagccgcat cgattctttt taaaaatttt agtccataat gaaacatcag
    27001 catgatagta caaacattca atagccaaac atataagata taactaacga ttaaattatt
    27061 acttatccaa taaaaaatga ctgccggaaa aaaggtcaag tagggataaa aataattcac
    27121 tccgctccca taatgattaa acgtcgtaaa attgattgga ccagaaaaaa ttgaagataa
    27181 ccctttgact ctagcaaaat ggaaggcaat atcccccgat gtagaaatag tatgaacatt
    27241 tctaaaataa ttgattgaat aaagtccagc aataattgct aggagaatgg acaatattat
    27301 ttttttcttt acttgcatta cttaattata tactcctttc atggattgct ttatctagta
    27361 taacttaaat tttaaataaa tcgttattta tttttactct cacttaaaaa agcactaaaa
    27421 ttataagaga gggaggtaat ggtctgaaca ccaagaattg ttccaacatc gaattgctta
    27481 actaatgagt tcaaagctta attatgtggc tcttatattt accgagcgtg gattgcgatc
    27541 tctttagcga aacaaacatc tttcataaaa aaaacagcca tatccgcttt cttggatatg
    27601 actatttact actactttac tatctttcat tcttcttgtc tcacttatga taaggcgctg
    27661 cgtatcatga gtgaatgata ttaggaaaac ttcataaaat aaatctttta tacatttcca
    27721 cttctagatg gtcattcatg ttagaagaat caaactattt ttttactgtc gtaataatat
    27781 taaaacacta gaacaaatca attaaattcc ataaaatata aataatagac ctagcatcat
    27841 ctggtataaa atggatgcta ggtccgttat atttactcaa aattgattct acgaatagat
    27901 cttcttatca tttctatttt agtagtcatg cgttgttgtt cttctaaagg tggtaatggt
    27961 ataagtagtt tagataaatt tgtaccattt acatttggtt gcccagttcc gtaagaaatt
    28021 ttttctaata acttccaata taatggcgag tctaagaagc agtctacgta ttctgataat
    28081 aatttctcaa ctaacctaat tcgaatcaag taagaagcaa aaacagattc ctcacttatt
    28141 tccttaacca agaaactttt tcccatagtt cctcctgtcc ttgctatcaa aatgtcattt
    28201 tcttccaatc ttaaatcaac tagtttagaa ttactaatat cacagtaagg cacactggac
    28261 caatttacac gtccctcttg tatatctgtg attctcaaaa acttaacatt gccttgtttt
    28321 ttcgccgaat ctgtatagcc atattgaatc ttagtagaaa tacttcctaa ataaacccat
    28381 agtcgaacat cgctagatga tttttcttgt cgttctttat gaacaacagt gatcatcttg
    28441 agttgtccga ctatttttta gttgcagcaa tctttttggg acgcttattt gcatgaagca
    28501 acgttgctaa gtctagtaat aaaacattgg ctaacacagg attggctttc tcgcgatacg
    28561 ctgcggcgcc actttcaaac aatactgcta gacgatcttc tacaacaacg atttgttcca
    28621 aatacggtgg aaatttgatt cgttttagga tccggctagg agagtcccgc tcggacacta
    28681 agagttccga ggtataagga ccataagaac gactggctaa gagataatgg ccataaaaag
    28741 ccacaccttg aatcttatca gatgtttttc tgctcattgt cacggttggt tggattttgt
    28801 ctttgcggcg aattgctgtt ttcatttcag ctatcgtcgg caatagatag aaagtcaact
    28861 gtccttcacc ttttagtgtg aagttgccag ataccagttg atcattgttt tgagtcaaat
    28921 acgatgcttg tggaatctct gagagatcag ttgtcagcca ataagcgatt ggctgtcccg
    28981 tctcttcaga tgtatctgct aagatatcga tcaaacgtaa agcggctact cgtccagtag
    29041 cagatcctgt gattgtcaac cataaaagtt cccgttttgt atcatatact aagcccccta
    29101 catgtggccg tttaggtaaa atcagcagtt tgatcggctg tcctgtttct ctatccagta
    29161 catgaataat agaatgatgc tgatggtcat agcagtaggc agaaataaac acaaaatctt
    29221 gagaaaaagc caacccttgc ggcgtcatcc attgacaaac ctcattttcg ccggtttccg
    29281 gcaccaccat tcttgtttct gttaatccag gaatgttata ttgttttgct tcagcctttt
    29341 cccaagctgc ttgaacaata ggataccgtt ttaacttttt ttcaatatcc tgatgtatcc
    29401 gttgctgctt ccaatgctta aactttagga catagtaaac aagaaggcca atgaccagca
    29461 acactaaaat cattattgct acccgctgtg tcattttttt gcctccttgt tctattcgat
    29521 caatcgtcca tataccgcta ttaattaccg taactacatg tttcttttac tagcgtttct
    29581 ttataggatc tttcataatc tcatttatag taacattaag aatcccttat tctactatag
    29641 tcacttccac atcaatattg cctcttgttg ctttagagta tgggcaaaat gcgtgggctt
    29701 cttctgcgat tttctctgct tggtccttct caagtcctgg caaagaaact tctaaaacga
    29761 ccccgatttg gtagccccca tcttctaatt gaaataaaga tacccgtgct ttgacttcag
    29821 aatcagactc aagattattt tcttccagca tgtgttgaac cgcgccgttg aagcaagatg
    29881 cgtatccagc cgcaaaaagt tgttccggat ttgtcccttc actatggatt cctgggcggt
    29941 cgatcttcat gtgcatactt ccgtttggtg cctcaacttc gccatcacgg cctccacgat
    30001 tgatcattgc tgtttcgtac atttttttca ttgagatcat cctttctttc gtcgttctat
    30061 attaagtgta acgagtattt tttaatctga caaaggtaat gcttgcattc ggcgacatca
    30121 gttagacaac atcgatgatc agtgatagaa gcagtttatc tatacaaaaa aagaagggtt
    30181 ctatgatatt tggtgtcctt actcgccttg agtaacaaca ccaaatatca tagaaccact
    30241 taatcagctt cacactgctt tttctacttt cgtagttgaa aaaaacttaa acaaatcatc
    30301 ggcaaatagt taaagaaaaa acttaatcgt tgaaagaagc ccaattgctt aaagaaggca
    30361 aactgactaa tcgacggaat ccgtgctaat ccgtaaagac ctgcaattag taaactaata
    30421 actgttaaaa caagataaaa atggctaagc gtaccttgac cactttgacg ataaagcaga
    30481 acaagtaaca atgggaaaag tagaaagcct gcatagccta gcccagaacc tatattatgg
    30541 atccaagtcg atagattaca agagctttca ttcgtattga tactgaataa gccagtaaaa
    30601 atacaatcac ctatcccata taaaccaact gttgcaacaa caagtattgc aagtgttttt
    30661 gatgttccaa caaataggtg atacaacgca ggcaacgaaa gaacaaaaaa aagtccagat
    30721 acaactgacc agaccaagaa agcacgtctg actggactat ctacgtcacc aaacacacta
    30781 attacggtag tcatttgatt cagtttggga taaaaaaggc caaggatata cggtgtcgat
    30841 aaatcactca tcacacctaa taataaaaaa taaaaaccat atttttgcaa aaaaatcatt
    30901 ttcttcccct actttttagt gattattcga tacatccaac aatcaaattt tttctcattt
    30961 taacacatat ttttattcta gttgtctttt gaacaatcaa taacataaag gtgagtttct
    31021 tctacatttt aaaaaatcga atggcactga agagttcagt tgtcagcatc aatctcctac
    31081 tcaaaaaggc aaaaaaacgt aagtcagatg ttgttgacat ctcacttacg catccattga
    31141 ttgaaaattt cttagtaaaa tctactagcc taaaaatttg aagacttctt ctcgatcata
    31201 cagtttaaat actttctcgc ataaaaattg agtaattagt gccgcaaaaa cagggatgac
    31261 taaccaacaa agaacaacaa gaaagccatt tagccctgca tctaaagaag ccaacggacc
    31321 aacaagtccg accacgccga aaccagcaga agcaggcgta cctgaaatag aaaatagagc
    31381 gacaggaata gctgtaatca ctgcactaac taaacaagga ataagaatca caggttttct
    31441 aaatagatta ggcatcatca tcttcatagc gcctaaagca atcgcaattg tcacacctga
    31501 cttattaacc ttccaagagt tcactactaa aacaaaagtg gttgcagcta cgcccatcgc
    31561 agccgcacca gcagaaacac catctagttg gattgccatt ccgattgcta ctgttgaaat
    31621 aggagagata atcaaaaagg caaaggaaca accaatcaag atagacatta acagcggttg
    31681 taaggtagtg aagttattaa tcaatgatcc aattgcagaa gtaattgctg ttacaaaagg
    31741 gaataaataa aaaccaagta aacctgcacc tacacctaca acaatcggtg ttaacacaat
    31801 cgacactgac ccaaaactat ttccaatcag taaaatcagc ccgacagcaa tcgatgctgt
    31861 cagcatcgta ttaataatat cgcctgtacc agcaccaacg taaacacccg tttcacccaa
    31921 atcaggtgtg aatttgacta caccagaacc aacaaaagaa gctccggcta caaccatcat
    31981 tctcatcgga tcaaatccaa attgtaaggc aatcaaacca ccaatgatca aaggtgttgc
    32041 tagttgaaaa ataactgcta actgtgcgat cgttaccgca aagggatacg cactaaaata
    32101 ttttaaaatg gcacctaata ctgcattagg aatcaatcca ataatgattc ctgttgctgt
    32161 accagcgagg actttattca gaaaaatttt cggtgatatt ttttgtgaag tttccattca
    32221 atctctcctt tattttacgt tcaaactatc ttcttttgca tggacaagct cagtcaagaa
    32281 atcacaataa ggcgtcgcaa caccatattt cttccctttt ctagaaattg cgccattgat
    32341 ataatcgatt tctgttaatc gatggttctt aatcaagtct tgatacattg aaggataatg
    32401 taacccaatt gtttccgggt caaaacaaga ttcacaatgt gcaatgactt ctgggacatc
    32461 tagttcaatc ttctctactg ctgctacttt ggcaaactca ttgacaatcg tcgccaccat
    32521 tttatgagca gtcgatgttt ttcctagctc agccatatta acgtctaaga ttgtgcatag
    32581 tccgttcatt gttccgttca cacatgcttt gcgataaata gaatagtgaa tattgtcaga
    32641 aaaatgagca tttaatcctg attcagacaa tttgtctgct aatttttttg cagctgcttc
    32701 ttttccatca cctaaatttt gtaattctac tgaaccactt ccaaataatt tgacctgacc
    32761 aggaccttca agacctgccg tccacatggt atttccaata tagatatttt ccattggtac
    32821 aaatttctca ataatatctt catgcccgat accatttaat agacataaga cctctgtatc
    32881 ttttttgatt aatgattgga tatcctgcag cattttttcc agctgcatcg ctttggtaaa
    32941 tagaataatc agatcaactt gatcttcttt ttctacttcg gattgaagaa cgattggtag
    33001 ttttgcttct acctctttac cattaaaatt tgcttgtaat ccatgttctt tgatttgttg
    33061 gacatgttct gcccagccat cgattaataa tacttcgttc ccactttggt gaagcatcaa
    33121 cccaaagcga cttcccattg cgccagcgcc tgcaattgct attttcattg attcttcctc
    33181 ctttttcttt ctattatact catttgagaa tcttttcaca acctcgtttt gttattcttc
    33241 tcttatttat catgtttata tccaccattc aagttatttt atcagcaaat caataaaaac
    33301 tggaatagaa tcccaatttc atcgtaagag aaactagact agcaataaga aaatagaaac
    33361 attcatagaa aaaatctcac tcctctgatt ataaaagagg gggcattaac ctcgtgtata
    33421 ctaaaacctt ccattcattc gatggatgat tttctttttg tgaaaaaata ttcattgtag
    33481 tacgatgttg cgcaacacag acggatggta ttgcttatta tttattaaaa tcgaacaata
    33541 cacttattta aaaacttctt tcccagattt tcttccattt ttacagttat aactagtatt
    33601 atcatgaaaa atagcctttt attgtctatg ggaataataa tttaaaattg gtactttttt
    33661 attaattagt tcatcgccca ataatctctc cagtttctta gcatctcctg actcaaccgg
    33721 aattatccaa gcccagtcta aataattttt taaaatctca tcatattttg caaatatttc
    33781 attgccatat tccgtcctta aaattatatt ttcagtgcca gacaagtgat ttatattgag
    33841 ttgataaaaa agatctccat ctaaaaaaat atcattagaa gaagatttcc ccacagtaat
    33901 gaccattcca tcagctctat gtgttacata caaataattg tatgacctca tttcacctaa
    33961 tgaatcaatt atttcttgcc ctttagctct aatatattga tctctattac ctatctcact
    34021 cttatttaac aaaagttttt tcatgtcaaa tttaatcggc tgttttattt ttgtaaattc
    34081 gcttctacta ctaatccaat ccgagattaa tttttcaaca tgtcccagag taaactctga
    34141 tttattcgct aaatactttt tttgttgtat taaagacatc tttccccgaa gctcaaaatt
    34201 gagcctacat cgattctcta tctcttcaaa aagcatctta tcttcatcat tcttatattc
    34261 atcattcata aaaccaatcc agctcctcga ttaagataat attttaatct catacaaaaa
    34321 ctagctctca tcaaaacaac cattgttttg atttctcatg aaatttcttt atacttttct
    34381 ccgattataa attcctaacc ccttgagaaa attacgcata tatttatctc cgcaaggctt
    34441 aaaatttcgt tggccttctt ttctcaaaaa tgccccgatt tcgccttttg atggatagat
    34501 ttctgcctca gcaaaaacgt ctaaaatatc atcagtggtc atagacaagg cgatttttaa
    34561 tttttttagc aacacattgt tgatatattt gatttccttg cttttttgcg gcgtgtctac
    34621 tatcggctta tctttttgcg gaccacgcgc caagagaatc aggccattta ggaatgcgtc
    34681 aaaaacttgg ttgttgatgg ttttttcata cacattattt tctgcattat ctttgttctt
    34741 atcctgtact ttggtcagta ccgcctgagc ttcttcttta gtcagtggta caccgcctag
    34801 ctcaaaagct ttaatcaaat ccgtatcttt caaatcaatc gcataacgca atcgcaataa
    34861 cctatcattg ttattcattt gttcctccga agtatttagt ctttactttc ttacgtactt
    34921 tttgtcttgc taagattttt aggatcaatg ataaaaaccg catcacttat gataaggcgc
    34981 tgggtatcat gagtgaatga tattgctgaa tacaaatagt ccgaccacat taagttgatc
    35041 ggacttcata agcattttat tgactaatac ttttttgctt aagaattgat tctaacatct
    35101 tttgctaaag ttaagcatcc tatagttcct gcattatctg ctaacttagg tgtgacaatg
    35161 tattcttcga tatttggcgt atcgacatag ccgttaatta gttctaaaaa acgtctttgt
    35221 actttctttt tcagatgttc ttgttgcatg acaccaccac caaaaattat aatatctggt
    35281 gaaagcatca gggtcgtatt acaggcacat tgtgcaatat aatccgcctc gatttcccag
    35341 aacggatctt ctatagaaag atcttgtccc ttggttcccg tacgcatctc gatagcgggt
    35401 ccagatgcca acccttcgag acaatcatga tgaaaaggac aagtaccaga gaaagtatct
    35461 cctgaatgtc tcttaactaa cgtatgcccc atttctggat ggctaaaccc ttcaacaaaa
    35521 atcccatctt gtatagctcc tccaccaatt ccagttccaa cagtgtaata aacaacactg
    35581 gataaacctt ttccatgacc tgaaacatac tccccgtaac aagcagcatt cacatcggtt
    35641 gtccaggcaa ttggaatttc gaaatgctta ttcaacgttc caacaaaatc aaaatttttc
    35701 caggcagttt ttggagtaga ggtgatatgt ccataggtct ttgattcacg atggatatca
    35761 atcggtccaa atgaccctac tccaatgctt tctaattgtt ctttatagtg attaaagaaa
    35821 tcaattacca aactcattgt ttcattcggt gtagttgtag gaaaactcac tctttctaaa
    35881 acctttaaat catcattgcc aatggcacaa acaaatttag tcccacctgc ttctattgag
    35941 ccatacattt cttactccac cgtcctttta tctaggaatt cgttcttccc tgtctaatag
    36001 tttttcgaaa aactcatgtg gttccttttg gtaccaatag gcaacagaag aaatatcgtc
    36061 ttgacgctca taaagcttga tgtcatcatt tcctagggtt tggaaagtaa cacgtaaatt
    36121 ttctttgaaa ctaatggggt cgggtaaatg ccagcggtac aacccatgca tcggtaaagc
    36181 atcatcgcca aaaccatgaa ctggatttgg attaggtttt ccagcactaa aataatcccg
    36241 ggtgtgatct cttttagatt gaaaaggata gcccataaat agcgtattaa aattttgagc
    36301 atatgccctt tctccaaagt tctttttatg gaaagcccaa gcgccgccaa aataatcttc
    36361 tgctcctgta gatgttattg tagggaaatc ttcatctcca tctatataaa acttaaattc
    36421 tccttccccc caccagtatc tttccaatgc gcacaaagca aagtaggttc ctacataata
    36481 cccagtgcct ttgattccat caataagggt gtaatctttt ccttttgtcg tgatgggttc
    36541 acggttccat ttagcatgaa aatacatcgc atcatccggt acttcagtca atgcataatt
    36601 aaatgtataa aaaatgtgct taataaactc aggatgttca ttcgttaaag taatcttagc
    36661 tttttttcga aatggcatct caaaatagca attcatccct gatgttggat tcactacgat
    36721 tggtaaggaa ttcacttcgc atcttgtccc aaacccatta caaaaaaaat ctcctaatgg
    36781 actttctaca gaaggagtgg attcatcatc ccaataaata cgcaaaatta aatcacgtaa
    36841 gacgaaactc ccagcgattg ttttgtctgt cactgtcatc caaaaatgac gtaaaattcc
    36901 agggccttcc atttctgcta aagtaattgt ctctccagca tttatcggaa cagaaggtga
    36961 cccttttctc ccaattccta gatgactcgc tgtcattgcc gctttccctt tttcaccatt
    37021 tttattttct ggtgaaatag ttctactttc ctctcccttg tggagccata tattatttaa
    37081 acaattcatt ttattcgtcc tctatccttt cttcactttt ttgattattc atatagatga
    37141 tttgttgttg tgcctccgca ataattgctc caatatctaa attatcattt cctaactgca
    37201 aagcgattga cattgccaag ggaagattca ttcctgcaat tacgtgcact ctgtcagaaa
    37261 tataggtaaa aaacttttga tttacacttc ctccagccat gtcagttaaa acaattattt
    37321 cgtctgtagt atccactaac tctttaattt gttcatctat atcatcaatt tcttcgacat
    37381 atgcacataa gctactaatt tgattatgca tacctgttaa aaactctagt gtctctttaa
    37441 aaccctcagc tagtattgaa tggctagcaa tgatcaatct tctcataatt caaatccttt
    37501 tcctttacgc taatattcca aatgcagcca taaccatcgc aaaaacaata acgagtagaa
    37561 tcaaaatggt catactgatt tttttcttac tgagtagata atatgctgca gcagtaataa
    37621 ttactggaat taatgttggt aaaattttgt ccaacattgg ttggattttc atactaactt
    37681 caccaaaagt gaatttaagt ggcgttgaaa cactgataac tgaagcaatt aatgatccaa
    37741 ctactgttag ccccaatact gaagcagctt cagttaaata attaatcttt tcaccgtatt
    37801 cagtaacaat cttcattccc tgcttataac caaattcaaa gcctctcatt cggaaaaaga
    37861 agattaccat gattaaaatg aaccataaaa agattcctac aggattattt tctaaagcca
    37921 tataagccgc aattgatccc atgatggttg ggatcatcgt catcaaaaga gagtccccaa
    37981 taccagcaat tggacccatc gtaccaactt taaagtcatt aatcgcatct tttgcttcta
    38041 atccttgctt ttcctccatt gcaacacaag cacctaaaat aatggctgcc agccaaggct
    38101 gtgtattgta atactgaaag tgattattta aagcttcgat gtattcatca tcatctttgt
    38161 ataattttct taaaataggt gacaatgcgt aagtcacaga tgcaccttgc tgtgtttgat
    38221 aattaaaggt acaaactgac atcaaccaac gatagttcgc tttcctaaga tcctttttcg
    38281 ttacttgata tttttcgctc attttattca tcctccccaa taaacccaac atcagaagct
    38341 cccgcagaag cagtgatttg tgcatctttt tcagctctat gatacacatt aaatgctaaa
    38401 gcgaatccta tgatcgccgc tccaataata ggtaccttca aaaaagcggc taagaaaaat
    38461 ccaacaagta aataactaat gtatcgacct gtaggcataa agcgtaacaa catcgcaata
    38521 ccaacagcag gcaacatttt tccggctaat gttagcccat ccataaacca attaggtaaa
    38581 acatccaaaa cgtaattaac agcagactgt cctaaagtaa cggcaataaa tactggaatt
    38641 gctgcagata aaccaaagaa aattggcccc aaccacaaaa cactattcat tttcttaaat
    38701 tctcgtttat tcgcatattc ctgtgatttg cgaacaacaa aaccatttaa gattttgaca
    38761 attacatcta gttgcacccc taacatacct acaggtagtc ctattgctaa tccggcttct
    38821 actccaagct ggctaccaaa tgccgttgca ataattgcgc acgttccata gtccggtaca
    38881 gatgagccac caaaaccggc aactcctaat gacatcaatt gaactgtacc gccaactatc
    38941 aaacctgttt ttatatcacc catcaaaatt cctgtgaata atccccaaaa aactgcgtaa
    39001 tttacaaaga tcatcggaat cccataataa tcaacatgtt taataaatgc taatatagtc
    39061 agcataataa tttgaaaaat agtaaaatgc attatcctta ctcctttatc ctaattttga
    39121 ttgaatttcc tgtgccttat ccgccggaac aaattgtgta acaatttcta caccagaatc
    39181 caacaatttt ttatacgtgc tgatattttc atctgatgca taggctctag aagatagctg
    39241 taatgcatta tctttaacaa cagtaccgcc aacaattagt cggtcaattc taataccgtt
    39301 atctactaaa tgaaggattg tttccggctc tttcacgatg acaaatactt tttcctgatc
    39361 gtatttcccc tttttaaaat tcgcaatcgc tgtttcttca gtgataattg atacagccat
    39421 tccagcaggt ctagctaaac gcatacttga tttttggatg tcgttatttg cgacagaatc
    39481 atcgatcacc atcactctgt ttgctttaga cattggtgcc cattgcgtga caataatccc
    39541 atgcaataaa cggttatcaa ctctcgacat aacaatactc ataaatactt cctcctttat
    39601 ctttcatttt cttacaagca attaccatgc caaaacaaaa agaacttgat aaatcaagct
    39661 ctttttacat aatcataaac gtatttaacc tcatgaatcg ggatgtcgac actataataa
    39721 tgttcaacga cactgaaaga ttgcttaaaa tgtgtctgaa atttttgaaa ttcctcactc
    39781 gtttcattga aataaatttc atcttccaaa gtattttgtt ttactaatcg ttcaattaag
    39841 caactaatgt gaacatataa tccgaaacac gtattattat caaatgaaat tcctagatca
    39901 ttttgtaaga tgtatatagc atctgaaacc cgttctaata atttagtcgg atttaatatg
    39961 gtcaattgct ccattaaatt cgttagacta aaattcttca gaatattatt gttcaaaact
    40021 ttcagttcat tatcattaaa gtgtctattc aattgattgg agaatttact tatattcatt
    40081 cctaaaatca tatcttcaat tgaaaagaat tctacatctt ctagatgtgg atttagtgtt
    40141 ccaacaataa aaagaatatt gttctcttta cgaagctccg ataaatagtt ttcattcact
    40201 aaagagtaat agtcacacgt ttctatgaca agatcagtat cccttggaaa gctatcttca
    40261 agtatccttt ttaatttaaa cgaagttcct aatccgcttg cacaagaaca gacaatcata
    40321 tccttcttaa tatttgatga ttcataaata taatccacat tttgattttc ttttacttgt
    40381 tcaagaatct gtttaagcgg taaatctaat aatatctgat ttgcaacatc aatagccatt
    40441 cttgttgaaa cattgtttag tagtccgaat tttttttgag cgtctagttc caaatttaga
    40501 taaattttct ccagtgaacc catatcaaca agtaaaataa tttcttcata tccggtacac
    40561 tcttgtaagt atctattaat tttgtctgca atctcactac ttgaagtcat tagtggcata
    40621 tcaatggcgt cgtatatata tctctcaacg atcctattag cagtacttgc tatacaggtt
    40681 gccgttagat ctccatgagc caaaatcagt gctaaacgtt tttgctgaaa ttctttacta
    40741 cacattaact taaataaaat aaccaaaaca tttttttgaa tttttgttaa ataaatatcc
    40801 cctatttgaa taaaacgatt gactaattga acttctcgac tacaccaact attaatatca
    40861 ttgatgaagg aatataattt atcgtccgat gttaattgga tttgataaat ccaagaattc
    40921 aaaaagatag acgttatttg aagataataa tagtcaaatt ctatttgaaa atctctctct
    40981 atttccttaa catactgtct aaatcgaatc tcttgatagg tgggatatgt taaagctgaa
    41041 ttattttgga tatcaacatt cttttgtcta aaatatctat catatttctc aaaaagctgc
    41101 tgcttatcag tgtctttctt ccacgtttga taaagatact ctataagttc gttgatatta
    41161 aaaacttcgt ctactttttc caaatcatcc atttgaatat attttaattc attctgtctt
    41221 ttcataacct tcatgccgtt gaaattcacc cattgtggta aatgatacat ctgaatataa
    41281 agttcttcca aatcatctaa gaaataaaag gcattggcac aggtcaattg aatgatattt
    41341 ttcaaattgc caacattttc actaaagcga tagtttaata aaaaatctaa taattgttga
    41401 gatatcagta ttttctttgc tagtctttct tcttctgatt taaaaaatat cttgattaac
    41461 tgttttcttt cataaagaga acgactgtct aatgttggaa gtgttagctt tacaggtatt
    41521 cttctcaaca aagttgataa tagtttatcc tcaggtggtt ctgatgttgc aaatataatc
    41581 cagcaacttg atgtgtacca gttttcatta tcacccatcc gatgaaattt cctcgtatcc
    41641 ataaactgaa aaagtttctc ctgacattca ttgctcaatg catgaatttc atctaaaaat
    41701 aagactccat tattagctaa ttctgctaaa ccctttcttc catcttcggc tcctgtatat
    41761 gcacctttta catgcccaaa aaaattggac aagaaaagtt ctggattatt ggcatattca
    41821 ctacaattaa ctgaaatgaa agatgccttc tcttctatat aattattggc caacaaatcc
    41881 ttatacacat aatttgctaa atagcttttt ccagttccag tctcgccatg aagtaaaatg
    41941 ggtaagccat ttggcggata gtagattgct gctttaattt gagcaattac atttcgcaga
    42001 cttccttgac ttccgataac cctttctatt ccaaccctaa aagagctatc ataccatttt
    42061 tccgcttcct ctgaagagct aaaaatttgt tgatttggaa ctttctccgg taaagaaaag
    42121 aagattactg gacgagtatt gatttttcca aattctccat cttttacgaa ttcattcaaa
    42181 tattgagaga caatattacg actaacattt aatttttcag atattttctg tgctgtattg
    42241 ttcccccatt tatttttaat ctcagagttc tctatgacat aattgacaat gcgttctttt
    42301 aattcttcca tcacagcacc tcctcgacac tattcgaatt ttgccgacag tatttttcca
    42361 taaatatgac ttgctaaaaa ggctttgttt agatcattca attggaacgt tgcttgtttt
    42421 gcttgatccg ctaagacgtt gaaaagatac tctggcgaaa tcgcataccc caaaatatca
    42481 acgattgttg caatcagatc ttcttttgat tcttcatctg aaagtaattc acgatacaac
    42541 atcgtttgtt tgcttactgt gtcatattcc tctaaggatt catctgctaa aagaaccact
    42601 tgttccaaca aacggtcgga taaatattta tagaaaatca gccccaataa ataattttta
    42661 tattctgacg catccatttt actacggaga ttatctgccg cactaaataa cttctgattt
    42721 aattctgcac ccaaaaagat acactcctat ctcttattta aagttgctat ataccctctt
    42781 attttagcat actcagtttt agaaaaagca aaaaaataaa gaaacttatt cttgataaca
    42841 agctacgtga cgtatatccc taacacaaaa atagccatat cctttggttt ggatacggct
    42901 atttgatatt actcattcaa ttatcaaatc acagtaggtg tgaatctcat cgggatcggc
    42961 aatatctact tctgattagg atcaaaggtg attttctcaa taaaggtgtg atacaaagct
    43021 ttaacttgct tcttctcact ctggataaga aagcaatcca aactagtcaa tatctgttgg
    43081 acatctttga cttgaatcgg ttccccttgt tgttgaaaga tccctaagat ttcattctct
    43141 cgaatttgta actgtcttcg tttttcagtc aattcattta aacgatcttt taacatcgga
    43201 aacaattcgg gactatcttc caaagcagct tcctgttttt gctctaatag ttagattttg
    43261 cgtaccattt tcttctttta ttttccttcg attgctgatt ttaatatagt ctaaaggaaa
    43321 tttatattta ttgtattctt tataacttca agagaacttc gtttgagtat tactgtattt
    43381 ttttaattcc ataagaaaat tagttattac ctgccaccta atcagcaaat ctgaacctga
    43441 gtcaatataa ttaatattat tttccatctc caacattgta agtactgttg gtgttaatat
    43501 agggactttg tacaattgta tttttttgat tttatcatct gcacaaagga gattttttaa
    43561 atctaatcct tcttttattt caaaagttga attttttaaa tctataagag taaaaccaat
    43621 tccttcatac tgaatttctg aaaatcgaat ttttctccca gttgatagat caaggggcag
    43681 aaaacctttt attacattgt gagtgtcacc atcatttaca atgtcattag gaattttgat
    43741 tttagaattc tgtggagcac ctattggaag ataataattc attataattt tgtagtcttc
    43801 atgaggaaat aaagtacttt taggattgct aagatattct cgtaccgaat ctaagaatgg
    43861 cttatccatt gaatcttcat ccccatttaa actaaaaaac attcctacaa ttgcttttgc
    43921 aactctaagt gaattcattt tctttattga atgtgttaaa tcagacttac cattctttaa
    43981 acttgtattg ttataaagga aatttttatt gtcttctgca aatctaatat attcctcaac
    44041 atactcacta ccaaaaaaac tattacattt actacataac g
//
LOCUS       DAFELK010000018        42453 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFELK010000018
VERSION     DAFELK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.019"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            214..498
                     /locus_tag="LP433_001215"
     CDS             214..498
                     /locus_tag="LP433_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBL2005391.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="LP433_001216"
     CDS             complement(779..1198)
                     /locus_tag="LP433_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBL2005392.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="LP433_001217"
     CDS             complement(1200..1784)
                     /locus_tag="LP433_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBL2005393.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="LP433_001218"
     CDS             complement(1831..3306)
                     /locus_tag="LP433_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBL2005394.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="LP433_001219"
     CDS             3487..3798
                     /locus_tag="LP433_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005395.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="LP433_001220"
     CDS             complement(3913..6249)
                     /locus_tag="LP433_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2005396.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="LP433_001221"
     CDS             6391..7059
                     /locus_tag="LP433_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2005397.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="LP433_001222"
     CDS             7062..8105
                     /locus_tag="LP433_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2005398.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="LP433_001223"
     CDS             complement(8342..9223)
                     /locus_tag="LP433_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2005399.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="LP433_001224"
     CDS             9382..10110
                     /locus_tag="LP433_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBL2005400.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="LP433_001225"
     CDS             10266..10583
                     /locus_tag="LP433_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2005401.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="LP433_001226"
     CDS             10576..11184
                     /locus_tag="LP433_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBL2005402.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="LP433_001227"
     CDS             11239..12030
                     /locus_tag="LP433_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBL2005403.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="LP433_001228"
     CDS             12168..12656
                     /locus_tag="LP433_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBL2005404.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="LP433_001229"
     CDS             12707..13579
                     /locus_tag="LP433_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL2005405.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="LP433_001230"
     CDS             13755..14117
                     /locus_tag="LP433_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2005406.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="LP433_001231"
     CDS             14126..14878
                     /locus_tag="LP433_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005407.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="LP433_001232"
     CDS             14892..16694
                     /locus_tag="LP433_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2005408.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="LP433_001233"
     CDS             16971..18011
                     /locus_tag="LP433_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL2005409.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="LP433_001234"
     CDS             complement(18063..20207)
                     /locus_tag="LP433_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL2005410.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="LP433_001235"
     CDS             complement(20564..21937)
                     /locus_tag="LP433_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2005411.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKNIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LP433_001236"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LP433_001236"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBL2005412.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LP433_001237"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LP433_001237"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBL2005413.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="LP433_001238"
     CDS             complement(23385..24398)
                     /locus_tag="LP433_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL2005414.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="LP433_001239"
     CDS             complement(24479..25078)
                     /locus_tag="LP433_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2005415.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="LP433_001240"
     CDS             25264..25965
                     /locus_tag="LP433_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005416.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="LP433_001241"
     CDS             25975..28686
                     /locus_tag="LP433_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2005417.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="LP433_001242"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="LP433_001242"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBL2005418.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="LP433_001243"
     CDS             complement(30825..32006)
                     /locus_tag="LP433_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2005419.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="LP433_001244"
     CDS             32258..33781
                     /locus_tag="LP433_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL2005420.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34579)
                     /locus_tag="LP433_001245"
                     /pseudo
     CDS             complement(33850..34579)
                     /locus_tag="LP433_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(34592..35872)
                     /locus_tag="LP433_001246"
     CDS             complement(34592..35872)
                     /locus_tag="LP433_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL2005421.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36013..36615)
                     /locus_tag="LP433_001247"
     CDS             complement(36013..36615)
                     /locus_tag="LP433_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL2005422.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36860..37066
                     /locus_tag="LP433_001248"
     CDS             36860..37066
                     /locus_tag="LP433_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005423.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37378..38097
                     /locus_tag="LP433_001249"
     CDS             37378..38097
                     /locus_tag="LP433_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL2005424.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38178..38861)
                     /locus_tag="LP433_001250"
     CDS             complement(38178..38861)
                     /locus_tag="LP433_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBL2005425.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39079..41265
                     /locus_tag="LP433_001251"
     CDS             39079..41265
                     /locus_tag="LP433_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL2005426.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            41611..42021
                     /gene="spx"
                     /locus_tag="LP433_001252"
     CDS             41611..42021
                     /gene="spx"
                     /locus_tag="LP433_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL2005427.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            42035..42391
                     /locus_tag="LP433_001253"
     CDS             42035..42391
                     /locus_tag="LP433_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBL2005428.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        13805 a         7495 c         8504 g        12649 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat attttttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataaa ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt tattaatcga ccgcacattt tgtgtattga
    33961 taacatagga tttatgacaa cggataaaat tccgatgcat tttctcgatt tctttgatct
    34021 tctcatagaa ttgtaattgg gcatgagtca aatggacttc cagtttatgt ggcgctccta
    34081 gcgaagtaga aaaatattgg atgtctttga tcggtaaaaa tttgatctca tcattaaact
    34141 ctattttgaa gatatctttt tggatttggg acatttgaaa atcttcgaaa attttgctca
    34201 ggatatgctc gacattttct tttaaatcat aaagatcttc tttgacgata taatcagtcg
    34261 gttcgatgtt gctttttaag attttcatcg acatttccgt atgggaagtc acatagatta
    34321 tttttcctaa aggatctaat tcacggatca atttaccgat cgctacacca tccatttcac
    34381 tgtcttctag ttcgatatct aaaaagtaaa taccaaaaga agaagttctg atcttggctg
    34441 cattgagaag ttcttccgga tcagaggtag aaatatggac ataactgtct aagttttcaa
    34501 tcatgattct atttttgatc accgttgata aaacttctaa ttgttttgga tcgtcttcac
    34561 aaatataaat gggaatcata tcattactcc tttattttat ttgtatataa atcgtttgag
    34621 aaaaacgctg gttttcaatt gatgtttcaa ggaaaagata aggattggtc tttgtcaatt
    34681 catccaagat aaacaagcca aggccttcgt tttttggatt tgtttttgtt gagaaccctt
    34741 tttgtttcaa ctggtttaac ggtaatgtat ttgttgttgt attgatcaca cgaatcatca
    34801 cggaatgatt cttcttgagt atggtcaatt cgattttttt cttctttgca gcactagctc
    34861 cttcaatcgc attgtccaag ataataccaa gcatacgtac aaggtttacc gtatgtttcg
    34921 tatccagttc gattggctca ggaaaatgaa gctggacgat caaccctttt tcctgtgcca
    34981 tcatgagttt taatgacagt aaactacgga tctcaggaac tttcatatta tccaacatac
    35041 ttagattggc cggaaaaagg ttcatcatct ggcgtgtagg taatatcgtt tgatcataat
    35101 aagaccgtaa tccttctaag tcgccttctg aaatatagct gtgaagagaa aaaagcagat
    35161 tttggtaatc atgtttgaat tctctcaagt cttgatagtt tttttctaga tctttgatat
    35221 aatcctgttg catcctgact tgttgctcta ataactgatc agctaatttc ttattagaga
    35281 ttttccaata ataaaccaag atgatcaggc caacacacag atatagaatg aaaaaactcg
    35341 tattcaaagc taagacatca ggtgtttcac cagaaaaacg ggtataaaaa ataatgatat
    35401 agtatgtaaa taatatcaat gtcccgatcg taccgatcat acggcggtcc acagtgtgaa
    35461 accaagtctc taacgatttt tttaaacaaa aagctaataa agcagataaa aaagcggata
    35521 agacaatgtg aaaatactgc aatgaatctc ctggttcaat aaccgaagat ttcaaaacaa
    35581 aaaaatcgcc gatgcttgtt aagtgatctc ctaaaagcga cgtcaataac ccaaaaggaa
    35641 gcgcgtaaac caattgttga cgcgaagtcg aaaagaagaa aaaagtaagc atcagcattc
    35701 ctatagcaat tagagcagta aaaatcccta aaatcgaata gacccatcca atcaaaatac
    35761 aagaaatcag aatgactccc gcaaacagat atttgtatcg gatgtgatgg tcaatcaata
    35821 agatacaaat tgtgtaaatc aaatattgca acgctatgga ccataaaaac ataaagtaca
    35881 gctcccattg atttttacca aattatagca caattggcgt attatttttt taatttttca
    35941 gggattttga attcagaact cataccaaag cagcagccag atacaaaaaa gtcagataag
    36001 ttagttaatt gtttaatgat tgtttttttc atgaaagatt cctccaaaat tcatcaagta
    36061 gtttgtaata ggaagcaacg tagctatttc taaaacaatc ccaagtagca aataggtaga
    36121 aaagtaagaa gctgagaaaa ataacgtaat gagagaaaaa attagaaaca tgctgatcgc
    36181 cttctttaat aatgggggac gtttctcggg ttcaatggga ttgattgctg tacctcttga
    36241 tccatagcga agcagtaaca aaaagcagct gattaacaaa aagaccatca ttgggaagga
    36301 gatagtcaat tgcagatgtt tcatcaccaa gggaacgccc cataaataaa gtagtgtcca
    36361 cagcagacaa acgaattcag agtcggaatg caatccataa gcatatctgc ggatgcagat
    36421 ataagaaaga aaggtgattc ctgtttccgc ccatgagcct gtcaccagag aaaagactag
    36481 aacgaccgct agttttccaa gattattcaa taaaacttct aagacaaatt ttacttggac
    36541 atacaccata tcttcttccg atttgtctcc gctgaataag gcttctaata atttgttcac
    36601 aactttatct ttcatctcat acgtacctcc accacaaatt ttatgctaaa aaaaataaaa
    36661 aacgtctttt gtttcataaa aagtggtttt gacatcaaaa ccgtcatgat ctcctaaaaa
    36721 aatcttcgtt ttccaagaac cttaccaaaa aaagtgacag ttttgatacg aaaagtactt
    36781 tttatgacaa gtttgtgctt tttcgagtga tttatgttaa aaaattactg accttataaa
    36841 aggtgatgga gggattctta tggaaaatga acaattgttt gaagtcggcg aaacatatgc
    36901 atttaaatct gatttatttg aatcaccaat aaaaggaaaa atagaaaaaa tctatgaaaa
    36961 tagtgtgatg atacgtgtca tgaaatgcgc agtagaagac aatgataccg ctcataatct
    37021 gcactggcag ttagttgtac gcaaatcaag tacaatagaa gaataaaaac agataaaatg
    37081 ttgagagcat aaagaggttg tgagtctccc gtttagctct gagttacaag gaataatgtt
    37141 aaaaaacagc ttttcatgtt ttatgaatat tgccttgtga ccgaggtgtt ggcaggagaa
    37201 tactgtttat ttgaaaaaag ggctgcgaca agacttttgt cacagccttt attttcatga
    37261 ataggagtta cttttggcta cttttagaga agtagctttt aaggagcaga taaagtcaag
    37321 gcttttattt ctataaatga agtagtaaaa tgaagaacag attttattac aggaaggatg
    37381 ccgataattg tgatcattgt tgcaggaacg atcggtgcag ggaaaagcac actaactgaa
    37441 atgcttgccc aagatttaga aacaaaacct ttttatgaga acgtggaaga taatgaagta
    37501 ttgccgctat tttattctaa tccagaaaag tatacttttt tattacagat tttctttttg
    37561 aacaaacgct ttttggcaat caaagatgct ttcagccatg atgacaacgt actagaccgc
    37621 tccatctacg aagatagtat gctgtttcat ttgaatgcag atttagggcg tgtttctgaa
    37681 gtagaagtaa agcagtatga aggtctttta gaaacgatgc tgaaggagtt agaagaaatt
    37741 tcgccacaaa agaaaccaga tctactggtt tatattcgtg tatcctttga aactatgtta
    37801 gcgagaatca aaaaaagagg ccgggaatat gaacagctag aacaagatcc tgaactctat
    37861 tcctactata aagaactcaa tcgacgatac gaagagtggt atgaacagtt tgatatatgt
    37921 cccaaaatag tgatcgatgg ggacaaatat gatttcgtag ccgatccggc atgtggagaa
    37981 caaatcgtac aagaaatcaa gatgcgggca aagaaaatga cagaagaggc agatgcccag
    38041 tcgatccgct acactacaaa taacccgaaa gcaaagggaa tctttacaac taaataatat
    38101 aaaaactaag caaattgctc actcgcagat atttctctgt gagcagcatc ttgcttagtt
    38161 tttttgattc attgagatca aatagtgaac cgattcgtat gataaaattg ccataaatga
    38221 aatgtctgag tgagggccat gatcaaaaat aaaatggaaa cgatcaaaat cgaatgggcg
    38281 ccaaacagat gatgacagaa aacaaggaca atagctcctg cgataaaggc aagaacgaca
    38341 cttagatagt ggaaaaatcg atcaaaatct gctttttctt tagaaataca ataatcatat
    38401 aagttcgttg ctaccccttt taaatttcca gttgtaaata aattagtgta ggcacgcccg
    38461 ttgattttat caaaagctac ccactggatc gatgcagtaa aagcaatcaa aatcgttact
    38521 aatgcgggat gctcatggac gggtgtcaaa ctaacaaaga aaaaaatcac tgcttcataa
    38581 tatagaacaa acaagcgcca gaaatgtttt tctttttttc taaaataatc aattagatac
    38641 tttgttagaa gaatccctaa gaaaaagaaa agggtagaca atactttttt accaacactt
    38701 agccattctc cgtcaaatgc ttggatgatc gatagaatga tattgccagt ttgagcagag
    38761 gcaaaagcac catattggat ataagtataa ctgtccatgg ctcctccgat aaatgtcagc
    38821 aaaagtccta ttgtacgccc ctcgtgaaag gaagtctgca tttttttcat caccttttat
    38881 gaatattttt gtcttcctta tcttagcata aacgattgaa aaaaaggaaa aattttcaga
    38941 aaactaaaat catatcgctt cccattttca tttttagaaa ggtctgttag tataaagaaa
    39001 aaatagacaa cgaaacttta aataaccaac ttgaaataaa caaattcaaa gaagaaagat
    39061 gggaaggaaa tcaatcagtt gaatgaaaaa gaaattctcc gattacaaaa agaattgaaa
    39121 cgctgggaga acaagtataa aaagcttcaa caagtctttc ggctacaaga agaaatcatt
    39181 gctacctatg aagcggctta tggcgaagca cccggactta ttgaggaaga agtacaagta
    39241 aaagaaagtg aaggaaacag ctctttcttt aaaatgatgg agaaacgttc ctataatcgc
    39301 ttcaatcaag aacaaaaagc agctatcaca tatgatatga agaaacatct tcgaatcata
    39361 gcaggagctg ggagcggcaa aacgcaaaca atctgtgcaa aagctgttta tctgatgacg
    39421 caaaaacaag tagacgaaga acgcatacta atgatcactt ttacaaggaa cgctgcaaat
    39481 gaactaaaaa aacgagtaga taatttcagc cagagaaaaa ccgctgtcca tatcggaaca
    39541 ttccatagta tcttttttag gatatacaat gaaatttgtc gaaaatttcc tgaagtagca
    39601 atgcaaggaa tacaaggaga cttttcaaag gatactgcac aaaaagtgaa tgctgttttg
    39661 caacagctga tacgtaaata taatctttat atatttgatc aatatggaga aaaaacgatt
    39721 gcttctcggt tagactattg gcagaatatg aacctttcag tagaagaaat ggttcagtta
    39781 gttaaagaaa aatatgattc cattgataag aatgcacgac agccgatatc agaacgactg
    39841 tatggattgc tcacggaact ccaagaacaa aaaagaagcc agcaattgct agagttcaat
    39901 gatgtactcc aaaatctgaa aagcgctttg gagaatgagg agatccagca ttatatcggc
    39961 caaaaatatg attatctatt cattgatgaa tttcaagata ctaatccact tcaatgggaa
    40021 atcgtgaaac ggatgacaaa ggaaaacagg atcaagttga ttgttgttgg agatgatgat
    40081 cagagtatct atggattcag aggatcagag ccagcataca tcaagaactt tgaaaaagaa
    40141 tatcctacca aaactctttt cttattaact aattatcgtt ctcgggcagc tattgtccaa
    40201 ggagcaaata gattgatcag ctataataaa aatgatcgga taccaaaggc gatgattcca
    40261 gcacaaaaag aagcaggtgt tatggaagcc tatttgtttt ctgatactaa agcagaaagt
    40321 cagtggctaa tcaaacaaat tcagacattt attcaaaaaa atgggaaata taaggaatca
    40381 atcatattat accgatcagc ttcacaaacg cagcagcttg tccaatctct gctgaaaacg
    40441 aatattcctt ttgtactgga agcagatagt ccatatgaag gtatctttgg tatcaagtct
    40501 ttccaacatt tctatcaaaa aattgttcat tggcaaacag cactgaatct gcaaaagaaa
    40561 aatcaggcct accagcaatt gctccggcag ctgatggcag actgctacct gaaaaaaagt
    40621 gaatgcgatc aatacttttc tcctaaatat caaaatatag ccgttgcaga ttatattttg
    40681 tcgataagcc ccaatttaaa atcgaaatct gcagaaatcc gagagtttga ggaagcgttg
    40741 cgtaaaacag accagcatca agaaatctat tcgcttgttc aaagctatct tcatctgcca
    40801 cgtatagcta aggaaatcga ccagagtgat caagaatgga tacgagaaga agtaaagcag
    40861 catgctactt tcagaagact ccaagcctta tcgcaagaaa cccaagcgac agctaaagaa
    40921 ttaaaaaccc gcttgattgc ttacagacaa ggaaaacttg atgcactatg tatccagagc
    40981 attcacaaaa gtaaaggtct tagttaccga aatgtctttt tgattggttg taacgaagga
    41041 agtttgcctt ataacggagc gacagaaaag aaagtaatcg actttaatga aataaaagca
    41101 gaaccagtaa cgacgataga agaagaacga agactatttt atgttgcgat gactagagca
    41161 agaaatcgtc tgtatctatg tgtacctcaa atgaaaaatt caagaaaatt gaaagtatcg
    41221 agatttatca aagaaaccgg gagtcgtgtg aaaaaaggaa agtgatagaa gagagggtgt
    41281 gacagaagtg gtcagtttca agaaagaaga aggaatgtac gaaaattgct tctcaaattt
    41341 ttgtgaaatt tcagcttatt ttcgaagaag ctatttctgg aacacagttt attcggaaaa
    41401 gggaggtgtg acaagaattt tgtcacacct cccttattta ttttgaaaat gagaatacta
    41461 ttatcaaaat agagaatata tagaaaaatt ctcattattc aaacgtaaat aatcagttat
    41521 tttgattttt tttatatttt attagctaat aattggtatt ttaaaagaaa ttactgtaga
    41581 attggattat aattaaaaag gagtgagaaa atgataaaag tatatacttc gcctagctgt
    41641 acttcctgta gaaaagcaag agcatggttg caagcgaatc aacttgaatt tgaagagaag
    41701 aatatttttg ccgaaccgtt aacagaaagt gagatcaaaa agatcttggc agcgactgaa
    41761 ggaggagttc aagatattat ttccactcgg tcgaaaattt acgaaaagct gggcatagat
    41821 tttaacgaat taactttaaa gcaaatgatc gtcttattca aagaatatcc ttcattattg
    41881 agacgaccta ttttgattga tgaaaaaaga atactaatcg gatttaatga agatgagatc
    41941 cggtcatttg tccctcgtga aattcgatgt gttgccagaa atctgatcta tttacaaaac
    42001 aataacatct taaattcata gggagggagc cttcgtggaa gtgaaagtct atggatcagc
    42061 gcactgtgta acaagtctga aggcgaaaca atggttagaa caccatcaat tgccttatca
    42121 atttgttgac ttagaagaac gcgatctaag tacagaagaa gcagaagaat tatgcagttt
    42181 tgaagaagtg caagcagaac agctatttgc gacttggtct gaggcttttc acaacattgc
    42241 gattgacctt tcctgtgtag gaaaaaaaca actgattttt ttatgcacac aacataccaa
    42301 tctcctcaga cgtcctttga ttattatcga tgaagttcta tttattggat acaatgagca
    42361 gttgatggaa cagcttatct taaataaata gactttaact gttttaatca agtcactgag
    42421 catttcatac agttgtaaca gtcgaacact tag
//
LOCUS       DAFELK010000019        41917 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFELK010000019
VERSION     DAFELK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.020"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            152..427
                     /locus_tag="LP433_001254"
     CDS             152..427
                     /locus_tag="LP433_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBL2005429.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            433..1200
                     /locus_tag="LP433_001255"
     CDS             433..1200
                     /locus_tag="LP433_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBL2005430.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            1368..3197
                     /gene="typA"
                     /locus_tag="LP433_001256"
     CDS             1368..3197
                     /gene="typA"
                     /locus_tag="LP433_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBL2005431.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            3458..5230
                     /gene="recQ"
                     /locus_tag="LP433_001257"
     CDS             3458..5230
                     /gene="recQ"
                     /locus_tag="LP433_001257"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBL2005432.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLRKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            5344..5646
                     /locus_tag="LP433_001258"
     CDS             5344..5646
                     /locus_tag="LP433_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBL2005433.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            5649..6812
                     /locus_tag="LP433_001259"
     CDS             5649..6812
                     /locus_tag="LP433_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL2005434.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            6838..10266
                     /locus_tag="LP433_001260"
     CDS             6838..10266
                     /locus_tag="LP433_001260"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBL2005435.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            10287..11411
                     /locus_tag="LP433_001261"
     CDS             10287..11411
                     /locus_tag="LP433_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005436.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            11401..11838
                     /locus_tag="LP433_001262"
     CDS             11401..11838
                     /locus_tag="LP433_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL2005437.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            11822..12160
                     /locus_tag="LP433_001263"
     CDS             11822..12160
                     /locus_tag="LP433_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBL2005438.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            12279..12839
                     /gene="rsmD"
                     /locus_tag="LP433_001264"
     CDS             12279..12839
                     /gene="rsmD"
                     /locus_tag="LP433_001264"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBL2005439.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            12836..13327
                     /gene="coaD"
                     /locus_tag="LP433_001265"
     CDS             12836..13327
                     /gene="coaD"
                     /locus_tag="LP433_001265"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBL2005440.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            13317..14360
                     /locus_tag="LP433_001266"
     CDS             13317..14360
                     /locus_tag="LP433_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBL2005441.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            14519..15247
                     /locus_tag="LP433_001267"
     CDS             14519..15247
                     /locus_tag="LP433_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBL2005442.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            15363..15608
                     /locus_tag="LP433_001268"
     CDS             15363..15608
                     /locus_tag="LP433_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL2005443.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            15605..15823
                     /locus_tag="LP433_001269"
     CDS             15605..15823
                     /locus_tag="LP433_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBL2005444.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            15959..16498
                     /locus_tag="LP433_001270"
     CDS             15959..16498
                     /locus_tag="LP433_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBL2005445.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            16491..18764
                     /locus_tag="LP433_001271"
     CDS             16491..18764
                     /locus_tag="LP433_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBL2005446.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            18802..19848
                     /gene="holA"
                     /locus_tag="LP433_001272"
     CDS             18802..19848
                     /gene="holA"
                     /locus_tag="LP433_001272"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBL2005447.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(19937..20191)
                     /locus_tag="LP433_001273"
     CDS             complement(19937..20191)
                     /locus_tag="LP433_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBL2005448.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(20591..20860)
                     /locus_tag="LP433_001274"
     CDS             complement(20591..20860)
                     /locus_tag="LP433_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005449.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(21330..21785)
                     /locus_tag="LP433_001275"
     CDS             complement(21330..21785)
                     /locus_tag="LP433_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBL2005450.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(21923..23851)
                     /locus_tag="LP433_001276"
     CDS             complement(21923..23851)
                     /locus_tag="LP433_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL2005451.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(24048..24881)
                     /locus_tag="LP433_001277"
     CDS             complement(24048..24881)
                     /locus_tag="LP433_001277"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBL2005452.1"
                     /translation="MFFANIIKAVILGIIEGITEWVPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(25073..25777)
                     /locus_tag="LP433_001278"
     CDS             complement(25073..25777)
                     /locus_tag="LP433_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2005453.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(25800..26426)
                     /locus_tag="LP433_001279"
     CDS             complement(25800..26426)
                     /locus_tag="LP433_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2005454.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            26752..29127
                     /locus_tag="LP433_001280"
     CDS             26752..29127
                     /locus_tag="LP433_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBL2005455.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(29151..29642)
                     /locus_tag="LP433_001281"
     CDS             complement(29151..29642)
                     /locus_tag="LP433_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBL2005456.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            29829..30749
                     /locus_tag="LP433_001282"
     CDS             29829..30749
                     /locus_tag="LP433_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2005457.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            30903..31247
                     /locus_tag="LP433_001283"
     CDS             30903..31247
                     /locus_tag="LP433_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBL2005458.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(31437..31937)
                     /locus_tag="LP433_001284"
     CDS             complement(31437..31937)
                     /locus_tag="LP433_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2005459.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            32465..32548
                     /locus_tag="LP433_001285"
     tRNA            32465..32548
                     /locus_tag="LP433_001285"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32499..32501,aa:Leu,seq:cag)
     gene            complement(32872..33510)
                     /locus_tag="LP433_001286"
     CDS             complement(32872..33510)
                     /locus_tag="LP433_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2005460.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            33845..34279
                     /locus_tag="LP433_001287"
     CDS             33845..34279
                     /locus_tag="LP433_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2005461.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            34302..34622
                     /locus_tag="LP433_001288"
     CDS             34302..34622
                     /locus_tag="LP433_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005462.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            34763..34954
                     /locus_tag="LP433_001289"
     CDS             34763..34954
                     /locus_tag="LP433_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005463.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(35025..35282)
                     /locus_tag="LP433_001290"
     CDS             complement(35025..35282)
                     /locus_tag="LP433_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBL2005464.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            35440..35703
                     /locus_tag="LP433_001291"
     CDS             35440..35703
                     /locus_tag="LP433_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005465.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            35727..35915
                     /locus_tag="LP433_001292"
     CDS             35727..35915
                     /locus_tag="LP433_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005466.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(35998..36183)
                     /locus_tag="LP433_001293"
     CDS             complement(35998..36183)
                     /locus_tag="LP433_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005467.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            36398..36769
                     /locus_tag="LP433_001294"
     CDS             36398..36769
                     /locus_tag="LP433_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2005468.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(36919..36991)
                     /locus_tag="LP433_001295"
     tRNA            complement(36919..36991)
                     /locus_tag="LP433_001295"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(36956..36958),aa:Gln,seq:ctg)
     gene            complement(37037..37465)
                     /locus_tag="LP433_001296"
     CDS             complement(37037..37465)
                     /locus_tag="LP433_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005469.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(37525..38283)
                     /locus_tag="LP433_001297"
     CDS             complement(37525..38283)
                     /locus_tag="LP433_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL2005470.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            38578..38775
                     /locus_tag="LP433_001298"
     CDS             38578..38775
                     /locus_tag="LP433_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005471.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            38881..39363
                     /locus_tag="LP433_001299"
     CDS             38881..39363
                     /locus_tag="LP433_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005472.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(39421..40017)
                     /locus_tag="LP433_001300"
     CDS             complement(39421..40017)
                     /locus_tag="LP433_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL2005473.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            40404..41870
                     /locus_tag="LP433_001301"
     CDS             40404..41870
                     /locus_tag="LP433_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBL2005474.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        13834 a         7141 c         8488 g        12454 t
ORIGIN      
        1 acaggcgaaa cgcaactgaa aaatcagttg cgttttgttt tttagaatta tcaataatat
       61 tattatgtaa acttaaaaat atgacaactt cttggtttat taccacttcc tatgctacac
      121 tgaagaggaa tatgaaatag gagagttgaa gatgcaagaa tatcagtatc cacttgattt
      181 agattggaca acagacgaaa tggtcattgt aatgaagatg tgggaagatc tggaacgtgc
      241 gaatgaaaaa gggataaaca atgaagcttt tttgaagact tatcagcagt ttaaaactgt
      301 tgtcaaatcc attggtgagg aaaaacgatt gggacgggaa tttgaaaaag cttccggtta
      361 ttctttatat cgtacagtgc agcaagcaaa aaaaaatcca aacaaaactt tgagaatgaa
      421 cgggtgagat aaatggaaca gatgattgat catatcaagt cctggcttga agaagctggt
      481 gagaaaatca aatcttctca acaaacatta acaatctcgc aaaaatcaaa tcgaacggat
      541 ctagtaacaa atgtcgatcg aaacatccag aattttctaa tcgaaaaaat ccattccttt
      601 gatccagagg cgaaaatatt ggcagaagaa gaagggtgta atcaattatc ggatctcgat
      661 ggaagagtct ttatcatcga tcctattgat ggcaccttga attttgtgat tgaaggggaa
      721 aatttttgta ttatgctcgc tgtttatgaa tccggcgttg gaaagcttgg tttcatttat
      781 gacgtgatga gaaatgaact tttttggggt ggaaaaggaa taggcgtgta taaaaatgat
      841 gagccattgc ctagaccagc aaataaatcc ttatcggaag gcttacttgg tgtgaatagt
      901 tatcttttcg gtcataataa atatggaatc cgagaaattg cggaaagcag catggggaca
      961 cgtatgtacg gatgcgctgg tcttgaacta gtggcaatct tgaaaggaaa ccacattgct
     1021 tatatttcaa accttagccc ttgggattat gcagcgggaa atgtcttatt ggaagagttt
     1081 ggtatggtaa caagcggtct ttttggtact cctttgacat ttgaaaaaag ggaatactat
     1141 ttagcaggga cttcttgtgc atatgcagaa atcgcagacc ttttgaaaaa agaaggctga
     1201 aaaaaaggta gaaatcattc acaaaaatga taaaaacgag caaaagatta attttctcga
     1261 aaaaatgaaa acattttact atatttcatg aaaaaagtct gctataatta gcagtcgagt
     1321 aaaatttgcc ctgtcataaa gaaccaataa aaaaggagtt agttacattg aattatagaa
     1381 acgatatccg taacgtcgca attattgccc acgttgacca cggaaaaaca acattagttg
     1441 atgaactatt aaaacaatca gatacattag acgcacatac gcaattgcaa gaacgtgcga
     1501 tggactcaaa tgcgctagaa aaagaacgtg gtatcacgat tttagccaaa aacacagctg
     1561 tagactataa aggtattcgc gtaaacatca tggatactcc aggacacgcg gacttcggtg
     1621 gcgaagtaga acggatcatg aaaatggttg acggcgttgt gttggtcgta gatgcgtatg
     1681 aaggaacaat gcctcaaaca cgttttgtat tgaaaaaagc actggaacaa catatcacac
     1741 caatcgttgt cgtaaacaag attgacaaac cttctgctcg tcctgagcat gtcgtagatg
     1801 aagttcttga actattcatc gaattaggag cagatgatga tcagttagac tttcctgtga
     1861 tttatgcatc tgcactaaat ggtacgtcaa gcttgtcaga tgatccagca gatcaagaac
     1921 caaccatggc acctattttt gatacaatta ttgaaaaaat ccctgctcct gtcgataaca
     1981 gcgacgaacc attacaattc caagtttcat tacttgacta caacgattat gtaggtcgta
     2041 tcggaatcgg acgtgtattt agaggaacaa tcaaagtagg agaccaagta gcattaatta
     2101 aattagacgg aacagttaag aaattccgtg taacgaaatt atttggtttc tttggactaa
     2161 aacgtctaga gattcaagaa gcaaaagctg gagacttgat tgctgtctca ggtatggaag
     2221 atatctttgt cggtgaaaca gttactcctg tggatcatca agatgcgtta cctatccttc
     2281 acattgacga accaacattg caaatgactt tcttagttaa taattcacca tttgccggtc
     2341 gagaaggtaa attcgtaacc gctcgtaaga ttgaagaacg tttgatggca gaacttcaaa
     2401 cagatgtatc cttacgagtt gaaccaacaa actctccaga tgcatggaca gtttctggtc
     2461 gtggagaatt gcatttgtct atcttgattg aaaacatgcg ccgtgaggga tacgaattgc
     2521 aagtatctcg tccagaagtt attgaaaaag aaatcgacgg tgtaaaatgc gaaccgtttg
     2581 aacgcgtgca aatcgataca ccagaagaat atatgggtag tgttatcgag tccttgagct
     2641 tacgtaaagg tgaaatgcaa gatatggtcc atacaggaaa cggacaaatc cgtttgacat
     2701 tcttaacacc tgcccgcggt ttgattggtt attcaactga attcctttca atgacacgtg
     2761 gttacggaat catgaaccat acttttgacc aatatctgcc aatgcttcct ggtcaaattg
     2821 gcggacgtca ccaaggggcg cttgtttcga tcgatacagg aaaagcaacg acttattcta
     2881 tcatgagtat cgaagaacgc ggtacagtct tcgtagaacc aggtacagaa gtatatgaag
     2941 gaatgattat cggggaaaac agccgtgata atgatttgac tgtcaacatc acgaaagcaa
     3001 aacaaatgac aaacgtacgg tctgctacta aagaccaaac atctgtcatc aaaaaaccaa
     3061 aacaattgac gttggaagaa tctttggaat tcttgaatga tgatgaatat tgcgaagtaa
     3121 caccagaaag cattcgcttg agaaaacaaa ttttagagaa aaatgctcgt gaaaaagcat
     3181 ctaaaaagaa aaaataatct gtaaaaggat gaagagagaa accagcttgt tataaaaaat
     3241 agctggtttc tttttttgtc caactctttt ctgtggagaa gtcatctttg tcaatggaca
     3301 taaattcaga aaatacgccg aaagacgttt aaaagacttt taaaaaactt atttctagag
     3361 agtttttgtt tcataataag ataatgtttc acgaaaggag atcaacttgt ccttcgaaga
     3421 aaatcgaagt aaaatggcaa gagaaaggag cgggaagatg aacgacttat taaaacaata
     3481 ctttggctat gatgagttta gacctggtca aaaagaaatt atccagaaag tcattgatca
     3541 ggaaaatgta ttaggaatca tgcctaccgg aagtgggaaa tcaatctgtt accagcttcc
     3601 agctttacta ttagatgggc ttactgtggt tgtgtcccct ttaatctctt tgatgaagga
     3661 tcaggtggac gcggcgaatc aattaggtat acccgccact tttatcaata gctcgttaga
     3721 tggttacgaa acagctagac gcttccaaga aatcgataga cagcagtacc gtttacttta
     3781 tatcgctcct gaacgtttta tcatgccgga ttttatccaa gcaatgaagc gatggaacgt
     3841 ccgtatgatc gctattgacg aggcacattg tatctctcag tgggggcatg atttccgccc
     3901 aagttattta cagatggcga accagctaga tcaactgcca aatcgtcctg taattgttgc
     3961 tttgacagct acagcgactg tgcaagtagc tgctgacata aaaagacttt taaaaattcc
     4021 agaaaacaac catattcaga ctggttttga acgagaaaat ctacgatttc aagtaattaa
     4081 agatcaaaaa aaagaacaat atctaatcga atatttaaag atcaacaaaa atcaatctgg
     4141 tatcatttat gcagcaacga gaaaagaagt agaccgtctc tatcatttgc ttagaaaatt
     4201 cgatttttcc gtgggtagat atcatggtgg tctaaatgag aatgagcgaa cagaaatgca
     4261 agaagccttt ttatacgatc gcttgcagct gattgtagcg acaaatgcat ttggtatggg
     4321 tataaataaa agcaatgtcc gttttgttat ccattatcaa attcctggct ctctagaagc
     4381 atactatcag gaagctggtc gggcgggaag agatggtctt tccagtgaag ccatcctgct
     4441 tttctctcct caagatatcc aagtccaaaa gttttttatc cagcagtccc aaagagaaga
     4501 agggcaaaag caaaaagaat atgaaaaatt aaaagcgatg acagaatacg tgtatattga
     4561 gtcctgtctt cagcaataca tcctaaacta ttttggcgag acaagcagtc cgtgcaaccg
     4621 ttgtggtaac tgtttagatg acagagaaat agtagaagta acgacagaag cacagatggt
     4681 tctttcttgc ttaaaacgta tgggtgagaa ctatggtaaa caaatgctga tgaaagtctt
     4741 agcaggatcg aaagaacaaa agctgcaagc tttaggtttt ggacatttat ctacctatgg
     4801 actgatgaaa aaccaatcgc aaaaagaaac gatgcagtta attgaatatt tgatatcgaa
     4861 tggctatctt ctgaccatca atggtgagta tcctgttttg aaagtaacag aaagagggat
     4921 acaagtattg aaaggacaag aatctgttta tcgaaaggaa cccaagaaag tccagcagct
     4981 atcggatgaa gaaaccgata cactatttga agtgctgcgg gaactgcgaa cggatctagc
     5041 atcagaagca ggcgttcccc cgtatgtcgt attttcagat tccacattga aagaaatgag
     5101 ccgaatacgt ccatcaagca gattggagat gcttcagata aaaggagttg gccaaagcaa
     5161 gcttgataaa tatggcgaag cctttttatc tcggataaaa aatgcggact ctaacgttct
     5221 ggataagtag aaagaacgaa tacgtaaaaa tgaataaaaa caactggtta aatctgtttt
     5281 ttttgctcct tatgaaaatc aaatatgtta taattaagga attagaatgg gaggtaagca
     5341 cagatggatt ctttgtcgaa aaaacttgcg atccaagtat taaatgatga agcagaacgg
     5401 atcaaacgat taatccgaaa tcaaaacaac agtctctgta tctcacaatg caaagccttc
     5461 gaagaagtgg tagatacaca gatgtacggc ttttcccggc aagtcggttt tgctgtccgt
     5521 ataggagtaa tcggaaagaa cgagggccag ctgatgttaa gtgagctaga acgagaattg
     5581 aatcagttat atagtgaggt ttaccaagaa atttatgata aaaaagaagt tggcaaggag
     5641 gaatagactt gcctaagaaa gtgaaaaaaa ggcatctatt agactatagc atcttgattc
     5701 cctatttaat tttatgtgta ttgggattga tcatggtata tagttctacg tcgtatctat
     5761 tattagaaaa cggacaaaat ccgtccgcat cagtcattaa ccagagtatt ttttgggtgc
     5821 ttagcttgat tgctatcgca ctactttata aaatgaaaac agatgttttg aaaaaccagc
     5881 gtttgatcat ggcagccatc gcagttttga cgattttgct gctgattgtt gtgttttttg
     5941 gtaaggagat caatggggcg aaaggttggc tgcaaattgc aggattctcg atccaacctg
     6001 ccgaatacct aaaaatcatt tctatctggt acctgtctct gactttatct aaaagacaaa
     6061 acagtgtaca aaaagatttt cttgggactg tgaaacgtcc acttgcaatg gttatcggac
     6121 ttactgcatt agtcgctatt cttcccgatt ttggtaatgc ggcagttatc tttttgatta
     6181 ttttggttct gcttttagcc agcggagtca attatgtgta tactttgatt gtaggagtag
     6241 gaggcttttg tctaagtact tttacgatct ggctgatcaa tatcacaaac ggaaagatct
     6301 tacccggacg tttacagtat atctataatc gatttgctat ttaccaaaat cctttctcag
     6361 acgaattaaa taaagggcat caactagtca acggctacta tgccatgttc aacggaggac
     6421 tatttggcag gggattaggt aacagtatcc agaaaaaagg atttttacaa gaagcacaaa
     6481 ccgattttat ttatgcaatc gtagtggaag aactgggagt gattatgggg attttgatat
     6541 tagcgttgct attctttatg attgtgcgca ttgtccttgt aggtatccgt tcaaaagatc
     6601 cgttcaattc gcttttgtgc attgggatcg gcgcaatgtt tttgatccaa gtatttgtca
     6661 atcttggagg gattactggc gttattcctt tgacagggat cacgttccca tttttaagtc
     6721 aaggaggctc cagtttgctg atgctttcga tttgtgtcgg ctttgtcctc aacatcagtg
     6781 cggatgaaaa acgcaagagc ttaggtttat aataaaaaaa gatgtaggag tggttcgatg
     6841 aaaaaagttt tagttgctaa caggggtgaa atcgctgtac gtgtatttcg tgcttgtaca
     6901 gaattaggaa ttaaaactgt tggaatctat gcagaagaag atgaatattc cgtacaccgt
     6961 ttcaaagcgg atgaagcata tttagtagga caaggaaaaa aaccgattga tgcgtatcta
     7021 gatattgaag ggatcatttc tatcgcgaaa gaatgcggag ctgacgctat tcatccgggt
     7081 tacggtcttt tgtcggaaaa cttgaatttt gcgcaacggt gcgaagaaga aggcatcatt
     7141 tttgttggac ccaaactgca tcatttagat atttttggag ataaaatcaa agcaaaagct
     7201 gcagctatcg aagcggggat tgcttcgatt ccaggcacag atggaccaat cgcttctata
     7261 gacgatgcct tggagtttgc gaaacaatac ggttatccga ttatgatcaa ggcagctcta
     7321 ggcggcggcg gacgcggcat gcgtgtagct cacgatgaaa agagtgcaag agagggctac
     7381 gaacgtgcga aaagcgaagc aaaagcagcc tttggtagtg atgaagtgta tgttgaaaaa
     7441 tacatcgcta atcctaagca tatcgaagta cagattctcg gggatacgca tggaaacgtc
     7501 atccatcttt ttgaaagaga ttgttctgtt cagcgccgtc accaaaaagt agtagaagta
     7561 gcgccttgtg tctctatgaa tgaacagcaa cgtcaaaaaa tctgccaggc agctgtccaa
     7621 ttgatgaaat atgtcgggta tgtcaacgca ggtacagtag aatttcttgt tgaaggagat
     7681 gatttttact ttatcgaagt caaccctcgc gtccaagtgg aacatacgat cacagaaatg
     7741 attacagata ttgatatcgt aacaacgcaa ctgttgattg ctcaaggttt ggatctgcat
     7801 aaagaaatcg gattgcctca gcaagaagga attaaattaa atggttcagc cattcaatgc
     7861 cgaatcacta cagaagaccc gttgaataac tttttaccag acacagggaa aatcgatacg
     7921 tatcgttcac ctggtggttt tggcgtacgt ctggatgtcg gaaatgctta cgcgggctat
     7981 gtagtgacac cgtattttga ttcattgcta gtaaaagtat gtacgcatgg tgctaccttt
     8041 gaaacagcca ttcagaaaat ggaacgttgc ttgaaagaat ttagaatccg tggagtgaaa
     8101 acaaacattc catttatgct caatgtcatc acacatcctg aattccaatc aggaaatgca
     8161 aaaacaacct tcattgatag tacagcaaca ttatttgaat ttcctcgact acgagaccgc
     8221 ggaaacaaaa cgatgaaata tatcggtgaa attactgtga atggttttcc aggtatcgaa
     8281 agtggcgaaa aaccatttta tgaagaacca cgtatgccta aagatctaat cacaagaact
     8341 gattacgtaa cggctaagaa tgtattagat gcgaagggtg ccgatgcttt ggtcgaatgg
     8401 atcaaaggac aggaaaattt gttgttgacg gatacgacat ttagagacgc ccatcaaagt
     8461 ctgctagcaa ctcgtgttcg gacaaaggat ttcaagcaga ttgcacgttt gactggagaa
     8521 ggtcttcctg aactcttttc aagtgagatg tgggggggag caacatttga tgtggcttac
     8581 cgctttttga atgaagatcc ttggcaacgg ttgagaaaaa ttcgttcttt aatgcctaat
     8641 acgttgctgc aaatgctttt cagaggttca aatgccgttg ggtattctaa ttatcctgac
     8701 aatgtattgg tggaatttgt caaagaagca gcagcgcaag gaatcgatgt atttcgaatc
     8761 tttgatagtt tgaactggac tccacaaatg gaaaaaagta tccaagctgt acgggatact
     8821 ggtaaaatcg cagaggcagc tatttgctat actggcgata tcaacgatcc aagtcgggca
     8881 aaatacaatg ttcagtatta taaagacatg gcaaaggaac tagaacaact gggtgcgcat
     8941 atcattgcaa tcaaagatat ggctgggctg cttaaaccgc aggcagctta tcgtttgatt
     9001 agtgaattga aagaaacgac agatctgcca atccatctgc atactcatga taccagcggg
     9061 aatggaatca tcacttattc tgctgcttca aaagcaggag tagacatcgt tgacgtggca
     9121 atgagtgcaa tgagtgggaa tactagtcag cctagcatga gcagcttgta ttatgcactg
     9181 gtcaatggtc cacggctgcc agaaatcacg attgaaaatg cacagaaatt aaaccattat
     9241 tgggaagatg tgcgcatgta ttacaaaccg tttgaaaacg gcttgaatgc tcctgaaaca
     9301 gaagtatata tgcatgaaat gccaggagga cagtattcga atctacagca acaggcaaaa
     9361 gctgtcggat taggtcatcg ctgggatgaa atcaaacaaa tgtatcatac tgtcaacttg
     9421 atgtttggcg atatcgttaa agtaactcca tcatctaaag tagttggaga tatggcacta
     9481 tttatggtcc aaaatgatct tacagaagaa gatatttatg aaaaaggcga aacactaagt
     9541 ttccctgaat ctgttgtgac tttcttccaa ggagaactag ggcaacccgt tggcggattt
     9601 cctaaaaaat tgcaaaagat tattcttaaa ggcagacctg cattgaatga acgtccaggt
     9661 cttttggctg aatcagtcga cttcaacgaa gtaaaaaaag aattggcaga aaaaattggc
     9721 tatgaaccaa aacaagacga agtattaagc tatttgatgt atccgcaagt ctttttggac
     9781 tatcaaaaag catataatca atttggcgat gttacattac tggacacacc aacatttttc
     9841 caaggtatac gtttgggtga aacaatcaat gtacaaatcg aacgcggaaa aacgcttatc
     9901 attcgtttag atgaaatcgg agaacccgat atcgaaggga atcgcgtact gttcttcaat
     9961 ttgaatggac aaagacgtga aatcactatc aaagataatt cgatcatcag tacggtccaa
    10021 acccgattga aagctgaacc gacaaaccga gaacaaattg gagcaacgat gtctggttct
    10081 gttttggatg tattagtgaa aaaaggcgat aacgttaaaa aaggtgatac gttgatgatt
    10141 actgaagcga tgaaaatgga aacggccatc gaagcacgtt ttgacggaga agtcgcacat
    10201 gtatatgtgt cttcaggaga cactatttcg tctggtgacc ttttgattga agtgactgag
    10261 aaataataag cgaaaggtgg ggaaacatga aaagactggg tttgttttgg ctgattctgc
    10321 tattagttat tgtggcattc tacatggaac cagtcttgtt tccgccaaaa cttgaagtga
    10381 aggaaaactc tgatcaacaa atatcaaacc aaatgacaac gtggaaatac caggagctta
    10441 aagcaactgg tttttctact tatatcggaa aaccgatcga tcagctggaa aaggattttg
    10501 gccaagccta tgatcgatta actagcggat ttggttttga aacaagatat tatgaaaata
    10561 aagctagtca tctcacattt gaagcgaaca tccaagacag cagagtcaca actgttaaag
    10621 tactgcaaac agggcctgct gatatcgcgc cgttttattt agggatgacg atgcaagatc
    10681 ttacgaaaat cactactatc tatactaatt tcacttttga gtaccatgat acagaagttg
    10741 gaatcgaact aatggaagag gatatgaatt atcgtccgct aattgctttt gataacgaca
    10801 cttttgctat tttatttttt gatcaaacaa caaacggcct attttcagtt gtgtatttag
    10861 ataaagatag tcttttgaaa ctattgccat atcaagtgtt tggtgaaggc cttccacatt
    10921 atcaagcaga taaatcggct gattgggaat caatcaatcg cgttaaagaa cgaaaaagta
    10981 cgactttatt aaatatgctt agaagagaag acgaacttcc catatacaat caaacacttg
    11041 cctttcaaaa ccacagtcag ctgctactac atgatttttt gacaaggcct gaggaaatat
    11101 tgtcagagga acgtatggct gattggcaaa aatcgctagg cagtgctcaa acgacagtga
    11161 aattctcact gacgaatgat gaattggaga agttaatcag taaacaaaaa ttagaaaata
    11221 ctagtgggct atttattcat ccggcgattg acgctacttt ttcgttttta tattggtaca
    11281 gcgatcctta caaccatgac cgtttcatgg acccgggaac ggattctgta ggcattgctt
    11341 tttctaaaga aaatatgtta gtcttattgc aagaagaaaa cggagaaagt agtgatagca
    11401 gtgatcgtta acgaagagct gtttcaactg gaggatcaat gcctccaagt cgctgaaatg
    11461 ataaaaaaga gtaaaacgat ggcttcttat cttgaacata aacagtcaat ggaagaatct
    11521 gcaaaagttt gccagttgaa agaagcgttc ttgtctaaga aagaagcatt tgaaaatgta
    11581 gcggcatatg gtgagtatgc acctgattat cgtgaaaaaa aacgagctgt tcgaaaagca
    11641 aaaagacagc ttgatatgga tgagcatgtt gcagctttcc gatatagtga aacacagctg
    11701 caaagtctgt tggatcaaat tgtccaagta cttgccgaag aagtttctaa tgaaatcaaa
    11761 gtagatgcag gtagcccgtt ttttgaaacg aaaaaacact ttggatgcgg aggtaattgt
    11821 catgcaatta gacaatagtg aatttgaaat aacaaaacga cgcgggctga tcgtatgggt
    11881 ctacagctta aaacaattaa agaatctgaa aaagttcggc ttgttgcatt atgtctcaag
    11941 aagaatgaaa tatgtcgtgc tttacttaaa tgaagagaca ttggaagaaa cagaagaacg
    12001 aatccgtaaa ttacattttg ttcgaaacgt agaacgttct taccgaccgg atatcgaaat
    12061 gaattttgcc gaaaaaatag gaaacaaaac agtattaaaa gacgaaggtt tcgaaattga
    12121 agagctaaat acagaaatcc gattagctga acatctttaa aaatctctta tgagcagttt
    12181 ttaaataaaa aataacttgg ataacgatcg atttttgatc attgtccaag tatttttttg
    12241 gtatactagt accagtacca tttctaagga gtgagtagat gcggataata tcaggaaatt
    12301 atggcgggcg ccgtttaaaa agtttagcag gggcgaacac cagaccaact acagataaag
    12361 taaaagaatc catattcaat atgattggac catattttga tggagagaca gtattggatc
    12421 tgtttgcagg aagcggtggt ttagctatcg aagcagtatc tagaggctgc agtcatgcgg
    12481 tatgcgtaga caaaaattac caagcgctaa aaatcatcaa agaaaacatc gaaattacga
    12541 aagaaccaga gaaatttacc acaataaaac ttgatgcgga caaagcaatc gaacggctag
    12601 cagcggagaa acaacaattc gactacttgt ttcttgatcc gccatatgca aaacaaaaaa
    12661 taatcgatca aatccataaa atggaagaac tgggactttt ttctaaaacc gcagttatcg
    12721 tatgcgaaac ggataaaaca gtcgaattgc cagaaactgt ggctggattc catcaaataa
    12781 gaaaacagat ttatggcata acggccgtaa ctatctatag aaaagaggga aatcaatgaa
    12841 acgtgcatta ttcccaggaa gttttgatcc ttttacaaaa ggtcacttag atacggtgga
    12901 acgtgcggct aaattattcg atgaggtagt aattggtgtt tttatcaata cttcaaagaa
    12961 aagtttgttt cccccagaag aaagaatgac attgatcaca aaagctgttt ctcatcttcc
    13021 taatgtaaaa gtcatgcatc aagaaaatca attgacggta gaaacagcaa aagagattgg
    13081 tgcagatgcg ttgatcagag gcatacgaag tatcaaagac tttgaatatg aacgagagat
    13141 tgctcagatg aatcatcatc tatatgatga attggaaact gtcttcttat tagcaaaacc
    13201 agaatatagt cacgtgagtt ccagtatttt aaaagaagta ctgcactttg gcggagatgt
    13261 gagcagctac ttaccgccag tgatcaacga agctttagct ggaaagcgtg aatcaaatga
    13321 aagctaaaca atggttgaaa acagtactga ttatcatatt tggaatgttg atcattggat
    13381 ttgtagtagt tcccttgccg tattatgtag aatcaccggg agccacgatc gatctgaaag
    13441 aactaattac ggtcaatgat aaggaagata aaggttctgg gtctttctct cttacctctg
    13501 ttggtatcag gcaagctaca ggtttcttag ctttaaaagc taaaatgacc ccttttgaag
    13561 aattgatcag tgaagaagaa ttgactggtg gggcgacaaa tgaagaatat aatcaaatgc
    13621 aacagtatta tatggattct tcccaaaatg cagcaatcga acaagcgtta aaacttgcag
    13681 acaagcctta taaaatggaa ttcaaaggcg tatatgtcat gagtgtagag aaaacatcga
    13741 atttctttgg caagctttca gttggagata cagtaacaaa agtagacggg aaaagctttc
    13801 aaagtacaga agcatttatg gattatgtaa aaagccaaaa agttggacaa acaatcgaaa
    13861 tcagttattt gcataatggt gaagaaaaaa cagcttctgg tgatctgatc gagttaccaa
    13921 cagataaaaa ggcaggaata ggtatcacgc ttactgacca taccgagatc gaatcagata
    13981 cagatgttcg tattaattct ggctctatcg gtgggccatc agcgggattg atgttcactt
    14041 tagaaatcta tgaacaagtc actggtaaaa acttgcgaca tggtaagcaa attgcaggaa
    14101 ctggaacgat caacagtgaa ggagaagttg gccgaatcgg aggaatcgat aaaaaagtgg
    14161 caagtgcgga taaagctggc gtagagattt tctttgcacc agatgatacg atttcagacg
    14221 atgttaagaa agaatatcct gaaataaaaa ccaactacga agaagcaaaa gctgccgcta
    14281 aaaaattgaa ttcctcaatg aaaatcgtac cagtaaaaac agtacaagaa gcgcttgact
    14341 atctagagaa aatgaaatga aactaaataa ttaaagaggg gttgtgacac gagttctgtc
    14401 acaacccctc tttttcgtca aaaatcttca cgataaaaat aaaaacaaaa gaaaaaattg
    14461 acgtaattag atgttgaagg gacgattttg ccagagctca ctgtttcttc aattttaaat
    14521 gaaaggagta atgaatgatt tttactggtc attctttgaa aaaagaacaa tgatagaaaa
    14581 aatcagcaag aaaatactag cttcacccaa attgatcatt tggatgtcta tgatagttct
    14641 tatcttttgt atcgcaagtg gttttttatt atcaaatttg ctattttata gagaaacaga
    14701 agagactgct gcaaaagaaa tactttcttc gtttagttcc agtggagaag atccatcagc
    14761 tgaaggaaac gatgtagaag aggatgctcg tccaaaggtc atgtacaccg atatcaaagg
    14821 aagtgtgaag gagcctggta tctattcctt ttcttcagaa gaacgggtct atgatgtact
    14881 aaagcgtgca ggtggattat tagaagaagc ggatagcgat cgaatcaact tttctgcgaa
    14941 gatagaagat cagcaagtcc tatatatccc tgctgtaggt gaagagctgc cagaacatct
    15001 tgatcagttg gcatcctcgg aaggaaaaca gcctacagca gattccgagc ctcccaaaat
    15061 aaatatcaat acagccactc catcagaact tcagcagatt cctgggatcg gatcagtcaa
    15121 agcgcaagaa atcattcgat ttagagaaga aaacggatcc ttccagaaag tggaagacct
    15181 gcaggagatt tctggtatcg gtgaaaagac agttgaaaaa ctaaaaaact tcgttacaat
    15241 taaatagaat gattcaaaat cgactggcac gagcaataaa tggacgctaa tggatactaa
    15301 gaataatcca attctaagag cttggcagga cgaggaggta gtatttttgg ataggaaata
    15361 gcttgattgt tcgcaaagaa acattaaaaa aaccaatgct gaatgtctat ctccaaaata
    15421 aaatatctgg gattcatatt atgaatacgg ctgtcagcgg caataacagt caagctctac
    15481 gagaacgctt tgccaaagat gtacttagct atacagcaga taaagtattt attctcattg
    15541 ggacgaatga tctagcagag cataaacaac tttctaaaga aacgtaccaa aaaatctgca
    15601 gtggatgata gttcagctga aaaaagacta tagttctgat catgctttct ttatcacgcc
    15661 accagcagtc gatgagacaa aacaaaaata tcggaataac aagttgatca aagaatatat
    15721 ctctgttctc acagaagtag caaaacgcca tgattgtgaa gtatcgattt ttatacggaa
    15781 tttcttgaac aaatggattc gaagaatttt tataatgggc taatggatga cggacttcat
    15841 ttcggcagtg aagggtagga tcttttgtca gacaggatga ttcgttatat ttaaagaata
    15901 ttttgtttaa gcaatgagta ctttttaatc aacttgaaaa aacggaggaa tataaaacat
    15961 gttagaaaaa tcttcaaaag catgcgatac gaataaagaa aaagttactg ataagtcaca
    16021 taatgaacgc attccttggg accagtactt tatggctcag gcagtactgt tatctttacg
    16081 tagtacgtgt acacgtttag aagtaggagc gacactcgtt cgagaaaaaa ggatcattgc
    16141 tggcggctat aatggagcag tcagtggaga tgtccactgc atagatgaag ggtgttacgt
    16201 cgtggatgga cactgcttgc gaacgatcca tgcagagatg aatgcactcc tacagtgtgc
    16261 aaaacttggt atcccgacgg aaggttcaga aatctatgtc acacattttc catgtttggc
    16321 ctgtacaaag gctttgttgc aagctggtgt gaaagggatc aattatctcc atgactatcg
    16381 aaatgatcct tatgcccaag cgttgatcga acaattaggt gtatctgtac accaagttgc
    16441 tttagactca cagcattttt caaaacttca aaatgaatta acaggaaaac atgtctagcg
    16501 ttttagaaag gcatgttcga aatcggttga tttttccggc aattacgtcg atgattatct
    16561 gtttgttgta ttacactgac aattggggtt atcgtttgct tcttgccgga atttttttat
    16621 ggttttcgct aaaagaagga cgttttatcg cgtacttgtg tattttgtgt agcataacgg
    16681 tatccatttc ttataggcta caagagtatt catttttaga ggaaaaaaca acatctgcgc
    16741 aaattactgt atttacagat acgattcgtg caaatggtaa ttttttgaca atggaaggaa
    16801 ggttatcaga gaataaacaa aagctccagc tttcttatca agtaaacaca gaagcagaat
    16861 tgaaaacatg gcttaacttc cgaggaaagg gaatagaatt gactgctgaa ggcgagttca
    16921 tctctccagc aaaaaagcgg aatctttata attttgacca agaagcttac ttcaggaacc
    16981 atagaatttc tggacggttc caaattcaaa agattgaaca gatcaccatg caaaatcact
    17041 ggcgaaactg gcttcagaga aaaagaggat cttttatctc ctttgtccaa tctgaatttc
    17101 cgcaaaaaac aagtgtatat attaattctt tattatgggg ctataaagat gcaggattca
    17161 gagaaccaga agaaattttt agggagagtg gtttgctgca tctgttcagt ctatcgggtc
    17221 tacacatcca attttattta gggtggctgt attatttatt tcgacgtatc ggatggccac
    17281 tacacgtcag tattattccg ttgagtctac taactatctg ttatgtttct attgcaggaa
    17341 gttctatttc tgttttgcgt gctagtttgc tgtttttatt gcgattgcta gtcaaattgc
    17401 tgaataagca ttattccacc atggacttat ttgcagttgt cttttggctt cttttactat
    17461 ttgatcctcg atttcttttt catgcgggtg gacagcttag ttttttcatg agttttttgt
    17521 ttatcctgat ttcttttgat ggagattggt tgaaaaaaac ggcctctcac gtcctgttta
    17581 ctatgatcac gatgccgttg attgtatggc atttttatga gtggcctatt ttaggtagtc
    17641 tttttacatt actgattgca ccggtattca agtttctttt tcttcctggt gtgttatttc
    17701 tcacactctt caatcgctgg ctgccggaaa ctttactttt gctgatagaa gagggattaa
    17761 tcttatttga gcgaataatc gatttttctt cagggtcgtc tctcattata ggacgtttgc
    17821 cccttgtgct atctgggatg tatattttcg gattactgat ttgtatggat aggttgaaag
    17881 aacaacctgt gaaacacttg ttttatgttg gtcttttttc ttttattttt ttgactttgc
    17941 catttttacg cttttcttca acgatcgctt ttatcgatgt cggtcaagga gacagtatct
    18001 ttttgcaaag tccttttcga aaagaaacga ttttgatcga tactggaggt cagttacact
    18061 ttgaaagaga aaagtgggcg caaggtatga tacgtcctcc tgctgaaaga aatatcgttc
    18121 catatctaaa aggtcagggg ataagtgtaa tcgataaact catcttgaca cacgacgata
    18181 cggatcatgt gggagaatta cccacgttat ctcagcattt tactatcaaa aaaatttata
    18241 tcggttgggg cgctggacga aatgagccat tacaaaggca tttatctgaa gctcaaaaaa
    18301 atggtactga gatcattgaa atcaaacatg gggacaggat cagcggttat tatgatcttt
    18361 atgtattgac tccttttgaa aagggagagg gaagaaatga agattcgatt ggtctatgga
    18421 tggaatataa caataggcgc tttttatttt taggagattt gaatcaagca atggaaaaac
    18481 aattgctttt gatttatcct aatctgaaag ccgatgtagt caaattaggt catcacggta
    18541 gccgtacgtc aagtaacaca gattttcttt cccatattga agcaaaacat gggattatat
    18601 cctgcggcgt aaataatcgt tatggtcacc cgcacagcga agtattggag acactagaag
    18661 aaaatcagat aaaaacatgg cgaacggatc aacaaggaat gatcacctat cgctggcatc
    18721 cagtttttca tcctcatggg ctagtggaaa caatgataga ctagtaattc tcatctgctc
    18781 atggtaggat aatttttgaa agtggtgagt aatttgagta tacaagcaga gttacaaaaa
    18841 atacgtaaag aaaaacttgc atcttgttac ttgattttag gaacagaaaa gtttctccaa
    18901 gatcaagttc ggacagaaat tgtcaaaaaa atccaattag agggcgaaga tgacttaaat
    18961 tttttaagtt ttgacatgga aaatgcaagt ttagatgagg tagtagctga agcagagacg
    19021 ttgccgtttt tcggagatca acggttagta ttcgtagaga atccttattt tttaacaggt
    19081 gaaaaagtaa acaatggaat cgaacaaaat actgatttat tgacggctta tttgaaagaa
    19141 ccattagaat cgactgtatt agtattcttt gcgccatatg aaaagttgga tgaacggaaa
    19201 aaagtaacga aacaattgaa aaaaacagca attatcatca atgtccaaca gttgaatgaa
    19261 aaagaagtac gtcaatatct gatgaatacc ttagagaatt cctcaatcaa aatggaacga
    19321 agtgcaattg atttattctt gaggttgacc gacttagatt tatccaaaat gatgagagag
    19381 ttacagaaat tggtccttta tggacaaaat caacagcaaa tcacggtaag agaagtagaa
    19441 gaattagttc ctaaaacgtt agaacataat atttttgaca tgacccaata tattttaaaa
    19501 gggaagacgg aacaagcttt gcgtttatac gaagatttag ttatgcaagg ggaagaaaca
    19561 atcaaaatta atgcgatttt gctttctcaa ttacgtttat ttttacagac aaaatttctt
    19621 gtaaagattg gttatcagca ggcaaatatt gctgaaacat tgaaaatcca tccatatcgt
    19681 gtaaaacttg ccatgcagga agtaaaaaaa ttcgatgaac atttgctggt acagttgttt
    19741 gatcaattag ttgagatgga ttatcaaatc aaaacgggac aaatcgaaaa agaattaagt
    19801 tttcaactat tcgttttgcg cacagggcag ttgttaagaa atcgataaga agaaagacga
    19861 gggcaaagca tgcgggaagg tcgtttgttt ttgtcctttt tttgacaaat aaaaaaatcg
    19921 gccgaagccg attcttttat ttagcgattt ttttgcttaa acgagatttg tcgcggttag
    19981 ctttgttttt gtggattaga ccttttgatt cagccatatc aatagcttta acagcttctt
    20041 tatataacgc atctacgttg tcagcacctg aagctacagc atcttcaaat tttttgattg
    20101 cagtacgcat agcgcttgtt tgagatgaat ttttcacatt agcgttttcg cttgtacgaa
    20161 cacgtttgat tgcagattca atgtttggca ttagtttcac ctccgataac ttaagttctt
    20221 acgcgtgtta ccgcataatt caacattcat tattatacct aaaggcagcg tgctttgcaa
    20281 tatgaacatg acaagttttt ttccttaaca gtcttttatt aggatttttt ttcagtaaaa
    20341 acggatagta caagctgaaa aaaatcaaaa agacgctatt gtgggaggca atagcgtcaa
    20401 accaaactag atttttattt atctatttaa acaaagtttg aatgggaatg tttggtacta
    20461 agttattata taacaaagag aaccgtttgc aaagtttttt ttgaaaaggg atacgattcc
    20521 ctgttgttct ttgtttttct attaagaaac tgcagttatt ttataaccag tatcctttga
    20581 tcagtaaagg ctattctggt gtaccgatta ttttaatgta ttcatcgata ttttttatca
    20641 acattttttt tatgaccaac tggttccgac ggttccattt gccacttact tccagcacat
    20701 atttatttag gggcaaacgt aagatatatt ttgccaaata gcgatcttta agcaggccat
    20761 tgatcacacg gtcctcaagc tgcaagttga tcccagtcag catcattggc tgttcttgta
    20821 aaacgtacgt atcaattaaa agaccttcaa aagtttccac aagcgtcttc ctttcttttc
    20881 aaagtaacct gaaaacaggc actaattctt ccattttgat attcgttgaa gtggatgcga
    20941 tcattctttc ttttgtccac tgtaatctag tataacaaaa aagagcagaa gagccaaaaa
    21001 gaaaaaagag catcgaattc tataggaagt ctcattggca cggcctaaat tattacaaaa
    21061 cattgattaa aaaaagcccc tgcatcgcag gagcatcccc tatatcgttt taataggtca
    21121 atcaaaaagc agtatcaaac acattttgta tcaaatcagg aaataataga taagctaagc
    21181 ccagaatcaa aagtaccgct agaagaaacc agccgattgt tcctatgaaa tactttaatt
    21241 tttcgaacat tgtatcacct cgttgtcagt atatcacgga tcagtaaatt gggggtgtta
    21301 agaatctcct aaaatagaca aaatttgttc tattttccta aagcaaatac ttgtaagata
    21361 cagtaagtga taccagaagc aatgaccggt ccggcggcga ttcctcttaa gaagacaaca
    21421 cctaaaatcg tgccgaaaac aagtgcaaca gtgatttgtg gatcagaagc aatcaatcct
    21481 acacccttgg aagataagac agccactagc ccaccgcaaa aaacagctac ccagccaata
    21541 ggggatttaa aggcttctaa tagatcacgt agaccgattt ctcctgttgc gatagggatt
    21601 agaatagccg ctgtgatgat cgtcacccca atattgattc ctttgccttg aagccaaggg
    21661 aaaaaggaac gggaggctgg tatgagcttc ataatcaaaa caaaagctgc cgctatcatc
    21721 agactttgat ttttagctaa aattgctaca agtaaaataa ttcctaaaaa aagccaactt
    21781 tccatgaaat atattcctca ctttcttcga aacaatcata acatgttttt agaaagttac
    21841 aaaagtagga attcatcctt caagacctat tcataagctg tttttttcat aaaataaaca
    21901 aaatcataaa aaaacacttt gcttatttga cagaagacag ccgcgctttg tatagtggac
    21961 aagacttaca tttttttgaa gaatcagaaa gatcaggtaa aggtcttagt aaacgcaagc
    22021 cattcagaat aaccaatatt gtgcttcctt cgtgtcctac aactccaaga ggtagattta
    22081 aaaattgcag gaagttagaa gcaatcaaca agagaataac aagaatcgaa aaaataatat
    22141 tttgtttgat gatccgccgc atttttaaag atagccgatg actgtagaca aatttattta
    22201 agtcgctttt cattaagacg atgtctgcga tatccatagc ggcatctgtc ccttgcccca
    22261 tagcgacacc taaagaagcg gctgctaaag caggcgcatc attgactcca tcaccaacca
    22321 tcgcatttac ttggtaaagt tcattctctt ttttgactag ttgtgttttt tcttccggag
    22381 tacagcttgc atagtaatgt tcaatcccta cttgttcagc aatggccttt gctgtgccag
    22441 aatggtcgcc ggttatcata cttgtatgga tgttttggga tttaaagtag gaaattactt
    22501 gttgggtatt tgcttttgga atatctagca gacctaaaac agcaattaac tgctgatctt
    22561 tagaaagata aatcacggtt ttgccttgat tttccaaacg ttcgatcatt tccgcaatct
    22621 ctttgctgat tatcatcgtc tcaggatcat atgcgtgctt gccaactttc cattgcgcac
    22681 ctaaataggt agtttgtaat ccaaaaccag taatttcttc tattggtaag tattggattt
    22741 cttcaggtat tgtgcaatcg aaatattgca aaatcgcatg agcaagtgga tgcgtcgttt
    22801 tttgttccat agcaacaaga agttgttgtg ccaaatcctt ttcatcaaag aaaaagctgt
    22861 cagttacaac tggttttcct ttagtgagcg ttcctgtttt atcaaaggca atcgctttta
    22921 attcagaaag cttttctaaa tggataccgc ctttgattaa aatcccattt tttgcagaat
    22981 ttgaaagagc agctagagaa gctggtgtag cagatgcgac aagcgcacaa ggagaagcca
    23041 caactaataa taccattcct cgataaaagc tttcatccca actccaacct aggaaaaagt
    23101 gggggagaag gatcattaga ggaacagcaa gcaaaatcaa ttttacataa ttattttcga
    23161 ttcgttcgat aaatgaagct gtttgagttg gcgtattctg cgcttcttct actaattgga
    23221 taatcttagc aaagacagtt tcggaactcg tttttgttac tcgaatcgtg atgggatttc
    23281 cttgattcag cgttcctgca tacatctcat cgcctaaata tttttctaca ggcacagatt
    23341 caccgcttaa tgcagactca tcgatcgttg cctgtgtgct ttctaaaaag ccatctatcg
    23401 gaacagctgc tcctttagcg acaaatacca agttatccac ctttagttga gaaacatcta
    23461 cttcttgcat ttgtccattt tcttttaata attgggcttt ttgtggttga agattcatca
    23521 aagcagtaat ttctttttga cttttattag ttgtgtattc ctctaatgca ccgcttaaac
    23581 aaaagatgaa tgtcaacatt gctccttcaa agtaattacc gatcaaacag gcaccaatag
    23641 cagctaaagc catcaataaa tccacattca gtgtccgatc attccacaat tctttcaagc
    23701 cttccgatgt ttgtttatat ccaccgatga taatggcact gatataaaaa agtggggtga
    23761 tggtaagaga gaatcggtcg aagataaaac cgaagatcat aaataaaagg cagccgattg
    23821 ttgctgcaaa agcttttttc tgattagtca tcgttattag acctccttgt caaaacaagg
    23881 atagcataat aaaaatgtaa ttgataataa taacagctaa atgagaacga taatggttat
    23941 catttggtga ttaagcttga tgttgttttt attatttata atgattatta ttaaagaaaa
    24001 taaaaaacca gaacatttct caaataagag aagtgttctg gttttttcta cattgcaata
    24061 aaccaataac caatcaaaat gataccaagg ataatacgat accagccaaa agcggtaaag
    24121 tcgtttttct tcaaatagct tagtaagaat ttgatagcta agacggaaac cacaaaagat
    24181 acgaatgttc ctacaagaag aacaacagtt tcttccattt tgaatgaatt cccttcagct
    24241 aaatatttga cgatcttcaa gccgcttgcg ccaaacatga caggaatccc taagaaaaat
    24301 gaaaactctg tagcgacaaa acgcgaagca ccaatcaaga tagatcctag gatcgttgcg
    24361 ccagaacggg atgttccggg aacaagtgcc aagacttgga ataacccaac aagaagagct
    24421 gcttggtacg taaagtcatt cagagaagtc caacgaggtg ttttgttttt gttgcgtttt
    24481 tcgacaataa taaaggcaat accgtaaacg atcaaaacaa tggcaactgg taagaacttg
    24541 tggaaatttg cttctaacca atcatccaaa ggcaaaccaa tgatgatggc tggtatgcaa
    24601 gcaacgatca ctttaaacca aagtgtccac gtatcttttt tttctaccgt tgatttactt
    24661 ggagaaaatg ggtttaactt gtgaaaataa agaacgacga cagccaagat cgcccctaat
    24721 tggataacga cattgaacat cgacataaat tgtgaactgg catccagttt gatgaattca
    24781 tctgctagga tcaaatgacc agtactactg atgggcaccc attccgttat tccttcaata
    24841 ataccgagaa tcactgcttt gataatattt gcaaaaaaca taaattcctt ccttcccaat
    24901 taagatacat cttatagtat accgttattt tttgagaaac ccaatctgtt ttttaatatt
    24961 aagaaaaact tgagaaataa agcagataag tacacgaaga gaaaaaagaa gacaaagccc
    25021 tcgttcagac tttgcctttt atgattctct ggtaaaaatt aaaatatccc cattatagaa
    25081 acgagtcgcg actatgtgtt ttcccgttat cgatataaga cgtatcattg atgccgtgga
    25141 tagaaaatcg accgtttgca taagtgacct ttgttacgct gccatttaaa agcccagcac
    25201 gaacaggctg tttaggatcg atcagattaa gcaaaaaggc gatcgtcaaa ccatgagata
    25261 cgactaaaac atttccacca ccattttttt cgcagtgatg ggcgatatct tcaaatcctg
    25321 tccatacacg gtctcgcaat gtttcataag tttccgccca cccagcggta tctaagttgt
    25381 atacagcatt agcaatttgt tcaaaagaaa cttctgtggt aaacatttca tcatatgttt
    25441 taaaattcaa tacacgaggg atcacacccc acatttccat gtcatatcca ccttcaagag
    25501 acccgaaaca ccattctcta atcctttttt caataaaata aggaatttct tttcccttag
    25561 aatgttctcc tagaataata cgggcagttt cgattgcacg accactgtca ctagaataag
    25621 caaatgaaaa gtcgacattt tttaacccgc gacctaaata atgaatgcct tcttgtcctt
    25681 gctttgtgag gggtgtatca caccagcctt gtactcgttc aattgtattg aacatcgttt
    25741 ttccgtgtcg tacgatataa agtgtagttt ctgtcatttt attctcctcc taagtcgttt
    25801 taacgattga aaaaaggatt tgtccttttt tcctgttcaa tcgtcgttgc atcgccatgt
    25861 cctggataga ctgcaaattc atcaggtaat acaaacagct gggtccgaat actatgaagt
    25921 aattgttcta aattccctgt atacagatcg gttctaccga tacttcctct aaacagggcg
    25981 tcgccagaaa cgacaaaatc atcaaaaata aagctgacgc ttcctataga atgccctggg
    26041 gtagggacga cgcgaaaaga catgtttcct aaagtataag ttttcatttc aaattcatat
    26101 tctgcaggcg agacaataac atcagcaata tcatcatgtc taccgagtcc agaaagattc
    26161 aaaatcggat cacctagcca tttttgctct agtgggctga cataaactgg gatttgataa
    26221 tacgcgcgta aaggttccac tgcaccgata tgatcgtagt gagtatgggt aagcaaaatc
    26281 gctaccggct gttggtttgt ttttttgatt tcttgtttga ttcgttccgc atcttctcca
    26341 gggtcaatga tcaaaagtgc ttcttcgttg tagaccaaat aacagttttc ttcaatcatt
    26401 cctgttttta atctttcgat atgcatgtgc attcctcctt gatagccaaa acttctttca
    26461 tccattagta taacgcattc attgctagga aacaaaaaca ggtacttatt tctctttact
    26521 tatctgaatt atcagactat atgaaaagta tttggatatt ctaaagagaa ggaaagtaag
    26581 ttttcatagc attttaatat gtccttgtta cattagattc atccaaaaat ccaaattcta
    26641 tatcctatat ccctgcctaa tcagcagggt gtttttttat gtttggaaag agagctcttt
    26701 ttgctaaact aggttttttc aggtaatctt agagagaaag aggtggtgga aatgatcaaa
    26761 cagtcaaaaa tatctgtgcg gcacttagta gaatttattt tgcgacgtgg aagtatcgac
    26821 aatcgtaaaa aaagtaacca tactgcatta gaaggagcga gaatccaccg caagctccaa
    26881 aaagatgcgg gagaaaacta tgaaaaagaa gtctttttaa aaacaacagt tcaattagat
    26941 gaatattacc tgatcgttga aggccgtgca gacggtattt tcaaaagaga cggtatttat
    27001 tatatagatg aaatcaaaac ctccgaacca cgatttgaag atttagaacc agaacaagtg
    27061 gaacttttct ttcatcaagc aagggtgtat gcctatatct atagtcaaga acatgattta
    27121 caagaaataa atctgcaatt gacttacttc cagacggcag aagaagtgat cacgagaaag
    27181 gttgaacatc agacaagaga gcagttagaa acttttttta aaaagctgac tgaagattat
    27241 aaagaatggc ttgtttttca agaaaactgg cgcactgtac gcaatgcctc tttgatggct
    27301 ttgaaattcc cccatgatga gtataggaaa ggtcagcgtg aactagcggt agctgcttat
    27361 aaaacgatcc gtacgaaaca gaaattgttt gtagaagcac ctaccggaac aggaaaaaca
    27421 atctctacgt tattccccgc tttgaaagct gtaggggaag aagagggaga aaagatcttt
    27481 tatctaacgg ctaaaacaat aactagacaa gtagctgaag atgctatgac agcattaaaa
    27541 gatacaggag ctgaagtaaa aagtgtcact ttgacggcga aagacaagat ctgcttttta
    27601 gatgagacga cctgtaatcc agatcagtgc ccatatgcca atggttatta caatcggatt
    27661 aatgaaggtt tatgggatct tttgaatcat gagaatcaga tcactcgtga agtcatcgaa
    27721 acttatgcaa gaaagcatac actttgtcct ttcgaactat cattagatgt cagtatctgg
    27781 tgtgacgtaa tcattgggga ttacaattat ttatttgatc caactgttta tttaagacgt
    27841 ttttttgaag atgaaaaaaa cgaggactat ctgtttttga ttgacgaagc acataatttg
    27901 gtgaatcgtt cccgagagat gtattcggca gaactatctt atgaaaaaac gaaacgaagt
    27961 aaggaagcta taccaaagga attcaaaaaa cttcatcgcc gtttcaacaa actattaaaa
    28021 gaatttgatt cgatccgaga aatagcaaaa gaagatcatt gggattatca tcatcaaaaa
    28081 gcaccggctg aatctttagt aaaggcaggt tatcaattaa gcgaaaaaat taaagaatgg
    28141 ctggcagaat ttcctgagca cccatcacaa gaacaattgc ttccttatta ttttgatttg
    28201 cttcattttt tgaaggtcag tgaattttat gatgatcact acgaaacaac agtcgaaaaa
    28261 acgtatcgcg atctgatagt aaaagagttt tgtattgatc caagcttgtt tcttgagcag
    28321 tcgttggata aaggaaaaag cagtattctt ttttctgcta gtttttcacc actctcttat
    28381 tatcaggaaa cactgggggg acaaaaaagt ctggcttaca aactgccgag tcctttccca
    28441 gaaggaaacc agcaagtttt catcgcaaat tacctagaga cgacttatcg aaaaagggaa
    28501 cacagtctgg caaaattagt agagacgatt catgcttttg ctgatggaaa ggtcgggaat
    28561 tatttcgttt tctttccttc ttatcaatat ttagatcttg cggtggaagc attcagacag
    28621 caatatcccg acagcaatgt gctaatccaa gaaacggaca tgaatgagga agaacgcgaa
    28681 cgatttttaa caaaatttca aacaaatccc gctgaaacat tgattggatt ttgcgtactt
    28741 ggcgggattt tttcagaagg aatcgatttg agaggggacc gattgatcgg cagtatgatc
    28801 gtaggtgtag gtttgccgca gatgaatcat gagcaggaac tgatcaaatc atattatgat
    28861 gagaaggaac accttggatt tgcttacgct tatcagcttc ctggaatgaa caaagtcttg
    28921 caagctggtg gtcgagtgat tcgtggcatg gcggatcaag gaatcgttgt attggcagat
    28981 caacgatttt ctagtttttc ttatcgacgt ttattcccac aacattggca aacagcaaga
    29041 gaagtacgaa gtgttgggga attggaagaa ggaatacagc gtttttggtt atcaaaagaa
    29101 gcagtaaatc aaaaaaacga ggaatgacag acgtcagcct cgttttttga ttaacgatag
    29161 ttagtgaatt gcaactcgat tggtaagtca agtttacgta ataaagcaat cacagcttgt
    29221 agatcatcac ggttcttacc tgtcactcta atctgatctt cttggatttg tgcttttact
    29281 ttcagttttt catttttgat agctgtagtg attttcttcg cgttttcacg atcgattccg
    29341 ttgaccaaat cggcagtttg tcgagctttg ccacctagag cgtgttctga ttcggaaaaa
    29401 tggatatttt tgattggcac atttcttttg atcagcttac caaataatac atctttgatc
    29461 tgttcgattt tgaaatcatc atcgctcaat acaactagat tgctgttctc taatttgatt
    29521 tctactgtag aatccttgaa gtcaaagcga ttggacaatt cttttgttgt ttgctgaatc
    29581 gcatttttta cttcttctgt attgacttct gatacaatgt cgaagctagc atcttttgcc
    29641 ataggaaccc tcctgatata catataaata tttaccatac atctatctta tcataggatt
    29701 agggcagatt cttacctgtt tgctaaaatt cttctcattt gagttcgaag tattttattt
    29761 taatagataa actgttattc ttacatttgg aataccaaag taggggagag gtgcttgtga
    29821 gtaaaattat gactgcgtat cataaaaatg aaagattaaa gaaaatagtg gttattttga
    29881 taaccggatt gaccgctgcg gtcgctttaa attatttttt gattccagcc aatgtctttt
    29941 ctgcagggat gaatgggatc gctcaaatca tttcctcgct tttatatgaa tggtttcata
    30001 tcaagataga cacaggaaca tttatttttc ttttgaatat ccctgtgttt gtattagggt
    30061 ttctcaaagt aggaaaacga gcaacgatcc ttagttttgt gaatgttgta tgtgtatcgg
    30121 tgatgacgat gctgcttcca gtcggacaga tcactgataa tattttgatg aatgccctag
    30181 taggcggtgt tttattaggt cttggcgtag gattatcttt aaaaatgggc tttacaactg
    30241 gtgggatgga tatcatctct cttgtacttt cacaaacaac tggaaaaaca gtcggaaact
    30301 acatgctgat tctaaatggt atcattgtag tcatcgcagg cttcttcttt aactgggaaa
    30361 gtgccttgta tacgattatt tccatttatg caatgactca agtaattgat gccatccaca
    30421 cgagtcatca aaaagtaaca gcaatgatcg ttaccgtcaa gccagaagag gtaacagaag
    30481 aactagcaaa acggatggta cgtggaatga cattactgcc gtctgtcggt ggctattcaa
    30541 aaaaacaagg gaacatgatc atgatggtca tcacccgcta cgaaatgtat gatcttgatc
    30601 agatcgttca tgaaatcgac gacgatgcat ttatcaatat tttaccaact cattcagtat
    30661 ttggccggtt tgcaaatgaa aacgaacaaa aaatgtatcg aacaactggc gtattgccag
    30721 aaataaaaaa tcgttcacaa aaaaaatgag gaatcaggtt tattttagaa taaatttaat
    30781 ctattacatc taataagaac atttttataa atttaaacga gaatcttact tctaaattct
    30841 catttacaag cagctaaaaa aagagtatga taaataaaaa tcgtgttaag gagtgtcgta
    30901 cgatgagcga agcaaaccaa gaacggtctg gacaagaaat agaactaatc aaagaacgta
    30961 ttcttgctgc cttggaaatg gtgattgatc ctgaattagg aatcgacatc gtcaatttag
    31021 gcttgattta tgatatagaa ttcaatcctg aaaatggaga aacagtcatt aagatgactc
    31081 taacaactat gggctgtcca ttagcagata ttttaacaga atctatccat gacgcattaa
    31141 aagaagtgcc agaagtaacg aaagcagaag tcaaactagt ctggtatcca gcatggacga
    31201 cagataagat gagccgttat gcacggattg cgttggggat acgatagaaa tcttggctga
    31261 ctagctatga gaagcaaata ggaaaaacaa aaaagccttt tatcctttct agaagaaaag
    31321 agataaaagg tttctttgtt tataaaattt tgtctgctat attataagtt aattaaataa
    31381 atgtgttcta ttgataaagg acattcaaat ccctttcctt ttggaatcct tcttttttac
    31441 atcagtttga ttttcgtata gtattctttc tcatcttcac gataaatcgc agccccattt
    31501 ttttgttgtg ctttaagact gccaagattt tttttattta cagacaaaag tgcctcatca
    31561 atgccgattt tttttgcctc ttgtagtact aatgctaatc cttgtgtggc atatcctttt
    31621 ttacgataat taggggagat gccgtaacca atatggccag cgccgtttct taatgtttcg
    31681 ttcagtttat ggcgcaaatt aaaaattcct acatactcat gttcatcact ttctaaaata
    31741 aagacggttg cgggaacgta actctcagga agatcgattc ctaaagacgt tttttcgcat
    31801 ttttttacat aatctaaaaa ttcagcaaat gtatagccat aagcattgtt gataaatcca
    31861 ctctcatttg gtccaaagct agtttgtagc tgataagctt tctttaaatc tgcttcccat
    31921 agtttgatca gtttcatcgt attcacctct ttaagtaacc ttattcattt gttttctact
    31981 atagcactat tgttgtaaat agccatgcct atttttattt attgtgtcat atcgtattaa
    32041 gaatcatcga acaatacaaa tatgaattac aataaaaaaa ttatttgaag ttcgttcatt
    32101 cgttacttat gatctctaga agaaagaaaa cgtgaattac ttcagcgtct agaattccag
    32161 aaggatagta atcaacagaa gaaataatca atatccaaat gaaagaagat agctgaatcg
    32221 agaaaaagag gaaaaaagaa atgaagaaaa aaataaaata gttactaatc ccagagtcgt
    32281 tcgtttaaca ttgaaatcga tcatatggat aaaacagatt ttttcaccaa ccctcaatag
    32341 atgatggagt tgctcggatg aattatttgt gtagatggca taagggaggg cgtacagaaa
    32401 tgaaaaagaa caaaaatatg ttcttgacaa aaaacacatg taatcctaaa ctaaaagatg
    32461 tgatgcggct atggcggaat tggcagacgc gctagcttca ggcgctagtg agggtgacct
    32521 cgtggaagtt cgagtcttct tagccgcata atttgttttt ttataaagag aaggtacacc
    32581 tggagcgatg agaaagaaaa taacatatta tctaaaagaa tataggaaaa attttaaaca
    32641 acggaaccag attcaaataa atcaaaaaaa atttgtgtga aggtgggaca gtttaaaacc
    32701 taatagattg attcaaatag tagatttata gattctgata caagaaatac tggcaaacga
    32761 tagttaagga ataaagacta aacttaaact caaaaagagg tcatgcgaaa gaataaatcg
    32821 catgacctct tactatattt tgaatgtgtt taaacgttca aataatgaat cttagtacca
    32881 accgtttgct tcccagaatg ctttcgccgc ttcccaagaa ccataacgtg aagtaacata
    32941 ttgttctgct actctttctt ggtttgcagc agagtagtca ccatttaagt aagaagaatc
    33001 taattggtaa cggccgatgt aacgtccgtt cgttgctgtg taagaaccgc ttgattcttt
    33061 ttgtgcgatc cattcttttg cagagcttgt acttgctgga gtagcagcag tttctgttac
    33121 agcaggagca ggttgtgttt cagcaacagg cgctgcttgt gtttccgttt gaaccgtttc
    33181 ttgtacaaca ggttgttcag cttgaacagg ttcagcttgg actggtgctt cttgaacggc
    33241 tgcttgaggt tcagcagctg cttgtgcaga gccttctgtt gggattgtta attgttgtcc
    33301 tgagtagatc aggttaatat cagaaattga atttgattct gcaatggcat tgatcaagga
    33361 gttatcacca acgtattttt gagaaatcgt tgatagagta tcacctgatt gaacggtata
    33421 agcttcgtcc gcatgagcag tcgttcccat gaagaatgca gcgccggcag ccaaagttgt
    33481 tccaaaaagt aaagttttaa gtgatgtcat gaaaaatctc ctttattcgt taaaaagttt
    33541 tatttgttgt gttcaacgag gaatacttta acacgtgaaa atatttcata ggtaaaagaa
    33601 gcatgacaat ttatgacaaa tccacgtttt ttgtaacaga atgatgttcg ctcgatgtga
    33661 aaaatgatga ggaatttcac ataatgcaga aataatggga ttagaacagg tgttctgatg
    33721 agaaaagaaa tgtataaata acttgaaaga aattgctttt gttcatcatt ttatttacat
    33781 attgcgtata ttttttgtat ttttgcttga gatgttacaa taaaagaaaa aggaggcggt
    33841 tccaatgagt aaaagatacc agaacatcat ggtagcagtt gacggatcaa gacaatcgat
    33901 caaagcgttc gctgaagccc ttgacttagc aaaggacaat gaagcccact tatttatcgt
    33961 gtcaatcatc aacaaagttg agctgaccca tagtgcctat gccttttcaa aaatctatgc
    34021 agatgaaaaa caaagaacag aagtagccat gctgaaaaaa atcaatgatg ccaaagagta
    34081 cggcattgct gagatccacg caatagttga aactggagat ccaagaaatt tgattgccaa
    34141 tgtcatccct ggacaagaaa atattgattt gatcgttatg ggagcgacag gaaaaggtgc
    34201 tatacaacaa gcattagttg gatcgaccgc ttcttatgtc gtatcacatg ccccttgcag
    34261 tgtgttggtc gtgaagtaat gagataaggg aggaatagaa aatggttcgt cctcaagaag
    34321 tccgtgcgcc aaaagaaaaa atagaaattt tagcaattat tgaagacggc acacaaacaa
    34381 agaagggata ctcgatcgct ttagtaaagt ggaaaggaaa aaaaggtgtt gctctgagat
    34441 gggatggaga taaccaacaa gataaaggat tccctgtcac agctaacggt tatcatccag
    34501 cgtggtttgt tctgcctgat aaatttatgg aattatacag ctatgattat gcaagagccg
    34561 cagcatcaat caaagcatta gataaattaa cagaagagca gaatgaaatg gaggaaaaat
    34621 aaaaaagacg aaccaatcag cctttagaaa actgattagt tcgaggagta aaaatgaaaa
    34681 aaggttattt gggatgaaac tagaataatg cgtataactt aaataaaact taaagcaata
    34741 aaatggcaag agggtgaggc aaatggaagc aggaaaagta ttacaggaag taaaagcact
    34801 atgtgcagat aaaaaatatg aagaagcgaa aagcctgatc gaaaagaaca aagaaaattt
    34861 ggaagaaaag tacccgatcg cacaagaatt tatagaatta aaacaaggaa cgatccttca
    34921 ccgattcaaa catttttttg gtataacaga atagaaaaaa cgattaaaga tcggcagaaa
    34981 tttgctgcat ctttaatcgt tttcttttta aacatgcgag ggattcaatt ctgattctta
    35041 tataaaaaat agatccaaat aataagaaaa attactgaaa gcgtcaattc gatgatgtgt
    35101 gttattaata cagacgttgt ttcccaatgc ctaaaagaaa aaatttgata agtaaaatat
    35161 acagcaggta aagaggccag taaaactgaa aacttctttt ttgtccattt tatgtaatag
    35221 aaaagaatgc ttatcataat aaaaaaagga atataaaaaa caaattgacc gatcgcgatc
    35281 atactattgc ctccgataaa taaagtccat gatacaaaat aacactttgt gcgaaatggc
    35341 gcaagcagtt ttgtggattt atccggtaaa atctgtatcg attttgaaat tagaggagaa
    35401 acttgctata atcaaagtga aagaaggagt gggattttca tggatcatgt agtgttagaa
    35461 atcgatttgc atttgatcaa taatattcgg gtgatttact atgttgtaag taacagtgtc
    35521 gaacaacgtg tactgacgaa taaaataaat ggtattttag caaagaaaga cgttcaccga
    35581 ttcaataatg gtgaaggaag ttattatagt atcccagtag aaaaaattat ttatacgaca
    35641 gtcaaagtca gagaagatct agataccaaa aaagcatatg aacctatttt tacaacttat
    35701 tgattgacag cagatggagg aaaaaaatga atccatatga acaacttatt caagatttga
    35761 tcgatggaaa aatcgaaaag attgatgtaa aaagagaaga attaatggct tttcgagaag
    35821 cgtggctgaa gttggagaat cgtaaatatg tggtgggaaa agcctcactg aacggcaatg
    35881 tgacttatca ttacgatccg acacgtttat tttagtatga agtattcaga aaagaaccaa
    35941 aggaggacga tgcagcagca ttgtcctcct ttgattttac aaaagtgaaa gttttactta
    36001 tttgaataga tttttaaatt tgtttttgac actgtcgata tttacatctt ttaaaagatt
    36061 ttgggctttc tctttataag gtcctaattg ttctttatgt tcttcgataa atcgttttgc
    36121 gccatcgaaa ttgccgttct taatcatttc cttgactttt tgaaataatt cttcttgatt
    36181 cattttgaac acatcctttg ctatcaacat gattttttac atggacaaaa cgagaaaaac
    36241 tgatttatcc acacgtcaat aatatcaaat aacgatcatt tttactaaaa aaacactcga
    36301 ttctcgcttc taaagtagga gaaaaatctc caacttggga cggatggaat ttctttaact
    36361 gacccatata ctgaatatat aacaaggagg tagaaagatg aaagtgatta aatatttgat
    36421 tggactggcg gcgattagtg gtattttgct atttggactg aaatattata ctgaaggaag
    36481 ttatggagaa atccctggta tacttgatca gctaaatcca ttagttgaaa aaggagaggt
    36541 ctatgtaaag acacaaaaac cagaggaagt aaatgaatat ggtacagcaa ggtatgtgca
    36601 gaaagctgct gatgccaatg ggaaagaacg aacggttgaa tttaatggtc tttctgtgtt
    36661 aaaagaaaat cattatttga aaattagcaa taaaggagca cacatagaaa cgtatgagga
    36721 agttcctaga gaaaaagttc cggagaaagc attagcaatt attgggtaaa tcagtttttg
    36781 tattaagaat acgcccgatt ttattattca taatttaatt atgtaaacta aattctagta
    36841 gtaaaaataa tacaataatc cccctgcaaa aagattgttc ttttacaggg ggttcatttt
    36901 ttcagcaagc acatcaaatt gggatggcag ggttcgaacc tacaattgct tgattcagag
    36961 tcaagtgcct taccagtttg gctacatccc atttattcaa caaaataatc atagcacttt
    37021 cctaaaaaaa cgcaagttat ttttcttgat cggatagttg ttgctttact cgtaaaaggc
    37081 ggcgtactag tttcttttct aatccagcag gaagggcaat cagttctgct actgacaaga
    37141 cggtgtccaa taactgatat tctttgacag gttcattcat aatatgatag atgtttgcta
    37201 aacgttcaat atattcaaag cgagtatact ctgttcgagc aattagaaat ttcaataaat
    37261 cggtggcttt ctcgtactct tgatctgcgt aataaacaag agattgacga tacaatttga
    37321 tttccagttc attgagggta gcaggtctgc gacgctcgtt ccactcatta atagagactt
    37381 taccttgaac atttcccttg cagtcacgga caaaaataat cggaatttca tttggatcca
    37441 tttttttatg tgtgaatttt tccattatct acgctccctt caaaggtttg gtatcttgag
    37501 tataagggat ttttgtttga attactagct tttctccaaa gttagcatct gtccacccat
    37561 tgcagtgaaa atcgccgaaa aatcgttgat cggtactgct cgatttttta caccataggg
    37621 atcgttgaca taaatatttt ctttgtcata tccagtgact acacaagcat gaacaagagg
    37681 agtgactctt acttctccat tatttgtggt ccaagtcata aaatcagttt catctgggac
    37741 ttcaaaattg atagtcacag aagtccagac aggatttcct ttagatagtg cttttttgat
    37801 atcatcgagt tgagcatcgg tttttggaaa agtgtgataa tccgtttgga cgatttgctg
    37861 agcaagggag gcaactgggg gaacatagac gaccatagcc cagtctccgc cactgatatc
    37921 accaacaaat ccttcattag gatcgccatg agtcccatct gcattgaaaa cagggacgta
    37981 atccaattgc tcagctaact ggtttttagt tgtttcataa ccataaaaag ataaaagcat
    38041 agaaagcgaa gtgacttcac agccattttc taaagaagga gaatcaaact ggctctctaa
    38101 tggaacatct agtaaaactt ctgctttctc ttttgtcttt ttcgtttttt gtgttgaact
    38161 tttttgtgca gtgttcattg tatgttctgg agaatggata tgtaggtaat aacttgtacc
    38221 gcttaataaa agagcagctg tgccccctag aaacaatagt tttttgaacg tttttttctt
    38281 catttgaaat ctcccttttc agctgtttat ctttcctatt ataaatgtat ttttattgga
    38341 aatggaagta ttatatttta atatgtagga aataattagt ttttaaggaa tatgttttaa
    38401 ttttttgaaa aaaattcttc taaatacaac agctgtttta attgtgaaaa cgaaaacagt
    38461 acgctataat gcctgtaagg ttgattttta actgtaaata aaaatcaatg agttaaatct
    38521 ccaaagaaat agcagtggta atgtggagaa aagttccagc agtttaggag gattttgatg
    38581 acggaagaaa tgattaattt aggagaacaa tatgcatgca aaccaattgg ttttacaaaa
    38641 acggtcattg gtgaagttgt atcaaaaatg acaaactgcg ccgtggtcaa agttgcccaa
    38701 tgtgctgcag aggaccaaga attattagat gaaaaagcaa gcatggttgt tgcaaaatat
    38761 gatacatttg aataaagaaa acaattggac gtgcggcgtg ctgcaagtcc aatttctttg
    38821 agaaggtaaa tcagtattct tttcctattt tctggagaag aaaaagcgag gcgagttgtc
    38881 atggtaacat tctttacggt tctattgttt ttattcgttg ttgtgatgtt tttatttctt
    38941 tggctggttc gaaaagaaat tatttatcgg actgtgcgaa atcgatgggt ctacttggtg
    39001 atacccttct tagtgtcact agtcatttgg tatacactca tcagtcatcc tacagcagat
    39061 gaattggcaa aagggatctt gtcagcaatg atttttatta gttttttgtt ggacagtaga
    39121 ggaatcacag aagaaggact tgttttgaat agctttgaca aaaaaggtgt tcctttttct
    39181 gagatcaata aaattgtatt atatcagcca aaaggttcta aaatcgtaaa aatgaatttt
    39241 ttccgaaacg gatggcgagg accgatgctg aaattttctg catcattaga agaattagtt
    39301 ccatttttgt cccaacgctt aaacgatgag gcagagattg atattatgat tgatccagaa
    39361 taaaaacaga ggttgcgaca agatgtttgt cacaacctct gttttttatt tcaaataaaa
    39421 ttatccaaat acgcggaagc gatcggcatc gttcatgtat tctttttccc cagccggtgt
    39481 ttctggtgaa ccgaatacta attgcgaacg tagtttccag tttgaaggga tattccattc
    39541 ttttgcaact gcttcgtcaa taactgggtt gtaatgttgc aagtttgcgc ccaatccttt
    39601 atcaactaat gctacccaag tattagctgt tgcgattccg tttgattgtt ctgaccaatc
    39661 tgggaagttg tctgcatata attcaaattg ttcttgtaga ccttttacca cgtcagtatc
    39721 tttgaagaat aatactgtac cataaccatt tttgaaacca gctaatttgt tttgtgtatt
    39781 tgggaaagct tctgctggag tcaatgggcg aagtgcttct tcagtgattt cccaaagttt
    39841 ttcatgtgca tctccgaaaa ggataactgc gcgtgttgat tgagcattga aagcagttgg
    39901 gctttcttta attgcttctt tgatcaaagt tgttaattct tcattagaaa gtgaaacatt
    39961 acgtcctaga tgatagattg aacggcggtt tttcaaagtg tcagtaaaag ttgtcataat
    40021 aaaatttctc ctttgatttg cgttttgcat ttttttaatt gattacgaaa tgaagtatag
    40081 caccttacaa aaagtaagta aacagatatg ctcacaaaaa ataagcgaag ttcaaaaaac
    40141 aattttaata agaaaaatcg ttatgtaagg attttcttag ttatcgcttt cattgttgtg
    40201 ttttaggaat ttttgcttat ttgaaaaaaa cagctgatat ataattatta aatctctatc
    40261 ttcttttttt tatgatattg ccattaaaaa ttacttgctt ttatagaaaa ttagtttata
    40321 tttcttaaat aagtttttta gttaaatttt tcggtaaaga tgtataatat tttctgaaaa
    40381 tttaaagaat tggggtatag attatggaaa aacagcaaga caagggcttc ttcgggcagc
    40441 cgaagggatt gtcaactttg ttcttcactg agatgtggga acgatttagt tattacggta
    40501 tgcgtgcatt acttatctat tatatgtacg atacagttgc caacggggga cttggattac
    40561 cacgagcaac agcattagct atcatgtcga tctacggatc tttgatctac atgtctagta
    40621 tcgtcggcgg atgggtatct gaccgagtgt taggagcaaa acgcactgta ttcttcggtg
    40681 gagttttcat tatgcttggc cacatcgtct tggctttacc atttggtgta agtacattgt
    40741 ttgtttcgat ggcattgatt attatcggaa ccgccttttt gaaaccaaat gtttctggca
    40801 tggtcggaca tctttattca aagactgact tgcgaagaga tgcaggattt tcgatttttt
    40861 acatgggtgt caacttaggg gcattattag caccactaat cgttggtaca atcggtcaag
    40921 aatataacta tcatttaggg ttctctttag ctgctattgg gatgttcttt ggattattac
    40981 aatacatcat ccaaggacgc aagacattag acggagtggg tacaacaccg ccgaatcctt
    41041 tgacaactga agaacgtaaa ggattcatcc gtaacttgat catcgcactt gttgttatcg
    41101 ctgcagtatt cggcggggca caactaactg gtcatctgac aattgacttt tttgtcaata
    41161 caatcagtgt attggggatt atcttaccgt tgtattactt tatcaaaatg ctgacttcaa
    41221 aagatgtaac tgctgaagaa aaaccaagag tatgggctta tatcccatta ttccttgcag
    41281 caatcatttt ctggtcatta caagaacaag gttcatctat cttagcttta tttgctagtg
    41341 aacgtacaca atctacgcta tttggtgtaa cgatccaagc aagctggtat caatcattga
    41401 atccaatttt catctttatt ctgacaccag tattcgtaac gatgtggacg aaacttggtg
    41461 aacgtcaacc atctacagta gtgaaattct ctcttggact tttatttgca ggattatcgt
    41521 acttgctatt gatgttgccg ggtatgcttt atggtacaag tggaaaagta agtccattgt
    41581 ggttgttggg aagtttcttc atcgtggtta ttgctgaatt gtgtctttca ccagttggtt
    41641 tgtctgtgac aacaaaatta gcaccacgag catttgaatc acaaacaatc gctatttggt
    41701 tcttagctga tgcttcttca caagcaatca atgcacaaat tgcacgcttc tacacaccgg
    41761 gaacagaatc tgcttacttc ggtattatcg gtgcagtagc aatcgtcggt ggtatcttgc
    41821 tatttactgt gaaagaacca atcaaaaaac taatgggctc tattcattaa tcaatgaaca
    41881 taaaaacagg aattgcttat ttgcagcagt tcctgtt
//
LOCUS       DAFELK010000020        40814 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFELK010000020
VERSION     DAFELK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.021"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            23..646
                     /locus_tag="LP433_001302"
     CDS             23..646
                     /locus_tag="LP433_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005475.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="LP433_001303"
     CDS             1096..2145
                     /locus_tag="LP433_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2005476.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="LP433_001304"
     CDS             2142..3023
                     /locus_tag="LP433_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2005477.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="LP433_001305"
     CDS             3026..3796
                     /locus_tag="LP433_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2005478.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="LP433_001306"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="LP433_001306"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBL2005479.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="LP433_001307"
     CDS             5107..6270
                     /locus_tag="LP433_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2005480.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="LP433_001308"
     CDS             6387..6797
                     /locus_tag="LP433_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2005481.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="LP433_001309"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="LP433_001309"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL2005482.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="LP433_001310"
     CDS             9370..9654
                     /locus_tag="LP433_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005483.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="LP433_001311"
     CDS             9814..10050
                     /locus_tag="LP433_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2005484.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10403
                     /locus_tag="LP433_001312"
     CDS             10047..10403
                     /locus_tag="LP433_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBL2005485.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSL"
     gene            complement(11112..12056)
                     /locus_tag="LP433_001313"
     CDS             complement(11112..12056)
                     /locus_tag="LP433_001313"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL2005486.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="LP433_001314"
     CDS             complement(12352..13296)
                     /locus_tag="LP433_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005487.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="LP433_001315"
     CDS             13517..14731
                     /locus_tag="LP433_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2005488.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="LP433_001316"
     CDS             14753..16768
                     /locus_tag="LP433_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBL2005489.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="LP433_001317"
     CDS             complement(16851..18224)
                     /locus_tag="LP433_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL2005490.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="LP433_001318"
     CDS             complement(18250..18534)
                     /locus_tag="LP433_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2005491.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="LP433_001319"
     CDS             complement(18536..20551)
                     /locus_tag="LP433_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2005492.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="LP433_001320"
     CDS             complement(20730..21035)
                     /locus_tag="LP433_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBL2005493.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="LP433_001321"
     CDS             complement(21124..22155)
                     /locus_tag="LP433_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2005494.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="LP433_001322"
     CDS             22362..23237
                     /locus_tag="LP433_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2005495.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="LP433_001323"
     CDS             complement(23389..24231)
                     /locus_tag="LP433_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2005496.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="LP433_001324"
     CDS             complement(24323..26200)
                     /locus_tag="LP433_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2005497.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="LP433_001325"
     CDS             complement(26197..27618)
                     /locus_tag="LP433_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2005498.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="LP433_001326"
     CDS             complement(27621..31010)
                     /locus_tag="LP433_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL2005499.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31267..32658
                     /locus_tag="LP433_001327"
     CDS             31267..32658
                     /locus_tag="LP433_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005500.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="LP433_001328"
     CDS             complement(32731..33378)
                     /locus_tag="LP433_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL2005501.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="LP433_001329"
     CDS             complement(33386..34072)
                     /locus_tag="LP433_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005502.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="LP433_001330"
     CDS             complement(34078..35151)
                     /locus_tag="LP433_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2005503.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="LP433_001331"
     CDS             35373..36047
                     /locus_tag="LP433_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2005504.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="LP433_001332"
     CDS             36052..37392
                     /locus_tag="LP433_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2005505.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37541..38527)
                     /locus_tag="LP433_001333"
     CDS             complement(37541..38527)
                     /locus_tag="LP433_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBL2005506.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39251..40282
                     /locus_tag="LP433_001334"
     CDS             39251..40282
                     /locus_tag="LP433_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2005507.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40391..>40814
                     /locus_tag="LP433_001335"
     CDS             40391..>40814
                     /locus_tag="LP433_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL2005508.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT        12668 a         7413 c         7662 g        13071 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta tagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactagat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca tttgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa ttcggatcaa
    24961 ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg tcgatttctt
    25021 tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca aatgttaaag
    25081 cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt ccttctttat
    25141 cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca tttttgatgg
    25261 tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt gtttgctttt
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacttcta
    25381 aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag atccttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt atttgttgta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga atgaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagac tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagggaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt
    37441 ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct
    37501 ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt
    37561 cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg
    37621 tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg
    37681 tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca
    37741 atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt
    37801 cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt
    37861 cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa
    37921 ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg
    37981 tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg
    38041 ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt
    38101 ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt
    38161 ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat
    38221 ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat
    38281 caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc
    38341 gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg
    38401 cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt
    38461 caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct
    38521 cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat
    38581 ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa
    38641 tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt
    38701 tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg tgatggttta
    38761 atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata
    38821 attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat
    38881 acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga
    38941 gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg
    39001 ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag
    39061 gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc
    39121 ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac
    39181 aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag
    39241 ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac
    39301 acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt
    39361 aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt
    39421 attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa
    39481 tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac
    39541 ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca
    39601 ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac
    39661 aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga
    39721 ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga
    39781 agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa
    39841 gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa
    39901 tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt
    39961 tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg
    40021 ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac
    40081 agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact
    40141 atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca
    40201 ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt
    40261 cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt
    40321 attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa
    40381 tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca
    40441 agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt
    40501 cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc
    40561 ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc
    40621 cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat
    40681 gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc
    40741 tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa
    40801 atcaaaacag attc
//
LOCUS       DAFELK010000021        39234 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFELK010000021
VERSION     DAFELK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.022"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(61..1440)
                     /gene="brnQ"
                     /locus_tag="LP433_001336"
     CDS             complement(61..1440)
                     /gene="brnQ"
                     /locus_tag="LP433_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL2005509.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            2146..3117
                     /locus_tag="LP433_001337"
     CDS             2146..3117
                     /locus_tag="LP433_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBL2005510.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            3141..5333
                     /locus_tag="LP433_001338"
     CDS             3141..5333
                     /locus_tag="LP433_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBL2005511.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEVQEE"
     gene            5350..5826
                     /gene="ybeY"
                     /locus_tag="LP433_001339"
     CDS             5350..5826
                     /gene="ybeY"
                     /locus_tag="LP433_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBL2005512.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            5810..6205
                     /locus_tag="LP433_001340"
     CDS             5810..6205
                     /locus_tag="LP433_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBL2005513.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            6220..7119
                     /gene="era"
                     /locus_tag="LP433_001341"
     CDS             6220..7119
                     /gene="era"
                     /locus_tag="LP433_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBL2005514.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            7262..8074
                     /gene="recO"
                     /locus_tag="LP433_001342"
     CDS             7262..8074
                     /gene="recO"
                     /locus_tag="LP433_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBL2005515.1"
                     /translation="MSQLVESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            8458..9375
                     /gene="glyQ"
                     /locus_tag="LP433_001343"
     CDS             8458..9375
                     /gene="glyQ"
                     /locus_tag="LP433_001343"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBL2005516.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            9377..11452
                     /locus_tag="LP433_001344"
     CDS             9377..11452
                     /locus_tag="LP433_001344"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBL2005517.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRVSRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQITAMALSL
                     ASLDQIITK"
     gene            11836..12615
                     /locus_tag="LP433_001345"
     CDS             11836..12615
                     /locus_tag="LP433_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005518.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
     gene            12656..13600
                     /locus_tag="LP433_001346"
     CDS             12656..13600
                     /locus_tag="LP433_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2005519.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            13616..14395
                     /locus_tag="LP433_001347"
     CDS             13616..14395
                     /locus_tag="LP433_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBL2005520.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPTQPKATNDKTAPSRRSRSRV"
     gene            14408..15106
                     /locus_tag="LP433_001348"
     CDS             14408..15106
                     /locus_tag="LP433_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBL2005521.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            15134..15898
                     /locus_tag="LP433_001349"
     CDS             15134..15898
                     /locus_tag="LP433_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBL2005522.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYKQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEIKKKKFGLF"
     gene            15911..17728
                     /locus_tag="LP433_001350"
     CDS             15911..17728
                     /locus_tag="LP433_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2005523.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISTGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASDVSSILILLFINRQYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIQVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESAHVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAKGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNK"
     gene            17742..18965
                     /locus_tag="LP433_001351"
     CDS             17742..18965
                     /locus_tag="LP433_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBL2005524.1"
                     /translation="MNKLEKRQIPFSPPDITDLEIKNVVEVLKSGWITTGPKTKKLEK
                     KITKWLGTSKVVCLNSQTAAAETGLRLLGIGENDEVIVPAYTYSASASVVCHIGANLV
                     LIDCQQDSLEMDYDALEAAITEKTKVIIPVDLGGIPCDYDRIFEIVEKKRNLFQPSNE
                     IQKAYGRIIVMADSAHAFGANWHDQMVGNVADLTTFSFHAVKNFTTAEGGALVWKEHD
                     KLDNEAMYHQCQLLSLHGQSKDALTKTQLGAWEYDIVGPWYKCNMTDVTASIGLAQFE
                     RYPNILKRRKNIIKRYDEAFQQLGIEVLMHYTDDYSSSGHLYITRVPNISSEQRNEII
                     IKMAEQGIACNVHYKPLPMFTAYKNMGFDINNYPNAYAHFVNEITLPLHTKLTDEEVE
                     YVINNYSKIVKDLVG"
     gene            18979..19713
                     /locus_tag="LP433_001352"
     CDS             18979..19713
                     /locus_tag="LP433_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL2005525.1"
                     /translation="MRKWEDLPKEMQNDEIRYYYDILSKKKFSLVVKRVFDILVSATL
                     LLTLSWLFFILAIVIKIDSPGPVFYRQERITRYGKKFKIYKFRTMVINADKDGTLVTV
                     KNDDRITRVGKVIRKYRLDEISQLINVLVGDMSFVGTRPEVGKYVKSYSPLMLATLLL
                     PAGITSETSILYKDEDKLLHDKNNIDKTYIEKILPSKMYYNLKSISEFSCMNDLKIMC
                     KTIFVIFGKEYHADLEGEREFINQIK"
     gene            19730..20341
                     /locus_tag="LP433_001353"
     CDS             19730..20341
                     /locus_tag="LP433_001353"
                     /inference="COORDINATES: protein motif:HMM:NF012792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2005526.1"
                     /translation="MVIEEIKSSDKELINSIVDIHMRTFTNFFLTFMGKKFLELMYRS
                     YTEYNDSGILVAIQNDKPIGFLAYSGDMSGLYKYMIKKRIIPFGFYSCVAFIKKPNIL
                     MRLFRAFLKPSETKRDENYVELASIGVNPKEKSIGVGSMLIDNLKSRIDFSKYEYIAL
                     ETDALNNDVVNNFYKKNEFILERKYSTNEGRIMNEYRFYMEKN"
     gene            20344..21489
                     /locus_tag="LP433_001354"
     CDS             20344..21489
                     /locus_tag="LP433_001354"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2005527.1"
                     /translation="MKLLYILNVANKVNNFSKASMMAAKQTGLEFYIAGNWKYKSDEE
                     RKADEVKYGIKIYQVDFYRNPLNLKNIKAYHQIVEIIKNEKIDIIHCNTPIGGVVGRI
                     AGLKCKVKKVIYQAHGFHFYSGAPKINWFIYYPMERWLAHYTDVLITINHEDYTLAQK
                     LRLRKGGKAYYIPGVGIDTNRFMSSTSIRNFRESICKELNIPDTAKIILSVGELNENK
                     NHLSVIHALQKIPLHTDIYYIIAGVGEMRETLQNIANELGLHQRVFLLGYRSDIPKLL
                     AAANIYILPSLREGLNASLMEAMASGLPCIVGNIRGNVDLIEDGKGGFLINPKDEEEI
                     AGAINRLADNKLLCESMGAHNLDKIKDFDLSVVINQINNVYHEIVSK"
     gene            21512..22564
                     /locus_tag="LP433_001355"
     CDS             21512..22564
                     /locus_tag="LP433_001355"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2005528.1"
                     /translation="MKKIKIMHLLQSNRFSGAENIVCQIMSLFQNNEKFEMIYVSPDG
                     PIANILNIRGLSYLPLKKFSRKEIDRAVHELNPDIIHAHDFNASVRASRYKKQIILSH
                     LHNNPLWLPKLDIRTIIYSLCSSRFNSVIGVSNSVKEEFRYKQLIKDKFVLLPNTVNT
                     ERIIKMGNEFVEDDIDILYVGRMAEPKNPIGAINVLENVVKKYSKHLRVVMIGEGPLF
                     DEVKMQIQKRNLTDVIELKGFKSNPYKYMKKSKVLLMPSLWEGFGLVSVEAMLLETPV
                     VAYNVGGLKDIIDETNGFLCGSEVELSNSLMKLLNSEELRKKMGENAAISAKKFSNMN
                     RYQGVLEKIYVSAALK"
     gene            23093..23869
                     /locus_tag="LP433_001356"
     CDS             23093..23869
                     /locus_tag="LP433_001356"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBL2005529.1"
                     /translation="MAFQVYLQRVYILSTGVIIGHYAEMGLNRIAYAGLMGDFSFAGL
                     YLATGCLYAFLKYVDLKNWKLLFFIIIEVFLLGAILCVSARTGLVSLFVTMTLYYLFN
                     INRISVPHLLVLIGGIITTPYILVMLMAGRSGQSLLDSSGRLENYMSSLNAFSDKYLI
                     GYGLGLNNLYTLLGVAVPHNFFIQYLLQTGIIGTLIILSGFFKFTYEELKKSGCYKWL
                     FLMIVVGAMFIPDIVSSRFLYAIVVLCMISASERTIKKES"
     gene            23880..24341
                     /locus_tag="LP433_001357"
     CDS             23880..24341
                     /locus_tag="LP433_001357"
                     /inference="COORDINATES: protein motif:HMM:NF012360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HBL2005530.1"
                     /translation="MRRKAEKWADKACRQYRNGQNKMSKISCYILRIIYGCEFYGQVD
                     FSSNAQLVHNGLGCVFHPKTKIGNNCKIYQNVTLGGNGKIINGKETVGAPTLEENVAV
                     FAGACVLGPINIGHDSIIGANAVVTKSVPPYSLVYGNPAIITELKFDYKFD"
     gene            24400..25857
                     /locus_tag="LP433_001358"
     CDS             24400..25857
                     /locus_tag="LP433_001358"
                     /inference="COORDINATES: protein motif:HMM:NF024832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HBL2005531.1"
                     /translation="MGNNIHGKTAKALKWSSLAEIIAKIITPISNMILARLLTPDAFG
                     VVATVTMVISFADMFSDSGFQKFLVQHEFDNEEHMFSSTNVAFTSNLGISLLLWLFIC
                     VFNNKIAHLVGNSGLGLVIIVAGVSLPITSFSSIQSAIFRRNFDYKILCYARIISALI
                     PLVITVPLAIIGLSYWSLVIGSIIGNLVTAAILTKLSEWKPKLFFSKKEFYEMFSFSA
                     WSLVESLGTWLSSYIGTFIVGGILSVYYLGIYKTTMTTVNGIFAIVTSATTTVLFSTL
                     SRLQNSKTEYDKTYLDFIKIVSIFIIPLGIGIYVYRELVTNILLGSQWKEAVPFVGIY
                     GLMSCFTLVLGQYASEYYRGLGKPKANVLMTILHLAVLIPVLIIYSRKGFIELAYGRS
                     FVKIEQIIVFWIILWFGFKFNPFKILKQVWKSCASALLMGVLAKIMLEFCTNYVMQLL
                     SVCLCVILYFFIYSCIFKGKTEIINMVRMFTGKGY"
     gene            25892..27061
                     /locus_tag="LP433_001359"
     CDS             25892..27061
                     /locus_tag="LP433_001359"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2005532.1"
                     /translation="MKKVTILIPGMYYGGMERVAFITRQILLKNNYNVSFVTLFDNDA
                     DYQPNFEYLSLKCDIKPSKFGKVINIFKRVYKMKSVKKKLKTDITISFGQSCNLVNVL
                     SKRDDKVYVGIRSYDWLFQYIFHYYVDKFVYKKADAVVSVSQLIKRDAENIFNFNKDK
                     SYFLYNPYDLELINNKSKEKITEIEVPTDKKIIVTVGRLEDQKGLYHLIKAISMLKNK
                     DNVVVYILGHGTKKELLENLIKAYQLQNVIFLLGGQSNPYKYMSRADLYVMPSITEGF
                     PNALVEAMSTETAVLCADCKSGPREILSNRTLDTICENIEYAESGILVCPMTDSRNYS
                     PQYEECDKNLANAIEELIENDNLRNKYAKAAKKRAELYSYDAFEHNLLQIMKTFN"
     gene            27099..28190
                     /locus_tag="LP433_001360"
     CDS             27099..28190
                     /locus_tag="LP433_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBL2005533.1"
                     /translation="MLKKNTSLQNKTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFLFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
     gene            complement(28258..29736)
                     /locus_tag="LP433_001361"
     CDS             complement(28258..29736)
                     /locus_tag="LP433_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBL2005534.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRVESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(30002..30750)
                     /locus_tag="LP433_001362"
                     /pseudo
     CDS             complement(30002..30750)
                     /locus_tag="LP433_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            30893..31843
                     /gene="pfkB"
                     /locus_tag="LP433_001363"
     CDS             30893..31843
                     /gene="pfkB"
                     /locus_tag="LP433_001363"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBL2005535.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQKKQIQTEFIEVPGMTRINVFTQVNQTREE
                     YKLVNQGPEIPQAAVHNFLNQIRALQAEDYLCVSGSLPRGMSPKVLVEISRICQEKEI
                     HLIIDSSDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENV
                     LLSLGEKGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLVGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            31825..33288
                     /locus_tag="LP433_001364"
     CDS             31825..33288
                     /locus_tag="LP433_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2005536.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTILADNEAVDTLESETISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMLKTVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     SGGTGFLVGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVVFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPINKAAYVTGTALLAQGN
                     TTFMAGVSVACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEEGRAGGLS"
     gene            33285..33743
                     /locus_tag="LP433_001365"
     CDS             33285..33743
                     /locus_tag="LP433_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2005537.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKEVYRK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            33740..34714
                     /gene="lacD"
                     /locus_tag="LP433_001366"
     CDS             33740..34714
                     /gene="lacD"
                     /locus_tag="LP433_001366"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL2005538.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPECGLPAAALREKECGLLLAYEKTGYDTKMPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECDAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLKETATPVYVDR"
     gene            complement(34893..35843)
                     /gene="yidC"
                     /locus_tag="LP433_001367"
     CDS             complement(34893..35843)
                     /gene="yidC"
                     /locus_tag="LP433_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL2005539.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(36281..36556)
                     /locus_tag="LP433_001368"
     CDS             complement(36281..36556)
                     /locus_tag="LP433_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBL2005540.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            36664..37428
                     /locus_tag="LP433_001369"
     CDS             36664..37428
                     /locus_tag="LP433_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBL2005541.1"
                     /translation="MKEIQSAKNPKIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            37551..38054
                     /locus_tag="LP433_001370"
     CDS             37551..38054
                     /locus_tag="LP433_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2005542.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            38462..39109
                     /locus_tag="LP433_001371"
     CDS             38462..39109
                     /locus_tag="LP433_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBL2005543.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALATEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMIYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
BASE COUNT        13239 a         6412 c         7932 g        11651 t
ORIGIN      
        1 tttcttctag ctgttttttt cctgtttaat atctcttatg ttaaattgtg tttgatttgg
       61 ttattcttct ggtaactcac ttgcttcttg tttatatcct gatacgcgat atacataata
      121 aaagagcaag ctgccagcgt aaccaagcaa tgttgggacg acccagccaa gacctaatgc
      181 agcaaaagga acataatgat gataaaatcc tagtaagctt gctacgacag tttgctgact
      241 cactaatgca ggcgaatttg ccaacatatc caatacggct ggaacggcag aaaagaacat
      301 cgttacttga tagacaaatg gactcttttg gaagaatttt gctgttaagg aaagtaagat
      361 taacgcaagt gacaatggat acaaaagcat caatactggt aaagaccatt ggatgatatt
      421 atccaatccg gcattcgcaa cgacaaaaga gacaaaagtc gttaaccgca gccatgtcat
      481 ataactgact ttagggaaca gtttatggaa atcttgtgca aaagaaacaa cgagtcccat
      541 agcagtagtg aagacaccta atgtgaccat tacccctaag aagctagcac cgaagttacc
      601 taaataaaaa ttagtgatct gagaaagtgc agttccgcca ttttctgata aagacatctt
      661 attcaaactc atcgcaccga gaaggaccag accaaaataa atcatgactt ctaacgcaac
      721 gctcaggcta ccagcttttg ctgttaattc tgtgactttt ttatctttaa aaccaagatc
      781 acgaactgca tggacaaaag tgacacttaa agcaagtaaa gctactgcat caaccgtgtt
      841 gtatccttct aaaacgccat ttgtcaaagc gttcgtctga taagaatctg cagcagattg
      901 gtttagattc cccatgggtt ggaataaaga aacgacaaaa atgatagcta ataatgcaag
      961 aaacaaggag tttaaatact ttccgacata tttgaccaaa cgtgttggat gtacagtaag
     1021 gaaataagca agtaaaaaga aaagagcaga gaataaaaac atacctaatg aatcatattt
     1081 ttcaggcaaa aagggtttag cagccatttc aaaagcagtt gctgctgtcc gcggtgtacc
     1141 aaagaatggt ccgatcgtta aatgaacaag gatcaagaac aaggcagcat accattttcc
     1201 gacaggttta gctaagtcat acagaccatc actttttgtc actactacag ctaagatagc
     1261 taataatggg aaaagagcgc ctgagatggc aaatcctaca ccagcgctga tccagtttga
     1321 tccagccatt tgacctaagt gtacaggaaa gatcagatta cctgacccga agaacatccc
     1381 gaagataagt gaactgacca tcaataattg cttccatgaa taagtttttg tttcttccat
     1441 aaatttttcc tccaataatt atcattttga gtaacaaaat aaacgttgca gaaactagaa
     1501 ataccactaa tatcagattc catgaaaacc accaccttaa aatataaaaa aagccctttt
     1561 ccacttggga aaagggctct agattctaga acggtaccac cttttttcgc ttaaaaaagc
     1621 ttcttcattc acggacgctt ttcgataaag ttatccgcta gcctgataat ggaggcagcc
     1681 acaatgatct acgttttcga cattgactcg gaaatgatgt tcgtctattc gatttattgt
     1741 catttctcac ttacatgact cactgggaat aaatcactga atagcctact gttttcctcg
     1801 acgctttgct gtatatttat ttgttgacgt tataatacac ctgttttttt tgaaatgcaa
     1861 gaatatttca aatattttgt tttctttttt tgaaacaaga aaaataccca gagaatactt
     1921 gctaagttag acggaatact tgtcctctat cttatgcata gcttacatga tcagcttttt
     1981 ttattcaaac gagaccttta gagaatggaa gcggctagtt ttttaacgtt tcttggtact
     2041 tatggttaag caactctttt agaacctttt cttatttgct atatagtttc ttctgagtat
     2101 ggtaaaatag gaaagaatta atcgaaaaaa aggggatgtc tatttttgac ggaagagtct
     2161 agttctttag agattagatt gacggctgct gatgatgtca gcatgctttt aggtgcacac
     2221 gacaagcata taaaactgat tgaggaaaca acggaaacaa ccatccatac acgtggagaa
     2281 atcattcaga tcattggtga gcaatcccag atttccttgg ctgcctcagt cattcggaca
     2341 ttacaggaat tgatcaaacg aggaatccac gtaagtacgc ccgatgttgt gacggcattg
     2401 aaaatggggc aaaaaggtac attagattat tttgttgaga tgtatgagga agagatcgtc
     2461 aaagaccgta atggaaaacc tatacgggta aaaaacagcg gccaaaagaa atatgtcgaa
     2521 tcggtagcca aacatgatat cgtatttggc gtaggaccag ccgggacagg aaaaactttt
     2581 cttgcagtag tattagcaat cgctgccttg aaaaaaggtg aagtgcaaaa aatcattttg
     2641 acgcggcctg ctgtggaagc aggtgaaaat ctaggctttc ttcccgggga tctaaaagaa
     2701 aaagtggatc cttatctgcg gcctgtttat gatgctttat accaaatttt tggattggat
     2761 catacgaacc gattgatgga acgaggcgta atcgaaatcg cacctttagc ttacatgcgg
     2821 gggcgaacat tggatgatgc attcgttatc ttggacgaag cacaaaacac gacagtcgct
     2881 cagatgaaaa tgttcttgac ccgtctcggt tatcaatcaa aaatgattgt caatggggat
     2941 acaagtcaga tagacttgcc tcgagggacg acaagtggtc ttgttcatgc agaacgaaca
     3001 ttaaagcaaa tcaagaaaat cgattttgtt aattttgaag caagtgacgt tgttcggcac
     3061 cctgtagttg ccgaaatcat caaagcttat gaaaaggcag atctccatca agaataagct
     3121 ttgcttagga ggataagcac atgttgaata aaacactgca gaaactacaa gaaaaacttg
     3181 gaaaggcagc attgcctttc ctgctgttct tgttttttat cattatctgc ggcgttacat
     3241 ttagtagtgt caaacaaaag gccaatgatt tcagagaagg ccaagtagca gaagaaagta
     3301 tccgtgcgaa caaaacgatc gagaacacgg aagaaaccga acaaaaaaga aaactggcag
     3361 cagaagcagt cactccagaa tacacttacc aaaaagatct tgcagatgac cagaacaatc
     3421 ggatcaagca actatttgaa ttgatcgata agacgaatga tgccatcaac aaatcttatg
     3481 acgaaaagat tgataaggca aaggaagatg aaaatatccc aaagcctact acagaagagc
     3541 ggatcgccgc gctgaagaaa aattttgaaa atgtgaatgc agaaaatgtt gtgttttatc
     3601 aaaaactacc gaacaatttt tattcgacga tatttgaaat gactgaaact gagattcata
     3661 ctgtgaggga tgagagtctg aagctcattg acgaacagat gagcaaacaa gttcgtgaaa
     3721 gtgaattgga agcttttaaa caagaagcag aagagcaaat ccaatatttg aatgtcacac
     3781 cagcacaaca acaaatgatt cgctacttag tggatcaagg tatcgtagtg aatgacgtat
     3841 tgaatgagaa aaagacagaa gaattgaaac aatccgcacg agaagctgta caaccagtga
     3901 tgatcttcca aggagaaatc attgttcgtg aaggtaatca aatcgatgct tcagctatga
     3961 aaaaattgga attactagga ctgactaatc aaacaacttc gatttttccg ctaattgcca
     4021 tggttttagc tgttttgctt caaatcggcg tactgattta taattcactt caattccaaa
     4081 atgcaggaga aagaacaaaa tacgtgcttt tctatgtgac agctatgtca gtcagcatag
     4141 tgctgatgaa atttttccaa ttattccaaa cggaacaagc tacttatatc ccgctgtttt
     4201 atcccgctgc ttttgcacca cttgttttaa gctttttctt gaatcgaaga gcagggatca
     4261 tggctggtat tttccaagca gtatccgcac ttttcatttt ttatgattcg attggcacga
     4321 actttctaac gattatcttg atgtcttatg ttttctctgg gctcatggca acgattgtca
     4381 gacgcaaacg gatctcagaa caaggattat ctgctgccat gtgggtcatt atttttcctg
     4441 tgatgatgga tgtcattttg atcgtctatc aaggaatgag ctttggtgat gcaacgactt
     4501 ggttaatgct cgtctgcggg ttcactggtg cactcttctc attcttgctg acgatcggtc
     4561 tacacccata tattgaattg atggtcaatg atgacagtgt aattgtatta aatgaactca
     4621 gcaatccaaa tcatccttta ttgaaacagt tgctggaaga agcgccaggt acttatcatc
     4681 atagtatgat ggtagctaat ctaagtgcta acgctgtagc agaaatcggc ggacgttctt
     4741 tgctaactcg agtagcttgc tattatcatg atatcggcaa gatcaaacat gctagctttt
     4801 tcgttgaaaa cttgccttca ggagcggaaa acccgcacaa tttcttattg ccagaagaca
     4861 gtaaacatat tatctttgga catgtgacag atggagccaa aatattggaa gattataata
     4921 tgccgcaaat ggtgatcgat atttgcaaac agcatcatgg aaccacgcta atgcgttatt
     4981 tctacatcaa agcgaaagaa cgcaatccgg aagtaacaga agagcaattc cgttatcctg
     5041 gaccaaaacc gcaaagtcgt gaagcaggga tcgtcaatat tgctgacagt tgtgaggctg
     5101 cagtacgggc aatggatcat ccgacgagcg aaaaaatcga aagttttgtc cataatctta
     5161 tcgaagagcg tatttccgat ggtcaattag acgatagtgg actgaccttg aaagaaatcc
     5221 gaaaagtgga aaaatcatta atcagcggtt taagtagcac cttccattct cggatcaaat
     5281 atcctaaaat gaaaacagaa gttgagaaga taaaggaagt acaagaagaa tagaaagaag
     5341 cgatgtataa tggatattac ctttatggat gaaacaaacc aagtctcaga agagaaaatg
     5401 aaagaaatcg atgacttgct gcaatttgca gcatcttatt taaagctgcc agaggaaaca
     5461 gaaatgtctg ttactttcat ggacaatgcg gcaattcaag taatcaatcg tgattaccgt
     5521 ggaaaagatg caccgacaga cgtcatcagt tttgctctgg aagaagaagg cgaagacgaa
     5581 atcccagtga tttttgaaga tggagagaat ccattacctc gtgtactagg agacatcatg
     5641 atctctattg aacgtgctgc tgaacaagca gaagcttacg gccattcata tgatcgggaa
     5701 cttggctttt tagcggtaca tggatttttg catatcaacg ggtatgacca tatgacacca
     5761 gaagatgaga aagaaatgtt tggtttacag aaagagatct tggatgccta tggactcaaa
     5821 agataaaaac gtagagaaaa acaaacattt cctgatgtct gtggaatttg ctgtccaagg
     5881 agtcaaaacc gtttttgagg aagaacgcaa tatgaggaaa catgttgcgt tcggtatcct
     5941 tgctttattt atgggcgtga ttttccagct tgatcggata gagtggttat ggctgctttt
     6001 agctgttttt ctcgtttgga tagtagagat catcaatact gtttttgaaa atgtagtgga
     6061 catgtttacg gattttcatt ttcatccgat tgggaaaaaa atcaaagata tggcagctgg
     6121 agcagtttta gtgaccgctt gttttgctgt catcattggg ttgattttat ttgtccctaa
     6181 aatatatcat ttgttgttta attaaaaagg agaacgtata tgccagaaca taaatcaggg
     6241 tttgtcgcaa tcgtcggccg cccgaatgta ggaaaatcca cattattgaa ccgaatcgtg
     6301 ggtcaaaaaa ttgccattat gagtgacaag gcacagacaa ctagaaataa aatccaagga
     6361 gtatatacta caccagaagc tcagctgatt tttatcgata caccaggaat ccataaacca
     6421 aagcatcgtc taggagattt tatggtagaa gcagcttaca gtgcgttgaa agaagtggat
     6481 gcagtcttat ttatgatcag tgctgatcaa aaacgtggcc ggggagacga ttttattatt
     6541 gaacgtctaa aaaacgtgca ttctcctgtt tatctgatta tcaataaaat cgataagatc
     6601 catccagacg agttgctggg aatcatcgaa gattattcga cgcagatgcc ttttgcacaa
     6661 gtgattccga tctctgctac agaaggaaac aatgtcgaac gcttaatgga tgtattagtc
     6721 agtgaaatgc cagagggccc acaatatttt ccagatgatc aagtgactga tcatcctgaa
     6781 tacttcatcg tttctgaatt gatccgtgag aaagtcttgt ttttaacacg agacgaagtg
     6841 cctcattctg tcgcagtcgt tgttgattcg atgaagcgaa acgagaatga taaaatccat
     6901 atccaggcca cgatcatcgt cgaaagagat agccaaaaag gaatcattat cggcaaaggc
     6961 ggaaaaatgc tgaagcaagt aggaacgaaa gcaagaaagg atatcgaaaa tcttttagga
     7021 gacaaagtat ttctagaact ttgggtcaaa gtccaaaaag actggcgaga caaaaaagtc
     7081 tatctgcaag acttcggcta ccgaaaagac gagtactgat attctggact tcttataggt
     7141 taggtataga aataaactgg ataaaaatcc gtacgttgag aaaaacagcg gaagatcgaa
     7201 acataaataa tctggatcgg cagaatctgc ttttccagat ttatttttta ggagggagaa
     7261 tatgagccag cttgtagaat cgaaaggctt gattttatct agccgtaatt acaaagaaaa
     7321 agataaatta gtcaaaatct ttacggaatc ttctggcaaa atgatgtttt atatcaaagg
     7381 aatccatcgg caaaatcagc cattagctcc ggctttgctc ccctttaccg aagcagtcta
     7441 tatcggtaat tttcgaagtg aaggtttgtc gtttttaagc agtgtcaaag acgtccatgc
     7501 gtttcggaac atccaagaag atatcttttt gagcggttat ggtacgtatt tgctaaatct
     7561 agtagatgca gcaatcgaag atcatcaata tgacccgcat ttattccaat ttacgcaaca
     7621 agctctgcag cggatggacc aaggagatga tgcagaaatc atcacgaata tctttgaagt
     7681 gcaaatactg caacgcttcg gaatcgcgcc aatttggacg cactgtgtcg tatgcgggga
     7741 aacaaaagga aaatttgact attcttccaa atatggcggt gtgatatgcg agaaacactg
     7801 gccaatggac gaacaccgtt atcatgcaga tcctcgcgct gtttatttcg ttcgaatgtt
     7861 ttcggctatt tcttatgata agatcagtgg aatccacttg aaagaagaaa cgaagcaggc
     7921 aatccgtgac ctcattgacc agttgtatga tgaatatgtc ggtattcatc taaaaagcaa
     7981 aaagttcatt gatcaaatga agtcttgggc acacgtatta aagacgccag agaaaaatat
     8041 gcctgaaaaa gagatacctg aaaaagaaga ataaatgaaa gatacaacaa aaaaatcaaa
     8101 actatttgac aaatacaggg acttccgtct attattaacc gtagattaaa tagatcgttc
     8161 actgagagga tctattatac aaaccagaaa actgcaaaat gaatacgtac attgaccaag
     8221 atcagtaaaa aacacgtggt ttagcgagtt cgggagagtg gaagccggac ccaaacgatt
     8281 tttgaagagg cacttgcgag tacgataaat gaagctgccg aatctttatt cggaagtagg
     8341 gtggaaccgc gaaattattc gtccctatgt ctgtaatcag acatagggac tttttgtcgt
     8401 tttctttcct gtattcttat tgacagcaac gcttaaaaat tgaaaggggc aaaacagatg
     8461 agtaaaaaat tgaccgtcca agatatgatt ttaacattac aaaaattttg gtcatcaaac
     8521 ggctgcatgc tgatgcaagc ttatgataca gaaaaaggag caggtacgat gagcccatat
     8581 acattcttac gggcaatcgg accggaacca tggaatgctg cttatgtaga gccatcccgc
     8641 cgaccagctg acgggcgtta tggagaaaac ccaaaccgtt tgtatcagca tcatcaattt
     8701 caagtcgtaa tgaaaccttc acctgaaaat atccaagagc tttatttaga aagcttgcgt
     8761 cttttaggaa ttgatccatt agaacacgat attcgctttg ttgaagacaa ctgggagaac
     8821 ccatcgatgg gttgtgccgg tgtgggctgg gaagtatggc ttgatgggat ggagatcaca
     8881 caattcacgt acttccagca agtcggagga ctaccttgta aaccagttac ttctgagatc
     8941 acttatggac tagaacgtct tgcttcttat atccaagaag ttgaaagtgt ttatgatctg
     9001 gaatgggctg atggcgtgaa atatggtgag atcttcaaac aaccagaata tgaacattct
     9061 aaatattctt ttgaagtaag cgaccaagac ctgctactaa gcaattttga tcgttttgaa
     9121 aaagaagcta aacgctgtat cgatgaaaat cttgttcatc cagcgtatga ttatattttg
     9181 aaatgtagcc atacattcaa tttattagat gctcgcggtg cagtatccgt aacagagcgt
     9241 gcaggttatc tttcccgtat ccgcaacatg gctcgtgctg tagccaaaat ctttgtggca
     9301 gaacgcgaaa aattaggatt ccctttattg aataaaaaca cagcaaatcc agaaaacgtg
     9361 aaggaggctg aataagatgg caaaagactt attacttgaa atcgggctgg aagaaatgcc
     9421 tgctcatgta gtcacaccaa gcatgaaaca attagaagaa aaaacagcaa aatttttaga
     9481 tgaaaaccaa ttgacttatg atacgatcga aacgttttct acaccgcgcc gcttagcaat
     9541 caaagtaaca aacattccag aacgtcaagc agacagcgaa gaagaagtca aaggaccagc
     9601 caaaaaaatt gctttggacg cagatggaaa ctggacgaaa gcagctgaag gatttgtccg
     9661 cggacaaggt ctgacgacag atgctatcac ttttagagaa ttaaaaggcg tggaatatgt
     9721 ctatgtaacg aaatacactc acggcaaaga agcaaaagaa gtattgacag gtttagcaga
     9781 tgtcattaaa agcctcactt tcccagtaac gatgcactgg gcagaatacg attttgaata
     9841 tattcgccct attcactgga tcgtggcatt gttagatgac gaaataatcc cgtttgagat
     9901 cttggatgtc aaaacagaca gagtttcaag aggtcatcgt ttcttaggcg aagatgtgac
     9961 atttacgcat gcaaaagaat acgaagaaaa attgaatgaa caatttgtta ttgcttcacc
    10021 gcaaaaaaga aaagaaatga tcatcacaca agcaaacgaa ttagcagaaa aaaatcactg
    10081 gatcattgat ctagatgaag atttactaga agaagtcaac aatctagtcg aatatccaac
    10141 tgtcttttct ggcgacttcg aagaaaaata tctatctgtt cctgaagaag tactagtcac
    10201 ttctatgaaa gaacatcaac gttatttcga agtacggaac gatcaaggta tgttgcttcc
    10261 tcattttatt tctgctcgta atggcgatcg ggtaaaattg gaaaatgtgg tacgaggcaa
    10321 tcaaaaagta ttgactgctc gtttagaaga tgcggaattc ttttataatg aagacaagaa
    10381 agcttcaatc gaccaatacg ttgaaaaatt aaaaactgtt actttccatg aaaaaatcgg
    10441 tagcatctat gagaaaatgc aacgggtaca agtcatcgct cgcatcatag gcgaacaagt
    10501 aggactatct gaggaagaat tgatggatct gcaacgcgct gctgaaatct ataaatttga
    10561 tctagtaacc aacatggtag gagaattccc tgaactacaa gggatcatgg gagaaaaata
    10621 tgctctgctt aaaggcgaga aaccagccgt agcaacagcg atccgtgaac attacatgcc
    10681 tatatccagt gaaggagatt tacctgagac tacagtaggt tctgttttag cgattgctga
    10741 taaattagat agtatctttt ctttctttgc agttgggatg atcccaagtg gctcaaacga
    10801 tccatatgct ttgcgccgtc aagcatatgg tgtcgttcga atcatcgaat cgaaaaaatg
    10861 ggcctttcct ttgtctgttc tgcaagaaac gattagtgaa gttatcagta aagatacgga
    10921 tcgttttggc attggcttgt cagcgggaca acaacaggtg atcgacttta tcaaaggccg
    10981 tctgcgccaa ttattgacaa cgaagaatat ccgtcatgat gtcatcgaag ctgttttgaa
    11041 tgcagaacaa aaagatctga caaaagtatt tgcagcagca caattgttca aacaacatct
    11101 tgcagatgaa gacttcaaac cttcaatgga agcattgaca cgtgtcgtga acttagcgaa
    11161 aaaagcgcag cttgaaaaac aatcagaagt agaccctgag ctgttcgaaa acgacgcaga
    11221 gaaagaatta cacaaagcag tagaagcaat gaaagcaagt tttgctgacc aaacgatcca
    11281 cgaaaactac gaccagcttg tcgctcttcg tccactgatc gaaaattatt ttgatcaaac
    11341 gatggtcatg gctgatgaac cagcagtacg taagaaccga ctaacacaac ttagtcaaat
    11401 aactgccatg gctttgtcat tagcaagctt ggatcaaatc atcacaaaat agtcttttgt
    11461 ttgaaaaaca gagagcatgc acgaaacgtg ctgtgtctct gtttttttgt tataaatata
    11521 aaagctgtta ttaattctat tttaataatt tttgttattt tattctttgc tagaattttc
    11581 aaaacgctca tgaaaagtga ggaaataaaa atgaaaaaga ttaataataa tcttgttact
    11641 gttttattta cttttaaatt aggaatttcc ctagtcaaga aaactgtttg tggtatgatt
    11701 atatagggaa aacctgttta taaatatttc tatgaatata ttagtttaat tatgctttta
    11761 aaataaaaag cgctcattct gatgtgaatg aatcacatct ttatttatct atcatcaata
    11821 tttaggagtg aatctatgga aaagccgttc gtcaagttat tggctactgt ggcggtaggc
    11881 acaggcgcta ttgtgatttg cttgtttgga taccatctca ataatcagcg gcaacatcat
    11941 caacggatca attacgcaga atctgccatc accaatcaaa aagacaccgt gacctcttta
    12001 tcaaaagaag tagataagct gtacagtaca aaagaaaaaa ttttcctaaa tcctgaaata
    12061 acagaagaaa cagtttcaaa tttgtcacat aaactatctt ctatcaaact ttcagcagat
    12121 gattatgaca tcaaggaatc agaattacct aaagaagctg ctgcgatcca agaagaaaag
    12181 aaagcagtct taacacagtt agaggatgca gaatcaaaac tgaagatcca aacggctgtc
    12241 aataaattat ttactaaaaa cgtatcaaac tggcagcaag ctgtggatga tgtcatcatc
    12301 aaagaaaagt tggcaagtgc agatgtcgcc catgtacgtg aaaatatgag cttttttaag
    12361 gatagtgctt ggaaaacggt cgttatgcaa tatctaggat tcgctgatac ccaaattgca
    12421 caagtcacgc aactagatca gctattcgat acgatgctga aagacggtca agtaacagct
    12481 actgctactt acgatcaata tttgaccgca ctcagtctca tcgaacagat ccggaatgaa
    12541 aaaataagag ccgcatacgc gtcaaaagca gaaacagtcg ctcagcaaat gggctatagc
    12601 aatacgagct attaataagc gagaattcaa gcaaggctag caaacggagg aaactatggc
    12661 aaaacgaaga agaagatcaa gagggaaaaa gatatttcta attattttag caattcttgt
    12721 cgtattagta ttagcaatcg taggagtagg agcaaaatta tatctagatc tctcacattc
    12781 tattgaaaaa acttacgaat cagtggaacg aacccaagga gaacgaacaa aaccagttga
    12841 tctggacaaa caagaatctt tctctgttct attgatgggg attgatacgg gagatttagg
    12901 tcgggtcgat caaggaagat cagatacgat gatggttgcc acagtcagtc ctgaagacaa
    12961 acagacaacg attgtcagca ttcctcgtga tacgtatgtc gacatcgttg gacatgacac
    13021 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
    13081 acaaaaatat gtagacatcc caatcgatca ctatgtttca atcaatatga aaggtctaaa
    13141 agaactcgtt gatgcagttg gtggtatcga agtcaataat gacctcacct tctcacaaga
    13201 tggctatgat tttacgatcg gtaaaatcac attgaacggg gatcaggcat tgtcttattc
    13261 tcgtatgcgt tatgaagatc caaatggtga ctacggcaga caagaacgtc aaagaaagat
    13321 cgtagaaggt gtagcgaaaa aagtgttgag tctgaacggt gtaagcaact atcaatccgt
    13381 tttgaatgct ctagagtcga atatgaaaac agacatgagc tttgatgaaa tgaaaaagat
    13441 tgctttagat tatcgggatg catttggtac gatcaagcaa gatcagctgc aaggagaagg
    13501 cttcatgcaa gacaatatct cataccaaaa agtcagcgat caagaacttg atcgtgtgaa
    13561 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
    13621 agagacaatc agcttgaaag aaatttttga aacattacgc aaacacgtga taacaatcct
    13681 catctcaatg tttgctggct tggccatctc aggcatcgtg acgtttttca tcttgacgcc
    13741 aaaatacagc tcacaagccc aattgatcgt gacactgccg caatcagata ctgcaaatgt
    13801 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaggatatga tcgtcagtga
    13861 tctagtacta aatgaagtca aagatcgttt agaaacagaa gacaatgtaa aaatgactgc
    13921 tggacaaatc aaagatgcca tctccgtcaa tcagtcacaa aattcacaaa tgttctcgat
    13981 ccaagcaaca agcacaaatg cagtgacggc tcaacaaatc gctaatacaa cgtcacaagt
    14041 attccaagag aacgccaaag acgtgatgaa tgtcgataaa atctcgatca tctcaggtgc
    14101 agttgccaat acgacacctg tttcgccaaa taataaattg aatctagtga ttggcttagt
    14161 gttaggaatg atggtaggcg taggtctagc tttcttattt gaattactcg accggacagt
    14221 aaaagatgaa aaatatgtga cggatacatt gggcttcccg atcttaggga ctgtaccaga
    14281 aatgtcagcg aaagaattga atgctggtat ccgtaaaaaa ggaccagctc cgacacaacc
    14341 aaaagctaca aacgataaaa cagcgccatc acgcagaagc cgctcaagag tctaggagga
    14401 aagaaaaatg gcacgaacac agaaacaaaa agcagcccaa actcatgcag tcagtttggt
    14461 cacactcaca aacccctctt caccaatcgc tgaacaatat cgtacgattc ggacgaatat
    14521 ccagtttgcc tccgcagctg gtcagcaaat taaaacgatt gttgtgactt catcaggacc
    14581 tggagaaggg aaatcgacca ctgcagcaaa cattgccgtt gtttttgcca aatctggtca
    14641 acgggtgctg ctagtcgatg cagacttacg taagcccgtc atctataaaa cgttcaagtt
    14701 gaacaacgca agcggattaa gtaccgttct tagttcatca ggaagtgtag cagatgagat
    14761 ccaacgaaca ccagtcgaga atttgtcgat tctgccaagt ggacctaaac caccaaatcc
    14821 atcagaacta ctaagttcgc caagaatgga tcagatttta gcagaagcaa gacaactatt
    14881 tgatgtagtg atcttcgaca tgccgccagt agttgccgta acagatgcac agatcatgtc
    14941 ttccaaaacg gatggcacct tattggtcgt acgtgaaaat atgtcacgga aagaatcatt
    15001 gactaaagca aaagaattgc tggatatggt acaagcgcga gtccttggtg ttgtatacaa
    15061 tggggcagaa cacagcaaag atgctggcta ttactacggg aattaagaaa taaaaagaga
    15121 ggagacaaga gaaatgatcg atctacattg ccatatcctg ccaggaatcg atgacggagc
    15181 agaaaacata gatgccagta tcgccatggc tgaaaaagcg attcaacaag ggatcacaca
    15241 tattttatgc acaccccatc ataataatgg aaaatacagc aatgaaaaat cacaagtcat
    15301 ttctctagtc gcttcgttac aagcagaatt agagaaaaga caattgcctt tgacgttatt
    15361 ggaaggacaa gaagtacgta ttaccggaac actgatcgaa gacatcgacc gagatgaaat
    15421 tttatttaca gatttagatg atacatatct tctaatcgaa tttccgacac tggaagtgcc
    15481 gttatatgca gaacagctct tttttgagtt gttacaacta ggaaagacac cagtgatcgt
    15541 ccatccagaa cgcaacgcgc attttcgtaa agacccgaat catatgctgc cattcctaga
    15601 tatgggatgc ttggcccaac tcaccgcacc aagttatgtc ggtgtatttg gaaaagacat
    15661 ccagaaaaca gccaaaatga tggtcaaaca taatcttgtg cagatggctg cttctgatgc
    15721 ccatggggtc tctaagcgca ccttttactt aaaagagtgc tataagcaga ttgccaagga
    15781 ctttggtaag gaaaaagtag tacagatgaa acaagtcgca aaggatctga tcaacgggga
    15841 tgaaatcagt tatccagtct atgaagagat aaaaaagaag aagtttggtt tattttaggg
    15901 ggagtgtaag gtgtttgtat taacaagaag aagaaaaatt gccacattgg ttgttgtgga
    15961 cagtttgtta ttgatcgctg caaatattgc agcagctaaa ttcatgaagc cgtttgtagc
    16021 tataccaatg gaccttattt taatctctac cggtttgtcg attggttttt atttatttta
    16081 tggtagttta ttcaaagttt tcactcggat caatcgctat acaaatttaa gagagatcat
    16141 tgcaattttt ggttcactat ctgcaagtga cgtctcaagt atcctcatac tgctgttcat
    16201 taatcggcaa tacagtttac ggttagttat ctttgcttat ctgctttcgc tcttattgat
    16261 catcggtagc cgattgatct ggcgtatcta catcgaaaca aaaaatatga gatatgtatc
    16321 agcggattct gctaaaaata cattgatcgt tggtgctggc gaaggcgggc gtattttata
    16381 caacagcttt ctgggatcca aaacggctca agatatccaa gttgtcggat ttgtagatga
    16441 tgatccgaat aaaagaaata cgtatctttc aggaaaaaaa gtattaggtg cattaaaaga
    16501 tattccggaa ttgattgaaa aatatgacat tcaaatggta acgatcgcta tcccttcctt
    16561 atcaagaaaa aaattacgaa gaatcttcga gttagtcgaa tccgctcacg tgaaagtcaa
    16621 cacgatgcct tctatagaag aacttgcttc aggaaaaatt agcgtatcaa aattaaaaac
    16681 aattgacgta gtggatttac tgggaagaga tgaggtaaag ctggatattg aatccatcaa
    16741 agatcagatc acagacaaag tcattcttgt caccggcgca ggaggatcga tcggttcaga
    16801 aatctgtcgg caaatcattc aattcaatcc tgcaaagcta ttgcttttag gacatgggga
    16861 gaactcgatc tacttgattg accgtgagtt acgcacgcat catcaaaatt gtcctacaga
    16921 aatcgtaccg atcatcgcag atatccaaga tcgcgagaaa atcaatgaga tcatggaaca
    16981 atatcatcca gatatcgtct accatgcagc tgctcataaa catgtaccac tgatggaata
    17041 taatccaaaa gaagcagtca aaaacaatat tttcggtaca aaaaatgtag cagaagcagc
    17101 taaagcagca aaagtgaaaa acttcgtcat ggtatcgaca gataaagcta acaatcctcc
    17161 aaatgtcatg ggttcaacaa aacgaatcgc tgaaatgatc gtgactggat tgaatgaaga
    17221 aggctgtacg aaattctcag ctgtcagatt tgggaatgtc cttggttctc gcggtagtgt
    17281 gattccagta ttcagagaac aaattgctaa aggtggtcca atcactgtaa cagactttcg
    17341 tatgacccga tacttcatga cgattcctga agctagtcgt ttagttattc aatctggcgc
    17401 attagcaaaa ggtggcgaaa tttttattct agatatgagt gaaccagtga agattgtaga
    17461 cctagccaaa aacatgatcc gattgagcgg gtatagcgaa gacgaaatcg aaatcattga
    17521 aacaggtatc cgtccagggg aaaaactata tgaagaacta ctgttggata aggaaagaaa
    17581 tgatgaagca gtttatgaga aaatctttgt aggaaacatc aaaggttact caatacaaaa
    17641 agtgatggat tttgtcaaga gcctgccgca agacgatgaa caattggcta aagatatcgt
    17701 cacttttgca aatgcttcga ataaataggg gggaaatata aatgaataaa ttagaaaaac
    17761 gtcagatacc attttcaccg ccagatatta ctgatttaga aataaaaaac gttgtagaag
    17821 tattaaaatc tggatggata actacgggac caaagacaaa aaaattagaa aaaaaaatta
    17881 caaagtggtt aggaacttct aaagtagttt gtttaaattc acaaactgct gctgcagaaa
    17941 cagggttacg tttgctggga ataggagaaa atgatgaggt tatcgtccca gcttatactt
    18001 attctgccag tgcatcggtt gtatgccaca taggcgcgaa cctagtatta atagactgtc
    18061 aacaagattc tttggagatg gattacgatg cattagaagc agcaattacg gagaagacaa
    18121 aagtgattat tcctgttgat cttggtggta taccttgtga ctacgaccgt atttttgaga
    18181 ttgtggagaa aaaaagaaat ttatttcaac ctagtaatga gattcagaaa gcttatggtc
    18241 gtataattgt tatggcagat tctgctcatg catttggagc taattggcat gatcagatgg
    18301 ttggtaatgt tgctgacttg acaacatttt catttcatgc tgttaagaat tttacaactg
    18361 cagaaggtgg agctttagta tggaaagagc acgacaaact agataatgag gcaatgtatc
    18421 atcagtgcca gctgctttct ttgcatggac agtcaaaaga tgcacttact aaaacacagt
    18481 tgggtgcatg ggaatatgat attgtgggtc catggtataa atgtaatatg actgatgtta
    18541 ctgcatcaat tgggttggca caatttgaac gctatcctaa tattctgaaa agaagaaaga
    18601 atataattaa gaggtatgat gaagcctttc aacaactagg aattgaagtt cttatgcatt
    18661 atacggatga ttatagttct tcaggccatt tatatattac tagagtacct aacattagtt
    18721 ctgagcaaag aaatgaaata attataaaaa tggcagaaca agggattgct tgcaacgttc
    18781 actataaacc acttccaatg tttacagcat ataaaaatat ggggtttgat attaataact
    18841 atcctaatgc ctatgctcat tttgtaaatg agattacatt accattgcac acgaaactta
    18901 cagatgaaga agtagaatac gtaattaata actatagtaa gattgtaaag gatttggttg
    18961 gatgatagga gaggcaaaat gagaaagtgg gaagatttgc caaaagaaat gcagaatgat
    19021 gaaatacggt attattatga tatcctcagt aaaaaaaaat tcagcttagt ggtaaaaaga
    19081 gtatttgata ttttagtgtc tgcaactttg ttactgacac tttcatggtt attttttatt
    19141 cttgcaatag tgataaaaat tgattctcct ggacctgtat tttatagaca agaacgtatt
    19201 actcgttatg gaaaaaaatt taaaatttat aagtttcgta ctatggtaat aaatgcagat
    19261 aaagatggca ctcttgttac tgtgaaaaat gatgatcgta ttacaagagt aggaaaggta
    19321 atccgtaaat atagattaga tgaaattagt cagctaatta acgttttggt cggagatatg
    19381 tcttttgtag gaaccagacc agaagttgga aaatatgtaa agtcgtattc accattaatg
    19441 ttagccacat tattattacc agccgggatt acatcagaaa ctagtatttt atacaaagat
    19501 gaagataaat tgttgcatga taaaaataac atcgacaaaa cttatataga aaaaattctt
    19561 cccagtaaaa tgtattacaa tttgaaaagt atcagtgaat ttagttgtat gaatgatttg
    19621 aaaataatgt gtaaaactat ttttgttata tttggtaaag aatatcacgc cgacttagaa
    19681 ggtgaacgag agtttattaa tcagataaaa tgaatggagg ataagagttt tggtgattga
    19741 agagataaaa agttcggata aagagttaat taattcgatt gtcgatattc atatgagaac
    19801 atttacaaat ttttttttga ctttcatggg aaaaaagttt ttggaattga tgtatcgttc
    19861 ttacacagaa tataatgatt ctggtatatt ggttgctatt caaaatgata agccaatagg
    19921 atttcttgca tattctggag atatgagtgg tttatataag tatatgataa agaaaagaat
    19981 aataccgttt ggattttata gttgtgtagc ctttataaag aaacccaata tccttatgag
    20041 gctttttaga gcttttctaa aaccaagcga aacaaaacgt gatgaaaatt atgtggaatt
    20101 agcatccatt ggagttaatc cgaaagagaa atcgatagga gtaggttcca tgcttataga
    20161 taacttaaag agtagaattg atttttcaaa atatgaatat attgcactag aaacagatgc
    20221 attaaataat gatgttgtga ataattttta taaaaagaat gagttcattt tagaacgtaa
    20281 atattctact aatgaaggaa gaattatgaa tgaatatcgg ttttatatgg agaagaatta
    20341 attatgaaat tattgtatat tttaaatgta gctaataaag taaataactt ttctaaagct
    20401 agtatgatgg cagctaaaca aacgggttta gaattttata tagctggtaa ctggaaatac
    20461 aaatccgatg aggaaagaaa agctgatgaa gtgaaatatg gaataaaaat ataccaagtt
    20521 gatttttata gaaacccact aaatttaaaa aatataaaag cttatcatca gattgtagag
    20581 attataaaaa atgaaaaaat agatattatc cattgtaata cacctattgg aggtgttgtc
    20641 ggacggattg ctggtcttaa atgtaaagtc aaaaaagtaa tttaccaggc acatggattt
    20701 catttttatt caggtgctcc taaaataaat tggtttatat attatcctat ggaacgttgg
    20761 ctagctcatt atacagatgt tttgattaca ataaatcatg aggattatac tttagctcaa
    20821 aaacttcgtc ttaggaaagg tggaaaagct tattatattc caggtgtggg tatagataca
    20881 aataggttta tgtcttccac atcaataagg aattttagag aaagtatatg taaagaactt
    20941 aatatacctg atacagcaaa aatcatttta tctgtaggag agctaaatga gaataaaaac
    21001 catttatcag taatacatgc attacaaaaa attccgctgc atacagatat ctattatatt
    21061 atcgctgggg taggagaaat gagggagaca ctacaaaata ttgctaatga attaggatta
    21121 catcagcgag tttttttact aggatataga agtgatatac ccaaattatt agctgctgca
    21181 aacatatata ttctaccctc attaagggaa ggcctcaacg cctctttaat ggaagcgatg
    21241 gctagtggtt taccatgtat tgtcggtaat ataagaggaa atgtagatct tatagaagat
    21301 ggtaagggtg gatttctaat caatcctaaa gacgaagaag aaattgctgg tgcgataaat
    21361 agattggctg ataacaaatt attgtgtgaa tctatggggg cacataattt agacaagata
    21421 aaagattttg atttatcagt tgtgataaac caaataaata atgtttacca tgaaattgta
    21481 agtaaataat tgaattgaaa gtgatattaa tatgaaaaaa ataaaaatta tgcatttgtt
    21541 gcaaagtaat agattttctg gcgctgaaaa tattgtttgt caaataatga gtttatttca
    21601 aaataacgaa aaatttgaga tgatttacgt tagcccagat ggtcctatag caaatatttt
    21661 aaatattaga ggtttaagtt acttaccatt aaaaaaattt tcgagaaaag aaattgacag
    21721 agccgtacat gaattaaacc cagatataat tcatgctcat gattttaatg ctagtgtaag
    21781 agcaagtaga tataagaagc aaatcatcct ttcccatttg cacaataatc ccttgtggtt
    21841 acctaaacta gacataagaa ctattatata ttctttatgt tcgtctaggt ttaattcagt
    21901 aattggtgtt tcgaattccg ttaaggaaga atttcgttac aaacaattaa taaaagataa
    21961 atttgtgttg ttacctaaca ctgtaaatac tgaaagaatt ataaaaatgg ggaatgaatt
    22021 tgttgaagat gatattgata ttttatatgt aggacgcatg gcagaaccta aaaatccaat
    22081 aggtgcaatt aatgttttag aaaatgtagt aaaaaaatat tcaaaacatt tacgtgtcgt
    22141 gatgattggt gaaggaccat tatttgatga agttaagatg caaatacaaa aaagaaactt
    22201 aacagatgtt attgagttaa agggattcaa aagtaatccc tataagtaca tgaagaaatc
    22261 taaagttcta ttaatgccat ctctttggga agggtttggc ctagtatcag tagaggcaat
    22321 gttgttagag acgcctgttg tagcttataa cgtaggagga ttgaaggata ttatcgatga
    22381 gacaaatgga tttctgtgtg gtagtgaagt tgaattatct aattcactaa tgaagctatt
    22441 aaattcagaa gaacttagaa aaaaaatggg agaaaatgct gctattagtg caaagaaatt
    22501 ttctaatatg aatcgttatc aaggagtatt agaaaaaatt tatgtatctg cagctttaaa
    22561 ataaaatatg aattataaaa atagagatca attagtttta cgaaaaataa tacccattag
    22621 tattttgttt caatcaggaa tgatttttta ttcactgatg ccctcaatag caattgcagt
    22681 tgtttctttt tttatgtttt tgtattatat gtggtgctta aaaaagtatt tttgtttagc
    22741 agatagctta ttgttaacat caattctttt cattccaaca tcaactatat ctatattagg
    22801 aactagttat tctagcttac cattgacgtg gcataatcta ataataataa ttttgatgtt
    22861 atatattatt atagaaggaa cattaaatcg ttcatacttg attattttat ttttatttat
    22921 ttgttttgga atatcgacgt ctatgttctt acctttttta atagatgcat taaagcaatt
    22981 aatgactatt tcgttgttta tctgtagttt tttaatagga aaacgtttta aaatgtatag
    23041 caaaaactta actatgattg ggtggaattt ctatttcata ggagtagtat ctatggcgtt
    23101 tcaggtatat ttgcaacgag tatatatttt atctactggt gtaataatag gccattatgc
    23161 agaaatgggt ttaaatagaa ttgcatatgc aggtttgatg ggagatttta gttttgcagg
    23221 gttatatctt gctacaggct gtctatatgc ttttctaaaa tatgtggatt taaaaaattg
    23281 gaaattatta ttctttataa taatagaagt atttttatta ggtgcaattt tatgtgttag
    23341 tgcaagaaca gggttagttt ccttgtttgt cacaatgaca ttgtattatc tatttaatat
    23401 aaatagaatt agtgttcctc atcttttagt tctaataggt ggaatcataa ctacacctta
    23461 tatactagta atgttaatgg caggtcgttc tggacaaagt cttttggatt cttcaggcag
    23521 attagaaaac tatatgtcct ctttaaatgc ttttagtgat aaatacttaa taggatatgg
    23581 attaggatta aataatttat acacgctact aggtgtagca gtaccacata atttttttat
    23641 tcaatattta ttacagacag gaattattgg tacgctaatt attttaagtg gcttctttaa
    23701 atttacgtat gaagaattaa agaaatcagg ttgctataaa tggttatttt tgatgatagt
    23761 agtgggagca atgtttatac cggatattgt atcttcgcgt tttctttacg caatagttgt
    23821 tttgtgtatg atttctgcat cagaaagaac tataaaaaaa gaaagttgag gtagaaaaaa
    23881 tgagaagaaa agcagagaaa tgggcagata aagcttgtag acaatacagg aatggtcaaa
    23941 ataaaatgtc aaaaatatcc tgctatattt taaggattat ttatggatgt gaattctacg
    24001 gacaggtaga ttttagctct aatgctcaac tagtccataa tggtcttggt tgtgtattcc
    24061 accctaaaac aaaaatcggt aataattgta aaatatatca aaatgtgact ttgggtggaa
    24121 atggcaaaat aataaatgga aaagaaactg ttggggcacc aacgctagag gaaaatgtgg
    24181 ctgttttcgc tggtgcatgt gttttaggac caattaatat cggacatgat tcaatcatag
    24241 gtgcaaatgc tgtagttaca aaaagtgttc caccatatag cttagtatat ggaaatccag
    24301 caatcataac agagttgaaa tttgattata aatttgatta aaaagtaatg tttaatatgc
    24361 gaaaggttgc tatatttatt tagcaaaatg gggtaataaa tgggaaataa tattcatgga
    24421 aagacagcaa aagctttaaa atggtcatcc ttagctgaaa taattgcaaa gattataact
    24481 ccaatttcga atatgatttt agctagatta ttgactccag atgcttttgg agtagtagcc
    24541 actgtaacta tggttattag tttcgctgat atgtttagtg attcaggatt tcaaaaattt
    24601 ttagtacagc atgaatttga taatgaagaa cacatgtttt catcaacaaa tgtagctttt
    24661 actagtaact taggtatttc tttattatta tggttattta tttgtgtgtt taataataaa
    24721 atagcgcact tagttggaaa ttctggactt ggattagtaa ttatagtagc tggagtttct
    24781 cttccaatta cttctttttc cagtatacaa tcggcaattt ttagacgaaa ttttgattac
    24841 aaaattttgt gttatgctag aataatatct gcattgatac ctttagttat tacagtaccg
    24901 ttggcgataa ttggactaag ttattggtca ctagtaattg gatctataat aggaaattta
    24961 gttacagctg caatattaac taagttatca gagtggaaac caaaactttt tttttcaaaa
    25021 aaagaatttt acgaaatgtt ttcctttagt gcgtggtcac tagtggaatc attaggtaca
    25081 tggttgtcat cttatatagg tacttttatc gtaggaggca ttttaagcgt atactatttg
    25141 ggaatataca aaactacaat gacaacggtt aatggtattt ttgcaattgt aacttcagca
    25201 acaacaactg tattattttc aacattatct cgtttacaaa atagtaaaac ggagtatgat
    25261 aagacatatt tagattttat taaaattgtt tccattttta ttattcctct gggtataggt
    25321 atatatgtat atagggaact agtaacaaat attctactcg ggagtcaatg gaaagaggct
    25381 gtaccatttg ttgggatata tggattaatg agctgtttta ctcttgtctt gggacaatat
    25441 gcctctgagt actatcgtgg tttaggaaaa ccaaaagcaa atgttcttat gactatccta
    25501 catttagcag tattaattcc agttctaata atctattcaa ggaaagggtt tatagaacta
    25561 gcatatggta gatctttcgt taagatagag cagattatag tcttttggat tattttatgg
    25621 tttggtttta agtttaatcc atttaaaatt ttaaagcagg tttggaaatc ttgtgctagt
    25681 gcattgctaa tgggagttct agcaaaaatt atgttggaat tctgtactaa ttatgttatg
    25741 caattacttt cagtgtgtct ttgtgtaatt ctatattttt ttatatatag ttgtatattt
    25801 aaaggaaaaa cagaaataat taatatggtt agaatgttta ctggtaaagg atattaagag
    25861 agatttttat ggcaaggttg tgattaggaa aatgaaaaaa gtaacaattt taattcctgg
    25921 aatgtattat ggtggaatgg aaagagtagc ttttataacg cgtcaaatac ttttgaaaaa
    25981 taattataat gtatcatttg taactctttt tgataacgat gcagattatc agccaaattt
    26041 tgaatattta tcattaaaat gtgatataaa gccatcaaaa tttggtaaag taattaacat
    26101 ttttaaaaga gtttataaaa tgaaaagtgt caaaaaaaaa ttgaaaacgg atataactat
    26161 atcttttgga caaagttgta atttagtaaa tgttttatca aagagagatg ataaagtata
    26221 tgttggaatc cggtcctatg actggctatt tcaatatata ttccattact atgtagataa
    26281 atttgtatat aagaaagcag atgctgttgt gtctgtcagt cagttaatta aacgtgatgc
    26341 tgaaaatatt ttcaatttta ataaggataa aagctatttt ttatataatc catatgattt
    26401 agagttgata aataataaga gtaaagaaaa aattacagaa atagaggttc caacagacaa
    26461 aaaaattata gtgacggttg gtcgattaga agatcaaaaa ggtttatatc atctaattaa
    26521 agctatatct atgttaaaga acaaagataa tgttgttgtg tacatcttag gacatgggac
    26581 aaaaaaagaa ttattagaaa atttaataaa agcatatcaa ctacaaaacg taatattttt
    26641 gctaggtggc caatcaaatc cttataaata catgtcacgt gcagatttat atgtcatgcc
    26701 atctataact gaaggttttc ctaatgcatt agttgaagca atgtctacag aaactgctgt
    26761 cttatgtgca gattgcaaat ctgggccaag agaaatatta tcgaatagaa cgctagacac
    26821 gatttgtgaa aatatagaat atgctgaatc aggcatatta gtatgtccaa tgacagacag
    26881 tagaaattat tcgccccaat atgaagaatg tgataaaaat ttagcgaatg ctatagaaga
    26941 attgattgaa aacgataatt tgaggaataa gtatgcaaaa gcagcaaaaa agagagcaga
    27001 actatatagt tatgatgcct ttgaacataa cttgttgcaa attatgaaga catttaatta
    27061 attcatatga tgaaataaaa ataagggagt ataactagat gctgaaaaaa aatacatctt
    27121 tacagaataa aacaatatta ataactggcg cagccggttt tattggatca aatttggttc
    27181 ttgagttatt acgtactcag tcatcaataa aaatcattgg cattgacaat atgaatgatt
    27241 actatgatgt ctctattaag aactatagat tatcagagat agaaacggag gcaaagaacc
    27301 atccaggatc tacttggaat tttatcaaag gttctattgc tgataaagca acaattgatt
    27361 tcctctttga taattataaa ccaagtatcg tggtgaattt agcagctcag gcaggagtcc
    27421 gttattcaat tactaatcca gatatgtata tcgaatctaa cataatagga ttctataata
    27481 ttcttgaagc ttgtcgtcat tcatatgata atggagaatc tggtgtggaa catttagtgt
    27541 atgcctcatc gtcttccgtt tatggtacta ataagaaaat tccttattct acagaggata
    27601 aagtagacaa tcaagtatcg ttgtatgcag caactaagaa aagtaatgaa tcaatggcac
    27661 atgcatattc taaactttac aatattccgt ctacagggct acgtttcttt acagtatatg
    27721 gtcctgctgg tcgtccagat atggcttatt ttggttttac tgataaactt cgtgctggtg
    27781 ataatatcca aatattcaat tatgggaatt gcaagcgtga ctttacctat atagatgata
    27841 ttgttgaagg agtaaagagg gttatgcagt gcgctccaga gaaaattgat ggggaagatg
    27901 ggctaccaat cccaccatat catatttata atattggtaa caatacgccg gaaaacctac
    27961 tagattttgt agatattcta caacaagagc taattgcagc aggggtgcta ccagaagatt
    28021 acgactttga atctcatacc gaactagttc caatgcaacc aggagatgtg ccagttactt
    28081 atgcagatac tagtgcgtta gaacgagatt ttgaatttaa accaagtaca agtttgcgtg
    28141 acgggcttcg taaatttgcg cagtggtata agtcttttta tgaagtataa ttgtattttt
    28201 ttacttataa aagtttatag aaacacctca gacactacaa atctgaggtg ttatttttta
    28261 atctcgttga aataaatctc tggtatatac tttttctttt acatcatcaa gattactatc
    28321 gtaacgatta gcaataatac tgtgactgat atttttaaaa tcatctaaat tatttattac
    28381 ttttgaacca aaaaatgtag tgttattttc aagtgttggt tcataaatta caatagttgc
    28441 cccctttgct ttaattcgct tcataactcc ttgaatagat gactgacgga agttgtctga
    28501 attactcttc attgtaagac ggtatacacc tatgactacc tctttttctt tttctgcatt
    28561 ccacgaactg ttagcctcat acgtgccagc aagttctaac actcgatctg ctataaagtc
    28621 ttttcttgta cgattactat cgacaattgc acttatcata ttctgaggaa catcgttata
    28681 gttagtgaga agttgttttg tatctttcgg taaacaatag cctccatatc caaaagatgg
    28741 attattataa tgtgtgccaa ttcttggatc taagcaaacc ccgtgaatga tttcttgtgt
    28801 atttagtcct ttcatttctg cataagtatc cagctcattg aagtaagata ctcgaagtgc
    28861 aaggtaagta ttagcgaata atttaactgc ttcagcttct gtgaatccca tgaaaagagt
    28921 ttcgatatct tttttgattg ctccttcttg gagtaaatct gcaaaagtgt gagaggcttc
    28981 tcgtaaagtt ttgtcagttt ggtccgtgcc gacaataatt cgcgaaggat atagattgtc
    29041 atataatgcc ttagattctc tgagaaattc tgggctgaat agaatatttt tagtattgta
    29101 ttttttacga atactttcgg tatagcctac gggtaccgtc gacttgatga ccattattgc
    29161 ctttggattg acttctaaca ccaatttgat tactgactct acagcagaag tatcaaaata
    29221 attttgttta ctatcataat ttgttggagc agcaatgaca acaaaatcgg cttctctata
    29281 ggcggctgca ccatcagtcg ttgcaattaa attaagattt ttttcagcta gatatttttc
    29341 aatgtaatcg tcttgtattg gagatttctt attgttaatt tgttttactt tttcaggaag
    29401 aatgtctact gctgttacct gattgtgctg ggcaagaaga gtagcaatgg aaagacctac
    29461 gtaaccagta ccggctacag caatattctt cgactgatgt tttgttctgt ttgatttatt
    29521 tgattcattt ataaatagat ctgttggttc aaaatttaga acttctgcta atgattctaa
    29581 ttgttgtatt gacgggataa aatcgagaga ttctactcga ctaattaagg cacggttgat
    29641 accagtagct actgcaagtt gttgttgtgt cattttcaga gattttctag aatcaataat
    29701 gatttgagct aaacgttttt gagataactt tttcatgatg cactcctttt tttgttgcta
    29761 ataataacaa acaatttttt cttctataac agaatagctt attattaata aaactgtcaa
    29821 tttttttatt gattaaaaag atattttttg attttaagta ttttcaatta ttttttgtta
    29881 cttaaaataa ctttatagat tgtgaataac tttatacata aaaagtttac gtgagtccat
    29941 acaatataaa gaataaaaaa tgtgatgttt taaactgtaa ccaaccataa taaactgctt
    30001 ctcaattctc cctcatacgc aatacatagg cgtcaagcag gattctcgcg atgatctgga
    30061 gaggcaagcg tgaacgtact tcataatcag ggaaataaga accttctgat ttgaaaccta
    30121 cgagatttat ctcgcaataa tctttgagtg tagaggaatg attggctgta actagaatcg
    30181 aaccaatctc tgcatcatag cagttctttg cggcggtgac gagttctttt gtctcgccgt
    30241 tcaaagaaac aaaaataacg ctgtctttct tagttagttt ccgactgatg cttttgataa
    30301 tctctggatc agtatgcatt tgacaatttt ttcctgttaa ttgaagtttt acgagcatct
    30361 cttgaccaat catttctgaa aatcctcggg caaagacaaa aacccggtca gtaaatttga
    30421 ttctttgtat tgcatcttca atgttcccga tttccaacat attgatcgta cgtaccactt
    30481 cttgttcatt ttttagaatg gctcgacgga tacctttgtc tactttatct aaaaagaaaa
    30541 attgatgttc ttgttttctc cttcttttag atggtgctta aacgaagtaa atccttcata
    30601 gccttttttc ttcattgtcc gcacaatggt ggctgttgag acatttgctt gttcacttag
    30661 tttcacgatg gagtagttag ggatctctag gatgtggtgt tcgataaagt tccagaggta
    30721 ctgttctgtt tcacttaatt tgtgatccat attctttcct tctttcacta aaagttagtt
    30781 aaaaaatagc acgatgtgtt tataaatgta aaggttttct ttgtgttgga acgattaaga
    30841 aaacattttc tctttcgcgt atttcataat agattcaagg aggtcattgg ttatgtctat
    30901 ctacacatgc acgatgaatt tggcaattga tctatttatt gaaacagagg agatgcatcc
    30961 ttttatggta aaccgtacaa aggaggatga cattcaggca aacggaaaag gagtaaatgt
    31021 gtcactagta ttaaagatgc tagatttccc aagtacggca ttaggttttt ctgctggttt
    31081 cacaggaaaa tatatagaag actatttaca gaagaaacaa atccaaacag agtttattga
    31141 agtgcctggt atgacgcgta tcaatgtatt tacacaagtc aatcaaacga gagaagaata
    31201 caaattagtg aatcaaggac ctgaaatacc gcaggcagct gtccataatt ttttaaatca
    31261 aataagagca ttacaagcag aggattatct ttgtgtttct gggagtttac caagaggaat
    31321 gtctccgaag gttttagtgg aaatcagtcg gatttgtcag gaaaaggaga ttcatttgat
    31381 tattgatagc agtgatcaag aggtcatgga ttgtttgccc tatcgaccat ttttgctgaa
    31441 accgaatgag gaagaacttt cttcttggtt cggacgaaaa atggttacag atgaagatta
    31501 ctttgtttat ggacaacgac tggtagagtc aggtgcagaa aatgttttgt tatcccttgg
    31561 tgagaaagga gcgattcttt ttacgaaaga cagggtgatt cgaggaaact cgccaaaagg
    31621 aaaagttgtc aatacagcat gtgcaggtga tgccatgtta ggcacttttt tagtaggata
    31681 catgaatcga cgaccgcttg atgaaacgtt acgtaaaagc atagcagcag gcagctctac
    31741 tgcttttcgt aaaggactga ctgatttttt ggatgtggag gaattaagta aacaaatcaa
    31801 aatcaaggaa gagaggttcg aaagatggga aaatatcaac taattgcagc aaccggttgt
    31861 ccgacaggaa ttgcacacac ctacatggcg caagaggcat tagagcaagc agctagaaaa
    31921 aaaggcatca cgatcaaagt ggagacccat ggacaaattg ggatcgagaa tgaattaacg
    31981 gctgaagaaa tcaaacaggc agatgctgtc attattgccg cagacaaaga tgtccattca
    32041 gaaagatttg cgggaaaacg agtcattgat gtttctgtca gtacaggaat caaggatgca
    32101 caacggctga ttgacgaagc attggcagga aaagggacca tcttagcaga taatgaagct
    32161 gttgatactt tagaatcaga aacgataagt ggtgctaatt ttggtcgcag catctataaa
    32221 aatttaatga atggcgtctc tcatatgttg cctttcgtgg tagctggcgg agtattgatt
    32281 gctatttcat ttgccgtttg gggaatctat tcttttgatc cagaccatgc acaatacaat
    32341 gctacagcgg cgatgttaaa aacggttggc gatgcagcaa tggggatgat ggttccagtt
    32401 ttagcagctt atattgcaga agggatcgcg aaacgtccag ggttagtcgt tggatttgtt
    32461 ggtggaatcg tggccatgag tggcggtact ggatttttag taggtatttt agctgggttc
    32521 ttagcaggtt attttatctt atttttgcaa aagctactga caattttacc taaacaacta
    32581 gatggcttga aggcaatctt cttatatcca gttattggtg tagtgtttat cggcatcgtg
    32641 atgtctttgc tggcgggtcc aatgaaggct ataaatgaag gaatgatgag ctttttagct
    32701 ggatttgaac attcgaatcc acttgttctt ggcgtgattg ttggttgcat gtgtgcgttt
    32761 gatatgggag gaccgattaa taaggcggca tatgtaacag gtacagctct tttggcacaa
    32821 ggaaacacga cttttatggc tggcgtgtca gtagcttgca ttgcaccacc gttgattact
    32881 ggttttgcaa ctttattgtt tggtaaatat tttgatacta atgatcgtaa tgcaggtttg
    32941 gttaatttta ttttaggatc aactcatatt acggagggag ctattccgtt tgctgcgaaa
    33001 gacccgatcc gagtattacc aacgatgatg ttaggctcat caattgctgc tgtcttgacc
    33061 tatctgtttg gtgtccaagt accagcccca catggcggtt ttttagtgtt acctgtagtg
    33121 acgggaaaaa tccaatgggt tacagcgatt cttattggtt cgatcgttgg tggagtgata
    33181 ctaggtttga tccaaaagaa aagagtaact gataaagaca agaagatgga taataaagca
    33241 gcaaatcgta cagttatcga agaaggaaga gcaggaggct tatcatgaca atcattcatg
    33301 aagagaacat ttttttacaa cagccattag atagtcaaga agaagcattt aagtttttag
    33361 caaagcaaac attctgttta ggaatcgctc atgacgaaaa agaagtatat cgaaaacttc
    33421 tagaaagaga aaaagaaggt actacaggaa taatgtcagg ttttgctatc cctcatgcga
    33481 agtctcaaac aatcaacgaa cctagtatga ttatcgtcac actgaacaaa ggaattgaat
    33541 ggaacagttt agatagacag tcagttgatt ttatttttgc gttatttatt ccagattcag
    33601 aagcaggaac gactcatttg aaattattgt ctctcgttgc acgatcattg atgcgaaaag
    33661 aggttacaga acagttgaga aaagcaaaat caaaaacaga aatagccaca atattaacta
    33721 aagaaatagg tgaagatcta tgaagaagat gagtatagaa aagcaggaac gtttgaagcg
    33781 attgacggat gaagctggaa ttattagcgc gttagcaatc gaccagcgtg gtgctttgaa
    33841 gaaaatgatc aaccaatata aagaagctac atcagaagac atcatccaat ttaaacagat
    33901 ggtttctcaa tacctgactc cctatgcctc agctatttta cttgatccag aatgcggcct
    33961 gcctgcagca gcgcttagag agaaagaatg tggcttgctg ctagcttatg aaaaaaccgg
    34021 ctatgatacg aaaatgccgg gaagattacc tgatttattg aatatttggt cggtgaaaag
    34081 gttaaaagaa gctggtgcgg atgcttgtaa atttttattg tactatgacg tggatgaacc
    34141 agcagagatt aatgtgcaaa aacaaatagt tatagaacgg attggttcag aatgcgatgc
    34201 agaaggcata cctttctttt tagagatcct ttcttatgat gcaactattg gcgatccgtc
    34261 ctctcttgcc tatgcaaaag taaaacccca taaagttatt gaagccatgc gagaattttc
    34321 aaaagaacgt tatcaagtgg atgtattgaa agtagaagtg ccagtgaata tgagatttgt
    34381 ggaaggatat gggcaagaga cttgttatag tcaagcagag gcatccgcgt atttctatga
    34441 acaatcgaaa gtgactgaac aaccgtttat ttttttaagt gcgggagtca atgctacgtt
    34501 atttcaagat acattacgtt ttgcaaaaca atcaggttcg acattcaatg gtgtcttatg
    34561 tgggcgagca acatgggcga agggagtggc accttttgtt accgaaggcg aagaaaaagc
    34621 gagtagttgg atgttagaag aaggaaaaca aaatattaag gaattaagta cactattaaa
    34681 agaaacagca acacctgtct acgttgatag ataagaaaaa gttgtttctt cataaaaaga
    34741 tgctgctgca attagatagc gatcaatcga tgattcaaat tatacattca cttaaataaa
    34801 aatatcgact agatttcttt ttcaaaaatc ttggtcgata tttttaattg ctaaaactgt
    34861 taatgaattt ttattacact cttatttact atctacttcc gcttctgctg ctttcctgcg
    34921 ttgcggcctt tgttatttgt actgtttttt ggttgtttga tttgttttgt tgcttgtttg
    34981 ttgtcagctg gttttgctga ttctgtcacg tcttttcttg gagtgacgac ttgttttggc
    35041 gggttttgtt tcaactcttc tgccacttgt gctttcaagc gtggtttcat cataacgttt
    35101 gtgatgaatg tttgcagaca gctgaacaca ccaccgacta cccagtaaag tgtaacgccg
    35161 gctggcgcac tgatcgacat gaagacgatc atagcaggag agacgatcag catcgtacgc
    35221 atcgtctttt tctgttcttc aggaataccg attgttgaaa tatatccttg aagcagataa
    35281 gcgacccctg caatggccac aagcaccata cttggtgagc ctagatcgat gccgtaaaaa
    35341 gatgattcac ggataccttc tgtgtagcga gccgtaaaat acaaggcaga gaagatcggc
    35401 atttggatca atagaggcag acagccgatt ccgccggtca tactcaatcc gttttcgcga
    35461 tatacttgct gcatttctgc ttgtgctgcc atttgttctt cacgtgttgt tgcagctttt
    35521 agcttttgtt gtgctgcttc aacttgtggt tttaacgctt gcattttttc agattggatc
    35581 attgtttttt tcgattgact gatacctagt ggcaagatga tgatacgaac gatcacagtc
    35641 attgcaataa ctgcccagcc gtaagaccaa ttgaaattct caactagata tgtaatcgct
    35701 tggcccatag gatggacgag tactcgataa acgattcctg aagtgtcagg gtttccgttt
    35761 gaatccatcc gcacacagcc agataaaaag agcaggatac tgacaagtcc ggatcccaat
    35821 aaccagtttt tccatttatt catagaatac ttcctcttct ataattttta cacaaactta
    35881 actatactaa aaaagcgcat ggaattcaat caacttcata gaaatttcat ataaatattc
    35941 tttctttttc gtagcgaaaa attttgaaaa aagacaaaaa atcaagaaag aaatacttgg
    36001 aaagaaaaga gtgattccaa gtgtttcttt cttatataaa aaactaaaaa cttttttgtt
    36061 ctgtctggaa aatatgggtt aagcaaattt attgcaagtt atagatcagc ttttttacta
    36121 cctatcttta atacttgagg caaagcgcct caaaaacaac ctgatcgacg gtgttcaaaa
    36181 gtcagtttct cggtattaag tcaaatttat gcaaaaatgt ggaaagccat tttcacaaaa
    36241 ttttccttaa tactcaaaac taagcgacct tttcacaacc ttatcccacc acatcaaatt
    36301 tctttcgttc ctcaatcatc ggatcttctt ggacatccac atactgcact cgtccacttg
    36361 ggctcggaga cttcttgact tcttcgataa atttttggat gatgtcgtca tttccgattg
    36421 cttcgattgt gactgagccg tcgtcttcgt tttttaccgt tccggtcacg cctaactgat
    36481 cagcaaccat cttggtcata tagcgaaatc ccacgccctg gacacgtcct tggacattca
    36541 ttttaacttt gcgcatgttc gtcacctttc tttcctgttt tataaatcaa tgataccgat
    36601 ttttttagga tgaaacaagc tcaagcacct attccatgat ataatcaggt gaggtgaagg
    36661 aatgtgaaag agatccaatc agcaaaaaat ccaaaaatca aagaattaaa aaagctacat
    36721 aaaaagaaat acagagaaga aaaggcagaa tatcttttgg aagggttcca tctgatcgaa
    36781 gaagctgcgt cgtctgatgc agaaataaaa gaactttttg tgacacagag aggtatgaaa
    36841 gaatggggag actggctggc tgtaaacaaa gagatttcta cttttctagt ttcagatgag
    36901 gtcatgaccg ctatgtcaga tctacctaca ccgcaaggga tcttagcggt gatgacgtta
    36961 acatctgaag atacgccaga tttttcagga ggctggcttt tactagataa tgtacaggat
    37021 cctggaaatg tgggaacgat gatccgtacg gcagatgcgt ttggtatggc tggtgtttta
    37081 ttaggtaaag gaacggcaga tatttatagt acaaaggtgc tgcgaagcat gcagggaagc
    37141 aattatcatt tgcctgtgtt acaaaaagat ttggcagaag tgatccctgt aatgaaaggc
    37201 aaagggttta cggtgtacgg tacagaatta aatgaagaag cacatgcatt agacaaagta
    37261 gaaaaaacag aggatttcgc tataatcatg ggaaacgaag gtcagggagt aagtcaggaa
    37321 atcttgtctt tgactgatca gaacgtatat atcccaatga aaggaaatgc ggaatcattg
    37381 aatgtcggag tcgcagcagg gatcgttctt tatcattttt ctttatgatt aaggaactat
    37441 taagctttag ctattttatc tagagcgact agaataatcc gaacactggt ggtatactta
    37501 gatcaatttc agaagaaaat gaaattcaaa aaggtggcag atcgataatt atgacagaaa
    37561 aatggcgtga agacgaagaa tatatgtctt atgtacaaga tcttttagaa acagaagcag
    37621 tgaaaaaatt agcgaattac acacagcatg ttcattccac tcgtttggag cattccatca
    37681 gtgtttctta ctatagttat ctgctcgcaa aaaaatgggg tggcaatgct aaagcaacag
    37741 cgcgtgctgg acttttgcat gatctgttct actatgattg gcgtacgacg aaatttgacg
    37801 aggggacaca tgcgtatatc catccaagaa ttgctgtaaa gaatgcagaa aaaatcaccg
    37861 atttgtcgga tcttgagcga gatatcattt tgaagcacat gtggggtgca acgatcgcac
    37921 cgcctaagta taaagaagga tatattgtga cattcgtgga caaatactgc gcagtcaaag
    37981 aagcggctca gcccatgtct gcaagtatgc gtaagagatg gcaacgttac tttgggaaag
    38041 aatcctcgat ttaacaggta aaaccaataa tagaccatat tgaggttgtg acagaagtgg
    38101 tcagcttcaa gaaataagaa ggaatttacg aaaattactt ctcaaatttt tgtgaagttt
    38161 cggcttatta ccgcagatgc aagcttttga acaccattca ttcgaaacaa gggactttga
    38221 cacgactttt gtcacagtcc ttttttctgt ttgcagttga ctatctgttc aagatacggt
    38281 ttacttttat ttatcgaatg aatcatgtac atagaagaat aagcattaaa gggggtgatg
    38341 ataagatgca aaacgtatct tatttaaaag agtccgggat cttcaggtaa cacatacttt
    38401 gcagaagatc acttttttct acaaagtatg cactttggtt agaagaaagg actttaaaat
    38461 catggaacaa acaataaaac cataccaata tttttttata aaaagagaag tagaacagtt
    38521 attaaatgcg tactcatctg tcaatgatcc aaaaacggta caaacagttc aggcactagc
    38581 aactgaaaag attcgagaca tattagaaca cgaactgcca gaaatcgata catttttaac
    38641 gacagtttta gacgtaaaac tgacaaaagc gcaagcagaa cgagcattgg aggagctgaa
    38701 gcaaatcgtt cagccgttta tgcagcctag caaaccacaa atcgagaaat tattccgaaa
    38761 agtgaaaaaa ctcaaacaac cagcttggaa tgaaatcgac ttgcaagaac atacgtacat
    38821 cggctggaat gatccaggta cgcagaaaaa attcatgatc tattacgaag atgaaaaatt
    38881 aaaagggatt agtggtactt tatcaccaac gataaataag ggaatctgtg caatctgtca
    38941 gaaaacatcg aatgtttcgc tttttctttc tacaacgaaa gcaggttctg atggcacgta
    39001 tacgaaaaag gggaattata tttgtcatga tagtgaccaa tgtaatcaac agttaacgaa
    39061 attggctcct ttctatgaat ttgctgaacg tgtaaagaaa gaacgataat tttattgttt
    39121 tttacagaaa aatatgctat cttttaatgg aagtgaatag gtgatggtgt tcgcctttaa
    39181 atgctaacga aagatagcta atgacgccta ctaaagtctg gggacagccc cttt
//
LOCUS       DAFELK010000022        39013 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFELK010000022
VERSION     DAFELK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.023"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            6..305
                     /locus_tag="LP433_001372"
     CDS             6..305
                     /locus_tag="LP433_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2005544.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="LP433_001373"
     CDS             378..1739
                     /locus_tag="LP433_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL2005545.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="LP433_001374"
     CDS             1761..2021
                     /locus_tag="LP433_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005546.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="LP433_001375"
     CDS             2035..2787
                     /locus_tag="LP433_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBL2005547.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="LP433_001376"
     CDS             complement(2881..3486)
                     /locus_tag="LP433_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2005548.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="LP433_001377"
     CDS             complement(3539..4513)
                     /locus_tag="LP433_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBL2005549.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="LP433_001378"
     CDS             complement(4891..5610)
                     /locus_tag="LP433_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2005550.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP433_001379"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP433_001379"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL2005551.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="LP433_001380"
     CDS             7161..8558
                     /locus_tag="LP433_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2005552.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDFFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="LP433_001381"
     CDS             8639..9079
                     /locus_tag="LP433_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2005553.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="LP433_001382"
     CDS             9227..9553
                     /locus_tag="LP433_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2005554.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="LP433_001383"
     CDS             9554..10303
                     /locus_tag="LP433_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005555.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="LP433_001384"
     CDS             complement(10383..10838)
                     /locus_tag="LP433_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL2005556.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="LP433_001385"
     CDS             complement(11265..11540)
                     /locus_tag="LP433_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005557.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="LP433_001386"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="LP433_001386"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBL2005558.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP433_001387"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP433_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL2005559.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="LP433_001388"
     CDS             14770..17436
                     /locus_tag="LP433_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2005560.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="LP433_001389"
     CDS             17800..18552
                     /locus_tag="LP433_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2005561.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="LP433_001390"
     CDS             complement(18574..19728)
                     /locus_tag="LP433_001390"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBL2005562.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="LP433_001391"
     CDS             19913..22354
                     /locus_tag="LP433_001391"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBL2005563.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="LP433_001392"
     CDS             complement(22684..23388)
                     /locus_tag="LP433_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005564.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23575..23820)
                     /locus_tag="LP433_001393"
     CDS             complement(23575..23820)
                     /locus_tag="LP433_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005565.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23837..24688)
                     /locus_tag="LP433_001394"
     CDS             complement(23837..24688)
                     /locus_tag="LP433_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2005566.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24854..25858
                     /locus_tag="LP433_001395"
     CDS             24854..25858
                     /locus_tag="LP433_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBL2005567.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26099..26455)
                     /locus_tag="LP433_001396"
     CDS             complement(26099..26455)
                     /locus_tag="LP433_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2005568.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26823..28010
                     /gene="tuf"
                     /locus_tag="LP433_001397"
     CDS             26823..28010
                     /gene="tuf"
                     /locus_tag="LP433_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL2005569.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="LP433_001398"
     CDS             complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="LP433_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL2005570.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30815..31576)
                     /locus_tag="LP433_001399"
     CDS             complement(30815..31576)
                     /locus_tag="LP433_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2005571.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31743..32375
                     /locus_tag="LP433_001400"
     CDS             31743..32375
                     /locus_tag="LP433_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBL2005572.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTNLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            32434..33294
                     /locus_tag="LP433_001401"
     CDS             32434..33294
                     /locus_tag="LP433_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBL2005573.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33479..35794
                     /locus_tag="LP433_001402"
     CDS             33479..35794
                     /locus_tag="LP433_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2005574.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35976..37817
                     /locus_tag="LP433_001403"
     CDS             35976..37817
                     /locus_tag="LP433_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBL2005575.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37841..38950
                     /gene="rpoD"
                     /locus_tag="LP433_001404"
     CDS             37841..38950
                     /gene="rpoD"
                     /locus_tag="LP433_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBL2005576.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
BASE COUNT        12557 a         6863 c         8086 g        11507 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaaaatta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag atttttttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcacttgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
    23581 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
    23641 gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
    23701 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
    23761 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
    23821 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
    23881 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
    23941 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
    24001 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
    24061 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
    24121 catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca aggaaaactt
    24181 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
    24241 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
    24301 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
    24361 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
    24421 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
    24481 taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg tatccttggg
    24541 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
    24601 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttgata
    24661 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
    24721 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
    24781 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
    24841 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
    24901 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
    24961 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
    25021 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
    25081 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
    25141 agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
    25201 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
    25261 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
    25321 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
    25381 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
    25441 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
    25501 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
    25561 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
    25621 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
    25681 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
    25741 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
    25801 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
    25861 atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
    25921 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
    25981 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    26041 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    26101 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    26161 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    26221 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    26281 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    26341 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    26401 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    26461 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    26521 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    26581 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    26641 tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    26701 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    26761 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    26821 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    26881 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    26941 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    27001 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacgcgcata
    27061 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    27121 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    27181 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    27241 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    27301 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    27361 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    27421 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    27481 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    27541 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    27601 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    27661 tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa ccaggttcca
    27721 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    27781 gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca actgatgtta
    27841 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    27901 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    27961 aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    28021 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    28081 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    28141 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    28201 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    28261 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    28321 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    28381 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    28441 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    28501 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    28561 tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    28621 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    28681 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    28741 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    28801 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    28861 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    28921 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    28981 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    29041 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    29101 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    29161 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    29221 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    29281 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    29341 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatctg gcagattgta
    29401 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    29461 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    29521 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    29581 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    29641 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    29701 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    29761 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    29821 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    29881 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    29941 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    30001 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    30061 cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga tttccattaa
    30121 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    30181 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    30241 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    30301 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    30361 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    30421 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    30481 aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag gattctgctt
    30541 ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca cagagataag
    30601 accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    30661 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    30721 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    30781 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    30841 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    30901 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    30961 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    31021 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    31081 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    31141 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    31201 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    31261 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    31321 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    31381 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    31441 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    31501 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    31561 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    31621 tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    31681 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    31741 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    31801 ttattggtgc ggtgttgttt ttaggaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    31861 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    31921 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacaaatctc atgcagagct
    31981 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    32041 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    32101 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    32161 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    32221 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    32281 gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa atgaatgaaa
    32341 aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt tcaatcatga
    32401 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    32461 caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    32521 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    32581 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    32641 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    32701 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    32761 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    32821 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg cgctcaatta
    32881 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    32941 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    33001 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    33061 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    33121 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    33181 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    33241 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    33301 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    33361 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    33421 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    33481 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    33541 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    33601 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    33661 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    33721 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    33781 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    33841 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    33901 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    33961 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    34021 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    34081 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    34141 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    34201 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    34261 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    34321 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    34381 gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    34441 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    34501 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    34561 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    34621 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    34681 tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    34741 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    34801 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    34861 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    34921 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    34981 acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    35041 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgcag
    35101 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    35161 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    35221 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    35281 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    35341 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    35401 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    35461 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    35521 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    35581 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    35641 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    35701 cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    35761 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    35821 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    35881 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    35941 acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt cctcaagagg
    36001 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    36061 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    36121 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aaaggcggaa
    36181 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    36241 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    36301 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    36361 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    36421 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    36481 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    36541 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    36601 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    36661 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    36721 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    36781 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    36841 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    36901 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    36961 gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta gtcgttccag
    37021 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    37081 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    37141 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    37201 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    37261 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    37321 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    37381 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    37441 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    37501 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    37561 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    37621 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    37681 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    37741 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    37801 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    37861 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    37921 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    37981 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    38041 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    38101 tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    38161 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    38221 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    38281 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    38341 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    38401 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    38461 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    38521 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    38581 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc ttgaaacgcc
    38641 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg aagcaacaag
    38701 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    38761 attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg atggccggac
    38821 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    38881 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    38941 cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    39001 taaaagaaaa aaa
//
LOCUS       DAFELK010000023        37868 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFELK010000023
VERSION     DAFELK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.024"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            188..418
                     /locus_tag="LP433_001405"
     CDS             188..418
                     /locus_tag="LP433_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBL2005577.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            515..1816
                     /gene="murA"
                     /locus_tag="LP433_001406"
     CDS             515..1816
                     /gene="murA"
                     /locus_tag="LP433_001406"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL2005578.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1829..2005
                     /locus_tag="LP433_001407"
     CDS             1829..2005
                     /locus_tag="LP433_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL2005579.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2140..2436
                     /gene="yidD"
                     /locus_tag="LP433_001408"
     CDS             2140..2436
                     /gene="yidD"
                     /locus_tag="LP433_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBL2005580.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2621..3088
                     /locus_tag="LP433_001409"
     CDS             2621..3088
                     /locus_tag="LP433_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2005581.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3173..4057
                     /locus_tag="LP433_001410"
     CDS             3173..4057
                     /locus_tag="LP433_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2005582.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4171..4407
                     /locus_tag="LP433_001411"
     CDS             4171..4407
                     /locus_tag="LP433_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBL2005583.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4495..4575
                     /locus_tag="LP433_001412"
     tRNA            4495..4575
                     /locus_tag="LP433_001412"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4529..4531,aa:Tyr,seq:gta)
     gene            4582..4653
                     /locus_tag="LP433_001413"
     tRNA            4582..4653
                     /locus_tag="LP433_001413"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4614..4616,aa:Gln,seq:ttg)
     gene            4778..4948
                     /locus_tag="LP433_001414"
     CDS             4778..4948
                     /locus_tag="LP433_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005584.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5168..5875
                     /locus_tag="LP433_001415"
     CDS             5168..5875
                     /locus_tag="LP433_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2005585.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5934..6578)
                     /locus_tag="LP433_001416"
     CDS             complement(5934..6578)
                     /locus_tag="LP433_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBL2005586.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6704..6991
                     /locus_tag="LP433_001417"
     CDS             6704..6991
                     /locus_tag="LP433_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005587.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7099..7419
                     /locus_tag="LP433_001418"
     CDS             7099..7419
                     /locus_tag="LP433_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2005588.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7500..8813
                     /locus_tag="LP433_001419"
     CDS             7500..8813
                     /locus_tag="LP433_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL2005589.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8810..9529
                     /locus_tag="LP433_001420"
     CDS             8810..9529
                     /locus_tag="LP433_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBL2005590.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9657..10208
                     /gene="raiA"
                     /locus_tag="LP433_001421"
     CDS             9657..10208
                     /gene="raiA"
                     /locus_tag="LP433_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBL2005591.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10430..12964
                     /gene="secA"
                     /locus_tag="LP433_001422"
     CDS             10430..12964
                     /gene="secA"
                     /locus_tag="LP433_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBL2005592.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13090..14191
                     /gene="prfB"
                     /locus_tag="LP433_001423"
     CDS             join(13090..13161,13163..14191)
                     /gene="prfB"
                     /locus_tag="LP433_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBL2005593.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14296..14982
                     /gene="ftsE"
                     /locus_tag="LP433_001424"
     CDS             14296..14982
                     /gene="ftsE"
                     /locus_tag="LP433_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBL2005594.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14966..15859
                     /locus_tag="LP433_001425"
     CDS             14966..15859
                     /locus_tag="LP433_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2005595.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            16011..17459
                     /gene="cls"
                     /locus_tag="LP433_001426"
     CDS             16011..17459
                     /gene="cls"
                     /locus_tag="LP433_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL2005596.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17796..18653
                     /locus_tag="LP433_001427"
     CDS             17796..18653
                     /locus_tag="LP433_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBL2005597.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18768..19688
                     /gene="pstC"
                     /locus_tag="LP433_001428"
     CDS             18768..19688
                     /gene="pstC"
                     /locus_tag="LP433_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBL2005598.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19688..20572
                     /gene="pstA"
                     /locus_tag="LP433_001429"
     CDS             19688..20572
                     /gene="pstA"
                     /locus_tag="LP433_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBL2005599.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVSEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20587..21393
                     /gene="pstB"
                     /locus_tag="LP433_001430"
     CDS             20587..21393
                     /gene="pstB"
                     /locus_tag="LP433_001430"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL2005600.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21409..22167
                     /locus_tag="LP433_001431"
     CDS             21409..22167
                     /locus_tag="LP433_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL2005601.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKNKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22180..22857
                     /gene="phoU"
                     /locus_tag="LP433_001432"
     CDS             22180..22857
                     /gene="phoU"
                     /locus_tag="LP433_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBL2005602.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23094..24125
                     /locus_tag="LP433_001433"
     CDS             23094..24125
                     /locus_tag="LP433_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL2005603.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTNQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKHGLFALGSLIINIVLLLLLLLIFTKIEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNLWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            24122..24889
                     /locus_tag="LP433_001434"
     CDS             24122..24889
                     /locus_tag="LP433_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL2005604.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24989..26557
                     /gene="liaX"
                     /locus_tag="LP433_001435"
     CDS             24989..26557
                     /gene="liaX"
                     /locus_tag="LP433_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBL2005605.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26854..27174
                     /locus_tag="LP433_001436"
     CDS             26854..27174
                     /locus_tag="LP433_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBL2005606.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27174..27524
                     /locus_tag="LP433_001437"
     CDS             27174..27524
                     /locus_tag="LP433_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL2005607.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27691..28629
                     /locus_tag="LP433_001438"
     CDS             27691..28629
                     /locus_tag="LP433_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBL2005608.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28644..29474
                     /locus_tag="LP433_001439"
     CDS             28644..29474
                     /locus_tag="LP433_001439"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBL2005609.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29518..30543
                     /locus_tag="LP433_001440"
     CDS             29518..30543
                     /locus_tag="LP433_001440"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL2005610.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30558..31496
                     /gene="galU"
                     /locus_tag="LP433_001441"
     CDS             30558..31496
                     /gene="galU"
                     /locus_tag="LP433_001441"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL2005611.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31621..32061
                     /locus_tag="LP433_001442"
     CDS             31621..32061
                     /locus_tag="LP433_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBL2005612.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            32064..32666
                     /locus_tag="LP433_001443"
     CDS             32064..32666
                     /locus_tag="LP433_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL2005613.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32725..33831)
                     /locus_tag="LP433_001444"
     CDS             complement(32725..33831)
                     /locus_tag="LP433_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL2005614.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            34041..35042
                     /gene="ccpA"
                     /locus_tag="LP433_001445"
     CDS             34041..35042
                     /gene="ccpA"
                     /locus_tag="LP433_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBL2005615.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(35379..37724)
                     /locus_tag="LP433_001446"
     CDS             complement(35379..37724)
                     /locus_tag="LP433_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL2005616.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
BASE COUNT        12333 a         6547 c         8127 g        10861 t
ORIGIN      
        1 tttggaataa gggactgcga caagactttt gtctcagtcc ctttttttgc atatttttag
       61 catttatttc ctaaaaaatg taaggggatt cctatatttt taagtatact tgtttttcct
      121 tttatacatt ttatggtatt atcattttat tagttattat aaaacaatcg ttagaaagga
      181 cgtcattatg caagtatacg gaattgatgc ggtgcttcga atcgtgagtc atttggcgtt
      241 tatctactta gccttctggt ctttacgttc gttacgcatt gaaacttttt tcagaccaat
      301 gcataatacg caaattagaa tggcaatcgt acttttttca atttttttag ggtacactgc
      361 aagtaatttt ttcttagaag ttatcgcttt atgccgaaat cttttcgtta gcctgtaaat
      421 tttaaaaaaa ggtactattt taaaagcaag gatgttataa tagaaaagat tttgagtaag
      481 tgtatgctca ttggaatttt ttggagggaa caacatggaa gagatcatcg taagaggtgg
      541 caatcaatta aatggaacag taagaattga aggagctaaa aatgctgttt tgcctatttt
      601 agctgctagt ttgttagcag aagaaggtat tacgacatta gacaacgttc cgattctttc
      661 tgatgtcttc actatgaatc aagtgattcg tcacttaaac gtagatgtag attttgatga
      721 acaaaagaat caagtaacaa tcgacgcttc aagacaatta gaaatcgaag cgccttatga
      781 gtatgttagt caaatgcgtg cttcaatcgt tgtgatgggt ccgctacttg ccagaaatgg
      841 acatgcaaaa gtagctatgc ctggtggatg tgcgattggt aaacgaccaa tcgatttgca
      901 tttaaaagga tttcaagctt taggagcaaa aattattcaa aaaaacggct atatcgaagc
      961 aattgcggat gaattgatcg gtaacacgat ttatttagat ttccctagtg taggtgctac
     1021 tcaaaatatc atgatggctg ccgtaaaagc aaaaggaaca accatcattg aaaacgtagc
     1081 tcgcgaacca gaaatcgttg atttagcaaa cattttgaat aaaatgggcg ctcaagtcta
     1141 tggagctggt actgaaacaa tgcgtattga aggcgtggat catttacatg cagtcaacca
     1201 ctcaatcgta caagatcgta tcgaagcagg tacctttatg gttgctgctg caatgacaca
     1261 aggcaatgtg ctgattgcag atgctatctc tgaacataac cgcccattga tttctaaatt
     1321 gatcgaaatg ggtgcagaaa tcattgaaga agaaggcgga gtccgtgtca tcggaccaaa
     1381 acatatctta cctacagatg taaaaacgat gcctcatcct ggtttcccta cagatatgca
     1441 agctcaaatg acagctatcc aattagttgc agaaggtaca agtgtagtga ctgaaacagt
     1501 gtttgaaaat cgtttccaac atttagaaga gatgcgccgt atgaacgctc atgtcaaaat
     1561 cgacggaaat gtagcaatca tggatggaaa ccatgaattg caaggtgcag aagtatatgc
     1621 aacagacttg cgggcagcag cagcattagt tttagctggc ttgaaagcaa atggaatcac
     1681 acgtgtgcgt aacttgaatt atctagaccg tggatattat aatttccata tcaaactaca
     1741 gcaattaggt gcagacgttg aacgtgtaga catggatcaa acttctgctg aaaaaacagc
     1801 acaaacgatt gcttaaggaa gtggctgaat gagtaaccaa cgatatatct tattaacttt
     1861 gataaagatt ttaatggtga tcttattgct tatccttctt tttgtggccg gaacgatgat
     1921 cggatatggt gtcatcggtg gcggcaatcc atttaaagta tttcagccaa gtttgtggat
     1981 tcatattcga gacttttttc attgataaat aagaatcaca gtggttctag tcgatatgaa
     2041 gtgagccatg aagcagaaca tgataaaaga aaacagaagg gaacgttgac gttagtcgcg
     2101 atcccttttt ttagtaaaag aaaagaagga atctaattga tgaagaagat attgatttat
     2161 ttagttagag gatatcagcg ctttatttcg cctgcatttc cacctagctg ccgttattac
     2221 ccaacctgtt ccaattatat gataaaagca attcaaaccc atggcgcgct aaaagggacg
     2281 gtaatgggga ctgcacggat cttacgctgt catccttttg tcaaaggcgg tatcgattat
     2341 gtaccattga cattccgatt aacgcgaaat aagaaagata aaaaagaacc agattataaa
     2401 aaggttgtga aaaatacggg tagcactgag cgataaagaa acaatttgga aaatagcttc
     2461 ttatattttg caaaattgtg agttattgcc gaagtgttgg attttgaaca ccgtcaaaaa
     2521 aaaggttgtg aaaaatacgg ctagcactga gcgataaaga aaaagaggaa atttattgtc
     2581 aaagtaacaa ctccgcaact acttatatgg gggacaaaaa atgatcgaag aactaaacaa
     2641 gaaagattta ccatggtcct tgttattaga tgcagatcct gataaagaaa aagttcaagt
     2701 atatgtttcc agagggagtg gctggatatg gaaagaaaaa gaaaaaacaa taggtgtact
     2761 gatctatgtg gcaagggaaa aagaatacga aatcgtcaat gtagcagtaa ccccaacgta
     2821 tcaaggaaag gggattggcg gaaaattact tgagacagct tttcagaagc tttcacaact
     2881 cgcttccagt caaactcaga tcatcatacg aaccggcagt actagcagtg cggcgttaca
     2941 tctctatcaa aaaatgggct atgtggagat tggtcgagtc aaagactatt ttatccatca
     3001 ttactctgag cccatttttg aaaatggaga tcaattaagg gatcaagtga ttttagcaat
     3061 tcacttacct aaaaatagct ttaactaata aaatttcaat tcaagaaaat gctttcaaat
     3121 gctaaataga tacattacaa tagctttagc aaacaaaaag gagaatattt ttatgggaat
     3181 attagttttt gattttggtg gatcggctgt caaatatggt tgttgggatg gcaaagagat
     3241 taaaggtaag ggacaatttg caacgcctga atcttgggaa gaaatgaaag cgcaattatt
     3301 tcaagtttat aaaaaaatac tcgtttcttt tgaagtcgaa ggaattggaa tcagctctcc
     3361 tggagtagtg aataatgaga aacaggtgat tgagggaatc agtgcgattc cttatattca
     3421 tggatttaat attttccgag atttggaaac tctgtttcaa cttccagtaa cgattgaaaa
     3481 tgacgccaac tgtgccggaa tggctgaatt ttatgaaggt gctgcccgcg attatcaaga
     3541 tgttgctttt gttgtggcag gaactgggat tggcggggcg ttgttcacga aaggacaaat
     3601 caataaaggg gcacatcttt acggtggaga atttgggttg atgttcttaa atggcgataa
     3661 gacattcagt aaacttggta cagcggtaca gatggcttgg cgttattgtg aacgcaaagg
     3721 tctcgataaa aatgcttata ccggaaaaga tgtctttgaa ttagcagaaa ctggagatgc
     3781 aatagcaaaa gaagaagttg agagttttta tacgtatctt acaaagggat tattcagtat
     3841 tcaattttcg tttgatccag aagtgatcgt attaggcggc ggggtttctg caaaagaagg
     3901 gctcattgat gagatcaaaa gccgaatgaa gaagctgaca gaacaattcg atctgcatga
     3961 tttcgaaccg cagattttat tatgtgaata cagaaacgat gctaatcttg taggtgcagc
     4021 agcaaactat ctcgctgtac gtcaagggga gaattaagag ctttagagaa ggtgcagctt
     4081 gcataaaaga agtgaatgaa atgaatagga gatttttacc taaggaatgt tttatttgct
     4141 gcagtatgat aaaatatctg agaggtgaaa atgatgtcaa aaaaaaataa agatattgaa
     4201 gtgcgtatag aagaagtgaa aaaagatatc aaaggtaaga attatgaagt cactcagtta
     4261 tttataggga aaaaaatgat tggtgagatc ttagcctatg gaccaaaaga atatgaaatt
     4321 ttctttggtg aagaagattt tggaaaagaa aaaagtcttg aaaatgcgat agaaacagtg
     4381 attcgacact ggaatctgca cgaataaaaa aatatcaaaa aaactttcaa taaagggttg
     4441 caaaaatctg gaaaattagg tattataact aagtcaggtt gatacaaacc tttcggagga
     4501 gtagcgaagt ggctaaacgc gacggactgt aaatccgttc cttagggttc agtggttcga
     4561 atccactctc ctccatttca ttggggtata gccaagcggt aaggcaaggg actttgactc
     4621 cctcatgcgt tggttcgaat ccagctaccc cagtatacca caatcgtaag ctctcgttag
     4681 ttcgagagct cttttttttg ctttgctacc ttgttccttg aagattctgc tgatttaaga
     4741 tagagttaag ttaactacaa gaattggagg gatccacatg aaatggaaag aaaaagtaga
     4801 cgaagcagct gaaaagttat atgatttggt caaatcagaa aaatacaata ttgaagtgaa
     4861 tattccgaaa aaaggcggaa aagcggtccg ggtaaaatca aaacgcccaa cgaatcatac
     4921 aaaaaaatgg atggctaaaa accgctaata ataacaaaag atccataagt cggcattttc
     4981 atcgatttta gggtcttttg ttattttcta ggttggacat atctaaaaaa ttgtttctga
     5041 caataggagt aggaagaacg atgtgtgtct aaatcctctg ttgatggata gaaaccttta
     5101 tctttttcag ttgtgaatca ggtatatacc agttataata gaagaaacga aaggacgggt
     5161 gtacgttatg tcgaatcaat tacctgtata tatacagatt catgaccaat taaaaaatga
     5221 aatcgaacaa ggtatatgga aagtcggaga ccgtcttcct tcagaaagag aattagcagt
     5281 gaaattcaat gtcagccgta tgacgttgag acaagcaatt caaaacttgg cagatgaagg
     5341 aatcttagaa agaaagatcg gttcgggtac atatgttgca cgagaaaaag tacaagaaaa
     5401 aatgtctggt gcaacaagtt ttacagaaat tatggaatca caaaatcgag taccgtctag
     5461 tcggacaatc tcttatttct tgacttcgcc aagctcaagt gaaatggaaa aactaaactt
     5521 gagtaaagat gacacgatct tgcgaatgga acgtattcgt ttcgcagatg atgtccctat
     5581 ttgttttgaa gttgccagtg tgccacaaaa gctgatcgat ggctacagca aagcagagat
     5641 tactgaatcg ttgtatcgca cgctagaaga aaaaggcggg aaaaagatcg gtccagcgaa
     5701 tcaaacgatt actgctgtgt tggcttctga gaaaattgct gactatttag aggtaaaacg
     5761 aggagatgca gttcttcgtt tgcgccagat ttcttatttt gaagacggta cgccgtttga
     5821 gtatgtgcgt acgcaatacg taggaaatcg ttttgagttt tatttggaaa aataaaaaac
     5881 aggtgatccc tgattccgta ttagaaataa aagagaatca gaatcacctg tttttatata
     5941 tgatcagtta ccagttgctc gtgataagaa acaggaccct cttcaaattg gacttgtccg
     6001 ttcagcagct caatgatgga ttctttaaag tggtcagcac ttttttcatc tacagcacag
     6061 atgacgctaa cttgatcagt atattggatt tcttttataa aaaaatgttg gagttcaaga
     6121 taattctgta attttcctag ttgcggatac gtgatcatca cagagatctc ctgttgcaag
     6181 gtaccttcta cgattccaat gtcagacaat gcttgagaga ccgcatgagt gtatgctcgt
     6241 attaatccgc ctgtgccgag tttcgttcct ccaaaatatc gagtgactac tgcagctaca
     6301 ttgatcagtt gatttttttt gaggacttcc aacatcggta tgcccgccgt tccacttggt
     6361 tctccatcat cgctgcttcg ctggatttca tttttttctc caatgatgaa ggcgctgcag
     6421 ttatggttcg ctttccaatg ttcttttttt atttcttgaa tgaaactttt tgcttcgtcc
     6481 tctgattcta ttcgtctaag agaacagata aagcgtgatt ttttgatctc gatctcactt
     6541 tgtccatttt cttttattgt acgatagcgc tcgatcatct tgtcacctct tttttcattt
     6601 tctttattca gtataaataa agttctaggt tgtttcaaca ctgtaacggt tgcgcaattg
     6661 ctgtagtatg cgataataaa gacaaaggca ggtggatctg gggatgcagg aacgaatgaa
     6721 aaagtacgat gcaattacgc attatttgaa gaacaatggc ggctctcaag taacgttgac
     6781 ctttacccaa tttgacgaac tgctgtttcc cagtaacgga cttcccaaaa cagcaaggga
     6841 aagtacagat tggtgggcaa atgattataa acaccctgaa aaaggtgcct atggctggat
     6901 aaatgcaggc tatgaagtag ttgtcatcaa tttggacaaa gaatatgtcg tgttcaataa
     6961 attagtgaaa tctagttggc tatttgatta aataaaccgc gtttagaaaa cgttgacaaa
     7021 tttctttctt tttatataat agagtaacag acgcgaagaa aacgtttgcg tagtttgttt
     7081 taaaaaggag agaaaagtat ggctaaaaaa acaatcatgc ttgtatgttc ggctggtatg
     7141 agcacaagtt tactagtaac aaaaatgcaa aaagctgctg aagcaaaagg aatcgactct
     7201 gatattttcg ctgtgtccgc ttctgacgca gataacaatc ttgcaaataa agacgtggat
     7261 gtgttgttat taggcccaca agttcgcttt atgaaagctg attttgagaa acgtctggaa
     7321 ccaaaaggca ttcctttaga tgtcatcaat atggctgatt atggtatgat gaatggcgaa
     7381 aaagtgttag atcaagcaat cacgctcata ggtgaataaa tagaacagta taactatcga
     7441 acaagcgatc caaaaaatag atcgcttgtt ttttcgtata tttttttagg gcgaataata
     7501 tgaatcattt ttggggtaga aggcttctga cgagagatat taaagcaata gactgtgagg
     7561 aggtaaattt accaaattat gagaagatcg cagcagtgga acgtttgagc aactggattc
     7621 tttgtcatcg ctgtggaatg agaacgtccg tcattgatgg acagcttgca gattacggtt
     7681 atttttgtac acattgtcta tatttagggc gatgcgacac tcaacaagat ttatatttgt
     7741 ttgatcagcc tgaagcaaaa cctcgagaag tcgtcttttt ttggacagga cagcttactg
     7801 aaaaacaaac ggaaatctca aagagaatac tttgccattc agaaaaaaga catcatctta
     7861 tttgggctgt aacaggtgca gggaaaacag agatgcttta tcctatttta gtggaaactt
     7921 taaaagctgg aggaagagta gcgatttgta caccgcgagt cgatgtttgt aatgaattgt
     7981 ttttacgcta tcgttatgtt tttccagaag aaaaaatcac gttgctccat gggaatacag
     8041 caacggctta tacctttact tcttttgtta tctgtacgat tcatcagcta taccgttttt
     8101 atcggtcctt tgatttaata gtgatcgatg agatcgatgc gtttccttat aacggggatg
     8161 caggattagc tcatgctgtg caaacagcga ttaaaccaga cggacgattc atctacttaa
     8221 gtgccacacc tgataaaaag ttactaaagg agatcaagca gacgtttgac atccacaaac
     8281 ttgctttacg ctttcatcgg cgtttgcttc ctgaacccgt cttggttttc atgaataatt
     8341 ggcgacaaaa atgcaagaac aagaagaaga taaaatcttt ggtgcggatc attcatcaat
     8401 taattaaaga aaaccatatc cttttatttt gtccaagtat cacgatgatg catcgtttga
     8461 aagccacact tcaagaggct cttccgagat atgagatcac agatgtttct tcaagagaca
     8521 atcagcgggc ggaaaaagtc cagaaaatgc gagaagcaaa atatgacata ctgttaacca
     8581 cgatgatcct tgaacgtgga gtcacatttg aaagaatatc cgttatcgtt ttaggagcgg
     8641 atcatccggt ttttactaaa tcttctttgg tacaaatcgc aggaagagcc gatcgtaaag
     8701 ggccttatac gaacagtcaa gtatattttt tctatgaaga aaaaactgca gctattcgaa
     8761 aagcttgtca ggaaatcaaa gaaatgaatg aagaagggaa gaagatactg tgaggtgcag
     8821 ttgctgcagt aaagatatcg tccaaaattt aacattcagc gagattattg gtgtttcgaa
     8881 atacagatta cctcagactt gttcagtttg tcgcgcacaa tttcatttat tggaaacaag
     8941 aggctgttct ggctgtcaaa aaccaatcca tttcaatcta gagagtacga aaaagaaagt
     9001 aaattctatc cccgtttact gcagtgactg tcaagaatgg aagaagaaat atccgaccta
     9061 tgattttcag caccgtgcct tttttgtgta cgatgaaaat atgaaggcct ggctcaatca
     9121 atacaagttt atgggagata tccgactagc aggcaccttt gcatataaat ggacgcagat
     9181 aaaaaaagaa tacccgacat acatctattg tccaatacct ttatctgaaa aaaggcgaac
     9241 agaaagagga ttcaatcaag taagcgagat gttgaaagca gcaagaattc cttttcagat
     9301 gctactcaaa agagagaagc atctgctggc tcaagcaaaa aacacgcgaa aggaaagatt
     9361 ggagatgcct caaccttttg aacttgcagt caccttttct aagatacaaa ataaaaaaat
     9421 attgattatt gatgatgtct atacaacagg acagactctt ttccacgcag cagattgttt
     9481 gcagatcgca cagccgaaaa tcatccgaac tatttctttg gcgagatgaa ttagatgtgg
     9541 aaatttgata gcgatttaat ttgcaaataa cctagagttc gatataatag aattaagaag
     9601 agggaaagag tggtccttct ccttcttgat tgtggtagac gaaaggggta atttttatgt
     9661 ttagatataa tgtacgcggc gaaaatatcg aagtaactga agcgattcgc gactacgttg
     9721 agaaaaaagt aggcaaacta gaacgctatt tcagtgacgc acccgatgca acggcgcatg
     9781 tgaacttaaa agtttataca gaaaaaacag caaaagtgga agtaacgatc ccattacctt
     9841 atcttgtatt acgtgccgaa gaaacttctc cagatttata cgcaagtatc gatttggttg
     9901 ttgacaaatt ggaacgccaa atccgcaaat tcaaaacaaa aattaatcgt aaatcccgtg
     9961 aaacgggcat gaatactgca aatgctgctg ctttattcaa tgaagaggac gaaaacgaaa
    10021 atgattctga attagatatc gtacgtacga aacgcctttc attgaaacca atggatagtg
    10081 aagaagcagt cttgcaaatg aacatgctgg gacataactt ctttattttt gaagatgcag
    10141 aaacaaatgg tacaagtatc gtttaccgcc gtaaagatgg aaaatacgga ctgattgaaa
    10201 cagactgatc agccttactt aaataacaac gaaaacttgc agcagctact gacagctgcc
    10261 gcaagttttt ttgagtttcc tcctctttta gatgaaatat gaataaatta tgaagttctt
    10321 actttaatac gcttaagata tttcaattat ctataactaa tgataaaatg aaaagtaaag
    10381 tctacatagt ctggataata cacagaagga aaaggagatt acacaacgca tggccaattt
    10441 gattcgttca cttatcgaaa acgataagaa agaactaaaa cgtttagata gcattgcaaa
    10501 aaaagttgaa gcatacgctg accaaatggc agcattaact gatgaacaat tacaggcaaa
    10561 aactgctgaa ttcaagggca gataccaaaa aggagaaaca ttagatcaat tacttccgga
    10621 agcttttgca gtcgtccgag aagcagcaaa acgtgtatta ggtttatatc cataccacgt
    10681 acaattgatg ggtggaatcg tgcttcacga tggaaatatc cctgaaatgc gtactggtga
    10741 aggtaaaacc ttgaccgcaa cgatgccagt atatctaaat gctctgactg gcgaaggggt
    10801 acacgtagtt accgtcaatg aatatttagc aacccgtgac tcgacggaaa tgggcgaact
    10861 ttataatttc ttaggattaa cagtggggtt gaatatcaac tcaaaatctt cggatgaaaa
    10921 acgcgaggct tataattgtg atatcactta tagtacgaat aatgaattag gatttgacta
    10981 cttgagagac aatatggtcg tttaccgcca tcaaatggta caacgtccgc tgaattatgc
    11041 cattgtcgat gaagttgact caatcttgat tgatgaagcg agaacgccgc tgatcatttc
    11101 agggcaagca gaaaaatcca cagctttata tacaagagca gacaacttcg tgaaacgttt
    11161 gaaagaagaa gaagattata aaatcgatgt acaatcaaaa acaatcagtt taaccgaagc
    11221 agggatcgaa aaagcagaag aaacattcgg tttggataac ttatacgaca ttgaaaatac
    11281 tgcattgacc catcacttgg atcaagcatt gagagccaac tatatcatgc ttttagatat
    11341 cgattatgtt gtccaagacg gaaaagtact gattgttgac cagttcactg gtcggatcat
    11401 ggatggacgc cgttattcag atggacttca ccaagcaatc gaagctaaag aaggcgtaga
    11461 gatcgaagac gaaacgaaaa ccatggcgac gatcactttc cagaactatt tccgtatgta
    11521 caagaaactt gcgggaatga ctggtacagc taaaacagaa gaagaagaat tcagagaaat
    11581 ttataacatc caagtatacc agattccgac aaatcgtccg gttatccgtg atgatcgtcc
    11641 agatttgctt tacccaacat tacaaagcaa gttccacgct gtcgtgcaag atatcaaaga
    11701 tcgctaccgc aaaggtcaac ctgtgttagt cggaactgtt gcggttgaaa catctgagtt
    11761 attatcagat atgctgaatc aagaacgtat tcctcatgaa gtgctgaatg cgaaaaatca
    11821 ctttaaagaa gcagagatca tcatgaatgc tggtcaaaaa ggtgctgtga cgattgctac
    11881 caacatggct ggtcggggaa cagatatcaa gttaggactt ggggtaagag aacttggtgg
    11941 tctagcagtt atcgggacag aacgacatga atctcgtcgt atcgataacc agcttcgagg
    12001 acgtgcagga cgtcaaggag accctggtat gtcacagttc tacttgtcat tggaagatga
    12061 tttgatgaaa cgattcggtt cagaacgaat caaagctttc ttagatcgga tgaagatcgg
    12121 tgaggaagat gctgttatcc aaagcaagat gctgacgaaa caagtagaat ctgcacaaaa
    12181 acgtgtagaa ggaaataact atgacacacg taaaaacgtc ttacaatacg atgatgtgat
    12241 gcgtgaacaa cgtgaagtaa tctataaaca gcgacaagaa gtaatcatgg aagaaaaaag
    12301 cttatccaag ccactaatga acatggtcaa acggacaatc agtcgtgtag tagatgcgca
    12361 tacacaatta gagaaagaaa attggaattt ggaaagtatc atcgattttg ccggcagtac
    12421 tcttgtccat gaagatagta ttactcttgc agatatcgaa ggaaaaacag ctcaggagat
    12481 caaagagtat ctaaacgaac gagcacaaga agtatttaat accaaagcgg ctcaactaaa
    12541 tggtccagag caactgttgg aatttgaaaa agtcgtgatc ttgcgtgttg tggactctaa
    12601 atggacagac catattgacg caatggatca attacgtcag tcaatcggct tacgtgctta
    12661 tggacagaac aatccattag tcgaatatca aacagaaggc tataagatgt ttgaagatat
    12721 ggtaggcgcc atcgagtatg aagtcactcg aatctttatg aaagctgaga tccgtcaaaa
    12781 cgtacagcgt gaacaggttt ctcaaggaac agcttctcac tcagaagacg gagatgccaa
    12841 agaaaatagt aatactagcg cgaaaaaaca gccaatccat gtgaacaagg tcggaagaaa
    12901 tgatccttgt ccttgtggaa gcgggaaaaa atataagaac tgtcatggaa aaaatgcaaa
    12961 ctaatttctg acagcaggat tggtgagaca aattcttttt ttaagaattc gtctcacctt
    13021 ctttctgtta tttgctgatt ctgttagact agatataatg aaaaaagtat agtgaaagaa
    13081 ggaaaaaaca tggaaatatc cgaaattcga aatctcctga cagaaatgca ggaaaaggtc
    13141 acaagtttca ggaggtctct ttgacttaga tcagctggaa gaagacatcg cggaagcaga
    13201 agcaaaaatg gctgaacctg gtttttggga tgacagcgaa gccgcacaaa aagtgatcag
    13261 tgaaaataac gctaataaag aaacctatga ccaattccat tctcttgccg aagaactaga
    13321 agaaatcgaa ttgatggtgg agatgctgca agaagaacct gatgcagcaa tgcaagaaga
    13381 agcagaaaca cgtatcaatg cattagatga aaaaatgaag acgtatgaat tatctatgct
    13441 gttagacgga ccttatgatc gaaacaatgc gatcgtcgaa ttgcatccag gggctggcgg
    13501 aacggagtcc caagactggg gcagcatgct tttacgtatg tatacacgtt gggcagagca
    13561 gcatggctat caagtagaaa cactagatta tcaagcaggt gatgaagcag ggatcaagag
    13621 tgtgaccctg ctgattaaag gacataacgc ttttggttat ctaaaatcag aaaaaggtgt
    13681 tcatcgcctt gtacggattt cgccttttga ctcagcgaaa cgacgtcata cttctttttg
    13741 ttcggtagat gtgatgccag agcttgatga aacgatcgat atagaaatca atccagatga
    13801 tttgaaaatc gatacgtacc gagcaagtgg tgcaggtggt cagcacatca ataaaacaga
    13861 atctgctgta cggatcactc acttgcctac aggaacagta gtagctagtc aggcacaacg
    13921 ctcacaattg aaaaaccgtg agcaagcgat ggggatgtta aaagctaagc tttatcaatt
    13981 agaagtggaa aagaaagaac aagaagcagc tgcacttcga ggagaacaaa aagaaatcgg
    14041 ctggggttca cagatccgtt cttatgtttt ccatccctat tctatggtaa aagaccatcg
    14101 gacaaacgta gagacaggaa atgtccaagc agttatggac ggtgaccttg atttatttat
    14161 tgacggctat ttaaaaatgc atctacaata agaacccatt gttaaattga aataaaattg
    14221 taagattttg caagcatgtt gaaacattgc catgctataa tagctaaaga ctgaaaaaga
    14281 tatggagaga acgccatgat tgaaatgaag gatgtaatga agaagtactc aaatggtacg
    14341 accgctatcc gcaatctctc gattgtcatc gaacaaggag agtttgtcta tgtggttggt
    14401 ccgtctggag ccggtaaatc tacattcatc aaattgatgt atcgagaaga aaaagcttca
    14461 aaaggaactt tgaacgtcgc aggtcatgat ctaatagcaa tcaaaaaccg cgaagttcct
    14521 tatctacgca gagaaatcgg cgtggtgttc caagactata aattattacc aagaaaaaca
    14581 gtatatgaaa atgttgcgta cgctatgcaa gttatcggca gaaaacctcg agatatcaaa
    14641 aaacgagtaa tggaagtgct ggaccttgtt ggtttgaaac acaaagttcg agtctttcct
    14701 agcgaattat ccggtgggga acagcaacgt gtctctattg ctcgggcaat cgtgaatacg
    14761 cctaaagtac ttatcgcgga tgaaccgaca ggaaatctgg atccagaaaa ctcatgggaa
    14821 atcatgaaat tattagatcg gatcaatgcc caaggaacta ctgtcgtgat ggctacacat
    14881 aacagtacga tcgtaaatac gattcggcac cgagtaattg ctatcgaaaa cggccgcatt
    14941 attcgagatc aagcggaagg ggaatatgga tacgatgatt agaacctttt tccgccattt
    15001 attagaaagt atcaagagtt tgaaacgtaa cggctggatg acagttgctt cagtcagtgc
    15061 ggtaacgatc acgttgactt tagtcggtgt attcatggca gttatcatga atgcaactaa
    15121 attagctcag gatatagaag gaaacgttga tgtatctgta ttcgtagata tcggtacaaa
    15181 agacgaagag atgaaaaagc tagaaaaaga attgaatgac ttagatcatg ttaaaaaagt
    15241 tgaattttca agtaaagaac aggaattgaa aaaaatccaa aacgaaatgg gtgattcctg
    15301 gaaattgttt gaaggtgaca ataacccgtt atatgatgtg tatgtagtaa gtgctactga
    15361 tccttcttat acaaaacaag tagcagaaga agcagcagat ttgaagaatg tttctcgttc
    15421 tgattacggt ggagcttcct cagatcggat tttccaaatc gctggtgcag ttcggacatg
    15481 gggattagtt gcagcggcat tgctgctgtt cgtagcgatg tttctcattt cgaacacgat
    15541 tcggatcacg attttgtcta gacagcgtga aattcaaatc atgcgtttag tcggtgcaaa
    15601 aaatggatat attcgctggc cgtttttcct tgaaggtggc tggatcggtc tgatcggtgc
    15661 gattcttccg attttgatca tcacatttgg ttatgcatgg tttttccaat tgatcaatcc
    15721 atcattatta cgttcccatt attcattgat tcatccacaa aatatcgttt ggaaaatcaa
    15781 tcttttaatg gtcggcattg gtgtgatcat tggttcactt ggctcgatca tttctatgag
    15841 acgtttcttg aaattctaat accacaatat aaataaaatg agaaagttgg acagtttcgt
    15901 tccagctttc tttttttatt ggctaggaga atagaaggaa gcggcttttt tccctttact
    15961 ttaaaaaaca acttgggtat tcttaagttg gtagaggaag aggtgaagcc gtgaaaatta
    16021 tcgttgacaa tttttttacg atccttttga ttatgaatat tttgctttcc tttatcatcg
    16081 tttttcgaga aagaaaggaa actgctcaaa catgggcatg gctgctcgtt ttgatgttca
    16141 ttccagttgt aggatttatt ttatatattt ttttaggaag agggatttcc aaagagaaaa
    16201 tctttgattt gaagatccaa gggaaaatcg gtaagaacct ggaaattgaa gaagacaaac
    16261 aggcattgat gcgagggctt tatcctcatc cgcctactgg acaagtagat gtgaaacaat
    16321 tgatctatat gctcacggta tttgaaagta cgctctatac gactaaaaat gaaatcactt
    16381 tatttacaga tggtcgtgaa aaattcgatg cgctgattga agatatcaag caagcagaag
    16441 accatatcca cttccagtat tatatttatc gcagtgatgc attaggtgaa gaagttcgag
    16501 atgcattgac agaggcggca agacgagggg taaaagtcag agtccttctt gatgcatggg
    16561 gttccacaca agtttcttcc agcttttttc agaatttgaa aaaagcaggc ggagaaatcg
    16621 catttttctt tcctctattt gttccgtata ttaatcctcg gatcaattat cgcaatcatc
    16681 gtaaaatcgt agttattgat gggaaaatcg gatatacagg tgggttcaat gttggaaatg
    16741 aatatctagg attggtaaag aaatttggtt attggcgaga caatcatttg cgtatttacg
    16801 gagaagcggt gtatatcttg caaaaccgtt ttttgatgga ctggaattct cagcatacaa
    16861 aagaagtagg ctattctccc aaattttttc cgtccattca ctctactggt gatatagctg
    16921 ttcaaatcgt gacaagcgga ccagataccg aacatgaaca aatcaaaatg acttatttga
    16981 aaatgatttc gttagccaaa cgggagatat tgatccaaac gccttattac ataccggatg
    17041 gatcgattca tgaagcactg aagttggctc ttctttcagg cgtaaaagtt catatccaaa
    17101 tacctaacaa accagatcat cttctcgttt actgggcaac gtattctttc gctgcagagc
    17161 tgatcgagta tggagcaagg atcgaaacat atgagaatgg atttattcat gcaaagacga
    17221 tgattatcga tggtggcatt gtttcagttg gctcagcaaa tatcgatgtt cgttcatttc
    17281 gcttggactt tgaggtcaat acactgattt atgatgaacg aatggcttca cgtgtaagaa
    17341 aagcattttt tgaagactcg aaaatttcta cgcatctcac aaaagaaatg tatgaaaacc
    17401 gaggaataat catcaagatg aaagaaggat tagcaagatt gatttcgccg ctcctttaaa
    17461 acacaaaaag gacatgagaa ccatcaacag atggagatct cgtgtccttt tctaacgggg
    17521 ccatttctga gagtacgtca gaaatggaga aagcgtctcg catgagcgaa attaactttg
    17581 gggtatctct tgttttttgg ggaaagcaag aaataagcta atatatgcta ttaaaagaga
    17641 cacatttcaa agccagtata gcatagaaac ttttaatgag atagtttttt ttacaattat
    17701 gaggatttat tttgttattt aatgattttg attcgttttc atcaagtaat gaaaatgata
    17761 aaataaacat actttaggat taaaggagat ttctaatgaa aaaacttaaa ttattcttac
    17821 caataatagg attagctatt cttttatcag gctgttcaaa gtggattgat cgaggagaat
    17881 ccattacggc tgttggctct tctgctttac agcctttagt agaaacagtt gctgaaactt
    17941 accagacaga aaatcctgga aaattcatca atgtacaagg gggcggaagc ggaactggtt
    18001 tgtctcaagt acagtcagga gcagtcgaca tcggaaactc tgatttgttt gcggaagaaa
    18061 aatcggggat cgatgcctca gcattagtcg atcatcgagt agcagttgtt gggatcactc
    18121 ctattgtgaa caaggatatt ggcgtaaaag acatcagtat ggaaaacctg aaaaaactat
    18181 ttacaggcga gatcaaaaac tggagtgaag tcggtggaaa agatcagcca gtagttatat
    18241 tgaaccgtgc ttcaggaagc ggaacccgta gcacgtttga aaaatgggta ttggacggag
    18301 aaacagctgt tcaggcacaa gaacaagatt caagcggaat ggtgcgccag atcgttgccg
    18361 acacacccgg tgcaatcagc tatgttgctt tttcttatgt ttccgatgat gtagatacgt
    18421 tgaatgttaa cggtgtagaa ccgacagatg aaaatgtgac aacgaacaaa tggacgattt
    18481 gggcatatga gcatatgtac acaagagatc atccaaaaaa actgacaaaa gaatttttag
    18541 actatatctt atctgatgaa gtacaagata acatcgttgg agaactaggt tatatccctg
    18601 tttctcatat gaaagtcgaa cgtgattggc aaggaaatat cgttaaagag taatctttac
    18661 acaaaattta caaacttagc taaactttta catgttatta aaaccaaatt gatgttcaat
    18721 ttgtacactg agtgagtatg ttaaacctga ttaaggggga gtcatctgtg gaagatgtga
    18781 aaaaagtatt attaacaaaa tcaaaacgtt caaaaatgga acagcgtgga aaattcatca
    18841 gttttttatg tatcgcgctg atcgtgttgg ttgtattatc tattttttat tttgtagcta
    18901 gtaaaggatt ggccaccttt tttactgata agatcaatgt atttgatttt ctgtttggta
    18961 cagattggaa tccaagccaa atcggagcaa atgggaaacc aatggtaggg gcattgccta
    19021 tgatcacagg ttcgtttatt gtgacctttt tatctgctat tgttgccaca ccatttgcca
    19081 ttggtgcagc agtattcatg acggagatct ctcctaaaaa cggaacgaag atcttacagc
    19141 cggtcatcga gctgcttgta ggtattcctt ctgtcgttta tggttttatc ggtttatcag
    19201 ttatcgtgcc ttttgtcaga agtatttttg gcgggacagg gtttggtatc ttagctggta
    19261 catttgtgtt gttcgttatg atcttgccga ctgtcacaac gatgactgtt gatgcattaa
    19321 aggcagtacc acggcactat cgggaagctt cattagcgct tggtgccaca agatggcaaa
    19381 caatctacaa agtcgtgcta cgagcagccg tgcccgggat tttaacagca gtcgtttttg
    19441 gtatggctcg tgcgtttggt gaagccttag ctatccaaat ggtcatcggt aatgcagcat
    19501 tgatgccaac aggacttact actcctgctt ctacattgac gtccatctta acaatgggaa
    19561 tcggaaatac aatcatggga acagttgaaa ataatgtgtt atggtcatta gcgctgatct
    19621 tgctattgat gtcattattc tttaatatcg tgatccgtat gattgggaag aaaggagagc
    19681 tgaaataatg aacgcaaaac gctcagataa aattgctaca ggtgttttat atgtagtttc
    19741 ggggatcatc gtattgattt tagcagcttt actactttat atcttagttc ggggaatacc
    19801 gcacatttca tggtccttct tgaccgaacc ttccaaagcc taccaagaag gcggtggaat
    19861 cgggatccag ctatttaact cgatttattt gcttttgatc acgatgatca tcagttttcc
    19921 tatttcttta ggtgcgggta tctatctttc agaatatgct ggaaaaaact ggctgacaga
    19981 tgtgattcgc acgtcgattg aaatcttgag ctcattgcct tctgtcgttg tcggtttatt
    20041 cggtttcttg gttttcgtta ttcaattcca gtatggtttc tcgattattt ctggtgcatt
    20101 ggctttgact gtattcaact tgcctctttt gactagaaca gttgaggagt ctttacaagc
    20161 ggtccattac acacaacgag aagcaggatt ggctttaggt ttgtcacgct gggaaacagt
    20221 gataaaagtg gtggtttcag aagcgacacc agggattttg actggtgtga tcctaagttc
    20281 tggaagaatt tttggtgaag cagctgcatt gatctatacg gctggacaaa gtgcacctgc
    20341 gttagatttt acgaactgga atccattaag tgtttcaagc ccgatcagca ttttccgtca
    20401 agctgaaaca ttagctgtcc atatttggaa gatcaataca gaaggcacga tgcctgatgg
    20461 tgtttctgtt tcggctggcg cttctgccgt gttgatcatt gctgttttac tgttcaactt
    20521 cggcgctcgt gcgattggca aacgattata ccgaaaaatg acttcagcct aaggagaaga
    20581 agcaaaatga aaaaatataa ctggaatgaa acaaatgtca tcaccatgcc aaaagagaaa
    20641 gaagtagcac tatatacgga tgatctacat gtctggtatg gcgacaatga agcaatcaaa
    20701 ggagtggatc tggaatttga aaaaaataag atcactgcac tgattggtcc ttccggctgc
    20761 ggaaaatcta cgtatcttcg ttcgttgaat cgaatgaatg atgggatcgc taatacgaaa
    20821 atcactggga aaatcatgta tcaaggcgta gatattaatg cgcctcaagt ggatgtttat
    20881 gagatgcgca aacggattgg catggttttt caacgtccta atccgttcag caagtcgatt
    20941 tatgacaata ttacatttgc tttgaaacag cacggcgaaa aaaacaaaaa gaaattagat
    21001 gaaatcgttg aaacaagctt gaaacaagct gccttgtggg accaagtaaa agacagcttg
    21061 gacaaaagtg ccttggcttt atctggcggg caacagcaac gtttatgtat tgctcgtgcg
    21121 atcgcgatga aacctgatat cttgctgcta gacgagccgg caagtgcttt ggaccctatt
    21181 tcgacaggaa cggttgaaga aacacttgta aacttgaaag aagactatac gatcatcatc
    21241 gtgacgcata acatgcaaca agcggctcgt atcagcgact atactgcctt tttctatcta
    21301 ggaaaagtaa tggaatatga caaaactaac aagatattta ccagaccaaa aattcaggca
    21361 accgaagatt atgtgtccgg tcattttggt taagacggag gcctcaacat gacaaaagaa
    21421 attatttcat ctaaagatct tcatctgtat tatggaaaga aagaagcact aaaagggatc
    21481 gatctaagtt tcaatcaagg ggaaatcact gcgatgatcg gtccttctgg ttgcgggaaa
    21541 tccacttatc tgcgttcttt gaaccggatg aatgacctga ttccgaatgt aacgatcacc
    21601 gggagtgttt tatataaaga caaagacatc tatggtccaa aaacagatgt tgttgaacta
    21661 agaaaagaaa tcggcatggt attccagcag ccaaacccat ttcctttttc tatctatgaa
    21721 aatgtcatct atggattgaa attaaaaggg gaaaaaaata aaaaagtcct tgatcaagta
    21781 gttgaagaaa gcctgaaggc agcgtctgtt tgggatgatg tgaaagacaa attgcataaa
    21841 agtgctttat ctttatccgg tgggcagcag cagcgtgtat gtatcgcacg tgttttggca
    21901 gttaatccgg aaatcatctt attggatgaa ccaacaagtg cgcttgatcc tgtttctact
    21961 gggaaaatcg aaagtatgct gttagaatta agagagcggt atacgatgat catcgtgacc
    22021 cataatatgt ctcaagcttc acgtatttca gataagacgg cattcttttt agatggtcac
    22081 ttgatcgaat acaatgatac gaagaagata ttcatgaatc cagaaaaaca agagacagaa
    22141 gattatattt caggtcgatt tggataagga ggaaacggaa tgctacgtac acaatttgaa
    22201 gaagaattgc tgaatctcca taatcagttc tacgaaatgg ggatgatggt gagcagcgcc
    22261 gtgcacaagt cagttcgtgc atacatcaaa cacgataaaa tcttagccca agaagttatc
    22321 gaaaacgata taaatatcaa taacatggaa acacgcttgg agaagaaaag ttttgaaatg
    22381 atcgcattgc aacagccagt tacaactgat ttgcgtatga tcattacggt catgaaagct
    22441 agctcggatt tagaacgtat ggccgatcat gcggtgtctg ttgctaaatc cacgattcgc
    22501 gtaaaagggc agacgagaat accggaaatc gaaaaagaga tctccgatat gtccgattat
    22561 gtgaaaaaaa tggtggacaa cgtcctagtt gcttatgtca aaacagacga aaaagacgca
    22621 cgtacgatcg ccaatatgga tcaaagagtc aatgactatt tcaatcgaat ctataatgca
    22681 acaatcaaaa atatgcagga aaatcctgag acagtcatca gtggaacaga ctacttgaat
    22741 gttgccagtt atctagaacg gatcggagac tatgtgacaa acatctgtga atggatcgtc
    22801 tacttggcta cagggaaaat cactgagtta aatacgaacc acaatgagat tttctaaact
    22861 aaagcggtga ttctgccgtt tgtttaggaa aagaggttgt gaaatcagcg gttgtgaaaa
    22921 agctgttctg catcaagtaa taagaacagt caaacaaaaa tagctcctca tatttttcat
    22981 ttggctggac ttattaccgc agatgcaagc ttttgaacac tgtttattcg ggaaagggtt
    23041 tgtgacaaaa tatgtcacaa acccttttca tcatttcata gaaaggataa agaatgcaaa
    23101 aaaaaattag catcatcact atatttttta tttgtgtgct tacttcatgg gttattcagc
    23161 atcaagctgc tttatatgaa gtacctgtca tcgagatcga aaaagtacga ataaaagagg
    23221 atcatcaatt gattacagga agactgatga acacgaatca aaaaggagaa tcgatttatt
    23281 tatcggttcc ttatcaaaaa aatcaaatag aaacagcaaa tataaaagcg agacaaatgt
    23341 atctagtcca aatgcatgga gatgaatggc agctagtagc aaaaaaaaat gatggctggc
    23401 ttttcttctt cacaagtatc ttcattggcg ccatgttgct tattggcgga aaacatggtc
    23461 tatttgcttt aggaagtctc atcatcaata tcgttttact tttacttttg ttgctcatct
    23521 ttactaaaat agaagggatt tctctattaa atatatctat cctgttcgtc gttataggga
    23581 tgattattag catattggct ttagatggat ggaatagaag cagtataatc aaaatttcag
    23641 ctgcagttac gagtgttttt ttagcatttt ttatttgtct tttgacaatg aatctttgga
    23701 aagaccaagg actgcgctat gaggaactga attatctgac acgaccgtat cgttctgttt
    23761 ttctttctag cgtactgatt ggaacagctg gaggaacact cgataccgtt atcacagtca
    23821 ttgcgacatt agaagaattg actaagcgac aaccagaaat aacagcgaaa cagttatggc
    23881 tttcgggaag gcaagtgggt cgagatgtga ttggctcgat gaccaatatc cttttgttcg
    23941 tctatatcag tgggtcagtt ccatcgcttc ttttatattt aggaaatcaa tggtcgttca
    24001 aagaaacgat agaacagcat ttatcattgg aatttttacg cgtcattgct ggcagcttag
    24061 gaatagtatt atcgatccct atctcggtcc tcttttttct gactgtaagg aggctgaaac
    24121 gatgaatgta cttattatac ttgttgggat tttagcaatc agcgtgctac ttattggcgg
    24181 tacgcaaggt atgtatattc ttttaggctt attcatcaat ttagggatct ttttcttgtt
    24241 gttattcggt tatcatcaga agtggccgat actggcattg tcggtcatag gatttttatt
    24301 gattgctgtg gttatcttat tttttatcaa cggttataat ctaaaaatgc gtgcagcttt
    24361 tgtgagtata ctgatctttt tattttgttt cctactattg cttcctatca ctgatttttt
    24421 agcaatccaa ggttttacaa cgatagaact agaagaatta tctggcttag ataagacttt
    24481 agcgattgat tttagattac ttacgagatc gttgcttctg attagtctta gtggtgctgt
    24541 tttagatgcg agtgtagcaa tttctagtgg gacattcgaa gtatatcagg caaatccgca
    24601 attatctttt taccaattgc gccattctag tttcgctatt gctaaaaaaa tattggcgtc
    24661 aacagtaatg acacttcttt ttgcattcat gggaagttct ttagcgttga tcctctggtt
    24721 tattgattta gacattcctt ttcagcaagt gatcaatgaa aaatcatttg ttctagaata
    24781 tacgatggct attcttacca cattgtccgc actacttgtt cttcctttaa cctgcgtgac
    24841 tacagcatat ctctttacaa aaaagaaaga acaactcaag atggagtaaa agttacaact
    24901 taagtcctat gacattttta ctgaatcagt gcataatatg gatgtaagga aaagcttgca
    24961 aacaattttg cttaaggagg caatttccat gaaagaaaga gaacgtattt tagatttagt
    25021 gaaaaaagga atcctttcga ctgaagaagg cttagattta ttagaaagca tggcaactga
    25081 aaaagacgaa aagcaaatca aaaaagaagc agacaaggta actgctagtc ataaagaaaa
    25141 agatcaggca agtcaattga tcgataaact tgaaaacggc gaagaagaaa tttctgagcc
    25201 agttgatcca aaggaaagag aaagacaaga tcaagaaaac ttagaaaaga tcttagatga
    25261 actagcaact gaagcgaata aaacttcggc gcgtctagat gaagtaaatg ctcaattcgc
    25321 tgacaataag gcagcacgca atgagaaaca ggaagcattg atgcagctga atacaaaaga
    25381 agaattaggc gagttgacag aagaagaatt agcacagcgt cagacgttag aagcagaaat
    25441 caaagagtta gaagctagtg gcgatacact gttagaagaa caattgaaat tagaagcaga
    25501 attaaaagat atccgtaaga atcaatggtc tgagaaaaaa gaaacgttta ctgataagtt
    25561 tgaattgcca gatgattgga aagatcaagc aacagataca ctgaatcaag taggcgaaaa
    25621 aatgtcagaa gctggatcac agttaggaaa attcttgaag aaaacattcc aaactgtttc
    25681 agaaacagtg aatgacaaca tggaatggaa agatgtcagc ttgcgtgttc ctgggattgc
    25741 gacaacgaaa tttgagcatg aattttacta tgaagctcct gcagcaagta tccttgatat
    25801 caaggcagca aacggaaacg tgacgttaaa aacgtgggac agcaacgatg tgaaagttga
    25861 agctaagatc aaactttacg gaaaaatggg tgctgaacca tttgaagcat tctctgaacg
    25921 gagccagatt gaggttaatg aagatcatat ctccttccaa attccaaata aacgtgtgcg
    25981 tgcagacctt gttttctact tacctaaacg agtatacgac cacgcagcta ttaaacttct
    26041 aaatggcaac atcatgattg aaacattgga agctaaagat atttatacaa aatctacgaa
    26101 tggtaacatc atcgtggacc aattaactgc aacgatgctg gaagtagaag gtgtaaacgg
    26161 caatatcgat attcgaaacg ggaacatctt agattctatt atcgaaacag taaatggtac
    26221 agtgacattt ggtgcgacag cagaaaacct ttctgtgtct ttggtaaatg gtgatgtacg
    26281 tcttacgatt aaagaagata atttgaaaaa agtagaagca agttcagtga acggaaatgt
    26341 caaagtcgct ttaccagatg gcatcggttt ggaaggacat gctaaaacaa gtcttggaag
    26401 tatcaacagc cgtctgtcca attacgaagt agttcgtgag aaaaaagaac ggacaaacca
    26461 aatgttgcaa ttccgtcgtg tttcagatgg tgaaatcgcg caagtgcaac tttcaacgac
    26521 aacaggaagt atctatttaa aagatacaga taaataaaga ggttgtgaaa gagatgttca
    26581 gccttgagca ataagaagcg attttgtaaa atagcttccc ctattttaca aaattgtgcc
    26641 ttattgccga taggctatct cttgaacacc gtttaccaag agattatgaa cttgccaatt
    26701 atcgccgagt cacaaggaat aatttcaaaa aaagctcgtc acgttttatg aatatggtaa
    26761 tttgtgaccg agaattttgc aaaaagacac cgattaagaa gaaggttgtc acaacgattt
    26821 tcttcattta aaatagtaga acagaggtga gacatgatga aaaaaaagtt gacaaaatcc
    26881 aataaaaatg ttgttttgac agggacttta gcaggaatag gagaatacat cgggattgat
    26941 ccgactgtta tccgtgtgct ttatgtattc ctgagcttag ttgcttttgg aagtccaatc
    27001 attttataca ttttattagc tttgattatc ccatctgcgc gttctgcacg aacaaactat
    27061 ggacataaca atgcatatta tgaaaaaaac aattatcgtg aacaaactcg tgaacaaaca
    27121 aaaaaacgca aagaagcgga aaaaatcgat gatgacgaat ggagtgactt ttaatgtcgt
    27181 actttcaacg tattttagtt aatacgttaa cattcatatc attggctgtt ctttttcctg
    27241 cgatggtcca tgtgagcagt atttggacgg ccgttcttgc cagcttcgta ttgtctgtgt
    27301 tgaatatgtt tgtcaaaccg attttgacga tactgtccct gccctttaca ttagtcacat
    27361 tgggattgtt tacgtttgtt atcaatgcag cgattcttaa aatgacctcc ttttttgtgg
    27421 gagcagaaca ttttagtttt tcttcattcg gtgcagcgtt gttagtagct atcttgatgt
    27481 cgcttgtcaa tgtaattgtc agcgaacata acagtagaaa ataaaagaaa gctgtgccga
    27541 actatcggcg cagttttttt atttagaatc aggaatgcgt tttctattac attggtaatt
    27601 aaataaaaac gtttttttta attggtagta cttttggcta gacaatgata aaatgataga
    27661 gaacactcta atagaaatga ggtagcatga atgtcagaag ttgtaaaagt tagccaatta
    27721 gtgaaaaaat tatctttgga aatcgtgaca ggcgacgaga aaagcttaga ccgtgtcatc
    27781 gtaactgggg acatctcacg cccaggacta gagttgactg gttattttaa ttattattcc
    27841 cataatcgtt tacagctatt tggcagtaaa gaaatcagtt ttgcggaacg gatgatccca
    27901 gaagagcgtt tgatcatcat gagaagatta tgtagtgaag atatgcccgc atttattatt
    27961 tcaagaggat taccagctcc agaagaaatg atccaggcag caaatgaaaa tgggatagct
    28021 gtactgcgtt ctcccatctc aacttctcgc ttattaggag aattatccag ttatttagat
    28081 ggtcgccttg cccctcgaac aagtgtccac ggtgttttag tggatgttta cggattaggt
    28141 gtactgattc aaggtgacag tgggatagga aaaagtgaaa cagcgttgga gttgatcaaa
    28201 cgcggtcatc gattgatcgc agacgatcga gtagatgttt atcagcaaga tgaattaacg
    28261 gtgatcggag aaccgcctaa aatcctggaa catctgattg aaatccgagg aatcgggatc
    28321 attgatgtaa tgaatctttt tggtgcgagt gcggtacgtg gctctatgca agtccagttg
    28381 gctgtttatc tggaagcatg ggcaaaagat aagaaatacg accgtctggg ctctgaagac
    28441 acgaccgttg aaatcgcgga agtaggcatt ccacaaataa aaatccctgt caaaacagga
    28501 cgaaacgttg caatcatcat tgaagtagcc gcgatgaatt tccgtgcacg tacaatgggc
    28561 tttgacgcaa cgaaaacatt tgaagaaaga ttaagtcgct tgattgaaga aaactcaggc
    28621 aacgactagc aaggagtgac aatatgttag cacaaatcaa tcgagttgct tttgagcttg
    28681 tagggattcc tatctactgg tatgcattga tcatcgtatc aggtatcatt atcgccatgt
    28741 ggcttagcag cagagaggct gttcgggtag gattaaaagc agatgatgtg acagatttta
    28801 tgttgtgggg attgcctatc tccattattg gcgctcgctt atattatgtt ttatttgatc
    28861 ttccccagta tatagctgat ccaatccaaa tattcaatat ccgttcagga ggcttagcta
    28921 tttatggcgg actgattgca ggcgcgatca cgctgtattt ttttactaaa tatcatttta
    28981 tttctttgtg gactttttta gatatcgctg caccaagtgt attattagca caagcaatcg
    29041 gtcgttgggg aaatttcatg aaccacgaag catatggacc agacacgacg cgaagcttct
    29101 tagaaagtct gcatttaccg caattcatca ttgataatat gtatatcgaa gggatctatc
    29161 gtcaaccaac atttctttat gaatcacttt ggagtttgat tggatttatt ttgcttttgt
    29221 ttttacgaaa gaaaccacac cttttgaaaa aaggtgaagt ccttttatgt tatctaatgt
    29281 ggtatagttt cgggcgtttc tttattgaag gattacgtac agacagtctt tactttttag
    29341 gtgtgatccg tatttctcaa ttattatctg ctgtgttatt tgtcggtaca ttgattctat
    29401 ttatttggcg cagaaaaaaa ggaaatttac cggattatga ccgctcatta ggaaaaaatc
    29461 aacaaattat ctgattttta gagcgttaaa aatgaaaaaa atttcaggag tggtaaaatg
    29521 aattatagag tagcggtttt aggaccaggc tcttggggta ctgctttggc acaagtcctc
    29581 gccgaaaacg gacatgacgt tcggatttgg ggacatcgtg cttcacaagt agaagaaatc
    29641 aacacccaac acacgaatca acgttattta ccagatcatt gtctacccga ttccatccaa
    29701 gcattcacca atatggaaga tgcagtaaaa gacgcagatg cggtgctatt cgtcattcca
    29761 acgaaagcaa tacgttctgt tgcaaaagaa ctagtgccta aattgaatac aaagccagtg
    29821 atcatccatg caagtaaagg attagaacag gggacacata aaaggatctc tgatatcttg
    29881 ttagaggaaa tcccagtaga aaaaagaaaa gctgttgttg ttctttctgg accaagccat
    29941 gcagaagaag tagcgaaaca tgacatcact acgatcacag ctgcaagtac agatgcaaaa
    30001 gcagcaaaat atgtacaaga gctgttcatg aataattatt ttcggatcta taccaatcct
    30061 gatgtgatcg gtgtagagat gggggcagct ttgaaaaata ttattgctat tggtgctggc
    30121 gctattcacg gcttagggtt tggcgataat gcaaaggcag caatcatgac gcgcggatta
    30181 gctgagatca gccgtttagg tgtagcaatg ggtgccaacc cgctgacctt tatcggatta
    30241 agcggagtag gcgatctagt cgttacttgc acaagtgttc attctaggaa ctggcgcgca
    30301 ggcaacttgt taggacaagg gcagccccta gaagaggtgc tagccaatat gggaatggtc
    30361 gttgaaggtg tgaatactac ccaagcagcg atggaactag cccaaataat ggaaatcgaa
    30421 atgcccatca ctcaaacaat ctatgaagtg ctgtatgaac aaaaagaaat caaaacagcc
    30481 gcaaaagaaa tcatgttacg tgatgggaaa aaagaaaatg aattctcatt aacaattttt
    30541 tgaaggagcg aatgtatatg aaagtcaaaa aagcagttat tccagcagca ggattaggaa
    30601 caagattttt accagcaaca aaagctatgg caaaggaaat gttgccaatt gttgataaac
    30661 caacaatcca gttcatcgtt gaagaagcgt tgaaatcagg tatcgaagac atcttgatcg
    30721 ttacaggaaa agctaaacga ccaatcgaag atcactttga ttcaaatatt gaattagaaa
    30781 caaacctaag tgaaaaagga aagaccgaat tattgaaatt agtagaagaa acgacagatg
    30841 tcaacttgca tttcatccgt caatctcatc caaagggttt aggacatgcc gttcttcaag
    30901 caagagcctt tattggaaat gaaccatttg tcgttatgct aggcgatgat ataatggaag
    30961 acgaagtacc attgacacag caattaatcg atgattacga acgtactcat gcttctacga
    31021 tcgccgttat gcaagttcct catgatgaaa cttcaaaata cggaattatc aatccaggag
    31081 aagtattgga agatgggtta tacaatgtca aaaactttgt tgaaaaacca gatccaagca
    31141 aagcaccaag tgatttagct attattggac gttacttatt gactccagaa atttttgatg
    31201 tattgtccga gcaacaacca ggagccggaa atgaaatcca actaactgac gcaatcgata
    31261 cattgaataa aacacaacgc gtatttgccc gtaaattcac aggtaaacgt tacgatgtcg
    31321 gtgacaaatt tggttttatg aaaacaagta ttgaatatgg tctaacacat ccagaagtag
    31381 gtgcaccttt acgtgagtac atcctgtctt taggtaaaac attagaagca gaaggaagca
    31441 agatcgatca taatccaaaa ggaataacag aaatcaaaga agaaaagaaa aaataaccct
    31501 tttttctaac gagcttcagc tgctaattga ataaaaagta gttgaagctc gtttttattt
    31561 gtttaaaaaa cacgaaaatg ctatccttat agaaaagaga gacaagaagg gagtttgatc
    31621 atgtcaggag gagaaattgc aggattgatc gcagcaatcg cctttgcgat acttgtcgtt
    31681 tttatcgttc gtgtgttgtt gcaagtttct aaaactttag aaaaagtaga tcagactgta
    31741 gcagaagcaa atacgacgat cgaaatcgtc acaaaagacg tagatctttt gtctagacaa
    31801 gtagaaggct tactggtcaa aagtaatgaa ctgctcttgg atatcaatgg aaaagtcgca
    31861 acgatcgatc cattgttcac agcagttgct gatttaagtg aaagtgtatc agaacttaat
    31921 cattctagta aaaacatcgc gacgaaagtc ggcggaatcg gtaaaacgac agctaaagcg
    31981 acggttgccg gaaaagtcgg tgggacagcg atgaaatttt ttaaaaacaa aaaacatact
    32041 gaaacgacag gaggaaaata aaaatggcta aaaaaggtgg atttttatta ggtgcagtag
    32101 tcggaggcac agccgcagca atcgccgcgt tattgttagc accaaaatct ggtaaagaac
    32161 ttcgggatga attagctgcc caagcggatg atttgatgga tatggcttca gattacacag
    32221 atatggcgaa agaaaaatcg actgagttaa caggtattgc aaaagaaaaa gcgcaagatc
    32281 tttctcaaca agcaggtgat ctagcaggta gtgtcaaaca aaaagtaagt gaatcagcag
    32341 atgaagcagg aagtgaatct gacgatatct tgttaaatct taaagaacaa tcagctgact
    32401 tatctaatcg tttcaaaaaa acggcagaag atatgaaaaa acctgcagat gaattaggaa
    32461 gtattgctaa agatacttca gaagatatca tgattgatgt aaaagacgct gctggtaaag
    32521 caggagatac tgtcaatgaa ggaatgtcag aagcaaaacc agttgcagat gactcaaaag
    32581 aaatgatgaa aatggcaaaa gaagatgcga aagaagctaa aaaagaaata aaagatacaa
    32641 tgacagattc atctacaaat cactaaaatc acaaatttat agaataaaaa ggtgggagcg
    32701 gactagctct cacctttttt actcttattt ttctaaaaca agtaattctt ttggtgtagt
    32761 cgtgaatggc acacagccat cgcttgtcac atatacacag tcttcgatac gtacccctac
    32821 tttttcagga atatagattc ctggttcaag agagaagcac atcccttctt cgattactaa
    32881 gtcatttcct tctacaaggg aagggaattc gtggacggtt gttccgatcc cgtgacctaa
    32941 acggtgattg aaatattcgc cgtagccata gctgttgatc acgtttcgtg cgatttgatc
    33001 aagttcacct gctgtcacac ctggacggac ggcttcttgt gcggcaagct gtgcttcaag
    33061 agtgatgttg tagatttttt cttggaagtc ggttggtttt tgataagcaa ttgtacgagt
    33121 agcatcactg caatagccat tccaaacaac gccaagatcg aataacacaa gttcattcgg
    33181 tgaaatcttc gtatttcctg gtgtaccatg agggcttgca gcatttgctc ctgcaaggac
    33241 taatgtgtcg aaagacattt gtgaaacacc ttgttttttc aattggtatt caatttctgc
    33301 aatgatcgct tgttcagtca cgccttcttt cactgcttta aagccaatct caaatgcaac
    33361 atcggcccat ttaccagctt cgatcagttt gtctttttcc tctagagttt tgatcagttg
    33421 tagacgttgg atgatggaag ttagatcagt gtaagaatcc gttcccgtca agatatcaga
    33481 gatagcatcg aagcgctcga cagtcaaggc gttcttttca atccctacat tgccaggctg
    33541 accatagcga gcacgaagtt cttttccgat gatctcccaa gggttttcgc tgtctaaata
    33601 gccacggaca tcatacgccc aactactgtt ttgagcatct tcaacttcca aagcaggagt
    33661 gaaaaggaaa ggatcttgtt caagagggat aaaaagagct agtacacgct catgaggatc
    33721 actttcgtat ccggaaaagt aagcgatgtg gccagggtcg ctgatataag ccaattcgac
    33781 ttggtgttgt gccatccatt gacgtagttc attgattttt acgttattca tttggcaacc
    33841 tactttctaa attaattttg tattcaataa ttgtaccact gatttattaa aagaccaacg
    33901 ttctaaaaac tgaaaaaagt aaaaattttc atgaaaacag agataaaacg gttgcaattc
    33961 ttgagattat ttgatattct attttagaaa tgtaagacgt attttcagaa aacatataaa
    34021 atatgaatag gagaacacaa atggaaaagc aaacaatcac tatctatgat gtagcgagag
    34081 aggcaaatgt ttcgatggct actgtttcac gtgtcgtaaa tggcaatcca aacgttaaac
    34141 cagcaacaag aaaaaaagtc ttggaagtta tcgatcgctt ggattatcgt ccaaacgcag
    34201 ttgcgcgtgg cttggcaagt aagaaaacaa caacagttgg tgtaatcatc cctgatgtca
    34261 gcaatatgtt ctttgcttct ttagcacgtg gtatcgatga tgtggcaaca atgtacaaat
    34321 acaatattat cttagcaaat tcagatggca acgaccaaaa agaagtcaat gtattgaata
    34381 acttactggc taagcaagtg gacggcgtga tcttcatggg tcaccatatc acagacgaaa
    34441 tccgtggaga attttcacgt tcaaaaactc ctgttgtatt agctggctct attgatccag
    34501 atgaacaagt aggtagcgta aacattgatt atgtatccgc aacaaaagat gcagtaaaca
    34561 aattggcaaa aagcggcaat aaaaaaatcg cttttgtcag tggtgcgttg atcgatccca
    34621 tcaatggaca aaatcgtctg aaaggctata aagaagcatt aagcgaaaat aacctaccat
    34681 atagcgaagg attgatcttt gaagcacaat acaacttcaa agatggtcta tctctagtcg
    34741 atcggatcca taatagcggt gcaacagctg tctatgtttc agatgatgaa ttagccatcg
    34801 gtattttgga tggtttatta gaccgtggcg tgaaagtacc ggaagaattc gaaatcatca
    34861 caagtaacaa ttcactactg acagaagtag ctcgtcctcg tttaacaagt atcacacaac
    34921 cattatacga tttaggggct gtatctatgc gcctattgac gaaaatgatg aataaagaag
    34981 aagtcgaaga aaaaacgatt atcttgcctt atggaatcga agaaaaagga tctacaaaat
    35041 aataaaagga caaccattca gaggttgtgt gcctgccgtt taactctgcg ttacaaggag
    35101 caatttcaaa aaacagcatc tcatgtttga tgaatattgt gactcgtgat tcggagttgg
    35161 caggagaaca ccgtttattt gggaaaaggg gttatgacaa aattttgtta taatcctttt
    35221 tttgtgtctt aaaaaagaga gaaagtggtt gaaattacat ttatcgtata taaaacaatc
    35281 cgtgtataga tgctgcattt tgttcaccac catcaaaaaa ataagggact gtgacaatac
    35341 tattgtcaca atcccttatt actgtgtatt ctattaaatc aatcatcttt ctcatctgat
    35401 tctttagttg cttgattcgc tcttgcataa gctgaagcgg tgttccagta atctgtatag
    35461 ttttcatcgg taccgccaac gccaaattta aaggcgcttt tcttcggtcc atttttcgcc
    35521 catagcgatt caactgtttt tcctggtgtt tggatggatt ttttattgac agtaactttt
    35581 ccaggtgttt gaccagtaaa tccagatact tttttcttca tcacatcaga tgataattcg
    35641 aatttctcat cagtgccaaa aatgtcaggt tttgcttggt aagcttgatt gatcagattg
    35701 gcaagataat tagccgaacg tatccttgct ttgctgtcca ttccagtatt gtcatcgtgc
    35761 cctgcccagc tactgatggt aatagacgga gtagagacaa ttagccatga atctcggtat
    35821 tcattggtag aaccagtttt tccgacccaa tctgcttttc ctagatttcc gtttaagctt
    35881 gagatggcat ctttgaatgg tgtagtgatt tttgcattga tcacactacg catcatgtca
    35941 ttcatgatcg atgccgttgc ttccgaatag atccggacag agttgctttc gtgtttataa
    36001 attacatttc ctgcgttatc tgtgatggaa tcgatgatat agccttcttc atagacgccg
    36061 ccgtttgcta aagcctgaaa tccgttggtc tgttgaagcg tcgtgacatc tactgtacct
    36121 aaaggagcag attcaacgcc ccaattgtca tttgccgggt agttcatctt tgccaagtag
    36181 tgctcgtaag catattgttt cgatccaccg gaattcaaca catcttgata taagtgataa
    36241 gccgggatat tgttggacca ttctagtgac tcacggacgg tttggaaggt gttcgatcct
    36301 tcgttagtag cattgacgat tttctcgcca gcattttctc cttcttgcca agttgttgca
    36361 taatctgata cacgggattc tgatccgata agccccatgt cgattgcagg tccataaaca
    36421 agaactggtt tgattgatga gccagcttga cgttctgtat cgaaggcatg gttattttga
    36481 ttctgactgt aattccgtcc gccaacgaat ccgtagatgc ggccagttct gttatccatc
    36541 aatacatttc cggtttctac ttgactgcca gcaccatcat ctaacatgta tccataattt
    36601 tcaacgccat tttgcaatgc agcatagaca tctttatcga ttgtcgaatg gattgtatat
    36661 cctttatttt ggatcgtttg ctgtgccttt tgataataag cgtcactgac cgatgaatca
    36721 gacatatcag cgttgtcttt ttcagccaat tgttgtgcaa tgattcttgt tgcttcattc
    36781 atcacagtat aatacaagaa ttctctgtca gtctgttctg cgatttgttg tggtagaaag
    36841 tcttttgtaa ggtcataggc ttttgcttct tcgtattgtt ctttcgtaat ttggccttca
    36901 cgatacatac tgaataaaac aaaatctttt ctggcaaggc cggcagaaag atcttctttt
    36961 agcgcgcctg tgttcgtgta tggactatac gtgatcgggc tttggggtaa tccagcgata
    37021 taagcagctt gcggcagcgt cacatctttt gcatctacac caaagattcc ttttgcagct
    37081 tcctggactc cagcaatgtt ttgtccctta ttattacgac caaatggtga gacattcaaa
    37141 tacgtagcaa tgatctcatc ttttgaaaag tatttttcta cttgtgcaga aagaatgatc
    37201 tcgtttgctt tacgtttgaa tgttgtttca tctgtaagga tctgctgttt gactaattgc
    37261 tgtgtcaaag ttgatccacc agaagagcca ataccagtag cttcagatac taatgctcgt
    37321 aaaacagctt taggaacgta accttggtgt ttatcgaagt attcatcctc tgtgctgata
    37381 attgcagttt tcaataaagg tgaaatctta tcagatgaaa tagtcgtgcg catcagatct
    37441 gtctggattt ttgatatctc tgtattatct gcataaacaa tctttgacgt ttctgtaatg
    37501 tttcctagtt ctgtctgcag tgctttttta gtcggcaatt gtgtgtcttc gacgagatag
    37561 gcaaaatagc cagcgcctat tccaatacct agagctgcga acatcaaaag aagaacagta
    37621 ataaaaacag tcaatgattg aaaaactcta aaaataatct taggaacaaa ccatttttct
    37681 ttttttcttc tattctgttt ttttcgagta tttttgcgtg gcaaaagggt cacctcaact
    37741 aatggtttta tttcgctaat tatagcaaat aatagaacaa aaaaacagac aaggctgttt
    37801 ttggcaggaa tttctttttt aaaagagtta aaacgtgaga aaatgatctt tattataaaa
    37861 gagttctt
//
LOCUS       DAFELK010000024        37591 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFELK010000024
VERSION     DAFELK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.025"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..322)
                     /locus_tag="LP433_001447"
     CDS             complement(<1..322)
                     /locus_tag="LP433_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ohr family peroxiredoxin"
                     /protein_id="HBL2005617.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQ"
     gene            complement(502..936)
                     /locus_tag="LP433_001448"
     CDS             complement(502..936)
                     /locus_tag="LP433_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2005618.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(1036..1884)
                     /locus_tag="LP433_001449"
     CDS             complement(1036..1884)
                     /locus_tag="LP433_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2005619.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            2273..4039
                     /locus_tag="LP433_001450"
     CDS             2273..4039
                     /locus_tag="LP433_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBL2005620.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            4141..5400
                     /locus_tag="LP433_001451"
     CDS             4141..5400
                     /locus_tag="LP433_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2005621.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            5547..6848
                     /locus_tag="LP433_001452"
     CDS             5547..6848
                     /locus_tag="LP433_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2005622.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            6851..7702
                     /locus_tag="LP433_001453"
     CDS             6851..7702
                     /locus_tag="LP433_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2005623.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            7715..8530
                     /locus_tag="LP433_001454"
     CDS             7715..8530
                     /locus_tag="LP433_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBL2005624.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            8681..9847
                     /locus_tag="LP433_001455"
     CDS             8681..9847
                     /locus_tag="LP433_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2005625.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            10077..10724
                     /locus_tag="LP433_001456"
     CDS             10077..10724
                     /locus_tag="LP433_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL2005626.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            10808..11752
                     /locus_tag="LP433_001457"
     CDS             10808..11752
                     /locus_tag="LP433_001457"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBL2005627.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            11887..13338
                     /locus_tag="LP433_001458"
     CDS             11887..13338
                     /locus_tag="LP433_001458"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBL2005628.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            13359..14195
                     /locus_tag="LP433_001459"
     CDS             13359..14195
                     /locus_tag="LP433_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL2005629.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            14195..14854
                     /locus_tag="LP433_001460"
     CDS             14195..14854
                     /locus_tag="LP433_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2005630.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            14980..15669
                     /locus_tag="LP433_001461"
     CDS             14980..15669
                     /locus_tag="LP433_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005631.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            15675..16631
                     /locus_tag="LP433_001462"
     CDS             15675..16631
                     /locus_tag="LP433_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBL2005632.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            16675..17187
                     /locus_tag="LP433_001463"
     CDS             16675..17187
                     /locus_tag="LP433_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2005633.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(17443..17991)
                     /locus_tag="LP433_001464"
     CDS             complement(17443..17991)
                     /locus_tag="LP433_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2005634.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(18080..19261)
                     /locus_tag="LP433_001465"
     CDS             complement(18080..19261)
                     /locus_tag="LP433_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBL2005635.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(19497..21005)
                     /locus_tag="LP433_001466"
     CDS             complement(19497..21005)
                     /locus_tag="LP433_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBL2005636.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            21164..21355
                     /locus_tag="LP433_001467"
     CDS             21164..21355
                     /locus_tag="LP433_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005637.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            21558..22475
                     /locus_tag="LP433_001468"
     CDS             21558..22475
                     /locus_tag="LP433_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBL2005638.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            22468..23541
                     /locus_tag="LP433_001469"
     CDS             22468..23541
                     /locus_tag="LP433_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005639.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            23689..24207
                     /locus_tag="LP433_001470"
     CDS             23689..24207
                     /locus_tag="LP433_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005640.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            24188..24580
                     /locus_tag="LP433_001471"
     CDS             24188..24580
                     /locus_tag="LP433_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBL2005641.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            24656..25591
                     /locus_tag="LP433_001472"
     CDS             24656..25591
                     /locus_tag="LP433_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBL2005642.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            25724..26503
                     /locus_tag="LP433_001473"
     CDS             25724..26503
                     /locus_tag="LP433_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL2005643.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            26496..26813
                     /locus_tag="LP433_001474"
     CDS             26496..26813
                     /locus_tag="LP433_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL2005644.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            27057..28667
                     /locus_tag="LP433_001475"
     CDS             27057..28667
                     /locus_tag="LP433_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2005645.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            28824..29672
                     /locus_tag="LP433_001476"
     CDS             28824..29672
                     /locus_tag="LP433_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2005646.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            29903..30382
                     /locus_tag="LP433_001477"
     CDS             29903..30382
                     /locus_tag="LP433_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005647.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            30415..32643
                     /locus_tag="LP433_001478"
     CDS             30415..32643
                     /locus_tag="LP433_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2005648.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            32772..34415
                     /locus_tag="LP433_001479"
     CDS             32772..34415
                     /locus_tag="LP433_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL2005649.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(34488..35033)
                     /locus_tag="LP433_001480"
     CDS             complement(34488..35033)
                     /locus_tag="LP433_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBL2005650.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(35056..35541)
                     /locus_tag="LP433_001481"
     CDS             complement(35056..35541)
                     /locus_tag="LP433_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2005651.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(35531..36343)
                     /locus_tag="LP433_001482"
     CDS             complement(35531..36343)
                     /locus_tag="LP433_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBL2005652.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(36482..>37591)
                     /locus_tag="LP433_001483"
     CDS             complement(36482..>37591)
                     /locus_tag="LP433_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL2005653.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        12331 a         6794 c         7424 g        11042 t
ORIGIN      
        1 cttgcgtttc ttccagagaa agaccttcga tagatccttc aatctctaca cctaagacaa
       61 agctcgtttc actttctgaa taaagggaaa cttgtgcact gacagtagaa gccccagaga
      121 tatttttttg ctgtttgatc aattctaatg cactgttaaa acatgcactg aaaccagctg
      181 caaacaattg ttcagggttg gttgcatttt cgacgcgttt accaggagct gcaatattca
      241 attcgaatgt acgatcggga ttatgcactt ctccagagcg tccgcctgtg ttgatcattt
      301 tcgtagaata catttttttc ataaaattac cacctttaat tatattttat acaattgaat
      361 tttacacaat ataattgtgg aaagcaaaga aatggattgg cataagataa ataagagaaa
      421 gcacatgaaa cagacgcgct ttctcgaata gcaaacatat acaaaaaata tcagagacaa
      481 aaaataatct catcataaac attacatata tttctcaaaa agttgttttc tttcttcaaa
      541 aattacttca cgatggacct gatgaagcat ccataaataa ccaaaaggat ctctgaacat
      601 tgagttagtc acaccaaagt ccatcatttc tgtcatttct tgaatctcta cacagccatt
      661 tcgtaatgct ttattatgtg tgtcctcgat atcagagacg atgatattga accagatcgt
      721 atttggatgt tcagcagtag gagcagtcaa accaagagac gtgttttcat ccagcatatg
      781 gaatctcgta ccatacaagg taaaaatgac ttcattattg cctctagggt aatctgttgc
      841 ctcaatcagt tgtatttcat caaagattgt ttgatacagt tctagtgctt tcaaactatc
      901 atttaataca aaatcgattt ccgttccttt atgcataaag atctcctctc cttttcagtc
      961 gaacagttac tagattcttt tattatacca gctaaagaaa acgcattcaa aaaaatagcg
     1021 gatttactta ccaactcatt cgattggatg ataagtaaat ccgcgtccca ttacttctgc
     1081 tacgctgctg acaatgacaa aggcacttgg atcgatttct tctatcaatg gtttcattcg
     1141 ggaaaattca tgatcagtca caacgatcaa taaaacctct tttgactttc gattataccc
     1201 gccttttgcc tctagcaggg taaggccacg tccaatctca gcacttaagc gaaggcggat
     1261 gtcttccaaa taatgttcac tcatgaccat aacagatttc tttcgattga tacctgtttc
     1321 gatataagtc atgacaattg aagtgattgc aatagataaa atagcataaa gaaactcttc
     1381 tattccaaaa ataaacagat taagagaaac aacgaatgcg tctgtaaaaa ataagccaat
     1441 cgaagtattc aagtggaaat attttttaaa aatgagggga gggatcgtcg taccgccgct
     1501 agaagagttg tttttatata aaatcgcaac tcctaaagca aaaatcgcac ttccaaaaat
     1561 gacagacaac aaccgatctg aagtaatcat tgtttctgga actattgcaa tgattaaagg
     1621 aaaaaccaag cttccgaaaa gtactttaaa aaagggtttt ttacctaaaa atagaagagc
     1681 tagtaccaac ataacgatat tcaacactaa aataactata gctcggtcaa agcctaaagc
     1741 agcttccagt aatattccta gaccgctgac acctccagca gcaatatgat gaggccctaa
     1801 aaacatattg atagcgactc ctaatatgaa gagggcaaaa ataatcttaa tgtatgtcca
     1861 tataaattgt ctcgtttctt tcatttattc acttccttaa ttcattaata atactcttat
     1921 cttattataa cttacttttc accttaagtt aactttaatt aataaaaaaa ttaggctagt
     1981 ctaaattatt atgtttcatt cttctagaat atacttctac gccaaaaact gttaaaaaac
     2041 ttttacttta gaaaattgga gaaattgatc gcttaagata aattcaggac actaaatagt
     2101 acaggaagta gactaaaact tttaaaagtt ttaagtctat ctatttggca agtttaaaaa
     2161 ataaaaattc ggtatcaaaa aactgttacc gataacattt ttgaaagcgt tgtcttttgc
     2221 ttctctatca cttatagtga tgacgtcata ttaaaacaca aggaggaaat caatggatac
     2281 agctgcaatt tatcatcgac cggaaagtga atatgcattt ctatatacga atacaagatt
     2341 tcgtattcgg cttcgtacta ggaaaaatga tatcaaaaaa gtatatgtgc tatgtggaga
     2401 tccatatacc ataacaactg aaaaatggta tcaaaaacaa cgaccaatga aaaaatgtct
     2461 aagtaccaat gttcatgatt attgggaaat tgaagtgacg agcgaaacaa gtcgcttaca
     2521 gtatgcgttc catgttgttg gggaagataa cacggactgt ttttacggtg atcaaggaat
     2581 ttttccttat cgagaaaatg tgattactga accaaatttt tattttcgaa taccttattt
     2641 tcatcaaatc gatcgattca ctattccaga atgggtaaaa gaaacagtat ggtatcaaat
     2701 ttttcccgaa agatttgcaa acggggacaa agcaaatgac cccgaacaca ctttaccttg
     2761 gggaagtaaa gatccagacc gagaagactt tttcggggga gatttgcaag gtgtgatgga
     2821 tcatttggat tacttgacgg accttggcat caatggcatc tatttttgtc ccatatttaa
     2881 agccacatcc aatcataaat acgatacgat tgattattat gaggtggatc ccgcttttgg
     2941 cgataaaaaa cttttaaaaa acttgattga tgaagcacat aaaagaggga tacgtatcat
     3001 gttcgatgct gtattcaatc atatgggtgt ccattcacca cagtggcaag acgttctcaa
     3061 aaacggagaa aaatcgatct ataaagactg gttccacatc cgttttttcc cagtagattc
     3121 ttatcagatg actgacttac cagaaactgc tgaaaatatc ccatatgata cttttgcttt
     3181 tactccattc atgccgaaac taaatacagc aaatccagaa gtgcaaaaat atttgctgga
     3241 tatcgcaact tattggataa aagaattcga tattgatgga tggcgtcttg atgttgctaa
     3301 tgaagtcgat catcattttt ggaaaaaatt cagagaagca gttacagaaa tcaaaccaga
     3361 catctatatc cttggagaga tttggcattc ctctcaagct tggctgcaag gggatgaatt
     3421 ccatgcagtg atgaattatg catttacaga ttcgattaaa gattattttg caaaaaagaa
     3481 aatcacagct tcacaaatgg tcagtggaat gaatcatcag caaatgcttt acagagatca
     3541 ggtgaacgaa ggaacattca acttattaga ttctcatgat actgccagga tcttgaccct
     3601 ttgccaaggt aacaaagaat tgatgaagtc tgtgatggcc tttatgtttc ttcaaaaagg
     3661 gtctccttgt atctattacg ggacagaaat agggatgact ggtgaagatg acccggattg
     3721 ccgcaaatgt atgatatggg agaaggagga acaagatcta gagctattcg gttttataaa
     3781 agaacttgtt tctctaagga aacagttgtc taagattatt tctgaaggtt ctactcagtg
     3841 gctaatagta aatgatcgtg aagataagct ctatttcaca cggaaactag agggacagat
     3901 catctatgtt tactttaatc agtcaaaaga accttgggta gtagaacagg aaaatgaggt
     3961 gattcttagt caaaattgtc agttgttaga agacgggaaa gcagagatac gacaatacgg
     4021 atttttgatc atgtgttgaa aactgttacc ggtaacaaca agaaagcgtt tgcaaatgaa
     4081 gatttgtgcc cattataata agggtgtaac agcacgttga atacaaagga ggaaatgaag
     4141 atgaaaaaaa gaagtgtgaa acagttgggt ttagggttaa tctctttagg aatcttaggc
     4201 ggattagcgg cttgtggcaa tggtaactct tcagcagaag gggaagccga tgaaggaaaa
     4261 acgttaacag tttccgttga ttctggatat aaagattata taaacgaaat aaaaaacact
     4321 ttcgaaaaag aaaacgatgt gaaaatcaag ctagtagaaa aggacatgtt cgatcagttg
     4381 gaatcattag cgttagatgg gcctgctgga aagggacctg acgttatgat ggcagcatat
     4441 gaccggatcg gtgcgttagg acagcaagga catctggcgg aagtaaaact gggaaatgaa
     4501 gcagcttacg atgaaacaga caaagcccaa gtgacttatg atggaaaaat ctacggagaa
     4561 cctgcagtaa tcgagaccct tgttttgtac tataacaaag atttagtcga tacagcacca
     4621 tcaacgttta aagatttgga gaatctatcc aaagacagtc gttttgcttt tgagtcagaa
     4681 gcaggaaaaa atacaggatt tttagctaaa tggactgact tttattattc ctatggttta
     4741 attgcaggtt acggtggcta tgtatttggt gatgatggca caaatccttc agatatcggt
     4801 ttgaataatg caggtgctgt agaaggaatc tcttatgcaa cagattggtt caaaaatgtt
     4861 tggccaaagg gaatgcaaga cataaaaagt gcaggagact tcgccagcca gcaattcatg
     4921 tccaataaaa ctgcagcaat cattgacggt ccatggcaag cgcaaacata caaagaaaac
     4981 aatatcaatt atggtgtagc caaaattcct actctaaata atggacagcc ttatcaaccg
     5041 tttggcggag gaaaaggatg ggtagtcagc aattatgcta aaaacaaaga cctctctcaa
     5101 aaatggcttg attatgtaac gaatcaggaa aatcaagaaa aattctttga aatggtaaat
     5161 gaaatccctg caaaccaaca agctagggaa acagcaaagg ctaaaaacga tgaattaaca
     5221 acagctgtga ttgaacaata tgaaacagct caagcgatgc caaacatccc agaaatgggc
     5281 gaagtttgga caggtgcaga aaacttgatg ttcgatgcag catcaggttc aaaaacacca
     5341 aaagaatccg cagatgaagc agtaaaaaca atcagtgaag ccatagaaca aaaatactga
     5401 ttaaaatgat aaccgtccat ttttataaaa aatggaacag gtgcttcaga taaaagtggc
     5461 aagagcgaga tggaaaatta tcttgctctt gttgccatta tcttaaaagc agtttgcggt
     5521 ttagcaagtt tagagggggc attcagatgc agcaagataa aacaagcaat atcaacgaaa
     5581 aaaaaatcac gctttgttca cttattccag ggatggggca gtttgtaaat ggccaagctt
     5641 ttaaaggtat cgtttttttc gccatattcg tcctattcat tggtcagatg cttctgggcg
     5701 gatttcatgc attggtagga ttggttactt tgggaagtat accaatggaa gatcattcat
     5761 tatttatttt gattgaaggc actttgcaat tcatcattac aatcattttc ttgatttttt
     5821 acggtttgaa tcttttagac gcttatcgag tagcgaagat gcgtcaagag ggcaaaaaaa
     5881 tcaatcggac gatgaaggaa gtcatacata atataggtga tgaaggtttt ccttatctat
     5941 tgacacttcc cgcttatctt ctcatgattt ttacgatcat tttcccagtc ctagttacat
     6001 tgttcactgc atttactaat tatgacttca atcatattcc accagccagt ttaattgatt
     6061 gggtaggggc taaaaacttt tttagtatct tctttttaag ctcatatcgt aatacttttt
     6121 ttgcagtctt ttcgtggacc gtgatttgga ctttatgtgc aacaactttg caaatcaccc
     6181 ttggtattct cacagcggtt gttgctcacc agaaatttat taaattcaaa cgtattttcg
     6241 gtatcatttt cttattacca tgggcggtcc cagcttttat tactatcatg agtttttcga
     6301 atatattcaa cgatagcgta ggtgccatca atactcaagt gattcctttc ataaaccagc
     6361 ttccttttgt agatatcagt gcaatctctt ggaaaacgga cccgaactgg acgaaagtag
     6421 caattatctt agtgcagggc tggttaggat ttccctatat ctatgtgatg gttacaggaa
     6481 tcttacaatc gatttcagaa gacttatatg aagcagcaaa aatcgacgga gcaaatgcat
     6541 ggcagcgctt ttcaaacatc acgcttcctg ctgtcttcct agtggcagcg ccaacattta
     6601 ttacacagta tacggggaat ttcaataatt tctccatgat ctatctgttt aacaatggcg
     6661 gtcccggaag cgtaggcgga ggagctggtt ctactgatat tcttatttcc tggatctata
     6721 aacttacgac tggaacttct ccgcagtatt ctatggcttc agcaatcacg ttgattatct
     6781 ccgtcatcgt tatctgtgtg tcattgctgg tatttaaaaa gacaaatgcg ttcaatatgg
     6841 gggattaaca atgaaaaaat ttcattcgag tgctcgattc caaaaacgac tttctcactt
     6901 ttttacttac ttttttcttt taatactgtc agtcattatc atctatccgc ttttgatcac
     6961 agcaagtact gccttcaagt caggaaatat tgcagctttt agtttagatc tttcaagtga
     7021 ctggacttta ggaaacttta ctcggctatt cagtgaaaca ctttacggga cttggtataa
     7081 aaatacattg atcatttctg tcctaacaat gatcgtacaa gtgactgtag taactttggc
     7141 gggctatact tatagtcgct atcgttttat cggccgcaaa tcaagtttga tgttcttttt
     7201 agtgattcag atggtaccga ctatggcagc attgactgcc ttttatgtca tggctttctt
     7261 attagaagcg ctcgataagt actggttctt gacaatgatc tatataggcg gtggaattcc
     7321 aatgaatact tggctgatga aaggatactt tgacactgta ccaatagatt tagatgaatc
     7381 tgctaaactt gatggggcag ggcatttcag gatttttttc cagattgtat taccgcttgt
     7441 caaaccgatg ctcgccgttc aagcattatg ggcttttatg ggaccttttg gggatttcat
     7501 gttagctaag ttcctgcttc gaacacctga aaatcagact gttgctgtcg gcttacaaac
     7561 atttatttct gatgtgacaa accaaagagt ctctcttttt gctgctgggg caattttgat
     7621 tgcactaccg atttgtctat tattcttctt tttacaaaag aactttgtta ccggcctgac
     7681 atctggcgga acaaaaggat aggagcagag tatcatgcaa acatttccgt taaactattt
     7741 ttccgcatta cgtacgccaa ctcaagtgtt tgcgggacgc aaactattat catggcctaa
     7801 atttttcttg atatttgtat ttttagtttc cttgatggtc atgcctgtga ctctttttta
     7861 tgccaatcag atccaagcga ttccattaga acaatttcta tccgttcatt cgctgatcga
     7921 tgaacaagga acccaaaaat tttctgaact tgaattatct gaaactgggt tacaagcatc
     7981 gcaacaaacg atagctgtga cccctgaaat tttggtaggt gtgtctttat ctgagaaaca
     8041 acaatccgat catggaactt ttattgattt tgagaaggaa caatgggtga tccaacaaaa
     8101 ggataaatct ggtatacgcc gctatacgat gaattatagc ccatctttcc aaccagattc
     8161 tgtacgtacg cccgaagatt tccaacgatt tttagaaaga gaattttatg ccagtaatcg
     8221 tccaacaatc attttatctt atagtttaag tcttggtctt gtcctatttg tcatgacgag
     8281 tctcatttta ttcggggctt cctttttctt gtggatgaca agaaaaagcc aactttcatc
     8341 cattcataca ttcaaagaga gtgcaaattt gatgctgaat gttatgggaa taggttccat
     8401 ggcagcagca gttgtagggt ttatccactt tgactttatc ttgatgctaa gtgtccaaac
     8461 aacgataact gtcttgctgc ttttatgggt ttttgtcaaa acaagattca aagataagcg
     8521 tgtcgaatga caagtttaag cgatttatgc gacaatgaat gtgaaaaaaa tgaaaaataa
     8581 agtagttttt gaaaaatttc tgaaaaaatt aaacttctta gttgattctt ttctttttta
     8641 gtattaacgt aatagggtag tttttttaag gaggaaaatc atgttagaga aaactttata
     8701 caatcaatta ttttcacgtt ctttctcgct ccctgtcgaa gtaaattatt gggacggtac
     8761 aacgaaacaa tacggagata cggacactcc tccccaaatc aaaatcaata tccatgaaga
     8821 aatcccaatg aaagagatta caagtaacgc atctttggca ctaggagaag cctatatgga
     8881 tcatcgaatc gagatcgagg gaagtatcca agcattgatc aacgatgctt atcagcaagc
     8941 aaacagcttt ttacgaggaa aagattatct aaaatggctg ccaaagaaag aaaaacatac
     9001 gaaacaaaaa aacaaagaag atatccatgc gcattatgac ttaggtaacg acttttataa
     9061 actttggcta gatccaactt tgacttattc ttgtgcttat ttcaatacac ctgaagatac
     9121 gttggaacaa gcacaaatca ataaagtcca tcatatctta gacaaactct ttatcaaaga
     9181 aggcgaaacg ttgcttgata tcggttgtgg ctggggaaca ttgatgttca ctgctaccaa
     9241 agagtataat gtcaaggcaa ctgggatcac actaagtgaa gaacaatacg atttgattac
     9301 caaaagaata aaagaagaac atttagaaga taaatgccgt gtattattaa tggattaccg
     9361 cgaactaaaa ggcgaaacgt ttgatcatat cacaagtgta ggtatgttcg aacatgtagg
     9421 ttctgaaaat cttgaaggtt atttcaaagt ggtaaaagat ttattgaaac caaaaggaac
     9481 agctttgatc catggaatca gccgacaaca aggcggtgcg acaaatgctt ggatcaataa
     9541 atatattttc cctggcggtt atgtccctgg tgttactgaa ttagttgata atattacaaa
     9601 aaacgatttg caactgattg atttggaaag cttacgtcgt gactaccaat tgacattaga
     9661 acattggaca aagaattttc atcaagtcca agatcaagtc acgaaagaaa tgggtgattc
     9721 cttctatcga atgtgggatc tatatttaca agcttgtgca gcttcatttg aatcaagtaa
     9781 tatcgatgtg attcaatatt tgcttgttca acctggaaac aatgacatcc caatgcatcg
     9841 tgcataattg aggcaaaagt actgtttaaa gactatttaa aaagaagcta agttttatga
     9901 tgctccagaa gtgaactttt ttgtctaact tctaggattg tctctaaagc ttagtttctt
     9961 tttctttata ttttcataat aaaagtttgg ttctttaatt tttaaacatg acagaaaatt
    10021 ttttcttcgt tatacttgta atagaatact attttataac aaaggggatc gaatcaatga
    10081 aaaaaactgt tatttatact agtttatttg cagctttgtt tttagctgct tgtcaatcaa
    10141 ataccaatca aggcacatct gggaatacgt cttccagtag cgaacagcgc tcttcacagg
    10201 tatcggactc ctcaacaaaa gcaagcacat cttcgtctag ccagacaaaa agttctagtg
    10261 aagcaagtac tcagtcagat atcaaagtgt ctgcagctcg tgcgatcgaa ttgttccaag
    10321 ataaataccc agatactgca attactagtt tggaattaga tagtgattgg ggatcttact
    10381 tctacaagat agaaggtgtc gatgatcaaa aagaatacga agcaagaatt gatgctcaaa
    10441 atgaaaaaat ggagacagag aatccagaaa ctctagatcg agatgaacaa aatggtcaaa
    10501 agaaaaaaga agatggtctg gatgttgata aattgatcac gattgaggaa gcagcaaaaa
    10561 tcgccgtcga caaagtagga agcggtacgg caacagattg ggatttggat aaagatttag
    10621 gtactactta ttgggaagtc aaagtaaaag acggcaatca aagtacatca gtcaagatca
    10681 atagccaaac aggcgaagta ctgtcaactg aacaagatga ttaagaattt cttcggaaaa
    10741 caagagttga tttttctttt agtcatgata cactagacaa aataacttgt ttgaaggagc
    10801 gatttacttg agtttagaaa cgacctttgc caatcatatc tttgccaatc ctttgatgaa
    10861 tgcatctggt gtccactgca tgactaccca ggaattagat gaactggctc attcagaagc
    10921 aggagcattt atcactaaga gctgtacgat caatgaacga aaaggaaatc ccgaaccacg
    10981 ctattttgat gttcctttag ggagtatcaa ttctatggga cttccaaact taggtttttc
    11041 ttattatcta gagtatgctc ttgcgtatga aaaagtgcag gaaaaccaaa atcaaccgtt
    11101 atttttttcc attgccggga tgagtgtcca ggaaaacttg gaaatgcttg agaaaataga
    11161 aaaaagtggg tttaatggga tcactgaatt aaatttatct tgtcccaatg tgcctggaaa
    11221 accacaacta gcttacgatt ttgaggccac ttatgaaaca ctgaaagaag tattcagcat
    11281 cttttctaag ccgctaggaa tcaaattgcc tccttatttt gattttgctc attttgatca
    11341 gatggctgat atcttgaatc agtttccatt gacctatgtc aatgctatca acagtgtggg
    11401 caatggtttg tatatcgata cagaacaaga agcagtagtc atcaaaccaa aagaagggtt
    11461 cggcggcatt ggcggagagt atatcaagcc gactgctttg gcgaatgttc gcgcttttta
    11521 tacacgtttg aaaccagaaa tccaaatcat tggtacaggt gggattcgga caggacaaga
    11581 tgcatttgaa catctgctat gtggcgcaag catgttacag attggtaccg agcttcataa
    11641 agaagggccg gaaatttttt ctagaatcat aaaagaatta acgcagatta tgtcagaaaa
    11701 aggatatacg tcaattgacg aatttaaagg caaattacgc accatttcat agcaaagaga
    11761 cgaaggtcat gattgatctt cgtctttttt tataaaaaac actcgtctgt tcattcctgt
    11821 gcaagcgtac tcattgtatg ttagacgaac ttgtgggaaa ataacagagg caaaaaggag
    11881 gataatatga atgatgcaac agaattagca aaagagctta aagaaaaaga atttagtttt
    11941 caagaactag ttacggatat acagaaaaaa ataaagaagc aaaatcatga attgaatgcg
    12001 tttgtcgcgc ttgaaccatt cgagagtaat tcccacgagc tattgattcc ccagtcagaa
    12061 aaagggccat tggctggtat cccatttcct ttaaaaatgc tcggtcaaga aaaaaaggga
    12121 tggctagcta cttcaggatc tcgtttattt gaaacacacc gagcttctca tacatctaat
    12181 tatgtgcggc aagcagaagc gataggtcta gttccttttg gacaaaccaa tgcgccagag
    12241 tttggtttca aaaatattac agacccagtc atctatggcc cagcaagaaa cccttggaac
    12301 cttgaatgta caccgggcgg atcaagtgga ggagctgctg ctgcagtttc atcaggaatc
    12361 gttcctttag ctggtgctag tgatggcggt ggttctatta gaatacccgc ttcgttttgc
    12421 ggattgattg ggctgaaacc ttcgcgaggg acgatgccag ttggtccata tgcttggaga
    12481 ggatggcaag gagctgctat tgatttcggc ttgacagttt ctatgagaga cacggaggct
    12541 ttattttatg ggatgagaag tatccattcc ggtgcgccat atcaagtatc gccagttgag
    12601 tggcaaacac atccaagaaa aaaacggttg aagatagctt tttgtgttga ttcaccgatc
    12661 cactcacaga ttagtgaaga ggcagtactt gctgtaaaaa aagctgtaga tttccttgga
    12721 aaagaagggc atgatttgac agagattcct tacccactag atggtcgtaa actgatcacg
    12781 tcttattatc agatgaatgg cgcagaaaca gcagcaatga tccgctcgat tgaaacaggc
    12841 atccagcgag ctgtcagaaa agaagaactt gaacccattt cttggacttt gttccaatat
    12901 ggtcagaagc tctctgccgc tacttacatc gattctctgc atgtatggga tgaagcagca
    12961 attgtcatgg aaaacctaca tcaagaatac gatctattcc tttcaccaac gactgcattt
    13021 accgccccta aaatcagcga agatttgcaa agtgatgcga taagagcaca gatggaacac
    13081 atcagtgatt gttctgaagt agaaggttta gacgttgttt cttccatgtt tgaggagagc
    13141 ttgaagatca caccttatac acagttggct aatctgactg gacaaccagc aatcagcttg
    13201 cctactcatt tgacaaaaga aaacatgcct ctaggaatcc aatttatggc tgccagagga
    13261 agagaagatt tgctatttca aatcggctat ctatttgaag caaatcatca gttccattta
    13321 ccaaatccat ggaaatagca gaaacaagga gaagaagaat gaagaaaaaa agattgtttg
    13381 ctctaataac tagtgccttt tttattttaa gcgcttgcgg tacagctgcc gctaatcagg
    13441 aagataacag ctggagtaat gtagaaaaaa agaaagaatt agtagtagcg acttctggca
    13501 cactgtttcc cgcatcttat tataatgatc aaaatgaatt agttggttat gatgtagatt
    13561 tggcaaaaga ggtggctaaa cggttaaatg tcaaaatctc ctttaaagaa tacaacgtgg
    13621 atggacaaat cacttctgtt tcaaaaagag aatcagattt tgctgcgaac gattttggta
    13681 tcacaaaaga aagagaaaaa aaattctccc tttcagagac tttcaaatat tcatttgaca
    13741 gtatgatcgt acgaaaaaaa gatgattcag gaatccactc acttgaagat cttaaaggga
    13801 aaaaagcagc tggcgaaccc aatactagct atatgcgttt agcggaaaaa cacggagcta
    13861 aattagtcac atatgacaat gccacgaatg atcagtattt aagcgatgta gcaaatggtc
    13921 gaacagatgt tattctaaat gattattatc tgcagaaaat ggccgtatct gctttaccag
    13981 atatccctgt aaaaatactg gagaacgttt atttcaatga aaacgaaagt ggttttttat
    14041 tgaaagaagg aaatgatgct ctgaaaaaga aaatcgatgg cgtattaaaa gagatgaaag
    14101 aagatgggac gacaaagaaa atatctgaaa aatattttca aactgatgtt tcagtcaaac
    14161 cgaaagaaac gatggctgag tcggtgagtg agtgatgtac tttcctctaa ttgatttttc
    14221 cctcatgtgg acttcacttc ctttcgtact gcaaggcttg gtatacacat tagggattgg
    14281 cttcgtgtcg tttcttttag gaaatctggt agggttgctt ttgacagttt taggtctttt
    14341 ggattggctg cctctgaatg tatttattcg tttttattta tcgttcttta gaggcattcc
    14401 cgcactagtc ctgctgtttc tgttatattt tgggttacct tatcaattaa gtgccttaac
    14461 ggcttcagtc atctgcttta cgattaccag cagtgcattt attggtgaaa tctatcgagg
    14521 atcactagca ggcgtttctt caggtcagtg ggacgctggt ttagcttctg gtttttcttt
    14581 ctttggggta ttgaaatata tcgttttgcc gcaagctttt cgaatctcag taccggcact
    14641 cagtaacgta gctatggatc tagtgaaagg tacttcgtta gcagcaacaa tcacagtgcc
    14701 agaaatattt caaaaagcaa agatcatagg cggtcggaca ttcgattatt tttctctcta
    14761 tattttagtt gcactgattt attgggtcat ttgtatcggg atcgaaaaag tgcaacagta
    14821 tttagaaaaa cgttctatgc atcagtcaat ctgaaaaata gaaatggtgc tagcgtggct
    14881 ggcaccattt ctattttttg tttcttgtat attctgccta gtattttaaa accatttcat
    14941 gtaaaatgta aatcgaaaat atgttcggag gtagaaaaca tgaagacccc gctaaccatc
    15001 gaaatagaat cctcgttata ccaatattgc atcgagcaag gcggcttggt tgtagaagaa
    15061 gtcacgatgc ctgatgacca aggaattgta gatacgctta gctgcttgac aaaatttgat
    15121 ggaagccgag aatggcgatg ctatgagctg aaagtgacaa aagcagattt tcgctctaca
    15181 gccaaactgt catttgttgg acattataat tattttgttt taccaagtaa actatatgaa
    15241 gaagtaaaaa ctgaaatccc tacaggaata ggtgttttag tgtatcgtcc gtacacggtt
    15301 gaagaggaga tgcctgcctc tggtacattt ctgattgcga aaaaagcagc aaagaaagag
    15361 cttgctgtac cggaagaagc tttgacaaac cgcttcatgg cttctttatt cagggaagta
    15421 agaaaagcaa agcaaatgga gcgaggcgta aaatattttc caacagatca attgtacaaa
    15481 gaattgaaaa gacgttcaga aaatcaagat ccattttcta acgaacgata ttatgaacgg
    15541 tttttagagg aaatagctag tcaggcaatc aatgagttgc aagaagaagt tatcgcgctt
    15601 cagcatgatt atgaatattt gaggcaacaa cagcagatcc gtcggttgcc tacagagcca
    15661 ttggagtgaa aaatatgtac tatccttatt taagaggaaa acaatttgac ctattagcat
    15721 taaaagaagc actgtcgcga ggattgctct ccaataaaat ccaaccagtg atcgaaccag
    15781 tacgtgattc cgctacgctt aaaaatgtga tcgaattatt tcaaaaaaag caccatcgaa
    15841 tcgctgtgat ccaaaatccc caagtaggac aattcaaatt attcgatcag catgtgcaca
    15901 gttggacagt caaagaaaat agctctgtcg tccctgcaca gatcttaacg ccagaaaatc
    15961 tcagtgaagt actggattca cctccagcgt ttcttgtttt cgatggacag cactacccaa
    16021 aagatacaga ggtgtggaaa cagttggcag gagttgattc gaaatttttg ataccagata
    16081 ctagtcgctt tcgcatctgg ctgcccgaaa acaaaattgt gatccgtgac tcttttcaaa
    16141 cgagaaagca tgttgaaagt tatgcagata aaacagatga cttttttagt gatgactatc
    16201 tttttttcca cgcagacgga tatattggat tttctgattt cacgatcgaa ggtagccgtt
    16261 atttcgataa agggttccct agccgagcgc ttgctatcca tctaacgtat attgatgctt
    16321 acggcaatat acgcgtgaaa cattttgtct ctgacagtaa cgactctgct aaagaccaag
    16381 cattgaagtt tcttgaagca ggagataaaa tgaaaaaatg gatcatgcgt caccatcatc
    16441 aactcttgat tacttcagga atgattgaat tattggctct ttaccagcaa caaaaattcc
    16501 ctggactggg agtgttgaaa aagtggtcac ttatgcatca tttggaactt attagtcacc
    16561 tgctagatca tccaaaagat tggcttaaat attattcaaa agttcaggaa ctatatgaag
    16621 tgatccaatg attagataat gtaaatgaaa aaggaataga aaagaggaaa ctggatgtat
    16681 attcggcaaa caaggaaaga agaagtagaa gaagtggtag aaatcattaa tgccgcagcg
    16741 gatttcattg cttcgcaagg ctctcctcaa tggcaaaacg ggcagaaacc aacaaaagaa
    16801 acgattttga acgatattga aagaaaagaa agctatgtat taatagtgga agatcaaatt
    16861 gctggaacag ctgcattagt ctcaagcgtg gatcccgttt acacaaaaat agatggtagt
    16921 tggaaagaat caactggtcc ttatttatcg attcatcgtg tcgctttagc agaaagtact
    16981 cgaggaaaaa aactagcaaa accgttctta gaacatttgt tgacgattgc agccagcaaa
    17041 aatatccaag atatccgtat cgatacttat ccagctaatg aaccgatgga aaagaccatc
    17101 tattctgctg gattcactta tcaagggatg attgaatttc cttttgaaca cggcgaaaga
    17161 aaagcatatc aaataatcat caattgacta taaaatcatc tgagcaaaga taaagacatt
    17221 aacactactg aaaaaaacaa tcatatgata gccaagaggt tgtaacagaa gtggccagct
    17281 tcaaaaaaca agaaagaatt tccgaaaatg cttctcaaat ttttgtggaa ttttagcgta
    17341 ttttacgaaa tagctgcttt ctgaaactcc cttcatcgag aggtcgtgac atagcttttg
    17401 tcacgacctc tcggcttatc ctacgagtat tattcgatac atttatatca ataatccttt
    17461 ttttatttta tctgcagctt cttggaacgc tccatcgttt gacacgacta aaagtgaggg
    17521 gatagctttc aaacgtttca actgtgctaa atcttctaca taaaccgcca gtctggctga
    17581 aatctgttca gatgaatctc cacgtttttt caggcgcgat tgcaatgttt ctttagagat
    17641 cgtaataaag ataggacgga ctaccgtccc gaaatactca tataaatgcc aaaaaccatt
    17701 tgctgtcaaa acggcgtaac aatttcctac tgtcagtttc tttttaattt ctgctttact
    17761 ggaaccatat ttatgttgag catattggtc ccactctgca aactcatttc ccttgatcat
    17821 ctgattgaat gtattgtcag aaacaaaata ataatcctct tgatcttttt ccccaggtct
    17881 tggtgatcga ttcgtgtaag taatgatctt ttgttccggc tgaaaaatag cttctgcgag
    17941 tgaagttttt ccagaaccag aaggaccgat aaatacatag caataattca ttgtcatttc
    18001 tcctttgatg attgaacaag tgaaaaagct ttggaaaata tttccaaagc ttttaaaagt
    18061 aactttgctt ttttgtatat tataccagca agccagtcac aatagcactt aaaaagctga
    18121 ctaaagtcgc tgttagcaaa attttcaatc cgtgttttgc gacaagattt cctttttctt
    18181 catttaatcc cttcatcgca ccagaaatga tcccgataga agagaagttg gcaaatgaaa
    18241 cgaggaagac agatataatt gctgttgtac gctcagtaaa atggaaatta ccatttgcta
    18301 attctgtcat agcaacaaat tcatttgtaa ccagtttagt cgccatgata ctaccggcat
    18361 ccactgcttc tttccatggg attccgctga tgaaggcaag aggggcaaag atgtaaccta
    18421 ggatctcttg gaaagtgatg ccgaatatcc cgtggaagat agcattgatc atggcaatca
    18481 aagcaacaaa accgataagc atagcagcaa ccgtgatcgc cacatggaaa ccatcaagaa
    18541 tgtattctcc caacatttgg aaaaatgtct gttctttgtt ttcttcaatg atcagctcat
    18601 cttctttttc ttctaataca tagggattta caattgaagc cagaatataa ccgccaaata
    18661 agttcaaaac aagggcagtg atcacatatt tagaatcgat cagtgccata taagatccga
    18721 cgatcgacat agaaactgta gacatagccg atacactcat ggtgaacaaa cgtttctcag
    18781 ataggaaggg taattccttt tttatggaaa taaaaacttc cgattgtcct aaaatagcag
    18841 aagctactcc attataagat tccaatttgc ccatcccgtt gattttactt aatcctagac
    18901 caacagcttt cataaataat ggaagaatct tgatatagcg tagaataccg ataatagcag
    18961 aaataaatac aattggcatc aatacggaaa gaaagaaagg tgcacttcct ttatttgcta
    19021 caccggcaaa aacaaagtca acaccttgcc cagcaaaagc aagaagatga tcaaacattt
    19081 ttgccaatac agaaacaacc gctgtaccaa aagttgtacg taataatacg aaaccaagaa
    19141 caagctgtaa aacgaacatc acaattagtg gtttcaattt gattgctttt ttgttactgc
    19201 tgatcaaaaa agcaagccct aatgtgacaa ataaaccaat aatacctaat aaataactca
    19261 aataatcact cctattccaa attccgtttt attttacctg ttttgcaaat aaaatactaa
    19321 tctttagtga aattttcatt acttttttag agtgaaacgc attcattttc cattagaaaa
    19381 taaagcgaac aaaataaaag gtttaaaaag tgtaacgtct tagtaaagtc tataaaaaaa
    19441 cgaaactatc gattaagcta atagtttcgt tttcaacatt tataagtaaa ctttttctat
    19501 tggtaatata gattttcgga agggtagaca ggtgcgcagg taatatcgat tcctagtttt
    19561 ttcaatgttt gttcatcatt tttattgacc atcacagtag agtgggcttg tgctccctca
    19621 agttcagcta gtttatcata agcaacttga gcgattggat tcgttactgc actgattgat
    19681 aaagcgatca agacttcatt gatgcttagt gcatccaaag aggaatgaag tgtctttgat
    19741 ttcaatcctt gtattgtttc aagaactaat ggtgacaata aaggaatgtc atctgcgata
    19801 tgggctaaat gttttactgc atttaagata actgccgctg acgcatccat caatgaactt
    19861 gtacgcccgg taatgatgac ttcatctggt aattcgattg caatcacagc agaaggatct
    19921 tttgtaggac tttgcgcttg aatcttatct gcatagtcat gggcagggac taccacgttt
    19981 cggtcttcag gacgtaaacc gacttcttcc ataatcagtt tgattcgatt aactgcttct
    20041 tcgtcgatca atcctttttt gaagtcgcat tctgtttgga aataacgacg gatgatttct
    20101 tgtttagagg cttcttggac aacggtatca tccacgatcc caaatcctac acgattcaca
    20161 cccatgtcag taggagattg ataaacagat tctttaccag taattttttc aataatacgt
    20221 ttgattacag gaaatgtctc aacatcccga ttatagttca cagctacttt attgtaggca
    20281 tcaaagtgga aggaatcgat catattgaca tcttttagat cgactgtggc tgcttcataa
    20341 gcaatgttca gcggatgttt caacggaaca ttccatactg ggaaagtttc gaacttggag
    20401 taaccagctg catgtccttt ttggctttca tgatacagtt ggttcaagga agtagcgagc
    20461 tttccacttc ctgggccagg agctgtcact acaacgattg gtttagttgt ttcaatatac
    20521 tcattttttc caaaaccatc ttctgagacg attttttcta cgttgactgg atagtcttcg
    20581 atttctgagt gtttatagac cttgatgttt cgtctttcta gtttattgat aaagactttc
    20641 gtggcaggct gtccactata gcgagtgata acgacactgt tgattaataa gccataacca
    20701 cgtaattcat cgattaaccg caagatatcc atatcataag taatcccata atcaccacgg
    20761 atcttattac gttcaatatc tccagcatag acgcaaatca gtatttcagc ttgatctttc
    20821 aatttttgca gcaatttgat tttcgcatct tcttcaaatc ctggaagtac acgtttcgca
    20881 tgcttgtcgt caactagctt cccaccaaat tctaaatata atttgtcata gtggttcact
    20941 cgttccaaaa tatacgctga ctgctcttca atatattttt ctgaatcaaa accaattttt
    21001 ttcactaggt tccctcctta agtactaaag cattttttca tttttttgag gattcgtcaa
    21061 ctggaagagc gaaattcctc aaaaaaacaa agaaaatggt ttaaaccaac ttgtctagat
    21121 agttattcat tggtatgata gtttttgata aggaaggtgc tacatgaaaa aaagacagaa
    21181 aaagaaaaac gcatataaac actatatccg ttcgattttt accggttatg aaagaatgct
    21241 tgaagatccc gaattggaac aattgacgtt tacttatcta aacgaagaaa cgcagctaac
    21301 tcgtgatgag catcagcgca ttcatttcac aacaagagat ctgcctagta aataaaaaat
    21361 aagataaagg tcatcggatt cgattctgtc ctatcagatg gaaagactag ttgatcgaaa
    21421 aaaaggctgt accaaatttt ggtgcagcct gttttatgga gcattgcccg ctctttttta
    21481 taacaatttt ttacagaaaa tggtactatt gaagtattaa taagtgaaaa acagatgagt
    21541 aagaggaggc aagtagtatg aaagagccag atacaaatgc aaattatgag ccagacgaac
    21601 tagaggagac gaatgcggat caggatacag gacaagaatc gtcttctttt tacgatatca
    21661 aagaaaaagc aagcatgaat ctttcccaat tattagaaga cttacaggct tttgaaaaag
    21721 ctgtccgcga agaagatatc cctgagatct accgtttata caatggccga ttgaatgaag
    21781 aattaaaaag aagctcaaat gaaaatcacg agatcgatca attgctgatg cgtaagatcc
    21841 atgatcgttt tttacaggaa tttcctttta tggaacaagt agaaaacatc tcgccaacga
    21901 tgagctatta caaaatcggc acttattacc atgatcggcc cacggtcggt attgatgcaa
    21961 gtctgccaga aatttttgtt ttgcctaaga tcgatgaaga gtgggagaaa tattcccaac
    22021 cggagtcaac ggactatgac aaaaaaatca atgagctaga cgcaaaggtg atcactgctc
    22081 agacagaaat tgaacgttta gatgaacaaa taaaagaaat caatcgacaa atgactgatt
    22141 tgaacgacaa taaaggattc ttgaatcgta aaaaaatcga ggaagaaatt caagaattag
    22201 agaagaagaa gcaagtacta tctaatgaaa aattaggctg gcttccttat attgagacgc
    22261 ctgaaacaat ccagcagcaa aaagaagcat tgaagcaaga agcaagagca gaccagcttc
    22321 gtgcagccat cgtagaaaaa gaacaaaggc aaatcagacg ctatttcggt agcaaagagg
    22381 gattcggtca agcaatccat gaattcttga tgaattatct tggcaatgag aatcctaata
    22441 atcaatctaa tgaaggaggt tccgagtatg aatgaacacg atgaagcaga atggacaaaa
    22501 aatgaagaac aaacagaaga tcatgaagaa acgaacactt cattggaaga acaaacaagt
    22561 aatcctctgg atgacacaga agaaatccct atgctagagg aaacaaaaat acacgaaaaa
    22621 gaaaaagtaa ctccgacgaa tacgaatact gcagaaaaca cccatgctta cgaaataact
    22681 gaaaatcccg ggtatttaga aggaaaagag caagatcatc aagatatcgt cagtttgatt
    22741 gaaacagcgg aagcagaatt agcggattta cgtatgagaa aagatttgat cgaatcagat
    22801 tttccacaat tattagaatc atatgatcgt tttatattga atgaagaacc aatctccacg
    22861 atcggaaaga caagcctgat cgaatacttc acgtatgaat tactgaaacc gttgaatgat
    22921 attggtctgg aacggtcaaa ttcagcttat gacacatgga aaacaagaca tttttcgatc
    22981 aattatacgt tgaatggaca aaacgaatta gtcttttcct ttgtattacc gaccatcgat
    23041 caacgatacc aagtggaatc gatgagtctc ctaaacgtat caccagagac aatggaaatc
    23101 aatgtccaag atgaccgggt gctttctttg atccgacact ggtcagtgga tcgagtattc
    23161 tctgcagggc agatcacgat attcaatcac aaattgaatc aattattagc ccatgcaaga
    23221 acacttggtt ttaccgttaa tcagacatta ctagacaata cgaagccact tcgtttgaat
    23281 cttcagagcg aatttgaatt gacgaatgaa gtattggatg atatttttat cgtggcaatg
    23341 aaaaatccat cctacgatat ggaaaagatc aacgaaacta cttatcaagt acgattagat
    23401 aaaggacagt ctttaacgat aacaacaaac gaaaaagatc aaacagtctt gtcgatctca
    23461 tctggagact acccacgatc tgtcattgat ttctttatca attacgaatt cttggtccca
    23521 ttaatggtga gaaagtcctg attggataag ttggattacc agatgtcatt cagataattc
    23581 tgttccaaag gacttgcggc agttatccag aataattgtc acaagtcttt tctgtatgta
    23641 ctaaatggac gtgaataact tgctgatgaa ggagggattt cattaggaat gtccacaaat
    23701 aaaatagcac agcttagctt attgtctgct gcttgtgtag caggtaggat cgcttttcaa
    23761 tttattccga atttccagcc aatgactgct atttttttat ttatagtact ttacttaagc
    23821 ttaaaagatg cgttaattgt catgagtctt tctattgcga tcagcagttt ttattttggt
    23881 gttggaccat gggtcatcgg ccaatggatc agctatactg ttgttctgag tttgttttca
    23941 atcgtctgct tgagaaaaac agtgcaaagg aatctatggt taaagggagt ctgttttttt
    24001 ctggcgggca tggtttacgg aataggtatg accgtttttg atacgctgtt atatcgtttg
    24061 cctcaacctt ggatctatta ccttcaaggg gtgtcgtttg atttgatgca cagtataggc
    24121 aatgttgtgt tctttcttgt ttttctgcca gtcgtcaaac gtttttacaa tcattcagga
    24181 ggaaaaaatg aaaaaaataa tttatagttt gcttgcaatg agtgtcagta tactcatttt
    24241 gacaagttgc agtacaacct atacacaatc ggcttccaac caaaaggagg aagtaaaaac
    24301 atcgcaaaaa gcaacaatca cgttacaaga aaatggtcaa aacttttcgg aaaaagaagt
    24361 gttcttcaaa aaaggcgatg atttactgag tattttgaaa cgaaattttg aagtcaaaga
    24421 agataacggc ttcatcactt cgcttgaagg gcactcacag gatgagaaaa atcaactcta
    24481 ttggatgttt actgtggacg ggaaaagtgc tactactggt gccaaagaga tcaaattgaa
    24541 tgatggacaa tcggtcattt tcaatttgtc taaactataa gtttcataaa aaactgttaa
    24601 agggcgaata ttgccataat tcagtgagtt cagttgatga aagaaggaaa ataacatgga
    24661 aaattttaaa aaaagcggaa tgttttccgt aattgctgct ctaggggcta atattctagt
    24721 tgctatcagc aaatttgtcg gctatgcaat cagtggcagt gccgccatgc taaacgaaag
    24781 catccacagt atcgttgatt gcagcaatca gattttgctg ttattcggtg ataaacaagc
    24841 caataaagga cagagcgagt tgcatcaatt tggtgaagga cgagcaaaat actttttcag
    24901 tacaatcgtc gcaatgatgc ttttcttcgg cggtggggca cttggggtga tggaagcttt
    24961 tgaaaagttg acgcatccat cccatgaagt gggtaatccg atcattgtta tagcaatact
    25021 gttatttggt ttggtaatcg aaggaagttc gttacgcgtg gcaatgaaag aaatcaaaga
    25081 attgaatact gaaaaacttt ccacgatgcg ctttttgcgc gaaagtcgac acagtgaaat
    25141 actgattatt tttacggaag acttgtgtgc tgtaatcggt ttggtcttgg ctttagcagg
    25201 aacaatattg acttatgcaa ccgggattgc tgcatttgat gcgatcagcg gattgctgat
    25261 cggtttcttg ctgatgggag ccgccatttt cctagcaaaa gaattttata gtctgatcat
    25321 cggtgaaagc gtgacagcaa gcgatttatc aaaaatcaag ttagcttttg aacgtcctga
    25381 gatcagtcgg ctgatcgata taaaaacagt tcatttaagt ccaacggaga ttttagttgc
    25441 agcaaaagca gatatcgttg gtaacaaaga gaatgaagct tactcggtca tcaatgatat
    25501 tgaaaaaaat atgcgtcagt ctcttcctga caagaagatg tatatataca ttgaaacaga
    25561 taaatatgac ccaaattatt ctcgtaaata aaacgtttat tcatgaattg aagcaaaaat
    25621 gagaaaaata taatcttgtt tttaaataaa acggctacaa tttagcgaat ttatgttaca
    25681 atgagtccgc tgtttatttg ttgtaattaa aggagatatt ttaatgaaca aaaagaaaag
    25741 tgcgccatgg cttcaagctt tgcatgcagt gatgccactt tgtataagct atataccagt
    25801 aggattagct tgcggagtat tgttgcaaaa agttggattt gatcctctct tatcaggact
    25861 gttatcgatt ctggtctttt ccggtggcgc gcagttttta gttgcatcta tgcttacgac
    25921 gcaagcatca tttgcaacga cattattgat ggttttcttt ttagaattac gctatacatt
    25981 attaggagca agtcttgccg gttttatgaa aaaagaaaag cggacgtttt tggctgtctt
    26041 ttctcaatca ctgaatgatg aaaactatgc ggtgaactac ttaaagtttt caactgaccc
    26101 ttcctggaat aaaagaaagg ctttatatgt caattggttc tcaatgactg catgggccgg
    26161 tagcaatatg atcggtaatt ttttcggctc ggtgattcga gtagatgctg accttgtcca
    26221 ttttgctttg acggccatgt tcattttcat gtttatcatg cagatgaaaa gcgcactact
    26281 gatctttaca ggtttattct caggcgtatt aggggtcgta ttcatggtat tattccaaaa
    26341 tactttcgga ttgattgcag caacagtcat tgcttcattt gccggattta tgctggagaa
    26401 ggcattcaaa aaagaaaaag ctaagaaact aagagaccgc ggtaaagatg tcaatgagcc
    26461 gctcttcaac ttcccggaac aggaggccaa tcaccatgac taaactatat ttgctacttt
    26521 tagttgcttg tctgttcatc gtggcatata tcccgcgctt gttcccgatg ctttatttta
    26581 ctcatcgaaa agtgccatcc tggttcagtg actggatgaa atatgtaccg gtggcattat
    26641 ttgcggcgtt agcttttaaa gatgttttca ttactcatga acatctggat attgcttgga
    26701 atatcaaaat agctgcaatg attctagtag caggcgtggc ttacaaaaca cgttcgatgg
    26761 cgttgtcagt tttgacagga cttgcgtctg tctttttgct gtctatgctt taaactgttt
    26821 tattttatta aaaacagaga ttgcgacata agttgttcaa actgatctat ccgaactgca
    26881 tttgcaacag tcaattctgg atgcaagttt attcgtaggg ataaaaaaga ttagtgttgg
    26941 cttatgatgc aagctctttt ttattttagg aattagagag ggatttgtcc ttctatgatt
    27001 ttttgctata atagggaaga tgtttatttt atgaaagaat agttgaggga atttaaatga
    27061 ataaaaaatt gatgcaagga acattttggc taacctttgc taatcttcta tgtaaagttt
    27121 taggggtagt ctatttgatt ccctggctaa gtatgatggg gaacaatcaa gatggtatgc
    27181 ttgctacgac attgtataat gttggctatc ttccttatgg attgttcctg atgcttggta
    27241 cagtcggatt tccaaatgcg attgcaaaaa aagtagctgt agccacaaaa gaaggagata
    27301 acgctgcttg tcggctgatt tttagaagta cgatcaatat catgtttgtc atcggtatcg
    27361 cctctgctgc actgatgtat ttatttgctc ctttactagc cggaatcagt ccgattgcta
    27421 acgttaataa tgggatacta gctatcagaa gtttatgccc atctttgatt gctatcccaa
    27481 ttcttagtgc aatgagagga tatttccaag gaaaaaatga tctgcggcct tatggaactt
    27541 ctttgattat cgaacaggct gtgcgagtga tcgttatctt ggctggtact tattacttgc
    27601 gcgtattgac tgacggaacc atattagaag ctgtattgat cagtacagtc gcttctttct
    27661 tcggtgggtt agctgcgatt atccatatgt atatcgtcgg acgcagaaaa gacttcttcg
    27721 aacttaaaga ttttttgatt tccagccgtt atttcgaaag agaaaaccga tctgcctctg
    27781 tctctatcat tcgggaaaca ctaccgttta tttttgtcgg ctcagtcatt actatcgttc
    27841 aaatgatcga ccaagtaacg atgaaaccac tgcttcactt tttccgtcca gagatcgcag
    27901 atcagcaact ggaattctta ttcagccgtg cttctgtcaa tccaaataaa ttgacattga
    27961 tcctgatctc catggtagga acagtagcta taagcagctt gccaatatta agcacgatga
    28021 agaaaaaaga tcggatacaa atcgaaaaaa cagtaggaga tagtttttcg attgcgttat
    28081 tgattcttct tccttcattg actggaatgt ctttattagc tggaccacta tacacattgt
    28141 tttttggcta tgatcctgaa agtgtcggat atttccaaat ggctttgcta gcttctttgt
    28201 ttttctcttt attcacgatc ctatctacga tgcttcaatc tttgaatcac catcgttttg
    28261 cgatccgatt aactgtagaa gcaattatcc tgaaagtcat cttccaagta atcggattag
    28321 gattagttgg cggatacggg atgagcttat caaatggctt agcattcggt attgtctttg
    28381 ttcgcggcta tcactttatg tgcaaagaat accgaatagc acctttagca aagatcagca
    28441 attttttctt aaaaactttc cgctccaccc tgattatgct tgcagtatgt tttgccgttt
    28501 tctttttgct gaatcagcga ttgtcaatgg aatcaaaaag ctatgcaatg atttattgtg
    28561 tggctgtagg aagtattggc ggcttagtat ttttattttc tcaattcgga aaaaatgggt
    28621 ttcgaatgtt gaaaaatgtt aaacatcata gcagaagcaa agaataggtt aactaatcgt
    28681 tttttgctgt cacttgaaaa acggcaactc gtatgattac gcttgtcgtt tttctatttt
    28741 ccaattttag tttcatatct aatcttactt atgatatagt tataaggtct ggaaaaattc
    28801 tttgaaacga ggaaattaaa cacatgaaac ttgcagtagt tacagatagt tcggcatatc
    28861 tgccggaacg tatcaagaac catcccgact tattcgttat tccaatccct ttgattatgg
    28921 atgggaaaat ttataacgaa ggaatcgata tcgaagcgga tgaatattat ggacttttaa
    28981 aaaacagtaa agattttcct actacttcac aacctgtcgt aggggaagtt ttgggtttat
    29041 atgaggaatt gaaagagaaa gggtatgaca cgattttaag tatccatctt tcttcaggga
    29101 tttctggctt tgtcaacaca ttatttgcga tgaaagatga catcagcgga gtaacggtca
    29161 ttccttatga ctctaagatc actagtatgc cgatgggaca catggtagaa gctgccttag
    29221 acttaaatga tgaaggtcag tcccttgatg aaatacttgc acatatcgat cgaatccgag
    29281 ataataccta cgcttatctg attgtagatg atttgaacaa tttagtacga ggaggacgtt
    29341 tgacaaatgg tgcagcgctg attggcagct tattaaaaat caaaccgatc ctgacatttt
    29401 ctgaagggaa aattgtttta ttcgaaaaaa tccgttcaag taaaaaagca tttgctcgag
    29461 ctgaagaaat tattggtaga agaaataacg aaatacaacc gccagtcaaa ctttacgtga
    29521 tacatgcaaa taatttagaa gtagcgattg cggagaaaga gaaattgcag aaaaaatatc
    29581 caaatgcaga aatcgaaatt ggtcatttcg gaccagtcat tggtacacat ttaggtgaaa
    29641 aagccatcgg cattgccatt tcagcgcaat aattcctttt attcaaaaaa cataccaaaa
    29701 atattccaac atcatcttgg actttctaca tgttactaat gagcgtgtaa aagaacgaga
    29761 tggtgttttt atttctatca atgaagctct ttttctttgc aatcctcact tcaatcctct
    29821 ataatgtcgc atatagttta gtaaatgagt aaactactaa tttacttatt tactaaaaat
    29881 aaaaggatga ggagttaaaa taatggaaat accaacaaat ttaaaacata aaccagtaat
    29941 cgttgtagaa gactatgata aagttgatgg aagaaatgca ttaaatacgg atgcaaaagg
    30001 gctttcactg ggccttgctc agtggaatga tcgtggaaaa gtcgatatct caggcaaggt
    30061 atggcgacat actggagaaa aatggtcacg acagtcggaa gaattaccaa tcacacgtat
    30121 tttagattta gcgatcttag ctgcacaagg aagtttatac ttccaagatg cttatcgtta
    30181 tgaaaaattt tatgatccag aaaatccagt cgtagacatc attggattac aagggaaccg
    30241 aatgacggta gaagtagata ccaaaaatcc aaagatcgat gaagacatca ttttgtatta
    30301 cgatacacta caaaaagacg gagaactgat tggggaacga ttccgtattt taaaacgtct
    30361 tttagatgag ctaggatatt aatagacaga gatgatcaaa aggggaagag aagcatggag
    30421 aatttctcac taacagaaaa ccgaaccttt tcacggctag aaaagcaaat gatctggaag
    30481 aaaccgaaaa gccatcggac aagtgcagaa gaatggcgga tcgcctccga aatcaaaggg
    30541 aattggcaag atcctgaaat gaaaatcagt aacgtacttt tggaaggaga tgccgggtcg
    30601 gggaagacac aattagccaa agcactatct gctgatctgc aacttcccta tacaaaagtg
    30661 acctgttttg cagatatgga caaatcagat gttttcggag ccttattacc tgtagtagat
    30721 tctaataagg aacaagacca agaattacta gaagctattt accaaacaga tacacttgaa
    30781 gctgtactga cactgatcca gaaccattac ggcattgatc ctttttctgc taaagaaaaa
    30841 ttagcagagc tagttcaaag gatcgaagct gattatccag atgcaatcca ttacagctat
    30901 tacccttctg aaatcgttcg agcgattgaa aaaggatatt tattagagat tcaagagccg
    30961 actgtcatcc gagatgcctc tgttcttgtg gcacttaact cagcgctcga accaaatggg
    31021 atgttgaatt taccgacagg aatcattcgt cgccatccag attgcgtcat tgtgatcact
    31081 acaaatcgaa attaccaagg aaatcgccca ttaaatgaat ctttaagaga tcggatgcaa
    31141 catgcggaaa aaatggatct tcctgcctta gaagtcatgg cagaacgtgc gatggcgaaa
    31201 actatgatcc aaaaacaaga acttctctta aagatggcag agattatccg tttgttggat
    31261 gaaactgcaa aagctaacgc catcaaaggt gtagcaggaa tgcgttctta tttttattgg
    31321 gcaaatacct ataagcaagg acaagattta ctccagtcga tttatccaaa agttttgtat
    31381 aaattatcca ctgattcaga tgaattggca attcttgaac aagctttgtc tgacagtgga
    31441 ttgctactgg aacttcagga catattgaga aaagaaaaat ggggtcatcc tcaatctgag
    31501 catacaaaag gaagaaccat tagcgccgaa gaagcaaatg aacgaaacat cactgaaaat
    31561 gctgaagaaa ttctgcgctt agatgaaaag aaatcgttgt ctgctgaaga accaaatgag
    31621 ggagaagaga aacaagaaga aacaatagaa aaaaacgaga ttcctcctca aatgcaaaaa
    31681 gaacgcagta gcgatatcga aggaaaaaat caaaaagaac aacaaacagg agatgattct
    31741 caagaaatgt ctgcttctga catggaagca catgataagg aaatcaagaa gcaactgaat
    31801 aaagaagcgc gacaaatcat gaaggaaacg attcatgaaa aagaaggtct catcgttcac
    31861 cgaccagctt tccaaggaaa aacgccggaa gcacgtgagc tacacatgca agtaatgcca
    31921 atagtagaat cacttagccg gcaaatttta gagttactgg ataatgaaca aacagagacg
    31981 taccaaaaag gaaaatacga aggtcagcgg ttcaatgcaa gcaaagtagc atatggtgat
    32041 ttgagaaatt ttgacaaaaa gaacccgcca catgagcaac cttctttagc ggtagctgta
    32101 cggatcgatg aatctgggtc aatgatacgg gatgatcgga tcgaagcggc aaaaaaagca
    32161 gcgattgcca ttgccgaatt ttctaagaaa gtcgatatcc cattgttgat ttacggagat
    32221 acagcagacc gttcgtcaag agaaaagact tctttgtttt cttataaaga atttgaagac
    32281 ggatttcaat ggttaaatga aaaattagtc actatgaaac caaggcaaaa caatcgtgat
    32341 ggtgctgcac ttcgtttagc agcagaaaaa ttaaacagac aatccgcaac aaccaaactg
    32401 ttgcttaata ttagtgacgg tcagccaaaa gcgttgccgg attatacagg caaaaaagca
    32461 aaagaagata tccagtctgt tttgaaagaa tatgaacgtc aaggaatcct atttgtctcc
    32521 gcagctattg gccaagacaa agaagaaatc aagtcgatct acggtgaaag tcgttttgta
    32581 gatattactg acttgaatga atttcccaag caaatgattc aactgattgc ccgctatcta
    32641 tgataaaata aagctcaacg aacgcactta gcagattcgt tgagcttttc gtttctagtt
    32701 accggtaaca aggatacttc taaaatagaa tcggttataa tcaagaggga ccgttaaagg
    32761 agtgaaacga tatgatacaa gaacaaaaat ggtggaaaga agcagtaggc tatcaaatct
    32821 atcctgctag tttcaaagat agcaatggcg atggtcaagg agacatcaat gggatccgtg
    32881 aaaaacttaa ttatttgaaa gatcttggta tcggctttat ctggatcaat ccgatctatc
    32941 aatctccatt tgtcgataat ggttatgacg taagtgacta tcaagatata gaagagagat
    33001 tcggaacgat ggaagatttt gatttattgc taaaagaagc acatgaatta gggatcaaag
    33061 tgattatgga tcttgtcatc aaccatagtt cggatcagca tcaatggttt gaagaatcga
    33121 aaaaatctaa agaaagcccg tatcgcgatt attacatttg ggtcgacggg gtagatggca
    33181 aagaaccgaa taattggaca tcgattttcg gcggttctgc ttgggagtat tctcatgaaa
    33241 ctggacagta ttatctgcat gtttttgcaa aagaacaacc agacttaaat tgggaaagcg
    33301 agaaattgaa agaagaacta ttcaatatga tccgatggtg gttggataaa gggatagatg
    33361 gatttcgttt agatgcgatt tctcatgtaa aaaaagatga atattcagta aaagccacag
    33421 agaacccttt ctcacccttt caaaatgtct caggaatcga agaacatttg accgatttga
    33481 aacatgtttt tgaagagtac gatatcatga ctgtcggaga agcaagtggt gtcactgcag
    33541 aagaaggacc acaatgggta gggaaagacg gttatttcga tatgatattc gaatttgatc
    33601 atatccatat ctggcagcaa gaaaaagaag ggcaattaga tgtccttaaa ttgaaacttg
    33661 cattaagcgc ttggcaaact tcattggatg gtatcggatg gaacgcttta tatatggaaa
    33721 accatgatgt tcctcgtgcc gtttcagtgt ttggagatac tcgtcccgat ttttgggcta
    33781 tgtctgcaaa agcaatcgct atgatgtatt tctttttgca aggtacgcca tttatttatc
    33841 aaggacagga aatcggaatg acgaatatgc cctttgaatc gatcgatcaa gttgatgcag
    33901 tagattcgaa aagactttat aaaaggctgc ttgcggaagg taagacaaga gaagaagcat
    33961 tggatatcat tcgtgaaaca acgagagaca acagcaggac acccatgcaa tggacttcgg
    34021 aacaatatgc tggtttttct acacatgaac cttggctgat cactaatcca aataccaaaa
    34081 cgatcaatgt agaacaacaa gaatatgaac cagagtcggt cctgcaattc tataagaaca
    34141 tgatccgcat tagacaaacc aataaaggtc tgatatacgg ttcttataaa gaatatcttc
    34201 atgaacatcc acaactttat gtctatgaaa gatatttaga agatgaacaa tatcttatta
    34261 tggtaaactt aacagaatca cttgctgact atgaacttcc aaaagaagca gatcagtcct
    34321 ggacattact cttgtcaaat tcctctagcg gagaatttga agctaaaggc atactagcac
    34381 cttatgaagc tcggttatat aaaacaaaca agtaaaactt cctcgttaaa gttcattagt
    34441 tggactttgc gaggaagttt ttcagattgc tctgtcaatt actcatttca ataattcgct
    34501 ctaggaccac cgatatattt aggacgagag cgaagggctg tcacgtgagc ttgtccaagg
    34561 gttttcaaac gaggtctgac aggtacttgg acatgtttga tatgcatacc gattgatgtg
    34621 tcaccgatat cgataccggc ttgtccaact acgtgttcca cttcgacagg atcattgaac
    34681 tggtcaaaag cagcaacaga acaagcacct ccagcatgta gtgcaggaac aacagagaca
    34741 atttcgaaat tttttgcttc tgccactgtt cgttctacta ctaatgctcg gttcaaatgt
    34801 tcacaacctt ggacagctag cgcaatttct ttaggatcca acaactcttt taacgtacgg
    34861 atgatccatt gaccaacttc cgcactggaa ttttttccaa tatgtcctcc aacgacttcg
    34921 cttgtgctgc atcctaaaac aaaaagatca ccttttttca agtgtgcctc agccaatatg
    34981 tcattaacta tttcagtcaa ttggtctttt aattcttttt ctgacaactt cattttctaa
    35041 aaccttcttt ttcaattaat attgcttccg tgcttgaata cgttgaagac ttgcagttat
    35101 aggaaaggca agtcccattc caatcagatt ttggaagatg tttcctggta tagaagccac
    35161 tccagccggc caatcatata aaatccaacc ggcgatacca tagccgatga tcataactaa
    35221 gcttcctaat aaaagcccta atccccacat acgagtagaa gatttgctga aagaaccagc
    35281 aacatatcct tgtaacccgt ggatcactaa tgaaaaaact gcccactgcg gatatcctga
    35341 aatcaaatcg atcaatagac cactggaagc accaacaact aatccacccg ttggaccata
    35401 aagaaaagca gcggtataga tcccggcctc gcataatgtc acaaatccat tcgtagccgg
    35461 tacagggatc aaaattgtta atgaaagggc aactgtcaac gcaatcagca tagcatagat
    35521 cgttaattgc ttagttttca tttctcattc ctcctttttg aataccgcca gaccagacac
    35581 ttccggtatg atcgttcatc agcacgccat tagaaataca atgggcaaca aattttttac
    35641 tttctgctac tgctttggta aaatctgccc ctaacacaag attcgctgtt attgcagaag
    35701 aaaaggcaca accggccccg tttactgttg tagtgtcgat ttttttatga gaaaatacct
    35761 cataatgatc aattgaatag agaagatcca cagcttcatc tccagccatc cttgtgccgc
    35821 ctttgatcac aatgtttttt gttcctgaag cagtgagttc tttagcgaga tggatcattt
    35881 ctgttaacga agagggaaga gcttgaccag aaagtaaagc agcttctgcc aaattaggcg
    35941 taatcatcgt aacaagtgga aaaagttctt cgatgagctg cgaaatatac aattgattga
    36001 tcacagcttc agtttctttg aatgccaaaa cagggtctaa aatgattggg atattttgtt
    36061 ttgtttttat gaagtctcga acaaccatga ttgcttcact tgaattcaat aacccaattt
    36121 tgataccatc taatgaagtc attttatcaa tcgaaactaa ctgtcgttta agcaattcca
    36181 aagatataga ttccagcata aatcgctcat taatatctag tgcccctata gaagtcaagg
    36241 cgcttagtcc gaatagacca aaattctcaa aagtttttaa atctgtttgg attcctccac
    36301 cagcaaatgg atcagaaccg ccaattgtca agattctttt cataacattt tcctccatga
    36361 ataagagtat aacgaaattt tcaaaaaaga aaaacagcca attggcatat ttttatctca
    36421 tccaatttaa aaaaacaaaa agaaaagaaa gaccaaaatg gatctttctt tccttaaata
    36481 gttaggactt ttgtgatttt aattctttct cgatttgaag ccgttgcact ttcattgtag
    36541 ctgttcgcgg gattgcatca aaatcacgga tgatagggac gttcaagcga ggaagttcat
    36601 ggacttgctc ccaccatcga ttccaatcca tttctttatc aggagctaaa gcaataatcg
    36661 gttgtggaga atgattttta tcccttacaa tcactacttc tgccaaaaaa tctaacgaat
    36721 ctaataaaaa gtcttcaata gctaatgtac tattgatcgt ttcgatcaaa tccacttgcc
    36781 gatctttcaa aaataggtgg ccatgcttat ccataaaacc gtaatctccg ctatcccacc
    36841 aatcgccata aacattttcc tggaaccgtg catcttcctt gtaataagtc aaagcccgtc
    36901 ctttagacag taattgtata tgaccatctg tgttttcagg taggacattc ccaactgaat
    36961 ctgtaatccg agcgcttgtc atgtcttcca gtccaacgcc catatctctt gcatcacttg
    37021 ttttcaaact ctctagtgta tgagccttaa gaatcattgg tccgcattca ctttggccat
    37081 atacttgaag aaataccgca tcctgtgcca tcgacgttcg caaaaatgtc ttcattgtct
    37141 ggttgtttat agcatcaaaa gtggagtgat agtatcggat acccgaaaaa gcttctggat
    37201 gctccttagc agtaaaacgc cactgaacaa agttattcgg atgggtctct agtgcaattg
    37261 gccggtgagc ttccaacata tgaacaactt ttgaactttg tgcgtttgct aaaggcatca
    37321 taggaaatcc catggacatc aaagaagaga taccaatatt gaatctggaa tgcactggag
    37381 agatgtgaaa agcgattaat ttcttttccg aaatttttgt gaaaactgtt ttttgccatt
    37441 tcgtccgcca tcccatagaa tgagcagaat gacaaataag tttagggata ccagttgtac
    37501 cagaagtatg ggtcatataa gaaatttcat ttttgtctaa aaatgattga gaaacagaca
    37561 aagcaggttg ttccattaaa taaagaatag g
//
LOCUS       DAFELK010000025        36705 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFELK010000025
VERSION     DAFELK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.026"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..299
                     /locus_tag="LP433_001484"
     CDS             <1..299
                     /locus_tag="LP433_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2005654.1"
                     /translation="GLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENR
                     KVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(723..893)
                     /locus_tag="LP433_001485"
     CDS             complement(723..893)
                     /locus_tag="LP433_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2005655.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1087..1266)
                     /locus_tag="LP433_001486"
     CDS             complement(1087..1266)
                     /locus_tag="LP433_001486"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005656.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1276..1500)
                     /locus_tag="LP433_001487"
     CDS             complement(1276..1500)
                     /locus_tag="LP433_001487"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005657.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            1653..2765
                     /locus_tag="LP433_001488"
     CDS             1653..2765
                     /locus_tag="LP433_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2005658.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2843..3136)
                     /locus_tag="LP433_001489"
     CDS             complement(2843..3136)
                     /locus_tag="LP433_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBL2005659.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3304..3618
                     /locus_tag="LP433_001490"
     CDS             3304..3618
                     /locus_tag="LP433_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBL2005660.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3639..5618
                     /locus_tag="LP433_001491"
     CDS             3639..5618
                     /locus_tag="LP433_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2005661.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5631..5957
                     /locus_tag="LP433_001492"
     CDS             5631..5957
                     /locus_tag="LP433_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBL2005662.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5973..6491
                     /locus_tag="LP433_001493"
     CDS             5973..6491
                     /locus_tag="LP433_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005663.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6491..7843
                     /gene="celB"
                     /locus_tag="LP433_001494"
     CDS             6491..7843
                     /gene="celB"
                     /locus_tag="LP433_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL2005664.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7927..9432)
                     /locus_tag="LP433_001495"
     CDS             complement(7927..9432)
                     /locus_tag="LP433_001495"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBL2005665.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9524..10114)
                     /locus_tag="LP433_001496"
     CDS             complement(9524..10114)
                     /locus_tag="LP433_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2005666.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10293..11939
                     /locus_tag="LP433_001497"
     CDS             10293..11939
                     /locus_tag="LP433_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2005667.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11988..12707
                     /locus_tag="LP433_001498"
     CDS             11988..12707
                     /locus_tag="LP433_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL2005668.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13186..14133
                     /locus_tag="LP433_001499"
     CDS             13186..14133
                     /locus_tag="LP433_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2005669.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14145..15065
                     /locus_tag="LP433_001500"
     CDS             14145..15065
                     /locus_tag="LP433_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2005670.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15106..16563
                     /locus_tag="LP433_001501"
     CDS             15106..16563
                     /locus_tag="LP433_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2005671.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16908..17522
                     /locus_tag="LP433_001502"
     CDS             16908..17522
                     /locus_tag="LP433_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL2005672.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17515..19239
                     /locus_tag="LP433_001503"
     CDS             17515..19239
                     /locus_tag="LP433_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2005673.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19236..20687
                     /locus_tag="LP433_001504"
     CDS             19236..20687
                     /locus_tag="LP433_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2005674.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21160..23313)
                     /locus_tag="LP433_001505"
     CDS             complement(21160..23313)
                     /locus_tag="LP433_001505"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBL2005675.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23315..24361)
                     /locus_tag="LP433_001506"
     CDS             complement(23315..24361)
                     /locus_tag="LP433_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2005676.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24511..25800
                     /locus_tag="LP433_001507"
     CDS             24511..25800
                     /locus_tag="LP433_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBL2005677.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            25813..28515
                     /locus_tag="LP433_001508"
     CDS             25813..28515
                     /locus_tag="LP433_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBL2005678.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28500..29357
                     /locus_tag="LP433_001509"
     CDS             28500..29357
                     /locus_tag="LP433_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2005679.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29428..30327)
                     /locus_tag="LP433_001510"
     CDS             complement(29428..30327)
                     /locus_tag="LP433_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL2005680.1"
                     /translation="MVQLVCNCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            30496..32667
                     /locus_tag="LP433_001511"
     CDS             30496..32667
                     /locus_tag="LP433_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL2005681.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            32735..33076
                     /locus_tag="LP433_001512"
     CDS             32735..33076
                     /locus_tag="LP433_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL2005682.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33352..35106)
                     /locus_tag="LP433_001513"
     CDS             complement(33352..35106)
                     /locus_tag="LP433_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005683.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35117..35953)
                     /locus_tag="LP433_001514"
     CDS             complement(35117..35953)
                     /locus_tag="LP433_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL2005684.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(35955..36638)
                     /locus_tag="LP433_001515"
     CDS             complement(35955..36638)
                     /locus_tag="LP433_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBL2005685.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11842 a         6447 c         7480 g        10936 t
ORIGIN      
        1 atggcttagc accaggagca tatcagctgg tagaaactca agcgccaacg gggtatgaat
       61 tggatgcgac accagtaact ttcaagatcg aaaaagaaca agaagtggcg atctttttaa
      121 caaaagagaa tagaaaagtt gctgatagct cagatataag aggaaacaat ccaacaagca
      181 gtggaaataa gcatcttcca aaaactggag aaaccatcat tagccagttt atattgtcaa
      241 tattgggtgt gctacttgtt ttcatcagta taaaatttag aaagaaacga aatatatgag
      301 ctaaaataaa aaattgaata agcatagttt ttaaaatcaa ctagtaccca tcaattgaat
      361 ggaaactacc gattttagaa ggggtataca aacaaatatt agtatcggag tagagaaggt
      421 tgaacccaac cagtaaataa gtaaagacaa ttttgtgctg cgttgagaag tgaaaaataa
      481 acctttgtag taatactagt taataaaaaa tatacaaaaa cactgcgaaa atcattcttg
      541 agtttcgcag tgttttttgc ctaatgactc aagtttattg ggtaatactt tgattttctt
      601 tctacaaata atcagcgatc agttgtaatt ttttctctag ttttaatggc tctttgtcaa
      661 taaggagaaa aacaagtcgg gtcttttgtc tcggaaagct tcaaccaact cgtgaataaa
      721 ggttacgcct ccttgaaagg cgtggaaaaa ccaagtaatc gatcaatcac caatttcgca
      781 tttggtagaa catgtttggt gagctgaaag taggtggcgt tcatgtctgt aactaagaat
      841 tctatttctt taggattagt gcagctaagg aaatagtttg ttaatcgagg aattttttgt
      901 gtaggtaaat tttctcgatt aatttttctg tctcgccatc cgcggaaata aaactcagtt
      961 tatcctcaac ggaaacgtga gaacgaaatt cacaaccctc aacactcaag acagaattct
     1021 tttggaagac tttggtaaat agcttctcaa ctctttcaat gtgcgaataa cggttgtcaa
     1081 agatacctaa caacttttcg aaataaaaaa taacgacact ttttcagtca gtaaagaagt
     1141 gattttatgt ctgacatgat ttgaaatcga gtgccttgga cggataaaat aactttgagc
     1201 gttccaatgg cttcgacagt ttttacaggt atagcgctgc ttttttaggc gtataaccat
     1261 tggcatatga ttatattatt caaagtggac aatggtttcc ttcttcttgt ttttcaccac
     1321 cattaatttc ctatttccat ctaccacagc agaaccacaa tttctacaga cacatggagc
     1381 agggaagaga actgcagcaa cgatcaatgt ttttttcttc tgtaaggttt cgtaagagac
     1441 ctctgtaatc atcaaatttt tgtctattga tctcagaatt tttttgatag aaccattcat
     1501 aaagcatatc gttctctcag ttgtttattt tgtggtgatt taatcataca agaaaacgat
     1561 atgttttttt ataaaaacat gaataggaaa aatagttgac aagaaaatga caacgccata
     1621 tgatgttcca tagtatttac aacctgtcat agatgactgt aaaaaataaa agtaaaaaga
     1681 aaggacgaca acaggtggat ttttatcagt ctctacaact agatccgttt attttaaaac
     1741 aaaaaatacg agaagcagct tctaaaaaag aaaagtgcat gtatatttgt tcattgtttt
     1801 tacgatcatt attcatcgta ttgtttgcca tttgttttat cattataatt acaacattat
     1861 ttgaatcgaa gcataaacca tacgctgtgg ttttattctg tatgttgatg agtattcgtt
     1921 ttgttgactt tggttataag atttcccatt cgatcatagg tttagcaatc gtcatgttct
     1981 cactattagt agcaccgtat gtccagctga tcaaatggtc agttatgggc atgttgattc
     2041 attttatttt actaagcagc atattaatgg caaccgctag tgatcccaaa atggggaatg
     2101 cttctttgta cggcttttca tatctcttta ttgtttattc gttacctaaa gattcgttga
     2161 acaagaattt ctttacacaa acaagtagct tattattttt gtttttttgt tggttttcag
     2221 ttcttcttta cagaaaacat cgagaaaaga acaaagacaa aagcttgttt aaagagattt
     2281 ttttgaaagg catgtattcg caggaaaaaa tttggatgct catctatgca tttggcatta
     2341 gtcttttgat cgttgcagga gagtatgtcc cttttcagcg attgatgtgg gcagggtttg
     2401 cattttcttc tattgtatct agctatggat tgatgtcgat tggtttcaaa gaacgagcag
     2461 tagaccgaat cattggctca ttgattggat gtgttttatt tattggtatc agccaattta
     2521 ttccttttaa ctgggtcggt atattaggtg gtctagcttt aggtgtttgt tctacctata
     2581 gatataaaac agtttttaat tcttttggtg ctttggcaat cactgccagt ttattcgggg
     2641 ttccaggagc agtaacgatc cgcatttttg agaatatcct tggggtatgt ttaggaatca
     2701 tgtatattgg ggtgactgaa atacttatcc gaaaaataag agaaaaacac ggtttgaatc
     2761 attagatgag atcgaataaa aaataaggaa aaagtgaaga tacacatgga tgataaattg
     2821 ctatcattcc atgtgtatct ttttacggta aatcagtgaa acgttcgact ttcattttta
     2881 atttatactt tttacggagt tcgtttattt gagccatcat ttcggatttg tgatgctttt
     2941 cgattgcttc ttcatctttc caacggtcga tcagtaaaag agattctgga tcttctagtg
     3001 gaaagtaata gtcatatttc tcgtttcctt cttctgcacg aatcgctttg acaatgtttc
     3061 tttcgaccat ttcttctgca aattttctgg cttgtccatt tgtacttgta tacaaaatat
     3121 tcactgtgat actcactaaa tcccctcctg aaaaaattct atcactagta tatcacggtg
     3181 ccagaaatta ttattcaaga tatgatacac attttttccg caatgctacg gaaatatata
     3241 ttttgaatag aaaacgctta caagatatgc ttggtttata aaaataaaag gagtgattga
     3301 tttatgaaaa aagcattgat tatttgtgcg gcaggaatgt catcctcgat gatggcctca
     3361 aagacaacgg atttctttaa gcaaaaaaga gaagaggtac tcgtagatgc agtttcagct
     3421 acagaaggcg ataatatgat taagaatagt gattttgatt tatttctgat cagcccgcaa
     3481 acgacgatgt ttttggataa attcaaaaaa ttaggagaat ctgttggaaa gcctgttgtt
     3541 agtatccctt tccaagcgta tgtcccaatc cctacaggca tccagaagtt agcagaggtg
     3601 atcgaagaga acatatgatg gaataggagt ggatgataat gaaacagaag gaaaaattgc
     3661 tgttgagata tttgattgat cacaagaagg agtatgtcac cagtcaacgt ttagcttctg
     3721 aattgttatt atctgatcgg acaatccgta attacttgca gcggatcaaa gagttagtag
     3781 aaaaaaacgg aggtaagatc attgctaaac caggttatgg ctaccaactg catattttac
     3841 aaagactgac atttgacttg tttttgagtc ggcaagaaat agtacctgga tatgctagag
     3901 aaccgcaagg attttatgag tccgaagatc gacaaaagta tatattgaac caattgcttt
     3961 tggaagatgc cattcttttt atggatgatt tggcagaaga gctttatatc agtcgttcca
     4021 gtttgacaaa ggacatgcaa gaaatcaagg agcgattgat tccatattca ctaaaaatcg
     4081 tttctaagca tggtcaaggg acatggatcg aaggggaaga aagaaatcga cggcatttta
     4141 tcatggatac tttttttgga aaccattatg gaaattcatt gaaagaatat ttagggcaaa
     4201 gccgtttttt cccagacatc agttttgaag agctagtcat tatcattctc gatgaaacaa
     4261 gagaagctaa gttaaaagtt tcggatttta tcatacagaa tctgacttta cacttggctt
     4321 tggggatcaa acggctccga gaagggtttg aaatcaagga attaggcatc gaacaagaag
     4381 tttctaagcg agtagagtat caagtggcgc agcggatcgt tcaacgtatt gaggtaatcg
     4441 caggtgtatc gtttcccgaa gaagaaattg cttatttgac attacatctc atggctaagt
     4501 cgaatcacaa agaaaatcaa aatgatcagg aactatcaaa ggaattagcg aaagttctga
     4561 aaagattgtc tcaggaattt catttttcat tagtagagga tctccagctt ttcaatggac
     4621 tactcgatca tttgtcaccg atgatgattc gattgagccg aggtattcgc attgagaacc
     4681 cattgactga ggagataaag aaagaaaatc ccaaagtctt tgacgcagta aaaaggcatt
     4741 tcagcaacat gccggctttg aaaaactata ccatcaatga agatgaatgg gcctatttgg
     4801 ctttgcatct catggcggca ttggaaaaag aaagagctgc gcataaacta catgcattga
     4861 ttatctgtgc aacgggttac ggcagtgccc aactattaaa gaatcgcgta gtcagtgaat
     4921 tcggtaaaaa tattacagtg gtaagtgtaa aaggctatta tgagatcaat gaaacaactt
     4981 taaaaggaat cgacctgatt atttcttcta ttgatctttc gacaatgttt ttcaaaattc
     5041 cagttttaca tgtcagtatt tttttgaatg aagatgatgt tcgtaaaata cgaaaggtag
     5101 ttggagaatc tataccctat cattcctcag atagaccgat accagcattt tctctacagc
     5161 aaaaaaagca gatttacacc gaacagttgt ctgaaaaatt tttcaagact tatacgtacg
     5221 aaccgaaaaa ggaagaaatt cttcatgatt tgctgcaaaa gctgagcata aatgaagaag
     5281 aaggatatat aagagaaatg cgaaagcaga tccagcaacg tgaaaatatg ggacaaatca
     5341 tattcagtga tacagtggca gtcccacatc ccgctgttcc agttggaatc gaaacaaagg
     5401 tagccgttgc attgattcct tctgggatgc agtgggatca atatcaagaa attcattttg
     5461 tttttttagt ttcgccttct tatgtcgaaa atgaaggaat tacggtcgtg actaaagcaa
     5521 tcgttaggtt agttgaccag ctaaaagtac agcaggaaat cttagctgaa cctatttttg
     5581 agaatttcag cagtaaattt atcaaactga tcgaataagg aggaaaacag atggctgaaa
     5641 aaataaacag tgaaacacta caagtgactt cttttgatat cattttccat agcggaaatg
     5701 cacggacact gatacatgaa gcatttcgct cgatgcgtaa agagatgttt gaagaagtag
     5761 aagagaagtt gcgacaagca aatgaagaga ttcttcatgc gcatcagtca caaactcaac
     5821 ttctgaaaga atatgccagc gggacaaaaa tagaaatgga aattatcatg gtccatgcac
     5881 aagatcatct gatgacgacg atgacattat tggaagttgc acaggaaatg aattatttgt
     5941 atcaaaaaaa taaatagaaa ggaaggatca ttgtgcagga tacagtaaaa aggaaaatcg
     6001 aattagaaaa aaagcaactt agtttgaaaa acatgtattt caatcgttat ctaatcgtac
     6061 gttacctgac tgcctttttc tttttcatga acatgcaatg gatgattctg cttctatcag
     6121 ctaaaagttt aggaagtagt ttaccgatga ttctgatttt agctattttg cctgcagtag
     6181 gagaacaagt aaagctttat cgaaaacacc aaacgaacgt tccatggaca aagtggtatt
     6241 ttttgttcca gagtgtcttt aatttattag tgattccagt gttgtttacc tcaggattta
     6301 cattcttgta tccttttatg gcaaataaca atggaggaca gttatttgtt ttcattcttg
     6361 ttgtaagcgg tatttttgcc agtgcattta tacagtatcg tttaaagaaa atttcactca
     6421 accaagacca acagtatatc cgtattaaac aatatgaaaa agcgttatat ttaggaaagg
     6481 agaataacta atgtttgatt ttttgcagaa atacctgatg ggacctatgg ggaaaattgc
     6541 gcaacttaaa atcgttcggg ctgtcatggc agcggggatg gcttctattc ctttcacgat
     6601 tgtaggctcg atgtttttgg ttttaaatat tttgccatta ccgttcccat ttttagaagg
     6661 attttttaat gcaacttttt tcaaagttag tgacttgtac atgatcgtca atacaatgac
     6721 gatggggatt ttatctattt actttgccat tgtgtttgct tatgaattaa cgtcaattga
     6781 acgagatgaa caaaaattaa atgttaatcc gctcacgggg gcattactat ctgtttttgc
     6841 attctttatg tgtatccctg aattgatcat gactgatggt aaaatcagct tgattgcttc
     6901 tatcaatgag acagaaactg tagtaaatgg tattaggatg ggctcttttg tcgaacgttt
     6961 aggaacttca ggaatcttta cagctattat tatgtcgatt attgcggtcg aattgtattg
     7021 tatgtgtgtc aagagaaatt gggtcataaa aatgccagat gttgttccgc caggagtttc
     7081 tcgttctttc actgctctga tcccaacatt tgtcattgcg tttgtggtga tgatcatcaa
     7141 tggattatta gttgcactag gaacggatat cttcaaaatg attgctatcc catttgggtt
     7201 tgttacgcag ttgacgaata catggcttgg tgtcatggtg atttatttct tgatccatgc
     7261 attgtggatc gtagggatcc atggagcgaa tatcatcact tctttcttga ccccgatcgt
     7321 attagctaat atggcagcta acgcacaagg cgcaaattat ccgttggcag gagaattcaa
     7381 caattcttat gtaaccgttg gtggatcagg tgcgacttta ggattgatca tctttattgc
     7441 attcctcgcg aaatctgatc agctgaaagt gttaggaaaa gcctcacttg taccaggatt
     7501 attcaatatc aatgaaccaa tcattttcgg gatgccaatc gtctacaatc cctatttagc
     7561 ggttccgttt ttcttagctc cgatggcttc tgctacactc gcttattttg ccattcggct
     7621 ggaaatcgtc aaaccgatgc ttgcacagat gccgtggcct tcaccagtcg ggatcggagc
     7681 atttgttggt agtggtggtg attggaaagc tgctgtgtta gcagtcattt gtgcaatcat
     7741 cgcattcatt atctggttcc catttatcaa attctatgat aataaattat taaatgaaga
     7801 aagagaaaag gcagcagaat tagctagtga aaagttaaaa tgatttctaa gaaaaaagga
     7861 actgtgacaa aaaatcacag tccctttttt tcttagaaat gggaaaccac tagtatataa
     7921 ataccattat tcttcaatca accgcttcac gattgcataa tccccttcat aaggttcatc
     7981 tacaccattg attttttgat agggatccac gccttttccc gcaataacga ctgaatcttg
     8041 cggagcgctt tctgctaaag cgcgtcgaat cgcttcagga cgatccattt cataatgaac
     8101 gatcaaatct ggattagtaa ttgcttcatt gatttcttcc gcgatttttt tcggatcttc
     8161 aaatgctggg tcatctgccg tcaaaaaggc gatgtcagct gtttctgata gcacttttcc
     8221 aaaatcatgt cgacgggaga ttgctttgtt tcctgggctg cctaatacaa caattacacg
     8281 gccatctgga tgttcatttt tggcaaattc cagcaatgtt ttcaagctta gataattatg
     8341 tgcatagtcc acatagacat gcgctccatt ggattggatc aattgatcca ttcggcctgg
     8401 tacacgagct tcttttaatc cgtcttgtgc atcttgactg gaggcacctg ttagtgctgc
     8461 ggcaatgatc gcactggctg cattttcttg gttgaatcct ccagccagca aaatatcata
     8521 agcagtatcg cagatagcta agcgatcttc atgagaagat aaagtaaaac cgtgagtacc
     8581 tttatctgaa cggatcactt gataattgct ttcttccgaa cgaccataag tgatcgttgg
     8641 aatctggaat agatcggctg tttccctaag taaatcaaaa tagtcacttt catgatttaa
     8701 aacaactgtt tttgaattca agatcaattg tcgcttgcaa tagaaatagt catcaaatgt
     8761 cggatgttcg atcggactga tatggtcagg cgagatattc aagaagattc cgacatctaa
     8821 agtcaagccg tatacgcgtt gtgttttgta agcttgtgaa gaaacttcca tcactagatg
     8881 agtcatacca ttttcaactg cttctgacat catacgatat aaatctaatg actcaggcgt
     8941 tgtcaaatgg gatttgaaat atgttttgcc atctaacgtt gtattcatag tagaaagcaa
     9001 tgctgttttt ttatttgttg tgtgatccaa gattgctttt gtaaagtacg cagcagttgt
     9061 tttacctttt gttccagtga atccgatcac tttcaattta ttttgcggat agtcgtaaaa
     9121 agccatagca agaagcgcca ttgctttacg gatatccgtt acgatgattc ctactgctga
     9181 attttcgtat ggttgttctg atacataata ttgaataccc tgttcgattg ctgaatccaa
     9241 atattcttct ttgaaattca ttcctttaca gaaaaacaaa gtagaagcat cagcttttct
     9301 tgaatcataa cttaactgaa gaaattcagc tttttctggt acatcaagat gccagcctct
     9361 tgttgaaaca aattctttta atagattttc ttttaatagt aaatgacgga tgtcttctaa
     9421 agagaagctc attgattgat ccctcgcttt attcaatttc ttggtttatt atagcacact
     9481 ctttttaata tatcgtttgt ttccgctatg acaaaatcca gctttattca aattttcttg
     9541 acacagggga caagcggatg agtattttca taaacaatga actgactgta atagatagga
     9601 gaacgaatag tgtctccaac aatccaaaaa cataataatt caaaaagacg ataagactat
     9661 tggtaagtaa aagtccttgc ggcattggaa gccgaaaaaa tttgtggaaa ataatcggcg
     9721 gtatcgttat accgccattt gaggccccga ctgtgtacaa tgtgtaaacc ccaagactga
     9781 acaaaagact tcctgaaatc agtgaaaaga aatgtgagga gatcatttcc acttttggaa
     9841 caatctctaa aacaacagga aaaagcagac ttcccgctac agtcttaaaa aatactgatt
     9901 ttcctaatag gacagcggct agaagcagca tcataagatt gatgctccaa acagtaactg
     9961 agcgttggat agaaaaggcc gtttcaacta aatgtccgat ggcgcccact ccggcggaag
    10021 ctatatcgtg agggagcaag aaccaattca atccaactgt gataaagaaa agacctaaaa
    10081 atataacggg tagttttttt atttcttgtg tcattgatat ctcctataaa tgttagccat
    10141 aaaaggctgt atatttcttt actttaccaa aaaaacgaaa ccgaattcaa aaaaacaatt
    10201 gttcttataa aagttatata aaatcgattg ccagtttctg ttttaccaat taaaatgata
    10261 gtaatgtttt gtagaaagtt ggaatctgac cgatggataa tcaaagaaaa ccagcattag
    10321 atcaattaac accgcaagaa aaaatggcac gaggctctgc ttggatgacc gccagtaata
    10381 tcatttcaag attgctaggc gctgtctata tcattccctg gtatgcttgg atgggcgaaa
    10441 atgctaaggc tgccaatgga ttattcaata tgggatacaa tatatatgca ttgtttctac
    10501 tgatctctac agcaggaata cctgctgcga ttgcaaaaca aactgcacgc tataattcat
    10561 tgaatgaata tggcacttca cgacgattat ttatccgtgc attacagatg atgggcgggc
    10621 taggcctgtt gtttgctttg ttcatgtaca tcgcctctcc ttggctagct catgcttctg
    10681 gtggcggaga agaactgatt ccaacgatgc gttctttgag tatcgctgta ttggtttttc
    10741 cttgtatgag tgtgatacga gggtattttc aaggcaatca agaaatgatg ccttatgcgc
    10801 tgtcgcagat tgtagaacag gtggcacgta ttttttatat gctattggct acattcatca
    10861 tcatgaaagt catggatggt gactatgtga cggcggtcac gcaatcaact ttcgcggcat
    10921 ttatcggtat gctagcaagt attcttgtcc ttttgtattt tttgaagaaa catcaagcgt
    10981 atacatcggc gtttattcac tacagcgaaa acaaaataaa tattgcaacg aaggaattgt
    11041 tgttagatac cgttaaagaa gcgattccgt ttattattgt gggttcaggg gtaacgatct
    11101 tcaaattagt cgatcagttc acttttatga agatcatgtc tgcatccacc gagtattcca
    11161 atgcacagtt actggatctt ttttcgattt ttagtgccaa tccagataag ttgacgatgg
    11221 tagttattgc attggcaaca tcgatcgcgt ctactgggtt accgttgatt acagaagctg
    11281 ttacgttgaa agatcgagta ggtctggcaa aattgacaag cggaaattta cagttgtttt
    11341 cattttttat gtttccggcg acatttggtg ttatgttact tgcctatccg ctaaatacat
    11401 tattttatac accggattct ctaggaagta atgtactgat ccaagcaagt tttgtaggac
    11461 tcttcctagg actatatatg ctagtttcca acatgctgca aggaatgttt gaaaacaagg
    11521 cggcaattaa ttatttggtt attgggtttc tagtgaaact ccttcttcaa tacccagcca
    11581 ttcgtttatt tgaagtatac ggccctttat tggcgacaat gatcggattt gctgtgtctt
    11641 gtaccttgat cttaaagaga atccatgaag tagcccgctt taaaccaagt tttgtctggc
    11701 gcaggacatt gctgatcttt attcttacct tgattatgct tttggcttcg tggatcacaa
    11761 agatgatttt tggtgctttt ttaaacgaag atagcaaatt ccagtctcta ttgttgattc
    11821 ttgtagtagc aggtataggg gctttagtgt atggttattt agctttgaaa atccgcttgg
    11881 cagaaagact actaggacca ggaatagcgc gtttacgaca taaattaaaa ataaaataag
    11941 tgaatcagaa gagctagatt gatgctcttt tgaaatgggg gaaacgcatg cgtttagata
    12001 agtttttagc agatatggga cttggcagcc gcaaagaagt caaaggattg atcaaaaaag
    12061 gaacgatcga agtcaatgga caagtggtga aaagcgataa agcgcaagta aatgaattcg
    12121 aagatgcggt tacttattta ggagaaatca ttacgtatca aaaagatttt tactacattt
    12181 tgcataaacc tgcaggagtc atttctgcta ctcaggataa tcatgatcaa accgtaatcg
    12241 atttattgga agaccaggat tatcgggaag atctttttcc agtcggccga ttagataaag
    12301 acacagaggg cctcttgatt ttaacgaatg acggggtgtt tgcccatcag ttactatcac
    12361 ctaaaaaaca tgtggagaaa gaatatctag ctgaggttag cggtataatg acagaagaag
    12421 atatccgttt atttgcagaa ggactgatta ttgatggcga tgagcagaca ttgccggcaa
    12481 aactccaaat tgatcaagta gatcaagaga cagaaacttc aattatccgt ctgattttgc
    12541 atgaaggaaa gtttcaccaa gttaagcgaa tggtcaaagc agtaggaaaa gaagtcttat
    12601 atttaaaaag aatccgtatg ggaaaatttt ggctgcctaa agatttgaat aaagggcaat
    12661 atcgacccat gaccaaagaa gagctagaac aagtgagaga aaaataattg aatggatagc
    12721 taaaagaata agcagagtag ttgtagcgcc atctgaaaag cagacttgtc cgtctgactt
    12781 tcggatggct tttttgtgaa atttcggctt atttccgtag aagctacttc tggaacaccg
    12841 tttgttcgga ataagggact gtgacaagac ttttgttaca gtccccattg ttccttgtga
    12901 ctcagagtta gatagtaagg acacgatctc cctaatactc aggccaaaac gctgaattca
    12961 caacctctga taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa
    13021 aatatgagga actattttcc cgtttttttc tctaatactc aggccaaaac gctgatttca
    13081 caacctctcc tatactttgt ttcattttcc ctatactttg tttatttatt ctcattattg
    13141 aaagcgctat aattacgttg cgaatgaatc gaaaggggtt tttagatgaa aaaacgaaag
    13201 gggttcaatc atttttttat gaatctatgg cgttataaag cacttgtcct gatggctgta
    13261 ccgggtatgc tttggatgat ttttttcttt tacatacctg taatggcgaa tgtcgtagca
    13321 ttcaaaaatt ttcatatttc agcagatggg ttcttggcta gcttgaggga aagtccttgg
    13381 gtgggttggg aaaatttcaa atttttattt tcttcggatc aagcatttct catcactaaa
    13441 aatacaattt tatataatgt agcatttatc cttttgaatc tgctgatctc agtcgtattt
    13501 gcaatcatta tgagcgagtt gagaaataaa cgactcgtta aagtttatca aacgatgtcc
    13561 ttactacctt attttctatc ttgggtcatt atcagttact ttgtttacgc ttttttaagt
    13621 cctgacaaag gaatattcaa tcagtggatc actggacatg gaggagaagc tgtcaattgg
    13681 tataatgaac cgaaatattg gccgtttatc ttggtgttca ttggtacatg gaaagggatt
    13741 ggttataaca gcattattta ctttgcatct gttatgggaa tcgatccgac ttattatgaa
    13801 gctgctatgg ttgatggagc tagcaaatgg cagcagatca aacatgtgac gataccacaa
    13861 cttattccac taatgacgat tttaacgatt ttagccgtag gaaacatttt ccgagctgat
    13921 tttggcctgt tttataacat tcctaggaat tccggtgcat tatatgatgt gactcaagtt
    13981 ttggatacgt atatctacaa tggcctgaca tccacaggag attttggtat gacggctgct
    14041 gcaggacttt accaatcagt tgtcggcttt gtcttgttga tgatcacaaa tacgatcgcc
    14101 cgacgttttg atagcgattc tgcattattc taaggaggaa aaaaatgaaa aaaaagaaag
    14161 tggagagagt ccaagtccgc tctttcaata agacggctaa ttttttctct aatataatga
    14221 ttgcactctt tgctatttcc tgtattttgc catttatatt tgttatcgcc atctctttta
    14281 ccgatgagtc catattgtcg actcacgggt acagtttttg gccagaaaag ttcagtatat
    14341 ttggttatac gtacttgttc gaccagatgc aggataaaat tttccaagcg cttttcgtca
    14401 ctgtacttgt tactgtttta ggtacactga tcaatagcac ggctacttct ttatatgctt
    14461 atgcgatttc acggtcaaac tttccattcc gtcgtttttt taccgttttt tgtttgatta
    14521 cgatgttgtt ctcaccaggg atggtggcca attatcttgt tatgacaaat cttcttcagt
    14581 taaaagatac gatttgggca ttgatcttgc caatggctgt cagtcccttc aatattattg
    14641 tgatgcgcac attctttaaa cgttcggtct ctgattcgat tattgaatcg gcacggatcg
    14701 atggagctag cgaactgcga atatttgttc agatcgtttt accgttagct gttccaggta
    14761 ttgcgacaat cagtttattt gccgcattgg gttactggaa tgactggttc aatgctttac
    14821 tctacatcca agatgataag ctagttccac tacagtatct tttgatgaaa atccaaagta
    14881 atattcaata tctgacacaa aattcaggag caggaagcca attgacaggc ggattagcct
    14941 cagttccagg agaatctgcc agaatggcga tcgtagtcat ctcgacgttg cctattgcga
    15001 tcagctatcc atttttccag aagcattttg tcaaaggtct aacaatcggc ggagtaaaag
    15061 aataaagaaa caaaaatata aatcataaaa ttaggaggaa gaaaaatgaa gttatggaag
    15121 aaactagcct ttacaggtgt ttcagcgttg ttgttgggaa cattagcagc atgcggaggt
    15181 tctggttcta aagaccaggc agaagctagc aattcggaca ctttgcagat gtatcaaatc
    15241 ggagataaac cagataattt cgatcaattg atggaagtag caaacaaacg aatcgaaaaa
    15301 gagatcggtg taaaagtcaa tatcaattac attggctggg gcgattacga aaagaaaatg
    15361 aacgtcatca tttcttccgg ggaaaattat gatatcgcct ttgcgaacaa ctatgtttcc
    15421 aatgcccaaa aaggagcctt tgctgatttg actgaattag cgcctaagta cgctgaaaaa
    15481 gcttataatg atttagatga agcatatatt aaaggaaatc tggtcaatgg aaaattatat
    15541 gctttcccag tcaatggaaa tgtctttgct caacaagtac ttacttttaa caaagcttta
    15601 ctagataaat acgatctttc aattgatgga atccaatctt acgctgatgc agaaaaagtc
    15661 ttgaaggaat tccatgaaaa agaaccaaac acggcagctt ttgccattgg acaaggcttc
    15721 aaagtccaag ggaactttga ttatccttta gggaatacgt taccatttgc tattgatctg
    15781 gatggagatg attcgaaaat catcaaccaa tacgataatg aaacgtatat cggactgtta
    15841 cgtacaatgc atagctggta caaacaagga ctcattccaa gtgacgctgc aacgagcaat
    15901 aaggattatc cactagaagg aaatacttgg ctaatgcgtg gagaaacaca aggaccgtat
    15961 gattatggcg atacaatttt gacaaatgca gcaaaacaag aacttgtctc aaaagcaatt
    16021 actgttccac taaaatctac agctcaagca caaatggcaa attttgtcgt atcaaatact
    16081 tcaaaaaata aagaaaaatc agtagaactt ctagggctgc ttaacagtga tccagaatta
    16141 ttgaatgggc ttgtttgggg gatcgaggga gaagcatggg aaaaagtcga tggttcagat
    16201 gataaaatca aattgctaga tggttatcag ccaaatacac atatgtctgc ttggaataca
    16261 ggaaacaaca agattctata tacacaagag tctattacgg atgacatgat tgccaaacgt
    16321 gatcaatcga ttgctgatgc agaaacttca ccgattttag gattcagctt caacactgac
    16381 agtgtcaaaa cagaattaag taatatttct aatgtcatga atcaatattt agatggattg
    16441 aatacaggga ctgttgatcc agatgaaaca ttaccgaaat tgaaagacgc tttggacaag
    16501 gctggctatg ataaggtatt gaaagaaatg caaaaacaat atgatgagtt ccgacaagaa
    16561 taataatgaa taaagacaaa ggggttgtga caaaagacgt gtcacaacct cttgttccga
    16621 ataaacggtg ttcaaaagcc agtttctcgg tattaagcta aatatatgta aaaatgtgga
    16681 aagccatatt cacaaaattt ttcttactac tcgaaactaa gcggctattt cacaaactct
    16741 tggtaaacgg tgttcaatca gctgaccctc ggtattcgct cacaaaacga caaaatatga
    16801 ggaactattt ttccgtttgt ttctctaata atcaggtcaa ggtgctgatt gcccaacctt
    16861 tttttgtata atgagaaagt ataaacttaa tgtttggagg agaagatatg ttagggaagg
    16921 ttttggaaga gttatttatc cggatctggg tcattataaa actaaccttg tatttctgga
    16981 tatatacatt tgccggcggg atcatctttg gattaggtgc ggcatggaaa acagtcaatg
    17041 aactatttta tttgtacgga ttcgagtata aagaaatcac aataaaaaga ggctggaata
    17101 tatataaaag aaatttttta agaggcaatc tgctatttag tttattttta tctggtactg
    17161 ctttattgag ttacaattta tatttatctg ttcaaatcaa agggctcatt tttttagcta
    17221 ttgattttat tttacttttt gccttgctct gcctatttgc tacttatcaa tacagtatga
    17281 ttttagatag tgaatatacg atctctgttc ctaatctgct aaagctaagt tttatttcgg
    17341 ttttttccag cttttcgtct tttctaaaaa taattattgg tagcggtata attttaggcg
    17401 tgacttggca attcaaagga ttgatcctgt ttggtgtcat tggtcttttg acggtttgga
    17461 atggtacgat gacaacacat tggcgtgaag aattagataa acagttggaa agttatgaat
    17521 aagtttcgga ttctattttc aaaaggaacc ttactaaatc gtctgttgcg gaaatacgcg
    17581 gttatcatga tcggtgtaac gatgactgct accgttattt ttagtatcca tacttgggaa
    17641 caaaatcaaa aacaggcaga aaacatgaca agtgatgccg ttcaaagcac aagcagaatg
    17701 ctgaatgata aaacaacctt gagtaggatc atcaaaaacc agcttgtagg gaattccgaa
    17761 aagatcgaaa atgtgacgac ctacttaaca aaacccatag atcagtatct gatgtatgta
    17821 tacgaacagc aaaacagtac cgatgaatta gtttctttcc caaatcaaat caaagatctc
    17881 tacgcaaatt atgaagaact aagtgcgata tatatcgtgt tgaatcaact accggagtat
    17941 tatgaatctt ctagagaaaa caaaggtggg gaaataaaaa aggggacacc aaaattacta
    18001 gacgcctttt atatcaagtt gcctatcaca caaggaggag ctgagtcagg aagtattttt
    18061 attggttttc aaaagaaaga actagatatg attttagaaa atctaacgtc attcaatgga
    18121 ctctctttat acatgatttc tggaacgaca aatcgactat acacattcca tgataataaa
    18181 atagctaaag aaacgtttga aagacaagaa atgatcatca cagagagtct gaagaaaaat
    18241 tcacaattgc cgattgacga tctggaaaaa aacaattttg ttcaacacca agaactgtct
    18301 gatgattatc gtatattagc tgtactagat aaaaaaagtg taaaaatcga aacgggaaaa
    18361 aatcttgccc cgctgatcat tggtatcatt attttagaca atatactgct tatctttctt
    18421 tataaaacat tcaaacgata ttcacagcaa gtatctatcg tcatgcaggc catggatcaa
    18481 acagcagcag ggaatttaga gacgcggatc gacataacaa acacggaata tgaactgaag
    18541 gaactttcaa tcggtatcaa cgaaatgttg gatagcatca atcagtttgt agaagacatc
    18601 tacaaattag aaatcaaaca gcaagacgca catatgcggg cgcttcaagc acagatcaat
    18661 ccacactttt tatataatac attagaatat atccgaatgt atgcaatcag cgaaggaagt
    18721 gaagaattag cagatgttgt gtatgcgttt tccgctttgc ttcgaaacaa tacgaatcaa
    18781 gagaaaacga tcactttaaa agaagaactg gacttttgcg aaaaatatgt ctatttgtat
    18841 caaatgcgtt atcctaatcg agtagcctat cattttatga tcgatcctga tttggaaaag
    18901 atcgaagtac ctaaatttgt gatccagcca ttagttgaaa attattttaa acacggtatt
    18961 gattttactc gattcgataa tgcgctaagt gtcaaagtct tgcaggaagg caaacgggta
    19021 aggatcatca tcaaagataa tggaaaaggg atgactgaaa aacggctaaa acagattgaa
    19081 gaaaaactgt ctcatcctaa agtggaactt cacggttcta tcggtctgca aaacgtgaat
    19141 gaacgtttac gtgccagctt cggcagcagt tattatatgt cgcttgagaa taatgagaca
    19201 ggtggactga ccgtttctat tacattcaag gagggatgag cgtgtatcaa gtgttattgg
    19261 tagatgatga atacatgatt ttgaatgggt taaaaaagat aattgattgg caaagtttag
    19321 gctttcaaat agtagcaaca gcagagaatg ccaaagaagg actagctgta cttgaacagc
    19381 gacagattga tttagtagta acggatgtga caatgccaga aataaatgga ctggaattta
    19441 ttgaagcggc tcaaaaagaa cgtcataatt ttgaatttat gattttatca ggataccaag
    19501 aattcgatta tttgaaagga ggtatgcaat taggcgccgt gaattatttg atgaaacccg
    19561 tgaataagtt cgaattggtt gaaagcctca agaaaatcaa aacacggtta gatcagcaaa
    19621 atgaacaaaa aaatcaacaa gaaatctatc aagaactgtt attcagtcaa tggttgaatg
    19681 aagaattgga tgaaataagt gaagaagaaa taataggaca aataagtgag aagcagcata
    19741 ggatagtatt gattcaactg gcaagaactc atgatactct tatcaataga tggttgcaag
    19801 aacggcaaca aatcttttac tatcaacgaa attacggaga ccgtgtattg atcacgttgt
    19861 tgttggaggc agatgaagtt gatggcttct gttgttttgt tcaagaaaac tttcctgatc
    19921 aggaatggct gatcagtatc ggggaagaga cagattcttt ggacaaaatc cctgaaacat
    19981 tccaacaagc gaaagacaat ctacagttgc atcaatttta tggagataaa gacgagcatg
    20041 ttttttacgc agtacaagca gaaacaaaag atcaaaccat cgatttttca agtttcagac
    20101 gcgtgctgca aaataaacaa ttggaagtcg ctcaaaaaat gatcactgat ttttttgaac
    20161 agtttcagtt agcagccatg atgccggaag atatacgata ttccagtttt ttactgttta
    20221 tggagattca acgggaattg attgatctgg aagatgagga atatttacaa ggaatcgaaa
    20281 aaatccatca ggcaaaaacg gtgcaagaac ttcagcagct acttctgtca ttcatcaaaa
    20341 agcatcagag acagaaaaag tacagtgaca atgtggaaaa agtaatcgta atcctgcacc
    20401 agcattatca agaaccactt acactcaaag aagtgtcaga aaacctgcat ttaaatgtca
    20461 tgtatctagg acagctgttc aaaaaagaaa cgaaaaaaag tttttcagct tatttgaacc
    20521 atttacgtat ggaaaaagcg aaacaactgc ttttgcacag taatcaaaac atcaatgaga
    20581 tagcaagtga gattggctac aacaacacca cgtatttctc taaattattc aagaaaatcg
    20641 tcggcagatc ccctaaagag taccgagaaa acagtggaga atcataaaaa aaaaagccaa
    20701 tgtaatgaaa taacttataa aaaattgtct agaaatctaa ttttgggctg ttcttattac
    20761 ttgaggcaag gcagcttttt catgacctct cgataaacgg agttcaaaag ccagtttctc
    20821 ggtattaagc caaatttatg caaaaatgtg gaaagccatt ttcacaaaat ttttcttaat
    20881 actcgaaact aaacagcttt ttcacgacct ctccactaaa tggtgttcaa tcagctgacc
    20941 ctcggtatta gctcaaaaaa tggcaaaata tgaggaacta ttttgccatt tgtctctcta
    21001 atactcaggt cagaacgctg atttcacaac ctctcaataa acggtgttca aaagcttgca
    21061 tctgcggtaa taagaccaac caaacgaaaa atatgaggat ctatttttgc ttggctgttc
    21121 ttattacttg atgcaggaca gctttttcac aacctcttgt taattatagt ttgataagga
    21181 aaaaggcaaa tcttttgctt gatatttctt agggtgaggg atgatcccta attggtaaga
    21241 gatcgtgccg cctttcagca aatcttgatg ggtaaaatat aatttcgtat attctctgtc
    21301 catccgtttg attttatgga taaattgttg ctgcggccga ttaggcgttg cttcaatcgt
    21361 caattccttt ccatttgaca aaagcaaaac agccttgtca attaatggca taccgataac
    21421 atattcaccg gttccaggcg tgacaggata aaatcccaga ctattgaaga tataccaagc
    21481 ggccatactt ccattgtcct catctccagg gtaacccatt ggagaatcgt cgaaggtctg
    21541 agtcatcaac tgtttaagca gtggctgtgc catttcaggt tgtcctatat aactgaacaa
    21601 gtaaggatag tgaaaacttg gctggtttga aatagctaat tgtccaaatt ctatcgcggc
    21661 catctcactc atttcgtgga tctcaaaacc atatcctcct gggtcaaacg ttgggggctg
    21721 attgcacagc tcaatgagtt tttctttata tctctcactg ccaccatatt ttccgatcag
    21781 tcctgaaaaa tcgtgataaa cagcaaagct gctttgccaa gcacttcctt ctgcataatc
    21841 ttgtccccaa cgattagctg aaaatggttc tctgaacttg ccatctttat cttttgaacg
    21901 cataaatcct gactcatagt caaagatatt ttgatagttc aatgattgct gctgatattt
    21961 cttcgtcatt tcctcttctt ctagtacctt ggcaacttgg ctaatacaaa aatcgctata
    22021 agcatagtct aatgtgtgat tgactgattc gtggtagtga ttaggaacat agccatatgt
    22081 caagtaatct tctgttcctt ggcgtccata atttggatgt ttgctttgaa ccgtagcacc
    22141 tttttccatt gccgttagaa attcaggcat caagtctcgt cggatatctt ttacagcagc
    22201 atctgcaatg accgcatcga tcaatgtccc aggcataagt ccacgttcat caggagacag
    22261 ccattttggc aaatagccac tttctctata gctgttcaaa aaaccttcca gcatttcttc
    22321 gtatttttct acagcaatca aagaataaag aggataaacc gttttatacg tatcccaaaa
    22381 cccattattt gtatagagaa caccaggttt tatagatcga ctagtcgtat catagtggat
    22441 tttttgccca ctaggatcaa tttcataaaa tgtttgtgga aataaaaaca cccgatataa
    22501 attatgataa aacgtccgca attgttgttg atcatggtgt gtgagctgta tacgatcaaa
    22561 ataggactgc cattgttctt gactgtgagc aaggtaagtc tctttgcttt ggttttgttc
    22621 tagttccagg ttataagctg cttgttccga gctgataaaa gatgtcccaa atcggatagt
    22681 ttgttttttt gtctgttcaa aatacaacgg gatcgagtcg ctatttttgt tggaaacagc
    22741 taactcatca attgttaaag gatattcaaa tctcaatata aaataaaaag aaaaatcagg
    22801 atcttctgaa ccagcaaaat gtgtgatttt tccttccact gtgtaaggat ctataacaaa
    22861 gagctgatgg cgtcccggaa aggataaaag taaaccgctg tcatttttgc tgtaatcaat
    22921 agataagatt ccgccataca tgctaggtat caatgtagaa cagatgccat aacgtaattg
    22981 acagatcgac agatgagtcg ggcaaaatat actttcttct gggcggtaag aactttgagc
    23041 atggaaaagg gtgttctcct gtagttttcc attgatcggc gtaaacagca tatgactgaa
    23101 atcacccatc caaggacttg gttgatgggt aagacggtag ccttgaaaaa cgcggtcatc
    23161 aggatgaaac caccagctgc cgttttgatc cgtagtttgc ggtgcaaaat aattcatccc
    23221 aaaaggaacg ccagtataag gctggcagtt cccattagag aaatttggct gattcgctgt
    23281 tgcatgtcta gtatctattt gaccgatatt cattttattt ctcctttgtt gattgtcttt
    23341 tgatgaatga aactggaaat ttactatcgg atggtcgatc ttttgtctct aaccaagtga
    23401 ccaaagcatc tcccgcaagc ttacctaact gttcaaaatc ttgtgcgatg gttgtcagtg
    23461 gcgggtcaac aagagctgct gcttggatat catcaaatcc gataattgaa aaatcttcag
    23521 ggatatgata accatgctgt ctcaagagat tcatggtctg gatagcgaca acatcgtttt
    23581 cacaaacaaa agcagttact tcatacttag tgatataaga aagcaattca tctaatgtcg
    23641 cgcttttgtc atccagtgaa gtgtggaaag tcaaaccagc tttgtccaat gcttcaaggt
    23701 aaccaaggta acgctgtcga acggattgtg gatgagtctg cgtaccaaac aaataagcga
    23761 tttttgaatg tccctgttcg atcaaataag aggcagcaag cgcaccgcct tggaaattat
    23821 cggaaagaac ggtaggaaaa ggtaactcat agattttttt atctaatatg acgacaggga
    23881 attctttcaa tgaaagctca aaaagtaagt caagatgttg ttctgtatca agagcataat
    23941 aaatcaatcc gtcaaattca ttgattagct cttttgctgt tttattttgt agaaagtcaa
    24001 gcgtcgtcat catgacatca atctgtttat cttgcatcac agggttcaat cccttgctaa
    24061 aatcaccaac agacaaatca gcgacatatg gaagaagaaa cagaatccgt cgtgtttttg
    24121 taggagaagc aagaatctgt tccggagaag cggatttaac gaaactgcct ttcccgcgaa
    24181 cgcgataaat aagtcctaat tgctctaatt cagtcaatgc acgtttggaa gtgattctgc
    24241 ttactttata ggtacgtgaa agttcttttt cagttggtag ttggctgtct acaggtaatt
    24301 caccagttaa aatagccgtt tgcaaatcat taaatattgt ctggtacaat ggttgagtca
    24361 tataaacacc tcttaatgat atatcatatt caaataatac cataatggat gaaaaagtaa
    24421 ataaaaagat attttttgaa agcgtagaca taattggctg tatgaagtat aatctttaaa
    24481 gatatatcaa atagaaagaa ggttttatta gtggtttata aagatatacc aaaatcggtg
    24541 cagaaattta tggaagatat cacacaaaaa tgtggggata tccatgcgga ctgggcaaag
    24601 aattttacag cagcatttgc caatactctg ttgacaacag tcaaaaagca aaatgacgga
    24661 accacctttt tattgacggg agacattcca gcgatgtggt taagagactc tactgcacaa
    24721 gttcgtcctt atttagtgat tgcaaaagaa gatgaggaat tagctgacat gatcagcggg
    24781 ttagtcaaaa agcaattttt ttatatcaat atcgatccat atgcgaatgc cttcaacgaa
    24841 gaagctaacg gtgctggcca ccaaacagat catacaaaaa tgaacgattg gatctgggaa
    24901 agaaaatatg aaattgattc tttatgctac ccaatacagt tggcctatct tctttacaaa
    24961 aatacaggaa aaactgatca attcaatcaa tcttttattg aaggtatcaa aaaaatcttg
    25021 gacgtgttca aaacagagca agatcatgaa cactctcctt atacatttgt acgagacacg
    25081 acaagaaaag aagatacgct gatcaatgac gggcgaggtg caaaaacagc ttttacagga
    25141 atgacatggt ctggtttccg tcctagcgat gatgcttgcc gttatggata tctggtacca
    25201 tccaatatgt ttgcggtggt cgtgttaggt tatgtggaag aaatttttca aacgatactc
    25261 gatgataaag aaattgtaca gcaaacacag aaattgaaga aagagatcca agaggggatt
    25321 cagaatcacg gacgaacggt taatcaaaaa gggcaaacga tttatgcata tgaagtagat
    25381 ggaatgggaa acgccacagt catggatgac agtaatgtgc ccaatctgat cgccgcacct
    25441 tacttgggat attgttctga acaagaggaa gattatctgc aaacaagaag aacattgttg
    25501 agtaaagaaa atccatattt ctatgaagga aagtacgcaa aaggaattgg atcctcccat
    25561 acgccagaaa aatacgtttg gccgattgca ttagctatgg aaggaatgac aacgtcagac
    25621 aaatctgaaa aagagcggat attgaattta cttgtagcaa ctgacgcagg aacacacctt
    25681 atgcacgaag gattcgatgt gaacaatcct gaaaattata cgagagaatg gttttcttgg
    25741 gcaaatatga tgttttgcga attagtcatg gattactttg atattagagt agaaaagtag
    25801 gaggtatcgt aaatgaaaaa gaaagtatat atcatttctc atagccactg ggatcgtgaa
    25861 tggtacatgg cttacgaaca gcatcacatg cgactgattg aattgataga cgatctacta
    25921 gagctatttg aagttgatcc gtccttcaac agttttcatt tggatgggca aacgattatt
    25981 ttagatgact atcttcaagt aaggccagaa aaaagacagg caatccaaca agcaatcaat
    26041 gaaggaaaat tgagaattgg accattttat atcttgcaag atgattttct tatcagctcg
    26101 gaatcgaacg tgagaaatat gctgattggc atggaagaaa gccgtaaatg gggaacccct
    26161 gtcatgttag gctattttcc cgatacattt ggaaatatgg gacagacgcc tcaattaatg
    26221 aaacaagctg gtatttcagc agcagcgttt ggccgtggtg taaaaccaat tggctttgat
    26281 aatcaagttt tggaagcaga aaactattct tcccaatact cagagatgtg gtggaaaggc
    26341 cctgatcaaa cagcaatctt tggtctgcta tttgccaatt ggtatagcaa cgggaatgag
    26401 attccagtag aaaaagaagc agctcttgcc ttttggaagc aaaaattagc ggatgcagaa
    26461 caatatgcct ctacgaacca cttattgatg atgaatggtg ttgatcatca accggtacaa
    26521 aaagatatat caaaagcaat ccatctcgca aatgaactgt ttccagatta cgagtttatt
    26581 cattctaatt ttactgacta tctggaagca gttcaaaaag atgtgccaga agacttaggc
    26641 tcagtagaag gagaattgac aagtcaagaa acggatggct ggtatacttt agccaataca
    26701 gcatctgctc gggtttactt aaaacaatgg aataccaagg tccagcgaca gctagaaaat
    26761 attacagaac cacttgcgac gatggcttat gaagttagtg gaaactatcc ccatgatcaa
    26821 ttagattatg cttggaagac attaatgcaa aatcatcctc acgacagtat ttgcggttgt
    26881 tcagtcgatt ctgtccatcg ggaaatgata cctcgttttg aaaaagcaga tgaagttgga
    26941 aagtatcttg cacaagattc cttagaacag ctgaccgcag caatcgatac gaccggattc
    27001 ccaaaagaca gctttccatt tgtcattgta aatactgcag gaatggataa aactggtgaa
    27061 gcagaaataa ccatcgaatt agaaagaaaa agattcgctg aaggaatacc tgaacaacta
    27121 tatcaagagt tagaaaattt gcctaaacgt aagtatcatg tagaaacaaa aagtggggcc
    27181 actataccag ctattttatc tgaagaaact gtccaatttg gttatgattt gccgaaagac
    27241 cgtttccgtg tgccatatat ggcaagaatg atcaaagtga ctttaccatt agaaaacatg
    27301 ccagcatttt cttgggaaac attcgcgctt gtagaagggg aagcgaaagc agaagaaaag
    27361 gaaacaatga ttcatcagag tggacgaatc atcgaaaacg gccctctaca tttgacgatt
    27421 gaaaaaaatg gtaccattac aatggaagat cgcaaaaaca aacgaaagtt gaataatctg
    27481 catatttttg aagatatcgg cgatatagga aatgagtata tctttaaaca acctttctgt
    27541 gatcagccaa tcctatccag taacaaagaa aactctgaag taaaagtatt agtagataca
    27601 ccggaaatag caaaaataag tattctacag gaaatggaaa tccctgtttc tgcagacgag
    27661 cgtttagaaa aagaacagca gatggttgtg gaatttcgtt atcgaaaagc agaacgatcc
    27721 aaagaaaaac gaatccttca aataaaaaca atcatgacaa tcagaaaaga tagtaaaaaa
    27781 atcgactttg aaacgactct cgacaatcag atgaaagatc atcgcttacg tgtcttgttt
    27841 cctacaaagt tacatgtgga acatcacgaa gcagatagta tttttgaagt ggtgaagcgc
    27901 ccaaaccatg tgtctaaaag ttgggaaaac cccacgaatc cgcaacatca gcaagcattt
    27961 gtcaatattc atgatgaaga gtacggtgta acagtcggaa actttggttt gaatgaatat
    28021 gaagtaacag aagacggaca aatcgcagtg acgctacttc gcagtgtggg agaactaggc
    28081 gattggggat attttccaac accagaagca cagtgtctag gtgagcatcg gttcaattac
    28141 agcattgaac tacatggacc agaagaaaaa ttctctactt atttgcatgc atacgcagca
    28201 cagattcctt tttccactca acaaatcaaa catcatgaag gaacattgat ttcaaaacaa
    28261 caatatttaa cgataaaaag tgaaacgttt gcaattacag ctttgaaacg cagcaagttt
    28321 agtgataaag tagtagtaag aggtttcaat atgtctagtc atttagaaaa attggaaata
    28381 actaaagaca atggaaaaac tgtcatattg aatctgcttg aagaaccaac gaagcaagcg
    28441 gttgtcccaa taatccaacc ttatgagatt cggacaatcg gattcgagga ggaaaacgaa
    28501 tgtatggcgg aatagaagca ggcggaacaa aatttgtgtg tgcggtttca gatggtggag
    28561 aaattttaga aaaattaagt atccctacca caacaccaga agaaacattg gatcaggtat
    28621 ttgaattttt tgatcgttat gaattgaagg gaatcgggat tggctcattc ggcccgattg
    28681 gtatcgacaa aacaaaagat aattacggat acgttttggc aactcccaaa aaagggtggg
    28741 cacaattcga ttttcttggc acaatcaagg aacgctacaa tattcctgct gcttggacaa
    28801 cggatgtcaa tgctgctgca tatggggaat tgaagcaagg agcagcacaa ggaaaaaata
    28861 gttgtattta ccttaccgtg ggaacaggaa tcggtgcagg tgtcgtgatc aatgaagaaa
    28921 ttttttcagg gatcgcacat cctgaaatgg gacatatttg ggtgaaacgc catccagatg
    28981 accattatga aggtacttgt ccttatcata aagattgttt agaaggatta gcagcaggac
    29041 cgtctattga ggcacgcaca gggatcaaag ggcaagatct gccgcaagat catcctgttt
    29101 gggctattca ggcttattat attgctcaag cactgatcaa ctatacgttg acgttagcac
    29161 ctgaaaagat tattttaggc ggtggggtaa tgaatcagga tcatctcctt caaaaaatcc
    29221 gtcagcaatt tgttgaattg atgggtggtt atatggaaac acctcaagta agtgaatata
    29281 tcgttcgttg gggactgccg aatgaaagtg ggattatcgg tagtttgctg ttagcagaac
    29341 acgaacatca aaagtaagca gacaaattac acaaaaagaa cagagtctta tcattatctg
    29401 ctgataagac tctgttcttt tttatttcta ttcccataat ccaggtaaag ctttaccgac
    29461 tattttttct tgagtaaatg gatggatcat gtgcagttct aatgcatgga gcatcagtcg
    29521 ttcagctgtt ctattttggt agagagggtc tccaacgatc ggatgtccct tatgagctaa
    29581 atgaactctg atctggtgtg tacgtccggt ttccaaaaca caatagactt gtgtttgttc
    29641 agaaagtact ttgttgacag tgacatgtgt caaggcgctc tgaccatttt tatcatctac
    29701 gacccttttt ctccgatcat ggcgatctcg tccaatttta ttggtgatgg tcatatcttt
    29761 ggcaatttct ccccatacga tggcttgata tctccgatag atcatttttt gttccaacat
    29821 tcttccaagt atcggcaaga caaatggatt ttttgcaaat aaaacggcac cgcttgtttc
    29881 tttgtccaag cggtggacaa cgtaaggtcg ttgctgttta gtgtcgagat aagcagctaa
    29941 atgattgagt aaggtactgt tttctgtcgg ttcatttgga tgagtcttca ttcctgcagg
    30001 cttatccact ataatcaaat gctcatcttc atataaaaca cggatgtgct tcgcatctcc
    30061 taattgaact tcttgataat tataatctgt ttcttcgaat aacaatgtga tctggtcatt
    30121 gccctttact tcatgatgga acaaagcagg ttgttgattg atccaaacgt ttttacgtat
    30181 acgcaaaaag tgtcgaacct ttctaggaac taaccattcc ttttcaagca agtcgcgaat
    30241 tgttgtttca ggatggttca taggtaaagt gatcgtgatt ttcacaagtg tactcctttc
    30301 agtgcaattg cagactaatt gtaccatttt taaaacatat ttaagaaaaa acttacattt
    30361 ttctgttcat tcttatgtta ctctacttgc actaacgtaa aaaaacatat tgaactacaa
    30421 cttaagcagg aagaaaacac tctttcacta tggtaaaata agacgattga atcaaataga
    30481 caggagaaga agcaaatgga ttttcaaagc attttagaaa agataaaagc tgctttgatc
    30541 agtttttggc gttggatcag accatatctc ggacaattcc atcgatggcg aaagcgcatc
    30601 tggaaaaaat atcatgtgaa caaattgatt ttgctgattg gtttgatctg tgtcttagtg
    30661 acaagtatct acctctttat tttagcaaaa caagcaaatg tcgaaacgtt aaaatcagga
    30721 ttaagccaat cgacagtcat ttatgataag aaaaacgaag aagctggcac actgtacgcc
    30781 caaaaaggaa catatgtaga attaaacgcg atttctccct atatccaaga tgcagtaatc
    30841 tcgacagaag ataggaattt ttacgagcat cacgggtttg atatcaaagg gattgcccgt
    30901 gcagcagtcc gaatggtctt gtctggcgga acatcagggg gcggaggaag tacgatcact
    30961 cagcagcttg ccaaaaatgc gtatctgaca ttagaccaaa cgtttgatcg aaaagcgaag
    31021 gaattatttt tggcaatcga gatcgaaaag aagtacagca aagaagaaat cttgaccatg
    31081 tatcttaaca atgcctattt tggcaacggg gtatggggtg tccaagacgc ttccagaaag
    31141 tattttggag tagatgcaac gaatgttacg ctgtctgagg ctgctacttt ggcaggaatg
    31201 ctgaaaggtc ctggtattta taatccgatc gatcacccaa aaaatgcgaa tgatcggaaa
    31261 aacacagtac taagtgtaat ggaagaaaac ggaaaaatca caaaagaaca agaacaagca
    31321 gaaagccaga cagatatcag cgcgtatctt aatgacacat acgataattc agattctggt
    31381 tatcgttatc cttattattt tgatgcagtg atcgatgaag cagttaacga gtatggtctt
    31441 gatgaagaag atgtcatgaa taaaggctat aaaatctata cagctttaga tcaggattat
    31501 caaaagcaat tagaagctac ttatcaaaac agtgcattat tcccagcaaa tgcttcagat
    31561 ggtgccatgg tccaatctgc ttcagtagct ttagatccga atacaggtgg tgtacaagca
    31621 ctagtaggac gaagaggaga tcatgtcttt agaggattca gctttgctac acagatgcgt
    31681 cgttcaccag gatcaacgat caaaccatta agcgtatata caccagcact ggaagctgga
    31741 tacaagcctt ccagtatctt gaaagacgaa ccgcaaagtt attacgatgc gcataatttt
    31801 gacgggacat accaaggaga agtaccgatg tatcaagctg ttgcacaaag tttgaatttg
    31861 cctgctgtat ggcttttgca tgagatcggt ttacaaaaag gatatgataa agcagaagaa
    31921 ttcggcctgc ctttagcaaa atctgataag tattatggct tagcccttgg tggactggaa
    31981 aaaggagtat ctccattgat catggcgggt gcttacagtg catttgccaa tgatggtcag
    32041 atgtatacgc cgcatcttat cacgaaaatc gttgattcga ctggagcggt gatcgtcgat
    32101 aacacaaaca aaaaaccaaa acaggtcata tcaaaggaaa cagccgatga aatgaccagc
    32161 atgcttcttg gtacattttc aaatggaaca gcggctgctg cgaatcctgc aggttatacg
    32221 atagcaggga aaacaggaac cacagaaact aatttcgatg ccacaaaagc aaatgaccaa
    32281 tggatgatcg gttacacgcc agacgtagtg atttcgacat ggatgggtta cgaagaatcc
    32341 agcaagctgc actatttgga agggacaagt ggaaatgttg tcgggaaagt cttcaaatca
    32401 gcggcagaag gcatccttcc gtatacttca aaaacaggat ttagtgtagc agatgcctat
    32461 gccacaggag gacaagtggt agctgcagat caagttggaa acacaggaaa ttctaatgga
    32521 gagtctggaa attggcaaga taacttgaat caatatggtg aacaagcaaa agaagggctg
    32581 aaaaacttcg gcgatatggt gaaagaaggc gttcagggaa ttggtgaagc ggctaaagac
    32641 ctctggcgga aatatcaagg agagtagccc ctttgaaaac gaataacccc atgttacaat
    32701 agagagtaac tactaaaaga aaagagggca taacatgtca aacatctacg atagcgcgaa
    32761 tcaaatcgaa cgtgagatcc gtgaattacc agaattcaaa gcgttgaaag aagcgtacga
    32821 gaaagtacaa gcaaacgaag aagcacacaa actgttcaaa gacttccaag cgatgcaaat
    32881 cgaattacaa gaaaaacaaa tgagtggaca agagttcagc gacgaagatg caatgaaagc
    32941 acaagaaatg gctgtgaaaa tccaatcaga agaagtaatc aatgacttga tgcaaaaaga
    33001 gcaaggcttc agtacaatca tcaatgactt gaaccgtatc atcatgacac cagttcgcga
    33061 cctttacagc gaataaaact attttatgaa acaacagagg gtgtgaaaga gacgttcggc
    33121 cttgagcgat gacaaaattg cttcttattg ccgataggct gtctcttgaa caccatttac
    33181 caagaggtcg tgagcctacc gtttaactct gagttacaag gaacaatttc aaaaaacagc
    33241 ttctcatgtt tgatgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
    33301 attcagaaat aggagctacg acaaaagtct tgtcatagct cctatttttt gtcattcatt
    33361 tttcaagcgg tagaaatagc ctttttgagc taacagtttt tcgtaagtac ctatttcaac
    33421 gatttttcct tcatcgatca caacgatttt atctgcctct ttgatcgttg aaagccgatg
    33481 agccacaata aaagtagtgg gtgtttctgt caggtaattc agggcttgct ggattttttt
    33541 ctctgactgg ttatctaaag ctgaggttgc ttcatctagc aaaatgattt ttggctgacg
    33601 tatcaacgct cgtgcaatgg agatacattg cttttggcca ccagacagct tgttgccatg
    33661 ttcgcctact aaggtatcca gaccatcagg aagctggtca atcagtgaag aaagttgcgc
    33721 agcttcgatg acttcatcta aacgttcttt tgatacgttt ttcaagccat aagtgatgtt
    33781 ctctttgatc gaagcggaga acaacaaagt ggtttgagga acaacggcta aataatttcg
    33841 cacacttcgc atatccagtt catccaaagg ctgatcatct agaaaaattt ttcctgaagt
    33901 cggctggata aatccaatca ataagttaag gagtgtagat tttccagagc cagatggccc
    33961 aacaaaagca attgtttctc cagctttcac ctctagagaa aaatgatcga taatcggttt
    34021 gagtgagtcc ggataaagaa aagaaacatc ctcaaaacga aaatttccat ccaaatgttg
    34081 gatttttttc ttaccgtgat aagtttctac atcgccagca atcaacagtt cgccaataga
    34141 agtgatagat tccatgcctt ttgaaatcgt aggaatcagc gtgatcattc cagaaacgga
    34201 attgacgatc gtcgtgaaat acgtctgata catcacgaca tcgccgggtt ggatgcgccc
    34261 ttgtaaagct aatatcccag tgaaactcaa acaaatcagc tgaaatatct gaaaactagc
    34321 ccagctgact gatccgaaaa cagattgcag gatatctaag tggaatcctt tttcatagat
    34381 ttgagtaaaa tgcttattta agcgagttgt ttcgtgtttt tctaacccat gagctcgagc
    34441 aatcggtgct aattcgatca cttcgatcac ttttgcagaa gtctcttcca tttcttgcct
    34501 gaagtctgag ttggactgtc tgatcctttt acggaaaaag agagtaacga atgcggcgag
    34561 aggaacagtc aataagaaaa acatgaaaac aacaggactt ttataaagcg tgatacctaa
    34621 agctacgaat aaattgacag cgatatttaa tccgctgaca aatacttgag aggacaacgt
    34681 ttggatagct tctacatcac ggatgatctt tgactggatt cgtccagatt gcaattcttt
    34741 ttgataagga atagatagtt cttggatttt cttgataagg gtcgctctta gtccagcttc
    34801 tacttgacgg atcgaagtgc tatggtattt tacatgaaaa taattcgtca atatattttg
    34861 accaatcaga caagccatca aaaaagcgtt gaaataaatg gcctgcaact gagaagaatc
    34921 tttcgatgaa gctgcattga ttacattggc aatagcgatc ggcattaacc aagatggaag
    34981 atgtttgata ataaaaaaga gtcctgacat ggcaaaacgc caataatttc cctgataaag
    35041 atgcagcaat gtctgaaaag catttgcatg atatttttga taacttttct gtattcgttc
    35101 ctccataatc ttctccttaa caatcttggt aaataaactg caagtgttct attgcttcag
    35161 gaacataaat ctcaggagta gcttcaagag tggcgtacat tagaggacgc tcatatttga
    35221 tataatgcag taccgggcgg aaatctaaac agcccttgcc aacaggtacc atgcggatct
    35281 ttccattttc catgatatag tctttgagat gaagcgctgt aatataacca tgtaaattgt
    35341 ccaaggcacc tcggatcact ttttcctgat cagcatgatt ttctttatgc atcaaattcg
    35401 cacaatctaa aatgattttt aaatttggtg aagctacttc atcgattaaa cgtttagcta
    35461 actgatagtt atagattgga tgattgatcc ctgcttcaac agcaacagtt acgccaaaat
    35521 tttctgcatg agcgactaat tcaatgatag aatttctggc gatctgataa gcttcttcag
    35581 taaaattttc ttttgtgtaa ccgacagaga cactaccggt ttccgtagca atcatcttgg
    35641 cttgataggc agagcacaga gcaatttgct gtttgaaagt tgccaatgct tgtgcacgaa
    35701 cttcttgatt tttgctggat aggttgatat agcatcctaa aatggaaagt tcgatattgt
    35761 ttttttggaa gtattcacca aaataggcag cactcccaag tgtcatgtca gttaatttaa
    35821 gttgttcagg aaatgctttt tgtggtgcaa attggatatg ggacaagtga agctgtgata
    35881 ctttttgaac gatttcttca cgatttcgaa catctaaatc gtgggcacgg atgcctaaat
    35941 ttaatggaaa catctcaaac tcctttttgt aaataattag caagaggcag acgggattct
    36001 tttatcaatt caacaattat tcgggcaact ttatcagcgc cttctggact aaagtgggta
    36061 ttgtctttta gtccttctgg gtaattttta caagtatcag gcataagatg caggtagaat
    36121 ttttttgtct cttcttttga gaaggtctgg aacaattctt gtgatcttga gaacacatct
    36181 aaaagaggaa tatggtgttt ctcagcaaat gcacgcatcg cttttggata gtctccaagt
    36241 atatctggat tcaatgttcc gttttctaag taatctcgtc gcgtcacaga tgtcagtaag
    36301 accatttgga cgttcgcttt ttttgcgcat tcaaaaaata tctgcagatt ttttaaatag
    36361 ctaccgaagg gaagcgtacc tctttcttct tggattttct ggtcgttatg tccaaattgt
    36421 acaaataaga aatcattcgg ctgaaactgt gaagctagac gggctaacct tccttcctgg
    36481 ataaatgatt tggtgctgcg tccattcttt gcttggttat tgatctggat ctcgggtgaa
    36541 aaataagcag agattttttc tccccaacct gtctcgggac gcttgttttc atctttttct
    36601 gccgcagtag aatcaccggc aatatggata gtaggcatgt tatctcttct ttcataaagg
    36661 tttataggca atgaagcaga acagcaagag aagaagacgg agcaa
//
LOCUS       DAFELK010000026        34687 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFELK010000026
VERSION     DAFELK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.027"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            591..1280
                     /locus_tag="LP433_001516"
     CDS             591..1280
                     /locus_tag="LP433_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2005686.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="LP433_001517"
     CDS             1267..2475
                     /locus_tag="LP433_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2005687.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="LP433_001518"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="LP433_001518"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBL2005688.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="LP433_001519"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="LP433_001519"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBL2005689.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="LP433_001520"
     CDS             complement(6578..7273)
                     /locus_tag="LP433_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBL2005690.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="LP433_001521"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="LP433_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBL2005691.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="LP433_001522"
     CDS             complement(8472..8663)
                     /locus_tag="LP433_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBL2005692.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="LP433_001523"
     CDS             complement(8684..9574)
                     /locus_tag="LP433_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBL2005693.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="LP433_001524"
     CDS             complement(9561..10328)
                     /locus_tag="LP433_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2005694.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="LP433_001525"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="LP433_001525"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBL2005695.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="LP433_001526"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="LP433_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBL2005696.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="LP433_001527"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="LP433_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBL2005697.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="LP433_001528"
     CDS             14899..15282
                     /locus_tag="LP433_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005698.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="LP433_001529"
     CDS             complement(15450..16208)
                     /locus_tag="LP433_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBL2005699.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="LP433_001530"
     CDS             complement(16226..17044)
                     /locus_tag="LP433_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL2005700.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="LP433_001531"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="LP433_001531"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBL2005701.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="LP433_001532"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="LP433_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBL2005702.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="LP433_001533"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="LP433_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBL2005703.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="LP433_001534"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="LP433_001534"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBL2005704.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="LP433_001535"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="LP433_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBL2005705.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="LP433_001536"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="LP433_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBL2005706.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="LP433_001537"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="LP433_001537"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBL2005707.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="LP433_001538"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="LP433_001538"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBL2005708.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="LP433_001539"
     CDS             27086..27385
                     /locus_tag="LP433_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBL2005709.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="LP433_001540"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="LP433_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2005710.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /locus_tag="LP433_001541"
     CDS             27973..28209
                     /locus_tag="LP433_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBL2005711.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="LP433_001542"
     CDS             28352..30325
                     /locus_tag="LP433_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBL2005712.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="LP433_001543"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="LP433_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBL2005713.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="LP433_001544"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="LP433_001544"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBL2005714.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="LP433_001545"
     CDS             33204..34496
                     /locus_tag="LP433_001545"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBL2005715.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10569 a         6743 c         6858 g        10517 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt
    34681 ttccgaa
//
LOCUS       DAFELK010000027        32538 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFELK010000027
VERSION     DAFELK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.028"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..129)
                     /locus_tag="LP433_001546"
     CDS             complement(<1..129)
                     /locus_tag="LP433_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2005716.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDS"
     gene            402..2873
                     /locus_tag="LP433_001547"
     CDS             402..2873
                     /locus_tag="LP433_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2005717.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2976..4712)
                     /locus_tag="LP433_001548"
     CDS             complement(2976..4712)
                     /locus_tag="LP433_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBL2005718.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4709..5413)
                     /locus_tag="LP433_001549"
     CDS             complement(4709..5413)
                     /locus_tag="LP433_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2005719.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5544..6047
                     /locus_tag="LP433_001550"
     CDS             5544..6047
                     /locus_tag="LP433_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBL2005720.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6007..6345
                     /locus_tag="LP433_001551"
     CDS             6007..6345
                     /locus_tag="LP433_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBL2005721.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6366..7784
                     /gene="ffh"
                     /locus_tag="LP433_001552"
     CDS             6366..7784
                     /gene="ffh"
                     /locus_tag="LP433_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBL2005722.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7896..8474
                     /locus_tag="LP433_001553"
     CDS             7896..8474
                     /locus_tag="LP433_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBL2005723.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8478..8999
                     /locus_tag="LP433_001554"
     CDS             8478..8999
                     /locus_tag="LP433_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2005724.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9078..9632)
                     /locus_tag="LP433_001555"
     CDS             complement(9078..9632)
                     /locus_tag="LP433_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL2005725.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9885..10160
                     /gene="rpsP"
                     /locus_tag="LP433_001556"
     CDS             9885..10160
                     /gene="rpsP"
                     /locus_tag="LP433_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBL2005726.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10172..10423
                     /locus_tag="LP433_001557"
     CDS             10172..10423
                     /locus_tag="LP433_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBL2005727.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10548..11339
                     /locus_tag="LP433_001558"
     CDS             10548..11339
                     /locus_tag="LP433_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005728.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11509..12030
                     /gene="rimM"
                     /locus_tag="LP433_001559"
     CDS             11509..12030
                     /gene="rimM"
                     /locus_tag="LP433_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBL2005729.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12020..12781
                     /gene="trmD"
                     /locus_tag="LP433_001560"
     CDS             12020..12781
                     /gene="trmD"
                     /locus_tag="LP433_001560"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBL2005730.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12917..13264
                     /gene="rplS"
                     /locus_tag="LP433_001561"
     CDS             12917..13264
                     /gene="rplS"
                     /locus_tag="LP433_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBL2005731.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13522..13815
                     /locus_tag="LP433_001562"
     CDS             13522..13815
                     /locus_tag="LP433_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBL2005732.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            14658..16985
                     /locus_tag="LP433_001563"
     CDS             14658..16985
                     /locus_tag="LP433_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2005733.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            17111..17440
                     /locus_tag="LP433_001564"
     CDS             17111..17440
                     /locus_tag="LP433_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL2005734.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            17480..18484
                     /locus_tag="LP433_001565"
     CDS             17480..18484
                     /locus_tag="LP433_001565"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2005735.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            18481..19910
                     /locus_tag="LP433_001566"
                     /pseudo
     CDS             18481..19910
                     /locus_tag="LP433_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            20116..21288
                     /locus_tag="LP433_001567"
     CDS             20116..21288
                     /locus_tag="LP433_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2005736.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(21450..21905)
                     /locus_tag="LP433_001568"
     CDS             complement(21450..21905)
                     /locus_tag="LP433_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005737.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            22495..22917
                     /locus_tag="LP433_001569"
     CDS             22495..22917
                     /locus_tag="LP433_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005738.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(23083..24276)
                     /locus_tag="LP433_001570"
     CDS             complement(23083..24276)
                     /locus_tag="LP433_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2005739.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            24500..24877
                     /locus_tag="LP433_001571"
     CDS             24500..24877
                     /locus_tag="LP433_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2005740.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            24865..25203
                     /locus_tag="LP433_001572"
     CDS             24865..25203
                     /locus_tag="LP433_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2005741.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            25337..25780
                     /locus_tag="LP433_001573"
     CDS             25337..25780
                     /locus_tag="LP433_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBL2005742.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            26042..26857
                     /locus_tag="LP433_001574"
     CDS             26042..26857
                     /locus_tag="LP433_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2005743.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            26867..27529
                     /locus_tag="LP433_001575"
     CDS             26867..27529
                     /locus_tag="LP433_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL2005744.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            27734..29398
                     /gene="alsS"
                     /locus_tag="LP433_001576"
     CDS             27734..29398
                     /gene="alsS"
                     /locus_tag="LP433_001576"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBL2005745.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            29411..30121
                     /gene="budA"
                     /locus_tag="LP433_001577"
     CDS             29411..30121
                     /gene="budA"
                     /locus_tag="LP433_001577"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBL2005746.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            30251..30748
                     /locus_tag="LP433_001578"
     CDS             30251..30748
                     /locus_tag="LP433_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBL2005747.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            30933..31193
                     /locus_tag="LP433_001579"
     CDS             30933..31193
                     /locus_tag="LP433_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005748.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(31555..31794)
                     /locus_tag="LP433_001580"
     CDS             complement(31555..31794)
                     /locus_tag="LP433_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005749.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            32080..32394
                     /locus_tag="LP433_001581"
     CDS             32080..32394
                     /locus_tag="LP433_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005750.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT        10973 a         5717 c         6485 g         9363 t
ORIGIN      
        1 agagtcatcc aattttcctt taataaactg cgcttgaacg cctttatatt ctttttcaat
       61 cagccattct tcatcaaaaa ataaatgttt atctgttaat ccgagtaatt ttctagtatg
      121 attatccatt gagagactcc tttggtagga tgacgttttg gtcgactaaa ttttaccaaa
      181 agtgagtctc tttttgagtt gaaacgaaga aaaagtgtta gtagaaaatc gccttcgatt
      241 ttccaccaac acaaaatatt atagaaccct ttttttttgc tatatgacag gaatgaaagg
      301 tgtttgcaag cttaatgtga ggaacacttt ccatatctgt tctatactgg ataggagaag
      361 tttggaaata tccagaaaac gaaatcaatc gaggtagcca catgaagaat aaatggataa
      421 atcgaagtaa aaaaaagaaa gtaacacaaa gatcatcaga taaagtcatc cgtctttttc
      481 catcgtataa agaaggatta acggcagatc aagtcaagga acgaatagaa aaaggtgcag
      541 caaataattc agtcgatccc acattcaaaa caaatcagca aatcgtattg gaaaacatat
      601 ttacgtattt caatttgatc tttcttatct tagccatttt gctttgttta gtagaatcct
      661 ataagaactt gactttttta ccagttatca tagccaatac aggaatcgcc atttttcagg
      721 aaattcgatc caaaaagatc ttggacgaac taaatgtttt aaatacagca aaagtcaatg
      781 tcatacgaga cgggatagaa caaacaatag atatagaaga ccttgtaata gatgacattg
      841 ttattttaga gactggatat caaattccag cagatgcaga ggtcgtggaa gggaaactgc
      901 aagttaatga ggctttattg acaggcgaag cagatgaaat aaccaaagaa ataggtgatc
      961 cattaatgtc cggcagtttc attgtttccg gaaaagctta cgcccgatta gacaaagttg
     1021 gagcagattc gtatatttcc cagctgacag tcaaagccaa gacaatggga gaaggagaac
     1081 agtcggagat gattgcttct cttaatcaat tgatcaaatg gattgggatc atcattattc
     1141 ctatcggtat cctgcttttt tctcaaagtt acttttttaa tggaaacacg atcaaagaaa
     1201 gtgtcgttgc aatggaagca gcattgatcg gtatgatacc tgaaggactg tacttgctga
     1261 cgacgattgc attagcatta agtgcgacta aactagcaaa gcaaagagtt cttttacaca
     1321 atatgaaaag cattgagaca ttggcaaggg taaatgtcct ttgtgtagat aaaacaggaa
     1381 cgatcacaga aaataaaatg tctgttcaaa aaatgatcgt ctctaaaaaa caagaaataa
     1441 tcagtcagtc agatcaattg gaagcatgca ttgctgacta tgcaaaagcg atggcaggag
     1501 acaatgcaac aatggaagct gttaaagcat attttacaaa aaccactgat caatcctatc
     1561 accatgttat tcctttttct tctgtccaaa aattcagcag tgtagcgttg gcagacaagg
     1621 tgtatgtttt aggagcgccc gaaatggttt tgcgcgatca attgccggaa tatgcggaag
     1681 agtttgtttc tttcgctgaa aaaggctatc gcgtgttggt ctttggtgtg tacgatggga
     1741 ttcttgaaga accagtattg acagaagcag tcacaccatt aggctatatt ctgattgcta
     1801 atcctatcag aaaagaagca agagccacat ttgattactt caaaaaacag caagtagcca
     1861 tcaaagtgat ttctggagat aatccgctca ccgtatccaa tgtagctgtc caagcaggga
     1921 tttcacatgc tgatcagtac gttgatgcat ctaaattatc agaagaagaa tatgaagcag
     1981 ctgtcgaaaa atatacagtt tttggacgcg tcaagccaga acaaaagaaa atcttcgttc
     2041 aattgataaa gcgtaacaat acagtagcta tgacaggtga tggcgtgaat gatattctag
     2101 ccatgaaaga agcagactgc agtatagcga tggcttccgg aaatgaagcc gccatgcagg
     2161 cctcacaagt ggtcttactt gattctgact tttcacgcat gccagaagtt gttgcagaag
     2221 gacggcgcgt tgtgaacaat attgagcgat cagccagctt gtttttagtg aagaatattt
     2281 tctccttttt gctctcactg ttttcagtga tctttgctct gacctatcct ttagaaccat
     2341 cacaaatcac attgattagt ttgtttacta tcggacttcc atctttcttg cttgctctag
     2401 aagaaaacaa aaagcgaatc agagggaaat tcatcatgaa tgtgatggaa aaagctgtgc
     2461 caggtggact aacagatatg atcgtagtcg gtgcgttggt gatctgcggg gtgactttga
     2521 atctaaataa aacagatgtt tctacagcat ctaccatgct tttgattgca gtagggttcc
     2581 tcgttctcta taaaatctgt tcaccgctga ataaattcag aagtcagatc attcttttct
     2641 gtgctagcgg taactttttt tcggtcatct ttttgcataa gctgttttca atcaccggta
     2701 tctcagctgt atcacttttg ctgttgagca ttctattttt ctcggcagat tcgattttta
     2761 ggcatttgac cacattggta gaatatttgt ttgaacgtaa aaatgaaaaa gagcaaaagc
     2821 cgtttagtcg cgtagctaaa aaatttctat cgatatttaa acgagaaaat tgacgaaaag
     2881 tatctcaaaa aagagtaaaa aagaacaacc actcgtgtat ctttcgaagc aggatgagtc
     2941 atccaacttt aaaacgcacg agcagttgct cttttttaca ttttcggaat ggtaacggtg
     3001 aaagtcgaac ctgttccaag atgactgtct acagtaatcg taccattaag gagttgcacg
     3061 tagtctttta caatcgctaa ccctaatccg gtcccgcctg aatgtcggct tcgcgccttg
     3121 tctacgcggt aaaaacgctc aaagatccgt tcctgatcct caatgtcgat acctatacca
     3181 aagtcttgga cagaaaacga tagatcatct gttgcctgat agcggataat aatctcgctg
     3241 tcgctttttg aatattggac agcattttca atcagatttt tgataattgg ataaaggata
     3301 tctgttttag tagtaaatgg ttcgttcttt ccaatcaatc gaatcgtcaa ccgtttcttt
     3361 tcgatgattg gctgataatt ttgaacgatt tgctggaaat aaggttctgt ataaattgtc
     3421 tggatctcgt aagaattctc gccatctttt gacagctgga tgatttcccg aatcagttta
     3481 tctaaccgga tcgcatcttt ttgcatgatc tcaagaaaag aagtcagagt ttgcgggtca
     3541 tcttttgcac catccagtaa agtctcggta aaaccaatca gtgaagtcac aggagttttt
     3601 aattcgtgag agacgttgcc aacgaaatcc ttttgtagct tttctaaacg tcgcactttc
     3661 gttaagtcat acgccacccc tagaatctgt ccggtacctt ctgaattagt aaagtagcgc
     3721 aaactcaagt ctaatgtctg ccgaccttct gtaagggtga tctcctgatg gatcagcgga
     3781 tgctcaggag tcacttgatg aatcagctga atgagttttg gctcttgaat gacttctgtg
     3841 taccgctgtt caggttgata gcttaccacg tttaaatgta gctgcatctt tggattaagc
     3901 agtagtaaac gagaatcagc atcatcaatc aggaatacgc caatcatcag ttcgttcagt
     3961 aacgtatata attgctcttc tgtggtagta cacgcccgat acatcttact catttgttcg
     4021 ctcaacgcat taatcgtctg atacaattct tcccattgat cgggtgtttg catgattact
     4081 tccgcctgat taggattttg caccattttt tttagtacgg gcagcacggt tttcaatggc
     4141 tggttttttt gatagatcag ataatagatc attcctgcaa gaacaaggaa gaaagacaga
     4201 aagaagaaaa agacccaacg gcgaaaactc tcagttctcg gtaaaaaaac gcttgtcggt
     4261 tctgcgatac gtaaaatggc ttctaactgg ccactttttt tgactggtaa tgcgacatat
     4321 aaaagatcct cattcaaagt agtacttttg cgcaaagcgc tacctaggtt cccaccattc
     4381 aatacggctt tgatttcggg acgggagttt cgctgttcat tcaatgtttc attgtttgtg
     4441 tcaaataaga tctttccagt agcatccatt aaagtaatcc gttcgttcga ctgatggacg
     4501 aattcttcca aagcagtttt gttttgcgct gcttggaggt tttcgacatc taattgccgg
     4561 atcagcagtt gtgctttttt tgtcaggtag ctttcttgct gttccacgat ctgctgttga
     4621 aaataatggg aaatcaattg ccagccacca aaaaacaaac taactaaaag aataagaaag
     4681 aagagacgtt cataaatttt tttccatttc atcgtttggg ttcctgaaac ttatagccaa
     4741 atcctctaat agtcaccaag tactttgggt gttttggatc tcgctcgatt ttttctcgca
     4801 aatgactaac gtgtacatct acgattcggc tttgtcctgc gaagtcaaaa ttccaaatgc
     4861 ggtctagcaa tgtgtctcgg tcgatcacac ggtcttttcg tttcatgaaa taaacaagta
     4921 attcaaattc tttcggtgtt agttcaatca gatggtcgtc tacggtcact tgataattgg
     4981 tcaaatcagc agtgatttgt ccaatcgata gatattcagg ctcagcttca tcttttgatt
     5041 gcttacgagg ttcaattcgt ctgaatattg ctttcatacg ggctaatact tcgcgaggac
     5101 taaatggttt ggtcaaatag tcgtcagcac ctatttctag gccaatgatc cgatccactt
     5161 ggtcatcttt agccgtcagc atcaaaatcg gtgtttcatt tttttcttga cgcagccgct
     5221 gagtgatctc catgccatcc atcgttggaa gcatcacatc taaaatgatg aaatcaaatg
     5281 attgttctaa tgctaattct aatccttcgc ctccatctgt ggcactggtt accttgtagc
     5341 cttctttttc caaattgaac gtcaagagcg ttacaataga aggttcatca tcaacaacta
     5401 gtattttttt cattcaaatc tcctttaaat aggtttcatt ctgtttatat tttagcatag
     5461 aatcagtaca aagggctatt ttacaaaaga aataaatggt ataataggaa ggcactttgc
     5521 tgaatagaaa ggaagagcag tcaatgattg gaatcagtgc atgtttaggc ggtctggcct
     5581 gtcgctatga tggacagaaa aaagaagtac cagaattgat ggaactagtt gaaactggag
     5641 aagctgtcat ggtctgtcca gaagtgatcg gcggattacc aattcctaga gatcccgctg
     5701 aaatcattgg tggaaatgga ttcgatgtgt ggaaagatca agcaaaagta tggacgacaa
     5761 gcggcgaaga tgtaacggaa gcgtacaaaa atggcgcgat caaagcctat caaaaattgc
     5821 aggaaaaaca cattgatcta gtcatcatga aggaaaaaag cccttcatgc ggaacccatt
     5881 cgatttatga cggaagtttt tccggaataa aaaaaaatgg tgccggagtg gctactgctt
     5941 attttattca gcaaaaaatg actgtgctct ctgatgaaga atggctgaaa actagaggtg
     6001 agcagaatgg aaatcgaaaa gaccaatcga atgaacgcgc tctttgaatt ttattcgacc
     6061 ttattgacag aaaaacaaat gaactacatg gaattatatt atgcagatga tttttcatta
     6121 ggtgagatcg cggaagaata cgaagtaagc cgacaagcag tatatgacaa tatcaagcgg
     6181 acaagcaaga tcttggagga ttatgaaaaa aaactccatc ttttttctaa ttatattgtt
     6241 cgagaacagg tattggaaaa tatgactgca tatattacag ataagtaccc ggaagataaa
     6301 aaactacttg aatatgtaca gcaaattcaa gcaatcgaag aataaataaa aggaatgaag
     6361 aaaatatggc atttgaaagc ttaactgaac gtctccagca ggcgatggga aaaataagaa
     6421 aaaaaggaaa agtatcagaa gctgacgtaa aagaaatgat gcgggaaatc cgccttgcct
     6481 tactagaagc cgatgttaac ttgcaagtag tcaaagattt tactaagcgc gtacgcgaac
     6541 gtgcggtagg ggcagaagtg ctggaaagtt tatcacctgc acaacaaatc gtaaaaatcg
     6601 ttgatgaaga attgacgatc acacttggtt ctgaaacagc agagttaaat aaatcaccaa
     6661 aaataccaac tgttatcatg atggctggtc ttcaaggggc aggtaaaacg acctttactg
     6721 gtaaattagc caattattta aagaaaaatg aaaatgctcg tccgctccta atcgcagggg
     6781 acgtatatcg accagctgcg atcgaccaat tgaaagtatt aggtcaacag ctagacgttc
     6841 ctgtatttga tatgggaact gaagtcagcc cggtagagat cgtccgtcaa gggatggagt
     6901 tagcaaaaga aaagaaaaac gactatgtat tgatcgatac ggcaggacgt ctgcatatcg
     6961 atgaaacatt gatggatgag ttgaaacaaa tcaaagaatt gacgcaacca aatgagattt
     7021 tgcttgttgt cgatgccatg actggtcaag atgccgtcaa cgtagctgat agcttcaacc
     7081 agcaattagg tattacaggg gtcgtcatca ctaaacttga tggggatact cgaggcgggg
     7141 cagcactatc gatccgctca gtgacaggcg caccaatcaa attcatcggt tctggtgaaa
     7201 aattgactga cttagaagta ttccacccag atcgtatggc tagccgtatc cttggtatgg
     7261 gggatatgct gacattgatt gaaaaagcgc agcaagacta cgacgagaaa aaagcggaag
     7321 aacttgcaca gaaaatgcgg gaaaattcat tcgatttcaa tgactttatt gaacagcttg
     7381 atcaagtgat gggtatgggc ccactggaag atctaatcaa aatgatccca ggaatgaatc
     7441 aagtccctgg aatcgaaaac gtcaaggtag atccaaaaga tgttgaacgc aaaaaagcga
     7501 tggtttattc tatgacgcca gcagaaagag caaatcctga tctgttgaac ccaagccgtc
     7561 gtcgccgaat tgctgccggt tctggaaaca gtgttgttga agtgaatcga atgatcaaac
     7621 aattcaagga atcaagaaaa atgatgcagc aaatgtccaa aggggatatg aacatcccag
     7681 gtatggacca aatgtttggt tcaggcgtca aaggaaaact aggcaaaatg gcgatgaatc
     7741 gaatgatcaa gaaaaataag aagaaaaaga aaaaacggaa ataagatgaa aaaaacagct
     7801 tcggtacaga ctgaaaatgt ctactgccgg agcttttcta tcagcaattt ttattcttta
     7861 ctaatacaat tactctaaac gaagaggtgg cacagatgag atgtccgtgg agtgaacaaa
     7921 cagaaagtat gcggcaatat catgatactg tctggggtgt tcctgaatat gatgaccaaa
     7981 agctgttccg aaaattgatg cttgatatta atcaagccgg attgagctgg cagacgattt
     8041 taaataaaag tgaagcattc gatgaagcat atgatcgatt cgatatcaaa aaagtcgcaa
     8101 attatggaga aacaaaaatc agtgaactaa tggaaaacaa aggaattatt cgtaaccgaa
     8161 gaaaaatcga agcagccgtc caaaacgcca aagcagtctt gaaaattcaa gaagaaatcg
     8221 gcagtttttc agagtatctt tggtcgtttt ctaatggaaa aatcgttgat tcttcttatc
     8281 attcacaaga agaagtccca acaacaagtc ctctttcaga tgaattagca aaagatctaa
     8341 agaaaagagg atttaaattt atcggaagca caacaatcta tgctttttta gaagctgtcg
     8401 ggatcatcaa tgatcacctt gacagttgtt tccgcaaaga agaggtcgta cgtatcggca
     8461 gaaagggcga ataaagcatg cgaaaaatca tattttatgg tgctataagt ttagatggct
     8521 atttggcaac gaaaacggat gatcttcaat ggctttttga cactccaaca ggtaagcaaa
     8581 ctacttatga agctttttat gaaacaatcg atacgaccat catgggcaga aaaacttatc
     8641 aggaagcaaa aaaatatttg gagaccgaag caatttatcc agagaaaaag aatttcgttt
     8701 tttccaccca cgcacaatta caattgccag atgctgaggt cgtaaacgaa gatcctgttg
     8761 cttttctaaa aaatctacaa atgacagaag gaaaagatat ctgggttgtg ggtggcggtc
     8821 gattgatcaa accgctattg gaacatcaaa tgattgatga atggtatatc cagattaccc
     8881 ctgtattatt aggggacggg attcctttat tccaaaaagg aacatatgaa gcgcgttttg
     8941 aaatgctaga cacgacacga ttcggtgaat ttatcgaatt gcattatgta cgaaagtaga
     9001 agtaaataaa ataaaaaagg caactatatg cagaaatgtc ctgtacatag ttgccttttt
     9061 tattaccgtt atgcttttta ctctgttaat ttgttagaaa aatctagata cgcatctaaa
     9121 atcgtttgga agaaacttaa tgttccttca acgatattac cattttcatc aattagattc
     9181 gcaacgtttc cgatatatgc ttccggttgc tgcaaggttg gcacattcaa aaagacaagt
     9241 gattggcgta gatggtggtt tgcgccaaag ccgccgatcc cacctggtga tgcagtaacg
     9301 actaaacctg gtttatgatc ccaaacactg tgtccataag gtcttgagcc tacatctaaa
     9361 gcatttttca atactgctgg cacagaacgg ttgtattcag gagtaacgaa aacgacaccg
     9421 tctagtcccc tcacttcctc acgaaaacga gtccattcag caggagcctg ttctggagtt
     9481 tcgagatcct cattgtaaaa tggcagatca tcgattttta caaatacact ttcgtaccct
     9541 tcaggaagca atttcgcaaa agcttctgct acttttttgt tgtaagaatc ttttcttaaa
     9601 ctaccaataa aaaatccaat tttttttgtc atacgatttt tcctccttca aactatctat
     9661 aataatctta caaaagataa gtaactggag caaataaaaa cacttactga caaaagctac
     9721 atagaagata gattacttat ttttaacaaa aaagaagtct aaaatcttct attttctaaa
     9781 aaaaatcgaa tttaatcaag ctgtaaagaa aaaaagcttt acagggtaaa aaaaaactgt
     9841 tacactacat cttgtgaata aaacaatgga ggtggaaata aataatggca gttaaaatcc
     9901 gtttaaaacg tatgggttct aaaaagagtc cgttttaccg tatcgtcgta gctgattcac
     9961 gttctcctcg tgatggacgt ttcatcgaaa ctgtaggtac ttacaatcct ttgaaagacc
    10021 ctgcagaagt agttttaaaa gaagacttag ttcttgactg gttatcaaaa ggtgcacaac
    10081 cttctgacac tgtacgtaac atcctttcaa aagaaggcgt tatgcaaaaa caccacgaag
    10141 ctaaattctc aaagaaataa ggtgaccgga tatgaaagat ttaagcgact tagtcttaac
    10201 aatcgttcgt ccgctagtca cttatcctga tcaagtcaag ttagacgtcg tagagtcgaa
    10261 agacttttac gagtacaatc taacagtggc tcctgaagat attggccgta tcattggaaa
    10321 acaagggcgt gttgctaaag caatccgcac aatcgtttac ggtgttcgga tcaatgcacc
    10381 gaaaaaagtg cgtttgaata tcatcgatga taaggaaaag taaataaacg tgctgtactc
    10441 gaattttcga gtgcagcttt tttgtttttt ttattaattg aagaaatgat tatttggcaa
    10501 aacaagcaag aaagcgtatc cttataggag gagggagtga acagccaatg agaaagaaaa
    10561 tgttatttat tccatttgct ctattgttaa gcgcttgtag ttcggttact caagaatcag
    10621 acaatacaca tctatcaagc agtatatctg aaactgttac cagtccagaa aaaagtagta
    10681 ccaaaacggc ttccaccact gaacaaacaa tggctacctc aaataatgag aaaaagactg
    10741 ctttagacca gttgaaagaa caacagccaa atgttcccat gcctctagat gtaccagtct
    10801 cttcaggcta tctcaatatc gcagcgacac atacaaagca aggttattct attttatatt
    10861 acagaacaga tcgtcccctc gggttgaatg ctgacgaatt gaatcaagaa acgcctattg
    10921 caacctatct atatcaatat gggtttgctt ctagtcaaga aacaatccaa gttttgcagc
    10981 catttgagat cgacacaaat ggtcagcaag tggacttagg ttctcgaatc acagggtatc
    11041 agcaaggtgc agcaggttca agttttcttg aatggcaaga aggaaactgg cgtattcgaa
    11101 tccgtgggaa taatatagaa ggccaagatc ccttactatt agctaaagaa atcgtagctt
    11161 atttggaaga aaacagtcta ccagcacctg aacaatttgg taaaattact gttgatatgg
    11221 gtgatacgac gaatcgagcc gtagaagtaa gctggcaaga accgaaaaat gcctatacga
    11281 tcactcatca agatcctatg tctgcgttga agatggcagt ttctatgaag aggttgtgaa
    11341 atcagcgcgc tgatctgagc ccatcattta actccaagtc acaggaagta atcaaaaata
    11401 gcacgccgca tttttgcata attttggctt aataccttaa aagaaaacta gaattgcctc
    11461 ttcacacatg ctaaaataaa acagacaaaa aagaaatggg gatataagtt gactgaatac
    11521 ttgaatgtag gaaaaatcgt aaacacacaa ggtatcaaag gcgaagtccg tgttatctca
    11581 acaacggatt tcccagaaga acgttacaaa aaaggaacgg tgctaacact attccaagac
    11641 ggaaaagcac ctgtggaatt aacagtcaaa agtcatcgca aacataaaaa ttttgactta
    11701 ttgagttttg aaggacatcc ttctatcaat gatgtggaaa aatatcggga tggcatatta
    11761 aaagtgtcaa aagacaactc tgtagatcta gctgaaaatg aattctatta ccatgagatc
    11821 atcggtctgc atgtattaga agatggaact gagttaggta aagtaaaaga aatcttgtca
    11881 ccaggtgcca atgatgtttg ggtcgttcaa cgtccgaaaa aagctgatat attgcttcca
    11941 tatatcgctt ctgtcgtcaa agaagtcgat ttagaagctg gagtggtccg tgtagaaatt
    12001 ccagaaggac tgattgacga tgaagattga tgtattgact ttatttccaa gaatgtttga
    12061 aggtcctatg ggggaatcca tcatcggtaa ggctgtagat aaaggattat tagatatcaa
    12121 tatctctaac ttccgcgatt attcagataa caaacatcag acagtagatg attatccata
    12181 cggcggtgga gcaggtatgc tgctcaaagt ccagcccatc tatgataaca tccaagccat
    12241 tgaaaaagct gcaccggatg tcaaaaaaag agtaattctt cttgacccag ctggtaaacg
    12301 attcgatcag aaaatggcag aagaattttc acaagaagaa cacttagtat tcatttgtgg
    12361 tcattatgag ggatatgatg aacgtatccg cacattagtg acagatgaag tttccttagg
    12421 agattatgtc cttactgggg gagaattagg tgcgatggtc atgatcgatg caacagttcg
    12481 gcttttgcca gatgtgttag ggaatcagac ttcagctcaa acggattctt attcaaccgg
    12541 tttattggaa catccccaat atactcgccc ggcagaatat aaagggatga aagtaccaga
    12601 agtattgaca aatggaaatc ataaattgat tgaagaatgg caattaaaag aatcactaag
    12661 aaggacctat caacgtcggc ctgatctttt ggaaacactt gaatggacac ctcaaatgac
    12721 gaaattttta gaagaaatca agaaagaaga acaagaaaaa acagcagatg aagccaagtg
    12781 actttttcta aaatcttctt tacagtaggt tgataatatg ttagtatttt atggtgagtg
    12841 caaaagcact taactattac gatattccgc tgtgagaaaa gctcataaga atatttggaa
    12901 taaggagaag aaaaccatga atccattaat cgaagaatta acaaaagaac aattacgttc
    12961 tgacatccca gcgttccgcc ctggtgacac tgtgcgtgtt cacgcaaaag ttgttgaagg
    13021 tactcgtgaa cgtatccagt tatttgaagg tgttgttatc aaacgccgcg gtgctggaat
    13081 cagcgaaact tatacagtac gtaaagtttc taacggagtg ggcgttgaac gtacattccc
    13141 attgcataca ccacgtgttg caaaaatcga agtagttcgc tacggtaaag tacgtcgtgc
    13201 aaaattgtac tacctacgtg cattacacgg aaaagctgct cgtatcaaag aaatccgtcg
    13261 ttaatcattg ttatcagact gagaaagaac ccttggtatt caagggttct tttttcttag
    13321 catgtaattt gaacaccctg atccagtttt ttctttaatt attggtaggg gagaataatg
    13381 gattagaata aatctaccta taagtagtag taaaaaaaag agcactatga taatatcttt
    13441 cttaagagta accgctttaa taaaaaatcc agaatattct aacataaatg gagtattctt
    13501 agaatcaaaa ggagaaagaa gatggtttat acttatacgg agcaagaaaa gatgaaagtt
    13561 ttagacacat tcatgaatga tggaaaagta aaacaagtac caagttcaac aaaaaagaaa
    13621 tacatcctat tgaaagaagt cttgaaacgc tttgaccatg gagtgactta tacagaaaca
    13681 gaggttaatt cgatactgct gaacgtattt tctagtggcg attatgtcga acaaagacgt
    13741 tatctaatca catttggctt tttcaaaaga agttcagacg gtcgggcata tcagatgatg
    13801 ggaattgaaa attagaagtt ttaatttata ctcattgaaa aaagttcaag tatgcgatat
    13861 tggttctaca ccgcatactt gaactttttt tgtcatctgt atctataata caaagccaag
    13921 aacgttattc aaaatatgga tagctatgat aaaagctaat gagcgattcg cagttaaata
    13981 agcaatcgtc agtaaaatcg ttccaggagc gtacatgaaa aaatcaattg gatgcgttac
    14041 atgaataaag ataattctct tttatttgta cgaataaata ccaaaacgta cctcctaaaa
    14101 ttagattttg gacagatgcc ctttaaaaag ataacaagat ttcgttcttg aaacaatata
    14161 tatgctttta ttccaatgag gttgtgaaaa cagtattttg tcctgagcgt tagaaaattg
    14221 aaaatgggga atagcaactc gtactttacc attttttaag tgaatacaag atcagctaat
    14281 tgaacaccgt ttattcgtga tgagggacac aacactgcag tcgacacatt tctcttttat
    14341 gttcaaagat aacaaatatt taaaacaaag aaaaatagta gataatcccg tcctaactct
    14401 tttattcttc cctcatagct tccaaattta agcaatactt caattaatca agttttatct
    14461 ttttttttca ataatcgtaa aaaaagagta ttttttattt aaaaataaaa tctttgtatt
    14521 aaaggacaag actaaaataa ccttagaata aaaagagaaa aaaagcccca aactttctat
    14581 acatcaataa aataataaaa attaaattta gaataacgtg taaaggatta tttgatgatt
    14641 ttttattgag aggagggatg aaaatgatta agaaaactca aaataaaatc caacgtatat
    14701 gtcaaaaaca ttttgtttct agactcaaag ctgtatctaa aagaaaatac ttacatccca
    14761 ttatgatttc gatcatcttg atttttactt tcttagggag cttatcaagt atttatgtaa
    14821 acgtttatac agaaacgtca aattttgcta accaaacgac agaggagaca aatagtccac
    14881 cctattctga aatacagtcc atagaaagca ccaatcagtc tagcaacaac gagacaacct
    14941 caaccacatc ctcgactcaa ctgattgatc cgacagaaaa agaaatcaca gcagcaaaag
    15001 cagcagggga gaaagcttat tcagaaacag gtagaagcca gacatttagt actgttgcgg
    15061 ccactgcgaa tttcaacgga cataccatac cagatggata tacagtgata tatgccaaag
    15121 atggagtcat tgttgcggtt aacggatcga tgagtgcgga taaaactgcg ttacaaggcg
    15181 taaccaaagc aatcgctttt attgataacc gtccagatat ccataatctg tttattggct
    15241 ccacagtaaa tggtactact atcacattcc caaaaagtat ctatatgggg gtggctaccg
    15301 ctggaaatac gatcgattca gttacaccca atgcggataa aagttattct tttacaccct
    15361 caacatgggg agggcttcct gccggaggag gtatgagtac tttttcaatc ggtatacagt
    15421 tagcaaatga tattccattc acggggtact cgatcaaaaa tgggcagatc gttgatggta
    15481 agggaaatgt ttcaaatttt ccaacctatc aagcagcaac ggttcaggtc aatgcgaatc
    15541 ggacaggaac tttttcttat acagtcaatg gtggagcagc aaaaatcgga acgtacggga
    15601 ctacattatc tggaatccat gtgggtgaca aagtggttat cactccaaca gcagtaacgg
    15661 gctattcttt tgcacaaaca aacggttctt tcacagccct agaaagtaac gtcgatacgg
    15721 tgacctatac aggcaaacaa acaccaatca ctattaagta tcaagactat tttggacaga
    15781 tgattgctcc ttctaaaata atgaatctta cttacggaag tgctgcacaa gacctgacga
    15841 ctaatacgcc tactatcaac ggatatacct ttacagctgt ttcagcgaca gaaacaaaga
    15901 accaatcagc aatgagtgtt ttagctagtt tagatacaaa tggaaatgta atcgtaaagg
    15961 acgcaaatgg aaaacagatt tctgaagtca tcctatatta taagacaaat gcaacagtat
    16021 caatcaatgc aaatggcagt aagtactatg atggtctttc tgttgtaccg atcgttaaat
    16081 atgcctttaa tgataaaaca gaatcaacat cccttttaaa caatgatctc agtattgatc
    16141 aaatcacatg gaatccaact gatttcaaag cgatgaatga aaagggagtt gaagtaactg
    16201 cgcctactga aattggaacc tatacgtctt ggcaattgac aaaaagcgga ctagctaaac
    16261 tagctgccag aacaaactat ttatttacta tcgtgcagac atctgatgtc tatacgatta
    16321 agcaaatcag cggtgcggta gagctcagtg gcagtaagac atatgatgga aaagcaggtg
    16381 tcccgtcaat ccatgtcaag ctagcagagg gtgtcactag ttcgcttact ccagtacaag
    16441 tggcacttag cagtatggat tacacagcag atgcacaatc agcaaaaaat atggttaatg
    16501 ctggcagcta tacaattaaa ctaacgaata gcggaataga caaagtcaaa gcagcaaatc
    16561 ccaagttgtc atttactgat atagccaaca catcaggaac ttataccatc tataaagcta
    16621 acgcagtgat tactgtcgat gacgctgcct ttaattatga tgcccaaagt cactcgattt
    16681 cggttggaaa tctccacgtt accggtgttg tcttaggcga atcattggat tataccctaa
    16741 cagttaacag ccggacagat attggatcac aaatagtaac gattagttta ggcgaaggaa
    16801 gtgtaaacaa taattatacg attatcgcaa cagataccgc taagttgacg atcaatccga
    16861 ctctcttgct tccttcgaca ggtgggatag gtctactgcc ctttgtcttt ttaggactga
    16921 tctttatttt ttctggcttc ttttatttta tccatcgtaa gaaaaaagca ggtgaacagc
    16981 gatgaaaaaa acaaaaaatg tacgtgtgga tatatttgct gttctctttt ttatcctact
    17041 ggtctttttt ataggttctc cgactgtgtc agctagagaa tcacctatta catttacttt
    17101 gcataatcga atgttcgaaa gcgataagat gccaagtatc agtcaaaacg acggaataaa
    17161 tatcccggat aactttcaag gagtaaaagg gttgaacggc gttactttcg ctatatatga
    17221 tgtctcggat gaattttaca agctgcggtc agaaggaagt agtgtggaag acgcacaaag
    17281 aaaactagca caaaaaagtg atagtgaaaa aatactggca gaaaatgtga caaaaacagt
    17341 agacgaggaa gagggcattg cttcttttag tgcatcggac aaagatgagc aaggtcgtga
    17401 cgctgtttac cgatttgcgg aaataaagac ttcagattaa gtaaaagaaa aatcagcacc
    17461 atttgtcgtt gtgcttcctg tgacagattc atctaatcat aaattgacga ccatccactt
    17521 gtatccaaag agcgaacaaa aaatacctgc tgcactcaca ttaacaaaaa cagtagagaa
    17581 taagcagaca gattttgcag atggggataa agttccttat ctcatcaccg taacaattcc
    17641 tgagaacatc aacgagatag gaacctatac gatcaaagat acagctgatc ctcagttatg
    17701 gctagaacca gaaacgatcg attttttgat tggtggagac aagattcata catttcacac
    17761 acaaaaaaca aaacatggtt ttgtcttatc agattctgga aaagatctta gttcgtttgc
    17821 tgggaaaaaa ttaacgatcc gttaccaaat gacattgaaa gaaaacagtg aaaaaacgac
    17881 atttgataac gatgtacgtt tgacgactga caatcaaaca gtagaaacac atcttgccat
    17941 ccaaacagga ggcaaacaat ttgtcaaagt ggatcggcaa acgaaacaaa aactagcaga
    18001 tgctcaattt ctagtcaaaa aaaatgacca atacttagcg caagaaaacg ggataaatca
    18061 ttgggtagcc aaagatgatt caagagcaac gatttttact tccagtaaag atggaacatt
    18121 ttctgtccat ggattgtctt ttggaagtta cgaactagtg gagattaaac cgcctaaagg
    18181 atatatattg agtcaatcaa ccattctctt tgaagttgaa aaaggcagtt atgatccgct
    18241 tcatcctata ccattggaaa tcatcaacga accaaaagca aatccgacga ataatggaaa
    18301 aacgccagtt cagatgcaga caaatggtcc atcaaatgaa aaaaatggag gaagctttcc
    18361 aaaaacaagc gaagagatgc ttggaggttt ctcaatttta gggttgttgc tagtcctttc
    18421 aacagggaca gcttggtttt ataaaaaaca acaaaaagga aacaatagga gggaaataaa
    18481 atgaaaaaca tcaaaacaaa aatatggacg tttttaggaa ctgctatcat gctgcttcct
    18541 ttcgttctcg gcctaggaac tgcagaggtt tctaggccgt atcacctaca ccagaaaatg
    18601 ttacggttaa tttgcataaa ttgaaattca cttcagcacc agaaaatcaa ataaacaacg
    18661 gaacggaatt gacatttccg aatagcgaac cgttgaacgg cgttgaattc aacgtatatg
    18721 acatcactgc tacgtactat ccaagtaaag acacagcagt tccagcagac gctacaccct
    18781 tcgcaagtgt aacgacttct ggtgaaggat tagctaacct gactcttcca ggtaaatctg
    18841 atgggaaaga tgctgtatac gtctttgtag aaacaccaaa gcccggtgtc gaaacgtcgc
    18901 caaatatcgt gttaagctta cccttttata acccgaattc atcagaccct gacaaacctt
    18961 tagacacgat tcacctatat gctaaaaatg tcatcaaaga aagcaatatc aaaatccaga
    19021 aagctgggaa cttttcaggg gtagataagt tagcaggggc gcaattccag atcaaaaatt
    19081 cagagaatca attcgtgacc ggttttgatg aaaacactgg tgtcgctctc tatgatcctg
    19141 ctgagtcagc gttgacattc acaactgata ctgaaggatc catcagtgtc aatggattaa
    19201 tagacggcaa ttatacttta gttgaaacaa aagcaccaga tggttatcaa ttaaccaatc
    19261 cacaaaaaga aactactttt atagtaaaaa acggaaaatt gcaacaaaca accggtatca
    19321 tccatggcgc agatgaagcc aatcttggga atccaaacgg tgtagtcaat cgggaaaata
    19381 caactacgga taacacgatt actgtagaaa atgtccaaaa ctacggtgat ttccacttca
    19441 tcaaacaaga tgtgaacacg caagaaaaat tagccgatgc agaattttct attctaagag
    19501 caaaagatcc aactgttaaa ttaatgaaaa aaatagcaaa tcttgcctca ggagaatacc
    19561 catatgcttg gtcagatgaa gtcacaggtt ctgactggga agaagtgaaa ttgatttctg
    19621 attcagaagg gaaattttca atcgaagggc tgaaacaagg ggcatactgc cttcaagaaa
    19681 caaaagcacc agaaggctac gcattaccta agaatgaagc tgcgtacact gaatttacag
    19741 tagatgatga tccaacaact tctgatgaaa caacgatcga taaccaacct aaaggaatct
    19801 tgccttcaac tggtggtatg gggatcatcg tattcatctt ggtaggtact gctttagttg
    19861 gaggagcagt gatctacttc aaaaaacgcc atcaagaaac agaagcttaa actattggaa
    19921 acaaaaatca tacgataaat aaacgatagt gattcaaatg gggagaaagg ttgtgacaag
    19981 tggtcggtct cttggtattc gctcaacaaa cggcaaaata ggaggaacta ttttgccgtt
    20041 tgttgagcga atactcaggt caaggcgctg atttcacaac ctcttcatat acatattaga
    20101 aaataggtgg acatgatgaa taaaagcaga ataagaatac tggacatctt catggcaatc
    20161 attttagtcg ttgggatcgg gatcttttct tatccttttg tagaagattc actgaatgat
    20221 tttcttgccc agcaaatgat catccattat caaaagcaag catcgaataa gaattcagag
    20281 gaaataaaaa aacagcagga aaaaatgaca aagaaaaacc aacagttggc agagcaaaac
    20341 gtatcaccag ggataggcag tttcaaccaa gcagttgatg caaaagcatt aaaagattta
    20401 cctagtaatg ccttttttat ggaacatatg cttggagtca tcgaaatccc aaaaatcaat
    20461 gtcagcttac ctatattcga tcagacaacg gaaatatttt tgcaaaaagg aacgtcatta
    20521 ttggaagaaa gttcttatcc gactggcggg aaaaacaccc atgccgttct ttctgggcat
    20581 cgtggactcc cagaagcaaa attatttaca gatttgccta agttgaaaaa aggagaccag
    20641 tttttcatcc agatcaatgg aaagacattg gcgtatcaag tagaaaaaat ccaagtggtc
    20701 ttacctgatg aagtagattc tttgggtatc caaaaaggca gagatctcgt gactttgctt
    20761 acctgtactc cttatatggt caatacacat cgactgcttg tgacggggca tcgtattcct
    20821 tatcaagcaa aagaggcaaa aaaagcgatc caaggaattg atcaatggaa aaaatggaaa
    20881 ttttttattt ggtttatcgg tatactactt ggatcaatcg gcttagtttg gctactcatc
    20941 gcttatttag attctttggc catcgctaag cgaaactatc ctttatcttt ttatgtaaag
    21001 aacacaaacg gacgaccaat cgaaggaatg gtcttttctg taaaaacgct caacggcaaa
    21061 cactatatta ctagagaaaa agttccattt gtgaaagctt ctgatgaata cggactagtg
    21121 agattttctg atttaaaagg caggaactat cgcttgcaac atgaggagct cctgcttaaa
    21181 atccatgtaa aacataaaca ttcgaaacag ttttcaatga aattgaaaaa aggaagatat
    21241 aaactgcgaa aagaaaaaga ggtgtactat ttgattgaga aagaatgaat gaagatgtcc
    21301 aaaaaagcag agggaacaga ctaaatgaaa aaagagagaa gctgacgaaa tggacgtgta
    21361 aactgctatt tttggtttac tatctggaac gccagcttct atttttttat gtttcagaag
    21421 aattttatta ttatagtata acttttgaat tagtttccat aacatttgga gcaaggggtt
    21481 aaaccacgag cttgagcttc gcttaaagtg gcaggggtat acgtaccatt tccacattta
    21541 tgtgtatggt attttgaacc ggtcggtgtg acatagacag tttgttcatt attttgctca
    21601 ggagctgcgg cttgtgcctg ctgagaggcc tgttcagctg ctgcttgctg tcgcgcctgt
    21661 tctgcttgtt gctgtgcgat tgcttcttgt tgcgcttgtt ctgcttgttg tcgtgcaatt
    21721 tcttcttgct ttttccgttc ttcttctgct tcttttgctt tgattgtgga atcaattgca
    21781 gcaagacggc ttgtcaactc ttgtttgttt tcaggtagcg cttggatagc tgctgaagca
    21841 gttgcatagt tttcttttgt aggatttgct tcagcttgtg acaaagcaga ttccgcttct
    21901 gtcacttttt tttctagtgc agctttttcc gctttttgtt tctcttcttc ttttttcttt
    21961 tcaatttgtt cttgttcttt cgatgaatct gccgtacttt cggagatcgt ggtactgctg
    22021 ctggaagcct gagctgaact tgtgctttga gtagtagacg tagtagcacc acacccactc
    22081 aacaaacttc ctgcgaccaa aaacaatgca actaattttt tcactaaatt tcctccttaa
    22141 gtaaaaaaca accgttttca ataaatgtcc ttttcaattg tttacttact tgttataata
    22201 attgtgttat gaatagtgat tgaggaaact taatctaatc ccgttttgat acacgggatt
    22261 ttttgctata gttctgttat taagtatgca ataataaaat atgtacgtta ttttattatt
    22321 agattattga catttatata ataaacgatt aaatgattca tatcaataga atacttagga
    22381 aaaaaagaga aataataaca ggtttatgca ctattgacgg tgtgacaata tgatatttgt
    22441 atccgttttt tttcttgtat gtagtatagt aaagtagata caggaggaga aaatatgcag
    22501 acttttttaa caaaagtttc tcaaaagaaa attaaaatga ttcatttact gcttgaaaca
    22561 gaacgttggt gttcaataga agaactacaa aacgaattga aggtatcaag taagtctatc
    22621 ttgaattatc taacagattt agaagaattg ttccaaaaat atcctgataa ggtcattttg
    22681 aagaatgaga ataatcggcg cttttctatg gaaaagcagg agaacttccc aatctacatt
    22741 atttatcttc atttctacag aaaatcatat aattatcatt tgattgaatt catgtatcaa
    22801 catcctgaga aaaatttgga agattatgca gacgctcaat atacgagtgt atccacagtt
    22861 tttcgttatg ctaagttatt agtaaagtac tttgaaatga cggacgtcaa agaatagtag
    22921 ccgccagata gaaggaaatt agcagttgaa aaagctgccc tgcatcaagt aatacgacca
    22981 gccaaacgga aacagtgtct catgtttttg atttggctgg tcttattacc gcagatgcaa
    23041 gcttttgcca cacctctttc ttgtcattta cagactcaac tatcaatgct gcaagctttc
    23101 ccttaatgct gtaacaccag taagagttgt caagaccagc agactgacta ggtaaatacc
    23161 gctcaaaaac aagattacgg cagttaaact ataatgatcc atcaagaaac cgatgacgat
    23221 agaagaaaaa ccaccaacag ctcgtccaag gttcataatg aaattattcg ccgtcgcgcg
    23281 gatttctgtt ggatacaaac tactaatcac tgcgccatat ccaccataca tgccattgat
    23341 aaagtagccg actatcacag cggctgctac caaactccac tggctatggg ctaacacaag
    23401 tagatagaca gataaggatg aacaaattaa aaacaaagaa aaggctagtt taggccccaa
    23461 tttatccatg attatgccaa aagtcatcat ccccaaagac atgcctaaaa tagtactgac
    23521 catccacaat gaagacccag aaaccgaaag ccctaatcga ttttgcataa ttgaaggcag
    23581 ccaattcatt aacccaaaat agccggcaat ttggacagtt accatgatac taaggccaca
    23641 tgtttgccaa gcaagatgtt ttgattcaaa cagtctgcta agtttggttt tcttttcggc
    23701 agattgtaca gatttgaatt cctttggttc agtcaagccg cgacgaatga acaagaccat
    23761 caacaccggc agtacaccta cgacatacaa catcttccaa ccaaacgttg gaatgatcac
    23821 agcagctaaa atcgcagcca aagccgcacc gacctgcgca ccaataccag caaccgaaga
    23881 agctcgtcca atttgttttt ttgaaaaact ttcggaaatc aaggacatac acgccccgta
    23941 ttctcctccc gctcctacac ctgcgataaa gcgaaagaga taaaccaagt agatgtttga
    24001 agcaaaatac atcaataaag aagcaatcga aaacagaagg accgtttgag aaaatacttt
    24061 cacacgtcca tatttatcag ctatgatgcc aaaaaaaata cctccaatga gcatccccaa
    24121 attagtgatc gttgaaatga aacccgcttg cgtaccacta atatgaaaag aagtaatcat
    24181 tgaagataat gaaaaagcta aaaacataat atccatattc tctaaagcaa ttcccgccga
    24241 tgtcgataat aataactttc gctgatacgt tgtcattttt ataccccttt tcctaaaatt
    24301 tccctaaatt gttaaaagta tatccaaaaa agaataaaaa aacaagactt ttttatttga
    24361 aataatacac aaacaaccga tatagataat ccagcttagt tttaatagaa atgagtattg
    24421 acttggagta cacttaaagt tgtagaataa ataaaataca taagtaaagt ggcaagaaat
    24481 taagagaaag agtgatcaga tgaatatcaa acaagtcagt gaagaaaagg gcatttcggc
    24541 cgatacattg cgctattatg aacgaatcgg gttgattcca ccagttaatc ggacaaaagg
    24601 cggaatccgt gattatacag aagaagacct aaaatgggtc gactttacga tctgtatgcg
    24661 aaatgccgga ttatcgatcg agtctttgat tgaatatatt cgcctatcta gcgaaggaga
    24721 agcaactgta tttgagcggc gtaagctttt gattgaagaa agtgaacttt tgacgaaaaa
    24781 aattgctgaa atgcaagaat gtttggaacg tttacaagga aaaatcaaga aatatgatcg
    24841 tgtgttatct agaaataaaa tggaatgtat caagtaaaaa aatcaaggag catcgctatg
    24901 gagttacgct tactaaaata tttttggaca attgcagaag aaggaacaat ctctcaagcc
    24961 gcagaagttc tacatcttac acaaccaacc ttaagccgac aactgaagga gttagaagag
    25021 gaactaggaa cagaactgtt tgtacgcgaa aaccgcaaaa tgatcttgac agaagcaggt
    25081 tattttctaa aaaagccgag cagaagaaat tttagattta acgaatcaaa ccactcaaga
    25141 attcgagaac agaaaaaaac aattattcag cggccgattt acgatcggct gtgtggaagc
    25201 tgataattcg aatacattgg cactattact agaaaagttg atccgtgatt atcccagcgt
    25261 tcaatttcat atccacagcg gaacaagtga tgatatcacg gagtgactag aaaaaagcct
    25321 gttagattta gcgattttgc tagatccagt agatacagag aaatacgaaa cgattttgtt
    25381 accaagaaag gaaaaatggg gattgctcat tttagaaaat tctgttttag caaaaaaaga
    25441 cgtgataaca aaagaagact ttgcgaatgt acctcttttg atctcaaagc gtccagaaat
    25501 acagcgaatg tttgctgact ggttaggcat aaaaaaggag cagttgctga tcacaggaac
    25561 gtacaatttg attttcaatg tatttgcgct aattgagaat caggtaggtg ctgctttagt
    25621 catagaaggt gctgtaagtc atctttcaaa gcgagtgaca ttcgttccgc ttgacccaat
    25681 gattgaaacg aactgcatgc tagtctggaa aaagaatcgg attttatcac ctgtagtcaa
    25741 tgaattgatt caccgtttca aagaagcttt tgaacagtaa taagtatctc taatcgaaga
    25801 aatttcaata caaaagcgag acgtatgaca gtcttgcttt tgtatttttt catttttaaa
    25861 tcaaaaaaaa taaagagatt tacataactt gttaaataag cgcttacaaa cataagaaga
    25921 acggaaatga atcagctata ataaccgttg ttctggattg taatcattac aaagaaatga
    25981 agattataac tttggaggtg ttcgaaatga aagaaaaaaa gcaaaaattc gttcaaaaaa
    26041 catgcccttt attcaatggt tgggtatgat tctgctgatt gtattagctt tattgacgat
    26101 cattcctttt ttatggatgg tttctgcttc attcaaagca aataatgaag tgttcacgat
    26161 tccgattcaa tggatcccta aaacttggca tttagagaat tatctggtta tttggtctcg
    26221 tattccttta gtgacatttt ttaagaatac agctttttta agcgttgtga tcacgttgat
    26281 tcagttgttt acttctagtt ttgctgctta cgggttttct aaactaaatt ttaaagggcg
    26341 cgatatttta tttttagcat atatcggaac gattgctgtc ccttggcagt cttatatgat
    26401 cccgcagttc attatgatga gaaaagtggg tttaacatat acgttgtggt cgttggtgct
    26461 attacaagcg ttcaatgctt ttggtgtgtt cttgttgaag caatactaca gtagtatccc
    26521 agattcttta tgtgagagtg cgcggatcga tggcttatca gagtggggaa tctatcgcaa
    26581 gatcatttta cctcttacaa aaccggcgat tgccagtttg acgatcatca cattcgttaa
    26641 tacatggaac gattatatgg ggccattcat ttatttgtct tctacggaaa ataaaacaat
    26701 ccagttaggg ttgaaaatgt ttattgggct atttgatgca gagtacgcat taatcatggc
    26761 tgcctcagtt gtttctgttc ttcctgttgc ttttatattt ttagcgatgc aaaaatattt
    26821 tgtagaaggg atcgcttcat caggaatgaa ggaataggag gtgattatga aagagcagcg
    26881 ttttgacaaa aatgtttata tggaattctt ttattggttg tatcaatcat tggcaagtag
    26941 cctttgtttt tggtgtgtca atatcttgta tatagcagct gcgttccttt tgtcgataga
    27001 tggaaggaat gtcttttcct ttattttttc tttacttttt attggtccag gttgcatcgt
    27061 gatgataggt atgacagaag aattagcaaa agaaaaaagt ttttcaccag tacgtttgtt
    27121 cataaagacg tttcgccaat tttggctaaa gggatttttt tattggctat ttgcttggat
    27181 agttagtgtg ataatgattt ttgattgttt cttttttata cgtttttctt atggaaaatg
    27241 gttgattccg ttgtttgttt tacttgcttg tttatcagtt tcctttagca tcaactactg
    27301 gtattttcag gtgagaaatc cagcgtcgaa accaaatcaa gttctacgga tagcgttcta
    27361 ctatacgttg aaaaaatggt atgtgagttt actagatttt ttactattga caagtttgtt
    27421 tctcttcttt ttcgtaaagc cccaatggtg tattctacta ggtccttcta tcgtatttgg
    27481 tttgatttac ttcaacaatc gtaaattgat gagaactatg gatctgtaga ctttataaat
    27541 tgaaactttc aattaagaat gacagttttt atgtaaaaac tgtcattctt tttcattttt
    27601 tgaaacatat ggctaaacaa atgaaataaa acgtgctata cttttgaatg aaacaggttt
    27661 agaaactgta tcaattattt gtgattattt ctaactaata attaaaaata aagcataaaa
    27721 aggacgatgt tcaatggacg aaaaaatgaa acaaggttcg aaatctgtag tagaaagttt
    27781 gattaatcat catgttgatt atgtattcgg tataccaggt gcaaaaatcg atggtgtatt
    27841 taatgaatta gaggatcaag gtcctgaatt aatcgtgact cgtcacgaac aaaatgctgc
    27901 atttatggca caagcaatcg gacgtattac aggagagcca ggagtagtta tcgcaacaag
    27961 tggtcctggt gctagtaact tagctacagg tttggtaaca gcgacagcag aaggtgaccc
    28021 agttttagca attgccggac aagtaaaacg aagcgatcta ttgaagttga cccatcaaag
    28081 catggataat gcagcactgt tccagccaat cacaaaatac agtgcagaaa tccaagatcc
    28141 agaaacaatt tcagaagtga ttgccaatgc ttatcgtatg gctaagagtt caaaaaaagg
    28201 cgcgagcttt atcagtatcc cgcaagatgt agtggatgca cctgtccaag ggaatgtcat
    28261 caagccattg agcgatccta aattaggttc tgcttctgca gatgatatcc gttacctagc
    28321 tgaacgcatt agagaagcaa aactaccggt actattagta ggtatgcgag gatcaagtga
    28381 aaaagaaacg ttagccatca ggcaattagt tggaaagaca gcattgcctg ttgtagagac
    28441 attccaagca gctggagtga tctcacgtga attagaagcg catttctttg gtcgtgtggg
    28501 tttatttaga aaccaaccag gagatatgct tttgaaacga agtgatctag ttattgctat
    28561 tggctatgat ccaatcgaat atgaagcaag aaactggaat gcggaaaaag atgcgcggat
    28621 cattgtgatc gatgaagcgc cagctgaaat cgatcctttt atgcagcctg aaagagaatt
    28681 gatcggtgat atctcagcca ctcttgattt attgacaggt tcattagagc ctcaacaagt
    28741 gtcagaagat gcaaaagaat atttagcatc tcttcaagca gaattaacgg agcgggacat
    28801 tgttcaatca aaaggagaag caggtatctt gcatccttta gaagttatta acacgcttca
    28861 gtcaaaagta acagatgata tgactgttac cgtagatgta ggtagtcatt atatttggat
    28921 ggcacgccac tttagaagtt atgaacctcg tcatttgtta ttcagtaatg gtatgcaaac
    28981 gcttggtgtt gcattgccat gggcgatttc tgctgcattg gtgcgtccaa atacacaaat
    29041 cgtatcagtt tccggcgatg ggggattttt attctctgcc caggatttag aaacggcggt
    29101 acgtaaaaaa ttgaatatcg ttcatttgat ttggaatgat ggacactaca atatggtaga
    29161 gttccaagaa aaaatgaaat atcagcgggc gtcaggtgta gactttggtc cagttgattt
    29221 tgtgaaatat gcagaagctt ttggcgctaa aggaatccga gctacaagtg tagaggaatt
    29281 agaaaaagct ttagaagaag gatttgcgac agaaggaccc gtaattattg atattccgat
    29341 tgattaccgt gataatgaga aattgggaga aacaatctta ccagatcaat tctattaagg
    29401 aagtgtcgac atgactgaaa aaatcttata ccagcacggg acattaggag ctttgatggc
    29461 tggcttgatg gatggaacag aaacgattgc tcatatatta gaaaaaggaa ctctgggatt
    29521 gggaacattg catgggcttg atggtgaagt catcttttta gatggcgtag cttatcaagg
    29581 aagatcagat ggctcagttg cccaattaga tggaagtgaa cttaccccct atgcagcaat
    29641 tacagatttt acgccagata ctagtttttc tgtctcaaaa actgcagatg gagaacaatt
    29701 gaaaaaagac atattagtaa gagaagccgg ggaaaaccta tttttggcag tgaagataac
    29761 tggattattc aaaaatatgc acatccgtat catgccgaag caagaaaaac cttacagaag
    29821 actagcaaaa atttcagagt ctcaaccaga attccaacaa agcaatgtcc aaggaacatt
    29881 agtcgggttc tttacgcctg aattattcca aggagttgct gcagcgggat ttcacctgca
    29941 ttttatcgat gatacacata catttggcgg acatgtaatg gattttgaag tggctgaagg
    30001 aaaagttgag attagccgca tctcgtccct tgtacagcat tttccagttg atgatccgac
    30061 ttttgttcac gaaacgattg attatgctga tttagcagca gaaatccaac aagcagaata
    30121 gaaaaagaca gcgagatgcg ttcaaggtga ttaacctgac gtatctcgtt tttttgagga
    30181 gaaaacctag cgtttacaaa aaaactgagc tataatcttc tccatagatc aaaaaggagc
    30241 ggtttttatc atgtggacag aaaaacagaa aaaagatgca tacgaaattt tattattaca
    30301 gcaacaagga ttattagaag cagaagataa ctggttagca aatttagcaa attcatctgc
    30361 attgttgaat gagactttgc ctgagactgt ctttgcagga tattatttat tcgatggtaa
    30421 tgaattgatt ttaggaccgt tccaagggcg agtttcttgc acacgtatca agatgggaaa
    30481 aggagtttgt ggagaatcag ctgaaaaaca agaaacattg atcgttgatg atgtcaaaac
    30541 ccatgcaaat tacatttcct gcgattcagc cgcacaatca gaaatcgtag tgccaatggt
    30601 aaaagaaggt aatttaatcg gtgttttaga tatcgattgc ggagtaacga aagggtatga
    30661 tgaaatcgat caagcatttc tagaaaaata tgtagatctt ttattagcaa attttaatat
    30721 aaatgctttt tcatttatta ataactaaaa tcgtctattg aaacaaaaaa gaagagaaat
    30781 caagaataaa aagagccgga aagacagtgg gcatttctgt ttttcggttt ttttattttt
    30841 ttataaaatc acaagtgtta ttgattttca taatcatatt ttaatgttat tatcatttta
    30901 aataatgaaa aaacattaag gatggatgaa atatgaataa cgaaactatc attttaggaa
    30961 aaaaatatat ttgccaacct attggcttga aacaaaaagt gattggagaa gtaatcagta
    31021 aattagaaaa ttgtgttgtg atctgcgtag acgaatatca tgacgtcgat cgcaatgaaa
    31081 tattagaaaa atgcggaaaa gtagtggcaa aatatactca cgtttatgag ttggaaacaa
    31141 cagaatatct atataactat agcaacaaat atgaacatac tttagtttca taaagattta
    31201 aataaagtgc cttcaaaagc gagaagacca agcttttgaa ggcactttat ttagttggca
    31261 gtgattgttc atgatttttg atttattcaa aaggttcgcc tagagaatct gtctctgtaa
    31321 cgaggcctgg tggagaaact cgataaaaac ctatactgcc agaactgtcc tattttcgga
    31381 tagacaaact agtagtttta aaaagatcat ccgatccaat catttcaaaa aatgcaaaac
    31441 tgatatcagg atcatttagc tcaggcttgt tatcgtaaag catttgtaaa ggttgcattt
    31501 agttaggagt aaacgcgaaa ctatcatcat tatttgctga agaagatgaa gaagctaatt
    31561 cagagtttgt ttgaaataaa ggagacgtgc tgacagtttc tttaccctgt tttttgcaga
    31621 ggtagaaact tttatatcgg aagtttctac cggagaattt ttctcatttg tagaaattgt
    31681 tgaatcgata ctattcgaaa tttgcgtatc tgaaggtatg ttctttgatg cagaagtccc
    31741 acaagcagta agtaacaata aatttgataa actgataaac agaattcttt tcattatgta
    31801 cacactcctt atagtatcgt ttagcataca cctatgctca gtattaggca aaatcaatgc
    31861 aaaactatca agtcttttat agtatctatt agtcttagta atacatatat ggagagggtg
    31921 atatcccagt tcaaaccaga tacattggtt accatctgta ttaacgatta tgcctctaaa
    31981 cgcttttttt atgaaaaaat ttataagtga aaacgtaggt atgatattat ctagaggtaa
    32041 tttttttggg tatttaaata gttgctagga ggatagcttt tggattttta cagtaatttt
    32101 atcttaataa tagcaatatt attacttcta aatatttggt tttttgataa gagtagaaat
    32161 gcagggatag gttttagaac caaacgaagt acgtcttctg aaaaaaagtg ggtatattca
    32221 cagactattt tttacggagg ggttatttca atcagtttac tttcttcaac actttattct
    32281 tttaatgtta tagacgtttc catgtcaaat tttatatcta ttattggaat ccttatttct
    32341 gcaattatta cacaactact tcttgtgttt gaagagaagt caaaaaataa ttaaagcaat
    32401 tatgcctttt agtacaggaa ttattacttc ttacaaatgt atagcgaatg tgaagcctgc
    32461 tgttttaatt gttctagaaa aacttttgag tgaacaatta ttttatgtta ggatgaatta
    32521 atttctctag agtttata
//
LOCUS       DAFELK010000028        31484 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFELK010000028
VERSION     DAFELK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.029"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(47..493)
                     /locus_tag="LP433_001582"
     CDS             complement(47..493)
                     /locus_tag="LP433_001582"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBL2005751.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            complement(504..2717)
                     /locus_tag="LP433_001583"
     CDS             complement(504..2717)
                     /locus_tag="LP433_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBL2005752.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            complement(2950..3714)
                     /locus_tag="LP433_001584"
     CDS             complement(2950..3714)
                     /locus_tag="LP433_001584"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBL2005753.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            complement(3715..4662)
                     /gene="prmA"
                     /locus_tag="LP433_001585"
     CDS             complement(3715..4662)
                     /gene="prmA"
                     /locus_tag="LP433_001585"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBL2005754.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            complement(4675..5163)
                     /locus_tag="LP433_001586"
     CDS             complement(4675..5163)
                     /locus_tag="LP433_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBL2005755.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            complement(5129..5800)
                     /locus_tag="LP433_001587"
     CDS             complement(5129..5800)
                     /locus_tag="LP433_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBL2005756.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            5938..7224
                     /locus_tag="LP433_001588"
     CDS             5938..7224
                     /locus_tag="LP433_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBL2005757.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            7296..7490
                     /gene="ssrS"
                     /locus_tag="LP433_001589"
     ncRNA           7296..7490
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LP433_001589"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            7568..7852
                     /locus_tag="LP433_001590"
     CDS             7568..7852
                     /locus_tag="LP433_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005758.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            7925..8404
                     /locus_tag="LP433_001591"
     CDS             7925..8404
                     /locus_tag="LP433_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2005759.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            8627..8770
                     /locus_tag="LP433_001592"
     CDS             8627..8770
                     /locus_tag="LP433_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBL2005760.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            9348..10931
                     /locus_tag="LP433_001593"
     CDS             9348..10931
                     /locus_tag="LP433_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2005761.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(11368..12552)
                     /locus_tag="LP433_001594"
     CDS             complement(11368..12552)
                     /locus_tag="LP433_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBL2005762.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(12577..13584)
                     /locus_tag="LP433_001595"
     CDS             complement(12577..13584)
                     /locus_tag="LP433_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2005763.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(13756..14115)
                     /locus_tag="LP433_001596"
     CDS             complement(13756..14115)
                     /locus_tag="LP433_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005764.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(14087..14458)
                     /locus_tag="LP433_001597"
     CDS             complement(14087..14458)
                     /locus_tag="LP433_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBL2005765.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            complement(14475..14777)
                     /locus_tag="LP433_001598"
     CDS             complement(14475..14777)
                     /locus_tag="LP433_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005766.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            complement(14794..15264)
                     /locus_tag="LP433_001599"
     CDS             complement(14794..15264)
                     /locus_tag="LP433_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBL2005767.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(15239..15517)
                     /locus_tag="LP433_001600"
     CDS             complement(15239..15517)
                     /locus_tag="LP433_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBL2005768.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(15514..16563)
                     /locus_tag="LP433_001601"
     CDS             complement(15514..16563)
                     /locus_tag="LP433_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBL2005769.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(16520..17449)
                     /gene="tadA"
                     /locus_tag="LP433_001602"
     CDS             complement(16520..17449)
                     /gene="tadA"
                     /locus_tag="LP433_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBL2005770.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            17581..19335
                     /gene="ade"
                     /locus_tag="LP433_001603"
     CDS             17581..19335
                     /gene="ade"
                     /locus_tag="LP433_001603"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBL2005771.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(19433..20095)
                     /gene="trmB"
                     /locus_tag="LP433_001604"
     CDS             complement(19433..20095)
                     /gene="trmB"
                     /locus_tag="LP433_001604"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBL2005772.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(20165..20947)
                     /locus_tag="LP433_001605"
     CDS             complement(20165..20947)
                     /locus_tag="LP433_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBL2005773.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(21151..22362)
                     /locus_tag="LP433_001606"
     CDS             complement(21151..22362)
                     /locus_tag="LP433_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2005774.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(22355..23092)
                     /locus_tag="LP433_001607"
     CDS             complement(22355..23092)
                     /locus_tag="LP433_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005775.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            23230..23664
                     /locus_tag="LP433_001608"
     CDS             23230..23664
                     /locus_tag="LP433_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBL2005776.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            23657..24001
                     /locus_tag="LP433_001609"
     CDS             23657..24001
                     /locus_tag="LP433_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL2005777.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            24181..25191
                     /locus_tag="LP433_001610"
     CDS             24181..25191
                     /locus_tag="LP433_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2005778.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(25260..26204)
                     /locus_tag="LP433_001611"
     CDS             complement(25260..26204)
                     /locus_tag="LP433_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2005779.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(26188..28908)
                     /locus_tag="LP433_001612"
     CDS             complement(26188..28908)
                     /locus_tag="LP433_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2005780.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            complement(28905..30125)
                     /locus_tag="LP433_001613"
     CDS             complement(28905..30125)
                     /locus_tag="LP433_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBL2005781.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            complement(30406..31251)
                     /locus_tag="LP433_001614"
     CDS             complement(30406..31251)
                     /locus_tag="LP433_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2005782.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
BASE COUNT         9372 a         6465 c         5469 g        10178 t
ORIGIN      
        1 ttaagcgacg tgtttcatag tttttactag tgaaaaccag attactttat ttgtttttag
       61 aatcaataat gatcgttaca ggtccatcat tgacgagaga aaccgacata tctgctccga
      121 attgtccggt agcgactgtg atgccgcgac ttctgattcc ttcattgaat gattcgtata
      181 aaggaatagc tgtttctggt cgtgcggctt ccacaaagct tggtcgattt ccttttttcg
      241 tatccgcaaa cagtgtgaat tgagagatac ttaaaatttg tcctcccaca tcttctacac
      301 taatattcat ttttccttgt tcatcttcaa aaatacgcat ttgtgcaatt ttttttacca
      361 gatagtccac atctttttgc gtatcggttt catgaatgcc taataaaaca agtaggccgt
      421 agccaatttt tccaatttct tgctgatcga ctgacacagc agctttactt acccgttgaa
      481 caactgctct catatctgtc ctcctatcca ttcgtccggc gtacactgta gacatcaggt
      541 actgctttga ttttatccac gatactcttt aggtgggata aattctggat accaaccgtc
      601 aaatggatcg tcgccatttt atctttattc gtccgtgctt caacgctgtt gagatttttc
      661 gttagcgcat tgactgtttg aagtacatca ttcaataagc ctgaacgatt atagccgtaa
      721 atttccaaat ctgcatcata ctcttttcgt gtattcgatg tatcttccca ttcgacttca
      781 atcaaacgtt ctgctacatt tggtttgtca ggctgaacat tcggacaatc tcgacgatga
      841 atggatatcc ctctgccttt agtgatataa ccaacgatat catcaccagg aatcggatta
      901 cagcagcgac tgatacgaat tagtaagttt tctacccctt gaatgacaac gccaccttca
      961 tgacgtactt tcattttgtc aggttctttt ttcggctgat tcatgatttc ttctgcttct
     1021 tgcttttgct gctcgatttt ttgttcttta cgttcttttt cagtcagacg attggccatc
     1081 gtcaaggggc taacttctcc ataccctaca gctgcataga gatcatcttc tgtttgataa
     1141 ttaaaacgat cgagtgcttc ttgcagtttg ttcttcgtca aaatatcttt aggcgtaaat
     1201 cctagatctg taatacattt gaccacggat tcgtggcctt tgatcacatt ttcttctcga
     1261 tcttgggctt tgaagaaacg tttgatctta tttcttgctt tgctagtagc aactaatttc
     1321 aaccagtcgc gacttgggcc aaatgaattt ggagaagtca tgatctcaat gatatctccg
     1381 tttttcaatt tgtaatcaag ctgcaccatt ttgccattta cttttgcacc agtggttttg
     1441 ttaccgatat ctgtatggat actgtatgca aagtccaatg gtccggatcc ttttggtaac
     1501 tcagtaacgt ctccttttgg tgtgaagacg tagactttat cactaaagat atctcctttt
     1561 acgccttcca taaattcaga agcatcatag ctttcgtctt gaagttcgag tatctcatgg
     1621 aaccagctta attgtttcgt cataccatct ggttctactt tttcattttt tccttcttta
     1681 taggcccagt gtgcagcaac cccgaattca gcgatttcat gcatttcctg tgttcggatt
     1741 tgaatttcta ccggatttcc tgccggaccg atcacggtag tatgcaaaga ttggtacata
     1801 ttagcttttg gcatggcaat ataatcctta aatctgccgg gcattggttt ccattttgtg
     1861 tggattgctc ctaatacagc ataacaatcc ttgattgaat ctacgatcac tcgaatagct
     1921 agcaagtcat aaatttcgtt gaactgcttt ttctgatctt tcattttacg atagattgaa
     1981 taaatgtgtt ttggccgtcc atagatttct gcaaaaatcc ccagctcttc tgtcgctatt
     2041 cgaatatctt caacagtacc acttacgtat ttttcacgtt cttctctctt cgtctgcatc
     2101 aagtggacga tacggtaata ctgttttgga tttagataac gaagtgctgt atcttctaat
     2161 tcccatttga tccggctgat ccctagacga tgtgcaagag gcgcatagat ttctaaagtt
     2221 tcctgagcga tccttctttg cttatcttct cgcaggtgct tcaacgtacg catgttatgt
     2281 agtctatcag ctaatttgac catgataact cgtaaatctt gagccattgc tagcagcatc
     2341 tttcggtggt tttctgctag ctgctcttcg tgggatttat attttatttt ccctaatttg
     2401 gttacgccgt ccactaacat agcaacgtca tcgccaaatt cttctctcag atcttctaaa
     2461 gtgatttctg tatcttcaac aacatcatgt aagaagcctg tagccactgt atggggatcc
     2521 atttttaaat ctgctaatat acctgcgact tggataggat gaataatgta gggttcgcct
     2581 gattttctaa actgtccgtc atgtgcagca gtcgcgtatt cgcatgcttt ctcaacaaat
     2641 gctacatgtt cgggacccat gtattgacta acgagcttta tgacaccggg tcccgttaaa
     2701 atttcttctt ttgtcacagg aatcgatccc cctttctttt ttcggtaaaa cgggaatcgg
     2761 gacaaatatc tgtttgataa ttgtcccaaa atccgtgcag ttatacgttt ttttacggaa
     2821 atgttcgctt tttaaaagct ttttcaaacg atttttcgta tccattgtat aaataattgt
     2881 ttctattata caaattgttg actatttttt caattctttc tgtcgatact cttttattaa
     2941 tgaagaacgt tagctgaaag aaggattcat taattcccat tgatagctag cagcacttaa
     3001 taaataaaga ggtgctgttt ctgtacgaag gattcttggt cctaatccac aaagtatccc
     3061 tttgtgttct acaaaataat cgacttcatc gcgggataat ccaccttctg gtccaaagac
     3121 agctaagatt cgactatctg gttttgtttc actaagaatt ttggctgcat ttgatttttc
     3181 gccttgcttt gctgattcct cataagcaac caagaccacg tcataatcat ctagccgctc
     3241 aaataaatct tgtttcgttt ccaataactc tactgatggc acgatctgcc gatgggattg
     3301 ttccgctgcc tcttgagcaa tcttttcaag ccgttgttgt cgtttcatac gtttttttgc
     3361 atcccattta acgacagagg ctgatgccgg gaaaccaaga aaagcttgcg ctcctaattc
     3421 agtggatttc tgaacgatcc aatccagctt ttccccttta ggatagccac tcgctatggt
     3481 aatcgaactt ggcagttcct tttgattttc ttctttttta atttctttca gataaacagc
     3541 ctcttcagta atctccgtga tttctgcaac aatggctatt tgatcattga atgccaaaaa
     3601 aacttcatcc tcgggttcca tcctcataac ccgtacaatg tggtgatagt tttccccttc
     3661 taaaacaaaa tagtcttttg attcatatga ttcttttaaa aaataccgct gcatctattc
     3721 cacctctggt tttttcaaaa taattgcata ccagtctttt tgctggaaaa tttgatccac
     3781 gataaaccct tgttctaaca tggcatccag aaccatttgc ttcttctctt caatgattcc
     3841 tgaaacgatc agcgtgcctg tttgcttcag taaacgccaa gcatctggga tcatcaataa
     3901 gatgatatct gctaaaatgt tcgcaacgat tacatcactt tcaatctcga ttcctgtcaa
     3961 aagatcgtta gctgatacat ggacatcttt ggctatttca ttcatatcca tattttcttt
     4021 cgccgaacga acggctactt cgtctaaatc aaaggcatag acatcttttg caccaagata
     4081 ttttgctgca atacttagca cgcccgaccc agttcccaca tctagcaatg tttcaccacc
     4141 acgcaagact gtttctagtg ctgtcaatgt caaggaagtc gtgggatgag tgcctgtgcc
     4201 aaatgccata ccaggatcta gtgtgataat tttttctaga ggatcttctg tctggtagtt
     4261 ttcccagctt ggcgcaaccg tcagcattcg cgtaatacgc accggatgat agtatttctt
     4321 ccaggctgtt gcccagttgc tttcctctac ttcactaact gttactttat tttttccaat
     4381 agctagacca aactcaggta attgtgtgat acgatctttg ataaaaggca agatttccgg
     4441 taagaaagtc gtttccggaa aataagccat gactagtgcg ccttctttca gcgatgtaaa
     4501 atcattttta tctaaaatct caccatattg atccgactga aaatgttcaa catctaaaga
     4561 atcttcaatc gcgacaccac tcgcccctgc ctccatcaaa atattagcaa ctgcttcgac
     4621 tgcttcactt tcagtttcta cttttacttc attccatttc atatctgtca ctccttaata
     4681 acttgggtac ggtaaataag tatctgcttc attttgctgt tttacttcta ctaattctgc
     4741 tagttgctga ttatcccagt gaagctcgaa tacagcttcg tcatcgtctt catccaaaaa
     4801 atcaagcaaa tcgctttgcc cttgagctaa tacttcattt agatattcca ctaaagaatc
     4861 agctactgat tttgccaacc ctttttttcc ttcataaggg attactgcta gataattgcg
     4921 ttcatcaaaa acagatttct gaggattaaa aagaagtacg ccgtcttcaa attcgataat
     4981 tggttcttgc gaaacgatcc cttctgcatc atcaatctca aattgtgctt tattttctgc
     5041 aaacaagcga acaacgatct cgatcgtatg attttttgta tcccaatcta aagctacatc
     5101 atagtctgtc acttgttttt caattatttc atctaaatat gttaatagat ccttcttttt
     5161 cattttcttt cctccaaccc caatctttct cgatttggtt ttttctttgt aaagagatat
     5221 aaggatttcc cgacacaaca aaacgcaacg gcttttctgt ccatacacct ttgtttggga
     5281 taccgattct aggcaaagca ttgatctttt ttggtgtctt ttttttctca aaaactaagc
     5341 gtaacgaact atctgctata gactgaccat aaagttcttg aggaattgct aatgcttcca
     5401 ctaattttcc cggaccgttg ctgatatctg gaccagtttt tccgccacga tttttactca
     5461 tttgatcaat cattgcggcg ggttcgattg cacgtatcat tactccttga ggaatccctt
     5521 ctggctgagt aatgatgttc aaaatccgat gagtatgcat cgtgtaaagg tagatcgtac
     5581 ctggtttttc atacattgcc cgcacacgcg gtgttcttct taaaccatag ctatgggcgg
     5641 cctcgtcttc tggacctagg tatgcttccg cgtctacaat atatccagct aatcttcctt
     5701 ctggtgtgtc atgctccaaa tacatcccca ataaatcccg tgccacttct ggcgtcgttt
     5761 tattccaaaa aaattcatct atcttttgtt tatccgtcat ttttctcacc tactttatca
     5821 tacacaatat tagttggata agctatgaaa acaaaacaac agaaggctgt tctttctagg
     5881 catcttgcta aatatgatat aattaaggga cgtaaaaaca agaaggagga aaatcctatg
     5941 caacagccat tggcttatcg catgagacct cgaacgatcg atgaagtcgt tggtcagcag
     6001 catctagtcg gggaaggaaa aatcatacgc cgcatggtcg atgctcgcat gctctcttcc
     6061 atgattctat atggacctcc tggtactgga aaaacgagta tcgcaagtgc gatcgccggc
     6121 tctactaatt atgcatttcg catgctaaac gccgctacag attcaaaaaa ggatctacaa
     6181 gttgtagcgg aagaagcaaa aatgagtggt acagtgatcc tcttattgga tgaagtacac
     6241 cgattagata aaacaaaaca ggattttctg cttcctcatt tagaaagtgg ccgaatcatc
     6301 ttgatcggag cgactactga gaatccttat attaccatca atccagcgat ccgcagccgt
     6361 acacagatct ttgaagtcaa accattaaca gaacaagaca tccagttggc agtcgaacat
     6421 gctttaaggg ataaagaacg cggccttgga caacaagcaa tccagttaga cgaagatgct
     6481 cttcttcacc tttcgcgtgc aacgaacggc gatttgcgga gtgcattgaa tgggctggaa
     6541 ctggctacac tatcgactcc ttcagataaa gaaggaagga ttcatcttac actgtcgatc
     6601 attgaagaat gtgtccaaag aaaagctctt acccatgaca aaaatggaga tgctcattat
     6661 gacgttattt cggcttttca aaaatcgatt cgtggaagtg atgtggatgc tgcacttcat
     6721 tatctcgccc gtttagttga ggcaggtgat ctggcaagta tttgccggcg tctgatggtt
     6781 atcggttatg aagatatagg tttaggtaat cctgctgctg cggctcgtac agtgaacgct
     6841 gtattagctg ctgaaaaatt gggattgcct gaggcacgta tcccactagc agacgtcgtc
     6901 gtcgatcttt gcttgtcgcc aaaatccaat tctgcctaca tggcattaga tgcagcactt
     6961 gctgatattc gagagggcaa agctggagat gttcctgatc atttgagaga tagccattac
     7021 aaaggtgcga aatcactcaa ccgtggcgtg ggttatcagt atcctcatca ttttgatcag
     7081 gcttgggtca atcagcaata tttaccagat aaactgaaga atgctcagta ttatcagcca
     7141 aaagatacag ggaaatatga acaggctctg ggtcaacagt attaccgtat aaaagagtgg
     7201 aaaaagcatc ctccaaaaaa ctagacaaga aaacggttct gtttctgcga gctctctcat
     7261 tgctcttttt aaattcatat gctactatag aggtgggaaa tctgtgatgt tcgaattgtc
     7321 ctctttgtgt gttgaccgaa catttttatt gatatcttgg gacccgtctt gtgtcactgc
     7381 tggtaacatg ccttatcatt tggtagttcg aagctacgac catgggaccc acctgcttga
     7441 attcgcggga tcaatactac aggacaaaca acggcattaa cggagattac catcttttaa
     7501 agaataaagc aatttgctct tggcaaattg ctttttctat ttgttgctta ttttggagga
     7561 tttgttcatg attaggattt taatgattat cgccacttta gtattattat tcgttagcta
     7621 ttatttattt aataaacagg atatcttttt tgtattgatc aacaaaaatg ataaaaatca
     7681 aggattccta caattttacg gagctgcata tgctgtttta ggcgtaatgg gtattttaac
     7741 agcttttttc aatcaacgct ttattgcctt ggtcttttta ctgatcgtaa ttattgtttc
     7801 tgccaccttc agtatccgat ttgcaaaaaa aattgctgaa ccaaagcagt aaataattct
     7861 ctttttccct aaagtgttct acaataaaag agtacaatac gattgacttg aggagtgaat
     7921 gcttatgtta caacaataca aaaaaatcat ggttgccgta gatggttctg atgaagctga
     7981 attagctttt aaaaaggcgg tcaatgtagc tatccgaaat aacggagaac ttctattagc
     8041 acatgtcatt gacacacgtt ctttccaaac cgtttcatcc tttgatggaa tgcttgcaga
     8101 acaagctact gaaatggcaa agcaaacatt ggcagattat gaaagcaatg cgaagaaagc
     8161 tggcttgaat aatgtaacct ctgtcgtaga atatggctca ccaaaacaaa ttattgccag
     8221 agaaatccca gaagataatc aagtagattt gattatgtta ggagccacag gattgaatgc
     8281 tgtagaacgt ttatttattg gttctgtttc tgaatatgtt attagaaacg cagcttgcga
     8341 tgtgcttgtt gtccgaactg atttagaaaa ccaattgcca gctaaagacc acaccaaagc
     8401 ttaacacgta gacgacctgc caactatcgg caggtttttt tgcacaaaaa accgtgataa
     8461 aaacaaaaga cgcggcaagc actcatcggt ctttataatg tttaaaataa agggaaaaca
     8521 gtcaatgagt tcaagtaaaa taaaaaaaag tgaacaccag ggcgattagt cgccctggtg
     8581 tggtttaaaa cgacctaagc atgccaaagc ttattggttc gtcaatgtgg aagtttccga
     8641 tgaatctgat acgaaaaaat atgaagtatc gatggcggat accgatttta tcgccaaact
     8701 aaaattttat ttcgggttcg ggtaccgcga gaaggcaagt gctacattcg gtaaatcatt
     8761 caagaattga tgaaaggcta ccgcttgcca ttgcaaccac aacgatactc ctgaacgcga
     8821 tgttggtgag atttccaaag agaagagctg tttaatgcaa cggtattaag caaatggcaa
     8881 aaggaagtca tgtagacaaa gttttttatc aaacaccata tgatttcgcc tgaacgctgg
     8941 tttagctcag aatacaatga tgtggtccac gagacattac cctcagtcag ataaaaaaag
     9001 ctctctgaca gaattacaca tcgataaata ttaagtaaat gtcagcgcta gttgaacttt
     9061 ctgacacttt caggtacact ggaaaagaca actacacgaa ggagggaaaa tactatgatg
     9121 cgcatgacta aaataacaag taatgaaaat taccaacgat accatatcgc atttagccat
     9181 gcaattggtt ttacagttgc tgttgacggg acaagtttgt ccaaaacagt tgaattcacg
     9241 taaaatcaat ggccatctca aggtattttt ctcatgataa tctgagttta aataacacag
     9301 gccatggata accatggcct ttttgagtgg tctcaaggag agagatcatg atcatacaag
     9361 caatttctat taaaaaaaca atcggcggga atccattatt tgaggattta tcctgtcaaa
     9421 ttgaagctgg tgaaaaaatt gccttagtcg gtatcaacgg aactggcaaa tcaacctttt
     9481 tacaaatctt gaccggcaga gaaggtgtcg acagcggtgt tatcagtcgc aaaaaaggct
     9541 taaagatcgg gacggtcgaa caagaactta cagtttccga agcgaccgtc aaccactact
     9601 tgctccattc tgccgctgag atacaggacc tcaaacagca aatgagtcgc tacgaagcat
     9661 tgatgacaga accagataca aacttagaga agtgtctggc ccgttacggt gagctgcagc
     9721 atcgctttga agaactaggc ggttacgtat tagaagaccg gattgcagcg atcttgcaag
     9781 gcttagggat tccacaccgt caggaagcac ggttaacaga acttagcgga ggcgaacgag
     9841 ttaaagtcgc tttagccaaa attttagcag ccgatgccga tttactttta ctcgatgaac
     9901 cgaccaatca tttagatctt aacagtattc gctggttgga aaactattta cagaatacaa
     9961 aaaaatcggt tctggtcgtt tctcatgatc ggcaatttct cgatcaagtc accacaaaaa
    10021 catgggaact ggaagaaggt gcattgattg agtatcccgg aaactacagc cgttttcgag
    10081 tcttgaaaga agctcgcttg gctgagctga caaaaaatta cgaactgcag caaaaagaag
    10141 tccagcggtt gaaagtcatg attcgtcgtt ttcgtcagtg ggcacatgaa ggagacaatg
    10201 agtccttctt caaaaaagcc aaagaactgg aacgccgcct ggcgaaactg acactcgtca
    10261 aaccgccacc tcccccgaaa aatcggctgc aaagcttgtc taatggtgga aaatctggca
    10321 aagaagtttt catcattcaa aacttgcacc agcagtacgc tgatcaagta ctattcaaag
    10381 acagcagttt tgcagtctat cgtggagatc atttagccat catcggcgac aatggtgcag
    10441 gaaaatcaac cttactcaaa ttattactcg gtgaggaaaa gccttacggt ggcaccatca
    10501 aattaggtag tagcttgcaa atcggttatt tgccgcagca gctgcagttt gccgatcccg
    10561 atagccgttt gctggcttac gccatcacat tgactggaaa cgaagaagtc gctcgacggc
    10621 aattagccaa aagtggcttt tatcaaagcg atgtgggtaa acggatcaaa gatttatccg
    10681 gtggtgaaaa aatccgtttg gcgttgctga aactcttttt agaaaaaatc aacgtcctga
    10741 ttttggatga accaaccaat cacctcgaca gctatgctcg agaagaaatt gaagaaatgc
    10801 tgcaagacta tcaaggaacg ctcctagcag tcagccatga ccgctacttt ttgcagcaac
    10861 acttccaaga agcactcgtt attgatcagg agcagatcag ccgccagccg ctcggccaac
    10921 tgattgacta ggacgttttt tcgcaacaaa aaacttgatt ttcatacctg tgctttcacg
    10981 attcaggcaa agtacaggtg gaaaatcaag tttttattat tcgatcaatg aatgtttcgg
    11041 atcggttttc tagctaaaca taaagcgaag aataaagtcg acagcccacg aggctgatct
    11101 aaaaatgttt tttcttttta catatgtaat gtcccttata aagatgaatg aaaataaaat
    11161 attgggattt tcctgaaaat caataaataa aatgccagtc ttttcccttt tgaccacttt
    11221 tccaagcaaa attccctaag aagatcctgt aaaaaagaag ggaaattgaa gttaaattac
    11281 cattttgcgg tcttctccgc aaaaaaaaca catgcaagaa ttccctcttg catgcgtttc
    11341 atcttttatc ctaacgaatg ctttggctta gccgcgcaga cgctccacat cacgggcaat
    11401 cattagttcc tcatctgttg ggatcactaa tactcttact tttgattctt ttgtagagat
    11461 atctacttct tcaccacgca attcattcaa cgctggatcg atttcacaac caaaccaaga
    11521 catacctttg atgatttcac tacgtacatg tccgtcattc tcgccgatac cagcagtaaa
    11581 gacaattgca tcaacaccat tcatcgttgt cacataaccg ccgatgtatt ttcggatgcg
    11641 gtccacgaaa atgtcataag ctaaacgaat atgttctttt tcatagttct tttcaagatc
    11701 acgcatatca ctagacaatc ctgttaggcc tagcagacca gatttcttgt tcaaaacatt
    11761 gatcatttca tcaatatcaa tctctaattt ttccattaaa tatgggagaa cagctggatc
    11821 gatatcacct gaacgtgtac ccattgtcac cccagctaat ggtgtgaatc ccatagaagt
    11881 atccatggat ttacctccat cgactgctgt gatcgataca ccatttccta agtggcaagt
    11941 gatgattttt agttcttcga tcggtttgtt caataatttt gccgcacgtt ccgacacata
    12001 acgatgactt gtgccatgga agccatattt tcttactttg aaatcttcat aataagacac
    12061 cggtaagcta tataaataat tttgctttgg cattgttgag tggaaagatg tatcgaatac
    12121 agccacactc aaaatgtcag gtaaaatctt tttaaacgct ttgatcccca ttaagtttgc
    12181 aggattatgc aaaggagcaa attctgctaa ttcagcaatg cggtccatta ctttctcatc
    12241 gatcactact gaatccccat aagtttctcc tccgtgaaca acacggtgcc ctactccggt
    12301 gatttcatca taagagctta aaatttgcag ttcaatcaac tgatctaaca gcatttttac
    12361 tgctacttcg tggttttcga tatccatgat ttgttcgaat ttttgattat cgccgtactt
    12421 gatggtaaaa atagaatctt gtaaaccgat acgttcgacg atccctttcg caactacggt
    12481 ttcttctggc atttgatata attgccattt caaacttgaa ctcccagcat tgattgcaat
    12541 tgttttagac atatgactct ccttctcgtt gaatgattac agagcagatg atttccagtt
    12601 tttaaactcg ttgaaaaatt ccgtcacctt ctctggttct tttaatgaag caagtttcac
    12661 aagcaagact tcttttactt gttgtgcttg tggtcctttt ttctgtaaga tcaaaatact
    12721 tttttgcgat tgtttattac ggaacaattc atctggcaat tgaatcattc cttgaagata
    12781 accttcttct ttaaaccatt ttttgatttc ttcactttga tccgtttcta aaaatccact
    12841 cggcatcaaa aacaaaccaa aaccatccgg cttcacatat ttcattgatt gctctagcaa
    12901 taaatgatgt gcataactat ggccttcttc ggtacttgtt aaaaactctt ttgctttttc
    12961 gtcattcgga taataaccga ttggcaaatc gctgattgca aaatcgacag gatctattaa
    13021 taattcctgc aacccgtctt gatgaaagta ttgaacattt gcttgtgtca aatcacttgt
    13081 agaagctgcg acagccaaca atgtatcatc aatatccaca ccaattcctt ctgtttggta
    13141 ccccgcattc gataggttta aaagaactgt taataacaag ttgcccattc ctgccgcaat
    13201 atccagaatc ttaaccggtg cttttttatt tgtgtatagt tgttcaataa gaaaaacaaa
    13261 taaaaaaccg atactatcag gagtgagttg atggttcgcc tgcaaatgtt ctgtctggct
    13321 gcccttcaat aaaagtaatt gagacagtct gcgccattct tctggctcga aagaaagttt
    13381 cttcaactct tcataaagag ctgtgatccg ttgcgttgtc tcttttgtcg gcactccatc
    13441 caccacacgt acttgataat catctattaa attttctgca ttttcgacat aggcttctaa
    13501 aaaggaagtt cccaatgcat tctgtaaaag ctgaatagct tccaggtttt gattaaaccc
    13561 ttgttccatt ttttctggta acatggtgca cctcatttct agatatatta taacaatttt
    13621 ttcacctgtt taattctatc gaacaattga caaaatttca atcgttttca ctgtttttta
    13681 tttgtgaaac ggcaaacatt tttttattaa aaacagtgtt ataacagaaa agagggcgtt
    13741 ttcacgaaca ttccatcatt ctgtactagt atctgtatca ttttttactt cttctgtgaa
    13801 ccgaaagata aacggtgaga cttccacctc taagaatagg gactgttgta cccactgata
    13861 tgttacagat ccagttgtgt agtaaaaaac tccttccgaa ctttcggcaa gcgtagactg
    13921 ttccgataaa gccatctgct tcattatttt tgctatataa taatttttga ttcgtatatt
    13981 aagatccatt gacaaacggt agctttctaa tgctgccatc aataaaaacg tacataaaag
    14041 aaataaaagc aagacagaaa ataaaataga gcccttataa cattttctac tgatcgtttt
    14101 ttgtccatat ggcatatcca tcttctccat tttcaaagtg tacataaaaa gaaattgtgt
    14161 gttctttttc caataattga agctcagtga tacttgttaa cataggttga tgtccgccgg
    14221 aagttcttct tttacgtatc attgcctgat atctttcgat gatatactgt ttatcctcga
    14281 tcgtgtagtg cagttgctga tttttcacag agacattgtg actgctcttg agttcttctt
    14341 ctaattgtgc taaaaatatt agccactctt tttgatcttt acgctgcaaa aattcactta
    14401 cttggatggt ttgctgaatc aaaagattga atgtgagcaa tagactgctc aatatcatca
    14461 gtccaattag acattcaatc agcgtaaatg ctggaattac ttgttttttc aatactgatc
    14521 gcttctttct ccatattgac aaacactttt tcgattactc cattattatc gacaatttgg
    14581 atatcgtatg ggatcatttc ttcccttcgc tctggtcttt tgtgatacat ccgctgcgtc
    14641 ttgatatctt cataaatcat tcgaataaat agcagttcct ccccactttt cttttctgcc
    14701 tgaagcaaaa acagctggcc aaagctcact aagtagacac agacagaagc gatcataagc
    14761 gctgtaaggg actccaacaa aacaaatcct gttttattca attctttttg tatagcgacc
    14821 actccctatc tggaattgat acgtaatcgt ccgctctttt tcttcccaat aaaattgata
    14881 agcttttagt gaactttcat tcccggttct agcagcaaaa gtaatagaag catggcgttt
    14941 caaggtaatc tcatcaggaa tatctaatac ttcccaattt attttatctg gattcggaac
    15001 atgaaaaatg atttgattct cttcactatt ccaataaaag cctgtttgga tctgattcac
    15061 aatagcgatt ttttgcgtag aatagattcg tttttcaaat tggccgaaaa attgatagac
    15121 tgccaattca ttcttccatg cagaaaatgc gagaactgga aaagaaagga tcgttgtaag
    15181 taataaaatc agtaagagtg attcaaacaa cgtatatcct gatgctaaaa ccttaccttc
    15241 aaggccgctg atagatttct gcatgttctc gtttgatata gccttcattc aacaattcct
    15301 ccacagtagg aactcttcca ttattttgaa gcgcatagag ctctttttgt gtgtctacca
    15361 actggatgat cgcttcacga ctttcttggt ctacatgatt cctataacgc gacaaattag
    15421 ggacgaacaa caacactaat acactgatga tcagtaagac gattagcatt tcgatcaatg
    15481 taaaaccgct ataataagat atttttctct ttttcatggc aaaacctcct ctatgcttcc
    15541 gtaaacaggt aataaaacag cggcataaac taataaaatc aaagccgcta cgcccaaaaa
    15601 aatgattggc tgaataaaat gcatccagtg atgaagacgt ttgaaaagct gttttcttgt
    15661 ccattcgctg taaaaaatca gttctttacc taaacttccc tttgcctctc cctgtaaaac
    15721 aattttactg aattcttctg atagaaaacg ataattctgg aactgctcag ccaatgacat
    15781 acctgcctcc aatccttgaa tcaacttaga ggcaagatgc tgaatcagac tttcttgttt
    15841 cgtttccttt aagcagacta tgatttgcct taattcgaaa ccttcatgaa aaagctttcc
    15901 aatctctagt gacaaataag ccgattgata caaggaatat atcggtccaa tcaataattg
    15961 tctgcttatc cattcactct gatcaacagg agacaacttc atcagacgat accttactag
    16021 taaagccaat agagtaaccg ctaggatgaa tagtagaaca taccaatgaa agacttgtat
    16081 cagctgaata ccccaatgct cttgcatgac cattcctgaa ccaataagct gaggcaaaac
    16141 gaacaaccgc atactaaaca agatacctag caaaaaggtg agcaatagca tcggatatgc
    16201 aagcagcttt ttcaaatcat tgcgaaatcc ttcaacaagc cgaaactgtt tggcaatttc
    16261 caacaaagtt gtcggcagat tcccatgacg ttcagctaac tcgatctgta ccagttgctc
    16321 tgctccatat cctatttgcg aaagtacctc actaaacgct tgcccttcct ttagctgatg
    16381 ttggatattt gccaaaataa caggtggaaa cgaacggatc gtgagtaata aataaaggga
    16441 ttcttgcaga ctaaaaccag ataaaagcag ttctcccatg gtttgtgcaa actggttttg
    16501 ctggcttctt gttaatcctt tagaatagtt ctgactgcca aatattttcc tgagcttctt
    16561 cataactttc ctcccatgat ttttttactg attcttcctc cataaattga taactccata
    16621 aaacagaagg atggtgattg gcatcttcca aaagttcttg ataaatgaca ccagctaaac
    16681 attcagatag ctcttctttt ttctttgtca gttcatggat tctgaccaat gtaccttcaa
    16741 gattgcgtgc atgtacggtt gcaaaaaccc ggtgccctgt tagtgctgct cttaccgcag
    16801 catgtgcagt tgattcatct cttatctcgc caatgattag caagtctgga cgatgccgta
    16861 atgcgagtct caaaagtgta tcataagtct gtgctatttt cggattgatc tgtagctgca
    16921 gaaaaaacgg ttcttctatc tctacaggat cttcgatagt aatcacttgc aatttttctt
    16981 ccaaagccaa ccgatacatt agagaagtct tgcctgatcc gactggtccg ctgaaaaggt
    17041 ataatccacg tctgacggtt ttctgtaaaa tagttgcaaa atctcgagaa ctaaagcaac
    17101 gatggggtgt ttcaaaagta ccgtataata gccgaatcac taaactctct cgttgaaggt
    17161 aatctcctac agaagacaac cgcagacgaa cttcctgttt ttctaaagaa taagtaaatg
    17221 cacctaactg agcttttctt ttttctccga tatccatctg tcccaaatac ttaaatcttg
    17281 agatcagttg ctgtccatct gccgaagaga ctttcttcca gaatgttcgt ttttttccat
    17341 agcgaaaata gatgtaaaat acttctgaag ctggcaatat atatacgtct tgggcatgtt
    17401 tggcaaaact ttcacttatc atttgatccg ataatcgttt tatttccatt attctcccct
    17461 ccacaaaaaa catacgtctt tttgatcttt ttgtttcaaa taaaatgaat ttacaaaaaa
    17521 atattggcaa aaaccgaatt tatgttatac ttataaaaat ttatcttggg aggcactcca
    17581 ttggaaacaa cattaaggaa atatatcgaa gtagcaagta aaaaaaagcc tgctgaccta
    17641 gtgatcaagc atgctaagat cgtcaacgtc tttacgaaag aaatcatgga aaaagatgta
    17701 gcaatctgcg aaggaatgat cgtaggaatc ggtgaatacg aaggaaaaag cgtacataat
    17761 gctaatgggc aatatctagt gccaggattc atcgatggcc atgtgcatat cgaaagctca
    17821 cttttatcac caagcgaatt ttcaaaagta tccttgcttc atggagttac tactgtagtg
    17881 acagatcccc atgaaatagg aaacattgct gggagtacag gtcttgagtt tatgatagaa
    17941 gatgcaagac aaacactcat gaatatcttt tttatgctac cttcttgtgt acctgtaacc
    18001 ccttttgaga ccaatggtgc aaatttaaat gcaaaaaaat tagccccttt tttacaaaaa
    18061 cccgaagttt taggcttagc tgaagtcatg aactatcaag cagtagcaaa taatgaaaca
    18121 gacatcctag aaaagatcca attgatgcac cagcataaga aaaaaattga cgggcatgca
    18181 gctggtatcg gcatggaaga gttaaatgtt tatcctgcag caggtattcg gacggatcat
    18241 gaagctacaa ctgcaaaaga agctaaagaa cgtttggatc ttggtatgta tttaatggtt
    18301 cgagaaggga ccgttgcaaa agatctggca tcgctactac cggcgatcac acctgaaaat
    18361 tcaagaagat gcttctttgt caccgatgat aaactgatca atgatttagt aaaagaagga
    18421 tcaatcgatc atatcgtccg tcaagctatt gcacttggaa tcgatccatt acaagccatt
    18481 cagatggcaa cattgaatgc agcagaatgt tttgatttga aaacactagg tgcgattgcc
    18541 cctgggtatc aagctgattt cttcttaaca gacgatctta ccaagctgcc aattcatgaa
    18601 gttttctata agggaacatt agttgttcaa tctgggcaac tccaagacca tttatttgct
    18661 gatcattcaa attcatatac gtgttgtctg ccaaaactaa acgctcaacc attaaatcca
    18721 cattcgttag agctgcttct ttcttcttca caagcccatg tgatcgaaat tatcccgaat
    18781 agtctagtga ctaaagattt ggtagaaaaa gtggaccgac aaggcgaacg attcattcct
    18841 tcaatcgaaa aagaccaatt aaagattgcg gtgatcgagc gtcaccatca aacgggaaac
    18901 attggattag gcatagtgaa aggatttcag ctgaaacaag gagcgatagc gacaacgatt
    18961 gcccatgact cgcataatct agttgtcgtt gggacaaacg acgaggatat gctgtatgct
    19021 gctaatcttt tgattcaaaa aggtggcggg atgaccgttg tcaacaaaca gcaggaaata
    19081 gcttgtgttt ctcttcctat aggcggaatc atgacacagg aacctttttc gatcgtctat
    19141 gaacagttga atgaattaat aactaaagca catcaactag gagcagctaa aacctttgat
    19201 ccttttttga cactttcttt cttaacatta tctgtcatac ccgaattgaa gatcaccgac
    19261 aaaggattat tttcattttc tcgcttccaa ttgattccac cttgtggaaa aaccgatgaa
    19321 ataaatacat tttaaatcaa ataaatccca gaaaatacat tacatctgta atgttcattt
    19381 tctgggattt atttatggat attaatgttt ttatgaaagc agaaagttag tttcacagac
    19441 ttttcttttt ggtcttatct tgaaattgag cttctactcg ataaatacgt tgaccttttg
    19501 aagaaaattt ttcttcatac tccgtcataa tattgccttc aaattgactt tgatgtaaat
    19561 ctaaccatac ctgtttgagg atcatgccat attgagaaaa acttgccaga gaatactcaa
    19621 acaatccttg attatctgtt ttgaaatgga tttctccatt tggacgaaga atctgttcat
    19681 ctacagcaag aaaagtctta tatgtcaatc gccgtttttc atgacgtttt tttggccatg
    19741 gatcggaaaa attcagatag atttgatcta cttcgctgtc agcgaaatac tctgtcaacg
    19801 ctgatccatc cacatgtaga agtttcaggt taggaagcgg ttgttcgatc aacttgtcta
    19861 gtgcaatcga aacaacactg acctgcattt ctactccaat ataattgatt tcaggatggg
    19921 cttttgccat tccagtgatg aactggcctt tccccatacc aatctcaatg tggattggat
    19981 gatcgttttc aaacaattca ttccattttc ccttccacaa tgttggatca ctaattacaa
    20041 aattcgggtg agccgctaac atttccgctg ctcccggacg atttcggaca cgcattattt
    20101 atctccattc ctttcctcta attaaaaagg tctggccaaa tctccgcaga gtttgggcca
    20161 aacctcagcc actgaaaatt cgttttaatt gtaaaatttc ttcgttcatc cgtcgatgat
    20221 cttcacgttt gcaatatctg gtgatttctt ggagcaaatt catggccgca taccaatgaa
    20281 atttttcaag catttcgtca gtcgggcgta tgccataact gatcagccac tgattccagc
    20341 tagacagtgg cacataattt cctaaaatcg ttgcaatatc caccgcaggg tctgcaaaca
    20401 tgattgaatc ccaatcgact agatataaat aatttttaca tactaaccaa ttacgatggt
    20461 ttacatctcc gtgtactact gataagtttt ccttatctat tgacgggatc tgctcacgaa
    20521 gaaaacgatg gacaatttgc agaaattgat ttttctggag ttcttccggt aattcttttt
    20581 catatttttg cagcatcttc tccggcgtca tgacacgacc accgatacgg gtcagcatgg
    20641 ttttaagaga atttgaatga tgtaaatggt acaaaacatc aatcacgtcg tttctttgac
    20701 caatctcatt aggagtcagc aagcgacctt ccagccactc ttgtgctgtc aaagtatcgc
    20761 cattccccgt tcgttttgtc caaacaagtt ttggtgtaat tccttccctt gaaagagcag
    20821 ccaacatcgg agtcgtgttt cgtttaataa agactttgtc ctcatcacgc atgcctatgt
    20881 atgtttttcc tgtgtcgcct ttgatgggac gtaaccgcca ctcttggtct aactgaaact
    20941 ccatcatgca ttctcccgtc ctcttactct ttgttttgca gtacttatta ttctagtcgc
    21001 ctgaacacta cacgtcaagc acatatacgt tctttttcat ttaattgcca ttcaaaaaac
    21061 cagcttttct caaaaaaaat agaacgaaca gcattcttac tgtcaacgct ctatttttca
    21121 ttctcatttt taccctacac agctttgttt tcagtctgac atcttcttca aacgagttgg
    21181 tacatatagt ttaacaaaga gcatagtaac aatcaaataa gccgctagcg gaacccatcg
    21241 ctgctgccca tctaatacga ctgcagcaat caaaccaaaa ataaccgacg cgataattaa
    21301 tacccatgtg agtagatact gaatcgcctg cttcttctga ttcttatgga ttggataaag
    21361 ctgaacgaga accatatagc ggaactggtt cgctaaaggt aacagttgga aaccgatcaa
    21421 atataaaaat aagaaaccga taatcagact aaaataaaag tcgactactc cggcaatcaa
    21481 taacccacct ataattacta atcggaaata aagaccacta aaatcagaac ctcttgccaa
    21541 tcttcttgca aacaagtaaa gataagtgtt ttttgattct cttttaatat gagtcaatat
    21601 aggatccaaa tagcgtcttc ttttgatctt tgccgtaatt tcaggaacat ctgtgaataa
    21661 attgataaat tgatagatct gatgcaacct atgttcttct acatgcacca ttttctccca
    21721 atccaatcct ttttcttgtt gcttccacaa aaaccagtaa tatagacttg cctgtactaa
    21781 tgcacctgct attcctgccc atattagcca ataaaatgat agaaacaaaa agatcagaga
    21841 agaaaaaaac cagcctaatt tccaataacg aataacttgt tgatctagtc gaaacaattc
    21901 tgctctcttg atttgcagat gactgaattt caaactccat aatatgatca gatagacgaa
    21961 aaacatcgaa aaggattgct ccgtactaac caccactaat ggcatggcca atccgcatgc
    22021 caatatcaaa aagatcaacg gaaaaatgca agaatagcga aaagctcgtt ccaaataggt
    22081 ttgcatttct ttttctttag gaagtaaaaa aacaatatct gctgcctctg caaaagtagc
    22141 catcttaccc acgaataaac agagcatcca aaatacagag attatgagcc ctccaattgc
    22201 aaacggtggc tgcagggttt tcaaccaatt agaataatat aatcccacac cgccaatcaa
    22261 gaaaagacaa actaaaacaa aatgatcgtt caatacataa cgcatatatt tcatcatttt
    22321 cttttgatgt cttgctaaac gtttttgaaa aaaactactc atgtgcctgc tcctttgtta
    22381 aagcaatata gatttcgtcc aaagaagaat ccggcagctg aaattctttt ctcaacatct
    22441 caagagaacc gtctgctcgt atctctccgt tatgtaagac cacaaaacga tcacaatatt
    22501 tttctgcagt agctaaaata tgcgtagaca tcaaaatacc ggctccttct tttttcattt
    22561 ctaccatcaa ttcaagcaat gcattgatag ctagtggatc caagcctaaa aatggttcgt
    22621 cgatgatata taaagaaggc tcgatcaaaa aggcgcataa gatcatcact ttctgtttca
    22681 ttccctttga aaaattagct gggaaccagt caagacgatt agataaccga aaagtctcca
    22741 acaacttttc tgctcttttc attgctatat ccataggtat atcgtaggcc atcgcagtga
    22801 cttcgatatg ttctctcaat gtcaattctt catataaaga aggagtctct ggaatatacc
    22861 caatttgttt gcgatattct tccgtatttt tctttaagga tagatgattg atttctatcg
    22921 ttccttttga agcttccagc agaccgataa tgtgcttgat ggtcgtactt ttccctgctc
    22981 cgttcagtcc aatcaaccct actatctctc caggctgtac atcgaaactg atatctttta
    23041 acacagggag atgtccgtac ccccctgtga catgatcgat aattaaactc attctttttc
    23101 ctccgccatt tatttttatt tattatacca cgaagaaaat gacggtattt tgtttttttc
    23161 cttacaatag ctttaactta tggtaaagtt aagctgaagt atttattctt tatagaaagg
    23221 atgttttata tggaaaactg tattttttgc aaaatcatca atcaagaaat cccaagctat
    23281 aaaatatatg aagacgacaa ggtctatgct tttttagaca tctctcaagc aacgaaagga
    23341 cacacattag ttgtgcctaa acgtcatgta gcagatattt ttgaatatga tcccgaactt
    23401 gcaggagagg ttttttcgcg tgtgcctaag attgctcaag cattggaaaa agcttttcca
    23461 gaaatgaaag gtcttaatat cttgaataac aaccgtgaac tagcctatca atctgttttt
    23521 cattcacata tccatttagt ccctcgctac agcaaagagg atgatttttc tattcacttt
    23581 gtcaatcatc aagatagtta tggatcggaa gaactaaaag ctattcaaga aacaatcgta
    23641 aagcaggtgt cctgcgatga ttaaaaactt tttcaaagga ctgttatttg gagctgctgc
    23701 tggcactgtc ggaggtctgt tattggcgcc caggagcggg aatgaaacaa gaaagaaact
    23761 gatcgaagaa ttggaagaag caacaactct gacaaatgat ttaaataaca gcctgaatca
    23821 ttttaaaagc gcattgatcg aaacaaaaga aacagctgaa tctgtgattc ctgctttcca
    23881 agaagcaatc aaaaaagata tcgaagattt taaattccaa gccgaaccac gtatcacaca
    23941 aatcaatgaa caagtagaaa aactaaaagc tgatctgcca gagtatcctg aacaaatata
    24001 ataatgatta ttttctcaac agatttaact atataagtga gaaaagtttg cgtatttcct
    24061 aggaatgtga tgaaattttg aattttgttt gaaactacca cgacaacgtt tttaaaggaa
    24121 atgggatatg gtatagttaa tatataaaaa taataactaa ttacaggagt gcaaatttta
    24181 atgaaaaaaa aatcaattat tttggcagct actagtgcgt tggctgtttt aactctagca
    24241 gcttgttcag gcgatactaa taaagatatc gcaacgatga aaggcggaac gatcactgta
    24301 tctgatttct atgatgaagc aaaacttgaa tcatcgaacc aatccttagt acaacggatg
    24361 atcatttata aagtattcaa taacaaatat ggcgataaag taaccgataa gcaagtggat
    24421 gcagaatacg acaaacaagc gaaatcatta ggtgatactt ttgaatcaca attagaagct
    24481 gctggatata cgaaagatac ttataaagaa tatattcgta acaatttagc ttttgaagct
    24541 ggcttgaaag ctcacgtaga tattacagat gacgatttga aaactgcttg gaaatctttc
    24601 catccagaag tagaagcaca aatcatcaaa ttatcaagtg aagatgaagc aaaagatgtg
    24661 aaaaaatcag cggatgatgg agatgatttc tctaaattag ccaaagacaa atcaactgat
    24721 acagagacaa aagaagatgg cggtaaagtt aaattcgact caacgacaac aactattcct
    24781 gcagaagtaa aagaagcagc tttcaaattg aaagacggtg agatctccga tgttattact
    24841 acaacaaatc ctacttctta tgcgacagaa tactacgttg tcaaaatggt gaaaaaccaa
    24901 aataaaggca atgacatgga taaatacaaa gatcaactaa aagatatcgc tactgaaact
    24961 aaactaagtg acaatgcatt cacaactaaa gtaatcggtg aagaattaaa agatgcaaat
    25021 gtaaaaatca aagatgatgc ctttgaaaat gtgttgagtg cattcacaac aacttcatca
    25081 agtacgaaag actcaagtga aactacagct tcaacaaaga gttctgacac aaaatcaact
    25141 gattcaacaa aagaatcttc aactgaagaa acaactgatt catcaaaata aaagaaaaca
    25201 aaaaaagcga agacttatgt ctcgcttttt ttgttttgaa tgaaaaaaat aaatttttgc
    25261 tataaatctt ttggtacata gaaacttcgg ttgtccatac cgaaaatccg atcggtgtat
    25321 tttcctggtt ctgtttgacg aatcgaagtc aacatcatct gcatcgaagc atcgatattg
    25381 tcgatttgat gtaatatttc tgcttccatt attcttggac gtacaggtga gccatattct
    25441 aataagccat ggtgtgctaa aaccatatga cgtaatacga gaacatcttc gtcagcttcg
    25501 ctgattttca acgcaagaca ggctttagtt atttcttcgt caatcaatac cagatgaccg
    25561 atcaaatttc ctgcaagcgt atattctgtc gacataggac cggaaagttc aatcaccttt
    25621 cctaaatcat gcaaaatgat accagcatac aacaatgctc gattcagctc aggatattca
    25681 tcggcgattg atttccctaa gtgaagcatt gtcaaagtat gataagctaa tccactggca
    25741 aatgcatgat ggtttctttt tgctgccgga aactcaaaaa attgtttttg atatttatta
    25801 agtagatagc gaacaatacg attccaatgc gcattggtga tctcaaacaa caattgattg
    25861 atttcttctt ccatttcttc tttcttcaaa ggggctcttt ccatgtataa actaggctct
    25921 cctggctcat ctacccttgt taagcgcata tgaagaatct ttacttgagg gtttccttga
    25981 taaacctctc ttttaccgtt tagaaaaacg actgtgccgg ctgtaaattt attgatttcc
    26041 tcctccgaag catcccagta tttaccatcg atagtacctg aagtatcttg gaaagtaaaa
    26101 gcaataaatt tttttccgtt tttagcgatt cttacatctg cacttttgat caggacaaat
    26161 tgttcaaact gctcatcgat tactaaatca cgaatttttt tcattatttg ctccttctaa
    26221 ttgttttacg atttggttca tctcatggta atagcttacc atttctttat cagaagaaaa
    26281 acaaattatt tgatactttt ctccaaattt agctaaaagt tcagctaatt gatactttcg
    26341 ctgatgatca taatgaagcc agccatcatc aatgatgatc gggcatatcg aacggttagc
    26401 ttctaatgag aggtaagcaa atctcatcgc cataatcagc tgatctttcg tacctgtaga
    26461 taactcatag atgggaaatt ctgtatatcc gtctgttaaa gtcagtgtat catttttcag
    26521 taatatcttc tgataatttc cttttgttaa aatacctaaa taatcacctg ctgctcttaa
    26581 caactggggt aattgtcttt cactcatctc tgttgaaaga tcacctaaga atgtcccggc
    26641 gatttcaagt gctccccatt cctccagtaa ttcctgtaat tttgcttttt gccggctagc
    26701 ttgttgataa agttcgtcca atgtgccgtc tctttgcaac tcttctactt gaagttggag
    26761 tcgttgccga ttttcacttg cttctttttc ttcttgctgg agttgggatt gcttttcttt
    26821 cagttggcgc agtcttacag ataatttctc ttttgtcagc tcttcaggaa atagtggagt
    26881 aagcatttcc gataattcat tgtatctttt catctgctgt tcggcttgtt tggctttttg
    26941 taaaaagaca ggtacttccg aaggataaga taagcctgct tgagtcaatt gttcgctgta
    27001 ttcttgtatc catacttttt gtttcttttt caattgattg atttcttgct tcaataaagt
    27061 attttgctga tagcttctgg caaatttcat ctgttccatc tcttgtataa aacgggaaag
    27121 caataccatt ttttctgaaa ttgtcttatc ttgtatcggt aaccattctt taacaaactc
    27181 aaatttttgg tcgatttgtc gtagtttttc ttgtatttcc tgttctcttt tatgtttccg
    27241 ctcaaatacg ccatataatt tctgataatc tatgacttcc tgtccatatt ctttcatgag
    27301 tttgagcgta tccatctttc ctaagtgccg atgatccgca aaacgatata cttcttgctg
    27361 aagaatctgt ttttcttctc cagttctctt ttgtttttct tctgcttcag ctaattgagc
    27421 taaggctaga tcaagttgtc ctagtttttc ttgccacatt ccttttatct cagagaaatc
    27481 atttttagtt ttaatttttg gttgcctttt gtagaagaaa tagccaatca tgcctgcacc
    27541 aattagtaaa aggatcactt tcaagggcat tggtacaaat atacctgcaa tgattattgc
    27601 tccgccagcc atcagcatat acggtttaga tgaagagact ggtgctatct ctgactgatt
    27661 ttgtaataat gctggatagg tctcttccaa gtcattcact tctgcttcaa tcatctcttg
    27721 ctgttcttta gctatttgga gacgcacaga aatctggctt tctagatcag caatccttct
    27781 ttcttcagcc agaagatgct tccattcttc ttcatataaa aattcttccg gtaacggatt
    27841 tttctgccaa tgccaccttt gttccaaaat cttcaattct gaatttgttt ctctagtctc
    27901 aatttgtaat ctttgccatt cttcgtttaa ttgttccgct gtaaattgaa gttgctggag
    27961 atcttttagt tcctgctcct gctctaaata aaaataatat ctggctgact gctgatccat
    28021 cccgctatgc ttttccagtg ttgcttctaa ttcttccaaa cgctcatttg tttgctgata
    28081 ccgtttggag aaagactcca gatctaaaag aagttgctca tcaggaagac ctgtagtgct
    28141 gttttttttg agagattgcc attcttcata taaagaaaaa ttaagttctt gctgtctggc
    28201 taatgaaaat tgtttgttcg cctcttttaa ttgtgccaat aactgctgct gttgcgactc
    28261 gtattcctgt tcttgttgga tcaacttgcc aaaataagct tcctgttctt gtttttgatg
    28321 aattttttct tgcagctctt tccattcatt taatttttga ttgattagta atttttggcc
    28381 ttttttcttg aataattgtt gtgctttctg ataatattct tgccgctttt ggaatacttg
    28441 agaactgccc gtgatgccta aagaaatcag cgcatcatgt agctcttttt ctctcaaatg
    28501 atctagttcc atcaactgct cttgctggaa agtaaatacc tgctggaata actctttcgt
    28561 caaaggtgcg atcagttttt ctagtaactc atcacttccc acttgatccc ccagccacac
    28621 cttcgatttt ccgcgatttt gctgcttgta gcgctcgaca gcaaattcac catatacagg
    28681 atgtttaagc catattttgc cgccataggc tgagccgtct tttggtgtat aatccttttt
    28741 tttacggcct tttgaaggga aaccaaataa tattgcttga ataaattgat aaatcgttga
    28801 ttttcctgct tcgtttcccc catagatcag ctgattgcct gaataaaagt caaaactttt
    28861 ttgacgccat tttccaaaag cagcaatctc gatccttaaa atcttcattc ctgatcctcc
    28921 tcaaataaaa aatcttgatt aagcagctgc ttggcttttt caagtgtttc ttcttgatat
    28981 tccggcagtt cgctcaatat tctagccgct tcttgatgac tatatacttc atttaaaatt
    29041 tgttggaaat cttgaggtgt ctgatagtat tgaaataact gttccatcaa tttagcagaa
    29101 gcagcaagtg gggtcttcgt ataaaaagta ttctctatga gagaaatacg ccaaataaag
    29161 aaatcattta tcctatctga gaattcctct aacaaatagt ctaatagctc tcctgattgt
    29221 atccgttcca aaacatctgt attgagatgg tcataatctt ttaattttat ctcaattaaa
    29281 ctaaatccat cctctacttt tgaaagctgc tgacgaatgt gaacaatgac ctcttttgtc
    29341 gttcttgctt tcctcaatga tatttccttt gtcttccaat agacctctgc tactttaatc
    29401 ggatgtattt ggcaacttcc tttacttaat tcaactagta gaatagatgt agaagcttgt
    29461 tcctttttag tatgaccttg aggcgcacct ggataaacaa ttgtttgctt ttcatttaag
    29521 accgttggca catggatatg ccctaaagcc caataatcgt atcccttttc ttgcatcttt
    29581 gagggttgga aaggagcata gtttcctttt tgagagacgc caggttcccc gtggtacaac
    29641 ccaatatggt aatctgtgag ttctctagaa ggaaattcca tcactttgtc tttttgaatc
    29701 cacggttgac gataactaaa tccactgaga gagacagttt ctccactttt tatcgttatt
    29761 ttttttgtct ctaccgtttc ggatgtaaat aaatggacat ttttaggaaa ggagaaccaa
    29821 taccgctctt tttgatagaa atcatgattt ccgaatatta taaatacagg tatatggttc
    29881 ttttctaacc gtttcatctg ttctgaaaaa tgtttctgta tttttaatga aggacgattt
    29941 tgatgaaaat tatctcctgc aagtaaaaca aaatcaacgt tatttattat tgcctgttca
    30001 atgatatttg ataaaacggt cagattcgtc ttcaatagtt tttcctgtac agttttatca
    30061 agagttgtca gtccttcaaa tgaccgatcc atatgtaaat ctgccgcatg gataaatttc
    30121 accattaaaa atttcctcct ttttttcttt tatcatacca ttttcaatgt tttttttcat
    30181 caataaccga aaatttgttc gtattatgca aagaaattac gataaatggc cgacttcaaa
    30241 aaataagttt attcgaaaaa aagattgtga catgattttt gtcacaatcc taaatatcta
    30301 tgttatattc gcttcgtttg acactgaaga agtactattt gtactggaat ttatgctcca
    30361 tttttccgta tttagaattc tatgttctat actaccttaa ttagtttata tggtaagaat
    30421 tctttcaaat gcttgagata ctccgtcttt atcatttgaa acagtgacat aatcagcttt
    30481 tttcatgatt tcttgatgac tatttcccat tgcaaaacta atatctgcac tttcaaacat
    30541 agataagtca tttaaactat ctccgatcgc gattctcaaa ggtttcttta aattgtagat
    30601 tgattccaaa cgatcaaaca ccacaccttt agatacattt tgaggtacga tttcaatatt
    30661 tacaggtgcc gattcagtaa cagacacatt tagcatcttt ttcaaatggt taaatatatt
    30721 agctttcaat tgacgattag gaataaaaat aaaaaatttg taaatgctga tagcatcctt
    30781 ttctataatt tcctcaatat tattataagg gattgaacaa atagattttt catactcaag
    30841 ctcatagttt agctctttga tagaaaattc actccctacc tcgtgaaaaa tttttttcat
    30901 tttattttta taattctgag attcataact tccgagattt gtatatattt tggttggaaa
    30961 tttcgatagg acagaatcaa ttttttttac atcattttta tcgaaggaag actcaaatat
    31021 ctttttttct ccatcaaatc caacagaacc atttaaccct actgctggta tccttaaacc
    31081 agattttttg agaatattat taatgtcttc tacttctctt ccagaacaaa tgaatggaaa
    31141 acagtcttcc ggtaaatgtt tcattgttct tgcatttttt tgactaatgc tctggtcaga
    31201 attcaaaaga gtaccgtcta aatctatacc aattagtttc atttcatcca tgtctcctat
    31261 acgttgatta taaattcact gcttattgta agtctaaatt tctcacaaaa catatactaa
    31321 ttatacctaa tttaagtaag tacaaacatc attttaagaa taggaaagga catttatata
    31381 ctattctctg tatttttgat ttataaataa atatgaattg aatccaaatc agctatatta
    31441 ctattttata ataaccaact ataaaaaacg aagttaggtg aaaa
//
LOCUS       DAFELK010000029        31063 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFELK010000029
VERSION     DAFELK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.030"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(61..2424)
                     /locus_tag="LP433_001615"
     CDS             complement(61..2424)
                     /locus_tag="LP433_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HBL2005783.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2872..3093
                     /locus_tag="LP433_001616"
     CDS             2872..3093
                     /locus_tag="LP433_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2005784.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="LP433_001617"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="LP433_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBL2005785.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="LP433_001618"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="LP433_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBL2005786.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="LP433_001619"
     CDS             complement(5894..6205)
                     /locus_tag="LP433_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBL2005787.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="LP433_001620"
     CDS             complement(6202..6495)
                     /locus_tag="LP433_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBL2005788.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="LP433_001621"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="LP433_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBL2005789.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="LP433_001622"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="LP433_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBL2005790.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="LP433_001623"
     CDS             complement(8333..12685)
                     /locus_tag="LP433_001623"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBL2005791.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="LP433_001624"
     CDS             complement(12897..14606)
                     /locus_tag="LP433_001624"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBL2005792.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="LP433_001625"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="LP433_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBL2005793.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="LP433_001626"
     CDS             complement(16103..16903)
                     /locus_tag="LP433_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBL2005794.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="LP433_001627"
     CDS             complement(16900..17712)
                     /locus_tag="LP433_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBL2005795.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="LP433_001628"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="LP433_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBL2005796.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /locus_tag="LP433_001629"
     CDS             complement(18467..19189)
                     /locus_tag="LP433_001629"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBL2005797.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /locus_tag="LP433_001630"
     CDS             complement(19325..20206)
                     /locus_tag="LP433_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBL2005798.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="LP433_001631"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="LP433_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBL2005799.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="LP433_001632"
     CDS             21446..21925
                     /locus_tag="LP433_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBL2005800.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="LP433_001633"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="LP433_001633"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBL2005801.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /locus_tag="LP433_001634"
     CDS             23226..24011
                     /locus_tag="LP433_001634"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL2005802.1"
                     /translation="MIKTVIYDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /locus_tag="LP433_001635"
     CDS             complement(24357..26048)
                     /locus_tag="LP433_001635"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBL2005803.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="LP433_001636"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="LP433_001636"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL2005804.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="LP433_001637"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="LP433_001637"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBL2005805.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="LP433_001638"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="LP433_001638"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBL2005806.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="LP433_001639"
     CDS             30332..31033
                     /locus_tag="LP433_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2005807.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT         8391 a         6625 c         5503 g        10544 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttatgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg ata
//
LOCUS       DAFELK010000030        29948 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFELK010000030
VERSION     DAFELK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.031"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(26..328)
                     /locus_tag="LP433_001640"
     CDS             complement(26..328)
                     /locus_tag="LP433_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2005808.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="LP433_001641"
     CDS             complement(353..2446)
                     /locus_tag="LP433_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2005809.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="LP433_001642"
     CDS             complement(2935..3699)
                     /locus_tag="LP433_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBL2005810.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="LP433_001643"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="LP433_001643"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBL2005811.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="LP433_001644"
     CDS             complement(4704..5780)
                     /locus_tag="LP433_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBL2005812.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="LP433_001645"
     CDS             complement(5804..6397)
                     /locus_tag="LP433_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBL2005813.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="LP433_001646"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="LP433_001646"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBL2005814.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="LP433_001647"
     CDS             complement(8067..8366)
                     /locus_tag="LP433_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBL2005815.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="LP433_001648"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="LP433_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HBL2005816.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="LP433_001649"
     CDS             complement(10121..11032)
                     /locus_tag="LP433_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL2005817.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLEKLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="LP433_001650"
     CDS             11152..12009
                     /locus_tag="LP433_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2005818.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="LP433_001651"
     CDS             complement(12196..12558)
                     /locus_tag="LP433_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBL2005819.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            12904..14343
                     /locus_tag="LP433_001652"
     CDS             12904..14343
                     /locus_tag="LP433_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005820.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14350..16902)
                     /locus_tag="LP433_001653"
     CDS             complement(14350..16902)
                     /locus_tag="LP433_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBL2005821.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17016..18347)
                     /locus_tag="LP433_001654"
     CDS             complement(17016..18347)
                     /locus_tag="LP433_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2005822.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18313..19791)
                     /locus_tag="LP433_001655"
     CDS             complement(18313..19791)
                     /locus_tag="LP433_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2005823.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="LP433_001656"
     CDS             complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="LP433_001656"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL2005824.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22401..23828
                     /locus_tag="LP433_001657"
     CDS             22401..23828
                     /locus_tag="LP433_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005825.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23920..24285)
                     /locus_tag="LP433_001658"
     CDS             complement(23920..24285)
                     /locus_tag="LP433_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL2005826.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24282..24647)
                     /locus_tag="LP433_001659"
     CDS             complement(24282..24647)
                     /locus_tag="LP433_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL2005827.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24839..25087)
                     /locus_tag="LP433_001660"
     CDS             complement(24839..25087)
                     /locus_tag="LP433_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005828.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25086..25214
                     /locus_tag="LP433_001661"
     CDS             25086..25214
                     /locus_tag="LP433_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBL2005829.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25271..26965
                     /locus_tag="LP433_001662"
     CDS             25271..26965
                     /locus_tag="LP433_001662"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBL2005830.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            26969..27088
                     /locus_tag="LP433_001663"
                     /pseudo
     CDS             26969..27088
                     /locus_tag="LP433_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            27616..28749
                     /locus_tag="LP433_001664"
     CDS             27616..28749
                     /locus_tag="LP433_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBL2005831.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28780..29100
                     /locus_tag="LP433_001665"
     CDS             28780..29100
                     /locus_tag="LP433_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBL2005832.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29129..29593)
                     /locus_tag="LP433_001666"
     CDS             complement(29129..29593)
                     /locus_tag="LP433_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2005833.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29725..>29948)
                     /locus_tag="LP433_001667"
     CDS             complement(29725..>29948)
                     /locus_tag="LP433_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2005834.1"
                     /translation="VSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAA
                     VNLVLSILIYLPFVKVATIQERRKEALDA"
BASE COUNT         9032 a         6212 c         5169 g         9535 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 gtttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
    14341 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
    14401 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
    14461 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
    14521 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
    14581 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
    14641 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
    14701 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
    14761 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
    14821 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
    14881 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
    14941 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
    15001 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
    15061 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
    15121 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    15181 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
    15241 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
    15301 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
    15361 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
    15421 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
    15481 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
    15541 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
    15601 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
    15661 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
    15721 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
    15781 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
    15841 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
    15901 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    15961 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
    16021 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
    16081 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
    16141 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
    16201 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
    16261 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    16321 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
    16381 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
    16441 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
    16501 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
    16561 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
    16621 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
    16681 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    16741 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
    16801 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
    16861 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    16921 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    16981 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
    17041 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    17101 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    17161 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    17221 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    17281 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
    17341 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    17401 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    17461 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
    17521 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    17581 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
    17641 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
    17701 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
    17761 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
    17821 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    17881 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    17941 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    18001 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    18061 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    18121 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
    18181 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    18241 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    18301 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    18361 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    18421 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    18481 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    18541 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    18601 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    18661 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    18721 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    18781 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    18841 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    18901 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    18961 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    19021 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    19081 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
    19141 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    19201 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    19261 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    19321 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    19381 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    19441 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
    19501 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    19561 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
    19621 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    19681 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    19741 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    19801 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    19861 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    19921 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    19981 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    20041 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    20101 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
    20161 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    20221 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    20281 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    20341 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    20401 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    20461 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    20521 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    20581 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    20641 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    20701 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    20761 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    20821 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    20881 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    20941 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    21001 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    21061 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
    21121 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    21181 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    21241 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    21301 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    21361 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
    21421 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
    21481 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    21541 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    21601 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    21661 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    21721 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    21781 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    21841 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    21901 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    21961 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    22021 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
    22081 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
    22141 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
    22201 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
    22261 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
    22321 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
    22381 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
    22441 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
    22501 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
    22561 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
    22621 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
    22681 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
    22741 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
    22801 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
    22861 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
    22921 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
    22981 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
    23041 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
    23101 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
    23161 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
    23221 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
    23281 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
    23341 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
    23401 tttatctttt aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
    23461 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
    23521 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
    23581 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
    23641 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
    23701 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
    23761 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
    23821 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
    23881 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
    23941 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
    24001 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
    24061 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
    24121 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
    24181 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
    24241 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
    24301 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
    24361 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
    24421 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
    24481 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
    24541 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
    24601 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
    24661 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
    24721 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
    24781 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
    24841 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
    24901 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    24961 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    25021 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    25081 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    25141 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    25201 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
    25261 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
    25321 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    25381 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    25441 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    25501 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    25561 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    25621 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    25681 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    25741 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    25801 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    25861 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    25921 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    25981 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    26041 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
    26101 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    26161 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    26221 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    26281 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    26341 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    26401 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctattgt
    26461 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
    26521 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    26581 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
    26641 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
    26701 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
    26761 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    26821 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    26881 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    26941 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
    27001 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    27061 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaagctg ccctgcatca
    27121 agtaataaga gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt
    27181 accgcagatg caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt
    27241 tcgagtatga agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt
    27301 aataccgaga aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt
    27361 gaaaacaact attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac
    27421 aactatttca atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa
    27481 tacataagac tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa
    27541 gatctccttt aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg
    27601 aaaggagcat ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga
    27661 aacgtagatg atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca
    27721 gccatttgcg gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg
    27781 tatgttgtag gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca
    27841 ttgaaaaaag ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc
    27901 tgcctgaatc acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg
    27961 cttttcggat ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga
    28021 gttccttatg cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa
    28081 gttttatttc tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta
    28141 aaaaaaggcg atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa
    28201 ttcgctgtta tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta
    28261 gataaagcgg ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct
    28321 ggaacagaat tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga
    28381 atggacggat tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc
    28441 acaatctctc cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta
    28501 actggtgttt atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat
    28561 atcgctgtca agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg
    28621 attgcagaag gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa
    28681 gcagcacaag catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg
    28741 aaaccttgaa ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat
    28801 acccatgaga tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc
    28861 ttctatttcc aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt
    28921 ttctatattt ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat
    28981 ttttatttgg ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac
    29041 atttttattt acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga
    29101 gaatttttca aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag
    29161 cggtcgtccc actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa
    29221 acgtggtatg atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc
    29281 tgatttccgc taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca
    29341 gggcacaaag atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg
    29401 ctcctccgac gatggtttct ttttcatcta agaccacata ccattgagga atactttcct
    29461 tattagcgat tccagtacga atactttcct catacacaac agcaggaact ccccattttg
    29521 atgaaaacca attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt
    29581 tatatgtaac caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag
    29641 tctttatgaa aattagcaat gacaacaata gtgatgtaaa aaaaaaaacg gaaaacaatc
    29701 acttgttctc cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat
    29761 cgtagctacc ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc
    29821 tagtacacca cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac
    29881 ccatggaggc ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac
    29941 actaacta
//
LOCUS       DAFELK010000031        29361 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFELK010000031
VERSION     DAFELK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.032"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(625..987)
                     /locus_tag="LP433_001668"
     CDS             complement(625..987)
                     /locus_tag="LP433_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005835.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(1061..1441)
                     /locus_tag="LP433_001669"
     CDS             complement(1061..1441)
                     /locus_tag="LP433_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBL2005836.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1505..2698
                     /locus_tag="LP433_001670"
     CDS             1505..2698
                     /locus_tag="LP433_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2005837.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2775..3359)
                     /locus_tag="LP433_001671"
     CDS             complement(2775..3359)
                     /locus_tag="LP433_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2005838.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3560..4558
                     /locus_tag="LP433_001672"
     CDS             3560..4558
                     /locus_tag="LP433_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2005839.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4670..5179
                     /locus_tag="LP433_001673"
     CDS             4670..5179
                     /locus_tag="LP433_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBL2005840.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5209..5868)
                     /locus_tag="LP433_001674"
     CDS             complement(5209..5868)
                     /locus_tag="LP433_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBL2005841.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5870..6634)
                     /locus_tag="LP433_001675"
     CDS             complement(5870..6634)
                     /locus_tag="LP433_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBL2005842.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6642..7319)
                     /locus_tag="LP433_001676"
     CDS             complement(6642..7319)
                     /locus_tag="LP433_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBL2005843.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7356..8741)
                     /locus_tag="LP433_001677"
     CDS             complement(7356..8741)
                     /locus_tag="LP433_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL2005844.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8951..9035)
                     /gene="ffs"
                     /locus_tag="LP433_001678"
     ncRNA           complement(8951..9035)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LP433_001678"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(9058..9573)
                     /gene="tadA"
                     /locus_tag="LP433_001679"
     CDS             complement(9058..9573)
                     /gene="tadA"
                     /locus_tag="LP433_001679"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBL2005845.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9680..10537
                     /locus_tag="LP433_001680"
     CDS             9680..10537
                     /locus_tag="LP433_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005846.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10618..10953)
                     /locus_tag="LP433_001681"
     CDS             complement(10618..10953)
                     /locus_tag="LP433_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005847.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(11020..12390)
                     /locus_tag="LP433_001682"
     CDS             complement(11020..12390)
                     /locus_tag="LP433_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBL2005848.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12468..13004)
                     /locus_tag="LP433_001683"
     CDS             complement(12468..13004)
                     /locus_tag="LP433_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2005849.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13313..14794
                     /locus_tag="LP433_001684"
     CDS             13313..14794
                     /locus_tag="LP433_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2005850.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIP
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14897..15604)
                     /locus_tag="LP433_001685"
     CDS             complement(14897..15604)
                     /locus_tag="LP433_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBL2005851.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15683..16021)
                     /locus_tag="LP433_001686"
     CDS             complement(15683..16021)
                     /locus_tag="LP433_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBL2005852.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(16132..17094)
                     /locus_tag="LP433_001687"
     CDS             complement(16132..17094)
                     /locus_tag="LP433_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBL2005853.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKINVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(17109..18440)
                     /locus_tag="LP433_001688"
     CDS             complement(17109..18440)
                     /locus_tag="LP433_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2005854.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18448..19128)
                     /locus_tag="LP433_001689"
     CDS             complement(18448..19128)
                     /locus_tag="LP433_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL2005855.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19347..19826)
                     /locus_tag="LP433_001690"
     CDS             complement(19347..19826)
                     /locus_tag="LP433_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBL2005856.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19953..21632)
                     /locus_tag="LP433_001691"
     CDS             complement(19953..21632)
                     /locus_tag="LP433_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL2005857.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            22180..23682
                     /locus_tag="LP433_001692"
     CDS             22180..23682
                     /locus_tag="LP433_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2005858.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23695..24357
                     /locus_tag="LP433_001693"
     CDS             23695..24357
                     /locus_tag="LP433_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005859.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24458..24661)
                     /locus_tag="LP433_001694"
     CDS             complement(24458..24661)
                     /locus_tag="LP433_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL2005860.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24772..25956)
                     /gene="iadA"
                     /locus_tag="LP433_001695"
     CDS             complement(24772..25956)
                     /gene="iadA"
                     /locus_tag="LP433_001695"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBL2005861.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(26113..27852)
                     /gene="yfcC"
                     /locus_tag="LP433_001696"
     CDS             complement(26113..27852)
                     /gene="yfcC"
                     /locus_tag="LP433_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBL2005862.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(28624..29238)
                     /locus_tag="LP433_001697"
     CDS             complement(28624..29238)
                     /locus_tag="LP433_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2005863.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT         8755 a         6081 c         4922 g         9603 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcggg agtgtttccc gattcgtttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa gcgattgtca actctttttt aaaagttttt tcgatttcgt
      181 ttttcgaaat ctttcagcaa ctcatttatc ataacttatc gtttgttatt tgtcaagaac
      241 ttttttgaag tttttttcga tagaatcaag cttcgcaagt ggttcttttt taacgactca
      301 gttatcttat catgtcgtta gtaacatgtc aataactatt ttttaaattt tttagaaatg
      361 tgatataaca tccacttcag aatcaacgct gttaaattta tcatgtattt cttccttggt
      421 caactataaa ttaagcatta ctttgtgaaa tgatttttcg atcaattatt attattcgtt
      481 atacaaccgt tttcaacata ttttgaaaat aaaatgcact aaaaaactat ctttagcaga
      541 acatttcatt gtattttttg gaccaaacaa taaaaaaaga agtttgaaaa aaattcaaac
      601 ttctttgttc gcttaatctg tattttagaa gaaaggcact ccctctactt cgtaagttcc
      661 aagaacagag cgcatttgac ctggttcttc ccaaatatat ccttcgccta attcttctct
      721 ttgattcttt tgttcagttt caaagacaaa caacggaaca ttttcctctt taatatgtgt
      781 atttgtcaat tccatcaaac taatcttgct aacatcgata tgaactattt cttttaagaa
      841 attaagtata ttcgctaaac cagtctttcc ttcagaaagt tccgctaacg caaattccaa
      901 cttgtcatca attgaatgga ccaaaaattt tttagtacca tcctccaaat gcaacataat
      961 tgtaccagca actcttttgc ttgccaaaat ttccacctcg atcaacttgt tctatggctt
     1021 acataaaaat tctagcacat tttcagaaaa aatacacttt ttatttctta ttttctttcc
     1081 gttctagttc agataatgct tcttctatcc aaataggtaa ctgctccgca atagtggtaa
     1141 atccgatctt acgattttta ttcgtgaaat acctttttct gcgatatgga acagctggat
     1201 ttgttttttc taacgttctt aaagataaac tgattttttt ggaatattca tcaatgtcga
     1261 tgatctgaac tgttactggc tgtccgactt ttaacaatga atggatattt ttcgtataac
     1321 cggattgtac ttctgaaaca tgaataagtc cttgcgtctc gttatcaaga gaaacgaatg
     1381 cgccataagg ctgtatccct gtcacttttc cttcaattat ttgtccaatt ttataagtca
     1441 tctacttccc tctcttcgca tttatcatta tactgtaaat agctcaaaaa aagaagcgac
     1501 gaaaatgact ggaggtctta agatgatcga atttgataaa cagatttcaa gaaaagatac
     1561 agaaagtgta aaatgggacg caattgctga gacatatcaa atggatgact tacttccttt
     1621 gtgggtagca gatatggact tcttgtctcc cggtggggta gctaaagcgt ttagtgaata
     1681 catcaaacat ggaatctttg gttatgccac tctgtctgat aaactatatc aggctatcat
     1741 tcattgggaa cgccaacacc atgctgtgga gttgacgaaa gaaaatatcg tttttacaag
     1801 tggtgtgtta accagtttag ctgcagcagt acaaactttt acaaaaccag gcgattctat
     1861 tttgattcat gacccagttt atcctccatt ttcctctatt atagaaacaa atcaacgtca
     1921 catcgttcga agctctttgc tagaaaaaaa taatcatttc atcatggact tgtctgacat
     1981 ggagaaaaaa atcgaagaaa acaatgtaaa agcaatgatt ttatgcaatc ctcacaatcc
     2041 tggagggcgt gtttggagca aagaagaatt gaaacagtta agcgaattgt gtttaaaaca
     2101 tcaagtgatt ctgtttagtg acgagatcca tcaagattta actttattcg atcatacatt
     2161 tacttccatg ctaacgattg atcctaattt agatgatcta ctagttgctt ttacttccgc
     2221 aaccaagact ttcaatctag ctgcaatcaa aaattcaatg gtatttatca aaaatccaga
     2281 gatgaaagct gattttgaaa aacatttagt gatgaaccaa cagcacgaaa tcaacacttt
     2341 tggactgatt ggaacccaag cggcttatga gacgggtgga gaatggttaa gccaactgat
     2401 tccttatcta gaaaaaaatg ttcaaacagt taatcagttt tttgaacagt atcttccgaa
     2461 agtgagaata atgaaccctg aaggaactta cttaatgtgg ttagatttta ccgcctatat
     2521 ttcagacgac caagaattgg agaacactct tgttcggaaa ggaaaagtcg tattaaatcc
     2581 tggcatcacg tttggtcctt ccggtcatgg gcatatgcgc ttgaatattg cttgtccaga
     2641 agaaacttta ctggaaggac ttaatcgaat caagtatgct ttagagacaa tcgattaaat
     2701 catttattca aaataaaagg acgagacctt actaggtttc gtcctttttc ataattactc
     2761 cgtaccatac caaactattc tgaaatttca attgtttcaa tcactacatc atgtacaggt
     2821 cggtcttgtg gaccacgttg tacatttgcg atttcatcta ctgtgtccat cccttctagt
     2881 acatgtccaa agactgtatg tcggaaatct agccaaggag ttccgccacc tttatacgct
     2941 tcaatgattt ctgatgggaa tccagcacct tctagttgtc caagcatatt agctggcaca
     3001 tttgtgttat ttacaataaa gaattggctt ccgtttgtgt ttggacctga atttgccata
     3061 gataaagctc cgcgaaggtt gaacagttca cgactgaatt catcttcaaa actttcgcca
     3121 taaatacttt cgccacccat tcctgttcca gttggatcgc cgccttggat catgaaatca
     3181 ggaataacgc ggtgaaaaat cacgccatca taataacctt ttttggaaag ttcaatgaaa
     3241 ttttgaaccg tcttcggtgc tagttcaggg aataattgaa cagtaatgtc accacggttt
     3301 gttttgataa cagcttttgg tcctttttca ctttttaaat ctagttgtgg gaatgccata
     3361 ttgtttcctc ctaatatttg catacttcat aataataata acataatacc taacctctcg
     3421 taaaaatact agatttgttt tcttttattt ttcatcacta gatacattct ataacttacc
     3481 gtttcgattt cgaattcaaa catttttgag aagcattctc aattaaattc tgctatagtg
     3541 tgaaaaggga ggaattttta tggaaatcta tgacattaca atcatcggtg caggtcctgt
     3601 agggatgttt gccgcttttt acgcaggaat gcgccaagct aaaacaaaaa tcattgacag
     3661 tctacctcaa cttggtggtc aattagcaac tttgtatccc gaaaaatata tttacgatat
     3721 tcctgggtat ccagcaataa aagcaagtga attaatcgat caattagaaa aacaattaac
     3781 tacttttaac catacattcc atttaaaaga agaagttctc tcgcttactc gtgaagacga
     3841 agttatcgag attactacaa ataaaggcat ccattattcc aaagcagtca ttttagcttt
     3901 aggaaatggt tcattccagc caagaaaatt gaatttagat aatgctgaat catttgaaaa
     3961 ccacggattg gattatttcg tgaatgattt gatgaagtat gctggaaaaa aagtcgctat
     4021 tgctggaggt ggtgattctg ctatcgattg gacgttgatg ttagagccta ttgcaagcga
     4081 agtttacttg attcatcgtc gcccggaatt tcgtgcgcac gaacatagtg tatcacgctt
     4141 gaaatcttca tctgtcaact tgcttactcc ctatctcatc gatggattat caggcaataa
     4201 tggggaactg acagatatcc ggttaaaaaa agtgaaaagt gacgagacga ttgatttgat
     4261 gattgattct ctgatcgtca attatggatt ctcttctaat ttagaacatc tttcttcttg
     4321 gggacttgat agtaccagaa atgccattac tgtaaaatca gatatgtcta cttctattcc
     4381 aggcgtttat gcagctggtg acatctgtac ctatgaagga aaagtgaaac tgattgctac
     4441 tgggctcggt gaagcaccta ctgcagtgaa caacgcttta cactatatta atccaaagga
     4501 acgaactcag cctggtcaca gcacaagctt atacgataaa aatcttcgtc ctagttgatt
     4561 ttttatatct ctttgcattt caagttaaac ccgaaagcag tttcttgcat ttttttcatg
     4621 ttccgttaac atgaaataga gaaagaaaaa ataaaggggg agcaataata tggtcgtcaa
     4681 aactgagact ttagaagaaa aggcaagaga actattgaag gaacgtggcg taactgtaga
     4741 agatatcgca caacttgtca tgtttttaca aaaagactat atttctgatt tgactttggc
     4801 ggattgtact gaaagtgtca acagcgtgct aacaaagcgt gaagtacata acgccattat
     4861 cactggaatc caattagata tattagcaga aaagaaaaaa ttgatgagtc cgttgcaaca
     4921 tattatcgaa gatgacgaag gcctttacgg tatcgatgag atcctagcct tgtcaatcgt
     4981 gaatgtttac ggtacgatcg gctttacgaa ttatggttat atcgacaagg tgaaacctgg
     5041 tattttaaaa gaactaaaca gccacgatgg cgttcatgtc cataccttct tagatgatat
     5101 cgtcggagcg atcgccgctg ctgctgccag tcgattagca cacaaagaac cagaaaaaag
     5161 aagtcgcctt actcaataat tcaacaaaaa aagaaagaaa acgtctattt agacgagttc
     5221 tttctttttt gtttgtttca agctattttt tcctaagaaa agaaaaacag caaaaaataa
     5281 ttctaataat acaaaaaata agataaagct atgcatgaaa aattcttctg gaagtacatt
     5341 gatgattgga tcagtaacgg gatcgaataa ccagtcatcg ttgttgaaaa acgtttcatg
     5401 aaaaaggata aaaaagcgat caaatcctat catcatgaaa aaaccgaaaa caactggcag
     5461 taacatgccg atttgaaacg gacgaatcaa ccgccaaagc cgatcattct tttgcaaata
     5521 tttgataaac aaaatactcg ggatcaaagt gatgaaaaac acagcataat ccactaaaaa
     5581 caaaattttc acttcataaa agtgatgggc tccgctagca gaaactggga aatctggcaa
     5641 gctgaggatg gttttgaagg gattattgag ataattcatt aggtgatcaa aatttttcag
     5701 taacgtctct tgatctaaag aagtataatc caaaatttgc aaatgtccga tatcaaatac
     5761 gtatagtggt cgaaagttga tcgtcacacc aactgccaga ctgatcagtg tcagaaatag
     5821 gctgaacaat ccagcatatt ccatccactg ccatctcgaa tttttcatat tagaagctcc
     5881 attcatccag tgattgtttc acataggtag ctgggatagg caacccaggt acatcttctt
     5941 cttttgtaaa acctgataaa acgagcaaag tatctatatt attgcgtatc ccagcttgga
     6001 tatctgtttc atagttatct ccaaccatga ttacttcttc tttttgcagc cctaatactt
     6061 caacggcttt atccataatg atggcttctg gttttccgat gtagatcggc ggcgtttggg
     6121 ttgctgtctc tacaaaagag atgactgacc ctgctccagg aagaaggccg cgttcagtag
     6181 gtatattctt atctgggttc gttccaatga aagtagcacc tttttgaata gcaagtgttg
     6241 ctttaactac tttttcatag gtcagataat tatctaagcc taccactaca tagtcaggag
     6301 cctcttcttc ccatgtaaat ccggcagcta aaatcaagtc aatcaatcct gcttctccga
     6361 taacatagac ttttttccct tttccatctg ctttcataaa atcgattgtt gccaaagtag
     6421 ctgtgtagac tgtctctgga gctacatgaa tgtcaaactc atctgctaga cgattagcta
     6481 ctgtttctgg tgacttagtc gtgttattgg taacaaacaa gaaaggtaat tttctttttt
     6541 gcaattcttc cacaaatcgt ttaccggccg gtatgggttg tgtcccacga taaatcgttc
     6601 cgtctaaatc aattaaatat cctttatagt ccattcatcc actactcttc cctttttctg
     6661 atcgtaaatg ctgtttttgt tttttctact tgtttaggtt gttcttgttt ttttactttt
     6721 tcagaggttt ttgctgactc tgtttttcga tttttaataa ccggtttttt gcgattagat
     6781 gcgactggtc cttttttctc atcgatatac gcacgattat ggtttttttt cttttttcgg
     6841 cgctgagttg tcttttcttt tttaccgccg attctctcga tgacaaaata cgcacaacca
     6901 aaattgcaat attcgtaaag atagtcttcc aaggaatcga ttcgctgatc tggatgcgcc
     6961 cgtcgattat ccgcttggaa aaatcctttt aggcgtagtt gttcataacc ccaatctcct
     7021 acgatataat catatcgggc tagtacatca ctgtaacgtt ctccaagctt ttctgcatta
     7081 aatccttcac gataatcgga cacaagccga taatgtcttt cacctatcaa aaaattactg
     7141 tcatctaaca gtgtcactag ctcgcctttg actttttctg ctttaggctc ctcaacgatt
     7201 tcttccaaag cagctgtcag ttcttcggtg actgttgttt cctgttcagc tgatgatttt
     7261 ttcttagcaa tttctgtttt atgctcaacg ttctgctgtt cattttgttt tgcagacatg
     7321 cgttcaccac ctatcttttt tattatacct tgtttttatt tgattgggta gtgagctttc
     7381 aagtaatctc ctaccacact tcggataaat tcagggaaca aaaattcatt ttttccagca
     7441 atctcaatcg ttggaaaaaa tggaacaaac atcaaatgat ctacggtagt aaaagtataa
     7501 tttttattca gatcgattgg cttgttcttc caaaagactt gatggttaat agaatcatat
     7561 gtgattccat tatagaccat ctgcccaaaa atcttaccgc gaaatcccat tcccttcata
     7621 ggatagttac gtaaaaagtt acgatttttt tctatttcta aaactaagcg gatcagatca
     7681 tttccaccca atgtgacatt taacaagtgc atcggatgcg gcaacgcagt gtgaagctga
     7741 tcctgattga cccgcccttt tggaatttca gttaaaaaca gaccactgtt taatattgct
     7801 gcttccgtct ttcctcgttc tttcaccgcc tcaaaggcta cttggataaa cgaatgctca
     7861 ttgaagatat ctagactcag agaaaatggc aaatctgcta cttctttttc ttttaataat
     7921 tcatgcccac gttctagata actatttatt tcttgttcat cttctgtaaa agctgtcatt
     7981 gtttcggtag ggatggcttt ggctgaatgc ttaaggattt ttttctcttc atcgatggtt
     8041 aaatggactt caccgacata ctgcccgtac tttccagcgg ctgctatttg gacatcattg
     8101 attacgtgac cttctctgaa taaatgatgg gtgtgcgatc ctaaaataac atcaattgct
     8161 ggtatttctt ttgcaatttg gaaatcatcc tgaatcccga gatgactcat caaaactaaa
     8221 acatccactt gtgaacgtaa atcttcgact aattctggca aaatatcata aggattccgt
     8281 atgtcccagc cattcggatt ataagtaagc ggaaatggag cagtaaatgc aattagtccg
     8341 attttcgtct ggtgtttcgt tgtaatgatt ttatatggtt tcgtccatgc cggtggctgg
     8401 agcgtatttt tatcgaataa gttatccagg atgatatcaa actcagcatg atcgtataaa
     8461 tgattcaact cttctttgga atttcctacg ccttcattgt ttcctatcgt cgctgcatca
     8521 taaccaactt cattcatcag caagatattt tcctgtccat tcgttgcttc tgacaatgga
     8581 tgccaacgat ccacaaaatc acctagatct actgcaatcg ttgtcgtttt ttctttcttt
     8641 tcgttttctc gtttacgttg atccaaaaac cttctgatcc ttggccaatt ttctaaatga
     8701 gaatgcagat cattcgtatg taaaatcact attttttcca tgtaccctct cgcctctctt
     8761 tatctttatc ataccatagg cagctttttc ttccattgaa acaagctcta tttcagagtt
     8821 tttcctgcct tgaagcaaat tgtataagta caatattcga taaatcagtc tggctaaaaa
     8881 atcaggaaca ttcattttta cagtactata aaaataaaaa aaacagaccc gaaagtctgt
     8941 tgtcgtttca ttataatcag acacatggcg gaacctgctt agtgctgctt ccttccagac
     9001 ctgacacgct tcacaagccc accattgtcc tagcctttcg gcaaagaata gtatacctta
     9061 tttttcattc gttgaccagt ctttttttaa tttctttttt cgctggcgga gctttcggaa
     9121 aaagtcagtc aaaatcatcc cacattcgtc ttctaaaatg ccaccttcta catatgcttg
     9181 gtggttaaac cgctcgtcct ccaaaagatt catcaaggta ccggctgttc cgccttttgg
     9241 atcatacgcg ccgaaataaa cttctgctac acgagacaaa atcatcgcgc cgctgcacat
     9301 aggacaaggc tctaaggtaa caaaaagtgc agcatcttcc aagcgccagc ttcccacttt
     9361 ttcacaggct tccttgattg caagcatttc tgcatgtgta gtagcatctt gcgtggtttc
     9421 tctaaggtta tatcctcttc caatcacttt tccatccaat acaaccactg ctccaatcgg
     9481 aacttcatga agcatttctg ctttctttgc ttctgccaat gcaaggcgca tccatttttc
     9541 tttttctact gcatcaagat ttgtatttac caattaccct tccctgcctt tgttttttct
     9601 tgttttactt tagcatatga taaaaaggct gtaactaact tttttttcta tggtaaaata
     9661 aatacaagag gtgaacaaga tgaaaatgga taaattactt gctctttacc cacaagcaca
     9721 gaaaaaaaac tctccagcat cagaagcgga tatcctttct tttgcaattg atgatgcttt
     9781 tatctggatc aaacaagatt cattatctca acaagaaacc agccttttga aagcgttatt
     9841 ccctgtaatc aacgatcaaa aaaaacaccc atggtatcac tatcttttta aagatgcttc
     9901 ttgtgttcaa gaaaaaagct ttcgtttgat ccagcttcac gtcgaatcaa aaggagaatt
     9961 cttaaaaaaa gaatggcaag atactatttt ggaattattt cgctattctg ctgatttctt
    10021 tttttataca gacacagatg cgctcttagt cgaacaaata aaccgtgatt atcttgatgc
    10081 tactgaaatc aacggtattt ttctatcttt agatgctgat tttgatacga caacgtctgt
    10141 attcgttggt tctttccatt cacctggcac cgacctcgtc cctttgtttg ctgaagaaag
    10201 aaaaattttt ttaacagagc aaaacaatct ttatactcac agccgtactt tttctatgca
    10261 agatgtggct ttacattact atacaaaaga tactgtaaaa gatagtaagt tgatcaaaag
    10321 ttacatagaa ctgatcaaac aaaatgaaat ggaagtgatc attcaagaat tatggaatga
    10381 attaggcaat gtcagctctg ctgcaaaaac actgtttctt catcgtaata ctctaaaata
    10441 tcgaatcgaa aaatttcaag aacagtctgg tttcaatcta aaaaaagcca acgatttact
    10501 gttttgctat cttttattgc ttcatgaaca taattaaaga tagattaaag gggttgtgac
    10561 aataattttg tcacaacccc ttatttcgaa tgaatagtgt tcaaaagcta gtttctctta
    10621 catcattttt tcaacaaaat gcattagccg gtcttttaca tcttcggttg aatctttgat
    10681 tgaatcacca taaacagaga ttttcttttt tcctgatttg atttttgcta acattcccat
    10741 caaagaatcc aagtcactat ctgaaagacc atctacgatt tctagtaatt tttcatttcc
    10801 atcaaatttg tcatagacga atttttttac tttcgtccga gtagtcatat gatggatctt
    10861 ttccattact tttcccgata caacgactgc tgtcgctaca ctggcagcgg ctgctacgct
    10921 taatccgatt gttacttttg ttgatgtttt cataagtatc agctcctttt tatctatctc
    10981 catcatagca tagacaaaaa aataaacgaa ctaatccact cagtgaaatc tcaatccttt
    11041 agggaaaaag ttctttactg ttccttttac ttgtttccca aatccgacag gtatcttatc
    11101 taatactagc aaaacccatc cttgattccc atcacgttga aatgtttctc ctgctgtgta
    11161 agattgccat tccttttgag tgatcggcaa gcaaggtata ttctctatct tttttgtagc
    11221 aagcgctaat gcatagctag gttcaaatcg attctttttg aaatctccta aatgcaaacc
    11281 tgtacgtacg acttttaaac catcgagaga aggggctaac tcaggaactt cccaaagatg
    11341 gtcgttgaac actaaaagtc ttccagtagc ttcataatga aaatcatttg aaaactccgt
    11401 ccagagtttt tcctgctctt ttgtcatttg cactttactt ttttttcgtg tcttcttttc
    11461 tttatgcatc tgattttgtc catgaaaagt cagctttgca acaaaatgtc cttcaccctg
    11521 atctttatga ggccatatac gtattgtttt ttccaaacca gctacgcttc cccattcaga
    11581 acgtcctgaa ctaacggatt gagtcaaagg aatctcctca atcgttactg gataattttc
    11641 tacaagccag ctaatgatct cttcattttc ttctggtgca aacgtacaag tcgaataaat
    11701 cagttgtcct ttatttttta gcatttttat tgctgaagac aaaatctctt gctgacgttt
    11761 ttgacagtat agcggagatt cttctgtcca ctcttttatt gcatttggat cttttcggaa
    11821 cattccttct cctgaacaag gagcatcaac cacgatccga tcaaaaaagc ccgaaaaatg
    11881 agggacaagt tctgcgggtg catgatttgt cactattgcg ttcgaaactc cccatcgttc
    11941 tatattttct gataaaatct tcgcacgttt cggaaagatc tcattcgtca ctaataaccc
    12001 tttccccttc atttgagcag ctaattgggt tgatttacca ccgggagccg cacacaaatc
    12061 caaaactttt tcaccgggtt ttgctgcagc agctgttcca acgatcattg cacttggttc
    12121 ttggctatat tcatacccag cttgatggag gaaagacttt ccattgacag tgccaagaaa
    12181 tccctcattg ctgtagggag cgggttgtaa ttcttcgcta tggtaagttt ggaccatgtc
    12241 caatcctgcc ggttttagtg gattccaccg aaatcctttt ttcacgcttc cttgttcaag
    12301 cgcagaaaaa aaatcggatg cttcttcgcc taaaagaaga cgatattttt tgataaattg
    12361 ctgtggtaac gttgtcgctt cctccttcat tccaatgttt cgttagacat tttacaatct
    12421 tttttacgaa aaataaaggt ggctgatcta ctttttcatg ttgctgccta aggtgactgt
    12481 tcctttaaga tattttccaa gtattcatcc gtcacctcgt ttttatccca aacagcgttc
    12541 atcatttcaa gaaaatcttg agaagaatca tctgagcgca aacttcccaa tgcattaagc
    12601 cataccaatt caagcgactt ttcttctttg atcttcgtgt gacctttgac atatgagaaa
    12661 aatggccgct taaatagcga atccatgtct aaatcagatt ttgcaatgat ttcacgaata
    12721 ctttcatgga tagaaaaaaa atctttcaat aagtagacaa tgcttaaaac atcatcggaa
    12781 ctgcattcag ctaagtagtt ttcaaaataa acagtgattt cttctaatat cttctctttt
    12841 aacccgctga ttgatttgaa atgtgtataa atcgggtatg tagaacaacc gcagaactct
    12901 gctaactctc ttgcagtaat tgacttcatt ccatattctt ccacgtatac catacttttg
    12961 aacagcaaat attctttact ataatttgtt actctcccca tcattcttac ctccgtctct
    13021 tttcatctac ccataaataa ataacataaa taattctaaa aatattattg ataattatca
    13081 aaacatattt agttatatcc attaaaaatc aatttttccg ccttaaaaac aagaatatct
    13141 tgacaaaata ccctaggaaa taaacaatag aataaacaag gtaacaaaaa aattaaataa
    13201 cgttatataa aaaagaaggc gacactctgt gagaataaca cagactgaaa tgactttcca
    13261 ctcacagttt ttgtctaact atatacaaaa acagaataaa aaggaggtat ttatgctaat
    13321 tgaagcaaga aaaaaagagt tacttgttct acaaatggtc attcaaaaaa ataattgttc
    13381 tttacaagaa ttatccaatg acttacatat tccaaaacgg acaatcaaag aactgatccg
    13441 aaaaataaat gtatcactca agcaattttt attgattgat gaatttattt attctaatca
    13501 taaaggagag atccaaacca aagaaaccga tcaaactaaa aagttagctg ttttttctaa
    13561 gttaaaatta tgctacctaa aagaatccaa tcgttttaac tatttgatgt tactaatcaa
    13621 ttatccacaa actgctgtac caaaaaaata tttacttgaa caactttata tatcgccctc
    13681 ctatctcgaa aaactgacaa aacagctcaa tcattcctta aaaaaattcc atttacggat
    13741 cctatctgta aaaaattgct gtactcttga aggaaatgag ttatctatcc ctctctatct
    13801 ttactttttt ctttcagata catttggagg taacgattgg ccattttcct cacttgaatt
    13861 aaatgcacta aaaatgaaca gtacagatga gcaaatagaa aaaatttcaa aacaagaaaa
    13921 aaatatctac ttgctgttaa ctttattcat attacgaaac aaacaacagg catattttcc
    13981 aaaaacttct tctgaaatca ctgaattgat ggacttattg cagcatacac atgattattc
    14041 agaatacttt acttcttttt cagtgagtcg cccttgtgaa gagacagaaa cagagagagc
    14101 ctactttaat tattttttct attgtttttt tccaaatcaa atctcttttc gacaaaaaca
    14161 ggagattggt tttttatttt ccacaagcaa aaaccttatt tgtcgacaag tcggtcaatt
    14221 gatgacttac ttaactcaac agtttcctct caaccattta gaaaataaaa taccaattta
    14281 tttttatttt cttgtgttgg cagttgtttt tttcgaactg ttgggtgaat ccagcagtag
    14341 tttttctaca ctttgctttc cagaagccac gtccaatcat tctagttctt ttatacagga
    14401 aaagaaatta agagaaaaaa tcgatacaat tttttcaaaa aatggggaaa gaaaccaaat
    14461 cagtcaatac cttagtcaat tgatccaaca cttactacaa acagaaacga aagagcagtt
    14521 actcatccat ttgcagataa ccaaacagtt tacaggaaat tatcatcttc aaagccattt
    14581 gcagcagtta tttcgcaaag atgctgttaa aattaccgca tattcagaac atgctgattt
    14641 gatcattaca gatcagcatg agaaaatttc agatgaaacg gagactttct atctggatac
    14701 aacgcacaat acagtgttat ttggcaagtt aataaaagcg gttcatgaac tgtatatgaa
    14761 aaaaggttat gagaacaaaa caaagaggat gtgacaaaat tcttgtcaca tcctcttatt
    14821 ccaaataaat ggtattcaat cagctaactc tcggtattag ctcagatcaa agcgctgatt
    14881 tcacaacttc tttattttaa tctcttcggt tgccgccgaa caataagatc aagcgcaaca
    14941 gctgcaggaa tgtcgaaagc gctgctgcaa cataagtcag tgctgctgca aataatacgt
    15001 gtcttgccat cggtacttct tcttccgtca gtagtccgcc ttcactcaaa atttggattg
    15061 ctcgccgaga cgcgttaaat tcgactggta atgtcaccaa ttggaaaagt aatgctaaag
    15121 aaaaagcgaa aatcccgata ttgattaacg tagagttcca gctaagcaat acacctacca
    15181 taatcaaggg gaacgaaatc atcgaaccaa agttagctgc tggaacaagt gctgcacgaa
    15241 tcttcaatgg gacataaccc gaagcatctt gtaccgcatg tccgcattca tgagctgcta
    15301 cacctatcgc agcaactgaa gtagactgtg cagttgcttg agacaaactc aacatcttat
    15361 tacctgaatt gtagttatct gtgagatctc cggcaatttg ttgaacaccg acattattta
    15421 tctgttgact ttgtaatata tattgtgctg cttgtgtacc agtcacattg tttttgcttc
    15481 tcacttgatc gtattttcgg aaagtactat tgacgtacgc tgacgcaatt ccggaaataa
    15541 ctaatccaag aatgaccaaa agaaatgtcg gatctaaaaa accatacatt ccataaccat
    15601 acattttcgt ttcactcctt ttcgtttact ttattttatc attagtagta ggaaaagaat
    15661 gtgaaaagac cttgaatatt ctttaattct ttttcacaaa ttccgatttc agtttcatcg
    15721 gtccaaatcc ttctaccttg caatcgatat tatgatcgcc ttctactaaa cggatgttct
    15781 tgacttttgt tccttgttta atggcacctg acgcaccttt tactttcaag tctttaatca
    15841 ctgtcacgct atcgccctct aacagacggt ttccatttgc atctaatacc actaatccgt
    15901 cttctatgac agtttcttgt tcttctttgt tccattcgtt cccgcattct gggcaaatca
    15961 acaagcctcg atcttcatat gtgtactctg agccacattc tgggcaattt ggtaatgtca
    16021 tcttctttct cctttaaaat ctttagtgag cactattgta acggaaaaag aagatcttga
    16081 aaagatacat ttgtgatttt tactacaaaa ggcacgtttt cgaacgaagt atcattctgt
    16141 ttttctgctc ttatacgatt ggcatatatc ttggatctct ttatagattt cctctacttc
    16201 tgctaaatct tttgcattcg caccacttgc taatggatgg cctcctccat gatggcgttt
    16261 agccaattca ttgatgatcg gccccttaga acgtaaacgt acgcggtaat accctgaagg
    16321 ctgctgaaca aaaatccccc aagccagcac ttcgtcaatc actccaggaa gtgaaacgat
    16381 cgaagctgtc tctgaatcat cgattccata tttatcaaga atttcttgcg gaaggattat
    16441 tcttcctgca ccattttcat ccacctggat attttgataa agataaccgg aaagtttagc
    16501 gactttcatc ggcatttgtt caatctctct gttcaaagca cttgcatcaa atggataatt
    16561 tctcaatatc gaagcaatct ctaatgtacg ggacgtcgtg gagggataca aaaagcgccc
    16621 tgtatctccg acgattcctg cataaagtaa ccgtgcagcc ttaacgttta tctttaaaga
    16681 ttcaggaaac atcaaagcaa attctgcaat catctcacta cagctacttg cttttgtatt
    16741 tacccacaca agatctccat aagggtcatc attgggatga tggtcgattt tgatcagttt
    16801 ttctgccaac tgatatcttt gatcactgat tctgggtgaa ttagctgtat cagtcacgat
    16861 gactagcgct ccttggtaga agacatcttc aacttcttgc atttctgcta aaaagcgaag
    16921 cccttcaatc gtttcaccta cttgacgtat ttctttttct gggaaacttt cccgtaatag
    16981 ttcggctaat cctacttgtg atcctaatgc atcaggatca gggcgcaaat gcctgtggat
    17041 aatgatttta tcgtattttt ttattgtatc tactatttct tgctgtactg tcatttcact
    17101 cctgctttct aagaacgttc cattacttga caaacaacga ttgctttgga aacgatggtg
    17161 ttttcaataa acacttcgat atccagttta gcggaacgtc tgccgatttc caatacacgt
    17221 ggacgaatgt ctaattcgct ttccaattgg atcagccgca aataatgtag gttcacttgt
    17281 tcaatcaaga tatttcgttt ttggttcatc accattgttt tttgtgcgac atcagaaatg
    17341 atttcgctaa gtacgccaaa agaaatggtt ccaacgccat tgaccatttg tggtgctact
    17401 acgaatttga acttagggtt ttccaaacga tttccttcac ggtcagtatc aatcgtatgg
    17461 atatttccag atatctgatc cgaaatcgta tctgcaatct gcggttgtcg ctggacaagc
    17521 tgcatcgctt tcattacatc ttgccgggta atcaagcctt ccaatgtcaa gtcatcggaa
    17581 acgaccggca tgacttctag cccatcccag atcatttgat ggctaacaga ggcaatactc
    17641 attgttttct ttacactgat tggttctttc gtcatcaccc gatcgatgat ctggtttggc
    17701 gatttcccta aaacatcttt tgccgtaaca atccccatca aacgatgatg gcggttgacg
    17761 actggaaaac gcgaatgctg cgtttcttct gacaaacgct gataatcaga aatcgtatct
    17821 gtctgctgca aataatgagt cttttcagct ggcatataga tatcactgac aagcatgata
    17881 tcttttttga tcaattggtc gcttaacgct cggttgatca tggttgcgac tgtaaatgta
    17941 tcataagagg tgcgtaagat cggcatttca agatcatcag ctagctttgc aatctcagca
    18001 gtcgtattga atcctcctgt gatcaatact gcggcgccat cttccaatgc taatttttgg
    18061 acttccgccc ggttgccgac gatcattagt gatcctggcg taatatagcg ttccatggca
    18121 tgtttagtca tcgcgccgat gacgaattta ttcaagacct tgtctaatcc tgccgccccg
    18181 cctaaaacgt ccccttcaat gatcctgacg acctcgccaa atgtcaaacg ttcaatatgt
    18241 ttttttaatt tgcgttcgat acggatggtc cctactcgtt gaattgttga aactagtccg
    18301 acattttctg catctttgat tgcacggtac gctgttcctt cactgacatt caattctttt
    18361 gcgatgcttc ttacagaaat tcgattgcca acaggtaaac tttcaatata ttctaaaatc
    18421 aaatcatgtt ttgtcgccat tttctgccta cacttccagc gtttccgaga cgctcattat
    18481 ttttccttca ctatcttcca gtaactctac aaaagattcg ggatcttgtt caatgacagg
    18541 gaaagtattg taatggattg gaactacttt cttggcacga attgtttgcg cagcctttgc
    18601 tgcatcttct ggccccatcg tatagttatc gccaatcggc aagaaagcga catcaatatc
    18661 gaattcttct gcaagcaatc ctagatcact gaaataagca gtatcccctg catgataaat
    18721 cgtttttcct tctgcttgaa taataattcc gctaggctcg cccatatact gaacgatacc
    18781 gtctacttca tagcttgaac tatgctgtgc atgtacgaat tttaccacgc cgaatggaaa
    18841 cgcatgtttt ccaccgatat tcataccgaa tgaatctact cctctgctgt tcgcataatc
    18901 agcaatctca acaatactga taattgtggc ttgattttct tttgcaatag gaatcatatc
    18961 tcctatgtgg tcactatgac catgagtaat cagcaaccaa tctgtcttta cttcttctgc
    19021 agttaagtct gtcaatggat ttcctgtaat aaacgggtca atcatcacgc gttggccatt
    19081 ttccatttca attgttaaac aggaatgtcc atgatacgta attttcatat tttacacctc
    19141 gcgttttctc tgtatctttt ttattaaaaa cgatttcatc acttgcacat caatgaaaaa
    19201 atatagctgc taaatatatt ttcattggat tgatagtaca gtatgtacaa agcaattgta
    19261 acagataata caggatgcac caagtaccaa gcagatataa tctcaagttt gaggtctctg
    19321 ctctgcttag cttctcttct cgtcccttaa ctaattaaat cagcgtaaat aggatggacg
    19381 atcttttcta aatcggctac ttttatccga aggcttctcc cgatttcacc gcttgacaca
    19441 attacttctt ctttttcttt taaagaactg tctgctaaaa aacaataatc aggatgtgcg
    19501 agttttattc caataggggt gtttgctccg tggggatatc ctgtatgcat taatacaaaa
    19561 tccattccag gaaaaccaac tttacgatct ttcgtcactt gtctcgtttt tttgtaatct
    19621 aagtgatcgt tcaaaggaat caatgcgatg atcaccccag ttttgtttcc tttcactacg
    19681 agagttttac atatcaaagc tggatcaatc cctctttttt gtagttcttc tgtgaaagat
    19741 tcttctacca catgactaaa atcaagtggt tgatagctga tcttttgttc ttctaaataa
    19801 cgttcgactt ttgtttgact catcattgat tcactccctt tattctatcg tttattataa
    19861 agcgagggat gctgtattca aaaattattt gtttttcgca aaaaaagagc aagacgagca
    19921 ctctatagag aggttcatct tactcttttt gtttattttt tatttcgacg ttgagtagct
    19981 tccataatga ctggcaagat cactgggcgg cgttttgttt gttcaaataa gtaacggcct
    20041 aattgatctc ggatgtcttg ctttaatttg ctccactcaa aatcattgct ttctaaatgt
    20101 ttctcaacga ttgtttcaat catattgctg ctttctttca tcagatcacg gctagctttt
    20161 acgtaaacga atccccgtga agtaatttga ggttttgaaa tgattttctt ttctcgccga
    20221 ctgatagtga caaccgctac gaaaatcccg tcttctgaca agatttttcg atcacgtaaa
    20281 acaatgtttc cgatatcacc tatgcctaat ccatcaatca ttacattttc tgcacttgta
    20341 gttcctgcaa cactcatacg cttgttctta tattccagca cgtctccgcg tccagtaata
    20401 tagatatttt tgtatggcat ccctactgca tgagccaaat ctgcatgagc agctaattca
    20461 cgatactctc cttgaactgg cacaaaatat gttggtttca tcaaattgat cattaattgc
    20521 aagtcattag gattggcatg gccagaaacg cgcatattct cagagatcaa cttcactgtt
    20581 ccaccagctc gataaatgat atcttccgtt ttcgccacga tggtttccat cgcgatgctt
    20641 ggcgtagtag tgatataaac caaatctcct tcttcaatct tgacattacg gtgtgtaccg
    20701 tttgccattt tttgcagaga cttgatgggt tcacccattc ggccagtttc taaaatgatc
    20761 agttcttctg gatcatagtt tttcatgtct ttcaacgtaa caagcagatc ttcacttggt
    20821 aattgaagtt tttctaaacg catcgctgtg cgaataattc gttcgaaatc ttgaccagtc
    20881 aagacaactt ttcgttgtgc tttttctgct gcatccaata cttgttgcac tcgttgcaaa
    20941 ttacttgcta cacaagcgac gatgatacgc ccttcccaat atttgatcgt atcaaatact
    21001 tcatctgcta tttgggcttc agaagctaca ggctgaggat tttctgcatt tgccgattca
    21061 cttagtaagg ctaagactcc ttctttgccg atttccgcca atcgtgcata atctgtttga
    21121 tacattggga tagccgtttg gtcaaattta aaatctcccg tataaacgat actaccttct
    21181 tttgttttca gattgatccc cactgaatct ggtatcgtat gagtggtacg gaaaaagctc
    21241 actactgttt caccaaagtc tatttctgta tgctcatcta ccacatggaa atccttaaat
    21301 cctttggctg cttcattacg actgacattc aattttgcta actcgatcgt caactctgtc
    21361 ccgaatactg gtacagaaat ttttgacaac aagtaaggaa gtgccccgat cgcatctgca
    21421 tgtccatgtg ttaaaaagac accagctaca cgatcaatgt tttcttctaa atacgtaaaa
    21481 tcagggatta cgacgtcgat ccccaacaac tcattttcag gatattttag cccacaatct
    21541 aaaataaaaa tatcctcgcc cacttctgcg acatacatgt tttttccatt ttcacgaacg
    21601 ccgcctaatg ggataatttt aatggtactc acaaacttca cctcttctta tgacatccaa
    21661 gtttaaagat gtcgattttc ttctttatct aaatatatga gccattccaa tgaagcatat
    21721 gcaaaatcac tatttctcaa cttatggaga atcagcagga aaattaccag cacatccgcg
    21781 ttctgacagt tggatgggca ttttattttg gatatacttc attaacaaaa tggatctttt
    21841 gcgaaacgct atagccagaa tacttatata agtattcagc tgttccccat tattatacaa
    21901 caaataaact aaatcgctag tatcagcaat tgttagaaca actatgcacg taaaaatccc
    21961 tctgtagcat ctaggatttc ttttgctatt cctctttcat ttcttcttcg tcggtttgaa
    22021 acatactttt ttcattttac cacatttttt gcaataacta tagtgacttt ttatatatac
    22081 agaacctcat gttgatggtg tgcaaacagc ataagattta agctagcttt aagataggtt
    22141 gtctattatc aaatgcatct actaggaggg atgcaaaata tgaattttat gaaacgtgca
    22201 tggaaaagta caaaagtaaa atggggacgt tcattgttat tgtttgccgt gttcacagcc
    22261 attcttattt ttgtgctagc tggcctcacg attcgaagcg ctgcagaaga agcagcgaat
    22321 caagcacaaa aagaagttgg agcaacagtg actttaagtg ccaatcgaga agcttcattt
    22381 aaaaaacagg aacaaacttc ttcaagcggt tctaccactg aagaacgtcc agatccaggc
    22441 agtttttctc ttacaccagt ttccttaacg gacgcggaaa aaatagctga attagataat
    22501 gtaaagagtt attcctttga aagttccgcc tcagctatgg caaaagatgg aataactgcc
    22561 atcactagtt ctgattcaag tgaagacagt tcagaaacta ctgatgcagg cggtgaacct
    22621 gctggaggaa tgggcgggaa tccgcaaatg actcaagcag actttcaaat cagtggtgtg
    22681 tcagcaactg cacaaaatag taatttttct gatggaacag caaaaatcac ggatggtgaa
    22741 ggaatagatg acagcgacaa aggcacaaac aatgtagtca ttgattctac tctagcagaa
    22801 acaaatgacc tggcagtcgg agatactttc acaatcacga gtactgaaga tgaagatacc
    22861 acttatgaaa tgacgatcaa aggaatttat gaatccagcg aaacaagcgg cagtatgggt
    22921 atgaaattca acttcatgaa tccgtcgaat acactttaca cttcttacac ttttgcaaat
    22981 gaactaaatg ggacatctga cgataacacg atagattctg ctatttacac tctatctgat
    23041 ccagataaaa tggatgagtt tctcaaagaa gctgagaagc tgatcgacac agatacattt
    23101 agcttacaat caaatgattc catgtatcag tcaatgttgg aacctttaaa caacgtggca
    23161 agtttttcta aaaatgttgt tttactagtg gctgtagccg gtattatcat acttactctg
    23221 atcattatga ttaccattcg ggagcgtcgg catgagttag gcgtcttgct atctttagga
    23281 gaatccagaa gtaaaatcat tctccaattg tttaccgaag tggctatttg tatgattctt
    23341 gcattaggag ttgcttcgct tagcggaaac gtcgtcgcga atgccgtggg acagcagcta
    23401 cttgaccaac agacagaaac cacgacacaa aaccagcaag ctcctggcgg tggacaaatg
    23461 ccaggtaaca gacaagaaca aggcggtcaa cgcgatggtc aacaaggaac cacgaataat
    23521 ccatttgctg tttctgatca agtcagcgaa ttggaaatca atgtcaaacc tgcacaattg
    23581 ggactattag ccggagtagc atttggaatc agtctgtttt ctgtcttttt agcttctata
    23641 gggatattaa gattaaaccc aagaaaaatc ctattaaact aaaggaggaa tttgatgtta
    23701 cggacagaac aattgggatt ttggtatcaa gatccgcaag atgcgcttta taaagatgta
    23761 gaactgaatt tcgaagctgg aaaaatgtac gctattttag gagcaagtgg ttctggaaaa
    23821 acgacttttc tttcgcttat ttctggacta gatgcaccaa aagaaggaaa ggtatactat
    23881 caagatcgtt cactgaacaa aatcgggtta agaagttatc gtaaaaatga tgtctcgatt
    23941 attttccaag cttacaactt gcttccttat ttatcggctc tagacaacgt catagcagca
    24001 atggaaatca ctaagaccaa gcaagagaat tatcgacaag ttgctttaga tcgactggct
    24061 cgtgtaggaa ttgatgaaat attagcaaaa aaacaggtga ccaaactttc gggaggtcag
    24121 cagcagcgag tcgctatcgt tcgtgctatc tgctgtgaac atcaactaat cgtagcggat
    24181 gagcctactg gaaatctaga tgaaacaact tcacaagata tcgtcaaact tttccaagaa
    24241 atcgcccatg aacaaaatcg ctgtattatc atcgtgactc atgagattga agtagcaaaa
    24301 agctgtgatg aagtctttga actaaaaaat aaaaaatttc aaaaaatcga agtttaaaaa
    24361 acaggataat gatcaaataa aaaatccgaa ccatatctgt ctcgcagata tggtttggat
    24421 tttttatttg cttgattcaa ttagtaataa gtggttttta ttttttttcg tcttttcgag
    24481 aaaacttgtc tttgacttcg tcgcctaaat ttcgagcttt ttctttgatg tcagcaccta
    24541 gtgattgtgc tttcccttct gtttctttgc tcttgtcgtc tgttgctttg ccgtatgctt
    24601 cttttccttc accgactact ttatctttca tatctttaga acgtcctttt aaatctgcca
    24661 ttgtgcttcc tcctcttagt ttgtttattg atctaccttc agggtaacat caacaacaga
    24721 tacagacaaa cagaacgctc gttttctaaa aaagatagtt agagctgttg attaaaaact
    24781 tttttcgaaa gtcccccata ctttgacttc tttttcttgg accattattt ctcctttagc
    24841 gataactgta tcaatatcaa gcgtttcttt atccaagata cacagatctg catcagcacc
    24901 aatttcgatt tttccttttt tatccaattt caatatacgt gctggattac tggttatagc
    24961 tcgtaaggcg atttccaaag ggatactttc tttttgcaca gcttctttga tccctactag
    25021 caatgccttg gcacttccta ctcctaaccc taggaaatga ttgttttcat caaaataagg
    25081 caagcttcct tgtccatctg aggtcatcgt gaaattatct aaagaaacat cttcctcgat
    25141 caatcgtttc agtgctttgc tgaagcgaac ttcaccatct gtcttctccc aaaaatcagg
    25201 atcttcgcta gcagtgaagt caatcgtgcc accacgtttg gcaaatgcca cgcaagcttc
    25261 aaataattct ggtgtgcgat ttgcatgagt aggcaaaaat tgtgtgatcg gaatttctgt
    25321 ttcttctacg attcgtgtca atagctctag ctttcttttt cctccgccta agtggacatt
    25381 gatgatccca gcttttcccg ataacatgcc tcctacacga gcatctgcta ctgcacgagc
    25441 gaactcttca aaacttggct gagaagaacg gtgatcggat actgcgattt ctccgattcc
    25501 gataatttta tcaattgtca aaaagtcttt gatgatagaa tctgttactg tttttaccgg
    25561 caatcggtac gaaccttcgt atacataagt ggagattcct tctgcttcca gacctttcgc
    25621 tttgctgatc aacgcagtca tatctctacc ttctccgtct gttcccaaac aaccgacaac
    25681 tgtcgttaca ccagctgtag tcaattggct caatgtgact tctggcgttc gattttgata
    25741 accgccttct cctcctccac ctaaaatatg gaaatgacag tcaatgaaac ccggggttag
    25801 tacttttccc tcacctgaaa gttcttctac ttccactcct tcgtagccgc cttctagctg
    25861 ttcttctaca gccaaaatct tcccaccggc aatcagtaca tccatttttc ctaagtaatc
    25921 tggtgcaaac acttcaattt gtcgaatgat tttcatacat ttttcctctt tctttaagta
    25981 taactgatga taggatctta aaaaataatc caaacgatag gatctttact cctttgattt
    26041 taccgtaaaa tgacggttct tggagtcctt atctactgtt tggattactt ttttatttac
    26101 aggtctccag tactactgca gacctattgc aatggcaatc atgatgaaaa tagttcctaa
    26161 aacaaacagg aatccttgca tcttgatttg gaatcttgcc cattttgccc attcgatccg
    26221 tgcaacacct agcacaccaa tcaagctggc tgatacgggt gtaaaagcgt ccataaaacc
    26281 tgaaccaagc tgataagcaa gaactgctac ttgtctggat acacctacta aatctgccag
    26341 tggagccatg attggcatag tcaaagctgc ttgtcctgaa tttgatgtaa caaccaagtt
    26401 gaacaaactt tggaagatgt acatcgccca agcaccaatg acagctggaa caccggtcaa
    26461 cgccgtcccg atcccatgca aaatcgtatt caaagctgaa ggaacagatg catcagatcc
    26521 tcccaagaca agaagaatcc ctttggccat acctactacg attgctgtac cagctaaatc
    26581 agctgcacca gattggaaag aagaagcgat gtcattgact ttcattccat ctaatttgaa
    26641 aagaacagca atgattccag caactaatcc catcacaaag aattgagaag cgatttctgg
    26701 aatgtaatag cctttttgag tcacgcccca aacgatccag acaaggacaa ctaacatctc
    26761 taataagatc aatttatgcc caagcatgaa ttttttattt tcatcagatg tctttttgat
    26821 atgagaacgg aaataatcat ctgatttgta agtcaacgaa ctttctggtt ttttacggat
    26881 tttttctgca tatatcatca tataaccagc ggctaatgca gtaacaacta cccacataat
    26941 caatcggaat gtcgcaccag acaacacggg gattccagca atcccttgag ccaccgctac
    27001 gctaaacggg ctcatccaag aggtcgcatt tccgacttga gatgcgacat aagtcacggt
    27061 tactgctacg atcgagtcat atcctaacgc aatgacaaat ggaaccatca ccattgagaa
    27121 tggaattacc tcttctgcca tcccgaatgt agcgccaccg aatgaaaaag caaagaataa
    27181 tagcggtaaa gctaaacgct ccagtccctt agttttactg ataaacgcat agatacctgc
    27241 gtcgatcgct ccggtacgca taataatacc aaaagcacct ccaacaacaa ggatcaatgc
    27301 agcgatccct acagcagatc catacttatc tccagatact agtccttcaa aaacaaaatt
    27361 taagaaacca aagccgccaa aatcatctgt tccccatatt ttggctgttt tatgcaattt
    27421 tttagaagta tcatagatat tttcgccgta ctgatcgtaa agcacatcat ctgtcaagga
    27481 gatttcatct agtttttcct gcgtaagatt tttttctccg tcagcaatga ctttttccaa
    27541 tcctttttcc ggaacatcca gtttttcacg ttctgctgga tgatcttgca gttcttctaa
    27601 ttgatcaaac acatacgact tatccagctc gtaagcataa cggaaggaat cttgacgtaa
    27661 aacagtacga gtacttgttt cgccatttgc atctttgtat tcaatatctt gcgtgctgaa
    27721 ctttcctgct ggaacgacaa aagtcagtat ccatgcaaag atgactacac caaaaataat
    27781 gacatacgta tggggtgtcg ataatttagt gaagtcgcgt ttcggttttc ctgaagaatt
    27841 tgttttcttc aaatttattt cttcctttct tttttcagta attttgatga ataaaaaatg
    27901 gataatcaaa tgaattatac agtaaaaatg acatttccac atgaataatt tattagaaaa
    27961 tcactttttt ctattttgtt tttttctcct atgtatgatt atttttttct ctttccattt
    28021 atattaagta ttttatttct ctgtttttcc ttaaaattct ttttttattt ttagattaga
    28081 gaaaatctcg tcctgttttt ttcattttac aatcattgaa aaattgaatt tcattgcaaa
    28141 aaaaataata aacacttata aatatccatt atctatcctt caatttttgt gtattttatt
    28201 tctattagaa aaaggtatcc tgttggacaa ttttgttata tcaggtaaac ttcattgcaa
    28261 taatgataac aaatgtacta taattacttt gtaaagagtt ttggggaaga ctctttcatc
    28321 aacgtgtatt aagagacaag aaagaatcca tatggattct ttcttgtctc tttttccact
    28381 actttttatt tttctgacac tacatattct tataactcat ttctcataac tgtgaaacaa
    28441 cttataaaaa taacaaactt taaacaaaac aagcttaaaa tcaaagatga tccatcttaa
    28501 aataactaaa acaaaaaaag tagtcgttgt taatcctcat taataatcgt tttctttttt
    28561 tcaaacgctc catttttatg tggaacatta tttttttaag gaactttgtc aacatgtgga
    28621 taactatttt ccacttgtgt cctggactag ctgttttgct gtaaaataca aaacttgctg
    28681 cagcaaaaag atcgttgcaa gagaggctgt tccgcagatc gctggatcta gatttggcaa
    28741 agtcaagact gcatcatgta aattggcgtg gttgtccaaa accaaatcag caaattcaaa
    28801 taatcgcaaa ccactgctat gttgcgattt gatacttcgt gacaaatcaa atccagtaac
    28861 aatgattaat ggatgaccat tttctttgat ccactgagct agttcgatga ttgccgggtt
    28921 tcttccttca ttcgaaagaa gaagaaaaat gtcttctgat ttgacagaaa gctgatcaat
    28981 aattgcctgt cctgcacctt ctagcgtttc atagacacct ccggctggat tttcaatcaa
    29041 tatacttggt acaagatccg gggtttgatc ccaaaattca aatgctacac cacttagtgt
    29101 gcggctagca tatatctgca atctaccacc ttgattaatt tgtttcgcga tccaagtgcc
    29161 agcttgaagc atcagcggct cttctatcct taatttctct tccaattggt gataatagtc
    29221 aaaataacat aaactcattt atctctcccg cctagctata cttgacatga atagaaacag
    29281 ctgcctaatc taaggaagta cataaaaaaa cagtagttag acagtaacac atgtggtctt
    29341 tgctgtttca aacacaaaaa a
//
LOCUS       DAFELK010000032        29106 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFELK010000032
VERSION     DAFELK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.033"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..1029)
                     /locus_tag="LP433_001698"
     CDS             complement(<1..1029)
                     /locus_tag="LP433_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2005864.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLRDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1111..1800)
                     /locus_tag="LP433_001699"
     CDS             complement(1111..1800)
                     /locus_tag="LP433_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL2005865.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1906..2274)
                     /gene="rplL"
                     /locus_tag="LP433_001700"
     CDS             complement(1906..2274)
                     /gene="rplL"
                     /locus_tag="LP433_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBL2005866.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2327..2830)
                     /locus_tag="LP433_001701"
     CDS             complement(2327..2830)
                     /locus_tag="LP433_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBL2005867.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3034..3161)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3240..3929)
                     /gene="rplA"
                     /locus_tag="LP433_001702"
     CDS             complement(3240..3929)
                     /gene="rplA"
                     /locus_tag="LP433_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBL2005868.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4033..4455)
                     /gene="rplK"
                     /locus_tag="LP433_001703"
     CDS             complement(4033..4455)
                     /gene="rplK"
                     /locus_tag="LP433_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBL2005869.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4798..5466
                     /gene="sdaAB"
                     /locus_tag="LP433_001704"
     CDS             4798..5466
                     /gene="sdaAB"
                     /locus_tag="LP433_001704"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBL2005870.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5479..6351
                     /gene="sdaAA"
                     /locus_tag="LP433_001705"
     CDS             5479..6351
                     /gene="sdaAA"
                     /locus_tag="LP433_001705"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBL2005871.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6442..7461)
                     /locus_tag="LP433_001706"
     CDS             complement(6442..7461)
                     /locus_tag="LP433_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL2005872.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7634..8539)
                     /locus_tag="LP433_001707"
     CDS             complement(7634..8539)
                     /locus_tag="LP433_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2005873.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8598..9143)
                     /gene="nusG"
                     /locus_tag="LP433_001708"
     CDS             complement(8598..9143)
                     /gene="nusG"
                     /locus_tag="LP433_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBL2005874.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9244..9414)
                     /gene="secE"
                     /locus_tag="LP433_001709"
     CDS             complement(9244..9414)
                     /gene="secE"
                     /locus_tag="LP433_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBL2005875.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9438..9590)
                     /gene="rpmG"
                     /locus_tag="LP433_001710"
     CDS             complement(9438..9590)
                     /gene="rpmG"
                     /locus_tag="LP433_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL2005876.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9752..10396
                     /locus_tag="LP433_001711"
     CDS             9752..10396
                     /locus_tag="LP433_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2005877.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10452..10955)
                     /locus_tag="LP433_001712"
     CDS             complement(10452..10955)
                     /locus_tag="LP433_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL2005878.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10968..11014)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11552..12517
                     /locus_tag="LP433_001713"
     CDS             11552..12517
                     /locus_tag="LP433_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL2005879.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12616..13788)
                     /locus_tag="LP433_001714"
     CDS             complement(12616..13788)
                     /locus_tag="LP433_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2005880.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13775..14920)
                     /locus_tag="LP433_001715"
     CDS             complement(13775..14920)
                     /locus_tag="LP433_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2005881.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14934..15866)
                     /locus_tag="LP433_001716"
     CDS             complement(14934..15866)
                     /locus_tag="LP433_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005882.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15983..17062
                     /locus_tag="LP433_001717"
     CDS             15983..17062
                     /locus_tag="LP433_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL2005883.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17059..17688
                     /locus_tag="LP433_001718"
     CDS             17059..17688
                     /locus_tag="LP433_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2005884.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17798..18025)
                     /locus_tag="LP433_001719"
     CDS             complement(17798..18025)
                     /locus_tag="LP433_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2005885.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18128..20716)
                     /locus_tag="LP433_001720"
     CDS             complement(18128..20716)
                     /locus_tag="LP433_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBL2005886.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20736..21395)
                     /locus_tag="LP433_001721"
     CDS             complement(20736..21395)
                     /locus_tag="LP433_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2005887.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21444..21947)
                     /gene="trmL"
                     /locus_tag="LP433_001722"
     CDS             complement(21444..21947)
                     /gene="trmL"
                     /locus_tag="LP433_001722"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBL2005888.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22168..23034)
                     /locus_tag="LP433_001723"
     CDS             complement(22168..23034)
                     /locus_tag="LP433_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2005889.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23143..23784
                     /locus_tag="LP433_001724"
     CDS             23143..23784
                     /locus_tag="LP433_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBL2005890.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23846..25207)
                     /gene="mgtE"
                     /locus_tag="LP433_001725"
     CDS             complement(23846..25207)
                     /gene="mgtE"
                     /locus_tag="LP433_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBL2005891.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPLKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25225..26124)
                     /locus_tag="LP433_001726"
     CDS             complement(25225..26124)
                     /locus_tag="LP433_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL2005892.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26126..26923)
                     /locus_tag="LP433_001727"
     CDS             complement(26126..26923)
                     /locus_tag="LP433_001727"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBL2005893.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26901..27605)
                     /locus_tag="LP433_001728"
     CDS             complement(26901..27605)
                     /locus_tag="LP433_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBL2005894.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27736..28311
                     /locus_tag="LP433_001729"
     CDS             27736..28311
                     /locus_tag="LP433_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBL2005895.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28429..29106
                     /locus_tag="LP433_001730"
     CDS             28429..29106
                     /locus_tag="LP433_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL2005896.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8562 a         6167 c         5233 g         9144 t
ORIGIN      
        1 tacagtatta tttcggttgc ttgctgcttc acctagccct tgtactcgtg tttgattggc
       61 gacttgacca aattgattcc cgacgtctaa taaaataata gctaaaagca aaatggccaa
      121 atggcttccg ccaaccaata aagcaataaa gcttattgtt tgcataacaa gtcccatata
      181 cacgattttt ctttcagaat aagaatctgc cagtcgtccc acgataggtg cagcaactgc
      241 tccagacaaa ccaaaaatcg ctaatatccc tgcttcgaat gttccccaat tgtaggcggg
      301 actgctgata taaaaaatca acgtagacca aaagatcgaa aatgttccaa acatgaaaaa
      361 tccactgact gccgcttctc ttaatagacg ttgagaagca actaaatgcg gcaaactttt
      421 aagtgaatca aggtatgaaa cagctgtact actttgctgg acagaacgcg gcattttcca
      481 gtaaagcaga agtgtaagaa ttccgactgc acataaagca aataaataga tcatccgcca
      541 agaaaaaaga ctggcaacaa taccagatac cgtccgagaa agcaaaatcc ccacgagtaa
      601 accgctaagc aatgtaccca tgaccttccc tcttgctttt ggtcccgcta gtaccgcacc
      661 gtaaggaatg atgatttgcg gcacgatcga aagtaatcct attaaaaaag aagcgcatgc
      721 aaataacgta aacgaaggcg caaaaaaagc ggccaacaga gagacggcag ataacgctac
      781 cattcgaatg atcaattttg gacgatccac cacgtccctt aaaggaacta aaaacagtaa
      841 ccctaacgca tagcctaatt gggtcaacat cgtcaatatc ccgactgcac ttgtgctaac
      901 agataaacta gctgctactt ttgttccaat cggctggatg taatacatat tggcaacaac
      961 aacgccacaa gtgattgata atagtaaaat aagcgaagtt gttaaaggtg ttttttcatt
     1021 actcttcatt gatttccccc atttcctatc ttagtttaca acttatggaa aagattggaa
     1081 atagaaaaat acaactattc gccacactta ttatttgtgc ttttgttttc cttgtttttt
     1141 cttgcgatct ttataaatga agacaactaa ccctactagc acagtaacac ttgcaaccaa
     1201 cgtgactgca gttttgttat atccgtgaaa cagagcttct ccaccacacg catacaacac
     1261 agacgaaggg atgactccaa tcacgatcga caatatgatt tgctgtagag gcaatttcat
     1321 cgcatctgca gcaaaattga ccatagaaga tggaataacc ggtatcatat agcctaacat
     1381 tacacctatt tttggatgtt tcatttgtcg gattgcttgc acccaatgat tcgtttcggt
     1441 tttcttatct aaaaatttta agcgatgcat aaggaaaatt gcagtgatgt taccaagagc
     1501 attacccaaa atgttgatga tcgcacctgt cagtggtcca aagctcaaac cagcaatgac
     1561 tccaactact gaagtaggaa tacctggaac agcacacatc accgctgtca atacgatcaa
     1621 gagtatcgat gcaaaagtcc catgcgaacg aatatgtgcg agtagctctg ccttactcgc
     1681 tctcggattt aaaaataatt ggatgtctgt ctgatattct aaatacaacc gatagcccac
     1741 taccagtatc agaatgattc ccaacgagat caacatcaat cggattattt tctttttcat
     1801 atttcctcct gaaaaaaatc tatattcatt aaataatagt ttaacataaa aacaaaaaag
     1861 caccgaaatc caacatagga tctcagtgct tttaaatagt aaaaattatt taacagttac
     1921 agatgcgcca acttcttcaa gtttagcttt caattcttca gcttcttctt tagatacgcc
     1981 ttctttaact ggtgcaggag cgccatcaac tacagcttta gcttctttca agcctaaacc
     2041 agttgcttca cgaactgctt tgataacttt aactttttgg tctccagctg cagttaattc
     2101 tacagtgaat tctgtttgtt cttcagcagc agcagcgcca ccagcagcag ctacagctac
     2161 aggagcagca gcagatacgc caaattcttc ttcaatagct ttaactaggt cgttaagttc
     2221 taggatagtt gcttctttta actcagcaac gatgttttca atgttcaatg ccattataat
     2281 ttcctccgtt taattgttct tttttattta atgctttatg cggcaattaa gctgcatctc
     2341 catcttcttt gtctgccact gctttgacag cgtaagccac gttgcggact ggcgcttgta
     2401 gtacagatag caacatagat agaagtcctt cgcgatttgg caattttgcc aatgctgtga
     2461 tttcttccaa tgaagagact ttaccttcga tgataccgcc tttgatttct aatgcttttg
     2521 cttctttagc aaattcgtcc atgattttcg ctggtgcgac tacatcttcg ttactgaatg
     2581 caacagctgt aggtccagtg aatacttcgt ccatgccttc aaggccagct tttttagctg
     2641 cacgtgaaag aatagaattt ttgataactt tcatttctac gttagcatca cgaagttgtt
     2701 tacgtaaacg tgttacttca tcaactgtta atccgcggta gtcaacgact actactgatg
     2761 cagctgctgt aaatttttcg cttacttcat caacgattgc tgcttttttt gcgataattg
     2821 cttcactcat ttttgagttt cacctcctga attttgatgg aagagttttt tgcactgaaa
     2881 aggcaagtca cttttatagt tactttgctc aaccagtatt attcatcacc tattcacttc
     2941 gttcatagtg attctactcg ctttgctcga aaggaaactc ctttcgcttt gctcaaccag
     3001 tattgttcat catctcttca cttcgttcat agtgattcac aataaaaaac tctatgccac
     3061 cgcagacata gagggactat tgaatatatt caataaacgt cctcggtagg aaattaaggc
     3121 ttgatgccac ctactgtctt cggtacaagt taattattaa cctcaactag cttagcatgc
     3181 taaactagtt gagtcaagaa ttatttttca gttggatcaa tcaacattct aatatttaat
     3241 tagaaagaag cttggtcaac atggatacca ggtccaaatg ttgttgtgat cgttacattt
     3301 ttcatgtatt gacctttagc tgctgatggt ttagctttta gcaatacatc atggattgct
     3361 gcaaagtttt caactaattt ttcatcgtca aatgaaactt ttccgattgg tacatggata
     3421 tttccagctt tgtccacacg gtaagttact ttaccagctt tcacttcgtt tactgctttt
     3481 gttacgtcca ttgtaactgt accagtttta gggtttggca ttaagccttt tggtcctaat
     3541 actcgtccta gacgacctac agtagccatc atatcaggtg ttgcaacaac tacatcaaag
     3601 tcaaaccatc cgttttggat tttttgaacc atgtcgtcgt cacctacgaa atctgcacca
     3661 gctgcttcag cttcttttgc tttgtctcct ttagcaaaaa ctaaaacagt ttgtgtttta
     3721 ccagttccgt ttggtaatac aacagcacca cggatttgtt ggtctgcttt tttagggtct
     3781 acgttcaaac ggtatgcaac ttcaactgtt gcatcaaatt ttgcaatgtt tgtttctttt
     3841 gctaaagcta ctgcttcggc aacaggataa actttacttg aatcaacttt ttttaatgca
     3901 tcttgcattt ttttgctctt tttagccatt ttggttcctc cttgattgtg gttataacgg
     3961 ttgtacctcc cacgtgttct atatctttca atatagagcc aactgagaag ctgctgtctt
     4021 agggtgtata gattattcta cagtgatccc catgcttcgt gcagttcctt caaccatgcg
     4081 cattgctgct tcaacgttag ctgcgtttag gtcttccatt tttaattcag cgatttctct
     4141 tacttgatcg ctagaaactt tcgcaacttt atttttgttt ggttcgcctg aacctttttc
     4201 gattttagct gcttttttca atagaacagc agctggcggt gtttttgtaa cgaatgtgaa
     4261 tgaacggtct tcgtatacag aaataacaac cggaatgatc aaacctgctt gatcagctgt
     4321 acgagcgttg aattcttttg tgaatcccat gatattgata cccgcttgac ctagtgcagg
     4381 acctactggt ggagctggag ttgctttacc tgcaggaatt tgcaatttaa cgattttttc
     4441 tactttcttt gccacgagac atacctcctt aagtccgtga tgtggttaat tggagatgca
     4501 tatttctcct cccacgtttt atctgatctg aaaaaatcca gacaaataat gtgcaaaaca
     4561 atgcacactg gtacagtata gcaaatttat ttgttttttc aagatttttt tctgctattt
     4621 ttacattttg cttgaataaa cgctaaattt attctaaaaa aacaacaatt tttcgttctc
     4681 atttcttctt ttatgttaca cttgcgctag catggttcaa cagatgaaag caaacaataa
     4741 cacggttttt tagacccttg tacaaagatt cctacataac aaaatgaggt ggagaaaatg
     4801 aaagatttaa ggtatagaag tgtctttgat attattggac ctgtgatgat tggtccaagt
     4861 agctctcaca ctgccggagc tgctagaatc gggaaaatca tacgtagtat atttggcgaa
     4921 cagcctgatt ctgtagatat ttatctatat gaatcatttg caaaaaccta tcgggggcac
     4981 ggaacagata ttgcattagt tggcggcctg ttagggatgg aacccgatga tgaacgttta
     5041 gctgattctt tgaaattggc atatgaagcc ggtatggaag tcttgtttgt tcctaagagt
     5101 gaaaaagccg aacatccaaa ctctgtaaag atgcttctaa aaaaaggaac acgaaagctt
     5161 tcagtcactg gcatttcgat cggcggtggc aatatccaga tttctgaatt gaatggattc
     5221 aaaatttctt taagcatggg tactcctacc ttgatcgttg tccaccaaga tgttccaggt
     5281 atgattgcta aagtgactag tatactttct gagaccaata cgaatatcgg cactatgaca
     5341 gtgacacggg aatcaaaagg tgaaaatgcc attatgataa ttgaagtaga tgatcctcaa
     5401 gtagaagaaa cggtaaaaag actcaaacag ctgccaaata tcgacagcgt aaattatttc
     5461 gattaaggag ctaaaaaaat gtttttatcg attgaagaat tagtagatca agcaaaagct
     5521 tatccaagtg tagcagaatt gatgattgca gttgaaatgg aaatgagtgg ccgttcccgt
     5581 agtcacatca tcgagatcat ggaaaaaaac ctctcagtaa tggaacaatc aatcaacgag
     5641 ggaaaagaag gtgttacctc cgtcacagga attaccggtg gtgatgcaaa aaaattagat
     5701 gattatttaa atgaggcaga ctttttaagt ggagaaacaa tcttaaaagc tgtacgcaat
     5761 gctgtagctg ttaatgaagt caatgcaaaa atggggttga tttgtgctac accgactgcc
     5821 ggaagcgcgg gtgttgttcc tggtgtgctg atggctgtcc gagatcggct tgatttgaca
     5881 catgaacagc aattggaatt cttatttacc gctggcgctt tcgggttagt catcgcaaac
     5941 aacgcttcta tcagtggtgc agaaggggga tgtcaagcag aagttggttc tgcaagtgca
     6001 atggcagcag cagctttggt ttgtgcaaaa aatgggactc ctcatcaagc agcacaagca
     6061 gtagccatta cattgaaaaa tatgatggga ctgatttgcg atcccgttgc aggcttagtt
     6121 gaagtcccgt gtgtcaaacg taatgcttta ggctcttctc aagcttttat ctctgctgat
     6181 atggcattag cgggtatcga aagtgtcatt ccgccggatg aagtcgttgc tgcaatgtac
     6241 caagtcggac gtcaaatgcc gtcgattttc aaagaaacag cagaaggtgg cttagctgtt
     6301 acgccaactg ctaaacgact tgcggaagag attttaaata agagggcgtg ataaagctcc
     6361 ttaatttcga gtattaagag attagttatc ttcataacaa aaaacgaaga gaggactaat
     6421 tgcccttctc ttcgtttttt attaatccat caatttcgta ttttttactt catcgatcgt
     6481 ttttgttcct gcaagttgca tcgtgatcga caattctttg ttcaggtgtt caaaaacaga
     6541 tgttactcct tctgccccac ctagattcaa cccataaatc actggtcggc caatcgcaac
     6601 taagtcagca ccacttgcca gagctttgaa gacatgctct cctcgacgga caccagagtc
     6661 gaaaatcact ggtacacgtt tgttgactac ttcggcaatt tttggcaata cttcaaagga
     6721 cgcaggacct ccatctaatt gacgtccacc atgattggat acccagatac catctgcccc
     6781 tgcagagata gcgattactg catcttctgg cgattgtatt ccttttacga taactggaag
     6841 atgggtgatt tctttgattg ttttgatgtc atctggtgtc aagccttgtt ttgcagctgc
     6901 ataaatttct gcgattcctt ttccttcgcc attaccactt gcactttgtt cgctatacgc
     6961 agctaagtta ggcattggta atggaaattg gaattgattg atgacgtctt cttcacggta
     7021 accaccgagc gttgaatctg ccgttaaaat gatagcttta gcccctgctt ctactgcttt
     7081 gttcaaaatg aactcattga atctgtcgtc tttactcata tataattgga aaaactgcgg
     7141 tgcgcctggc gctgcatcgg ctgcgtcttt gattgtcgta tttgcataag tgctgatgga
     7201 aaagattgat ccagcagcag ctactccttt agctgtatca gcttcccctt tttcatgtgc
     7261 caatccttgg gccgctgatg gcgcttggat aatcggtgta tctaattcaa ttccgaaaac
     7321 agatgtatgc aaatcggctg agtcgattcc gcgtaatatc cgtggcatga ttttctttgt
     7381 attaaaagaa gtcgtatttt ctttcatcgt ccactcatct tcagaaccac cgcgaatata
     7441 gccaaaagct cctgcttcca tgcgctcttt tacacgacct tctagttagg caatgtttac
     7501 aatatcgatt ggatgttctt cattacttgt atgataagtc atagtagatc cttctttcat
     7561 cttcttgatt acatataaat catactaaac ttacaaaaag taagcaaaca tttactctca
     7621 gatactttta tcgctattct ttccaaataa atcgacttac aagctgatct acttcttggt
     7681 tttcatgaag catactatga gaggcatttt cacctgtcac tactttttcc tctatttcat
     7741 ttccgcgttg cttcaacaac gcatagaccg ctaatgcact gtttaacggt actgttccat
     7801 cactcaagtc tgtttcatct agttgaccag caatcaagaa aaatcgagtg gttataggaa
     7861 tattaccgat catttgctgg taatcttgat agcggttaga aacgacagca ggcccctttg
     7921 ctaactcatc tgtcagagac tgcgcactat catcgacaaa atcattaaaa ggcgcgccaa
     7981 ttgctgttaa tgtctgaact tgtggcaatg acgtatcctg tccatacgtt cctaaatagc
     8041 gtagtgcact aactcctccc atggaatgcc ccactatgtt gactttatct atgccgtagt
     8101 tttctttcag atacaaaaga caagttttga tccattctgc ttgattccac tcgttatttt
     8161 tattatcttc aaacaatact tggaccatcg gattgtctgc ttttccagac aaatctcctg
     8221 ttgcttgtat ttgtccatct gttcctactg ttaaaaccaa ttcttttact gcttgctgat
     8281 ttttttccaa acgccgcaac atccctttaa aggaattttc tgtcccgctg tagccgtgga
     8341 aaaaaagtgt tggaatagtg gttttttcta tcactttact ggattctgcc gttttttctt
     8401 tatcagaaac ttcagtagta tttatcttcg tcgtctggca accacttaac gcaaacaaac
     8461 tgataaggac taaagctgct gcagttgcac gtttgcataa atttttgatt ggttctgtca
     8521 tacacctctt cctttccata tagaaaaaag aaagacttga aaggccaatc atatgatcga
     8581 catttcaagt ctctttatta atcgatttta tctacttgat cgaaatcaag ttctgtactg
     8641 gtttcacgtc caaacatatc gatgttgact ttcaattttt ctttttctcc gtcaacttct
     8701 gttacttgtc cttctaatcc agcaaatgcg ccttcgatga ttttcacgac ttcgccaact
     8761 tctacttcta gatcattttg tcgcaggctc ataccgatag aacgcaagat atgattgact
     8821 tcttctggaa gtaatggtgc tggtttgctt ccggctccgt gtgaaccaac gaatcctgtc
     8881 acaccaggtg tgttgcggac aacataccat gaagcgtctg tcatgatcat ttcaacaagt
     8941 acgtatcctg ggaatgtttt atgaacgatt tctttttctt tcccattttt gacttcagtt
     9001 tctttttctt caggaacaac gacacggaaa ataaagtcgg ccattttcat actttgcgca
     9061 cgagattcga tatttgcttt tactttgttt tcatatcctg aatatgtatg caagacatac
     9121 cagttttttt caaaagattc cattgaaggc tcctcatttc attgtaaaat aaaaaaacct
     9181 cagtacaccc gaagtttttc tttcgcttca ttatagcact aaaagtacgt tgtggctagc
     9241 gagttatttt aaaatccagc caaataagct ttggatggct gtatccatta cgtaaaacat
     9301 caatccgaaa ataatagaag tttcgatgac tactaacgta tctttacgga gttgttttct
     9361 gcttggccaa gttacttgtt tgatttcatc ttttacgctt tttagaaatt tcatgagaca
     9421 acctcccttg ctactgttta tttcgtttct ttatgtaatg tatattgatt acaatattta
     9481 caaaacttat tgatttccaa acgttcgccg ctttttcctt cactgactga ttttgtgtag
     9541 ttgcgagacc cacaaacgga acaagcgagt gctgcttttt tctttgccat ttacttctgc
     9601 ccccttgctg agaatcagac ttatacttca taacagtatc acgtaacttt ttacttgtca
     9661 atttgtgaaa taaactatct attgttttgg ataaaattat gatatgatta atttgaaatt
     9721 aagctaaaat gagacaattg gaggtatagc gatgctatta aaaacacttg tatataagaa
     9781 aaaagatctg acaaccgtta cagagactag tacattagaa gaagcattaa aaattttaga
     9841 aacttccgga taccgttgtg tgccgatctt agattcttca ggtaatattt tccgtggaaa
     9901 catttacaaa atgcatatct atcgtcataa agcaaatggc ggtgatatga cgcttcctgt
     9961 cactcatctt ttgaaaaacg ctacaaagtt catttacctg gatacttctt tcttcaaagt
    10021 attctttacg atcaaagagc ttccttatat tgctgtcctt gacagtgaaa atcattttta
    10081 tggtattttg acacatagta cgttgcttaa tatgctctct caatcttgga gcgtagaaca
    10141 aggaagctat gtactgacaa ttgcttccac aggaaagcaa ggagatttgg ctgctattgc
    10201 aaaaatcatt tcaaaacaca gcagcattgc cagctgtatt actcttgata tcgaaaaaga
    10261 cgaatacatt cgacgtacat tgatcacgct accggctaac actgaagcga aagtatgtga
    10321 aacgatcgtc aaccacttag agaaaaagaa ttataaagtg gtagaaattg aaaatttgca
    10381 aaaccaagaa gcataatcaa aaagcgaaaa aagaaaacag ctaatctgct ttcttttttc
    10441 gctttttata attagacacg cttttcaaaa tcaagcgcgc gatctaaata atacatcaat
    10501 ggtgctgaaa cagccatgac gataaactca cttaatgcaa gcgtgccata ggttgtccaa
    10561 aatgcttggc cacctgttgg aactaacata taagcaatca gtcccatgct gatggtaaag
    10621 aagatcgtgt tcaatactaa acgcatcttt acatttttca ctttgttttg caataaagct
    10681 gtcaggccta aagaaagcaa tgtttggccg ccaccaaaaa ccacatccat gataccaaaa
    10741 ccaaagaagg cattatagac gatgaccccg cctaaaactc cccaaagcaa tttacggtta
    10801 aagacaacta aatgattcaa actttctgaa atacgaaact ggatcggccc tgaggataca
    10861 ggcgcaacta aaatagttaa cgctagataa agagccatga tgatgccatt tacaacgatt
    10921 acggataacc gttgtctgct tttcgttttt tgcattttct ctcctctttt ctcctagttt
    10981 ttttaacgcg ggatggttga tgaaccgcgg ttatgtgaaa caaacaataa ttataacaga
    11041 cttttcattt atttcaatcc gtcttatctg cttttaaaaa agcaaaagct taaacaatgt
    11101 aaacgtttgc taaaaatcgt gggatatggt ataaagtaag tgtaaggggt cataagaatt
    11161 cccagtaaag cagacgaagt aggatctgca agaacagaat tgttgtgaaa cttaaataaa
    11221 taaaaaagga tgtgggaatt tgagcaacct cttactagag aacggtctag caagcagctg
    11281 aagatctaag tggacatgcc gaaccttgga acttctcctt acgtaagtaa tggatcatgc
    11341 gcttgctagg cttttttgtg tttttcggtc ttcggacctt tttcattttc ctagacttct
    11401 gctataataa ccaagaatta attttgtaac agattttttt gaaaaaacaa gtttctttca
    11461 ttcaaaaaat agaaaaagct tgctaattat tggttaacca gcaaacagga gtattaaaat
    11521 atcttgtttt attgaatagc aggaggaaat catgaaattc cattatcata tattgatcaa
    11581 tccatcggca ggcagcggaa atggctataa agtagcagaa agaattttac cggtattaaa
    11641 aaataagcat attgactata cacttcatta tagtgaatac aaaggacacg atgctgagat
    11701 tgctgaaact ttggcaaaag aaacattgat tccttggata gaagaagaac agaaaacaat
    11761 cgatactttc ccccttttga tcatcgtagg aggtgacggc accttacatc aggtacttga
    11821 tactttctat cagatggaag tagaattccc agttgcttat attccagcag gttctggaaa
    11881 tgattttgct cgaggggcag gccttccaaa aaatcccaaa aaaggacttc agctgatttt
    11941 agcagctcaa tcaccagaaa aagtccacat aatggcttat gaagaaaaaa taagtgaaaa
    12001 aaaaggaata gctgttaata atttcggtat aggattagat gcagctatcg tccatgcgac
    12061 aaatcattct tccacaaaaa agcgattgaa caaatacaac ttaggatcat tttcgtattt
    12121 attctctatt ctccgtgctt tattcactca aaaaggattt ccaattctgg tagatgcagg
    12181 aggaaaacaa ttaagttttt caaacgcatt tttatgtaca gcaacgaagc atcctttttt
    12241 tggcggagga atcgcgattg ttccaactgc tgatgcgtct aaaccagtca ttgattttgt
    12301 cgtggtcgaa cgaatcaatt tctttaaaat cttgtggctc attcttttac ttatacagaa
    12361 aaaacaattg aaatcgaaat atttccatca ctacacaaca aacagattac gtatcgtttc
    12421 aacaacaccg caacatggtc aagaagatgg agaagaaatg gaaaaacgac cttttgatat
    12481 cacaataacc acaactaaac agttgttttg gtgttaataa aagaggtttt gtcagaagct
    12541 acatctggaa caccgtttat tcggaaaaaa ggactgtgac acgacttttg tcacagtcct
    12601 ttttttacta tgcagttaat tctttgccca attgggttgc catcgatagt ttctttcttt
    12661 acccaaaata aattggatca ttgaaaacac cgcagcaaaa gcaactaaga cacaaccatt
    12721 gaaccaaaaa gattctgcaa atgtttgatt gtaactgagt gtttcactga tcaagttatt
    12781 attttgaaca aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca tttctggcaa
    12841 gtattctgct ggtacaaaca ccccaccgat aaagcaactg cctgtgataa aaatatcttt
    12901 gatcccaccg ctggtttctg agttttttac caatgaagtg atacaagccg aaaagctaat
    12961 gatcggcaat aaaaacaaga aagtatttaa aatatgatac cataccgtta tatcccacga
    13021 ggtgtggatc actaacagaa ccattagaag taagaagcca ctgaacaaca gcagcgagta
    13081 actaatcaaa ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg gcgcactctg
    13141 gtttcgttta ctgatctctt tgcgattaaa cgctagattg atgacgctga aaccgctaaa
    13201 aatggataga aacaacccat aagacaagaa attaaaggtt gtgcccgtca acagcttttt
    13261 catccgctga ctatatcccg cacttagctc aacttctcca gtaaccgaga gtgccatttg
    13321 tgtctgttcc atagctgcat cgattgtttt atcttcttct tgaaacagaa tcagtgtttg
    13381 caaaaaggtg ttcacttgct gtgtaacaac tgttttagaa aaggcatctg ggcgactctg
    13441 tatcttgatc gtcgccatct ttcctacttc gacttgttcg gtaaagtctg caggcagatg
    13501 taagataatg tttacacgat taaaataaag agcatcatcg atttcttttt gtgaggttcc
    13561 atccaatgta acgactgttt ccttgtcatt caaatattta cgaaggccat cgactacagg
    13621 cgactcttct tcactaatca aggcgatttt cgcatcttgc agagaggtat tttcaacatc
    13681 aatattttgc gcaaaaaaga atgtggcaac aacagtgata attacaccta tcagtaaatt
    13741 cgatttattt gctttaagca atgtccaaat cgttttataa agcgtcataa cgcacccctc
    13801 tttccatcca agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac catagaagat
    13861 tggtataaaa actagccaaa tcagtgtaga aataaagttt atacaaactt tcgctgatca
    13921 agttgacgag atttaattga ccaacaatcg gaatatgaag atcaatccaa tacttcactt
    13981 gttccgaccc catcatacca gcaaaaaagc tcatcgcaat cgtcactgaa atcaagatgc
    14041 tatccttttg caccagattc atttttggta tcaaattacc aaccaatgta cctaacaaaa
    14101 tcgcacacaa cgaccccaga gcggtaacaa tcatcaacca ttgccaacgt tcaccaaagt
    14161 ctacttgata gataaaacga aagacagcta acataatata aatctctgtc aaaacaatcg
    14221 taaagcttgc tgccaaatta gcgattgaaa ctaacgattg ctttctagga atcaaggaca
    14281 agcgaatacc atttgacgat tgatttgctt gctgatcctg tacattgcgg accccccaca
    14341 tcgtcccgta gagaatcgcc attccaatca gagtgaagaa ataaaaactt ttgaaactca
    14401 tattacgacc tgcatgaact tcttgaaaag atacttcttg ttcaaaaaca gtcatgatgg
    14461 gcgcgagatc aacgttctcc acttctgcca ctttactcga aattatacca atacgctgta
    14521 aaaattgatc catgacgttt ttcatcaacg tctgactcat tcctgcttga cccacatgga
    14581 gcgaaacaga tgaaccatca atgagataaa aaccagccaa atcatctgca tttagctttt
    14641 cattcgcttc tacttccgat agttcctgta cttcaaataa tggtttatca ttgacttcga
    14701 cttgttctaa gactgtggta aaattttccg aaagcgctgt ttgatccgct ttgattacaa
    14761 ttccagtatt aatcgtttca agattgccac cttgatcaat ctcgccaaag gccgccataa
    14821 acatcaatcc taaaagaatt ggaaaggcca atgtccaaaa caacatggat ttatttcgca
    14881 gcagtatttt tgtgcgatat ttataaaaat gccaaaacat tatttcccct cctctagtct
    14941 ctcaaatcct tgccagtaat ctctaaaaag acatcattca aggacgcttc tttggttgct
    15001 atttttccgt aactgatctt ttcttcttgt aagattgtaa gaatcggcaa caatactgta
    15061 tttagttcag tagttgttac ttggagctga ccttttttat aagcgattcc atcagaagct
    15121 attgttcgct gaatcgctga caacacattt tctgggagta atgggatgtc gatcgtcaaa
    15181 cgatccgccg tccgtaccat atcttttaga gattctttgg ttcctttagc aatcacctgt
    15241 ccttgatcca tgatcacgat ctggtcgcaa agaatttcta cttcttccat gtaatgtgtt
    15301 gtatagacaa tggttgctcc ttgtcgattc agctccttga tactttctaa aattttattc
    15361 cgactttggg ggtctacagc tactgtcggc tcatctaaaa aaattaaccg cggcttgtgg
    15421 gcaatcccac atgcgatgtt caaccgacgt ttcaagccac cactaagttc tcctggacga
    15481 aacgaaacat atttttctaa tcccactaat tgaatcacct cttcaatcaa ggctttcctt
    15541 ttctcttttt cggaaacata taaaccgcaa aaataatcga tattttcttg cacacttagt
    15601 tcgtcaaaga ccgcaacgtc ttgaggaacg accccaatca ttgccttgac agcataattt
    15661 tcaggagtca ttgttgtccc gaacaattta atggttcctt tgtcataatt taacaaagaa
    15721 agcatacagt tgatggcagt cgatttccca ctgccgtttg gacctaacag acctaagact
    15781 tctccttctt gtacttgcag atcaaaatga ttcaatgcta caaaatctcc atagcgtttg
    15841 actaatttat caatttcgat aatcatcatg aaaaactcct tccaaatttc ttgttgatct
    15901 gactataata aagtgcaaga aaagaaacta gtgacgattg gctaaaccac acatgacatt
    15961 tgtcacaatg aaggagtctg ctatgcataa atctcggcta ctcaacgaaa ctagctttct
    16021 actggttatc tcattgcttt tgctggtaag tcaaggattc gttgctatgc aagttatcta
    16081 tttattgatc gccgttttat tcactggtgt cagttattta ctgcctacaa agccaaattg
    16141 gattttccaa gttattctat ttcttttatg tgccttttta cctgatcttg tcctgtttct
    16201 gccagcgacg atgcgagtga tcgcccctga agaaagccac cttgattact tgtttttgtt
    16261 aggttttttg ttgatttcga cggttggtaa tcatcccccc atcaaggtcg cctttgtcgt
    16321 aattttgctg tttttttcct tttacttacg aaaaaaagat caacgaacga ccgatcttga
    16381 gaaaaagtac attgtctcca aagatactca ttgggaaaaa caacaagagt tatcggaaca
    16441 aaataaagca ttggccctgt cacaagaaac acaattagcc ttgcaaattg tggaagaacg
    16501 gaaccgaatt gcccgagaca tccatgacaa tgtcggtcat ctgctgtcaa gtgcgatttt
    16561 acaaattggt gcgcttgaaa tgatcaatca agaaccaaaa ctaaaagaac cattagaaaa
    16621 tttaagtgcc accgttcaca ctgggatgga tcggattcgt caaagtgtcc atgacctcca
    16681 tgagacatcg atctcttttc aacactcctt agagtttctg atcgctgatt ttccttcttc
    16741 tgttacgatt gaaggaaact tgtttgaagg attgaatgaa acgcagcaaa actgcttctt
    16801 aatggtcatc aaagaagcct taaccaacag tatcaaacat agtcatgcca aaaccgttgt
    16861 tttacatttt cgaacgttgc cggcctttta tcgcttgcaa atcacgaatg atggcaccag
    16921 cccacaaaaa aattctgctc ccggtattgg tttgaaaacg atgcgtcaac gtgttcaaga
    16981 acaaaaggga caagtccata ttttccaaga aaaccagcaa tttcagttaa cgatcatttt
    17041 accaagggag ggacaccaat gataacagta gtcattattg atgatgatcc atttgtgacg
    17101 aaatcgttac aaaccatttt agaaagcacg aaagagatcc gtgtgttagg cattggtcat
    17161 tgtgccaagg atgcgctagt cttatacgaa acccatcgtc ccgatgtttt gctgacggac
    17221 atccgcatgc ctaaacaaac gggcatcgat gctgccaaag aaattttggc taaatttccc
    17281 aaagccatcc ttttgctttt gacgacattc aaagatgaag aatacatccg cgaagcattt
    17341 tccatcggtg tcaaagggta tttaatcaaa cagaacttgc aagcgattat tccttctgtc
    17401 aaatccgctt ataatggaca ggccgtattt ggtaatgaaa tcatcgagac tttcactcaa
    17461 atgatgaaga ataaaccgac gattgatagt catgcttatg cttcttttag tgaacgtgag
    17521 cttgcaatca tcaaagaagt agctgccggg aaaaacaata aagaaattgc agatgccttg
    17581 tacttgagtg acggcactgt tcgcaattac atcagccaat tactagaaaa gctagattta
    17641 cgggatcgca cgcaattggc tatctatttt tatcagcatt tgcaataagt cttatctaac
    17701 acaaaaaaac ctgaatgatg ctccttcgca tcattcaggt ttttttcaca tcttctattc
    17761 aattgtcccg caaaccattt cctcacgatt gaaagaatca aggattcgca gggctgccag
    17821 gattcgttgg attgttcggc gtgttaggcg gaaaaatagg cgccttgtct aacgtttttt
    17881 ctagttttga ttcttcacga tcgtctcgtt ctacatcagg actttcattc aatttgaatt
    17941 ctttttccat ctcatctaac tttttaaagt cattgccaga ttcttttgct aatttcgcta
    18001 atttatcttc ggtttcttta gccataaagt aacgcccccc ttttgatttc agcttagcat
    18061 atcacactga aaaaacaaaa gaaaacgcta accaacgatc atttttagct atttctcatc
    18121 tttaaaatca agcatttttt gccggtataa aatcgtaggg agaactgttt tccataccaa
    18181 tcatcggatc tactaactgg ttatcgatca cttctgctgt aagaacgaaa tctttagaaa
    18241 cagcaggttc tacctcttct ttcttttctt ctccaacaaa tgaagaaaac agatctggtt
    18301 ccactgtttc cattacttgg tttttcgttt cattcgtccc actgtcatct tctacaggta
    18361 gcttttcttt tacaacccgt ggctcttttg tatagttccc atcttcaaat ggatcatttc
    18421 cgaccaaaga atcttcataa gctgctagtt tggtccggag agtgatattc attttatcat
    18481 tatccatgat ccttgatttc aacgtagtca tccggcttgc tgattcattc gctacacaag
    18541 tgacataggc ttgctcttcc cctaacaaaa tcaacagttc cttactgcga gtcactgccg
    18601 tgtagagcaa attacgctga agcatccgct gatattgatg gaccatgggc aaaataacca
    18661 tcttgaattc actgccttgt gatttatgga ttgagcaaca ataagaaaga gtgattttat
    18721 tccattcgtt tcttttataa gtgacctcat ttgcatcaaa ctggataact aattcatcca
    18781 ctttatcttc agaatctttt gccaagatga tacccgtgat ttctcccata tctccattga
    18841 atacattcaa ttcgggagta ttgactaatt ggaggacttt gtctcctatc cgataaacgg
    18901 tgtcgttcca atgtacttcc ttttttccag gtttccctgg attgaatatc tcctgcatca
    18961 ttttatttaa cgcatcgatc cctgcaggtc cccgatacat tggtgctaat acttggatat
    19021 cttgtgcacg gaatccctta tttttcgctt tttccacaat tttagagatc aagggttcaa
    19081 tttgataagc atcacttcgg aaataggaac gatctttttg attctttgtg aaatcttttg
    19141 gcagacgtcc ttctttgatc tcatgggcaa gaggaataat actagaacca tcaccttgcc
    19201 gataaatctg attgagttcc attttgggaa tttgttcgat ttccaaaaga tcatggagta
    19261 cttgaccagg accgacagag ggaagctgat ctttgtctcc tactaagata acttgcatat
    19321 tcgtcggaat cgctttgaat aatgtgttag ccagccatgt atcgaccata gacatctcat
    19381 caacaatcaa aagtccgcct tctaattctt tcgtactgac tgaaggtgtt ttttcccgtc
    19441 cattcagccc cagaagacga tggatcgtac tggcaggcag acctgtcgtt tcgttcattc
    19501 gtttagctgc tcggccagtt ggtgctgcaa gtagaatagg aaaaatttct tgggtatatt
    19561 ttgaaggatc caattccagt ccgttcaact ctgcaaaaag attgacgatt ccgttgatca
    19621 cagtagtttt ccccgtacct ggtcctcctg ttaaaataaa tagaggggaa cggattgctt
    19681 cagcgatagc ttgttcttgc gaaggtccat actgtatgcc gaatattttt tcgatacgcc
    19741 gaatattctt ctgcacttct ttttcaggat aatggatttc ttttttacga ctgagaaggc
    19801 gctggatcga attaccgatc ccccattcag aaaagtacaa actgttttcg taaagattag
    19861 tctcttcttg ttgtatcttt ccttcttcaa caagttggat aattacagta gcaacctgat
    19921 caggctggat ttcaattggg cgacttgttt ctaaaatacg gatcgtttgc tgaagcaatg
    19981 tctccgccgg tacgtatgta tctcctgttt gaactgcatg ctgaaaaatc tgatgcaaga
    20041 tagctgctcg aattcttctc ggtgaatctg ctgcaatacc gatttgttcg gctagattat
    20101 ctgcacgttt gaacccgatt ccttctatgt cttcgactag ctggtacgga ttttcttcga
    20161 tgatatccaa agactcgttc ttataggcct ggtagatact gaaagctaac tgactaccga
    20221 acccgtaacg attcagtccc atgatcactt gatccatccc gtggtttagc cgaatcgtct
    20281 cagcaagcat ttctcttttt ggcttcgtca aaccggagat ttgttttaat accgaaggat
    20341 cagcaatgat tttttcgata gcatcttctc ccagcaattc tacaattttt tctgctgttt
    20401 tcttcccgat tcctgggaat ttttcgctgg aaagatacgc tacgatccca tttgcagttg
    20461 ttggcttttc ttgctcatat ctttcgagtt taagctgcct tccgtattta ggatgatcca
    20521 ctaattctcc ataaaaacga taagtctcat tttcttgaat atcgccgaaa cttccggtga
    20581 ctacaatctc tttttcacgg taatcagctg tggtttcact gatgtgtacc aaaagcactt
    20641 tgtaaaaatt actaggattt tgaaaaaaaa tcgcggcaac tgtaccaacg aaataaggca
    20701 tttcttctgg ctgcatcgga agccgcctcc ttcttctata gtaaaggttc tggtgctgtt
    20761 tcagttccta aaaaatctgt ttggttccat actttcagtt catatggcaa taatctgcaa
    20821 ggctcttcag tctctaaaat cgtcaaacta ctattgaaca atccacccat ttcacgcaac
    20881 tcacttagct cttttcctgt catccattga atggctgcag ttaaagaagc tccatgtcct
    20941 acgaataaaa gtgggccatc tttatgtcgg gcaaccgcat ctgctacaac agtttcgata
    21001 cgtgtgattg ccgattcaat cgtttctccg tgaaaaggag aaggatcata cagatctaaa
    21061 tgattacgca aattcggcag attatccgga tatttctggt acatttcatc gatcgactga
    21121 ccttctaaag tacccagccc tagttctctt agcttatctg tataaaaaat ctctaccgga
    21181 cgagcaagct ctttgttgat accttctgct gtatcacgtg ctcgctttgc tgtactggaa
    21241 taaattgctt taaaaggaac atattttacc tttttcccaa atgctttgat ttcttcgtaa
    21301 ctttgtggca aaagcggaga atcgccattg ctcccttgaa aacgtctttc ctgattccat
    21361 tgtgtcttcc catgtcgggt aaaatatagt tccatacgca gcaaactcct gtctttcttt
    21421 tattttactc tataataaac tgtctaatcc agcttgtcat tttcatagtg atgcgtcaat
    21481 tctaaattag ggaatccttg ctggcgaagt gcttcataca ctatcattgc agctgtattc
    21541 gataaattca atgagcggac atgctcatca ttcataggga tgcgtaaaca cttttcttcg
    21601 ttttcacgca taaatgtttc tggcaaaccg gttgtttctt ttccaaataa aaagaagtgc
    21661 tcttctccat cagcaaaatt ttcgtcacta tatactttat gggcaaattt tgagatcaaa
    21721 tgtagtttac gattacctaa aaatgttaaa aaagcttcta aattactgtg gtaagtaata
    21781 tttacatcat tccaataatc caaccctgcc cgttttagat gtttgtcatc agttgaaaaa
    21841 cctagtggct cgattaaatg aagcggagta ttcgtggctg cacacgtacg ggcaatattt
    21901 ccagtgtttg cagggattaa tggttcaaat aaaacgatat gattcatcag gatcattcct
    21961 ctcatattta tgttcgtttc tattttctga caatttgatt tttgcataaa aaaaaacgta
    22021 tcaactcggt gtcagtcact gcgagtcgtt acgttagtga agctcttctc actaactttt
    22081 atcagaacag gaacctgata aaaaccaatg aaaaaacaac ttgttgctaa tataacaccc
    22141 tcaacttttt tttgcaacct ctactcatta aaaactgcta gaaaaacgtt ttctcttagt
    22201 tccttttaat aattctatgt caattgtaat cttcttcaaa ggattcttat ataagtctgc
    22261 tttgattcgc tcttctacct gccattctaa aggtgacatg gccaaaagat ctttttgatt
    22321 ttcctctggt atctcaaatt cataggttac acgctgacgt tcagttaatt tcattgcttc
    22381 agcaaacttg gctactacac gttcattgga ataactctgt ttttcaggtt gattcggata
    22441 aaaagcctga cgtagttcct ttaaataatt ttcttgtggc accaccttca acacttctcc
    22501 atcttctgag agtacacgtt ggaattcttg gtaatgagaa ggcgaaaaga tatttaaaac
    22561 cgcgttgaat gtttgatcag caaacggcaa attggtcaaa tcagctacac accaaaatgc
    22621 ttcggcagat tgttctgtag ctgcgtagac tccttctttt gaaatatcaa atccaacagc
    22681 attttgaatc tttttcaatt ttgaaagttc attcaagaag ctaccttctc cgcagccaac
    22741 atctaatagc gagacttctt caggtaaatg ctgcgcaata gtctcaataa cgggctgata
    22801 catgccagat tggatcattc tacgccttgg aacgaacatt ccttgatcgt attctgtttt
    22861 aaccgcatgg gataaaaaat aaagtgttcc ttttttggaa aggtcaaaac ggtgattatt
    22921 tttgcatatc aagccattat cagacttttt tacttcttct tggcaaaccg gacagcggaa
    22981 cagctgatga ttttctgcca aaaactggcg tcctcggtca atttttttta acatagttcc
    23041 ccctcatttc tgttttatct taccgttaga tgctcacttt ggcaactgct aaaaatatga
    23101 tacaatgcct agaagaaagt gaaagataaa ggagaagatt agatgatcaa agaattttgc
    23161 gctgaaaact acacatctat tcctctagca attgctagag gagccgatcg gatcgaattg
    23221 tgtgacaact tagcggtcgg tggcacaacc ccgagtactg gtgtgatcga agaaacgtta
    23281 agttatgctg gggaaaaaga tatccccgta atgacgatta ttcgtcctag agggggcgac
    23341 ttcgtctata acgatatcga attgaaaatc atgcatactg atttgattga agcaaagaaa
    23401 ttagggacgg atggcgtagt atttggttgt cttactcctt caggctggct agacgaagag
    23461 gccttagaac tattgatcga aacagcagaa gggttgcaga tcaccttcca tatggctttt
    23521 gacagtattc ctgaagatcg gcaattcgaa gcaatcgatt ggctggtaga acatggtgtt
    23581 gaccgtatct tgactcatgg cggtcctgct gacaaaacta ttgtagaaaa tttcccacgg
    23641 cttaaagaat tgattgccta tacagatggc cgcttaatca ttttgcctgg tggtggtgtc
    23701 actgcagaga atgcagcaca tgtagctaaa gaattgaacg taagcgaagt acacggaacc
    23761 aaaatcgtgg atcttcagtt ataatcttat aaacaaaaaa acatttgcaa caggcataat
    23821 gcttattgca aatgtttttg tttttttaca taaaatagcc cataaataaa gaagcaatat
    23881 tgaaataaat cagtacactc gtcaaatcgc tcaaagtcgt gataaaggga ccgcttgcta
    23941 ctgctggatc aaatcctaga cgatccatta gcatcgggat taaactacct gcaagattcg
    24001 ccactgtgat tgcaaatagc atagccatcc ctatgacaaa ccccaagata aaattatgtt
    24061 tccaaaaacc tacgattaga aaaatcgtga tccccgtaac agctcctgtg acaacgccgg
    24121 tcaagacttc agccaaaaca agtcgaacaa atccatgatc tttctcatca gaaatcgcaa
    24181 gtcgacgaac agccacagct agcgactggg ttccagcatt accggcagtt cctgtaatca
    24241 gcgaaatgaa gactgctaaa atactcgctt cacttaccaa gtcttcatag tgactgatta
    24301 aagaagcggt cgacatacct aaaaacaaca gagtgatcag ccaaggcaaa cgtcgagacg
    24361 ctgcctttag tggattttca ttaatttctt ccacattgac cccggcaagt cctgaataat
    24421 cgctagcagc ttcatcatca ataacgtcga tgatatcatc gactgtgacg attcctaaca
    24481 aatgatcatc ataatcggta acaggaagag ctaagaagtc ataatctcta aatgtttgtg
    24541 ccacatcttc ttggtcgtcg cctacatgaa ctgaaagcac tcgttcgctc atcagatcag
    24601 aaatcattgc gtcgtcatca ttcacgatta ggtcgcgcag agaaataacc cctactagct
    24661 gaccttcttg attaacgaca tagatgtaat agattgtttc agctacatct gcttcgttct
    24721 tcagcacgta catcgcagag cgaacagttt gattggctac gatcgaaaca aattcagttg
    24781 tcatgatcgc gccagccgtt tcatcctcgt aatggagaag ttccttgatt tcactggcat
    24841 cgtctgccga catcaaactt aaatatttag caatttgctt tttatccagc gtattaagca
    24901 agtcaacagc attatctgta tacatctcag aaagcatatc agctgcatag ctaggacgca
    24961 tttcatctag gtattctttc atatgttcgt tgtcttcttc aatcacatcg aacatatccg
    25021 ctaattcttt aggcgacaga taggaataga tcagctgcct gttctcttct gtaagagatt
    25081 ggtagaattg cccctgctca tagatatgca tctctaaaaa actgtttctg aatgcctgaa
    25141 tattattttc ccttaaatct tgagtcaact gggcaaatct ttcctctaat tcttgatttt
    25201 catccaaacc aatctcacct cgccttattc ttcaaaccgt ctcacaactg cctccatgtc
    25261 tgcggctaaa ggctgcttga actccagcaa ctcttctgta aatggatggt aaaaacgcag
    25321 atcataacaa tgaagggctt gtctttttat tcccagatcc attcgcccgc catacatatc
    25381 atcaccgagc agggcacagc caattgcgga aaaatgaact cttatttgat gtgtccttcc
    25441 tgtatgcagc tggatatcaa ctaacgcgat ttctgttagt cgcttctcta tccagtactc
    25501 agtctgtgcc gaacgtcctt catcagagac cattcgcttc aatagcgaag aataatctcg
    25561 ggcgatcggc aaatcgatat gtccatgtgc cgataaatct gaaagccttc cactgactaa
    25621 ggcctgatat tttttcacaa acttcttttc acgaagttgc atatctaatt ttgcgtgcgc
    25681 aaatccatgc tttgcaaaaa gcatcaagcc agatgtatcc cgatctagtc gcgtcaccac
    25741 atggattact tggttttcgt aaccttgttt tttataataa gcctttacac gattagccat
    25801 tgtcccattt ggatggtatt gggcaggaat agacgaaacg cctgctggtt tatttactac
    25861 cagaacgtgt tcatcttcat acacgatatc gatcggtgtt tcatccaaaa gtacggtttc
    25921 atgttctcct tcagcaggaa tcacaatggt taccttatca tccttagcta gagaaaacaa
    25981 gacattttct acttgatcat taactttgat ttgaccgcct tgaaatttta ttttcgctaa
    26041 cagacccttt gagatccctt tttcttttaa aaaatatttt acttgctgag aatgatcttt
    26101 ctcataatcc catgtaaact gcatatcaat cctcactaat aaaggcatct ttcacacgat
    26161 gccaaaaatg catatgtcga taagaagcaa aatggatccg ttcttctgct attcgataat
    26221 aaattgagcg gatatttgct tttgcgacat tcaattgatc aaccgttaca agataatctt
    26281 ctgtattttc caattttatt tctagccatt catcatgggc aatcacgatc ggagaaccca
    26341 aagtacgaaa cactcgatta ttcagtgaag caatctctgc caactgaaag gcattgatac
    26401 taggatggat cacagcaccg ccgacacttt tattatatgc tgtcgaacca gtaggcgtag
    26461 aaatcgtcaa tccatctcct ctaaaacttt caaacagctc gtttttgatg tatacatcgg
    26521 ctaccatcgt acgattggcc cgtttaatcg ttgattcatt cagtgctaaa aaatgctggt
    26581 ccggtgtttc atccaaataa ctgatccgaa catccagcaa gggataacta acactttgtt
    26641 cccggttcgt tcgtaagctg tctactagtt cttccagctc gtaatcccgc caatccgtgt
    26701 aaaaccctaa atgacctgta tgcacgccca agaaacgcac atcattcaga caatgactgt
    26761 agtgatggaa cgccgacaat aatgtgccgt ctccgccgac tgagatgacc aattctggct
    26821 catgatcatc tcgttgaatc cctgcttgtt ctaaaagtgc gttcaaacgt tctgtcactt
    26881 ctatagtctt tgcttcttta ttatgaacga tcgctacttt catcccctgc ctcctctctt
    26941 tcgctttctt tcttcaaaag cgttcgatag tagacatcat ctgattttcc tcttccatgg
    27001 gagaataacc gctgtgcttc ttggatttct tcacggatac tggacatctc ttcatccaac
    27061 tgataggcag cttctgccgc acgctgaagt cgttcactca tttcttctgg aaaaacgcct
    27121 tgatatttat aattcagcga atgctcaatc gttgcccaga aattcatcgc aagagtccga
    27181 atctggattt ccgccaaaat tttcttctca ccgctgatca gctgtacagg atactcgatc
    27241 accagatgat aagaacggta gccacttgct tttttatttg tgatgtaatc tcgttcttgg
    27301 agaactttca tgtcttttct tttacggatg atctcaacaa cttgatggat atcttctaca
    27361 aactgacaca tgatccttaa cccggcaata tcagacattt cttcttctaa acgtcccatt
    27421 ggaatatgcc gtaattgtga ttttgttaca atactatcga ctggcttgac tctcccagtg
    27481 acaaattcaa tcgggacatg tcgattttgt tcacggaact gtttgcggat cccccgcagt
    27541 ttcactttca attctgatac agtttgttca tatggtgcta aaaatgcttc ccaatctcgt
    27601 tccatagctg atacctctac ttcattaaca ttcattgttt attctaccat atatgcaaag
    27661 ttttttcgta ctcttgattt atgcattgac caaaaaaaga aaattaggca aaatagacaa
    27721 aaaggagtcg atcaaatgac acaaatgctt gaaatcgaat ataaatctat gctgacaaag
    27781 caagagtacg agatattcat cgctcactat caattaacag ataaagattt ccgtgtacag
    27841 actaatattt atttcgatac cgttgatgaa cagctgaaga aacaaaattg tggcctacgg
    27901 atccgtttcg ttggtcatca agctgaatat acattaaaaa cacctgctga aaaagggcgt
    27961 ctcgaaacaa cggatacctt tataacagaa gaagcagaag catttatctt cgaaaaacgt
    28021 ctgcctcgtt caggcgcagt ttttcaaaaa ctttctgatt tgaatatcga tcctgcttca
    28081 ttaatccaaa ccggaaagct tacaacaaaa cgagctgaat tccctattga agaaggactt
    28141 ttagctattg atgaaagctg gggagacaat ctacacgatt ttgaactgga actagaggta
    28201 ggggatgcat ctgtgggaaa aattgctttt ataaattttt taaaacgttt ttctttacct
    28261 tatcgtcctg ctaagaacaa gatccaacgt atgcttgaag ctaaaaatta gaaacctttc
    28321 attttcacaa ggcacttgag ttcatttttt tacttttttc tgttaagtta taggatgtga
    28381 aagaatctag tcactagttg tatagaatct attttggggg agattcatat gatcgaaatc
    28441 tatttatttg ttaatccttt aggggaatac tgtttcgaaa tggaacaaca gttattacaa
    28501 tttatcgaag aagagtacgg gacaccatca aaagaaaaga tgcaatttcg ctttcttcct
    28561 ttggtcaatt tgcagacaat tggggatgtc atgcaacaaa aaggaatttc tcagaacaat
    28621 cttgaggaac gtaatcactt attctcaatg acttattctg cagcattgga ctgcaaagcg
    28681 gcgcagtttc aaggaaagaa aaaaggccgc cgttttttga tcaaattgca agaagcagtc
    28741 ggctgtaatg acataccata ttctcaagaa cttgctgaat ccatatttga agaaatcggc
    28801 ggcgatttga atatgtttaa agaagatcgt cagtctgact tcgttaaaga agtattcttt
    28861 tctgatcaaa aaattgctcg ggaaatgggc atcacaaaac acccttctgc agtcgtttac
    28921 aattatgcct gcgaccgtga ttttggtgtt ttagtagaag taaaaggtac aagtagcctt
    28981 tggagaatca cagagctgtg taaaacaaca gataactcat atcaagtttt taatggtgaa
    29041 catttacata caaatgattc tcagttccat tcaagaacta gccatttaca cttgctttct
    29101 aattaa
//
LOCUS       DAFELK010000033        28115 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFELK010000033
VERSION     DAFELK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28115
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.034"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            88..2478
                     /locus_tag="LP433_001731"
     CDS             88..2478
                     /locus_tag="LP433_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBL2005897.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     KFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGAFKQEGITVKDDGQTFEYTATNTLKKGVVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGISVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDRNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            2527..4362
                     /locus_tag="LP433_001732"
     CDS             2527..4362
                     /locus_tag="LP433_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2005898.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANRTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            4431..5294
                     /locus_tag="LP433_001733"
     CDS             4431..5294
                     /locus_tag="LP433_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2005899.1"
                     /translation="MSMKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNS
                     YKEKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     DNSHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKI
                     VAKRRGMKNEE"
     gene            5284..6393
                     /locus_tag="LP433_001734"
     CDS             5284..6393
                     /locus_tag="LP433_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2005900.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKPETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVLGALASLKVLILLIKEFRKA"
     gene            6732..7532
                     /locus_tag="LP433_001735"
     CDS             6732..7532
                     /locus_tag="LP433_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005901.1"
                     /translation="MVEISKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLMGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYADDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            7620..8426
                     /locus_tag="LP433_001736"
     CDS             7620..8426
                     /locus_tag="LP433_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005902.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQFAEEKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            8658..9527
                     /locus_tag="LP433_001737"
     CDS             8658..9527
                     /locus_tag="LP433_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBL2005903.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAINSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            9547..9894
                     /locus_tag="LP433_001738"
     CDS             9547..9894
                     /locus_tag="LP433_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005904.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            9907..11169
                     /locus_tag="LP433_001739"
     CDS             9907..11169
                     /locus_tag="LP433_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005905.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            11249..12625
                     /locus_tag="LP433_001740"
     CDS             11249..12625
                     /locus_tag="LP433_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBL2005906.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMIIKLVNGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANSSSKEPSIEKKSTFALKLEKNKEEKEKQGAKTLEKLQAEKLEKVLKALDK
                     ADSEPQTSNNTNNEQPISSKTKPKTTDPKVSVNVTITTDKSEKKQVNGTTSPIMQKML
                     KAKKQVHK"
     gene            12622..13251
                     /locus_tag="LP433_001741"
     CDS             12622..13251
                     /locus_tag="LP433_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005907.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRTKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            13270..13749
                     /locus_tag="LP433_001742"
     CDS             13270..13749
                     /locus_tag="LP433_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005908.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            14251..14304
                     /locus_tag="LP433_001743"
                     /pseudo
     CDS             14251..14304
                     /locus_tag="LP433_001743"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            14308..14907
                     /locus_tag="LP433_001744"
     CDS             14308..14907
                     /locus_tag="LP433_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBL2005909.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            14923..15399
                     /locus_tag="LP433_001745"
     CDS             14923..15399
                     /locus_tag="LP433_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005910.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSEDSKSMRDLLITYLNEHEFEQTKVKKKNKK"
     gene            15416..16318
                     /locus_tag="LP433_001746"
     CDS             15416..16318
                     /locus_tag="LP433_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005911.1"
                     /translation="MLFTLLGYLCLVLAFFGAIAIFVGQFQENNPIMRNIGIGIVIIS
                     LIVFGATKIFGSNDQQFGISGVDNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDDK
                     KASDDVLATIKPSQSQFEVFYTVKENNPVRKLTLVFNVDGEEYYKDVKINKASTKKIV
                     ESAKKEVATEESTTESSSTVEVELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQRINVTLFNAVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGSDLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            16391..16585
                     /locus_tag="LP433_001747"
     CDS             16391..16585
                     /locus_tag="LP433_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005912.1"
                     /translation="MVVNKEKVRKYVTLKIASVEYLEKRAKEEEKTRGKKVTVSELLE
                     ELIESDQTIRRAFTNRSVKS"
     gene            16690..17118
                     /locus_tag="LP433_001748"
     CDS             16690..17118
                     /locus_tag="LP433_001748"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005913.1"
                     /translation="MIIQKFDWKMKLGISLVILGFIIFLGIKAQKNQSTFETMSSQII
                     EECSKIYYCENKTEESNGFYYIDQPHDVVIKMESHEVNEWIQRSTNVSKKLERYSQTF
                     LSKVIFSNCKNEETSQRVASSLENLKFSVSKKEKFVDLRK"
     gene            17353..17940
                     /locus_tag="LP433_001749"
     CDS             17353..17940
                     /locus_tag="LP433_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005914.1"
                     /translation="MENNNDIRYFSIGERVTTVSELSKDYRDKEGTIISLKKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVFPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            17940..18836
                     /locus_tag="LP433_001750"
     CDS             17940..18836
                     /locus_tag="LP433_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBL2005915.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNADATNDVAEKRISTYYDKKYLDY
                     LKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLDN
                     LVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGDI
                     WEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVMN
                     APMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVVG
                     LIAFKYNTFEKSKTNVRLQEMG"
     gene            18836..19750
                     /locus_tag="LP433_001751"
     CDS             18836..19750
                     /locus_tag="LP433_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005916.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPANSGIGIVLKAIDEEEIEDFIPAEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCEGYEVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     DARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNASNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKEAE"
     gene            19802..20017
                     /locus_tag="LP433_001752"
     CDS             19802..20017
                     /locus_tag="LP433_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005917.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLQQFWLNNFSYKDFIKEKANRLY"
     gene            20207..20461
                     /locus_tag="LP433_001753"
     CDS             20207..20461
                     /locus_tag="LP433_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005918.1"
                     /translation="MKKEELIDMFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLISDDVNFAHDVVGIQNHIDRENKRMGDGFLPRYSSL"
     gene            20640..21689
                     /locus_tag="LP433_001754"
     CDS             20640..21689
                     /locus_tag="LP433_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL2005919.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGSPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     APNPTPAPAPSNEKVLNVPVIWQGNTMLCEGASLLEGLHYKGVATNQNLTSFVNYMPR
                     ANDNNPYHGYSGEWRYNVNGTYQGMMPDPVVKWAKNVGGNAVNITGSGTNGIKNEIRN
                     GNPVVTWITYNYASPQFKQMPWGRAVWNGHVVLVDGFKNGAYHVVDPVFGAKWINAST
                     YERAFNVTGMAVAVR"
     gene            21866..22096
                     /locus_tag="LP433_001755"
     CDS             21866..22096
                     /locus_tag="LP433_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005920.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEEEYKENIPENLQGS
                     ERYEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            22099..22356
                     /locus_tag="LP433_001756"
     CDS             22099..22356
                     /locus_tag="LP433_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005921.1"
                     /translation="MINEDFRSEQKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            22573..23448
                     /locus_tag="LP433_001757"
     CDS             22573..23448
                     /locus_tag="LP433_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005922.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            23458..24252
                     /locus_tag="LP433_001758"
     CDS             23458..24252
                     /locus_tag="LP433_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005923.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            24281..25399
                     /locus_tag="LP433_001759"
     CDS             24281..25399
                     /locus_tag="LP433_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005924.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            25432..25752
                     /locus_tag="LP433_001760"
     CDS             25432..25752
                     /locus_tag="LP433_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005925.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            26007..26696
                     /locus_tag="LP433_001761"
     CDS             26007..26696
                     /locus_tag="LP433_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HBL2005926.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            26697..26900
                     /locus_tag="LP433_001762"
     CDS             26697..26900
                     /locus_tag="LP433_001762"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005927.1"
                     /translation="MSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNA
                     YIARLKRFIDKYKENSDKFSKDK"
     gene            26920..>28115
                     /locus_tag="LP433_001763"
     CDS             26920..>28115
                     /locus_tag="LP433_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005928.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQE"
BASE COUNT        10755 a         3822 c         5722 g         7816 t
ORIGIN      
        1 taggaatggg cgcgaaggtc attaccacac cgacatatcg tggctcattt tcttcgccta
       61 actggtataa agaaggagta acgagagatg aagcatgaaa aaacgataat tttaaaatca
      121 aaaataattt attgttttgc gactttagta atggtgttat ctacgcttat aatgcctttt
      181 tcagcaataa gagctgaagc agatgtcaca aaaccgacaa gtgcaaaatt tacagaaact
      241 ggcgtaaaaa cagacggtta tattagggtt aatatgccga atcatccaaa tgaatggatg
      301 atttcaagtc aatttaaaga ttctcatgga aatattggat attgtatgga ttcagaattg
      361 ccatccccaa caggaagtgg agccggaagc ttgaagtaca agggagctgg cagtgatgag
      421 ttctatcgta tgtttaaagg tggttttcca tcaaaaacag caaaggaact gggtgcagga
      481 aatgatacag aagcatggta tgcaacacaa ttagtttcat gggttttagc cggaaacttt
      541 aaagtttcac agattgtatg gtcacatcca aaccataccg ccgcagaaac agctcgtgta
      601 aaaaaagcat ttgaaaaaat ttatgactat gctaagaatg gaaaagatac gcccaacact
      661 gagttttcta tcacagcttc taagacagct gacgaaggaa aatatcacac tttcacatat
      721 aaaacagcat caaataagac tggtaatgcg aagctcactt ttacatcagc aaaaccagct
      781 ggtatgaaga tttatgatgc agatggtaaa gaaattacta acaacactgt gaaattaaat
      841 tcaagtttta ctattaaagt acctgtgact acaccaagtg gtactttgtc atttaaaggt
      901 actgctaatg ttagcacaac caatcctttt acttttgatg gacgaggcgt gtatcaagat
      961 gccgtagtta tgatcactac ttcagaaaca aaggactcta aatctttgag tgctaaatgg
     1021 acaagagctg ttggtcaggt aacagttaag aaagttgatc aagatggaaa tgctttaaaa
     1081 ggagcggagt tcactctaac tgacaataac aatgctaaat ctgttaagac aaccggagat
     1141 gatgggttag ctacgtttga tttgcaacaa ggcttaacat acagcttaga agaaacaaaa
     1201 gttcctgaag gttatcaagg ttcatttaaa aaggatggta ttactgttaa taccgatgga
     1261 caaaaattta gttacactgc tacgaacaca attaaaaaag gtaaagtaaa agttaaaaag
     1321 gttgaccaag atggaaaacc attagctaat gctgaattta ccttgacgga tgattcatcc
     1381 caaacacaag cagaaaaaac agatgaaaac ggacttgcaa gcttcgatat tgtagcaaac
     1441 aagacctaca gccttgaaga gaccggagta ccaactggtt atacaggcgc attcaagcaa
     1501 gaaggaatta ccgttaaaga tgatggacaa acttttgaat atacagctac aaacactttg
     1561 aaaaaaggtg tagtaaaagt tcataaagtc gatcaagatg gaaaaccttt ggcaaatgca
     1621 gagttcactt taaccgatga aaaaggtgca acacaagtag aaaaaacaga tgaaaatgga
     1681 cttgcaagct tcaatattgt agcaaacaag acgtatagtc tagaagaaac cggagtacca
     1741 gtaggttaca caggtgcatt taagcaagag ggtatcagtg ttaaagacga tgggcaaact
     1801 tttgaatata cagctacaaa taatttgaaa aaaggtgtag taaaagttca taaagtcgat
     1861 caagatggaa aacctttagc agatgcagaa ttcaccttaa cggatgaaaa aggtgtaaaa
     1921 gaagttaaaa agacggatgc aactggtctg gctacgttca acattattgc gaacaaaact
     1981 tacaacttag aagaaacaaa agtaccaaca ggttacacag gcgcattcaa acaagaagga
     2041 attaccgtca aagatgatgg acaagtcttt gaatatacag ctaaaaacac tttgaaaaaa
     2101 ggtgtgatca aagttcataa agtcgatgat caagggaaag cattagcaaa cgcagaattc
     2161 actttgacgg acgacaaagg tgtaaaagtt gtacaaaaaa cggacagaaa tggcttggca
     2221 acatttaata ttgttgccaa caaaacgtac aaaatcgaag aaacacaaaa ccctaatggt
     2281 tatacaggga aatggtctaa agaaggcatc accgttgctg acgatggaca aacctttgaa
     2341 tatacagtaa ttaatcacct tgtacctgaa acagtaagaa caggcggaat cggtacatca
     2401 gccttccttc ttgtatttct aattgcagga ttgagtatgg tgctactgta ttatcgagaa
     2461 cagcacaaag caaaataaaa aagtgttaat ggaaaagaag taaatatgaa aaaagaaggc
     2521 tgacgtatga aatcaaaaaa aattttttca aatttaatgc tatttggtac tttgctagga
     2581 gtgggattgg gcgcaagctc aatctcttct agccttggac taggggggca agtagcatat
     2641 gcacaacaaa actataatta tcaaggaact ggaacgattc atatccataa agtaacaaat
     2701 actaatgggg atgggaaccc tgtctcagat attgataaca aagggaaaga aatagcttta
     2761 ccaaatggtg taaaacctct tgaaggcgtt gagttctctt atgtgaaact tactaaagat
     2821 gaagctaaat ccttgggatg gacggatagt gatactacaa aaggtcaaca tattgatgat
     2881 gctaaagcac gattattact aaacaaaaaa tacagtgaag taagtagaat gaagactgat
     2941 tcacaaggga atatagacat acctatacaa gtaaatacag acgatttaac agataacttg
     3001 tatttgattg ttgaaacagg aacagtcaaa ggtgtagttg aagaagcgta tcctatgatt
     3061 gttaacgtac ctgaactaaa cggatcagat gatcaatact ttaattatga tgtacatgtc
     3121 tatcctaaaa actatttcca attaaactca gcagagcttg ataaaaaaga cgaagatgga
     3181 aaggctcttg ccggaactgt ttttgaattg cgaaaagatg atggatctga tcaggttgtt
     3241 ggaacttata aaacagacag cacaggtaaa ttaactgtgg atggtttgga attaggtgac
     3301 tattatttcc tagaaaccga tttgggaaca gatgctaata gaacaaccta tttactagat
     3361 ggtaaaaaat tcaaatttag cgttaaacgt ggggagactg ctaaagtagt tcttgatgtt
     3421 accaactaca aacgacctgt aattactaag gtaattgata aagaaaccgt tgatactggc
     3481 gaagatgttc aatatacatt gaaaccatca attcctggta atattggtaa ttacgaaaaa
     3541 tatgttgtca aagatgttct aggtgcagag ttaacttatg attcatcaga agtgatcgaa
     3601 ggaatgactt tagatactga ttacagtatc gaacgtgacg gacaaacgac aaactatgtc
     3661 tttactgaat caggtatgga taagcttcag aaacaatttg atgcagggga tcgcttcttt
     3721 acaattttga tgaacgctca tactaatagt aaagctaaaa tggatacacc acttaagaat
     3781 gatgtttcaa cgatctacaa caatggatat gaacccgaag acgaaacacc agttgatcac
     3841 gcttatacaa tcattggtga tcaccaattc attaaaacag acggagatac aagcaaagca
     3901 ttgagtggag caaaatttgt agtgaagaac aaaattgatc cgaataaagt tacttaccta
     3961 aaacaagatc caacaacgaa agctgttact tggattgcag ataaatctaa agctactgaa
     4021 ttcgtttccg gatcagacgg taagttccaa attgaaggtt tgcaatatac ctatgatgta
     4081 gattttgata aacaaggtaa tccaacaatc acagataaaa aaatcaatga ttatgctctt
     4141 gaagaagttg ttgctccttc aggatataca ccaactagaa acgatgttcc atttgtggta
     4201 tcgaatgatg atgcttctag cgaagtaaca gacatcaaga accttaaaac acctgaaaca
     4261 gttcgtacag gtggaattgg aacagtagta tttctagtgg ttgcaggtgt ggcaggaaca
     4321 gggctatatg ttgtctacaa acgagaacaa cacaaagctt aatgaaataa aattccctag
     4381 agtgtttttg gctctagggt ttctttttaa aaagtgtgtg aaaagtaggt atgagcatga
     4441 aaaagaagaa tatcaagttg atcatcttaa aaattgggat gttgctatgt ttaggagtag
     4501 gtctatatcc tgtaattact caggcttata cctactacca aactcaacaa acactaaact
     4561 cctataagga aaaatatgat gaagcttctg aaaaggagaa tgaagaagtc ttcaagagat
     4621 attcagaagt taataggaaa cgaaaagaca cagaacaaac ctcagtcacg attcctgaag
     4681 ataataacaa tattccgtca aatggaaatc ttcagaagga taaattaggt gaattagtgg
     4741 gtgaaattct tataccaaag attaatgtgg atttgccaat ttatgatggt gtaaacgatt
     4801 tccaactatc agcaggagca ggaatattaa ccggaactga ttatccaact ggtgggattg
     4861 gaaaccattc tgttatatca gctcattcag gcattcctaa taaaaaatat tttacagatt
     4921 tagagttgct caaacttggt gataaatttt ttattgatat ttcagggaaa aaacttgctt
     4981 atcaagtaga tcggataaaa acaattctac caaccgaatt tgaggatttg cttcctgtgg
     5041 caggaaaaga ttatgtaaca cttatgacat gtacacctgt tggagataat tctcataggt
     5101 tactcgttag aggggttagc ataccttacc aaaaaagtat tgttgagaaa gaaaagaaga
     5161 aagaagattt aaaggtaaag gcgcagatga actggtatcc tatcgtagtt gtaggggttt
     5221 tattaataat agctgtgata gtcattatta aaaaaatagt agcaaagaga cgaggaatga
     5281 aaaatgaaga ataaaatact actttttttg actcttattt gcactttggt tttaacaatt
     5341 tatcctgcaa atcagctcta tcatcaattc aaaacaaaag agaatgtggc ggaaatccaa
     5401 gagaaaattg agaaaaaaca aactccttca aaagaggaag tggcaaaaaa agtcgaacaa
     5461 ataaaatcga acagcggtaa ccaaggatta gacaatactc agaaaacaga taaaggagta
     5521 gacaatactc aggaaacaga cggtggatca tttgatattc gtgaagctga aggaaaggtc
     5581 aatccataca caggagatgt tttttcaaaa aatcaaacga aagattttga accatctacc
     5641 tattcaggag cggttggtta tgtctatatt ccaaaaataa atgtgctaga gcttttgttt
     5701 ctaggcgctt cacaggagca tttatataga ggtgtggcac aaatgagtgc tactagtcta
     5761 cctttatcag gtaaaggtca tcaaacagta atagcaggtc atcgtggcgg ttatacgtca
     5821 ccacaatttc tttatgttga tcaattagta gccggagacc acatttatat agattatctt
     5881 ggtgaaaaag cagtttatac ggttttccga acagacgtta ttagaaatta cggtcagaat
     5941 tcaacactga ctgatattcc tgatttagat atgttaacac tttatacttg tcatccatat
     6001 cctcagaact acgatcgttt attagttaga agtctaagag atgaaaaagc aaaatacatc
     6061 acgccacaag taacagttgg caataccgca tacgctgatg ccattgatag tgaatccgtt
     6121 tcagataagc cagaaactgt tacatcttct aatgatttat ttgaggatgt tgatcgtgcc
     6181 aacaaggaat tagatggaaa taatgatctt aatattccgg aacaaggtag cgtagagatg
     6241 caagacagaa cgtttgctga aaaggcaagt tcaatattta caggaattac caataaacat
     6301 cagaaaatgc ttttagtcat ttggactgta ttaggagcat tagcaagtct aaaggttctt
     6361 attcttttaa tcaaagagtt tagaaaagca taatgaagat tataaaaatt gatagagtac
     6421 agtaaaaagg gattgatact attattgatc tcttttttat tttgaataga gctagattca
     6481 cttttaaata aaataaaaac tgatcttaat tccaaagaaa aagtcaagaa aaaaatacaa
     6541 caaatttttt tatcagaata tttatcagaa tattattaga aaagataaac tcaaaagctt
     6601 aatttaatag ggttattggt tgtatttaga aataatgtat ggaaaagcta taaagcaata
     6661 gataagatgt agaaaatctt atttgtgaat gaaaaacaag tcatcgtaaa atattaatag
     6721 gaggtgtagt aatggtggaa atatcaaaaa cagctttaga ctcattagct aaactattta
     6781 gtagcaggtt tgatggtgca gaatttgttg aatatctaag ccaaaacgaa agtggaaaaa
     6841 ctctgatcga aacactgaaa aaagactatt tgaatgaaaa tgactttccg acatggacga
     6901 atattgaaga tgctacatgg gatgtagtgt gtacgatata ttctccttgg gtaacgattg
     6961 ctgattttgt tttagataaa attggagggg atacataccc tgatgccaaa tctcttgcta
     7021 caagtgactt taaaacgttc tatggttatc taatgggtct aataggcaat ggaatagatt
     7081 tgaaagttac gccaaaacaa acacctgaag aaattgaaaa agaaaaagga gaggttcaaa
     7141 tggcttatgc agatgacaga gaaaaagtaa aattattgga aggtaaatta tctgaagaag
     7201 aacttggaaa aatggtgcaa gaaatcaatg aagacagcaa ctattttcct gaattgaagg
     7261 tatatcaaaa cgacgaagat ttctttaatg aaatgtttag taatagtcca tgggaagcag
     7321 tgagtaaaac aaatttagga gaatggaact ttcaagatga tctagttgca tttagcaatg
     7381 atgggtattt acgatcatat tcagaaagtg agtatagagc tgaattaaaa acgtatgaaa
     7441 cggatattct gatgagctat ttaaatctat tagagagtgg tcagggagag ttaagagata
     7501 aagttgaaga actattaaaa gaagagctat agggattatt tcaacataaa cacaagcaga
     7561 aaactaccaa acaaaacgta ccatgcaaaa agccggttaa accggctttt tgctctatta
     7621 tgagaggaga tcaaaccatg agtgcaacaa ccgatatggc tttagaagca gtaataaaag
     7681 ataatacagg aaatgtcgaa aatgtagaag actttagcga tattgcaatc aatctttcag
     7741 catggatttc agctgtagga gaagaaaata tcgaatttga gatcaagaat atggatgact
     7801 taaaagcaaa atttcctttt atcgcatcga aactaagtca atttgccgag gagaaatcgt
     7861 ggaatgaatt agttagtttt tccgaaaaaa tttatgatat tacgcaagaa gatgagtgtg
     7921 tttcatggga aatgaataat caatacaaga aaattgatgc tttcgtcaaa tcacgtatag
     7981 aaggaacagc ttttgagttt gaaggtatag ataccgcaga taattggtta aataaagaat
     8041 cctttattaa aagtatagcg gatgatcttg aaaaacaatg gtctaaggaa gactatgcag
     8101 agtacctaaa aacagaaaga gatacagagg tgaaagaaaa actcactgag gtatgtttgg
     8161 atgaacatat tgatcccaat atcgtaaaac aagaagacta tgaagtggtt attgataaag
     8221 ttcctactga ttttgaggaa gttgtaaagt atatagttga agaagcatta tcgcaatact
     8281 cttcagatga ggaagtggac gaagaaactg ttcgtaccag agtttggcaa ctggtttttg
     8341 atgacaaaga ttataaatat ttgagtgatc aaaactcggt taattggagt gtacgattat
     8401 taattgatca aaatgatatt gaataaaata gagctgaaaa gctctatttt ttttgataaa
     8461 aaaactagct atttttttaa aaataatttg gttcaaaatt tattttttta acttgataat
     8521 tttttgccat ccttttttaa attggctata tatcaaggtt tatagtgggg ataaataaaa
     8581 atacatttga caaaatttac aatatagttt attatatatt tatcttatta tgataacaca
     8641 ataaaaggaa tgatggtatg aaaaagaaga agtttagtcg atcgttgtta ggaattttag
     8701 ttttagttgc ggttggtctt agtggcaagg gttactttca gaataacagc actcaggaac
     8761 atgattttca gatcaaaagt agtgttcagg taggtaataa agcagacagt gaatcaaaag
     8821 aatttttagg gatacgttat gatccaaaca aatatccaaa taatatcgta aacattaatg
     8881 atgggaaata tacactgaca aaagaagacc atgaagcatt atcagaaaaa ggcagtcaaa
     8941 ccttttgggt aaattatgca gatttagatc aacttggaag agcaggagat gttgaagcgt
     9001 tgatcaccta tgatgctata aattctcact catctaaaaa tgtggaacgt ccatctttca
     9061 aaagttctgt ccatattgca ggagaataca aggatggagt atttgatcaa gagagagata
     9121 cttgggtcgg caaagattca aacaatgaaa tcactcagct agaaggatat aaaggttatc
     9181 tctataacaa aagtcattca ttagcatggt cgctaggagg agatatggag gtacacaatt
     9241 taacacttgg aacgagagcg caaaatgttg ggaaaaatga tcagaatgga gggatggctt
     9301 actcagaaac gattgtacgt gatgcaatct ataaaaataa gaatgaaaaa gtattgtata
     9361 aagttgatcc aatttataaa gggaatgaat tggttcctcg tggttctcat gtcgaagctt
     9421 tctcagttaa cgataatgga aaaacggtaa accttaatgt ttatgtattt aacaatcaaa
     9481 aaggaatcaa catcaactat caaaatggta cttgggtaag agattagaaa ttgagaaggt
     9541 gaagaattgg aaacaataag catcaatgga ttagataaat cagttgcaaa tcgaataaaa
     9601 aaaggaaatg gctactatct tctgaagaag ggtaaatatt cagttgctag agagttagaa
     9661 acaatgagta tcgtgtatgt agctaagaat cattttgacg tagaacaggc tatttttgat
     9721 ccagattctg aaatagggaa atgtgttgaa ttatcagaga aaactgttag tacaaaaggg
     9781 gcgatgatca ttgagagaga aatgttagac gaaatcagag taatcattcc taaagatacg
     9841 cagatgtgtg aggacagcat aagtgacgat gaaccaaaat cagaaagaaa ataaggagat
     9901 attcagatga gcgaaaaatc cattgaatta aaggaatata agcgaagcga tggagaaaaa
     9961 tattatcctg tagccagttt ttctaaatca gtatatctgg ttggacgtgc attggtagtt
    10021 ggtgcaattg gcatatatat tttgcattgg gtaacaaagg ttgtacaact gcttgtagat
    10081 accttagtaa gtattcttgt ctcgttaaat gatgttaacg gaacagatga tttaggatta
    10141 aaagaaatgt ttaaagagtt actcaatgcg ttttttccca attatttaag ttattcatat
    10201 aatgtacaaa gcttttttgc aaagctacac ttggtagaca tctctatttt agtattagaa
    10261 gcaggaacgg tattctttgt tggatatttg gttactttga tgttcaggca tcactatgga
    10321 gaacaaagac cattttttga tgatatggaa agtagaaggt tgaaaagaga agctctagaa
    10381 gctatggatg tgaagtatga tccaaacaag attataggag atgaaacgaa caacaaaaaa
    10441 agaaaacgaa acaaaacgca attagaatcc gatgtgctat caacgcttaa aaatatcaaa
    10501 atttctgttc atacaagacg tgatctaagt gtcaatgaag atattcgaga atatatcgta
    10561 aaaatcccgc aaccaaaagg gaagaaagtt agagaaacag ttttacgaca aattcaagat
    10621 ttagggtcga tcctgacaag agcaacaagc ggacgagcca aatttggtga aaaagaagat
    10681 gaagtttcag gcgattattt cattttccga gcatcagtaa atattgaaag agaacgtaag
    10741 gaaagagtaa gtaccaaaaa caaagaaacg gaaagagcaa catcttcaat cgcagtttca
    10801 aattcacaat tttcttttcc aatcaatctc tttgccgata attccaaaaa tatccaaaac
    10861 caaaccgaaa aagctagaaa atatgccgaa actcaaaagc aatctttaga actttatcta
    10921 tcttctgctg acgtacctgc aagtctaaca gatatgcacg ttgggaatac atctattgaa
    10981 tatttgttta ctttatctcg taccagaaaa attcaactaa gctcaatgaa agaagaaatt
    11041 gaaacttact tgcatatatc aggtgtaatc gtgcggatca acgcagggcg tattcaaatt
    11101 actctaccat taggagaaaa tgatcgtatt ccaattgatg taccatcaat gatcaatagc
    11161 gtgttttaaa agacatcaca aatagaaaca gaaaatacaa actaccagtt cacaaacaga
    11221 aaagtaccga gaaaagtgag gaatagaaat ggctatgaaa ttattagaga aagtcaaaaa
    11281 gagagccgaa aaagctgaat ctattttgct agataaagaa cctaatataa agcttaatgg
    11341 aaaattcagt gtcaatatgt tgaacacaaa ggctaaagac ccgacagatg ctatttttgg
    11401 aattaagcct gatggcacaa ttgctcattt ttgcatcagc gaaatgccac acatgttggt
    11461 tgcaggaacg acaggatcag ggaaatcagt attactgaat gaaattcttg ttacagcaat
    11521 gtgtcactca acgcctgatg aattaaaaat aggaattgta gacccaaaaa gggttgaatt
    11581 tggaagatac aaaaaattgc cgttcatgtt ggctgatcca attacagata tggatgaagc
    11641 ttatgatttt tttgaatatc ttgtgatctt gatgcatgaa cgttacaaac tgatggaaaa
    11701 agcagggtta caaaacatca cgctatataa cgaatatgcc gaaaaaaatg gattagatag
    11761 atttccctat gtgatcttat tagttgatga atattcacag ttggttggaa cacataaaga
    11821 agtagaaggt ttgattgttc aattaggaca aatggcaagg gcagcaggta ttcatgttat
    11881 cttagctaca caatctcctc gatcaacagt tgtcactggt attatcaaag ccaattttcc
    11941 gtcacgtgtt tgccttatgg tagcaagtga tttagaaagt aggatcgtat tagatgaagg
    12001 cggtggagaa agcctaagtc caaagggaga tatgattatt aagctcgtta atggaagtat
    12061 ggttagagcg cagggagctt acatcagtaa caaagaaatt gaaacaattt tcaatcacct
    12121 tagaaatact atgccagaac cagaatatgt tgattaccga gcaatcgtag ctgaatctcg
    12181 tggtgagggt ggagaagacg aggattttgg tggaattggt aaagctcctg taagaaaatc
    12241 tgctaaaaga aatttgaaca cacctttagc aaattcatca tctaaagagc catcaattga
    12301 aaagaagagt acgtttgctc taaaacttga aaaaaacaaa gaagaaaaag aaaaacaagg
    12361 agctaaaaca ctagaaaaac ttcaagccga aaaattagaa aaagttttaa aagcattaga
    12421 taaagctgat tctgaaccgc aaacctcaaa caacacgaat aatgaacagc cgatttcatc
    12481 taaaactaaa ccgaaaacta ctgatccgaa agtttcagta aacgtgacca tcacaaccga
    12541 taagtctgag aagaaacaag taaacggaac gacttcacct atcatgcaaa aaatgttgaa
    12601 agccaaaaaa caggtgcata aatgatcatt gtcagttctt ttttgaggtg gcttacgcca
    12661 tataaatata cagatgaagt agttgtgaaa cgaacgaaga aaagagataa aaaagcggta
    12721 ctaactccta aacagatgct tgatcatggc attttagggg tgaaggtttt agaagtgaat
    12781 aaaccgtttg aatcaaatag tgcaagagaa aagttgcttg gagctgaagc cgatgtcgca
    12841 tatttttacc atgacaaaag caagcatcaa atagctatta aattcaatcc aaaatcggca
    12901 tggcggtatc aagcaagaga tgacttgaaa cgtaggaaac ttagaccaat gctctatcca
    12961 gaaggaaaag aagcatttga tagaacccac atcgttccca ttggttttca tggtacagaa
    13021 tcagataacc gcctattagt aggttggaac agcaatcaaa atagagttca gatcaataaa
    13081 tttgagaaga aagtaaggaa attcaacgat cgaaaaacga tcctatggtt tgcagatatt
    13141 tgtaaacagc cggatggaac agcaaagtgg gaagcggtga tatttgacga aaatggtaaa
    13201 aaagtaatgt ctgaaacatg gcatgataaa gctaaatttg tttggcagta gcagtagagg
    13261 tgaaaaagat tgctagaact ttttgaagca aatagaacag gctttaatca aaagttagaa
    13321 gtgggagaaa ctatagaata taaagataaa aactatatta ttatcggaat ctataacacg
    13381 agaattaaca gaataggtga tccacgtata accagtgact tggtttgtca atctgttaac
    13441 tattcacctg atctgacaag caggtataag aaatacgtgt tattagaata tagacacaag
    13501 attactgatg aaattggtgt aaacaacaca cgaaacatat ttaagatcgg aacagtgatt
    13561 ccttatagta acaacgaaga aaaaatattt tatcagattt acggaataga aaagtttgaa
    13621 tatgaacatg tcgatctgct agtgacgtac caaatgcgtt taatagaacc ttggtcacag
    13681 gcagaaattg ataaagcagt aaaattgaac cgattatcaa aatttaacgt attaggaaat
    13741 gccttttaaa aatcgcaata cacaaacaga aaaataccaa aaaattagca atgaacgtag
    13801 gtaagaacat gacaataaat aataataacc ctaaaaaata taatgctctt gtccaatgct
    13861 atatcgaaaa caaaattaca atgcaagaag tcgctgatga attaggcaaa tcaaagagcc
    13921 tagtatcaca cgattttaag cacaatgttt ttccgaaccc gattgagctg aggaaaaaat
    13981 ttcaaaagag agtttatcaa gaaataggta agtggattga tgaagggaat gcaattgacc
    14041 ctttaattga aaaatatcct tttttaaaaa gcaaaaataa aattcaaagg ttaattcgtc
    14101 aaggcgatat tcaagctaaa gaacctgttt tgacaaccaa tgatttggct aaaataaatc
    14161 ttcataaaca aattattgaa gactttgaaa aaaatctttc aacaactgaa attttaaaaa
    14221 aatacaatat tccgagagga aagctaacat cgactctttt tagagaatat ggagaatcgg
    14281 cagttactaa agcaaaggaa gtagcgaatg agagaaaaaa acaaaaatag tagtcgatac
    14341 ctagtagcga ctgtagtttt tgtttgtgta ttgattttcc tgtttgattt tttgcagatt
    14401 ggaaaaagca taattggaaa tacattgagt gcaaaggaaa tggttgcttt aggtggtttg
    14461 tatgaaggac acttgttccc gaatatattc atttctatcg tttctcatat taacttgtac
    14521 catttaattt ctaatttatt gttcttagta gttcttgaag aagcactgaa tgatcagtat
    14581 gagtggttaa cattattgat cgttttaatc atatcaggat ttctaggaag cttagttcct
    14641 tttctgctac acagcaacat cgtaagtatg gggcttagtg gaggtatttt tggatggatt
    14701 gctttatttg cgattgcata catccgtttt gatagcaaga aacatttatt actaagtgtt
    14761 tttgtattat tgataatcgg cattttactg gtatctactt ttgaatcagg cgagacaaac
    14821 gtcttgtcac atgtaatcgg atttgtctgt gggatgatct tgggatttat tctaaagaac
    14881 gtttcattga tcaaacaaaa gaattaaaag ggagtgctaa aaatgccaaa aaaaaaagaa
    14941 aagaaaattc cagtgttttt gtctgtctca gaaatgttat cacttcaaat actgttaaga
    15001 aaaaagattg aaacaataga cgaagaagtt agaaataaaa gggctatgta cgaacaacgt
    15061 gaagcgctaa gagaacgaat ccactatttt gatgatatac acactaaaat ctatgaagca
    15121 cgtacaaatc acgaagacga aagcaaatta ggattagctc aacaacgaat atttgaatgg
    15181 ctgaatacga atactgagca agaaccgtta agagcaatta gtaatctttt tgaatttgga
    15241 acgaagcatt ggtttaacgc tgtagaaaag gatgctgact tacaagaagc gttcgataca
    15301 ctaagcgagg atagcaaatc catgcgagac ttattgatca cttatctaaa tgagcatgaa
    15361 tttgaacaga cgaaagttaa aaagaaaaat aaaaaataga aagttgtgat gtatcatgct
    15421 gtttacctta ttaggttatt tatgtttagt tcttgctttt tttggagcaa ttgctatatt
    15481 tgtcggtcag tttcaagaaa ataatccgat aatgcgtaac ataggcattg gaattgttat
    15541 catatccttg attgtatttg gtgccacaaa gatttttggg agtaatgatc agcagtttgg
    15601 tatttctgga gttgataata gttatgctcc agattcattg ggaagagtag tgatagatgg
    15661 aacgtttgag aatgtaacga gctacaaaaa tgtttcattg acagtgaaag aagatgacaa
    15721 gaaagcatca gatgacgttc tcgctacgat caagccgtct caatcacagt ttgaagtgtt
    15781 ttatacagtc aaagagaata accctgtacg caagctaaca ttagttttta acgttgacgg
    15841 agaagaatac tataaagatg taaaaatcaa taaagcatca acgaaaaaga ttgtcgaatc
    15901 agcgaaaaaa gaagtagcta cagaagaaag tacaactgaa tcaagttcta ctgtcgaagt
    15961 tgaactacca gataaaattg attttgatcc tgaaaaagtc aaatcgtttg aatctgtttc
    16021 tggttctatg gcagatcggt ttaacactga agttttcaaa gctatcaaaa ctgttaaatt
    16081 ggatactgaa aagcaaagga ttaatgttac cttattcaat gcagttgaat ctatggatca
    16141 ggataaaaaa gttacggttg caagagaact agggaaaaga gtaattggat tgtatcgagg
    16201 tacggcaaaa ccagattcag acggttcaga tttgccagtt cacgtagttt atgaagacgg
    16261 taaagttttt ggagactcta cagcaaatga agcactaacg attaaattag ctaaatagcc
    16321 ggaaaattat aataaacaag tggtgtcaca ccaccatcgc ataggtgtga caccttggag
    16381 atgattactg atggtagtaa ataaagaaaa agtaagaaag tatgttactt taaaaatagc
    16441 ttctgttgaa tatttagaaa agcgagctaa agaagaagaa aaaacaagag gtaagaaggt
    16501 aacagtttca gagttgttag aagaattaat tgagagtgac caaacaataa gacgtgcatt
    16561 taccaatagg tctgttaaaa gttagggtga tactatcttt aatttcaacc aaatttctaa
    16621 tatatgatga atagtttcct tgtacaaaat atctaattaa gagataaaag ttaggaggat
    16681 tcattcaaaa tgattatcca aaagtttgac tggaaaatga aattaggaat tagtcttgta
    16741 atattgggat ttattatttt tttggggata aaagcacaaa aaaatcaatc tacttttgaa
    16801 actatgtctt ctcaaattat tgaggaatgt tccaaaattt attattgtga gaacaaaact
    16861 gaagaatcta atggctttta ttatatcgat caaccacatg atgttgttat aaaaatggag
    16921 tcacatgaag taaacgaatg gattcaaaga agtactaatg tatcaaaaaa gttagaaaga
    16981 tattctcaaa cgtttttaag taaagtcatt ttttcaaatt gcaaaaatga agaaacgtct
    17041 caaagagtag ctagttcttt agaaaattta aaattttctg tttcaaaaaa agagaaattt
    17101 gtagatttac gaaaataaac tatcgaaagt agtatgatta tgatcttaaa atatcatctt
    17161 aagagaagaa ttacgattgt ttataggatt tacaaaatga ataagtttga agagtgattt
    17221 ggtcgcagac tagatcactc tttttgtgta aaaaaacttt acacttattt ttgagtgtgt
    17281 taagattttt tatatagagt gacggtttct tgtcagagtg gatgataacc atcaatattg
    17341 gaggaataat aagtggaaaa caataatgat attagatatt ttagcattgg ggaaagagtt
    17401 acaacagtaa gtgaattatc aaaggattat agagataaag aaggaacgat tatttctctt
    17461 aaaaagaatc gaagaggtgt ttggcaatat gttgttgatt taggggatgg cgttacagtt
    17521 gagtgtaaag atagtcaact gatcagaaat gatggcagtc attccattga aaaagcaatt
    17581 cttgtattcc caaaagtatc aagcaagatt atgaatgact ggttgcttgg aaaatttggt
    17641 gagtacaata aaaaagaaat cgcagaagtg atcggcaaat cttatccaac agtattaggg
    17701 tatctaaaaa agataacgaa caaagaagcg aaagttgagg atgttttaac agtaagagaa
    17761 cttcagtcat taatcgaata tcggaataaa caaataacaa atcctgagta ccttaaaaaa
    17821 gaagatggtc tattgaaaca attggaacag gtaaataaaa tccggaaaat gcaaaaggta
    17881 gctcctttaa gcctagataa ctttaaaaaa atctatttga aagagatcga aaaagactaa
    17941 tgtggagtgt cactttaccg tttcaacctg tatctgcacc aagaccaagt gcaagaagga
    18001 atgctgatgc aactaatgac gtagcagaga aaaggatttc aacctattat gataaaaagt
    18061 atctcgatta tttgaaaaaa ataaaaagct ttatcgaaga tcaaggtttg ttagatgatg
    18121 aattttactc gatcgtaaat gatccgatgg gtgcaattat ggaagtggac ttttactatc
    18181 agataccaaa aagctataaa aaagtctata acattatgaa aacgacagcg ccagatttag
    18241 ataatttagt aaaaagtgct atggatggta ttttcaacat ctcagctata cgagatagcc
    18301 atatcacagg gttaattgct tttaaataca atgtggcaaa cgaaggaaaa acagttgtga
    18361 ggatcaagcg atattcagaa tttgagtggg atacttctga aggattgaac ggagatattt
    18421 gggaagccac atttgatttc aaaccagtag caacgccaag accaaagtct aaatttagag
    18481 gaaatgggat tatcacttac tatccaaaag agtataacga ctatttggaa aatatcaaga
    18541 atacgcttaa agagaaagat ttggtaaatg atcaactgaa aaaggtaatg aatgctccta
    18601 tgggggttat agctcagata gattattttt accaagtgag aaaagataag aaaaagcttg
    18661 attcactgat gcgtacttca cagccggata ttgataactt agtcaaagga acattggacg
    18721 gaatttttaa caaggaaatt ggcatcaaag atagcagggt ggtaggttta atagctttta
    18781 aatacaatac ttttgaaaag tcgaaaacaa acgtgcgact acaggagatg ggctgatgaa
    18841 taataacgaa aaaattcttc atgtacttga tagctttgaa acaattcaag aggaactaaa
    18901 gaaatatcga gatgttttgg aacaaagata tgattttgtc aatcagcaaa agagtaatca
    18961 catggatttc attctcaata tgaatgactt gaagaagaaa ttagttgaac gaaaagaaca
    19021 agaaaagttg atcaaagctt actttgaact cggtgaaaaa gaagttaaaa aggcaatgga
    19081 actgaatgaa gatcgcaggg ttttagatca gctgttagaa caattattgg tgatgtttca
    19141 aaaaggacga atagatgagg atttaattga agaagggttg agaaagtatc ctgcaaactc
    19201 aggtatcgga atagtgctga aagcgattga tgaagaagaa attgaagatt tcataccggc
    19261 agaggatttt gaatcggcaa tggaatatat aaaatattac agccaaggga tcactgcttt
    19321 tagagagttt gatcctgaag atgttattca tgacttgaac aacctaaaag aatggtgtga
    19381 aggttatgaa gttgatgatt ccggtttgga ctacttgatc agtattatgg aaatcgaaga
    19441 agagatgccg gataagcctg atccaacaga tattttagaa ttaatccatg atgctagaaa
    19501 tccaattgca tacatttcta gaggatatac tgtattggaa tactataagc cttatatatc
    19561 agcgatgaac catttaagac gtgtattaag ggaaaaacgt gaataccgct cagtgttaaa
    19621 tgcatcgaat agattagaaa aagctgtttc agagctagat gcttattatc gtgaacatta
    19681 cctgcaagca ggtggtatgc caagaaatac gaaagcaaat atcagtaggt atataaaaga
    19741 agctgagtag gcggagttag cccataaaat ggcaaaaggt aacctgaaag aggcgttttg
    19801 aatgaaaagg gatgtttttg aattgtacgt attagaacgt ctagaagacg gcatgatggc
    19861 acaagagata attgatgaaa ttgatgatat gatcagcaga tttggtcaat tggaattgaa
    19921 tgatggaaac aaaaattcgg tagtgctaca acaattttgg ttaaataatt tttcgtataa
    19981 ggattttatc aaagaaaagg caaatagatt gtactgacta aattcacgag gatcagtgat
    20041 gagagcttat tgctaagagc agttaggctc ttttttgttt gtgttaaatt attttatttt
    20101 acaatacaca tttatacaca aaaaatgttg acggatagta cacaaatgtg gtaggatata
    20161 tttgtaagca agttagatta acaagttaaa ggaaggaaga gcagttatga aaaaagaaga
    20221 actaatagat atgtttcaaa ttgttgaacg agcaaataat atgggaatta tgttttttga
    20281 tcgtatttct ttaaagatgg atttaagcgt tgcccaccaa gaatttaatc tacgattaaa
    20341 agctttattg atttctgatg atgttaattt cgctcatgat gttgtaggta tacagaacca
    20401 tatagataga gaaaacaaac gtatgggtga tggattctta ccaagatatt caagtttatg
    20461 atttggcgaa agattcaaga gtatgtgtca ttattgatag gtactcttga attggaaagg
    20521 aggaatgaat ttaagacaac aacgattatg atcttaaaac aatcgtttat gtaattggca
    20581 atcttacgaa taattttcat gcaataatga caataaaaaa tgaaaagggg taaaatcaaa
    20641 tgaaaaaatt tttagtagga attctattca caatggggct agtgctatta tcaccttcag
    20701 tttcagcaga aagctctatt tccatgtatc gtatgtataa tcccaatagc ggagagcatc
    20761 tatacactag aagcgttgga gaaagagaca atctgaaacg ttatggatgg cattacgaag
    20821 gtgtcgcgtg gcaagctcca acaagtggtt ccccagttta tcgcttgtac aacagatata
    20881 acggtgaaca tttttacacc gttgatgccg gagaaagaga taagatttcg cacacaggat
    20941 ggacgtacga aggtgttgcg ttctattcct acaacggagc aaatagagtt cctgtgacac
    21001 gcttgtacaa caaatacgtg aattggcacc attacacgtt agatcaaaat gaaaagaacg
    21061 taattagtaa acaaggttgg aagattgaag gtacgggttg gtatgcaatg ccaaacagcg
    21121 caccaaatcc tacacctgca cctgctccaa gtaatgaaaa agtgttaaat gttcctgtca
    21181 tttggcaagg taatacgatg ttgtgtgaag gtgcttccct gttagaggga ttgcactaca
    21241 aaggagtagc gacaaatcaa aacttaacca gttttgtaaa ctatatgcca agagctaatg
    21301 acaataatcc atatcatggc tattctggcg aatggcgcta caacgtaaat ggtacgtatc
    21361 aaggcatgat gcctgatcca gtagttaaat gggcaaaaaa tgttggtggt aatgccgtta
    21421 atatcactgg ttcaggaacg aatgggatca agaatgaaat tcgcaatggt aatccggttg
    21481 taacttggat tacttataac tatgcttcac ctcaattcaa acaaatgcct tggggacgtg
    21541 cagtctggaa tggacatgtg gttctcgtgg atggcttcaa aaatggtgca taccatgttg
    21601 ttgaccctgt atttggcgca aaatggatca atgcaagcac gtatgagaga gcatttaatg
    21661 tgactggaat ggcggttgct gtacgttaat tgatagaatt aataaataaa tgaaataaga
    21721 gcttaattac tgaaatggta aatgggctct tattttttag aaaaaaactg ttttttgtaa
    21781 tacgaattta taacaaaaaa cgttgaatgt agtacacaaa agtggtatat taaaaccgta
    21841 gagattatgc gaagaggtga ttttgatgaa ccaaagaaga agaaaaaggc tagaagaaat
    21901 aagcgagcga ctatccgagt taaaggatga gttagaagta attcaagaag aagaggaaga
    21961 gtacaaagaa aatatacctg aaaatctaca gggatcagaa agatatgaaa aagcagaaga
    22021 atccgttgat caacttgaag aagctgttga tggtttatcc gacatattag aattgattga
    22081 agatatagct agctagagat gattaatgaa gatttcagga gtgagcaaaa aatgattgat
    22141 atttcactga tagagaagct acttttttca aataagtaca cagccaaaga gttggctaca
    22201 agatggcaaa tatccgaatc agctattaaa gcctatcgtc aaaataaggg aagcgtagga
    22261 tggcgtgatt ggaaaggaat cagcattgga aaagcagaag acataatgaa acgtgaagga
    22321 tttcaagctg acaatgattc taaaaaagtt gaatagttta atagtcgcca agaaaagtac
    22381 caggacgagg ggaaaggtag attacaaagg aaaacacttt taaataaact tcgcaaaagc
    22441 atcaggttat gagtggctag ggctatacga atgtgatgaa aacaaagggc tttaatgtca
    22501 aagaaaacgc aatagggggg gaacaaaatt tttaaaaaag atatttatgt ttggtttaat
    22561 ggaaaaaaat atatgactac taacaaaagg tggtcagagc tagtacaaaa tacagttaaa
    22621 aaagtcatgc cagatggata tcatttcaac tatatacaat gctcacaaac aactgaaagt
    22681 atttattttt caatattaaa tgagaataga ctctattatt tcagggtaag ttcacaccat
    22741 aggaaaaaga gagaagataa tgttacgaca tttttatcgg gaaaatacaa tggcttcaaa
    22801 gagttaagtg aagccattgg tgagtatcta aaaagtaata gatttgtcag aatttctgac
    22861 aaacatatat tgatcttgtt actttatttg aataatagct tcaaattgtt ttggagagac
    22921 gacactttct actatattga gaacggcatg gatatttatt ctggtatcaa cggcatatta
    22981 aaacattata ttaaggcgtt acttcgatat ggggttcttt atcaagaaga tttaagtaac
    23041 caaattaaga ttagtaattc tggaaagtca ttactggcaa aatataaaaa attgctttct
    23101 cctatctaca aaggaataga tatggaagct gtaaattctg aaactttatt taatttagtt
    23161 gttgatgaaa agtttgcgaa tgaatttttt aaaagtaaaa aaattgaaag actaaataac
    23221 ctgtttcctg aaaatgcaat aaaagcttat gtagataata ataaatcacg attatacaac
    23281 tggtttattc ccaaacggtt gcgaggaaaa atcaaaattg gcgatcaagt gaaagtaatt
    23341 aatctaaatc atactaagat cgttaccgta acggagttgt atatagctga aaaagaagat
    23401 attacaaaaa tgaaaccagt tattaaaata ctagataaca aagagtgagt ggaatatatg
    23461 gtagcaaaaa agaatactct aaaagaagct tctgaaaaat atcaagatat gaaaagacga
    23521 ggattaatac caaaggacaa aaaaggtata tggagagaat ttgttaagga agtcagtagt
    23581 gatcgaagtg gcggtgactt tgttggacga tatacagcaa aaggttatag caggcgctta
    23641 aggatcactg ttgaatatgg aacgaatgaa tcagctacag agctgaagca aaggtactta
    23701 gatacacgaa gagaagcttc aaaaaaatat gatgatttca agagcagagg tctaattcct
    23761 aagaagaaaa aggggatttg gcgtgagttt ttcaaagaag aagatagcaa tcggaataag
    23821 ggagacttca ttggacgata cacagcaaaa ggctacacta agaatttagg gatcaaggtt
    23881 gaatacggaa ctggtgaaag ttcatgggaa ttgagaaatc gctatttaaa tacattgtta
    23941 gagaaatata aagcagaatt attggagttg ttcgatgtta atgattttat cgagatggct
    24001 gaaaagtatg gtcatgaaga aggttttatg atcaatgaca ttatggttat tgataatttt
    24061 acggatttat tagcacttgc gaaaaaagca agggatttaa gagaaacgca gatgtatcta
    24121 ttcagaaata aaaacggaag aaaccggaga actgaatcga gtgagattga agattactat
    24181 gatgccttta cacacgatct gggagccttt gtagacgaga taagtggtgt aatgaacaaa
    24241 tatagggtct agaataaaaa agccggagat gagcagataa atgggaaaca atagcatata
    24301 cacacctgaa atgcagaata aaattaaaag acttgtcgga ttagggtgga tgacaagagg
    24361 aaaattagat tcttttagta cgatcaaata tcttttgatg gacatttacc gtcagaacaa
    24421 gcaaacagga atacattttt tgggctatga taagccggaa gatgcacctt tctttgttcc
    24481 aagttcagcc tatagagcca gtacctccgg tagcatgtat aacttggatt tgtttgagga
    24541 aggagcaaag atgatcgaat atgatttcaa cgaagcctat tcgaggatca tgagaaatta
    24601 tcctttgccg tcaaacactt atttgaaagc aaaatataat acagatcaag ctattttgag
    24661 agcgataaat agaccaaaag taagaccgta tgaaaattta aaaacgtata tgttcttttt
    24721 ggttaatttt gaaggaacag ccaaagaagg aacatatgct aatccaaaat cacagtcgat
    24781 gtttgcggat tatggcgaaa atcccaaaac agctaatgag cctatttggt tatcggagat
    24841 tgagctaaca cttatccttg attattatga tattaaagag atggaagtcc tagatagcca
    24901 cacatttttg acgaaaaaag gattactcaa agaatatttt gaaagaatcg agccattaaa
    24961 aactgatcct gatacgttga agctttataa aaatcttaga acgaaagtat ttggtgctat
    25021 cggacaaaaa tcattaagag aaggagaaac aagcaccttc gataaataca gtatgtataa
    25081 tcgagcgtat tcctccatgg tagcaggcgt atttagagat cgtatggtta gatatgaaca
    25141 gaaatacgtt catagcgcat atgggctatt aaaaattcgt actgatggat tgtatttcag
    25201 atccgaagta ccagagtttg aagagctgta taaacttgga gtagttaaga aaaaagttca
    25261 tacaatatcc aaagaagaag tcgaaaaagc tttagaattt aaaaacaaag gatttgaaaa
    25321 taagggctcc tttgggaaat ctaaagatga agttaagggt gttgtgatag acgatgattt
    25381 cgagtttgat tttgactaaa tactctttgg aaaagatggt aggaggtaaa tatgaagaag
    25441 aaaattgtgg aaggaaatgt aggtgttatt attctaaaag attcaactga ctatgctaaa
    25501 tcaatggcac taaaagacga aaaagttgca cgcatggata aagatttagt tgaatttctg
    25561 atggatgata cagaaagatt aaaaggggat cagtttttga gtttaatgaa agacaaaggc
    25621 ttaaacacat atggtttatt tgattataag aaattagcta tagagtgggt aaaagaagga
    25681 gaaatatttt ttattgaaga atgggaaggt actgagaact tagttcttca tcagtatctt
    25741 ttgaaagctt aatctaagta aaacagttct gactagttat gcttgtcaga atttcaaagg
    25801 aagttttcca taaccatcat cattcaaaaa taaaggattt gaaaataagg gttcctttgg
    25861 gaaatctaaa gatgaagtta agggtgttgt gatagacgat gatttcaagt ttgattttga
    25921 ctagattttt ttgcaatgtt taagagtaaa caaggtaaga actaagatca tgaagattga
    25981 gagtaaagaa gatagaggac gaatgtatga gaacacacta tatttattta gaagataaaa
    26041 ttgtagatga aattccggca aaaagtcgag aacaagctag aaaattattt attgaaaaat
    26101 acaaagagat caatggagat agtgaagttc caaaagtggt cgtaacagtt agaaaaaggc
    26161 aaacaaaaaa gagaagtacg tttcatgtca gccctgatat atataatctt atagagcgac
    26221 atagaagtga agataatatt tctatctctc aatatattgc tacagttatt gatgaattga
    26281 tttcaggaaa gtatgactat gcttttgatt ttgagggtga aaaggattac aaaagtgttg
    26341 ctgtctttca atctgatttt gagaagctaa aaaactatgc tggcaggaga aatgttaatt
    26401 ttgcaagact actagaagag ttctactccg aagagttggg agtaggaaat gaatacaaga
    26461 gagaaactta tgcgaaattg tctcataagt tatcccaagc gcttaaagaa gtgacagaag
    26521 ttaaagcgga actagatgct aaacttgaag aagtgaaaaa atatcaaaca gagaggaaga
    26581 acaacatgaa gaatcaagtg gaatttgacg aacagaaaga atttgaaaaa gcaagaaaac
    26641 gctataacaa aattatgaat gaacttagct atgaacactt aacagttcat gaataattga
    26701 gtgagggtac agaaaaatat acgatcgcag atatggttaa tgaagtggaa actcttttag
    26761 cttctttctt tgaaaatggt cacgtaaacg atgaatggcg aaaagaagaa cctaaaaggg
    26821 ttaacgctta tattgctcga ttaaaaaggt ttattgataa atataaggag aatagtgaca
    26881 aattttctaa agataaataa ggagagagtg tgattacatt tgccagaaat cgaaggaata
    26941 ttttcgccaa aaataggtaa aaaacagtta gatttcagca gttttccgag cgtaaataga
    27001 gattataatc taggtgatga ggtacagata ctaaatattg atttcaaaga actagacttc
    27061 gctgttgctg tttccaacaa acccaaggca ttggaacgag tgaaaaaaat ataccaagag
    27121 aatgatcaaa atatcaaaaa tatgatcaaa aagtatagac gagataattc aaaagttgaa
    27181 gacgttttat tcaacggtac ggcaaaacat gatttgaatg tttatatggc attaggagtg
    27241 gctttgtact gtaattcaat taatcagaca gatattttgg ttaatatcgt gaggaatagc
    27301 tatcaaaaaa tattaaaaat aagtagcgaa acaaaccctt attatgcaat gaaatatctt
    27361 ggggataatt tattaaatga taaaaaattg atgcacaaca ctgaagagct gttatctaat
    27421 ttggctgcga ttaactttct attcaaaaca ggttctgaag attattttat agataacgta
    27481 ctaaaaggtg cttacggaac agcattttat ccgctttaca atatgaaaca gcataaagcc
    27541 gaacaaaagg ataacaaact tgaaattaaa aagatgaaag aactattagg tataggattt
    27601 gtaaaaccca attcaaaagt cactattgct tcgttagcaa ctactaacaa tgatgggaaa
    27661 atagtaaatg ggtttgacga ttcagatata gatatattgt caaaatcata tttttctttg
    27721 tatggagatt ttgcagattt gatgggtatt gatagttact tagtcaataa ttttgagatc
    27781 aagggtagcg agctgaatga tattgtgtat ttcgttttaa tctctctata tgcaattgat
    27841 cagaataccg agtaccgaca aattgactat ttgctagttt tttatagttt gttatatcag
    27901 ttcgttttaa ctcggttgtt taaaaatgct aaggaagaat tgatcctgaa ttctgattat
    27961 gaaatagcaa aacaaattgc aagtattaga aaagaaaaca aatctgaagt aatcaaatta
    28021 agaaaagaat taagtattgc gagtaaagaa aacggtcggt tagaatcttt agtcaaatcg
    28081 gcaaaaaaag aagaggaact tttgaagcaa gagat
//
LOCUS       DAFELK010000034        27994 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFELK010000034
VERSION     DAFELK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.035"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(977..1150)
                     /locus_tag="LP433_001764"
     CDS             complement(977..1150)
                     /locus_tag="LP433_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005929.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(1153..1551)
                     /locus_tag="LP433_001765"
     CDS             complement(1153..1551)
                     /locus_tag="LP433_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005930.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1767..2822
                     /locus_tag="LP433_001766"
     CDS             1767..2822
                     /locus_tag="LP433_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HBL2005931.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2842..3195
                     /locus_tag="LP433_001767"
     CDS             2842..3195
                     /locus_tag="LP433_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005932.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3377..3673)
                     /locus_tag="LP433_001768"
     CDS             complement(3377..3673)
                     /locus_tag="LP433_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005933.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3677..4495)
                     /locus_tag="LP433_001769"
     CDS             complement(3677..4495)
                     /locus_tag="LP433_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2005934.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAVNENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWMVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4721..4942
                     /locus_tag="LP433_001770"
     CDS             4721..4942
                     /locus_tag="LP433_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HBL2005935.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            4944..5210
                     /locus_tag="LP433_001771"
     CDS             4944..5210
                     /locus_tag="LP433_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2005936.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5323..5862
                     /locus_tag="LP433_001772"
     CDS             5323..5862
                     /locus_tag="LP433_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005937.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGAYSSANEVIEEKKGYAKNGLE
                     IVDTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKQQLDRIKEENNKPNLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVA"
     gene            6070..6252
                     /locus_tag="LP433_001773"
     CDS             6070..6252
                     /locus_tag="LP433_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBL2005938.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAETYTSKATGLAVSS
                     FLTLLTFFVTLSFSFV"
     gene            6356..6640
                     /locus_tag="LP433_001774"
     CDS             6356..6640
                     /locus_tag="LP433_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005939.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            6914..7168
                     /locus_tag="LP433_001775"
     CDS             6914..7168
                     /locus_tag="LP433_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005940.1"
                     /translation="MNYTDEEQITLEYVFTNEKGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            7250..7435
                     /locus_tag="LP433_001776"
     CDS             7250..7435
                     /locus_tag="LP433_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBL2005941.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            7502..7897
                     /locus_tag="LP433_001777"
     CDS             7502..7897
                     /locus_tag="LP433_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBL2005942.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELFEK"
     gene            7887..8264
                     /locus_tag="LP433_001778"
     CDS             7887..8264
                     /locus_tag="LP433_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005943.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            8286..8661
                     /locus_tag="LP433_001779"
                     /pseudo
     CDS             8286..8661
                     /locus_tag="LP433_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8967..9365)
                     /locus_tag="LP433_001780"
     CDS             complement(8967..9365)
                     /locus_tag="LP433_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBL2005944.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(9556..10323)
                     /locus_tag="LP433_001781"
     CDS             complement(9556..10323)
                     /locus_tag="LP433_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2005945.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPNKLKKT
                     GEIVLPVKAIIKYMDVDQNLETELKNIVNTLQRQAVYEISNLDKEYKTYATVSAIDQI
                     HWDLEEQIITFNFSQEVIPLILSIKKKYPYFVFQDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            complement(10358..11581)
                     /locus_tag="LP433_001782"
     CDS             complement(10358..11581)
                     /locus_tag="LP433_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HBL2005946.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            12562..13365
                     /locus_tag="LP433_001783"
     CDS             12562..13365
                     /locus_tag="LP433_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2005947.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            13950..14405
                     /locus_tag="LP433_001784"
     CDS             13950..14405
                     /locus_tag="LP433_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005948.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            14524..15582
                     /locus_tag="LP433_001785"
     CDS             14524..15582
                     /locus_tag="LP433_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HBL2005949.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            15624..17573
                     /locus_tag="LP433_001786"
     CDS             15624..17573
                     /locus_tag="LP433_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBL2005950.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            17576..21217
                     /locus_tag="LP433_001787"
     CDS             17576..21217
                     /locus_tag="LP433_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005951.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            21617..21955
                     /locus_tag="LP433_001788"
     CDS             21617..21955
                     /locus_tag="LP433_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005952.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            22065..22286
                     /locus_tag="LP433_001789"
     CDS             22065..22286
                     /locus_tag="LP433_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005953.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            22306..24462
                     /locus_tag="LP433_001790"
     CDS             22306..24462
                     /locus_tag="LP433_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005954.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            24474..24707
                     /locus_tag="LP433_001791"
     CDS             24474..24707
                     /locus_tag="LP433_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2005955.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            24697..25563
                     /locus_tag="LP433_001792"
     CDS             24697..25563
                     /locus_tag="LP433_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005956.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            25578..27548
                     /locus_tag="LP433_001793"
     CDS             25578..27548
                     /locus_tag="LP433_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005957.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            27715..27942
                     /locus_tag="LP433_001794"
     CDS             27715..27942
                     /locus_tag="LP433_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005958.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFNEVKGMREQYEVVEA"
BASE COUNT        10031 a         4253 c         5044 g         8666 t
ORIGIN      
        1 acttttgttt cgtgttaagt ttctttacat tcctacgcac ctcgagtgta aaatttcttt
       61 attcctccca cgctccatgt tattttatat ttcctttttc atgttatttt tatccagaaa
      121 ccgatcaagt ttttacctat tcccaaaatc catttattcg ttattttttt cactgattaa
      181 gaataattat ttgatgctta aattagctaa aaaagcgatt tgttactgat ataatcatga
      241 tattgcagct gaattaggcg gaaagataaa atgttcgcaa aatcaaagta tcaattatct
      301 tgttttttta taaatttgta agtaaaaatc taaaaaagtt ttcttttaat tggtatatgt
      361 attaaaatca catttaatca cccataaagt atgcgctttc atttttttgg atgagattaa
      421 tatcaataaa taacgatgta aaaatcattt attatgctct tttataagga tattaattga
      481 tctaatttga aaaaaaatca aaatttaaat gttttaatat tacaaataaa atcatgttat
      541 tgtaaaatgg tataaaaaag ctaaaaattc tatttttgtt attttattag caggaaaatt
      601 taaatagttt tacaagaatc cgtagaaata tattggtttt gccttcagat taatactgga
      661 tcatattaat ctgaatataa tatatgaact aataaatagc ttaacctcgc tattttgttt
      721 tttctgatca ctatctatac agcattagta aatagaattt taaaaataaa aaaattaaga
      781 caaaaaagta tcaacataaa catatacata tacacgttta tgttgattca cttaatttgt
      841 cctttaaaaa gcacttattt taatataatg ttattttata atcttattac aagctgattg
      901 ttaggcgttg tcctttcatt acatttatta acggttattt tattgtttaa tttattaatt
      961 atttttgatc taaaacttag cttaacaaat aaataattaa ccaaccgcca gataaaaatg
     1021 cgatcattgc taatacataa gcaaagataa aaatatgttc gatcagctta aaccctgatg
     1081 cgattaagca gaccaagtaa aatagaaatt ctcttacaga taatggtaat tttctaacta
     1141 gcatactcat aattaacacc ccaaagtaat attgtatttt gaacatttta catccaatac
     1201 agcatcaatc aaccattgcc aatcaaaaat acaaggcttc attgaagtat gtttttcaga
     1261 tgaaaagata taatataatt tcttcggaat aatattttca gttgttggga tcaagctaaa
     1321 tctaataccg tctaactcat agctaccagc tttctctcca ttaaaaattt ccttagcact
     1381 ttcttctaaa gaatcaaaat atttttcgac agcaatcttt gaagctttta ctattgaagc
     1441 atttcccttt tcgataaaat ctgcttttgt tttaccgaca ataagtaatt cttgatcagt
     1501 aaaatcttct aaaataatgg tagtgtaatt cttatttctt ctcaatcgca tcaggatcac
     1561 tccttaatat aatttatgtt tttataatat cataataaga taaatttgca agcatttatt
     1621 tacacctttt tatttacact ttattataat taattagact tttatgattg catttttttc
     1681 ttataaacag ttgcaactaa tagtaaatag gtgtaaacta ttttcgtacc gaaataccat
     1741 aaacacaaac agaaagaggt cataccatga aagaaccatt attgttttcc gttgacttag
     1801 ggaataaatc agtaaaagaa atgagtacac acgtttctcc actctcactt ccctctcgta
     1861 ttttgaacaa aaatatcatt aattcaggac gtttttctaa tataggttcc tcattaaaac
     1921 gatcactaaa cgtttctgaa tatagcctag taaacactac tgaaagctat tactttggga
     1981 aggatataca cgagctagga aaagatgact acgtgataga atcactaggt tttgggatca
     2041 gcagatacaa gcaggaaacc taccaaaata tcctatcttt ctctttagct aacctagcac
     2101 gtttagaaga tcaatctgat gacgttttaa ccgctaatct agttttaggt ctgccttcat
     2161 ccgactatac cgaaacaatc gtcaaatacg tgatgcaaca agccacacga caacattcag
     2221 ttgaagttga cggtaaagct tataatataa acgtagatac cgtttgggta ctgccacagc
     2281 cgattggaac actatataac ctcctacttg ctgatgatgg tagtgtacaa gatgaaacat
     2341 tgatcagtca gaagatcggt tttgttgata ttggcggtgg cacgaaactt tttgatgttg
     2401 tccaaaattt tgaaattgac gaaaacaatc gtgaacaaaa ggataccggc atttttactt
     2461 tatataatcg tatcgtaaat atgcttgacc ttccgatcag tcctaatgct ttccaacttg
     2521 aaaagattat ccgagaaggc aaagaaaaag gcgtatatct atttaagcca agcggaaatg
     2581 aaagttttga tatttcagaa gtagttgaaa gagaaataaa aacatacacc aatatggttg
     2641 ttgcagaagt tttagctaca ttcaaaaact tcacaacctt agataaagtt gtctttactg
     2701 gtggtggagc ttctattatc gacaaacaac ttgtaaaaga taaaattccg cataccttgt
     2761 ttgttgaaga cagtgaattt tctaatgtaa aaggctttta caagtttggt ttaactcaat
     2821 aaaacagcga aggagatcaa catgaataag ggaaaatcag agcgttatgt agttataatc
     2881 aatagagaaa aggttagcga gttaccttta gcagagtttc ttgaatccga atatgaaaca
     2941 ctaggcgtta aatactctca gacgatcaaa aaagctttga acctatatcg gcgtgtaaag
     3001 aacaatgaag ttacaattat tgaagcaggc aacgatagaa acgatagcaa agtagcagaa
     3061 gtaaagaata aaccaactga tcataaccct attcaacaag agcatccttc aacggttaca
     3121 tccgatcatt cagcaaagaa agaaaagcca atgctgaaag ggttcaatgc accaagtaac
     3181 aaagacttac tttaaaaata aaaaggcgag gttacaatac ctagcctttt tattatgtac
     3241 aaatataaac ataaacatat acgtatacat gtatataaac atgtatacgt atatatccat
     3301 aaacacgtat attaaattta gttaagctat acctaaccgc ttattccaat aaaaaaagtg
     3361 atcagcttta aactgatcac tcaccaaaaa cttcatcata caagttatct atcatttcac
     3421 caagtaaagc tgaatctgat cgaattccta acttttcgct gattttagat agtttctttc
     3481 tttgcgatgg ttgaagcgtg aattgataat ttttcttctt ttcagaacta tcacttttta
     3541 gtttagctac caaagaactt gttgtttctt taggtgtttg tttaggttct tcaactgctt
     3601 caaccacttc aggaacttct tctacttcag cttcagcgaa ttttttaaat ctattttctt
     3661 tcacttcaat cactccttat tcttgtgccg tatcaattat tttgttgtat agcgtaaacg
     3721 tgctttcaaa gaaatcctta ttcttacgat agatattctt atccttagcg aactcagcaa
     3781 tattcttacc ttctaagcta gttgcattaa gcaattcctt ctcttgtaca tatccaagat
     3841 aattagataa cgttggtacc agttctagga actcacgact tgaattagta ttatgtttga
     3901 tcctgctacc gatcgtagcg tatttagttt ccatcagtgt ttcaccagtc ttaatatcaa
     3961 tcaactgttt tgctagtgca tcaatatctt taccaagctt cagcaaagct tcaaaaccat
     4021 ctttagatgg atcagaaatg cctacgacaa gatcagatac agcccaagca ttttgagcta
     4081 gtagacctgc atcattatga gtatcaatca gaattagatc atacttctct ttaagctgtt
     4141 catagttaac aaccatccat ctaaacagta gggttctgtt gttaggcata tcacgcattt
     4201 gcatctcaac ttgttttaaa tcttcacctg ctactaaaat atccatgttc tcatttacag
     4261 ctaaaggttc agctgatcca tgaagatata aatgattgat tgtattctct cttttcgctt
     4321 tactgaaagc atcaggaaat cgttttgata ggttttgcga cttatcttca tcaatataca
     4381 gcaccttcat acctaaattt tcgacagcat atccacctag attgtagatt gttgttgttt
     4441 tacctgttcc acctttttca atgtttccag taatgattga caacttcttt tccatgatta
     4501 aacctccctt attaaccttt tgtaactcca ttatacacta taaacacgtt tatgtatatg
     4561 tttatataca taaacgtgtt tatatttata tttgctttta tattctacaa cataaacata
     4621 tatatgtata tgtttatgtt tatgtatata ttcatatata taactattgc atttgtcata
     4681 caatcgtagt acaatgtaat tgaaaaggag ttgataaact atgccagtaa taagtattcg
     4741 tgtatctaaa gaagaaaaag attttcttga aaaagttgct gaattcaacg gagataacat
     4801 ttctgaattt atgcgtagta attccctgca aacagcagaa acgttagtag actttgccac
     4861 ctacaaggaa ctaatgaaag agcatgagga aaacgatcaa agtatttccc acgaagatat
     4921 gctaaaagag ttaggcttat aagatgactt accaagtaag atatgaacgt gaagctcaaa
     4981 aagcgctaaa aaaaatggat aagtttcagg caaaggttat cctaaactgg atcgagaaaa
     5041 atcttgtagg cactgatgat ccaagaaaac atggtaaagg tctaacagct aataaatcag
     5101 gctactggcg atatagggta ggtgcctacc gtataatagc tgatattagc gagcatgaag
     5161 tgacaattct tatattgtct attggtcaca gaagtgaagt ttataagtaa cagacaagct
     5221 gataaggctt gtctgttttt ttgttaaccc aacaaaatca ctgtttacga tcccacttta
     5281 cctaaaaaag aacaataccc tcttgttatt atacacactg gtgtgtataa tataagtgta
     5341 aacaagctaa ttaactttca aaaggagcga ttttttatgg gatggtatgg tgcttattca
     5401 tcagcaaatg aagtgatcga agaaaagaaa gggtacgcca aaaatggttt ggaaatcgta
     5461 gataccaaag taacgaagac ctatggtatt atccttttca aagatgcaga aggaacctac
     5521 gatattgaca gcttcatctt tcgagatgaa atgtacaaac caatctactt cttaaatgac
     5581 agtcctgctt actttaagaa aattccgaaa aaatggttga aattctttgt cggtgatcaa
     5641 gaaaaaatgg ttaagcaaca actagataga attaaagaag aaaacaataa accaaacctt
     5701 gatgacttat tagttgcagg taaaacttac tcaatctggg atggatcgta tgtcgctgtt
     5761 tatcagtata aactcaaacg tagctttatt tttagactac aagatggatc actcactcgg
     5821 ttcactcgac tatcagcagg agatgttaag gaagtagcct aaaacttaaa tacataaaca
     5881 taaacgtgta tacgtttatg tttatgttta tgtatatgta tatgaatata aacgtattag
     5941 gtacgaacgt ttttaaatgc ttttctgggc tttgatttta gggtagggct aaaacatcca
     6001 ttgatccaaa acagctcaga aacgcattta aacgtatctg ataccaatat tacagaagga
     6061 gtgtatcgta tgattaacct atttctttta gtgacagcta gtacattatt ctttactgga
     6121 atatcactga taatttccta tttgatctat aagaaagccg aaacttacac aagcaaagca
     6181 accggactag ccgtttcctc ctttttaact ttgctgactt tttttgttac tctatcgttt
     6241 tcttttgttt agcacagctg atccatcagc aaaaaacctc tctttacatt atacacacta
     6301 gtgtgtataa tgtaattgta aacaagctaa ttaactttta ggaaggagtg acaatatgct
     6361 aacagctaca ttacagcaac ctactcacgt tgctattgca gaaagctata caattaatgc
     6421 aggggtcgtt aaacagctga tcaaggatcg agaattcaaa aagtttaaca gtcgtcaagc
     6481 gtataacaga cagttaaaga aagctattct aaagcacaaa aattccttca tagggaaatt
     6541 ggaaagtgtg gatgttaaaa ctgtttcaac ggcattttca gttgttgaag tgactattga
     6601 cggtcgcttg atttctctat ttgcttttgg aattaattga tagggagtgt ggactttgga
     6661 aggtaagact tttgcagaaa tttggactga atttattgag gtaccaactc gcattgatcc
     6721 gataacttct gaaaaggtat tggatgcaga cttctacaat ctcaaagcag gtactagcct
     6781 tgaatgcgtt tagatgtatt tagaagagca tttcaaaggc gtaacgctcg gtcacgtctt
     6841 ataccacaat ggtgccgagt gggatgcaat tggaaatatc catttttctt aatacaagaa
     6901 aggagaacac aatatgaatt ataccgatga agaacaaatc actttggaat acgttttcac
     6961 aaatgaaaaa ggggaggaaa ttgaaaaagt cttgatcatt tcatcaaaag acttggagaa
     7021 cgctttgact tatgaaccat acgaatcaac cgtaactgtc aatgaattct tagataccta
     7081 tacttctaat gatacttggg aaattatgaa tatttgcaac gctaataaca ttcaatttgc
     7141 tgaaaaaacc aataaatcat tttattagtt ttgcaataaa acatcctctt tttctattga
     7201 ttccatacac aacaatgtgt ataatagatt ttgtaaaggg agggtagcta tgcctaagac
     7261 agcaagagaa attgtaaaaa ttctcaaatc taacggcttc aaaaagactg gacaaactgg
     7321 cagtcatgca aaattttata attccaagac taaaagaacg gtcgttgttc cgatccacaa
     7381 tggtgatgta ccactaggaa cagaagctaa tatctggaag caagcagggc tttaacagcc
     7441 ttgccttcct atttggtatt aggcatacta tcctctctta cactagaaaa ggagcgagga
     7501 aatgaagaca aaaaatattt tttatccggc aatcttcgag aaagaaggag aagcttataa
     7561 catcgttttc cctgacttac cggaaatatc tacctttgga aatagtcttg aagaagcata
     7621 tttaaacgct aaggatgctt taggattagc gctatatagt gtaccagatg cagaatttcc
     7681 taaaccatca gcagtggaag aattaacttt gaaagccaat caagtggtag taatcatcca
     7741 actaaacatt aaacttttcc gaagaagctt aaatacaaaa acaattagaa aaaatgttag
     7801 tgttccggaa tggttagttc ttttagggaa ggagaaaaac ataaacttct ctcaactact
     7861 tcaaaaagca ctagaagaag agttgtttga aaagtaaaaa ggagaccgaa cctatgaaag
     7921 ctacacactt aaactatttc tctcgaacgt taatcaataa tctattaaaa gatacaactg
     7981 gcattagcgt tagtaccaaa cactttgcca atgatctaat tatttttgag gataataact
     8041 tgcgaattga gatgtttatt gaacaggcaa cccctaactc aatacctgaa ttctgctata
     8101 cgcacactga aaaaatgaaa catgcaaaat cagttaaaga tgttgaagca ttaagtgaat
     8161 cactaacgaa cgctttaaac ctcgttaaga aggcaaaatt gttatttgaa tttcaaaccg
     8221 actaccacaa tgagttgctt gctcaatctg aaattttaga ttaattgaaa caggagaaga
     8281 gaaagatgaa acaaacacaa acagaaccca ttaacgatac gcttgctgat caattagcag
     8341 gatattataa attatttgag atgagtaaag cacagcgctt gatccactat ctttggaaat
     8401 acaaaatttt gtttcttttt tgggaagcaa cactaacatt ctcagttctt tttttataag
     8461 tcagattgtt ataatcaaca cttagtttta gggagttttt tgcttatcta caccattttg
     8521 atgcttaatt tatataccta catcacactt gaagaacact tagtaattag cgatgcaggg
     8581 atcgagagaa acatcaaaag ggtatctttc aagatcacgt taaacaagcc taccgataaa
     8641 aagctctcag aagcgttctg agagcttttg acattttctt gtataattta tccaaacaca
     8701 ttacaaagca cctaattcga gcttatatca agcaaatttg ctatttattc ctcaatacat
     8761 atctaaaaat tacttgatgg aaaactagat acatggtaag catgaaaaga aaatcaattt
     8821 gagcagatgc agtataatac atagcaattt aaaagctctc agaacgcttc tgagagcttt
     8881 taatatattc tttgataatt tgtctttctt aaatccatac gtcctaaaac aagctgtttt
     8941 tgcttaatat gatcatctga gagacatcaa atcaactttt ctctcaacaa atcattcaaa
     9001 gctttcgaca gattaatatt ctcttcagcc gctaaaacat ttaaatagtg ttccacagtc
     9061 actgattttc gatcgtaatt ttgcttgttt cgagctttag caactttcgt attagctttt
     9121 acgacaaata aattaacatt ctcagatcgc ttgattcttg catttaactc ttgaacaggc
     9181 gtaggcgatg gaatttcttt ttcttgcaac tctaaaagca ccaagtatcc ttccaatact
     9241 tcttgcgcca tctcaaaagc atcttctaaa gtttcaccat gcgtatataa gtctggaaaa
     9301 tctgggaatt taactgcata ttcatttcct ttccattcga atactgcaca aaaaaagtat
     9361 ttcatcgcat tgcacctctc taattaaaaa ataatttttg ctttttagtt tcaaaaaaag
     9421 aatcgcctac caaaaaaatt gataggcgat cacaagctaa ttaacctcta aaggagatta
     9481 ataccttgct cccaaggcac tacatatctt agcatacgtc tgaagcatct tcaaacgagt
     9541 aagatatatt ttgcattaac ctaatttttt ttctctataa ggtttttcat caaactcact
     9601 agaaatatta aactggacag caaaattgta atttctgcct tttctaactt tagcaaaatc
     9661 aatcttcagc attgattttt cattaatttc ctcaactgat tcccttaaaa cacgtctatc
     9721 aaaattcgat attgttttgt actcattttc tgttttcgta atctcacgaa ttttaactat
     9781 ttcaatcagg ggattcttat atatttcagc tttctcaaaa tctcctttat ttttggcgat
     9841 aagatatttt ttataataca tcgccaaata tttgtataac acaatgctat attttttttg
     9901 aaagcttgct aaatcttgaa aaacaaaata tggatatttc tttttgattg aaagaattag
     9961 gggaattact tcttgcgaga aattgaaagt tataatttgt tcttctaagt cccaatgaat
    10021 ttgatcaata gcagatactg tagcataagt cttatattct ttatctaagt tcgatatttc
    10081 ataaactgct tgtctctgaa gggtgttaac tatatttttt agttctgttt caagattttg
    10141 atcaacatcc atgtatttga ttattgcttt aacaggtaaa actatttccc ctgttttctt
    10201 taatttgtta ggagagatat aactgaacag caattgataa agttcatacg actttaaatc
    10261 cattttcatg tcaattgttg ctaagaactc ctcattgtac tttgtcagtt catctttttt
    10321 caaaagtttt tccttccttc acgcattttt tcagttgtta atcataaagg ttcacataag
    10381 gcaaataact cgtaattgat ttttcgagat atttaacagt attttttatt gtgtaatcct
    10441 ccttatgagt agcaacgtaa gataggtgat tgacaactga ttcaaatcct ctatctttgg
    10501 ataaacgatc ataaagcgga taaactttat tctgaagtcg gctcataagt ttaagatcgc
    10561 ataagtcggc agaactgatc aaaaagtttt tgattagtaa tttagtgtat ttgctattca
    10621 tagctttcaa gtacgattga ttcattttct ctgttttatc ttctgcgcct tttaaataag
    10681 cagggtctct ttgttcttgc ttataaggta ccggaactga catggtacgt gtaagcaaga
    10741 actttatgtt tgtataagta tgacccttct tgataagctc atagtcaatt ttaaaatcag
    10801 tgtatttatt cagttgggca atcggttctt taattacacg tctttcaaag tctcgaaaag
    10861 ctttatattt tttctcaata ctaaatttct ttcgtaaatc tgcaatggag aaaacaggat
    10921 tttttaatct atcaagtgat tttgtactcc atgttaagtt atctctattt gcttcataca
    10981 gattaaaatc tttagtgaat aattgaaaaa aactgatcgc atacttgctt gtcaagttaa
    11041 ctacttgatc aaatgtatat tgcgtaaaat gatcttctaa gttcgttaat aaaggcataa
    11101 ttgaactact aaatttaata gatactgcat cagaaaaatc attgaattca gtaatttcta
    11161 gcggtgagat gactttgtat tcagtcttac cgttaggttt agttctttga attttaatga
    11221 cagattgctg atgcaatttt tcaataactt gttttaatct tgaatgtttt gaagaagatg
    11281 aactagaaga catcaacgca aataaagcct ttttagatac tttgacggta ttattaaaag
    11341 gcggattttt agggtcaaga tgtcctatag cgtaaagata aattttttgt ggcatagcat
    11401 ccatttcaac aatgctatct acaagttgat tcgataaagt aacagttaaa tcaaactttt
    11461 ttagattgct ttcggtagtt tcaaatttcg ggtttacatt cttttctgtt attttcatac
    11521 gattgcctct tctttctaag cttggtacga gcttaaaaac ttggaactgg tacgattcca
    11581 ttgaataagt atagacctgt tttcgatacg ttacaataag aaatgtatcg taaatttata
    11641 acataactca atgtcagtaa aacacatttt attttttcca atcaaatttc attgaaaata
    11701 cagcagaaat cgctatttta gaacattttc aaaataaaaa tccttttcaa taaaatacga
    11761 aattataaaa attaccaaaa ttaaaaaaca aatatttttc tagtttttag aaataaattc
    11821 acatactttt tctttttttg gatatattcg gaataccaca tcgctttttg tccacgtttg
    11881 catcgctttt tgtccacatt cacatcgctt tttgtccatg ttcgcatcgc tttatgtcca
    11941 ccctaaaatc tatttaagat tgatataaag cctttttgga ggttgctaaa gttttaaaga
    12001 ttaaaatata tattataaat ataaataaaa ggggaagctg aagcttcctc cttttccttt
    12061 ttttcaatta ttcaaagtta cacaagcaaa ataaactcct agatagtgtt agtttttttt
    12121 aagatttttt atttttaaga ttttgaaata agagaggagt aatcctcctt tattaaatat
    12181 ctgttaatat atctgttaaa tatctgttaa tatatctgtt aggggaggct taatctcttg
    12241 ggagagtaag tattaaaggg gtataaaggt aacacttttg gacagtaaag gtaacaaaag
    12301 tggacagtaa gggtaacagt tttggacagc aaaggtaaca aaagtggaca tttgaggtat
    12361 cacactagga taagacgtta ccttcggttt tcttgatttg gaaggcgaaa aaatagaaaa
    12421 ttagattagt aacaaatctt tgttgactgt tacctttagt tgtgatttaa tttaggtaac
    12481 aagcagaaaa aattgtttcc tttaattagt accagattaa catgattaaa ggagcgcaaa
    12541 aagaagattg gagagtaatc aatgtctcaa gaagttaccg aaaagattat tgatagtgat
    12601 gtagatttag tatcagaaca aacaaatgca attgtgcgtt ataacaatgg tctgaataca
    12661 acagctttgc gaggatttaa gcctgttgaa atggatgtgt tttgggctat tttatcaaaa
    12721 atgaaacgtc aaggaacagc agaagtaact tttgatttca acctctttcg ttatttggtc
    12781 aaatacgaca gaagagaaaa ggacagtttt tattctgtgt taaaagattt gagtgacaaa
    12841 ctaggtaatt taacctaccg ttttgaagat tcagacgtct atgaacagct gtggcttttt
    12901 caaaaattcc ggatagataa acagaaggaa acagttacaa ttaaggcaaa tgaggaattt
    12961 gaatttatct taaactcaat tggcaaaaac tttactcgtt ttgaacttga taattttaca
    13021 aaactaagaa gtagctacac aaaagaattg tatcgtcatc tcatgcaata cagaaataaa
    13081 gagtggcgaa atggttattg ggtagtcaaa gttgaagatt ttagaagagc attaagtata
    13141 ccttcaagtt atagaatgac aaatattgat aaaagaatac tagagcaggc gaaagaagaa
    13201 tttttagctc ctgatgaaaa cggaatacag gtatttgaaa cttttgatta tgaaaaaatc
    13261 tatgcaaaga aaggaagaag agttgatcgg ctcagattca cttttagtga gccagaatca
    13321 aacttgccaa ccatttcaat gcataattgg ttagaagaag attgagaaga agcaggttgt
    13381 aattttaata caacctgctt ctttaaaaaa gtatgggtaa cacttttgga caataaatgc
    13441 aagaagtttt tttgtaagca agtttcagtc taaataatat ttgaaagaat ggctaatcta
    13501 tacaaatttt aacaactatg ggtaacactt ttggacaagt caagaaaaaa aacaattttt
    13561 cttaatttgt tgatcgacta aaggtaacac ttttggacaa cacagaataa aaagtccggt
    13621 gatatcagtt ttggtaggaa acatcttaat atctttgtga gattgaaggt aacatttttg
    13681 gacaagtcaa ctatttgtta aaagttaata tagagtaatt agataagttt tttcttttcg
    13741 tctgataaat ggataatatt agttatttta ttgctaatta gtctttcatg atgactgaaa
    13801 tagctaaaat aaatatctcg ttggataatt gctgatactt taagggatat ctaaatttgc
    13861 tgattgattt atttatgtta ttatgatatt ataataacat aaatgtgtta cgcccgaacc
    13921 tcattttaaa aaaatgaagg ggtgagacaa tgaatgctat taattggcat gaatttgtta
    13981 actatatgga gagcttacta gatgatctaa aaagttttag tattgctgat gcagtaaagc
    14041 atgggttacc agttagtaca acgatgaaat tacgaggatt gaaaattcca gatgaaatta
    14101 ttaagctgag aactaaaaca attattgaaa ccgcaaaagt cgttgacaat atgaaccatg
    14161 aactaaaagg caagaaaaca acttacgaga aagattttga acgtttttta aaatctgtta
    14221 ttggaaaata tctaggtaaa aaatctttca gtgaattgag agatgaagag attgtaccta
    14281 ctccaatggt tagcaaaatc cgaaaaaaca aagccgaggg gaattactat cttggtacaa
    14341 tagcaaaaat cattgattat ttggaaaata aagagcaaaa gaaaggaacg aagaaaggaa
    14401 gataattttt gtgttaaata ttaatgggga agaatatacc gaaatgattc aaaatcccga
    14461 acctagaatt accgaaaaaa cgtctgattg tttgctcttt tatgaaaggg ggcagacaaa
    14521 ctaatggaaa aaaacgtcaa ttcaacatct accaaagatc aatacagtat tattggaggg
    14581 ttgcttggtg ataaggataa gagaacacgt cacggattac gcattatgct tgcaactttt
    14641 ctaggagtgc tttttttatt aacaggcttg ggtagctaca tttatcaatt aggaaactat
    14701 aattattatc tcgtgaacaa tacaacacct ataggctctt cattggagtt tgctcgatca
    14761 ggagcagaga tcactatttc agatgtgtgg acagatcaaa acagagatgt aacagtagta
    14821 aaactcggtt actcgcaaaa cgctagaaag ttgttatcta cgcaaggaaa aaactacaac
    14881 ttatatatgg caacgaaaga aaaagatcgt cctaaaaagc ttgaaatgag ctatgggatg
    14941 ttaagtactg atggggatgc tttcttattc ctaaaaggta aattagatga aagagcttat
    15001 caagttttta ttgcaaacca agtatcacta atttctggtg atgatacagc tgacgatgat
    15061 accaaagtca atgtgaatga agcagattca gttacaaaag cactttctca atattctatg
    15121 aatgatgtta ataatgaagg agtaatttct tttgggaaaa aagcaaaacc tgttaatact
    15181 cctgataata tcaatttcag aataaatcca tattcagatt caactaatgt ctatcaagga
    15241 agctttctta ccaaagatgg cgatattgat tattcaaaag ttgtagcagt tacaagtaag
    15301 aataatgttg taagtaagtt agaagatcag ttaaatgctt caaatactaa catcaagaaa
    15361 attgaagcta caaaagctga gtatctggaa cgtttacaac aaaatcctga cgataaagat
    15421 tcgcaagaaa gtattcgtca actagacagt cgaatggaga ccgaaattaa agcaatcaat
    15481 gatacacaaa aattgattga tcaatacaaa aatgctgact ttaacaaaga ttcttttgga
    15541 gacatgaaga cgacatttaa gtacctaact ctgactgact agaagtaaat tattcttatt
    15601 ttagaggaag tgaacacaaa cagatggaaa atagtaccga gttttttaag aatattcaaa
    15661 ctgaatttaa tcatgctctc acaccaatga aaccaccgaa acataagtta gtgggacgtg
    15721 atgacgaact ccatgagttg tcactgatct tgaatagacc ggaaacaccg caagctatct
    15781 tgttaggtga agccggaaca ggtaaaacag cacttgcaag tgaatgggct gaaagacagc
    15841 gacaagatgg aaagaaagta caagtataca aattatcaat cggacaattg cgtgttgggg
    15901 gagatgatgt cctccaaaca cgtttagaaa cattaattcc aagattgaaa gaatatgagc
    15961 gaattttaaa atctgaggac aaagaaaatg aatttgtcct cttcattgac gagtttcata
    16021 aagttgttag ctcttttggt agtggcaata aaattggggg tgattcgcta aaagaaccgt
    16081 tagcaaatga atcacttcaa ttgattaccg ctactacaag aaaagaatat gaaaactata
    16141 tcaaaagaga tgatgcctta gggagacggt tacaaccgtt agaattgaat gaactaaaaa
    16201 gcgatgttgt cgtcgatatt ttgagacaat ggctaaatac atcctctgtt aaagatgatc
    16261 ctcaggcttc ttttaaatta tcgcaaagga ttcctgatga attacttcaa gaaatcgtac
    16321 aagcaaacaa gctttatcgt gaggatttgt ccgaaccggc taaatcaatt gccgtaatgg
    16381 aggatttgat tgcaaaagat cgagtagacg gaaatgctta taatcgagaa agtctattgc
    16441 aaatatttgg taagtataat attcagctag attctgattt tgatatggaa aaacttcaag
    16501 aggaattaaa gtccataaaa gggcaaccgt tagcagttta tactataaca atgttgttta
    16561 aacgtatgaa gcttggattt gatcgtttta aaggtcgaaa gcaaccaaaa gcaactgctc
    16621 tgtttacagg atcaacaggg gtcggtaaaa ctgcaatggc taaagccgtg gcaagaggac
    16681 tttatggcga tgaaaataaa gttctcttag ttaatatgcc ggactacaaa acaaaagatg
    16741 atgcaatgcg ttttagacga ctcataggta ctcatgtaag gcatgatcct tctgcgatta
    16801 ttgtgtgtga tgaatatgag aaagctggtg tagaaacact cgatgccttt ttatcaattt
    16861 tagatgaagg taggataagt tttactgaaa gaggatggga tgatcgagaa gttcacgaca
    16921 ctgtttcatt gtcaaataca attttatttg cgacaacaaa tgcaggtgcg gagatgttcg
    16981 attcgttaaa cagatatagc tcactatctc gtgttacaaa caaggaaaat tctaatgaat
    17041 atagcactga actaaaaaga gaataccgaa aagtcgcatc agggatcaaa caagccttga
    17101 ttggtgaagg tctaaagcct gaagttatta accgatttgg acgaatagtt ccattttggg
    17161 ctttatccga acaaactctt ctggaaattg cttataatga aatgttgaag agtgctgaat
    17221 tagtacgaaa acatttaaat atagatttac gtcttccacc taggaaagaa agagtatatg
    17281 gtcaaaattt ttatgcagac gatctctcca tgcacttagt ttttgacatg gcttcacaag
    17341 aggattctaa atcagggggt gcaaggaata tcttgcattt agttgaatct gagtttgaag
    17401 aagcgattac tgaagcaata attacttatc caaacgcaaa aatattcgat gttaagttga
    17461 gtgaagccgg agcgtttgaa ggaaaaggtg attctaatgc tgaaattatt gcaaagcctt
    17521 ccgttgctga aagtaaagaa aacaagattg tattttcgat tggaggggcg tagctatgaa
    17581 attcaagaaa tatttactac aaaaccttag aataaaacga tgggtcgtaa gaggtctagt
    17641 tattggagga gtattagcag ttactttagg cgctcctttt ggaatgaatg atccaactcc
    17701 tgacaatcaa gatagcaaac aagaaacagt tataaataag aacgttgcat atgcggaaag
    17761 taaaccggca gaacaaggaa tgtggacact atatgctcgt atcctaatgg gagataaaga
    17821 agttaatgat agtgccgcta aaactggaca aatgaatttg ttaggacaag gtggtatcag
    17881 tgccgatttc ccttattctg acatttctaa acaaggtaat tcgattgcag ggggtaatgc
    17941 aggtactcaa ctagcatcta ctttagcaac ttatagttac tacggatata ttgaaacagt
    18001 ctcaggaaat gctattgcca gtcaagcatc atccattcta ggaagtattg gtaggacgat
    18061 tggtagtttt atcggatcaa ttagtttaat cctttctaat attgctgaat ccataaatga
    18121 actccttgga aaatttttca tgagtatgaa tatattttct cttatggggt ggggagaagg
    18181 tggatcggat gtatctaatc cggtatctaa agcattaact agcttgctta acaatttggg
    18241 attaaataat gaattattta aagcgatagc aagcttatct atgctctttt tcacagcaat
    18301 actaggttat caaggaatga aattattgtc gaaagatggt gttaactcga agggattatc
    18361 accagtactt gaaaaatgga ttgttcgtat ttttgtattg tttatattct taccagtggc
    18421 aggatcgcta ttgggagttt atatcaacgg catccagtca gcaaaaaaag atggagatat
    18481 accaacaaat gttgtttctg actacatcat taacacaaga ctttgggctt ctactcaaaa
    18541 tcttgctcca tcatctgata ctggtggtga tgtacctgac ggaaagccta catccgaaat
    18601 caagttcgtt gatacagatt atgaaccatc taaaaaatct gcaatgataa gagcgatcaa
    18661 tactagcagt tatgccagac aaaataatga tctagattct aattcagtcg gtatggctct
    18721 attaaaagaa tggtcatcga atgatacttt caatattaat acttatgccg gtgatgttaa
    18781 tgtcgccgaa aatgatgctt atatgggaag agcgcctgct gtttggacag gctataattt
    18841 aggggatgga aaagaaggaa gtgcaattaa gaaaccaacc aatttaaatg gatatatttg
    18901 gtcagcaaat caaaatgtga cagacgacaa tcgcaagcct gatggaaaag gaacagcgca
    18961 taactttgat gctactcaac cttggggcgt tgctaacaat gcaactttta gcacacagtc
    19021 ggtagcttta ttgctccaat cggcacttga tacatcggga gctaagtttt atgcgtataa
    19081 tatcgctcct tcaggaattc aaggcagtgc taagaatatg tcaacagtaa aaacagaatg
    19141 gcgtacagca tccttagttg gtcatggagc tatgggtaag tttggctcgt ggctagcgat
    19201 gaacgctgaa tcaatcgttt tagcagttct ttacttagca tgtgcttggg cgatgttcaa
    19261 tgtgaatatc gtgaaagcat ttaaacgtga atttattcgg atttgggaag tagttctaac
    19321 aggatcactt gcatcaggag caggtgtgat ggcaatttca ttaggtgttg ttacaacatc
    19381 tctgatcgga ctacaattac ctatctttct gattactttt attcgtgcat ttggtgatac
    19441 tgctgtggga ttcattccta atacattagt tggcgatggc gtagcaaata ttgttcgatc
    19501 tgctatgatt ttaggtgtag gatatctttt agtctttaaa aaaggcgaaa aagtaaataa
    19561 tttgattaat atgcttattg gcttaccact tgaagtagcg tttgggtttg atgaacgtgc
    19621 taagttatta tttggtaata gaaatgatgc tgtgcgagtt gtggacggcg tttctaaagc
    19681 aatcaagaaa agccaaggag ctaaaaatcc ctattatgat ggtggcaaca gctcagtaaa
    19741 agatatggtt gcaggaggtc ttggagcagt tggagcgcaa aaaatggctg aacgtttgaa
    19801 caatatggga gatagcaatg ctgatgctaa gtccattgct gataaagtaa ttcctgaaac
    19861 accagaagga atgtcattca acggtggcgg agttggttcc acaatcaata atacctcttt
    19921 caaagattta gttcgtcaag atcaactacg taataactcc caacaatata ttgatcattt
    19981 aggacgtatg gttgatgaaa acggaaactt tgtcgatgaa aatggtgaaa tattaaaaga
    20041 tagtaaatac ggtaaagatg ctaaaggcaa ctttattgac gaaaaagggc gtttggtcga
    20101 tgaagatgga aaccttatag atactaatgg taaaccattg gaagatagtg aagatggtaa
    20161 tattggtatg gatagcgaag gacgtttaat tgatgaaaaa ggtcgcttag tcgatgaaga
    20221 tggaaatctt gttgacgaaa atggacgcag gttgctaaat ggtgattttg gtcatgatag
    20281 taacggacgt ttagttgacg aaaaaggtcg tttagttgat gaagatggaa atcttgttga
    20341 tgagtttggt aataaacttg gtaaacacag cgatggatat aatgtgaatg gagatttagt
    20401 cgatgaggat gggaatatca ttgagacgag agatgcgctt gtggcagatc gaaatagaga
    20461 actcgaacaa caacggcata cgccaattgc tgttgcaatt cctgagaatg aagaagacga
    20521 gattacttta gatcaaactc atcaagaact gaggaatgaa atgagtggtg aggacgtgtc
    20581 agacagagtg catcgggaat taggagatgg agcatctggt gaaagtcagt caagagagct
    20641 taacagcaac tttgataata gtgctattcg gaatgacaca gtacttaaag acagagaatc
    20701 gctaacaaaa gaaacggata aagaacaatc agatgtgaag aaaaagttca ttcctactcc
    20761 taatgttaat caaacagata aatatgaaac aaatattgga tcaggaatgt cgaaagacaa
    20821 tcaatcaatt agagaacctg aactgacaaa taaaaataat agaacaaata attctaaatc
    20881 tacttcagat aattcaggga aatctaatca atcaaccaag aaaacatcaa cagctaaatc
    20941 agccgttgaa tatctatcaa aaactggtaa aaatgtttac acctcagcag ataaagcttt
    21001 agcaaaagct ccaaaaggta gtctagcagg gataacctat gaagctaaaa acgaagctat
    21061 taaaataggt aaaggaacgg ctaaggttgc caaggctact gctacaggag catccaaaac
    21121 tggtaaagta gtgaagaaat ctaccatgtc agtcaaggac tatattgtaa aatacggtaa
    21181 tcaaaaatca actgaaaata agtctgaaga cgagtaaaaa gaaggagcat tgatttgctc
    21241 cttcttttta ctttgatttc taactgaaga tgtcaaggaa aatttctatt tatgcaaaaa
    21301 aattatttta aattgtctat aaatgaatta aatatttact gttcaaagtt gtataattaa
    21361 aaagggctta tgctggtaaa gaacagaatt attatctaaa caaaaacttg ataaaccagc
    21421 atttttagcc aataaaaaaa gtgaaataat ttaatggaaa atctctttta atcatcgaaa
    21481 atttatgtta ttatgataac ataaagatgt aaatatcgag acgtcttttt cttagttaga
    21541 tcattgacaa gtgaacaaat aagatttgtc gatgatataa ttaacttatt aaaaatatta
    21601 aaaaggaggt ttttatatgt tcgattctat taaaaatttg gttagcggaa tgacgcctga
    21661 tatgaaaact ttagtacaag ttgttttgta tttcttggca ttcgtttttt cgttgaaacc
    21721 aggattcact gcaatgaaat tttttggtga tgcaaaatgg ggagatggat taaaatatgt
    21781 tggggcgatt attgcaatct ttattattcc tgtaattaca accgttatgc tttacacaat
    21841 gggtactaaa acaggtaatg atttgaacca aaaagctaat atcatatcag cacttattcc
    21901 agttgttggt atctatctag tttcaaaatt tccaaaaaat gaactgttag gttaaaagtg
    21961 aattgaacaa atttggataa tatgccgatt tgttcaattt actttttacc aaaaaactac
    22021 gctccaagcg tagtttagaa gtgagggaag aaagtaaatg taagatggtt tttgatagag
    22081 aaaaaatgtt agctcacgcc aacgaagtat taatgagcag tctgaaaggt accgaactgg
    22141 caaagataat gaatatgaat gttaaccagt tctatgatta tcgaaatggg agtaaaaaga
    22201 ttgaaaaagc cagacttgaa acgcttatta aattcgaaaa agcatatgta tatatgctag
    22261 ataaacagaa aagaactatt gactgaaaaa aggagtttta caataatggc aaaattcaaa
    22321 gatattaccg aatctattaa ttatgtggca gaaacagttc ctgtagttgc actctctttg
    22381 aagccacaat tactcgaagt gtacaaaaaa gaagaaaaag aagcgaaggc aaaaaaagct
    22441 aaagcaaagg tatggaaaga attcgatgcg ttgctgacca aagatttacc aaagaaaaat
    22501 tatatggtaa ttgaagatgt acaaaagctc aacagtgagg gagttataga tgaggatgat
    22561 gctattctcg attctgagaa gtatgtcgtt ctattgaagt caagtttgaa ttatgtagct
    22621 gatctaccag aaaaatttaa agagaagcta ttagcaggtg tccgttttat ggatagtagt
    22681 ggtcaattat tagttattcc ggatgatcct aatgtgtttg aatcagaagt tgaagaagct
    22741 acagacttct atagcgcagt agagcaatta gaagtagcta ctaatggatt agaacgaatt
    22801 gctgagacct tcaactcttc tgaagaagtt gaatttgaag ccgtagcaga aaatgtacca
    22861 gatgaaaaag aagctctttt tgtggatgat aacaaaccaa ccgaagcaga aaaccaagaa
    22921 gtaagcatag aagaaacaca aatacaaaca gaaacctacc aacaaccaaa aattgatgaa
    22981 aaacccgaat cccaaagtga caaagaaaat tatgtttatg aagctgaaaa aatcacatct
    23041 gaaagtgatg taccgaaaaa cttagatgct gattttttag aaaaaaattt tgaacagatc
    23101 attgctgaca aatttcaacc tgtagtttta gatgagatta atgaccctgt cgatttaaac
    23161 gaggagatgc tatccatacc tgagttgaaa ccattgctgt ttttagctaa agagagtatg
    23221 aacgctcgca tctctattgc taataataaa atcaacagtg aattaaataa gacgaaggag
    23281 caattgatcc tcaaaggaaa gcaaatgtta gctgatgagc ttttgcggat agaggaagca
    23341 acctcattaa atggtcaaaa tcagtttaca aatacactat cggttgctaa agagagctac
    23401 gaagcagaag catctaaaat tgatgattta gtgatggaaa aatccaatat cattcgtaaa
    23461 gattatgata tggcgaaaca ggcttatttg gatgctgaac taaagaaact agagcaacgg
    23521 tatgatgctg agcatttacc agaagttaaa caacaagaag atgaatatag aaaagcaact
    23581 gaagaaagtc ttgatcaaca gtaccaagaa gcaattgaat ctattaaaaa cgatgcattg
    23641 aaacaaagcc aagaagcaaa agaagttgtg gtggaacgaa ttatcaattc attgaaacca
    23701 gaaattgaaa aatcattaac agacgtgcaa gaaaaaactt tagagattgt cgaaaaaaca
    23761 aagtcagaaa atgaagctga gttccatgat acaaaagaga aaacaacaga tgtggttgtc
    23821 aaatattttg cgaacaaaga agaagttgaa aagcaggtag ctaacaacac gaaagaatta
    23881 gaaacaaaac ttgtagagca acaaaaaact atcgaagaat ataaagatcg aatgaaagag
    23941 gtcaaagatt tagcagaggg ttataaatta aatagcgaaa agttggcaga acaaagtgaa
    24001 gctttaagag aagacttatc tcgttcccga agtgatctag ctcaaatggc agaaaaaacg
    24061 aaatcattag cagttgctac agaaaatcaa tcaagttcaa aacgtgattt tacaagtaaa
    24121 aagatggcta ctatcatttc tgtcgctgca atggcttgcg gaacgatctt gggatcgtcc
    24181 tactttatta gtcataataa tcaacaagca caggctcaaa ctcaaacatc tatttcgaga
    24241 gtggaaaatt cgattgggac aaatacgaac tctgcttcaa caaatagtag ctatgaagca
    24301 acaccaacta cagagttcaa agttgggaaa gatgttgtca tcagtattga tgggaaaaca
    24361 actaaggctg aagtgatttc tattgatgga gaaaaagcag ttgtgaaaac tccagacgga
    24421 aatcagtaca aaattcaagc tcacttatct gataataact aaggagggct attatgcgag
    24481 aagaaaaaat agtttatcca gtaattcaaa acaatcaaga aaacatgacc tcttctcagc
    24541 acttacagga agcacagctc gtgtatcagg taaatgaact accacaaacg aacgagacaa
    24601 tgagcaagtc aatatcttta attggcttgc ttattgttgc aatagtgata actgtaggtg
    24661 tttaccgtaa gttgaacgtg aaaggaagta tttctgatgg cagataactc aaactatgga
    24721 tttaaacata acttacatca aaaaccttct gaaacaattg tcagagttga atggcttgaa
    24781 aagcatgtca atagcaccta ttctgttaca gcaaaaagat taattgtatc agctatagtt
    24841 gttgcagtcg ttgttcttgg atcaattgtt tacttagttt ctgatacgat taaactgaaa
    24901 tttatttttg ttccaacgtt attaatgata attggatttc ttattctaat tagccagtat
    24961 atgtttattg atccatctag tggttcattg atttctggtt ctattagact gttcaaatca
    25021 gtagttaatt cagcaagagt atctatgggg aaaaagaaac catttcgagg cacagagatt
    25081 ttaaaagtga aacaagatgg aacaatcgta tatcgagatg ggagtgtagc attaatgttc
    25141 aatctagatg gggctacatc actaaccgct tttccagaag aagttatggc tcaggaatcg
    25201 aaatcaatac aatatcaaaa taccagagat cgttccttag ctgaaatcaa aatcacttca
    25261 tctcaacctc agaatacgga aagacaaact cgaaatatga aaatacaaaa acgaaatgca
    25321 aggagtaaca aagcagtctt tgacataata gatcagcaag aacgatttgt atcagaatat
    25381 attgatggtg tgaaaacaac agtaatccaa tatcttatct tgaaatctca atctaagatg
    25441 gtattggatg aaggtgtgga acgtttagaa aactatacga gtagaggact ttattatagt
    25501 gtcactcagt tgtcagctaa acaaacaaaa gaaatattat ctgatattta tgcactgaaa
    25561 tagaggtgag agattaaatg gaaattatgg gtagatcaca actattaaat ttcaaaaaaa
    25621 agagaaaaac taaaaaagaa caaaaaacta gaaattcaaa ggtagtgaat aatacctttg
    25681 ttagtgattt aacatcttta gttggttatc aatttacacc atcttacatt aggacaggta
    25741 agcggtgggg aacaattgtg aaattagtga atacttatgg aatgaataga aattatggat
    25801 ttggttggat ggttaaagct attcctgaag tgagagtaga aggggtaaaa gcctatctaa
    25861 ttgaagcaga taagccagtg tcacaaaaag atcaacaaga aataatgcac gagaatgttg
    25921 ggggatcaac gaatagttat gaaaataatt tagaaggaaa aaattcagat gctgaaatta
    25981 gcaaaactgt tatgcggatt atggatttga atacagcatc tttactagac agcatggcaa
    26041 ataaaattat tgattggaag ctagaaatcc tattagtatc cgattctcct aataaaatca
    26101 gcgaacagct aattaaactc caacggttgt atgatgaaaa aatgtatgga ttaaagctta
    26161 tgtcatatgg aggagatcaa cgtgatctgt ttgatagact tttaagtgaa ccaatcggga
    26221 atgtctatga gtatacgtct atgagttcgg attttgcagg aaatgatcat gcaattcgca
    26281 aaggtttaga tgatgcgaat ggatgggcta tcggcactat gtctactagc tacgcaagtg
    26341 gtgtagcttt tatggcactg gatgattctt ttacaagtaa agttttagtg gcatcacaca
    26401 aaaacgctac aattaaaggc tatgatgaaa aaatctcagc atcatcactt tgggggcaat
    26461 tgattgctaa taatgcaatg gcaaatcata aacgaacttt tcatattgtc ttaaataaat
    26521 ttgattactt tggtgatcca actggtagaa catttgttgc caaaccttcg ttaaacagtg
    26581 taatagaaaa ggttaatttg gctgaagaag gtcttaactc tttggagctt tttggtaatc
    26641 aaaaggacat tggtgattta tatagacgga atctcgataa actaactcag attttttatt
    26701 tgttagcagg cagaacatta gattctgcaa ctagagtttt attgaaaaaa gaattaggta
    26761 acttttatat aagtcagaaa ctttgggata ttaattatga agaacgttca aaacttttgg
    26821 tgaacagtag tgatacaatg ccagttcttg gggattttat tagctatttg actaatgctg
    26881 aaacaaaagc caaaaaatct ggtactgaaa aagaagtcga tcgtattatt gtattaaaag
    26941 acacattgag aacagcatta gacagcttct ctaggatgtt taatcaaaga acgacactga
    27001 aagaaatcgg taaaagtgac aaattacagt tttactataa cttaggtgat ctaagagcag
    27061 aaaccaatgt tatggaagct caatttttaa atacctttga tttcatcaca tcacaagcaa
    27121 aaaaagatga tattgttatg attcacggct tcgataagtt atctattgaa accgttgggc
    27181 taattaaaaa aagattaaca atgcttgaag aagatggaat tcgtcttgcc tttctatttg
    27241 atacaatcgg ttcaggagaa gacaatgaat acaaagaaga tattgaaaca gctgatatat
    27301 tcaatacaga tggaaaaatt taccaaagtt ttgaaagtga ttttaattac actatcattg
    27361 gaaagatgac cagtggagag ttaatgaagt atgaaaaaaa agttgctcct gctagaaaag
    27421 gagaagatga tcaaaaactt tctgttgatt tgagacagta tttgacaaca ggaagaagta
    27481 ataaatttca gatcaggaga ccagtggatc tgactaataa ttttgttatt ggagagttta
    27541 ttctttaagt tttatctttg attttgagtg tataaggaaa ggataagaaa aaacatgtat
    27601 atttgagact aaaaacagtc ttagagaaca tggtacgttt tgtgaaaaga gaactataga
    27661 aatttcataa agtgaaacct tattgagtga aataattata gtggaggtta aataatgaaa
    27721 ccaaacataa aaattttaga tcgaatattt ctaggtagag acacagaagt aatcctaatt
    27781 caacatgaag aaggatttga agttagtata ggtattcaga aacttcaaaa acctcattat
    27841 tgtaatcagt tgtataaaaa ctttactgat gaagaaaaag cgagagtttt ttttaatgaa
    27901 gtcaaaggta tgagagaaca gtatgaggtg gttgaagcat gaataagtta ccagaaaaga
    27961 accgtgtatt tagattgaaa ggtgatctca gtca
//
LOCUS       DAFELK010000035        27928 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFELK010000035
VERSION     DAFELK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.036"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            2..77
                     /locus_tag="LP433_001795"
     tRNA            2..77
                     /locus_tag="LP433_001795"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            79..149
                     /locus_tag="LP433_001796"
     tRNA            79..149
                     /locus_tag="LP433_001796"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Gly,seq:tcc)
     gene            163..236
                     /locus_tag="LP433_001797"
     tRNA            163..236
                     /locus_tag="LP433_001797"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:197..199,aa:Ile,seq:gat)
     gene            261..348
                     /locus_tag="LP433_001798"
     tRNA            261..348
                     /locus_tag="LP433_001798"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Ser,seq:gct)
     gene            370..441
                     /locus_tag="LP433_001799"
     tRNA            370..441
                     /locus_tag="LP433_001799"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:403..405,aa:Glu,seq:ttc)
     gene            464..553
                     /locus_tag="LP433_001800"
     tRNA            464..553
                     /locus_tag="LP433_001800"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:500..502,aa:Ser,seq:tga)
     gene            566..639
                     /locus_tag="LP433_001801"
     tRNA            566..639
                     /locus_tag="LP433_001801"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:600..602,aa:Met,seq:cat)
     gene            658..730
                     /locus_tag="LP433_001802"
     tRNA            658..730
                     /locus_tag="LP433_001802"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:Asp,seq:gtc)
     gene            734..806
                     /locus_tag="LP433_001803"
     tRNA            734..806
                     /locus_tag="LP433_001803"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:767..769,aa:Phe,seq:gaa)
     gene            811..881
                     /locus_tag="LP433_001804"
     tRNA            811..881
                     /locus_tag="LP433_001804"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Gly,seq:tcc)
     gene            894..967
                     /locus_tag="LP433_001805"
     tRNA            894..967
                     /locus_tag="LP433_001805"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:928..930,aa:Ile,seq:gat)
     gene            979..1050
                     /locus_tag="LP433_001806"
     tRNA            979..1050
                     /locus_tag="LP433_001806"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1012..1014,aa:Glu,seq:ttc)
     regulatory      1239..1318
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1316..2509
                     /locus_tag="LP433_001807"
     CDS             1316..2509
                     /locus_tag="LP433_001807"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBL2005959.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            2639..4111
                     /locus_tag="LP433_001808"
     CDS             2639..4111
                     /locus_tag="LP433_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2005960.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4194..4982
                     /locus_tag="LP433_001809"
     CDS             4194..4982
                     /locus_tag="LP433_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBL2005961.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5049..5717)
                     /locus_tag="LP433_001810"
     CDS             complement(5049..5717)
                     /locus_tag="LP433_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBL2005962.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5832..7544
                     /locus_tag="LP433_001811"
     CDS             5832..7544
                     /locus_tag="LP433_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005963.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            7547..9316
                     /locus_tag="LP433_001812"
     CDS             7547..9316
                     /locus_tag="LP433_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005964.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(9521..10087)
                     /locus_tag="LP433_001813"
     CDS             complement(9521..10087)
                     /locus_tag="LP433_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2005965.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(10087..11043)
                     /locus_tag="LP433_001814"
     CDS             complement(10087..11043)
                     /locus_tag="LP433_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBL2005966.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(11043..11699)
                     /locus_tag="LP433_001815"
     CDS             complement(11043..11699)
                     /locus_tag="LP433_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL2005967.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            12069..14087
                     /locus_tag="LP433_001816"
     CDS             12069..14087
                     /locus_tag="LP433_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2005968.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    14157..14363
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            14514..16928
                     /locus_tag="LP433_001817"
     CDS             14514..16928
                     /locus_tag="LP433_001817"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBL2005969.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            17276..18829
                     /locus_tag="LP433_001818"
     CDS             17276..18829
                     /locus_tag="LP433_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL2005970.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(19210..20994)
                     /locus_tag="LP433_001819"
     CDS             complement(19210..20994)
                     /locus_tag="LP433_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005971.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(21009..22730)
                     /locus_tag="LP433_001820"
     CDS             complement(21009..22730)
                     /locus_tag="LP433_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2005972.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            22830..23591
                     /locus_tag="LP433_001821"
     CDS             22830..23591
                     /locus_tag="LP433_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2005973.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            24558..24826
                     /locus_tag="LP433_001822"
                     /pseudo
     CDS             24558..24826
                     /locus_tag="LP433_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            25498..>27928
                     /locus_tag="LP433_001823"
     CDS             25498..>27928
                     /locus_tag="LP433_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005974.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEFEIERSQTAVVELTKE
                     NRLTPGGVVLTK"
BASE COUNT         8867 a         4955 c         5884 g         8222 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgccatgc gggtgtagtt tagtggtaaa accacagcct tccaagctgt
      121 tgtcgcgagt tcgattctcg tcacccgctt ttagtttttt atgggcctat agctcagctg
      181 gttagagcgc acgcctgata agcgtgaggt cgatggttcg agtccattta ggcccattag
      241 tacaaaatct tattggtttt ggggaagtac tcaagtggct gaagaggcgc ccctgctaag
      301 ggtgtaggtc gggaaaccgg cgcgagggtt caaatccctc cttctccgtt tcaatatttt
      361 gttttacctg gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg
      421 gttcgaatcc cgtacgggtc attaatttaa tatagtttta catggaggat tacccaagtc
      481 cggctgaagg gaacggtctt gaaaaccgtc aggcgggtaa aaccgtgcaa gggttcgaat
      541 cccttatcct cctttttcat attatcgcgg gatggagcag tctggtagct cgtcgggctc
      601 ataacccgaa ggtcgtaggt tcaaatcctg ctcccgcaat taaaaactaa aaacattggt
      661 tccgtggtgt aggggttaac atgcctgcct gtcacgcagg agatcgcggg ttcgattccc
      721 gtcggaaccg tttggctcgg tagctcagtt ggtagagcaa tggattgaag ctccatgtgt
      781 cggcagttcg attctgtccc gcgccattat gcgggtgtag tttagtggta aaaccacagc
      841 cttccaagct gttgtcgcga gttcgattct cgtcacccgc ttttagtttt tatgggccta
      901 tagctcagct ggttagagcg cacgcctgat aagcgtgagg tcgatggttc gagtccattt
      961 aggcccattt attttattgg cccgttggtc aagcggttaa gacaccgccc tttcacggcg
     1021 gtaacacggg ttcgaatccc gtacgggtca tggaagatac tttttgagta tctttttctt
     1081 tttatctgaa agaatgattt taaaaagctt agcagagtta tctttatgga tgattgtgct
     1141 aagctttttt ggacagttct aatgtaaaat atttttatat tttttaagca aaaaaatgaa
     1201 aaaatacgag cagaaaactg ttttatctgc tatacttggt tcgttgcaag ttcccgaaag
     1261 gatccgcagg acggagatgc cttgtaaccg aatttaacta gggggaatca ttataatggt
     1321 agaaagacac ttatttacat cagaatctgt ttctgaagga catccagata aaattgctga
     1381 ccaaatcagt gatgcaatct tggatgcaat tttaaaacaa gatccaacag cacgagtagc
     1441 gtgtgaaacg tctgtaacaa ctggtcttgt tttagtattt ggagaaatat ctacgacggc
     1501 atatgtagat attcaaaaag tcgtacggga aacaataaaa gaaattggtt atacacgtgc
     1561 aaaattcgga tttgatggag atacagcagc tgtattggtt gcgattgatg aacaatctcc
     1621 tgatattgct caaggagttg atgaagcact tgagatccgg gatgaagata aaaaagacgt
     1681 attagatgag attggtgctg gtgaccaagg tttaatgttt gggtttgctg tagatgaaac
     1741 accagaattg atgcctttac caatcgcttt gagtcatcgt ctggtacgac gcttggcaga
     1801 tttgcgtaaa tcaaatgaat taacgtattt acgtccagat gcaaaatctc aagtaacggt
     1861 tgaatatgat gatcaaggac aaccggaacg cgtagataca atcgttattt caacacagca
     1921 tgatgatgca gtagataatg aaacaattcg tcatgatgtc atcgaaaaag tagtgaagga
     1981 agttattcca gctgaattat tagatgatca aacgaaatat tatatcaatc cgactggccg
     2041 atttgtcatt ggtggtcctc aaggggatgc cggattaaca ggaagaaaaa tcattgttga
     2101 tacgtatggc ggttatgctc gtcatggtgg cggtgctttt tctggtaaag atgcgacaaa
     2161 agttgaccgt tctgccagct atgctgcacg ttatattgct aaaaacattg ttgcagcagg
     2221 gcttgctcgc aaagcagaag tacagctagc ttatgcgatt ggtgttgctc aacctgtttc
     2281 gatctcaatc aatactttcg gtactggaac ggttccggaa gaagaactga ttgctgcagt
     2341 gagagaaaac ttcgatcttc ggccagcagg aatcatcgag atgcttgatt tgcgtcgtcc
     2401 gatttacaaa caaacagctg cttacggtca ttttggtcgt acagatgtag atttgccttg
     2461 ggaacatacg gacaaagtag atgcgttgaa agcaagttta gcaaaataag ttatattcag
     2521 ctggaacgat cgccaagtgg tggttgttcc agcttttttt atggcagtta acctcttgaa
     2581 aaagatagta attatttatc tatttttaga tcctgtcata atgaaaggga ggaataagat
     2641 gaaaaaagaa acaaatgtta ctttggtcac agtgagtatt ttcattgcaa cgttcatgac
     2701 ggctattgaa ggtacaatcg taacaaccgc tatgccaacg attgtcggtt cattacatgg
     2761 aatggaaatc atgaactggg tattttcgat ttatttgctg acaaacgcta tgcttactcc
     2821 gatttacgga aaacttgcgg ataaagtggg acggaaacca atctttattt ttgggacatt
     2881 attgtttatt atcggttcgt tattttgcgg tttatctcaa agcatgattg ggttgattgc
     2941 tgctcgtgcg attcaaggga tgggtgctgg ggcaatgatg ccagtagctt tgacgatcat
     3001 cggcgatctt tattctattg aaaagcgagc aaaagtttta ggtttgaata gttcagcctg
     3061 ggggattgcc agtgtttttg gaccgcttgc gggaggattc atcgttgaaa cgatcagctg
     3121 gcactggatc ttttttatca atgtgccgat cggaattcta ttaattattt tgatttggct
     3181 atatttaaat gaaccaaaaa tcatacatga gtctaaacca atggatattt ttggtagttt
     3241 tagtttgatg gccatgcttg tctcattgct gttagggttc caattattag gagacgaagg
     3301 aatgagtccg cttgtttctg ctttgctgct aggtagtatc gtaatgttag gtatttttgt
     3361 ttttgccgaa aaaagagcta aagatcctgt catcatgatg catttattca aaaatccact
     3421 atttgttgtg gtcaacttgg ctgcagcatt ggctagtggt tttttgatgg gaatcgatgt
     3481 ttatatccct atgtggatgc aaggtgtatt agggctgaat gcagcaattg gtgggctggt
     3541 attagcacca ttatcactag tctggatggt cggttctttc cttgcaagca agtggatgac
     3601 tcaaatgaaa actcattggg tcttgagaat tggactacta atcgcagcta ttgggggcgc
     3661 ttggttgtat cttatgcctt tcagaagtaa ctatttatgg ttttttgcta tatcaacggt
     3721 catcggtata ggcttaggtg tgaccatgac tacctcgact gtcagtgcac aaaatagtgt
     3781 atctcgtgac cagcttggtg tagcaacttc ttttaatacg ttagttcgaa caattggtca
     3841 aacagtcatg gtttctattt ttggtttatt gataaatggg gtaactaaac gagaacttgc
     3901 agcagcaaat ttaacaaatg atgcagatat catgaataaa ctggtgaatc cacaaacggc
     3961 taaatatatt gatgcggata ttttgttacc attaagaaaa attctttatg atgggttaca
     4021 ttccgtttat ctagttggct tgttactcgt gatcattgct ttggtcttaa cgcttttcgt
     4081 tcatgaaaaa agtggtaaaa taaaacagta gtttcggtta agatatgtac gtagccgaat
     4141 cattcaaatt taaagttatt caaaaataac ttcttactaa ggaaggcgaa aatatggcat
     4201 ttattcaagc aaatatttat tcgaatgtgt tagaaatgga agtcaatcta aatgtgatac
     4261 taccgcaaac aacaaaaaag gtgattggca ccagttcaga gcaagagaca acggatatac
     4321 ctgttttata tttacttcat ggaatgggtg gcaatcatag tgtatgggaa agacgtacgt
     4381 cgattgaacg ttatgtagca aactacggat tagctgtcat catgccatct actgatcttg
     4441 gctggtacac agatacagtt tatgacatga agtattggac attcattgca gaagagctac
     4501 ctgagatttg tcatgaatta ttcccgcaat taacaagaaa aagagaaaaa acatatgccg
     4561 ctggattatc gatgggcgga tatggcgcgt taaaactagg ccttgcaaaa tcagaaaatt
     4621 tcgcagcagt aatctctctt tcaggcgctg tttctgtagg aaatcgaatg gatgatcttt
     4681 tgatggttcg taaagcatct ttttgggaag ggatctttgg accattggat caaatcgaag
     4741 gttcaaaaaa tgatccgcaa tacttattga aagaactagt aaaaagcgga aaaccagttc
     4801 caagatttta tatggcttgt ggggaatctg attttcttta tcaggcaaat caggaaatgg
     4861 tatctgctat gcaggaacaa ggcttggcgg tcacctttga acaaggacct ggcgatcata
     4921 actggatctt ctgggaccaa tggattcaac gtgcattggc gtggctaatg gaagaaaaat
     4981 aaaaaaagag tcttaaaaag atagctccta tagagatcac aaacatagtg atctctatag
     5041 gagctttttt actgctcgtt ttctcttctt ttattttgtt ggcataagcc ttcaatatag
     5101 gtttgtgcac tcgttagaaa gagtgctttt tcattcaatt ctgcatggga ctgcatactt
     5161 tctttaaatc cctctaattg attttcaact acataattac gcataaatag aactgtttct
     5221 ttcaaaaatt catttccgtc cataattttt tgtcgaagct gctgttcatg ctgctgatcc
     5281 attaactgtc caatcaataa attgtggaga gaggcaatgg cctgatgact ttgggtgact
     5341 gaaaatcctt cacgaacaag taattggatc atttgctcca aatgttctaa tcgactcgga
     5401 aaagcgggca cagtattgat ttctaattct gccccacaag ggaaacgtgt ataaaggtca
     5461 tagtaatttt ccatatactg cagcaactgt tcattccaag gcaaagttgg atctggaagc
     5521 gctaattctt cttccattgt ttcagccatt atttgcaaga gctgttgttt gtttttgaaa
     5581 taccaatata aagcaggtgc ttgaacatga attctgtttg cgatgtttcg catggaaagc
     5641 tgcgaaagag cttgtgtttc agccaggata tcaaaggcgg cctgaatgat gattgcttga
     5701 gaaagcttta tttccatttt atcaacctcg tgtattgcat tatcttttta aacatggtaa
     5761 attgttagtc ggtctaattt tacagtgtta aattagtcct gtcaatttaa acaaaggggt
     5821 gtaatcaacg aatgaaatta atcttacgac atgcgaaaaa atataaagta gctgttttta
     5881 tttccttgct gtccgtagca gtcatggttg cagcagcatt atggcaacct aagttactac
     5941 agcaagtatt ggaagctatt attacagaag ataatgatga aatgaaaaca attggtattt
     6001 acctgatcag tctggctttg ctaggattag ccgcaggtgt aacgaacacg attttctctg
     6061 caaaagtagc tcaaggcgta agtgcagata tccgagaaga agcatttcga aagatccaga
     6121 cattttcatt tggaaatatc gaacagttct ctgctggaaa tcttgttgtt cgtctaacaa
     6181 atgatatcac gcaaatccaa aatttagtga tgatttcttt gcaatcactt tttcgaattc
     6241 cattcttatt tattggtgcc ttcattttag ctatgatcac gatgccgcaa ttatggtgga
     6301 tcatcgtagc gcttatcgtt acggtatttc tgattacggc actttcattt acaaggatgg
     6361 gcaagcactt catgatcatt caaaaactga ttgatcgtgt gaatagcatt gcaaaagaaa
     6421 acttactagg gattcgtgta gtgaaatctt ttgtacaaga agaaaaccaa ttgaagtcat
     6481 tcagcaaagt aagtgaggac ttaacaaaac acaacatcat agtcggtaca ttattttctg
     6541 tgatgatccc gtccttcatg ctggctgcca atttggctgt ggttggggcg atcttttttg
     6601 tgagcgatct tgttaaagat gatcctacgt taattggtgg aattgcttca ttcatgaact
     6661 acttgatgca gattatgatg gcaatcatta ttggcggaat gatgatgatg atgacttcaa
     6721 gagcagccgt atcgctgaag cggattgcgg aaattttaga tgctgaacca gatcttactt
     6781 atttagacgt tccagaacaa gagttgacgg gttctgtcac ttttgaccat gtttcttttc
     6841 gttatcctgg tgaggataca gatacgctta aagatatcag cttttctatc aaacctggag
     6901 aaatggttgg tatcgtcggg gcgactggtg ccgggaagtc aacactagca caattgatcc
     6961 ctcgtctatt tgatccgaca gaaggcaaag ttgaagtagg tggtgtagat cttcgtcaag
     7021 taaatgaaaa gagtttaaga caaacggttt cctttgtttt gcaaaaagca attttattct
     7081 caggaacgat tgctcaaaac ttgcgccaag ggaaaaagaa tgcaacagaa aaagagatgg
     7141 aacatgcttc ttctattgct caagcaaaag aattcatcga aaagttatct gatcgttacg
     7201 aagcaccaat agaagaacgt agcagtaact tttctggtgg tcaaaagcaa cgtttatcca
     7261 ttactcgtgg cgttatcggt aatccaaaga tcttgatcct agatgacagt acgagtgcac
     7321 tggatgctcg ctctgaaaag ctggtccgag aagcactcga tcgagatttg aagggaacaa
     7381 cgacgattgt catcgcacaa aaaattgctt ctgttgtcaa agcagaccgc atcttagtat
     7441 tggatgaagg cagattagtc ggcgaaggaa cccatgagga attggtagct ggaaaccgtg
     7501 tctatcagga aatctttgaa actcaaaaag gaacggagga gtaagtatga ctgatctaat
     7561 aaaagcaagt aaatttttct atcactattt gaagcggtac aaactctcct ttttctttat
     7621 ctttatcaca gtgatcattg ctacctatct acaagtaaag gcacctcaat acatcgggga
     7681 agcttttcaa gaattagcta attacgtagg aggcttgatg caaggcgtag acgataaaag
     7741 caaatttgtt tctgtaatat ggaaactctt gctgttttat gtactagcta gtgcagccaa
     7801 ctttatctat agtattttgt tcacacaagt agtagggaag tcaacgaacc gaatgcgtat
     7861 cggtctattc aacaaattgg aaaaattgac gatccgtttc tttgattctc atcaagacgg
     7921 tgaaatttta agtcgtttta ccagtgactt agataatatt caaaatagtt tgaaccaagc
     7981 tttgcttcaa gtcatcacga atgctgtttt acttgtcggg atcttgatca tgatgttccg
     8041 ccaaaatgta gagttagctt gggctacaat tgcttccact ccagtagccg ttttgatagc
     8101 tgtcttgatt atccgcaaag cacggaaata tgtggatctt cagcaagatg aagtggggaa
     8161 actaaatggt tatatggatg aaaaaatcag cggacaacgt gtcatcatca caaatggctt
     8221 acaagaagaa acgattgaag gattcttaga gcataatcaa agtgttcgcg aagcaacctt
     8281 caaaggacaa gcttattctg gtctactatt tccgatgatg caaggaatgt cactggtcaa
     8341 tacagcgata gttatctttt tcggcggctg gttagcatta aatggtgatt tggaacgttc
     8401 ggtggcatta ggcttagttg tgacattcgt ccagtattca caacaatatt accaaccact
     8461 gatgcagatt tcatctggat acagcatgat ccaattagcg attacagggg caagacgatt
     8521 gaatgaaata tttgatgaaa aagatgaagt caaaccagaa aactgtaaag catttgatgg
     8581 tgttgaaaaa ggtcttgcgt tgcagcacgt agattttggt tattctccag aaaaactagt
     8641 cttgaaagat gtctcgatca atgtggacaa aggagaaatg gttgctcttg ttggtccaac
     8701 aggatcgggg aaaacgacga tcatgaatct gctaaaccgt ttttacgatg tcaatgatgg
     8761 ttcagtagtc atcgatggaa tagatatccg agattatgat cttgatgcat tacgtagaca
     8821 tgtaggaatc gttttgcaag aatctgtatt gttctccgga acgatcaaag acaatatcac
     8881 attcggcaaa ccggacgctt cagatgaaga agtcatcaat gcagcaaaac aagcgaatat
     8941 tcatgacttc atcatgacgt tagaaaaagg ttatgataca gagatatccg aagaaaataa
     9001 cttattcagt acaggtcaaa agcagttgat cagtattgct cgaacgatca tcacaaatcc
     9061 atctttattg attttggatg aagcaacaag taatgtagac acggtaacag aagcaaggat
     9121 ccaaaaagca atggatgaag caatcaaagg aagaaccagc tttgtgattg ctcaccggct
     9181 gaaaacaatc ttgaatgcag atagaatcgt tgtcttgcgt gatggggaag tcattgaaga
     9241 aggcagtcat cacgagttat tagcagaaaa tggattttat gcggaacttt atcataatca
     9301 atttgtattt gaataaagag gttgtgaaaa agctgtcctg catcaagtaa taagaacagc
     9361 caatcaaaaa cagcttctca tgtttttgat ttggttggac ttattaccgc agatataagc
     9421 ttttgagcac cgtgaataaa gaggttatga aatcaacgct ctaacctgag tattagagaa
     9481 aaaaacgcaa aacatatcat ttatgttttg cgttttttat ttatcttttt ttctcaatac
     9541 aatataaaat aggcggctgg ttcttttggt tgataaaccg ataattcagc acattatatg
     9601 tttcctgtgg cagtttggaa caaaaagaat caaccatatc cagttctttt tctccacctt
     9661 catgaccata gtagacgaca aggatcaatc gtccgcgagg cacaagtcgt ttcaatattt
     9721 cttccatagc tgtgcgtgta gtctctggca tagtgatgat tgctttatca ctttttggga
     9781 gataccctag attgaaaatc cctgctttga gattttgttg ttcagctatc acttctccta
     9841 acgtttcgtg gccttgtaga aacaatgaga cacgttcttc taactgacgc tgttctagcc
     9901 tttcacgagt agcatcgatt gcttgttgct ggatatcaaa actatagaca tgaccagttt
     9961 ttccgatgtg ttctgctaga aaaaccgtat cgtggccatt gcccatcgtt gcatctacga
    10021 cgtgatcccc tggttgcaag atttcttgca gtaatgtatg gctgaaatgc aaagcagttt
    10081 gcaacatcag acgctcacct ttttccgtac atcatatttt ccttggaagc tatctctgcg
    10141 aagaagttct tcatcaattg cattcaagac ttcccatttt ttcaagctcc acattggtcc
    10201 aatcaaggaa tcccacggcg catcccctgt caaacgatgg atgatgatct cttttggtat
    10261 catttccagc tggtcgcaaa tgacattgac atagtcagga cggctcatta attgaaggcg
    10321 accttcatga tagtcccgca acattctcgt tttgcgcatc agatgcatca aatggagctt
    10381 gattccttgg atatctgaat ctaaaatggt gcgtctgaca ttttctttca tcatttctaa
    10441 actttcgcct ggtaatccgt tgatcaaatg cgtacaaaca cggatattat gtttgcgtaa
    10501 tttagccacg ccatctaaat aagtttgata atcatgtgct cggttgatca gttttgaagt
    10561 ttcttcaaaa gttgtttgca atccaagttc tacccataaa tacatccgct cgttcagttc
    10621 agcaaggtaa tcaactactt catctggcag acaatccggt cgtgtaccga ctgataatcc
    10681 tacgacacct ggtaaattga ctacttgctc aaatcgttct ttgattattt caactggcgc
    10741 atgggtgttt gtaaaatttt ggaaataaac gatgtattgt tggacatgag gccatttttg
    10801 atgcatcatg tcgatttctt tctggaattg gattggaaga gggtcttcag gtgcaacgat
    10861 catgtctccc gaaccagata cactgcaaaa agtacaaccg ccatgggcaa cagtcccatc
    10921 tcgattcgga cagtcaaatc ctccatcgat cggcaccttg aaaattttcc cgccaaactc
    10981 atttcgtaaa gcgtaattcc aagaatgata tcttttattt ccttctgaat aaggaaaagt
    11041 cattaaaagt ccttctttct gtaagagtta tctatttgtt ttcttttttc tctatacact
    11101 ggataagtca ggcacagcca agaaagactg agtaagtaac cgccgatgat atcagtagga
    11161 aaatgaacgc ccagataaat gcggcttatc ccgacactta ctataataaa catcatcagc
    11221 aattgaagca atgtgcgtaa ggttcttttt tgaacaaaag ctggaagcag aaatagtaaa
    11281 gaaccgtaaa gaatcatact gcctgctgca tgtccactag ggaaactgta acttgtttca
    11341 actactaagt gcgccaatga aggacgctct cgcatgaaaa atagtttgat caccgggttg
    11401 atgattccag caattacaat aaatccagaa acgaaccaaa atgtttctgc cctttttttc
    11461 ttataccaca tccataaagc cgcacaagca aataaaatga tgacggtaag aggattaccg
    11521 aatttagtca taaagagttg gtagctgttc agatcaggat aagaagctct gacaatgcct
    11581 gtaaaccact gatcgaaacc agaaagccac gacagatgga actttacgat ccagcccaaa
    11641 atgaaaaaca ggacaagaaa gaagctacca gccacctgaa atgatgtttt atatttcata
    11701 caattcctcc tttgaagcaa tgacttatta tagcattttt ggtccagcga aaaaaacggt
    11761 aaagagataa aaccaatgta tgattcctct ttgaataacc aatattctta taaaaaaaat
    11821 aactgtaatc ggaaagacat tttttggtaa tgcaaatgaa atgttaggga aataaaatca
    11881 gtgtttttcg aaatcctttt aaacaagaac gtagacgtag gaagaacttg aaaatgaaca
    11941 gaagttgttc attacggtaa attacaatat gattacaaaa aacaacaaag ctcttaaata
    12001 acttttaata aatattaaga gaagttataa ttattaataa tagataaatt gaagttggag
    12061 gatagaagat ggaaaacatt gcaagaaaag aacggagacg tttagaacag accaaacgtt
    12121 ttcgaaaagc aaaacgaggg gcagcaatcg tgggaactgc gatggtaggc tgttctgtcg
    12181 ctgccccatt agtacagccg gttcctgttc aagcggatga aacacctgtt cagttcggcg
    12241 caagaatcaa tacagcggca tttatcacag aaattgctac ttatgctcaa ccaatcgctc
    12301 aagccaacga tctatatgca tcagtgatga tcgcacaagc agttgtagaa agcggttggg
    12361 gcagtagtgc gttatctcaa gcaccttatt ataatctttt tgggataaaa ggcagctatc
    12421 aaggacaaac cgtctacatg gatacgcttg aatttttaaa taatcaatgg gtaaataaaa
    12481 aggagccttt ccgacaatat ccttcttttg ctgaatcttt caatgacaat gcctatgtac
    12541 ttagaaatac ttcatttggc aacggttatt actatgccgg tacttggaag agcaacacga
    12601 aatcctatac agatgcgaca gcttgtttga cagggcgtta tgcgactgat cctggttacg
    12661 caggcaaatt aaataatatc atcgcaactt acggattgac ccaatatgat acaccagcta
    12721 gcggaaacgc aggcggtgga gcgactacag gtggcaataa tactggaagt gcaggtagta
    12781 ctggcggttc aagcaattct ggtaatacaa actcaggttc agcaacttcg accacttata
    12841 ctgtccaatc tggtgattct gtttggggaa tctcaaataa attcggtatc acaatggatc
    12901 aattgatcca atggaacaac atccaaaaca atttcattta tccaggacaa aaactgacaa
    12961 tcaaaggtag ccaggaaaat ggctcttcga cgaataattc cggtaacaat accaattctt
    13021 caggaaatgc tggtacatca aacggaggac aaacaactgg tgcgaaatac actgttcaat
    13081 ctggtgattc tgtttggaag atctcaaatg atcacggaat tacgatggct caattgattg
    13141 aatggaacaa tatcaagaac aatttcgttt atccaggaca acagctaatc gtatcaaatg
    13201 gcggttcttc taatgctgga gcaaatactg gctcaaatac tgggaataca agtggctcta
    13261 gttcgtccag ctcaagttct tctaatacag cttcaggaac gaaatataca gttaaagccg
    13321 gagactctgt ttggagcgtc tcaaataaat acggaattac gatggctcag ctaatccaat
    13381 ggaacaatat ccaaaataac tttatctacc caggacaaca actgactgtt tcaaacagtg
    13441 gatcaacaaa cagcacgtca ggtaatacag gttcgtcaac caatacaaat aacagcagtt
    13501 cagttaatac tggcagcagt tcgtctcaag gcacttatac cgtgaaagca ggtgaatctg
    13561 tttggagcgt ggcaaataaa aacggcatca cgatggatca gttaatcgaa tggaataata
    13621 tcaaaaacaa cttcatttat ccaggacagc aattgatcgt taaaggtgga acttcggcaa
    13681 atacaaatac aggttcaact acttctgcag cgaaaccaaa tacaccgaat acgtctgcta
    13741 cgacaagtac atcatccact ggtaatacga tgtataccgt gaaagcgggc gagtcagttt
    13801 ggagcgtagc gaacaaacat catatcacga tggatcagtt aatcgaatgg aataatatca
    13861 aaaataattt catctatcca ggacagcaag tgattgtgaa gaaaggttca tctcaatcaa
    13921 caaaccaaca atcagttact ggttcgaaaa cctatactgt gaaatctgga gaatctgttt
    13981 ggagtgttgc tgacagtcat ggaattacaa tggctcaact aatcgaatgg aacaatatta
    14041 agaacaactt tatttatcca ggtcaaacgt tgattgtagc taaataaaat agctgttcga
    14101 agaaataacg attgaattcc acaaaaatat ttgttactat aaggctactt aaatatgaca
    14161 acacttgaaa aggaagtagt aaaaagactg aagtttcaga gagcgcatgg ctggtgagaa
    14221 tgtgcacgga tgcttttgaa ctcgcctttg agttgccctt gctgaatacc cgagtaagca
    14281 agcggcggtg acggccgtta caacgttcga ggccttttca ctaaggtaaa attaggtggt
    14341 accgcgtaga ttacgtccta taaaaagagc aatcttttta taggattttt ttatttcttt
    14401 tgtgaagttt gagaaaacaa agcaaaagga aataaaaata aacagattct gccggttttt
    14461 tcgttatatt tataatagaa acaagtgttt tcaatagaac aggaggacag caaatgagtt
    14521 acaatcataa agaaattgag aaaaaatggc aaaaatactg ggcaaaaacg aatactttca
    14581 acacccatga tgatcctgaa aagccaaaat tttacgcact ggatatgttt ccctatccat
    14641 ccggtcaagg gctacatgta gggcatcctg aaggttatac ggcaacggat atcctttcac
    14701 gtgtgaaaag aagtcaagga tacaacgtgc tgcatccaat ggggtgggat gcattcggtc
    14761 tgcctgctga acaatatgcg ctagatacag gaaacgatcc agctgagttt acccaaaaaa
    14821 atatcgaaac attccgacgc caaatcaatt ctttaggatt tagttatgac tggaatcgcg
    14881 aagtgaatac aactgatccg gagtattata aatggacaca atggatcttt acgaagcttt
    14941 atgaaaaagg tctagcttat gaagcagaag tagcggtaaa ctgggtacct gaattaggaa
    15001 cagttatttc aaatgaagaa gtgatcgatg ggaaaagtga acgtggtggc tatgatgtag
    15061 tcagaaaacc aatgcgccaa tggatgctga aaatcactgc ttatgctgat cgcttattgg
    15121 atgatctaga attagttgat tggccagaaa gcattaaaga aatgcaaaga aattggatcg
    15181 gtcgttcagt aggagcaaat attgaattta aagtggctgg tacggataaa tcctataccg
    15241 tatttacgac acgaccagat actctattcg gtgcaactta ctcggttctt gcacctgaac
    15301 tagatcttgt tagagaaatt acgacccctg aacaaaaagc tgctgtagaa gcttatatcg
    15361 aagagacagc taaaaaatca gatctaaaga gaacggatct tgcaaaagaa aaaacaggag
    15421 tatttactgg tgcttatgca atcaatccag ttaatggcaa ggaaatccca atctggatcg
    15481 ccgattatgt attatcttca tacggcacag gagccatcat ggctgttcca gcacatgatg
    15541 aacgtgactt tgaattcgct caaactttcg gactagaaat tcttccagtt atcgaaggtg
    15601 gagatgttga aaaagctgct tacacagaag atggtacgca catcaactct gaatttctag
    15661 acggcatgaa caaacaagaa gcaatcgata aaatgaatga atggctagaa gaaaatggcg
    15721 tagggaaaaa agaagtcagc tatcgcttac gtgactggct attctcccgt caacgttact
    15781 ggggtgaacc aatcccaatc atccattggg aggacggaac agtcacagct gtcccagaag
    15841 aagagctacc attacggttg cctaagacaa aaaacatcaa gccaagcggt actggagaat
    15901 ctccattagc aaatatcgag gagtgggtca atgtcgttga tcctgtaaca ggtaaaaaag
    15961 gccgtcgcga aacgaataca atgccacaat gggcaggaag ctcatggtat tacctgcgtt
    16021 atatcgaccc tcataacaaa aaagaactag cagattatga aaagttgaag cgttggctac
    16081 cagttgacat ctacattggt ggagcagaac atgcggtact tcatttacta tatgcacgat
    16141 tctggcataa attcttatac gatatcggtg ttgttcctac aaaagaacca ttccaaaaac
    16201 tatacaatca aggaatgatc ttaggcgaaa acaacgaaaa aatgtcaaaa tctcgtggta
    16261 atgtagtcaa tcctgatgat gtggtcgaaa cttacggtgc agatacactg cgcatgtacg
    16321 aaatgttcat ggggccatta gatgcttcga ttgcttggag cgaaaatggc ttagaaggaa
    16381 gccgtaaatt cttggatcgt gtatggcgtt tgatcgttga tgagaacaat aaaatgcgtg
    16441 accgtatcac tacattgaat gatggcaagc ttgataaagt gtatcatcaa acagtgaaaa
    16501 aagtgacaga agactatgaa aatcttcatt tcaatacagc aatctcccaa ttgatggtct
    16561 ttatcaatga agcctataaa gtggacgctc tgccttatga atatatcgaa ggatttgttc
    16621 aactactcgc accgattgct cctcacatgg gtgaagaact atgggcaatc cttggaaatg
    16681 atggtggtat ttcttacgca ccatggccaa catacgatga agcagcactt gttgaagacg
    16741 aagtagaagt tgttttccaa gtaaacggta aagttcgtgc gaaaagcaat gttccccgag
    16801 acttaggaaa agatgagcta gaaaaagcag cattagccaa tgaaatagtg caagaatata
    16861 ttgaaggcaa aacagtcaga aaagttattg cggtaccaaa caagttagtc aatatcgttg
    16921 ctaattaatt ggctctttgt caataaggac tgatgagttg tgcaaaatca aatctgggcc
    16981 agaatgaact tcattctgtc tcagattttt tgttatttca aattgattaa ttgattgatc
    17041 aaaaaggttt tgattttcat gttctcaaac acgttcaatg tctttttctt ctgaatggtc
    17101 ttgtaagaga tctctgtaat catcaaattt ttgtctatta atcttagtat tttttgatgt
    17161 ataaactacc tgaaattgag agtacatacc aaattcataa attttttatt agtgggacta
    17221 gtgattgtat ggattttgac gcataatgaa tgaagtatga gaaaaggaga gacaaatgga
    17281 tcaagaacta tttattatcg aagtattatc agctaaacaa aaaattatcg agaaagcgaa
    17341 aaaaagagcg aaaagaataa tgttcaagct tttaagctta gtatttttct ctggtttgct
    17401 ttttttcgga gctgtatcgt tcctatatcg ccatatgagt gcagtagtcc gttcagctga
    17461 agggatgcaa aaattaaata atttgtatca cttttcgtgg ggagttggcg gaataacaat
    17521 tgttgtgctt attgtttttc ttctacttat ttggctccgt taccatcaat tgtcgcgtca
    17581 tttcgatcaa tggcttagtc aaagagcaca acagttttta cataataaac caacttctca
    17641 agatgatgac tatctttatt ttgagaagac ttcgacgagt caagcttttc ggatacaaaa
    17701 aagtgattgc cagttattgc tgagatcact tgatgattta cctatctact taggcgaaag
    17761 caaatcaaaa ttcggaatga acacattcca tattttttta ctagaaaacg aacccagatg
    17821 ggaaaaaagc cagtcttcgc ctggtggata cctgacaact aagatgagta cattagtcac
    17881 tggttttttc ctcattcttt tagctggaac aatctattat gggagataca ctcagccaaa
    17941 aatgtcttct catataaatg ctgcttctca catgacaatg aactcaacta acgatacgca
    18001 tatacaaaag acaaatgaag ggttgttagc tgatcctaag caaaaggtaa atttgacaac
    18061 acaaaagata aatgatctca aacttgatac agagacgcac tctctctata tgacaacaga
    18121 tagtggtgct aattgggtat ttgtgccgat tgattcgcaa tggttgcgtt ttggcgaata
    18181 caccctgaca acggggctga ttcctgaagg ttattggatg gacaacacat atgatatttc
    18241 cgccgatttc tcatggttta tctattcttc tggggatgat gtacgtctgc tgacttcaag
    18301 agataatggt aaaacatggc aaacgtctat tatcacccaa tcagttcagc cgatacgtta
    18361 tcgaaaagcg gtattttatg gcaacgatgg tctatttatc tgtacatcag ccagtgggat
    18421 gtctgcagaa actttgtaca tttacactac tatggatggc ggaatcactt ggataaaaag
    18481 tggaagtaca atgatcaatc agccagtaca aaatgtcagc ttcgttacaa cttctttagg
    18541 ttttgtttcg acacgtgaaa gtttgtttta tacaaacaac ggaggacgct cattcaaaga
    18601 atcagttctg tcgattccgg aaaactatca gacagggggg atagatcttt ttcaatcacc
    18661 aaatgaagtt actcaaataa gcgcgaatac gttagagaca aaattttatt tgttgaaaaa
    18721 aggaccaatc gatgcaggga aaatgtttgc ctgcctcttc cgttcaactg ataacgggga
    18781 aacatggcaa ttcgttcagc aactatcgca agtagaacaa ggagattaaa gaagagagat
    18841 tgtgagcctg acgttcagca ccgagtcaca agaaacaaat tcaaaaaaca gcttctcata
    18901 tttgttgaat agtgtaactc gtgattcgga gttgacaaga gcaacaagaa gcgattttga
    18961 agtatagctt ctcgtatttt acaagatcgt gtcttattgc cgataggttg tctcttgaac
    19021 accgtttatt cgtaaaaagg gattgtgaca agtcttttgt cactacttac cgaacgaaac
    19081 tgaaggagct atccaaaaag tatcattagt attattcttt gtgtttctag tggcaccact
    19141 agtacattta aaaaagctat cgatcatgga ctaatcatac atgatcgata gctttttaga
    19201 taatgtttgt tacgctatct gaaattgact attataaaga ctggcataaa gcgttggtga
    19261 ttggagtagt tcagaatgtg ttcctttttc gacgatatcg ccattcttca ttacaaggat
    19321 catgtctgca ttttcaatcg ttgacaaacg gtgtgcaatc acaaaacttg tcctatcttt
    19381 tgtcacagct tccattgctt gctgaatcaa tgcttctgtt cgtgtatcta cgctagaagt
    19441 tgcttcatct aaaataacga caggaggatt cgctagaatg actcgagcaa ttgtcaataa
    19501 ttgttgctgt ccttgagata acgtgccgtt ttcgctagaa atgatcgtat catatccgtc
    19561 tggcagtgtt cgaataaagt gatcacattg tgcgatttca gccgcttcga taatttgttc
    19621 tcttgtggca tccattttcc cgtaggcgat attatcagct accgttcctt caaacagcca
    19681 ggtattttgt aaaaccatcc caaaagaacg acgtagttct ccacgtgaaa gcttggtaat
    19741 atcaagaccg tcgaattcga tctttccttt attcagttca taaaaacgca tcagcagatt
    19801 gactaaagtc gtttttcctg caccagttgg accaacgatc gctaccgttt gttttggctt
    19861 tactgaaaaa tcgacttgat tcatcaatat tttatctgat gtgtaaccaa actgtacatt
    19921 tttgaaagct atttttcctt tcggttgttc taaaagtctt gcatctggaa ggtctggaat
    19981 ttcatctgtt tcatctaata tctcaaatat cctatcgatt gctgccattg cggattggat
    20041 cgagttgatc acataagaag cggtagaaat tggttcagaa atctgattga tgtactgaag
    20101 ataagcttgt aagaagccga tcgtcacacc acctgataga acaagcatag caccgaatac
    20161 cgcacttatg atgaaggcga gttgattaat gaaacgaatg gccggataga tagcaaagtt
    20221 cataaattga gcacgtttaa aagcgttgta ttgcttttta tttacttcgt gtatagcagc
    20281 ttctgcatga gcttgctgat tgaatgtttt gaccactaga ttaccagcta agatttcttc
    20341 cattcgatta tttaaaacac ccagttcata ctgattctgt tcagaaatct gtttgttttt
    20401 gttcgcaatc ttagttgtaa caattgaact gccaacgatc agcaataaga cgagcaaagt
    20461 aagcttgctt tcgatataaa acagcatcag accagcagca gctattgtta cgacagaagt
    20521 aaaaaattga ttgatacctg tcaataacac ttgagaaagt tgattgagac cggtagttgt
    20581 ccgactaatg atgtcaccta cttgatgatt gtcaaaaaac gacatcggta atgttttgaa
    20641 tttttttgtg atttcttttc gcaccctcaa tgtgatcttt tcgcttaacg ctgccattgt
    20701 ccgttcctga ataaatgaag tgatgctgct taagactgaa cagccgatca gcaataagac
    20761 agggaacaac aatgcttgtt tgatatcact gaaagaaagc tgtccaatac ctgtttttct
    20821 tatttctgat aagagatcat cgatcccgat tcccatgatc aagggcatgg ctacgactaa
    20881 taggttcccg aataaactgc atagaaacaa tccgtaaaaa tatttatgtt caggtttgat
    20941 cattttccaa aaacgtatca aagcacgcgt gttcaacgtt tttttctttt ccatcgtatc
    21001 ccttctttct atattccttg tgattttgca aactcctgat aagtttggca attagacagt
    21061 agttcttcat gagtaccttg tccaacgatt tttccttcat ctaaaacaat gatgttatct
    21121 gcttgttgga ttgtactgag gcgttgagca acaatcacga gagttttctc cgacatgtgt
    21181 ttatgaaggg ctgctcttaa tgctgcatct gttttatagt ctaaagcgga gaaactatca
    21241 tcgaatacat agatctctgc tggtttgatc aacgctcgag caatacatat ccgctgtttc
    21301 tggccccctg aataattaga accgccttga gcaacaaagc tgtccaatcc gtcaggaagg
    21361 gtgtccacta gttcttctaa ttgagcgatc ttgatcgctt tagacaactc ttctgttgag
    21421 gcatattcat ttcccatctg caagttgctt aaaattgtcc cgctgaataa gaaagccttc
    21481 tgagggacat aactgatgtg ggagcggatc tgttcttgag tcatttgagt aagaggaata
    21541 ccaccaaggg ttacttttcc tatcgtaggg tcactaagtc tcaagagaag tttcgccaaa
    21601 ctactttttc cagatccggt cccgccaacg atcgctgttg tttttccttt aggtattgtg
    21661 aaatcaatat cttctagaac tggatcagag atttcagtat atttaaatgt gacatgttca
    21721 aaagcagctg catttgtctg atcaaaggtt ggttcagcta ctgttttgat cgtctcttcc
    21781 tcaatttcga tctctgcttg cagtatttct tctatccgtc gtaatgaggc aaacgattta
    21841 gggataatga ccaataccat agctgcgatc atcaagtaag caagtgtcag catagagtat
    21901 tcgactacag cagtcacgac accgatttgt aatgctcctt ctgctacaag atttccgcca
    21961 aaccacaaaa tagaagcata aacgattccc atgagcaaaa aagcaattgg agtgacccaa
    22021 gcaaatattc ggttcacttt gatcatttga ttagcatagt cagcaaagct cttattcgtt
    22081 cgcttttctt catatgattg attatcaaag gcacggatca tattaatccc agtaaagaat
    22141 tctctcaatg tgatggtgat ccgatccatt tttggctgga tactcaaaga taaaggtgcc
    22201 cctcgtttca tcagtcgata aacaatccat acataaaaaa caacagagat caatgtaacc
    22261 catgttagta atagagaata acgaaacatc atgagaatgg tgaaaacgca aataaccggt
    22321 gctggtaaga tcatttggca aaataaaaca atcatttgct ggacattatc gacatcattc
    22381 gtcattcttg tcaaaagaga tccagaacta aaacgactga tatccttcat tgacagctgt
    22441 tggaatttac ggaaatattt ctcccgcgtt tggaatccaa acctagcgga agccaatgct
    22501 gaaaagtaac tagaggcaac tgcagcgatt gttcctagaa acgctacaag cagcatttca
    22561 actccaattt tttttataac tgaggcttcg ccacttgcta tacctgtgtc gatcagcttt
    22621 gctactaatt ttggtacacc taatgtaccg gcgatttgta aacagatcat cacaaaggta
    22681 aggagagcga gtcctttgtt tttctgtaag aatgttttta agatagacat attattcctc
    22741 cttttttcct gatacttttc gattctatac cttcaagtaa cttgaaggtc aatagaaaaa
    22801 agaataaact gaaaaagagg tgagaaaaaa tgaaaaaaat gtatacgatt ggccaagtat
    22861 cggaactatt tgatttgcca aaatcaacga tccgctattg ggatgaacaa ggattaatcc
    22921 gttcaagtag acaagaagag aatgattatc gattgtttga tatcgatgat atttttatgc
    22981 tttatgatat cgttttttat agaaaattag atataccgat caaacagatg aagaatttat
    23041 atggaaaaac attgacggag ttatatgaga cacttgatga aacagaaaga agaatccata
    23101 aagaactggt ggtgatgaaa caaaaacaaa aagagataag ggagcaaaaa aaacagttga
    23161 aattgatgat cgatacaaac gaggaagaat ttcctgtaga agagatccct tttgactgta
    23221 tgatctcaac ggagtttgaa gatattgtgg aaatcaaaaa atttctacct aactattcaa
    23281 gctttgggat gatgagtatg ccagcttcca gttcacagac gatgtatgga ttttttatcg
    23341 accctagtga agtacattta tttactcaag acgtgatttg ggagaaaaaa gatacggctg
    23401 tttatcgtcg attcttattg aaatccgaga tgaaccatgc ggaacgtaat aatattttag
    23461 aaatcagaga aagaatgtat gaaaaaggat ggaaaacagg agaagtgatc ggccagtatc
    23521 tattgacgaa tacggatgaa aacaatatca gaactgaata ttatcatgca tggatagaaa
    23581 tgaaaaaata ggaaatatgt gtttaagata actcgaaaat gatggttgtt ttagttataa
    23641 agaaaaattt tctggttcga ttacgggttt aatgtggggg attattagtc gtggatagat
    23701 agaattttag ttttttagag gaaatatgtc tttaaaaatg gaatggttgc aattcttagc
    23761 gatatatacg atgtaattgt cctcttaaaa aagtatggaa aaataattgt attgggtgtt
    23821 atgtataatt catggtgaac tgagactaat gagaagaaaa attcatattg ttatgagtga
    23881 gattgtatca gatgagaatg ataaattaaa taggtgcata aaagcattac acttaaaata
    23941 cattgttgct tacattatta caatatgtta ataaggcaaa aataaataga tggattgaat
    24001 aaacatattt tttaatcaaa tagtccctac tgtgactttc ctcagctatc ggtgatacta
    24061 ccgatagcat ttttttgctt ataaaataat tataagtatt tagagatttt tcttctaaca
    24121 ttcttcaaac aagaaaaatc acaaaggtta ttgttatttt tatatattct ttttaagaat
    24181 gattattttt ttatagaaat tttaaaaaat aaaacacgtt attgatggat agttagtttg
    24241 ttatttggta atattataga agttgactgg tagtgattta tttttcgttg ttttataaaa
    24301 atgttatttt ttggaaaaat tcacaaatat gtaacgaatg tttttctgga atttgctgtg
    24361 ttaaaaagca gtatgactaa tataaatact attgtcattt atgcaatttt ttatggatag
    24421 taattttaga ggggaatcaa tgaaggaaga atagaaggga aaaatagttg caaatacgcc
    24481 agttagcaaa aatagcaata catcttcaag ctttaaaatt cgagagaatc atcttggtag
    24541 tggaatcaac tacaacaaaa ggattaaacc aattaataga tagaattacc aatggaaaaa
    24601 tagaaaaggt agttattcta tacaaaagtt gtttaattcg cttcggttat gaacttagtg
    24661 aaaccctttg caatatatgg tacagaatat agaaattatt gacattacag aaaatgatga
    24721 agatttaata cagattgtca ctatttgtag atacctttta caaggaaacc gagccaataa
    24781 agctaagaag atgattaagg agttgatgga agacgataca agttaagaaa gtaaaactac
    24841 gcccaaataa agagcaaaaa gagtaattgg acgtggaaaa tgcaagaaat gaaccatcga
    24901 ttcggtggac agtttattag taatgacggt ttgagaacat ccatgacgag aatgaaggaa
    24961 catcctaaat gcgtttagtt gaaccaagtg ccaaataata tggccaaata agcgatcagt
    25021 tatcgatgaa tcccaagtat tctaaactat atattcattt tgatgctaag cattgatata
    25081 tttttttggg attgatgaag gttaaccaat acagggactc actgatgaaa ttctagagtc
    25141 tgaccttggt atcaacgatt tagtgattgt ttctaatgga aaagtataaa agtatataag
    25201 tacattaaca aaataactat tagggttacg ctccagcttg tgcaaggcac tggcaggagg
    25261 aatcgtgaaa tcataattat ggttaagcca cacggacaac taaaagtcat acaaagctat
    25321 cgaatcaatc aacagaagac aatcggcaat cattagcttt gtttacagct tacattgcaa
    25381 cgcttgagtt gaaccgaaaa tacgagggag gtaacgcagc cattttgagt tggggaatct
    25441 ttttagaaaa ttatcgggta ccttgttgtt tagtcaaaat tataaggggg agtaatagtg
    25501 aggaacaaat ttcataaact gttaagtatg tttctagtta tgcttattgt gatcaatcaa
    25561 tttgggaaca taacggttct agctgagtct ttagcagaac agccagagcg ttcgctgacg
    25621 atcgaagttg atcaagagga ggctgctttg ggtgagcagt tccagttgcg agtcagagga
    25681 acaccagacc tgctaaatgc attggtcatt gataagagtg aggatttgat tgaaggggaa
    25741 gtgaagcaac tcaatgatta cgaacgtctg attacttatt cttcccagca ttcaggtaaa
    25801 tacgaattga ccgcaagaag cggtgatatt caatcaaata cggtctcaat agaaatcagt
    25861 gtaccagaag aaagcacaag tgagtctttt aatgtaccag aagaaagcac aagtgaatct
    25921 tttaatatac cagaagaaag cttaagtgaa tcttttaatg aagccagatc atctgagcca
    25981 tctataacgc aggaatctca gattgaaaga caagaggagc tcttgaatta tgacatcggc
    26041 atctctgctg agcgccccac tttgccgagc aggcatacac aaacgttaaa gggatacatt
    26101 caaggaggcg ctggcgatat tcttgaagaa tatggggaga tggtcgtacg agttcctaga
    26161 gcatcgattg gcttaattga gttcattaga gtggaggtcg ctgatgattc acctttaaag
    26221 ccactggcat tttaccaaga aggcacagac gttgtttttc catttacctt tgattatgaa
    26281 ggattaaatg aagccgctca gtcgtataca ttcagtatca cgtttgaagt tgctttcttt
    26341 caatcaggcg gtactgagcc aaataatgac tttcaagtga gtcttactta tgctgagcga
    26401 gcagcaaaca cggaattttc aattacgcct attccttcat caagacccat tttttcgaaa
    26461 ttatactatg gctctagaga aatcgacagc caaggaaatc ttgggaatct gctgattgac
    26521 gggcaagacg tgaccaacag taataaattt attttgcagg taaattatga aggatcacga
    26581 aaagacggtg tagtggttac cgatgtacta ccgcaaggaa caactttggc accgaatccg
    26641 actacatgga gttccactgg aaatagagaa cctatttcag gtggggttcg gatcgcagaa
    26701 gtaacgaatc caggtgaagc aaacgttaga actcattatg tttccgagga atttgtggac
    26761 aaagtatctt ttaataagga aacgaataca cttgttgtgg actttggtaa tctagcagag
    26821 ggtcaatcgt attttattga atatgctctt gaagtgaccg atgtcgactt gttcaatgaa
    26881 ggaagacaag aggatgggtt ttctcggaat cgagcgagta tgacctacaa taatcaggta
    26941 atgagccgag actaccgctt gagaatccct gaaagtaatc ttccggcaat ctctttaaga
    27001 aaaagtgtgg acaaaaatgt tatcaatctc aatgaaaatg aactaacgta tactctgcat
    27061 gtctcgatgt tttctggaac aagcaatacg cttgttattg aagatgtttt ggaagaaggc
    27121 atggaatttg tgtcatttct atcagatatt ccctctttca ttgatgccga agtcaataat
    27181 ggaatagttc gtttcagtgc gaataatacg attggtggtc cgacaagttt taccctctct
    27241 tttaaggtca atgtagaggc gtatgcggtc ggcgatcaaa ttttaaactt tgcaacgctt
    27301 gtgaatagtg acaatcgatt gaatacgagt actgtaagaa caaggaaaat cgatgggcgt
    27361 attaaagtaa ttaaaactga tgagaatggc caaaggctgg caggagcaaa atttgaaatt
    27421 ttatcaagcg attcacaagt gatacaagaa ggtataacgg cagaaaacgg agaattttta
    27481 agtgaaccgc ttcctgtagg tagctatcaa gtccgagaaa cagaagcacc ggaagggtat
    27541 cttttagatg cgacggtaca tgatgttttt ataaatgaat actccataga agaagtgacg
    27601 ttaaccattg aaaacatcct tgatacgggt ggtgttgaac taattaaaca tgctgaaggc
    27661 agtggtgaag tccttcaagg agctgttttt gagttacaga accgagaagg agaaacgcta
    27721 caaaccggtt taactacagg agaagatgga aaactggcaa ttgacggttt agcaccagga
    27781 gcatatcagc tggtagaaac tcaagcgcca atagggtatg aattagatgc gacaccaatc
    27841 gagtttgaga tcgaaagaag tcagacagcg gtggtagaat taacgaaaga aaaccgactt
    27901 acaccaggcg gtgtcgtgtt gacaaaga
//
LOCUS       DAFELK010000036        27688 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFELK010000036
VERSION     DAFELK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.037"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            211..1917
                     /gene="efbA"
                     /locus_tag="LP433_001824"
     CDS             211..1917
                     /gene="efbA"
                     /locus_tag="LP433_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBL2005975.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2075..2977)
                     /locus_tag="LP433_001825"
     CDS             complement(2075..2977)
                     /locus_tag="LP433_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2005976.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2974..3666)
                     /locus_tag="LP433_001826"
     CDS             complement(2974..3666)
                     /locus_tag="LP433_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBL2005977.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3709..4350)
                     /locus_tag="LP433_001827"
     CDS             complement(3709..4350)
                     /locus_tag="LP433_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2005978.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4388..4702)
                     /locus_tag="LP433_001828"
     CDS             complement(4388..4702)
                     /locus_tag="LP433_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005979.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4690..6042)
                     /locus_tag="LP433_001829"
                     /pseudo
     CDS             complement(4690..6042)
                     /locus_tag="LP433_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(6039..6971)
                     /locus_tag="LP433_001830"
     CDS             complement(6039..6971)
                     /locus_tag="LP433_001830"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBL2005980.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6968..7744)
                     /locus_tag="LP433_001831"
     CDS             complement(6968..7744)
                     /locus_tag="LP433_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBL2005981.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7798..10983)
                     /gene="carB"
                     /locus_tag="LP433_001832"
     CDS             complement(7798..10983)
                     /gene="carB"
                     /locus_tag="LP433_001832"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBL2005982.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10988..12064)
                     /gene="carA"
                     /locus_tag="LP433_001833"
     CDS             complement(10988..12064)
                     /gene="carA"
                     /locus_tag="LP433_001833"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBL2005983.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12069..13349)
                     /locus_tag="LP433_001834"
     CDS             complement(12069..13349)
                     /locus_tag="LP433_001834"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBL2005984.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13368..14294)
                     /locus_tag="LP433_001835"
     CDS             complement(13368..14294)
                     /locus_tag="LP433_001835"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBL2005985.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14307..15590)
                     /locus_tag="LP433_001836"
     CDS             complement(14307..15590)
                     /locus_tag="LP433_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBL2005986.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15604..16143)
                     /gene="pyrR"
                     /locus_tag="LP433_001837"
     CDS             complement(15604..16143)
                     /gene="pyrR"
                     /locus_tag="LP433_001837"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBL2005987.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16378..17289)
                     /locus_tag="LP433_001838"
     CDS             complement(16378..17289)
                     /locus_tag="LP433_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL2005988.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17286..17750)
                     /locus_tag="LP433_001839"
     CDS             complement(17286..17750)
                     /locus_tag="LP433_001839"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBL2005989.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17755..18453)
                     /locus_tag="LP433_001840"
     CDS             complement(17755..18453)
                     /locus_tag="LP433_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2005990.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18440..18826)
                     /locus_tag="LP433_001841"
     CDS             complement(18440..18826)
                     /locus_tag="LP433_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2005991.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18973..20643)
                     /locus_tag="LP433_001842"
     CDS             complement(18973..20643)
                     /locus_tag="LP433_001842"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBL2005992.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20826..21059
                     /locus_tag="LP433_001843"
     CDS             20826..21059
                     /locus_tag="LP433_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBL2005993.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21158..21589)
                     /locus_tag="LP433_001844"
     CDS             complement(21158..21589)
                     /locus_tag="LP433_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBL2005994.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21668..22081
                     /locus_tag="LP433_001845"
     CDS             21668..22081
                     /locus_tag="LP433_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBL2005995.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22119..23267)
                     /locus_tag="LP433_001846"
     CDS             complement(22119..23267)
                     /locus_tag="LP433_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL2005996.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23389..23985)
                     /locus_tag="LP433_001847"
     CDS             complement(23389..23985)
                     /locus_tag="LP433_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2005997.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24185..26827)
                     /gene="alaS"
                     /locus_tag="LP433_001848"
     CDS             complement(24185..26827)
                     /gene="alaS"
                     /locus_tag="LP433_001848"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBL2005998.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27215..27645
                     /locus_tag="LP433_001849"
                     /pseudo
     CDS             27215..27645
                     /locus_tag="LP433_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         7816 a         6100 c         4889 g         8883 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgataccta
       61 aaaatttgga tttcaacgat agaaacactg ttttttatgt aattagtcca agatttttct
      121 agacttttgc tttactattc ggccaaattg gtttttcttc tttttttcgt tataatgaat
      181 atacttatga aaagaaatga ggaatgaacc atgtcctttg atggtgtatt tacccacgcg
      241 atggtcaacg aattgcgtga aacgttacta tctggccgga tctcgaaaat ccatcagcct
      301 tatgaaaatg aaatcgtgct ggtgattcgt tcacgcggca aaaaccatcg attattatta
      361 tctgcgcacc caagttatgc tcgtgtacag attacccaaa tcgattatca gaatcctgat
      421 aatccgccta acttcgtgat gatgcttcga aaatatttgg atggcgctat tttagaagac
      481 atcgaacaaa tcgaaaatga tcgagtgatc catttccact ttgctaaacg aaacgagttg
      541 ggtgatctac aaaatatcat attgatcgtt gaattaatgg gacgtcatag tacgatcgtc
      601 ttagttaatc gagaaactgg aaaaatactg gatgcgatca aacacattgg aagctctcaa
      661 aacacttatc gttctttgct tcctggtgta gaatatgttg ctccgccaaa acaagaggtc
      721 ttgaacccat ttagctccga gaaagaaaaa atctttcagc ggctttccca aactgaacta
      781 gatccaaaag caatccaacg tcagtttcag ggaatcggtt tcgatatcgc tcaagagctg
      841 accaaaagat tactggaacg tcctaatgaa aagatggttg tatgggacga atttttctca
      901 gccatcagcc atcagcctat tcctactttt tacgaaacgg aaaataaaga ttttttcaca
      961 ccgattgctt atcaggtatt gtccgaacag gcatctgctg taacagctta tccaacactc
     1021 agtcaattat tagatagcta ttatcacgaa aaagcagaga aagatcgggc aaaacaacaa
     1081 ggcggagaac tgattcgaaa aatcgaaaat gaactaaaac gaaataaaaa taaattgaaa
     1141 aaacgtgaac aaacactcaa agaatccgaa aacgctgaga attaccgtag aaatggcgaa
     1201 ctacttacta cttttctgac acaagtacca cgcggcgcaa aagaagttgt tttacctaat
     1261 tattatgaag aagatcggcc aatcaaaata gcactagatc cggcattgac accaaatcaa
     1321 aatgcacaga aatatttcca tcgataccaa aagctgaaga acgctgttaa gctgattggc
     1381 gaacaaatcc aagaagccaa agatgaaatc caatatcttg aatctgtctt atctcaactg
     1441 gaaattgccg gcccaatgga tatcgaagca attaaagaag aattgacttc agaaggatac
     1501 ctgaaaaaga agaacttaaa aaaacaaaaa cgtaagaaac catctcagcc tgatcaatac
     1561 ttttcttctg acggaacgct cattcttgtt ggtaaaaaca atcttcaaaa tgaccagctg
     1621 acaatgaaga cagctaaaaa aaccgactat tggcttcatg caaaaaatat acccggttcg
     1681 cacgtcatca ttaaaagtga caagccctca gatgaaacaa ttacagaagc tgccgagtta
     1741 gctgcctatt tttcaaaata ccgatactct gcccaagtgc cggttgatct tgtacaggta
     1801 aagcatatcc gaaaaccaaa tggcgccaag cctggttatg ttatttatga aaaccaaaag
     1861 acgattatcg tgacaccaga agaagaaaaa attacagcta tgaaacaaaa caggtaatca
     1921 atgagtgttt ctagaatcat atttgcgtac tttcccacaa cagcaattag ttataaattg
     1981 tttgctacaa aaagaggagt tgtgacaaaa ttctgtcaca acccctcttt tttgatcaac
     2041 ggtgttcaat aaacagcgtt ctcatctgct tttcttagct ctgctggtcc agtaaccgag
     2101 taagctcttt gataaatctt tgagcgattt cactgagcgg acgtttcgcc gaataaatga
     2161 tataaaattc atttagttcg ccttctgcca aagggattaa ccgcaagtgc tcgcgaatcc
     2221 ctccaatcac aataccagat cctgaagcgt aagcatcagt ttcaagaacg atattcatca
     2281 aagtacctcg atcactcgta taaatcactg tttcttgatc agggatctcg ataaggtctt
     2341 cataaaaata cgggaaatta tttccatcct gtgtaaaacg aacttgagga taagataaca
     2401 attcttcttt ggtgatctct gcgtgttcag ctaatggatg tccttgcctt aaaaaaatat
     2461 gcgttttgaa ttttccaatg ctgcggccac ttagctctcc ttgttgtaaa tatcttctga
     2521 taccagcttg attatgctca ttcatataaa taatgccgat ctcactgtgc tgctctttga
     2581 cttcttcgat cactctcgct gttgtcgtct ccatgatccg aaattgtttg atctcgtctt
     2641 tgaattcctc gagtagctgt gcggtcaaag gacctaagaa atcataatgc tgggcagcga
     2701 tcgaaaaatt gtctctcttt tcactcgtta gatagtgagt ttctaatgta tcaagctgga
     2761 ccaatatttt ctcggcacga tttaagaagt cttgcccttc ttctgttaaa tatgcccctc
     2821 gattcgttcg agtaaacagc gtgatcccta actcggtttc taattctttg ataccagctg
     2881 aaagacttgg ctgggagaca aacattttct ttgccgcttc tctgaaacta ccattgtttg
     2941 ctacagcgac cacgtatttc atctgctgaa tattcattgc tcaaactcct cgaaataata
     3001 aatttctctt ccattcaagg gctggattgg tcggttgttc ggtcgagcat actgaccatc
     3061 gaaggggaga agaaactctt ggttcagttt tcctacatga tccattacaa accattggat
     3121 tggcccgctg gtaggcggag ttgtcaatga gccaatataa tggaaatggc ttttttgctc
     3181 cggaaagaac acatccggat ttacccaatg ctcatgtttt tctaagttcc aactttcccc
     3241 attttcttga ttatacagcc aaccttcctg taccattagc tggtacatga cacccacaac
     3301 tagattctct tttttgctgt tcatatgaac aaaatgaaat tcaatatctt cctgttttcc
     3361 gttgatgata tgttcagaag gcaagtggaa atgaatatct gtcaaataat agcgttcttt
     3421 cttgaactct acataactga gttggtcaaa aggtactaaa tgaatcgtgt ttttgaattc
     3481 cttgtcagta aaccgttgct tttgataatg aaaggaaagc gtgtctcctt ctattttggt
     3541 ttcttccccc ttggtcaaat gaataggcga ctgcaatgga aattccgcac ctctcgcaaa
     3601 ccaatcacat aaactcgccc aattttccgg acctttgtct ccagaatagc cccattcgac
     3661 atccatattc tttttcaact atacttcccc ctgcatctca tatcattttt atttttcttc
     3721 tttctttaca atcgttgaga cggtttctaa aaacgcctct tttccataaa attcctggtt
     3781 caatagttcc ggaaatatct ctttaaagaa atactgaaca gaaggccgat gttcaaagct
     3841 tttaatcgta gtcactgcct caatgaacat ctccttataa actttttccg ggttattttt
     3901 gatgatttca tcaaaagatt cataaagaag gtcaacctta tctgaaatgg ctaatagttc
     3961 tccttctacg gtttcatctt ttccttcgaa caaccgacgg cgataaactt cttggaactc
     4021 agctggaatc tcttggttga tgaattcgtc cgtcatcttt tcttcaactg tttgcagcat
     4081 ccctcttaac tctttgcttg cgtatttcac cggcgttttg atatcaccaa taaaacgctc
     4141 tgtgtagtca tgattcaatg atttttcata gagcagtttc caatcgatcg gttgtccatt
     4201 cgcttcttca atgtctccta gaacttgcgc aatagatgct acacgatacg aatgtgctgc
     4261 aactgtatgc tctgtatatt taaaaaatcc aggtgccctt gtgatcgtct ctaaattgtt
     4321 caatcctaaa ataaattcat tcaaccccat aaaagttacc tccctttgag atttcttttt
     4381 ccgaatatca tatcattaaa taactgatat tcgcaacatt tccgctcttt accatttttg
     4441 aaacagctcc cttaccaaaa aatagagaaa atctatatat aatagaaaaa agagaagaga
     4501 ttattctctt ctttctgcta accagtctta gaaaaatgaa ttttaaaaaa atcaaaaact
     4561 gatcacgata gaagtttctt ttcatacctg atgaaaagat gcttctcgca atcagttttt
     4621 ggatttttgc tattccaatt gatgattctg gagacacaaa tcggatttct ctatcttcat
     4681 caagcgcgct taaatctgcc aattttcagg atcttttttc cattctttta gcagagttaa
     4741 ttcttgctca tcgatataac gatcttctaa agctgcttca atcaatacag aataattggt
     4801 caacgtcata agagggattt cggctttttc gaaatttgct tttccttttg gcaactcata
     4861 cgtaaagata gccgcaacac caaggatatc cgcaccttct ctttttgctg cttcagctgc
     4921 ttccaagaca cttccgcctg tagaaatcaa atcctcgatc acaaccatct tctgaccttc
     4981 aaatatacgt ccttcgattt ggttaccttt cccatgatct ttcgccttac ttcgaatata
     5041 gaccattggc aaatccagta tttccgctac ccatgcggca tgagggattc ctgctgttgc
     5101 agttccagca atcacttgta cttcagggta agcttctttg attttgcttg ctaatccttt
     5161 tgcgatctct tttcggactt ttggatagct catcgtgatt cggttatcac agtaaattgg
     5221 gcttttgatt ccacttgccc atgtaaaagg attacttgga tttaaaaata ctgcttcaat
     5281 ttctaataag tcttttgcga tactttgttc aacattcatt ttaggttagc tccattctgt
     5341 ttgaatcgtt tgatatgctt tataaggatt agttgactga gtgattggtc gacctataac
     5401 gataaaagtt gagccgatct tttttgcctg agaaggtgtg actactcttg tctgatctcc
     5461 tgcgactgtt ccttctggtc ttatacccgg agttaagcaa acaaattcgt ctcctgccat
     5521 ttctttgatc gcttctactt cccaagcaga agaaaccaca ccatctaatc ctgctttttt
     5581 ggcacagcta gcataatgga tcacactttt ttctaaagaa acttcgatta gttgatcggc
     5641 atgcatttct tcttcacttg tagaagtaag ctgagtgata gctagaagta gcggacgttt
     5701 tccaccttct ggagtcccct cttctaatcc tcgcattgcc gcctccatca tacgaatacc
     5761 gccagcggca tgaacacagg tgagatcaac accaagcttt gccaatcccc gcattgcttt
     5821 ttcgaccgta ttcggaatat cgtgaagttt cagatctaaa aatacattat gaccagcctc
     5881 ttttagataa cgtacgattt caggtccttc ttggtagaac aattccattc cgattttcac
     5941 aaacaatttt tcttctttcg ggaaaaatcg aagaaagtct tctacctctt gcctagttga
     6001 aaaatctaat gcaataattg gtcgttggtc tagttgattc atcgttcacg ttcctctctc
     6061 acttctttga ttaatctttc cagcgattcg atgcctagtt cgctcattcg cacagggagc
     6121 tctttaatta gtttaggaca gatatacgga tcggtgaaat tcgcggtccc tatagctaca
     6181 gcacttgctc cagccataaa catctcaaga acatcatcca ctgtctgcac gccgcccatc
     6241 ccaatgattg gaaggctgga tatacttgct acttggtgaa tcaaacgaat agcgacaggc
     6301 ttgattgctg gtccggagag tccacctgtt tgattggcta aaatcggttt tcttgtctta
     6361 aggtcaatcc gcataccaag aagagtattg atcatcgtaa acccatctgc ccctccagct
     6421 tcgattgcct gagcgattgg aacgatgtct gttacatttg gggacaattt gacatagaca
     6481 ggaacagaag aaactttctt tactgcttgt gttaattgaa aagcaacatc agaatctgtt
     6541 ccaaaagcaa ttccgccatg tttgacattt gggcaagaaa tgttcagctc gattgctttc
     6601 acatttggtg cttcgccaat tttgctacaa acttctacat agtcttcttc acaagcacca
     6661 gcaacatttg cgatgatggg taactcattg tactcctcta attctggaag aagtttatgc
     6721 ataacaacgt ctagaccagg attttgcaaa ccaattgcat tcaacatgcc agatggtgtt
     6781 tccgccactc ttggcgtggg attgccaaag cgggcatttg gagtcgttgc cttgaccatg
     6841 atcgatccaa gctgattcaa atcatagtat tttccgtatt ctttgccaaa accgaaacag
     6901 ccgcttgccg gcatgatagg attttttaat tctaggccag gaagtttgac cgctaaagga
     6961 ttctcattca tataattacc tctcctattt taaaaatcgg tccttcgtca caaactttca
     7021 cactttttgt tcctgtttca tcttccggcg tatgacaaac gcaagcatag caagccccta
     7081 tcccacatgc catgcgggat tctaatgata actggacatt ttgatgcgaa gaaaacagct
     7141 gttccactgt cttcaataac ccgtttgaac cacatgcaaa aacagctgta ggttccgtct
     7201 tcgttcctaa caataaatta ccgacatttc cgtgcatacc gtatgttcca tcgtcagtag
     7261 cgattcttgt ttctcctaga cgattaaatt ctttttcata ataaacgact tcatgtgtgg
     7321 caaaacctaa aaaatgcgtt ggcttaattc ctttttcgac taactgtttt gataactcat
     7381 atagaggagg gacaccgatt cctccaccga ttataaatac ttcgtctcct gtatgaagat
     7441 tggacaaatc aaaaccattg cctaaaggac ccatgacatc taaatggtct ccggcagaaa
     7501 gagtagagaa gactctagtc ccctcacctt ccacccgata aatgatacgg caagtatttg
     7561 tttcgtggtc gatatgattc aagctaatcg gtcggcgtaa tagcaagtct gcacgcggca
     7621 cgagaatatg caagaactgt cctggttgct gcatttcttt tactagatca cctttcaatg
     7681 tcatttcaaa aatctttggt gccagctgtt tttgctgaac gatttccatc atttcttgtt
     7741 tcatctgtcc cctcctgcaa cggtttttcg tctttttgtc ttaacatgtg ctcgccgtta
     7801 aatagggtta gttgaaaaag cacgggattc catcactcga acgatcgcat ctgctgtgtc
     7861 taaagaagta aacaatggaa taccatgttc aactgcttct cttcggatga tgaaaccgtc
     7921 tttagaagca tttccccgat ctttatcaat cgtattgaca accacttgtg ttttaccatc
     7981 tcttattaag tcgactacat ttttttctgc tgcttcctca gaaattttcg ctactgtttc
     8041 aacgaccaga ccattttttt cgaaataagc agctgtatgt ttcgttccta tcagactata
     8101 gccaatttct gtaaaacgtt tagctaattc tagtgcttct tcttttgttt cgtccgcaat
     8161 cgtaaataat acggctccat attcaggcaa gtgtaatcca gaagcttcga atgccttgta
     8221 caaagctttg tctaattgtc tgtcagatcc cattacttct ccagtcgatt tcatttcagg
     8281 ccctaagtaa gtatcaactt tctgcaattt cgtaaaagaa aagacaggtg ctttaacatg
     8341 aacttctttt gtttctggat aaagtccgtt ttcataacca agtgtcttta gtttctctcc
     8401 caaaatagct ttcgtcgcaa tttgtgccat tggaattcct gtcaccttac ttaagaatgg
     8461 aacagtccga cttgctcgag gattgacttc gatcacataa acctcatttt catggatgac
     8521 aaactggata ttcatcatcc cgacacaatt caaacctaat gctaagcgga tcgtgtaatc
     8581 ttcgatcgtt ttcttgatcg attcagataa tgtttgaggt ggatacacag ccattgaatc
     8641 ccctgaatgg acaccagcac gctcaatatg ctccatgatc cctgggatga gtactgtttc
     8701 accgtcacaa atcgcatcca cttcgcattc accaccaagc aagtaacggt ccactagtac
     8761 tggatgttct ggagatgctt tcacagcatg ttccatgtaa tcttctaaat ctcgctggtt
     8821 ttcaacgatt tccatcgcac gtccgcctaa tacatagctt ggacgaacaa gaactggata
     8881 accaattctc gaagcgataa ccacggcttc ttctttactt gtagcagtat cccctaaagg
     8941 ttgaggaata tccaactctt tcagcgcttg ctcgaataaa tcacgatttt ccgcacgatc
     9001 caagtcttcg atcgttgtcc ctaagatttt tacaccagca gcagtcaaag gttcggctaa
     9061 gttgattgct gtctgaccac caaattgaac gattactcct atcggctgtt ctagctcgat
     9121 cacattcatc acatcttcga aggtcaatgg ctcaaaatat aatttatccg aaatagaaaa
     9181 gtcagtcgaa actgtttcag gattgctgtt catgatgatt gcttcgtatc ctgcctgctg
     9241 gattgctttg acagaatgca cagtcgcata gtcaaattca accccttgtc cgatacggat
     9301 aggaccagat cccagtacta gaattgaggg cttttctgat cgtgaacttt cattttcata
     9361 ttcataggaa ctataaaaat aaggtgtttt tgattcgaat tccgctgcac aagtgtcaac
     9421 catcttatat acaggaatca aatcattttc ttttctcatc tggcgaacgg cttcttcgtt
     9481 tatttcccac agctccgcca cttttttgtc tgtaaaaccg ttttgtttcg ctgttttcaa
     9541 tatcttgtca tccaacggct gctgtttcaa ctgctgttcg atttctacga tatgcaacag
     9601 tttatctaaa aagaataaat cgatttttgt caaatccgct aattcttcta tggtgtaccc
     9661 tcttctaata gcttcagcta cataaaacag gcgatcatct tgtgctcgaa ccactttttg
     9721 gattaggtca tcgtccgtga tgtctgccaa ctcaggaagt tcgatatggt gtgtaccgat
     9781 ttctaaagaa cgcacagctt tcaataaaga ctcttcgata ttccgaccga tagccatcac
     9841 ttcaccagtt gctttcatct gcgtgcctaa aagccgttct ccgttttcaa acttatcaaa
     9901 cggccagcga ggaattttag ctacaacata atctaatgca ggttcaaatt ctgcaaaagt
     9961 cgttcctgta acaggatttt tcatttcgtc taatgttaat ccaagcgcta ttttagcagc
    10021 tagcttagcg atcggatagc cagtcgcctt acttgctaac gcagatgaac gagaaacacg
    10081 cggattgact tcaatcacat aataattaaa actatgtgga tcaagagcga gttggacatt
    10141 acagcctccc tcgatcttaa gtgctcgaat aatcgaaaga gaagcatcac gaagcatttg
    10201 atattcatgg tcagacaatg tttgactagg ggcaaatacg atagaatcac ctgtatggat
    10261 acccaccggg tcaaaatttt ccatattgca gacaacgatt gcattatcag ccgaatctct
    10321 catcacttca tattcaattt ctttaaaacc tgcaatactt cgttcaatca aacattgggt
    10381 agcgggggaa agacttaatc cattttctga tacgatacgt aattcttctt cattttcaca
    10441 catacctcca ccagttccgc ctaaagtaaa ggctggacga acgatgacag gatagccgat
    10501 tttatttgca aaatctacag cttcttctac tgtattgacg atttcagact cggggattgg
    10561 ctgattcaat tctttcatca actgtttgaa tagatcacga tcttctgctt gatcgatcgc
    10621 agaaagcttt gttcctagaa gttctatgtt caattcttct aaaatacctg atgctgccag
    10681 ctccattgcc atattgaggc ctgtctgtcc gcctaaagtt ggaaggagag catctggacg
    10741 ctcttttcga agaatccttg atacaaattc aagtgtgatc ggttcgatat atacttgatc
    10801 tgccacttct ttatccgtca tgatcgtcgc aggattagaa tttactaaaa ccacttcata
    10861 tccttcttct tttaaggcaa ggcaggcttg tgttcctgcg tagtcaaatt ctgcggcttg
    10921 accaatgatg atcggaccag atccaatcac cataattttc ttgatatctg tacgtttcgg
    10981 catctgttta ctgctccttt cctgcgtcca tcatttccat aaattcatca aataaatgta
    11041 gtgcatcatg cggaccaggg gcagcatctg gatgaaactg cacactgaaa gcgggataat
    11101 ctctgtgttt gactccttct actgttccgt catttacttc tacatgagtt acgatgagtt
    11161 tttctggatc aatcgtggct tcatcgactg catagccatg attttgagaa gtaaaatcaa
    11221 ttcttccggt cgctacttct cgtaccgggt gatttaatcc tcgatgtccg aatttcattt
    11281 tataggtatc tgcaccgttg gctaaagcaa ataactggtg accgagacaa ataccaaaaa
    11341 tcggtacttt tccttggatt tttttgatca tttcgattgc ttctggcaca tcttttggat
    11401 caccaggtcc attcgtcagc atgactccgt ctggtgatag cgctaaaatc gtctcggcat
    11461 ctgtgttata gggaagtact gtgaggttac agtttctttt actcaattct cgtaaaatac
    11521 tatgtttcaa gccgaagtca atgacaatga ctttccgacc tgttcctgga cttggataag
    11581 gtttgttagt tgagacttgc tgcacttgat tggttgctag aacggttgct ttcagctgat
    11641 caaatgcatg ttcgaaggaa tctccagcat caactatact agctttcatc gttccgactt
    11701 cacggatttt gcgagtaagg gcgcgcgtat cgatacctga tattccagga attccttttt
    11761 gtttcaaaaa tgaatctagc gtcatttggt ttcgccagtt tgaagctaca cgtgcatgtt
    11821 cttttactac tactcctttg catgttggag aaatcgattc ataatcatct ctatttaccc
    11881 cataattacc caccatagga taggtaaatg taatgatttg accgttaaaa ctttgatcag
    11941 tgatagtttc ttgataacca gtcatacttg ttgtaaaaac gatttctccg aagacactag
    12001 catctgcacc aaaagccttt ccttcgaaaa ctgttccatc ttctaatata agcaaacgtt
    12061 ccatactttt attctccctt ctgccacaca agttttccgt tgacaaaagt catttgtgtt
    12121 tcgcctttta ctttccagcc gataaaaggt gtattctccc cttttgataa aaagtcttct
    12181 ttatcgatcg tgcaagtttg tgtaatatca aaaactgcta catcagcggg ggcaccaacc
    12241 gttagcgttc ctgcattcaa accaaaaatc tcagccggtt taactgccaa ccaattgatc
    12301 acttgttcca acgtgaatcg accagtttct acaaaatgag tatagatcag ttgaaacgct
    12361 gtttcgcttc ctacgatacc aaatggtgat ttcatgaaac tttggctttt ttcttctaat
    12421 ccatgggggg catggtctgt agcgatgcaa tcgatcgtac cgtcaagcaa gccttcgatc
    12481 aaagcttctc tgtcctcccg tcctcttagc ggcgggttca ttttccaaaa gccgaaatct
    12541 tcgggaatat cttcgtcgat caaaataaga tgatggggtg aaacttctgc tgttacgtgg
    12601 attcctgctt tttttgcgtc tctgattaca cggacacttt ctttagtaga aacatggcaa
    12661 acatggtaat gaacaccagt tgcttcagct agcaacagat ctctagcaat ttgagaagac
    12721 tcggttacgc ttaagatccc gggaagacca agttcttctg ccttcttgcc agcgtgcata
    12781 acgccgccaa ataataaaga ttcatcttct gtatgggcta ctagggcttt attgtttttt
    12841 gcagcttctt tcatagccag atacatcgtc ccagctgttt ggacacctac accgtcattt
    12901 gtgaaagcaa aagcaccttc ttcaatcagt gcttcttgat caactaattt ctcacttcgc
    12961 agattttctg tgattggcgc atactgcaat accttcacaa ctgcatcttt tctaatgatg
    13021 tcatatactt gtctcagctt ttctgccgta tcaggtacag gatttaaatt cggcatcgcg
    13081 catacagtag tgaaaccgcc acgagcagct gagcgagtcc cagcttcgat cgtctccttg
    13141 tatgtaaatc ctggctctct caaatgaaca tggacgtcca ctaaaccagg tgtgatcaat
    13201 tgtccctttg catcaaacac ttcatcaaat tcggcttctg agaatcctgt accgattgct
    13261 ttgattcgcc catcttctat ccaaatttct gctggtgtcg tcatattttt tcgtgtattg
    13321 atctgaccgt ttttaatgag tgttttcatt ttttcatcct cctataatta cgcttttcca
    13381 tttagcactg cttctaagat tgccattctg acgaatactc cattgctcat ttgctgaacg
    13441 atccgcgact gtaatccttc cactaatgaa tcagctaatt ctacatcacg gttaactggt
    13501 gctgggtgca taatgattgc atgtttttgc aacttcttcg cacgctcaac tgttaaccca
    13561 tgttcctgat ggtagccttc ttttgagaaa ctttcttttc catcatggcg ttcgtgttgc
    13621 acccgaagca tcatcatgac atcaacttga tctagtagtt catccaatgg catataatgt
    13681 ccgtacactt cgaattcatc gtcgtaccat tctctaggac ctgagaagaa tacttgtgcg
    13741 cctagacgtt ttaacatctg catattggat ttagctacgc gagagtgagt gatatcacct
    13801 acgatggcaa ctttcagacc ttcaaaatga ccaaattctt cataaatggt catcaaatca
    13861 agcaagcatt gggttggatg ctgtccgctt ccgtctcctc cattgataat cgaacactgg
    13921 attgttttac tttgtatcag ttcgtcataa tagttctcat caccatgacg gataaccgct
    13981 acgtctacgc ctaatgctga catcgtcagt actgtatcgt atagtgtttc ccctttttgg
    14041 acagagcttg tgcttgcttc aaattcaatc acttctagcc ctagtttttt ctccgctaca
    14101 tcgaagcttt tatgtgtgcg agtactattt tcgaaaaaga ggtttgtagc aaagtactgg
    14161 cgcttttgcg gagtccaatt agcaccttgc ttgaattcct gccctctgcg gatcaagccc
    14221 ataacttctt gatcagtaag tgcctcaacg gtcaataaat gctttaagct gatacgttct
    14281 gatttgatga tcataatgtt tcctccttag ttttcttcgc ttcgtgaagt ttctggtaag
    14341 ataagattta aaatgatgcc aagtacagtt gctaatgcca ttgccgacaa tgtaaatgtg
    14401 cctacttcaa agacgagtcc gccaattcct actactaaga taactgaagc aatcaacaga
    14461 tttttctttt tatcaaaatc gattttgttc tcgattaaaa tcttcattcc acttgcggca
    14521 attactccaa ataagataaa actgattcct gagatgactg gtccagggat acttaaaatc
    14581 aaagcgctta attttcctac gaatcctaaa atgactgcaa atactgcagc tccaccgatc
    14641 acaaacacgc tatggacacg tgtgatagcc agaacaccaa tgttttcacc gtaacttgtt
    14701 acaggaggac ctccgacaaa ggctgccacg atttgtgcta atccatcacc tgtcaacgtc
    14761 ttatgaagac ccggttcttc aaagaaatta cgtttagtta gtttattcaa taccataaga
    14821 tggccgatat gctctgtcat cgtcacaaaa gcgatgggtg ccattgttgt gattgctcca
    14881 agatatagct ttggttcata ttgtacaaag ggaatctcaa agttaggaac agcaaaccag
    14941 gcagcgtcta cgattggctt agtatccacg attccaaaca gcaaggctac gatgtatccg
    15001 ctaataatac ctagtaaaat cggaatcaat ccgagaaaac ctcttagcca catgttgaag
    15061 aaaattgtta atcctaatgt gatcagcgct acagcaatat acttgaaatc atacgtgccc
    15121 tgattataca tagcatttgt tgctgcattt gccgcaagtc ccaacccgat aaccatgatg
    15181 actggaccga cgacgattgg aggcaagatt ttatccagcc atgctgaacc gatctttttg
    15241 atgatcagcg caacaatcaa atagactaat ccagttgtga ctgctccttg tgcaatcgct
    15301 ggataaccat ctgttttcat caaaagctgc atcgctgcaa tgaaagcgaa gctgcttcct
    15361 aagtacgcag gtatctttcc tttagtagta aataagtaca ccaatgtacc tagtcctgaa
    15421 ctgactagcg caatacctgg atcgatacct actaagatgg ggactaacac ggttgctccg
    15481 aacatcgtga acaagtgttg taaacttaat cctacccaat gtcctggggt tgggcgatcg
    15541 tggatatcta acaccacgtc atcattatga aatccttttt tctccgacat gtttctctct
    15601 cctctaatct tcctctttca aaatcatgat gcgatcttgt ccatcaagct cttgcatctc
    15661 tactaaaatc tcttccgccc gagatgttgg aatgttcttc ccaacataat ctgcacggat
    15721 tggcaattct cgatgcccac gatcgaccag gactgctaat gaaatttttc ttggtctgcc
    15781 aaaatccatt actgcgtcca ttgctgctcg aatcgttcgt cctgtataca aaacatcatc
    15841 aatcaaaata acttcttttc cttctaagga aactgggatg tcagaagaat gaagttccgg
    15901 ttcttctgga ttttcttttt tgtcatctcg gtataaagtg atatccagtt ctcctacagg
    15961 aatatcgata tcttctagct gcttcaggcg ttcggcaatt cttgatgcaa tgtagattcc
    16021 tcgtgttttg atacctacca atacgatatc ttggatacta tggtttctct cgataatctc
    16081 ataagtaatt cgagtcaatg ctcgcttcat ggttacctga tctactactt cttttgcttg
    16141 cattttcatt ccccctactt ttttgcataa aaaaactcct gccctaagag gacaggagga
    16201 atgtttagac tgagcgtata ctgatacact gatagctata ctatgtcaat gagcaatcta
    16261 cttatggcgc accatacgta tccttgctcc cacccttctt agcctcacgg gactaaactt
    16321 aaaggaattc tattaagttt tatgctttcg ttgttaatta ctataccgtt atctaaatta
    16381 aaatgcaatg ttttttctta atttttctaa agttttttca aaaacttctg gaagaggtgc
    16441 ttcaaagatc atcttttcgt ttgtagtcgg gtgcgtaaaa cctaacattt gcgcatggag
    16501 aaactgacca ttgcctttca aagttttctt cggtccgtat actggatctc cagctaacgg
    16561 ataaccgata tacttcatat gcacacggat ctggtgtgtt cttccggttt ctagttttaa
    16621 ttcaaccaga gtaaatcctt cgaaacgttc caatacagta aaatgtgtga cagccgactt
    16681 cccatcttct cttatcgcct gcattttccg gttttccttc gaacggccga ttggcgcatt
    16741 gatggttcct ttttcgtgag gaatctctcc atggactaaa gcaacatatt tgcgcaaaga
    16801 ggtcttatct tttaattgct gagctaatga ttcgtgtgcc tggtcatttt tggcaaccat
    16861 tagcagtccg gaagtatctt tgtcgattcg gtgaacaata cctggacgaa taacgccgtt
    16921 gatcgtagaa agatccttga tatggtacat cagcgcattg accattgtgc catgcgtatg
    16981 acctgctgaa ggatgaacga ccattccttg aggtttgttt atcaccgcta catcttcatc
    17041 ttcgtaaacg atcgtcaacg ggatattttc tgggaccaca tctaatgttt ctggttcggg
    17101 gatcaagaca gtaatctcgt ctccttgttt tactttgtaa tttgctttga ctggctgtcc
    17161 attgacagaa accgctccat ttttcagcca cagctgaatt tgcgaacgac tgtaatcggt
    17221 gaataaatta gtcaatactt tatcgatcct accagattca tggtgaatcg tcgttttaag
    17281 ttctgtcatt tttttctttg atccttttca tctaaaataa tataaattaa catacaaatc
    17341 actccacata caagtgtcac atctgctacg ttaaaaatcg gaaagctcat aaaatctgtc
    17401 tggaacatat ctactacata gccaagacga atacggtcga taaaattgcc aatcgcacca
    17461 gctagaatca aactcaatcc aatcatgaac cagcgattac ctttttcacg atttttaatc
    17521 atcaatgtga gaatcacaac gactgcaatg agtgtcacta tagtaaagaa ccacatcttc
    17581 ccttctagca tactccatgc ggctccagtg tttcgaatat gattcagtga caaaatacct
    17641 ggtataagat ttttcgtctc tccaagcgct agattatcag tgatccacca tttgaccaac
    17701 tgatccactc ctactagcaa agcgctgaat atccaataaa taattaacaa aaaatcaatc
    17761 cttttctatt tgtttataaa tatcacgagg tcgtacgatc ccgagcagat taccatcggg
    17821 attcccatct ttagtgataa gtacggcttc caaagtccct tgctcacgaa acatcgcttc
    17881 aacctcgtaa atatgtgttt tagctggaac aaaatgataa tttgtgtact ttccgttttg
    17941 gatgatcaaa tccaacgctc gtttatttgt taaatcaacc ggaccttttt ggctttcttt
    18001 tgctagccaa aacccgatat tacgtaaagt aatcaatgct acaaattttc ctttattgta
    18061 taacggaaat tgtgaatacc ttttttctgc tactatcttt aacagttcaa gtaacggaag
    18121 atcttgttca aaacctgtta cacgttttgc aaatcgaggc agcacggttt caggctgaat
    18181 cagttcttgt tcgatcagct ggattcgctt gactgtccaa tcatttggct ctgcaatgac
    18241 aaaatcgact gcgatccgat catggacgat cgcattcctt aactgagcaa gctgtaaaag
    18301 atcatcttcg tattttctga tcattaattg ttttctttga gctaggcgtc tgacaagttc
    18361 ggtaaatccc atatttcgtg catttcccat ctcgtctctc atccattttt cgattcgatt
    18421 gaaactgatt aaaaaaagat cagagtttgc cataattttc ctccttgatc aaatatgccc
    18481 ggttttttat atagaaaaag aacgcaatca acacaataac tgcaaaaaaa ctgaaaaata
    18541 aattttgtag gaaaacggcc cccaacccag ttgctagaaa taaaaacgga tagatttgaa
    18601 gaatcaagta attcattgtg atcacataag caggctttgc ttctttcact gtataaacgg
    18661 ggctttttag ccaataaaag gtgacctgca tcgtaaaggg cacttccaga tcaagcgtta
    18721 tcttttgttc atgactgaga acactgcgtt tttcattgtt gattcttagc tgaatcgagc
    18781 tacccatacc gtaaaaaccg gtttttctta taaatgtcgt tttcatcata ccctcctatt
    18841 atgctttagt atagctcaaa atacaataaa gaaaaagaat gatcctagtg taaacaaaat
    18901 taattcccta tcgtctaaaa aaagaagctg tagtcaaaat acagctcctt cgatggtaga
    18961 ttataatcaa gcttaaaaca atcccaacac ttctccgtca tttgtcacgt ccatattcaa
    19021 tgcagcaggt tttttaggca aaccaggcat cgtcataaca tctccagtca aggctactaa
    19081 aaatcctgcc cctaattttg ggatgatttc gcggatcgtg atggtgaaat cttccggtgc
    19141 acctagcagt gaaggatcat cagaaaatga atactgtgtt tttgccatac aaatcggcag
    19201 tttgtcccat ccattcttcg taaactcttc tatttgtttt tgcgcttttt tgctgaaaac
    19261 aacaccattt cctccgtaaa ttttcttgac gattgtttct gtcttttctt gtatcgtttc
    19321 ttctaggcgg tataatggct tgtaattagc ttcttttcta tcaatcaatc gtactacagc
    19381 ttttgctaaa tcaacgccgc cttctgctcc atctgcccat acactcgctc tcttggcaag
    19441 aatcccctga ttttcacaca agtgctccaa cagtgtgagt tcattgtctg tatctgttac
    19501 gaattcattg attgcgacga tcacaggtag ctgatattgt tccatattac gtatatggcg
    19561 ctttaaattt gcaaaaccta ctttcaaagc atcaagattc tcatttttaa gttcatcttt
    19621 tttcattccg ccatgcattt tcaatgcacg gacagtggcg acaatcacca cagcatccgg
    19681 cgcttttttc aagttaggta ctttgatatc taaaaatttc tctccgccaa gatctgcacc
    19741 aaatcctgcc tctgtgacaa cgtaatctgc taatctcaat gctgtcttgg tagctaaaat
    19801 actattgcag ccatgagcga tattggcaaa cggtcccccg tggacaaaag ctggtgttcc
    19861 gtaaattgtt tgtacaagat tcggcttgat tgcatctttc agcagtaatg ccagagcgcc
    19921 ttctgctttc aagtctccag cagtcacagg ctgacggtca aatgtatagc cgacaacgat
    19981 ccttgcaaga cgagccttta aatcttcaag gtctgccgca agacacaaga tagccatgat
    20041 ttcgctggca actgtgatat caaacccatc ttctcttgga acaccttgga ttggcccacc
    20101 caagccaaca attactttac gcagttcacg atcattgaga tcgactaccc gtttccaaat
    20161 cactcggcgg gcatcgatgt tcaattcatt tccttgatga atatgattat ctaaaagagc
    20221 agataatgca ttattagctg ttgtgatagc atgcatgtca ccagtaaaat gcaagttgat
    20281 atcttccata ggcaatacct gtgcatatcc tccgcctgca gcaccacctt tgattcccat
    20341 cacaggacca agtgagggtt ctcgcaatgc aataacagat tttttattga ttttattgag
    20401 cgcgtctcct aaccctacag tgatcgttga ctttccttcg ccagctggtg ttggattgat
    20461 ggaagtaact aagatcaaat gcccctcagc gttatccttt gatcgattga ttccagaaaa
    20521 attgattttc gccttatatt tcccatacag ttccaaatcg tcttccttaa gatctaattt
    20581 actagccact tcaacaatcg gttctagctc tgtttcttgt gaaatttgca gatcattctt
    20641 catttgatta ccccttttca cgaactttat tcaacaaaat atcttctttg ttaagatatg
    20701 ccaattatac ctttttttat tcagaaaaaa aacataaaat tacaggtttt taatttattt
    20761 gacgtactta taaatactct ttataatgaa ggctatgatc agactttaga aaggtcgtga
    20821 gtgctttgac cacaggaatt gtaaaatggt ttgacaacaa aaaaggatac ggctttatca
    20881 gttatgatga cacagaagaa atttttgtac attttactgc gattgaagaa gagggattca
    20941 aaactttgga agaaaatcaa gtggtcgaat ttgagatcat cgaagggaat cgaggaacac
    21001 aagctgccca tgtcaagaaa ggcaacgttc agactaccga tactagtatg catgaataga
    21061 taaacaaata gagtgagacg ctaaacggga tgaaccgtac gtctcactct tttcttttcc
    21121 tgtaaaaatt cgttttttta ggttctgatt tttaaaatta gctttttctt tttttcgtat
    21181 aaggataagg aattgattct gatttgggtc cgtttttttc aaaatgatca aaaaggacta
    21241 cttgatcttt ttttcgcatc atgaaaacag atggggcttt ctcatcttgc aacatcattt
    21301 gcaccccagt attagttggc gtcaaagatc gaatctgtcc gacagatatt tctcggtctt
    21361 tccaaaaagc agcataacgt ataatcacag agtttgattt taaaataaaa gaacgccgca
    21421 aacctagaaa tagaaaaaca agaaaaatac ctaaaacaaa attgcttttc caataaggac
    21481 ctgtgttttc taaagaaaga atcagactaa aaaacagaat gatcaaggtc aatgaccaat
    21541 agatgatcgt atgtgccagt tcaggctgcc atcgaatatt ttttttcatt ctctaacctc
    21601 tcaccgattc agtaatgata taatcttacc ataacattag tttgaacaaa aaggagaatc
    21661 tctttttatg ttaaaagtat acattgatgc ctctacaaaa ggcaaccctg gtcctagtgg
    21721 aggtggaatc ttgattgtct atcaaggtaa acaagaacag ctatctatcc cgctttctat
    21781 agggacaaac catcaagcag agttcgaagt ctttttaaaa actttagaat ttctaaagaa
    21841 aaacgactta cagaatgaaa cgattttctg tttttcagac agcaaaacac tagtttctac
    21901 ggtcgacaaa aacgcaacga agaacgagct cttccttccc taccttcaaa gaatccaaga
    21961 acttctatcc gaattttctt tattgatcct gcaatggttg cccgaaaaca aaaataaagg
    22021 agcagataat cttgcacgtc aggctctcca taaacaatta aaagaaaaaa agactcttta
    22081 aattaaaaac tttaaggagt ctttttatag tttctcattt aatataaaag ataattgtga
    22141 tcaaacgtaa tttccaattg gtaatctccg attttttctt ctatttgact acgtaagatt
    22201 ctttctagtt ctgtatcaac aaactggaat ttctcaggga ccactacatc aaattgcagc
    22261 gtttttcctt gatgaattac tctaaaatca tgaatattaa gccctgtacc tgtttcaaga
    22321 agaatttgct ttaactgccg caagatatta tagtattttt cgttatcaac aggcattgga
    22381 tccaagtgac agacaagttc cacatccaaa gactttttaa agtctttttc tatcagatca
    22441 ataatcttat gagccacatt caaattcatt gattcatcta cttcgatgtg gactgatgca
    22501 aagcgtttat tgggtccata gttatgcacc aataaatcat gatagccaag tatatcatcg
    22561 caagcattta aatgctcttc catttcttca atctctgctg gcgttgggcg acttcctaat
    22621 agttcgtata caaaatttcg aagcatcgtc aatccactat aaaggatata taatgctaaa
    22681 gcaaaaccta tatatccatc aatacgccat ccagttaccc attcgattgc tgctgaaagc
    22741 aatacagcca gtgtagtaaa gacatcatta taactatctg ttgctgtagc tctcaatgtt
    22801 tcagaatcaa tggattgcgc aataacctga tacattttgc cttgtgcaaa tttcaaaaag
    22861 atggaaatga ttaggacaaa aaagacgatg ggtgttaaag agacattttc tggatggatg
    22921 attttttcag cagaagactc taaaaattga aatcctacat aagtaatgat gatcgaaaca
    22981 aataacccac tgatatattc gaagcgttcg tgtccataag gatgttcctg atctgctggc
    23041 tttgcagcaa ttttaaatcc gatcaaagtc aatatggatg aagcagtatc tgatagactg
    23101 ttcactgcat cagccataat ggagacactt cctgaaaaaa gcccgatcat tagcttagag
    23161 acaaacaaga tcagattcgt aaccaatcct aagatacccg ctagtactcc tttttttgtc
    23221 cgctgttgcg gtatttgttt ctttttttct tcttgtttct tagccaagtt ttttacccct
    23281 tctagtttgc ttgttgctca ggtaaaaaga tggagaggac gattgttttc ctctcctctc
    23341 ttcctttttc tatctatcgt gcgtcctatt actattaaaa gatggtcatt attctggttt
    23401 caacggtgtt gctgcaaata acgcttttgc tagtaatggt gttatgattc ccgcacctat
    23461 tgcttctggt atcccattga ttgctgcaac ccctgctaag gttttaaata aaagagcaga
    23521 gtctacacca taggcatctg ccgttgcacc tgtataaaat aatcccatga atcctaacac
    23581 taagactgta ttgaccaatg aacccagtac ccctgcaaag gctgagctga tcgttattga
    23641 tttatttttt tgataaatcc agtggaaaac caagcctgct actaagccaa caagtactct
    23701 gggaactacc gagataatcg gattcgtgaa cactaatgta tcaaatggcg ttgttggcat
    23761 ggcataggca cgaacaattg tagcgattcc ccaaaacaag ccaatcacca tgccatcttt
    23821 tgggcctaat actactgcag caataattac tgtgatatgg ataattgtta aactaatgaa
    23881 tcctaatgga ataaacccca gccaaggaac catcgcttgt acgatgatga ttgctaacaa
    23941 gatcgcacgt aagactagtc gaaaggtctt atttctacta ttcatttttt cacccctttt
    24001 tatttatact aatcgtaaaa atttctgtca ctttcgtcaa ctaaagacca tccgaatccg
    24061 accatttgat tagatgcgcc atccaattga aaaaagtatg agggcaagac ttgtttgtct
    24121 tcgcccccat aatcatgttt cgttcaatgt ttgaactttt gtttttctgt caaacgtaaa
    24181 cgccctattg ttgcgcaacc cattctttcg cagctttaag tgcatctgga ataccagcag
    24241 gatttttccc gccagcttgt gccatgtctg gacgtccacc accgccaccg cctactttcg
    24301 gtgcgattgc tttaatcaag tcgccagctt ttagtccagc ttcatttgat tctttcgtca
    24361 ttgccgctag cagactgact tttccttctt gttcgtttgc taaaacaaga atatctgaaa
    24421 tatttttttg tttccattgg tcagctaatt gacgcagctg attcatatct ttcactttta
    24481 cttgtgctgc aatgattgtt tttccattga tcgtttctgg atctttgaat acatcaccag
    24541 cttgttgatt cgctaacttg ctagctaatt gttcattttc cttttgtagc tctcttactt
    24601 gctgttgcaa ttgttccgct tttgaaacaa cttctttcaa ttgaggtgat ttaacaattg
    24661 ttgctacttg ttttagttgt ttttcttctt cttcaagtag ttcgtacgct tctttacttg
    24721 ttacagcctc gattcgtcgc acgcctgcac caattcctga ttcagaaacg attttgaaga
    24781 ttccgatgtt ttctgtattt gctacatgtg tgcctccgca cagttcgatt gaccagccgc
    24841 caatatttac tactcgaacg tcatgtccgt atttttcacc aaacaaagcc attgcaccca
    24901 tgtttttggc tgtatcgata tctgtttcaa ttgtttcaac tgggatagct tcccagattt
    24961 tttcgttgac gattctttcc atttcagcta attcatctga agtgatttga ccaaagtggg
    25021 taaagtcgaa tcgtaaatgt ccaggagcga ctaaagaacc agcttgattt gcatgctcgc
    25081 caagtacttc tttcaatgcc ttgtgcagta gatgggttgc tgtatggttt ttgatgatcc
    25141 gattgcgcat cgattgatcg atcaatagat gataggtttg tccttcactc attggtgctt
    25201 ttacttctac ggtgtgcata aattgaccat taggcgcttt ttgaacatct gtaacaactg
    25261 ctacgatttc gcctacttca ttcatgatcc atccttgatc cgctacttgc ccacccattt
    25321 ctgcatagaa aggtgtttga tcaaagatca tttgagcttc accttctgcg acttcattca
    25381 aaagagactc acctttaacg atgaccaata attgactatc tgattcttgt tctgtgtatc
    25441 caatgaattt actttctact ttgatatctg tcaataaagc agattgtacc cccattgatt
    25501 tttcagtact gcgggcagag cgagcacgtt cgcgttgtgc atccatttct ttttcaaaac
    25561 cagcatgatc aactttcagt ccttcatctt ctgccacctc ttccgttaat tctaccggga
    25621 agccatatgt gtcgtatagt ttgaagatgt cttttcctgc tagagtcgtc ccgttttcgt
    25681 tttttacttc ttggatcact tgatttaaga tttccaaacc ttcattgatt gtttcattga
    25741 aacgttcttc ttctgtacgg ataacttttt caataaattc tttttgttga agtacttcag
    25801 gataataact taccatgatt tccccaacaa cagggactaa acgatataag aatgcttgtt
    25861 caatacctaa ttttttccca tgcatgacag cacgacgaag caaacggcgt aagacatacc
    25921 ctctcccttc attcgatggc aatgcaccgt cgccaatagc aaatgaaagg gcgcgaatat
    25981 gatctgcgat tactttgtaa gaaatatctg ttactgggtt ttcaccatat tttacttgtt
    26041 tgcttagctt ttctacggcg tggataatag gcataaacaa gtctgtctca aagttcgttg
    26101 acgcatcttg aacgattgag accatgcgtt ccaatcccat ccccgtatca atgtttttat
    26161 gaggaagtgg ttcaaatgtg ttatcaggct tatggttgaa ttctgaaaat actaagttcc
    26221 agatttctaa ataacgttca ttttctcctc ctggatagtt ttcaggatcg tcttctgcta
    26281 aatcgttata agcttctcca cggtcataga aaatttccgt atccggacca catgggcctg
    26341 caccgatatc ccagaagttg tcttctacat caataatgtg atctagtggc aggccaactt
    26401 cttcatgcca gatgcgtttt gcttctgtat cttttggata aactgttaca taaagttttt
    26461 ctggatcgaa tgccatccat tttggatcag tcaaaaattc ccatgcccag tggatggctt
    26521 catttttgaa atagtcacca atcgaaaaat tacccagcat ctcaaacatc gtatggtgcc
    26581 gtgctgtttt accgacattt tcgatatcat ttgttcgaat agatttttgg gcatttgtga
    26641 ttcttggatt ttctggcaca actgaaccat caaaatattt tttcaatgtt gcaacaccag
    26701 agttgatcca caataaggtt ggatcgttca cggggatcaa agacgcacta ggttcaatcg
    26761 tatgtccttt agattggaag aaatcaagaa acatttgtcg aacttgtgca ctacttaatt
    26821 gtttcatgtc attacctgct ttctataaat taaatacaaa aaaacaccat cacagccaag
    26881 gacgaaaact cgcggtacca ccttgattgc aatgatgtgt aatcattacc tcttaaactc
    26941 gataacgctg agctgcgtcg gtatttctac caaaatagaa aaagggagca atttgattag
    27001 tgactattct tttttcagcc aagaaagaat tttctgtgag tcttaaaaaa caaatcatat
    27061 ccttttcgta cttaattagt atacgcattc tattgatcac tgtcaatatc tcaattttta
    27121 ttttcatttc cttttggtca tactccacga tttttggtac gataagaata aaggaatcaa
    27181 tacatctctg ctattcatga caaggaggaa tatgatgaaa aaaatagttg gagcggatga
    27241 atggatacgc gcagctagct gctttttgag atatcaattt ttgtattaga acaagggatt
    27301 cctgcagaac tagaattcga cggaaaagat atcccgcaac aaacctatta tctatttctt
    27361 gatcaaaaaa gaccagtagc tactttgcgt tatgaaaaga aaacacctac ttgcttcaag
    27421 ccggaacgat tttgcgtagc aaaagaatac cgaggaaaag ggttaggcgg tcagttgctt
    27481 gaagctgctg aaaaacgggc ggtttcagaa ggttgtcaga ctagttatgt agtagctgaa
    27541 atgacggctg tagattttta tgaaaaacaa gggtatcata cttgcacaga accttttatt
    27601 gaagatgaag tactttgtat cggaatgaaa aaaagtctag cttaaaaaca agagattgtg
    27661 acacgccttt tgtcacaacc tcttgttt
//
LOCUS       DAFELK010000037        26200 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFELK010000037
VERSION     DAFELK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.038"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(12..2183)
                     /gene="copB"
                     /locus_tag="LP433_001850"
     CDS             complement(12..2183)
                     /gene="copB"
                     /locus_tag="LP433_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBL2005999.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2203..4389)
                     /locus_tag="LP433_001851"
     CDS             complement(2203..4389)
                     /locus_tag="LP433_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBL2006000.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4389..4598)
                     /gene="copZ"
                     /locus_tag="LP433_001852"
     CDS             complement(4389..4598)
                     /gene="copZ"
                     /locus_tag="LP433_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBL2006001.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4611..5051)
                     /locus_tag="LP433_001853"
     CDS             complement(4611..5051)
                     /locus_tag="LP433_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBL2006002.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5125..5664)
                     /locus_tag="LP433_001854"
     CDS             complement(5125..5664)
                     /locus_tag="LP433_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HBL2006003.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6279..7745)
                     /locus_tag="LP433_001855"
     CDS             complement(6279..7745)
                     /locus_tag="LP433_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2006004.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(8056..10137)
                     /gene="cadA"
                     /locus_tag="LP433_001856"
     CDS             complement(8056..10137)
                     /gene="cadA"
                     /locus_tag="LP433_001856"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL2006005.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(10661..11020)
                     /locus_tag="LP433_001857"
     CDS             complement(10661..11020)
                     /locus_tag="LP433_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBL2006006.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(11050..11391)
                     /locus_tag="LP433_001858"
     CDS             complement(11050..11391)
                     /locus_tag="LP433_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006007.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(11388..12062)
                     /locus_tag="LP433_001859"
     CDS             complement(11388..12062)
                     /locus_tag="LP433_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL2006008.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(13239..14537)
                     /gene="asnS"
                     /locus_tag="LP433_001860"
     CDS             complement(13239..14537)
                     /gene="asnS"
                     /locus_tag="LP433_001860"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBL2006009.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(14577..15767)
                     /locus_tag="LP433_001861"
     CDS             complement(14577..15767)
                     /locus_tag="LP433_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2006010.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFLKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(15788..16315)
                     /locus_tag="LP433_001862"
     CDS             complement(15788..16315)
                     /locus_tag="LP433_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBL2006011.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(16362..19151)
                     /locus_tag="LP433_001863"
     CDS             complement(16362..19151)
                     /locus_tag="LP433_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL2006012.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFIYVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGTGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMTTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(19298..19498)
                     /locus_tag="LP433_001864"
     CDS             complement(19298..19498)
                     /locus_tag="LP433_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2006013.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(19950..20270)
                     /locus_tag="LP433_001865"
     CDS             complement(19950..20270)
                     /locus_tag="LP433_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006014.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(20654..21772)
                     /locus_tag="LP433_001866"
     CDS             complement(20654..21772)
                     /locus_tag="LP433_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006015.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            22243..23550
                     /locus_tag="LP433_001867"
     CDS             22243..23550
                     /locus_tag="LP433_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBL2006016.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            23669..24868
                     /locus_tag="LP433_001868"
     CDS             23669..24868
                     /locus_tag="LP433_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL2006017.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYAWQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(24895..26163)
                     /locus_tag="LP433_001869"
     CDS             complement(24895..26163)
                     /locus_tag="LP433_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBL2006018.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT         7387 a         5652 c         4595 g         8566 t
ORIGIN      
        1 ttttttcatt attatttgat tttcaatgtc aaagcattta gagctacaac taccgtactt
       61 aacgacatca agacagcacc aactgctgga cttaatatga taccaattgg cgcaagaatt
      121 ccggctgcta gcggaattgc aagaatattg taacctgccc cccaccagag gttctggatc
      181 attttctttc gcgtttgctt ggctagatca agaaaatgca aaatatcttt tggatcgctg
      241 tttgtcaata cgacatccgc agaatcgatt gcgatatctg tccctgcacc gattgccatc
      301 ccgattgaag cacgggctaa acttggcgca tcattgatcc catcacccac catgattact
      361 tttttccctt ggtcaaggta tttctggaca acagcttctt tatcatctgg taataaaccg
      421 ccataatatt cttcgatccc taaataatct gctactgctt gggcagcgtt tttattgtca
      481 ccagtaagca tgacaggagt gatttttctt tctttcaatg ttcggataaa ttcttttgct
      541 tctgttttta ctacgtcacc taaagcaacg attgcagcta gatgattttc taaaatcagg
      601 aagctgatgg tatttccttg ttcttggtaa ggtttcaata atgcttgttc tacgtttaat
      661 ccgagacgct caacttcttt ttcattaact attttcactt gttgtttttt gactgttgcc
      721 tctagcccga ctcctgaaag attttttaga ttttcagctt gataaggctt gatttcatgt
      781 tctttcaaat aattcataat gccaacagcc aatggatgat tggcattcgc ttccaaggct
      841 cctagatatt gaaggatttc atttttattg aacgcatcat caagtacttc gacacccgtt
      901 acagtaaatt ttccttctgt tagtgttcct gttttgtcca gcatgatcac atctagatca
      961 ttggcttgct ccagtgcatt gcggtttttc aaaagtaatc cgtttttagc tgctattgat
     1021 gtggagcgag caacaactaa tgggatagct aaacctagag catgaggaca ggcgatgata
     1081 aagactgtta ccatacgttc taatgcatta ggaagatctg tcaagaacaa ccaggcgatg
     1141 aatgccagga tacccacaat taatgcgaca taaaacagcc attttgccac tttgtcagat
     1201 aatgactcta gcttggattt ttctccttgt gcttttcgca ccatttccat aaccttcgct
     1261 agataaccat tttcaccagt tccagttact tcgatttcga tcgttccatc cccattgata
     1321 gaaccgccaa tcactttgtc attggcttgt tttttgattc ctcttgattc gccagtcaca
     1381 gctgattcgt caacaattgt ttcacctttc aagattacac catctgttgg cattttatca
     1441 ccagaccgga cgatcaaacg atcaccttcg tttacttctt tcaatgaaac tgtctcttct
     1501 tttccatctt tcgtcaagcg tttcactgat tctggcagta attctgctag tttttgtaaa
     1561 gcattgctgg cattcgacac agcattcatt tcaatccagt gacctagtag cataataacg
     1621 atcaaagtag ccaattccca gaagaaatcc atgacgtgtg tatgtggatt gagcagattt
     1681 gcgataaacg aatagacact ataaatatat gcaactgtaa tccccatcgc gatcagtgtc
     1741 atcatagcag gacttttttg tttcaattcc atcttagctc cacttaaaaa tggctgaccg
     1801 ccatagataa atagtatagt tgctaagatc aatacgagcc aatcagaacc aggaaacgtt
     1861 acttgaaatg gaaattccat tcccatcatt ggtgaaaaaa gaatgattgg gatagctagg
     1921 ataagcgata gccaaaattt ttgtttgaaa ttccccatgt gcatggaatg atccatgccg
     1981 ccgtgttcgt gatccatgtg catcgaatgg tccatttgtt tgctgtttgc tatatctcca
     2041 tggttatgtc ccatgtgcat ggaatgatcc atctgactat ggtcatgttt catctccatc
     2101 tgtttttcat gagattctgt actttctttg tttactactt cttttttatg ctcatgtttt
     2161 ttctccatat cgttcccatt catttttact ccatcccttc tcttactttt tcatgtgtcg
     2221 atttaagctc agggagttca acaatacact gacggaacta aacgccatcg ctcctcctgc
     2281 aatgattgga ttcaaaaagc ctagtgcggc aaaaggaata ccaatcgtat tatagacaaa
     2341 agcccagaaa agattttgtt tgatttttct caatgtcaac ctagacaact cgattgtttg
     2401 tgcaatggat gccaaactgc tattcatcag cgtcacatcg gctgtttcca tcgcaatgtc
     2461 cgttccactt cccattgcca taccgacatc agctaatgct aaggccggtg catcattgat
     2521 tccatcgcct gccataccga cttttttgcc atctttctga agtttttcta cgtaggctgc
     2581 tttatcctct ggaagtactt cagcaaagat atgctttgga tcaataccaa cttgtttacc
     2641 aatcgtttcg gctgccagtt tgttgtctcc tgtcagcata aaaacatcta atcctttatt
     2701 ctggagctgc ttgattgctt gtttggcttc tagtttgatt tgatcagcca cggcaatcca
     2761 cccgatcact tgcttttcat cagctaaaaa catgactgtt tttccctgct gttctaattc
     2821 taacgcgtgt tcttggtatt catcaaatga taggttcaat tcaattaatc gtttacgtgt
     2881 acccgcaaaa tagcgtactc cattaatcgt accgctgatc ccagcacctg ggtgggctgt
     2941 aaaatcaatc atatcgtatg ttgctgcttc ttgcagtttt ccgtattcca cgattgcttt
     3001 acctagtgga tgttcagaag cttgttctaa agtataaaaa atagatagga cttcttttga
     3061 accgactaga tctgtaactt tgggctttcc ttctgtaatc gttccagttt tatccaaaac
     3121 aatgctgtct aagtgagcag ctgcttctaa tgcttctccg cctttaatta aaattccatt
     3181 tcgtgcacca acacccgttc ctaccataat agctgttggg gtcgctaaac ctaatgcaca
     3241 tggacacgca atgactaata cagagacact atggatcaat gcgagttgcc aatcaccagt
     3301 gatcaaacct gtagctatga gcgtgataaa cgcgatgact aatacgatcg gaacaaaaat
     3361 ccctgagatc cgatctgcga ttttttggat tggggctttg ctcccttgag catcttccac
     3421 catttgaatg atttgcgcta atactgtctg cttgccgact tgtgtgactt ccatgtgtag
     3481 cagaccattc gtattgattg tcccgccaaa aagcgtgtca tccggattct tttctacagg
     3541 aagattttca ccagtaagca tactttcatc tatcgcactg cttcctgaaa taattcgacc
     3601 atctgctgga atctgctcac caggacggat gactagttga tcaccaacga ctacttcttc
     3661 aatcgctaac gtttcttctt tcccgtttct tatcacttgg gcggtttttg tttgaagaga
     3721 catcaattgt ttgattgcat tacctgtttt cgtttttgct gtatgttcca aatatttgcc
     3781 gagcaaaatc agcgtgatga tcatactgct gctttcaaaa taaagatctt gggggtgtcc
     3841 acggaaaaat ccgttgtaaa tgctcaatgc aaaggcagcc gatgttccaa ttgctaccaa
     3901 tacatccata tttggtgctt tcgtcttgat tgcatggtac gcacctttat aaaaacgagc
     3961 accgacataa aattggacag gagcagacag cactaactgg acgattggaa aatgaaaaaa
     4021 gtgaacaatc gccgcatggc ttcctaacat catagcaatc attgacaaca tcaacggcaa
     4081 agtcaaaacc gtactcaata taagatcgaa tagcattttt ttcaaatacg cttgcttttc
     4141 ttctgcaatt ttttgtttgt gggcttcatc gtacaaaatt gcaccataac cgatgttttc
     4201 tacgctttgg attaattttt cagtggtcgt cccttcatat ttgacacttg ctttttcagt
     4261 ggccaagttg actgtggcat tgaccacacc aggttgtccg ttcagctctt tttcgatcct
     4321 agcagaacaa tttgcacaag tcatacctgt aatgacgaac gtatccattt tggtttctgc
     4381 tgttgccatc aaatcacctc tgctttataa cccaatccat tgattgcttg acaaatcttt
     4441 tcggattgaa cttttgtttc atcaaacttg accgtaccgt ttgctttttt caaatttact
     4501 ttcacttttt gcacgccgtc aagtgcgctt actgtttctt ctactcttgc tgcacaatga
     4561 ttgcagctca taccttcgat tgaaaattgt tgtttcattt tttcttcctc ctattgatgt
     4621 tgtttacatt cacattgacc tgggatacag ttacattcga tcgtatctac tggttgcttt
     4681 tgttccagtt gtttcaaaat ctcattgata tcttcttgag tcaaagtggc ttcttctact
     4741 agatccgcaa tcgtctctcc aatccttttt gcacagatat gggaaaaaag attttccgtc
     4801 gcactgcgaa ctgtttccat ctccgagaca gctggatgat aaatgaattt ttttccttct
     4861 tgttctgtcc agatcacttc tttttttacc aaacgtccca gcaaagtttt gatcgttgct
     4921 ggtttccaat ccatcgaatc agctaagatc tgcgtgattt cttgggctgt cgtctgtcca
     4981 agtgtccaaa taacacgcat gatctcccac tctgaatcac tgatctttac tggcgttttg
     5041 actttttcca tttatttcac acctttcgtt tacaaatgta atcattagct tatgaataca
     5101 gattacgctt gtaaacaaaa actgtcaatt atttttgctc tctattttca atttagttaa
     5161 aaattcttgt ttctctcgtc ttgttttaag gatgatcagt ttatttcttg cattagctac
     5221 ttggatcagc tgctgtattt tcggttcatt gttttcttca aaatgccaga taaaagataa
     5281 aaattctaag tattccctgt ttagtttctc tgaaaatgat tcaggcatat ctggccgaga
     5341 ttttttgttt atctttcttt ttagagaacg ccaaactact cggtagatgg cgagataacg
     5401 cggcacttta agccaaatga tcttatctgc ttctttaatc ctttcctcta atgtagaagt
     5461 ataatttcct tcaacaatcc atgacggatt agataccata aacgattgct gttcttgcaa
     5521 aaaccacttt tttgcctgaa tactgtagtc tgttgtatgc cataaaaggt ctagcggcag
     5581 tagcggaaag tcggtgattt ctttgatctt ccttgcgagg gtcgattttc ccgacccact
     5641 ttgtccaatc acgatgatct tcattcttct ccctcacttc tctttggaat ttggttcgat
     5701 cataccactt ataacgccgc aaaaaaacaa gggactgtga caaaagtcgt gtcaaagtcc
     5761 cttgtttcga ataaatggtg ttcaatcagc tgaccttcag cattaactca aaaaacggca
     5821 aaatatgagg agctattttt tcgtttgttc ctctaatact caggtcaaat cgctgatttt
     5881 acaacctctt ccttaaacgg tgttctcctg ccaacacctc ggtcacaagg cacaatagtc
     5941 aacaaacatg agaagttgtt ttttgaaatt gctccttgtg actcggagtt aaacggcagg
     6001 ctcactacct ctttcttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccagca
     6061 aaacgaaaaa tatgaggggc tatttttgtt tggctgttct tattacttga tgcaggacag
     6121 ctttttcaca acctctgatt cacggtgttc cagaagtagc ttctgcgaaa aacaagccga
     6181 aacttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctgac
     6241 cacttctgtc acaacctctt gtaacaagta tttctatttt aaggctgaac cactgtttct
     6301 ggttcagtga tttctttgtt tttgtctcga cgagcaattg ctggcaagat catacctaat
     6361 aagatcaaga caattggtgt gatgatattc gtgaataatt ggaaccacca tgctttagga
     6421 tcagcagtat aatctacttt tggcaccatt cctaggatac atgcaaacgc agtgaaggca
     6481 aagcaccaag caccaaagat aaaaccgatt tttggatttt taacaaattt atattcagaa
     6541 ttgaatttct tataagcttt attcaacatc atatatgcca agaacaccca taggtaacgc
     6601 attggcatga caactgagtt caagttcgtc aaccatttta ctaattcatt catatctttg
     6661 ataccaaaga tcggcaacaa aataatgatt cctactagta tacctgtcag aagataacca
     6721 ttcaccaatg tacctttacg attacgttta cgtagccagt ttggtacaaa ttctggatcc
     6781 gcatctgcta acaagatttt tagtggtgca tcaattgaaa aggctaatgc ggagatttgt
     6841 ccaatcatgt ttgtcaatgc gtaaatgatc atcaatgagt taccgatacc atagtaatta
     6901 cctaaaattt gaaaagcact gtatgcccca tttgccatca agtctttagg aatattatcg
     6961 ctagcaaaca gcatacccat tgcgactgag cctaatacag cacaaatccc taccattgct
     7021 gctaagaaga tcatcccttt aggaaattcc tttgcaggat ttcttgtaga gttgacataa
     7081 ggggatattt tttccgctcc tccaactgca aatactagca tcgaaacggt tgtgaaataa
     7141 ctgaaatcaa atgttggaat atatgttttc acttgattca tatgtggtgt ggcaaattcc
     7201 atcgttggat tgatgaacgg tgccgttaca gctaaaagaa taaataagat cgacatgacg
     7261 aacatcgctg ttccggccag tccgccaatc actttcaaag tagaaagtcc ttttgttgat
     7321 aaatataaaa aggcaagaaa tataataagt gaaataactg ctaccatttg tactgacatc
     7381 gtatttacga tatttccatt tccttggact gcccaaccgc cagcaatcag gattgcttga
     7441 ggcttttgtg ccaaataagg aatatggacg acccagtaag tccaagcggc atagtatgcc
     7501 agtcgtttat tagatgtcgt attttcgacc catgaactga cgcctccttt actatccttg
     7561 aaggctgacc ctaattgtcc aacgatcaat gcgtatggaa taaaataaat ggccaaaatc
     7621 aatagccaag aggtgacaac tgatactcct tgctgagcat agttattaac tacattcccc
     7681 atgccccaaa ccatgttaaa tgcaattaac gcaacagtaa accagcgtaa ttgtttgttg
     7741 ttcattcgtt ctctccttta tgataaaaat ttgttatcca gatgtaatca tattcaattt
     7801 ttaacaaact tacaagacag tgttatttta tgtgtgtatt cttttattta atacacatcg
     7861 ttttttcata ttttttccat caaaaaaata agttattttc ttttatttca tttaccttat
     7921 tgaatttcaa gctattttga attttctgca aaattaaaaa cattagttat tttataatcc
     7981 tatctatttt ctttacattt ttcattaaga aaaggatata aaaaaaagag gacgttcatt
     8041 cgtcctcttc attgatcaac gtttattttt tacatgcaag cttcgcatgg cattcaaaac
     8101 agctaatact gtcaccccaa catctgcaaa tactgcatct cccattgatg caaaaccaaa
     8161 agcacctaag gcaagtacca aaatttttat cccaatagca aagacaatgt tctgtttgac
     8221 gattttcaat gttttctttg ctaaatggat tgcttctgca atcttcgatg gttgatcatt
     8281 catgatgact acatctgctg cttcaattgc agcatcgctt cccaatccac ccattgcgat
     8341 tcctacatct gctcttgcta gcaccggtgc atcgttgatt ccatctccga caaatgcggt
     8401 ctttttattg tttctttgta agatttcctc taaccgctgc actttatctt ctggaagcaa
     8461 ttcgctatat atcttgtcca cgcctacttg cttcccgata tgatcagcaa tttttttcga
     8521 atcgcccgtc aacatgactg tgttcttcac accagccttt tttaattgaa ccaatgcgtc
     8581 tacggcatct tctttcaagg tatctgcaat aacaagataa ccactgtaac tttgatcgat
     8641 cgctagataa agcaatgtac cgatttcttg acttgaagga aaagagattt caaatctttc
     8701 catcaatttg tgattacctg ctaatacttg tttgccatca acttcagcta agatcccttc
     8761 acctgcaaat tcttggatat tagctgttgg taaaagcgga cctgcgtagc cttctaaaac
     8821 agattgagca atcggatgtg tagaaaactg ttctgcactc gcaacatatt gcatgaatat
     8881 ctttggatcg atttttgtat cgatcgtctg gatcgaaaag tcacctttcg ttaatgtgcc
     8941 ggttttatcg aataccactg tctcagtttg tgcaagcaac tccaagtaat ttgaaccttt
     9001 tactaataca ccgattttac ttgctcctcc gataccgcca aagaaactaa ggggtacgga
     9061 gatcactaat gcacatggac atgagatcac taaaaatgtc aatgctcgat agatccattc
     9121 agaaaacgcc gctccagaaa caacaagtgg aggtaaaaca gctaataaaa cggccaatcc
     9181 tacaacgact ggtgtgtaat agcgcgcgaa tttagtaatg aaattttcag ctggtgcttt
     9241 tttactgctg gcattttcta ctaattctaa taatttgctg atagtagaat tttcataaga
     9301 tttttctact tgaactaaaa atggtttatt tttattgata aatccactta atactgtttc
     9361 accaacatat acagatttag ggactgattc tcctgtaagt gctgacgtat cgactaatga
     9421 ttctccttcg atgatcgttc catctaacgg tacacgttca ccaggcttca caagtacaaa
     9481 ctgaccgatc tgcacgtctt cagggttcac ggtcatcaat ccttccgtcg tctgcacgtg
     9541 agctgtttct ggacggatcg ccatcaattc gcgaatcgat tttcttgaat gactgactgc
     9601 caatccttgg aaatactcgc cgatttgata aaatagcatc actgctacgg cttctggata
     9661 ttcaccgatc aacatagcgc caatcgtagc aacagacata agaaaattct catcaaagat
     9721 ttttcctttg acgatattca tcactgcctt cttcactaca tcatatccta tcagcagata
     9781 aatcaataaa taccctatca agcgaattgg ttcattaaaa tcaaataata gcaataaagc
     9841 gatacctgca agggaaaata aaatccggaa cagcgtattt ctctcttttt catttccatg
     9901 ttcagatact ttttccttat ctatttctgt tactttgaca tctggttcta attccttcac
     9961 tacttttttt atttcttgtt caatcgtagc caaatgatct tcctctgcgt caatcgttag
    10021 ttttccagaa gtgaagttta ccgttgcttc cttgactcca ttgatcttct gaactccttt
    10081 ttcgattttc attgcacagt tcgcacaatc taaaccttct aatctgtaac ttttcatttt
    10141 aatgacctcc tcgcctcaac atatgaatat ctcttcataa ctaattataa atgaacggtt
    10201 attcatatgt caaggtatcc gaaagaaaaa atgaaaaaca tctgcatcgg aaaatttctt
    10261 ccatacagat gttttggctt attctttctt tttcttttcg atcattgcca ctgctcttat
    10321 ccaacccgca cttgccttct tgatcttgac aggatagcaa ctaagtttga agcctgttgc
    10381 tggcaatttg tctaaattca ttaatttttc gataggacaa tatctttttt caatccctgc
    10441 aaaatgtcct tcccagatat tcgaagctcc actacgcttt caaaaatata gaaagagttc
    10501 tttaatgaaa attatttcaa ctttccataa acagtaaccc catataaata aaagacgtaa
    10561 aagtcacatg gaagaactta tacaggagaa cgcatagagt caggtgaaat acatgtatcc
    10621 cacctgactc tatgctttat ctaaccttta ttattctctt ttatacaatt tctgcaccga
    10681 atggcatcaa cgccaatcga gcaagtttga aagattgctt ggcaaaaggt atccctatga
    10741 tcgtgataca tagaaggatg ccgctgacga catgtgcgag agcaattggt aggcctgaaa
    10801 cgatcagcca gatgatatta acaatcaatg acatgccaga ctggtgataa attacttctt
    10861 tgccaaaagg cgcaaaagaa agggaggcga tcttaaaaca ttgcataccg attgggatac
    10921 ctatgatcgt gatacaccaa agtatccccg ctgctaacca gctaagacca ccgattagtc
    10981 cgccgaatat aaaccagatg acatttccta aacaactcat tgtatttctc cttctattac
    11041 tgtttttgat taaaactggg caaaaaatga ttttattctt ctttttttag cttccagtat
    11101 caaatattct gcaaattttt tttggatttc ttccgtattt tcttttgtta ctaatgtgtg
    11161 ttggattagt tttcctgatg gtcgctgatc caatcgttct tctgactgtt gcacgtccgc
    11221 ttgcgcaaat ccgataatcc gtttttcttt tgttacagca acgagcaata gtttattctt
    11281 atcatttagg tcagctgccg tttttgcttt tacgaatgat tctggatgat cagtaatcag
    11341 ctgattgatt tgaggtagat cttcttttac tgcccaccgt atttccatca tttctcactt
    11401 ttctttcgct catttttatc tccactaaaa aaatcgactg cggcaattgc atctatccag
    11461 ctttgtgcaa tgatctcatg tccgccaatc gttgggtgga ccccatcttc tcttgtatat
    11521 ttcgaaaaac cataaacaat ccctaaagca ttgaatatac catctaaagg aaccagcaat
    11581 gcgccatatt ccttagcaag tttacgaaca atttggattt tagggtctaa gtctttacgc
    11641 cagccatgac ggtcgtcggt tataggaagt acaaacggct ccatcaagat gatgttgcag
    11701 attcccactg tttgaagttc atttagtaat tttcgataaa cggattcaaa ttgctgagca
    11761 gatttctcag ttccgaatat agcctgatcg ctagtattat gccaggtatc attgattccg
    11821 atcaaaatcg atacatagtc aggttgtaaa gctaaacaat cttcttgcca gcgtacttgc
    11881 agatctgcaa ttttgtctcc tcctatccca cggttcatgc attcaaattc catcgttgga
    11941 tattgggaga ttagttttcc ggcaatcaaa agtggataac ctttacctag atcagttgct
    12001 tctgctcggt ctcttcctgc gtctgtaatg ctatcaccga taaataatat acgttttttc
    12061 atttgtcaaa aactcctttt tgaataaaac gatgattttc ttccttatat tatcccataa
    12121 gccctatcaa gacgaaagag aaaatatatg tataaaaaat gacaccagcc tagtcccttc
    12181 aaacaattga atgaacgctc atcaagtgtc tagtttttta tgctattttt ttcttaacgt
    12241 gccggattcc ccttgattcc ttcgttgttt ggtccagaga gatcgatcac acctaagctt
    12301 ccgtcaatca gaccactgat gacgccatca gaacatatat ttataggctc atctaagact
    12361 tctagtaaat gtccctttac taatatctct tctagattgc ttgggataga ttggtcataa
    12421 ctttatctgg tccgatgatt tcaagggtga attgaactta catatggatt attgcatgct
    12481 gaaaatacgg acctactcca tcttcgaatg ttactattag tttgttttca ggtgctagat
    12541 gctgctttat ttcaacagca gaagcatcat caaatcagat ttccatttga attaccttct
    12601 ttgtaaatgt ttgattgatt gcgatttcgt tatagaacct tgtgaatcaa atagcaattt
    12661 cttttgcttt cttctcttgt ctgctggaaa cttcctttat cccgtatttt aaaaaaagaa
    12721 ctgcgagagt tcgcagttct tttttagaat aaacggtgct ctccggccaa ctcctcggtc
    12781 acaagtcaca atagtcatca aacatgaaaa actgtttttt gaaattactc cttgtgactc
    12841 ggagctgaac ggcaggcgca caacctcttg atataaacgg tgttcaatca gctgaccctc
    12901 gatattagct aaaaaaacgg taaaatatga gaagctattt ttccgttttg tttctctaat
    12961 actcaggtca aggcactgat ttcacaacct cttccttaaa cggtgttcaa aagccagttt
    13021 ctcggtatta agccaaattt atgcaaaaat gtggaaagcc atttccacaa aatttttctt
    13081 aatactcgaa actaaacagc tttttcacaa cctctccact aaacggtatt caaaagctta
    13141 catctgcggt aataagtccc gccaattcaa aaacatgaac agctgttttt gcttggctgt
    13201 tctaattact tgatgcagaa cagctttttc atcacctctt atggataaat tcggttcaac
    13261 aaacgtggga atggaatagc ttcacgcaca tggtcgatac cagcaatcca agtgactgtt
    13321 cgttcaaggc ctagaccaaa accagagtgc ggaacagaac cgtatttacg tagatcaaga
    13381 taccatgaat attctttttc atccaaaccg tgattacgga tttgttctag caagaaatca
    13441 tagtccgttg cccgttcgct tccgccaata atttcaccgt aaccttctgg tgcgatcata
    13501 tctgcacaaa ttaccacgtc ttctcttgtt ggatgtggtt tcatgtagaa tggcttgata
    13561 gcttttggat agtttaggat aaagacaggc tgttcgaatg aattcgcaat gaacgtttca
    13621 tgaggtgaac caaagtcttc gccccattcg atgtcatcaa atccattttt cttcagtaat
    13681 tcgatcgcat catcataagt aatacgaggg aatggcaatt ttgtataagt ttttaagact
    13741 tctttgtctc gtcctagtac atctaatgcg tattcgcaat gatctaaaac attttgtact
    13801 aagaatgcta catattgttc ctgtacttct aaactttctt cttgatgagt gaaagccatt
    13861 tctggttcga tcatccagaa ttcaatcaaa tgacgtcgtg tttttgattt ttcagcacgg
    13921 aaagtcggac cgaatgaaaa gacttttccg aaagccatag cagcagcttc catgtataat
    13981 tggccacttt gagataaata agctttttga tcaaagtaat ttgtttcgaa tagatccgta
    14041 gtgccttctg gtgcggaacc agtcaagatc ggcggatcga ttttgacaaa atgatgttga
    14101 ttaaagaatt catacgttgc acgaatgatt tcatttctga tctgcataat cgcatgttgt
    14161 cttgaagaac gtagccataa atgacgatga tccatcaaga agtctgttcc gtgttctttt
    14221 ggtgtgatcg gataatcgtg gctctcgctt accacttcca catttgtaat tccgatttca
    14281 taaccaaatt ttgaacggct gtcttcacgg atttctccag ttactaacac ggatgtttct
    14341 tggtgcagat ttttagctgt ttggaaaact tcttccggca cttcgctttt tacaactaca
    14401 ccttggaaaa aggctgttcc gtctcttaat tgtaaaaatg cgatttttcc gcttgatcgc
    14461 ttatttgcga cccaagcgcc gattgttact gtttctccca catggttttt cgaatcgatg
    14521 atttgaattt gttccacgta tgactctcct tttatattcc ttgaatttct tcaggattaa
    14581 ttttgacttt tactctcaat aaattgcttg attctgcgta ccgcttcttc taacgtagcg
    14641 cgatcagtgg cataactcat gcggacattt tctggtgccc caaagccttc gccagtcaca
    14701 agcgctaccc ctgtttcttc taaaagatct tctacccatt gtgtgacatt ttcatattta
    14761 cacatgcgta gcgtttcttt tacattagga aaaagataaa aagctccttg tggcttttca
    14821 agagaaacac ccggcagttc tgccacaagc ggatataacg tattcaggcg ttcttcaaag
    14881 gcgttccgca tttcttccac tgtatcttgc tcgcctttca atgcttcaac agctgcatat
    14941 tgactgactg ctgtcggatt gctagttgat tgggaagcaa cagcgatcat tccattgatg
    15001 atcacaggat ttcccaccgc ataaccaatg cgccagcctg tcatcgcata tgttttagac
    15061 acgccgttga tgatgatggt ctgatttttg attgcttctg aaatcgttgc aattggagta
    15121 aactcattgc cattataaac taaacggcca taaatatcat cagcaactat caaaatatca
    15181 ttttttactg cccattcacc gattgcctgc agttcattct tgctataaat cattccagtc
    15241 ggattcgatg gagaattgat gattacggct tttgtttttt ctgaacgtgc ttgttctagc
    15301 tgctcaacag taactttcca gctattggat tcttctcctt tcaaaaagac aggaagtcct
    15361 tctgccagtt ttacttgctc accgtaactg acccagtaag gcacaggaat gatgacttca
    15421 tcttgcgggt caaggatcgt ttggaaaagg gtatacaaag caaatttcgc tccgtctgtt
    15481 acgactgttt gtgaaggttc atagacaagt ccatagtttt tcttcagata atcaacgatt
    15541 gcctgtcgaa gctctgggat tcctgctgtt ggtgtataat agctagcttt cccattgcgg
    15601 attgcttcga ttgctgcttc ttggatgttt tctggtgtcg caaaatccgg ttctcccaca
    15661 gtcaaactca gcacatctct gcctttggct tttaatgcct tggcctttgc cgcagctgcc
    15721 aaagtgacag acggttctaa tcgttttgtt ctttttgata actccatccc attcattcct
    15781 ttacctttta aattcccttg attgtcttga cttcatctcc agattcaaag ccaatcaggt
    15841 aataattcag tttcccattt gtttcttttc ctactacttc ccacacaggc tgatcatcat
    15901 acatccctaa agcagctttt tcgatttgga tttcaggatg ggccgcagca attgtctgtt
    15961 ttgcttcatt ttcagtcagt ccctttgttt gatccaatac ttttactttt tcaccagatt
    16021 taggaatgat aacggcgatt tcttttcctt tatcatttgt acctgtcagt gaaaagtatg
    16081 tcttctttcg agtaaaccaa taaaaatgat cggcttcctc aagatttgca tatttctttg
    16141 cgatttctac tgcttctttc ttcgcctgca ccgccggacg actggaacgc aagtaaaaaa
    16201 tcgagctgat cacgatgacc gctaataaaa atacgatcaa gccaagtaac acgcgattaa
    16261 tcgttttttc ctttgtctgt tttttcttca agggtcgtcg ctcctttatc ttcattcctt
    16321 ttcattatag cagattttaa ttatgaaaaa agacagctcc tctaacttcc ttcttcattt
    16381 ttctttaaga attcatggat atcctgatag atttcctcca tagctagctc tttgatcggt
    16441 acttttttcg gtaatgcatg gatgatccgt gcaccatatt ttgcagtaac tagtcttcga
    16501 tccaaaataa gcaatacgcc acgatctgtc tccgtcctta tcaagcgtcc taatgcttgg
    16561 cgtaacttca aagctgcttt aggtacggat tcctggtaaa aaggattgat cccctctgat
    16621 tctaaataag cgttcctagc tttgaccatc gggcgaagcg gattatcgaa gggtaaacgt
    16681 gtgactacaa cgatctgcaa agcatctcca ggcaaatcta caccttccca aaaactgtca
    16741 gcgccaaaca atacgctttt ttctgacaaa atgaagcgtt tcaaaagctt ctcccggctt
    16801 ccgccaaacc cttgagctag tatttctcgt cctttttcta gcatagacag atgcattttc
    16861 tgatagacct tctgcaaaac atcatgagaa gtgaataaca caagtattgg ccgatcttct
    16921 tgttcgatca gacctgtaag tgctgtctct aaataatcga tatatgcttg attgctgact
    16981 tgatggacgg caggtgcctc ttttggcaca tagatccttg cctgtttctc ataatcataa
    17041 ggagaggcaa tcactttaag aggtgctgct tcaatgccaa gccgcttaga gagatagtgt
    17101 cgattagggc cgatcttcag cgttcctcca atataaagaa tacgatcata tcgaggatac
    17161 caaacagtcg acggcaacat agccgcttga aaatcatgga gatgaaaaat catctgctgc
    17221 gctgtgttcc caggaacgaa ccaatggatc aaatgatctc gccagtcttc cagccattga
    17281 tccatcagca agtactgctt gtctaattga tcaaataagc tatataaact tgctaaatcg
    17341 atccgcatct ggtttgtcca gctttcttgg ataatctcaa aagtcagacg catttgtgac
    17401 tgtagctgct ggatctcctg ataaaaaagc tgcaggtgat caatggctgt cccagattcc
    17461 agtggcagct gatccaacat ctcttttgtc gtcatgactt cttctggata ctgtccgtta
    17521 ggttgcttgc cgctcactaa actcattaat ccttctgcca tacaaatctg tgcttcgcat
    17581 agcgcagaaa gttcttctcg ataaatcgat aaccagcgta aggcttcatg ttctttcggt
    17641 aaatagcttt gtattcggtc aaacagctga tttggttctt ctaattgctg gatttgttta
    17701 tggaaatagt taatacttaa tcgtttgtca tttacttttt cagcgatttc cggcaaatga
    17761 tgtacttcat cgatcaacaa aaatggacta gctggaagca atggttcttt tcgctgtgtt
    17821 tcttgtatta aaaacgcatg attgacaatc aaaaaattac tttgcctgat tttcttttgc
    17881 aagaaacgaa caaagtcttg ttcgtaaaat gactgatttc ttgctaaaaa tccagtgcct
    17941 ctgtgcgcga tatctgcaaa gaatgaatgg ttcaaatttg ttaaatgtaa ttcatccaaa
    18001 tcaccggtct tcgtttgcgt cagccaaact aagaccgcca tttgatacaa agcatattgt
    18061 ttttgttctg gcggttccac aagtgtgcct ttaaaacgct gtaaatcaat atagtggcga
    18121 tagcttttga taattacagg ttgtatgggc tgatctagca attgattcag caatggaatg
    18181 tctttttcta tgatctgctg ctgcaaaact agcgaaacgg tactgatgac agcgggtttt
    18241 tcaggtgtag ccaaataact caatggcagc agataaccga ttgttttacc cattcctgta
    18301 gctgcttcga tcatcaaatc ttttgattca tcttttgtga aatggtcgta gaccgcattc
    18361 atcagtctgt tctgttcttt tcgatacatc agtgttttac caaacatttt ttcttttgct
    18421 tgtttttttc ttggatatgt ccgctcgcca taatggacgt atatgaatag ttccacttct
    18481 tttttctgca aagctagccc atcgacgatt tctaatgagg gatcaagtgg ctctggtttt
    18541 tctttcattt cttcaatcac atgataaatg aaacgactcg tatccatacc tgtgtgtcta
    18601 cttaatcgcg caatctgctc taacgtgatg attggcaatt ttctcatccg ttcttcgatc
    18661 agcaaaagaa gttgacccgt cacttcggca tcactatctg cctgatgagg attctcatga
    18721 ataaatccaa ggctttctga caaatcagct aagcgaaagc ttggttccgt cggcaagaaa
    18781 atttgtgcaa gttctactgt atcgatgcct ggtatcttca aactaggaag tccgcatcgc
    18841 atgagttcat ggttcaaaaa attataatca aaataaatat tatgcgcgac aaatatggtg
    18901 tctgccaaaa gattgtaaat cgtttgggcg acatcttcga aataaggcgc tttttggacg
    18961 cgttgattcg tgatccctgt taaatgctgg atttgttttg aaatcttccg ccctggatga
    19021 atatcgatcg aaaaacgtga agtgatccga cctgattcaa tcatgacgca gccaaattgg
    19081 atgatccgat cttcttttgg attcgtccca gtcgtttcga tatcaacgac tgcataagtt
    19141 cttggtttca aaatatcttc ctcttctcct gcctctaatg ttcttttgaa attatactac
    19201 aaagtgcaga aaaatactct catcgctttt taaagaaaat agacaaaaac gcccagacac
    19261 gcaaatgtct gggcgtttat tttttagtat aggttaatta agctttagta acgtttgttg
    19321 cttgaggtcc gcgttggcct tcttcaacat cgaaagttac tgcttggcct tcttctaaag
    19381 ttttgaatcc gtcgccttgg atagctgaga aatgaacgaa tacatcgttt ccgttttctg
    19441 cagtgatgaa tccaaatcct ttttctgagt taaaccattt tactgtacct gtttccataa
    19501 taaaaatcct ccttgtgtat caacacatat tttgcaatta cttgaatggt gtatatctgg
    19561 aagatgttta tttgaaacaa gctaccacag attaccgaac aaaaactact cctatagtat
    19621 atcataccgt ttacaaaaaa gctagagttt ttcgactttt tttattaaaa aaagttttct
    19681 cagcgattac ataaagtgaa aaaccgaact ttttttaaaa taaacgacat attgttcagt
    19741 tggtgttttt ttgctctgat gttcttcttt aaactaaaaa aattattctt tctgactact
    19801 tatcggttct gtttcaacgg tcgaggctgg ggaagattct ttagtaggtc tgatgttctc
    19861 atggtatttc tgatagccta tgacagttac cagaagaaca aggcaaacca atacgatcaa
    19921 cgagattagt ttttcttttt tgctcatatc tatacctcat aaataacagg atgatgtcca
    19981 tcatatttct gagtatgagt aaaagcaaaa gctgcagctg tagaatgtaa gaaatgccag
    20041 caactttcat aatcacaggt cggacagtac caaaagtaac caaatcttgg ctgcaaagac
    20101 cgttcttctg tttcaggaat cgcagaatca agatctgttg tctgtacata aacatttttg
    20161 tacagacgtg tgcctgtaat aggagaccgc tgtgtttctt cagcaaaaac tggctgactt
    20221 gttaaactta gggatagaaa cagcaaacac cataacagtc tttttttcat aaagacctcc
    20281 ttatcgataa gtttttccca attaaaatca tatctcaaga acgcccgtta ttcacatttt
    20341 gttcataaat gatgtttttt gtatcataat cgtcaaaaag aggtcgtgac cacgtcacaa
    20401 cctctttttt aaacggtgtt ccagaagtag cttcttcgga aataagtcga aatttcacaa
    20461 aaatttgaga aataattttt gtcaatctct tcttatttct tgaagctgac cacttctgtc
    20521 acaacctctt ccttaaacgg tgttcaaaag cttgcatctg cggtattagc tcaaaaaacg
    20581 gaaaaatatg tgaaactatt tttccgtttg tttctctaat actcaggtca aaacactgat
    20641 ttcacaacct cttttaataa cgaagaatcg ctgtcagact cttttcatct ggcgcatctt
    20701 tttgatccaa aataaacact ttcccgccat taatgatcac atcatctgct aatgcattca
    20761 acacttgacg ccgatcatat tctgtttcag gatcttcacc gaaaccatca gctaagtttg
    20821 acgtagcgat aaataaatgt gacacttttc cttctttcgc agctggaacg atatcaacta
    20881 actgatcgat gaatttctta tctaagagtt tattgtattc ttttgattct tgagctgcga
    20941 gttcacttga cagcttcttc gccccttctt cgatatctct aaaggatagc tgcgcaggag
    21001 aagcagaaat cgcaacgtct gcacaataat agggattttt agcaattttt ttgaacatcg
    21061 tctgattttc tggtaatgca aataaataaa tcggccattg ttcaggattt tcgaaagaat
    21121 ccttcaagta cgtatcaaca gcttggtaat agttgaccca atcgatctct acttcttcat
    21181 cttttggatt tacgccatgg aaagttactc catctcgggc tccgcctcct ccattagaag
    21241 agaagttcaa accgccacct gtcagttcag atcccaatgc agtaacgaca tcaaccggtg
    21301 ccccttctgg tagagatact tcttttactt gtttgttgct gacctcatac aatttcatgg
    21361 agtcgcggtt caatcccaat aaataataag aatagttgaa ctgcccattt ttgataatag
    21421 ccagtaaata aggaagatca cttacatagt attgatcgtc taccgggata ctcaaacgat
    21481 ggatataggt ctggtcagca gttataatga ccgctacact cgtagttgca ctacgccaaa
    21541 acgaaggatc tcctaacaaa ttttcaattt tttcttggaa cggggaccag tcatgttcgg
    21601 aatatttttt ctcaaaacgt ttctttgctt ctttcgcaaa atttttgaat ttgatctgat
    21661 ctttttccac atcttgatgg gcgacatgcg tattcagcat gatcgtgacg aatggtcctt
    21721 tagcgccttc tgaagtcaat tgtgtcaata attctttatc cttttttgcc ataaacgtac
    21781 ccctcctaaa aaaatcattc ctttgtttct atctaaagtc taccacaaca ctatttttcc
    21841 atacaataaa acgtatctaa aaaaataaaa cggtttctac ggttttaaat ttagctattt
    21901 ttttaagtta tcttcataat ttcctcaatt atttagcccc agtcttcaac tattcttcat
    21961 gaaatgctga taaactaaga aaaagaataa aagaggtgga tcttatgcat ttgattatga
    22021 ttttcagttt attaagtatt atcagtttat ttgctttcag cgcttcccgc ttattagatg
    22081 cggaaacaca gcctattcct gtaaaagtac gtaaaaacga ccgctaaact tccataacgc
    22141 gcgttcttat cctaaagttt tttcagaaac attgaaactc tctcccctct ctgataaaat
    22201 tttaatttgt agcgaaacaa attaattaca aggagatcgg atatgtccat aaaaaaaaca
    22261 cgtctagtcc tattattggc tagtctcatt ctttgccttg cttcttttct accagctgtt
    22321 gctgtgcaag ctgaagatac gttcaaagta aatgcaaaag cagcttttgc tgtagatgcg
    22381 caaagcggta agattcttta tgatcaagat ggagaaaaaa ccatggggat cgcttcaatc
    22441 acaaaaatca tcggtcttta catcgtcctt gatcaagtaa aagaaggaaa actgtcatgg
    22501 gatgataaag tttcgatttc agattatgca gaaaatttga gtatcacccc agatttatcg
    22561 aatgttcctt tgcataaaga aaacacctac actgtcaaag aattattcga ctctgcaatc
    22621 atccagtcag ccaatgcttc aatggtggcc ttggcagaaa aaatctctgg cagcgaagct
    22681 aaattcactg aacgaatgaa agaacaattg aaagattggg gaatcaaaga tgcaacaatc
    22741 gttaatgcat caggattgaa caactcttat cttggcgaaa accgaccaga aggcactgga
    22801 gaaaacgacg aaaatcaaat gtctgctcaa gatgtggcca tcgttgcccg ccatttgatc
    22861 ttggatttcc cagaaatact ggatgtatca agtactacga cccaaatgtt tggcgaaaat
    22921 acgcaatcac cagtggaaat ggtcaactgg aactggatgc tcccaggatt cgttaattac
    22981 aaggaaggcg tggacggatt aaaaactggt acgactgagc ttgcaggtgc ttgtttcgtt
    23041 ggtacgatca ctaaaaacga tcaacggatc atcactgtcg tattgaatgc ggacggccat
    23101 gcggaaaacc cgagtgcccg cttcaatgaa acagaccgtt tgatggacta ctgctatgac
    23161 aattggtcag aaaaagagct aggaaaagct aacgcaagta ttcctagtct aaaaaccatt
    23221 gatgtaaaag acggaaaaga atcaacagtt cctgttgtgc ttaaaagccc tgtaaaagta
    23281 tgggtacgaa acgatatgga tactggcaaa ttaacgatca cgccaacact tgacaagaag
    23341 caagtcactg acaatgagat ccaagcacct atggataaag gtacaaaaat cggtaccgct
    23401 acgatcacct tggcagacga taaattaggc tatttagaag acaacaatgc accttcaaca
    23461 gagatcatta cggataaaac agtggaaaaa gcgaatatat tcgtgattgg ctggcgacgc
    23521 gtcgcagaat ttttcggcaa cttgttttaa ttgaacaata agaaaaacat ctttccatcg
    23581 gaaagatgtt tttttgcttt ttctagttta aataacagct tttttcatct attttcgtta
    23641 tactgtataa gaaaaaggag ttgaatttat gaatctaacc agagatctga tctttttagt
    23701 tctctatctt attggggtat tctctatcgt ttattggcga aaacagaaga aggatccttc
    23761 cttgttcttt tacggcagta cgtggacatt tacggtaatc ttaacttatt ttgtcgtgtt
    23821 ggaaattttt tattcgacct tttatttttt gattccattg ttgttcttta gtatctttgc
    23881 tttttcttat ttcacagaaa aacgaaggct gctgaatggt cttttattca atgttttcct
    23941 catcagtttc ggcatctact tgtttgtctt gctgtatgaa acgcaaaata ttttccttgg
    24001 cggactgatc gccttgatca cgattccatt gctacttgtc cttttatttg gtatttatgg
    24061 attgattgtt tttctttttt ggaacggggt cacagtttta cgtagagaat cgcattcatt
    24121 agctaatctt ttaacgttga tactagccat ttttcttaca ctgtttcttg tttttgactt
    24181 tttcttgtta aaatatttgc cgcaatggat aaatgctttg tttttctgcg ttcccctgat
    24241 cttgatctat ctatttatcg tattctacaa ctttttgact gtctcattct tgtatcagtt
    24301 caaccggcct cgatacaatc aagacttcat cgttgtgtta ggcgctgggt tgatcaatgg
    24361 agaaacagtt tctcctcttc tagccaagcg aatcaataag gcaattgctt tttatcgggc
    24421 tcaaagccgt gctacattaa atccgcccat cttattgatg tctggcgggc aaggagcaga
    24481 cgaaaaagta ccagaggcca ttgcgatgaa acaatatgcc atggaacaag gaatccctga
    24541 aagagacatt cttgtcgaaa ccaattcgac aaccactttg gagaacatgc tctattcaaa
    24601 ggaaatcatg gatcagcaaa tgaaagggcc ataccgcgcg atctttagtt ccaacaatta
    24661 ccacattttt agagccggtc tttatgcgtg gcaagccaaa ttgaaagcaa atggtattgg
    24721 tgcaaaaaca gctttctact acttgcctaa tgcgttttta agagaataca tcgccatctt
    24781 gatgatgaac aaaaaaagac atatgatcat ttgcggattg cttttcgcag gctccgcatt
    24841 cttatcgctg attactttac ttttctaaaa aaacaaggtg tgacaaaaca tatgtcacac
    24901 cttgtttttt tctttcattc tcttaactat tggcaaaaag agtatccctt ttttgaccgc
    24961 tacttgctga gcagaataaa taccgctgtt gcctgaacac ataaagctga tcaagcagat
    25021 cataaagaag tatactgccg cttgtgaacc gaacaattcg atccccatca caaagcaggc
    25081 aatcggtgta tttgtcgcac cagaaaatac tccgataaag cccaatcctg caagaaaagg
    25141 aacagaaaca tggagcaaag gcgctagtgc tgcaccaagc gttgcaccaa tttcaaacaa
    25201 tggtgtcact tctccccctt gatatcccgc gcctaaagac aaaactgtga agaataactt
    25261 cccaataaaa tcatagacat gtgcctgtcc attaaatgat tcttgaagta acggaagact
    25321 caatccgaga taacgttgtg tttgcaaaat caatgctgct gccacaacta cagctccacc
    25381 tatcgtattt cgccaaacag gatgaggaat ccattgtgca tatcgcgctt ttaaaaagac
    25441 gatcgaacgg ctgaataccc aaccaatcaa accaaaagca atcccagcaa caaaaacttt
    25501 gaagaacagc aacatactcc attcaggaat cacacccatt tggtaatgta gatgagaaac
    25561 accatagctt tctgtcatga aatttgcaaa cagtgcagca aagaagctag ggaagatcgc
    25621 ttctgttcgg actttcccga ttgccaacac ttctaatcca aataatgttc cagctaaagg
    25681 tgtgccaaat acagaactaa aacccgcact gattccactg ataatcaaga tttcccgttc
    25741 tgatttatcc aatcggaaca aacgtgctgt attatctgct aacgctcccc ccatttggac
    25801 tgctgttcct tcacggccaa cagatccccc aaataaatgg gtagttatgg ttccaaacag
    25861 tgtaagtgga ataagtcgca acgggatttt ttcttctcca ccatttcctt gatcgatcac
    25921 taagttgttt ccacgactag aaagaccgcc gtgatacgca tagagataag caaaaagcgc
    25981 accactaact ggtagtagat aaaggagcca aggatgtgat agtcggatat ctgtcacaac
    26041 tgtcaggcta tttaagaaaa aagcagacaa gctccccatg aatataccga gaatcgctgt
    26101 gatcaccagc cacttcagca tgtacactaa aatgcgtact ggactcggta attgtttttc
    26161 cataaaaaat tcctcctcaa taaaaaaacg cctactaaag
//
LOCUS       DAFELK010000038        26146 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFELK010000038
VERSION     DAFELK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.039"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(47..1078)
                     /gene="queA"
                     /locus_tag="LP433_001870"
     CDS             complement(47..1078)
                     /gene="queA"
                     /locus_tag="LP433_001870"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBL2006019.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1271..2446
                     /locus_tag="LP433_001871"
     CDS             1271..2446
                     /locus_tag="LP433_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2006020.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2450..3091
                     /locus_tag="LP433_001872"
     CDS             2450..3091
                     /locus_tag="LP433_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2006021.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3088..4005
                     /locus_tag="LP433_001873"
     CDS             3088..4005
                     /locus_tag="LP433_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2006022.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4002..4673
                     /locus_tag="LP433_001874"
     CDS             4002..4673
                     /locus_tag="LP433_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2006023.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5214..5702)
                     /locus_tag="LP433_001875"
     CDS             complement(5214..5702)
                     /locus_tag="LP433_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBL2006024.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5903..6169)
                     /locus_tag="LP433_001876"
     CDS             complement(5903..6169)
                     /locus_tag="LP433_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL2006025.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6169..6432)
                     /locus_tag="LP433_001877"
     CDS             complement(6169..6432)
                     /locus_tag="LP433_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2006026.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6908..7093
                     /locus_tag="LP433_001878"
     CDS             6908..7093
                     /locus_tag="LP433_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2006027.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7235..9058)
                     /locus_tag="LP433_001879"
     CDS             complement(7235..9058)
                     /locus_tag="LP433_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBL2006028.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9656..12361)
                     /locus_tag="LP433_001880"
     CDS             complement(9656..12361)
                     /locus_tag="LP433_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBL2006029.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12667..13614)
                     /locus_tag="LP433_001881"
     CDS             complement(12667..13614)
                     /locus_tag="LP433_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBL2006030.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13804..14073
                     /gene="rpsN"
                     /locus_tag="LP433_001882"
     CDS             13804..14073
                     /gene="rpsN"
                     /locus_tag="LP433_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL2006031.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14249..14611)
                     /locus_tag="LP433_001883"
     CDS             complement(14249..14611)
                     /locus_tag="LP433_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2006032.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14622..15743)
                     /locus_tag="LP433_001884"
     CDS             complement(14622..15743)
                     /locus_tag="LP433_001884"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBL2006033.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15759..16109)
                     /locus_tag="LP433_001885"
     CDS             complement(15759..16109)
                     /locus_tag="LP433_001885"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBL2006034.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16239..17750)
                     /locus_tag="LP433_001886"
     CDS             complement(16239..17750)
                     /locus_tag="LP433_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL2006035.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18072..19424)
                     /locus_tag="LP433_001887"
     CDS             complement(18072..19424)
                     /locus_tag="LP433_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBL2006036.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19577..20653)
                     /locus_tag="LP433_001888"
     CDS             complement(19577..20653)
                     /locus_tag="LP433_001888"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBL2006037.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGQNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20849..22594
                     /locus_tag="LP433_001889"
     CDS             20849..22594
                     /locus_tag="LP433_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBL2006038.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22874..23311)
                     /locus_tag="LP433_001890"
     CDS             complement(22874..23311)
                     /locus_tag="LP433_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBL2006039.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23295..24668)
                     /locus_tag="LP433_001891"
     CDS             complement(23295..24668)
                     /locus_tag="LP433_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006040.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(24990..25478)
                     /locus_tag="LP433_001892"
     CDS             complement(24990..25478)
                     /locus_tag="LP433_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2006041.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25500..26102)
                     /locus_tag="LP433_001893"
     CDS             complement(25500..26102)
                     /locus_tag="LP433_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL2006042.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7502 a         5557 c         4834 g         8253 t
ORIGIN      
        1 tttgtaaagc ttttttgtta ttcaaaacta gcggcttttc ataaccttat ttcacgaaca
       61 tcgcatctcc aaaactaaag aaacgatagc gctcttcaat cgcatgctgg taagcagata
      121 aagtcaattc tcttcctgca aaggcactaa ctaacatgac taaagtcgat tttggcaaat
      181 ggaaattagt tgagaaagct tctaccactt tgaattcata gccaggcgta atgaaaatat
      241 cagtccatcc gctgtctgct ttgatttctc cattaaattt cgttccaatc gtttctaatg
      301 ttcgaattga agttgttccg acagccacga ttttcccgcc atttttacgt acttggttca
      361 atcgctcagc cgcttcttcc gtcaaacggt agaattcact atgcatatgg tgttcttcaa
      421 ttttatctac gctgacaggt cggaatgtac ctaaccctac atgtagtgtc agatagacta
      481 attcaacacc ctttgcttcg atctcatcaa gtaattcttt cgtaaaatgc aatccagctg
      541 ttggcgctgc agcagaacca ttttctttcg catagacagt ttgatagcga tctgggtctt
      601 ccagacgttc tttgatatat ggaggcaatg gcatttctcc caatgattca agaatctcta
      661 gaaaaattcc ttcatactca aagtcaatga tccgtccgcc gtgttccaat tcttctttca
      721 ctactgcttg caatctgcca tcaccaaaag agattcttgt cccaactttg gcacgtttcg
      781 caggtttgat caatgtctcc cacgtatctc cttgtgtatt cgttagaaga aggacttcta
      841 aatgcgcacc agtatctggt ttttctccat ataaacgagc aggcagaact cgtgtattat
      901 tcataactag cgcatcacca ggctgtaact cttcaatgat ttcatggaaa tgtttatctt
      961 ccatctctcc agttttccga tccaaaacaa gtaaacgaga atgatcgcgg tcttttaatg
     1021 gtgtttgtgc gattaattct tccggcaagt caaaatcaaa atcttctgtt gttaacatat
     1081 cgtcactcac tttctatcat gtgcttcatc attctatcat gtttttcgtt ctgttggcaa
     1141 aatcagcact ttttcacttc tattttttgt tttcctaaat aaaaaaacta ccctatttgt
     1201 attttttcat tgttttaggc atactagtaa tagatagttc ttcattgaaa atagaaaaag
     1261 aggtggcacc atgattgaat ttcaaaatgt gtcaaaaatt tataaaggtg gaaaagtcgc
     1321 tgtagaggac gtcaatcttt catttgaaaa gggtgagttc atttgtttta tcggtacgag
     1381 cggaagcgga aaaacgacga cgatgcggat gatcaaccga atgactgatc caacacaagg
     1441 gaaaattttg attgatggaa aatccatcca agaaattgat ccagtggaat tgcgacgtca
     1501 gatcggctat gttatccaaa gtattggatt gatgcctcac atgacgatcc gtgaaaatat
     1561 cactcttgtc caaaaattgt tgaaagtcag tcaagaagaa cggaataaaa cagctgaaaa
     1621 aatgattgat cttgtggaat tgccccgtga gatgttagat cgctacccac atgaattatc
     1681 tggtggtcag cagcagcgta ttggagtcgt tcgtgccctt gcagcgaatc aagatatcat
     1741 cttgatggac gagccattcg gtgcgcttga tccaatcact cgtgattcct tgcaagacct
     1801 tgtcaaagat ttacaagagc gtttgggaaa aacgatcgta tttgtaaccc atgacatgga
     1861 tgaagcgatt aaactagcaa gccgtatcgc catcatgagt gaaggccgtg tgatccaatt
     1921 tgatacacca gaaaatattt tacgtcatcc tgcaaacgat ttcgtagaag agttgattgg
     1981 agaagatcgc ctactacaag ccaagccaaa tgcgacaaga gtcggcgaag ttatgctaaa
     2041 tacagcaatc acgattacac cggaaaaatc attacaagaa gcaatcaaac tgatgaggga
     2101 aaaacgtgta gatacgttgt tagttaccga taattcgaat gtattaaaag gatttatcga
     2161 tgtagaaacg ttgaataaaa aacgaggaaa agtatccagt gtcggcgaca ttttgaataa
     2221 acatgttttt tacgtaaaag aatccgccta tcttcgtgat accttgcaac gcattttaaa
     2281 acgcgggctg aaatacgtgc cggtcgttga tgaacagaac aaagtcgtag gtatcctgac
     2341 tcgtgcatca ttagtggata tcgtctacga tgtgatttgg ggagaagatc ccgcaactac
     2401 tgatgttgca gagtcagcta ctcctgaaga atctaaggag gtctgaccta tgcagcagtt
     2461 ttttcatcag cacggttcag aaattctctc aaaaggtttt gaacatcttt atatttcagg
     2521 acttgctttg atcattggta tcatcattgc tgtaccgctt ggtgtcttac tgacacgttt
     2581 tccaaaagct gccacgattg tgattggctt aaccagtgcc ttgcagacaa tcccttctct
     2641 tgctttattg gcattgatga tcccgctatt tggcgtaggt aaattacctg cgattatcgc
     2701 actctttatt tattcattat tgccgatttt acgtaatacg tacattggga tgaaaaatgt
     2761 cgattggaat tatcgggatg tggcaaaagg catggggatg actgagttcc aatccatttt
     2821 ttccgttgaa ttgcccattg ctatgccaac gatcatggct ggtattcgtt tagctgccgt
     2881 ttacgtgatt gcatgggcta cacttgcctc ttatatcggc gctggtggtt taggcgattt
     2941 gatttttagt ggactgaata attaccaacc agatctcatt ttggcaggta cgatccctgt
     3001 aacaatttta gcactattgg ctgattggct tctaggtctc ttggaacacc ggctgacacc
     3061 gatcgcactt agagaggaga atgaagaatg aaacgtatac taaaaatgac catggttctt
     3121 ttctctcttc ttatacttgc gagttgttcc ttccctggtc ttgccagcaa tacagatgaa
     3181 gacaccattt cgatcacagg tggaatcact tcagaagcac agatcttagc aagtctagtt
     3241 gccggaatgg ttgaacatta tacagataaa aataccgcaa tcatcaacaa tctggctact
     3301 acaactatca accatcaagc gatgatgaac ggagatgctt caatttcagc ggctcgctac
     3361 acaggaacag atttaacgac tacattgaac cttcctcctg aaaaagatcc gaaaaaagcg
     3421 tttgctaccg tgaaagatga atttgagaaa agatacggtc aaacgtggtt cccgtcctat
     3481 agttttgaaa atacgtatgt ctttcttgtt cgaaaagaca ccgcacaaaa ataccatcta
     3541 tctaaagtca gcgatctgaa aaatgtagcg gatgaattag tagctggtgt agatacttct
     3601 tggatcaatc gtaaaggaga cggttatgac ggcttccaag aaacttatgg cttctccttc
     3661 aattcgatat tacctatgca gattggactt gtttatgacg cagtcgaagc aggaaaaatg
     3721 gatattgttc ttggctactc tacggatgga cggatcgcca gttatgatct agtcatgttg
     3781 gaagatgatc gtcaattctt cccaccatat gatgctgctc cagttgtaga caacaagata
     3841 ttagctgata cgcctcattt aaaagaagcc ttaaataagt taggtcatac catcagtacg
     3901 gaaaaaatgc aggaattgaa ctacgaagca gataataatc tagtggaacc atcagtagta
     3961 gcacaacgtt tcttacaaga aaaccactat tttgaaggga agtgaagcaa ttggataaaa
     4021 tgaatgtctt tcaacaattt ttctattatt tccaggaaaa tggctcctat atctttgcac
     4081 aatttatccg tcacttcctg atttctatct atggtgtcct ctttgcagca gttgtcggga
     4141 ttccggttgg gatcatgatt tctaggagac gtaaattagc aaactgggtg attcgtttgg
     4201 cgaatatcat ccagacgatc ccttctctag ccatgatctc cattttaatc attggattag
     4261 gcctgggagt caatgtcgtg attgttactg tatttttgta ttccctctta ccgatcatca
     4321 agaatacgta taccgggatg atccaagtag acaaaaacat ccttgatgtc ggcaaaggca
     4381 tggggatgac tgctagacaa cgactattca tggtagagtt accactctct gtttctgtta
     4441 tcatggcagg cataagaaac gcgttagttg ttgccatcgg gataaccgcg atcggtgcat
     4501 tcgtcggtgc tggtggtctt ggagatatca ttatccgagg aaccaatgca acagagggca
     4561 catcgattat tttagcaggt gcattgccaa ctgcattaat ggcgatcatc acggactggc
     4621 ttttaggtat tttggaaaga cggctagatc cagccagccg tacatcacgc tgatgttatt
     4681 gtaaaaaaca aaagcttctg cgaccatttg ttggtcgcaa aggctttttt agttctgtca
     4741 tttttaaggc aataatccac tctgattctt ccctccttat gggcaaagag ttgcttttct
     4801 tagctattta tccattccgt atactccaac ttcatactgc caacgggttc atatctgcat
     4861 ccaccgacta agtttttttc ttatccgcta aggcattttg ccaatccatt ttcccatcac
     4921 tcgtcatgga attcatacca catgatctct aaatactcgt ctgcttgttc tttgaattgg
     4981 gcatcaattc ttacatcctt tggcgtggct ttcatttaag ccttttccat cagtcctcga
     5041 ttgttcgatg ccttcagctg catcatcaaa actggtgact gccgtatcgg taacttcgat
     5101 catcttttat acaatcggga acttgccatc ctcatccttg gctaaaaaca tatctagcca
     5161 ttccagcttc tcgccatggg aggtttgcgg ttcctaaaac cggtacacga ttcttatgga
     5221 ctgcatccgt cgcaactaga cttggcgata cgatgatcct tcaccagaag agcacccccg
     5281 taaaccaatt gatcgatata ttgccaataa gaaaagacat tggcgtaaaa gatatcgatc
     5341 cctcgtgatg cattgccgtt gatactgcta ttcatggccg aaagcgccac gactttaact
     5401 tcttccgttt gagtgacatt catgttcggc aatgtcgctt tggatacccg ctctgctaaa
     5461 ggaacgacac tggtattgta tttcgtatct gtatcttttc caaaagacca tgccaacgaa
     5521 tcctctggga accaataaga cgactccggt tgattgtcca ttgctttttt caacatactt
     5581 ttggctgttt ctcgataaac gacatttcca attgtcttcg cctcactttg gcgataatcg
     5641 atggtcgttg ccactgccaa cactaacaac gatgctccaa ttttactgat tttccttgtc
     5701 acacttcttc ctccttgttt tacataaacc cgtcaacatt ccattcctaa actcaaacaa
     5761 tgacccttca aaggtggaga tataggaaca aattaaagaa atcatgcaat aaatccaaga
     5821 aggttggttt tagaacaaaa aaagagtctc ctttttgggg agactctttg ttaactatct
     5881 aaaaaggttg gctcttctca cttcactcat aatgtgtcca ggcagaataa atttctacaa
     5941 ctttattttc ctcatcaact ttgtaaacca ctcgatgctg tctattcagc ctgcgtgagt
     6001 atctgccttc atgtgtaggt ctcagctttt caaaagactg cgtgggcata tatggatctt
     6061 ccttcaatgt ctgaatcact tcttcaaatt gtttctttaa attcgtttgc ttgatttttc
     6121 ttaaatccac tttcgcagag tttttgattg cgactgtata gttactcatc aaagagcttc
     6181 ccaatcaata tcatcgatat tcgtaaagct actgtcgtct ttttcgcggt ctcgtacttt
     6241 atctaaagta cctgtttgct caagaaaaag ggtttcttga atcgctctcc agtcttccag
     6301 cccaatcaat acagcattgt ttccactacg atcactaata atctcgattt cagtatgatt
     6361 ttcatttacc tctttcaata actgataaaa atttttacga gcagtgctag gattcatcgt
     6421 tgtattagcc attgtctctc ctcctttttc tgatataatt atagcgtact tgattaagta
     6481 cgtcaaaaaa atacaataaa gcacttaaat tcagcaaact tttcctcttt tttacataga
     6541 gaaaaagacc cctttttagg gaggatcttt gtccacgctc acttcttact cctttacgac
     6601 tagcggtagc caaacgtaaa gtaattggta acaacgtatc atctttagca aaggtcgaat
     6661 ccaaagcctg tgagtctatg caacaacacc aatacacgaa ggttcctcgt tgcagtgtga
     6721 cttgattgat atcttgaata acctgaggat acgcacgaaa gatttgtaac ggttattcaa
     6781 aactgatttt ggccgtcaag tcttctactg cctcaaaaat gattgcctct ttcgtctcct
     6841 gtcattcatg ttcactatcg atttgatact tgcttagacc gttgggtttg tgaatcacca
     6901 attaaaaatg gcactgagtt atggtaacaa aaaatggtca cttgacgagg ctgagattcc
     6961 tacttatgaa gacacatggc acttaagagt cgaggtaaag gaagaagctg aaaatatagg
     7021 aggctgtaca ttatttggca aaggattcgg aaattatgat caagacatca aaatcaaaat
     7081 gttttacagc taaataggaa gaataataac atttcatacg ctgttcccat ctttaatggc
     7141 ttatagaggg cacctttagc tgagaataag acaaaacaga ccctctagct tcaattaaga
     7201 gctagagggt ctgtttttga ttttaaaact tggtttattt cttcaaatgg tagctatagg
     7261 tgctgacaac gatattttca cgccaagaca atcgcaatct taaccgcaaa cttgtttggt
     7321 tatggagaat attctgccag cgtctgtttg gtacaaattg aggaatcaac acagtagttg
     7381 tatagttttg tttcgctgca tttttactta cgatatctac ataacggata attggatttt
     7441 caatcgagcg ataagaagag tggacgattg aaaaacggac atctgggaaa tgctttttaa
     7501 attctgcttc gatttctttt tctttttcga catcttcgtc tagcgaaaca tgcatcgcaa
     7561 cgacataatc accgatcgaa cgtgcgtaat tcaacgcacc gatatttacc cgtgtcacat
     7621 tcccgactaa tacaagaacg gtattcccgt cataatcatg tagttttgca tcattttcta
     7681 aacgaagctg ttctgctact tttttataat gatcatggat cttataaaaa atgaacataa
     7741 cgattggcat aatgatgaag aaaggccaaa tgtcccctaa ccgatagaca aacaaaatcg
     7801 caatgattgc atatgagatg aacgcacccg taatattggc aatcgatttg cttaaccatc
     7861 tttttccttc ttttttccat ttgacgacca tccctgtttg agataaagca aatggaatga
     7921 acacgccgat agagtataac ggaatcaagc gttctgttga gccatggaaa ataaacagca
     7981 atacgatcga acctagcgct agtgtgataa tcccattgga atagcctagt cgatccccac
     8041 gatcttgata catgtgaggc atgaatttat cttttgccag attgtatgca agaactggaa
     8101 aagcagaaaa accggtgtta gcagcaactg ctaaaatcag cgctgtagca aattgaagga
     8161 cgtaatacaa aataccatgt ccaaagacag ctttaccaat ttgagacaaa acagtgactt
     8221 ctttttcagg aacgatccca taccaatagt tgataaatgt gatccccacg aagaagaaac
     8281 ctaagatcaa tgccatcatc gtcaatgtag cagcggcatt ttttgctctt ggcttcttaa
     8341 agaatggtac agcattacta atcgcctcca ccccagttaa agaggaagaa ccagaagaaa
     8401 atgctcgtaa aatcaaagcg atagaaacac ccggcacagc cgctcctgga agtgcagtag
     8461 cttgcaatgg cacagcacct gtcacgatat tatataaacc aacaacgatc agtaacgaga
     8521 tcacaaggat aaatgtgtac accggaaata ataggaacga tgcagattcc ctcagcccac
     8581 gaagattcag catcatcagt agcaaaacga ttgtcacaga aatagcgact tgatgaccgt
     8641 agagtgctgg caccgctgat gtgatcgctt cagcacctgc tgagacagat actgctactg
     8701 tcaacatgta gtcgatcaat aaagagccac cggaaatcaa gccagcattc tttccaagat
     8761 tctcactgct gacgacatat gctcccccgc catgaggata agcatggatg atttgacgat
     8821 atgatagcgt taatgaaatc aataaaataa taacaaaagc ggcaatgggt agcgaatacc
     8881 agatggctgc agcagacaaa gcgactaaaa cgacaacgat ttgttccgta ccatatgcaa
     8941 tagatgataa cgcatcagac gacaataatg ccaaagcagc aaatcgggtt aatttgtgct
     9001 catcattttc agcagatttt aaaggcttac ctactaacaa cctttttaag taatccaatt
     9061 tctaaactcc tttacacaca attttacttc aagttttata gtcgaaaatt tatagtaaac
     9121 aagatgttat agtacgctca ctgaccttaa aagtcaataa actttaagaa aataattgga
     9181 aaaaaacaga aaaatatcaa gcgctttttc aaacgcttta atacagcaaa aatctaacat
     9241 ttttttatgg gctttttctt tgaattctat aataaaagga tagaacttga cttagaaaat
     9301 caagttctat cctttttgat atcttaactt ttggaagaga gatgtaaggc tgctttctac
     9361 ccatcattct tactactcga agcatagcgc agttgtcaca acctcttgat aaacggtgtt
     9421 taaaagcttg catctgcggt aataagccca accaaattaa aaacataaga agctgttttt
     9481 atttggtcgt tcttattact tgatgcagag cagctttttt acaacctctt ggtacacggt
     9541 gttcaatcag ctgaccctcg gtattagctc aaaaaaacgg caaaatatga ggaactattt
     9601 ttccattttt ttctctaata ctcaggtcaa aacactgatt tcacaacctc tttttttaat
     9661 gaaaaatatg gctctcatgc gccgcttctt tgaatttcgt cattttttct tcgatgaacg
     9721 gatagattgc cgttcctacg attccaaaga caacaaacaa accgatcatg atccagattg
     9781 ctttcgtagc atttggccaa taaattcctc ctgcagattc ccgtaacaag tttaccgcat
     9841 gagtaaatgg caagaacgga ttgatcattt ggaagaattt ccctgagact tggatcggat
     9901 agttcccgcc tccgccagag atcgacagta ctaagatgat aatagcgatc cctttaccga
     9961 cattatcgaa taatgcagcc aagacataga cgatcatcat gaacgctaag gcgatcaaga
    10021 cagcaaatga cacgctgtag accggatttt ggacatctac tcctagtaag aaaatattcc
    10081 ctaatgtaac gatcaagctt tgcgcaatcg ccattgtcaa aaatgtcagc atacgagcaa
    10141 cgaattgttc tcgtttcgta aaattgtttc ggtctttctt tcctaaatag tattctgtcg
    10201 tagcaacact tgaaagaaga acagcgccga cccacagaca tagtgcagta taaaacgggg
    10261 tgctagctga accgttattt gcgattggat aaagcgcatt ggtttgtagc tcaacaggtt
    10321 gtgtaaagaa gtcactttct tttgttgcgt ctagtttcaa taatttgatg acttcgccta
    10381 gatcgacttc ttgttcgcct tttcggatcg cgtctgctgc tttttggata ccagctttga
    10441 tatttggcca gtcattgttg atcaagtccg cagcagcgtt cacagctgtt tcgacttctg
    10501 gcattttttc atttactgtt gtcaatgtac cggtgatttc attttttagt gctggccaat
    10561 cattttggat aaaatcagcg gccaatccta atttttgctg aatgatcggt aattcattgt
    10621 tgtataggtc tgccccttca ttgatgccat tgacgatggt atccatattt ccattcagca
    10681 ttgtattggc atcatggatt tcttgtccaa ttgcaggcat ttctttttga tatttttcta
    10741 aaattgccac tgcattcgtt acagttgctt tcgttgagct gagaagcgaa tcaaagtcga
    10801 tctggtccgc tttgctcagt gcgccttgtg cagtcccaat cgtatcgatg acttggtcta
    10861 gtagagaagt gacagtggaa ctgatttgac ctgtattgat accagcaatg atgccattga
    10921 tattattaac aacggcatca atttgatcta gcaattcatc aatagccttc gtgtcttcat
    10981 tttgaacagc tgtgttcaaa gcagataggc ggttttgcag attgcttagc aagggtttta
    11041 attgatttag ctgatcaata attggctgta atttcgtatt tccagcactt gtttgcaatt
    11101 tagtcaggaa ctcgaccagt ttatcgattg cattttgttg ttgagatatt ccgtcaataa
    11161 agccgttcaa tacattgctg atgtttttct tttcatcatc agtcagctta ccatcttcaa
    11221 tagctgttct tacagtatct attaacgaac ctgtcgttgt tgccacttgt ccaattgact
    11281 tcaatgtaac atctacactg tttgtgatgc ttggtatcgc atctttcagc tgagaggcac
    11341 ctgattttgt ttggtttgct agatcacttg cctgattttc taaatttttc acatctggca
    11401 agatatcttg tacttgttgg atgatcgtca agccttgttt tgcttcatcg attccttggt
    11461 tcattgtctc ttggatcgaa gcaaaatcgc cgtcgatctc tgctagttgc ttaccggcat
    11521 tttggatctc tgggattttt tcttgcaaat caaggatgat ttttgcttga tctttcaact
    11581 caggcatttt gtcattcaat gcaacgactt tttcacccat ctcatctact ttagggatgt
    11641 aatccacgaa ttcatttgct ttattcagtt tttccttgat ttcaggtagt tgactttgta
    11701 attcgaggac ttgttttgtg tagccgtcga tcgtgtccaa attttcatct gttgataaaa
    11761 tcatatcttt aactttattg atacttacta ggttcgtatc gatgtcgtaa cctatctcat
    11821 tgaatacttt caataaagtc gaactggctg ttttgataaa ttcatttgtg atttgcgatt
    11881 ggatcgaact tgctccttta tcggtgattt tcggtgcaat cgcattgatt ttttcattta
    11941 ccgtatattc gatttttggt ttcttgatat caccactagt aaaactcagc agatcttctg
    12001 agaaatcctt tggcaagtaa atacctgcgt aatactttcc ggaacggact ccgtcttcta
    12061 attgttcttt tgaatcaacg aattgccatc ctaattgttt atttttatga agcgattcga
    12121 tgacttgctc cccaatggcc acttctttac cttgaaactc tgctggcttg tctgcactgt
    12181 aaacagcaat tggcagctct ccagtatttc catatggatc ccataatgct ttgatgttaa
    12241 accacgcata tagcgaaggg atgatcatga tcgcgatgat cagaagtgtt gcaatcgggt
    12301 ttttgaaaat ccgtttccag tcaagcaaat ataatcgaag cgtatttttg attgactgca
    12361 tagttctccc ccttcttctt ttttcagctg aattacttta ccatgtattt catacttttt
    12421 tcaatcggct tttttcaaaa aagtcgaatt tttggacata tcacggcaat tgtctcattg
    12481 taatctctta catattgaga aataattaag gattacagcc tttactttat catgaaataa
    12541 aagggaaaga taattttatg ccaaagtttt tatctattat acgtatacgc aaaaaagcta
    12601 aaacattttt tgtctttgcc cctacaaaaa tgtttcagct tttttcgttt tttattcctg
    12661 tatttcttat ttttcgaatg acaggatgat tttcccagca ggaggatgtc cttcaactag
    12721 ctgatgtgct tggatgacat gcttaagtga agcagacaga ttcattgaaa taaaaacatg
    12781 aaaggctcct ttttggtagg ctttgattat gccagcaaag gcttctgcat ctagatattc
    12841 ctttcttgga acaaacgatt cataaaagcc ttcctttttt tgccgcaaat ctagatctgg
    12901 gaggtcattt aatgcaacat acctgccgcc tggtttcatg atctggatgc cggtttctcc
    12961 tttgatactt cctttcgtcg catcgattac aaggtctgcc tgatcagcaa attgcagacc
    13021 tggatttgtt ttatcataag cagcaaatgc tgaagctcct aattttttta ccttttcctc
    13081 atttttactg gatgcactgg ttaagattcg gattcccttt tcatggagaa gctggatcag
    13141 acttgacccg accgcacctg atgctcctag tatcattaca gtatctgtcg gctggatttc
    13201 cgtcaaatgg ttgattagat tataagccgt aattcctggc gtgaccattc cggctgcttc
    13261 ttcccaactc attttatctg gaatttttgc tacttttgct gatggcaaca cgacttcttc
    13321 tccgtaagtc ccgccgactg catggacagc tactcgatca cctacatgaa cagttgtgac
    13381 atctgaacca atctctgtca caataccagc gccatcatta cctggtacat aagggaattt
    13441 caatgttcgt atctctttca tttctcctaa acgcaaggca acatcataag gattcacact
    13501 gaatgctttt atttctacac gaacatgtcc agaaccgact tctctgggat gagcatcgat
    13561 ttcttcaaaa acatcttgtg cttctccgta accgttaatt gcaaatcttc gcatggtcac
    13621 catctccctt tttctttaag tttacgttta tgcctttatt ttgacaaaaa aaatgtcttt
    13681 tcgttttggc gcatgattca aaacaaaata gttgtctttt ttcgcgtaac gtgttaaatt
    13741 atttatctaa aagcgtaaag attacgattt acgctaataa aaaataattg gaggaatttg
    13801 ttgatggcta aaaaatcaaa gattgccaaa gcaaaaaaac agcaagaaac gattgaacgc
    13861 tatgctgctt tacgccagga attaaaagcg caaaaagatt acgaaggctt gcgtaaactt
    13921 cctttagatg ctcgtccaga acgattgaaa aatcgtgatt taatcgatgg acgccctcgc
    13981 ggatacatgc gtaaattcgg gatgtcccgt ataaaattcc gtgaattagc acataaaggt
    14041 ttgattccag gagtaaaaaa agccagctgg taatccaagt ctggctgtaa tgtaaaggag
    14101 gagggcgcat ggaccactcc ttggatcatc aaaaaagata cgttcgcttc ttctagcaga
    14161 aatgctggta ctagaagcag acgtatcttt ttttacgcac agctggtcct tttttatatg
    14221 taaaggctgc atggttactt cgctatattt atttagtaac aggagtcagt gcttcgatac
    14281 ccacactaat tttcaatgct cggtcaactt ctgccataat gggtcgatcc aaatggcaga
    14341 ccttttcttt caatcttgat ttatcgatcg ttctgatctg ctccaacagg ataacggagt
    14401 ctctttctat tcctgttcca gtagctttga tcccaatgtg agtcggaagc ttaggtttag
    14461 ccatttttgc cgttatggcc gcaacaatga tcgtcgggct aaaatggtta cctagattat
    14521 tttgaataac caaaactggg cgtgttccgc cttgctccga tcccacgact ggagaaagat
    14581 cagcaaaata aatatctcct ctttttacca taggatcctc cttattcttg atattctctt
    14641 ggtatccgct gtcctaatcc gcaagccact tcatagtgga tcgtacctaa ttgatctgct
    14701 atatcctgca tagtgatttc tttgtctgca tttttgccga taagcgtcac ttttgttccg
    14761 acaggaaatt cttgaggcaa tcggatcatc agttgatcca tacatacacg cccaatcgtt
    14821 tcacagtagt tcccttctac caatagagaa aaaccctgca tctttcgtgg ccagccatct
    14881 gcataaccga tcggtatcgt tccgatccac tctgcttcag gagtgatata tgtttctcca
    14941 tagccgattc cttcacctgc tgggagtttt ttgacttgaa tcaattcaga aaccagctca
    15001 agtgctggct gcaatggata aacttccggt agtgcgtgcc cagagggatt aagtccgtac
    15061 attgctactc cataacgaat catattgccg attgtttcat catgccataa agccgttgca
    15121 ctattgctga catgtacata tcgaggaagt tcgggaagtt ttttcagcac ttctataaag
    15181 cgttcttttt gcagattcca atatgtatca tctgcctgat ctgctgtaga aaaatgggta
    15241 aataaacctt cccattctaa tacacgactt tctttgatga atgcagctgc ctcttttact
    15301 tcttcaggtg tacaaaatcc gatacgaccc atcccagtgt ctgcttttag atgaatcgaa
    15361 agaggcgtct ctagcttact tttctctaaa acagcagctg ctgcttgcaa ccattcccgt
    15421 gtacctgcag ttactgataa atcatgagca acagctacag tcagtgcgtc gtaaggaacc
    15481 atattcaaga taaggatggg ctgagtaaat ccagcttctc tcaactcgac tccttcatct
    15541 aaatttgaaa cacaaaagcc cgaagctcca cctgcaactg ctgcctcagc tgtttcaata
    15601 gctccatgac cgtatccgtt cgcttttact actgcaaaca attcttttcc ttgcggaagt
    15661 cttgcaactt catttgctac attttcagtt atagcttttt tatgtatcac tgctttcgtt
    15721 gggcggtgcc aagcgacaac catcgttttt ccttctttct agtcttccaa aataatttgt
    15781 gcaaaagctg tttcatttgt atgagtaata ctgacccata cattgccttc atgaggtgaa
    15841 cgcgtcacaa caggctgacc attttcattt tttaaaatct cgacatcttg aaaggtaact
    15901 tttccgatcc cagttcccca agctttagag aaagcctctt tgcaagcgta acgcccgcct
    15961 aaaaattcta cttggcgatg aaaaggcaag gactggaata gtttcatttc atcagaggtc
    16021 aagattcgtg caatgaattt tggtttttct tcgatcagcc gagtgatcct aggaagttcg
    16081 actgcatcga tcccaattcc ttttatcata tgcttttctc ttttcaataa atttagaaca
    16141 ctctcattct accaaattat aaccattttg ccacaaataa gtccacaaat aacaaaaatg
    16201 aaagtttctc ttaaaaaaga gaaactttca ttttatgttt aatcgttatt tgaacggatt
    16261 acaaatccgc gttttttatc attgtgacgt ttaccgccat ctttttggct gttattattt
    16321 ttgctataac cgccttttga tttgtttcca cgataattac cgccgtcacg acgattacgg
    16381 ttgtttccgc caccacgttt gccattttta ttgtatcctt ttttctgcat tggcaatggg
    16441 cgttctggtg tgatcttcac tggcactgca tcagctggat cttttgctgt cgtttttagc
    16501 aaaagtgcaa ctaaatcttg tgcagaatat tcttctaata atttatctgc tgtttgcagg
    16561 tatttatcta gaccattttc tgcaagtttt gtttcgattt gttcaactgc agcacctaat
    16621 tgacctttga atgcttcttt ttcggttggt ggacgtaaag tcgtcatccg ttttttcgtc
    16681 aagttttcaa tcacatgcaa gtagtccatt tcatttggtg taacgaaagt cacagacata
    16741 ccgccttttc cggcacggcc tgtacgtccg atacggtgaa cgtagctttc tggatcttga
    16801 gggatatcat agttgtacac atgagtgaca cctgaaatat ctaatccacg tgcagcaacg
    16861 tctgtcgcta caaggatatc taaatgaccg ctcttaaatg aacgcaatac gctcattcgt
    16921 ttttgttgag acaaatcgcc atggattcct tctgcacggt aaccgcgtgc ttctaatccg
    16981 cgtgccaatt cgtctacacg gcgttttgta cgtccgaaga cgattgttaa ttcaggtgtt
    17041 tgaacatcaa acaagcgagt catgatatcg aatttttcgt attcttttgc gcggacatag
    17101 tattgatcga tcaagtcagc tgtcatttct ttcgctttga tcttcacatg atgtggattt
    17161 ttcatgaatt taacgccaat attcttgata gctggcggca tcgttgctga gaaaagtaat
    17221 gtttgtcttt gatcaggaac ttgtgaaatg attttttcga tatcttccaa gaagcccata
    17281 ttcaacattt catctgcttc atccaaaact aatgtttgaa cggttccaag tttcaatgtg
    17341 tggcggttaa tgtggtcaag catacgtcct ggtgtaccca caacgatatg tggacgatct
    17401 ttcaagccac ggatctgacg gccaatatct gctccgccgt aaacggcttg tacacgtact
    17461 tttttgtcgc gccctaaacg atataattct tcttgtgttt ggatagctaa ttcacgtgtt
    17521 ggtgcgataa ctaaaccttg taattcgtga cgatctggat cgattttttc taacattggt
    17581 aatccaaatg cagctgtttt ccctgtacct gtctgtgctt gtccaataac gtcttttcca
    17641 gctaatgcta gtggaatcgt ttctgcttgg ataggcgttg cttcttcaaa accagcgcgt
    17701 tcgactgatt tcaacaattc tggtgataat tctagttctt taaatttcaa atgaatcctc
    17761 ctatatggtt gttaactgag gatgtagctt ttttgctacc ccgtcgattt gttcggtcaa
    17821 agtgtattgt ttctttttga cagtggccac gcacgttttt atccattctt agcccctgtg
    17881 gcaccaccga aaaatcactt tgcgaagttt aggcattaga aaagccaaac gggtcgcgtt
    17941 cagctttatc attattatga catctggctt caacaagttg tttctatggc aaaaccagtc
    18001 caatttctct tcatctttcg gcaataggtt attctaacat agtttttcgt tttctgcaag
    18061 tttacagatt tttatttcat ttgctgaagt tgttctacca cttcaaataa gcccatgctg
    18121 ttgctgcctt ttagcataat actatctgtt gcttcaagat tttgtttgat agcatcaatc
    18181 aatttattct tttctttttc aaaatagaac acaggtagtt gggggtattt ttggttcaat
    18241 tcttctttta gtgcatgcat ttgttcccca taaaggaaaa tcatggcgaa tttctcagga
    18301 tcgatatgtt cactcatttg cgcatgcata tttaaagact ctttccctaa ttccagcata
    18361 tctgctaaca cagcgattct gcgtcctttt gttggcagat ttttaaaagt atctaatacc
    18421 agtcccatgg ctgttggatt tgcattgtag acatcgctca aaatagctgc accatttcct
    18481 gccgttagcc attcggttct gttttgagtg atagaaacat gggcgagccc ttggcgtatc
    18541 tcaggtatgg acagtccaaa gaagcgcccg atcgtatacg caatcaaagc attcgttaca
    18601 ttataacttc caggcagcgg gatcgtaaat gtttctcctt ctactacaaa atcggtttgt
    18661 gcttttcctt ttgctgtcac ttccgcatga acatcgccat ttccaatacc gaatgttgtg
    18721 actgtttgta ctaatgttgc cgttaaaggt gtcagcaacg gttcatctgc gggcacaacg
    18781 agtaatccgt ctgatacaag tccgtcagtg atttccattt tggctttagc gattccttct
    18841 cgcgacccaa gattttctat gtgtgcttca ccgatcattg tgattgctgc agcttttggt
    18901 tgagccataa gtgaaagttc cgtgatttca ttggcgtgat ccatgcccat ttccaaaacg
    18961 atcttttctg tatcttgggg catgtgcaaa atcgtgtaag gaagaccaat attattgttg
    19021 taatttcctt gcgtcttata tgttttgtat ttttcagaca agacagacgc ggttagatct
    19081 ttcgtggtgg ttttaccatt gcttcctgta attgcaacga cttctgcgcc tactttttcc
    19141 aagtaatagg ttgccaattg ctgcatggct ttcaaaggat ctgctacagg aataactgga
    19201 aaattttttg gagcttgttc aacaggcaag ctccaaaatg aagcagatgc tccgtttgtg
    19261 atcgcttgct ggataaattc atgtccatct cgcgtaccag caagaggaac gaataaactt
    19321 ccttcggtta tcttccggct gtcaaattcg acattggtaa tctttgtcag tgcagagcat
    19381 tcgctgccca cggcttgtgc aatttcttgt attgttagat tcattgagat ctctcctaaa
    19441 aaaggttgtg aaaaaagcgt ttggcctaaa cggcgggttc gcatgactct cacttccaag
    19501 taaatttctc tattcgtatt tagaagctag aatgaacgcg gttacgcaat cactccagcc
    19561 tcttctttat ttctctttat tcattttttt caaaaaaaga ttgacgctga tggtatcgat
    19621 tcattcctaa ctggatcagt tcttcaatca aatcaccgta tttcaagccc atattttccc
    19681 ataagagtgg gtacatactg aactccgtaa atcctggcat agagtttaat tcattcagga
    19741 ataattcatt tttatttgtc aaaaagaaat cgcaccggct caatccgctt ccacctaaca
    19801 tcgtgtaagc taacttcgcg tactcttgcg ctttttgata aacttcttct ggcacttcgg
    19861 ctggaatctg catttcgatt ttattattga tatattttgc ttcataatca tagaatgcta
    19921 cgtcttttac gacttcacca ggcaaagtcg tccgaacgtc ttcatttcct aatacagcaa
    19981 cttcgatttc gcgcgcttca attccttgtt caacgattgc tcgagaatca tactgatagg
    20041 ctgttgctaa agcattttgc agctcttctc ggttttctgc ttttgtaatg ccgacactag
    20101 aacccatatt cgccggtttg acaaacatcg gataaagcaa agaaccttca cattgatcaa
    20161 atactttttt aggattttct ttccattgat tcttaagtac tggtacataa ggaacttgcg
    20221 gcacaccagc agcttgtaaa atatacttgg tcatgatttt atccatggca catgcactgg
    20281 tcaatacgcc tgcgccgaca taaggcatat tcaatgtctc taagaagcct tggatcgttc
    20341 catcttcacc gttttgccca tgtaaaactg gaaaaacgat ggctccttct tctttgattt
    20401 cgcccggatt gatcactttt cctgtaaagc cttcctctgt ctgtccactt gggtcccatg
    20461 aaagatgcaa gacatctttg ctggcaggtt tttctgttag taatggacct ttgacccatt
    20521 gtccttcttt tgtaataaat acgagttgaa cttggtaata attataataa atggcattta
    20581 aaactgaaaa tgcggaaaga atggacactt catgctctgc gctgcgtccg ccatatagta
    20641 aagtaatctt caaaagattg tcctcctgta ttctaaatcg ttcagtgatt tactctcata
    20701 ttttagcaca aaacaaaaat aaacgaataa cttatttata aaaaaacgag ccagcttcta
    20761 aaagaacgag cgtcatttat tttttgtcag ctagattatt tgtcccgttt tttataaaaa
    20821 gttatgataa agaaaaggag ggatgatgat ggcgcaaaca aatccacgca gccgcttggc
    20881 agaaatcatt cgagtgttca tcaattacaa tgtagtgcca aactttgtac agcaaaaaaa
    20941 tcccgaacag gtaaaaaaag cctttgaaga actaggcccc accttcatca agataggaca
    21001 gatgctttct gttcgagaag atttgctttc ttctgccttc actcaaacat tcaaaacatt
    21061 acaagatagt gtacctagcg acacattttc aacggtcaaa aagacgatcg aaacagaact
    21121 ttctctttca ttatcagata tattcgatga tttttcaaaa tcgccttttg cctctgcttc
    21181 tatggggcag gctcatcgtg ccaagctgaa gaacggtgac gcggtagtcg ttaagatcca
    21241 acaccctaac atcgccgaag agatccgact tgatcttcaa ctatttgaac gagcgatccc
    21301 tttgatcaaa tacattcctg aaactagcgt agttgatcta aaaggggtac tccaagaagt
    21361 aaaacgttcc ttgatcaatg aaatggactt cttaaaagaa agtcaaaatg gcgaacaatt
    21421 ctatcaaaag aacaatggct ggaaagagat ccgcagcccc aagatttatg acgctttttg
    21481 ttcgaaaaaa gtgatcgtga tggaagaaat gtctggtaaa aacttgaatc atttaatgaa
    21541 cgccgaaaac aaaactgaaa cttttatcac tggaattcaa aacaagcagc tgaaacaaga
    21601 agttgcaaag cttttagttg agaactttat gaaacaggtg tttgatgatg gttttttcca
    21661 tgctgatcct catccaggga atctgctatt ccatgtacta acaaaagaag aacagacaca
    21721 agctagccga aaaactgaaa cagtccatga aaaagagttc ggttcctttg cttttcgagc
    21781 ctccacttct gcagaagacc ctgttgcgcc atataccatc aactacatcg attttggtat
    21841 gatggggcat ctttctgcag gacttaggca aaaactcaca caagccgttt tagcgctgta
    21901 tacgaaagat gcttatcgaa tcgaaaaagc ggtccttcga ctttgtcagc aagaaggctc
    21961 gtttgatgaa agtcggttcc accaagaact gacaagtttt cttgaacagt attatgattc
    22021 tcctattgat gaaatcaact tgcaagaagt attcacacat gtcgtgacga tttgtcatca
    22081 aaataatctg cagttcgatc gtgatatcac gcttttgctg aaagcatttg ggacattaga
    22141 aggggtgatc cgcgtcctcg atcctgaagt ttccctcatg gaagtcgctt cgccttttgc
    22201 tcaacattat tttctcactc atctggatgt agaagataca ttgaaacaaa gcggattaga
    22261 cttattggaa gggatgaagg ctgcgcctaa gatccctcaa cagctccacc atctattaga
    22321 aatgtggact tcgggacaag gaaaagtcaa tttggaattg aaaaagcaag acaaattatt
    22381 gagcaggatc gaaagtatga tcaatcggct tgttttcggt atgattttag ctgcattgat
    22441 cgtagggtcc tccctgcttg tccaagcagc acctgtagaa aacgcagagg tcgtttcctt
    22501 attagggata tttacgtatg ctattgccgc attcgtcatt atttttttgg caatcgatgc
    22561 attgatccaa atgtataaga agaggaaaaa gtagaaaaag gttgtgacag aaagaatcag
    22621 cttcaagaaa taagaagggg ttttacataa attgtttctc aaatttttgt gaaaattcgg
    22681 cttatttttc gaagaggcta cttctgaaac accgagaata aaaaatgtga aaaagctgtt
    22741 ctgcacccag taataagaac aatcaaaaag ggaacatgga acacatttat cctgtttccc
    22801 tgttcccttt ttgatgtatt cgagcataaa taaaatacct tcgttaccta ctatcttctg
    22861 tacttggtaa accttagtca attgcctttt ttaacgcttg acgaaaagac atatgatctt
    22921 tctccgtaaa gggttttgga ccctttgtcc ttatgccagc ttttcttaac tttccactat
    22981 gataacgttg ttctagaagc gtgccgatat tcgcttcgtc aaattctttt ccagagtgat
    23041 ggaacactcg cacacccttc ggcaatacaa gtgaagctaa accataatct tgcgtgatca
    23101 aaaagtcatt cttcttaacc ataccgacga ttttataatc cgcactatca gctccgcggt
    23161 ctacgtagac gatttggaca tgattagcgt attctttggt cgtataatgg tccacactgg
    23221 tcacgataac cacgtcaaga ccataggatt ctcctaattt tatgacatct tcttttactg
    23281 gagaaccatc tccatcaatg aatagcctca ttctttttcg ccttcttcca taaatgataa
    23341 acagttacta atccgctcag taaaagacca acattgatcc attttgccaa gataagcagt
    23401 tgtacacttt ctatcggcac tgattcatgg ttcagcgtga tcaataatag atggattggc
    23461 tctcccattt cttttgctaa aacaaacaaa agcgtcatca ataaaaactg gtggatcaca
    23521 ctccctttat tttgagtagt atacttgaca acgatccggc gatccattgg aatagctgta
    23581 tcagtttgat aatattcctt atttagccag ctgcctgtta ctacgtgcca gaaactaagc
    23641 agaaagacac ctatcgcaaa accatttgga atcaagagga ccaataaaga agaactcagt
    23701 ccaagcaatt gcatagccaa tggagaccat gttaaacgtt tcaaaatcca tggtccgact
    23761 atttttgctg caatcaagcc tgctgcataa ggcaaataca taaaaatcga aagtttttct
    23821 aatccgtaca gtatgccaac ataaaaactg ctaaataaaa aaaggaaatt ccctagcatt
    23881 ccatttagaa aagtaaacag atttagccag cttggcaact tccattcctt cttctggtgt
    23941 cctaaaacaa acacgaacaa gatgaacagc agcaagaaac cataaatagc aagatcaaaa
    24001 agcctttcat cgaataacaa tcgggcattt ctcaaaagaa acaataagcc aaagaatatc
    24061 aaaaataaaa caagctctcg cgtagctacc agatttcttt tgatgtcttt gaaatccagt
    24121 tcgtaacgcg gataatgact aaccgtatgg taggccatga cgtaaaaaag tgtataaata
    24181 gtaaagcttg ctgcaatctg agtcggtgca ggcaactcaa tcgcttgata caggagaaat
    24241 agccagatag ctgcaaataa gtactttttc ccatccatat tgataaaacc ttgcgtcttt
    24301 tcgtgaaaat tgaccgtggt attagcaggt acaagccatg ctgcactcag ccctagcaaa
    24361 acacttgaaa aataaaataa aggaaaataa aatacgccta atattccaag caatgaacca
    24421 gcaccaccaa tcagcagagc gatcatcagc aacgtgtaac tatctagacc aaatcgtaga
    24481 ctgttgacta aaaatagtcc agtcatccga aaggcataaa acagcgtaaa tggcaaaatc
    24541 gtcagccaat tatgcgagtc tgttagtccc aaaaataaaa gataaggaat aaaaataacc
    24601 gtgttactta agataaaggg cgttgtttgt gtaaaattac gcccaaatcg tttgagtttt
    24661 tcgaacatga caatggctcc ttaaacagtc ttataactaa tctgctcttc gattttagca
    24721 ttaaagggga aataaaccaa ttttacagaa tatattcttg taaaaaaaaa tacagaaaga
    24781 agcataagct tctttctgca tttttacggt acttgattac tcaagcagac aagcccttct
    24841 ccacaaaagt cttgcccgac acccctgcat ccggcaggtg ataaagatag aaatcaatta
    24901 tcctgtgcct ccaaaatcaa ttaggagctc tgtaaaccag agtccttctc gacccgtcgc
    24961 ataaatttac tttaacacag ttcctatgtt tatgcgagag cttttttcat tttataatcg
    25021 accatttgaa atccttgacc gatatctgaa ataagttctt ctgtaatctc aaatccttca
    25081 tgcttataaa cctcgattgc ttgatgattc ccctgattca ctcgcaaaaa gatctctctt
    25141 tcctttgttt gcgcagcaag ttcttcatac cagcgaaaaa ctgaagaagt caatccttga
    25201 ccacgtactt tatttagcaa atataattta cttaaataaa tttttccatt tatctcttca
    25261 taagcagtgt aaccgacagt cttttcttcg ctttttaata aaaagtagga cacaccttct
    25321 gtcagttctt tttgaatctg tttttttgac tgataagttt tcagcatgta atccacttgt
    25381 ttttgaccaa tgatcggcac aaaaacttcc ggccatactt cttgtatgac tgccatcagc
    25441 tcatccagtt cattttctgt tacttttatt ttttccatac acccacgtcc ttttttacat
    25501 tataaatgac cttgcgcttg atggaataaa aagagcatga tcatgctata cacacccacc
    25561 gaccacggtt tcaagaaaat cacaatctgc ataaattccc taaaagataa tttcgtcaaa
    25621 ccagctacta gacagatcaa gtcgtctggc gcaaagggaa gcagcaaggt aacaactagt
    25681 acttttttaa tatctttcgt ttttcttgtc agcaattcat caaatttctg atactttttt
    25741 ggcgataaaa taagctggac aaaggctacg ccatagtaac ggacaagcaa aaatccgatt
    25801 gcttccccaa tcactaggcc aatacaacta tataaaagcc caaatccatt gccaaacatc
    25861 agcatgcccg ctactgagga gatccctccc ggcaaaatag gaatgatcac ttggatcact
    25921 tgcaacagaa caaatatcat cactgcatac ttgccaaatt gctggataaa cgcttgcaaa
    25981 gacgtgctcg atcgaaaaat cccatgatga taagcataaa gaatcaacac aaagaaaaaa
    26041 aacagaccaa taatgggcat gatctgaaga catttttgta aaactgatcc ttttttagac
    26101 atctatattc cccacatctt ttttcattta ttaaaactgc ctcctt
//
LOCUS       DAFELK010000039        25787 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFELK010000039
VERSION     DAFELK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.040"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            438..992
                     /locus_tag="LP433_001894"
     CDS             438..992
                     /locus_tag="LP433_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2006043.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(1165..1638)
                     /locus_tag="LP433_001895"
     CDS             complement(1165..1638)
                     /locus_tag="LP433_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2006044.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1650..2186
                     /locus_tag="LP433_001896"
     CDS             1650..2186
                     /locus_tag="LP433_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2006045.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            2226..2597
                     /locus_tag="LP433_001897"
     CDS             2226..2597
                     /locus_tag="LP433_001897"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2006046.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2881..4152
                     /locus_tag="LP433_001898"
     CDS             2881..4152
                     /locus_tag="LP433_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL2006047.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4397..5422
                     /locus_tag="LP433_001899"
     CDS             4397..5422
                     /locus_tag="LP433_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2006048.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5716..6825
                     /locus_tag="LP433_001900"
     CDS             5716..6825
                     /locus_tag="LP433_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBL2006049.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6908..7804
                     /locus_tag="LP433_001901"
                     /pseudo
     CDS             6908..7804
                     /locus_tag="LP433_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7820..8644
                     /locus_tag="LP433_001902"
     CDS             7820..8644
                     /locus_tag="LP433_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2006050.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8676..9986
                     /locus_tag="LP433_001903"
     CDS             8676..9986
                     /locus_tag="LP433_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBL2006051.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            10134..11393
                     /locus_tag="LP433_001904"
     CDS             10134..11393
                     /locus_tag="LP433_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2006052.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11403..12275
                     /locus_tag="LP433_001905"
     CDS             11403..12275
                     /locus_tag="LP433_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2006053.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12287..13117
                     /locus_tag="LP433_001906"
     CDS             12287..13117
                     /locus_tag="LP433_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2006054.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            13157..15340
                     /locus_tag="LP433_001907"
     CDS             13157..15340
                     /locus_tag="LP433_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL2006055.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDKTVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15401..16621
                     /locus_tag="LP433_001908"
     CDS             15401..16621
                     /locus_tag="LP433_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBL2006056.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16618..18078
                     /gene="gtfA"
                     /locus_tag="LP433_001909"
     CDS             16618..18078
                     /gene="gtfA"
                     /locus_tag="LP433_001909"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBL2006057.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            18155..19261
                     /locus_tag="LP433_001910"
                     /pseudo
     CDS             18155..19261
                     /locus_tag="LP433_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19583..19792
                     /locus_tag="LP433_001911"
     CDS             19583..19792
                     /locus_tag="LP433_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBL2006058.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19785..19934
                     /locus_tag="LP433_001912"
     CDS             19785..19934
                     /locus_tag="LP433_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBL2006059.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            20088..20753
                     /locus_tag="LP433_001913"
     CDS             20088..20753
                     /locus_tag="LP433_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2006060.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(21037..22122)
                     /gene="xerS"
                     /locus_tag="LP433_001914"
     CDS             complement(21037..22122)
                     /gene="xerS"
                     /locus_tag="LP433_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBL2006061.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            22456..22689
                     /locus_tag="LP433_001915"
     CDS             22456..22689
                     /locus_tag="LP433_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBL2006062.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22686..23093
                     /locus_tag="LP433_001916"
     CDS             22686..23093
                     /locus_tag="LP433_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBL2006063.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(24230..24748)
                     /locus_tag="LP433_001917"
     CDS             complement(24230..24748)
                     /locus_tag="LP433_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBL2006064.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         8787 a         3930 c         4794 g         8276 t
ORIGIN      
        1 aattattgac gctcccgaca aaattatgat cttgcgtaaa gttataaaat attaataaaa
       61 atattttatt aatgaaaagc ttggtagcac ggttattcat atgctaattt atttcacttt
      121 atagtaaggg gagttcttag tatattgttc aaacttaaat ttcatataat ttaattatgt
      181 aaattagcta ttctaagaac ttctacggat aactgcccgt ctaaaattta aataagagct
      241 tagaatcttc atataagtaa ggttaatttt tttgtacaaa aaagtcggaa tattctgagt
      301 tactgaaatg atataaaatc ataaactaaa tcccttgatt ttattgactt tcaaaagttt
      361 atatatataa gttaatgatt atggtaaaat atatacataa tcattaactc agaatatttt
      421 taagaaggga aacaatagtg agctataatg tacaaccgtt aaggacaaat gaagagatac
      481 aagattttca gttttggcta agaagaacaa gtaatccgga aagagatagt tttttatttt
      541 tgtttggaat caataatggg ttacgtatgt cagatattat aggattaaaa gttggagata
      601 tacgaggcaa aagtaagcct attattgttg aacataaaac aggtaagcga aaaccgattt
      661 ttatagataa tttgagagaa gaaattttat tatatactga aggtaaagaa gaaaatgatt
      721 ggttatttcc gagtcggcaa caaggtcgac atataacaag ggatcgtgtc tatcagatat
      781 atgcagatat agcagaaaaa ttaggacgag atgatatagg aacacataca ttaagaaaaa
      841 cttttgggta tcactactac aagaaaacta gagacattgc taccttaatg tttattttta
      901 atcatagctc gcaagcaatt acaaaaaggt acattggtat aactgaagat gaaataggag
      961 catcacttcg tggatttaaa ctaggtgtat aatttaaaaa tttttataaa cagtaaagac
     1021 aaagattaaa agctattttt atctagaacg attttatttc ataaagttcg cggaataaaa
     1081 gctggggtta ctggtacttg gtataggttc gtgttatata aactaagtaa ttaaataaca
     1141 tttttaggtt ggaaaaggat gaaattaaaa aaagagaatc aatacggtct caaaaacgca
     1201 aacgctgcgg aataagaaaa atactgataa ctcaacgttt agcagactat ctaataggga
     1261 tagtctgctt ttttcgtttt tgaccatact tttgaccttc tgcaaacttc cttgcttttc
     1321 ctctgtagaa ctcatgaaat ctgcaaaacg aattgccgtt tcctctgtct gctttttcgc
     1381 gatatgggtg tatatatcat ccatagtggt tttaatatct gtatgtccaa gtcgaacata
     1441 cacttctttg acagacgcac cagattcaaa gagcagacta caatgggtat gacgaaaacc
     1501 atgaagtgtg atatgtttta agttattctc tttaatgatg attttcaaat tgtgatttac
     1561 atagtctaaa taaaggggct tattttcttc tgatgaaaac aaaagttgtt caccatcttt
     1621 tataggtttg attctcattt ttagatatta tgcccgcacg tattcatcac atttctattg
     1681 tgaatcgctt tattcgaccg acatttgact tttatcataa tatactcggt ttaaaattac
     1741 taatgaaaac aattaatcaa gacgatcata ccatgtatca cctgtttttt tcagataatc
     1801 accaccgtgt gggaactgaa ctgacttttt ttgaagtaca agaagggaac aaccagtttt
     1861 ttggaaccaa tacgattgaa cgaacgatac taaaagttcc ttccgaagca tcattgcatt
     1921 tttgggaaat atattttgaa acacaaggcg tttgccatta tggaatcgaa tcattttctg
     1981 gacgacctat cttacgtttt gaagggccag atgcaacacg attagcttta gttcccttac
     2041 gcgaatttga agatattgat gattatttcc cgtatgtcac agaccagatc cctacagagc
     2101 atgccatttt aggaattgat gccattcaac tacgcgtaca atattccgat gcgactgaac
     2161 gagagttatt gtcggtaggc tggtagcaca aagaatacgt cagtttcttt tcgggtcatc
     2221 aacgagtgac aatcttagaa aatcaagaca ctcagttcta tcaagaagtt cagattattc
     2281 aagatcgtga gaatccagtt gccattgaag ggattggtag cgtccatcat gttgcgtttg
     2341 gcgtagaaaa taaatctgat ttacaacgca tcgacaaaca attacaagag cgcaatttta
     2401 taaattcagg aataaaagat cgtgaatttt ttgtatcact ttattatcgt gacccaaatc
     2461 aattattgat tgaaattgct acaggggaag gaaacctaga tgcaaaagcg tatgaaaatc
     2521 aaagtccacg ctttgaagaa attcctttat ttttaccgca gtacttaaat ttcattcgtg
     2581 aacaagtgga gcaataatta gctaatcaaa tccatgacga agagtaagag gttgactcat
     2641 aagtcaaaaa ataaagaaaa acgcatcaaa tccattctaa agaatgttga tttgatgcgg
     2701 ttcctatttt tataaactat cattttcgac taataaaact acttatgagt cagcctctct
     2761 ttttttcttg atttttatac ctctttctag gtaaactaaa catctgccaa aaataccgtg
     2821 tctcattgaa acattctcaa ctatttcaaa ataaagggga gtaccaaatg aacgagtata
     2881 ttgaaattat ccacgcaaga gaaacaactt aaaaatgtca gtctcaaaat tcccaaaaat
     2941 aaaattagta tttttaccag cgtatctggt tcaggaaaat catcgattgt ttttgatact
     3001 attacccaag aagctggtcg tcaactgaat gacacctatg atagttttac ccgtttattt
     3061 ttacctaaat acagtcgtcc agaggttgat gagattgata atctttctac ggcgattgtg
     3121 gtcaatcaaa agaagattgg tggcagtgcg cgctcaacgt tagggacgat tactaacatc
     3181 aatgcgttat ttcgtgtgtt gttttcatgt tttgcaacac ctagtttagg atatgcaaat
     3241 gcttattcat ttaatgatcc tagtggaatg tgttctgtct gtcagggaat cggtaagacg
     3301 attgcatttt taataggatt gctttatttt tcggctattg ataatgctga ttttgtattt
     3361 tctgatccat ttaccgcaga agttttgtct ggaattgagg aacaggcaaa gaatcatggt
     3421 tattttgtat tggtgcataa tgttaattca gcagaagatg ttaaaactat tcagagaaat
     3481 tggcgttttg aggggttcat tgttgttggt gtacgtgtaa aagaattttt ggaattaaat
     3541 aacgtttttg atggtcctgt tgtttatatt gatacgcatc tttcaaaaga gacattaaga
     3601 gaacttgaac aacaaatgaa tcgtttattt gtaaatacaa atgattacca agctagtaca
     3661 ttggcagtgg aacatttgat tcattatggt catgagaaaa tagcgtttct ttcttttgac
     3721 tacattgtag gtgaaccaag tgttattcaa gaacgacatc aagcttatat cgatacatta
     3781 aagaaatatc atttaacctt taaatcgcat tggatatata acaactctga atttgagcga
     3841 atttatcaag aattagctga atttactgca attgttgtta ctggagatta tttagcggct
     3901 aaattagtaa aatttttaaa aaataagaat aaacgagtga tggaacaatt atcgattatt
     3961 ggatttgatg atattacttt tgcagaatta atggatcctg cgttgacaac aatacgacta
     4021 aatccaggta acaagggggc gattgctttt caccaactga ttggactggc caaacaagaa
     4081 gaaataaaaa atcaagtact actattagag ggagaattga tttctcgaga ctctgttcac
     4141 aaaatcaaat aaaaaagctc tgtgaaataa gtatagttaa caataaaata tccgaacgat
     4201 agagagaatg aactgtgatc tagcagttcc tcgtcgcaaa ttcactagaa ttagcattat
     4261 ttactctaaa ttgttcggat attttttctt gtttttaatt atgattacag tgcctatttt
     4321 taacgaaatt tgcttatttt caaaatgtat gattatatgt tagtaaacac tttcaaatat
     4381 gaaaagagga gctattatgg taggaattag ggatgttgca aaacgggcgg gtgtgtccat
     4441 tgcaacagta tcgcgcgtgc taaatgagga tccgacactt tcagtaaccg atgaaaccaa
     4501 acgaaagatt gcagaatcgg ttaattttta tcattatgtc aaaaaaagtc ccgttgcaaa
     4561 aaatttaaca aatattgcat taataacgac agtttctgaa gtagatgagt tggaagatcc
     4621 ctattttcga acgattcgca gagggattca agtcgaagca gaacaaagca aagtcaattt
     4681 gaagaaaatt attcgtttgt cagaaacacc gttggagcaa gacgatttgc taaaatgtca
     4741 aggtgtgttg attattgggc aggtgctatc ttctgtgatt gaagaagtat cagcaattaa
     4801 ttcgaatgtc gtagtgattg atgaccctag tattgaagct gaagtagatg cagtttatac
     4861 tgatttaaca aaagcaacga atcagcattt agatcgattg tataaaaaag gacaccgaaa
     4921 cattgcgttt atcggaggag gacgtgttcg tttagatagc caaggaaata aacacgtgtc
     4981 agatgatgat tatcgaaaaa tagcctatga gacgtggatg aaacaaaaag gattagaaaa
     5041 atatagtcaa atttatttag aaggctggac cacacttgac ggaatgcagg cagcagattt
     5101 acttttgaaa aaacatgcta aagataagtt gccgactgct atcatggtag gaaatgatcc
     5161 tattgctgtg ggggtttatc gttcacttca aaaaaatggt ctacatattc cagaagatat
     5221 ttcgattgtg agttttgata atattgaagt tgctgaattt ttaacacctg cattaaatac
     5281 ggtgaatgtg aatacagaag aaattggaaa actagcagtt cgcatggtta atgaacgaat
     5341 aaaagaagtt agaaatgttt cgatcaaagt gattgtttct aataatatta ttgttagaga
     5401 aagtgaaaaa aatatcgatt aaaaaagtaa acatccaaaa aagggtgttt acttttttgt
     5461 ttactaatat ttttagtaaa aaatctcgac aaaacattaa gtaaacagtt atggtgttgt
     5521 taacaaaaag aaaacgcatt caaaacagga ggaattaaga tgaaacattt caaaaaaata
     5581 gctttaacag ggatagctgt tttaactggg acattactcg cagcatgtgg tgggggagat
     5641 agtaattcta aagacgggca agtaacttta agctatgcga gttgagatac tgaccaagct
     5701 ccaggactaa gaaaaatgtt agatgaattt gaaaaacaaa atcctgatat caaagtagaa
     5761 atggagacaa cgccttggga tcaatattgg gttaaattag aagctgcaac aacgggaggt
     5821 aatatgccag atgtagtaac catgcactct agcgaatcct ataaatatat gtcacagaat
     5881 gctttgatgg gacttgatga tgttatcaaa gaaaatgata ttgacatggg aaactttact
     5941 gaaggaattg ctgatttcta tacgcttgaa gacgaactat acgcaatccc taaagatgct
     6001 tctgtagtgg ggctatggta caacaaagaa ttatttgata atgcaggtgt cgattatcca
     6061 gatgaaacat ggacatggga aacactcaga caagctgcaa ttgatttaac agatgaatca
     6121 aaaggcatct atggttttgc atcacatatt ggaacagaga ctggctactg gccatttatt
     6181 tatcaaaatg ggggagaagt atttgccgat gacaatacaa aatcaggttt gaatacccca
     6241 gaagcacaag aagctttagc tttttatcga gatattgcac ttgttgatca tgcttcacca
     6301 acaattacag aattacaaga tcctgataag ttaagtcgtt ttcaatcagg tagattagca
     6361 atgatgattg aaggaaactg gtttgcaccg ggatttttga aaaatgacta tctagttgaa
     6421 aatgttgctt ctgccgtgtt acctaaggga aaagttaatg caacaattac aaatggactt
     6481 ggttgggctg ccagtgcgag tacaaaatac ccagaagaag tgaaaaaact aatggcattt
     6541 ttagctagtg aggacgccaa taaaatccaa gcggaaacgg gggcatcaat cccagcacta
     6601 aaaggctttg aagacgagtg ggctgcttct tcagatacaa ttgatttgag tgcttttgga
     6661 aaaatgttgg agtatggagt ccctcgtcca tacaataaag atggattacg agctgaacaa
     6721 gcagaagttc aaattattaa ccgtattctg tctggtgaag taactgttga agatggaacc
     6781 gctcaaattg aaaaagaagt caatgcgata ttgagcggaa attaaattag ttaattatac
     6841 aatatacagg cgaaaggatt ctatttcgtc tgtatattaa tggatgaata ccaaaaaggg
     6901 ggatattatg aaaaatcgaa tttttggaaa atatcgtaaa gatcaagtga tatggggcta
     6961 tatttttatt tttccaacgg cattaggatt aattttatta aatatatggc cagcaattca
     7021 aacagcaatt ttaagttttc aaaaaacggt agggttcggt gatactgaat gggtcggatt
     7081 aagaaattac caaaaaatgt ttgcagacgg tgaagttttt cagtctttat taaacacatt
     7141 aatttatgca gtggtttcga tacctagtat tgttgtatta tccttgttgg tggcagtttt
     7201 aatgaataga aaagttaaag gattgtcgat ttatcggaca atttattttc taccagtcgt
     7261 tgctgcacca tccgcagtcg caatgatttg gcgctggatg ttcaataatg attatggact
     7321 gattaataac atgttggcta aaataggtct cgatggacca gcatggttaa cggatccatc
     7381 gattgcgatt tattctatta tcattgtagg agtttggagt gctattggtt ataacatggt
     7441 gttattacta gccggcttat aagaaattcc taaagattat tatgaagcag cggaaattga
     7501 tggtgctagt ccaatccagc agtttttcaa cattacgtta ccattagtta caccaacatt
     7561 attttttgta gttgtaacaa cagttatcaa tgctttccaa gtatttgatg ttatttttat
     7621 gatgattact cctaatagta ccgccatgtt taaatcacaa tcattagcct atttattcta
     7681 taaacattca tttattttaa atgacaaggg atatggttcg gcaatcgtta tgttcctttt
     7741 agtgattata ttaattatta ctgcaattca aatgaagttg cagaaaaagt gggtaaacta
     7801 ttaaggaggc tatcaaatta tgaaaaataa atttttttca aatgcgccaa tccatatcat
     7861 gcttatttta ggtggtattg caatggcatt accttttatt tggatgattt taacttcagg
     7921 gaaaacgttg gttgaatcta cccaaattcc acctacaatt ttccctgaga aatttcagct
     7981 aagtaactat caacaagtac ttgatttatt accattcatg gctttttata tcaatacatt
     8041 tttaatggtt gttggacgag tgattggctc ggttttattt tcagcaatgg ctgcatatgc
     8101 ttgtgcgcgt ctaagttttc cagggaaaaa tatccttttc agcttagtac ttattcaaat
     8161 gatgattccc ggttccattt ttattactcc acagtattta ttagcacaaa aattgggtat
     8221 tttaaataca attccagcat taatattacc aggggtagtt agtgcgtttg gtacgttttt
     8281 attaagacaa tttttcttag gtttacctga tgaattggag gaagcggcct atttagaagg
     8341 tgccaatatt tggacgatct ttttcaaaat tatgttgccg cttgctaaat caggattggt
     8401 tgcacttgga atattcacag cgttgtttgc atttaaagat ttaatgtggc cattgattgt
     8461 caatacttca attgataaga tgcctttagc tccgggatta gcaaacttac aaggacaata
     8521 tgccacgaac ttcccacaat taatggcagg ttcgttatta gcaatttggc caatagttgt
     8581 gatattcatc gttttccaaa gaaaattcat tgaaggaatt gctacaacag gtagtaaatt
     8641 ataaaactat taattagtga ttggagagta agtacatgac aaaaattaca tttattggtg
     8701 caggaagtac tatttttgca aaaaacgtat taggcgatgc gatgttaact ccaagtctac
     8761 aagatgcaca tattgcattg tacgatattg atgaaaaacg actaaaagaa tcaaatttaa
     8821 tgcttaaaaa tattaataaa aattcgaatg aaaatcgtgc tgatattgtt tcttattatg
     8881 atcgcaaaga agcgttaaga gaggctgatt ttgttatcaa tgctattcaa gtgggtggtt
     8941 ataaaccttc aacagtgatt gattttgata ttcctaaaaa atatgggttg cgacaaacta
     9001 ttggtgacac catggggatt ggtgggattt ttagaaccct acggacacta ccagtaatgt
     9061 tagactttgc taaagaaatg gaagaagttt gtccaaatgc ttggttattg aactatacaa
     9121 atccgatggc gatgttaacc atgggtgttt taaaagcgac gagtattaag actgttggtt
     9181 tatgtcatag cgttcaagta tgcgtaccag aattgtttga gcatttagga atagccgatc
     9241 aatatgactt aaatgacttt caatggaaaa ttgcaggcat taatcatatg gcattcttgt
     9301 tggaaattac aaaaaatggg gaagatttct atccaacaat tcgtcagtta gctgcagaaa
     9361 aaccaaatcc acatccagat tctgtacgtt ttgaattgtt gaaacgtttt ggttactata
     9421 ttacagaatc aagtgaacac aatgcagaat accatccata ctttattaaa tcaaaatacc
     9481 cagaattgat tgacgaatta gggattccgt tggatgaata cttacgtcgt tgtgaacaac
     9541 aaattaatga ttgggaaagc atgcgagagg acattgtaaa taatggggag ttaacacata
     9601 cgagaagccg tgaatatgct tcatatatca tggattctat tacgacagga actccgtcag
     9661 tgattgcagg aaatgtctta aataaaggct taatcacaaa cttaccgaca gatgtttgtg
     9721 tggaagtacc ttgtttagtc gataaaaatg gcgtgcaacc aacctatgtc ggtgaattgc
     9781 caacacaatt agctgcttta aatcggacga atatcaatgt tcaagaactg acagtagaag
     9841 ccgctttaac actagataaa tcaaaaattt atcaagcagc gtatttagat ccacatctat
     9901 catctgaatt gtctttaaca gatatcaaaa atttagtgga tgatttaatc gaagcacatg
     9961 gggactattt acctgaatat aattaaaaag aagctgaaag agtaaggaat tttcaattcc
    10021 ttactctttt cttagttaaa tttagtaaaa atattgacaa aacacttagt aaacagttac
    10081 attagtgtta acaaaaagaa aacgcattca aattgtataa ggaggagcat aaaatgaagt
    10141 ggtctaaaaa aattatttta gcttgtatag cactaggagc aacgatctct ttgactgctt
    10201 gtggaaaaaa tcaggaagat gcaagcggta aggtagaaat agagtttttt aatcaaaaaa
    10261 aagaaatgac tcaaacgatt caggagattg ctaaagattt tgaagcaaaa aaccctgata
    10321 ttcatgtaaa agttgtggat gtaccgaatg ctggtgaagt aattaaaaca cgtatgcttg
    10381 caggcgatgt accagatgtc attaatcttt atcctcaaag tatagaattg aaagaatggg
    10441 cgaaagctgg ttatttagag gacttaaccg aagaaccgta tttagagaat atcaaaaatg
    10501 gatatgcaca acgttttgct attgaggatc gtgtatatag cataccatta accgctaatg
    10561 tctatggttt ttactataac aaaactgctt ttgaggaaat ggggattcaa gcaccagaaa
    10621 cttgggcaga atttgaaaaa atagtagctg agattaaaga tcaaaacaaa gtaccgtttg
    10681 cgattgcagg agcagaaggc tggactttaa atggttatca ccaactagct atagcgactg
    10741 ctgctggtgg tgaagaggaa gcgaacaatg tttggcgttt ctcagaagtt aatggaatta
    10801 atgctgaaag caaagaaatg caaaaagatt ttaatcgatt agatttgtta agagaaccaa
    10861 aagctttgca aaacaactgg caaggtgccg gttataacga tacagtagtt acttttacaa
    10921 aaggtgatgc gttgattatg ccgaatggtt catgggcaat gccgatgatt cattcacaaa
    10981 atccagattt tgaagtagga acttttcctt ttccagcaga tgaagcaggt caaagtctaa
    11041 cgattggcgc aggagaccta gccttatcag tttctgcaac ttctcaacat aaagaagaag
    11101 ccaaacgttt tgtagaatat atgacaacac ctgaagcgat gcagaaatat tatgatgtag
    11161 atggtgcacc gtgtgctgtt gagggcgtta tcgagaatac tcaggattca ccattaagtg
    11221 gtttaactga acttgctttt actgatcgtc atttagtttg gttagccaaa gattggaata
    11281 gtgaaaatga tttttatacc ttaacaacaa attatttaca caatggcaat caaaaagcca
    11341 tgattaacgc attaaatgct ttctttaatc caatgaaagc tgacggaagg taggaaaata
    11401 aaatgaaaat aaaagaaatt ttaaatcgtt actgggcaat catttttgta gcaattccaa
    11461 ttattttgca gatgattttt ttctactttc caatggttca aggtgctttt tacagtttaa
    11521 ctaattggac tggtctgact tataattttg attttgtggg tttgaacaat tataagattc
    11581 ttttttctga tccgaagttt atcaaatcga ttggcttcac tttaattgtg acgctttgca
    11641 tgattgctgg acaaattggt tttggtattt tgattgcgcg ggcgttgaac gcaaatatta
    11701 aagggaaaac attctttaga gcatggttct tttttccagc ggtcttatcg ggcgtggttg
    11761 tttctttagt atttaaacaa atttttaact atggtttacc aaaaattggt agtatgttag
    11821 gcattgaatt tttacaaacc agtcttttag gaacaacatg gggagcgatt tttgcagtaa
    11881 tttttgtttt actttggcaa ggaattgcca tgccagtcat cattttctta gcgggttttc
    11941 aaagtattcc acaagaaatt attgaagctg ctagaatgga tggggcgaat gataagcaaa
    12001 ttttttggaa tattgaaatc acctacttat taccaagtat ttcaatggta tttattatgg
    12061 cattaaaagg tggcttaaca gcatttgatc aaatttttgc tttaactggt ggtggaccaa
    12121 gcgatgccac aacatctttg gggttacttg tttataatta tgcttttaaa aacaatcagt
    12181 ttggttatgc gaatgctatt gctttagtct tatttatctt aattgggatt gtttcactgg
    12241 cacaattaaa attatcgaaa aaatttgaaa tctaggaggt ttcccaatga aaacatcaaa
    12301 agaaaaaaat atttctaaat acttgctttt attattaggg ggcttcatga ttttagttcc
    12361 cttagtttca acgctattcg gttcatttaa aacaacaccc gatattatga ataatttctt
    12421 tcgttttcct aatccagcga ctttggaaaa tttccgaaga ttgttagcgg atggaattgg
    12481 tcattacttt tggaattcgg caatcatcac aatcattgca gtagttgctg tgacagcaat
    12541 tattcctatg gctgcttatt cactagcaag aaaaatgact cgtgggaaag catacggatt
    12601 gatgtattta tttttaattt taggaatttt tgttcctttc caagtaatta tgattccgat
    12661 taccgttatg atgagtaaaa ttggtttagc aaatatgtgg ggattaatct tactctatct
    12721 cacttatgcc gtaccacaga cactattttt atatgttggt tttattaaac taaatgtgcc
    12781 tatcagtctg gatgaggctg ctgaaattga tggggctagt cactttacaa cttatttcaa
    12841 aattgttttc ccaatgttaa aaccaatgca tgcgacgact attattctta atgctctatg
    12901 gttttggaat gatttcatgc taccattatt aattttaaat cgtgattcta atatgtggac
    12961 actaccattg tttcaatata attatacggg acaatatttt aacgactatg gtccaagttt
    13021 tgcttcctat acagtaggaa ttgtcacgat tacactagtt tatcttgctt tccaaagaag
    13081 tattatagct ggaatgagca atggagcagt gaaataacca ataaattatt ctcattataa
    13141 aggagttcat aaacttatga ttatatttga caatcacaca caaacatttc atttacaaaa
    13201 taaaaaaatt agctatctat taggaatcga agaaaataat tatttaacgc atctttattt
    13261 tggaaaaaag attacgcact attctggtgg gtatcgctac ccccgaacag atcgttcctt
    13321 ctcacccaac aatgcaaatg cgcaagatcg tttattatct ttagacacat taccattaga
    13381 atttccagga tatggacatg gtgattttag agaaccggcg cataatatta aattaggaaa
    13441 cggtagtcgt gtaaatgatt ttcgttatga tagctacgaa attcaaaaag gaaagcccag
    13501 cttagcggga ttgccagcct tatatacgga agatgatgat gaagctgaaa cgctgattat
    13561 tcaattgaaa gacgcgatta gtggattgac tttacagttg ttctacacaa tttatcaaaa
    13621 tcacagtgta attattcgtt ctacgcaatt agtaaataat agtgataaaa cagtggagat
    13681 taaccgctta gctagtcaat caattgattt tccaaatcgt ccactcgagt taattcattt
    13741 aaatggtacc tgggcaagag aacgtcaaat gactagagaa aaaattcata cagggataaa
    13801 agtattagat agtaaacgcg gatcaagcag ccatcaacaa aatccgtttg ttgctttagt
    13861 agatgccaaa acagatgaat ttcaaggaga ggcatatgga tttaatttag tttatagcgg
    13921 taatcacgaa acggtgattc aaaaagatcc atttgaccaa acacgggtca ttatgggaat
    13981 taattcattt aattttggtt ggcaactaaa aactggcgac tcatttcaaa cgccagaagt
    14041 cgtgatggtt tatagtaatg aaggtctgaa tacgttatca cagacgtatc atgaattgta
    14101 taatcaccgt ttaattcgtg gaaactatcg tttaaaagaa cgtcccacgt taatcaacaa
    14161 ctgggaagca acgtattttg attttaacga agaaaaaatc atgaatattg tcgatgatgc
    14221 gaagaacttg ggcattgaaa tgtttgtttt agatgatggt tggtttggcg gtcgtgaaaa
    14281 tgacttcact tcattaggtg attgggttga aacagaaggc aaacttgctt gtggtttgga
    14341 aaatttagcc aagcaagtgc atgataacgg gatgaaattt gggatttggt ttgaaccgga
    14401 aatgatttct gaagatagtg aactatttcg agcacatcca gattgggcat tgggtattcc
    14461 aggtcgtgac cgctcaatta gtcgaaatca atatgttctt gatttttcaa gacaagatgt
    14521 tcgtgataat atctatcaac aaatgacggc gatttttgat cgtgtaccga ttgattatgt
    14581 gaagtgggat atgaatcgaa atatgacaga agtctattct gtcttgttgg actcaacgat
    14641 gcaaggtgaa gtggctcatc gttatatgtt agggttatat gaatttttag aaaagttaac
    14701 aacgaattat ccaactattt tatttgaaag ttgttcgggt ggaggcggtc gttttgatgc
    14761 aggtttcttg tattacatgc cacaaacttg gacgagcgac aataccgatg ccgtggctcg
    14821 tctgaaaatt caatatggaa ccagcttagt gtatccaatt tcaagtatgg gtgcgcatgt
    14881 ttcagcagtc ccaaatcatc aaacaggaag agaaacgagt ttaactattc gtggcaatgc
    14941 tgcgatggct ggtgtttttg gttatgagct agatctaacg caattaactt ctgaagaaaa
    15001 agcagaaatt aaagaacaag ttgcctttta taaaaagcat cgccaacttt tgcaatatgg
    15061 aactttttat cgcttggaaa gtccgtttga aggcaatgat actgcatgga tgtttgtctc
    15121 aaaagaccaa acagaagcca tggtctttta tttccgagta ttagcagaag ctgcgcatcc
    15181 attagtcaca ttgaaattag caggattagc agaagaagca acttatcaaa tggaagatgt
    15241 aacatttgct ggcgatgaat tgatgaatct cggtttttat attgactcag aactacatgg
    15301 tgattatgcg acacaacgct tttatttgaa acagatatag tagcttgaat ttacaatata
    15361 agtgcaacac caaaagagac tcattccaaa cgaagaaaat atgttttatt tacacgcatt
    15421 tactaaaaag cagcctgatt tgaattggga aaatgaagaa gtacgtgaag aaatctatgc
    15481 aatgattaac tattggttag ataaaggact aggcggattt agaatcgatg cgatattaaa
    15541 catcaaaaaa aaactagagt atggcatctt tgaatctgat ggagaagatg ggttagcctt
    15601 cattgggccc tggattctta atcagtcggg cattgaagtg tggttaaaag aaatgagaga
    15661 gcggacattt aaaccacata atagtatgac ggtagcagaa gccgatgttc ctaatgaacg
    15721 tttagatgaa tatattggtg aagatggcta ttattcgatg gtttttgatt ttagttatac
    15781 ggatattgat gtacctgaaa ctggtgaatg gtttaaagat agccaatgga catggacgga
    15841 tatgcgtacc aatattttta cgaatcaatt agttacgcaa gataaaggtt ggggcgcctt
    15901 atatttagaa aaccacgatc aaccacgttc aattaataaa tatattccag aagaatggat
    15961 caatgattat agtaaaaaaa tgttggcgac gctttttatg ttactaagag gtaccccttt
    16021 tatttatcaa ggacaagaac taggaatgac caacatagaa atggcatcat tagaagattt
    16081 tgatgatgta gctacgcatt ctcagtataa acgggcatta gaatatggat tggcaccaga
    16141 gcaagcattg aaagctgtca ataaacgaag tcgggataat tctcgcacac ctatgcaatg
    16201 gaatacgcaa aaaaatgcca gattctcaac ttctgataat gtatggttaa aagtaaatcc
    16261 taattatcca gaactcaatg cagaagctca gttaaccaat caacagtcgg tattcaatta
    16321 ttatcatcaa ttaattaaat taagaaaaaa tagtgtatac aaagacgtgc taatctacgg
    16381 acaatttcta ccagtgaaag ataaaaatga acatattttg ctttatgaac gccaattaga
    16441 agataaaatc gtattagtta tcttaaacgt tacagcaaca gaacaagaat attatgtaga
    16501 tgaacagtac caacaagtat taatcaataa ttatgaagat gttttattag atcaaagtcg
    16561 aaaattgcgt ttacgaccgt ttgaaagtat tgtattagct aattatggag gacaattatg
    16621 aaaattaaaa acgaagcaat gctcatcacc tatgcagata gtttaggaaa aaacatgggc
    16681 gaattaaaac aagtcttaga caaacattta caaggtgtta ttggtggtgt acatctgttg
    16741 cctttttttc catcgacagg tgatcgaggc tttgcgccga gtgattatac gacagttgat
    16801 ccagctcttg gaacatggga agatgtggaa gcattaggtg aagattatta tttgatgttt
    16861 gattttatga ttaatcacat ttctcgtgaa tcaaaatttt tccaagattt caaaaaaaac
    16921 catgagcagt caccatacaa agaaatgttt atccgtattc atgaattttt cccagaaaat
    16981 cgaccaacac aagaagatat tgatttaatc tacaagcgta aagacaaagc gccgtttcaa
    17041 acggtagaat ttgcggatgg tacgacagaa gaggtttgga atacctttgg ggaagaacaa
    17101 attgatttag atgtgaccaa agaagttgtg aaagaattta ttcgagaaac catcaaagat
    17161 atggcgaacc atggctgttc tttaattcga ttagatgcgt ttgcttatgc gattaaaaaa
    17221 ttagatacca atgatttctt cgtggaacca gatatttggg aacttttaga cgaagtgcgt
    17281 caagaagcag cgaaatatga cgtcgaatta ttaccagaaa tccatgagca ttattccatt
    17341 caaatgaaaa ttgccaatca tgattattat atctatgact tcgccttgcc aatggtcact
    17401 ctgtattcac tttatagtgg aaaatcagaa cgtttagcca attggttgaa aatgagtccg
    17461 atgaagcagt ttacaacatt ggatacgcat gatggaattg gtgttgtgga cgctcgtgat
    17521 ttattaacag atgaagaatt ggattacacc tctgaggaat tgtataaagt cggggcgaat
    17581 gtgaagaagg tctattcaag tgccaattac aataatttag atatttatca aattaacagc
    17641 acctattata gtgcattagg cgataatgac cgtagctatc tgttagcacg tgcgattcaa
    17701 gtatttgcgc cagggattcc acaaatttat tacgttgggt tattagcagg aaaaaatgat
    17761 attgaactgt tggaagcaac gaaagaaggg cgtaatatta atcgtcatta ctatgattta
    17821 gccgaaattg aagaagaagt gcaacggcca gtgattcaac aattatttgc acttttaaaa
    17881 tttagaaatg aatctgcggc gtttgatttg gatggaacga ttgaagtagc aacgccatca
    17941 gaatcagaaa tagtgattac acgtaaaaat aaaaacggta gtgatagtgc aacattaacg
    18001 gctaacttgg atacgaaaga atttatcatt gagtctaaag atataaaaat tttcactagt
    18061 gttgcattaa aattttaacc tattccatag aacaaaaaat cctttatact agcacttgga
    18121 tgacttatcc aagaccaata aaaaggactc atacatggat aagtataaaa caaatacagc
    18181 atttaataaa tggttttctg ccataaaatt aggaaaactt tctgtcaact cccaaaaatg
    18241 tatttttgat tacaattcgt atcgtaaaaa actgtctttt gaagctgtgc tcaagctctt
    18301 tctctacgca gttaatgaag aaaaagaaag tttgcgtgat ttgagtacag ctcttatcga
    18361 ccgatcgctc caactagaaa ccgatgtgtc atcgattagt catacccaat tgtctcgagc
    18421 atttaatgca cttgaaccta aagtgttaga agaaattttt caacaactgt tagaaaaagt
    18481 tcaacatcaa atcaaaccaa ccaagcgaaa tcatctgtat ctgattgatt ccagtacgtt
    18541 ttcgcttagt ttaaaacgtc ataagtgggc gactttccgt caaacaaaat caggtgtcaa
    18601 gttacactta aactattgtt atatggacga tactacgatg tatccaactg attttacctt
    18661 aacaaatgcc catgaacatg atctcaatca actaccagta ttggtgaatc aaccagaggc
    18721 aacttacgtg tttgatcgtg ggtattagga ctttgaaaag atggatcaga tgcattggga
    18781 tggctatttc ttcgtcactc ggattaaaaa aaacaccaaa gttcacgtga tagatactct
    18841 ggaaacatcg ccagaaacag aaattctacg agacgagctg gttcgtttag gatctaaaac
    18901 ctatctaacc gccaatttcc gactagtcac tgttcaagat aagaacggac gtgtgtttca
    18961 atttatcacc aatcgaatgg acgtctcttc aaaagaaatc tctgatatgt atcacgctcg
    19021 ttggcaaatc gaattgtttt tcaagcacat caaacaacac atgaccatta aaaccttctt
    19081 ttctcaaagt gaaaaaggcg tgcagaatca attgatttta acgatgattt ccgctctcct
    19141 cacgtttctc atcaaattgg agacgaaaac ggaaaaatca gtgttccaaa tcaaacgatt
    19201 ctttcgttat ttactgtttc agccctttga atgttgtcta gaaaaattaa ttcccacatg
    19261 agaaaaaaga aatttggctc gttacttttg gttttcagtt gaataacaga taaaaaattt
    19321 tctggaaaaa gtcatcctct gcgtcagcac agtttttttt gacttatttt cagaggaaat
    19381 agttttcaga atattctaaa atgttttatg caacactagt gatatttttt agaattagat
    19441 ttctaatgtg cattttttga gtattaagga gcaagtatac aaagatttat aaagctgatt
    19501 aaatttgaat aaaaatatgc aggaacgcta ctatttttag tagtgttctt ttttatattt
    19561 gaataaaaaa tgtggtggtt aaatggtggt tataacaaaa aatgaattaa tgaaattagg
    19621 ttatgggaag tatcagtctg agagaatcat acgacaggca aaagcaatta tggtttcaaa
    19681 aagctatacc tattacgaaa atagaagatt aggactagta cctgttgaat ctgtagaaga
    19741 agttttaggt atgaagatag aggtagagga ggattttcag aatcatggtt aattttaaaa
    19801 aagataaaaa tgggaaatat cattttactg ctagtttggg attcgacaaa cgaacaggga
    19861 aaagagtaca aaaaaacgta gaggggttaa aacagttaaa gaagaaaaaa agcgtatacc
    19921 gaacttgttt ctaattatgg aaaagaagca gaaacttctc aaagtactat gttgtttgag
    19981 gagttttttt ataaattatt cctaccttat tatcaaggga aagtagaaga aagaacatat
    20041 aaaaatcggt tatctacaat caaaaaaact tttcttattt ctttaaaatg gagttaagag
    20101 aaatacgtcc aattgacatt caaaagtggc aaaataattt attgagcaaa tataaaaatt
    20161 cttatgtaag aaacatgtat gggatttttc agatgtcatt agatcgagca gttgttttgg
    20221 gactacttga aaaaaatcct gcaaaagtta ttggaaatgt gaagaaaagg aaaactacag
    20281 ttgatttttg gacaaaagaa gaatttacaa aagttatttc aactttttat attgatgatt
    20341 tgtaccaaca ttttggtttt atttgtatgt ggttactttt tatgaccgtt atgcgtttgg
    20401 gagaagccac tgcattaact tggaaagata ttgattttga aaataaaaac ttgcgtgtga
    20461 ataaaacact ctattataag agagccaaaa cctatgagtt tgtagaaccc gaaacggctt
    20521 ctagtattcg tacaatcgaa ctagacgaca atacaattac ctttttaaaa gcttggaagg
    20581 agcgtcaagt ttcaatagga ggcatgtcgt ttgtactttc ttataatgga acacctactc
    20641 agaaatatac aatccgtcat attatgagaa gacatgcaac gatcgttggt gttcatataa
    20701 tccgcataca cggattaagg catagtcatg cttctttgct tatatcacaa taaaaagatg
    20761 cacttcgaat taaagaaagg ttaaaacatg ctgatgtaca aacgacttta ggaacttatg
    20821 gtcatttgta tctaaattca ttgagagaga taacaaatga tcccacagat tatatccaaa
    20881 ctaatttttc taaaatcaaa ccgacaccta tttacgataa taaaaaataa atgataaaca
    20941 aaagtaggat cacaccaaaa gaaacacact agaaaaacta taatacaggc ttttctagcg
    21001 tgttgtttct tatttccgcc tatttataca ttatactcat aaagcattta atgcatcgat
    21061 cgtagccgca ttgtctatat gggtatataa agttgttgta ttggtacttg aatgtcccaa
    21121 ttgttgggca gttaatacca atgaatttgt ctgttggtag agtctagtag ctaatgtatg
    21181 acgcagtttg tgagggctga cttgaattct aaagcctttt gaatattttg ctaccatccg
    21241 ttcgattgca ataccggata tacgcttggc ttctccttgg taaattgcta gaaataaagc
    21301 tttttcgttt tctgttactt tatatcgttc tttccgaata gctagataat tagctaaata
    21361 ttccattgcg aatgctgcta tattgacagc atctctttta tttccttttc tagttactac
    21421 cacattattc ttatctaaag ataggtcatc taaattaata tttataacct cggagagtct
    21481 caatccagat cctaaaatca gtgcattgat cgccaggtct ctttctacat ctcgttgata
    21541 atagatcaaa gctcgtttac tcaaagtatt tttatattca ttggcaatat aatctagata
    21601 attttgtgta tccttatcta gaaataattt tttctcaatg gcattggcac gtgcagctaa
    21661 cgtagtttta tctgtgatgg ttgctacttg atccatagga ttattgtcta agtatggttt
    21721 tcctagagga ttattggaac ttttcgaaag atatttaaat agaaccttta atgccgtgat
    21781 atttctattg atagtagaag tagatagacc taagttatta ttatctttga gcttagtttt
    21841 tgttgtctct ttttttacat tttcttttgt gcgacgtttc aaatgagatt tgtacaagtt
    21901 taggtcatag gcagttaact gtcttatcga ggtgatagaa gtatcaggaa cgatagactc
    21961 actcagaagc cattcataaa agagcttata attttttaga tattctaaag tggttcgagg
    22021 tgattgatct ttatcctcac gatcttgaac aaaatctttt atataatcgg gcatatgaag
    22081 tatgattgta tctatttttt gatatatttc tgtatttttc atgtcattca tcctttcaat
    22141 aagtagggga gaagagtatc tctataattg gactatacca attatagaat gttttgtcaa
    22201 ttggtatgct ctaaaattta ttaatttgtt tcaaaaaaag catataaaca ggtatacgtt
    22261 taataattta aaataaatgg tatacataaa tagggaagga aatagaaggg agcaatctaa
    22321 attttttgaa ttttcttaat taattatata gaaagaacaa tctttctata gagttagaca
    22381 tgagagggac tatgcttgat ttaaaatcaa caagcgtata tactgtatat acaaagaaaa
    22441 aggagggaga agactatggc aattaaagaa agaaaattta gggaagtggg gaactcagta
    22501 gtattaacta tttcaaagga gtttcttaaa gaaaatgggt taaatcccgg agatacggtt
    22561 tttttagatg aagaaaaact tcgagcggca attacaaaaa aacaagcctt atctgatgaa
    22621 attgatttag caatatctca agcattaact gaatatgata ctacttttag agagcttgtc
    22681 gataaatgag tattcattac ctagaagcca aagatattat aaaaatgaat gtaatccaaa
    22741 taaaaaaata ctctcctaat gaaccccttg gtgtaaagga tgcgaatgct ttagaaatgt
    22801 gtgtagggca acttcgagcc tcagcttttg gtgaagaggt ttatccttcg atttatgaaa
    22861 aagcagctat cctacttata caattgataa agaaacatcc ttttcacaat gcaaataaac
    22921 gtactgcttt cttagctact tttgtctttt tgaaaatcaa tggacagctt ttagctattg
    22981 atcaaaaaga tgctgtaaat ttagcggtat atattgctac gtatgataag gatttcgatc
    23041 aactaaaata tgaagtgatc aacactataa agacacatac gcagcccatt taaggagtta
    23101 ctgtatgtgt ctttataggg ttattagctg ctatagcgaa ataattgaag taaattacaa
    23161 atagctataa ttcaaatcca actatataga aaacgtaaat tttctatata gttggattaa
    23221 gataacgact atttatttta tcatattttt actataccct atacttttac ttggtatatt
    23281 tatgaataat cgcaaattta cccctatact actagtttgt aagttagatt aataaaaata
    23341 ctaaagttat ttgttctttt attaaataca cctacaactt ataaattgat ggtatttaga
    23401 taacacgaaa gaataaaaat aacagctgat agtaaagttt gttgacgatt gctactcaat
    23461 cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact tatgaaatga aagacctttt
    23521 acatcttgca gaaatcggta ctgggattaa actaagcaat aaaaactaat gttcccctca
    23581 ttctttgaac ttctactatt tgatttattt attctgataa atgacgattt caccttcagg
    23641 atcttcaaat cccgtataga atttatttaa gatctcttca gtatcagtaa taggataggc
    23701 gataggccac ataccctttg atggttagaa taaactgctc aaaatctgta tcgtatgttg
    23761 gctttagcat attaacaaag gctatctcca aattataaac cataagcgtt gaatcgttct
    23821 taacaatttc aattcttcct aacccaaagt cagaagatat aattaccgga cttgccttac
    23881 ccttcatgtg ggttgttgag attccatatt taaagggaat tgtcggtact atcggcggtc
    23941 tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta gtctcctaag tccctttgta
    24001 gcggatatgg caccataatc tcattttatc gaagtgagtc atggtttatc tgttggccaa
    24061 ccaaaattga tacaatctaa cgatgcaccc tctacggcat tctaggggag tgcacttgca
    24121 ttcacccaat aaaaaccggc agttagcaaa gaacttatgt agtcgtatgt tcttactgtt
    24181 aacatacaag aggtctcctt tccacaattg cttagcagta aacgggaatt tacaaagcta
    24241 atctcttcca ttttcttatc tttgttctaa aagtcccaaa tggagcaact gtatttacat
    24301 gaataaattt atatacttcc catacagccg ttttggttgc ctcgtctgcc cattttcttt
    24361 tgtgtgcagt gaatagatct tcatcactca ttgaatcaat catcatgtta atatcatcaa
    24421 tattacgatt gagaatttcc tctaattctt tcaatggtag atgtgcatag gtatttgtaa
    24481 accacttata taactctcct aactgattcc atttaaattg atcagaaggc gttttaacag
    24541 ataatccatt tctttcatca ttttcccatt ttagaattaa attcgtccaa ccaacttgat
    24601 atgctaaatt ttcagcaggt gttctatcca cttcctcaac tcttttatcc ttcaattctt
    24661 caggaatagt ttcaaattct aaaatatatt tagtataagt cctatttatt tcttttttta
    24721 attcttcttt atttttatat gttctcatta tattacctcc ataaattcct aattgtctcc
    24781 tttaattcat ctataatttc atccacgata ttttaatccg ttctacaatg catatctgat
    24841 atgcattgac tgtctaactc atatgtgaat gatttataaa atatcccaac gtctcatcta
    24901 aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa tatatttctt ttgtagtaaa
    24961 atcggactgg tttgcatatc attttcttcg taaatatcaa aatcatgtta actactatca
    25021 attactaata aaaactacca ctttaagcgt taagaactgt taagtttagt taagtgagga
    25081 tagttcacaa aatccattgt taaacttcac gaaagtggta aaactcaaaa tgctttatat
    25141 aggattacag catcgctctt tcttcgattg cgcgttgggt aaaaaatatt atgaagtaaa
    25201 aattgacgat gacacgttcc ttacggctca tcagatgaaa cagctacaaa aacgaaatga
    25261 tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca tattcacgcc tcgctcgacg
    25321 aactattaaa ggtcaagatt tacctgaaga tcatcctttt taggaaattg aagcttttta
    25381 tgttgcacaa tgcatttata atactacaat gatgttttca ccagatattc ttctagggtg
    25441 cggtgtaatg aaacagatac acttgcaaaa gaaaattcac cgcgaattta ctaaaattat
    25501 gaataattat gttaatcttc cgaaattttt ttccaaaatt aagggatcaa gctggtgtta
    25561 tagattgttt aaggttggca aaaaaataac ttctttttaa acaattatag aaaaccgata
    25621 ctctgttaag ttggttgaca cggtgtcgat ttttatgact ttcttattct gaaacttcac
    25681 taacggacag tacctaaaaa gtctatagta tggacgttta cgagtactat tttatcaaaa
    25741 atgctgctca tttcaactta tatgttttag tgaactaccc ccactta
//
LOCUS       DAFELK010000040        25502 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFELK010000040
VERSION     DAFELK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.041"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            133..3660
                     /locus_tag="LP433_001918"
     CDS             133..3660
                     /locus_tag="LP433_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBL2006065.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="LP433_001919"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="LP433_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBL2006066.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="LP433_001920"
     CDS             7448..7789
                     /locus_tag="LP433_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006067.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="LP433_001921"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="LP433_001921"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBL2006068.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="LP433_001922"
     CDS             9146..11566
                     /locus_tag="LP433_001922"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBL2006069.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="LP433_001923"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="LP433_001923"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBL2006070.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="LP433_001924"
     CDS             13000..13737
                     /locus_tag="LP433_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2006071.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="LP433_001925"
     CDS             13751..14566
                     /locus_tag="LP433_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL2006072.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="LP433_001926"
     CDS             14579..15226
                     /locus_tag="LP433_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2006073.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="LP433_001927"
     CDS             15242..15898
                     /locus_tag="LP433_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2006074.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="LP433_001928"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="LP433_001928"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBL2006075.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="LP433_001929"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="LP433_001929"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBL2006076.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="LP433_001930"
     CDS             18240..18758
                     /locus_tag="LP433_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL2006077.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="LP433_001931"
     CDS             18865..19365
                     /locus_tag="LP433_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2006078.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="LP433_001932"
     CDS             complement(19645..20565)
                     /locus_tag="LP433_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBL2006079.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="LP433_001933"
     CDS             20730..21743
                     /locus_tag="LP433_001933"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBL2006080.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="LP433_001934"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="LP433_001934"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBL2006081.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="LP433_001935"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="LP433_001935"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL2006082.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="LP433_001936"
     CDS             complement(23383..24144)
                     /locus_tag="LP433_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2006083.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="LP433_001937"
     CDS             24333..25427
                     /locus_tag="LP433_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL2006084.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4423 c         5384 g         7248 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg tgcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgtttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 gg
//
LOCUS       DAFELK010000041        25102 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFELK010000041
VERSION     DAFELK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.042"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(841..1454)
                     /locus_tag="LP433_001938"
                     /pseudo
     CDS             complement(841..1454)
                     /locus_tag="LP433_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406632.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(2675..3379)
                     /locus_tag="LP433_001939"
     CDS             complement(2675..3379)
                     /locus_tag="LP433_001939"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012610.1,HMM:NF019322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2006085.1"
                     /translation="MIFDKVKEQIRKVYITTDRKSELLPSERDLAQEFSVSRPTIRKA
                     LASLEDEGIISKNEGRGYLVKPASEKYVDHELDSFIGFFQDAVQQGKKISSKIIQQTI
                     IPADSTISECLEIEQNTLVLVLERIRYIDDYPTCIAKSCIPLSVLPEIVEHDFAKESL
                     FSVLESRGIRLAYAKRSIEVTPPTDLENLYLDLEKNEPVFVFTSIGFAKNQKPFEYEI
                     SKYPAYKTKFESTVSK"
     gene            complement(3394..4263)
                     /locus_tag="LP433_001940"
     CDS             complement(3394..4263)
                     /locus_tag="LP433_001940"
                     /inference="COORDINATES: protein motif:HMM:NF012585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBL2006086.1"
                     /translation="MKIAVICSGGDSPGMNSALLAIKKTIDSEPDSEVVFFKNGYAGI
                     FKECIASVSLKEVEVFKAGTLIGTARFEKMRDLESRKIIIENLNKMEIDNLIVIGGNG
                     SLKGAELLKNESELQVSVIPGTIDNDFPNTDYTLGFDSALNTIIRSIDDLTSTANAHD
                     RIIIMEVMGRGCFALPEYASIANNTYWVERDDKEYLHLICKKFESEFYSPILLLPEGI
                     SNKQKIIEFITKNLPKETKYLNLAYLQRGSSPTFYDRYIGYLWGQLAAKELIEGKSGI
                     LSQKNGNIMLIPW"
     gene            complement(4371..5387)
                     /locus_tag="LP433_001941"
     CDS             complement(4371..5387)
                     /locus_tag="LP433_001941"
                     /inference="COORDINATES: protein motif:HMM:NF013539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2006087.1"
                     /translation="MFNFDQERFLKTQAGAVATNEQISNILESIASDLEEIYFIGSGG
                     VGILFDSTIEFARTRSTFPFHRVIAAEFMIHPNKTFSNKSLVVIPSLSGTTKETLELV
                     EYCNEMNVKTLALVGSPKTPLEKAATYSIYNDVLDDTSSENYYLQGLLIALFLMKQRN
                     EIDINQYNTYIEDLKKIPEALVHAKEQAEPMAKSFAKKHKDTSYHILTGAGDSFAEAY
                     YYGMCILEEMQWIKTRPVHAADFFHGTLELIEAGVSVIITEGEDDSRPLTERVKNFVP
                     KFTDVHVTVDTKDYDLPGISEDTRKIISPVVLATVFERISAFLEEERNHPLTTRRYYK
                     QMEY"
     gene            5577..8300
                     /locus_tag="LP433_001942"
     CDS             5577..8300
                     /locus_tag="LP433_001942"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012385.1,HMM:NF013070.1,HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2006088.1"
                     /translation="MKTKILKELNDLLNSYDFPQYFPEECNAQYIAQKFQIKRNTASK
                     HLNELMEQKKVVKINGRPVLFFPVHTIERYISHSLDSFEFSSIDSFREKISKKKADHF
                     FDDLIGAKQSLKEAVQQGISAMKYPGGLPIMYFGSSGVGKSYLVEKLAEYCRQTGIIH
                     ENAPFIELNCAQYFNNPELLTSQLFGHMKGSFTGADSDHIGIIEAADGGIVFLDEIHR
                     LPPEGQEKLFIHMDKGVFRRVGDSGPWRLSHVRYIFATTEQEENFFLETFRRRIPIVC
                     TLPNYQDREISERKEIVFHLLEKESTLINKEILVSEAALSFLIRLDLYGNIGELDGLI
                     KQTIANKLFSGSNKKYIEIHISDLPSRYLLTENIELKNQIASQRFYIFSNGNYVHDCD
                     ETSTVTTNLRGLIHRVSKYYSECHDVNRNSEEFRRFVKDQMAEFNDRFIYQKNSEVLV
                     KYYLPEIQNIVQKISPSLFVHLSGNTVQAIATYLAIRDQWGYGKENASANEIEKLYEN
                     LKCNYLTDLNVFLLIFENALDTTLTIWDKLYISLCVISETGNEAKDINAIILAHGYAT
                     ASSIANVANRLVNQFVIDSIDMPLDISFSEVIDRLLHYIEYRKPKDGLVIFVDMGSLA
                     QIKTEIEQVIEVPTMIINNVTTEMAIETAQLIQSTSDIQKVVKKLPYSQFEKQVLYPI
                     KIRKRTIVVSCNTGLGTSIKIKEMMENNLSKDLGIEFLPYENETLRDTQQLEFLIKTK
                     DIIAIIGTDDPRVSNIPYISLEELFDGEIGKLYKVLLRVYGKEIAEAINQNIVKNSSL
                     NRLIDSLTILDAEKVVNQIEESLKDYQMRVGKTLSSLSKINLYVHISCMIERLIRNQG
                     VSSYPAIDQFLKRYETEVASIQKALSKIEKLYNIKIPMEEIAYVCNIIVSY"
     gene            8428..8850
                     /locus_tag="LP433_001943"
     CDS             8428..8850
                     /locus_tag="LP433_001943"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose IIA subunit"
                     /protein_id="HBL2006089.1"
                     /translation="MRQILCMSHGPLAKGMIETLSIIVGDLDNIDFRCAYVDGNNDVE
                     MIIDDYLKESMGNETIVVTDIFGGSINNEWLRRLPDLSKVYLISGMNLSLLVDLYLKF
                     QLVSSDQIEEIIDHAIQASSGSIKFCNQLDYEQTVDDF"
     gene            8868..9338
                     /locus_tag="LP433_001944"
     CDS             8868..9338
                     /locus_tag="LP433_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2006090.1"
                     /translation="MIKLVRIDHRLIHGQVALTWTNAISADCILVANDEILNDPIQKT
                     TLKLAAPHNVKVVIKSIQDSIDAINSGKTDKYKLFVVTKTISDAKRLANGVEQIKSVN
                     IGSVKETSGSSALTHTIFVTEEERAELKGMVSEGIEVFAQQVPTDKAIDLKKSL"
     gene            9362..10144
                     /locus_tag="LP433_001945"
     CDS             9362..10144
                     /locus_tag="LP433_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2006091.1"
                     /translation="MDSLLVQAILLGLLTAFIVIDWMTGTNNLSRPIVSSVFVGLIMG
                     DLKMGIMMGATLELAFIGAITIGAARPPDTVSGGILGTAFAIATGKGAEFALTLAFPI
                     AALFLLVDNLLTLLVLPMIARKADRYAEKGELKNVSKMHVLGFILVKSLPRALFVGFS
                     FYLGSPVMERILNAIPTFVQDGINIAAGIMPALGFAILLQMLLKKDVFVYFVIGFALF
                     SYLHVPILGIAIFGACLAYIIVNMETKAAMGSRGEEMVEDDF"
     gene            10128..10958
                     /locus_tag="LP433_001946"
     CDS             10128..10958
                     /locus_tag="LP433_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014093338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2006092.1"
                     /translation="MKMTSSGKALTKDDLTKICIRSCALEASWNFERQQHMGFAFAMM
                     PALEKIYSGNEEEKQKAAQRHLEFFNTAPPLSTFIMGIVASMEEENAKNPDDFDTSTI
                     TSIKTALMGPLAGIGDSMFWGTLLVIGIGVGASLAKEGNILGPFLFLLIFNVPNFLLR
                     YFGVMQGYNFGTKLLENIESSGVMKTLTHAASILGLMVIGGMSGSMVSIKVAGSIGQG
                     DEATKIQSIIDGILPNLLSVLCVFLIYWMLKKGFKTTYVLFGIFIFGIIAAFFGFLTT
                     "
     gene            10993..11991
                     /locus_tag="LP433_001947"
     CDS             10993..11991
                     /locus_tag="LP433_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2006093.1"
                     /translation="MLNYNAKEMKKKGKRIYGIREDVEKIAKQAYDSGISNIFFTASG
                     GSVAVMQPFEYVLMTESSIPVYSMTAAELVLMGHKQLNEKSLVILYSKSGDTKETIKA
                     AEYLKERNVPTVGIVSKEDTPLEALSTYAINYLDGRPQEMPLYFLIMSIMNLNGEFPE
                     YTRFADELKNLPTALNSVREQADEKGKKYAEEFKEDPYQIWIGSGNLWGITYSYSMCV
                     LEESQWLRTKSVSSPEFFHGTLELVEKGVCVTLLKTEGETRLLDARVEKFAVQYTDKF
                     NVFDTKDYELPGISDEFRKYFCAPVMWAALGRVSVHLEDIRNHSLDKRRYYRVVEY"
     gene            12008..12862
                     /locus_tag="LP433_001948"
     CDS             12008..12862
                     /locus_tag="LP433_001948"
                     /inference="COORDINATES: protein motif:HMM:NF012515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006094.1"
                     /translation="MTAYVIGFGDNVVDYYENLNQKFPGGNAVNFAVNAKKSGVKAYY
                     VGSLSSDPDGVLLQHAISSEGVDISFSEVIDEPTEQAHVTIKDGDREFIGGVRGSRLT
                     PALSAELIDLMKNSSLVHTSCHSRTETKIKELKKYDVKVSFDFSDLDKYRTHEYLSDV
                     CPSIYIAQFSVATDDQEEINRLISECKDFEVPYLLFTRGSKSPVFVDTRENKTYEGFI
                     RKVESPHDTMGAGDAYFAAFASNFVLSKREKSMIEHVIDCFHKGANLAYETLMIDGSF
                     GHATPINP"
     gene            complement(13436..14686)
                     /locus_tag="LP433_001949"
                     /pseudo
     CDS             complement(13436..14686)
                     /locus_tag="LP433_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            15203..15394
                     /locus_tag="LP433_001950"
     CDS             15203..15394
                     /locus_tag="LP433_001950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006095.1"
                     /translation="MGKYSFEFKSTIVQEYLEGEGGLGYLAKIQGVRSKKGTRMDQSK
                     VRPKNLTFGGRYLYGKISF"
     gene            15375..16786
                     /locus_tag="LP433_001951"
     CDS             join(15375..15930,15930..16786)
                     /locus_tag="LP433_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL2006096.1"
                     /translation="MAKYPFELKLKIVKEYLSGVGEYRHLANKYGISSKSQVSDWVNA
                     YREYGEEGLLKKHQNQKYSVQFKLNALELYQTSEMSYREVASTLEMNNPALIANWMRN
                     FREAGIEGLSKEKGRPLTLTRKKENKKENTTTEERERIKALEKQVRSLQIENAFLKEL
                     RKLRKQEAQQRRKNQSHESSPASEDPFKLVELLETLKFPKATYMYWQKRFDRPNPDQE
                     IEEKMLEIRKEHKDYGCLRLKKELENQGIHVNKKKIQRLIKKLGIEVKSYTRKSRRYN
                     SYHGKVGTVAKNRIHRRFYTNICHQKITTDTTEFKYYEVDTTGVVRQKKLYLDPFMDF
                     YNSEILSYRISEKPNALAIMEGLEEAIQMTNDCPFRRTFHSDQGWAYQMNAYKNKLKQ
                     HKIFQSMSRKGNCLDNSPMENFFGLLKQEIFHGEVYRSLDELKTKIDQYIYYYNHKRI
                     KKKLNWRSPVQFREAVKTAV"
     gene            16861..18144
                     /locus_tag="LP433_001952"
                     /pseudo
     CDS             16861..18144
                     /locus_tag="LP433_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(18360..19172)
                     /locus_tag="LP433_001953"
     CDS             complement(18360..19172)
                     /locus_tag="LP433_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2006097.1"
                     /translation="MGDSKLTKKEINKVFWRSFALQGSESYTDMQGMGYSFSILPALN
                     KIYQGNDEKYYEAVYRNTEFFNTTPHISTFIMGMSLALEEENAKTDQFETETISSIKA
                     ALMGPVAGIGDSFYWGTFRVIAAGIGLSLAAQGNILGPILYFSIYTLLHFLGRYGCLR
                     IGYRMGANAIEKAFENNYLESFSLAASIVGLMSIGAMTSSLVRFTIPAVFKSKGGEIN
                     VQQMLDDIFPGILSLGLTFFVYFLLKKKVKVLWIILAIFVFSIVGVYIGLLG"
     gene            complement(19189..19920)
                     /locus_tag="LP433_001954"
     CDS             complement(19189..19920)
                     /locus_tag="LP433_001954"
                     /inference="COORDINATES: protein motif:HMM:NF015566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2006098.1"
                     /translation="MIECILIGIVGYLTTIDERYFGASMMNRPIIVGPVVGLILGDLH
                     QGILIGAALEAMFIGIVTIGAALPPDVGVAGTIATALAIKSGAGADVAVTLAMPFAVL
                     AQGLNMLAFTINSFTVSQGRKAIENRKLSSFQKWHFFPLIVRLPSAVLTFLVVYFGAN
                     ATESFVNIMPEKLMTGFTVASGLLPAVGFAMLIQGMIDKKSVPYFFIGYLLAAYLGVP
                     VVGVAVAAIMVALLVIQTKRNPVNI"
     gene            complement(19937..20392)
                     /locus_tag="LP433_001955"
     CDS             complement(19937..20392)
                     /locus_tag="LP433_001955"
                     /inference="COORDINATES: protein motif:HMM:NF015769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2006099.1"
                     /translation="MIKLLRIDDRLIHGQVAMAWTKSVSADYIIVVDDASANDKMKQM
                     ILSLAKPVSTGLDIITSADFLSTFEKRKNQNLMIVTSSPKSAFEIVNAIPGEVDSINI
                     GGLRYAEGKEKVNEYVAITSEDKNYLAKLKESGFKLIMQATPTGKAKIY"
     gene            complement(20385..20795)
                     /locus_tag="LP433_001956"
     CDS             complement(20385..20795)
                     /locus_tag="LP433_001956"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2006100.1"
                     /translation="MYTIILASHKNLAKGMKETVEYILGPAPFIKVMTAYTDDNYDIE
                     KDTNILLDGTDKVLVITDLLGGSVNNHWMNYVYEKKLTKKITVIAGMTLSLIMELSMN
                     IEDYKLREKISMIIAESQKSIINCSELMEVEDND"
     gene            complement(21326..22285)
                     /locus_tag="LP433_001957"
                     /pseudo
     CDS             complement(21326..22285)
                     /locus_tag="LP433_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23146..23361)
                     /locus_tag="LP433_001958"
     CDS             complement(23146..23361)
                     /locus_tag="LP433_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBL2006101.1"
                     /translation="MKKFIIPCIFLFLSILLFSTSILVGSYLDSSGMLIEPAFFCVPL
                     GYLTLGLAFFTALYSFVKQRLLKKYSA"
     gene            23844..>25102
                     /locus_tag="LP433_001959"
     CDS             23844..>25102
                     /locus_tag="LP433_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2006102.1"
                     /translation="MKKSAKDRVFDELIRLTGNMSSVTAEKISKNLGISRQNASHYLT
                     RLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQINEAFHSVVGHDGSLREVIQKCIAAV
                     KYPPNGLSVLINGATGVGKSFLATKIFEYAIHEQIIEEDAPFAILNCADYADNPELLS
                     ATLFGYKKGAFTGAEKDTEGLLATANNGYLFLDEVHRLSKENQEKLFVFIDTGNYRPV
                     GENVNWHSAKVRFIFATTEKSEDYLLDTFDRRIQISVMLPTFEDRPIRERLELIQLFF
                     QNEADILQKDIIVSKEALSLMLSHPFSGNIGKLKNIIKISCADVYSRTREEPLTIGKN
                     EILIQLNMLESEVESLPIASLLIKKNQKIKTDRIKPFDYDSILEKITQLINEGNFNEK
                     FSSIKNEVQHLVHHIDKDSFLSMSRKL"
BASE COUNT         8230 a         4059 c         4789 g         8024 t
ORIGIN      
        1 cgaaaccatt taaataccca caagaaatga agcgagcatg gcgtaaaatg ttagatgatg
       61 agttgattcc acttgaaaat gaattgaggt aaatgagaag agttaagaaa attgtacgat
      121 tcaaagatag tagtaaagtg gaagtgtaga aaatagggat agatgtcttt tatttgttca
      181 cattttataa cgaagtattt aagacagcta ttgaataatg tttcctccac ctttttcatt
      241 catttacccc accccgttgt tatatgaccg tgtttcgaga gaaaccaata aaaagcatag
      301 gctaactagg ggttcctttt tcttttgatt ttttggaatc cgcttaagtg aaatgtatct
      361 gaaatgaaac agagataaag tgattttttg ctgtaatgac aaggttttag ctgtttcaga
      421 taccatgtaa cccaaaatag tttattgaga aaataggaga gtatttgata ctaactagta
      481 ggaaaaaatg agataaaaag taaatggaat catttcaggt aatctcaaat aaaaaatata
      541 caggcctgtg gcactttacc tacgggactg tatatttttt actctcagcg ggcttgtttt
      601 gactccgtgt ttgactccgt cgtattgatt ttaaatgata ttcgatgacc aattaatagg
      661 tcgtttttga aatttttgtc tctatatgac tcagtttgat aattattgat agatcgattt
      721 gggtctatat cgaacaaggg aagattgcaa aagtcgaagc ttaaaggatt gatattaaag
      781 gattaagagg taaaaaggta tccccataat atcctctgac tccgtttttg acctcgctta
      841 tcatccgttc atgtaagaat caaataattc gactgtttca ttttgccgat tttttgatac
      901 tttaatataa atgtccatga ttgttttaga agaagaatgt cctagcctat cttgtacatc
      961 ttttacttga gcacctgctt caaagagaag ggtagcatga gtctttctga agccatggac
     1021 tttgattatc ttcatatctg ggaacttccg tgctacttta tccatgacat ggttagggta
     1081 gcctttgtaa aggaagtccc tttttttatt ccctttgata gtgctgatta caggtatatc
     1141 atctatatta tctatccgaa tccctctaga aaggttcttt tatgttacag aacgtttcca
     1201 ttttttagaa tacgtaaggt tccattatca attgaaatta ctccctttga tttgtctgtt
     1261 tttgtaggat taatacatag agagccctcg gatagttcta ctaacgtttt gttgaagcag
     1321 atagtttgat tatcgaaatc tatgtctcta catgtcagtc cgagtatttc tccttttcgt
     1381 tcccctgtat aagaagctat tctaaagaat actaaagcac gctcatcttt taacttatgc
     1441 aaacattcaa aaaacagata tttcacatat atctaaaatt cggagattga aagaatgaat
     1501 ttatctaaga attttcacta atgttgcgaa tataatatca gaaaatttcg aaataaattt
     1561 tgttaaaaat tagaaaaatc cgaatactta gtagtggata aatttttttc aggaatagta
     1621 cgttttatta aaatgaaaac taatccgaca tcaacttttt tatcgaagca aacatcaagc
     1681 ggtaaaaaga cctctttagt ttgaaaagtg ttgctttcat attgatttaa attttggtta
     1741 agtaggtaaa ttaagaaatg atcagtgtaa gtatttcctg atttagcgca ccttgttcac
     1801 tttgaaaata caggtttttg atggacagat tttgcttcaa atgtttaaag aacatgccac
     1861 tgtacttggt acaggtcggc gcccccattt ggagttgcgt cagatcgagt cgtgacgatt
     1921 cattttgtac aaattagaat ttaaaattga atacatgacg cgcacatttt cccagagagc
     1981 catattctgt aattaatcac agcaattagt gattatgcac aatctaaaaa actgatttat
     2041 aataaaaata ttattcaaat aaataataat aactgcccgc atgatgttga cagttacaat
     2101 agcacataga tagactggca aagatggttc ttaatctttc actttggtca gaattcttgg
     2161 gttatccttc cagtgaaagt cagcagaaaa tccttaatgc ttacaaataa tttttgcgaa
     2221 ataggtttta ttggtaaagg actcaatcat gaatatgaat tacttttatc tggtaaattt
     2281 ggaaaaattt tgcaaagaaa taaaaattag acaaatttgc tacacataat caaagattaa
     2341 aaaagttttt aaaatatagt tgtttgaatg gggatatgaa ttagagaaaa ttggttgatt
     2401 caacgggtgc tatcattttt gatagcgtca tatgtgaagt aagcacacct aatgaaaaag
     2461 gttcaggctt gctttgaaga cttattaaca actatgtcga ctatccttga cttagggtag
     2521 aggagtacct ccacacacct taattagatg ataatgtttg gactgtaggc tacttagcgg
     2581 attaagataa agaggaagta gaaaaagagc cttgcggaaa gacactttat ctgttatccg
     2641 cgaggctctt tatacattta agcatattta aaaattattt ggaaacagta ctttcaaact
     2701 ttgtcttata agcagggtac ttagatattt catattcaaa cggtttctga tttttagcaa
     2761 atccaatact tgtaaagaca aagactggct catttttttc taaatcaaga taaaggtttt
     2821 ctaaatctgt tggcggtgta acttcaattg agcgtttggc ataagctaat ctaattcccc
     2881 tactttctaa tactgagaac agggattctt tggcaaaatc atgttcaaca atttcaggta
     2941 aaacagatag gggaatgcaa ctttttgcaa tacaagttgg atagtcatcg atgtatcgaa
     3001 ttctttccaa gacaagcact aaagtattct gctcaatctc caaacattca ctaattgttg
     3061 aatcagcagg tatgatggtt tgttggataa tcttagaact gattttcttt ccttgctgaa
     3121 ccgcatcttg gaagaatccg ataaaagagt cgagttcgtg gtcaacatat ttttctgaag
     3181 ctggtttcac tagatacccg cgaccttcat ttttagaaat aattccttcg tcttctaaag
     3241 aagctaaagc tttccgaatt gttggacgac tcaccgaaaa ttcctgggcc aaatctcttt
     3301 ccgaaggcaa taattcagat ttccgatcag tggtgatata cacttttcga atttgttctt
     3361 ttactttgtc aaaaatcata gtaatccatc cttttaccaa ggtattaaca ttatattacc
     3421 atttttttga cttaatatcc cagattttcc ttcaattaat tccttcgccg ctaattgacc
     3481 ccacaaatag ccaatatatc ggtcataaaa agttggagat gatccacgct gaagatacgc
     3541 aagatttaag tatttggttt cttttggtaa atttttggta ataaattcaa tgattttttg
     3601 tttgttagat ataccttctg gtaaaagcaa tataggcgag tagaactccg actcaaattt
     3661 tttacatatt aagtgtaagt attccttgtc gtctctctca acccaataag tattatttgc
     3721 aatggaagcg tactctggaa gagcaaagca gcctcggccc atgacttcca ttataataat
     3781 acgatcatga gcattagcag tagaagttaa atcatcgatt gatcggatta tagtgtttaa
     3841 ggcgctatcg aagccaagtg tataatcggt attggggaaa tcgttatcaa tagtccctgg
     3901 gatgacagat acttgtaatt ctgattcatt tttcaatagt tcagctcctt tcaaggaacc
     3961 gttacctcca ataacaatta agttgtcgat ctccatctta tttaggtttt caataataat
     4021 tttccgactt tcgagatctc tcattttctc aaatctggct gttccaataa gtgttccagc
     4081 tttgaatacc tcaacttctt ttagagaaac tgaggcaata cattccttaa atattccggc
     4141 ataaccattc ttaaaaaaga ctacttccga atctggttcg ctatcaattg ttttttttat
     4201 tgctaataaa gctgaattca ttccgggaga gtcgccacca ctacagataa ctgcgatttt
     4261 cattttagat cctcctaaaa aaggtgactg cgattctatt ctcccattag agaaaatgaa
     4321 gcaatcaaat gggcaatgga gtcgcggtca cctttttcat atttttatga ttagtattcc
     4381 atttgcttat aataacggcg agtagttaaa gggtggttac gttcttcttc tagaaaagca
     4441 ctaattcgtt caaagacagt agctaagacg actggggaaa taatttttcg cgtgtcttcc
     4501 gaaatgccag gtaagtcata gtcctttgta tcaaccgtta cgtgaacatc tgtaaactta
     4561 ggaacgaaat tcttcacgcg ttctgtgaga ggtcgagaat catcttctcc ttctgtaatg
     4621 atgacactta cacccgcttc aattaattca agagttccat ggaagaagtc tgctgcatga
     4681 acaggacgag tcttaatcca ttgcatctct tctaaaatac acatgccata gtaatatgct
     4741 tccgcaaagc tatcaccagc accggttaaa atatgatatg aagtatcttt gtgttttttt
     4801 gcaaaagatt ttgccattgg ttccgcttgc tctttagcgt gcactaaggc ttcaggtatt
     4861 ttttttaaat cctcaatata ggtattgtat tgattgatat cgatttcatt tctttgtttc
     4921 attaagaaga gagcaatcag cagtccttga aggtaataat tttctgaaga tgtatcatct
     4981 aaaacgtcgt tatagataga atatgttgca gctttttcta ggggcgtttt aggacttcct
     5041 accaaagcta atgttttgac gttcatttca ttacagtatt cgactaactc aagtgtttct
     5101 tttgttgtac cagataaaga tgggataaca accaaagatt tgttagaaaa tgttttattg
     5161 ggatgaatca taaattcggc agcgataaca cgatgaaaag ggaaagtgct acgagttctc
     5221 gcgaattcga ttgttgaatc aaaaagaata ccaactcctc cagacccaat aaagtaaatt
     5281 tcttctaagt cagatgcgat ggattctaaa atattggaaa tttgttcatt tgttgcaacg
     5341 gcaccagctt gagtctttaa aaatctttct tgatcaaaat taaacataaa aatctctcct
     5401 ttgattacca atggtaatat tttgtttgca taaataaaat accacaggta ataaaaagtg
     5461 tcaaatattt tttaggaaaa ataccatagg tattgttaaa gtggaaagat gtttataaag
     5521 aatattgaat tttatagtga aaatcattta ttattaagta aaggaggtgg gttcatttga
     5581 aaacgaaaat tttaaaagaa ttaaatgatc tacttaacag ctatgatttt ccacaatatt
     5641 ttccagaaga atgtaacgcg caatatattg cccaaaaatt tcaaataaaa agaaatacgg
     5701 ctagtaagca tctaaacgaa ctaatggaac agaaaaaagt tgtgaaaatc aatggtcgtc
     5761 ctgttctttt ttttccagtc catacaattg aacggtatat atcacattca ttagatagtt
     5821 ttgagttttc ttcaattgat tcgtttagag aaaaaatttc aaagaaaaaa gcagatcatt
     5881 tttttgatga tttaattggt gcaaaacaaa gtttaaaaga agcggttcaa caagggatat
     5941 cagcaatgaa atatccaggt ggattaccaa taatgtattt tggatcgtcc ggagttggga
     6001 agagttactt agtggaaaaa ctagctgagt attgccgaca aactggtatt attcatgaga
     6061 atgctccgtt catcgagtta aactgcgctc agtattttaa taatccagag ttattaacaa
     6121 gtcagttgtt tggccatatg aagggatcgt ttaccggcgc cgattctgac catattggta
     6181 taatagaagc agcagacggt ggaatcgtct ttcttgacga aattcatcgt ttaccaccag
     6241 aaggacaaga gaaacttttt attcatatgg ataaaggcgt ttttcgaaga gttggagata
     6301 gtggtccttg gcgtttatca catgttagat atatttttgc gacaacggaa caggaagaaa
     6361 atttttttct agaaactttt cgacgaagaa ttccgattgt ttgtactttg cctaattacc
     6421 aagatagaga aattagcgaa cgaaaagaga ttgtcttcca tttattagag aaagagtcta
     6481 ctctgatcaa taaagaaata ttagtttctg aagccgccct tagtttcctg attcgcttag
     6541 atttgtatgg aaacattggt gagctggatg gactaataaa acaaactatt gcgaataaac
     6601 tatttagtgg aagcaataaa aaatatatcg aaattcatat ttctgattta cctagcaggt
     6661 acttgctaac agaaaatatt gagttaaaaa accaaattgc gagccaacgg ttctatatct
     6721 ttagtaatgg taactatgtt catgattgtg acgagacttc aactgtaact acaaatttac
     6781 gaggtttgat tcatcgtgtt tctaaatatt attcagagtg tcatgatgtg aatagaaata
     6841 gtgaagagtt tcgacgtttt gtgaaggacc aaatggcaga atttaatgat cgttttattt
     6901 accaaaaaaa ttcagaagtc ttagttaagt attatttacc ggaaatccaa aatattgttc
     6961 aaaaaatctc tcccagtctt tttgttcacc tttctggcaa tacggtccaa gctatagcta
     7021 cctatctcgc tattagggat caatgggggt atgggaaaga gaatgcttca gcgaatgaaa
     7081 ttgaaaagtt atatgaaaac ctaaagtgta actatttgac ggatttaaat gtattcttac
     7141 tgatcttcga gaacgccctg gatacaacat tgactatttg ggataaactg tatatcagtt
     7201 tgtgtgttat tagtgagacc ggaaatgaag cgaaagacat taacgcaatt attttagccc
     7261 atggatatgc gacagctagt agtattgcta atgttgccaa tcgtttggtt aatcagtttg
     7321 tcatagattc tattgatatg cctctagata tcagctttag tgaagtaatt gacagattac
     7381 ttcactatat agagtatcga aagcctaaag atggactagt gattttcgtt gatatgggaa
     7441 gtttagctca aattaagact gaaattgaac aagtaatcga agttccaaca atgattatta
     7501 ataatgttac aaccgaaatg gctattgaaa ccgcacaact gattcaaagt acgagtgata
     7561 tccaaaaggt tgtaaaaaaa ttgccgtatt ctcagtttga aaagcaagtt ctatatccca
     7621 tcaaaattag aaaacgtaca atcgttgttt cctgcaatac tggtttgggt acctccataa
     7681 aaattaaaga aatgatggaa aataatttgt cgaaagactt gggcattgaa tttctgccat
     7741 acgaaaatga aactcttaga gatactcagc aattagagtt tctcattaaa acaaaggata
     7801 tcattgccat tatcggaaca gatgatccgc gtgtgtcgaa cattccctat atttctcttg
     7861 aagaattatt tgatggtgaa attggcaaac tctataaagt tcttttgaga gtctatggaa
     7921 aagagattgc tgaggcaatt aatcaaaata ttgttaaaaa tagctcatta aaccgcttga
     7981 ttgacagtct tactatttta gatgccgaaa aagttgtcaa tcaaattgag gaaagtttaa
     8041 aagattatca aatgagggtg gggaaaacgt tatcatcatt gtccaaaatt aatctttatg
     8101 ttcatatcag ctgtatgatt gagcgactaa ttcgtaatca gggagtaagt agttatccag
     8161 caatagatca gtttcttaag cgatacgaaa ctgaggttgc ttctattcaa aaggcactta
     8221 gtaagattga gaaactttat aatattaaga ttcctatgga agagattgca tatgtgtgca
     8281 acatcattgt aagttattga taaaataaag tgacactatt cacagcgatg gaaatagtgt
     8341 cactttattt tttgtacgcc ctttcattta agtggtgaca gtaattggca cagtatttgc
     8401 taataacaaa gcgaaaggag ttcgggtatg agacaaatat tatgtatgag ccacggtcct
     8461 ctagcaaaag gaatgattga aactttgagt attatcgtag gagatttgga taatattgat
     8521 tttcgatgtg cctatgtcga tggaaataat gacgtagaaa tgatcatcga tgattatcta
     8581 aaggaatcta tgggaaatga gacgattgtt gtaaccgaca tttttggtgg aagcattaat
     8641 aatgagtggc taagacggtt gccagatctt tctaaagtct atttgatttc tggaatgaat
     8701 ttaagtcttt tagtggattt atatttaaaa ttccaattag tttcatctga tcagattgaa
     8761 gaaattattg atcatgcaat tcaagcatct tctggttcga ttaagttttg taatcagcta
     8821 gattatgagc aaacggttga tgacttttaa ataaaggagg gaagagaatg attaaattag
     8881 tgaggatcga tcatcgtttg atacacggtc aagttgcttt aacttggacg aacgcaatca
     8941 gtgcggattg cattttagta gcgaacgatg aaattttgaa tgatccaatt caaaagacaa
     9001 ctttgaaatt agccgcacca cataacgtga aggttgttat caaatcaatt caagattcga
     9061 ttgatgcaat taatagtggg aagacagata aatacaaact atttgtagtt accaaaacca
     9121 tttccgatgc taaacggttg gcaaatgggg ttgaacaaat taaatctgta aatatcggta
     9181 gtgttaagga aactagtggc agtagcgctt tgacgcatac aatttttgta acagaagagg
     9241 aacgagcaga acttaaagga atggtctcag agggcattga agtgttcgct caacaagttc
     9301 caacagataa ggcaatagat ttaaaaaaat ctttgtaata aaaaaataag ggggtaattt
     9361 catggatagt ctcttagtac aagcaatttt gcttggtctc ttgactgcgt tcatcgtaat
     9421 tgactggatg acaggtacga ataacttatc aagaccaatc gtatcttccg tctttgttgg
     9481 tttaattatg ggcgatctta agatggggat tatgatgggg gcaacactgg agttagcatt
     9541 tatcggagca ataacaatcg gagcggcacg tccgcctgat acggtatctg gtgggatttt
     9601 agggactgcg tttgctattg caactggcaa gggagcagaa tttgcgttga ccttggcatt
     9661 cccaatcgct gcgctattct tattagttga taatctacta acattgcttg ttctaccaat
     9721 gattgctaga aaggcagata gatatgctga aaagggcgaa ctaaaaaatg tgtcgaaaat
     9781 gcatgtttta ggttttatct tagtaaaaag tttaccacgg gctttatttg tcggattctc
     9841 attttactta ggaagtcctg ttatggaacg aatcttaaat gctattccaa cttttgtcca
     9901 agatgggatt aacattgctg caggcattat gccagcacta ggttttgcta ttttattgca
     9961 aatgcttctt aagaaagatg tctttgtata tttcgtaatt ggttttgcac tctttagcta
    10021 cttacatgtg ccgattctgg ggattgcaat cttcggcgca tgtctagctt atattatagt
    10081 aaacatggaa accaaagctg caatgggttc aagaggggag gagatggttg aagatgactt
    10141 ctagtgggaa agctttaact aaagatgatt taacaaaaat ttgtattcgg tcatgtgcat
    10201 tagaagcatc atggaatttt gagcgccaac aacatatggg ctttgctttt gctatgatgc
    10261 cagcgttaga aaaaatttat agtggcaatg aagaagaaaa gcaaaaagca gctcaaagac
    10321 atctagagtt ttttaacaca gctccgccat tatcaacatt cataatggga attgtggctt
    10381 ctatggaaga agaaaatgcc aaaaatcctg atgactttga tacttctaca atcacttcta
    10441 ttaaaactgc attgatggga ccattagctg gtattggtga ttcaatgttt tggggtacct
    10501 tattagttat cggtatcggt gtaggtgctt cattagcaaa agaaggcaat attttgggtc
    10561 catttttatt tttactaatc ttcaatgtcc ctaattttct tctccgttac tttggagtta
    10621 tgcagggata taactttggt acaaagctat tagagaacat tgaatcctct ggcgtcatga
    10681 aaacgttgac tcatgctgcc tcaattttgg gtcttatggt aattgggggc atgtctggaa
    10741 gtatggtatc aatcaaagta gctggttcta ttggacaagg tgatgaagca acaaaaattc
    10801 aaagtatcat tgatggtatt ttaccaaatc tgctgtcagt attatgtgta tttctgattt
    10861 actggatgct taaaaaaggc tttaaaacaa cttacgtgtt attcggaatc tttatctttg
    10921 gtatcatagc agccttcttc ggatttttga caacttaatt gaataatcta aataattgta
    10981 aggagagaac taatgttaaa ctataatgca aaagaaatga aaaaaaaagg caaacggatt
    11041 tacggtattc gtgaagatgt agaaaaaatt gcaaagcaag cttatgattc tggaattagt
    11101 aatattttct ttactgcttc tggtggatcg gtagccgtaa tgcaaccatt tgagtatgta
    11161 ttgatgactg aatcaagtat tcctgtttac tctatgactg cagctgagct tgtcttaatg
    11221 ggacataaac agttgaatga aaaatcttta gtaatcttat actcaaaatc tggagatacg
    11281 aaagaaacta ttaaggcagc tgaatattta aaagaacgaa acgtgccaac cgttggtatt
    11341 gtaagtaaag aagatacacc gttagaggct ctatcaactt atgcaatcaa ttacctagac
    11401 ggccgccctc aagaaatgcc actttatttc ttaattatgt ctatcatgaa tttgaatggg
    11461 gaatttcctg aatacactcg ttttgctgat gaactgaaaa acttaccaac ggctctgaat
    11521 tcagttagag aacaggctga tgaaaaaggg aagaagtatg ccgaagaatt taaagaagat
    11581 ccttatcaaa tttggattgg tagcgggaat ttatggggaa tcacctactc ttattcaatg
    11641 tgtgtgcttg aggaatctca atggttgcgt acaaagtctg tctcatcacc agagtttttc
    11701 catggtaccc tcgagttagt cgaaaaagga gtttgtgtaa cacttttgaa aactgagggg
    11761 gaaacacggc ttttagatgc tcgagttgaa aaatttgcgg tccaatatac agataaattt
    11821 aatgtttttg atactaagga ttatgagcta ccaggtatta gtgacgaatt tcgaaagtac
    11881 ttttgtgctc cagttatgtg ggcagcccta ggtcgcgtca gtgttcatct tgaagatatt
    11941 cggaaccact ctttggataa acgtcgttat taccgagtag ttgaatacta aaagtaggtg
    12001 attaattatg acagcgtatg tgattggatt tggcgataat gttgttgatt actatgagaa
    12061 tttgaatcaa aaatttccag ggggaaatgc agttaatttt gctgtgaatg caaaaaagag
    12121 tggtgttaaa gcatactatg tcggtagtct atcatctgat cctgatggcg tgttattaca
    12181 acacgccatc agttctgaag gtgttgatat ctctttctcg gaagttattg acgagcctac
    12241 tgagcaagca catgtaacta ttaaagatgg agatagggag tttataggtg gcgtgcgtgg
    12301 ctcccgattg acacctgctc tctcagcaga acttattgat ttgatgaaga acagttcatt
    12361 agttcatact agttgccata gtcgaacaga aacaaaaatt aaagaattaa aaaaatatga
    12421 tgttaaagtt tcttttgatt tttctgactt agataaatat agaacgcatg aatacttgtc
    12481 agatgtttgt ccgtcaattt atattgcaca gttttcagtc gctacagatg atcaagagga
    12541 aattaatcgc ttaattagtg aatgcaagga ctttgaggtt ccgtatcttc tttttacgcg
    12601 tggtagtaag agccctgttt ttgttgacac tcgagagaat aagacttatg aaggattcat
    12661 tcgcaaagtt gagtcacctc atgatacaat gggcgcaggt gatgcatact ttgcagcttt
    12721 tgcaagtaat tttgtcttat ctaaacgtga aaaatcaatg atagaacatg ttattgattg
    12781 ttttcacaaa ggtgcaaacc ttgcatatga aacattgatg attgatggct cctttggtca
    12841 tgctacacct attaaccctt agctttgtgc tttgggcttt tattgctgga atttgtatag
    12901 tagactcatc ataactatat ttttgtatgt gaaaaggcaa gaggctatga tgaaaataac
    12961 actggctaat tgcatgaggg agcatatcgt tgttaaagcg tcattgatag tatgaataaa
    13021 tatctcgata atattatatt gttatttact taatttattg attagtcaag caaagataat
    13081 cttctgttac ttaacgagac tagtaggtac aagcacttca tgttatgtac gacccaaaaa
    13141 tattgctgtt gattatttgc tgaaattatt gcgagcttca atttattttt aaaggacttg
    13201 gtaggctgcg tgatgaaata agacttggaa ggctgtctaa accaatatat agtagactaa
    13261 atagtaaaaa agagcatggt aattgtctct ttgtcaataa gtctaatggt aataagacaa
    13321 gttggagatt gagaatattt ttattgtgta acctattttg aagcgtactt aactagcccc
    13381 ggccaaaatc aaattttttc ggggtatatc aagggtttgc gtcaataaca gaatgttatt
    13441 tatctatcac gttccttggt ggcgtgtaga gttgatggtt acgtagtagc gtatctacca
    13501 gacgcgtaaa ttttcttgcg gttaagacgt gtgctcgttt gtgtttattt ttgggacctc
    13561 tttacatttg ctttgataaa aagctttata ttgaggaaga tattttttta cagagttgga
    13621 agcttcaact aagtagtatc taaaatagcg actcctttgt tttgtcagag gtgtattttg
    13681 tgaccgatag ttaacagatt gtttgccttt ccaacataag cctgcgtatt ttgccaattt
    13741 tgtttgatct tcaaatcgtt caatttgacc gatttcagcg attaatccag cggcgtgtac
    13801 ctttccaata cctggaacac tagtcaaata ttgatattct ggaataacga caacaaattg
    13861 ctcggttgct ttatccaagt ctttgatgtt cttttcaagc gcacgaattt cacatacaaa
    13921 aacatttaga acgacattga tggattctta tgcaagacta tctaaccgat aactcacggc
    13981 aattgcacgt tgaatcgatt tggcattttt ttctggatct ttaaagcgac atttcctttt
    14041 tcttttagta agtcacagaa agcttccaaa ggaagcacag ccaattcatc tagcgtgaag
    14101 tcttctgtca caagagtaat gacagtggca ctatagagac ttgtcgattc atcgcgcatt
    14161 tatcgagtaa gcgtattgca tttgtacgtt agattttcca gaaagtgttg ttttgtacga
    14221 gtgaagttgc ttaatgagtc gatagcgagt gcgtgttaaa cgctgtaaag ccacgtactt
    14281 ctcttctttg ataggagaag ttgtgaaccg ttgaatacgc aataaatcag caattcttaa
    14341 cgcgttgttt cgatcagtcg tatcttcctc aaacatgcga ctgaattgtt tcatccgaaa
    14401 aggattttca atcctcacaa gtgcattgag tttttttagc tctgcatctt catggaaaaa
    14461 catcgaagga tgaaagctgt acatggacgt ttaattccat ctcaataacg atttgaccga
    14521 agtgattgtt ttcattgaac acaagaatca gttctcgtgt caatggagcc ctttcaatgt
    14581 cattagcaac agaattttca gtcaatatag atagctgatc gtcgtctgtt aggaagcaaa
    14641 cgtctaattt ttcagaacta acgtcattac caacaaataa tttcatggaa taaaaaccta
    14701 ttttcgatat aaattctaga aaatgcttcg atactgtggg attccacaga aactcactgt
    14761 gtggtcacga cctcgcctaa tagaatacgg taataaaaga gctaatgagt tgatagtaaa
    14821 cacagcgctt tggataacag acttatgaag gtagacaaag ctacaggact gattagcaaa
    14881 ttctcgttga atcctttcca tacatccatt gtactctgag aaatcacaca ataacgaaat
    14941 aaattccgga aggaatatgt tattcaaaaa aatttgtgtt ttatagatac tttaaaagaa
    15001 acttattagg caaaatatat tttacgaaga ctgatgagtt gtgcaaaatc aaatctgagt
    15061 cagaatgaac ttcattctag ctcagatttt tgtttaatga cttcagtcag tttcttgcat
    15121 tacgtgaatg aaaatgggac tggtgatgtc caaaccctaa aaagttagac caaaatctaa
    15181 cttcaggggg gatggtattt ttatgggaaa atatagcttt gaattcaagt caacaatcgt
    15241 tcaagagtat cttgaaggag aaggtggatt aggatattta gcaaaaatac aaggagtgag
    15301 atcaaaaaaa ggtacacgga tggatcaatc aaaagttaga ccaaaaaatc taacttttgg
    15361 gggtcgttat ttgtatggca aaatatcctt ttgaattaaa actaaaaatc gttaaagaat
    15421 atcttagtgg cgtgggcgaa tatcggcatc ttgccaacaa atacggtatt tcaagcaagt
    15481 ctcaagtaag tgattgggtg aatgcctatc gtgaatacgg agaggaaggt ctattgaaaa
    15541 agcatcaaaa tcagaaatat tctgttcaat ttaagttaaa tgcgctagag ttatatcaaa
    15601 caagtgagat gtcctatcga gaagttgcca gcactttaga aatgaacaac cctgcgctta
    15661 ttgccaattg gatgcgtaat ttcagagaag caggtattga ggggctctca aaagagaaag
    15721 ggcgaccact tactttgact agaaaaaaag aaaacaaaaa agaaaataca acaactgaag
    15781 aacgcgagcg tatcaaggca ttagaaaagc aagtccgatc ccttcaaatt gagaatgcct
    15841 ttttaaaaga gttgaggaag ctgcgaaaac aggaagccca gcaaagacgc aagaatcaat
    15901 cgcacgaatc atcgccagcc tccgaggatc attcaaacta gttgagcttc ttgaaacatt
    15961 gaaatttcct aaagcaacct atatgtattg gcagaaacgg tttgacagac caaacccaga
    16021 ccaagaaatt gaagaaaaaa tgcttgaaat tcgcaaggag cataaagact atggctgtct
    16081 gcgactaaaa aaagaattag agaatcaagg gattcatgtc aataaaaaga agattcaacg
    16141 tctgataaaa aaactaggta tcgaagtaaa gtcttacact cgaaaatctc gacggtacaa
    16201 ttcttatcat gggaaggttg gcactgtcgc caaaaatcgt attcatcgtc ggttttatac
    16261 aaatatctgt caccaaaaaa ttacaactga taccacagag tttaagtatt atgaagtaga
    16321 caccacaggt gtcgttcgtc agaaaaagct gtatttagat cctttcatgg atttctacaa
    16381 tagtgaaatt ctatcttatc ggatttctga aaaaccaaac gcactagcca taatggaagg
    16441 attagaagaa gcaatccaga tgacaaatga ttgtccattt cgtagaacct tccattcaga
    16501 tcaaggatgg gcctatcaaa tgaatgctta taagaataaa ttgaagcagc ataaaatctt
    16561 ccagagtatg tctcgtaaag ggaattgttt agataactca cctatggaaa acttctttgg
    16621 tttattaaag caagagattt ttcatggaga agtctatcgg agtttagatg aattgaaaac
    16681 aaaaattgac caatatatct attattacaa ccataaacgc atcaaaaaga aattaaattg
    16741 gcgaagtccg gttcagtttc gagaagctgt aaaaacagct gtctaacagt taattttatc
    16801 gtacaaaaaa ggagtggatt tctccactcc ataaaagtct aactttttgg ggtcgctaca
    16861 aatgcttatc gagaatttgg agaagaaggc ctcttgcgta agcgaaataa gcgaagttat
    16921 tctgttcaat tcaagataga tgcgatagag ttataaaaaa cgggtgagct atcctatcgt
    16981 gaagtggcga atcatttagg gataaaccaa cctgcgttag ttgtcaattg gatgaaaatt
    17041 tttgttcaaa aggattgcac gggctctcaa aaatgaaagg gtcctcctcc attttgtcta
    17101 agaaagaata aaaggaagaa acaagcaaac tgacgcctaa agagcataat cgtatcaaag
    17161 aattggaaaa ataagtgcgt ttccttcaga ttgagaatac ctttttaaaa gaattgagga
    17221 agcttagaaa acaggaagtc taacaaagac gaacgaatca atcgcacgaa tcatcgacaa
    17281 cctccgagga tcattcaaat tagttgagct tcttgaaacc ttgaaatttc ctgaattaac
    17341 ctttatgtat tggcaaagac gatttgatcg aagaaattca gatcaagaaa tcgaagagga
    17401 aatgcttaaa ataagaagtc aatataaaga ttatggctat ttacgtatga caaaggaatt
    17461 gtgggaccgt gggttccatg ttaacaagaa aaaagtacaa cgtttgattc gaaagctgag
    17521 tattgaagta cgatcattta cgagaaaata tcgccgctat aatacttatc gtggaagaat
    17581 cggcatgatt acaaaaaatc gaattcatcg acgcttttac acaagcaact gtcatcaaaa
    17641 ggttacaaca gatacgacag aactaaaata ttttgaaatg gataaatacg gtgccaatcg
    17701 tgaaaagaag ctgtatcttg atccattttt agatatgtac aacagtgaaa ttttatttta
    17761 tcgcatttct gaaaagccaa gtgcgttggc tatcatggaa gctttagagg aagctatctg
    17821 cgcaacggaa tgtatctatc gtcgaacttt tcactccaaa aaggatggac ctaccaaatg
    17881 aaagcttata gtcataagtt gaaagaacat aagatcttcc aaagtatgtc ccgtaaggag
    17941 acctgcttag ataattcgat cattgagaac ttccttagtc tattaaagca ggaaatttat
    18001 tatggaagag actatcgtat ctttgaagaa ttgaagcaag ccattgatgg ctatattcat
    18061 tactacaacc atgagcgtat gaaaaggaaa ctaaactggc agagtctggt gcaatttaga
    18121 gtaatagcat tcaaagctgt ctaaaatcat caagaaaagc aaagaaaaac ggagtgaatt
    18181 ttctccactc cgaaaacatc tatctttttt aggtcactac agaatcaatt ctgattcatc
    18241 agacccataa attatagatc ctaataattt ataccatgct ctttttactc atatttacat
    18301 ttatctttgg gtattttatg gtttaagttg atgtctgatc tagttttatt ctggattaat
    18361 taacctaata atccaatata aactccaaca atactaaaga cgaagatagc aagtataatc
    18421 caaagaacct ttactttttt ctttaataga aagtaaacaa agaatgttag ccccaatgag
    18481 agaattcctg gaaaaatatc atcgagcatt tgctgaacat ttatttctcc accttttgat
    18541 ttaaatacgg cgggaatagt aaagcgtacc agagatgagg tcatggctcc aattgacatt
    18601 aaacctacga tagatgctgc taacgagaaa ctttcaaggt aattgttctc aaatgctttt
    18661 tcaatggcgt ttgctcccat ccgatatcca atacgtaagc agccatatct gccaagaaaa
    18721 tgtaacagcg tataaattga aaaatacaat attggaccta aaatgtttcc ttgggcagct
    18781 aaagataagc cgatgccagc agcaataacg cgaaatgttc cccagtaaaa actatcacca
    18841 ataccagcta caggccccat caatgcagct tttatcgatg aaattgtttc agtttcaaat
    18901 tgatctgttt ttgcattttc ttcttcaagt gctaatgaca tacccataat aaaggttgaa
    18961 atatgaggcg ttgtattaaa aaattccgta tttcggtaaa cagcttcata atatttttca
    19021 tcattccctt gatatatttt gtttaaagca ggtaatatag aaaaactata tcccattcct
    19081 tgcatatcag tgtatgactc ggatccctgt aaagcaaatg aacgccagaa aaccttgttt
    19141 atttcttttt tagttaattt agaatctccc ataattatca ctctcccttt aaatatttac
    19201 aggattgcgt ttagtttgga taactaataa agcaaccata attgcagcaa cagctacacc
    19261 aactacgggg actcctaaat atgccgctaa aaggtatcca atgaaaaaat aaggaactga
    19321 ttttttgtca atcattcctt gaattagcat ggcaaatcca acagcgggga gtaaaccaga
    19381 agctacggtg aaaccggtca ttaatttttc tggcataata tttacaaaac tttctgtagc
    19441 attggcacca aaatatacta ctaaaaatgt aagtactgcg gaaggtaagc gaacgattaa
    19501 tggaaaaaaa tgccacttct gaaaagatga taatttgcgg ttttcaattg cttttctacc
    19561 ttgtgaaacg gtaaaggagt taatcgtaaa agccaacatg tttaatcctt gtgccaatac
    19621 agcgaaaggc atcgccaatg taacagctac atcagcacct gctccacttt ttattgctag
    19681 agccgttgca atagtaccag ctacacctac atctggtggt agtgcagcac caatcgttac
    19741 aatgccaata aacattgctt ctaatgctgc tcctatcaag atgccttgat ggagatcccc
    19801 taagataagt ccaacaacag gtccaactat tatcggtcga ttcatcatag atgccccaaa
    19861 atatctttca tctattgtcg ttaaataccc aactatgcca attaaaatgc attcaatcat
    19921 tcttattccc caccttctaa taaatcttcg cttttccagt tggagtagcc tgcataatta
    19981 atttgaagcc ggactccttt aattttgcta agtagttttt gtcttctgat gtgatagcca
    20041 catactcgtt aactttctct tttccctcgg cgtaccgtaa accaccgata ttaattgaat
    20101 cgacttcccc tgggatagcg tttacaattt caaatgcgct tttaggggaa ctagtgacta
    20161 tcatcaaatt ttgatttttc cttttttcaa aggtacttaa aaaatctgct gaagtaataa
    20221 tatctagtcc cgttgataca ggttttgcta atgataaaat catttgtttc attttgtcat
    20281 tagcagaggc gtcatcaact acaataatgt agtcagcaga tacggactta gtccaagcca
    20341 ttgcaacttg accgtggatc aggcgatcgt caattcttaa tagtttaatc attatcttct
    20401 acctccatta attctgaaca gtttataatg ctcttttggc tttcagcaat aatcatggaa
    20461 attttttctc tcaatttata atcttcaatg ttcatactta attccataat taaggacaaa
    20521 gtcatacctg caattactgt aatttttttt gttaattttt tttcgtaaac ataattcatc
    20581 caatgattat ttacgctacc accaagtaaa tcagtgatga caaggacttt atcagttcca
    20641 tcgagaagaa tattcgtatc tttttcaata tcatagttat cgtctgtgta tgcagtcatt
    20701 acttttatga atggtgcagg gccaaggata tattcgactg tctctttcat tcctttcgct
    20761 aaatttttgt ggcttgcaag aataattgtg tacataatcc acctccattt atttataaat
    20821 aatataccat tggtaatcta aatgtcaata aattatttcg tattaagaat aaataaaata
    20881 cctttggtaa ttagtggggc gaatctaaaa actttaacta aaattctctt ttgtaaattt
    20941 ttttgaacgc ggctatcgtg gtgatttttt atttctgttt gtttaatgaa tttgtaaatt
    21001 aggaggtgat ttttgtgatg gtgtaaacaa agcctataaa aatgaagtaa agcattgtgt
    21061 tttgtccaga tgtcaaatct tttatgtatc ggttgtatgt atagtatgtt acacccaaaa
    21121 tagataaccc aagtccaaat ggagagacag atgttcttta tattactggc gaagacatga
    21181 agtattctta taaaatatct aaaaatgagt ataagtttaa agaaaataat ttatctatat
    21241 aaactattct gctttgatta gcaagtcttt caatcggtaa aatattattt gaatagatgg
    21301 gatatggttt attattttct aaatgtcaaa ttaagttaga caattgctcc tcacttatgt
    21361 aactcaaaaa tacttctaac gatgttcgat aatttaaaga tttccttggt atatgatttc
    21421 ttttggaggc aaccgccgcc acaaattttt ggtcaacctg attgaaatcc attgtattag
    21481 gaagtccgtc tttacgtaac aatccattag aatgttcatt taatccccgt tgtgacagcg
    21541 ttccaggatc tgcaaaataa atagaaatat cgttagcatt actcatgttt ttccaattcg
    21601 aaaattcttt tccgcaatca aaggtaatgg atttgaacaa gtttcgggga agcttttgta
    21661 gccagtcagt tgtcactttt tcaatatcta gtgctttccg tccttcgggt tttaaagtaa
    21721 taatcacttt tgacaagcgc tcaaccagcg tgatgacagc acttttatga tggacaccca
    21781 caatagtgtc gccttccaaa tgtccaaatt cctgttgaaa ttcaggatag tccgtgagac
    21841 gttctgaaat attccgtttg aaggcttgtt tccctcgacg ttctttatgc ccgttgggtt
    21901 tccgttttcc tttcatgggt agtttcgagc aatcaaatta gtttgtttta aacttgcgat
    21961 aaagggttcg aacagaacat gaaattgaaa actcagcacg accgataatc acatcgggtg
    22021 tccatccttg cgccaccttg tttcggatat acgcatcttg ttctgctggc aaacaaatgg
    22081 gtcgtcggcc gcaccgtgtt ttattttttt gatattgttg gtaatagtca tggatagatt
    22141 ggccttgttt caggaagttg tacacattgt agatggtctg tctggaacga tttgaggtct
    22201 tagcgactac ggtaacagat tgatgcatat tgaaataggc ttctatcatc acgagttcat
    22261 ttgttgtaag atgggtatag gtcatttgtc ttcactcctt ataattcttt ggtcggaact
    22321 attttgagtg tagcacaaat gactttttta gttgtctagc ttaattttac aatctgcgtt
    22381 taataaactc tcagtgggat agtttgactc cgtatatgac tccggttgat ttgattgaat
    22441 tcagatgatt atacatacta taaatttctc tattatgttg ccatttgatt tgaataatgc
    22501 tgaaagaagg attttagtct ataacgaaca agggaataaa accaataaaa aaagatatag
    22561 aatatcaata taacaaaaag agattgtgac ataattctct gaaaaaagct ctagaaatga
    22621 cgagtcattc gtcatttctg gagcttttta ggtaaaataa aagagtacga gaggatactc
    22681 gcactctaaa tcattcaacc cttgaaagga tcaaaatcat gcatacaaat tataacatga
    22741 atcaactcac tttagatatc acaacttctt attccaaaag aagatagcac cgctgggttt
    22801 gtcaatgaac tcgttgaaac ccttgaaatc aacgagccgt atctttttgg ccgccctagg
    22861 aattgtgatt tgagtgccat gttaaaattg gttcttttcg catattgaaa atgattgaag
    22921 aggactatcg gtattacaaa agacaatata accagcaggt gaaaaaatgg agaaggtaat
    22981 tccgaaaaaa gcttcttttg gcgattggga ataattgttg gtaatggagg aataaaatga
    23041 atgtttatgc agacgtttga tgtctacatc aacatccatt cttaatactc gaaggttcgt
    23101 tgttgaaaaa actaactttt cttcaacaga ggatttacgt gcaaatcaag ccgagtattt
    23161 cttcaataat ctttgtttga cgaaactgta taaggcagta aagaaagcaa gtcctaatgt
    23221 taagtagccc aacggaacac aaaagaacgc tggttcaatc agcattccgc ttgaatcgag
    23281 gtaagaaccg actaggatgg aagttgaaaa taacaaaata ctcaagaaaa gaaatataca
    23341 aggaataatg aattttttca tggtgtctcc ttctttgttt ttctagatta tatagaatag
    23401 aacctaggaa aagataagtg tgacaaaatt gataggtgtg aaaggcattg agatatcaac
    23461 cagctttatc ctttggagta tgctattgtg attaatgaga cagaggatgt gggaccagac
    23521 gatactgaat caacggaaat tgttctaaac caccatcaaa tagtagtttt tctagtattt
    23581 gaaggtgatt tttttatgtt cgaaagtaac tgtaaaaaag ataaataatc ggcagttatt
    23641 ctttcacata agtaggttgg atgcaggtga gagaagttta ttgtatgaga ggaagattgg
    23701 taatctaact atagttttat aactaatatc agtttaagct cgattatttt tgtttcaaag
    23761 taaaattgga acagaaatat agaatagaca tattgtagcc gatagtttat tatgcttcta
    23821 gacacgttga actggagggg aaaatgaaaa agagcgctaa agatcgagtt tttgatgagc
    23881 tgatacgact aacagggaat atgtcttctg tcactgccga gaaaatttcg aagaatctag
    23941 gtatctctcg tcagaatgcc agccattatt tgacgagatt agtggaagat aaaaaggtcg
    24001 agaaattacc gggaaagcct gttttgtgga agcctttaga tgaatatgcg gttgtagata
    24061 atacggagca aataaacgaa gcctttcatt ctgtggtggg tcatgacgga agtctgagag
    24121 aggtcattca aaaatgtatt gcagctgtca aatatccgcc taacggactc agtgtattaa
    24181 taaatggagc cacgggggtt ggaaaaagtt ttttagccac aaaaattttt gaatacgcta
    24241 tccacgagca aattattgaa gaagatgcac catttgctat tttaaattgt gccgattatg
    24301 cggacaatcc cgaactgctt tcggcaacac tgtttggata caagaaaggg gcctttacgg
    24361 gggctgagaa ggatacagag gggttattgg caacagccaa caatggctat ctttttcttg
    24421 atgaggtcca tcgtttgtcg aaagaaaatc aagaaaagct ctttgttttt attgatactg
    24481 gaaattatcg tccagtcggt gaaaatgtaa actggcattc tgctaaggtt cgttttatct
    24541 tcgccacgac ggaaaaaagt gaagattatt tattagacac ctttgatcga cgtattcaaa
    24601 tcagtgttat gttgccaact tttgaagatc gtcccattcg agaacggtta gagctgattc
    24661 aattattttt tcaaaatgaa gcggatattt tacaaaaaga tattattgtt tcaaaagaag
    24721 ctttgtctct aatgttatct catcccttta gtgggaatat tggtaagctg aagaatatca
    24781 ttaaaatcag ttgtgcggat gtgtacagtc gaacacggga agagccatta acgattggga
    24841 aaaatgagat cttgattcag ttaaatatgc tggaatccga agtagaaagc ttgccgattg
    24901 ctagtttatt gataaagaaa aatcaaaaga taaaaacgga tcgaatcaaa ccgtttgatt
    24961 atgattcgat tttggaaaaa attactcagc tgataaatga aggtaatttc aatgaaaagt
    25021 tttcttcgat aaagaatgaa gtacagcatt tggtgcatca cattgataag gattcttttt
    25081 tatcaatgag tagaaaattg at
//
LOCUS       DAFELK010000042        25079 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFELK010000042
VERSION     DAFELK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.043"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(3..2060)
                     /locus_tag="LP433_001960"
     CDS             complement(3..2060)
                     /locus_tag="LP433_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBL2006103.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(2174..2386)
                     /locus_tag="LP433_001961"
     CDS             complement(2174..2386)
                     /locus_tag="LP433_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006104.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            2573..3040
                     /locus_tag="LP433_001962"
     CDS             2573..3040
                     /locus_tag="LP433_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006105.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            3037..3279
                     /locus_tag="LP433_001963"
     CDS             3037..3279
                     /locus_tag="LP433_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBL2006106.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            3297..3599
                     /locus_tag="LP433_001964"
     CDS             3297..3599
                     /locus_tag="LP433_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006107.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            3671..5725
                     /locus_tag="LP433_001965"
     CDS             3671..5725
                     /locus_tag="LP433_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006108.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETDEVEVDPVEA
                     NEESTWTEGDFQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKVKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            5725..8337
                     /locus_tag="LP433_001966"
     CDS             5725..8337
                     /locus_tag="LP433_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBL2006109.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            8334..10712
                     /locus_tag="LP433_001967"
     CDS             8334..10712
                     /locus_tag="LP433_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006110.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            10773..11315
                     /locus_tag="LP433_001968"
     CDS             10773..11315
                     /locus_tag="LP433_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006111.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            11393..11725
                     /locus_tag="LP433_001969"
     CDS             11393..11725
                     /locus_tag="LP433_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006112.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            11726..12319
                     /locus_tag="LP433_001970"
     CDS             11726..12319
                     /locus_tag="LP433_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006113.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            12341..14035
                     /locus_tag="LP433_001971"
     CDS             12341..14035
                     /locus_tag="LP433_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBL2006114.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            14723..16600
                     /gene="ltrA"
                     /locus_tag="LP433_001972"
     CDS             14723..16600
                     /gene="ltrA"
                     /locus_tag="LP433_001972"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL2006115.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            16731..17108
                     /locus_tag="LP433_001973"
                     /pseudo
     CDS             16731..17108
                     /locus_tag="LP433_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            17108..18313
                     /locus_tag="LP433_001974"
     CDS             17108..18313
                     /locus_tag="LP433_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL2006116.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            18329..18973
                     /locus_tag="LP433_001975"
     CDS             18329..18973
                     /locus_tag="LP433_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006117.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            18984..19790
                     /locus_tag="LP433_001976"
     CDS             18984..19790
                     /locus_tag="LP433_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006118.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            19812..20042
                     /locus_tag="LP433_001977"
     CDS             19812..20042
                     /locus_tag="LP433_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006119.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            20588..20863
                     /locus_tag="LP433_001978"
     CDS             20588..20863
                     /locus_tag="LP433_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006120.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            20905..21327
                     /locus_tag="LP433_001979"
     CDS             20905..21327
                     /locus_tag="LP433_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006121.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            21346..22938
                     /locus_tag="LP433_001980"
     CDS             21346..22938
                     /locus_tag="LP433_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006122.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            22950..23285
                     /locus_tag="LP433_001981"
     CDS             22950..23285
                     /locus_tag="LP433_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006123.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            23432..23626
                     /locus_tag="LP433_001982"
     CDS             23432..23626
                     /locus_tag="LP433_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006124.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            23658..>25079
                     /locus_tag="LP433_001983"
     CDS             23658..>25079
                     /locus_tag="LP433_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006125.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKK"
BASE COUNT         9241 a         3910 c         5098 g         6830 t
ORIGIN      
        1 ttttatttga agattggatt cgcactaata aatacattat ctacgccaat tctaccagca
       61 gagtcaacta caaaattatg acctaatccg agaatacttt ggttattata aagtaaattt
      121 gcattatggg cagggctatt tttccatcct accatggcat cgatagcacc atcgtctgat
      181 aaaaggtcat caatatacag cccagtttga cttatgtttt ctcccttagc accgtagcag
      241 cctaagcttt ccaataaatc ttggaaagta ccaccaccag ggcgatagtg actgaagctg
      301 acttgtaatt ctttagctcg aatatctgca gcctgttgaa caatatcatt gaattgcatt
      361 ggggcaacac cattttgttg gcgataatca tttaaccaag caagttcttt ttgacgcata
      421 aagttacgta attcgtctaa tgaaatcttt ttatatttga atgtgattgt tttattttga
      481 tcgacgttat taatggatcg ttggccgttt ttatccacgg taacggtagg atcgtcattt
      541 ctgcacaaga aataattttg atcagtcatg tttttccaag gagtagcaaa gctatcccct
      601 tcgtatactg tttttgattc actagagaga acagcgttgg tatcagcatt tacatgatta
      661 acagtcacat taaatttacg agtgtagttg aaaatataat tttgactttc agtcacattg
      721 tttaaggtta ctgaatttgt tggttctacc cgatcgtcta aaacatatcc ttgaatagaa
      781 ggagcagtta aagtgacact gtcaccgtga gtgacattga ctatctgttc tttcaaaata
      841 ttaactcgtc cttcgttttt gtagttgtta ttgcacaaca aattgatttg atgcacttga
      901 ttataattga atgtgattgt tgtattacct gtgattgttt tgctttgagt atcattacca
      961 atcactttgt agctaaaatt atctttagcg ccttcgctat atttaaatgc ttttgcctta
     1021 gcagtgtaag tagaaccaga agttactttt gcttgatctg tagcaatcac ttgacctgtt
     1081 tgattgtcaa tatggttaat agtaaccgta tattcttttg gtgtttcagg tttgtgttgc
     1141 aaccctttaa atgcagcatc aagactattt ttagcattgt ttacttgtgt ttgagaaacc
     1201 ttagaatcgt ctagtacttt tttagcattg gataaagcag tctgaaaatt attccaagat
     1261 tcttctgtaa aatctccttt agcagttgat tttactcggt tgtataaagc ttgtaattca
     1321 gctttattca cagtaggaac tggttttttc tttaatcctt tgtaagcaga atctaattta
     1381 tttttggcac tatccacttg cttttgagtc gcttttgagt catttaacac tttcttagca
     1441 ttgtttaaag cggtttggaa tgcgttccag gtattgtcgg tatagtcacc ttttttcgtt
     1501 cccttaacgc tcgtataaag agcttctaga gccgatttat tcactttggg tttagaggtg
     1561 tcagcgccat accaaccgat accttcgtat ttccagccat agtctttggt taaccattgt
     1621 acttctttcc aacttgcagt gtagtgatgt gagccagatt ttacaccagg aaggaaaagg
     1681 cggtagatcg gtttattatt tttttcggca gaacgccagg caggcccttc ataagtccag
     1741 ccgtaatttt tagtcaacca tttcacttca tcccaactag ctgtgtaatg gtgatcacga
     1801 agacctttat tgtacaaacg atagacaaga tggccaccgc tagtcggtgc ttcccaggcg
     1861 gggccttcat aatttcccca ttttatcttt actagatggt cacgttcttt tttgctagag
     1921 gtgtaaaaat gttcattatt atttggattg taaaggcgat acatgacgtt agttgaagca
     1981 gcgtcaacag atccagcaag actaagtgag gcagcaaatg ttccaatagc taaaacagtt
     2041 tttggattaa ataatttcat tttttcaact cctaaattta attaaaaatg tttacatgat
     2101 tattatatat cggctaaccg atatagtcaa taaaaaataa gaaaagcctt atataatttt
     2161 ggcttttctt attttatttg ttagttgaag tattaatatc aacgatttct tcagccaatt
     2221 tatttaattt catagcattt atgaatctca tgttgtctat actagagcgt ttgttggcaa
     2281 ggtcacttac tgtagttaag ggtacgccag attctatgga tatagaacga actgatttac
     2341 cactatcaaa cagcaaccat tcgattttct ttttatcagc gtacatttca atgctccttc
     2401 ttgttttttc tttattatag ctcttttttg taatgaatca caatatcaag agaaaaattt
     2461 tctatagaaa ggtggatttt tatgagtatt cgttctccgt gtatccaaat gaggtttgtt
     2521 gctactttcg ttatttgata tactaaaaat aaacaacgaa agaaggaata aaatgaagaa
     2581 aaagcaacta tggtttgtct ctatgtttgc aatatttttt attattttaa gtggatgttc
     2641 aagtaataag aaatcggaag ctaaagaaga taatagttta ttgcaaccag gaactgtttg
     2701 gaaagaagaa gtaggtggtc ttattcataa tttaaaaatt atagatgata ctacctggga
     2761 atattctgaa agtgtatggc atccagatcc tgtacaaata acagttaaga ggcaaaaaga
     2821 ctatgaaggt ttagaaagat acaaaatagt agattctgca ggcattaggg aatttataaa
     2881 caaacctgat tcattattta ttgttgttcc ctatgagaag gatggcgtaa aaaaaataat
     2941 ttttcttgga tctagcaagg atgagaagcg aacgaaagag aaattaattc atgatggatc
     3001 agagttaaat aaatacaaat tacaaaagac tagtgagtga ttgctagtct ttttatttat
     3061 cctgaaggag gaatcacagt ggcaaaagtt aaaacaccat tcgaaaaagc cgcgtctaaa
     3121 atcttagaac gccgtggtgt ttctgaaata cagtggaaaa aagaagttct tgaaaaagca
     3181 caatttgacc tattacgagg aaaagataag gacttagaag aatatatcta tcaacgtgaa
     3241 cgtgaaaaac ttgtattcga tgaaattatt aaacattaaa aggagcgaat aatcttatgt
     3301 ttgaatcaat tacaatgaat tttttaactc aaccgaaagt agtagctgca gttgatattt
     3361 ttagagcatt acaaactgcc gcaactagtt tgaaaaataa tctgatgatt tttgctgctg
     3421 ttgcggcagt ggcttccatt gctcttggag gtattttctt cttctttggg cgaagaggag
     3481 ctgaaaacgg gaagacacac gtaggttatg tattgttggg ggtaggagtt attttagctg
     3541 ccgcttctat tgtagtttca atgttctcaa tgtttggaca aaccccacaa ggactataaa
     3601 aaaaacaagt aggaggagta aaaagtacgt ggctactttt tactcctttt tttatgaaag
     3661 gagaatattc atgtttttta cgatttcagg aaatgcaaaa ttggataaag agttaataag
     3721 aaaagcaacg aagaaagtgg gaaagcgtac ttccttttta ccgaaaacaa ttaaatattc
     3781 tgtcattgaa acggaagaac agctacatgt gttaggacaa gtgttagaac aagagaatca
     3841 atcttctgtt aaattgactc tcacgttaca tgataaagaa ggaaaaatag aaaaggctgg
     3901 cacagaatac gtttttggcc cactggatta tcaaatttca gaaggttttt atcctacatt
     3961 gatagattta atccgccttg atgtgtttaa agatacggat gaaactatga gtgtggaaga
     4021 gtcttatcga aacgaaaaac ttttacaagt tttagaagaa gagttagaga gcgaccaaag
     4081 aaaagtgaat caagtgagtg aagtcgaagt aaatgaagaa gtaccatggg aacgaccaat
     4141 ctttccaaag aaggagtcaa aagaaaaaga gacagtctat gttgacgaac aagctgatat
     4201 tccgactcag aaatcgatat ttgaggaaga gaacgatgtg atgggtcaat tggaggtaga
     4261 tccctttgaa gaaacaatgg aggatgaaga gacggacgaa gtagaagttg atccagttga
     4321 agctaatgaa gagtcaacat ggactgaagg ggattttcag gaatatattg aaccacttat
     4381 cagtgaagaa gtagaaaaaa acgaaacaga gatacaaaag gcaactgtat ttgattatat
     4441 tttggatcaa tatccgccag agcatgaatg gatgaaagaa aaaaacaaat tatttttaaa
     4501 tgagctttat tcgaaatatc aattacccca aacctatcaa gcatttttag agagtaaaga
     4561 agaattaatc tcacagggta aaggcacact tttagaacag ttagagtctg tccaatcaac
     4621 aaattggcat gagcttgcac aagaagattt attagccacc tttgaagaac gtcaacaaga
     4681 aacagatcaa gaaattaatg agtatgcgac ggaacagtcg tctaattggg agaaagtaaa
     4741 agaggaacta aataaagaag aacagcgagt gattgaagaa gaagtacaaa aagtcaaaga
     4801 gcggtacgaa aagaaacgcg acaatgctta ttccttgtgt gtagaaaaga tcaacaattt
     4861 tactaagacg aatcaagaag cgttatcgaa agaaaaagaa aacttgttaa aagaacgtat
     4921 taaagaacga aaagaagagt tctaccgcgg tttacgtaca gataagctaa agattagcaa
     4981 agaattaaat gaacaactga ataagctata tcaaacaacg actgaagttc ttatggaaaa
     5041 acacgaacag atccagcaag aattacaagt acaaattcca aaatggaaaa aagagtatga
     5101 aattcaacaa caagaattga aagaacaaga agaaaaacaa cggcaaaaag aaaaagagcg
     5161 tgaacaatta gaaataagaa aacgggaaca ggatcttgcg gaacaaaaaa tggcgataga
     5221 aaaacaacgg ttagagcaag aaaaggaaaa agaagcagct gctcgtaagg aacgtcaaga
     5281 acaaatggat acattgcgtc aagcacagtt gaattatcta gcacaacctc aaccagtagc
     5341 tgctgttcaa acgccagtga acaaccaagc aaatttaact ccttcacccc agcgttcctt
     5401 taacggatgg atggtgggat gtattgcaag tttaagcttg cttctaggtg gaggaacagt
     5461 atttgctttt aatcatatca atcaatcttc acaggctgat tctgtagcca caacggcgtc
     5521 aatcaaggaa gaagcccagg aacaagcaag aaaagagtat gaacaacaat tagaagaatt
     5581 attgaatcgt accaatcagt caacaacaga gtcaagcatg gaaaatagca aagagagtga
     5641 ttctagtaag gctaaagaag gatcaagcga ttcaactgta caatcaaaca cttccgaaag
     5701 ttcagaatca aatgaggtga aataatgcgt gttagagaaa caacgaagcg aaaagacaaa
     5761 cgattcaatt tagaaaagaa taggtatctt tctcatttct atcgctatac tccctcagga
     5821 gaagagctac cagaaaaaca tgacaaacgc atttcgaaaa agatttttta tagtggactt
     5881 gtatacctcc ctttagagta tttagtaaca agagtaccag aagttttcaa ccgattggaa
     5941 attgttaagg gaagcttaca aggaataaat ctgtttcaat tacaggaaat gccacaggtc
     6001 tttcattttg attcagctgg tttttggaat ccatttactc ctacaactag tttgggtaca
     6061 cgtttagcaa tttcgacagt ttgtgtggtt ccagctgtac ttatgggatt gaaaatggac
     6121 atgtggtttc gtcctctagc agatggacaa aaaggggata atcgattaat gaccttaaaa
     6181 gaaatccaac agatttatcc gcaaatacct gaaacaaaaa ctacttttcc aggttatgga
     6241 ggtattccaa tcacacatta caaaaaatat tggtacattc aaacagatac tgttaatacg
     6301 tgtattgttg gtacctctcg atcagggaaa ggtcagattg aagtgttagc caccattgac
     6361 aatttatctc gtgcagaaaa acaaagttca atggtcgtta atgatccaaa aacagaatta
     6421 tatgttggta gtaaagatga actagaagct agagggtatg atgtatatgc ctttaatatc
     6481 accgatccac tgcaatcaat gagtgataat ccattggcac tcattgtgaa atactggaag
     6541 cgaggagaca tagacaccgc aacacagtta accaatactt ttacgaatac gatttattat
     6601 gatgcaaatg cttcagacaa taaatacttt aacgaaaatg cgcagaaagc tgtcaatgcg
     6661 cttatttttg cgttattgga acaagcggat caaacagggg attactccaa attaacacca
     6721 aataatctcg ttgaactact ttcagaaatt ggcggtttta attattatcc agatcctgag
     6781 aatgaattca agcagctcaa tgccttagat gagttcatga atcagttacc ccctggaaat
     6841 atagcaaaaa aacaatatgg ggcaacaaaa attggatctg ataaagcgaa agggaatatc
     6901 ttgtctacgg caattacagg attgaatcca tttaccctaa cgaaaattgc gaagatgact
     6961 tctcaatcga ccattgatta caagtccatt ggttttccga agtatttgga tctcaaatta
     7021 catgaaagcc tattaaatca acgcattgtc gtggaatttt atcataaggg aaagaaattt
     7081 cacgaggaac gagtcaaagt tggctatcgt ggtttttgtg aaatcaactt tgattgtcat
     7141 ttagagcagg gagatcatgt ttgcttaaaa tacaatcatc aaggaaaaca atatgttgct
     7201 tggtatgagt tttctcaaaa agtattgaaa gacgaagagg gaaaaatcgt ttatcgaaaa
     7261 aaacgaggag aaactcattt gccagaacta gaaaaagaag ccgttctaac attagatgag
     7321 aagaaaagta acctattagt agagtctatt cggatgcact ataccgataa accaatggct
     7381 atttttatgt taacgcctga ttatgatcca tctaaccata tcattgttag catctttctt
     7441 agtcagttgt ataaagaatt atctacgcaa tgtgttaaga ctaaaggaga taaatgtcac
     7501 cgtaggattc attttatttt agatgaattt ggaaatatgc caccgatgga caacatggaa
     7561 ggaatcatga cggttacggc aggtcgtaat atgttatggg atctgtttat tcaatcttat
     7621 cagcaacttt atgcgaagta tggagaacaa aacgcagcga ttatcaaaga aaattgtcag
     7681 acacatattt atattatgtc gacagatgat aataccatcg aagaattttc taaaaaagtg
     7741 gggaataaga cggttgaaca agagaacagt accatcaatt cattaggtat gaatactcat
     7801 atcaatcgca atgttgattc agatcgtatc ttaactcctg aaagaatttc tactttttta
     7861 gaaggtgaaa cgattgtact cgctccttta aaacgacaag atttgaaagg tcataaaata
     7921 cggccgtatc ctatttttaa tcatggggaa acgaatcttc cttatgctta tcaatatatt
     7981 gaagatttca atccatcgtg ggatatcaat gatatagaca tacattgtac acatgcggac
     8041 ttggatctta aggctttaca aattgattat gattatttcc taccagatga atatgctaga
     8101 aatctctatc atggactgca tgatcaatta gaagaaaaaa acgaagaaaa tatgttttat
     8161 aaaatcgttc aatcttttga gaatgagacg gctaaaaaat tgttaattca attttacgaa
     8221 gaacaagcaa cggatcgtct tcaagaatat gttgaaaagt tgatcaaaaa tgaagaaatt
     8281 tctgaaatga ttaggaaacg gctgttattg gaagctgaaa aggcggtgaa agaatgatca
     8341 ttggaggaat tttctctggc atagccgact ggtggtcagg tttattcgga gaaggggatg
     8401 cagatcccaa aaccgtaacg aaagtcttac aagattatgg taattatctg cagtatcaag
     8461 atgtattcag ttggatttgt aatacttttt tatggggatt gatcaaaggg ttatataatc
     8521 tcaatacttt attagaaaaa acaatttatc aaagctttga tttaaaagac ttattgaacg
     8581 ccgctggtgt taatgaacta tttcaaagtt tgattagtaa ggtattggct cttttttgtg
     8641 tcgtcacatt aatttattta ggcttgaaat tttttatgag taaacaccca ccgaaagtca
     8701 aaaatatctt ggttaattta tttatggcca tgatcttgat ttttggtggt agttctttaa
     8761 tcgatgaagg gttaaatatc agtaaaaact tttatggaga cgtcactgca gcaaataaag
     8821 cagataaaac gggttcacct gcttttcaaa ttattcaaaa taatgtgatt gatgtcagta
     8881 cattactagc gactgacccg aataaagtag aatccttacc aacagataaa agaaatgctt
     8941 taacagcgaa aaatttcaaa acagcgaata tcaatgggat tattacacct gatcaagcta
     9001 agaaaatgtc tgaatcaagt gatattagta cagtacaaaa agatcggtta aaggcattac
     9061 agtatcgact agagttagac gataatggga aagaaatccc tgttcaaatt agtgatgaag
     9121 gtttagcaaa atatgtgtat acgtcaggct atcgtcgata cattagtagt ccagggatta
     9181 ttttggctgg ggaatcttct ttgtcggtag cctatttatt tattttgttt acaatcgtta
     9241 cttgcattat tgagctagta tttaaaaaat tctatttagt aattgccgcg tcaacggact
     9301 ttgagacagg acaacggatg aaaagtgcga tagaagatat ttctcaatcc ttcttgttat
     9361 tggcgtttac gattttagaa ttacgaatct atacattaat gctttcaggt atcggtgatt
     9421 tgcatgcggt aggaaagatc aatggattct tgtatgttgt tgctttaatt gtgctaacta
     9481 ttgcgctatt caaaggctct caatcggtta cgaagatttt cggtgttgat acgagtctga
     9541 aaaacggcag caattctctt cttagcatgt ttgccttagg aaatattgcg aaaaatgtgg
     9601 gtagcggagc taaaaacctt gcaagtgctg gtaagagtgg tttaagccat ttaaatgata
     9661 ttcgtaagaa tggatttggc catcgaaaag atattaccca tgataacggg gaagaacaat
     9721 cagacgataa agctacaact gtacctaata gtaagaagac agtttccgaa atgttcggga
     9781 aagcgaaaaa tggtgtttct aaagccgcag aaggtcttgg ttacgtcaat gaacgtgggt
     9841 taaaaggaac agttgaagat cttacagaaa aagccaaaga caccttagaa gagaaattag
     9901 acggcacgag agctaaagaa tttgctgaag ctgtgaagaa tccatccgaa gcactagaaa
     9961 aacaaaaaga aaaagcttca gcagtcaaag aaggactaaa agatgcgtat ggtgaaggac
    10021 aagtcaatgc agcagtgaag gcaaatacaa caagtgaaaa agaaaatcaa gaaggtgcag
    10081 cgattccttc agccaaagat caccaagatg agttacattc taacgaaaat tcgatcggag
    10141 aaaaagattc agaagaagga caacatggtc agttaccaaa aaccgatcca gaacaatatc
    10201 gttataaatc taacattaat tctgaaaacg aaaaacgcat ttcagattta ccaaaacgaa
    10261 atcaagaagt acaaacggat gaggattcca tcgatctgcc aaatgataat ggcatcgaag
    10321 ttggaactga aaaatcaacg aaaattggtt tgcctaagac acaaaattta ccaatgaaag
    10381 atagtcgttt gaatcaattc aaagagaatg atcaaagctt tgttcatcaa tcacctgcag
    10441 gtactgttca aatgaaatca agtcgtttgc ctgaaaatgg aaatctgaca actgtttctt
    10501 acaatttagc tgaaagtggt gaaacagaga atgcgtccgt tcaaaatatt gtgacaaaag
    10561 aagctgcacc taagccaatc aataaagttc ataatggata cagaccagca aacgtagcat
    10621 ttactgcacc gacaaaaata aatgtgacaa gagaaactaa aaacaggaac aatgaattga
    10681 aagaacaact attgaaggat atcaaaccat aaaaggccta tttaagggcc tttttcttta
    10741 taaaacaagt ttaaaatgga aaggagaaaa ttgtggagga tattttaata gctacgttta
    10801 taactgcact gggagcattt ttaacgatat ttgtggtgac tattaaagga tttaaagata
    10861 cggatagttt acaaaaagat catcagtcta ttttagatgg tcaaaaaaca cataccgaaa
    10921 gcattattgt acacctttca gaaggattca cttatttgaa agatgctatg cccacattca
    10981 cagtaaaatt aacggaaata tttcattctg ttgagcaaat atcgtcagaa ttgaaagagc
    11041 aaagacaaca aaaagatcgt caacttggct cacttaattt taggcaagaa acgatacaag
    11101 aatcattgga gaatgtaaat cgattaaacg atgaaatgca acgagttcat ttggaaaatg
    11161 aagaattacg cgcacaaaat tatgatttaa ttcaaaagaa aagaaatctg gaacaaaaaa
    11221 ttgttgaatt aaaagaagaa aatcgtcaat tgaattatca attacgacga ggaaaaaatc
    11281 gttctcgtga tttaggaaat gaattagagt tgtaatattt agaaaaacgc tgtgagaaat
    11341 cacagtgttt tttatttcta aaaatacaaa atataagggg tatggttata ttatggataa
    11401 atacattcat atgaaaaatc ctccaagatt tagtggggaa tggaagtttt tcgccttttt
    11461 ctttttagat ctattaacgc ttggtggctg ctttttttgg gcgaaaatag tcaataatct
    11521 tgtccactta ccactctttt ttgcactctt gaattatgga ttatggcttg cgatagcgtt
    11581 agtgattgtt tggcgaccct ataataaccc tggtcaacgc caaatttttg cgattatcga
    11641 atctattttc tttacggata agaaccacta tcatgcgtta gatcctaacc gaaattatca
    11701 tggtacgtat aaggaggatg aataaatgcg agtcaaagga caaaattcag ttgataagaa
    11761 atccattttg cagtttggaa aaccagaaga gcgctctatc ttggacttat ttccatataa
    11821 atcctgtaca gaagagggag tcttaattac tagagaagat cattttcagc gttattatcg
    11881 tgtcgtttcc actgacgtgg agggattaaa tgaacaagag aaactagaac gaatgaatca
    11941 gttgaccacc gtcatgcgta cgtatgtgcc aacaattaag ttagttagtt tgaccacaga
    12001 gacggatcta acggaacaaa tcgtgcaaaa gcggcagtta ttagataaaa atcgtatgga
    12061 acagtcacta ggaagaaatc tacagcgatt aagaaaatat gaaaagaaat tagtagagga
    12121 gatccaggaa ttaaaacggg cagaacaaga acgtcctgac ttaagcttct ttttcgttat
    12181 tgaaggaaag acaatcaagg atttacaaac tagaaatcgt cagttaatgc gatctagtgg
    12241 cattttaggg ttaaaaccac tctacaaaaa agaattgatt aagattcttt atcgaatgaa
    12301 caacatgaat gacgaataaa aaagatggag gaaatgattc atgctagatg tgataaaaac
    12361 agctttttca acgcaaagta atcaaaaggt gattgatcca ttaaaacaac ttggtaatcg
    12421 tgaaatagag attttaaaat caaaaggtta tgatttagat ttcttaaaac aagtgatgcc
    12481 acaaggtggg ttgaattttg atgaagaata tgtgacctat ggaaatggtt attcacgatg
    12541 tgtgacagtt tatcattaca caaaaaatcc tactcttttt tggttggcca atctcatgaa
    12601 caatcctcat acagtggcca cactagatgt tagcacagat gaaaagcaaa aagtgattga
    12661 tcaaatcaac cgcgcattag atgaattaaa tgatcgatca gataatgaac gaaaagcgac
    12721 tgaccgaaat aaaagtgcgg aagaatacct ggaactagcg gaatatgccc gaaaattgac
    12781 ttctaatggg gaaatttcta aacaagtcaa agtgagagta catgtttacg gaaatacgat
    12841 ccaagaagtg gatgaacggg cgcaggaact gatcgaaaat ctaaaaggga tggattatcg
    12901 tgcggtgact tatctgcata aaaccaaacg agattggcaa tcgatgttta ccatgttcga
    12961 tgaacaagct gaatggtttg gaaatatcaa agggcaatca cttccatcgt taaacattgg
    13021 cggaggattc ccgttccacc accaaacgct aaaagatcca ggaggcacac aatatgggga
    13081 aaccatgaca ggcggcccat ttgtctggaa tgccacgtat aaaaatagtg tacgtttatc
    13141 taccaatacc ttgcttctag gaatgatggg agctggtaaa tcgaccgttc ttaaaatgat
    13201 cgcggaagcc catttagctg caggagactt tatttggggc tttgaaaagg gaaaagactt
    13261 tattcctttc ttaaaggaat ataacggtat tatggtgcgt ttagacggat ctgacggaat
    13321 gatcaatcct ttagagatat ttgccacacg gacgtatgat gaagcatcca gtttatatga
    13381 cgatggatca gtcaaagatt tgaagatcaa tgaagcagcg tcctatcaaa cacacttaga
    13441 caaagtggtc tatcaggtac agttagtgag tcctcagcta aaaggaacga tgaaagcaga
    13501 atttaagacc tacttaaatc gtttttatga agagtatgga acagtaccac gcggctttac
    13561 ttcctcaaat tcgcgttcaa atactgatac gcaagtcaca gggaaagatc cagaagctta
    13621 tccgacgttc aaagaatttt tagccttttt aggacaactg gaactaccag gggcttccca
    13681 agagaaaaag aatcggaaag aagaaatgga gtctatcgtg gaatccttat gtgagactta
    13741 tggcatgatt tttgatggtc atagtacgat tcgacacctt gaccaacaac agttggtctt
    13801 ttttgacatt gactctatta caggcctaga tcgaggggta caacaatgtc agatgtacat
    13861 ggccatgacg ttgatttgga atcaggcatt gattcaagga cgaagacaac gacgcttaat
    13921 taaagaaaaa caaatggaag aacaagactt caaacgcttc ttggcgatga ttgatgagtg
    13981 ccataatggt gcgacctgtt ctgcagtgaa aagctgtggg ttgcaagtag tctaaaaact
    14041 attgtaataa ctcttataac gagaagtcaa atgagtgggt aacgccacaa agggcttcca
    14101 ctgatactcc gacatgcaac aagtagttta tgcagaccaa cgttgtgtga agctcggtga
    14161 agtcggctga aggataccgt aaggtaaaag aaatagtgaa taccacgaaa gttctctaga
    14221 ggtaaagggt gtatccgata agtcgggtgt ccaaaaaaac ttaatatggt gagtatgtac
    14281 aaacgtactg acgaactagc gaatgtactg tccgaaaggc atagctccta gaaatgggag
    14341 agacagtgag caaaaaatca ctcattgtgc taacttgtgg ttgagtaaaa gtcgttgtta
    14401 tgaaagacca tgctgcgtta caggcgtagg agaagttagg gggcaaaagc tagcatctaa
    14461 gttaaggcat gtggatagat ataagggaac aggggaagcc atcaacatgg agagtgcata
    14521 ctcgatgaag tggtagtaag aaatatgtga atgacaaata acttacttta gtgatggtga
    14581 aagtagagtc acgactgatg aaggttctgt aatggaactg gaggaacagg ctcgattcgt
    14641 ctgtaaaagt catgaaaccc gttcaaccat gggattctcg tatgactaaa aaggtcacga
    14701 gccaattgga gcgtgataaa ccatgacaaa agaaacaagt ccaaaagata ggaagttgcg
    14761 gcatgcagaa tattatggca tgacggaaat cttcgataag atatactcca aaagtttgaa
    14821 gggagataat ttcaagaatc taatgcagat tatcatttct gataacaaca ttgtcctagc
    14881 atatcgtaat atcaagagaa atcacggtag tgtgacaaga ggagaagatg gagtaacgat
    14941 taaagatatt gaaaatctca accgtaatga attcgtagaa attgttagga agcgattcgc
    15001 acattataac cctcggaaag taaggcgtgt agaaattcct aaatataatg gtaaattaag
    15061 accgttgggt attccatcaa tatgggatag aatcgcgcag caatgcatct tacaagtatt
    15121 agaaccaata tgtgaagcaa aattcaataa tcacagctat ggtttccgcc caaatagatc
    15181 agcagaacac gcaatagcag attgtatggc ccgaatgaat caaagtcaca tggaatatgt
    15241 ggtagatgta gatatcaaag gtttcttcga cgaagtcaat catactaaac tcatgagaca
    15301 aatctggtct atgggtatac gagacaaaca gcttctctta atcattagga aaatgttaag
    15361 agcacccgta gtacttccaa atgggaagtt gatataccca acaaaaggaa caccacaagg
    15421 cggaatactt agcccattac ttgcgaacat caatctcaac gaatttgact ggtggatagc
    15481 aaatcagtgg gaggaaaaag atgccaaaga gctaaaacat cattttagga aaaatggagc
    15541 ttgggataaa ggtaatatct atcacaagct cagaaagagt acaactctaa aagaaatata
    15601 cctagtgaga tacgcagatg attttaaaat tttctgtaga aattataatg aagcgaaaaa
    15661 agttttctat gcaactaaaa tgtggttaca ggagcgtcta aagttaccaa tatctgaaga
    15721 aaagtcaaaa atcacaaatc tttcaaaaga agaaagtgaa tttttaggct ttacgatgaa
    15781 attagtgacc aaaggtaaca aaaaggttgt taatacgcat ataggtacaa aagcacaaag
    15841 catgattaaa gtgaaactaa aaaaacaaat caaacgaatt caaaaaagtc ctaatagcaa
    15901 agataccttt atctatattg gagtctataa cagtatggtt attgggattc ataattactt
    15961 caaaattgcg actcattgta gtgtagcaat gcgaaaaatt gcaagagaac tcagaccaag
    16021 ttttgaaata cgactacgag aacaaggaat ctcaaaagaa ggacaatacg gaaagtacga
    16081 aggatacaag ccttacctac ggtcaggaca aatacgatat ataagagggt ttccaatatt
    16141 accagtaggg tatattcaac acagacatcc gatgtgtaaa aaaagaaata ttaataaata
    16201 caccgaagaa ggtagggaag ccattcataa gaagcaacaa accgtagaag aatggaagat
    16261 atcgtggttg tgtagcaatc cagtgcttag taagagagca acgattgaat ttgcggacaa
    16321 tcgaatttca aaattcatcg ctcaaaaggg aagatgtgca gtaacaggtg aggagcttat
    16381 cttatctgaa atgcattgtc atcatattat cccttatcat gaaagcaaaa gtgatagcta
    16441 tgaaaaccta gtgattgtta ctgaggaggt tcatcgggta atacacgcta cacaaagtga
    16501 aacgattgag gaacttctaa aatatctaaa attaaatcca aaacaaaaag aaaaactcaa
    16561 tgagttgaga ttaaaagttg gtaacgaaga aatatcttaa taaatatttg taggacggga
    16621 aaacagaatg tcttttatag acgagggaac gccgtatgcg gtgaaagtcg cacgtacggt
    16681 gtggactggg ggaaaagacg gagataatat caaactctta cctatcagta tcgattaatc
    16741 cagattttat tgaaacggta aattatgtca caaactttca acgagaaatg cgtaaagtag
    16801 aagcaatgac tgttttagct acacaatccc cacaagaaat ggtgccagaa aatatgtctt
    16861 ctgataactt ctcgaaactg aagaaagtct ttgaattttc ttctacgaag atctttatgc
    16921 gtatggatga atctatttta cgtcatatag aaggattagt gggtaaatca atgacgaact
    16981 cagaattaga atccattcct caacaaaatc aaggagacgc tgtgatcaat tttggctcaa
    17041 aagaaaccat tcgtgttcat tttagtccga acaaacgtca attaaaattg tttgatggag
    17101 gaaaataatg gaaaaccaaa atgaaagttt aatcaagcag tatgttaagc gtcgtgcaaa
    17161 gcggcgctta tttttgtggt tgtttggtac ttctgcaggt ttgattacta ttttgatcac
    17221 tgtgttcgtg accctatttc taatacttgc ggcgggctcg attgataatt cggattcaga
    17281 ttcaagcagt ggtggcgaag cttttacagg agaatattcg gaaggcttac cgatttataa
    17341 agaaatcaaa ggaagaggcc ctttttctga tgagattgcg caatatgccg taggtgcagc
    17401 agtgaaatat aaattattac caagtgtgat cctttcgcaa tacggttacg aatcagcgtt
    17461 tggtacatcg gcgtccgcaa gaaatgatct caactatttt gggattactt ggtttgatgg
    17521 ttgtctgttt cctaaaggaa ctgcacgagg aattggtggc attgaaggtg gctggtacat
    17581 gaagtttccc aactcaaaag ctgcattttc ctattacggc tttatggtag ccacacaatc
    17641 caattttaat gcttgtgtag gaaataaaag ccctggcgca agcttattga tcttaggacg
    17701 aggcggttat gccgctgcag gaattacgga agatagtccg tattatacag gttgtatgtc
    17761 aattatcact tctaataaat taaccgaata tgatgaattc gccatcaaac attggggtga
    17821 aggtggcaat aacaacggca cgattactgg tgaatggacg aatccattcc ctggcagcag
    17881 tttagataaa agttccttca gcggtggtca attatttgga acgaatccag gcggtgaatt
    17941 ccgtccgaac ggcttccatg atggattaga ttttggttca gttgatcatc caggaagtga
    18001 gattcatgcg gttcatggcg gaaaagtcgt gtacgttggc aatcctggta tttcaggttt
    18061 gggcgcgtgt gtgatcgtga ttaattacga tggcttgaat atggtgtatc aagaatttgc
    18121 aaatagtaca ggaaattctc gagtgaaagt aggcgatcaa gtgaaagttg gtcaagtaat
    18181 tgggatacga gatacagcac acttgcattt aggatttact cgaatggatt ggcgtcaagc
    18241 acaaggacat gcattcattg atgatggtac atggatcgat ccgttaccat ttttgaatag
    18301 cagtaaaaaa tagatcagga gaaaaaatat ggaaaataaa acgttaaaaa tcgtcttaac
    18361 agctgcaatt agcgttagtt taatcggcaa tattgcgttg ttttggcagc tgaaagagga
    18421 acaagcagca aatacctata aaattgaaga agtggctaaa aacgcgtctg agaagctcaa
    18481 aaaaaattcc tctgaggcac aggcgaagat cgacaagtta aatcaaacca tcaatgagaa
    18541 aaaccaagaa atcgatcagc tgaagcaaca agatggcaca aaagcaaaag aggaagtaac
    18601 tgaagcacaa agaaagacgg cagaagagtt cggtcaattg gccattgata aatcattaag
    18661 cagaaatgaa ttaacggaaa aactaaaaga tgtcgcaacc caagaagtga tcgacaaatt
    18721 aagtcctaca gacgatgatc accaacatga tgattacgga agttactcct ttacattagg
    18781 tgacgtgcaa acttacgctc aaacaagcag tgtaaaagag gaacaaaatt ttgtcgtatt
    18841 tgttgattat acaatcggca atccgcaatt caaagatgtc aaaccacaaa aaataaaagg
    18901 tggattaact gtcactgaaa aacaagtaga tggtcaatgg aaagtcatag actttagtta
    18961 tttcactcgt taggaggaag aaaatgagta agaaaaaagg agaaagacaa cgtttcaaaa
    19021 aacgaaaaag ttatcttaga tggctgggaa tctttatgat tctcggcttt ttgattcttg
    19081 ctagtccgat ttatacgaat cagaaggtag atataccaga tgaggtaagc acgaacgcct
    19141 ttttaaacac gaaagagctg acaatggttt caaaagaaaa aggagcgaac cagcaattag
    19201 tttttgaatt tgcgatcgat gatgaagatc aaagcttgtt aaaagaactg gctaatctta
    19261 attatcgcgt agaagtaaag acagctaaag gggattatca agcaatacga gccaaagtga
    19321 ttaaggtgtc tgatgattat tttgcagtga agctaacgca tgtaccagaa gaatatatcg
    19381 ccatgcgttt aaccattatt cctgaaaaaa ttgatccaaa agtggatatg caagaaccac
    19441 aagatctgat ttattacgtg cacgaagata aggttaaaga tcaagtgaaa gatgaagatt
    19501 atgaacaaca cgcgatcaat tacaaagtga aaggatacaa gaaagaacaa aaagcagctc
    19561 aaaaacaaat ggaatctttc caagcaacca ttgatttgaa tgaagaatta gtgaagaagc
    19621 taaaagatca attgccttat caagtcgcag atgatcagga aaatactgaa aacaagatta
    19681 atagctacca gcaagaaatt gaaacatcga aaacgcaact gaaagatcaa gaagagatca
    19741 ttcaaaaact tcaagaaaaa attgatcgta tgacaaaaga aaagatttag aaggacaggt
    19801 ggagtgaaaa aatgaagcga acaaacttgg ctgacaaaga tactttcgct gagcagaaag
    19861 tattgattaa agcctatctc aaagttgtaa aagctaaaga aatatgtcga gaagtgaatt
    19921 tatctaacac aacaatatct gagttgaaga atggtcgaaa gaatttagat actttaaaat
    19981 tcagatcatt tgaagctcta tatgtagctg ctaaaaaata ttttacagct gataacaaat
    20041 aaaaaacagg agtattttat gtgaaaaaag tatataaaaa atgcttatga atcagctata
    20101 tcaccttaac catttgttaa tgagatggga gaaaacatta accacgattc taacgcaaac
    20161 atcaagcaca taaaacattt aacactcctc ctttctggct gaagatttca accaaacagg
    20221 aagacagcgt atcaattata gcatacactt tttcttaaat tcatttttca tatgacaaaa
    20281 tatttccttc taatcgacaa agttagaagg attttttatt gtctaaatac acaaataacc
    20341 ttaattttta aagagcataa ggaaacgtga tatcactttc tcacgaaagg tgttaggtag
    20401 gctgtgccta ccacgtttct aagaaagata aatgatatca aaattttgga tttgtgtgta
    20461 gatttgtggg taggatgaaa gcgaatgtgg gcagtaaaat aagcgtttgt gtgtagcaaa
    20521 atcaaaaaat gtgtagggat atgtgtagct acacatatcc ctacacataa taaatttgga
    20581 ggaaaatatg gacttattaa ttagaaatat tgaagaaaag tatattaata aaattgacaa
    20641 acgttgtgaa gaacttacgg tcaagactgg caaaaaatgg agtcgaaatc aatacctaaa
    20701 agttttgatc gaaaatgatt ttgatcacgc tcttctgaat tataaaaaag accaatttga
    20761 tcggttgtta gaaaaatttg tggatattca aacttataat acgaaaactt tagaagaata
    20821 tattgcaaca aataatcaat taattggttt gttaattgaa taataaaaat agtattgtga
    20881 atttataaaa ggaggaaatc aattttggca aaagcaacaa gaaaacatgt atatctttac
    20941 gatatgcata tcgaagtact tgatgaaata atttctactc atgaagatat atctaattat
    21001 agtgaagcag tcagacattt gtgtatgatg tatgatccaa aaatcgaaga aaaaataaat
    21061 ccaattcaaa ttaaattgaa tgcaatggga aaagaaattt ctattttaac cgaaatggtt
    21121 tcagagtttg cggatcttca tttgaaagat acaggaatac taattggtac aaattcaact
    21181 gtttatcaag aagcagaaga acgtgtggaa ggaaaaatta aatccaatca aaccaaaaaa
    21241 tattcttcta agttaaagaa accagtgaat gaatctgttc ataccagagt agatccattt
    21301 gatccaacga agattctaaa aagataaaag tagaaggaga acgtgatgaa taaatcgcct
    21361 gcagttattc ttacttgtca atttaccttg cccaataaaa aatctttttc aacatacatt
    21421 gattatatga caagagaaaa agcactggaa gaaatggaac gacgtacgcc cgaagaagaa
    21481 caggaactgc aacgaatcaa gaatgcttta gaggattttt atattcctga aggagaaact
    21541 ttttcggaaa gtaagacgga taaagaattc agtgaaacgt cgaatgaagc tcaatcgttg
    21601 atggaacatg gaatcaattt tgacaagtta gaggaacaag attttaccaa atatctttct
    21661 tatatgaccc gtcactatgc gttagaacaa aagaaagaac tgacgcaaag ggaacaaaaa
    21721 gaataccaac ggttgaacca agcaatgaaa aaatatcaaa cagagccaca taaaaaagct
    21781 tcaggaaatc ttcctggagt tttttctatg gcttcagacg aagtgaaagg aagtgatctg
    21841 aaggagatca aacaaatctt ccaaagagga caacaaaaag gctcaatcat ttatcaagat
    21901 gttatctctc acgacaattc gtatcttgaa aaaatgggct tgtacgatcc caaaacagat
    21961 accttagatg aagaaggttt gaaagcagct ggaagaaaaa tgatggagac attattcgag
    22021 aaagaacaat tgaatgaaac aggttactgg atggcaacga ttcaccgtaa cactaagcat
    22081 atccatattc attttgcagt tgttgaaaaa gaaaatacgc gtaaaccgta tactgagatt
    22141 gaaaatggtg tgagttatat cgtaccgaag gggaagagaa gacaagcaac attagacgca
    22201 atgaaaacca attatgtaca tgagttagaa cgtttctctt atgaaaagga tcgaatgatc
    22261 ggtatggaga aacgaaattt attgacacga aaaagtgatt tgcgtaacac cttaacaaaa
    22321 gtagtaaaag aaccagcacg ttacgatcga cacgccatga acttattaaa tgaagtatat
    22381 aaaaccctac ctgaaaaacg ttcggaatgg aattatggag atgaaaatcg aaccaagctt
    22441 tcaccattta caaggggaaa acttgatgag ttaaccaaat atgttttaac aaaagaacct
    22501 ggatatcaag aatatataca gatttcaaaa gcattgaaag aagaagccaa aagcctttat
    22561 ggggaaagca aaagagaaac aaagaatgca gaaaaaaacg ccctctttga tttaaaaaag
    22621 cgcacaggaa atgcgatttt aacagaactg aagagacagg atagtcaaat aaaaccatta
    22681 atagaaagtg tcaatcagat gcaatctatt tacaatgaac gatcctttcg aacactcaaa
    22741 cagttgccaa caaatgaata caagtatagt tatcaagaat tcgtaaagcg taggaaacaa
    22801 ttccaacaaa gagttgtcac gcagcgaagc ttgcgtcaat taaatcgaac aattaatgca
    22861 catgaagaaa aataccacgc aagtaaagca tatgaagagc aacagcgaag aatccaaatg
    22921 gaacaagaaa gacaatagga ggaagagaaa tgaaacaata tttagatcaa tggaaagtca
    22981 tagaaggatc actaaaagaa gaacgaatcg aacaacttcc tgattgttta gaaaaagagc
    23041 atttgtttca gataagcgaa atgttgagaa acgaacagtt tgatccaaat caatttttag
    23101 ttgttgagta cccagctact ggtgtgtatt gttgtaatca tgtgaagggt gaaaaatatt
    23161 ttattattca agaatacgaa ggtaagttag cgccttatta tactacttgg gaaataaatg
    23221 aagagggaat caataatttc ccatgtgaaa gcattgaaga gtctatttct ctcacggaat
    23281 gttaaataaa tagagacgta aaagagtcct gaacgtgatt gtccaggact ctttttcaat
    23341 gaattgtttt ccgccaattc actgagtggt gcgattcaat tttattatat caaaagaaag
    23401 tgagattcca aagtgaaggg aggaagaaga aatgactcag acaacgattg gtgttgtggt
    23461 tgaaaaaagc agggataatc tcgtttttgt gacagaaatt caaacaggta gagcttttgt
    23521 agtcacagac aaagctgcaa aagcgtatca aaatggcaat attttaacgt taaatctgac
    23581 tacgaagatg ttcgttgatg cagtagaaaa ttatccattt gtttagacaa acgatatttt
    23641 acaaggagga aacggacatg gcagaagaaa aagaaccact agataatagt cggttgggaa
    23701 agtccaaaag aaaattagta cggttgcaaa acgaattaaa taatcaattt caaaagctat
    23761 ttgatcacca aaaattgaca aatgggcaac caatgaatga caaacgaaat ggtcgttcat
    23821 ggtttaacca gcaagaaaaa atagaaaata aaatacaaag tttgagagaa gagatcaagc
    23881 aacaagaaaa acaggtagaa aaacttgaaa gacaagaaga gctaaaggaa atgggctata
    23941 acaagtacgg cggactggat atgacgatcg ataatattcc aagaatcaaa gaagaaatcg
    24001 aacgctttga aaaaggtgaa tcgacttttt cagccgccac gatccgaaaa tatcaacgga
    24061 agttggaaac attagaacag ctgaaagaaa aatcagaaaa aggaaaagaa aatatcctcc
    24121 ctgaagtaca agcgatcatt gacagcggac gagtgacgca atggaaaaaa aatccaacca
    24181 tttatttttt gaaaggctat cgaaaagttg ctttagaact gaatgaaaac gggggatttg
    24241 aggaatcaaa aaaataccaa gccacgtcgg aagaggaaaa agcagctgtt cgtgaattac
    24301 ttgaagaggc tgcaccaact gattctctga aggagaaaga aaaagatcat ttctatcgag
    24361 tagaattcaa cgaaaatgat ccagaaaaag gattgaaaag ttatggtggg gagatcgtaa
    24421 cattagaatt gatcgatcaa cttaaaacgt tggataacca atacgctgca gaagcaggtt
    24481 attataaatt ctattttgaa gaagtgaaga acggagaagt agtagatcag atccgaatgg
    24541 atctagggga tggcgtcaac agtaatcacc ccatctattt agagttagca aaattgtgcg
    24601 aacaagtacc tgagaaggaa caaaaacaat cggtcaaaaa tgaacctgtt tcgaaagaac
    24661 aaatgcagtc gaaagaaaca aaaacaaaac aaaagggcta tcaaaaacga acggcagaag
    24721 agatcaaaca agaagttaaa tccctttcgc aacaggcact ggatgcggtg aaaaagcata
    24781 cccattcttc tgaagacgtc aaagaacttt tgaactttat gtctcgtttt ccagaacgat
    24841 cctttagaaa tcaattattg attgaggaac aatttccagg tgcaacggct tgtttaggtc
    24901 gtgccgcgtt gaaaaaagaa ggaatctata tcaaaaaagg ggaacaaggg aacaagatct
    24961 ttgtcagaaa aacggtcaaa ggattttatg agaaaggacg tggctttgtt cgagaaacag
    25021 aagctacacc agaagataaa aaacgaatcg aaagtggtca aatcgaagtg atcaaaaaa
//
LOCUS       DAFELK010000043        24816 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFELK010000043
VERSION     DAFELK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.044"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            1..794
                     /locus_tag="LP433_001984"
                     /pseudo
     CDS             1..794
                     /locus_tag="LP433_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
     gene            934..1860
                     /gene="cysK"
                     /locus_tag="LP433_001985"
     CDS             934..1860
                     /gene="cysK"
                     /locus_tag="LP433_001985"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBL2006126.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2096..2542
                     /locus_tag="LP433_001986"
     CDS             2096..2542
                     /locus_tag="LP433_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL2006127.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2814..4166
                     /locus_tag="LP433_001987"
     CDS             2814..4166
                     /locus_tag="LP433_001987"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBL2006128.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            4337..4624
                     /locus_tag="LP433_001988"
     CDS             4337..4624
                     /locus_tag="LP433_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006129.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4850..5293
                     /locus_tag="LP433_001989"
     CDS             4850..5293
                     /locus_tag="LP433_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2006130.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5299..6483)
                     /locus_tag="LP433_001990"
     CDS             complement(5299..6483)
                     /locus_tag="LP433_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBL2006131.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6751..7449
                     /locus_tag="LP433_001991"
     CDS             6751..7449
                     /locus_tag="LP433_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL2006132.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7456..8133
                     /gene="nth"
                     /locus_tag="LP433_001992"
     CDS             7456..8133
                     /gene="nth"
                     /locus_tag="LP433_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBL2006133.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8259..8792)
                     /locus_tag="LP433_001993"
     CDS             complement(8259..8792)
                     /locus_tag="LP433_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006134.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9089..11470)
                     /locus_tag="LP433_001994"
     CDS             complement(9089..11470)
                     /locus_tag="LP433_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL2006135.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11460..12107)
                     /gene="recU"
                     /locus_tag="LP433_001995"
     CDS             complement(11460..12107)
                     /gene="recU"
                     /locus_tag="LP433_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBL2006136.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12171..12710
                     /locus_tag="LP433_001996"
     CDS             12171..12710
                     /locus_tag="LP433_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBL2006137.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12800..13219
                     /gene="gpsB"
                     /locus_tag="LP433_001997"
     CDS             12800..13219
                     /gene="gpsB"
                     /locus_tag="LP433_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBL2006138.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13241..13608
                     /gene="rnpB"
                     /locus_tag="LP433_001998"
     ncRNA           13241..13608
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LP433_001998"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13817..14983
                     /locus_tag="LP433_001999"
     CDS             13817..14983
                     /locus_tag="LP433_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBL2006139.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15029..16525
                     /locus_tag="LP433_002000"
     CDS             15029..16525
                     /locus_tag="LP433_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBL2006140.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16606..17289
                     /locus_tag="LP433_002001"
     CDS             16606..17289
                     /locus_tag="LP433_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2006141.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            17934..19124
                     /locus_tag="LP433_002002"
     CDS             17934..19124
                     /locus_tag="LP433_002002"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBL2006142.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19226..20179
                     /locus_tag="LP433_002003"
     CDS             19226..20179
                     /locus_tag="LP433_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBL2006143.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20248..21597
                     /locus_tag="LP433_002004"
     CDS             20248..21597
                     /locus_tag="LP433_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2006144.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21780..22103)
                     /locus_tag="LP433_002005"
     CDS             complement(21780..22103)
                     /locus_tag="LP433_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006145.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22232..23395
                     /locus_tag="LP433_002006"
     CDS             22232..23395
                     /locus_tag="LP433_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL2006146.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23465..24814
                     /locus_tag="LP433_002007"
     CDS             23465..24814
                     /locus_tag="LP433_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL2006147.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
BASE COUNT         8285 a         4260 c         5177 g         7094 t
ORIGIN      
        1 ggaacgagtc ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca
       61 gatgaacaag gatctcaaac agttgctgat cctcaagcgt ttatcgatca aatcggctgg
      121 tctgcgtcag aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg
      181 ttgttggaaa gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc
      241 ggtgtgaaag gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaacg
      301 gacaatgggt aacgatgaat gaaccattcc gaaaatattc ttcttattgg gaatccttcc
      361 aagaccatgc gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg
      421 gcgtgtggaa aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt
      481 atgctaccga tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa
      541 cccgttttga tacgccatca acaggttcgg ctaccacaag tacaacaaca acgactacta
      601 cgacgacttc aacgtcatca tcttcaacaa cagatgtaaa tacaaataat ggtcagacat
      661 atacagtcgt gtcaggtgat acgctatggg atattgcaca aaaatttggc atgtctgttg
      721 atgatctaat ggcgaaaaat ggcatgtcta tgtccagtta ttctttatta gttggtcaag
      781 aactaaacgt ttgatttaga taaaaaggca aagaaactac catatatggt atatctttgt
      841 cttttttttg ctagtcaaag acgaatcact cgccataaat gaacagattg tattatgata
      901 agtaagaaga gcaaagacaa ggaggaattg aagatgacag ctatctataa ctcagtcacc
      961 gaattgattg gcaaaacgcc aatcgtcaaa ttaaataaaa tcgtaccaga agattcagca
     1021 gatgtttttg taaagcttga gttttttaat ccaggaggaa gtgtaaaaga tcgtattgct
     1081 ttaagtatga tagaaaaagc agaacacgat ggtctactga aaccaggtga tactatcatt
     1141 gaacctactt ctggaaatac aggaatcgga ttgtcgatgg taggagttgc aaaaggatat
     1201 aaagtaatca tcgtgatgcc tgagacgatg agtatcgaaa gacgtttatt gatgaaaggg
     1261 tacggcgcag agttgatttt gactcctggt gcggatggta tttctggatc aatcagagaa
     1321 gcagaacgtt tggcaaaaga aaacggctac tttttaccat tacaatttga aaatgaagca
     1381 aatcctcttg tgcatgagaa gacgactggt cctgagatac atcaagcatt tggagtaaat
     1441 ggcttggacg cgtttgttgc aggtatcggt acaggaggaa cgatcactgg cgctggccga
     1501 gaattaaaac gtgtgtatcc gaaaatcgaa ttaatcgggg tagaaccagc agaatctgct
     1561 attttagaag ggaaagaagc gggacctcac aaaatccaag gaatcggtac aggttttgtt
     1621 cctaaaacac tggatacttc tgtgtatgat aaagtccttt ctattagtgg agacgaagcg
     1681 atggaaacag ctagagaagt tgggcgaaaa gaagggattt tagtaggcat ctcatctggc
     1741 gctgcaattg ctgccgcgct aaaagtcgca aaagaattag gaaaaggcaa gaaggtatta
     1801 gctgtggttc ccgacaatgg tgaacgttat ttatctacag ccctttacca agagatataa
     1861 ggcacttggt ttttctccag ataggtttat gtaaaaaact tttaaagatg aaaagaacac
     1921 acaaaaattt atgatgagaa aaattatttg aatagagacg taaaatagtg aacgcgactg
     1981 ttttacgtct tttttcatta aaatacaata aaattgaatt ttcttttcat gttaagtgga
     2041 ttttaaaatg taaaaatagt atgataagac gagaataaca acgtggggtg tttacatgga
     2101 aaataagtta gtcgaagagg ttatcgaaaa gttaaaaaaa gagaacattc gaatcacacc
     2161 tcaacggtac gcggttttag aatatttgat tgaacatcat tcccatccaa cggctgatga
     2221 gatttataaa gcacttgaac atcggtttcc aaatatgagt gttgcgactg tttacaataa
     2281 ccttcgctta tttacttcga ttggatttgt tcaagaaatg aagtacggcg atgcttctag
     2341 ccgatttgat ttcagttcaa agcgtcatta tcatgtaatt tgtgaaaact gcggtaagat
     2401 tgttgatttt cattacccag ggcttgaaga tatagaaatg gctgcgagca gactgactga
     2461 ttttgagatt aatgaacatc ggttggaatt gtatggactc tgtccggatt gtaaagagtc
     2521 agcaaaaaag gcgcaaatgt aaaaacagtt tctataagtg ttatacctaa aaaaagctag
     2581 ctgtgtaaaa aaacgctagc ttttttattt ttttgtcttt tattcacaat cttagatatc
     2641 aaagtgaata ttatcacaat aagaatcttg tagatattgg gttcttatgc ttgaaaagga
     2701 atgaaactac aaacaaacct ttgtgaattc acaagcatta aactgttgta tccgttttat
     2761 ttctgttata gtagttttgt cgaaggacaa aatgttaatc ggagggacca taaatgaaag
     2821 tagtagtaat tggctgtact catgcaggta ctgcagctgt aaaaagtatt ttaaaaaatc
     2881 atccagaagc agaagtgaca gtatatgaaa gaaatgacaa tatttctttc ttatcttgcg
     2941 gtatcgcact ttatgtcggc ggagtagtaa aggacccagc aggcttgttc tactcaaatc
     3001 ctgaagaatt atcttcatta ggagcaacag ttaaaatgga acacgatgta acagacgtcg
     3061 atacagaaaa taaaacagta acggcaaaag atctgaaaac aggagaaaca gaaacggttt
     3121 cttatgataa attagtgatg acaactggtt catggcctat tatcccaccg attagtggaa
     3181 tcgatgcgaa aaatgtactc ctatgcaaaa actacaatca agcaaatgaa attattgcac
     3241 aagcgaaaga agcaaaacgt gtagtaattg ttggtggtgg atatatcggt attgaattag
     3301 tagaagcttt tgtcgaatct ggaaaacaag tgacattgat tgatggatta gatcgcatct
     3361 tgaataaata tctagataaa ccattcacag atatcttaga aaaagaattg acagaccgcg
     3421 gtgttactct tgcgctaggc gaaaatgtta ctgaatttat cacagatgaa gaaggaaaag
     3481 tgaaacaagt agctacacca acagatacat ttgatacaga tatggtcatt ttatgtgtgg
     3541 gcttccgtcc aaatacaaaa ctgatcgaag gaaaagtaga tacactgcca aacggggcaa
     3601 tcaaagtgaa tgaatacatg cagacaagtg atccagacat ttttgcagct ggagactctg
     3661 cagtagtcaa ctacaatcca agtggcacgc aaaactatat tcctttggca acaaatgccg
     3721 ttcgtcaagg tttacttgtg ggaaataact tgacagatca taaaatggcg tatcgtggta
     3781 ctcaaggaac ttcaggactt tacctatttg gctggacgat cggttcgaca ggtgtgacca
     3841 aagaaagcgc aactttgaac gatctagaag tccaagcgac tgtatttgaa gataattatc
     3901 gtccagagtt catgccaact actgaaaaag taatgatgga gctagtctat gaaaaaggaa
     3961 cgaatcgtat cgtaggtgct cagttcatgt ccaaatacga cattacacaa tcagcaaata
     4021 ccatgtcttt agctgttcaa aataaaatga ctgtagaaga tctcgcactt tcagatttct
     4081 tcttccaacc acattttgac cgcccatgga attacttgaa cctacttgca caagaagcgc
     4141 taggcgaaat cgaaactgca caataaagaa aaagggttgt gacacaattt tgtcacgacc
     4201 ctctgtcttt ttttgtgaaa agtacaatta gttgtctttc ttcgaatttt ttgtcacaat
     4261 aagcagcaaa gataaagctg ttacataaaa gaacaagcag ctttatttga ttttgaaaag
     4321 aaaggtgaga aagaagatga ataaagaata ttttgtccaa caagatgcat ttttagaaga
     4381 ttataaaagt gcttcgaaga aattaacgat caatattgat gagttggcag atcaagtact
     4441 ctctcagttg aatgaaacgc aagaggaata ttacacgatg ccagcaaatg acgccaaaga
     4501 taatgtttct catcgttttc ctttcagtag acgcatctac tcagatgaaa atgacggcac
     4561 attgaataca gagtacacat atgaaggtca gccatatgtg ctagaaactg atgatgatct
     4621 ttaaagacag tttttgaaaa ggccgctcat ccttaagtga tgacaaaaaa tcatcacaat
     4681 taccgatgac tgtctcttta ctatctttta atcagaaaaa ggggttatga caagctttgt
     4741 caaccccttt ttttcttggt ttcagattgg gttttcctac aaaatatttt tatctttgtt
     4801 gaataggaaa caaaaaaaca atataatgaa agaaaaagaa ggtgtagaaa tggataaaag
     4861 acaactgcta atagaagaat atctggattt agctaatgag attattcatc gtaataaacc
     4921 agaaatggaa aaagaatttg caggatttac tctaaatgaa ctagaagtga ttgaacatat
     4981 cgggaaaatc cctgatccta acgtgacaaa attagcgaat gctagttaca tgactagagg
     5041 agccatcagt aagctaacaa aaaaactgat agctagaggg atcataaaca cttatcaaag
     5101 cgaagagaat aaaaaagaaa tctattttca attgacgcca atcggacaaa aaataaggaa
     5161 tagacacgag caactccatc aaaaatgggt acagcgagat gctactgtat ttgaaaatat
     5221 gtcaaaagaa gaatttgaca cagtatttcg ttttatcggt cgatacagag aatttatacg
     5281 aagtagcaaa tgaagctact attttttatt gtagtgataa taggcaaaaa tcataagcaa
     5341 aaatccgaat accgtcggaa gaaatggtgc tgcagcataa agctgtcctg cgattagcgg
     5401 gccgatgacg cgcgatagag attgtatact ttgggtaccg cccattacaa gaccttgctg
     5461 gttatctgag acagaattgg atagttggcc attgaataca ggagtaaaaa tagaatcacc
     5521 gaaaccataa cagataatcc caaataaaaa caaaatcggc agtagaagaa ttccagataa
     5581 tgtgatgaat agataggcga ggatttcact gaacatccct attcttgtga tctgctgttc
     5641 tgaaaatttt ttgagcaatc gaggcataat gaacaattgc gagacagtat ccaagattcc
     5701 aatcaaagag aagcttaaac caaccaaccc agccttccac tgaaaggcgt caatcgaaaa
     5761 ttgagaaaag atagattgaa gagagccagc tgccaaccaa acagcaaaac ctgctgtcaa
     5821 taaaggaata acggatgaaa tcttgaataa ttgttgtaat tggtgaaaag gtcttacatg
     5881 ggagaaactt aaatctactg aacgtttttt tattggaagg ctttctagca taaatgtgta
     5941 gccataaacg gcatttaaga aagtaaagag tgctccaata aatataggaa cagaattccc
     6001 caactcagct aatagacccc ctataatagg acccagcgtt gttcctatac cgactaaagc
     6061 acccatccat ccaaaaactt tggttctttc attaggttcc gtgatgtcgg caaagtaagc
     6121 atataaggtg gagatttctc ctgccgtcaa tccttcaatg atacgaccaa ggaacaacat
     6181 ccatatcgaa tttcctaaac caaaaagcaa atatccgata cttgatccta ataaactgat
     6241 aataaggatc ggatgacgcc caaaatgatc acttaagcta ccgagaatgg gggcagataa
     6301 gaaggcagct agagcataaa cagacatgag caaagtgata tagaaagctt gctgatgtat
     6361 ggagtgagaa taaggcagcg ttaaaaacgg aagtacagga ctgacgatag taaatcctaa
     6421 tccagtgaat aagacagaga cgtatccaaa aactttagaa tgtttatttg tgaaactgta
     6481 catgtaaaaa ctcctttatg caataatgtt aacttggaaa caaaaatagt gtatagtaat
     6541 tttgtttcct tgtcaacatt ctaaggaaca gcgaaatcta cttaatttat ttattccgaa
     6601 aagtgaagat acgcatcaaa aacatgaaca aacaaaaatc aagtagacga cattgtaaat
     6661 ctgaccgatc agtgaagtaa atagaaaaga aacctgttct tgcttcccat gtttttttta
     6721 cgtatactgt gattgagcgg aggagaaatc atgttgaatt tagaaaatta cttaagcgct
     6781 ggacaaacag tcatatctaa tcttttactt aaaaattatc ataggatcgg tctacaatct
     6841 gaagaatttt tatttgttct acagttgcat atggcacagc ttgaaggaga tactttccct
     6901 gatttgcaga tgattgctat ggatatggga atcaaacaag atcagatttt tcaaatactg
     6961 gatcgtctcg taacaaatgg atttatcaag atagaaacga cgattgtcaa cggtaaaaaa
     7021 gcagatcgat ataatcttta ccccatctat gatctattag gtgagtattt aaaaacacaa
     7081 gaaaaaaaat acgaagaaaa aacacaagaa aaagaaatcc agtcagtgta tcaattattt
     7141 gaacaagaat ttggacgccc gctttcttcg atcgagttcc agcggatcgg acaatggcta
     7201 gaagaagacc attatcagcc ggaaattttg aagctagcac tgcgggaagc cgtattaaat
     7261 caggcttata gttttaatta cgttgaccgc attttgctat cgtgggaaag aaaaaatcta
     7321 cgtacaaaac aacaagtgga agaagaccaa aaacgaagaa aacagcagct tcttcaaaga
     7381 gaagtagaac agtcagctca acaagaagaa ttgccgaaag tctcactgaa aaattggttg
     7441 gaggagtagc ggaatatgtt aagcaaacaa aaaacaatgg aagctctaga aacgatgtat
     7501 ggaatgtttc ccgaagcaca tggagaactc aagcacaata atccatttga gttattgatt
     7561 gcagtgatct taagtgccca ggcgacagat gtatcagtga ataaagcaac gccagatttg
     7621 tttgcctctt ttccgacacc cgatgcgtta gcagaagctt caatcgatga aatcattctt
     7681 aaaataaaaa cgattggttt gtatcgaaat aaagcaaaaa acatcaaagc gtgtgcacag
     7741 cagctgattg aacgtttcga tgggcaagtg ccaacgtcaa gagaagaatt gatgtctctt
     7801 cctggtgtag gcagaaagac agcaaatgtc gtattggggg atgcattcgg gataccagca
     7861 atcgcagtag atacccacgt ggaacgtgtc tcaaaacgcc tgaggatctg caaactagat
     7921 gctacggtca tggaagtaga agaaacactg atgcggaaag taccacaaga attatgggta
     7981 aagacacatc atacactgat tttttttggt agatatcatt gcacggcaag aaatcccaag
     8041 tgcgaggtat gtcctttgct atcaatatgt caagatggga aaaatcggat gcgtctaaaa
     8101 gaaaaggcgc taaaaaagaa accacgcctg tagacgtggt ttctttaatt gcaaataaat
     8161 gtatgaatta tcttgttatt atggagaaaa gctgtttcgt ttatcttttt tgcatgaaaa
     8221 agtaaatgta catactcagt agctaggatg gtaacttatt acaatttatt gcgataaaaa
     8281 taaaagttgt tatttttatt gggaaaatac ccgatgtaga aaataatgcc ttccaatata
     8341 cctataaaat aagtccagta ttccaaagga ttatataaat aagtgacgta tctatctaaa
     8401 ggtgtaataa aaatgataag tgataataaa aaaataccat ttataactaa acataaacta
     8461 atggatttgg gcggtttcag gctcatcaga aaaatataga ttctggtgaa caacaaccat
     8521 aaaaaagtga gaatcattgc atgagagctt ctttccataa attttccttt aagagtagtg
     8581 cttaaaagta cagaaaaaat aataaatgca aggataggag caattaaagt aaatttattt
     8641 aataataaac aaaatttttc agctttttta ttcttggaat aacgaggtat tgttttcgat
     8701 aaaaaaagat ggtgcagaca aattatgata attaagcata ctatcagata actcaaaatg
     8761 aagccttctt tcaaaaaatt attcaaaacc atatattgta ttttttattt gataataaca
     8821 atgggattat taagaagtgg cactaaataa aagactagtg tgtatttagc cgatttaatt
     8881 ataaacaagt aaatggataa agtatatgta atgataaaag aaaaatggat tttctaattt
     8941 ttaagctaaa tgttagatca cacatgtata tgctggatag tcttataaaa aatcatgtaa
     9001 tacagcttgg tacatgattt ttatttgtag ctgtttttta catagacaca aaaaagaaac
     9061 cacgcttgta gacgtggttt cttttttact atctgtttcc agaagctgag gtgctgctgg
     9121 atggtgtatg gtcatttgca gcatccgctc cgctagttgc tggctcactg gaagaagcag
     9181 gaggagcaga tgaagacggt gtcgagcttt cttcggatga agaagaagga accgttgttg
     9241 aagacgctgg ctcgcttgtt tctgctgtcg tgctttcttt tgaggactca gcagttgatt
     9301 cgctttgact agtagagcta gagctttgag tcgttgtctc tgttgttgag cttccaggag
     9361 tctggacata gctggaagat ggaatagttg ttgatggtgt aattgcattc gatctagctg
     9421 tatattgatc tttgtagtac agttcaccgc ccacacgaat taatccgctt ggcatctccc
     9481 agtctgtatt tgtcacgtta gctgaaacat actgcataag ctcgcgataa acatcagagg
     9541 ctacgtgtga cgattctgaa gtgacaggtg tcattttttt attgtaacct gtccacacgg
     9601 aaatcgaata atttggcgta tagcccgcaa ataggatatc tggatacacc ccagaagaaa
     9661 taccaagttt tgcatactcg tcatctgtgt aattggatgt tccggtctta ccggcttgat
     9721 ataacccagc gatttgcgca ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt
     9781 ctgtgatcat ataagctgtt tctggagaca tggctgtttt tccatctggc tcataagttt
     9841 cttctgttcc gtcttggaag acgattttat taacatattg aggtttgtaa taagtccctc
     9901 cattggcgaa agccgcatag gctgctgcca tttttaagga agaagctccg tattttgtcc
     9961 catcttgttc ttccgtatta ctagagatcg cattcgattg atggatcgta ctgtattcga
    10021 tcccaagatt ttttaagaaa gaagccactt tatctgaacc gacttcattg aataatttga
    10081 ctgctggaac attacgggat aagtaaagtg cttggcgtaa agtaatggtg cccatatatt
    10141 gattatccca gtttcctaca ggagtcgaag tcccttcata gttatacggt gcgtcagtaa
    10201 tagtttttcc agtagaatat ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt
    10261 tcatcgtaga accaaaatca cgggaagtat tcactgctaa gttgttgcct aaagttacgt
    10321 cttctgcgat gtgacgtccg ccaatctggg cttttacttt cccggtattg gtgtcgataa
    10381 gggtggaggc aacttgcatc tcgtcgtctg ggtaagagac atactgatcc gtgttgacga
    10441 tatcatatag tttcttttgg gcgtccagat ccaaattcgt ataaatctct aaaccgtctg
    10501 tgtagacatt cttatctgtt ttttcttgta cttcattgat gacttctttg acataattat
    10561 cgacgatctt agtattgtca tcggattgag ttagttcttg cagaccatcc gttaccggta
    10621 cattaacagc ttgatcatat tctgtttgag agattttttc gttttgaagc atcgtataca
    10681 aaacagtatc tcgtcttttc ttcgcctgat ctggataaac ataaggatca taggcggaag
    10741 gggcttgagg catcccagca agcaatgctg tttgcggtaa agaaagttct gataatttct
    10801 taccaaagta catctcagaa gctgtctcca tcccgtacaa gccgtttgac atatacactt
    10861 tatttacgta gtaggtcaag atctcttgtt tcgatttttt ttgttccaat cttacagcca
    10921 tccacgcttc ttgggccttg cgtttcagag tctgatcctc ggcactggtg gagaagaagg
    10981 aaagtttgat caattgctgt gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt
    11041 tagagagggc agaaccgatg atccgaatag ggtcaacccc gatgtgttta taaaaacggc
    11101 gatcttctac cgacacgatc gcatcttcta atgttttcgg taattcattc gcagaaattt
    11161 tttcacgctt ttctgcgcct aaatcttcga atagttcgcc atcttgtgta tatagtttgg
    11221 aagatacggt agcgtctaat tttttatccg tcaattcggg cgcatctttt gcgtaatacc
    11281 agaaaagtcc tacacctgct aaaaagagga tacagaaaaa tgagagtatt cctaaaagga
    11341 tcttgataaa taatcctttt ttatgtgttc cagaggactt tccagaacct ttgccagaat
    11401 tcttcttcac actcttttta ggagtaggct gtttctgtcg tctagagctt ctagtttgtt
    11461 catttgccat tcttgctttc tccttcaata gataatgttg ataaatagaa gtcaaccgcg
    11521 tccaaataag gaatccgcgg agaaatacca gttttgatct ctattcctag ttcttcgatc
    11581 aaagataaag gtagtgattt gcgtcctttt tccttttggg cgtcccagta agcaatcaaa
    11641 tgaacactat tcaaataaaa acagcgcttc aaagacgaaa accataacaa gacaaagcag
    11701 accccatttt gttcgaggca tgctttcata tgttcgattt gatgggcatg gaagttttta
    11761 aagggaaaag atgttttgtt cttggtttct tttgcttcaa agtccaagta aaagcctcga
    11821 tagacgccat tatagtctgt agttgaggct tgggtaaagt aggcttcctt gatcacagca
    11881 gcacttctct taggatagtc tactttcacg atttggatag gggtaggctt tttatggata
    11941 accgccaacc cgcgggaaag ataatattta ttactttcat tgattgcttc ttcaaagcgc
    12001 atcccccgat tgccgaattc agtgatctga tttctttttt cttgaatttt ttcgacggga
    12061 gaggcattct tataataagg ttggccattt ggatagcgca ataccatctt taatcacact
    12121 cctaggccac attatagcaa aaaagcggat agaaagaaaa ggaatctgag atggataagt
    12181 caaaagtaat ctatgtgtct gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg
    12241 atcctaaaat ccaagttgtt aaaaatgttt taaaaaaaga actccatcag ttagcagaag
    12301 aagggctgga atgggtactt gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa
    12361 tagtagcgga attgaaagaa gaatatccgg aactatctct tggtattttg tatccttttt
    12421 ctgattttgg taataactgg aatgaaggga accaagaaaa aaaacaatta gcagaacaat
    12481 tagcagatta tgtcgaagct gttagccatc aaccctacca atcacctagt cagctaaaga
    12541 atcacactcg ttttatactt gagcatacag tgggctgtct gctgatctat gatgaagaat
    12601 tccctggaaa aacgaagtat ttttttgaag atgcacagaa ttaccaagca gatcatccct
    12661 acgaaattcg gctgatcagt atggacgatc ttcaaaattt tagtgaataa tcgatattgt
    12721 gtttgattta tcaacttttt tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat
    12781 gaaaactaga ggtgtaaata tggcgaattt ggtttatagt cctaaagaca ttttacaaca
    12841 agaattcaaa acaaaaatgc gcggctatga tcccgttgaa gttgatgaat tcttagacaa
    12901 tatcatcaaa gattatgaaa cttacagcaa agaactcctt gctttacaag aagaaaacga
    12961 tcgattgagt gcaaaagtag ctcaattatc taaaactcaa ggagcagctc aaacacgcgt
    13021 gcaacaaaca gaggcaccaa agagcgcagc agtgaccaat tttgatatct taaaacgctt
    13081 gtcaaatctt gaacgtgaag tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa
    13141 accagcacaa cctaatccaa ataactacac aaatgcagac acaagcttag atgataatga
    13201 aaaaacacgt caattttaat ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc
    13261 tgacttgatc aggctgagga aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg
    13321 tgcttagcga aaccataagc taaggtactc tttggagtaa cggcaggaaa acaagctaag
    13381 gcttcggcta tgcttaagta tccttgaaag tgccacagtg acgaagcggc tggggaaacc
    13441 catccggtgg aacgcggtaa acccctcgag cgagcaaccc aaacaatggt aggggcgctt
    13501 tttgtctgga agaagaacag gacaaaaagg cagtataact gcagatagat ggttaccgct
    13561 ttgttttttc tccctggaaa agcaaagtac agaacatggc ttatagaaaa ccgcaaacat
    13621 cagggaatta ggtcgtgaca aaagtaatgc gttataagaa acaagaaaaa catttgaaag
    13681 ctatttttca atacttcaga tgaatcgttc ttattacaaa acaaactttt gtatcaccgg
    13741 ttattcggaa tttgagtaaa agtgtggggt aggactgatg tcccacctcc tttttttata
    13801 aataaggaga ttgtgtatgg aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag
    13861 cgggctagaa gcactggttg gtaaagaatt aagagatctt ggaatcgaat gccaagttga
    13921 gaacggacgt gcacgttttg aaggaacaat ggaaacgatc gctacagcta atttatggtt
    13981 acgtacagca gatcgagtaa aaatcgtggt tggggaattc gatgcgtata cgtttgatga
    14041 attgtttgaa aacgtaaaag cattgccttg ggaagatttt cttccactag atgcagcttt
    14101 tcctgtagct ggaaaatcga tcaagtcgaa actatatagc acacctgatt gccaagcgat
    14161 cacaaaaaaa gcaatcgttg aacgtctccg tacctattat caccgtccag cttctgtacc
    14221 actgacggaa actggcgcac attttcagtt ggaagtagct ttgctgaaag accatgtgat
    14281 ggtaactctg gatacgacag gaccaagttt attcaaacgt ggttatcgct tagaaaaagg
    14341 tggagcacca ttgaaagaaa acatggcagc agcacttatt atgttgacaa attggcgaaa
    14401 agaccgtcca ttttatgatc ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt
    14461 aataggccat aatatcgcac caggattcaa tcgtgagttt gcttgcgaat cttgggattg
    14521 gttcagtcaa gaaatcatgg aaaatgttcg atcagcagcc gaagaaaaag cagattatga
    14581 tattgaatta gatattactg gttcagatat caatggacgg atgattgaaa ttgccaaagc
    14641 caatgcagaa gaaatcggat taggctcttc gattaccttt aagcaacaag cagtcaaaga
    14701 cttcaaaacg gataaagaat acggggtcat cgtggctaat ccgccttacg gagaacgtct
    14761 aggagaagaa gaaactgttc ggaaattata taaagaaatg ggcgatgtat tccgtccatt
    14821 aaaaacatgg agtaaatata tcttgactag cgacttagcg tttgaggaat tttacggaca
    14881 aaaagcaacc aaaaaaagaa aattgtacaa tggtgcattg cgtacggatc tattccagta
    14941 ttggggaact cgtccgccta gaaaaaaaga gaaagacgaa taatcttact aattgattca
    15001 ttcaattgga tgtttggagg aatagggaat gaaagaaaaa gagtttttac aagaagtaaa
    15061 agaaatcaat cttctacaac aagctttagg aatcctcgat tgggatacac aaacaggtat
    15121 gcctgaaaaa gctagtgcat accgaagtga agtagacagc tatctttaca gcatttattt
    15181 ttcaaaaaaa atcggtccaa aaatcaaaga agccattcgc tatttttctg aacatccgga
    15241 agaattgtcg gaagttggaa ctgccgtttt tgccaaagta aaagaagagt atgatttgga
    15301 acatcgcgta ccggaagatc ttatgagaaa atatacagct gccgtttctt cagcacacgg
    15361 acaatggcaa aaagctagag aaacacaaca attttctgat tttcaacacg cattgaatca
    15421 aaatattgaa ttaacaaaac agttgatacc ttactggaga aaagatgaaa agacgaatta
    15481 tgatgttttg ctgaatcaat acgaacccgg gatgactgtc gaaatccttg ataaggtatt
    15541 tgatcagctt aaagaaggaa ttctttcgat ccgccgtacg ctccaagaaa aagggactga
    15601 acctgaaaca gactttttaa atcggagaat gacgaaaaaa caacagaaga gatttgtagt
    15661 gaaagtaatc gaacaacttg gttatgattt tagtcgtggt cgtttagatg acactgtcca
    15721 cccatttatg actggaatta atccgaatga tgcacgaatc acgacacgat ggaacgaaac
    15781 agatttcaaa atggctgttt ttggagtgat ccacgaggct ggtcatggta tgtatgaaca
    15841 agacatcgat gataaatatg cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca
    15901 tgaatcacaa tcgttgttta acgagatcat tattggaagt agtcgcagct tctggaaaaa
    15961 gcaatatcct ttctttcaag aatgtgcaga aggaacattc gatgatattc cttttgacaa
    16021 attttatcgt ttattgaacc atacaaaatc aagtttggtt cgtatcgagg cagacagttt
    16081 gacttaccct ctccatatca tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg
    16141 ggtagatgtt gctgaactac ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat
    16201 acgaccaaca aatgatgtgg aaggcatcct acaagacgtt cattggtcag gtgcaagctt
    16261 tggttatttt ccctcttatg cattagggta catgtatgcg gcacaattac ttcattcttt
    16321 gcagcaagaa atagatgtgg aaaatgttct agcgtcagac gattattctc caatcaaaaa
    16381 ctggatgtca gagcatatcc atcaatatgg tgcatctaga aaaccaaatc aattaatcat
    16441 ggatgcaaca catgaaccgc ttaatccgca atacctgatc gactatatga aagacctgta
    16501 ttttaatgta tatcaggtaa aataaaatac aatttacaaa gatagctgaa attcatctaa
    16561 tctatagatg ttttcagcta tttacttaag aaagaagtgg aacgaatgga taaattacaa
    16621 gtgatcgctg attatagtat ggaccaatta gcgcatgatc aaacaggaca tgggagcgat
    16681 cataccaaaa gagttgtcaa gttagctgaa aaaattttgg agacggaacc gcaggcagac
    16741 cgctttgtga cgcttgcagc agcttaccta catgatacga ttgatgataa agtcgttaaa
    16801 aatgagaacg aggcaaagca acagcttcgt gtattccttc gctctttgcc aatagtagag
    16861 gaacagatct cgatgatttt ttccattatc gaaaatatgt ccttttctaa aaatctctct
    16921 gaagcggccg aactatctct ggaaggtaag atcgttcaag acgctgatcg tatcgaagca
    16981 ttaggagcaa tcggcatttt gcgtactgct tatttcggcg gtggacatgg gcacccgatt
    17041 tttgatcctg aactgtatcc gcaaacattc aaggacaaag aaaattaccg aaaaggcacg
    17101 acagtgatca atcattttta tgaaaaactg ttcttgctgt ctgataaaat gaatactgat
    17161 tacggatatg aagaagccaa acgaagagaa accttcatgc gtgaattctt agaagaattt
    17221 tttctggaat ggtctattga cgatgaaaat tttactccag acaattggat caaaaataac
    17281 aaaaaatgat ggaggttgtg acagaagtgg tcagctccaa gatatttcgg atcattttcc
    17341 gtaaaagtta cttctggaac actgtttacc aagaggtcgt gagcctgccg ttcagctccg
    17401 agtcacaagg aacaatttca aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg
    17461 attcggaatt ggcaggagaa caccgtttat tcggaagaat aggactgtga caagactttt
    17521 gtcacagtcc ttttttcgaa ttcaacaagt aaaactttta agaaatattc agagagtaaa
    17581 attaaaaatt gctgataaac gaagatggaa attttatgta tttttattgg tctatgcaat
    17641 aaataaatta aatattcaga atacaattga ttttaacgaa agggcttcta tcaatggttg
    17701 tgttgtattt atctgcccag gtagagtaaa atagatcatt atctaaaagg taattgttca
    17761 tactatataa gtcatttgaa agtaaaaaga tactgtaaat aaaaaatgtg gttaaataat
    17821 tctcataatc agtgtaagcg ttatcaaaaa tatagcatac ttgctttgta gatgaatgac
    17881 acgatatatg tttggtatgt tctgcaagac agatgaatat ggaggtggag acaatgtctt
    17941 ccaaagaact aacaatgtat ttagagaaag aattggatca actgaaagaa aaggggttat
    18001 acaatacgat cgacatacta gaaagtgaaa atggtgcttg tatcatcgta gacggaaaaa
    18061 agatgatcaa tctagcatcc aacaattatc ttggatttgc caatcgcgaa gaattgaaaa
    18121 aagcatgtat tgaagcaacc gaaacttatg gtgtaggagc aggagcagtc cgaacgatca
    18181 atggttcgct gaaaatccat cagcaattag aagaaaaaat cgcagaattc aaagggacag
    18241 aagcagcaat cgcctttcaa tctggattca actgcaatat gggcgctatc tctgcagtaa
    18301 tgacaaaaga agatgctatc ttatcggatg aattaaacca tgcatctatt attgacggtt
    18361 gccgcttatc cggagcaaaa atcatccgaa ttaaacatca agatatgaaa gaccttgaga
    18421 aaaaagcaaa ggaagcgata gaaagtaaga aatataaaaa aatcatgtat atcacagatg
    18481 gtgttttctc catggatgga gacattgcac gattgccgga aattattccg attgttgaaa
    18541 aatatggact gatcacctac gtcgatgatg cgcacggctc aggcgtaact ggaaaaggtg
    18601 caggaaccgt caagcatttt ggattaagcg acaaaatcga tatgcaaatg ggcacgttat
    18661 cgaaagctat aggtgttgtt gggggttatg tagctggatc gaaaacacta atcgactggt
    18721 tgaaagctag aagtcggcca ttcctatttt ctacttcgct aactccaggt gcagctgcag
    18781 ctgcattggc ttcgattact ttgatgcaag aacatccgga acttgtcgaa aaagtttggg
    18841 aaaatgctaa ttattttaaa gaagaattga aaaaagtagg ctataacatc ggtatgtctg
    18901 aaacacctat tactccagtc attttgggag acgaaaaagt gactcagact ttctctaaga
    18961 agctgatcga acatgggatt tatgctaaac caatcgttta tccaactgtg cctcttggga
    19021 caggcaggat cagaaatatg ccgactgcgg aacatacgag ggaaatgctt gatgaagcag
    19081 tagcagttta tcaaaaaata ggaaaagaaa tggaaattat ttaactaaat ttagtttttt
    19141 cgtctattta aaattagaga acatgttcac gcatatattg ttaatcatct gaagatagta
    19201 gtaaaaaaga tcagggagga tcatcatgaa aaaagtattg gtgacaggat gtttaggaca
    19261 aattggttca gagttgatca cacggctacg tcaagaacta ggcagtgaaa atgtcattgc
    19321 gacagatata cgcatgcctg aagtcattga gaaaaacgat atctttgaga tcctagatgt
    19381 aatggattac gaaaaaatgc gcagcatagc agaacaatat caagtggaca cattgattca
    19441 tttggctgct cttttgtcag ctgttgcaga agcaaaacca caattagcct ggaatttgaa
    19501 cgtgactggg ctggtcaatg cattggaagt cgctagagaa ttccagctga aattttttac
    19561 gccaagttca atcggcgcgt ttggtccaaa tactccaaaa gatcataccc cacaagatac
    19621 tcttcagcgt cctacaacca tgtatggggt aacgaaggta gctggagaac tactatgtga
    19681 ttattattat gtgaaatatg gcgtagatac tcgtggtgtc cgtttccctg gattgatttc
    19741 ttatgcaacc ttgccaggag gcggtacgac agactacgca gtcgatattt attattcagc
    19801 aatcaaagaa ggaaagtaca ctagtttcat tgatcaaggt acatcaatgg atatgatgta
    19861 tatgccagat gcgatcgatg ccattataaa actcatgaat gcagatcctg atcgattggt
    19921 tcatcgaaat gccttcaata tatcggcgat gtcttttgac ccggaagaga tcaaagcatc
    19981 tattcaaaaa atcataccag attttgaaat ggattatgat gtggatcctg tacgtcagtc
    20041 aatagcagaa tcttggccaa attcactaga tgtttcttgt gcgcaagagg aatggggctt
    20101 ttcgccgaaa tacgacttag atgtgatgac aaaggatatg ttggaaaaac tgaaagaaaa
    20161 attggtagag acggtataaa acaagaacca catccaaaaa gttttttata cttttgggat
    20221 tggctatggt atgaaagggg acaagggatg gaagaatatc aagccacgcc agtaaaagaa
    20281 gtaaaaatag aaaatgaatt aaaacgtacg atgggatttt ttactgcttt atcgactgtt
    20341 atgggcacag tgatcggtgc aggggtattt tttaaagccg caagcgtagc agaagttaca
    20401 ggatccgcca gtttgcatat gttttcttgg tttctcggtg gtatgatttc tgtctgtgca
    20461 ggactaacag gagctgaact ggcagctgct attccagaaa caggagggat gattaaatat
    20521 atcgaacgga tttacggaaa tacagcagct tttttattgg gctgggcgca agtcgtgatt
    20581 tattttccag caaatgtagc agccttgtcg atcattttcg gtacacagtt cgtcaatcta
    20641 tttggtcttt cccagtcaat gattgttccc gtagctgtta cagctgctgt atcgatcctg
    20701 ttgatcaatt ttttaggttc taaagctgga ggggcttttc agtcgattac gcttgtctgc
    20761 aagcttattc ctttgtttgt gatcgtcatt ttcggtttgt tccgacaaga aggagtagac
    20821 ttccaactgt ttccgatcca agcaggagaa aatctttcat ttttctcagc cttgggagcg
    20881 ggcttgctag caacgatgtt cgcatacgac ggttggatac acgtaggaaa tatttcggga
    20941 gaattgaaaa agccggcgaa agatttgcca aaagcaattt ctttaggaat catcggaatc
    21001 atgatcgttt atttattagt aaatgcggtg ttcttaagaa ccgcatctat cgacggagtc
    21061 gcaggaaaca gcaatgcggc aagtgacgtt gcaaaaatga tttttggcgg cttcggtgga
    21121 agactggtca cagttggtat cttgatttct gtttatggaa ccatcaatgg ctataccctt
    21181 actggaatgc gtctccctta tgttatggca aaagaaaaca acctgccttt tagcaagctc
    21241 tttgctaaac ttcatgataa aactaaagtt cctgtagccg caggtatctt agagctagtc
    21301 atcgctattg gcatgatgat gatcggtggt tttgatacac taacggatat gctgatcttt
    21361 gtcatttgga ttttttatac gatggtcttt gttggtgtca ttcttcttcg taaaaaagaa
    21421 cctgatttgt ttcgaccata caaagttcca atgtatccgt ttattccact agtagcaatc
    21481 attggaggga cttttatcgt atcaagcacg cttatcactc agaccttttt agcttcgatg
    21541 gggatagtat tgacacttgc tggtatcccg atttatctct atttaaaacg tagatagcta
    21601 aaacattcga attttattag aactgcactt ctctgccaaa caaaatattt tatttaaatg
    21661 aggagtacgt ggaagaaatg tcaaaagtac tcgttaattt tgatcacgta aatgtcgttt
    21721 tgtctacgat gaaatagcaa agtaaaagac agaaatcggg ctcaaccgat ttctgtcttt
    21781 tactttgatt tgcgtaactg aactattcgg cgtacgccgc gataaatatt taataaaacc
    21841 aagcaaccag aaatgaaaat gggaagccaa atcagataga cagggtagcc aagcacttta
    21901 gacaaagcat gtggagtcat tttatccatt tcaagaagtg cttgctgcca agtctgaaga
    21961 ttgaagacta gcatgaaacc cgaaataatc aggagaataa atcctaaata atgaattgta
    22021 gttctttttc ttacataagc gatcgtagca taaaggaaca gtaaaaaaat aggtacgcca
    22081 aaaacaaagt acatattcag catctcgaca ccccctttgt gtttatctta ctttactttg
    22141 aaagaaatga gaaataatag cctcgttact tgcttgaaac agcaaaggac tgctaagata
    22201 agagagatac aaagaatcaa ggaggagtca tatggcaagt tatatcgaac cgattcgttt
    22261 tgcgctgatt gtttttccat ttttagcctt agcgatctca tctgtttttt ttatttatga
    22321 atatcgaaag tatggaacat ttctagtaac aagggcagtt attttgtatt ctttcgtttt
    22381 ttatttattg tgtgcgtatt ttttggtgat cttaccactt ccggcaaagg agacggttgc
    22441 ccaaatgaca gggccaaaga tggagctgca tttatttgct tcatggcaac atttcagaga
    22501 caacacggta ttggtcttgt ctgaacctag tacctacctg ccggcaatga agcagagtgt
    22561 atttttggaa ccagctttta atgttttatt actcatacca tttggcattt atttaagata
    22621 ttatttccgg ctttctttta tgaaaacgat gattgctagt ttctgccttt ctctattttt
    22681 tgaattgacg cagctaagtg gactttattt tatctaccca agaccatacc gcttatttga
    22741 tgtgaatgat ttagtgacaa atacattggg tggaatcatt ggttttgtcg ttacgccgtt
    22801 atttacattt atgcttccta caagaagacg aatggatgaa ctttcttatg aaaaaggaaa
    22861 gactgtctca ttgactcgac gcttggtcgc ttatttgatc gactggacat ttttatctct
    22921 tattaatttg gtagcggcga ttttctttaa aattgcgttc gattcagggg cagttacttc
    22981 tcatatctgg tggcttttat tagaagtagg ggtatacttt atgattgtac cgtttataac
    23041 caatggatgg acacttggca aaaaaattgt gcgtatccgt ttggtggaag aagaccgcga
    23101 acgaatttct ttaaaagcat tgatgatccg ctacgggtat ctgtactttc ttttttatgg
    23161 tttaagctgg ttggggcagt tgcttcagca aatcatgaat tcgacaacga atacggtgtt
    23221 gcagatgagt gcagtattca tttctctcgg tgtcttgtta ctacaaggta tttttatttt
    23281 aaatatcttg ctatcatttt tgagaaaaaa acggattctg ttttatgaaa aagctagtca
    23341 cacatatact gttagcacga ttggccaaac aaaggatgat gattctcgaa attagctgag
    23401 caaaaacgct ttgtctgtgt tataatgcca aagtcgtgat aatttaaaga gaagaggtgc
    23461 acgaatgaat aattttgata tattccgctt caaaccgttt atcaatgaag cgttaaccgc
    23521 aaagggcttc aaacagccca cagaggtcca ggaacgtttg attcctttaa ttgcaaaagg
    23581 aaaaaatatc attgggcaat ctcaaactgg tacaggaaaa acacatacgt ttttgttgcc
    23641 tttgtttgaa aaaatcaatg cagaaaaaga ggaagtacaa gttgttatta cagctccaag
    23701 tagggaacta gctgcacaga tctatgaagc agctacacaa atcgctaaat tttctacacc
    23761 ggagatccgt gtctcgaatt ttgtcggcgg tacagacaaa cagcgtcaat taaatcgtct
    23821 gcatcaccaa cagccacagg ttgtagtagg cacgcctggt agaatattag acatgatgaa
    23881 tgaacaagcg ctgaagattc acaccgcatt tgcatttgtt gtcgatgaag cggatatgac
    23941 attggatatg ggttttttaa atgaagtaga ccaaattgca agtcgattac cagaaaagct
    24001 gcagttttta gttttttctg ccactattcc agaaaaactt cgtccattct tacgaaaata
    24061 catggaaaat ccaatcattg aagaaatcaa accaaaagca gttatttctg aagacattga
    24121 aaattggctg atttcaacaa aaggtaaaga tgagaatcaa atgatttatc aactgctgac
    24181 aattggtcat ccttatttag caatcgtatt tgccaataca aaacagcatg tggatgaaat
    24241 tgccgattac ttgaaaaacc aaggcttgaa agtagcaaag attcatggag acatcacccc
    24301 aagagagaga aaacgagtga tgcgacaagt acagaatctg gagtatcaat atgttgtagc
    24361 gactgattta gctgctagag ggatcgatat cgaaggtgtc tctcatgtta ttaatgcaga
    24421 aattccagaa gatctagact tctttatcca tcgtgtcgga cgtactggac gtaatggctt
    24481 aaaaggaacg gccattacgt tatattcgcc aaatgatgag caagccattg atgcgataga
    24541 aaaattgggc gtctcatttg aaccaaaaga aatcaaaaac ggggaaatcg tcaaaacata
    24601 cgatcgtaat agacgtgcca aacgagaaaa atcaaaagat gtattagatc ccacgctgat
    24661 tggtcttgtg aagaagaaaa agaaaaagat caagcctggt tataagaaaa aaatcgattg
    24721 ggcaattgca gaaaaaaata aaaaagaacg caaaatcgaa cgcagacagc aaagccgtac
    24781 tgctcgtaaa aataagaaaa attcacataa ataaaa
//
LOCUS       DAFELK010000044        24811 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFELK010000044
VERSION     DAFELK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.045"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            129..1388
                     /locus_tag="LP433_002008"
     CDS             129..1388
                     /locus_tag="LP433_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBL2006148.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(1477..2424)
                     /locus_tag="LP433_002009"
     CDS             complement(1477..2424)
                     /locus_tag="LP433_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2006149.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            2818..4110
                     /locus_tag="LP433_002010"
     CDS             2818..4110
                     /locus_tag="LP433_002010"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBL2006150.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            4125..5894
                     /gene="aspS"
                     /locus_tag="LP433_002011"
     CDS             4125..5894
                     /gene="aspS"
                     /locus_tag="LP433_002011"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBL2006151.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            6003..6878
                     /locus_tag="LP433_002012"
     CDS             6003..6878
                     /locus_tag="LP433_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2006152.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            7144..9027
                     /locus_tag="LP433_002013"
     CDS             7144..9027
                     /locus_tag="LP433_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL2006153.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(9102..9386)
                     /locus_tag="LP433_002014"
     CDS             complement(9102..9386)
                     /locus_tag="LP433_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL2006154.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(9376..10110)
                     /locus_tag="LP433_002015"
     CDS             complement(9376..10110)
                     /locus_tag="LP433_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBL2006155.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            10239..10862
                     /locus_tag="LP433_002016"
     CDS             10239..10862
                     /locus_tag="LP433_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBL2006156.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            11054..12175
                     /locus_tag="LP433_002017"
     CDS             11054..12175
                     /locus_tag="LP433_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBL2006157.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            12182..15310
                     /locus_tag="LP433_002018"
     CDS             12182..15310
                     /locus_tag="LP433_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBL2006158.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            15329..18523
                     /locus_tag="LP433_002019"
     CDS             15329..18523
                     /locus_tag="LP433_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBL2006159.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(18669..19376)
                     /locus_tag="LP433_002020"
     CDS             complement(18669..19376)
                     /locus_tag="LP433_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL2006160.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            20141..20539
                     /gene="spxA"
                     /locus_tag="LP433_002021"
     CDS             20141..20539
                     /gene="spxA"
                     /locus_tag="LP433_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL2006161.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            20871..21524
                     /locus_tag="LP433_002022"
     CDS             20871..21524
                     /locus_tag="LP433_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBL2006162.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            21750..22748
                     /locus_tag="LP433_002023"
     CDS             21750..22748
                     /locus_tag="LP433_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBL2006163.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            22924..24732
                     /gene="pepF"
                     /locus_tag="LP433_002024"
     CDS             22924..24732
                     /gene="pepF"
                     /locus_tag="LP433_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBL2006164.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT         8344 a         4250 c         5205 g         7012 t
ORIGIN      
        1 ttaagttaga ctgataaact ctaacttaag tggctttttt gtctgcaaaa agcgcttctt
       61 ttgtcagcag tcggaaaaaa agttaagctt aaattataca agttattttt tataggaggt
      121 tgctgaagat gaaagaagta ccagtagtag atatcaaaat cacagattta aaaaaattgt
      181 atcaaaaagg atacaacatg ttggaggagt tacgccatga agcggacgct cccgtcgtca
      241 aagcaaagat tttcaataaa gaagctatca cgatctacgg atcatcagca gcaaaagtat
      301 tttatgatcc aaggaatttc aaacgaaaag gtgctatgcc aaaattagta ttgaagacac
      361 tttttggtca aggtggagta cagactttgg atggagctgc tcatcaccat cggaaaaata
      421 tttttatgga tctaatgaca ccggaaagaa tggaagatta tcatcgtatc ttagataaga
      481 atctgacaca agcacttgaa gcacagcatg gtcaatttga actatttgat ttaagtaaga
      541 tggttttctt tacatctatt tgcgagtggg caggtatcaa tttatcagcg atttctaaag
      601 atgaggtcga aaaattagca gaatatcaaa tctctatgat cagcggaacg tttacttctc
      661 cgattgatca cataaaaggt gtcgaaaatc gcaaaaaatc agaaaaatgg gcgcaaggct
      721 tgattgaaga agctcgacaa aatcctgtgg ctggaaaaga aaatgtggca ttatatgctt
      781 ttgccaatgc cacagattta gatggtcagc ttttacctct ggaagtggca gctgttgaat
      841 tattgaacat catccgtcca acggttgctc taactgtgtg ggcggcattg atgggacatg
      901 cacttttcag tagaccagat ttgtatcagc aattaaaaaa tgacttttcg acgttacaag
      961 atccgtttat tcaagaaatg agacgctatt atcctttctt cccaatgcta cctgcgattt
     1021 cgctgaaaga agtagaagta gatggttatc gtataccaga aggcagttgg gttattttag
     1081 atttatatgg aacagaccat gatgaacgaa cagttgaagc gccagattcc tttatgatca
     1141 aacggtatgt agggaaagca aaagatattt cctataaaga agaatatgag atgattgcac
     1201 aaggcggggg aaattttcga caaatgcatc gctgtgcagg agaatggatc actcttcata
     1261 gtctacgtgt gttttccgat cagctagtaa ataagtttga gttctctgta cctgaacaag
     1321 attggacgat tccattcaat cagtttccga cttatccgaa tagccgagcg ctactttaca
     1381 agaattagat tagcataaac ttatcgaaaa aaaggaagat caaacagtgc tgatcttcct
     1441 tttttcatat tactataaat tgataaggtc aattgatcaa aatccacgaa atgcttcatc
     1501 aatggtttga taatcttcat tggataaatg caaatctaaa gcttggacat tgtcagatac
     1561 ttgctctgga cgcttagctc caggtataac tacagacact cgtggattct tcatgtacca
     1621 agctaaaaca agttgcgcag gagtggcttg gtatctttta gcaatggggc gaagtacatc
     1681 gacagcggtt aaaatttctc tgaaacgttc tccttggaaa tctggatttc tttttcgagg
     1741 atctccttca ccaaattgtt tttcctcacc aagttcatat tttcctgtca gcaaaccgga
     1801 agcaagagga aaatagggaa caaaactgat tttgtttttt tcaagataag ggaataattc
     1861 tttttcagcc tgccgatgga tcaaactgta tttatcttct actacatcga catatccatc
     1921 tgcattcgct tctttcaatt gttctaacgt gaagtttgac acaccgactg ctcggatttt
     1981 tcctgcttct tttaattcgt gcaatgtagc aactgattca ttttttggtg tgctttcatc
     2041 cggaaagtgg atataaaaaa tgtcgatgta atcagtttgc agacgtttta gtgcatcttc
     2101 caccgattgt ttgagaaact caggagaatt atcaaatgtt cgccctttat ttggtacatg
     2161 agcagctttt gtagcgatga cgacacgtga gcgatcatat tctttttcct tcagtacctc
     2221 gccaatcagt tcttcggaac ggccgtttcc gtaagcataa gcggtatcga tcaaattgat
     2281 cccgctattc aaagctgtac gaactacttg ttttcctgtc tcatcttcca aaccgtcaaa
     2341 aagattatgt cctccaacgg catttgctcc taatccaagc tgttctgcgt agacttgtga
     2401 atgtccgatt cttatttctg ccatagctga ttcctccttt ttgtctagtc taaaacaaaa
     2461 taccaaaaag ctgaactaaa acgtttttgt gaggggaaat agtcagatat ctcttgactt
     2521 tgagactggt ttttagtagg ttataagtaa tatcgaatgt caatgaaaga gcgagtaagt
     2581 ttttgaaact ttacaagaga ggatcatcga ggctgaaaat gatctaaagt ttcattagcc
     2641 taaagacact ctggagatgg acgagtgaaa agccgtcccg cgtacgagcg ttattcgtaa
     2701 gaggaaagag aaatctttca aaattaggtg gtaccgtgta tgaatttcat tcacccttgt
     2761 tcatgatgaa caagggtgat ttttttattt acatagctaa gaaagggaga gaaaactatg
     2821 agtttccaaa gaccaaaagg aacaaatgat attttgccag gcgaatcaga aaaatggcag
     2881 tttgtcgaag aaacagcacg tttattattc agagattatc agtataatga aatgcgtaca
     2941 ccgatttttg aacactatga agtgatatcc cgaagtgtag gggatacaac ggatatcgtt
     3001 tcaaaagaga tgtatgattt ttatgacaaa ggggaacgcc atgtgacgct tcgaccagaa
     3061 ggtacagcac caatcgttcg ttcttttgtt gagcataaat tgttcggccc agagtatgcg
     3121 aaaccgttca aaacttttta tatgggacca atgtttcgct acgaacgccc tcaaaaagga
     3181 cggttacgtc aattccatca aatcggagta gaagcatttg gatcagaaaa ccctgcaact
     3241 gatgtggaga gcatggtgat ggcacttgat ttcttcaaac agttggggat cacgcaaatc
     3301 cggctagtca tcaattcatt aggtgataaa gaaacgcgtc aagcctatcg tcaagcattg
     3361 atcgactatc ttttaccttt tgaatcagag ctgagtgaag actctaaacg ccgccttcat
     3421 gaaaatccat tacgcgtatt ggacagtaaa gacaaacgag atcaaaaatt tgtggcagaa
     3481 gctccatcta tcttagatta tctaagcgag cctgctcaaa aacattttga taccgttgtt
     3541 tccatgctgg atgcattggc tgttccttat gaaatcgaca gtaatatggt tcgcggacta
     3601 gattattaca cacatacgat ttttgaaatc atgagtgacg caccaaaaat gggggcacaa
     3661 gcaacgattt gcgcaggcgg acgttatgac aatctagtgg aagaactagg tggtccttca
     3721 acacctggct tcggatttgc aatgggtatc gagcgattac tcttgactat ggaggcagag
     3781 gaagtagtta tccctgcatt taatgagttg gatgcttacg tggtcgcact cggagacgaa
     3841 acaaatatcg aagcattgaa agtggtccaa gcgattcgaa actttggttt ttcagctgac
     3901 cgcgacttca tgaaccgtaa agcaaaagcg caatttaaga cagcagataa agcgaatgcc
     3961 aaattagtat tggtgatcgg tgaagatgag cttgctagtc aaacgattaa tgtcaaagca
     4021 atggcaagcc gaaaagaaaa aagttttcca ttagaagaga tatatgaaca ttttgatgaa
     4081 gtctatgatg aaatgacttt attcgagtag gaggaaaaaa ataaatggca caaagaacga
     4141 tctattgcgg attagtttcc gaacaacaat tagaacaaac agttacatta aaaggatggg
     4201 tacaaaaaag acgagacctt gggggagtaa tctttatcga cctacgtgat cgtgaaggaa
     4261 tcgttcaaat cgtctttaat cctgaaatca acaaagaagc atgggaaatc gcggataaat
     4321 gtcgcagtga atacgtgatc gaagtgactg gggaagttag aagacgcgga gaaaatgcag
     4381 taaatcctaa aatggccact ggtgaattcg aagtgattgc aagtgaaatc gtgattttga
     4441 atcaagcaaa aaccccgcca tttcaaattg aagatgatca agcaatcagt gacgaaatac
     4501 gtttgaaata tcgttatttg gatctgcgtc gtccaaaaat gactaaaaac atcaaattaa
     4561 gaaatgcgac aacaaaagcg attcgtcatt atttagatga taatgacttt ctcgatatcg
     4621 aaacacctta cctagggaaa tctacaccag aaggcgcaag agactaccta gttccttcac
     4681 gtgtccatgc tggacatttc tatgcgttgc cgcaatctcc tcaattgttt aaacaattgc
     4741 tgatgaatgc tggattcgac cgttattatc aaatcgttcg ttgtttccgc gatgaagatt
     4801 tacgtggaga ccgtcagcct gaatttacgc aagtagatat tgaaacaacg ttcttaacag
     4861 cagaagaaat ccaaacttac acagagggat tgattgcgaa ggtaatgaaa gaagttcgcg
     4921 gtatcgaagt cacattgcca tttcctcgta tgacctatga tgaagcaatg gctcgctacg
     4981 gcagcgacaa accggataca cgttttgata tggaattgat cgatctaagc gatacagtca
     5041 aagaagtaga attcaaagtc ttccaaatgg ctcttgaaaa cggcggtgtc gtgaaagcat
     5101 tgaatgctaa aggcgctgca gatcgctact cacgaaaaga catggatcag ttaggtcaat
     5161 atgtaggaca attcggagct aaggggcttg catggctgaa agtagaagaa gacggattga
     5221 aaggtccaat tgctaaattc atgggagaag caacagaagc aatcattaaa gcaacagatg
     5281 caaaaccagg tgacttgctg atgtttggcg cagataaaag tgaaatcgtc gctgctgcat
     5341 taggtgctat ccggacacgt ttaggaaaag aattaggact aattgatgaa tcgaaattca
     5401 atttcttatg ggtaactgat tggccacaat ttgaattttc agaagaagaa ggtcgatatg
     5461 tctctgctca ccatccattc acgatgccaa aagaagaaga tatcccgtta ttggctgaag
     5521 accctgcaaa agtctatgca gaagcttatg atatcgtctt gaacggttat gaactaggcg
     5581 gaggttctat ccgtattcat actcgtgagc ttcaagaaaa agtactagaa actctaggct
     5641 ttacaaaaga acaaatggaa gaacaatttg gtttcttgtt aacagcttta gattacggat
     5701 tccctccaca tggcggtatt gcattaggat tggaccgttt tgcaatgtta ttagccggag
     5761 aagataatat tcgtgaagtc attgcctttc ctaaaaacgg aaaagcagca gatgtgatga
     5821 gtgatgcacc aagtatggtt tcgcctttac aattgttcga attgaatatt gatgtaacga
     5881 atatagaaga atagccgata aaaaggtaaa aaggatttgt cgaatacgct tcttttgaca
     5941 accttgattt aattgaaaaa cactttataa tgaagccata acatataaag cggggctttt
     6001 ccatgaaaaa aacattcgaa aattgggctt atcatgatta cacgaccaag ctttcggtat
     6061 ctatcgttta tgcgttgatc gcatcagtcg cattgaattt cttttatcag ccaggacata
     6121 tttattcaag tggtattact ggtctagctc agattttgac gactttgtca aaatcactga
     6181 taggattcga agtaccggta tcaacaactt tgtatttact gaatatacct ttgtttgtat
     6241 tggcgtggtt aaaaatcggg aagaagttta caattttcac ttttatcaca gtcactttga
     6301 cctccctttg tatccatatt ttaccggaaa cagtcctatc taccgatcca atcatctgtg
     6361 cgttgtttgg gggggctgtg atgggactag gtattgggct agcgttgaga aacggcctat
     6421 catcgggcgg tctagatatc gtgagtatca cgattcgtaa aaaaacagga aagtcgattg
     6481 gttctatttc gatctacttc aatgcattga tcgtttttgt tgccggaatt ctatttggct
     6541 ggcaatatat gttttacagt acgttgtcta ttttcgtcag tggaaaagta actgatgtcg
     6601 tttatactaa acaaaagaag atgcaggtaa tgatcgtaac gaaacatcca gaaaaagtag
     6661 taaatgaaat ccaaaactgt atgcgtagag ggatcacgat catcaatgaa gcagaaggtg
     6721 cttataagca tgataagcag acagtattga tgacgatcgt tacacgatac gaactgcctc
     6781 tacttagaga agcaatgaaa gcttctgatc cacaagcttt tgtaagtatt gcagaaaacg
     6841 tccagatact tggtcgtttc tatgaggatg gcatttagat cgagtttgac aaaaattcat
     6901 gaaatactgc tgtagacaga cgttcgtttg tctgcagttt ttttctacca tagtagaatc
     6961 agcaaagaaa aactgctttt ttatttgaaa ttttcttaaa gttgaaaaaa agcatgttta
     7021 tttttttaaa tttatgggat gatagaaaaa aatagtagag aaaggacacg attctacttg
     7081 ctattttcac ttaatacccg tatattacga atgaaaaaag tttatgaaaa gttggaatat
     7141 tgaatggaaa aacaaaaaag gttaaaaaac agccgctaca tcactgggtt tgatgggctc
     7201 cgttcattag ctgtggtggg tgttatcttc tatcaccttc tgccaactag tatgaaaggc
     7261 ggctatttgg gcgttccgat ttttttcgtc gtatctggtt atttgatcac ggatctgctg
     7321 cggcaggaat gggaacaaaa tggaaaaatc aatatttggc aattttatgt cagaagaatg
     7381 aagagactct atccggcact tgtttttatg cttgtgacag cttcggctta tatcactttg
     7441 tttcagcgag ggctgttaaa caatcttcga ggagttgtgg tcagcagctt actgtatgtc
     7501 aacaactggt ggcaaatcaa taacggttta tcttatttcg atcgatttgc taatgagtca
     7561 ccgtttacgc atatctggtc tttagcagta gaaggtcaaa actatttggt ttggccgatc
     7621 ttgtttgtat tgttgatggt atttgttcgt aaaagaaaat ggatctttta tactgtgtta
     7681 ggtacatcct tcctctccgc catcttgatg atgatcttgt atacaccagg aggcgatcca
     7741 acccgtgttt attacggtac cgacactcgt ctgttttcta tatggttggg aagtgcgctt
     7801 gcgtttgttt ggccaagtac gcgtttaaag aaaaacatcc cgaaacaagc gaaaaatatt
     7861 ctgaatatcg ctggaggaat ctcgcttttg gcactgattc tttgcttctt ctttttagat
     7921 gatcattaca atttcatcta ttacggagga atgctcctag tgagtctgtt atgcgtagtg
     7981 ctagttgcag tgacagcaca ccccggagca agtttgaatc gatggctgac aaatccagta
     8041 tttacttgga ttggcaaacg aagctatggc atttatctgt atcagtttcc agttatgatt
     8101 ttttatgaag caaaggtgac tgatattgcc gatcatgttt tgttgcatac tttagtggaa
     8161 atcacattga ttctaatcat cagtgaactt tcttatcgat atgtggagcg tccgctagca
     8221 cgttttgatt atggtcgtac attccaagtg atgaaaggat ggttcagcaa accgatcatc
     8281 agtaagagca aaccatgggt tgttccaggc acattacttg tagcaattgc actcgttggt
     8341 ttcgttacgg caccgaaaaa cgctgtaaca gccgatcaaa aacaactgca ggcaaaaatc
     8401 gctgaaagta aaaaattagc agaagaaacc agaaacaatt cagaaaacac cactagttcg
     8461 gttgaccaag cgatccttga taagtacgag ttgtccaagg cacaagggaa taaggcacaa
     8521 aaattagaac taacggcatt tggtgattca gttatgttgg atgctgcaac ggatctacaa
     8581 gaactttatc caaaagtagt ggtagatgga gatgtcggac gacaattata tgccagtgta
     8641 ccgtacattg aaaaattaaa ggaacaagat ttgttgaaag acactgttct gatcggacta
     8701 ggaacgaatg gctcattctc ggaagctcag tttgatagtg tgatggatgc aatcggtgat
     8761 cgaaaagtat actgggtcaa tgtccgagta ccgacgaagc gctggcaaaa tgacgtgaat
     8821 gcgatgcttg aacagatgac gaaaaaatac gacaatatga cgctgattga ttggtacagc
     8881 tacagtaatg accatagtga ctggttttat gatgatcaag tccatccaaa tcctgaaggg
     8941 atgacacatt acattcactt agtcagcgaa gccttgctag gaggaagttc aagtacgaac
     9001 agcagtgaga caaacgtgac agaatgatag ctacaaaaaa cttcaggcaa aaacatttgt
     9061 ttttgcctga agttttttta tatttaccgt gtttttaaca ttcatataga ttcaggaagc
     9121 aaaacggttg agtgtgtctg taaataacgt tctttttgtt ttcgggtgag ttttttgaat
     9181 gcagcttctg cttttgttgc ttcgcttctt gaagaaaata cttctgcatg gatcatctta
     9241 acaggtcttc ttttttgaag acgagtatat ttagcaccag taccattgtt atgttcctct
     9301 aatcgtctag aaagatcggt tgtatatcca ccataaaatg tctgatcttt acagaataat
     9361 acgtaaaaat aatgttcatt tgccatagag catctcacga atctctgcag tgtattctcc
     9421 atccatattg taagtgatca atggtggagc gactttgaat ccgtctaatt tgccttcttt
     9481 gattccttca actaacaaaa tatttgcctc ttttccaggt tttgggtaaa caaattggat
     9541 ccttttaggt gcaattcgat agtcttccat gacctgaatg atttctaaga accgatcagg
     9601 acgatggacc atagtaaagc gtccatttgt ttttagtagc ttacttgaaa tatcgatcac
     9661 ttcttctaac gtcgtatgaa tctcatgacg ggcgattgcc aggtgtttat tagggttcgt
     9721 tttatttgtt ggcagccctt tgaaataagg tggattacag acgactaagt cacaagaatt
     9781 atgtcgaacg acagataagc tgtctttcag atcgatggtg tggacagtca tttgttcatt
     9841 taaatggtta agcgcgatac tacgtcttgc catgtctgct agacgaggtt gaagttcgat
     9901 agcgtcgata gccgcctggg ttcgtttact taaaaaaagt ccaactgcgc catttcctgc
     9961 acaaaggtca acaatcttcc cttttttagg tacacgggaa aagtgagcaa gcagcacagc
    10021 atctaaagaa aaagaaaaca ctttggaact ttggataatc ttgatatctt ctgcgtataa
    10081 ttggtcgatt cgttcgtctt cgtgaagcat ggattccctc caaaatgaaa aaaatagtcg
    10141 tctgtattat actattttta ttaaaaagaa ccaaggtggc ttgtcaaacc tctatttttt
    10201 atgcatacta tgaccataag aagggaaagg aagagactat gttttatcga tttatgcgcg
    10261 gggtagttcg agtactatta gccttagtta atggaaatgc ccgctatgag aataaagaag
    10321 ttttaccgca agatgagaat tacatactag ttgctcccca tcgtacttgg tgggacccat
    10381 tatatctggc ggtagctgca gcacccaagg aattcagctt tatggcaaaa gaagaactgt
    10441 tcaaaaatcc agttctgcga tttatattaa ctcgatccaa tgcttttcca gttaaaagag
    10501 aaaatccagg accaagcgtc attaaaacac ctgtaaagat tttgaaatcg acaaatttga
    10561 gtttgatcat gtttcccagt gggacaagac atgctacaga acttaaaggc ggaatggcat
    10621 tgatttccag aatgtctaaa gcgaaaatcg tgccagctgt atatcaaggt ccgttgacac
    10681 ttggggatct gttcaagcgt cagagagtga cagtgcgttt cggcgaacca atcgacttat
    10741 cagatatcaa gaaaacggat aaagaaggta tggcggagat cgaacgacga acacaagcag
    10801 cttttgacaa attggacaaa gaagtgaacc ctgatttcaa atatgaagtc aaaaaaaaat
    10861 aaaatgataa gtttatgcgt gggcggtctt ttgaatctac tgtcctgttc agttcagact
    10921 ttttcaatga aaacgaggga gagacgtcaa gtctgccctc tttttgcgtt ccaatatgta
    10981 aaatagaaga caggtgtcat gtaatggatc aaagtgttat aataattaga aggacatttt
    11041 ttgaggtgat tgaatgcgtt ttttacatac agccgattgg catatcggaa aaaaactaca
    11101 aggttatgac ttgattgaag accagcgtca tgtactatct tctatactag atatcgcgaa
    11161 agaagaaaaa gtagaggcaa tcgtgattgc cggagactta tatgatagga gtgtcccagc
    11221 tgttgatgcc gtagaattat acaatgaatt gatggtcgat tggaatttaa aggaaaagat
    11281 cccgattttt gctatatcag gaaatcacga tagcagtacg agactttcag cgggtacgcc
    11341 atggttcagt tattcgaact attttttgcg aacacagcta gcagaagcat ttgaaccagt
    11401 cgagtttaaa aacgtacaat ttttctttct tccttacttt gaaccaattg cagcgagatt
    11461 atattttgaa gatgacaata tccgaacgat caagcaagcg gtagccaagg tgatagataa
    11521 aatgcaggag ctatttgatt cagaaaaaaa acaagtattg attagccatt tttttgtaat
    11581 gggaagtgta aaatctgatt cggaaacgaa aatcgaagta ggcgggttgg attcgatccc
    11641 tggtgaacta cttacaccgt ttgattatgt agcactagga catttgcata atcaagctgc
    11701 tttgagacag gataatgctc gctatagcgg ttccccattg aaattctctt tatctgagat
    11761 caaccaaaaa aaaggcgtat ggatcgttga cctgacaaca ggcctggagt tgaattttag
    11821 ggagatcgaa cccctgcatg atattgaaga aataacagcg agtttcaaag aattgctgga
    11881 tcctgccttt tatcagtccg tcaatcggga gaattacatc tatatctatc tcactgatag
    11941 aacgatcatc ccgaatatga tgaaccagct tcggcaaata tatcctcgta ttttggggat
    12001 tgaacgggca aacggtcgag cagaacaaac aaagcgcaaa cgaaaagtac tagaaatgaa
    12061 agatcctcaa aaattagcag aagcattttt tagtgaaatg acggaagagc agctaactgc
    12121 aaaccaagaa aaatggctcg gagaaacgtt gcaagaaatc atggaaatgg aatgatcaag
    12181 aatgaaaccg aaaaaattac aacttaaaaa ttttggtcct tttatcaatg agaccgtaga
    12241 tttttcacgt ttgacagaag caccgctttt tttgatcagc gggaagacag gagctggcaa
    12301 aacgacgatt tttgatggga tcaccttcgc actttttggt gaaacttccg gaagacttcg
    12361 ctctggaaaa gagatgcgtt ctttgtttgc tacaccagac gaagaaacaa gcgtgacttt
    12421 ttcttttgaa catcagcaga tgagctatga aatcgaacga aaaccagaac aagttttagc
    12481 aaaacgaaaa ggaaacggaa caaaaaaaca ggcagccaaa gtaacgttga ccatttttga
    12541 tgggaaagga aaagaaataa aacaaatcac aaaacgtaca gaagcagatc agttgatcag
    12601 agaactgatg aatctcgatg cgaaacagtt ttctcaaatc gttttactac cccaaggaga
    12661 attccgtaat tttttggttt catcaagcag tgataaagag actgttttac gtcatttatt
    12721 cggtactcaa tttttccaac agttcaatga gcgattaaaa gaaaaagcaa aacaacagca
    12781 acaaaaattg gatcatttag agcaagagct gcatcttctg caaaaaaggt ttgttttagt
    12841 caaagaagag gaaccagcag cagggtttga agccgtttta gcccaatgga caaaccatca
    12901 ggcaatactc gaaaaacaaa tcacggaaga aaaagaagct ctaacggaac ttcaggaaaa
    12961 acaaaagcaa ctagaaaatt cctactatcg ttttgaaagc ttgaaaaaaa gttatgaaga
    13021 aaaaacgata ttaataaaca agcaaaagga attagctgct caaaaagacg aaatagagga
    13081 aaagaaacga tggattgggt attatgaatt tacgcaacga ttagtcgaac caatccagcg
    13141 cctacaagaa ataaaagttg aaaaaataga actgtcacaa aaaagtagtg agcaaacaaa
    13201 gaaactagcg atgactacgc agaattatga agagtggcaa aaaaatgaag caaaccgcgt
    13261 acgccgacaa acaaaaatca aagaagctgc tcaaaaactg caaaacaaac agatgatggt
    13321 gccaattgtc gaatccttac gtagtaaaaa acaagacgca gaacaattaa caatttcatt
    13381 ggataaagaa gaattgaatg ccgagaagct gtatcaaaat ctcgctatct atcaggaaag
    13441 aactcgaatt cttcaagaaa atttactgga tcaggaaaaa ctgcaagaag atcgtcttgc
    13501 ttttggacag ttaaaatatc tagatgaaaa gcagcaagaa atagaaaaac aaaaagcaaa
    13561 agacactggg tcgctcgcac agataagaga agaactcaaa aaagcaactg aagaaataac
    13621 aaaaaatagt cagctattga aagaacagac agaacaagca gaacagctga aaagccaatg
    13681 ggcaaagcag caaattgctc gtcttcagct ttttttgcgt ccaggggagc catgtcttgt
    13741 ttgtggatca acggaacacc ccatacaaca attaaaacac gaacagccaa ataaggaaga
    13801 tatcttaaaa gtagaacaac aactggcaga agctgagtct gctgtagaaa gaactcagca
    13861 aatcattgcc aaaagtgaag cacatgaaaa taatcttcaa caacaattat cagatttaga
    13921 acaaaaaatc atggcaacga atatacaatt ggctgaacaa gaagaacact tgcaacaggc
    13981 tttgaaaaag gcatttcctg agataacaga acaaaaaaca aaaacaactc ttgtagtaat
    14041 cgaacaatct ttagatagac gaaaaagcaa gatggccaat gcaagaatag agctggaaga
    14101 aataagacaa caagcagaaa agctcgaaca acaattagct gtctacaaac agcagcagac
    14161 agaaaaaaat aatcagctcc agcaactgca aggagaaatc aaaagtttag aacaacaatt
    14221 gcaagatacg gatagtaact gtttagaaga ggagatacga cgacttgaaa aacagttaga
    14281 agaagactcg aatcaactag ctgttgagca gaaagcagga gtgcaattgt tgcaagatct
    14341 tcatacgctt cggacacagc ttgatcttca acatgaacaa atagaaaaaa tagatgaaaa
    14401 aatagaaaag gaacaagaaa gaatagctaa aaagttagaa agccagtcgt atttttcaac
    14461 aattgaagaa atctgtgcat ttgcacaaca gcaagcacaa tataaagaaa accaacgtac
    14521 agttacttct tatcatgaag agcaattagt gacagctgac cggctgcgtc aattagaaaa
    14581 tatccagcta actgagacat tcccagatac agaagagatc agccaacagt tagaagaaat
    14641 aagacgtatg atcgaaataa agcaagaaaa gatatacggt ttacaagaac aaaaaattag
    14701 taatcaaaaa atctacgatg aatgtctttc gatttatcac acaagccaga cgaaattaga
    14761 tgagcttacg caattacagc agctttcgca aacattcaac ggagaaaatc ctaagaagac
    14821 tagtttggaa cggtatgtgc ttcaggttta tcttcaagaa gtgttacaag tagcaaatga
    14881 tcatctccaa cgtttaacga aaaatcgtta tcaatttgag ctagcggata ccattggcag
    14941 ttatcgaggg aaaaccggat tagaaatcaa tatctatgat gatcaggcag gtatgtctcg
    15001 aagtgcgcat accctgtctg gcggtgagag ttttattgca gcactttctt tagcattagc
    15061 tcttgccgat gtgatccaga cacaagctgg tggtgtagca atcgatgcat tgtttattga
    15121 tgaaggattt gggtcattag atgaagaagc tttggaaatg gcaatggaag ctttagaaac
    15181 gatcgaaagt gaaggaagaa tgatcggcat cattagtcat gtaagagaat tgaaagaacg
    15241 agtattacaa caaataagaa ttgatacaga aggtagcgga caaagcaaaa tacgctatca
    15301 acttggataa aaagggagat tggtaactat gaaatggagt attccagaaa aagtcattgc
    15361 acgtggacgt caatacttgc aagaaggccg agtgttatcg gttgtccctg accaagaaga
    15421 aaacgtgtgg catgcagaag tcttgggcag tgaattgtat atggttgatt tggatggtac
    15481 agcaaaagag atagattact gccaatgtcc ctattgggag gaacataaat attgtaagca
    15541 tacagttgct gtggaacttt atttacggtc gaaaaatcta tctcgtatca tgaaaaaaga
    15601 ccagccaatg ctagaaccgg taaaagcaac aagtgaggga gaaatcattg caaaaggttt
    15661 ttctcgtcta aaaacacaaa acaatcctca agcggtgcaa cctttgatta ttgaatacca
    15721 agtagaaacg attgagacta atcagtatca cccagagctt tctattttgg cactttactt
    15781 gcgtatcggt tcattggcat caccgaaaaa aacatatatc gtaaaaaaca tctatgattt
    15841 tttacaagct tacacagaaa aagaaactta cactgttaat aaacagtacc agtttcgtct
    15901 agataaacgg gcgtttcaaa aagaagatca aaaaatactc acgcatcttg caggaagtgc
    15961 tcagacgcat caattattag gtacgaacgg cttacaagtc aaaggaaaac tagataaaag
    16021 atatctgctt ctcccagtag aacaagcccg cttcctgtta gagcagatga atcagactac
    16081 acgtttgcat ctgcagataa atgaacaaaa cgatcaagga atacaatttt ccgatcaaaa
    16141 caaaccttta tcattcaaag tggaaaaatt tggagaagat tatttgctgc aagcattgaa
    16201 tgattttgat tttttcttta tgcattatca gtggggagtt atccaaggga cattttattc
    16261 tctgacgaaa tatcaacaaa cggtttatca aacttggaaa caattgattc gccgattgga
    16321 gaaaccagaa gtagtgttca agaaaaaaga attaccgtct ttgtttaaag agattatccc
    16381 tctgctgtca gagatcggcg acgtagctat tgcccctgca gtagaagagg aagtagcaga
    16441 tatccccgtc gaatttattt tctttttccg aaaagcaaaa ggaaaaatcc aagctcgagt
    16501 cgatttcgtc tatggcgaag tcatctattc gactgacccg aagcatgagg tctcgacaga
    16561 acaggctttt caggtgttac gtgacacagt agaagagaaa cgagtacttg atctattcag
    16621 aatgtatcgc taccagaaaa atgaaactgg ttatgaacgt ccattgccaa gcggggaaga
    16681 actatatgcc tttttccgca cagaactatc tgtcttccgt cagtttggtg aagtcagact
    16741 tggaagaaaa ttgcgagagt tgtatttaga tgcgcataaa catcaaccga aaatcgaagt
    16801 aaccgagacc ggttcatggc tcgatattcg attcgatgtg acagggatag aggagcaaga
    16861 aatcgatcat gtcctgcaaa gcttgctgag aaatgatgct ttttatacat tagaaaatgg
    16921 tcaggttctt tcttttgatt cagaagaatt tcaacaaaca agccaagtgt tgcaacaatt
    16981 acgggaatcg atacgtacag aagaaggaac gatccatgta cctaaaaatc aaggattgat
    17041 cattcaaaat caattggaaa aaagcaatgc tacttttagt gaatcgttcc aaacgatggt
    17101 acaagatctc attcatccag aaagatacca ggcacagctt cccaaaggat tgaatgcaac
    17161 gatgagagat tatcaaaagc aaggttttcg atggttgaag atgttaggtc attatcagtt
    17221 tggcggtatt ttagccgatg aaatgggact tgggaaaaca ctacagacaa ttgccttttt
    17281 actttcggaa aaagaagaac ggaaaagctt ctctgctttg atcgtagcgc ctgcgagctt
    17341 aatttacaac tggcaggcag aggtgagaaa attcgcccct tctttaagta tccaagtaat
    17401 caatgggaat aaaaaagaac gtgaagaatt actggctaaa gacacagata tccgagtgac
    17461 ttcttatgcc agcttaagac aggatctagc taattatcag tcgcaaaaaa ttgattattt
    17521 gattcttgat gaggcacaaa tggtcaaaaa tagcagtacg aaaactgcac aagcattgag
    17581 agaattagct gtacctcagc ggtttgcact gagtgggaca ccaatcgaga ataatttaga
    17641 agaattgtgg tcattgtttg caacgattat gccaggattt ttcccgacta aaacaaaatt
    17701 cagggaactt gccgcagaag aaattgcgca aatgattcga ccgtttattt tacggcgaga
    17761 taaacaaact gtgttgaaag acttgccgga aaaaacagag atgaatctat attctgcact
    17821 tacagaagaa caaaaaactg tttatttagc ttacttgcgt caaatgcgtg aagaaatcac
    17881 atcaatggat tctgaagcat tcaagaaaaa ccggatcggg atacttgctg gtctgacaag
    17941 actgcgacaa atttgctgcg atcctcgtct gtttattgaa gattaccaag gcggttccgg
    18001 caagctcgaa caagtaaaag atctactggt agctgccaaa gagaacaaac gaagagtttt
    18061 gctgttttct caatttacag ggatgctgac tatcttgcaa gaagagttag ccgagctagg
    18121 gatctcgaca ttttatttaa gaggcagtac gaaaccacaa gatcggttaa gtatggtaga
    18181 cgcatttaat gctggcgaaa aagatgtttt tctgatttcc ttaaaggctg ggggaactgg
    18241 attgaatctc acgggagcag atacggtcat cttgtatgac ctttggtgga atcctgccat
    18301 tgaagaacaa gctgctggac gtgcacatcg gatcggacaa aaaaatgtgg tagaagtgtg
    18361 gcgtatgatc tctgaaggaa cgattgagga acgcatggat tcactccagc aagaaaaacg
    18421 cgaactgttc caaaaagtga tccaaggtaa tgaagaacag ttgacgaaac tgactgaaga
    18481 agacatccgc atgattttaa gtgtaggaga aatcgaggag taagagactc gaaaaagcgt
    18541 tcagtaatgg gtaagaaagc ctttctaaag aagcgattgt ttatttgatt taaaaaatag
    18601 caaggaggct gggattccat tttatcccag cttccttgct atcatttttt tatttctatt
    18661 tttaaaggtt atacaaagat tgtcttcatt gtctctaaca gctgatcaaa agaagaaatc
    18721 tcgatatcgc aaattggagt ctgttcaatt ttgcgttctc gatggttgaa ccaaagcgct
    18781 tgccagttag cactttttgc acctagaaca tcattgtcgt aattatcgcc aacgtataag
    18841 gtctcttctg gaagcatatg aaattctttc tcagctagct gaaaaatctc tttttctggt
    18901 ttttggaaac ctgttgcttg agaaatgagc atattgcggg aaggaatcca attgttcaat
    18961 tgaagttgct tcagtttttt tgtctgatgg tcagtcggcc catttgtgat aattcctaat
    19021 gggacattct tttccttcaa gaaatcgagg gtttttttga cctcctcatg caagcagata
    19081 ttatcaagtt cttcctcgta aattttttga aataagaggc catcttcttc cgtaatatga
    19141 gggtagtcta aatcttttag tgattggctg atccgatgtg ctcgcatata ttctagtgtc
    19201 caatctcctg ccattacttt tgggaagttt tcatcactat gatggcggaa ccggatatat
    19261 agtggatgca tatctgcatc tgaaacaagc ggaacgactc ttttgaccgc gtttcgaaat
    19321 ggctgctgct gatcatacat cgtatcatca acatcaaaca caactgattt aatcaaaatt
    19381 ttacacgcct ttcggttttc attgattttt tcacaaatcc ttgactattg taacagaaaa
    19441 aattgtctaa aaaagctgat aaataaaggt ttttcttact atatttctat ttccttgaca
    19501 gaataaggtt tttatatttc agtttttttc actaaaaatc gtgaaacacg tcaataagtt
    19561 tgatgaacaa attaatcatt atggtagaag tcgattgatt tattttaatg caatctctgt
    19621 ggaattttcg aaagatttat ttttttaata cagtctcaat ataactattc aaacataaaa
    19681 taacgttatt tgatttattt gtttatagta aattttattt agtaatcatt gctttaaaat
    19741 actacgctta tataacagag aaaataagcg ttataataaa gaacagtatt atttaaaatg
    19801 acagaaaaca ttactattaa agaaataaaa aacataaaaa atcttaagaa atcggtttca
    19861 tttagctttt gagataaaat aatagtacag ttttatacgc tgtttcatat gtttagaaaa
    19921 tttgaattag atttgaaaac tctaattttt aaatgataaa aaaagcgaga atgctggttt
    19981 tactgtatat taaccttaga taactttcat ttttttaaaa aaattatgaa aaaaaggtag
    20041 ctatttaaaa gttgattatg tataatagaa acagatggga gattattatg atcttctgtt
    20101 acaaaaaagt gattcttatc acgaaaagga gtggtgcacg ttgttaacat tatatacttc
    20161 cccaagttgt acttcctgca gaaaggctcg tgcgtggttg caagaacatc agattccatt
    20221 tgttgaacgt aatatttttt cagaaccatt gaacagttct gaattaaaag cgattttaca
    20281 aatgacagaa gacggaacag aagaaatcat ctcgacacgt tccaaagtat tccaaaaact
    20341 gaacatggat ttagatgatc tgccgttaca agaattattg gaacttgtgc aaaacaatcc
    20401 tggattgctt cgccgtccaa tcatgattga tgataaacgt ctgcaagttg gttttaatga
    20461 agatgaaatt cgtcggttcc taccgcgcga tgtacgacaa ttagaattac gtcaagcaca
    20521 attgatggct ggattataga aggataatac gaaacttgga aaagactatt acaaagatag
    20581 tttttccaag tttttttgtt tttacaaaaa gtattcttga ttagatgtat aaaaaggtag
    20641 tagaagatga tgattgcacg aaaaatagag agggaaaatt agctgaaaag tcggctatat
    20701 agtattcgtc tgccaaaaat gttatagtta aataagatag cttgaaaggt tgaaaaatcc
    20761 gctggtttta ttaaattcgc ttaacagcga gatttttttt ctttacattt aagctgattt
    20821 cgctacaatg aatctatatt aaacattgtg gcaaagtgag gtgtagcaaa atggaaatgg
    20881 aacatattaa tgaaaatacg atccgtgtac taattggtca tgaagattta gaggaacggg
    20941 gcgtttcatt tttggattta cttggcaatc acaaagaaat cgaaaatttc ttttatagta
    21001 ttttggaaga agttgatatc gaagaggagt tccgaggaag cgaagctgtc actttccaag
    21061 ttttgccaaa aggagacgga ttagaactgt ttatcagtaa aaatcttccg gatgaagaaa
    21121 tttctcaatc agaagattct actgttgatt cagaagatgt gagtgacttt cttcgtcagc
    21181 agattattgg cagcgatccg gaggaagaat tatctggaag cgccctagaa gaacaggaaa
    21241 gacaagcaac ttttgctttt gaagattttg aacaagtgat ccaacttgca acagatgtcg
    21301 aactagagtc tgcttggact gatttgtatt tattcgaaga gcgctattac ctagtcgttc
    21361 acttctggat ggaaaatctc aaccaagcgg atgtagagaa tcagattgct cgaattttgg
    21421 agtttgctga aaagagcgat cgtacaccag aaacattgaa tgaatatgga caatgtctga
    21481 tggcgcgtaa tgctatcgag cgaacgaaat tttattttgt ataaatcagc attatagtaa
    21541 gagactgtga caaaaattgt gtcgcagtct ttttttcgta taaatgtgtt caaaagcttg
    21601 catctgcggt aacaagccca accaaacgaa aaatattggg aactattttt gtttagctgt
    21661 tcttattact tgatgcagaa tagctttttc acgccctctt ttttcgtgta aataaattct
    21721 tagacgtaaa taagttcaga gggagaaaaa tgctgcttgc aatgaatgaa tataataagt
    21781 gctgttttgc taaacatgca gaaaaaggaa agaaatatta ttgtcgtggc tgtcgaaaaa
    21841 gagtgatttt gaaaaaggga aagaaaaaat gtgctcattt tgcccatcaa aaatcagata
    21901 actgttcggt ctttagtgaa agagaatcaa aagagcactt acagttaaag gaatgcttca
    21961 tggattggct gggacagtca gtagaaccag tatttttgga agcctatttg ccgaggttgc
    22021 ggcaaaggcc ggatattttg ttggcgaatc tagcaataga aatccaatgt tctagactgt
    22081 ctcaccagag atttattgaa agaacccaaa attatttgaa taacagttac caagtatggt
    22141 ggatacttgg taattctttt cttggacaat cgcaattctc attgatagaa aaaagttgct
    22201 gctactataa tagaaaaaga ggagtgcatt gctggaaagc tgatctcaag aaacaaaagc
    22261 tttatttgta tcatcatatt acagagactg tatcagggca tatttccttt tgcagtagct
    22321 gctggacttt ttctagtagg gaccttaaag aaatattcac tagtaacgaa attaaaatga
    22381 accaaatgaa aaaaatagaa aaagtgagtg aagatgggaa gaaatggctg acacgccaac
    22441 ttattcacaa gcaaaagaat acagtatcca tacaagaaca atgctacttg cgtcataaac
    22501 atcttttgca tctatcatcg tggatctatc aaaaaagtcg gtttttcttt tatttacaag
    22561 aacaggtttt tctttatcga atgttgtacg aagaagcctt ggaaaaccag aaagttcctg
    22621 atttcaactc atggctttgc caaataaaag aacataaaag ggaatggctt tttcctatga
    22681 ttgatgaaga gatggtctat cagcagtttt ttaacgaatg catacacttg tcttctttga
    22741 aaaaatagta agtataaaaa taggctagga atcggttttc tatgtaaaac aagatttagt
    22801 tatgctaaaa ttgatggaag cagacacatg aatgagtaga aaagttagat gctgtgacat
    22861 gtggatgtta gactatgatc tattttgata gatagagcta agggaagaaa aggagtggat
    22921 ttcatggaag taaagcagtt gccaaaacga gaagaattgc ctgaaaattt aacttgggac
    22981 ttgaccaaga tcttttcaag cgaccaagag tttgatgaga aatatttgga attatcagaa
    23041 gagttaaaac aatctgaaaa acacaaagga acacttgatc aaggcgcttc tcaattttta
    23101 aatgcgattg aattcgtatt gagggtttat cgccaaactg aagtcattta tgtatatgcg
    23161 caccttaaaa acgatcaaga cactggaaat acagattacc aagcgcttta tgcaagagca
    23221 agcagtctgt tttcgaaagt tagtgaagcc gtttcctggt ttgaaccaga aatattgcaa
    23281 ttgtcagatg accagatttg gcaatatttc aaagaagaac caaaattgga agtctatcgc
    23341 cattatatcc agcaaatagt agataatcga gcccatgtct tatctgctga gcaggaatct
    23401 cttcttgctg gagcaggtga aatctttgat gcttcaagtg atacatttgc tgttttgaat
    23461 aatgcagatc tagtttttcc aacgattgaa ggagaaaatg gtgaaatagt ccaattatct
    23521 catggcgtgt atggtcagtt gctagaaagc acggatcgaa gggtgcgcga agcagcattt
    23581 aaggggttgt acagtgttta cgaacaattt agaaatacat ttgcttctac tttaggcaca
    23641 catataaaag gacataattt taaagcgaaa gtccgtaatt acagctctgc cagagaagcg
    23701 tctttgagca ataatcatat tcctgaaagt gtatacgata ctttggtaga cgtggtaaac
    23761 aagcatttgc ctttgttaca tcgatacatg gaattacgga aacgtttatt agaagtggaa
    23821 aaactgcaca tgtatgatct ttatacaccg gtcttagggg aagctccaat tacctttacg
    23881 tacgaagaag caaaagaaaa agctttagaa gcactgaaac caatgggtga agaatacatg
    23941 gccatcgtag aaaaagcatt ctctgaacgt tggatcgatg ttgtcgaaaa taaagggaaa
    24001 cgaagcggtg cttattcttc gggaagctat gacacaaatc catatatttt attgaattgg
    24061 catgatacgc tggatcagct atttacgctt gtccacgaaa tgggacatag tgttcatagt
    24121 tatttcactc gttcgaacca gccttatgtg tacggcgact actccatctt tttagcagaa
    24181 attgcttcga caacgaatga aaatatccta acggagtatt tattggaaac agaaaaagac
    24241 cctcgtgtac gggcttatgt actcaaccat tacttggatg ggtttaaagg aacagttttc
    24301 cgccagacac aattcgctga attcgagcat ttcatgcata cggaagatga aaaaggtgtg
    24361 ccattgacta gtgaatacct aagtgatagt tatggtaaat tgaatgcaaa atattatggt
    24421 ccagcagtcg aagaagaccc agaaattaaa ttcgaatggt cacggatacc gcatttttat
    24481 tataattact atgttttcca atactcgact ggcttttctg ctgcttcagc actggcgaag
    24541 aaaatactaa accaggaacc agaggcacta gagaactact tggcttacct aaaagcaggt
    24601 aacagcgatt atcctgtgga agtaatgaaa aaagcaggag ttgatatgac acaggctgca
    24661 tatattgaag atgcaatgtc gatgtttgaa caacgtctaa atgaattaga agaattgatc
    24721 gatcgtttat aaggctttct atttttgatt ttctcgaata gaaacgaaaa aaatacgtcg
    24781 gctctcttgt aagggagtcg acgtattttt t
//
LOCUS       DAFELK010000045        24579 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFELK010000045
VERSION     DAFELK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.046"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(153..551)
                     /locus_tag="LP433_002025"
     CDS             complement(153..551)
                     /locus_tag="LP433_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBL2006165.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(548..1321)
                     /locus_tag="LP433_002026"
     CDS             complement(548..1321)
                     /locus_tag="LP433_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL2006166.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1318..2001)
                     /locus_tag="LP433_002027"
     CDS             complement(1318..2001)
                     /locus_tag="LP433_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL2006167.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2168..3055)
                     /locus_tag="LP433_002028"
     CDS             complement(2168..3055)
                     /locus_tag="LP433_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2006168.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3052..3921)
                     /locus_tag="LP433_002029"
     CDS             complement(3052..3921)
                     /locus_tag="LP433_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2006169.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4058..5344)
                     /locus_tag="LP433_002030"
     CDS             complement(4058..5344)
                     /locus_tag="LP433_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2006170.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5617..6195
                     /locus_tag="LP433_002031"
     CDS             5617..6195
                     /locus_tag="LP433_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL2006171.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPMKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6195..7124
                     /locus_tag="LP433_002032"
     CDS             6195..7124
                     /locus_tag="LP433_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006172.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7121..8857
                     /locus_tag="LP433_002033"
     CDS             7121..8857
                     /locus_tag="LP433_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL2006173.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="LP433_002034"
     CDS             complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="LP433_002034"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBL2006174.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9753..10262)
                     /locus_tag="LP433_002035"
     CDS             complement(9753..10262)
                     /locus_tag="LP433_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBL2006175.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="LP433_002036"
     CDS             complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="LP433_002036"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBL2006176.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11563..12654)
                     /locus_tag="LP433_002037"
     CDS             complement(11563..12654)
                     /locus_tag="LP433_002037"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBL2006177.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="LP433_002038"
     CDS             complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="LP433_002038"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBL2006178.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="LP433_002039"
     CDS             complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="LP433_002039"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBL2006179.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="LP433_002040"
     CDS             complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="LP433_002040"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBL2006180.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16617..17591)
                     /locus_tag="LP433_002041"
     CDS             complement(16617..17591)
                     /locus_tag="LP433_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBL2006181.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17572..19455)
                     /locus_tag="LP433_002042"
     CDS             complement(17572..19455)
                     /locus_tag="LP433_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBL2006182.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19473..21698)
                     /locus_tag="LP433_002043"
     CDS             complement(19473..21698)
                     /locus_tag="LP433_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL2006183.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21813..22847
                     /locus_tag="LP433_002044"
     CDS             21813..22847
                     /locus_tag="LP433_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2006184.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22914..23927)
                     /locus_tag="LP433_002045"
     CDS             complement(22914..23927)
                     /locus_tag="LP433_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2006185.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYWGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24005..24193)
                     /locus_tag="LP433_002046"
     CDS             complement(24005..24193)
                     /locus_tag="LP433_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBL2006186.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7065 a         5341 c         4397 g         7776 t
ORIGIN      
        1 agcatatttt gaaaagaaag tctgatgctt agagtagaat ttcataaaaa tttactattt
       61 cataagtatt cacgagaaaa atgcaaacaa aaaagcggaa ataacgctca tccgccttct
      121 tgtttgtgtt tatttcctct tcaaacgctt gtctatgatt cagacttttc tctatcgtta
      181 ttttcatcta aaagttcttg cattccgata atttctcgat attgatgaat cttagtgata
      241 ccaatgactt tgtctacatc aatactaaaa caaataccat tacctggaat atcgatgttg
      301 atgccttgac caatcgcatc cattacttta ttcgtcaaac tatcgggtac taatgtcaac
      361 acaatatctt tttctggcga aatgtccaaa cctaaaaatt tccctgaatc atgtacacca
      421 gaacctcttc catgtaagat cgttccgcct gctgcacctg cttcttttga aaagtcgata
      481 acatcttcgc ccattcctcc gtcaacgatc gtcacaatca tgtgaagatt caatgctaca
      541 agatctttca tttgctttcc cccaattttt gcaatctttc tttttcgatt ctgtcttttt
      601 catcttttcg tttataaata tatcctagta ctaaagtgga taatattggt gtcaatgcaa
      661 tcattgcaac cacaccaaac ccgtcaatga tcggatctct tccttcaatt tgtgcagcga
      721 ttgccacgct cattgataaa ataaatgtcg aacacatcgg gcccgttgct actccaccgt
      781 tatcaaaagc cattgctaaa aagatcttgt ccacttttcg tcctaaaata aatgctagcc
      841 cgtatcctgg gatcaagaaa taataaagag agaatccgac gagcaaacgc cacatagaca
      901 atcctactgc tgcgccgatc ccaattgaaa ttaccatcag catgattttc gatcggattc
      961 tcccctcgct caattcttca acctgtttga tcattacatg aatcgccggc tcagcaaacc
     1021 ctactaagaa ccccattaaa aagccaaggg gaaccagtat ataattgtaa ggcaatcccg
     1081 caatagcact gcctaaatgc tgtcctaccg gtacataagc catattgact ccgtgcagga
     1141 aaaggatcaa cccaatagtc gttatcaaga aacctttcat aatgtcaaag aaacgctttt
     1201 tgcgcatacg aaaactaatg atattcatta aaacaaatag gattacgata ggtgccactg
     1261 ccaaaatgac ttccatggta acgatttcga ttccatctat cacttgctgc cagaaactca
     1321 ttggaagatc acccccaaaa tcatcacggc aagaatcggc cctaacgaag caataccgac
     1381 cattccaaaa ctgtcatttt catttttctt ttgtttgatc atactagtca tccctccggc
     1441 aagggccaag ataaatggaa cagttactgg accagtagtc actccccccg aatcaaaagc
     1501 aatcggcata aattcggaac tggtgaaaaa tgaggcgatc aaaacgccta tgtagcctat
     1561 agccatcaat tgataatagg atagcttgaa tacgacccga agcagcgcaa aggctagaaa
     1621 tactccagtg ccgacgctga cgatcccaat cagcaacact ctgccaatct ctccgtcaga
     1681 tatatcatat acttgttgtc ccaaaacttg cacggaaggt tcagcaatcg tgatcacgat
     1741 cccgatagca aatcccaaac tgaccaaaac ggtcaaactt ttctttttga tcatatattt
     1801 ccctactaga tctccgactt ccatcataga ataatctgct ccaaacaaaa agagcgtcat
     1861 tccgatcatc atgattgccg caccaaccag aaatgaagcg aggtcttctc cttctaacgg
     1921 tgcaaaaaca aacgttaaaa tgacaatcag gacagtcatc ggcaatatag cagcaatcac
     1981 ttctttaaaa ttttttagca tgtatcctcc tcctttactc tttaagttta ccttaaaatg
     2041 aaagagtttt cgagcacaaa cttaaaacgt tatcatttaa tttttctcaa cataaaataa
     2101 cacacgtccc aaaagtatct ttttacttgg aaaaatgact ttgaaggaac gcgcttattg
     2161 tgttttttta ttttacagag ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa
     2221 atacgatggc agttggtaaa gtagcgatga ctaatccagc catgatcatt ccatagtctg
     2281 gtgtatagga agcacccata gcagataaaa caagcggaac cgtccgttta tcaggagatt
     2341 gcaaagctac taagggccat aaataattgt tccagctact catgaatgtg atgattgcag
     2401 ccgcggcata ggtattttta gccgtcggca tatacactct aaaaaaaata cttagttctt
     2461 ttagaccgtc taatcgagcg gcttctacta gatcttttgg aaaagattta acattttgtc
     2521 gaaagaagaa gatcaaaaaa gcagtgctaa cagatggcag gatgacaacc aagaaactgt
     2581 tgattcccaa aaccgttccg ttcaattgtg aaaacattcg atataaaggg atcatcaatg
     2641 ccgcaaaagg aaccatcatc gatagcagta gaatattgaa aattaggtct tttcgtttac
     2701 tttgataaat ctcaaatcca tatcctgcca ttgacgaaat cagcaatgca aacacagtgg
     2761 tcaccaaagc gatcatcgct gaattccaaa gggaacgagt aaaattcagc tcattggaaa
     2821 acaaattttg aaaattgatg atcaagttac tgccaatctt tatttttccc gatgtgatat
     2881 ccacgggtgt attcgtcatt cccaaaacca tccagacaaa agggaaaatg gaaataaatg
     2941 ataggatgct taatgctgta tactttaata ctgacccaat tgtcgaacga agttctaatg
     3001 cttgtttttt gacgttgggg cgttcgattg tttctttttc taccatattt ttcatcgact
     3061 ttctcctcct actttcgttt ggattatcga caatatcaca ataaaggaaa caataacaaa
     3121 ggaaactgct gccgcatatc caaaattagg cgtgaattta taactcaaat tatagatgta
     3181 ttgagatagg gtggtcgttg catttgctgg tcccccgcca gtaatatttt gtacttcatc
     3241 aaaaagctgc aatgtcccga tcgtcgaagt aatggaagta aacaaaatga ttggttttaa
     3301 atttgggatc gtcactttga taaactgctg ccatttagaa gcaccgtcaa tagatgctgc
     3361 ttcataaatc tccgaatcaa tattttgcat gcctgaaagg aaaaaaatca tattgtatcc
     3421 agtccaacgc caagtgatcg aaagaatgat cagaactctc gcccaaattg gatgagtcaa
     3481 ccagccaatc ggtgtgtcaa tcataccaat gcccaacaac aagttgttta caaggccaga
     3541 ttgagaaaat agacttttca tgatcagaga ataactgacc atcgaagtga tacatggaag
     3601 aaagatagcg gttcgaaaca accctttata tttcaacttt ttatcattta aaaggttgga
     3661 aataaaaagt gctagaaaca acatgatcgg tacttgtaca agtaaataca ggaatgtatt
     3721 aaaaaaagct tttttaaaag ttgcatctgt caacatccgc tgataattac ctaacccgtt
     3781 aaatgtcata ttgacagggg gaccactttg aaaagacgtg atcaaagcca aaaccatcgg
     3841 aataaaaacc atgattgata tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt
     3901 gaataaatct ttctgcttca ttcttttccc tccaattcta tcattgatta tctacatgaa
     3961 aagacaagaa agacaatatc tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct
     4021 gatgaaaaag cgaagaaatt cactttttta ccaccgatca attagccaat tgtgcttcta
     4081 cttgtttttg tgtatctgct agtaccttgt ctgtctcttc tccattgatg attcgatgaa
     4141 gagcttcagc tacgactgct tcaattgcat aggtctcatg tccgtaattc acttctggta
     4201 tttcagatgt ccatgttgaa aaatcgtcaa agatcttttg accactgtaa aattcagaag
     4261 cttcttgata agcttcttgt tcattcgcgc taagcatcgt agatactagt ccgatttctt
     4321 tcgcaagagt gcccatcagt tcttcattcg aagcaaacgt tgcttctagg aaatctttcg
     4381 ctgaatcttc tccagctact cctttgatca cataccagcc agcgccgcca aggttagaag
     4441 cttgcgcttt ttgcagattt tctggaagtg caggtattgg tgcaatcttc cattttccag
     4501 attggttttc tgctccttgg atcgttgaag aataccaagc gccagttggg ctagaagcta
     4561 ctgctcctga ttgtatcgca gttactccag cattccagtc agaggtttgt tcgactagat
     4621 cttctttcaa aagagtggca aacaattcaa gaccatactt taaagatgca ttgtcttgga
     4681 tcgtgactgt ctccccatct tcagatgtat accattctcc tgcctgttgc ataatcatcc
     4741 ttactcgacc aaggtcagaa ggattgactt cagcgatttt ctttcccgtc ttttctttga
     4801 catctcgcgc tacttgaata tactcgtccc acttcagatt ctccatatcc tcttctgtat
     4861 aacctgcttc tgccatcaga tccgtacgat agaagtttgc tgttacgccc gaatcgaaag
     4921 gaacaccgta tattttatct cctactttgt ttaccgcaaa tttatacggt gcaaaatgat
     4981 cttcctttac aatagcagac aaattagcga atgcatctgg ataagaagtc aaatagcctt
     5041 gtatcctata atcttcaatc aagacgatat tgggcaatcc ttctgtattc ccgctcgcta
     5101 aagcggtgtt cagtttctga acgatatcat cctgagacat cgtaacaact tctatctctg
     5161 tttcttcgtt ctcataaact ttttttgctt cattcactgc tttgatattg aatgtctcat
     5221 cccacgccca gacagtgact ttttcttctt tgtctgctgt actactagca cttccgcatc
     5281 ctgttaagaa acctgatgct gccgctaaac aaacgactcc agcaattaac tttctgatgt
     5341 tcatttttat ccgctccttt tccatccatt agttgtttac gtttgctaca ttcatcatac
     5401 caaaatttga aaacggtttc tttattattc agatacttca aaaatttctc ctaaaataat
     5461 aaaaaaatac aaatcaacta tgacaaaagg aataatctta gcatctagac caaagatcga
     5521 aatggtgagg tttctttaaa ataaaaatat ccttgcattt tctcctagaa ataagtattt
     5581 ttaaattaca agactattct taaggcgggt aaaaaaatgc caatacgcgt aattcttatc
     5641 gatgatgaac agacgatttt agatggaatg aaacagttga tcaattggtc tgagcacggg
     5701 tttcaattaa tagggacttt ttccagtccg atgaaagcgc ttgatttttc tttggtacat
     5761 gcaatcgata tcgtggtcac agatgtaatg atgcctgaat taaatggaat cgaattatcg
     5821 cggctattaa aacagcaaca acctgaaaca cagatcctta tcctctctag ctatgatgaa
     5881 tttgatatgg ttaaagattc ttttaaagaa ggcgtcgctg attatctttt aaagcctcga
     5941 ttgagtcctg atttttttct aaattcctta actgccgttt cacaaaaaat caaaaaaaag
     6001 cccaacaaaa gcccaatcac caatcgttat gagcagatct gcgagaatct ttcacagcag
     6061 attgctggac aaactcgtcc attgcttgac cctcttcttt ttgaacacac cttgtttttc
     6121 tgttatatac cgaaaaacgg ccattcagtt caaaacaagg ctctaaacaa aaacagtcga
     6181 tcacccattc attgatggat agcgacgatt cgtttactat ttatcctgtt tctacctttt
     6241 cggaagaatc cggctatgta atcaatactg attccaaaga tacacttagg aagtttgttc
     6301 aaaagtttcg tcaagaagtt tttccaggtg atttttttgt tgtttctgat tcttttgcaa
     6361 tccaagatat caatgaaata ttccaagaga tcagaaattg caccaaagga caacgtttct
     6421 atcataaggg aaagaacctt gcttatcagc atgaacttct tccgttatta accaaccacg
     6481 agcagcaagc aagtagttat ttaacaaaaa tcgttcataa agactacgct ttagctgtca
     6541 aagaacttga gaatttcttc acgacgatat tggaacagcc tattgatcca gcttatttga
     6601 aacatgaggc aatcaatcgt ttctatgcat tactcaacgc tttggctgac gagcatgttg
     6661 ggaatgaaga actttctttg ctcaagatcg cccttccttc tttattagcc gatgctgagt
     6721 atttcgaaga tttttctatt cttgtcaaag aaacacttga gaaactcacc cacttttctg
     6781 caaatgcaaa aaaagacaat ttcgatatct tgactttgat ctacgagttc gtccaggaaa
     6841 attatgagaa agaaatcaat ttacaacttt tatccgaaaa atatcatttt tcatatagct
     6901 atctctcagc catctttact gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag
     6961 tccgtatcag taaagccaag ctctttttga cggaaacacg gcttactttg acggaaatct
     7021 gtgagaaagt cggctatacc gaactgggtt atttctccag agtttttaaa gaagagacag
     7081 gaatgacacc ttctcaatac cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga
     7141 gcatgaactc tttgccaaac ttctgttcat tttgttcatc ggtctttttc tgcaagccat
     7201 cgtcatttct ttgtttattt atcatcgatc aagggatgcc tatatccagc tgttcaatca
     7261 atcgaatgat gtggtactaa aaaagattca atctgaattt gaaagtttga atgatacaat
     7321 cgagaataca ttagccgctt ttgattctaa tccagctgtc aaaagctatt tttccaatga
     7381 tccagcccaa catatggaac agcttcagca actaagaaca atccaaaaaa tgaatgactc
     7441 tctttcaaaa atccatccaa tgatcgatta cgatgtattg atctttggag aaaatggaag
     7501 aacttttgtc ggaaacgaca tgctcactgc cgtatctgcc gattcttttt ttcaatctgc
     7561 gattgctcag agagtgaatg aacgtgctgc tgatacacaa atgctttttg cacaccacgg
     7621 attgactctt cgcgataaga aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac
     7681 attgaatcac gtttacggat atgctgtttt atcgatctca tccaagcaac tagcgaatct
     7741 ttttcaatct gtagtaaatc ctgagatatc gaagatctcc ttcatgaacg aagaacagac
     7801 gatcatcgca tcaaatgaag aaaatacaat tgggagccga tcaatgattt tcaaaaaact
     7861 aacagtaggt gaaacaacga tttcaaatgg acagcagttg acccgtcttc ctctgtaccg
     7921 ccaggattgt acattactca gtcaagtcga tcttcattct ttatctaacc aaatgggcgt
     7981 gatttttccg attattttgt ataatatcgt gacacttgct tttgctggct cattggtatt
     8041 tatgtatttg gatcgacaca caaaatcgat ctaccgcttg attgattcgc taaaacggct
     8101 agaggaagat ggcttaaaag ctactgttcc tgtacaagga agccatgaag tccaattgct
     8161 agggaatacg atcaatcaat tgctaagtaa tgctcagcat cattatgaac agacgatcca
     8221 agacgaaaag aagaaacgtt cgcttgaaat ccaaactatg caagcacaga tacagcccca
     8281 ttttatttat aatacgctga ctagcttgaa atttttgatt tggcagaaaa aaacagatga
     8341 agcagttcaa ggaatcgaca gtttcattac tttactaaga agtacgattg ggaaaaaaga
     8401 agaagtgatt ccagtcaagg aagaaatcaa aagcgtacaa agttacatcg atcttttgag
     8461 tatgcgatat ggcgaaagaa tctcggctaa aataatgatt cctgatgaac tgcagtcatt
     8521 atctatgccg aatatgatcc ttcaaccaat tatcgaaaac gcctatcttc atgcttttca
     8581 caataaaacg caaggattca tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt
     8641 cgaagtgatt gataacggcg atggcttcga tactgaaaat accaaacaaa aaaatgatca
     8701 tttttcagga atcggcatca gccatgtaga tgagcggata cgcctaatgt atggcgatgc
     8761 atatggctta acgatccaat cagtgattgg gacaggaacg actgtaacga tttgtctacc
     8821 gcttcttcct aaaaatcaat cagaatatca aaaataaaga atagccaagc gctgattttt
     8881 ttattttaag ttaaataaat caatcagtat tcttgacttt catctacgcg tctcttctac
     8941 tgtcagcact ggataacagc ccaatatttg actttctcct ccgagcatct tgatttcttg
     9001 gagcgcattc tctactaatg tcattggacg gtccaacaac aaatcgatca cgaaaaaata
     9061 ttctcccaag ctagttttca atggtcggga ttcaatctta cttaagttga tttcccgcca
     9121 gccaaaagct gccagcattt tatgaagcat ccctggccga ttagcaggta gtgtcaagat
     9181 gacactcatt tttactggag ctgactgctg gctggtcatc tttcggtcac cgacgatcca
     9241 aaaacgtgtc tggttcaact cattatcttg gatattctca gctaagatct ccaatccaac
     9301 atgctgtgct gtttctaatg aagcaatcgc tgctgcgtct tctttcggat gttctgctac
     9361 atacattgct gcagcagttg ttgattctgt tgctactaaa ggaacattag gataatgcgt
     9421 ttctaaaaac tgttgtgatt gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt
     9481 tgttgctgga ttgcctaaaa gctgctgctt gataggaaga acgatttcac ttttaacttc
     9541 gacttctgga tgtttggaaa gaagatcgat tgtgtgatga acagctcctt ccaatgaatt
     9601 ctctacagga acgacagcca gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg
     9661 gatggaagca tacgcagtca attgttctgt aggaaatagc tgacaagccg cctgataagt
     9721 gaatgaactt tctggcccta gatagctgac gttcatatgc ttttgatcct ttctataatg
     9781 gtatcgatga tcttttctgg tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct
     9841 tcataccaag aaagtcgttg tgccaataat gcttttattt cttctcttgt ttttccaaga
     9901 gctaaaggtc gaatagacgt ttcatcttgt tggatacgat caactagaca gtccgcttct
     9961 gcctctaagt aaagaacaat cggctgtgtt tttaaaaaac gccgattttc tgcactttgg
    10021 acaatccctc caccagtcgc gataattttg tcttcatttg acagctttct taaaatatct
    10081 gactccactt ttcgaaagct tttttcaccg taatagtgaa aatattcggc aatcgacaat
    10141 tggatatgtt cctcaatctt tgtatctaaa tctacatact ctttttgtaa acattgagct
    10201 aaccctttac cgattgttgt ttttccagcg cccatgaaac caatcagcaa aatgctagcc
    10261 atgagcttct cctcctgaca caagttctgc taaatcgtca aaaaatgccg gataagagat
    10321 tgaaacagct tcagctcctt ctagttcgca aggtccatca gctatcaaag cagctacttg
    10381 cagcatcata ccgattcgat gatcgcctct gctggacact tttgcgccat gcagaggtgt
    10441 cggcccatgg atgatcagac cgtctgctgt cgcttttatc tttgctccca ttttctgtaa
    10501 ttcttctgcc accgcatcaa ttctgttggt ttcttttact tttaattctt ctgcgtcttt
    10561 gatgatcgtg attccttctg cttgagtagc cactaaagct agaatgggca attcatcaat
    10621 cagacgcgga atgatttctc caccaatcgt tgctttcttc aaatgactcg tcttgacact
    10681 taaatcagcc gattggttct gttcattgtg attcgtctgg gtaatcgctg cgcccatctc
    10741 ctccaacaca tctaagatac cagttcttgt tggattgacc ccgacatttt ttaacaacag
    10801 ttggctttcc ggaacaagaa gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc
    10861 tggaacagtt atctgttgac cagttaattt ttgcggtccg gtcactatga tcgttttatc
    10921 ttccactgtg atccttccgc caaattgacg aatcatttct tccgtatggt tacgggaacg
    10981 ttctttttca acgattacgg atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga
    11041 tttgacttgc gcactggcta caggcatatt gtatcggata ggtgataaag agcgggttcc
    11101 tgtcacagtg attggtagat actggtcatt ttcttctcct tgcaagtcag cgcccatctc
    11161 gcgtaaaggt tccatcactc gccccattgg acgtttagac aacgaagcat ccccgaacag
    11221 agtagtcgta aaaggctgtc cagccaaaat acccatcaat aaacgtatgg tcgtaccgga
    11281 gtttcccatg tcaattgatt cggttggttg gacaaatgag tggctaccgc gaccatgaat
    11341 cttgatcacc tcttcctctt cttcgatctc gacacctaat tgttggaagg catgtaaagt
    11401 actcagacaa tcttctgcgc gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc
    11461 tccaaacatg atgctgcgat gggaaattga tttatctgct ggtatcctaa cagtccctct
    11521 taatccatgt atttgttgta ataattgcat ttatccagcc tcctatttga tccagcaatg
    11581 ataactggta ttagacataa tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa
    11641 actgatttgc agtattccta aaatatcttc cctggtctct tggatcttca aattaatcaa
    11701 agaaactccc gcttttccga tcagtccagt tacttctgca ataacgccag gttcatctgg
    11761 cacatcgata aataaatcaa aaaaggcagg aatcgcgcct tgcttatgga caggcaactg
    11821 gtctcgactt tcttttgccc gattgaaaaa agaaaagatt tccgattggt tctcagtcat
    11881 gatccattct gctatttgtg tcatttcttg ttgccaatct gccaatcgtt ccaataatat
    11941 ctgcttattg ctcaacaaaa tatctgtcca catgacagga tctgaggaag cgatcctagt
    12001 gatatctcga aagcctcctg ctgccagttg tttggctcgc ggatactctt gattgaattg
    12061 ttctgcctga ttgactaagc cagctgccag aatatgtgga aaatgactta gcattcctgt
    12121 tatacggtca tgttctcttg ctgtaagagt tacatatttt gctttggttc cgcaaaatag
    12181 ttcttgcagt ttttcaacat cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc
    12241 attttcaaat agtttagcat ctgctgcctg tatacctgat ttatgagaac cagccattgg
    12301 atgtccaccg acaaaccgaa gatttttctg ctcagcggat gtcacgactt gctgcttcgt
    12361 actgctgaca tccgtaatga tgacgtgatc agacaagttg attctttcaa ggacatcaag
    12421 ataagctaag gttgtacgga cgggaacggc taataagata acgtctgctt gttctgcacc
    12481 tgtttcaaaa tcacttgcaa cgtaatcaac gatctgctgt tctactgctt gctcacgggt
    12541 ttttgactga ctatcccaac caactactat cagttctgga ttggtctgac gaatacaaag
    12601 tgccatagaa gcaccaatca gtccaagccc cacgataaaa acatgttgtg ccatcttatt
    12661 tgcccccttt ttagtaatgt ttcaagtagt cacggtactc cttcactgca gctttcaact
    12721 caacaagcga atcacttggg aattttgaca atagctctgt cgctaccaca gtggctacaa
    12781 cattttccgc aacgacgcta gctgcaggaa ctgctgtact atccgaacgt tctacacttg
    12841 ctttgtaagg ttcttttgta tcgatatcaa cactttgaag tggcttgtac aatgtaggaa
    12901 tgggtttcat gaccccgcga atgacaagtg gttcgccatt ggtcattccg ccttcgaagc
    12961 cgcctagatt attggtacgt cggaaatagc ctctttcttc ttcccatagg atctcatcca
    13021 tcacttctga gcctggtaat gaaccagaag tgaatccgac cccaaattct acgcctttaa
    13081 aggcattgat actaaccaca gcttgtgcga ttttggcatc tagcttcgtg tcccattgta
    13141 cgtagcttcc taatccagct ggaacgcctc caacgagcac ttctacaatt cctccgatcg
    13201 tatctccatt tttctttgtc tgatcgatca aatcttttat tctttgctca actgctggat
    13261 caacaactcg tacttctgac gcttcagaaa tttctttgat ttcttgaatc gagatatttc
    13321 caggtatttc tgcttggatt ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa
    13381 gttcttccag aattttcttg gcaattgcgc cgattgctac acgcatggtc gtctctcttg
    13441 cagaggaccg ttcaagcaca ttccgaagat ctcgatgatg gtatttcata ccgcctacca
    13501 aatccgcgtg tcctggacgc ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca
    13561 cttctgctac agacatgaca gttgtccaat ttttccaatc tttattttct accactaaag
    13621 tgacaggtga accaattgtt ttgccgtgac ggatgccaga cgtgatccga acacgatctt
    13681 tttcgatctt catccttcct cctctgccgt aaccagcttg tctgcgagcg agttcgtgat
    13741 tgatttcttc ttctgacaga ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt
    13801 ctggtccatg ggattctccc gcagtcatat aacgcatctt acagtcctcc taagtaatct
    13861 ttgaatgtct ctgtgggaac aggaacgatt tttgcttgcc caatcttttc tagcaagatg
    13921 atattcaatt ggcttcctct tgctttctta tcatgggtta tcgcgtggaa taattcatct
    13981 ggatgactta gatcgtacgt aatcggcaga tggaattttt gaagtatcct ttctaaagca
    14041 gctgtcgatc cagttggaga caagccgatt ttttctgcat gagaagtgat ggctaccatt
    14101 ccaatagcta ctccttctcc atgactgact accccatatc ctgctgtatt ttcaattgca
    14161 tggccaattg tatgaccaaa atttaaaata agtcgatttc cttggtcaaa gacatcttct
    14221 tccactactt ttcgtttgat ttccaacgta gcagtaatga ttggaacagc atgttccaga
    14281 agatcttttt cgtctttcag ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct
    14341 gctgatttga tgatttcagc gattccttct cgtaaacgac gtaccggcaa agtttttaga
    14401 acctcaggat caatcaatac accagctggc tggctaaatg ttccgacaag gtttttcgct
    14461 ttgtttgtat tgactgctgt cttcccgcca atactagaat ctacttgtgc aagtagcgta
    14521 gtcggaattt gaacgaaatg gatcccacgc atgaacgtcg aggccacgaa tgctgctaga
    14581 tcacccacca ttcctccacc aagtgcaagt atcccatcgc tgcgggtaaa atcattatct
    14641 gctaaaaaat cgtataactc agctgcttgt tctaaagatt tactggtctc acccgccggt
    14701 acgattgaaa ggactggttc aaaattagct tgtctcaatt ggaacatgat tttttctgca
    14761 tatagtggag caacgtttgt atcagtgatc acagctactt tttgaggtct ccaaatcgtt
    14821 tgaagccatg atccagcctg ttctagtgcg cctttttcaa tatgaatatc gtatttttgg
    14881 ttatcaacat gtacagtaag cattcgtttc acttctttct tttaaaaagc tggaattaat
    14941 cgagtgtctg aatcttttcc attgcttctt tcatgatcgc aacttctttc atcatgcgtg
    15001 agtaagtctt ttcattcaac gattggggac cgtctgacca agcatttgca ggatcaggat
    15061 ggatctctac gatcatgcca tctgctccgc ttgccacacc cgcacgagcc attggtggta
    15121 caagttccca aattcctgta ccatgacttg gatcaacaat cacagggaaa tgagttaatt
    15181 ttttcatcaa tgggacagca cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc
    15241 gaatcccacg ttcgataaaa atgacaggag atttgtcttc gactgcaatg tattctgcag
    15301 cattaagcca ttcattgatc gtaccggaaa ttccacgttt caatccaaca ggtttacctg
    15361 ttttaccgac agcagatagc agtttaaaat tttgcatatt acgtgcgcca atctgtagga
    15421 tatcgctgta ctcagccacc atatcgatat gcccttcatc catcacttca gtaatcactt
    15481 tcattccaaa ttcatcagcc gcttgacgga tgtatttcaa tccttcttct tctaaacctt
    15541 ggaaagcata tggagaagta cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc
    15601 cggctttggc cattcgcgca cattctctga tttggtctaa tccttcgata gaacaaggac
    15661 cagccatcgt cacgaaactg ccgtcaccaa tttttactcc gtctacatcc acgactgtat
    15721 tgccaggatg gaattctcga gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt
    15781 ctactccttc atagcgtgta aatgctcctt cttgtaaact tcgcgtatca ccttttagtc
    15841 caatcactac tcgttctgtt ccttgatcga ttgagacttt gaatccttct ttttcgatat
    15901 gatcgacgac tttttttatt tgttcttccg ttgcttcttt tttcataatt actatcattg
    15961 tttttcccgc tttcttttgt ttacttatct atcttggctg attttctcta ctttttcaag
    16021 gtggttttac attaattcct actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt
    16081 ctttcctact tatgacccag ataatcaaca aaaaaagatg tccctgtagg aaattgcctc
    16141 tacagtgaac atcttcaacg agccttaaaa agcgctgcaa aaatataaaa tagccactat
    16201 agatgaattt ctctacgtgg ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac
    16261 aaacctggtt tgtttgtacc cacgaagtca tgaatacaaa cctatctaaa atagctaaag
    16321 taatacgtat tcagttttgt aagttttcta gatttcataa aaaatcgctc caaactgatg
    16381 taagaattgt acctagtata gacataaaaa aatcgactgt caatcatttt tatgaaactt
    16441 tttttaattt tctgatagtt aactttgttt ttcagaaaaa taacaattgg ttttattgaa
    16501 gaaaatagtc atgaacaaaa gtatctgaga acttttttac tctcttgttc atgacatata
    16561 gaataaagca gctttgtctt gtaaactccg tttttcaaat aataatctaa agattgctac
    16621 tgaataataa agccgatttc atggtcctct tcgctgctga ttcggtaagg tgactcaaca
    16681 tccgctcccc agctattgat acccccgact cctcttactt ttgcaaaaat cgtaagaacc
    16741 gttcgtcttt ctggcggtag ttcttctata tgtgttgcct gttccagttc ttctgctttg
    16801 aatggtaaag cggaaaaagc aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct
    16861 tcttgatctt tatccgtatt atccaacgtt tgatttcttg ttagttctac ccatttcgtt
    16921 tccatatgca tgccgcattc ttggggaaca aggtatgggg aaacggggag tcctgccact
    16981 ttataaatac cttcgacacc accagccatc cgatccggat atgtttcccc tgataggcct
    17041 tcatactcaa aaaattttgc tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat
    17101 tccggtaatc ctttttgtcc ataataatgc atattgacaa gcattttacc ctctccagcg
    17161 atttggtagg aaattgtcac ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg
    17221 atttcaaccg tttcagcgta ttcattactt gaatattgat tatttactgg agcaatcggc
    17281 aaatcgatct ttttattgtc caccagtact tctatttctt tgacttttgg atacaatccg
    17341 gctcctaacc acataccgga tttaaatcca aatccgctac ctctgtcatt atcggtcgtt
    17401 gctcgccaaa aaactggaag tgtttcccgg tatagccatt cttttccgtt tttattgagc
    17461 gattccagtc cgcctcttgt ataagaaaaa atataatgcg tattccccga tttgacacct
    17521 aatgtacagt cgccgaagac gattgcaact ttttccgtat ccatatgact tttatttact
    17581 gtatttttca taataatatc ttacctcctg catggcgggt ttttcttgtc catctgcaaa
    17641 aacgatccca ttccctgaga attcatagtc acttggttta tcgtcaaagt caccgccata
    17701 gcgcatcact tctctgcctg tgattggatc agtcacttgg atcgcctgat ctttaaaatc
    17761 ccatatatag cctccttggt acatttcata acgatcaagc aacgtcatgt aagaatccat
    17821 tccacctaac gaattcccca tgtcatgcat atattcacat aagatgaacg gtttttccgc
    17881 tttattttca aggtagtcaa tgatctcttc tggtggcgca tacatgcagc tttttacatc
    17941 tgaaatcgaa tcttcgaatg ctggatttgg aaaattccct tcataatgga caagtcgatc
    18001 ggggtctact tttttgaagt aatcgttcat ttgtcgaatg ttttcttccg cataagattc
    18061 atttccaaga gaccaaaaaa gaatacttgg atggtttttt aatgtttcga aattcgtttt
    18121 tgctcgatca agaacagccg cctgccactg aggtactgca cctggtacgt tgtaagaagg
    18181 ctcaaatgcg cccatttttt gccatgagcc atgggattcg aggttcgttt ccgccatcac
    18241 atggattcct gcttggtcgc ataaataata ccaagtgatc tggttggggt aatgagatgt
    18301 ccgtacgccg ttgatctttg cattttttat gatagccaaa tctttttcca tatcttctat
    18361 agtgatggcg cgtccttttt tcggatgcca ctcatgtcga tttaccccgt tgataatcat
    18421 ccgttttcca ttgaagtaga tgattttatc tttgatttcg attttacgaa aaccgaagga
    18481 atagtcaata tactccgtta ctcttttttc ttcgtctatc gtctccaatt caagcttata
    18541 taaattgggc tgaaaatgcc cccacagtgc cacattttca aatccatcga tgcgaatcgt
    18601 catttgctct tttaacggat attgctgttg atagatttcc ttcccatcag gatctagtat
    18661 cgctacattc agctgactgt ttttggctac ttgctcaaaa gacaaatcta cttcaagttt
    18721 gccattttga catttgtcat ctaagcgagg tttgatccaa agatcttcta aatggttttg
    18781 tcctcgagca actaagaaga catctctgaa gatcccaaaa aatcggaaaa agtcctgatc
    18841 ttccaagaat gcagctgtac ttcttttgta aacctccaca gctagaatat tttcttcttc
    18901 caaataaggt gttaaatcaa attcagacgg agtgaacgaa tcttcggcat acccgataaa
    18961 atgaccattc aaccaaataa acattgcttg ttctacacca gcaaaatgaa tcgagatttg
    19021 ttttcccttt agaccttctt ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc
    19081 tttagcagct gaaaagatcc cttccgcctc tttctcaggg cttgtcgtga aagggggacg
    19141 gcgaaataca tgtccctccc acggatacat cgtattgatg taatggatct tgtcataatt
    19201 tgctaattca atatgactag gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt
    19261 tttataaaat gtttttggtc gtaccgaagg atttggcgaa taacaaaaac gccatgatcc
    19321 atttaaagac tgtttaaggg aggatgtggt ttctacttct tcccttgttg cataacaaac
    19381 atgatcgcta tgtgcatttg attggttcac tctaaaaact tgtggatcat ctaaccattt
    19441 tatatttgct ttcatacttt tttccttctc tctcataact ttttgaaatg aagcagttct
    19501 gtttggaaat caccttgaaa atcggggaag taaagtccaa ctgtcatcaa ttcggccccc
    19561 gaaaatatcc gcttcgaggt ctgttcctga taaagtgcct catcatctaa ccccatcaga
    19621 tatacttcat ggaacgctgg ttgagctgaa gctagtatcc tccctaaaaa cacaatagct
    19681 tcatcttgtt taggagacac aaacatccat gcggcaatat tttcttcaaa aggactcgcc
    19741 aaacgataat aatggccata ctggatcacc ggacgaatcg tttgatagga tataatttgg
    19801 tcttttactt gctttttttc ttcaggagac agctttgtca aatccagttc ataaccaaaa
    19861 acagcgctca tagctgtttc tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga
    19921 tttggtacag ctgatacatg agctgtgatg gacgaaatcg gataagcaag gcttgttcca
    19981 tattggattt tcatacgctc cactgcatcc gtgttatcac ttgtccatga ctgcggcata
    20041 taataaataa acccggcatc aaaccgtcca cctccaccag aacagccttc ccataagatt
    20101 tccggataat cagttgtcaa atgttcaagt agttcataaa gcccgagcat ataacgatgc
    20161 gctacttctc cttgtctctg tgggtcaagg gtaatcgaat agacatctga aagcgaacgg
    20221 ttcatatccc atttgatgta gtcaagagga atcgtatcta aaatctttct catttgtttc
    20281 tcaatcgtct gccgaacatc taaccttgta aaatccagta catgttgtga tctggaagca
    20341 gaaggcattc tacctggctc ctgcataaga aaatcaggat gtgttcgata cagttcagaa
    20401 tcaaccgaga tcatttcagg ttcaaaccat aaaccaaatt tcaatccttt gctatgagca
    20461 taatctgcta tttcacgtaa tccatttgtc aacttgcctt catactcgaa ccagtctcct
    20521 aatgaagaat tgtccgcatc tctttttcca aaccagccat catctaatac gaacatttcg
    20581 atgcctagct cctttgcttc atcaatgatc gccttgattt tttcactatt gaagtcaaag
    20641 taagtggctt cccagttatt gaccagaatc ggccgttcag caaattgatg acgacctctt
    20701 gcgattcttt cacgtagcaa ctcatggtgg atctgactca ttttgttcaa tccctgactt
    20761 gagtaagaaa ggatcatttc aggtgtttga aaagactggc ctgcattcaa ttcccacgaa
    20821 aaacgatggc tgttgatccc accgacgact ctcaattgat tgatctgatc tttttcaagt
    20881 tcgaaagaat ggttgccgga ataaacaaat tgaagtccga tcgcttctcc agtattttct
    20941 gtcgtatgat gatgaactaa agcaataaag ttattcatat ggtgactgct cgttcctcga
    21001 cggctttcaa atacttttgt tccagataaa acagattgcc gtgaaatctg tctttcattg
    21061 acatgtgctc ctggcaaagc aatgacttca tcaaatcgcc tagtatgggc aaagtctagc
    21121 tggaaactag ccgctttttc tagtttgatt gtttctccgg tttcatttct tatctttaca
    21181 gatcgtgtga tcactgctct atcagtaaat atggtataga acaaatcgaa ataaatcgct
    21241 gtttctctat ccttaagtga aatcaccaac gtttgtgcct ctgacttgtc catcacataa
    21301 gtttgaggca agccttcgat ctctggcttc ccatctgtaa tataatggct gtcatatctc
    21361 agatccagta agtctgatcc attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc
    21421 atgctgccat gagaagagta ttcttgcggt agtgtatctt tcgacagaga ccggtcagga
    21481 tttaagggaa catttcctga aaatccacga tctcttcggg gataattttt attgtctttg
    21541 tactgcttga ctggtttgcc aaaataaata tgcgccaata cattgctttc ttctatcttt
    21601 atcagataag aaagaaatgt atttcgtaaa tggaagactc ggctcttttc atcaaataag
    21661 atgaaatttt tatctgtttt tctatgcgta atatccatca tttcactccc aacaaaacgg
    21721 aaaccgttta ctttttttta taattcctgt atactgttta ctaaacaatt ttgtcaataa
    21781 aaatttttta tttttttgag gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa
    21841 aggcaaatgt ctctcctgct acagtttccc gtgtgttgaa taacgatcag acgatccatg
    21901 tggctcagac tactcggcaa cggatagtag aggcagctgc tgcgttggat tatgacatca
    21961 gtactcgtaa atatatcaaa aagagaatgc cttcgattgg tgtgatctct acgatcggca
    22021 aagcgagcga agaacaggat atctattaca aacatttgcg agtagggatg gaagaagaag
    22081 ctcgacgtct gcatttaggg atgaatcgaa tctataatct atctgataat cctaaacaat
    22141 gggaagatct agatcagtta ggtgcggtga tcgttgttgg gactgttacg aaagaatcga
    22201 ttaccgcctt gttaaaacaa aacatgcaaa tagtcgtcgt ggataaccct gacatccagc
    22261 aagaggtcga tatggtgtat gcagatcttg aacggatgac taaaaccgta ctggaattgt
    22321 tcttagaaaa tggtcataaa agaatagcct atatcggggg atataaagtc gatatggatg
    22381 aattcggtgg gaagcagatt tctataaatg aaaagaggat gcgtgcctat cagcatttta
    22441 tgatcgatca tcacttagaa aaatatatgt cttatcatct aggtggctgg acagaaaaac
    22501 aaggtgaggt acttgcgact aatctattag aaaatgaatc ccctcttcct actgccattc
    22561 ttgtcgggag cgatccaatg gcaattggtg tctatcgggc attgaaacaa aaaaatatcc
    22621 aaattggaga agagattgtt gtagcaagct ttgataatat cgagacaatc gcaaacctct
    22681 cccctggctt gaccagtgtt caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa
    22741 tggcattgga gcgaattgac ggtatacggg acgaaccaat cattttgact tatcctgcac
    22801 gattgattgt tagggaaagt tttatcccaa gaacaaaaag gtattgaaag agaggttgtg
    22861 aaaagccgct tcgtttcttc atactcaaaa cgaaacggct ttttcacaac ctcttactta
    22921 tacttattca caaaatccaa tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa
    22981 tcaaattggt attcatgggt aatctctttt tttgtatctg tataaaacaa ggattgcacg
    23041 ggtaccttta attctgtcaa ccgattttct aatgcttgac cttgctcctg gaatgagtat
    23101 gcatttccgt cagttatata cgttggcgga aattccttag aaacatggtc agccacacta
    23161 gcttctttca attgctcact cgttttccaa tcttttgttc caatcaacga ccacgcaacg
    23221 gttttgacga aaaacttcat aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa
    23281 tcaacaggtc cccaataaga aatggttcct ttcagactat cttttggaag tagctgtttg
    23341 attttcattt gtttagcata cgcatcattc gtttgtatag ctgcatattg caatgcgatt
    23401 tgtgaacctg cactatctcc accaaaaaat aattgttcca tgtctagcaa tttgtcgtct
    23461 ttttcttcag ctaataaatc tttgatcagt tcattcactt gaagaacttg attagggtat
    23521 tctgaatcag gcgctaattc ataattcatc gcaaccactg cgatgttggc gtctgaaact
    23581 aattttgtcg caaattcttt gacacccgat ttatctccgc cgacgaatcc tccaccatgt
    23641 acccaaaata gaacaggaac aggccccttg ctgttttttg gatagtagat gtcataagta
    23701 ttctctttat acttggactc atacgtcaaa tctgtttttt tcgccacgtt tttttctgct
    23761 tgatcgaacg tttttttatc agtgatttga acagtatttg aaaacatatg gttgatcaag
    23821 aatgctccag gtctggggga aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga
    23881 atgattccga agaaccatcc gataaattta agaattttct ttttcataag gctccctcag
    23941 tagttagtat taagcattct gattatacca tagtgttatt tcctatcaag ctctcctaga
    24001 tgatttaatg attttcccca aacttcttct gcaatgcttt tgacaaaaga aattttttcc
    24061 attgttcttc aaacaaaaca ttttcttctt ctgttgaagc aaatccacat tgaggactta
    24121 agcacaaacg atccaaaggc agatatcgtg tcgcttcgta gatccggtca atcacttgct
    24181 ggtgctcttc catttcgcca tttttcgtta cagtcaaaat ctaagacaac taatttatct
    24241 tcagagactt tctctaaaag aacaaaactc ccagcacgtt cactatcgta ttctaaataa
    24301 taggcacgga cattttcttg agtaaaataa tgggtctgct acgtcgtcat cccccctgat
    24361 gccgccaaaa tcgaataata atttccgcgt caaacatgta tatttagtgt tgaatcattt
    24421 gagaatatga aaataaaaat ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa
    24481 atctgagaca gaatgacgtt cattctgacc cagatttgat tttgcacaac tcaacagtcc
    24541 ttattggcaa atcgccaaaa taatgtagac taactaaaa
//
LOCUS       DAFELK010000046        24178 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFELK010000046
VERSION     DAFELK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.047"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..449)
                     /locus_tag="LP433_002047"
     CDS             complement(<1..449)
                     /locus_tag="LP433_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2006187.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYLK"
     gene            793..1200
                     /locus_tag="LP433_002048"
     CDS             793..1200
                     /locus_tag="LP433_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006188.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            1214..1615
                     /locus_tag="LP433_002049"
     CDS             1214..1615
                     /locus_tag="LP433_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006189.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1617..1988
                     /locus_tag="LP433_002050"
     CDS             1617..1988
                     /locus_tag="LP433_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006190.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(2024..2326)
                     /locus_tag="LP433_002051"
     CDS             complement(2024..2326)
                     /locus_tag="LP433_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006191.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2575..2775)
                     /locus_tag="LP433_002052"
     CDS             complement(2575..2775)
                     /locus_tag="LP433_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2006192.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(3080..4312)
                     /locus_tag="LP433_002053"
     CDS             complement(3080..4312)
                     /locus_tag="LP433_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBL2006193.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4566..5135
                     /locus_tag="LP433_002054"
     CDS             4566..5135
                     /locus_tag="LP433_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2006194.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(5313..5753)
                     /locus_tag="LP433_002055"
     CDS             complement(5313..5753)
                     /locus_tag="LP433_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBL2006195.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5911..6675
                     /gene="map"
                     /locus_tag="LP433_002056"
     CDS             5911..6675
                     /gene="map"
                     /locus_tag="LP433_002056"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBL2006196.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6707..7630
                     /locus_tag="LP433_002057"
     CDS             6707..7630
                     /locus_tag="LP433_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBL2006197.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7706..8845
                     /locus_tag="LP433_002058"
     CDS             7706..8845
                     /locus_tag="LP433_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBL2006198.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8838..9638
                     /locus_tag="LP433_002059"
     CDS             8838..9638
                     /locus_tag="LP433_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2006199.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9638..10465
                     /locus_tag="LP433_002060"
     CDS             9638..10465
                     /locus_tag="LP433_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2006200.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            10443..11177
                     /locus_tag="LP433_002061"
     CDS             10443..11177
                     /locus_tag="LP433_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2006201.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            11277..12143
                     /gene="rfbA"
                     /locus_tag="LP433_002062"
     CDS             11277..12143
                     /gene="rfbA"
                     /locus_tag="LP433_002062"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBL2006202.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            12157..12729
                     /gene="rfbC"
                     /locus_tag="LP433_002063"
     CDS             12157..12729
                     /gene="rfbC"
                     /locus_tag="LP433_002063"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBL2006203.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12751..13779
                     /gene="rfbB"
                     /locus_tag="LP433_002064"
     CDS             12751..13779
                     /gene="rfbB"
                     /locus_tag="LP433_002064"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBL2006204.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13877..14728
                     /gene="rfbD"
                     /locus_tag="LP433_002065"
     CDS             13877..14728
                     /gene="rfbD"
                     /locus_tag="LP433_002065"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBL2006205.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14763..16796
                     /locus_tag="LP433_002066"
     CDS             14763..16796
                     /locus_tag="LP433_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006206.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16840..18120
                     /locus_tag="LP433_002067"
     CDS             16840..18120
                     /locus_tag="LP433_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBL2006207.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            18330..19136
                     /locus_tag="LP433_002068"
     CDS             18330..19136
                     /locus_tag="LP433_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2006208.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            19148..20368
                     /locus_tag="LP433_002069"
     CDS             19148..20368
                     /locus_tag="LP433_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006209.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEIFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            20358..21944
                     /locus_tag="LP433_002070"
     CDS             20358..21944
                     /locus_tag="LP433_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2006210.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21983..24121
                     /locus_tag="LP433_002071"
     CDS             21983..24121
                     /locus_tag="LP433_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2006211.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7708 a         4037 c         4919 g         7514 t
ORIGIN      
        1 ttttttaaat atgcgttctc tgctcttaaa cgaataactt cttcttcaag agactcatct
       61 ttaagttttt taggaatgtt tagcttggaa ttcatactaa tttttctgcc ccttttttgg
      121 ctctcaagtg aagaagcacc gccttcttca tattgctcta tccatttact tagagttcta
      181 tttgaaccga tattaaattt tttagcagtt tcttggatag aaagaccatt tgtttccata
      241 tattctataa catcaagttt aaattttgta gtgtagcttt tgccacctcc aaccaagcct
      301 tcccaaccat gatagttata aatccttacc caatgtctaa ccagtgtacg atttatttga
      361 tatttatgtg caagatattt gtagccgcct tcgttattta aatagtctga aactactttt
      421 ttcttaaaaa caaatgtata tttccgcaaa aaaagcaccc cttttaatta gatttctagt
      481 ctaacttttg gggtgcacat catttttgag gggaagtaca tatagttgtt gatatagttg
      541 ctaatattgt tagctaattt gttagtaaaa ctgtatacga atttagatag taaaaaaaca
      601 gtttgttcct tatatagagg cacttttact actgattaaa tgtcagatat gcttacaaat
      661 atacttataa atatgcttac aaaattagct aatatttccg ttgacaaagc tttgttacta
      721 ttgttaaact aaattgacta gcaaaagtga aacataaatt tattaaataa atgtaaaaat
      781 taggagaaat caatgtctta tagagtacaa ttaataattt cagaagatgt agaaagtcag
      841 caatttggca ctaatgttat taataaagta attaatccag ctctttctat taatgcgcct
      901 ttaattccta ctgctttatc attttctgta acagctgtgg tgtctgagat agaggataca
      961 gaaaagataa aaatagtaga aattgaagtt ttaaacaaga atgaaaaaca aattttttct
     1021 acgggtgaag tatcggtaag cttgcctcct caagttaacg atataaactt taatataaac
     1081 gccagaaatg tcttggttga agaagcagga gagcattatg ctgttgttaa atttaatgga
     1141 actgagattg gaaggcaaat ctttgatatc aaggtcaaca aaccagtgga aaaaaattaa
     1201 ggagacgata cggatgcttg atatagtacc atcaaataca catcggagtg gtagcttaat
     1261 aaattttgct gcgatttttg cttgcgcatc ggtaattcta gcatctccag ttgttgtgga
     1321 tgcaagttct actccgaaaa ctaaaaatga taatcaactt gtaattacta caaaaaatga
     1381 gattaacaca atttcaagta atgatggcaa aatttttgat gtgataaata cggttttaaa
     1441 aagaaaagct gaaatcaata taaaatatga tgaagattta aacttgtatt tctttgttat
     1501 caaaacaaca tctgaattgt tttcctcaga ttacgatgtt ttggatactc tcgataatgt
     1561 attatctgac tataaatata tggggaaatc tgtagtagca actttggggg aataaaatgt
     1621 ttgactttaa tgaatattta tctatttcca aacaaattga atcagatgat aaatataatt
     1681 ctaaagaatc ttatagaaga actgctgttt caagagcata ctacagtgct tttaaaaaat
     1741 ctgatgagta tttgaaagaa aattatgata ttatttataa tggaagtagc ggaaaaggaa
     1801 gccaccaaac cgtttggaat ttgttttcaa cagttaagga attgaatacc ttaggaatac
     1861 ataatagtgg gtatagaatg ttagagaaaa gaaaatgtgc tgactatatt cctaatgaaa
     1921 ccattacgaa aacagatatg gcgctgatga atcgagaagc agaaaaaata ataaacaaac
     1981 tcacctaatg aatttcaagc gagtttgttt gttatttttt tatttaatct ttgtatcttt
     2041 ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgcta cgtgcgtccg
     2101 gcacgtcagt cacgatatca aacaaaaagt atacaccctt cttcattcta gttttcgcag
     2161 caggaatttt gaaatagttc ttattagaat agtagagatt gattaataag ctatcttcga
     2221 ttgctaaaaa gaaaacttct gaattccata ctttataaaa atctttgata aatctattcg
     2281 aagggtcaaa tttaaaccat aattgtgttt ttccttccat cagcataaaa gttcacctca
     2341 aaaagagtat acgaacgaat gttctttttg tgaaggcgga atttaatata ctgaataata
     2401 gaaaacaagt acttgtgcca aattatgtgc caaaaaaatt cgaattcaac aaaatgtaaa
     2461 caaatagaaa accttctata ttaagatttc ctgcaataac aaacacaaca gaagacgtgt
     2521 aatagttagt caggaacgta caaataaccc ctgtatcctt tgcggtacag ggggttattt
     2581 tgtataagta gacattgtag tttctaaact gctatgtcct aaacgtttcg atacgctaag
     2641 tatatttact ccttgataaa gtaaaataga tgcatgcgta tgtcttagtc catcaataaa
     2701 cagtcgaaga gaaaataggg aaaaattgat tactaaagaa aaacttacta ggtcgacggt
     2761 gtagttgatt ttcatacttc aatagattcg aattaaacga tttcgattgg cttataccag
     2821 tcctatccaa cgaaagatat atcgttctta actctagcgg tataacttga agctttacgt
     2881 aaagccaatg ggaatgaact ggagatgact ttttattatt tttagtaata gctgatgggt
     2941 taatacttac aactttcctt ttcaaagtac catataaaaa aacggtgggg ttgtttagcg
     3001 aaataaagga tctaagccaa tagcttagat cctttattct atgctttata ttattttttg
     3061 catgtgtgcg aaagtatact caagcccaat cgccatttcg gaaaatcggt actgtagagc
     3121 catcttcacg gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg
     3181 tttgacttct attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt
     3241 tcacactgaa ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata
     3301 atgtattgaa aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga
     3361 cttctcctaa acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc
     3421 cttgttcggc agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga
     3481 tgatggtgcc agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac
     3541 tgtcaggtgc tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag
     3601 cattatagct tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg
     3661 taccgggagc agtatagtga agggcagaaa attgttctcg attcaattct tctgcttttt
     3721 ttgctaattt ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag
     3781 tcgttttgaa aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga
     3841 agacttttgc tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg
     3901 cttgagttgc cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta
     3961 ctcgatggct atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc
     4021 ttgctccttt ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa
     4081 tacgatccgt tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa
     4141 cgataacctc agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg
     4201 cctgttccac gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt
     4261 ctgcaattaa gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa
     4321 ttcctcctca ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa
     4381 caatgaggct ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat
     4441 gttactactt gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa
     4501 aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta aggagattaa
     4561 aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct gcttatgaag
     4621 tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac aaaatgaatt
     4681 gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga caagctcttt
     4741 ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat acagggaata
     4801 cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag aagttgtatc
     4861 gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc tcttatactt
     4921 actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa gagcagatcg
     4981 aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg atgtcttcaa
     5041 gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt atagatgcta
     5101 tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt ccacaaatca
     5161 gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca gcgtatgcat
     5221 ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat acagattgaa
     5281 taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag ttctttagcg
     5341 aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt aacattttcg
     5401 gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac cgatttgcag
     5461 aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc caatagatcc
     5521 aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc atcatcgtat
     5581 gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc tacttgggta
     5641 cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac aatatcggcg
     5701 atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc catgatgtgc
     5761 ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt gaaaagaaaa
     5821 taaaacctaa agacacctgg ggaatgtcat ttggctaaat gtatgccgct atgttaaaat
     5881 gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc acgtgaaatt
     5941 gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct gcgtgatttt
     6001 ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta tatcgagagt
     6061 catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac ttgtatcagt
     6121 ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa cggtgatttg
     6181 gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg ttgggcctat
     6241 gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa gaaagctttg
     6301 tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg tcatgctatc
     6361 caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg tcatggcgtt
     6421 ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg aaaagggttg
     6481 cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg aacttggaaa
     6541 atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact ttcttgccaa
     6601 tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc acaaggagaa
     6661 gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga aagtttggaa
     6721 caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa agcgcatcac
     6781 tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct tgtctttatt
     6841 tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc aagagactgt
     6901 actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg gtcctgcaat
     6961 caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat tagcggcttt
     7021 atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag cgtatggcgt
     7081 agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca ttgtcttgtt
     7141 catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga ttttggatgc
     7201 tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa ctttgaagtg
     7261 gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa ttgtccctaa
     7321 tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg tcggctggat
     7381 gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga tcagcggtta
     7441 tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg ctacgatcat
     7501 cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc atcaaatcaa
     7561 aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat tttctcataa
     7621 aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat aataattatg
     7681 actcttaatt aaagtaggtg cccatatgct tgtttctttt agtatggtta taagattttt
     7741 tctgacaatt ttattatcac tgatattaac acctgtattc aaaatcattt cagtacaaac
     7801 aggtatggtc gacaaaccaa atgaaagaag aataaataaa gttccaatgc cttcagcggg
     7861 cggactgcct atctttattt catttgttat atcgacttta ttcttattcc gtaaaattat
     7921 ccctcaatcg tatattgtac cgatcttgat tgcttcttta gtaatcatag tcacaggagt
     7981 gctcgatgat aaatatgagc tgacacctaa acaaaaaagt atagggatct tgattgcttc
     8041 tcttattatt tattttgtag cagatatacg tattgattcc ttcacgcttc cttttattgg
     8101 atatatccaa ctaggctggc ttagttttcc cgtaacgatt ttttggatct tcggtatcac
     8161 gaatgcggtc aatctgattg acggtttgga tgggctggcg gcagggattt cattgatcgg
     8221 tttaattacg ataggaatca ttggatattt tttcctccat gcttctacag tgtatattcc
     8281 agttgttatt ttctgtcttg tagcaagtat tatcggtttt tttccttaca atttttatcc
     8341 ggcaaagatt tatttaggcg atacaggagc tctattccta gggtttatga tggccgtcct
     8401 ttcactacaa gggctgaaga acgtgacttt tgtttcatcg atttctttgc tgatcgtcat
     8461 gggagtgccg gtaacagaca cgttttttgc tatcattagg agaaaagcaa accgtgtttc
     8521 tttttctaca gcagataaaa aacatcttca tcaccgacta atcagtttag gctttactca
     8581 taaaggtgct gtcctgacga tttatgcgat ggctttgatg ttttctttca cagctatggt
     8641 catgaattat actggaagaa tcggaacgat catattgatt attgccatgt tgtttgctgc
     8701 aattttatta tttgaattga ttggtctgat caatgagaaa catcagttta ttttaaaaac
     8761 attgcgattt ttagggaata aagagtaccg tacgcaagta aaacagaaat atttgaagaa
     8821 atggaaccgt catatagatg aataacaaat taaaccagcc gatccttatt agtattgtga
     8881 cggcaaacag tgataaaatt tttcggacac tagataattt tatttcaact gtaaaagatg
     8941 aaacagcagt aaaaatccga atttttgaca acaattcact tcccgagtac aaaaaaagac
     9001 taacagagta taggaaatat ccctacatcg atatctattt tcatgatgaa aattccggat
     9061 ttggttatgg acataatcac aatctgatag ctagcgattc tcgctatggc attatttgta
     9121 acccagatat tttagtggat gaagagacag ttacagcatt ggtcttgtta ttgaaagaac
     9181 atccggaatg tgcgatgtta gcacctaaga ttcttaatga agatggaaca actcagcacc
     9241 tcatccgtga gcagctggct gtttttgatt acgttttgcg ctttgtgcct ttcaaatggg
     9301 tcaaaaaaaa gtttgacaaa cgactggctg tgtttgaatg ccgaggattg cctactgatg
     9361 ctaatagtta tgtacggatg atctcaggta gttttatggt agctgatatt gataaattta
     9421 aagagataaa ggggtttgat gagcgtttct tcatgtactt tgaagacaac gacttgtgtt
     9481 tgagttttga aaaagcaggt tacaagttat tgtacacacc cttttatgca gttatccatt
     9541 tttacgggaa gggtgcgcat cgaaatgcaa aactgtttcg cgtgtttttg acttctatga
     9601 tgaaattttt caataagtgg gggtggcgtt ttttctgatg aaaccagaaa tattagtagt
     9661 cgttgtgctt tatcagcaac tattcagtca atctccagct tatggaccat taagcaaagc
     9721 acttagcgaa aagcaaattc agcttattat ttacgataat agtcctcaaa ggcagcaaaa
     9781 tgagctgttt gaaaaagaaa atatcgttta tcatcatgat ccgcaaaatc ctggtttagc
     9841 ggtggcttat aattttgcgt tgtctcaagc agatgaagga acacgttgtc tcgtcactct
     9901 ggatcaggat acgaggctag tcgacgatta ttttgaacta ttgcgtaaag taacctttac
     9961 agatgaatgt gttgctgcag ttccgatgat tttttctggg agccgacaag tttctcccct
    10021 atattcagat cgttatatca atcgtacagc tcaagcagta gaagttgaag gcccaacagc
    10081 tgaacgaatc atggcaatca attcaggtgt tgcctggtct gtcaaatttc taaaaaagat
    10141 tggcgggttt aatcctgctt tttctttaga ttttttggat cattggctgt tttggaaagt
    10201 ggatcagttg gaaaaaactg tggagatcct tcctgtacga atggaacatg atctttcggt
    10261 tttagactat gaaaaagttt caagtaatcg ataccgttct attttacaag cagaaaatcg
    10321 attttatcat gaatatgatc aaaggcattt atccagtcac cgacgacaat tattgttaag
    10381 aacagctaaa cagttcttga ccgtcaaaaa ccggcatatc tggcggatga ctttgcgctc
    10441 atatgttaag aattggaagg tgtgaattcg tgcgttcggt ttgtatagct acctttaatg
    10501 gaggcagata tttaagagag cagttagata gtattttatc tcagctttca gcagaagatg
    10561 aagtagtcat ttctgatgat gggtcagtag atgatacatg ggatatatta actgaatacg
    10621 cagaaaaaga taagcgaatc cagctttttt cggggcctcg tcaaggattg atcgctaatt
    10681 ttggttatgc gatccagcag acgaaaggag atctaatctt tttggcagac caagatgatg
    10741 tttggttgga gacaaaagtg aaaaagatca ctgactattt tgagcagaat ccggatcagc
    10801 tagtagtagt ttctgattta atcattgtgg acagcgagct gcaagagatc catgattcgt
    10861 atttttcgtt tcgaaattcc aaagaaggat ggcttaataa tgtgataaga agtcactata
    10921 ttggtgctgg tatggctttc cggtcttctt taaaacccga tattttgccg atcccgtcag
    10981 aagtgccgat gcatgatatg tggattggtt tgctgggagg aaagaagact gggttcctaa
    11041 gagaaccgtt aactctgtac cgaagacatg atttaaacgc gagtgagatt gaaacacatt
    11101 ctaaattacg gcaaaaaatt tcttggcgtg ttcatctgat tacggcgttg atcaaacgaa
    11161 aatggtttaa acgttgataa aagatgttta aatccttaat atttccatga caaatataac
    11221 aattgatgag ataataacaa agtgaaattt gaaatcaaaa aggagagcag atatccatga
    11281 agggaatcat tcttgctggg ggcagcggaa cacgtctgta ccctttaaca aaggcaacat
    11341 cgaaacaatt gatgccgatt tatgacaaac caatgattta ttatccaatg tctactctga
    11401 tgttggcggg aatcaaagaa attctgatta tttcaacgcc acaagataca ccacgtttca
    11461 aggaattatt tggaaacgga aatgatttag gactgcagat cgaatatgca gtacaagaaa
    11521 gtccagatgg attggcacaa gcgtttatca ttggagaaga atttattgga gatgatagtg
    11581 tctgcttggt attaggggac aatatttact atggtggcgg tctgtctaaa atgttgcaac
    11641 gagcagcttc aaaagataca ggcgcgacag tatttggcta tcatgtcaat gatccagaac
    11701 gctttggtgt agtagaattt gatgagaata tgcaagcttt gtcgattgaa gaaaagcctg
    11761 ctcagccaaa atcaaattac gctgtaactg gcctttattt ttatgacaat gaggtaattt
    11821 ctatcgctaa aggtatcaaa ccttcagaac gtggagaact agagattacg gatgtcaata
    11881 aagcatattt ggataaagga aaactatccg tagaacttat gggacgcgga tttgcttggc
    11941 ttgatacagg aacacatgaa tcattgcttg aagcatctac ctttatcgaa acaattgaaa
    12001 aacgtcagaa cttaaaagtg gcttgtttgg aagaaattgc ttaccgtatg ggctacatcg
    12061 ataaggaaca attgctggcc cttgcacagc cattgaaaaa aaatcaatac ggtcaatatt
    12121 tattgaattt ggccgctgaa taaggagtcc ttacagatga aagtaacaga tacaaaatta
    12181 acagatgtca aaatcgtaga aatggacgtc tttggcgatc atcgcggttt cttcacagaa
    12241 agttattcaa aagcaaaatt tgcagaacat ggattgaaat atgactttgt tcaagacaac
    12301 cattcactat cagctgaagc tggtgtcctt cgggggcttc atttccaaaa aggagaagct
    12361 gcacagacaa aattgattcg ggtagtcact ggagcagttt tagatgtagt agtggatatc
    12421 cgcaaaggta gcccgactta tggtcaatgg gacggattta tcttatctga acataatcat
    12481 cgacagttgc ttgtacctaa aggatatgcc catggattcg ttactttgac accaaatgtg
    12541 aacttccttt ataagtgtga taattactat aatgcagaag cagatggggg catcgcattt
    12601 gatgatccag atttagcgat tgattggcca attgatccat caagagcgat tatgtcggaa
    12661 aaagatcacc gtcatccgac attaaaagaa tttgaagcag aaaatccatt tgtttacgga
    12721 gaaatctaag aattaaggag aaattttctt atgaaaaaca tcattgttac cggaggtgcc
    12781 ggattcatcg gctctaattt cgttcattac gtggtaaaca atcatccaga agtgcatgtc
    12841 actgttttgg ataaactgac ttatgcagga aacaaagaga acttggccgg acttcctagc
    12901 gatcgcgtag aattggtcgt aggagatgtt gcagatgcag aattagtgga ccgtctagta
    12961 aaagaagcgg acgcagttgt tcattacgcg gcagaatccc ataacgataa ttcattaaaa
    13021 gatcctttcc catttgtaca aacgaatatc attggtacgt atacactttt agaagcttgc
    13081 cgcaagtatg atgtacgcta tcatcacgta tctactgacg aggtttacgg cgatcttcca
    13141 ttacgtgaag acctgccagg acatggggaa ggcgaaggag aaaaattcac tgcggaaaca
    13201 ccatataatc cttcaagtcc atattcttct acaaaagctg gttcagatct gttagtaaaa
    13261 gcatgggtgc gttcttttgg cttacgtgca accatttcaa actgttcaaa caactatggt
    13321 ccttatcagc atattgaaaa atttattcct cgccaagtaa cgagtatctt aagcggtatt
    13381 cgtccaaaat tatatggcga aggaaagaat gttcgtgact ggatccatac gaatgatcat
    13441 tcttcagcag tgtggctgat tttgacgaaa ggcagaattg gcgaaaccta tctgatcggt
    13501 gcagacggtg aagaagataa taagaccgtg atggaattga tcttagaaat gatgggccaa
    13561 ccaaaagacg catacgacca tgtaaacgac cgcgcagggc acgatttgcg ttatgcaatc
    13621 gattcgacaa aattgcgaga agagctaggt tggcagcctg agtttacgaa cttccgtgat
    13681 gggttggctg acacgatcaa atggtacgaa gaacatgaag actggtggaa aaaagaaaaa
    13741 gaggccgttg aagcagcata tgccaaaaat ggacaataat acagaggaaa tttcactgta
    13801 ttaatggaaa aacacatgtg aggcaggcgc tcgcctgtct cttttttaaa ataaaaatca
    13861 aggagcggat aaccatatgt ttttattaac tggaggaaat ggacaattag gtacagaatt
    13921 gcgccattta ttagatgaaa aaaatctgcc atatgtttca acagatgcaa aagacttgga
    13981 tatcacagat gctgagaaaa caatggctta tattacagaa ttaaaacccg atgttatttt
    14041 ccattgcgca gcttacacag cagtagataa agcagaagaa gaagcaaaag aattagatga
    14101 gaaaatcaat gtcgatggca caagaaatgt agcacttgca gcaaaagctg tgaatgcaca
    14161 attcgtctat atcagtacag actatgtttt cgatggaaaa aacaaaaatg tagaatacga
    14221 agtagacgac caaacgaatc cactaaatga atatggtcgt acgaaattat taggcgaaaa
    14281 agcagtagaa gagattttag aagactatta tatcatacga acttcttggg ttttcgggat
    14341 ctatggacac aatttcgtct tcacgatgca acgcctagcg gaaacccgcg acaaactgac
    14401 tgtagtaaat gaccagtttg ggcgaccaac ttggacacgt actttggcag aatttatggt
    14461 atatgtcatc gaagaaaaag caccatttgg tatttatcat ttgtcgaacg aaaatagctg
    14521 ttcttggtat gagttcgcaa aagaaatatt gaaagataca gatgtagaag ttgcacctgt
    14581 tacgtcagaa gaatttccgc aaaaagcaac acgtccgcag tattcagtca tgagcctgaa
    14641 aaagacagaa gcgttaggtt ttgtcatacc aacttggcaa gaagcacttg cgcaaatgct
    14701 ggaagctgcc aaaaaaatga ataagtaatt tcctttttat caaatagaat ttggagcatg
    14761 atatggaaaa acaaacaaga agtgcacgac gaaaagaaaa gccaaaagcg aatcaggcag
    14821 attcgaattt ggtgcttgac ctgtttctaa aactccgcta tcttattggc gttttagtca
    14881 tcgtggtcat cgttactttt aatttaaacg gaagttcact tggtgtttgg gataaatatg
    14941 tgtcgcaaag agacgatggg aaaaaaactg atgtgatttt tggacagaat cgggaagtgc
    15001 ggtcagacga atggctggtg cagacacctt tttacctctc acaagctgaa gaggactttt
    15061 cgttggtgaa cgaggattat tcattaaacg gacaaaacat gatcattgcg tataattctc
    15121 ctgtaaagga tattacggtt atcggaaaac cattcaactg gggattcttt ttcctcggaa
    15181 gagatcgagg actttccttt tattgggcga tgaaattagt cgtcatggtc ttgcttggat
    15241 tcgaagtact gatgatatta acgaagagga aaaaagctct atcgctaatc ggtgcatttg
    15301 cgctgacatt ttctccagca gtccagtggt ggttcatgca acatgtgggc gatttgattt
    15361 tctttacttt gggactgatg attgcttttt atcattattt ctacaatcat gataaaaaat
    15421 ggctacgaac gttgatgatg cttttggtgg ttattttcgg tattgggttt attttagtga
    15481 tttacccagc ccatcaagtg atgctggcgt acttgctgat tttttatttt gttggcctgc
    15541 ttatttacta tagcaagaaa gtttcatggg atctgttgga tgtagtgttg attggagggg
    15601 cagttttatt tattggcgga gtcatggttc atttctggct aacgtcaaaa gacgcattgt
    15661 tagcttcttt gaatacctta tatccaggaa aacgggtaag tactggagga aagtggacga
    15721 ttggcgaatt tttttctttc cttacaaatt ggaaaattcc ttttgaagat atcaactatt
    15781 cgaataactc tgaagtggcc ctgttctatc acttttttcc aactgtattc ctagcaagtc
    15841 catttgtgtt atttggcaaa aaagatagcg aacaaaagtt actgggacgt attttgatga
    15901 ttttttgtct gttttctatc ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa
    15961 tcactctgct gtcttatgtt cctccattaa gagccatcct tacttttagt tttgcggctt
    16021 gtttattatc gatctggttt atcgcttata tttggagaga agatgttatt cctatttggt
    16081 ataaattcat tttgttggca gtaaatgcat ggtcttattt ctatgcgatt acgcattcga
    16141 aaatggataa ttatttttcg gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga
    16201 ttttagcttt tgcattattt ggctggagac gcttgtttta cctcgctttt gtcgccttag
    16261 ttatcgtatc tggctttttc gtcaatccag tcgtagaagg tacaggagcg atttttgaaa
    16321 aaacactggc aaaagaaatc caaaaaatcg atcaacaaga tcctggtaaa gtttggttgt
    16381 ctgaagatga attatataac ttcaccccaa cattgggagt gaaatccttc aatacagtac
    16441 gcttttatcc agatatagct gcatggaaga aaatcgatcc gaaagaagaa tacgagaagt
    16501 attataatcg gtatgctcat acaagagctt ttatcgctaa ggaagataca aagttcattt
    16561 tagatcgtcc agatatgttt tcggtcacgt tgaattttga agacgcagaa aaattaggga
    16621 tcgactatgt gatcagtaaa cgaccattaa ctgattacaa ccaattatat gaagcgcagt
    16681 tcacgcagct atatggaccg gataaagacg gttatatgat ttttaaagta gaatatccgg
    16741 attatccaga tgtaccacaa acacaaactc aggaaaatca gctagtcgta cagtaatagg
    16801 ctagctgaga ataatcctga aatattagta gaaaggagag tgaagataat tcaagcaatc
    16861 gtacaaaaat ttgtcaacaa aatgagtgtc ggtttcttgc ttttgttgct gacgctagtc
    16921 ttttttgttt ggacagcagg ggtaggtttt ccagcaactt tgtttatata taacaatagt
    16981 tcattactta tcgcttttag tgtggctatt ttgctcattt taaatgttta taaagcaaaa
    17041 ggcgtcgatt ttctttatct aggtgttgcg cttgcccttt tcattttctt ttcttacttt
    17101 cgggaattaa gaaatgagtc tttatttgga gacttactgt ttcctttgat tattttattt
    17161 tgtttagtaa ttaaatggat cgagtggaca aaatgggatc gcggtattta tctgattgtc
    17221 tttacggtct tcctcggaat cacgttatat cgtgtattta cagagatcca agtaccagaa
    17281 ggacaaagca tctgggctcc aggcaattcg ctttctgata tttggatcaa tacgaataca
    17341 atcggaagtt ctttgatgac tcttgcttta ttgatcagtg gatttgccag ttcttttgaa
    17401 cgatggtatg ttcgaatcat cggtgggata gcagtcgttg cagccttttt aggtatttgg
    17461 gtctgccaat ctagaggtgc attagtcgcg ttgattgttt ttgcgatatt ggatctttta
    17521 cctaaatcgt tgatgcgtgt cattcgtgcg ccatttattg cctacacggt tacgattctt
    17581 ttagctttgc cgatttctta tctggcggct gtctctgaaa aagtcaattt gtttaccggt
    17641 cgagaagata tttggcataa attctatcag acgctaggag aaaaatctga acaagtttta
    17701 ctaggaatga aaacatttat cttccagcga ggaaaccaat ttttaggaaa ccacaatagt
    17761 tataattcta ttttgaatat ctatggattg ataggatttg ggattgctgc tttgctgctt
    17821 atccttttta ttggtcgctt aacgttgaaa gcagatttat ccaacgggca gatgactttt
    17881 atctgggcct tttttgcggt gatgatgcag tcatttatgg aggatacatt gacttcatac
    17941 cgatgggttc cgattattta tatcctgttg gctatggccg ttcatcgata tgatgaacca
    18001 gaagttacgg aggaattcta tgttatggaa gaggcatatg acgatatgac ttatgatgat
    18061 acatcttatg aggaacaacc agatagcgct cattcttcca ggatccaacg ctatcattga
    18121 taggcacaaa atacgagaga ggctgtgaca accgtcgcag ccttttttgg tttattgcaa
    18181 ttgtctagca tcttctgtaa aatagaaacg ttagagaaaa tcttgtatca tagaaaatta
    18241 agaaagaaat aagaacgcag ctcggtacca aaaatatggt aaaatggcac ttgactgtaa
    18301 ttcactgaaa atcgcttgga ggaacacaaa tgtttaaaga tttgtattta tttatgaagg
    18361 acatttatca gaacagaaaa ttactgctac agttttcgat caatgacttc aaatcaagat
    18421 atgcaggatc gtttttagga atcttatggg cgtttatcaa tccgctattt actgtattga
    18481 tttattggct ggtatttggt gttggactga aagcacaaat gatcgatgca aaatacccat
    18541 ttatcgtata tttagttacc gggatgattc cctggttctt cttctcagat gcatttgcat
    18601 caactacggt tgtttttcgg gaatatactt atttagtaaa gaaagtcgta ttcaatattc
    18661 gtatcttgcc cacgacgaaa atcctatcca atctgtacac ccatttattc ttcattctga
    18721 ttggcatagc tgtcgcgctt ataaatggta tatatccttc agcaatgtct ttacagctga
    18781 tttattattt attttgcatg tgtgctttct tgacaggatt gacttggctg acggcatcga
    18841 tccaaccatt tttacctgat atcatgcaat taattacgat cgtgctgcag ttgatcatgt
    18901 ggacattacc gatattatgg agccctaatc agtttgattc aggtcttgta agcatattga
    18961 aattaaatcc gctgtactat gttgttcaag gttatcgtga gtcattttta agtgaagctt
    19021 ggttctggga gcatggaaca tatactttgt atttctgggt tttcacgtta gtaatgttcg
    19081 taatcggctc tgcagtgttc cgtagattga aaccacattt ttcagatgtg ctgtaaggag
    19141 aatagctatg acagaatatg caattagact aaaagatatc acaaaatctt ataatatgta
    19201 cgcaaaacct tcggatcgat ttcgtgaagc cctcaatcct tttaagaaat cctatcatga
    19261 tgtattttat gcgttgaaaa acgtgaatgt agaaataaaa aaaggtgaga tgatcggttt
    19321 cgtgggagaa aacggatcgg gaaaatctac aatgttgaaa atcattacgg gagtactgac
    19381 accaacatcc ggcacgatgg aaatcgaagg aaaaatctca gctttgctag aactaggatc
    19441 aggattcaat cctgagtatt ctggctatga aaatatctat ttaaatggaa tggttctagg
    19501 attttcaaga gaagaagtcg atgaaatggt cgatgatatc attgaatttg ctgacatcgg
    19561 cgaccatatt tatcaacctg taaaaaccta ttcaagtggg atgttcgttc gtctagcttt
    19621 tgctgtagcg atcaatgtga atcctgatat tttgattgtg gatgaagcat tggcagtagg
    19681 agatcttgaa tttcaactaa aatgtatgga aatatttaca gaaatcaaga actcgggaaa
    19741 gacgatttta ttcgtttctc atgatattag ttcgattcgc cgtttttgtg atcgttccta
    19801 ttggttgaaa aatggaaaag ttgtcgaata tggtgatacg atggaagtaa cgacgaatta
    19861 cgaaaacttt ttgaagaaaa aatcagttaa aacagtagat cgaaataaaa accaagtaga
    19921 acgcttcgca gctccagata tcgtagacgt gacgaaagcc gaattgttgg ataaagataa
    19981 aaatccagtg gatatgctgg aacaaggaga aaaactatac gttaaagtaa cctatgaagt
    20041 aaaagacgat acaatcaaaa atccagtttt aggaattgct ctgcgtacag tcgacaattt
    20101 ttatgtgtgc ggactcaata ctctactaga tggtatcaag atcccttgga aaaaaggtga
    20161 gaatatcttt tatctggagt atgaaaagtt aggtttgtta gctggtgaat attattttga
    20221 cgttgcggtc tttgaagaaa atgcaacggt tcctttggta tacaagacaa aatacatgaa
    20281 cttgtttgtc agcggttctt atatcggaga aggcatcgtg gtcttagacc ataaatggga
    20341 agaagggact catagcaatg aaatatgatt ttgaaatgga cctagatgaa caaagcagtg
    20401 tgggaaaaat tgccgcacag atcaaaccag gaagtaaagt tttagagttt ggtcctggaa
    20461 acggccgatt aacgaaacat ttgatcggag caaaacaatg tgaagtgagc attgtcgagc
    20521 tagataagga attgttcgat tttgtcagcg agtttgccca agatggattt tatggagata
    20581 tcgaaagttt tgaatgggca aactattatg ctggacaaac atttgattac gttttgtttg
    20641 ccgatgtttt agaacatttg gtagatcctg gaaaaacgtt gaagaaagtt agagaatttt
    20701 tgaatgaaga aggagaaatt ctaattacat tccctaacct tgcgcataat tctgtcatga
    20761 ttgatttgtt caataatcaa ttgccatggg cttcttatgg tttgctagat gaaacccata
    20821 attcttttta tactcatgat ggcttccaaa aagtttttga aaaagcagga ttatacatca
    20881 atattgaaga ttatttgtac ttagctgtag gtgatacaga attaaaatca acttatgaag
    20941 aattgccgga agctgtacgt tatgatttca aaatgcgacc atttggcgaa gtctaccaat
    21001 acttcttctc attgatgaaa catccagtag cacaaagttc cattgcgcag ccgcaaaatt
    21061 ctaattatgt gaaagtatta gaagtaatcc agcaaacgaa acaagatgaa ataattcaac
    21121 aaataccatt caataatttc acaggggaaa atgagacact aagtttccat gtatcagaat
    21181 tagcagaacg aatggtgttt cgcttcgcgc agcaacctag ctttatcgaa ttcagcgcag
    21241 aagctgctgg agaaaaactc acatttatcg attcaaatgc tgtagtcaaa acagtaaatg
    21301 attgttattt gtttgatggt aaagatttac cagagttctt tttaacggat attgcaggga
    21361 aagaagtgac tatccattgt cactatcgtt ttatcggaga attgacacca acaatgaaag
    21421 aattgctgga aacaatccgt ccaatggctg aagttacaaa gcagctttct gagaaaaatg
    21481 atgaattaga aagagaaaat cattatctta ttgagaataa tacaagatta gatcagacgt
    21541 tgaaaacaac cataaatcgc tattgcacgt tgttggaaag tgatgaatgg acaatcaaac
    21601 atagattagg gcgacgtaag aaagaaacat cgaaaaaaat ccaagaaaaa gagctttctc
    21661 tatgtattga cgaaaaaatc tgggatgcag aaacaaagat attgaaaatc atcgggtggg
    21721 gaatcgctaa ttcggatcgc caaccattgt cctataagtt atcagccgac caatcaccat
    21781 tttttgaagc aattcctgtt ttacgagaag aagtcaatca agcaaaacag ctagctgaag
    21841 gagcaaaagc aggatttgaa ctgcggatcc tttgcgagaa ggaacgttca ttcttagttg
    21901 aagcagtggc tcaaaatggt caatcatgga tcattgaaat gtaaataatg attaacttat
    21961 aaagataagg agtaaacgaa tcgtgcaaaa aaaagaaatt gccgtattta tcgatcaaat
    22021 cactcgtgaa cgggccactg gcgatttgct tattgtgggc tgggcaattg atgaagtgac
    22081 caaagaaatc cctacgataa aggtagaaaa agaaaatgtg attgctgaag caacacatgt
    22141 cgtaagattg gatatcaatc atttatataa tcttgatgtt aagacccaaa gcggttttaa
    22201 ggtacgttta tcagggaaaa tgagaggaaa agcaatctta gacttccaaa cagcaagaca
    22261 tcaaaatggc atagctgtga aattaaacgg taaatatcct tatgatgacg gcattgaatc
    22321 ttcatgggaa agaaaaaaaa gattactgaa aaaagggata aattatgcaa ggactcatgg
    22381 cgtaaaaaaa gcaatccgcc gggtcaaact ggaattgaaa ccaggatcga tcgactatgc
    22441 agagtggatc agtcgtcatg agaaacctga tctgaaagag caaaggaaag aagtacaagg
    22501 atttgcctac cgcccattga tttccatact tatgcctgtc tataacgttg aaatcaaatg
    22561 gctcgaaaaa tgcattgatt cggtacttga tcaaacgtat gatcactggg aactatgtat
    22621 cagtgatgat gcttctactg atccagctat ccgaaagtgt ctagaatcct atcaagcaaa
    22681 agatgataga attaaagtcg ttttccgaca agaaaatgga cacatcagtc tggcaactaa
    22741 ttctgcattg gaaatggcag aaggagagtt tatagcgctc ttagataatg atgacgaatt
    22801 acctccattt gccttatatg aagtggcaaa agtgctaaac gtacatccag aactggattt
    22861 gatctacagt gacgaagata aaatcgatgc agatgggaat cgctttgacc cgcacttcaa
    22921 agcagactgg tctcccgata cattgatggg aaataattat atctctcact taggcgtata
    22981 tcggacaagc attgttaagg aacttggcgg tttccgtaaa ggatatgaag gctctcaaga
    23041 ttatgatttg gttcttcgtg tgacagaaca aattcctgca gaacacattt accacattga
    23101 ccgtgtcttg tatcattggc ggacgatccc gggatcaact gcaagcaatg gagaagctaa
    23161 aagctacatc tatgattctg gagtgaaagc attgacagat gctctatcta gaagaaatat
    23221 caagggaagc gtacatcctg gcagaatttc tggtttttat gaaatcactt atgatgtttt
    23281 gcaagaagac ttggtcagtg tgatcattcc aactaagaat ggctatgaag atctaaaaac
    23341 ttgtgtggat tcgatcatcg aaaaaacgtc ttatccaaat tatgaaatca ttattgcaga
    23401 taatggaagt acagatccta aaatgcaaga attatttgca gaatacaagc atcagctgaa
    23461 agaccgattt atcgtcgaat taattgacat tccattcaat tattcacgta tcaacaatct
    23521 ggcagcagaa aaagcaaacg gcaaatactt tttattcttg aataacgata cagaagtgat
    23581 tgaacctgac tggatgacag cgatggtttc ttatgcacag tttgatcgaa tcggctgtgt
    23641 aggagcaaaa ttattttatc cggatgatac aacgcagcat gcaggtgtat tattagggat
    23701 cggtggcgtt gcaggacatg cattgaataa ctatgatcga acacattgtg gttactttgg
    23761 ccgattggtc attgacgtca attacttagc agtcactgca gcttgtatga tggtcaaggc
    23821 agctgacttc aatgctgtca atggatttga tgaaatatta gaagtagcat tcaacgatgt
    23881 tgacttgtgc ttgaaagttt atgaactggg tcgttacaat gtctatgcac atcaagcaga
    23941 attgtaccat ttcgaatcta aatcaagagg ttatgaagat acaccagaaa aacaaagacg
    24001 ttttgctggg gaaatcaaaa aaatgcaaga taagtggcct tcttatattg ctcatgaccc
    24061 attttataac gataatctaa ctaaagaagg aatcggcgat ttttcgttga gacctgattg
    24121 attaaaagaa ctgtattttc atttttatta atgaaaatac agttctttta atttaatt
//
LOCUS       DAFELK010000047        22545 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFELK010000047
VERSION     DAFELK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.048"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(451..1761)
                     /locus_tag="LP433_002072"
     CDS             complement(451..1761)
                     /locus_tag="LP433_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL2006212.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="LP433_002073"
     CDS             complement(1773..3191)
                     /locus_tag="LP433_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2006213.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="LP433_002074"
     CDS             complement(3431..4999)
                     /locus_tag="LP433_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL2006214.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="LP433_002075"
     CDS             complement(5003..5413)
                     /locus_tag="LP433_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBL2006215.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="LP433_002076"
     CDS             complement(5410..6333)
                     /locus_tag="LP433_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBL2006216.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="LP433_002077"
     CDS             complement(6330..7208)
                     /locus_tag="LP433_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBL2006217.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="LP433_002078"
     CDS             complement(7195..8532)
                     /locus_tag="LP433_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL2006218.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="LP433_002079"
     CDS             complement(8535..9638)
                     /locus_tag="LP433_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL2006219.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="LP433_002080"
     CDS             complement(9712..11220)
                     /locus_tag="LP433_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2006220.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="LP433_002081"
     CDS             complement(11186..11878)
                     /locus_tag="LP433_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL2006221.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="LP433_002082"
     CDS             complement(11900..12874)
                     /locus_tag="LP433_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2006222.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="LP433_002083"
     CDS             13174..14046
                     /locus_tag="LP433_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2006223.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14628..16826)
                     /locus_tag="LP433_002084"
     CDS             complement(14628..16826)
                     /locus_tag="LP433_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2006224.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            17058..18050
                     /locus_tag="LP433_002085"
     CDS             17058..18050
                     /locus_tag="LP433_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2006225.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            18110..19531
                     /locus_tag="LP433_002086"
     CDS             18110..19531
                     /locus_tag="LP433_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBL2006226.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19524..21023
                     /locus_tag="LP433_002087"
     CDS             19524..21023
                     /locus_tag="LP433_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBL2006227.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            21062..22456
                     /gene="uxaC"
                     /locus_tag="LP433_002088"
     CDS             21062..22456
                     /gene="uxaC"
                     /locus_tag="LP433_002088"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBL2006228.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6827 a         4582 c         3903 g         7233 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat tgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttatc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagctt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattaaacgg cgtttatctt
    14521 gttgattctg cggcaataaa atcagccagc agcaaaacat gaagtgctgt tttttgctgt
    14581 cctcttttat tgcttgaatc agatcacaag aaaaacagcc tcttgattca caaatatttt
    14641 tttcgatatt ctcccggcgt aatcgattcc ttctttttaa agaaacgaat aaaattttgc
    14701 ggatttcgat attgcaatct ttctgcaatc tcttttacgg agaggttagt ctctttcaac
    14761 catttttttg ctacctctaa acgatgattt tgaacaaaat caccaaattt ttctcctgtt
    14821 tcctttttaa atacattact taaatagtta gggttataat gcaacctatc agcgatcaca
    14881 tctaaagaca gatcacgatc atattctgtg tagacgatat gcataatatt ctccgacaaa
    14941 tttttaaatt catgatcagt gattgcttga gagcattctg tgattggcag aactaattgt
    15001 tctaaaacaa gtttttctag ttctttggga tgataattgt tcagtgcttt tacataaatt
    15061 tgtttcatgt tatcaaagtt ttttgaatct actcccaata actgtcctaa ttgaacgagt
    15121 tcattgatca agcggaccga aactacttcc cgactcaaag gatttttatt ttgtgcaaac
    15181 aatgcatcaa tcaattcatg tactaaattc ttcacttcct gatttccaga acgaatggct
    15241 tcaaacaatc gattttgttc ttctatcgga tatctaataa gtgttttttc atgagcagca
    15301 ggaacgattt cctgataaaa aataattgaa cttggaccag tatttacacg ataatacagg
    15361 gcttcttttg cccgatcaac cgattgcttg ctttcattca gcgtttcgaa ccggttactg
    15421 atgcctatac tgatagttaa attcaagtat tcttttacac gtttttgaat gagtcggcaa
    15481 tactccatga cttttttgct tgcttctgca tcatctttat ccattcgata aatagtggct
    15541 tgcatttctt cattcaaaac gatcggcagc attcgatttt cctttggcac aatttccgtg
    15601 atcatgttgt tgatcgctaa aagtagcaaa tcacgctccc caccgtgact atcttctaac
    15661 agatcgattt gaaccaaagc tgtataatag cagtcatttt gagaactata accaaattgc
    15721 tgcaaccgct gatctagttc tcgcctttct actcgatttc taaataaact aagtacaaat
    15781 agcgtttcca gctgtggctt ttgggtaact aagtgtgcac ttaacgcttc tttttctcct
    15841 atgatccgac tgactgattg agcgaccaaa tctagttctt tcccactgaa tccttttgat
    15901 ttaagattca gacgttcctg tatttgagaa atcggacggg caaatctgtc cgaaaataag
    15961 taggaaaaaa gaccaatgag tcctaccagt gttaaagaca ctgcaactag cccgattctc
    16021 agattgcgga tcattgcgcc aattgcacta gagtcaactt ctaatctgta aatccaatta
    16081 ttataatctg atttcagtac tatatacgtt ttatcttttt ctcttatcac tttcagctga
    16141 ttgtaatcta gatccacgtc cgttaataca gttggttgct ctttattttt tactgtctga
    16201 gtagtaaaaa ggttgccaac ttcgttttca atagaaagta tgtcttctcc actttcacca
    16261 acaacttgtt ctattgtatg tttctctatc gtagcaattc ccaatgcata tttttctttt
    16321 tcaaacattg gcaaagaaat caccatttcg attcctttgt ttttcttttg ccaaaataaa
    16381 ttatttttgt tatttatgta cttctgttga tacttttcaa cttcctcttc ggtcagttga
    16441 ctcaacgatc cattgattac tccccattta ccagccaaac tgactaaatc ataattatta
    16501 tcatccataa caatcgtttc tataaaattt agttctttcc tgatttcaga ataagtggag
    16561 taatctgtat atgtcagcgg atgcttgaat atgtccgaga aatttttggt cgaaccatac
    16621 gtagaaaacg aatattcaat cgttctaatt ttccattcaa cgttagtttt aacttgcctg
    16681 agcaaattct ttttgtctgt taaataactc gattcgatcg attcataggt attctggtaa
    16741 atgaataaac taaatcctat gacaagtacg gctcctaata aaaacatcgg taaaaatatt
    16801 ttataaaata ctgtactttt cttcattttc ttcctctcct ccttttaaaa taaaaggctt
    16861 tcatttttct gtaaaattga tactcatcta attaaatgag cattccccgc tttcaagaat
    16921 agcataatta aaaataaaaa tccaagtaat ttttaacgtg tgcaatcttt tcatatcaaa
    16981 gatctattga cttatcgtag ttatcgtaat atgatgaatg cgttaacaaa aagtgaaaaa
    17041 gtaaggaaaa tgatggaatg gtaacgatca aagatatcgc taaagcagct ggcgtttctc
    17101 atacgacagt ttctcgtgct ttgaataaca gcagtttaat aaaaaatgaa acaaaacaaa
    17161 aaatacgaca actagctaag gaaatgaatt attcgccaaa ctatagtgca aaaggtttag
    17221 tgaatcaaaa aaaatatcta atcggactat ttttctcaag tttgcataaa ggaacttcat
    17281 caaatttcct agcagattcc attgcaggca tccattcagt attagacaca aattacagtt
    17341 tatctgttga aagtatcgat gttgttgatt taacagaaat caacctgcaa cgctacgatg
    17401 gactgatcgt tatgagtcaa agtgatgatg atcagccttt catcgactat ctcaaagaaa
    17461 aagaatttcc tttcgttgtt gtcaatcgtc acatcaatga tccagcggtt atcaacgtca
    17521 ctgccgatga tgcggccggt gttatgcagg cagtagatta cggtattgga tgcggacata
    17581 cgaagatcgc ttatattggc ggaaagaaaa attttcgttc gacaaaagaa cgggaaaaag
    17641 gggtattgaa aagtctaaaa aaagcgagca tccctgtcaa tctagcctat tttttaacag
    17701 gagattacag cttagaaagc ggcctccaaa acatggaata cctattatca ctttctgacc
    17761 tgcctactct ggttttttgc ggcaacgacg acatagcgat tggtgcattg agagctgtac
    17821 atttagctgg cctccgtgtt ccccagaaca tttctctgat cgggttcgat gattctccag
    17881 tcgtctccta tctcaatccg ccgcttacca ccgtacgtaa gcctttgaaa gaaatgtgtc
    17941 aagaaggaac aaagctttta ctagatttga tcgaaggcag gacgatcgaa caatctaaaa
    18001 ttgagctctc caccttgttg atccttcgtg agtcgatcaa ttacttgtaa actacaagta
    18061 attttatata aaaatgttaa cgtgtgcata acacagaaag gaagtttata tgaaaaaact
    18121 gacaaaagaa ttagtgaaaa aaaacgaagc acctgtaaaa gttcttcagt ttggtgaagg
    18181 caattttatg cgtggattta ttgattggca gattcagcag ctgaataacc aacaattgtt
    18241 taaaggtaat gttgcaatca ttcaaccttt agaacaaggt cttggaaata tgatgaacca
    18301 gcaagataat ttatatacgg tcattttaca aggactcagc aatggcgaaa tcgttgatac
    18361 ttccgagatt atcaccgtag tagaacaaat gatcaatcct tatgatgaat gggatgctta
    18421 tctatctcta gcagaaaatg acgacttggc ctatatcgtc tccaatacaa cagaggcagg
    18481 aatccaattc gtggagactg ataatttaac agatactccc ccacagagct tcccgggcaa
    18541 actgacagcc tttttatacc gacgtttcaa attaaacaaa gctggcttta ccatcattcc
    18601 ttgcgaactg attgacagaa acggcgaacg tctaaaagaa atcattttac gctacgcaga
    18661 aaaatgggat ttagaacctg cttttgttga gtggttagaa aaagaaaatg ttttctgttg
    18721 tagtttagtt gatcgcatcg tcccaggtta tcctcgcgaa gatgcaggtg ttttcaatca
    18781 acggcataac tatgaagatc aattgatggt caaagcagaa ccattcatgc tttgggtgat
    18841 cgaagggcct aaagaattgg agaatcaact accattcaaa caggctggct tgaatgtcat
    18901 catcacagat gatatgactc cttatcgtga acgtaaggtg catttgctta atggaccgca
    18961 tacagcgatg gtccctcttg ctttgttggc ggaattggaa actgtagaag aagtaatgaa
    19021 agatccttta ttctccgcat atgttgatca gttattcaat ctagaattga ttcctatgct
    19081 ttctttacct aaagatgaat tagccattta tgctgaccaa atcaaagaac gtttcttgaa
    19141 tccttttgcc catcacaaat tagaagcgat ttcattaaat agtgtttcaa agttcagcac
    19201 ccgtctgctt ccagtgttca agaagtatat cgaagaacaa aatcaggtac caccgttaat
    19261 cactgtttca ctagctgcgc tacttcttat gtatcgaggc gatcaagtaa agccacatga
    19321 tgatgaaaag acgataagcg aatttactga tgcttggtct gataatggaa cagctattcc
    19381 tcgattattg caaaacgctg cgctttgggg agaagatttg tctcaaatac cgaatgtgac
    19441 agatacagtt caagaaatag ctgcaaagat cgatcaaaaa ggtgtccggt cagtattaca
    19501 agaaatgaaa ggaacgatgg tccatgcttg aaaccctgca accaacaatg aaattaaatc
    19561 gacgagacag tgtggtcgtc gcattaaccc ctattccaaa acaaacacaa ctgacgattg
    19621 atcagcaaac gatcaccact cttgaagata tcccgcaagg tcataagatt gcattgggtg
    19681 atttgaaagc tggagacaac gtgatcaaat atggctatcc aatcggtcat gtgacgacag
    19741 acgtaactgc cggtcaatgg ctgcacactc ataatgtaaa aaccaatctt tctggtgaat
    19801 tggattatcg atatgaaaaa gatgtccatc caagtcatta cctttttgag aaccgaacat
    19861 ttcaaggtta cttgcgaaaa aatggaaaag tagggattcg taatgatttg tttttagtac
    19921 ctaccgttgg gtgtgtgaat ggcattgctg aactgatcgt caaacagttc aaggaaaaac
    19981 atccagatct gggacagttt gaccatatta cgattttaaa gcatccttat ggctgttcgc
    20041 agcttggaaa agatcatcaa aatactcgag aaattttagc ggacgcagta aatcatccca
    20101 atgccggagg agttttagta tttggattag gttgtgagaa caatacagtt cctgaattca
    20161 aaaaaatttt aggtgaatat gatgaagaac gagtgaaatt tctagtggct caagatgttt
    20221 acgatgagat cgaacaaggt gtggctctat tagaagagct tttaacagcg gcggaaaatg
    20281 accagcgcat atcagtcccg ctctctaagt tgaatgtcgg tttgaaatgc ggcggttctg
    20341 atggtctatc gggaataact gctaatcctt tacttggtgc attttctgac tacttgattg
    20401 ctcaaggagg cagcacgatc ttaacagaag tgccagaaat gtttggcgca gaacaagtat
    20461 tgatggcacg agcggaaaat gaagaagttt ttgactcaat cgttgacttg atcaatgact
    20521 tcaaacagta tttcttgtct tacggggaac cagtttacga aaacccatct cctggtaata
    20581 aagcaggtgg gatcactaca ttagaagata agtctttagg ctgcacgcaa aaatcaggaa
    20641 gctctcctgt cgttgatgtg ctacaatatg gcgaaaaaat cagaaaacca gggcttagtt
    20701 tattgcaagc tcccgggaat gatcttgtag ctgcctctgc tcttgcttca tccgattgcc
    20761 agttggtctt gtttaccaca ggaagaggga ctccgtttgg ctcatatgtc ccaacggtca
    20821 aggtatctac gaatacaact ctttttgaac gcaaaggtca ttggatggat tttaatgcag
    20881 gcgtcttatt agaacaacca atggaagtaa tcttagaatc gtttgttcaa aaaatcatcg
    20941 ctgtagctag tggagaagaa acgaaaaatg aacaaaatga cgttcgagaa attgccattt
    21001 ttaaaaacgg agtaacactt tgattttcat aaaacagtat aaaaagaaag aaggaagatt
    21061 tatgttttta tctgatgatt ttttattaaa agacgattgg gcgaaaaagc tttaccattc
    21121 ctacgcaaaa aacatgccca ttattgatta tcactgtcac ttagatccaa aagaaattta
    21181 cgaaaacaac aatttcagca atctgacaga agcttggtta ggaggcgatc attacaaatg
    21241 gcgcttgatg cgagcttgcg gcgtgcctga agaaaaaatc acaggaaatg cttctgattt
    21301 tgaaaaattt ttagcttggt gtcaaaccgt accaaaaatt atcggaaatc cgctttacag
    21361 ttggtcacat cttgaattga agcgtttctt cggtattgac ttgttgataa atgaagaaaa
    21421 tgcagagaaa atttggacac aagcaaatga aattttggca gctcctgatt ttcgccgtcg
    21481 ggaaatcgca aaaaaatcga atgtagaagt gatttgtaca acagatgatc ccgcagacga
    21541 cttgcactat catcagttgc ttgctcatga agaaccagat ttgaaggttc taccttcatt
    21601 ccgtccagat aaagcactca atattgaaaa agaaggattt aatgcatggg tcacactact
    21661 ggaagaagca gctgaccaaa cgatcaccac ctatcaagaa ctgatagaag tcttagggca
    21721 gcggatagaa tacttccatc aacatggatg tcgtgtttcc gaccacgctt tagacatctt
    21781 acgctataaa gaagcggatg aaacagtatt agaagagatt tttcaaaaag cacgagctaa
    21841 caaactatta tcttcagatg aaatcgatgc ttatcttaca gaaacactga tacatttgac
    21901 ccacttctat cattctcata attggacgat gcagctgcac atccatgctt atcgtaactg
    21961 taatacacaa atgttggaaa aattagggcc cgataccggc tatgatggaa tgaatgatct
    22021 ttctttgact attcctctgc aaaaattatt gaaccgtgca gaagaaacgg atcagttgcc
    22081 aaagacgatc ctttattcat tgaatccgaa tgactatcct gcgattttag ctttgatggg
    22141 ctgtttccaa aaagaacaga atggaaaact gcagttaggt tctggatggt ggtacaacga
    22201 tactcgagct ggtatgcgcg atcaattgac acaatttgct gatggtagtg ctttggggaa
    22261 ttttgtcggc atgctgacag attcaagaag tttcctgtcc tacactagac atgaatattt
    22321 ccgtcgtgtt ctttgtgaat ttttaggcga aatggtcatg cgaggagaag cacctgaaga
    22381 tgaacaactt ttaggaagtc tagttcaagc gattagttat acaaatgcta aaaattactt
    22441 tggctttttt gcctaattga ttaatagtaa cagtaacgaa tcaaaaacag gatagtgaaa
    22501 taacggaatc cgtttatcca cgttttagag aagaagacgg accaa
//
LOCUS       DAFELK010000048        21754 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFELK010000048
VERSION     DAFELK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.049"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            139..1041
                     /locus_tag="LP433_002089"
     CDS             139..1041
                     /locus_tag="LP433_002089"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBL2006229.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            1254..3029
                     /locus_tag="LP433_002090"
     CDS             1254..3029
                     /locus_tag="LP433_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBL2006230.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(3095..4681)
                     /locus_tag="LP433_002091"
     CDS             complement(3095..4681)
                     /locus_tag="LP433_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBL2006231.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            4932..5156
                     /locus_tag="LP433_002092"
     CDS             4932..5156
                     /locus_tag="LP433_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBL2006232.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            5298..7049
                     /locus_tag="LP433_002093"
     CDS             5298..7049
                     /locus_tag="LP433_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2006233.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            7049..8833
                     /locus_tag="LP433_002094"
     CDS             7049..8833
                     /locus_tag="LP433_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006234.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANRGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            9159..10010
                     /locus_tag="LP433_002095"
     CDS             9159..10010
                     /locus_tag="LP433_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2006235.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     EKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            10064..11815
                     /locus_tag="LP433_002096"
     CDS             10064..11815
                     /locus_tag="LP433_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2006236.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            11819..11989
                     /locus_tag="LP433_002097"
     CDS             11819..11989
                     /locus_tag="LP433_002097"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2006237.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(12029..12931)
                     /locus_tag="LP433_002098"
     CDS             complement(12029..12931)
                     /locus_tag="LP433_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2006238.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            13162..14565
                     /locus_tag="LP433_002099"
     CDS             13162..14565
                     /locus_tag="LP433_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL2006239.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            14565..15998
                     /locus_tag="LP433_002100"
     CDS             14565..15998
                     /locus_tag="LP433_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL2006240.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            16143..17069
                     /gene="trxB"
                     /locus_tag="LP433_002101"
     CDS             16143..17069
                     /gene="trxB"
                     /locus_tag="LP433_002101"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBL2006241.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            17283..19010
                     /locus_tag="LP433_002102"
     CDS             17283..19010
                     /locus_tag="LP433_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBL2006242.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            19025..19375
                     /locus_tag="LP433_002103"
     CDS             19025..19375
                     /locus_tag="LP433_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL2006243.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(19467..20327)
                     /locus_tag="LP433_002104"
     CDS             complement(19467..20327)
                     /locus_tag="LP433_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBL2006244.1"
                     /translation="MTSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            20419..20847
                     /locus_tag="LP433_002105"
     CDS             20419..20847
                     /locus_tag="LP433_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL2006245.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGKIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            21009..21185
                     /locus_tag="LP433_002106"
     CDS             21009..21185
                     /locus_tag="LP433_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBL2006246.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            21212..21658
                     /locus_tag="LP433_002107"
     CDS             21212..21658
                     /locus_tag="LP433_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBL2006247.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         7087 a         3791 c         4652 g         6224 t
ORIGIN      
        1 tcttaagctt ttctttagag aaaatttcag ttactatgga gaacagggca aagaaaaatc
       61 aatcattttc tttgtatatc atcttaccaa tatataggaa ttgttagtaa caattgcctt
      121 tcaaggagga atccatccat gttattaggc tcacacgtca gcatgagcgg aaagaaaatg
      181 ctgttaggag cagcagaaga agcagccagt tatggatctt cgacttttat gatctataca
      241 ggcgcccctc aaaacactag aagaaaagcc atcgaagaga tgaatattga tgccggaaaa
      301 gcgtacatgg cagaaaaagg tctaacaaat atcgtcgttc atgcccctta tatcattaat
      361 ttggggaata cgatcaaacc agaaatgttt ccttttgccg tccaatttct gagagaagag
      421 attgttcgtg cggaagcttt aggcgctact caaattacac ttcacccagg tgctcatgta
      481 ggggcaggaa cagaagccgg aattgctaga attattgaag gcttgaatga agttttgaca
      541 aaagaacaga cggcacaaat cgctttggag acaatggcag gtaaaggtac ggaaatcggt
      601 cgaacatttg aggaattagc gcaaatcatc gatggagtaa aattgaatga aaaattatcc
      661 gttacttttg acacctgtca tacgaatgat gccggttata atattaaaga agacttttca
      721 ggtgtaatgg aagagtttga taagatcatc gggttagatc ggcttaaagt actccatatc
      781 aatgattcta aaaatccgca aggttcgcat aaagaccggc acgccaatat tggttttgga
      841 acaatcggat tcgacacgct gaataagatc gtccatgatc caatgtttga caatatttcg
      901 aaaatcttgg aaactcccta tgtaggcaaa gataaaaaga aagcttacgc accatatgga
      961 aaagaaatcg ccatgttcaa agcgcaaaca ttcgatccag aagtgtttcc tgagttatta
     1021 gcagaagaag tgatactcta agattttcta tctgacagca gcaaaaaagg accaggcaca
     1081 ttgccttgtc cttttttgtt taagaaacaa aggagtactt tttgcagtct ttttcatcat
     1141 gcatcttctc ccccctcttt ttaaatttag acaaacaagg tatactggta gaaaagtaaa
     1201 aaaacgaaaa gtttcacaag caagtggcaa aacgtgattg gaaggacgaa aagatgctga
     1261 acactttaaa acccttgatc aaccaactaa aaaagaaaca tacatacttt attcttggca
     1321 tagccctatt atttacaatt attcgtttgt atttatatag taaagcaatc tatggaacag
     1381 acatgtcggc aacctatgat gaccagctgc tgattcgcta tgctcaaaat attttggacg
     1441 gtaaatggct aggggagtat acgactacaa cactttccaa aggaatctcc tacagcttat
     1501 ttttagtact tgcacataaa ctgcatcttt cttatgcagt tttgttcggc atgttcagta
     1561 tttttgccag tatattggtt gcactcgcgt ttaaaccgat tgtgaagaac aagtatcttc
     1621 ttttaagtat ctatttttat tttttgtttt ctccgattag ttttacacat gaatattcca
     1681 ctcgaacata tcgtaatgcc ctcgtgattc cggctgttga gatcattatc gcttgtttat
     1741 tagctattta ttaccgcaaa tacggttcta gcagaaaatt gctgccatgg tttttagggc
     1801 tttctgtcgc ttttcctttc ttttggttca ttcgcgaaga ttctatctgg cttcttcctt
     1861 ttactgtagt agctttgggt atcagtttcg tccagatctt gctagggcaa gacttttctt
     1921 tcaaagaagt aaagaagtta aaaaaacgac tctttcttct ctcgaaacgg gaatggctga
     1981 aactttcatt gtttttactt cctatagttg gcttttccat cgtctatcaa tggatcgaat
     2041 ataaaaatga gacaacatac ggtattgcaa ccatcaatga ccgttccagt ggagaatttg
     2101 gacgtttgat gaaacaactg atccgaatag atgatgaaac gaacttgaat aaagaaaaca
     2161 gtgagatatg ggtctcacat gctgcactaa ataaagcatt agccgcatct cctacattcc
     2221 atactgtttc tacccgtatt gacgaattat atacgactca cgcgtggact caaggtggaa
     2281 aagtaaaaga attacccgga gatatcatct tttgggcatt gcgagatgtg gtaagcgaat
     2341 ctggttatta ccaaaacaat gcaaaagaaa ccaatgattt ttggaaaaaa gtcaaccaag
     2401 aattagaaga agcctatcac aagggaacaa tcaaaaagaa aaaagagttc tatctgatgg
     2461 gatcaggaga tggaaagacg atgagtgatc tgccaatcgt attcgatttc cttcaatcag
     2521 gatacgctta tgcatggcga tataaagatt tccatcaagg aggaaattat agtttcggaa
     2581 cgcaagaaca agtcaaacag gctcaagaat tattaaacct tccgctaatg gagaattgga
     2641 tcgatagtaa tgaaccgaga acacctaatt tccaattaac aaaatcagca aaagtcgcga
     2701 atgtcatcat aaaaatttac caagttctgg ctattcccgt gctgattgct tcaatagcag
     2761 ggatattact tatgatacta ggaaccgtat ttgcaaaagc tgatcgtgcc tattatagtt
     2821 cctctttgat tgtggtcacc ggattaatac tgacacaatt ggtttttctt ttcggtgtct
     2881 catggttttg ttcttatgcg ccagaaaaaa aggactattt tttaagtgtc tacactggtg
     2941 caggcgtgcc attaacgcaa ttcatcgtag taacaagcat gctagttttc agtaaattaa
     3001 atctgaaaaa agctttatct tctaaataaa aagacccttg gtagctagat ttttaaccta
     3061 actatcaagg gtctttgtgt ggaaaaatca gtttttattc gatttcttct accgtttcct
     3121 gcaaaagctg ttcatatttt ttgtttcctt tatataaatc accaatcgtc catgccaaca
     3181 ggagaaggac aagaacaatg attacataag cgatgtgatc agccaatgct agttgagcgg
     3241 aagtggcttg ctcgccgaag aaactttcga tctgtcctgg taatcctcgt aagttcaagt
     3301 aagttagact aatcacagag aaccagccaa gaagttttac gatgaatgaa tttttaaatc
     3361 ggctacccat ctccgcttgg ctgttggtca tcatcagtaa aggaatcatc gaaaacggca
     3421 acgcaaaagc caagaacacc tgggattcat tcattaagtt attcaaagcg gcatgttctt
     3481 cgatcgttcc ttttgtactt gtaaacaaaa cacaaatcaa tacaggaatc acagaaagca
     3541 atcgtgtgac cagtcttctt agccaaatcg ggatacgcat atggatgaat ccttccatga
     3601 tgacttgacc ggtcaacgta ccagtaatag tagagttctg gccagaagca agaagtgcta
     3661 cagcaaataa agtggacaag ataccagatt ttgctacagc aatcaaaata ccattgctca
     3721 tagctgatgg atcagataaa gcttcataca gaccaaaaaa ggaaggatct tggacagaac
     3781 cggttttgaa gacagcgaca cccatgatca atagcagtgc attgactaga aaagccattg
     3841 acaactggat attagaatcc caagtagaaa aacgtacagc ttgtgctaca tcttcttcgt
     3901 tttggtgatc gatcttccga gtttgtgaaa ctgctgaatg aagatataag ttatgcggca
     3961 tgactgttgc accaataatc cctaaagctc cagtcagcgg agtttcgccg ccgatgaccg
     4021 gtgagtctga gaatgtatga ctgttaggga taaagccagc aaataaactg tgccaatctg
     4081 ggttagacaa gccaacttga tagacaaaaa cgaataaaat gacgaaaatt aagcagacaa
     4141 ccagtgcttc gatcttacga aacccgactt ttgtcagtag taagagaacg aaaacatcta
     4201 atacagtaat aaagacggca atcaccaatg gaatatcaaa aagtaagtag agggcgattg
     4261 ctgcaccaat gacttctgca atatctgttg ccataatggc taattcagtc aagatccata
     4321 aaatgacacc taatgtctta cttgtgcgtg ctcggattgc ctgtgccaaa tccatttggc
     4381 tcacgattcc taattttgct gccatatact gtaaaagcat agcaatcaga ctagacatca
     4441 aaataactga catcaataaa tattggaaat tttgtcctcc ggtgatcgaa gtagaccagt
     4501 tacccgggtc catataccca actgctacta acgcaccagg tccagagtaa gcaagaagtg
     4561 ttttaaaaaa acttttcccc tttggtacat caactgttcc atttacttca gctaaagata
     4621 aaccatttgt atgttcaata agtcgatgct tatgaaattg tttattggat tgattattca
     4681 agaaaaaacc acctttccta tttatctacg attacattct acacctcaaa aagaaaaaat
     4741 taaagaaaaa gattcggtac gcctaatttt ttttcatggc gcgtcttgct agatgacgaa
     4801 agaaattttg ttctcctcta aaaaaaccac tattttttgc atgaaactaa agaatacgcc
     4861 tttctttttt caataaactt tagtaaaata agtcattgag agcaattcgg aaatagaaag
     4921 gagagattta tatgttatca acaggtattg tcgtacttat tgctattatt gctttgctaa
     4981 tcggcgcagt aggtggcttt ttcctagcgc gtaaatatat gaaagactat ttagaaaaaa
     5041 atcctcccgt taatgaggac atgttgcgat caatgatgat gtcaatgggg caaaaaccat
     5101 ctgagaagaa aattcgccag atgatgcagc aaatgaagaa ccaagggaaa aaataggttc
     5161 tgacccaacg actttttacg ggctgatttt ttcagtccgt tttttatttc gtaatttgtt
     5221 agactattca gattattcag caaaaaagac aagcacagac aatcctaggc tcttgataaa
     5281 gacaaaggag gagtaaaatg tcgattttta gaaaattagg ctggtttttt cgtcaggaaa
     5341 agaaacatta tttaattggg gttttctcgc tattcgcagt ggccttggta cagttagttc
     5401 ctccaaaagt gattgggatc atcattgatg agatcgccga taaaaattta tcaataaaga
     5461 tcattttcgg gtggatcttc ctattgatta tcgctgcttt tttacaatat ctttttcgtt
     5521 atatctggcg gacgaatatt tggggaagtg cagctcgatt ggagaaagaa cttcggcagc
     5581 agttattcaa acattttaca gaaatggaca atctctttta ccaaaaatat cggactgggg
     5641 atttgatggc tcacgcaacg aatgatttga atgcgatcca gaatgtagca ggagctggta
     5701 tcttgacctt tgcagattca gtgattacgg gcggaacaac gatcattgcg atgattttgt
     5761 ttattgattg gcgcttaaca ctgattgcgc tgattcctct gcctttgctg gccgtcactt
     5821 cacgagtgct ggggtcaaaa ctccatgatg cttttcgtga ttcgcaagaa gctttttcta
     5881 gtatcaatga taagacacaa gaaagtatca ctgggatcaa agtcattaaa acatttggac
     5941 aagaaaaaga agatctagcg gattttgaag aaaagattga agatgcaatt attaaaaaca
     6001 aacgagtcaa ttttttagac tccttatttg atccattcat taccttgatt atcggtctgt
     6061 cttatgttgc aacaattatt ttaggtggaa agtatgtctt ggaaggcacg atctcgatcg
     6121 ggcagatggt ctcatttatt agttatatcg gtatgcttgt ttggccgatg tttgcgattg
     6181 gtcgattgtt caacgtattg gaaagaggaa atgcttctta tgatcgcgtc aatgaacttt
     6241 tgcatgaaaa gacgcatatc gtggaacaac tgggtgcagt gcagaccccg gcaaaaggcg
     6301 agctgaatgt agctatttcc tcttttaatt atccgaaaga agaatcacca gcattagaac
     6361 aaatcaagtt tgcgatccaa gaaggagaaa cattaggtat tgttgggaaa actggtgcgg
     6421 gaaaaacgac gatcatcaaa ttactgatgc gtgaatacga tgattatcaa gggaaaatcc
     6481 aatttggcgg acgttcgatc aaagaatatt cattgaatgc tttattagga tcaatcggct
     6541 atgtgcctca ggatcacttc ttgttttcga tgaccattcg agataatatc cgtttttcta
     6601 atccaaaact ttcagaagaa gaagtagagc atgcggcttc tttagcattt atcaacaatg
     6661 aaatcaagga attaccaaaa ggttatgata ccttagttgg agaacgtgga gtctctttat
     6721 ctggcggaca gaaacaaagg atttcgattg ctcgagcatt gatcaaaaat cctgaattat
     6781 taatattaga tgatgcactc tctgcagtag atgccaaaac agaagaagct atcttgcata
     6841 atttaaaaga aataagaaaa gagaaaacaa ctatcattgc agctcaccgt ttaagtagcg
     6901 tgatgcatgc aaaagaaatc attgttgtcg atcaagggaa aatcattgaa cgaggaaccc
     6961 atcatgagct gcttgcacta ggcggctggt atgaacaaat gtgggagaaa cagcaattag
     7021 aagcgaagat agaaggaggc gaggcctgat ggatgaaaat tatcaatcgg aatggacaaa
     7081 atcgattcca cttaaagaac agaaaaagat catcaaacga ctgatgaagt tcgccaaacc
     7141 ttttagaaga acgttcatcg ttgctatctt atttgcgttt gctttgtctg tgatcaatgt
     7201 cctattgcca aggatcatcc aaacttttat ggatgatcat ctggctaaac agtcggctac
     7261 gacacaagtt attttgtttt ttgctggtat gtacttattt ggagtcatag taaaaagtat
     7321 catttggttt ttccaatggt atttgtattc catggcctca ttgaagacct atcagtatat
     7381 tagggtaaaa ttatttgaaa agctgcatac actaggtatg cgttattttg atcagacacc
     7441 ggcaggatca accgtttctc gagtgacgaa tgacacagaa acgctatttg aattttggta
     7501 cgtctttttg atggtattga ctgggatctt tgcagtcgtt tcttcattcc ttgccatgtt
     7561 tcaaatcaat ggagaaattg ccttgtggac tttggtgttt ttgccgattt taggaatcgt
     7621 catctggtat taccagaaat tcagttctcg tatttaccga aatatgcggg aaaaattaag
     7681 tcagctgaac acgaaattga atgaatcgat ttccggcatg cgtattatcc agcagtttcg
     7741 ccaagaagct cgtttagcta aagaatttga acaagtgaac aatgagtatt tagacacgcg
     7801 ttatgcgatg atcaaaacga attcgattct gttaagtccg atcatcaatt ttctatatgc
     7861 attggcgatt gcgttggtgt tgactttgtt tgggatcgat gcgttgcatt ctcccgtaga
     7921 agttggactg atctatgcat ttacgaccta tgtccaggga ttttttaatc caatgtctca
     7981 aatgatggac tttttgagca tcttcacaga tgggatggtt gctggtagtc gtatcttgaa
     8041 gattatggat acggaagaat atgcaccaca acaaaaccct ggagcagatc aaatgattac
     8101 ttcaggtaag attgagtttc gcaatgtaag cttttcttat gatggagagc acaatgtatt
     8161 aaacaatatc tcttttgttg ctaatcgggg agagaccgtt gcattagtgg gacacaccgg
     8221 aagcggaaaa agctcgatca tcaacgtatt gatgcggttt tacgaatttt atgaaggtca
     8281 gatattgatt gatgatcatg acattcgaga atatccaatg gaagagttac gtaagaaaat
     8341 ggggctggtc ttgcaagatg ctttcttgtt ttatggggat atcgcaggaa atattcggat
     8401 gatgaatcca gctatcacag acgaacagat acgccatgcg gctgagtttg ttcaagcaaa
     8461 caaattcatc gatgaattac caaaaggata tcactcaaaa gtgatcgaac atggtgccag
     8521 ctattctagt ggacaacgac agctgatcac ttttgcgcga acaatcgtga ctgatcctaa
     8581 aattctagta ttggatgaag caacagcaaa tatcgatact gaaacagaag gattgatcca
     8641 agaaggattg gcaaaaatgc gtcaaggacg gacaacgatt gcgattgccc atcggctgtc
     8701 aacgattcga gatgcagaat tgattttagt tttagacaaa ggtcatatag tagaacgcgg
     8761 gaatcatgaa acacttctag cgcaaaatgg tttgtatgca gatatgtaca aactgcaaag
     8821 cagtggtata taaaagatgt tgtgacagta gaattttgac ctaagcacta gagtgaaaat
     8881 aaaacatagc ttctcatatt tttcatctgt gagagttagt gtcgtagtca ccagatttaa
     8941 aaaaagattc gacagctagt cagaagtgcc taatagccac taagaaagcg ttgacaaaag
     9001 catttgcttt cgataatata aagaaaacga tacaacttgg atagtgattg cctgatgcaa
     9061 gctaaacctg atgagtctcc catggtttca tggacggctt tttgggtttt tctttttgtt
     9121 ttggatacag ccctatacat catggaaagg agcaaaacat gctgattgag aaagtactga
     9181 ataacaacgt cgtaataacc agggatgaaa gaaatcagga aatgatcgtg atgggaaaag
     9241 gtttggcatt caaaaagaaa gtgggtgacc cgatttttga ctcatgcatc gaaaaaaaat
     9301 ttcagttgac aaatgacggg ctttcacaac agttccaaga attggcacaa gcgattcctc
     9361 ttgagtactt agaaatttct tgtgaaatca ttgaatatac aaaagaggct ctacaagtcc
     9421 agttgaatga ttctgtgtat attgcattga cggatcattt gtatacggct atcgaacgtc
     9481 acaaaatggg aatatttgta ccaaatgtat tgctgtatga tatcaaacaa ctatttccta
     9541 aagagtatgc catcgggaaa aaaacagtga agaaaatctc ggataaatac cacatcaagt
     9601 tatcagaaga tgaagccgga tttatcgcat tgcatttagt caatgcacaa ggcattcaaa
     9661 gccagcaaga caatacctac ctgtttacta taacaataca ggatattcta aatatcgtcc
     9721 gctattacta taagattaca tttgatgaag attcagtcca tttttttcga ttcgtcacac
     9781 acttacgttt ttttctgaca cgcgtcctag atggagaaaa atcagaagtg ggagaagttt
     9841 ctgaggaatt gtttcaggtt attcaaaaaa aatataagga tacgtttggt tgcgttgaga
     9901 aaatagcaga ctttttagcc gagacgttca actaccagat gtccacggac gaaaaaatgt
     9961 atttaacgat ccatactgcg cgtttagtgc atgagaatcg ttgtaaataa aaaaaggagg
    10021 ataaattaac aagaacgtat gaaataaggg tagtgacatt cagttggcta aaccttccac
    10081 taataaattg gagggaatag aaatgggaaa ataccaagaa ttagcgagaa aaatcgtaga
    10141 aaatgtcggc gggaaggaaa atatcaatgg tttgacacat tgtatcacaa ggcttcgttt
    10201 caaattaaaa aacgaagaaa aagcaaatga tgagatcttg aaaaatatgg acggtattgt
    10261 aacggtaatg cgagcgggag ggcagtatca agttgtcatt gggaatcatg tgccagtcgt
    10321 gtttgaagag gttataaaag caggaaacct tacttttgat gaggctgttt caacagaaaa
    10381 aatgagaccg tttgatatgc ttattgatgg aatatcgggc tgtttccagc cattccttgc
    10441 tatcctagct gctggcggga tgattcgtgg actgacagca ttccttgtct tcttaggcgc
    10501 gtttgaccgc ggttctggca catttgttat gtttgataat atcggtgatt ctgtattcca
    10561 atttatgcct gttattatcg gtttaacagc tgcccgtaaa tttaaagtaa atgaattcgt
    10621 agggatgttg cttggcgcag cattaatgaa tcctagcttg tcgctggaag ctttgagtgg
    10681 tgcagcagaa gcaccactaa cgaccatatt ttctggcact atttttgaag cacctattta
    10741 tcaaacagta ttcggcattc cctggattgc gcgtaactac gcttcttctg tcattcccat
    10801 tatctttatt gtgttgttag ctagccaaat tcagaaacca attaaaaagt tagtacctga
    10861 gatgatcgcg aatttcttcg ttccattctt caccgttctt attacaatgc ctttaggttt
    10921 tttactcgtt ggaccagtat tcacattcgc aactgatatt ttaatggctg gatttgaaac
    10981 acttttagca ctttcgccag ttatttatgg agcaatcgta ggcttcttct ggcaaattct
    11041 ggtgatgttt ggtctccatt gggcaatcgt accaatggga ttgatgcaat tttctgtgaa
    11101 tggttggcaa aatattatga cacctgttgc agtagtgtct tttggacaaa ctgcagcact
    11161 taccgcactc tactttaagc ttagaaatcc aaaagacaaa gcaattgcaa taccagccat
    11221 tgtttctggt attgtgggga ttacagagcc agctatttat gggtttacat taccacgtaa
    11281 aaaaatattt atttttacct gtgtcggtgg tgcgttaggg ggcgcgtata gtgggttaat
    11341 gaatttaact tcttggaatc aaggtggact aggcatcttt acaattccca actatattag
    11401 accagatggt gatttaacag atgtgattaa tgtattgatt gggatcgcca ttgcgatggt
    11461 ggtatccttt acgctgactt ttttcttttg gaaggatgaa gcaggtgaaa cagatgatat
    11521 acagaaaaaa tcaggtaaag aaattgtaaa aacaccgata caaggacaaa tcgctccact
    11581 aaatgcagca aaggatgcag cttttgcaca aggaacacta ggtcgaggaa tcttgatcta
    11641 ccctgaaaaa ggagaagtac gtgccccttt tgacggaaca gtcatgaccc tgttcccgac
    11701 gaaacaggca attggaatgg tttctgaaac agggctggaa ttgctgattc atgtcggatt
    11761 ggatactgtg cagttggaag ggaaatattt tgaaagctta gtgcagcaag gataaagagt
    11821 gaaacaaggc gatctgttgc tacgcttcga caaaaagaaa atcgaaaagg aaggatacag
    11881 tttagaaaca cctgtgatcg tcaccaatta cacggattat ttggatattt tggaaaacca
    11941 aggggagacg gtcgggccag acgatgcact tatcaccgca ctgacctgaa cggttaggtg
    12001 aagaatggac taggcttaac tattcttttt attccacttc tttattttca aaattgaaag
    12061 gctctttcat gatggctgag ctgatagggc gtttatcgaa tttttgaccg acagaaatta
    12121 gatggactaa attctgttga taattttctg caaaaacaca actatataac acgtctagaa
    12181 gataacaaat tgatgtattg atcgtaaaat taccaatttt tgaatacagt cgctcgcgtg
    12241 tcgtaagtcg caaagcggct gtactcattg cagatagcgt tgaatcaccg atactggtca
    12301 aagctaaaat tggaacatga ttttgtttca atatttctgc ggtacgaagg atcacattgt
    12361 tttcacccgt ataagaaatc agaatcccgc acatatcact cgtgcaattg tacgcttcat
    12421 agaatgattc accaaaagtg gtgacaatcg tgacatccat tttgatgcgc ttcattttca
    12481 gcatgaaatc ttgagaaatc aaagtattcg agttactggc gaaaatcacg attttttttg
    12541 cttgaagcat tagttgtttg gctttttgca gttggtcatg atgaatgaga gaaagtgtat
    12601 catgaatcgt catctgttct aaagaagcca ttttatttgc gatcgtcata ataccgtctg
    12661 tggtggaaaa aggaagattc gcatctacgt cttgaaaatt cccttcaaga taggctgttt
    12721 cagctaaaaa agcattacga aaactgaccc agccatcaaa acccattttt tttgctacac
    12781 ggatgagtgt agaggggtgg acataacatc gctcagcaat cgcttggatg gtcatttcgc
    12841 caagtgctgg agaatcgctt aagagaaact ggatcacttc attttctgaa ggagaaaagg
    12901 agatttcttt gattttttca cgtaataaca tgtagatacc ttcttcttat ttttttacgt
    12961 aaattataac ttttttgaaa atgatttgta aacggattta tactatataa cttaaaatag
    13021 acattttttg acaagatatt tacaaaaatc cactagaaaa cagtaaattt tgtaaatgtt
    13081 actggaaaga aacagatttc tattgtttgt tttgtttaca aaaaagataa tgaaagtgta
    13141 aaaaagtaaa ggagtgagaa catggcaaaa ggaatcaaaa tcgctacgat tggtggaggc
    13201 agcagttaca cccccgagtt gatggaagga tttatcaaaa gatatgagga attaccgata
    13261 cgagaaatct ggctcgtaga tgtagaagaa ggaaaagaaa agcttgagat cgttagtcag
    13321 atgtctcagc gtatgtggga tgcttctccg tatgaagtca agatctatgc aactctggat
    13381 cgggaagaag cattgaaaga tgcggatttt gttacgactc agtttcgtgt cggtcaatta
    13441 gatgcacgaa tcaaagacga gcggatccct agttattatg ggatgattgg gcaagaaaca
    13501 aatggtgctg gcgggatatt caaagctttt cgtaccgttc cagtcgtttt ggcaatcgtt
    13561 gaggacatga agcgtttatg tccaaatgct tggctgatca atttcgcgaa cccaagtggg
    13621 atggtgacag aagcagttat cagatatggc aaatgggata aagtgattgg attatgcaat
    13681 gtgccagtga tggcgatgat gacagaacca gcaatgcttg gcaagaaaaa agaagagctg
    13741 atctacaagt ttgccggtct aaatcatttc cattggcaca aagtagcaga taataaagga
    13801 aatgaccgca cggcagaatt gattgatcgt ttatacgatg aagagaatgg attaccgaaa
    13861 aatatctttg atatcccgtt tttcaaagaa caattaaaac aaatgaacat gatcccttgt
    13921 ggctaccacc gctattacta tcgtgaagaa gaaatgctgg aacatgcttt agaagaatat
    13981 caaacgattg gtacaagagc gcagcaagtg aaagaaacag aagcagagct atttgaatta
    14041 tacaaagatc cagaattaga ccataaacct gaacaattgc aaaaacgagg tggcgcttat
    14101 tattcagacg ctgcctgtga aacgattgct tcaatctatg gaaataaaga aacacagatc
    14161 gtggtatcta caaagaatga tggagctgtt cctgacctgc cggcagattg tgtagtagaa
    14221 gtcactgcct atgttggcgc acaaggagcg agaaatgtag cgtttggttc tcttcctgct
    14281 gctgaaagag gctggttgca agtaatgaag aatatggaat tgctgacgat cgaagcagct
    14341 gtgactggtg attatgggac agctttacag gcgtttacga tcaatccact tatacgatca
    14401 ggaaagacag caaaacggat catggatgag ttgtttattg cacaccagca gtatttaccg
    14461 caattcaagg agacaatcag ccgattaaaa gaagaaggaa tcgaagttca agatgaactg
    14521 gcaagagaat tatcaggtaa tacacatata atggaggaag tataatggga ttcagaaaag
    14581 attttttatg gggcggtgct acagcagcca atcaatgtga gggcggttat gatgaaggtg
    14641 gacgcggact agcaaacgta gatgttgtgc caatcggaaa agaccgtttt cctgttatca
    14701 ccggaaagaa aaaaatgttt gaatttgatg aggatcattt ttatccagca aaaattgcaa
    14761 tcgatatgta tcatcgttat aaagaagata ttgctttgtt tgcagaaatg gggttcaaga
    14821 cttatcgaat gtccatcgcc tggagtcgta tttttccaat gggggatgag aaagagccga
    14881 atgaagctgg cttgaaattt tatgaggatg cctttaaaga atgccaaaag cacggaattg
    14941 agccacttgt gacgattacg cattttgatt gtccaatgca tttgatcaaa gaatatggtg
    15001 cgtggcgttc cagagaactc gttggttttt atgaaaatct gtgtcgagtc atcttcaatc
    15061 gctataaagg acttgtcaaa tattggctga cattcaatga gatcaatatg atccttcatg
    15121 caccattcat gggcgcaggg ctgtattttg aaaaaggaga aaatgaagaa caaatcaaat
    15181 atcaagcggc acatcatgag ttggttgcaa gtgccatcgc aacgaagatt gctcatgaag
    15241 tagatccgga gaacaaagta ggctgtatgc tggcagcagg agcatattat ccatacactt
    15301 gcaatcctga agatgtttgg gcttctagaa aatcagatcg agaaaattat ttcttcattg
    15361 atgtccagtc acgaggagaa tatcccgctt atgcattgaa agaaatggag cgaaatggca
    15421 ttcagatcga aatggaacca ggggatgccg cattgctgaa agaacatact gttgatttta
    15481 tctctttttc ttattatgct tcccgagttt cgactaccga caacgaactc ttggaacaga
    15541 ctgcaggaaa tatctttgct tctgtcaaaa atccatatct gcaagcaagt gaatgggggt
    15601 ggcaaattga tccattaggc ttgagaataa cgatgaatga tatttatgat cgttatcaaa
    15661 aaccattgtt tattgtagaa aacggcttag gtgcagtcga tacgccagat gaaaatggtt
    15721 atgtggaaga tgattaccga atcgattacc tggcagcgca tatccaggcg atgaaggatg
    15781 cagtagaact agacggagtc gatctattag gctatacgac ttggggatgt attgatttag
    15841 tatcagctgg taccggtgag atgaagaaaa ggtacggatt catttatgtc gatcgtgata
    15901 accaaggaaa tggcacatta gcccgttcaa agaaaaaatc attcaactgg tataaaaaag
    15961 taattgattc aaatggagaa aatctttcga acgattgatc aatgatttat aaaagtctat
    16021 tgtttttcag cggatttttc gagtataata aagctattcg agaaacgcaa gcagaacaat
    16081 agactttttt tcgcattggc tgtaaagtat gcttacttga ttaagtaaag gagaatctac
    16141 atatgtatga tgtaatcgtt attggcgcag gtcctgctgg gatgactgct gctttatatg
    16201 cttcacgttc aaacttatcc gtattgatga tcgaacaagg tgcccctggc ggccaaatga
    16261 acaatacggc agaaatcgaa aattatcctg gattcgattc gatcatgggc cccgatctag
    16321 cttataagat gtatgaaagt gtctcaagat ttgggacaga aaatgcttat ggaatcgttc
    16381 aagatatcaa ggatcacggc agccataaag aagtcatctg tgaagataaa agttacgaag
    16441 gaaaaacagt cattatcgca acaggatgta tccaccgtaa attaggcgta cctggcgagg
    16501 aagaatttgc tggacgaggc gtttcttact gtgcagtctg tgatggtgcg tttttccgta
    16561 acaaacgtct agtagtcatc gggggtgggg actcagcagt agaagaagcc atctatttga
    16621 cacaatttgc ttctgaagta gtgatcgtcc accgtagaga tgaattacgt gcacaaaaga
    16681 tcatccaaga ccgtgcattt gcaaatgaaa aaatttcctt tatgtgggat acagtcgttg
    16741 acgaaatcgt tggaaacgaa atggtagtga caggtgtgaa agcacgtaat gtcaaaaccg
    16801 gcaatgaatt tgatttagca gcagacggag tattcatcta tgttggactg gatccattaa
    16861 ctgcaccttt tagagaagca ggtttgacga acgaagctgg ctggattcca acagacaacg
    16921 aaatgaaaac gaatatgcca ggcgtttttg ccatcggaga tgttcgtgaa aaagatttgc
    16981 gacaaatcac tacagctgtt ggtgacggcg gtattgctgg acaacaagtg tataaatact
    17041 tggagtcttt agaagaaaca acagcataag tttaaaaaga gtagaagaac gggttcaatt
    17101 gttcttttac tctttttttt cgcgtgaaat ttactgaatc tgatttatgc gaacacgtcc
    17161 aacacctttt gataaaagaa tcctttcttg atttaagcgt tttttggtcc tcatactttc
    17221 atatctaata agtgaatgct atacttatta agaaccatat ttcagaaaga ggtgttattt
    17281 tcatgtcttg ggaacaagtg tatgaacaat gggtacatga agaaaattta gaagaaaact
    17341 taaaaaaaca attaaatgat ctgggtgaag atcctgaaaa acttgaagat gctttttatg
    17401 caccgttgga attcggtact gcaggtatgc ggggaatctt aggacctggg atcaatcgaa
    17461 tgaacatcta tacggtaaga caagcaacag aaggactagc acgtttcatg gatacacaag
    17521 gtgaagaaac aaaacgccga ggtgtcgcta tcgcttatga ctcacgccat cagtcaccag
    17581 aatttgcaat ggaagcagcc aaaacactag cacatcacaa tatcccgtct tatgtattcg
    17641 aaagtctgcg tccaacacca gagctttctt ttgcagttcg tcatttgaag acgtttgcgg
    17701 gaatcatggt aaccgcatct cacaacccag cggcttacaa tggatataaa gtctacggag
    17761 aagatggcgg acaaatgcct cctgcagacg cagatgcatt gacgaaatat gtccgtgaag
    17821 tcagcaatcc gctaaaagtc gaagtattat ctgacgaaga agctaaacat agcgggttga
    17881 tcacgatcat cggagaagaa gtggacgctg cttatctaga agaaatcaaa gcagtgacga
    17941 ttgatcgtga attggttgaa acaatgggga aagatttgaa acttgtgtac acgccacttc
    18001 atggaacagg gaaaatgttg ggcgaacgtg cgttgaaaca agctggattc gaacaattcg
    18061 tactagttcc cgaacaagct gtggcagatc cagatttcac tacggtcaaa tcgccaaatc
    18121 cagaagaaca ttcagctttt gaatatgcta tacgacttgg agaaaaagaa ggagctgact
    18181 tgctgattgc aacagatcct gatgcagacc gtttaggcgc agcggttcgt ttgccagatg
    18241 gttcttatga agtattgact gggaaccaaa tcggagcatt gtttgctcaa tatattttgg
    18301 aagcacatca atcaagaggc actttaccag aaaacgcagc ggtattgaaa tcaatcgttt
    18361 ccagcgaatt gcctacagca attgcggaac actacggtgc taccatgttc aatgtgttga
    18421 cagggtttaa attcattgct gaaaaaatcc aacaatttga agaagaccat tcacatactt
    18481 ttatgtttgg attcgaagaa agttatggtt atttagttaa accttttgtt cgcgataaag
    18541 acgcgatcca agcattgctt ttattagcag aagtagcagc ttactataaa aaacaaggca
    18601 aaacgttgta tgacggcttg caaacgattt ttgaaaccta tggctatttc gcagaaaaaa
    18661 cgatttctgt gacaatgagc ggacaagaag gttctgcgaa aatctctgct ttgatggaaa
    18721 aattccgtaa agaagcaccg acagaatttg ccggagcaaa agttattcaa acagaagact
    18781 ttaaagaatt gacgagaaca gaccgtgaag gaaacgtaga aaaactaaca acaccgccat
    18841 ccgacgtatt gaagtataca ttggaagaaa atggctggat tgctatccgc ccttcaggaa
    18901 ctgagccgaa aatcaagttt tatattggtg taaaaggaag ttctacagaa gacgcagccg
    18961 aaaaagtagc ctcttatgaa gcgattatca aaaagatgac agaagaataa aaaacttgag
    19021 actgatggaa aaagtggtaa actttagaag tcagtctttt ttcaagttgg aggtgaatgg
    19081 attgccagac acgcaaaaat caaaagtaga gaaagtcagt caattattca aaatgttgag
    19141 tgatcccact cgtcttaaaa ttctgctata tctgaaagac ggggaacaaa atgtgacagc
    19201 aatcacccaa gcagtggaaa tggagcagtc tgctgtatcg catcaactac gtttattaag
    19261 agaaaatcat gtcgtcaagt ctcatcgcga gggaaaagcg attttgtata gtcttgatga
    19321 ttctcatgta ctggatattt tgaaccagac actcaaacat gtggaacatc aataacgata
    19381 ggtgcaaata gataaacact ggagtgtgac aacgaagaaa tttcgttgtc acactccagt
    19441 gttttttaag aaaaagacaa aaatgatcaa tcgctttttt ctgttgtttc agttccataa
    19501 taactatgat cttctaggtc taaagcattc aaaataagcg aagccgtttc ttcaatagat
    19561 aaagatgcta cattgatcac tacacatcct agtttttcat aaagatcatt cgcaaaatcg
    19621 agttcagctc taattttttc gatatcggaa taagcagtat cagggtttaa tccgtaagag
    19681 cgcatccgtt ctttacggat attatttaaa atatctgggt tatttgttag tcccacgatt
    19741 tttttaggat cgatctccca aagctgtttg ggaatatgtg cttgtgggat caaaggtaaa
    19801 ttggcaactt ttaaattttt gttagctaaa aacaagctca aaggcgtttt ggaagttcgg
    19861 gatacgccta gcaaaacgac atctgcttct aaaaaaccac gaggatcttt cccatcatcg
    19921 tattttacag caaattccat tgctttgatc cgtttgaaat agttctcatt caataaatgg
    19981 agggcaccag gttgccgaat tggcttgata ccagttaaac gttcaatttc tgatatcggt
    20041 ggcgtcatca catcaaaact aaataattga tgttcttcac aaaaagaacg tgttatctcg
    20101 atcagttctt gattgattaa tgtatgcagg acaagtgctt tttcttctaa tgcatcttgc
    20161 aatgcctgcc ttaatgtttt ttcatctgtc acgaacgttc tgcggaatag gttgaactca
    20221 acggtaggat actgagccat agtagcttgc gctagttttg tcgcagtttc tccagcagag
    20281 tcggagatga caaaaaaagt aacgatttct gtagaatcgg aagtcatgga taaaacctca
    20341 cttgcatttt ttttatgttt attataccat actctagaat gcgtacttcg taatcatttt
    20401 gatttggagg gataagtcat gaaaaaacag acattgatcg aacaatcatt agaaacattg
    20461 aaaaataacg gttttaaata tactaaaaaa agagaagcat tgttaactta tttagtgaag
    20521 cgtaaccgct acgtatctgc taaagaagtt tttgactata tgaatcagga attcaaaggg
    20581 gtaagttatg atacgattta ccggaatctc catgattttg cagagatcga tttactggaa
    20641 gaaaccgatt taaatggaga aatgaagttt cgttttcatt gctgtcaggg gaaaatcggc
    20701 catcaccatc attttatctg tacagtgtgc ggaacaacga aagaaatcca tatgtgtccg
    20761 atgaattatt tcgaagaaca gctaggtgga tgcacgatcg aagggcatag attcgagatt
    20821 ttcggaagat gtgaaaattg tcaataagga tttaaataaa ataacatttg ataattttaa
    20881 aaaaaagcaa gatttccttg acggtcaaaa cagcattaga tataatattt acaggacagt
    20941 cttgtttttt gagatatatt tcaataacaa ttacggttac tttttaagct cggagggagg
    21001 gaattaacat gtcaaaaaca gtcgttcgca aaaacgaatc acttgacgat gctcttcgtc
    21061 gcttcaaacg ttccgtgtca aaagcgggta ctttacaaga atctcgtaaa cgtgaattct
    21121 acgaaaaacc aagtgtaaga cgcaagaaaa aatctgaagc agctagaaaa cgcaaaaaat
    21181 tctagttctg tgatgaattg gagttggtag tgtgtcacta ctaagtagat taaacgatga
    21241 catgaaagca gcgatgaaag cgaaagataa ggaatcttta caagtcatcc gaatgatcaa
    21301 gtcatctata caaaacgagc agattaaaga aggtcacgac ttgacagaag aagaagaact
    21361 aacggtgttg tctcgtgaaa tgaaacagcg acgtgattct ttgcatgagt ttgaagaagc
    21421 aggacgtgac gatttagctg aaaaagtaaa aagtgaaatt gtaatagtcg aaaaatatat
    21481 gccggaacaa ctttccgacg aagaaattcg acaacttgtt caagaagcaa tcactcaaac
    21541 tggtgcttca tcaatgaaag aatttggcaa agttatgggt gcaattatgc ctaaagtcaa
    21601 aggaaaagca gatggaaacc aagtgaatgc gattgtgaaa gaactattac aatcttaatt
    21661 ttatcattta aactgcggac agtgattatc cgcagttttt tgtgttcgta aaaaaagaac
    21721 taaaaaacag ctagaagaaa gaatcttatt cttt
//
LOCUS       DAFELK010000049        21592 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFELK010000049
VERSION     DAFELK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.050"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            144..542
                     /locus_tag="LP433_002108"
     CDS             144..542
                     /locus_tag="LP433_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL2006248.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="LP433_002109"
     CDS             526..1221
                     /locus_tag="LP433_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBL2006249.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1815..2702)
                     /locus_tag="LP433_002110"
     CDS             complement(1815..2702)
                     /locus_tag="LP433_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL2006250.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKELYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2887..3726
                     /locus_tag="LP433_002111"
     CDS             2887..3726
                     /locus_tag="LP433_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL2006251.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3922..4896
                     /gene="sgrA"
                     /locus_tag="LP433_002112"
     CDS             3922..4896
                     /gene="sgrA"
                     /locus_tag="LP433_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBL2006252.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5194..5550
                     /locus_tag="LP433_002113"
     CDS             5194..5550
                     /locus_tag="LP433_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006253.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5553..6710
                     /locus_tag="LP433_002114"
     CDS             5553..6710
                     /locus_tag="LP433_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2006254.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6736..7176)
                     /locus_tag="LP433_002115"
     CDS             complement(6736..7176)
                     /locus_tag="LP433_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL2006255.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7336..7842
                     /locus_tag="LP433_002116"
     CDS             7336..7842
                     /locus_tag="LP433_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2006256.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8010..9923
                     /locus_tag="LP433_002117"
     CDS             8010..9923
                     /locus_tag="LP433_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL2006257.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTKQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9928..10929
                     /locus_tag="LP433_002118"
     CDS             9928..10929
                     /locus_tag="LP433_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2006258.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11131..11337)
                     /locus_tag="LP433_002119"
     CDS             complement(11131..11337)
                     /locus_tag="LP433_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBL2006259.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11982..12830)
                     /locus_tag="LP433_002120"
     CDS             complement(11982..12830)
                     /locus_tag="LP433_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2006260.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12829..13896
                     /gene="gnd"
                     /locus_tag="LP433_002121"
     CDS             12829..13896
                     /gene="gnd"
                     /locus_tag="LP433_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBL2006261.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13898..14899
                     /locus_tag="LP433_002122"
     CDS             13898..14899
                     /locus_tag="LP433_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBL2006262.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14896..15180
                     /locus_tag="LP433_002123"
     CDS             14896..15180
                     /locus_tag="LP433_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBL2006263.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15213..16010
                     /locus_tag="LP433_002124"
     CDS             15213..16010
                     /locus_tag="LP433_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2006264.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16024..16857
                     /locus_tag="LP433_002125"
     CDS             16024..16857
                     /locus_tag="LP433_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2006265.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16875..17732
                     /locus_tag="LP433_002126"
     CDS             16875..17732
                     /locus_tag="LP433_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2006266.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17754..18263
                     /locus_tag="LP433_002127"
     CDS             17754..18263
                     /locus_tag="LP433_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2006267.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18300..18701
                     /locus_tag="LP433_002128"
     CDS             18300..18701
                     /locus_tag="LP433_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006268.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18813..19166
                     /locus_tag="LP433_002129"
     CDS             18813..19166
                     /locus_tag="LP433_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006269.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19200..19643
                     /locus_tag="LP433_002130"
     CDS             19200..19643
                     /locus_tag="LP433_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2006270.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19660..20745
                     /gene="uxuA"
                     /locus_tag="LP433_002131"
     CDS             19660..20745
                     /gene="uxuA"
                     /locus_tag="LP433_002131"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL2006271.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20738..21451
                     /locus_tag="LP433_002132"
     CDS             20738..21451
                     /locus_tag="LP433_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2006272.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7442 a         3314 c         4493 g         6343 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 taactattac ttatttctca tttaaacgat gtattcccta acctctaata catccttgta
     1381 actctgaagt tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata
     1441 aaaatatctt tcgtgtttct ctagtataac agaataagaa gaacaagtcc agaagggata
     1501 tttttagtct tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg
     1561 aagcgatacg gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg
     1621 attcatgtga tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc
     1681 agtgatttgt tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt
     1741 gcctcaaaaa taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat
     1801 tgggtcaaat ttgtttattt gaatatattt tttacataag gatctttaat agttacattg
     1861 tcttttttca tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct
     1921 tcggtagcaa ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt
     1981 ttttttacca tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga
     2041 atgatatcag aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga
     2101 atctctggat tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt
     2161 tttccataag cttgaacaag cttggagaaa ttttctcctt catttgcttc tttttttgct
     2221 ttatctgctt cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagagt
     2281 tctttccaag cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat
     2341 tggaaagcca gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct
     2401 tttaattgtt ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt
     2461 acttcctttg aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt
     2521 ttttttaata gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact
     2581 gtaagtgttc cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat
     2641 agtaaaattg cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc
     2701 atcctttcct tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg
     2761 taaggttgct gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat
     2821 ttacatagtt ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga
     2881 tgaaagatga tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt
     2941 gttttaggaa ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg
     3001 attggagcaa ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt
     3061 gctagtaagg tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac
     3121 tgggggtatt tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt
     3181 ccattatatt tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg
     3241 ataacgagtt ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc
     3301 ttttttcagc atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca
     3361 ttatttgctc ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc
     3421 tttttagcag gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct
     3481 attggtgctc atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc
     3541 ggaacgcaag aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact
     3601 gggggaaact ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt
     3661 gttggtttgt tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat
     3721 caataaaaga tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga
     3781 ttaaacgaaa aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca
     3841 actgactgtc gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta
     3901 attatatgga gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg
     3961 ctgagtataa ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag
     4021 aatctttcat ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt
     4081 actattccag tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca
     4141 tatggttggg atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac
     4201 gtacaatgga ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat
     4261 gagatcaaga gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc
     4321 acggagaatt tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc
     4381 acaagtagtg aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc
     4441 agtgaaagta gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa
     4501 agtagcacag gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc
     4561 acaggaagca tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga
     4621 aaagtaaata atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat
     4681 gcagggagca acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat
     4741 catcaagaaa aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt
     4801 agaaccttga acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca
     4861 agctattttc gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa
     4921 ttgaataaaa cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc
     4981 gaagttgtag ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata
     5041 acaggaacac aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta
     5101 gtatctctga aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata
     5161 agtctaaata atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat
     5221 gaaaggcaag tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg
     5281 gtgaaggata tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa
     5341 caagcagaat cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac
     5401 aagatgataa aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt
     5461 ttagagggaa cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc
     5521 ttagaaaatc ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag
     5581 aacttaatac tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga
     5641 tagaaggaga agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg
     5701 acgaaaatca ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat
     5761 ttgcgaaaca tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa
     5821 gaatttcgtt gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga
     5881 acaaatttgt gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt
     5941 tttttgaagc aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt
     6001 attttatgtt tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata
     6061 aagtacaaga aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact
     6121 tcaagatttg ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc
     6181 atttgtattc aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag
     6241 aagacagaga ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta
     6301 gtggggtagc tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga
     6361 tttttcaata ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat
     6421 tctatattca atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat
     6481 ctatgactga acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca
     6541 ttagcgatta tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact
     6601 ggaatggaca acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca
     6661 ggaatgagaa aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga
     6721 ttgtttatgc caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg
     6781 accagaaagc aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct
     6841 gattttatct tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt
     6901 tttcaataaa gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc
     6961 tattctgtga acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc
     7021 gttgtttgtc aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa
     7081 gttctgttcg ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga
     7141 cgagcagcca gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt
     7201 tatgaaataa taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa
     7261 aatgttgtca cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag
     7321 aaagaaggca caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa
     7381 ggggtatgtt ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat
     7441 aaaagaatca aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat
     7501 gctcaattag tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag
     7561 cacagttatt ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt
     7621 ttattaactg aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt
     7681 atagatacga ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga
     7741 gcaacgacaa cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag
     7801 aaaatttggg ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa
     7861 aaaagcagaa tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat
     7921 cctgttctat ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac
     7981 atataattct cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa
     8041 agggagcgtt ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg
     8101 gagagagcat ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg
     8161 ctggaaatga aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg
     8221 agacatctgt tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag
     8281 aagaagcaac agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca
     8341 aagagaatgg gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat
     8401 atttgaatta cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca
     8461 agtcaaaatt aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata
     8521 aagagattat caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa
     8581 acagtgtgtt gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca
     8641 caggcttcta tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca
     8701 aaatgatgga tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc
     8761 atggcggatt tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt
     8821 ataaggccgg gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg
     8881 attatgtgac ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag
     8941 ttcgagagcg gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga
     9001 tgatgtctgt attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg
     9061 gatttgcatc aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac
     9121 taccggatgc cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat
     9181 ttatgggcct tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg
     9241 ctctacctac gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag
     9301 atgatgtagt acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag
     9361 atcttttatt agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct
     9421 acacgaaaca tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt
     9481 atgtggatga aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag
     9541 cttatggaga aaattatatg acaaagcaaa agacattcga aggatacgaa ttagcaaatg
     9601 ttgaaggacc gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca
     9661 aaaaaatccc agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg
     9721 gaaagaatga acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag
     9781 tgaaagtaca aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga
     9841 aacattcgct tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga
     9901 tttggcgaag aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta
     9961 ccagttatca tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag
    10021 ccgattagct tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc
    10081 cgaccagatg atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat
    10141 ccttcaaagt acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa
    10201 ttaccgattc ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt
    10261 cgtgattatt tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat
    10321 gaacgatcac cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa
    10381 gcagctaaaa aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat
    10441 tcggcaggtg cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa
    10501 aaagctgatc atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg
    10561 tctggtctgt tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt
    10621 tatgaaaaat gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc
    10681 aaaagtttag ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat
    10741 ggaaatacaa atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg
    10801 ggggtgaaag tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat
    10861 cagtttgatt tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc
    10921 aaggagtaaa gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca
    10981 aggagcaatt tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag
    11041 gagttagaga tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg
    11101 tcacgatctc ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa
    11161 agcaacaaat ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa
    11221 gaatgctggt tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat
    11281 agcaaataaa atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag
    11341 cagcacctcc ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag
    11401 tttgttagga tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat
    11461 aagcaattaa tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca
    11521 ataatagaaa atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc
    11581 caaaaattcg atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa
    11641 taaaattaca aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt
    11701 aattcaccaa aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaga
    11761 aaagataaat tttttactac tgtatactaa ctttgttatc gcatctaaca agtaactcga
    11821 ataataccaa tacaaccttc tccaaagatg cgatgacata cgttctaacc caccgactat
    11881 tgatgttctg taccaccctt gcagaaccaa aaaagccact accaaatatt tggtagtggc
    11941 tttttttgtt ttatggattt ttcgcttttt ctgttatggt gctattcttt gatttcagaa
    12001 atagtatgtc gaactttagc gatagaacga cgtgattctt tttcgttgta aaacatcaaa
    12061 atcacatata gagagtccaa aatgcttagt tgagaaatac gggaagctaa agcttcagat
    12121 cggaattctg tttcttcaga aatagaaata aaaacgacat cgccaagttt agcaagggaa
    12181 gaattagctt ggctagtaat aacgattgtt tttgctccag tttttcttac ggtttcagca
    12241 atatggattg tttcttttga ttgccctgtg tgagaaatca aaacagcaca gtctttttcc
    12301 gtcaataaag aagcttccat caattgaata tggtaatccg tgctgtgaga agttgcgata
    12361 ggggaacgca aaaatttatg ataagcgtca gttgctacaa tctctgaacc gccaacaccg
    12421 aaaaaataga cacgtttaga ttcattgata atagtagccg ctttttttag atccttttgt
    12481 tgtaacaact tttttgtgtc atttaaagtt gaaatactag actcgaacac cttttgcgcc
    12541 atagtgagct cagtatctgt tttctgaata ttttcgtgga tagaaatagc agatagatca
    12601 ttttcttgga tcaacatggc cattttaaaa tctttaaatc cattataacc aagttttttt
    12661 gtaaattgaa aaaaagtaga gtcagcaatg cccagttcac ttgctaaatt gctaatagga
    12721 ctatgactta ctttgcttgg attttctaaa atataatcgg cgatagcctg ttcttttggg
    12781 ctgaagtcgt tgtacattgt tttgatttgt agtcttatgg agacgctcat gagaattcct
    12841 cattttcata ataagattat cattttttcc gttctcatta atgttaaaga tacaaggaga
    12901 gtaggaaaaa atcaaacaaa aaatattttt gtaaaatcta tttacaaaaa aatttttttg
    12961 tataatgagg gtataagaaa tggaggcgct atcatggaaa ttggtgtaat tggtttggga
    13021 aaaatgggat tgaatttagc tttaaactta aaagagcacc atcacaaagt acaaggactc
    13081 gacatttcaa gtacagctgt tagtcaggca agagaaaatg acattcctgc ttatcaagag
    13141 atctctgaat ttctagctac ttttgagcag aaaaaaatca tctggttaat gcttcctgct
    13201 ggagagataa ccgaaaacat gttaagaaaa ctttttccaa aactcggacc aggagacatt
    13261 attattgaag gcggaaactc ttattataaa gattcaatcc gtcgagcaga agagtttcag
    13321 aaaaatgaaa tcggttactt ggattgtggg acttctggag gaatcgaagg agcacgacat
    13381 caagcctgct taatgattgg aggagataaa gaaacttttc tatccgtgga acaattattc
    13441 aaagatgtag caattgaaag aggatatctg tatgctggtg catccggaag cggacacttc
    13501 ttgaaaatga tccataatgg aatcgaatat ggaatgatgc aagcaatcgg tgaaggattc
    13561 caacttgtac aaaaaagtga gtatgctttt gacttggaac aagtcgcacg tgtttggaat
    13621 catggttcgg tgattcgcgg ctggctgatg gaaatcatgg aagatcagtt aaacgaacat
    13681 cccaatttaa gtaattatcg gggaatcgtt tctgcatcag gtgaagcaaa atggacggtt
    13741 gaaacagcgc tagaaatggc tgttccagtt ccagtaattg caactagttt gttcatgagg
    13801 aatctttcac aggaagaaga tagtttttca gcaaaagtag tttcagcact aagaaatggg
    13861 tttggcggac atgaaatagt tgaaaagggt gagtaaaatg ccagattatc atatagcaat
    13921 cgttaattcc agcagtttcg gaagagtctt tccacaccac ttggaaagat taaagtcagt
    13981 tggagacgtt catttcttta ctgttgatca agagattcca ggaaaagaac tagcggagtt
    14041 acttaaagga ttcaatatca ttattgcaag tgttacgcca ttttttcgac gagatttttt
    14101 tgaaaacaaa gatgaactgc tattgatttc ccgacatggt attggttaca acaatattga
    14161 tttaaaagca gcaaaagaac accagacaat cgtatctatc atacctgctt tagttgaacg
    14221 aaatgctgta gcagaaaata atataactaa tttgttgtcc atgcttcgac gcacgacaca
    14281 agcacaagca agagtcaagg acgatcgatg ggaagatcgg gcggagttcg tcggtaggac
    14341 gctgtttaac aaaacagttg gtgtgattgg tgcaggaaat accggaagcg gagtaatcga
    14401 aattttgcgt aacggttttc gctgtgatgt tctagcttat gatccttaca aatcagattt
    14461 atacatcgaa agctttggtg caaaaaaagt agaacttcaa gaattactgg aacaatcaga
    14521 tatcatttgt ttatgtgcga atttgacaga agagaactat cacatgattt ctgataaaga
    14581 agtcgatcag atgaaagaaa atgtttatct atctaatagt gcaagaggcg ctctagttga
    14641 tgaagaagcg atgattaatg gtctgaaaag cggaaagatc gcaggatatg ccacagatgt
    14701 tttagaagaa gaaccgggac gtcaagatca tccgtattta gcgtttgaac aagtagtgat
    14761 tacgccacat atatcggcct acacaaggga atgtttagaa gcaatgggtg aaaaatgtgt
    14821 cagagatgtc gaacagatca gtcagcacct tcttcctgaa cgttctgtcc agacaaagag
    14881 caactatata aaaggatgat gaagaaaatg gtgaacggtt taaaagtgaa aacaggccct
    14941 caattttatt tatatgaaga aggtggtatt tcaaaagttt ctgatctctt gaaatcatac
    15001 ggcgcgaaaa gagtactggt cacccacgga acggtatcat gggaaaaggc gctacctaaa
    15061 ttagtatttt tgaatgacga aacgattcaa tttttttatc atcgttattc tggagaatgt
    15121 agttatgctg aagccagacg aatagctaca atcatcaaaa aaatgaaatc gatttcgtag
    15181 ttggcgttgg cggaggaaaa ctgaccgatc tagtgggtta tagtgccaat cttgcaagaa
    15241 tcgatttcgg agtcatccct actttagcta gtaattgtgc tccatggaca cctcttgctg
    15301 tcatgtataa ggagaatgga caagcagaag ggaaaacaga acacttttac agacaagctg
    15361 ctttttttat aacagatccc caattagtga ttgattcccc tgttccatat ttcattgccg
    15421 ggttagcaga tacactagca aaatggtatg aatctgagct catcttagaa caagattttt
    15481 tgcaagatga atcatttttg aagctagcac aagatactgc gaagatctgc aaagaagaga
    15541 ttttgaatca ttctgctaaa gcaatccaag atatggcaca aagaaaactg acatcggagt
    15601 tcaaacagct ttcagagatt atctttgctg ttgctggttt agttggagga ttaggagata
    15661 aatacgcaag aaatgtggca gcacatgcta tgcatgacgc tatcagtaaa tatattccgg
    15721 aaagccatcg ttttctacat ggagaaaaag tagcgtatgg gattttctat caactggcac
    15781 tagaaggtcg ctgggaaaaa atagacgagt tatatccttt gtatcgggaa ttagaactgc
    15841 cggtttctct agaacaaatg ggattatttc cgaaagataa acagataata gataaaatgg
    15901 ctgaatttat tgattcgaaa gagaaagtgc atttgattcc tatagaggta acacagaaat
    15961 cactgataca gtcaatgatg gaactggaag gttatatcag aaagatctga aggaggagga
    16021 cacatggaaa cattaagtgt agtacaaagt ttgttgattg ctttatgggt agccgcggtt
    16081 atgtcccgct ggttaggtgg aggagccacg ttgaccttac gtttttctcc tttgatgact
    16141 ggattagtcg tcgggttgat catgggggaa gttgcacaag cgatgattgt tacagccgct
    16201 ttgcaaatga tttatatggg ggttttttct ccaggaggat caatgccagc tgaaccatct
    16261 attgcagcag ctatcgcagt accagtcgca ttattagggg atctgtcgcc agaagcagcg
    16321 attgccgttg cggtgccagt cggattgctc ggaagttact tgtatcagtt tcgttttttc
    16381 atcaatactt ttttaggtaa atatacagac aaagctgtag aagatttgaa tacaaaagct
    16441 atggcccgat caattattct ttatccaacg gttgcctcat ttttattatt cgttccgctt
    16501 gttttcattg ctttatattt aggggcgcca ttgatcgctg atgtaatcaa agctttagag
    16561 ggaacagtcg ttatccacat tcttgaagta gtaggtggag ggttagcggc aatcggtatc
    16621 gcgacaactg tatacgttat cggtcgaaaa gattatctgg tctttttctt ccttgcttat
    16681 tttatgagtg ttgttttgaa atctttagat attacgatgg ttacttatgc catttttggg
    16741 attattatcg ctttgatctt tgtccagtcg caaaaaggga aacaagtaca gcctgccaca
    16801 agcaataaca attcagcatc ttttgatgac gaagatgact atgatgacgg attttaattt
    16861 aggaggaatg ggaaatggct gaaataatgg ataatcaaac aggtgctcct gaagaaatca
    16921 cgaaaaaaga tgtaacaaaa gcctatctga gatggcattt tgcaaacgaa attcctcact
    16981 cttttgaacg ttacttggcg ccatcactac tatacggaat gatgccaatc ttgaaaaaac
    17041 tttataaaga tgaagactct ttaaaagcag catataaacg gcagttactg ttcttcaaca
    17101 ctcaattaag ctggggtggc ggtgtgatta ctggcctaat gtcttctatg gaacagcaaa
    17161 gagcagaaga agagtatgaa gaaaaagaga tcttgatgca ggatgacttg atgtataaca
    17221 cgaaagcggg attgatgggg gcactagcag gaatcggaga tgcaatcgat tcaggaaccg
    17281 tccaatatat ttttatcgca atcgcggtac cttgggcaca acagggaagt cctttaggcg
    17341 cactttttcc ttttatctgc tttgggttgt atcaggtttt actaggggta tttttcgcaa
    17401 gacaagcttt cactatgggc cgtaatgcta caggcctaaa gcaaaacact ggtgttcaga
    17461 cagcgattga aatgctatca gttttagggt tgtttatgat gggggtgctt gcgggaaact
    17521 atgtaaaagt agaatcttca ttgaaatttg cgatatccgg acgtgagttt gttatccagg
    17581 aaattcttga tcaaatcgtg ccagggatat tacctttagc tgtcgtaatg ggtgtgtact
    17641 tgttctatac gaaaaaagga ttgaaagtca cacaagcatt attatggctg actggaatat
    17701 taattgtgct agcaggaatc ggtattttat aaaaagaagg gaacgtgaat aagatgggtg
    17761 tagtcaattt agcgcgtgtg gatgagcgtt tgatccatgg gcaagtaatg gtaacgttat
    17821 ctcaaaaaag tggagtgaat tccatttttg ttgtagacga agttgtagca aaagataaat
    17881 ttatgagaga tctttacaaa aatgcaggaa gccgtacagg acaaaaaaca attgtcatta
    17941 caccagagaa agctaaattc tattgggatg aatatcaatt taaagaatac aattgtattt
    18001 tgatcgcaaa aacagtccaa acgatttacg acttagtaaa acacggaatc cccatggaag
    18061 aattgaatat tggagggatt gctcaaaaaa atcctgatac agatctttta gtgacgaaat
    18121 ctgtttattt aaataaatca gatgctgaaa aattgaaaga aatgaatgaa caatatggcg
    18181 taaagaatat ttattttcaa gccactccat ctgcacctaa aacaggatta aaagatgtat
    18241 tgaacaagtt tgatttgtca taaacaaatg cttagaaaaa agataaagag ggcgaaaaaa
    18301 tgaagaagaa cgagctgttt cgtgattggg aatttcgtta tcgctatatt taccgtaagc
    18361 gccgtacaaa aaagagtaaa cagcgttttc tttcagcatt agtatcagat atttacagta
    18421 tgagaacaga tgtgacagtc attgcttacg atacgctagc ctaccgatca aaaaatattt
    18481 atgttggaga tatcgaaaaa gcagagaaag ttatctgtac ttattacgat acacccgttc
    18541 atgcattagg aagttatttc atgtttgatt ggaaagacca aaggaaaaaa acaatctact
    18601 ctatattatt gtccttcatt ttgttgttca gtttaggttg gtggggaatg atgatatata
    18661 acaaaaatcc tcatcacgta ttcgatctgc tatccgtata aacaggtatc actgtactag
    18721 catttgggag ctactttttc ttattgggaa aagcagctcg cggatggcct agcagacaaa
    18781 cttttattcg aaatacttca tccatattaa cgatgctaga aatgatccgt acgattgatg
    18841 atccgagtgt agcgtatgcg tttgttgatg aaggctgtta tggagaaaag ggcttagaca
    18901 gcgtgagatc gggtatgaaa aaagaggcta ttctttttta tctagactct gttggggcag
    18961 atacaccgct acagttttcg ggaaattatt tttcaaataa agaacagtgg ctgaaacaag
    19021 ttgataagtt gaaagaaaaa aacgtcaatt atatttttag tgcaagaaaa aagcaagcgc
    19081 agttcttcta tttgaccaaa acagatttac gagggaaaac atttaattgg caaaatgcca
    19141 atcagattat tgctcttttt cgataagtaa aaagtgcaaa acaaggagtg agaagactaa
    19201 tgttggaaat catgatcgtt acacatggta agttgagcga aggactgaaa gatgcggcgg
    19261 aagtaattgt cgggacatcg agccatattg aaacaatgtg cttagagtct ggggaggaca
    19321 tccaaacatt cggagagaag gtcaaagaaa aattaactat gatcaacaca gcagaaccca
    19381 tgctagtatt tgttgatcta attagcgcaa gtccgtacaa tcaagcgctc ttggcagtca
    19441 atgaactgac tgaagaaaag aaagcagcca cttatgtcat agggggcgtg aatctgccaa
    19501 tgttgttaga agcaatcaat catcagatgc ttcacacacc gatagaagaa gcggtggaac
    19561 aaattgtcaa acaaggaaaa gataatttaa ctgtttggca tgcttcagcg gaagaaaaaa
    19621 aattagatga ggacgatttt tagaaggaag gctgaaaaga tgaagtgggg atttagatgg
    19681 tatggtgaaa aaggggattc gatcccatta aaatatgttc gccaaatacc gggaataaat
    19741 gggataattg gaactttgct gactaaaatg cctggagatg tttgggagat ttcagaaatt
    19801 gaggagttga aagcatctgt tgagagccaa ggactggaac tgcttggaat tgaaagtgta
    19861 gcgatccacg atgcaatcaa ggcagggaca gatgaacgag attactatat tgataactat
    19921 atacgaacaa tcaaaaactt gtctcgatgt ggggttcgat tgatttgtta tagcttcaaa
    19981 ccaatttttg gatgggcgaa aactgatttg tttaatgaaa acaacgatgg aagctattct
    20041 cttttatacg atcagaaaat cgtcgatcag atggagccag gagaaatgta tcaattgata
    20101 cacagccagt caaagggatt caaattgccg ggttgggaag aagaacggtt gaaaaaattc
    20161 gctcagctgg aaaaactgta tgaaggaatg accgaagaag aattatttga aaatctgact
    20221 tattttttag aaaaagtgat tccagtgtgc gaaaaagcag atgtaaaaat ggctatccat
    20281 ccagatgatc cgccatggga actttttggt tttcctagag tgacgaaaaa tcttggcgac
    20341 ttgaagaaaa ttctaaatgc agtagattct ccatataatg gactaacgct gtgcacagga
    20401 tctttagggg caaatccgga aaacgattta gttgaaatca tccatgaggt aggttcgcgc
    20461 atccattttg tccacttcag aaacgtggag tttttaggag aaagaaagtt caaagaaacg
    20521 gcacatccct ctacagaagg ctcccttgat atgtatcata ttatgaaagc gttggtgcaa
    20581 gaagggttcg acggtcctat acgccctgat catggtagaa ccgtgtgggg tgaagtggct
    20641 atgcctggat atggcctgta tgatcgtgca atgggactca cttacatgca aggtctatat
    20701 gaggcgataa gtaaggaaaa accactggga gagcattatg aataaaatca agctcttcat
    20761 ctttgatatg gatggccttt tattagaaac tggacgttta gcttatcgtg cttatgtaaa
    20821 atcagcacaa aagtatgatt atgaaatgcg taaggaagtc tattatttac taactggcca
    20881 aacagaaatg gcgataagag aacaaatggg cattttgtac ggagaagatg ttccatatat
    20941 caaatggcga gaagcaatca atcaatataa agaaaaaatc gtgaaagaag ataagagagt
    21001 atatacgaaa aaaggagcag aagaaatttt atcttttgca aaagaaagag gaatccatac
    21061 aatcgtggct tcgtctaata cacgggtaaa agtagaaatg tatttaaaaa tggaaaatct
    21121 atatgccttg tttgatcaaa tcatttcagg ggatgatgta aaaaaaggaa agccggaacc
    21181 agagatcttt ttgaaagctt gttcaaaaat gaatattcct ccaagtgaag cacttgtatt
    21241 tgaagactcg attgcaggga tcgaagcagc aaggcgagcg ggcattttgt cttttctcat
    21301 caaagatcat ttgatagggt tgcccgatca taatgggaag cataagttga aagtagatgt
    21361 aagtttatat gaatccaata aagcagacta tgaattttat gacctgcatc aagcaaaacg
    21421 atttttagaa agtaaagggt tgtatctcta ataaagagga ctattttcta gtcctcttta
    21481 tttattgtcc tgcacgactg agggaacaga tgaaaaagaa gtaatttttt attttgaagt
    21541 atctacctta tttgtagtga acaatttaga acaaacacaa aacgcatcta ct
//
LOCUS       DAFELK010000050        20772 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFELK010000050
VERSION     DAFELK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.052"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..303
                     /locus_tag="LP433_002133"
     CDS             <1..303
                     /locus_tag="LP433_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2006273.1"
                     /translation="LGVKGQNLLADDSFWQIEAFYLAQCAYNTTLMLSPDRIIFGGGV
                     MKQEHMKKKVQDKFVELINGYVEIPPIASYIVTPELGDSAGIIGGLALARKAIRNK"
     gene            complement(1794..2459)
                     /locus_tag="LP433_002134"
     CDS             complement(1794..2459)
                     /locus_tag="LP433_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2006274.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2585..4522
                     /locus_tag="LP433_002135"
                     /pseudo
     CDS             2585..4522
                     /locus_tag="LP433_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
     gene            complement(4725..6044)
                     /locus_tag="LP433_002136"
     CDS             complement(4725..6044)
                     /locus_tag="LP433_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBL2006275.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            6308..6946
                     /locus_tag="LP433_002137"
     CDS             6308..6946
                     /locus_tag="LP433_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006276.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            6974..7402
                     /locus_tag="LP433_002138"
     CDS             6974..7402
                     /locus_tag="LP433_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006277.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            7859..8770
                     /locus_tag="LP433_002139"
     CDS             7859..8770
                     /locus_tag="LP433_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL2006278.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            8987..9424
                     /locus_tag="LP433_002140"
     CDS             8987..9424
                     /locus_tag="LP433_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006279.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            9519..10403
                     /locus_tag="LP433_002141"
     CDS             9519..10403
                     /locus_tag="LP433_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL2006280.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            10627..13767
                     /locus_tag="LP433_002142"
     CDS             10627..13767
                     /locus_tag="LP433_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006281.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEIT"
     gene            13814..14359
                     /locus_tag="LP433_002143"
     CDS             13814..14359
                     /locus_tag="LP433_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HBL2006282.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            14387..14842
                     /locus_tag="LP433_002144"
     CDS             14387..14842
                     /locus_tag="LP433_002144"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HBL2006283.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            14839..15597
                     /locus_tag="LP433_002145"
     CDS             14839..15597
                     /locus_tag="LP433_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL2006284.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(15683..16423)
                     /locus_tag="LP433_002146"
     CDS             complement(15683..16423)
                     /locus_tag="LP433_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2006285.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            16484..17737
                     /locus_tag="LP433_002147"
     CDS             16484..17737
                     /locus_tag="LP433_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL2006286.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            18022..18285
                     /locus_tag="LP433_002148"
     CDS             18022..18285
                     /locus_tag="LP433_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL2006287.1"
                     /translation="MEKQANPYDHKKMLTQQLRELEQDESIHRKAYNQVPPKVEYSLT
                     EEGKSLREILVALSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            18408..18734
                     /locus_tag="LP433_002149"
     CDS             18408..18734
                     /locus_tag="LP433_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL2006288.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            18802..19515
                     /locus_tag="LP433_002150"
     CDS             18802..19515
                     /locus_tag="LP433_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL2006289.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            19825..20676
                     /locus_tag="LP433_002151"
     CDS             19825..20676
                     /locus_tag="LP433_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2006290.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
BASE COUNT         7024 a         3381 c         4149 g         6218 t
ORIGIN      
        1 ttgggtgtaa aaggccagaa tttattggct gacgattcgt tttggcagat tgaagccttt
       61 taccttgccc aatgtgcata caatacaaca ctgatgcttt cgccagatag aattattttt
      121 ggcggtggtg taatgaaaca agaacacatg aagaaaaaag ttcaggataa atttgttgag
      181 cttataaatg gatatgttga aataccacca attgctagct acattgttac gcccgaatta
      241 ggtgatagtg ctggaataat cggcggattg gcattggcta gaaaggcgat aagaaataag
      301 taattttaat gaataaatgt ttcattggta ctcatgtcaa aagtatttaa ctgagtaatc
      361 aaatgatgtt tgataaagcg aaaatgaatt caaataaaaa aggatcgagc aaactggaac
      421 atttgtccga tcctttttca cattctattt atttcgttta ttcaaccaat cggtagagac
      481 atccattgcg ctcttgtcgc gtggctttga tccatataat tgaccattac gaaatcatgg
      541 atcatcgctt tgaatgcgaa cttgtgtcac atctactttt ttgaccagat tttgaccagt
      601 ctattttaca ttctaatgta cttatatgag ttaatttttt gagtaaatgg taagtttttc
      661 cttgtttgtt ttatcttaaa ctagtgtgta atttgaaaat ctatatggaa gggtctgtgg
      721 ggtaatactt aaataaaggc taggaacctg ataacatcaa ggttcctagc ctttttataa
      781 taaaatgaag cgaaaataat ttcttttaaa gagccgagat tatcagctat ataagagtga
      841 atttgatgca aaaaacagag ccgaaacagt cttggtgttc gtagctctgc ttatatgttt
      901 cgaatttaag acaaagagtt ggcaaaagat gttgataagg aagataagat aactgtgtta
      961 tataaactag gtaactaact gtaacaagct aattttaaga gattcttatt agaagacgtt
     1021 taggaatata actaagaaaa tgattataca ggtaattgtc atttcaataa tgttttctaa
     1081 ttttcgcgtc tttgttttaa gaaaaaggcc agaatcagtt ggaaaaaagt tcgtacgata
     1141 gtgaagaggg gcaaaatttc ctactaatat tcccactaac aagagataaa acggccaggt
     1201 tggtgtgatt cctctataaa aaaatgccca tgctaccgaa atcccataga ttaacaactg
     1261 aacaattttt acaatgaaaa aattgttctg ccattactca aagtctcttc ctccttgtat
     1321 cgtttatttg tttcatttta tcattatgat aggcgcttga acaatccatt ttgtatttta
     1381 ttgagtactc ttggataaac taccagcgat tatcatattt atttatgtta ctgtaagcca
     1441 tcatataaaa gtaaatgagc agatcataga aatataaaaa agaactaaaa ttgatctaaa
     1501 ttatgtgcag cttgactacg taccaatcta tattacttac tagattggtc gttaatctat
     1561 tcggatcgaa tgagcaaaat atttttgtga atgtccatcc ttgattatga ttccaaaaag
     1621 aatcattgga aggctgtggc gtaaatatta tactataagc cagaaatacc tatcattctg
     1681 aactttttta tttaggaact ttcatctcaa ggctttttca attaatttgt acccctgttt
     1741 tttggataag atcatgtgca ttgatttttt ctatctctac gttcatctcc tacttaatgc
     1801 ctatctggct cctgagggct tctttttaag gcgtcgtcat agtcttggct gaggatttct
     1861 tggtaatctg agggaatggc ttcccaagtg agcaggcgaa cgttcatgac gtgttttcct
     1921 ttgtgtttga ttacagcatg gtttttctct ttttctacct ctccagcgtg aaaagacagc
     1981 catgtaccat ggccaaagat atcattacat acccaacgtt cgatggaatt gtccacgtat
     2041 cctacaggga gtgtggtata gccgatttgt ggtttcaaaa aaggattgaa tcgatcgatc
     2101 gtttcatttt tgtattgata attgataaga aaaagataga ccaaacaaaa gacgagcaga
     2161 aagaaagata gtgtcttttt gagtgagaag ggttgttttg atgaataaga tttcttgtta
     2221 acaagaggtt catctggcaa tgttggttct attgattcgg tagctgattc aatagaagga
     2281 aaatcaatcg gcagacctaa agtatgatgt aaaagtgaca gcatttcaaa gtctggcatt
     2341 gtacgagaat tttcccaact agaaatcgtt ttatcggaaa caccaatttt ttcgcctaat
     2401 tctttttgcg taagcttaca atttctgcgg taagttcgta ttttttctcc ggtgttcatc
     2461 ttcttctcct ttcgattcta cagtatatag atttattcta catgacctat acacttgata
     2521 gatacgtttt tttgatgaaa aacggtatga ttttatcaaa gaatcattta agtaagggag
     2581 agtggtgata atcaaaaaaa agttcacagt tttactcaca atcatagtga ccggtatcat
     2641 gagtggtttt gccttggtta gtataaataa acaggtactc tatcggacaa atgaattttt
     2701 ccatcaaaca gatacttata ctccgattcg attgccacaa cattttattg ggcaagaaga
     2761 atatgagcag ctaatcatgg tatttgaaaa tgtctcatca gaaactgagc tttcttatat
     2821 gaaaaaaaca gtaaatgaat ccaatgaagt agatacatct tggaacttca agatacagcc
     2881 aaagcttgaa atgacattgt attatcaagg ggatgtcaaa tcttctcacg agaaggtacc
     2941 ctattctaat acctcctttc gcgtaacgtc cattgaagaa tcgatcaaaa taaaagattt
     3001 tgaaggtgaa tttttcttga tgacgagaga aaaagaagcc tatgaacggg tcatttcact
     3061 attcactgat cgattcaatc aagcatttca cactgattat gccactaata tttttgaaga
     3121 ctttgaaaat agctattcgt attcggttat ttcaaataca gacgtatata attatcgagt
     3181 gtatttaact attggattga ttcttttatt ccttttgtta tcatcctttt tcttattgat
     3241 gaataaagaa atcagtttat tgttgaataa tgacttttca ttacatcaag tattgtggtg
     3301 tttattgggg aaaaagaaaa tcattattac attcataatt gcaggaatca ttggtggttt
     3361 tatttttatg tattataagg agcaatttct ttatttgttc cagatgtacg ttttcttgtt
     3421 cagcggaata tatggtatct ctttgatttc tcttttatta gttgaaaaaa tcgcttcgtt
     3481 aagagaagcg ttcaactata tccaatacat tctttttaca tttggattgt tgttttctct
     3541 tcttttgacc gttgccaatg tcgaattagc aactatcgtt ttttcttctt cacagttagc
     3601 tgtttcccat gaaccaccaa aagaaatcgc tggtgaggac tatcatgtat tttatccagt
     3661 aaccatcggg aaaaaccacg tggattttat ttattccaat cgttttgcat cagcagcaga
     3721 tcaggaatta tatgaaactt tgaataaaaa cggaagtata ttagtcaatg tatcagatta
     3781 cttgaatgaa gaaaatgaac agtttggcag agggataaaa ataaatctga attatcttaa
     3841 gaaatttcct ttgattgatg tctctggaag gttgatccaa ataaccgaaa aagaaacgca
     3901 ccctgttata ttgatccctg aacgatatag acatacagat ttaaaaaatg acctggcgca
     3961 aataacagaa tattatcaag aaatcagtga aaaagaaccg aaatttctat ttataaaaaa
     4021 caatcaaccc atttatacat ttattccttc tatcccctgg atcgaacatt atccggttgt
     4081 tgaaatactg acattgaaaa acagtatgta tttggaaaga aatattctca gcggagaaat
     4141 ctatccaccg ttaaagatca agataggctc tttgtcgaaa gaaaggttat ttgagctgat
     4201 tgaagaaagt cagttacgtg ataacttgca gttatcattt ccgtatactc agactgaaga
     4261 gatagctgtc aaagtgttaa gcagatcatt tcattacttg atacagatat ttttactcac
     4321 tttcttttct ttcttcttgt tgagctatgt catgttatgc atatattttg tctacaattg
     4381 tcggaaaatc gctatctttc gttcaagtgg ttattcgctc tttgaaacgt ataaagattt
     4441 cttcatgatg aacctcatca aatggggaac gacaagtgta atcttccttt ttcttataga
     4501 aagagagcct aaatatcttt tcctgaataa ttcatagctt taattctttg gcacatttta
     4561 ttgaaatatg tatcactaat atccctatca actgattttg actaaaaagt tacttcaaac
     4621 attcactgtt caaaaatatt gaggaataaa ttttgggtgt aaggcatttt gagcatactt
     4681 ctccctggat aacttcccag taaaaaaatc gttagattgt tggattagat ccattgactg
     4741 gctcgcctca ggcgagcaaa gaccctgtag aattcattct gatacacatg ataactagat
     4801 aatttgagat agactcgtct acccgtttgg actaatttcc cagcaacttt cagaaacttc
     4861 aatcgaatag aatgaatggt cattcccttt tggacttctt caaagccaat cgttcttaag
     4921 aagttgacta agttgtaagc tatcaagctg agcatcattc ggacatgatt ctccaaaaag
     4981 cgaggactgt ctgttttgtc aaagtaaaag ccagctttcg cttctttaat gaagttctcc
     5041 attgtgccac gtttggcata gatagaaaag atggtatcag gagaaacatt ttctgataga
     5101 ttcgtcacga taaattcatg tcgaaagagt agttcgcccg cttcacgtgt tgagcgtata
     5161 cacacgcgac gactttgtga ccaggattgt gcttgataag tggtcgagaa gtactgaact
     5221 tctcgttctt cccacttttg attatcgcca taaagtactg atttctcagc tatttgacct
     5281 agtctacgat tattcttcag tcgaataaca taatgactct tttttgattc acacgaatca
     5341 tacacaccag gtgtagcgaa cccgctgtct ccacgaacca agatgtcagt gtttggtaga
     5401 gagtgattat agtgctctaa taaaggtgtg agaaactcct ttacgccttt tgatgtatat
     5461 tgatttcctg aacgtagttc agcttttaag aagtcaccag tcaatccgtc aaaagctacc
     5521 aatggatggt aaccataggt ttggtagtgt gtattataat tcgtttgttc ttggtgacca
     5581 aatgtatctg aatgggtcga atctaaatca atgattaatt ccgtatcatt acggatgagg
     5641 cgtgctttat cgataagttc ttggttcaaa gcttgaagtt catggatatt ctcctcagat
     5701 agtcgatcta aaaatcggga aagtgaagat tgagaagcga gttctttcct atctaaaaca
     5761 gctttaaaca caggatcttg tctcaggaga ttagctgcag aatcagctga gtaaccagca
     5821 attaattgca taatgaactg ctcaagtatg gataagttgt catgagtaaa atacgctcgt
     5881 tcgtcttcaa tgtgaatgtg ttgcttagcc agttcagaaa aaccaaagat gttcatcagc
     5941 tctttcacta ggacgagacc cgaatcactc gataattgac cacctgtatg agaaatagtg
     6001 atatttgaat tgaattttac ttggtttttg tgtaagctag tcatgaaaag aactcctttc
     6061 ttttggttgg tttagtcact ttaaccatag cagaaagggg ttcttttttc atcacttaac
     6121 gggtgaagat gaaaaagtaa ttgtaagctg ccgtgaggca gtttcacatg gttttaatta
     6181 aaagtatgaa ttattcaggc tttttaatat ttttttcttt agcttcattg attttattct
     6241 ttcagttgtt tttattttgt ctacagaaaa gaaaagtcag ttattgctga tgaatggagg
     6301 ttaacaattg gagccgttga tagtgataaa aggtgcgaaa aaaatcattc gaaacaaaac
     6361 gattcttcat ttggatcgtt tcactgcgga tgctggggat cttgtgactg ttgttggaga
     6421 aagtggagca ggtaaaagta cgttattgaa tatattagga ttgaatgatc agttcagttc
     6481 aggacaattc tatttgttcg atcaagagac gaaacaatta actgggagag agaagcgctt
     6541 gataaaaaga aataccatat cttttctttt tcaagatttt gggttgattg aatatgaaac
     6601 aatcgatttt aatttagata ttggattgaa gttttcgaat ttaaatgttt cagataagcg
     6661 aacagcaaag tatgaggcat tgaaaaaagt aaatataaac aagaagctaa gtacgcctat
     6721 ctacacatta tctggtggtg agaagcaaag aatcgcctgt gcgagagtct tattgaagaa
     6781 tagcaaaatc attttagccg atgaaccgac tgggtcattg gataaaagaa ataaggataa
     6841 agtagttgaa atcttatcgc aacaagcttc ccaaggtacg ttagttatcg tagtcacgca
     6901 tgatccatat ctgaccaaaa taggaaacaa gaagatcatg ctttaaaaat caaaaaggaa
     6961 aggatgtcgt tttatgaaaa aagcagttat tatttgtgca ctagggatag gttttgttgg
     7021 aggaaacgct atgtcatctg aagtggaagc aaattcagtt cacggtgaaa tctattacaa
     7081 atctttaaag ccaggagaga ttcattttga tgctaaaggt aatattatta agtcaaattt
     7141 accagtagac cgggaaattt ctagaacagc aattaatcat agctctggaa gatgggttta
     7201 ttatagtgat acaacttgta cgagaaaaac aggtcattct aaccactata gtcgtgtcta
     7261 taatcgtcac ggtgcaaaag cgaaagttgg aaactctatt cgatcagcaa atgcaacaaa
     7321 aggagtatgg gcctatgcaa gtgcgacagg aaatagaact gacacattct catgttggta
     7381 caatccaacc ggttggtatt aagtatccaa aagtttatat aaaatagaaa aaacatataa
     7441 tgaaacagcg ttaaaagtta tttttggtag ttttaatata ttcattttta gttgtataaa
     7501 aatatatcat aataaaaaca acaaaaaaat gtctggaaaa tcgaacataa aagtgtctga
     7561 tttgaatatc ccagcagcgg aagaagaaaa acaaaatcga taacatttgt tctaagaatt
     7621 agttacgtta aatacggaac gcaagataga cttgaaaaac ggtaacaaaa gaagtagtat
     7681 attaaggtgt gatgtgctac ttgacattta ttctgctgag cgaactttct ggattgtgta
     7741 gccttatatc tattcaggac gtatcgagca gattagtaaa ggtgttcttg atgattttca
     7801 tcttgaacac ctttgttttt agcaattcgc aaaaaacgaa aagtaggaga attgataaat
     7861 gaaaaaaaga tttttagcac ttgccatcgt actaggcact ggcttattgt caggctgtac
     7921 gaatgccggt gaaaaaacag ccgttagtta taaaggcggt acaatcagcg aacaagaagt
     7981 aatggatagc ttgaaaaaaa tgcaaggagc agattccgct gtgcaacagt tgatcgttta
     8041 tcaagtattt gaagataaat atggagatga cgtatcaacc aaagaaatcg attctcaata
     8101 tgatcaaaca aagaaacaat tgggtgattc atttgattca caattgaaat ctgcaggtta
     8161 cacagaacaa acattcaaag acagtatcaa acaaagtcta gcctttcaag aaggtctaaa
     8221 gaaacatatc aaattgaccg atgaagattt aaaaacggct tgggaatctt tccatccaga
     8281 agtggaagct caaattatcc aagtagcaag tgaagatgat gcaaaagatg tgaagaaagc
     8341 tgctgataag ggagacgatt tctctaaatt agccaaagac aagtcaactg atactacgac
     8401 aaaagaagat ggcggaaaag tgaaatttga ttccactact acaacggttc cggcagaagt
     8461 caaagaagca gcctttaagt tgaaagatgg tcaagtttct gatgtgatca cttctaccaa
     8521 tgcttcaact tatactacgg aatattatgt ggttaaaatg gtgaaaaacc aaaacaaagg
     8581 caacgacatg gataaataca aaaaagaatt gaaagaaatt gcaacagaca caaaattaag
     8641 tgacagtacc ttccagaata aagtaattgg cgaagtattg aaagacgcta atgtaaaaat
     8701 caaagacaaa gactttgaaa atgttttgag tacattcact tcagattcta gtacagcaag
     8761 tagtaaataa gcggtataaa taaaaaatat gaactattta aatcaataaa actgttcatc
     8821 taaatctttt tattagaact aaatcaacag tagtttaatt actacttgat ttagttcttt
     8881 ttattttaaa aatttttttt acttagaatc cagcgaccct agatattttt ctgtataatc
     8941 ttaaataaag aaaacaatat caaaaaatgc acgtagaagt agataaatgg agtggttttg
     9001 caaatttctt ttatttctag aagttattca cgtatacgga tttgtttttc tcacaaataa
     9061 aaaggcagga agtacaatgg atcatttgta tataaaatat attcatcaat tttccgtttt
     9121 ggtgttaggc acactaatta tagcggggat tgtcgcattt attattcaag gccgtgacat
     9181 attaacagta catcaagagt ttttcagtta tgcatttggt attcctctga tcgctataag
     9241 gtctgataac aaaaagtgga agaaacgcta ttacattctc ttgctatttt tgtgttttta
     9301 tctgccacct aagattttta ctttattagg tatacaatgc ctatcatttt cttttatttc
     9361 ctatatcatt gttttaattt tcctcagttt catagtatgg atgttttatc ttgtcaaaaa
     9421 ataaatgaat gtttcatgaa cagtacttca tcacagccta atttttttct ttatgctatc
     9481 gttatattaa agaaatcaat cagaagggaa agaaagtgat gaaaaaagtt ttattagtgg
     9541 taaaccccag ttcaggcggt gaacaagcaa aggaatttga gcaattagcg atagcaaaat
     9601 tggaatcggt gtttgatgaa gtggtcgtct tgcatacaaa aaaagcaggg gatgcaaaaa
     9661 actttactcg cgaagcggct acggaagggt atcatagtgt gtttgtcatg ggcggagatg
     9721 gaacagtcaa cgaaggaatc agtggaatcg ctgaacaaga acatcggcca aatttcggat
     9781 ttttcccatt gggtacggtg aatgacttgg ctcgagcatt agggataccg ctagaacctg
     9841 aggaagcgat caatcatttt tcgattgaat cagtcaagcc attggatatt ggaaaaataa
     9901 atgacgacta ttttatgaat gtcgtcgcaa ttggctctat ccctgaatca atcaatgatg
     9961 tagatgcgga gaagaagacg aaatttggaa aactagctta tttcatgtca ggaatcaaac
    10021 agttagcttc cacacaatcc tactcgtttc acgtagaagt tgatggaaag aaggaagaaa
    10081 ttgagagcag taccttgctg ataggactaa ctaactcagt cggcggtttt gaaacattac
    10141 ttccaaatgc aaaagtggat gatggtaagc tccatttggt ttatttaaaa gattcttctt
    10201 tgatcgatac gcttaaaaca ttgccagacc tattaaaagg agtagatgaa tctacgaaaa
    10261 atctagccta ccttacttgt gagcaattag ttgtgtcatt agctgatgag gaagaattga
    10321 cgacgaatgt tgatggagat gaaggggata aattacctgt gacaatcaaa gtattgccct
    10381 cacatttaca ggtttattgt taaaatggag gttgtgaccg aggagttggc gggagaacac
    10441 cgcttgttcg ggataaggga ctgtgacaag acttttgtca cagccttttt tttgtacaaa
    10501 aaagaaattt acacctaata gaaaaatttt tccataaaaa tacatatttt aaatatgaaa
    10561 gtacaattgg aaatagatta aaacgataaa ataaaattgt caaaacgtca gagaggatgg
    10621 tggagaatga atcaatgtgt aaaaaagctg attgcgtcga ttttgtttgt cttccctctc
    10681 ttgatggtga catccgtttt tgccgatgta gagaaaacaa acgaatcaac gcaatcagag
    10741 aatcaaagtt ttgacaagac tactttttca gaagaatcga ttacttctga aactacagaa
    10801 tctcaaagtg aggcttctac taataaaagg caagaagaaa ataagacaag tgagacctca
    10861 gaagtagctg aacaaacgtc tgatagcagt gaagcggcac tggcaagagc tgtttcagcg
    10921 gatgggtaca gcgaagctgc cacaacagaa gaactggcgc agcttctcgc agacgaatca
    10981 gtaactaaga tccgactgat tcagcctttg actttagaca gggaattaga gatcaaacga
    11041 gatatcgtta ttgattttgg tggattcgct cacaatttcg gcacacacca tatttatatc
    11101 aatgagatac ctcagtcgat cgagttccag aattttaaag gaacagctgc acatccaggt
    11161 ggattgacac caaatatcga tggaaatgcc attatcattg cttatatgac cgatttttgg
    11221 ggaagcagat atcattttac gggagaaata aaatttaccg ggacacttga tttgtatgat
    11281 gggtccaaat taggactgat ttacgctcct cgtgcaactg tcacattaga tggtgtttcc
    11341 ggtgtgttgg atgtccaacc agtgaaggaa ggactgaatg ccgctccggg taaagcctat
    11401 ttttgtagaa gctatcaatt gaatgtgatc aatggtagtc aactttatgg accgtatcta
    11461 gggaaattct acggttttct agattcagga gatgagactg gtagtggaaa aacagcgcca
    11521 ggaatccata tcttaagcgg ttcaaaggtc tctcttgatt atgatcgggc agatggcgtt
    11581 agcgatgaag gagaggcagt cgatacgcta cctggtaatg tcatgtttga agtcagtggt
    11641 tcgggaagcg aattttcggt aaatacaaag atcaatatta ccaatgacaa caatcgcgga
    11701 atcatccaaa tgagaggttc aggatcgaaa gtcactgtat cgaatggtgg gaaaatcacc
    11761 atcaatacag caactacggg cggatttcgc ttgcaaggag attctagtca aatccatgta
    11821 tcaagtggtg gacaaatctc ggtcaaaatg gctggagatg acgatcaacc cgggaacaat
    11881 gggatgcgtt ttgtaggaaa aggcctttct ttgatcgtag aaggagccgg atcagttatc
    11941 gacatcgata agcagagtgg gcgttccagc gcagttcgtt ttgagaatgg tacgcaaaag
    12001 ctgacagtaa ccaatggagg ctcattgagg gtaagaaata caggtgatgg caaatcttac
    12061 gtgaacagac tcaatcaagg aaatcaagcg atccaatttt atgacgcttc tggttttcta
    12121 gaaagtccag gttcagctga ttttacagtc actggagaaa aatcaaatat cgatatacgc
    12181 gcagattccg gagcaactgt agatacaact ggagatattg atttaaattt tacggcaggt
    12241 gaaaaaactt atttagtcat ggtcgggaaa acaggggaag ataagaccgg catcatcagt
    12301 ggggatgtgt tgaatgtgga cttagaatct cctacctatt ttgatttcca aaacaaacgg
    12361 attggaagcg agaccaatgg cataggcggc tgggtattcc aaggaaatgg agattcttct
    12421 ttaaagatcg cccattcaga aatcgcttta tggcgaaaaa caggcgcaac attcgataac
    12481 tttgaaaaag acccggatta tttttctgat atgacagact tatcgatcaa tgggaccgac
    12541 ttaggcaatt tcgtatcaag ccctagtgca ggtttaacaa atgaatttgc tcagacaggt
    12601 gccggaatga aaaattataa tcgaatcagt gccaataatc agctcccgat gattgaatcc
    12661 ttaagagtgc caacgaatgc agataaaaaa atctatgggc atgtcgttgt tcccgaaggt
    12721 gtcgaggcaa agccaagaga tgcttggaca ggcgaagtag aagtgacttt acgtattact
    12781 tacgcagata cgacgaaatc atctgtagaa attactgctc tcacgcaagg acaaacagat
    12841 gaaaatgaag gggcaggata taacccatgg ggagaaggcg aacaaggcgg cttgttcgaa
    12901 gttcaagtac ccaatgatga gagattaaaa acggaggatc aagtgcaagt tgttgctgct
    12961 aaaaaagtaa gaggtggcca agaagtgaca gaactggact ctgccaaaac gacagtcgat
    13021 gtgattcctc ctgaacctgc taatttaagt accacattga tcaatgcagc ttctcgcacg
    13081 atcacaggta caggtgaagc aggagccttg gtttcattga aaaaaaatca agctgttttg
    13141 tcagaaacaa ctattgatga tacaggggaa tttgttcttt ctatcccaga aaatcaactt
    13201 tttgcaggag atgtattaga aattgtatta aacgaccaag caggagaagc tactgctaag
    13261 ggtgtgcaga acaagccaag taccaacgat gaaattggga atcacaatcc aagtgatacg
    13321 ccagttgttt atcatgatgc cccgcctttt gcacctgcta cgaagatcgt agtagaaggt
    13381 ggtctctcat ttcttgcccc ttccaaactc gattttggtc agatcaaagc aactggtttg
    13441 acacaagaag catttggcca aatggatata caggaaaaat tatggattta tgatcagcga
    13501 gaaacgaaaa atccgtggat cttaacgata aaattatctc agcctttcac aaatgatgca
    13561 ggattttcta tgcaggatgt cctatatttc aagaaaggag aggagtatca attagtgaat
    13621 gaagaagaac tggaaattgt cagaggacaa aattcaacga atgtgcaagc agattattca
    13681 gaatatttaa ataacggtcg ggcgtttaaa cttgtcttaa ccaaagaaaa tcagatagct
    13741 ggtaattact cagcagagat aacatagaca ttagcagatg cgccgacaga ataaagatca
    13801 aggaggatga ttgatgaatc gaatatggaa taaaagtcat cgaaacaact gctctttact
    13861 tatgatcctt ctccttggat tcatcctttg gcagacacct gtccatgcct ccgaattcaa
    13921 ttttgcggta gattttgaat taccggctaa tcagattgat aagaacaaaa catatataaa
    13981 tgtaaggatg gagcctggga aaacacagga aatcccctac acggtcttta accgaacaga
    14041 taaatcagta acagttgaga cattgatcca ctccgctacg acgaattcaa acggtgtgat
    14101 cgaatatgga gaatcaaaaa gtaaatttga tgaaacatta agttatgata tgaaaaactt
    14161 agcaaaaaca gtgggagaaa taactgttcc tcctcaaagt gcggtcactg agacactttc
    14221 actgaaagcg ccagaaaaag agctggctgg tgtggtcgca ggagggatca cgtttcaaga
    14281 aaaaaaagag aacgtttcta acaaaagtac agttggtgtc gtcaatcagt tttctcaagt
    14341 gaaagcaatc ttgatttgaa atagcgaaaa agagtcttcc ccagatttga aattaaaaaa
    14401 agcttatgcg gatcaaagcg atggaagaaa tgtgattaag gcgaatcttc aaaatccaaa
    14461 tgcttcttat atgttcggct tgactacatc ggttgaaatc tacaaaaaag aaacaaaaga
    14521 gccttacctt tcaataaaaa aagaaaaaat agatgtagca cccaatacaa attttgattt
    14581 acttgtccca ttagaaggaa aaaaattagc tccgggacat tatcaagcgg ttgtgaaggg
    14641 tgcttggaaa gaaaaacgct ggaatctcca taccgatttt gaaataactg atgatgcagc
    14701 ggaccaattg aatgaaaagg atattgattt aaaaaatcag ccagaaacat ttgactggcg
    14761 atggctgata cttgttggag tcattcttat tggcttattt gctggattat ttattttaaa
    14821 agaaagaagg aaaaagaaat gaaaaaaaca attgcattaa gtaccgttct agctggaagt
    14881 ctattattat gtacacaaag tgtttttgct gagaataaga gctcagccac tacagaagga
    14941 acgatttctg tgaccaaacc agatgctgca aatcctgaag acgttgttcc agttcctcct
    15001 gttgatccaa atgatcctga tactcctttt acacctgacg aaccaaatca gggaacatcc
    15061 ggattactga cgattgacca agctccagat cttgattttg gaacaatcaa gttaggtaca
    15121 gcaaaaacag tatatgctgc attacaaagc ggaacggaca gtactggagc acaaacacaa
    15181 gtacagaatt tcgtacaagt aacggataaa agcggaaatt atgccggttg gaaattatca
    15241 gtcaaacgaa cagaatttat tggtacaaca tctgatacga ataaactaac tggttcaaag
    15301 gtgaaattca aaaacgccgt gattcgaaat agcgcaacta atagcagtgg aatgccatct
    15361 accgtttctg gaactggcgc tgaaggaatc gaaatcccag cagatcaggc agtagatcta
    15421 gtaactgcag gagcaaatga agggattggc acatggattt attcattagg agagaatgtg
    15481 gaacaaggga gacaatcagt ggaattattt gttcctgtat ccaattatgc tgtagacaac
    15541 tacgtttcaa cattcacatg gtcgttaaca gatgctccta cagaagagga agcgtaaaat
    15601 catatcaacg acttcaggga gtggagccga ttcaaggccc actccctgaa atctgctatg
    15661 cttacgtctc agctcttatt catcaactcg aagcagtttt ttggaagtca tggaaacgtt
    15721 cctttgtctt ttcaaagatc tttcgaccaa cgagtaagga gtcaccgttg aaaaattcta
    15781 acacataatg agcagaatca attttctgca attgcgataa gttgatacag taagatttta
    15841 aaagtaaaaa gtaagcatac ttttctaact ctgtcttcaa ttgttttaaa gaagtattca
    15901 ctaatttatc ttctgtagtt gttttgacca taacttggtt tttcaaacct ttgatacttt
    15961 caatatataa aatttcccga ggatacagga cgagacttcc acctttttga tcaataaaga
    16021 ttttatcgac atttacgatc tgctgttctt tccaattgat ctgttctagc acttgacgaa
    16081 tttgttcaga taaattcctg tcttttctga tatatccaat cggaaggatt ttccgattga
    16141 tgatctctac tgcaaaattc gtataagcgg tgaaaaaaac aatattacta tgtgcatttt
    16201 ttttacgtat ttgttcggcg acatcaatac ctgtgagtga ttgcttcaag tcgatatcga
    16261 taaagaaaac atcgtgatta tcaatagtgc ccaactggat caactgattg atttgagaga
    16321 tagaagtgag ctgcacgata ttctcgatat gatgattgac caattctctg atgatccatt
    16381 cgctgtgaaa ctggttatct tctatgataa aatacttttt catatgcagg ctcctattaa
    16441 aaaaatatgt gtacattttg aaacaaaaca atggaggaat aagatggtcg caacagtgac
    16501 actttatttg acctttactt tgattttaga tttaggtatc tatttattct tttcgaaaca
    16561 actgctagta aaaaacagct ttggttgtat agctttgatg gtggtgacac ttttacttcc
    16621 tatccctaaa gtgagctttc cttacctaat tggcttatta ttgatgtttc ttttttattt
    16681 tactacgaaa aacctgttta tcagctgttt gatcagtaat cttttttttg ctatcactgg
    16741 actcagcttt tttctggttt ttgatctgat ggattattta ggaaagagac atcttggaac
    16801 agcaagtttt tttgcactac ttatcgcatt tattttctat ctattagtaa aaagtataga
    16861 caaacagacg agatttctca acttgctttt tacttatcca actgaacact attttggagg
    16921 tatttgtatt ttattaagct ggggcgtgat ttacttggta ttgggaagtg ttcacttccg
    16981 ctcatctaat tatctgcttc tatctctttt gtcgatagtc atcagttttt tttctttgtt
    17041 tttttccatt atgttgatca gtttccaagt aaaagaaaga caacatcagg aatcgcttca
    17101 actgtatcaa ataaatgaag aatattacca tcatctagag gaattcaaac atgattataa
    17161 aagtctactg ttttcattaa aaattactct tcaggaaaat aaaaaagaaa cgttggaatt
    17221 tttagaaata ttagaagatc attctgcagc tatttttgaa aaaccgcaaa tacaacagct
    17281 aacaaatatt gtatccccag ctgtcagggg tgtcttttta aaatttctag aaaaagcaga
    17341 atcggagaaa atcccgatcc aagtagttat tcctgtcgaa gtgaaaacaa tcccgattga
    17401 tctggttgtt tttattcgct gtttatctat ttttatttct aacgcattcg atcatcgtgt
    17461 agccgatcag agtccgatta cgatcaatct gctggaagaa aaagagggat cacgttttag
    17521 tatagcgaac aaggcaaatc caacgaattt gacgctatcg gagatggtca aaagaggaaa
    17581 aacctctaaa aaaaatggcg ggttaggtct atacagtgcg aaaaaaatgt tggatgttta
    17641 cgaaaatgca gaactaaaaa tcgaattttc aaaacagaat cactattttt ttgtagaaat
    17701 gtatctggca tctagaaaga gcaaatcagc ctactgactt actgtcaaag gataagtttg
    17761 aggaaagtct acacggagat agagacaaca acacagcata ttcaaaagaa acagaagcgt
    17821 gatgaccgtt gtcacccttc tgtttctttt gctatgtagt taaacaaagt agttgacact
    17881 tccgctactt agtattagta cgaaagtata cttcatgata ctaagtagat aagaagtgaa
    17941 aagcggaacc cacgatcgtc aaaatgctaa ctgctttgct tacaccagat aaagggaaga
    18001 gcaatatcgc ttattttagg cgtggagaag caagcaaatc cctacgatca caaaaaaatg
    18061 ctgacccagc agttaagaga gttagaacaa gatgaaagta tccatcgaaa agcctataac
    18121 caagtcccgc ctaaagtaga gtactcgctc accgaagaag gaaaatcatt aagagagatt
    18181 ctagtagcgt tgtctgtttg ggaagaagaa cgtatcgaaa aacaaaaagc ctcaagggaa
    18241 gaagacacgc tactgcatac acatggtggc tacctaaatt attgattttc tatgacattt
    18301 attttaaata aaagaaaaca ggagtttttt taaaagcatc atctattttt tatgtaaaaa
    18361 aatggtatga ttaatcaagt aagaagtgat tggaagaagg caagcaaatg aatagtatgg
    18421 aaaaagtcaa ccagtttaga gatgaacgta attggcgaca atttcataac gaaaaagatt
    18481 tggctatctc tatttctttg gaagcatctg aattgttaga actttttcaa tggaaaacgc
    18541 cggaagaagt aaaagaaaca caattagaac gaatcaaaga agaactggca gatgtattga
    18601 tctattcata catgatggca gacaaccttc acctggatct agatgagatc attgaagaaa
    18661 aattgatcaa aaataatttg aaatatcctg tagaaaaaag cgcaggtgta cgaaaaaaat
    18721 acacagagtt gtagaaatgt gtcattcggc tgttggaaag agcaaaagaa aaacagtaaa
    18781 atgagtctgg agggagagaa aatgaaaaaa aaaggaaaag caaaaagatg gctagtcaat
    18841 atcctcttgt tcctcttgtt attagtagga ctagctttga ttttcaatga acagatcaag
    18901 gattattttg tcagagagac aggagataaa tatgctatag cgaatgtaac aaaagaagat
    18961 ctgaaaaaga ataacgataa agatgtcagt tttgactttg atgcggtaga accaatgacg
    19021 acagaagggg tcatgaggtc gcaaatgaga ggaacagatc taccagtgat tgctagtatc
    19081 gcagtccctt cagtttcaat caatttaccg gttttcaaag gcttggataa tacgtcacta
    19141 ctttacggag caggaacatt atctccagat caagaaatgg gaaaaggaaa ttatgcctta
    19201 gcaagccatc gtgcaacgaa ccctgaattg ctgtttacac cgctagaaaa tttagagatg
    19261 ggtgccaaga tctatttgac agatttagaa aatgtgtata catacaaaac attttttaaa
    19321 gaaaaagttg ctcctacaga tacccaatta ctgaatgaag tcgagggaaa agaaattgtc
    19381 acactaatta cttgtggcga catggacgcc gtcacgcgac tagttgtaca aggagaactg
    19441 gaaagtgtta catcgataaa agatgcgaca gatgatatga gatctgcttt caatctagag
    19501 acaaaaacat tttaggatac tgggacataa gtcgttacag attaaaaaca gccaaaggat
    19561 atgaatcgat aaggaaaaac caatttgctg aaaaaaagag aaacgcaaag aggtgcatct
    19621 ctgatttggt tgttttctag atagacttgt gttccagttt ttttattttt tatatgaaaa
    19681 ggcttgcata aataaaaatt cgatggtatg atgattttga ataagaaatg gattgttact
    19741 gtacggcagg caaaaccaga attcagctaa gaaacagtag gcgaattcta ggttttttta
    19801 tttttcttga gagggcgaag caaaatgaaa attgataaaa ttttgaataa caatgtcgtc
    19861 atttcgaaaa atggattcgg ggaagaagtc gtttgtatgg gaaaaggact agcttttcaa
    19921 aaaaagattg gggacgagat ttcgccagaa gcggtccaaa aagaatttgt tttaagagat
    19981 tcttttgcta aaaaccaatt ccagcagctg atggctgata ttccggcaga ggagatcgaa
    20041 tgggtcaaac aagtagtcga actggctgaa gataaactaa aagttgaatt ttcgcctaat
    20101 atttatctga cattgaccga tcatcttcat tatgcgatca cacgagcaaa agaaaatatc
    20161 caactgccta atccattatt atttgaaaca aaaaaatttt atccgaaaga atatcaagca
    20221 gcgaaagagg ctcttttgtt cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa
    20281 gccggtttta ttgcctttca ttttgtgaat agccaacaag gaaacgaaga catgcaagtg
    20341 acgatgaccg ctaccacaat ggtaagagat atactgagta tcatcagtaa attcttcggc
    20401 atcgtgttcg atgaagaatc tttgaattat cagcgtatca ttactcatct gcagtttttt
    20461 gcccagcgtt atctcaaagg ggaaggatct gacgagcaag atgaatttct ctacgcatta
    20521 gttcaaggaa agtatccaaa agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga
    20581 caaacgcaaa aacaggaaat ggggatcgca gagcagattt atttaacgat tcatattcaa
    20641 agagtagtaa gtgagaaaaa aagcatccaa tcataaggat tgttactgta tggcaggcaa
    20701 aacctggatt gaaaaaatag gttcacgaat gtttgtgact gtttttttca atctgggttt
    20761 ttatttttta aa
//
LOCUS       DAFELK010000051        20681 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFELK010000051
VERSION     DAFELK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20681
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.053"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            131..505
                     /locus_tag="LP433_002152"
     CDS             131..505
                     /locus_tag="LP433_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL2006291.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="LP433_002153"
     CDS             complement(619..1248)
                     /locus_tag="LP433_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2006292.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="LP433_002154"
     tRNA            complement(1382..1454)
                     /locus_tag="LP433_002154"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="LP433_002155"
     tRNA            1668..1741
                     /locus_tag="LP433_002155"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="LP433_002156"
     CDS             complement(1879..2043)
                     /locus_tag="LP433_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006293.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="LP433_002157"
     CDS             2338..3666
                     /locus_tag="LP433_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBL2006294.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="LP433_002158"
     CDS             3868..4701
                     /locus_tag="LP433_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBL2006295.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="LP433_002159"
     CDS             4717..5454
                     /locus_tag="LP433_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBL2006296.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="LP433_002160"
     CDS             complement(5609..6577)
                     /locus_tag="LP433_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBL2006297.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="LP433_002161"
     CDS             6809..7642
                     /locus_tag="LP433_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBL2006298.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="LP433_002162"
     CDS             7676..8515
                     /locus_tag="LP433_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2006299.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="LP433_002163"
     CDS             8541..9101
                     /locus_tag="LP433_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL2006300.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="LP433_002164"
     CDS             9300..11021
                     /locus_tag="LP433_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBL2006301.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="LP433_002165"
     CDS             11186..12328
                     /locus_tag="LP433_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL2006302.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="LP433_002166"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="LP433_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBL2006303.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="LP433_002167"
     CDS             14128..14775
                     /locus_tag="LP433_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL2006304.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="LP433_002168"
     CDS             15168..17813
                     /locus_tag="LP433_002168"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBL2006305.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="LP433_002169"
     CDS             18123..19436
                     /locus_tag="LP433_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBL2006306.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="LP433_002170"
     CDS             19426..20079
                     /locus_tag="LP433_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2006307.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..>20681
                     /gene="radC"
                     /locus_tag="LP433_002171"
     CDS             20134..>20681
                     /gene="radC"
                     /locus_tag="LP433_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL2006308.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNV"
BASE COUNT         6973 a         3458 c         4310 g         5940 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg t
//
LOCUS       DAFELK010000052        20529 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFELK010000052
VERSION     DAFELK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.054"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(541..1557)
                     /gene="tsaD"
                     /locus_tag="LP433_002172"
     CDS             complement(541..1557)
                     /gene="tsaD"
                     /locus_tag="LP433_002172"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBL2006309.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(1554..2018)
                     /gene="rimI"
                     /locus_tag="LP433_002173"
     CDS             complement(1554..2018)
                     /gene="rimI"
                     /locus_tag="LP433_002173"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL2006310.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2025..2567)
                     /gene="rimI"
                     /locus_tag="LP433_002174"
     CDS             complement(2025..2567)
                     /gene="rimI"
                     /locus_tag="LP433_002174"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL2006311.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(2551..3273)
                     /gene="tsaB"
                     /locus_tag="LP433_002175"
     CDS             complement(2551..3273)
                     /gene="tsaB"
                     /locus_tag="LP433_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBL2006312.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(3464..4444)
                     /locus_tag="LP433_002176"
     CDS             complement(3464..4444)
                     /locus_tag="LP433_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2006313.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(4468..5952)
                     /gene="galT"
                     /locus_tag="LP433_002177"
     CDS             complement(4468..5952)
                     /gene="galT"
                     /locus_tag="LP433_002177"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBL2006314.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(5964..6953)
                     /gene="galE"
                     /locus_tag="LP433_002178"
     CDS             complement(5964..6953)
                     /gene="galE"
                     /locus_tag="LP433_002178"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBL2006315.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            7202..7369
                     /locus_tag="LP433_002179"
     CDS             7202..7369
                     /locus_tag="LP433_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBL2006316.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(7431..9242)
                     /locus_tag="LP433_002180"
     CDS             complement(7431..9242)
                     /locus_tag="LP433_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBL2006317.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(9239..9604)
                     /locus_tag="LP433_002181"
     CDS             complement(9239..9604)
                     /locus_tag="LP433_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBL2006318.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(9767..10162)
                     /locus_tag="LP433_002182"
     CDS             complement(9767..10162)
                     /locus_tag="LP433_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL2006319.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(10180..11142)
                     /locus_tag="LP433_002183"
     CDS             complement(10180..11142)
                     /locus_tag="LP433_002183"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBL2006320.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(11142..11354)
                     /locus_tag="LP433_002184"
     CDS             complement(11142..11354)
                     /locus_tag="LP433_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBL2006321.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(11375..12073)
                     /locus_tag="LP433_002185"
     CDS             complement(11375..12073)
                     /locus_tag="LP433_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBL2006322.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(12093..12635)
                     /locus_tag="LP433_002186"
     CDS             complement(12093..12635)
                     /locus_tag="LP433_002186"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBL2006323.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(12767..13772)
                     /locus_tag="LP433_002187"
                     /pseudo
     CDS             complement(12767..13772)
                     /locus_tag="LP433_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(13769..14758)
                     /locus_tag="LP433_002188"
     CDS             complement(13769..14758)
                     /locus_tag="LP433_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL2006324.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(14755..15561)
                     /locus_tag="LP433_002189"
     CDS             complement(14755..15561)
                     /locus_tag="LP433_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006325.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            15727..16683
                     /locus_tag="LP433_002190"
     CDS             15727..16683
                     /locus_tag="LP433_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2006326.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(16760..17278)
                     /locus_tag="LP433_002191"
     CDS             complement(16760..17278)
                     /locus_tag="LP433_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2006327.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(17366..17515)
                     /gene="rpmG"
                     /locus_tag="LP433_002192"
     CDS             complement(17366..17515)
                     /gene="rpmG"
                     /locus_tag="LP433_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL2006328.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            17743..18189
                     /locus_tag="LP433_002193"
     CDS             17743..18189
                     /locus_tag="LP433_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL2006329.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(18384..20279)
                     /gene="asnB"
                     /locus_tag="LP433_002194"
     CDS             complement(18384..20279)
                     /gene="asnB"
                     /locus_tag="LP433_002194"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBL2006330.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6125 a         4391 c         3546 g         6467 t
ORIGIN      
        1 ttatcagggt cactgcttat tttcctccct aaaacttctg aaagatccgg cagttttaga
       61 tcactgggca agactcaaag attttctatg tgtgtttcag ttatgtaata ttcactgttt
      121 gcaaaaaata ctgatagatt aactagagga agcgtcttgt cctcatccga cctagattat
      181 tcgatattcc tcgacaataa acgattaatc agtgagggca atcagaggaa cggataatga
      241 tgaataagct gtaaaaaata gggctttgac aaaagcgtgt cacagccctt atttcgatta
      301 aacggtgtgt acctgtcaac tcttcggtca caagtcataa tgttcataaa catgaggagc
      361 tgttttttga aattgttcct tgtgaatcag agttaaacga caggcttacg aactcttgat
      421 taaacggcgt tcaaaagctt gcatacgcgg taataagaac agccaggtca aaaacatgag
      481 aagccgtttt tcctgggctg ttcttattac ttgatgcagg gcagattttt cacaacctct
      541 ttattcagat aaaaccaagc ttggatcagc attcaactga tagctagcaa aatttctttt
      601 ttgcatttcc acatgtgctg ctgctccaat cattgcagca ttatctccac aaagtcgaag
      661 agggggaatc actagttcta cctcagggag tttagttgcc aaagcatcct gcaatccttc
      721 acgcaaccct tgattggccg ctacacctcc agctacaatc agttgcttga ctggataatt
      781 ttgacaagct cgaagtgttt tagtaatcaa tacatcgatc acacttgctt gaaagctagc
      841 tgctaaatca tttttgtcta gatcttctcc acgctgttgt gcattatgca ccaaattgat
      901 aaatgcactt tttaatccgc taaaactgaa atcataatta tcttcatgga tcatcgctcg
      961 tggaaaatgg taattatctt ttccctgatg agctagctga tcgatttctt ttccgcttgg
     1021 gtaagaaaga cctaatactc ttccaacttt gtcataagct tctcctgctg cgtcatctct
     1081 tgtctcccca atgatttcat atgatccatc ttcttgcata tagactaatt ctgtatgtcc
     1141 tccgctaaca agaagtgcca tcaatggaaa ctggaatggt ttaaccagac gggctgcata
     1201 gatatgccct gccatatggt ttacaggaat aagcggcaat tggtgtgccc aagcaaaagc
     1261 cttagctgca gaaataccaa tcagcaacga gccgacaagt cctggtccat aagtgacagc
     1321 gactgccgat aaatcttctg ccgacacacc agcttctacc agtgcatctt ccaagcataa
     1381 ggtgatttgt tctacgtgat ggcggctagc tacttcagga actacgccac caaaacgttt
     1441 atgactgttt atttgagaag caacgatgtt agataagatc tctgttccat ttctaacgac
     1501 cgctacactc gtttcatcac aacttgattc aatcgccaga atcaattctt cattcatttc
     1561 atcgtctccg tttttaactt tctgctcata atgatcgcat cttccgtcgg attgcgataa
     1621 tatgatttcc gtttacctaa tatacgaaac ttttctgatt cataaagttt tcttgctgct
     1681 tcattagata gacgtacttc taaaaaaaca tgcagcgaat cttttatttg ttccgtaatc
     1741 agtaattgta acaaatgccg tgcatgccct tttccttgtt ctgaaactgc aacagcaata
     1801 tttgtgatct cgacttcatc tattactttc gagtatccaa taaagccaca gatctggtta
     1861 tcttcaacta aaagcagata atcagagtga ggctgttgga tgtctgccaa aaactgcatt
     1921 ttcgtccaag gtgaaccatg tggataagca ttttcgctaa tcatccatac gcattctgcc
     1981 aagtacgctt catcaaaatc tttttttctg caaatcaact aatctcactc attttctaaa
     2041 agttttatca tatccaacgc atcttctttt gtttcagtgt aatatctttt tttgatcgtt
     2101 gttgcttgaa aacctaactt ccgataaagt ctttgtgcat cttgattact catacgcact
     2161 tctaatgaca tcgtctcaca gcgattcatt atagcaaagt tctcgatttc gtcaataagc
     2221 agcgaaccga ttcgtttacg ctgatatgcc ggtcgaacgg caatattcgt gatatggcaa
     2281 tctaaaccga acgctcttga accgataaaa ccaatcattc ttccattatc aaagatacct
     2341 agatatagat gaggaagcgg tgacttcaat tctgatataa aggcactttt tgtccatggc
     2401 aattcgccat tatagacttc tcgttcgaca tccagcagct ctttgatatc ttctgtagtc
     2461 aattctctta gtacgtaacg acgatcgatt tgttcgattg ttttttctgt ataaatcatt
     2521 ttatcttgaa aaaagcttct ggcatacgct ctaaattttt tcaacataac tttcgtctcc
     2581 aggtgtgtgc gtctccaacc atttttcttc tgcttctacc cgttttaaat agcgaggaag
     2641 aaaagcttgt ttctctgcaa ctggttcagc taaagcacct aattgagcca cagttacacc
     2701 acttggaata tcccatgctg gaactgtatt aatcatcgca ctaggcaata tttcctttat
     2761 ttcatagaag aatttgtgac aatcactccc gacgaaataa atagcttcat tcagcttttg
     2821 tagttgtgtg aacaaatcag aagcagaaat atgtacatct tcaagtacaa tttctaatct
     2881 attttctttc cagcggtatg ccccagcgta tacatttttt cttcgagcat caaacatggg
     2941 cacaataatt ttatccacac cgatgcaatt agccgcgatg gttttcagac tagatactcc
     3001 tactagctct ttatctaatg tataagcaat cgtttttgct gtcgttacac ctatacgaag
     3061 ccctgtataa gaaccgggac catcagaaac cgcgattcgg tcaatgtctt ttggacttat
     3121 ttgaagatct gcaaacaatt ggtcgattgc aggcatcagt gttacactgt ggttgcgttt
     3181 gatatttgtt tgtatttgtc caagaatttg ttcgtcttct accacaccga tcgccaaagt
     3241 ttggtttgca gtatctattc ctaatgtaat catatatttg atcctttctg ctatgacatt
     3301 ctcgccttcc attgtagcat acttttttat tctgaggatg aaaataccaa aggcaaaact
     3361 agtacaatga tacatgatta tctgctggcg ggcaaatttt gccccttcct gaaacacaaa
     3421 aaagctgcgg tatcacttca tttccccaca gcttttccat cttttatttc gttgattctc
     3481 gaataatcaa ctctgtttcc acaataatct ttcttgaaac cggtgctttg gaattactta
     3541 attgaagaat cgtctccact gctagctctc ccatccattc ggtataaact tttacagtag
     3601 aaagagaggg cgttacatat ttcgctacac tgacatcatt gaaacccatc acagaaatat
     3661 cttctggtac cactaaacct ttttcttgaa tcgctttcag tgcgccaatc gctaatgcat
     3721 cattagctgc aaaaagcgca tcaggaacat gcggattcgt ttttaaatac tgcttcactg
     3781 cttgatatcc tgactcgaca gaaaaatctg cttcgataat tggaccttcg tcgtagcctt
     3841 tttctgccaa aacttgttga aatgccataa ttctgggatc ttttagccgc tgatggtttt
     3901 tcttcgtata ttctgttcca gcaagcatag cgatatgttg cgctttatgg gagacaaaat
     3961 gttcaatgac tttttgaaca cttgacttaa agtcgacaac tagagagtcg attccttgag
     4021 aagtgccgtc agaatctacc aaaagcaagg cattttggga tcctttcatt tctaataact
     4081 gagcttcgtc gaattttcct agtgcgatcg ttccatctgt cggaagatca ctaatggaat
     4141 cccacgtttc tttcaataaa gtaacgtttg cttcttctgc ctttttttcg attcctagac
     4201 gaatagataa ataataaaga tcttcaagct cttccgtatc gtcgtaccac tggatcaggc
     4261 gaagcgtttg cttagtattt gcagcatttt tacgatgttt cgtataattt aagcgttctg
     4321 ctgcttcaaa aattttttgc tttgtggcta agccaacgga aagatcagga tcatagttga
     4381 gaactcttga aacagtagca ggagaaactc ctgccaactg cgcaatgtct ttaattgttg
     4441 ccatttgtct ctcctccttt tttacgttta taaaattgca gtaaatcgtt caaacgctgc
     4501 ctgtcctttt tcatctcgct tgaatactcc agcgtcttcc agtacacgtg caaaaacctg
     4561 acctacagat ttttgtacga catcggtgac cgtatctttc gtcaaatcag gatgttcttt
     4621 ttttaattgt tctgcccacg gacgatgata ttcagccatc tggttttctt ctcctaataa
     4681 gaaatgctct acttctacta gttctggttt caaacgaggt ggtaaaacag caagccccat
     4741 tacttcgatc aacccaatgt tctccttttt gatatgttgg acatctttat gtggatgaaa
     4801 aatcccatca ggatgttctt ctgaaacatt gttgtctcga aggacaaggt ccaactcaaa
     4861 gtaattgtcc cttcttcgtg caattggcgt aatcgtatgg tgtggtgtac catctgctga
     4921 aaaagctctg atagatactg tttcatccga atatgctttc cacttttcca atactgagtt
     4981 agctgcttca atcaacaatt ttttctctgt tgattgcaaa cggatcacag acatcggcca
     5041 tttcacgact cctgcgatga cttgcggata atctgctagt ttgataagtt tttctatcgg
     5101 tgcttttgcc ataggaaatt catgacgtcc tgcctgataa tgatcatgag aaagaatcga
     5161 tcctccaaca atcggcaagt cagcattcga accaacaaag taatgaggca agacttcagt
     5221 aatccgaagc agtctagcaa atgtttcctt tgtgattttc atcgggcggt gttgttctga
     5281 taaaatgatc gaatgttcat tgtaataagc ataaggagaa tattggaatc cccagctttc
     5341 accgtctaga ttcattcgaa taatccggtg attggtgcgg gctggatagt tcaagcgacc
     5401 tctatatcct tcgttttcca tgcaaagcat gcaggtagga tagtctactt ttaccgcctc
     5461 gcgttctgct gcgatttgtt ttggatcttt ttctggctta gataaattga ttgtgatttc
     5521 cagttcacca tactccgact ctgccggaaa tttgatgttt tttgcgatgg ctcttgtttt
     5581 gatgtagtca tttttcttac ttaaattaaa gaaatactca gttgcttcct ctgggctttt
     5641 cgaatagtgc tgtgcaaaga atgcattgac gactgaaggt ggcggtgtga gaaaatccat
     5701 taattgcgct tcaaaaatct cttgttctgc tggcaattct gaaagaacac cattttctct
     5761 tgccttagcg acaagctgat ccaataagtc tacagattct tccttaactg gtcttacttc
     5821 aatgctttct agagcatctt ctcctaccat ccctaaaaga cgattctgta aatataagcg
     5881 gtccatttcc atccatccgc cagcttcgat cgcaagtgtg gcaaaatcac aaatcgtttg
     5941 actgattgac atatctcatt cccctattct tcataaccat ttggatggct gacatgccaa
     6001 tcccatgctg ttttgataat tgctttgata tctgtgtatt caggtttcca acccagaacc
     6061 tctctcgctt tttcacttga agcgactaat cggctaggat ctccagctct tcttggtgct
     6121 atttctgctg gaatttcttt tcctgtcact tctctagctg cttctagcat ttccttgact
     6181 gagtatcctt tgctgctgcc taaattgaag aagttgcttt catttccttc tttcaagtat
     6241 tccaaagcta aaatatgtgc agcaatcaaa tcttctactt gaacataatc tctgatacat
     6301 gttccatctg gtgtatcata atcgtctcca taaacagcca atgcttttct ttgaccaaga
     6361 gctacttgta aaatgattgg gacaagatgc gtttctggtg tatgatcttc tccgatagat
     6421 gcatctgctt ttgctccggc tacattgaag tagcgcaaag cgacatagcg catgccatat
     6481 gcttggtcac accacttcat cattttttcc atcatcaatt tactttcacc atacggattt
     6541 ttaggattag ctggtgtatc ttctgtgatt ggagactctt ttggttctcc gtaagttgct
     6601 gcagtagaag agaacacgat tttattcaca ttgaactcgt gcatgacttc aagtaagatt
     6661 tgcataccgt atacgttgtt gttgaaatac atcaatggtt tttcgacaga ttctcctact
     6721 aaagagcttg cagcaaaatg gattactcct tcaatcggtt ccttttcaaa tacggaacgt
     6781 agaaattctt tatcccggat gtctccttca taaaaatgag catctggatg tactgcttgt
     6841 ttgtgacctg tgagcaaatt atctaccaca gctacttgat accccttttg aactagctgg
     6901 tctacagcgt gcgaaccgat ataaccggct ccgcctagta ctaaaattgt cataaaaaac
     6961 actcctttga ttagtaaaat tgtgtttgtt gattatatat aatttaaaaa aacgaagttt
     7021 acttttatgg tgaaaacaaa caaagtaaaa tttcgtaaat tcatatggta aatttataat
     7081 aaaacattta gtaaacattt tcaaggattt tttgcaaagg tttacaaaca aacgtaaaac
     7141 tagccttttt ttctcttttg ttccataata gatataacaa ataataaatg aggtggattc
     7201 aatgaaaaaa tttgtatctg gaatattagt aggaagtctg gcaacagccg ctgccgttgc
     7261 tggtttggtc gcttctgtga aaaaaacagt gatcgatcca attgacgaaa aagaagcaat
     7321 gatcgaagaa aaccgtaaaa aagcaatgcg caaacgcgtt tctcgttaat aattatttaa
     7381 aaacacgcat gaagacttgt gaaagaacag ataagtcatc atgcgtattt ttatttgtca
     7441 gtcaatataa gttgtgctat tttatctgcc tgtctcagat tccatggatc tgtataaggt
     7501 ctagctactg ctgcagttag ccaatccaca ccttcaacag gtattccata gcaataaaag
     7561 tcagactgga tttcccctga agcatcaatc acgcgattcg tacctcgctc aacatctata
     7621 gcttctgaat gataacttcc tgtattatct gaaaatgaaa aagggcgaac aagtttgttt
     7681 tccttcaaat tttttatgac aggattactt gaacgagaaa agcttgtttg tggcaatcga
     7741 gcttcaatca aatagcgact gctgatttct ttatcttgta gagaaataac atagcggttg
     7801 tgcttttgct gaatatcaaa tggcggttcg aacaaatgaa aaatacccgc atctatcagt
     7861 gctgctaatt ctttcgtccg aatgactggc ggaccgatcg ttaaaaagct atttagatga
     7921 gtaaaccatc cccatagtat ttctttgtat tcctttgcag aaaaaacgtg ccattcaata
     7981 gcctgccgga ttggatcacg ccagtctttt aatgcatcaa atgttgaagc aaatgctcct
     8041 gtgcaattgc ctttttccgc ttcttttatc tgcccttcaa taaatgctcg gctagcttct
     8101 gcaaaggact catcctgata ggtaagagga atttctaaat acgaccaatc ccatctataa
     8161 gggattagtg ctggatgctt tccgagacac tcctctgaag agagggagag aaaatcatgc
     8221 tcaaaatttt tctttggaat cggcaaatga tattcttcga tgattttctt gtaataaaac
     8281 aactcaacgt cttttttcag atagtcaaaa aatgtttcgc cagtcaaaaa tcccgactga
     8341 tgccattgct ccaggttttc ttttgttagt aaccgtggcc atgccattga tccgccttgc
     8401 ttttggtttc ttcctcgagg gtaataaggg agcccccttc ttgatccact gtatacaatc
     8461 ggttccttgc ctgatggatg atagacaagt tttccttttt cgttctcgaa gcgcccttct
     8521 cttgatactg taaacaatcc gacataatca aaaaaactta agcctagacc tcttaaaaag
     8581 acattttctt taggcggtat cttcgaaaga tcgacatctg caggattaga aggaagctga
     8641 tacagtaaat catttttctt tgcgtagtct acccacactc tttcttcttc tgtctcatca
     8701 ttttcccagt gaccgcttgc taaaacaagc tgatcgatag aatagctttg ctgatctgtc
     8761 tgtaaaagat aaccatcttt tcttttgctg acttttttta ctaaagaata aacaaactga
     8821 atagaagctg gaaattcttc ttgcaacttt gagaaaaacc agcgttgata gagtccgtat
     8881 aaacatcgag tagattgctg atctttttcc agacgattga tttcttctat aattagttgc
     8941 ttatttttgg ttaccgtctg ttcgatataa tctgtagcag gtcctttact ccattgaaac
     9001 aagttgggtc cctgtgttac caatcctcca ctggacaatg tttcatctgt aaaaagcgtc
     9061 acttgttgag aaacagaatt cattaataac tccggtggct gattcaaccg ccaaactcga
     9121 cctccaggac cattgggatc gaaaagaaaa agttcaagag aatgtctgtc ctgattatta
     9181 tggagaatcc tttctgctat acttaatcct ctaggtccgg caccaatgat ccctattttc
     9241 atttgcatgc ctccatttcg ataaattttt tcaataaaac agcatggttc tgatgttcat
     9301 tttttgcacc ataaacaaaa gtaatgactg gatgttcttt cataagttga ctgagtttaa
     9361 aaatagcttg cttcttttct tcttcgaaaa tcaattcttg ctggtatttc tttgcaaatg
     9421 aagcaaatcg ttctggtaca tggtcaaaag ttttgcgtgc ttcattacta ggtgcaattt
     9481 ctttcaacca cagatctaac tgcgcttttt cttttgaaat tcctcgtggc cagaacctat
     9541 ccacgagtat tctatagcca tcctcttttt cagcatcaag gtaaacacgt tttaatttga
     9601 tcatagttgt ttccttcttt ctgccttttc gcttagctta tatatgtaga taatagcaca
     9661 aaataaaaaa aatgaacggc acaactatcc attgcgccgt tcatgtgatc ttggtcaaaa
     9721 tctaatgatt gattcggttt ttaaagctgt catacaatca tctgttttat acttttttac
     9781 ttttgatttt tccagaccat ccgtcatatc cacccttaag taaataaatc tcttgataac
     9841 ctgctttacg taatttattt gctgtacgga tgctcaagct tttcttttga tcgtaaatat
     9901 agacaggctg gtcttttcga atagatccta atgaatcttt caaaacagtg taagggatgt
     9961 ttcttgcacc taaaatatgc ccagcatcaa acacatcttt ttcgcgaaca tcgattactt
    10021 gtgcttttct cattccttct cgaaattctt cttctgtcaa agtcgttgct gaacgcttgg
    10081 ccattactcg tagatagact tcccaaaaga tgattgcaag cacaatcaat agcaaaatga
    10141 tattaattac ccataaaacc atgtaatgcc tccgtttttt taagcaaatt tcaaggctaa
    10201 tgaggcagca ccaatgacac cagcttcatt accaagctct gctaatttga tttttgttga
    10261 ttctcttact tgcgggaaag taaattcttt aaaatatttc tctacacggc tacgtaaaaa
    10321 ttctcctgct gccgatactc ctccacctaa cacaatactt gacggattca atgtattccc
    10381 caagttggcg caagctaaac ctaagtagaa gcatacgcga tcaacaacca tcaatgcaaa
    10441 cggatcgtct tcttgagcca tttcaaagat atctttactt gttacttctt caccgttgtc
    10501 taacattgct ttcagttttg aatctcctgc gtattcttct gccaagtaac gacctagacg
    10561 taccacacca gtagcgctag acacagtttc taaacatccg cgtttaccgc aagtacattc
    10621 gaacccttca ggatccacag tgatatggcc gatctctccg cctgctccgc tcacgccgtg
    10681 aatcaaattt ccgccagcaa cgataccacc gccaacacct gttcctagag taacgaatac
    10741 aacgtctgga tcgttttctc cagcaccttt ccatcgttca cctaaagcag caacattcgc
    10801 atcattatcg atagcgaatt tgattcctgt tcctgcctcg atcagttttt tcacaaattg
    10861 aacttctgtc cagtttaagt tatacgcacc aataaccgtt ccagcttcgc tgtccacgct
    10921 tcctggggta cccatgccga ttccgataaa gtcttcggct ttcatattat ataaattcaa
    10981 acgatggttg attgattcaa tgatttcagg aacgatatgc ttaccatcat ccaaaatatt
    11041 ggtatcgatg ctccattttt gttgaatctc tccttctggt gttaaaattg caaattttgc
    11101 tgttgttcca cctaaatcaa tcccaataat cttcttgtcc attacaaatt tcctttcttt
    11161 cggctttctt caattcggtg ctctcttttt aatatgcgcc acgctgtcat gtatgtatca
    11221 tgatcaatca aacggctatc atacagatta cgcaattcga tagtcattaa ttcaatgtca
    11281 tagatgcgtg cacccacata gataaagatg ccaaattttt tgaacagctg ctgtacatca
    11341 tataagctct ccatctttaa gcacttcctt catattatac aagtaaacca tattttttta
    11401 aacccagtaa aatacatatt acaaaaagaa atacaaaaac tagtgtagaa agaatccttt
    11461 ggtgtatcga atagcttgtc tgttgtttcg gtagacccaa aacattccct aacactaatc
    11521 cgccaattag cccaccgaca tgtccccaaa catctacaga ggtatccaga agaccaaaaa
    11581 caaatgtcaa cacaataaat aaaagaaaat gtctgactag ctgctggatc gctgggttat
    11641 gtttaaaatg aaaccctaag ataaacaacg caccgaacaa accgaatatc gaagtactcg
    11701 caccaccaga cagaacattc gcttcgttaa aagcaaagct tgctgtattt cccattatcc
    11761 cgctgaacat ataaatcaag aaaaaacgcc aatggccata gattgcctcg atttgctgcc
    11821 ccataaaata cagtatcagt gagttcatta cgaaatgcat cagtccaaaa tggatgaaga
    11881 ttggtgtcac taaacgccac cattcattga agtgaacaag ataaggacca tacattccgg
    11941 cataataagg gatctcaagt cgcggaaata attccatcat gaggaagacc gctgtctgta
    12001 tccctaaaaa agcataggtc cataacggtc gtcttaacca tgcacgcaat tttatttgct
    12061 gttgataatt catgaaaacc tcccatttca ttttagtcaa taaacaattg ttggatcttc
    12121 tgatcaaagc tctccggttg ccattgttca ttcaattgtt cacgaaaaac aaggctacat
    12181 gtttttttat gaaaattatt taaataccgg tcgtaataac caccgccaaa accgattcga
    12241 taaccggctc tattgtagat aatacctggt acaatgagga gatcgatcat ctccggcaaa
    12301 tagagcttct ctgattgtgg ctcaagaaca ccaaaactcg aacgtacaag aacggactgt
    12361 tcatccattt cataaaacgc catctgacgt ttcggcaaag ttttaggtac aactattttc
    12421 ttttgttctt tttctgctcg ttggataacc ggctgtgtat ccagttcaaa ttcattcgat
    12481 aaagtcgtcc ctatcacttt tgctgacttc cagtactcgc tggcgaatag ctgtttatag
    12541 attcgctgtt ctttttcctt tttcttgcca cttttggcca gatttttcag cttttcgatt
    12601 cctttccggc gtaatcttac tttcaattgg tccaaaaact cacccttcct tctctcataa
    12661 aatggtatag gaaaaaaaga aaaatagcaa tcgaactttc aaataaatgc ataaatagaa
    12721 taaaaagaag acctagaaat gattggcctt ccttttttaa taaatttcaa ctgttcagcg
    12781 cgtgtttttg tctgataaaa agtgcataca gaaaatatgg cgcaccaaaa agggcaatca
    12841 aaattcctgt aggtacttcc ccacttggta gaatcactct agcaaccata tctgcactaa
    12901 gcagaaaaat ggaaccgaac aaaccgctca gaacaaaggt ccagttattt tctttacgta
    12961 cgactagctt cgcagcatga ggagctagta gtcctacaaa agataaacta cctgtcaccg
    13021 ctacactacc gcttgccaaa gcaacagcta acaacaaaag gattttttga cttttagcca
    13081 cgttaaggcc taatccttgc gcgcgttctt gaccaaatga tagcaatcca atcctctgtg
    13141 cataaagtcc tcctagcgga attaagataa ccgcccatgg aagcaatgcc caaacataag
    13201 gccagctcgc accccagatt gatcccgcta accatgcatt cacaaatcca taattttcct
    13261 tagataattg gatcgtgcat agcaatgtta atgcagaaag gccggcatta acggcaatac
    13321 cggacaataa gattcgattc atacccaaaa agccatttcg atcataggcc gcaagattag
    13381 acacagcaag cagctaaaac accacctaga aaggctacaa ctagcaatag aaacggcagc
    13441 gaatagtgcg aaaagaaacc taaataaagc atcactaaaa atcctgctcc ggcattaatg
    13501 cccaatatac tagaatctgc caattcattt cttgttactc cttgcaagat ataaccagaa
    13561 acgccaagac aagctcctgc taataaactg atcagtaatc gaggaactcg aaattctcta
    13621 acaatcagcg ccaaagaaga tgattctttc cctatgaacg tggcaaaaag ctgatccagg
    13681 taaataaaag gcgtaccaat cattaaacta cctatagaca ggatgacaag tacaaaaagc
    13741 aagaaataga acgtccaata tatttttttc accgttgttc cctccttact tgtatcagta
    13801 aaaacggaac gccaatcaat gcaatgacta atccaaaagg tgtttcaaaa gggggattga
    13861 tcatcctcgc tgtaaaatcc gccaacataa ccaatccacc gccaactaaa aaagagacag
    13921 gtagaacata acgatagtcc gttccaacca ttccgcgaac aactggcgga accaacagcc
    13981 caataaatga aacaggtccg actaacgaaa cggcaatggc tgctaacact gcaactagac
    14041 agaaaacaat caaccgcgtt cgtttaggat gacttccaag agctaatgca tgtgtttcac
    14101 tcaaatgaat caaagatatt gcttttccta atgaaaaaga aaccaaaaca gcaagtatat
    14161 ataaaggaaa caatactgct aattgtttcc atgtgatatt ggcagctccg cctacaaacc
    14221 aaaaagcaag atcctgctgc agattaaaga attgggtaag tgcttggctg atagcagtaa
    14281 aaaaagaact aatagctacg ccagctaaaa tcagctgtaa aggattcatg cccattttcg
    14341 aaaactgcaa aaaaccaaat acgagcaaag ttacagcaaa agaacctgcc aatgacatta
    14401 gaaacacaga aaaatcagaa gctttaggcc aaaaagcaaa actaagggcc attgccaacg
    14461 aagcacccgc gttgattcct agtaagcctg aatctgctaa aggatttctt gtcactcctt
    14521 gcatcaatgc accgctcaat gcaaaacaac tccctacaag aaatgctccc gccacacgag
    14581 gcaaacgaat atttcgtatg atttggtgac tttgttttga tctatcaaaa tcaaacaacg
    14641 cctgccaaaa atctgctttt cccacagtcg ctgcgccatt tgaaagagca acaaaaaaaa
    14701 taatcaaaag aacaaaacag accaaaagca ggagtctatt tttcttcata gtcctcataa
    14761 ttgatcctcc tgctcttttg gcaacaaatc ataggttaga aaaactggtt tatttgttct
    14821 tggaagcgtg acaatcgttg catcaatctc aaatattttt ttcatacact cttttgtgat
    14881 cacttcttca ggtgtacctt ctgtgatcaa cttaccgttt ttcattgcta ataaataatc
    14941 tgaaaaacgt gaagcatgat taatgtcatg aatcgacatc aagatcgttg tttgtttcat
    15001 ttgattgatt tcagtcaata actgtaggat ctctaattgg tgtgccggat ctaaaaatgt
    15061 tgtcggttca tccaagatca agatatctgt ttcctgagca agcgccatag cgatccagac
    15121 acgctgggtt tgtccaccag acagcgttgc gatatcccgc atacgaaatc cagctagacc
    15181 tgtagcatcc aacgcccact cgattgcttc atgatcttgc gtgtccatgc cactgaacag
    15241 tttttgataa gggtatcgtc cgtaagatac tacttcttct actgtcatac ctgtagggtg
    15301 ttcactagtt tgtgctaata atgtaatttt ttttgcaagt tcttttgaac tgtatgtaga
    15361 gatatcagag ttattgacaa tgatctttcc tgatttcaca ggtagtatac gggtaaaact
    15421 tttcaataaa gtagattttc cacttccatt tggcccaatc aaactagtga ttttcccttc
    15481 aggaatcgta acagacatgt tttcaatgat ttttttgttt tcgtagccgg ctgcaatgtc
    15541 agctgctctt aatctcgtca tttcacccat cctttcgctg aaaatcattc tcaattatga
    15601 cgctgtttca acatttcgtc aagcgctact ttcatatcta tagccaaatg aagcggttga
    15661 cagcgttcga aatatcagga ataataacca atgagaaaga ttctcaatta tgttaggagg
    15721 aaagaaatga aattaaaaac aaaagtattc acattatcta gcatattgct gctggctgga
    15781 gtactgagcg cttgctcccc ctcttcagat aaagaaacag ctacaactgc caattcgacg
    15841 acttcatcca atagtactca tacagtcaca gatacacttg gacataaagt agagattcca
    15901 aacgcgccca aacggatcat cggcagttac ttagaagact atctgattgc actaggggaa
    15961 aaacctatcg cccagtggac tgttggcagt ggttccattc aagattatct gcaagatgat
    16021 ttaaaggatg tcccaacgat ttcttatgac cttccttatg agaaagtgtt aagctttgag
    16081 cctgatttgc tgttgatttc ttcttccgct actgtcgaag gcgggaaata cgaacaatat
    16141 agcaaaatcg cgccaactta tgttgtaaaa aacggaacag atgtcacatg ggaagaacaa
    16201 ctaaaagatg tcggcaaagc tttggcaaaa gaaaaagagg cagaaaaaat catttccgat
    16261 tatcaaaaat ccatcaagaa aactcgagaa gaactagcag ataaaatcga gaacaagaca
    16321 gctgcagtgt tgtgggtgac caacaactca gcctttatgg tcagcaaaaa tcggtcaagt
    16381 ggaagaatcg tatacgacga tctggaattt ggtgttcctg atctagtgga agaggtctcc
    16441 aaaaaagcca cttctgactg gtctgctgtt tcctctgaaa agctagctga attagatgct
    16501 gactacatca tccttgtgaa cagtgacaaa gatgctgcca tgttcaatga accaagctgg
    16561 aagaatctta aagcagtgac agacaatcat gtactgcaat tcggacctga atctagttgg
    16621 ctatataacg gacctattgc cagtcaggaa atggtcaatg atatcaaaga aaaactaaat
    16681 tgattttaac taaaaaaaga atcttcacga ttagtcgtga gatgcttttt ttcttattaa
    16741 caaactagac gcatagattt tattcttctt ttgaagcaac cctatttttt actctttccc
    16801 atttttgaaa acgatgggca tatagatttt cttgatccgt tatcccctca tactcctcta
    16861 taagggcgaa gtctgaaaaa tcaatattcc caatatacgt atcgccttca aacgtgctat
    16921 cgatcaatgt tcgccagatc cgaccagtgt aaggaagaag ttcttgaaaa atccgactac
    16981 cacccgaaac atagatatct tctgagatcg tttgactata cgacaaaagt tcatcgatcg
    17041 aatgcattac ttccgcattt tctttcgtgc gaaaatttgg ttgcgttgtc aacacgatga
    17101 tatggcgata aggaagtgaa agatccccca ttccttcata ggtctttctt cccatcacta
    17161 aaattcgatc cattgtatgt tcgcgaaaga aacgcatatc atttggcaat cgccatggta
    17221 acaaaccatt tttgccgatc agaccatttt tatcttgtgc ccacatggaa ataaacatat
    17281 tatccgctcc ttatgatttt agatgttttg agataaaaaa agtctcaatt ctttgaccag
    17341 caaggaattg agaactttaa aaacattatt ttgtttcacg gtgcaaagta actttgcgtt
    17401 cgcgtgggca atatttttgt ttttccaaac gatcaggatt gttacgtttg tttttgcttg
    17461 ttagatagtt acgttcttta caagaagtac actctaaagt gatgtttacg cgcatgtttt
    17521 tccctcccat ttttacaaga atcctctaag atgactctca gacttgatta tcttaccatg
    17581 attttttcta gattgctagt gtttttcacg attttgttaa gtaaaactac ttgacgataa
    17641 atacaacggt tttacttctc aaacaaaatc tttttctttt tgtataaata cccttacact
    17701 tgtttatata gattatgttt tttaataaag ggggatacta atatgccatg gaacatgaag
    17761 gactttcctg catcaatgaa aaacttagat aaattgacaa gaaaaaaagc aatcgacatc
    17821 gcaaatgcat tattagatga agggtaccct gataaccgtg cgatcccaat tgccattgat
    17881 caagcaaaaa aatggtatga agatgctagt gaatcagaaa aacgaacttt cgaaaaagaa
    17941 aaaaatccaa gcaagacgga tgaacacgat acgaatcctc gtgctggaaa actgcttgat
    18001 tcagatgtga tcgtagaata tgaggaagaa caatggatcg tgaaatctaa aggggcaaaa
    18061 aaggcaagca accattttga tacaaaaaaa gaagcaatcg aaaaaggaaa gcaagtagca
    18121 caaaacaaag aatcaacttt gttcatttat aaaaaagatg ggacaaaaga aaaagaaatc
    18181 gattattgaa catatgtaaa ggggttgtga cgaaaatcgt gtcacaaccc ccttatgttc
    18241 gaaacaatgg tgttcctctg ccaactccga accataagtc ataatatcta taaaacggga
    18301 agagctgttt tttgaaattg tttcttatca ctcagtgtta aacggtagga gaaaacctct
    18361 tttttattga tatttgattt tcatcaaaca gtcacatagt cgattgcttc tgcttgcgga
    18421 atcgtttcat ctacaaagta gactttatac catgtcaaga aactgaagat tgtccagatt
    18481 tttctttgct cttctttacg tccttcgtga tggtcatcta gcaacttcat gattttttct
    18541 tgatcaaaaa attcttttgc aaaatctgct tcgaataatg ctttgacttg ttcgtagccg
    18601 tgttcttctt tcaaccaagc tttgattggc acagggaatc ctaatttcac acgattcgac
    18661 cattcttccg gaagatgttt gttcgcagct tgtctgaaaa tatcttttgt gttgttttga
    18721 ttcaataaaa acttacttgg tatttgttga gccaatttca tgacttcgat atccaataaa
    18781 ggtactcgga cttccaaaga acttgccata gaaagtttat ctgcctttaa caagatatct
    18841 tttggcatcc attgatgaag atcgacatat tgcatcttat tgacttcatc tttgattcct
    18901 tctgttttct cgtaatgaac agtcatgatt tcatccacag atggtgctgt ttgatatttt
    18961 ggtgttaaca cttctgatgc ttctgattct tcgaacactc gagcatgacc gataaaatat
    19021 tcttttgcag gagcaagtga ttcatataaa tggatccgtc catggaaatt tttcattttt
    19081 ccgattttac gtcctaaatt atagcgtgtt ccttttggta attttttcaa tccttgagca
    19141 atcacacgga tgaattttga attcgtatgg aatccatacg tttggtatcc cgcaaacagt
    19201 tcatccgccc cttctccaga ttggactacc cgcacacttt gtgaagcaag atttgctaaa
    19261 aagtacaaag gtacgcaaga aggatttgaa tcaggttcat ctaagtgata ctggatcaaa
    19321 gggaatgctt tgaacgacat gtctccgtcg atcactgctg ctgtattatc taagtccaat
    19381 agttcggtta gttttctggc ttcaatcgct tcattatagg ttttatcatc aaacccgatt
    19441 gagaaagaat gatctggttt caatacagag gttacataac tggaatcaac cccgctggat
    19501 aagaaagaac caacttctac atcactgacc gtatgtgctt caatagaagc ttgaacggtt
    19561 tcgtcgattt tttcgatcca ttcttgtcgg gaatgcgttt cttttgtttc aaaatctgca
    19621 tcccaatatt gctgaatgtc tagttttcca tctttatacg tataataatg gccttcaggc
    19681 aaacgataga catctttgaa gaatgtttcg ccgtttaatg gagaatattg gaaagtcata
    19741 taaggtttca acgcttcttt gttcaattct ttgttaaaat caggatgagg cagaaaactt
    19801 ttgatttctg aaccaaacat aaatgttccg ttcatttctg cataataata tggtttgatc
    19861 ccaaagtggt ctcttgcacc gaataactca ttcttttcat tatcccaaat agcaaaagca
    19921 aacattccgc ggatcttttg caataattct gttccccatt cttcgtaacc atgcaaaagg
    19981 acttctgtat ctgcatgtgt ttgaaaaacg tggccagctg caatcaattc ttctctcaaa
    20041 ggctggtaat tatagatttc gccattaaaa ataatgatct ttgtccgatc ttcattgtaa
    20101 ataggctgag taccgccctc taagtcaata atacttaatc ttctgaatcc taaagcaaca
    20161 tgtttatcga tatattctcc tgaactatta ggtccacggt gaacgattcg atccatcatt
    20221 gtattaataa ttgttttttt gttgtccttg tcgttaacaa aacctacaat accgcacatt
    20281 taactttcac atcctaatat aaaattactg tttatttcat tcatatgcat cttatcatag
    20341 aataaatagc ggacgaatat tttctctctt acaatttcgt cacgtgaaaa caaaagatga
    20401 aagtttctgt ttttacagaa aataaagtcc caatatctaa tttaccatgt tttctttttt
    20461 gaggctacct tattctcttc gtgttaaaaa aatattagtg gatgctattt ccaaaaaaaa
    20521 cagcaaaaa
//
LOCUS       DAFELK010000053        20466 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFELK010000053
VERSION     DAFELK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.055"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(41..484)
                     /locus_tag="LP433_002195"
     CDS             complement(41..484)
                     /locus_tag="LP433_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2006331.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(500..1660)
                     /locus_tag="LP433_002196"
     CDS             complement(500..1660)
                     /locus_tag="LP433_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2006332.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            2167..3867
                     /locus_tag="LP433_002197"
     CDS             2167..3867
                     /locus_tag="LP433_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006333.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(3969..4802)
                     /locus_tag="LP433_002198"
     CDS             complement(3969..4802)
                     /locus_tag="LP433_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBL2006334.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(5106..7271)
                     /locus_tag="LP433_002199"
     CDS             complement(5106..7271)
                     /locus_tag="LP433_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2006335.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKNPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7531..9825
                     /locus_tag="LP433_002200"
     CDS             7531..9825
                     /locus_tag="LP433_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL2006336.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            9818..10483
                     /gene="pgmB"
                     /locus_tag="LP433_002201"
     CDS             9818..10483
                     /gene="pgmB"
                     /locus_tag="LP433_002201"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL2006337.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            10476..11483
                     /locus_tag="LP433_002202"
     CDS             10476..11483
                     /locus_tag="LP433_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL2006338.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            11505..12524
                     /locus_tag="LP433_002203"
     CDS             11505..12524
                     /locus_tag="LP433_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2006339.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(12812..14173)
                     /gene="nhaC"
                     /locus_tag="LP433_002204"
                     /pseudo
     CDS             complement(12812..14173)
                     /gene="nhaC"
                     /locus_tag="LP433_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
     gene            complement(14282..15703)
                     /locus_tag="LP433_002205"
     CDS             complement(14282..15703)
                     /locus_tag="LP433_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2006340.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(15946..17823)
                     /gene="tdc"
                     /locus_tag="LP433_002206"
     CDS             complement(15946..17823)
                     /gene="tdc"
                     /locus_tag="LP433_002206"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL2006341.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRNVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(18114..19370)
                     /locus_tag="LP433_002207"
     CDS             complement(18114..19370)
                     /locus_tag="LP433_002207"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBL2006342.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(19482..19687)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            19926..>20466
                     /locus_tag="LP433_002208"
     CDS             19926..>20466
                     /locus_tag="LP433_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006343.1"
                     /translation="MKKQGTRYMEKKQKIILGATSALTIVILILSLFFVIRSSTKKEP
                     IIPEKKITEKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQT
                     LKKEKEQLIDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQL
                     YQNDFVLVNLNDLIQKDEQG"
BASE COUNT         6171 a         4291 c         3662 g         6342 t
ORIGIN      
        1 aaaaaattag gctgggagca ttatttcgtt attctgttca tcaaaaatca gcgttttgat
       61 tccatttcat cacaagttcc tcctcattta ctgcttcatc tttttgctgt gtttgaattg
      121 taaaaccttg tgaaagatag aaatgaatag ctgattgatt tttttgatag actgtcaaag
      181 tcagtgtttt attggtttct tttatttttt tcattagttg cgtaccgatt ctttgttgcc
      241 ggtattccct tttcacaaag attcctgcga taaactgatc aatcacccca gcaaaaccaa
      301 taatttcttg atctatttct gctaagtaaa tcactgcatc tggtaaagct ttcctaacag
      361 attctacttg attctcccaa taagttgatg gaatgaattc atgagaatcc aagttagcat
      421 gcagccaaat cgatagaaca gattccagtt ctttggcaga caattttgtt gttgtgcgga
      481 tcattttttc tctccttact tattcattga ttttaaaata aaaaccattt ttttgaagct
      541 cttttacaag ttttcgcccc tcaaaaaagt atatcttctc ttgttttact tttctaatac
      601 caaaagaaac agcaacttta ggatcatcag ctgaaacgat tcgataagtt ccaccaggca
      661 attgatccag cttgactttc ccatgatggt cgctttgtac tgaaaacggc acaccatttc
      721 tagtaagtgt ttttttctta tgtttcaaaa tgaatgaact accatttacc ggtttccctg
      781 acgaatcact aataataaat gaaaaatcaa gcactttttt acttaatcta tactgataga
      841 ttagtcgtcc gataaacact aacagtatga ctacagctat tatcgttcct gcaagaataa
      901 accattgccg catggttctt tcctgatttc cttttccttc ttcttttttt accgattcgt
      961 tataaggaat ccgatgtcct gtcactagca aacgatgcgt gttgatcata tacggcgtac
     1021 atgtaagcaa ggtaactaag tcttctcctt ctgaaatcgt tagaacagac gtgtcatctg
     1081 gcagtaccac ttgtatattt ttaacttgat aagccaattt ctcccccaaa acagtcaaaa
     1141 taaacgtgtc tccgttttct aaacgatcta attcggtaaa taaccgtcga ttaggtaaac
     1201 cgctgtgagc agagatcact gaatgcgtcg aatttccacc aagcgggaaa gaggttcctt
     1261 gcaagacgcc tgctccattt tcaaggatcc taccattgag ccgatcataa agtgaaatat
     1321 ttaattggat cttaggtata ttgatacttc cgatcagcca ttcctctaat tggctggatg
     1381 ttgtactttc atttctgttc ttttcattga aaggatcagt accaggattg aatccttggt
     1441 cagttaatcg ttggtttttc tcctccattt tctttcgctg cacttcaatt tcagctgcgg
     1501 tccgtttttg tacttgttcg atacgttttt gatcaataaa actatttaaa gaatccacat
     1561 aaaatggata taaagcgatc agtaacccta cgacgataca tattaataaa aacaaacgaa
     1621 acaaaagtcg acgagactgt ttttgcttac tctgcttcac atgtgtcctc ccttgcaagt
     1681 ttttttgttc tttcttttat tatatgggtt caggaaaaaa atagaaaatg aaagccgatg
     1741 aggttgtgaa aaagctgtcc tgcatcaagt aataagtaca gcccaaaaaa atagctactc
     1801 atattttttg ttgggttggg cttattaccg cagatgcaag cttttgaaca ccgtttaagg
     1861 aagaggttgt gaaaactgcg ttatgctttg agtaataaga gcgctagtca gaaaatagct
     1921 tctcatattt tctaggctag tgagcttatt accgagaagc agctgattga acaccgttta
     1981 ccgagaggtc atgaaaaagc tactttgttt cgagtattaa gaaaaattct gtttcaaaac
     2041 aaggagatgc aacaaaactt atgtcgcatc ctctctcctt agaactttca cttatgtttt
     2101 tcttgtaaaa ttcataaata ttttcatgaa ttttctaatt tcttgcctac ctctcgcata
     2161 ggatatatga tgaatttatc taaagtttgc aaaggagttc gacaattgaa aaaatatggc
     2221 ccatttttag caattttttt cattgctttg gcatttctca tgcctcattt attcacacat
     2281 aaactaattt tgggtgctga tgccccattc cattacaatc ggttctatga tgccgcgcaa
     2341 caaattaaat atggggattt ccattatttt ccttcccttt atggattcca gcaaagtggc
     2401 aggatcgtga atgccgttta cggcccattt ttcgcttatt tacaaggatt gatcgtgttg
     2461 cttgcaggta gctggtttca ttatcagatt ctttcaaatt tcattcttta tcttatttca
     2521 ggattttcta tgctgatttt actgagatat gtcaatgttc gaaattgggt aagtgtacca
     2581 gtagccgttt tattcatgag tacgtattct attcaatact ggtctatcaa ccaaggattc
     2641 actagctggg ggacttgttt ttatccttta tgtatgatcc ctattgctga tttcgtcctt
     2701 cataaaaagt tccctgttat caaagtcgct gtctcagtgg gacttatgac acagatccat
     2761 ttactgtctt cgatcatgtt agctttgatg tatatccctt tttatcttta ttactttttt
     2821 aaccagactg aaaaaggaaa agcactgctt caactgatta agtcggtctt gctttatttt
     2881 gttctgacag caaatatttg ggcaggatta gctattgttt acagtgggaa taagattctt
     2941 cctccctttg ttaacagaga aatgagtcaa aaggcgatag atctggatgg cagttattgg
     3001 ctccattacc ctaaggcctt tcctatattg atattatcag gttttttgct ttttattttc
     3061 tttcaacaaa agaacacctt attccaaaaa atcgtgttgt acacaagtct tgttttcttt
     3121 tttctttcta ctagcttgat tccatggacg acattgatcg aaaaaaatgt gccttttatt
     3181 agtttgatcc agtttccatt tcgatttttc gtgccattta cgctattgct tctactttac
     3241 cttgcccttt cactgaacca gtggtctgaa caaaagtggt tccgtctttt aagtatattt
     3301 ggcattctta ttttttcagc acagacgatc cagaacttat accagcatct ggaaaagtgg
     3361 gaaaatgaaa catttgtcag tcgacatact tatctattcg atacgccgga agaagcaagg
     3421 aaaacattct tcagcaaaga tatgtctacc agcttgttcg ttttccaaaa aaccacacct
     3481 gactatctgc caatctataa ggagacaaaa gacaataaat acgaccggta taacgaagaa
     3541 atactagaaa acgaaacaac ttttataaaa acacatccag gcggtctttt gacaatcaag
     3601 tggaaaaaca ctggggacaa aactgttcat atccctgtta tcgtctacga tcggactgtg
     3661 ctacagcaaa atggaaaaac attgactgat tatgaagtaa cagatatcgg gaccccaatc
     3721 gtgaagcagc aaaaaggaat caacgagctc acgcttcatt atcaaacgcc aatctatttc
     3781 tatttcattc tttctcttac tttgattggc tggtttacct tgctatgttt atttatttat
     3841 catagataca agcttttacg tgcttaggca aaagggataa atacatccga tcaaaaaact
     3901 ctccaaacgg tataatcgtt tggagagttt tattttaatc agttttttta tgttatatgt
     3961 tatatttttt attcgttcac atctaattcg atttccaccc cgtagtgatc actgatgatt
     4021 ggactatcga tcccatcaaa aatccgttga tattttttaa cctgcattcc ttcagggacg
     4081 aaaataaaat ctatacgcaa tttttctgta ttttgttccc aaccatctat tttcttttcc
     4141 acagtagctg cttttccttt ttcattcgcg acaacatacg aatcttgaag aagaaggcaa
     4201 ctttctctta cagtataata accttgagag tctactggat tattgaaatc acctaggaaa
     4261 aaaagtggta cgcgagtttc caaaaagtag ttttccaagt ttttccactc aaaataaaag
     4321 ccactttttt tatctgtcca ccaagaaaag tggcagctcg agacaaaaat gtcctgatca
     4381 tctatctttg ttttcccaat caagatcttg cgtgtctgat aatcttcttt cttttgaaat
     4441 tgggagacgg taaggacctg actttccaat gtttttttcg taagcagtgc atttccttct
     4501 tcatatttat cataaccgat gtggctcatt tcccaactcc aaaaatactc ttttccgtgt
     4561 tcctttaaaa gctgaactaa acggtaggca aaattatctt tacggatagg tacttgattc
     4621 tttaccggac agaacttcat tagcttcgca ggttctactt cttcagattc cagtaattgg
     4681 ttgatttctt gtaaagcaat cacttcataa tcttctaaca ggatcttatc tgctaattct
     4741 tgcaattttt tctctggttc tggctcaagc cagctatgcg tgttgagtgt catgaatttc
     4801 attggttttc tccttgtctt catttcgaaa caaaagggtt gtgacaaaat ttttgtcaca
     4861 acctctccag caaatagtgt tctcctgcta actcctcagt aataagctca atggaccagg
     4921 agctattttt tgtttggctg tttttatcac ttggtgcagg gcagcttttt cacgacctct
     4981 ccactaaaca gtattcaaac tgctgcttct cggtaataag cccaaccaaa cgaaaaatag
     5041 gaggagctat ttttgtttgg ctgttcttat gacttgatgc aggacagctt tttcacaacc
     5101 tctccttaca ttttaatgga gccgatcact ttaccagctg tcactgtacc taattgcttg
     5161 atcactactt cttctacttt atcgtttgta aatacgatca tgatcgttgg atctttttct
     5221 tcgttttgga tcacatcaag atccatctca gctaatttcg ttcctgttcc tacttcttgg
     5281 ccttctttga cagcaatctc aaaagctggc tgattcattt ggactgtatc gattcccata
     5341 tggatcaaaa cttcgatacc atctttcgtt tccagcccaa ttgcatgttt gctagggaaa
     5401 atacttgtca cttttccagc gatcggcgca acaacttctc ttgatgttgg aataacagca
     5461 aagccgtcac ccatcatttt ttgtgagaat accggatttt ttacttcaga taaaggaatc
     5521 acttctccag aagctgcgga aactagttct tgttctatac ctaagtattg cttactacct
     5581 gcttgtccat ttcctgtaga aaccatttct ggctctggaa tctctgctcc tgattgcagc
     5641 agatcttcga tatctgattt caagacatct gcttttggtc cataaactgc ttggactcca
     5701 ttgtctttga cgatcaatcc catcgcccct gctcgtttcc aggcttcttc agtccctact
     5761 ttttctcgat catttacact tacgcgtaac cgagtcatac aagcatcgac atctttgata
     5821 ttttcttttc ctcccagcaa atgaatgatc tggaccactt gctgatctgc tgttcctgtt
     5881 ccgctgttag atacaacggt ttcttcactg tcattgtcgt aatttccgtt acgtcccggt
     5941 gtagcaaagt tgaatttttt gatcaagaaa tttgctaaga aatacgtaac aacaccaaaa
     6001 gcgatcacac acaacacgaa gttgataaga tctccaccta gacccgcttt gatagctaac
     6061 ggtgtccgag tcagcaattc gatattccca aatgaatgga cccgcaatgg caagatatct
     6121 gccatcgcaa atgcagcccc ttggatcact gaataaatga catataatgg cacagcagca
     6181 aacataaaca tgaactccaa tggttctgtt acacctgtta gaaagacagc caacgctgct
     6241 gaaaaataca ttgatttata tcttgctttc ttatcaggat cgacattacg atacatcgca
     6301 aaagccattc ccatcaagat acctgaagaa ccaatcattt gtcctacttt gaaacgagcc
     6361 ggcgtccagt tatgcaacac aaactcatat tgcgacatat cccctgcacc tttaagattc
     6421 actaaatcag tggcccaagc caaccataac ggatcttgcc caaatacttg tgtccccgcc
     6481 tgtgcgcctg ataaaatctc atacgatccg ccaagctgtg tatagttgat aggaatcgtc
     6541 agcatatgat gcaatccaaa tggcaatagt aaacgttcta atgttccaaa taaaaacggt
     6601 gctagaatcg gtgcgctttc ttgtgattct gcaatccata aaccaaaatt attgattcca
     6661 gcctgtacgt ttggccacac cacagcaaga atcaatgcca cgattgttga ccataagata
     6721 acaacaaacg gaacaaagcg ctttccattg aaaaatgaca aagcatccgg caattttcta
     6781 taattatagt acttattata agccattgcc ccgacaaatc cagcgatgat ccctacgaat
     6841 actcccatat tcaaagctgg tgcttccaat acacttgtaa aaaatccttt aaccatgatc
     6901 ttcgtaccga acagagtgtg ggtaaatgca tcttcattcg caagcatgtc acttgtgaca
     6961 ccaaagatag ccccagtgat ccgattgatt aaaataaatg agatcccagc tgcaaatgct
     7021 ccgcctgctc tttcttttgc ccaacttcct cctattgcta aagcaaataa aatatgaaga
     7081 ttaccaataa ttgcccaacc aatattttca attactccgc ccgttgtgac aagcggcgtc
     7141 caatcaggat tgatcaaggg aattgatttc cctatactga tcatcaaccc agctgccggc
     7201 ataactgcta ccacaaccat taaagccttt ccaaattttt gccaaaactc aaaactaaat
     7261 atctttttca ttccgtttag ctcctttacg caatcggttt cgttaaacgt attatagcgt
     7321 gcgttttctt ttttgtaaat gctttatttt ttatttttct gtctatacca ttctataaaa
     7381 cctataatac gtgtgttccc ttctataatt ttctcctaaa aatttatttt tttaagcttt
     7441 tttctatgaa atattttctt ttgtctattg acttgtgcaa tcggttgcgt ttattatgaa
     7501 cgtataaaac agctcattag gaggagaaaa atgaaacaga tcaaacgact atttgctatt
     7561 gatccatgga aaatcagcac gacacaatta gataaaaaaa atcttcgact gcaagaatct
     7621 ttaacaagta ttggaaacgg ttatatgggg atgcgcggga actttgaaga aacttactca
     7681 ggggaccacc atcaaggtac ttatttggcg ggtgtctggt atcccgataa gacacgtgtc
     7741 ggctggtgga aaaatggtta tccagaatac tttggaaaag tgatcaacgc cttgaacttt
     7801 atcgcgatag atatttcgat caacgatcag ctgatcgact tggcttcttt ggaaccagaa
     7861 gacttttact gggaattaga tatgaaaaat ggtgtattat ctcgtacatt cacaatcact
     7921 acttctacta ataaagtacg catttccttc gaacgttttc tgagcattgt caaaaaagaa
     7981 tcagcttata tctatttaac tatagaaatg cttgaaggta gcggaacagt caaactcgta
     8041 tcaaaattgg atggaaatgt tcaaaacgaa gacagcaact atgatgaaca tttttggaat
     8101 gagattgatc gtggaactat agaagaaatc ggctatttga cgactaaaac tattccaaac
     8161 aactttggga ttgaacaatt tactgttact gcagcaatgc gccatttcgt taatggaaaa
     8221 tcagtcatcc ctgactatca cgaagatact ttagcattac atggttgctt gtctgcagaa
     8281 ttatctcaag gtgagacatg gtcagtggaa aaagaaatta tcgttcttac tagtagagat
     8341 attccagaag cgcagcaagc agaaaaagct gtctcagaat taacgaacca gacaaacaat
     8401 tatatccaag caaaagaaga gcaaacagcg gcttgggcag aacgatggaa gcttgccgat
     8461 gtggtcatcg aaggagacga agaagcacaa caaggtattc gattcaattt gttccaacta
     8521 ttctctactt actacggcga agatgaacga ttgaatatcg gccccaaagg attcacagga
     8581 gaaaaatacg gcggagccac ttactgggat acagaagcgt atgctgtccc tctttatctt
     8641 gctttagcca aacctgaagt aactaagaat ctgctgaaat atcggcataa tcaactgccg
     8701 caagcaatcc acaacgctca gcaacaagga ttaaaaggcg cgctttatcc tatggtcacc
     8761 ttcactggtg tcgaatgcca taacgagtgg gaaatcacat tcgaggagat tcaccgaaat
     8821 ggcgcgattg cctatgcaat ctacaattat acgaattaca ccggcgatac ggaatatttg
     8881 aaaaatgaag gactggaagt tttagcagaa atcgcacgct tctgggcaga ccgtgtccat
     8941 ttttcaaaac gagcaaataa atacatgatc cacggtgtga ccggcccaaa cgaatatgag
     9001 aacaatatca ataacaattg gtatacaaat acgatcgcag cttgggtctt gcgttacacg
     9061 cgagaaaatt atttaactta tcaaaaagaa gctgctatca ctatcagcga agaagaacta
     9121 gccaaatgga aagatatcgc agagaacatg tacttcccag ttgacgaaga attaggaatc
     9181 tttgtccagc atgacacatt cttagataaa gatctcatgc ctgtatccga tattcccaca
     9241 agcgatcttc ctctgaatca gcattggtct tgggacaaaa tccttagatc ttgcttcatc
     9301 aagcaggcag atgtactaca ggggatttat ttcttcaatg atacttttac aaaagaagaa
     9361 aagcaaaaaa actttgattt ctatgaacca atgactgtcc atgagtcttc cctttcgcca
     9421 agtatccatt cgattttagc agcagaatta ggaatggaaa gcaaagctgt agaaatgtac
     9481 cagcgaacag ctcgcttgga tttggataat tacaataacg acacagaaga cggcttgcac
     9541 atcacttcca tgactggtag ctggttgtcg attgtccaag gatttgctca aatgaaaact
     9601 gcccatgatc agttgagatt cgcaccattt ctgccaaaaa cttggaaagc ttattctttc
     9661 catatcaatt atcgcggacg tttattgttc atctcagtca cagatgaaca agttactttc
     9721 gagttattag aaggttctcc tctagaaatt tacgtctatg aacagtctta ttctttagcg
     9781 gatcgtctag aaataacgct aagaaaggag gaagcaaatg tttaaagggg tattgtttga
     9841 tttagacggt gtcattaccg atactgctga attccattat cgtgcttggc gaaagcttgg
     9901 tcaggaaatc ggcattacga tcgaccacac attcaacgaa cagctaaaag gcgtcagccg
     9961 agaagactca ctctctttgc ttttagctta tggcggaaaa gaacactctt tttcaaagga
    10021 agaatttgca gaattagcga aaagaaaaaa cgattattat ttagagatga tccagacgat
    10081 cgaaccaaaa gatgtcttcc ccggggtcgt gcctttactg gattctttaa aagaagaaaa
    10141 aatcaagatt gctcttgctt ctgcaagtaa aaacgggcca ttcctacttg aaaaaatggg
    10201 tcttacacct tactttgatg ctattgccga cccggcagaa gcaacaaacg gaaaacctgc
    10261 gccagatatc ttcctccttg cagcaaaagc tgtcggacta aaagcagaag aatgtatcgg
    10321 gatcgaagac gcgcaagccg gtatccaagc catcctctca agtggcgctc aaccaattgg
    10381 cgtgggacgt gctgaagacc ttggagagga gatcccgctt gtccctgata cgacttttct
    10441 tacgatcgat tacttgaaag aaaagtggca tgaccatgga taatccagag atctccgtcg
    10501 taccagttcc agagactgaa ataaagaaaa tcacattgaa gaacgactac ttagaagtcg
    10561 ttcttctcaa ttacggtgcc cgcctgcacc aaatcttcgc accagacaaa gaaggaaaat
    10621 cagaaaatgt tttattgtct tacgatcgtt tcgaagatgt tctaacagac aaaagctttt
    10681 ttggagcaac tgtcggacct gtagccggaa ggatccggga tgcttcttgg ggtgagcata
    10741 gattggagaa aaactgcgga tcacaccata tccacggtgg cacgaaaggc tggtctttcc
    10801 aattttggga agtagaagtt ttcaaaactc catcatcaat aggtgtggtc ttttacttaa
    10861 aagatgaatt ttctacctat ccaggaccaa tcactgctac gatcacttac cgtttaacaa
    10921 aaaacgaatt agagatgaca acctctgcta gtagccttgt tgaaaccatc tgcaatccga
    10981 ccaaccatgc ctacttcaac ctttcaggaa atggaacaag agacatctat gaacatcagt
    11041 taacggtctt tttagatggt gtgcttgaat tagatcaaga aaaactgcct actggaaatt
    11101 ggacaaaaaa agaaaaactg ccaatcgact ttagaaaatc cccaacactg caagagatcc
    11161 ttgcatgtta tccagatgga ctagatgatg tatttctttt gcatcatcct aggctttcca
    11221 aaacttcctt acaattattc gagaagcatt ctggtcgcca aatgactata gcaacttcta
    11281 ataaaagtat ggtattattt tctacgactg gattcgaagc tgatttctct gtcaatggaa
    11341 aacagatgca ttcaaactac ggattagcaa tcgaaccgca agaaatccct gatatcgttc
    11401 atttccccaa atttggatcg atcaacctcc atcctggtca agaacggatc agtcagacga
    11461 tttatcggtt ctctgcacaa taacaagaga aaggtgtttt tatcatggct attaccgtaa
    11521 aagatgtggc gaaaaaagcc ggtgttgcca cctcgaccgt ctctcgtgtc atcaacgatc
    11581 atcctagtat ttccgagaca acaaagaaga aagtccgaaa aattatggat gaactaggtt
    11641 atgttcctaa catgactgcc cgcaatctag gaaaacgcat ttccagtgcc atcggcgtaa
    11701 tcttaccccc tcttgattca aaagagcgga tcggtaaccc attttatctt gagatcatgg
    11761 aagcaatcaa cgaagaagcg cggaattatg atatgactac agcaatcgct actgctaaaa
    11821 attttgaatt gctgttagag aacgtccagc gtatgcattt acaaaaacaa gtagatggtt
    11881 ttattctagt gtattcagat agtcaagata ctgtcattga ttatttatac caaaaccaca
    11941 tccctttcac tttgatcgga cagccttatc atcatgagaa cgaaatcgtt tatgtagata
    12001 atgataacca gcttctaggt aaacaagcaa cagaattttt gatccagaat ggacataaga
    12061 atatcctgtt tgtgacaaac acgactcatg aaagtttgta tttcgaacga tatttcggtt
    12121 atcaaaaagc aatgatgatg gctggtcttc ctgcgttatc cagtgtagta ctagagcatc
    12181 cggaggatta tctgtccttt gagaaaacgt tgaaagaaaa cgaagccaca gcattggtgg
    12241 tcattgacga tatcttcgcc cttcgcacga tgcagttggc gcaaatgtat ggctatgtca
    12301 ttccagagac actctccgtc attagcttca acaactcgat cttctcaaca ttaacacacc
    12361 cttaccttac aagtatcgat atcgatatct ccgaattagg acgtgtcgct atgcaaaagc
    12421 tgcgcgaatt gatccatgaa gaattgagca gtggcgtacg tttggtcatc cctcatcgct
    12481 tgatcaaaag agagacagtc gttcctttag aaaacccata ctaaatagct gactcactaa
    12541 atacgctgac catttatcct atggtcagct ttttatgtaa aagaagatac tacttctaac
    12601 acattgttta tctgtaaaaa agagcgtggg acaaaagtaa agaacacttt tgtctcacgc
    12661 tctaaacacg tataaacggc ggaagcagaa gcaactcctt cggaaataag ctgaaattca
    12721 caaaaattta aaaagcaatt ttcttgagtt tcttcttatt tcttggagtt aaacgcttct
    12781 gtcccagcct cttttttcct tccttcaatt tttttacacg tcgacgattc aataaaaaac
    12841 cgcctaatat tgtaaagaca ggtgcaagaa tcgagaaaaa ggcgaatggc aagtaatgca
    12901 acgcgctaac tttcatcgtt cccataatga atgtgccgct gactccccac ggtacgagag
    12961 aattgacggt cgcacctgaa tccgctagtg ttcgtgtcaa ataggttttt gataagccaa
    13021 cgtcatcaaa agaacgcttg aatgtttctc ctggaagaat gatggacaga tactgttctc
    13081 caacgatcag attgattccg atacagctca aggcagtaaa cccgactaaa cgagaaggtc
    13141 ggtccatctt ttcttttaat tcttgaacga tggtatcaac gatcagatat ttgatcagta
    13201 acccacctaa tgccaatgca agtaaaatca aactagcaga acctaacata ctcatgatcc
    13261 cgcctcgaga aagcagttca tctagctttg gatcaggtgt atttgcgaca taaccattca
    13321 tcaagatgtc tgctgctttt ccgaccgtca aacttttctc atggataaaa gaaagaacga
    13381 gagcagctgt cgatcccgct agtaatgtag ggatagccgg aatttttttg attgcccccc
    13441 caaataaaat aactagtgga atcaatgtcc aaggagagat ccaaaagctc gctttcatgt
    13501 tttggatcat ttcattgata ctagctagat cggctgaatg actgttatgt cctaatatcg
    13561 tataaaaaat caacgaaagg acgaatgctg ggaaatccgt ataacgcata ccagcgatat
    13621 gttcgaatag attaactcct ccaatacccg ctgccaagtt ggtcgtatct gataaaggcg
    13681 agcagttatt ccctaaaaag gcaccggaaa cgactgcgcc tgtagtcatt gcatcattga
    13741 atccaagtaa atgaccgatc cccaaaaaag caattccaat cgtcgaaatc gttgtaaatg
    13801 aactgccgac agtcactccg acaattgcac aaacaagaaa tgctgtcggt aaaaagaaac
    13861 gcacagaaac aagtttaaat ccataaacca taatcgtagg gatggttcca gataaaatcc
    13921 atgaagcaac taagacacca atcaaaagaa aaatcaggat tggaatgatc cctggagtga
    13981 ttcctttgat gatcccgtca tggatctcat cccatgtgaa ctttttaaat ctgccataaa
    14041 acaacaaaca catgaaagct gcaaggatcg ggatatgtgg cgagagctgg aatccgatga
    14101 tcagtactcc taggagtgcc aacaacacga tcaatacagc gatactttct tttaaagaaa
    14161 tatttttatt catcgtcgat ctcctatttc aaatgaaaag gccctgccat gaaaaaacta
    14221 ttcacttggc aggacctcct actaaatcag cgacaaaacg tcggctgaaa gacttatttt
    14281 tttatttttc ttctaaactt ttttctacct caatccccca agaatctttc ttgaagtgat
    14341 tgatgatcaa tggaataacg aacatgacca ctgtgatagc tgctactaat aatgcatcac
    14401 tcaatgtcgc tgtacctaat gtagcaaata cgacaacgat gatagagaag atcagcatgc
    14461 agctgactac ccaagctaat ccgtttccgt ttttaccaat tcggtaagga cgttcgaatt
    14521 ctggatgttt cttacgcatt ttaagcaatg aaacagcaat caaaatgtac acgatacaat
    14581 aaataacagt tgtagcattt gtaagtgtca agaatacagc acttacgtca tccattacac
    14641 cataaagcaa agcaaataat gaaataacga ttgattgtgt tagaacgaca tttctagata
    14701 cgccgtattt gttttcttta tggaatccga attttggtgg aaggaatcct tcacgagcta
    14761 cttggatgat tgtttttgat ggtccagtaa cccaagctga taattgtaaa agcacaccaa
    14821 taaataccat gaagctgaag atatttccga tcacttctgg taagcctagg atttgacagt
    14881 caatcaagat aggctgcgtg atatttgcta attccatttt tccatctggt acgacatttg
    14941 ctacaagcat cgcattgatg acattcaata aaactaatcc gatcaaagcg ataaatacgc
    15001 cttttgtata attttttgtt gcgtctttca aacgaggcat gtaaacagaa ctcatttcga
    15061 tcccaacaaa aataaatgtg ataccagcta agtatttcaa tgaatcaata tgttccaagt
    15121 cagggaaagc ttttgaccat gaaaagtcac ctagatagcc gtttgagact agtccgactt
    15181 tgaaggctgc caaaacacct aaaacgaaca tgatgactac tgggatatat acccctagcc
    15241 atacaccgat gttcccgccg acttttgcca tatcgaattt caagttcaag atcgtgatga
    15301 tccagtagat aactaaaata caacctaaaa cgaaccagtg attattgcca agttctacat
    15361 taccaaatgt gtttcctaac aatggtccta aagtagaagc gaccattacc atacctggga
    15421 acatttgcac ccataatagc catgcaacga caaatcccca tttgctgccc agtgctgttt
    15481 ttacccataa ctgaggaccg ccttcttgag gaagcatcgt ggaaagctca ccggaaacca
    15541 ttgatatcgg accggcaaaa aacaaaactg caaaaattga ataaaaaatc aatgtccaac
    15601 cgactgcggc taacgtagga atactccgaa ccgttgcaca cagtgccatt gtcagaccga
    15661 taaaggtccc aagacccatt ttacttactt cagatttact caccgttgac actctccttg
    15721 attttttgga taaaataacg gtgtctttga agtagtttca gcaataaacg aaacaattca
    15781 gcgaatattt gaggggattc tttgagttta ttgcttgaag ggtttcttca aagacaacct
    15841 caaaacaaag ggatcgaaga gcttaggtct ccccttgctc ttcagatcca aacatgcgtc
    15901 agaaacagtt agtattcaag ctgttttcta acatgattac cttgcttatt ttgcttcgct
    15961 tgccaataat tggtctgcgt agattttttc caatttttct tgaagagctg ctttgatttt
    16021 ttcagcatat tcttcaaagt gttcttcttt gttcatgtat ggtgtcatta cgctggcacg
    16081 caatacagtt acttttccgg cacggttcca ttcttcatct gagaatccta gttggttcac
    16141 aaattgtaat gggctgttgc catagtctgg gatagcaaag tcagtatgtg aagttaagaa
    16201 ctcattaccg taaatgcttc ctttcacgta tgaagaataa tcatatacgt catggttcaa
    16261 tttattcatt gcaactaagt catcgttgcc tttttctttg aatacatagt ctaccatatt
    16321 gaaatctgga taagttaatg gatgaacttc gatttctttg tctcctactt taaatgacaa
    16381 gtcattcaag aagttgtaga aacgatgtgc accttcgatt gatgcaccca ttaatttacc
    16441 atatcctgtg acattcaaag gtaagacatg gtgtgctgcc caaacgctgg ctgctgttgc
    16501 ccctgctttt gaaccttcca agatataagc cccaagtaat gctgggatat ctgcgccttt
    16561 ttcaaataca tatgtcgcaa agtaagagat aacgtttctc atgcggatat ctttgatgac
    16621 gataccaccg gcagaatatg gaacatagcc cattttatgt gggtcaatcg ttacagattc
    16681 tgcttcttcg attgctttat atgcactgtg tacttcttct aagatataat ctttgttttc
    16741 tgtaaagaca ttgtatttgt aatgaacatc ttttaaatct tcaaatggaa tgaagttgtt
    16801 gtcttcgtct aagaaaatcg cacggccgta tccgccataa gcagcatcta cgtgtaagta
    16861 gaagtaaata ccgtcttttt ctaatacgcg acgcaatgca acgattttat cgataccgtc
    16921 gattgctcct tcttctgttg atcctacaac accgactaca cctaggattg gtgttttttc
    16981 agctgctaga ccacgaacga ttttttcaag ttcgttgatg tccatgcgat agttgtggtc
    17041 aactggcact ggaatcactt ggtctaaacc gataccgatg atgtcggcag cttttagcca
    17101 tgaatagtgt ttagtttgtg gaaccaacca ttttcctaat ttttctaaat gttttccgct
    17161 acgtgctgag tgagctttga tttcgtcgat tttttctggg acgctgtcta acagattcat
    17221 gatttcttct gttgacaagt tcattaattc ccaatcgctt tttccagcaa ctagttcagg
    17281 tgtcacttct ttcattgcaa gcggcaatga tttgatgttg cgggcatacc aaagtccttc
    17341 taagtttgct aaagaaccat cagcaacgat gtggccccag ccatctttat agctcattaa
    17401 ttttgcaaat tccattccta cttcttcttc catttggctt gttgcaggag aagattcata
    17461 ggcaacgtta ttaccattcc atagcatagc aaaattgtac gctagtaaag atggcatcaa
    17521 tgtttcagag ttcatatgac cccagtaacg tccggcatta tgccaaggaa cggaatgggt
    17581 acgcatccgc gctgaaattt ctgatagaac atcctttgtt ttattcacag tgtgttcaaa
    17641 actagcactg cttttttctt ctggcgtaat aataggcatg tcttgaggca tgtagttttg
    17701 acgccagcct aaatgttcat ccaccaattc attcaacaaa gctttataga tttggccgtt
    17761 ctcagctttg tccccaatga atagggcatt taggtttaga tctttcgaca atgattcact
    17821 catagtgaaa ccctcctaaa aaaatattta aattttgtcg agccctacat tacacctgtt
    17881 cttctattct gtaaactaag ttttggcctg atttttaatc atattttaat atgtatcaat
    17941 tatccgaatt gttcacactt ttgaaataat taaaaaaaac gagggaattt acaaatgtaa
    18001 actccctcgc aaagattgta ttaacgacaa ccagcgttct attttaggat gggtttcaaa
    18061 attggaatgt tgtaatagta tttccctttt tcaaggtaaa aacttactaa attctaatca
    18121 attactttgg ccaaaaagta atttttctta ccttttcgaa taaccacaaa cttaccatcg
    18181 aattcatcgg atggatttat gacaaaattt aaatcggtaa cgcggtcacc gttaatactt
    18241 atagctccgt ttgaaacatc ttcacgtgct tgacgtttag atggttcaat ttttgtggaa
    18301 acaagcagtt ccacgatatt ttcaggtgtg cttgaaattt caacgttcgg cattttaccg
    18361 aatccttgcg cgatttcttc cgcatttagt tctttaatat ttccagagaa caatgcttgc
    18421 gttatttttt gcgcttcttt caagtcttct tcactatgca caaatcttgt aacttcttct
    18481 gccaaacggc gttgtgcttc acgtttctca ggttctgtct ctactttttt cgctaagtct
    18541 tcgatttctt cttgagacaa gaaagtaaag aatttcaagt atttcactac atcgcgatca
    18601 tcttgattca accagaattg gtagaactca aatggtgaag ttttcttcgg atcaagccaa
    18661 acggcaccgc ctgcagtttt tccgaatttc gttccgtcag ccttcagcat caatgggatc
    18721 gttaaaccga acgcttctgc ttctggtcct tctaattttc ggattaggtc taatccagct
    18781 gtgatatttc cccattggtc tgctccaccg atttgcaatt gcacatcgta tgttttatgc
    18841 agatgcaaaa agtcgataga ttgcaggatt tggtaagtaa actctgtaaa tgagattcct
    18901 acttccaaac ggctggcaac gatatctttt gctaacatcg tgttgatgtt gaagttttta
    18961 ccgtagtctc tcaaaaattc aagtaaagag atttttgaca accagtcgta gttgttcaca
    19021 aatgtgatat ttgcatcttt accaaacaat tttctcattt gattggaaag tgcgtccacg
    19081 ttatgttgca cttgttccat cgtttgcaac acacgttctg ttttgcggcc gcttgggtcg
    19141 ccgatcgttc ctgttccgcc gccaatcaga atatatggat gatggcctgc caattggaat
    19201 cttttcatca tcataaatgg aatcaaatgt ccgatatgca tcgaatcacc agttggatca
    19261 acgccgcaat aaagtgaaat gctcttttct tcaacgagct cgcgaagtct ttcttcgttt
    19321 gtttgctgat taatggcgtc gcgccaagtt aattcatcaa taatattcat tttactgacc
    19381 tccgtgtagt ttttttatga aagcaggaac ctgctagcat atgtaattaa ttatttcttc
    19441 aggataggat aggaaataaa aaaagtccct tggcatataa gccaagggac gaaatctcgc
    19501 ggtaccaccc aatttgtatg tctagatatc caacatacct ctcgaacatt taacgctgtc
    19561 gcgtggcaat cactgccaaa gactcctgaa atgtaattcg ctttaaagca tgtactggtt
    19621 tgcagcgacc accagctttc tgaaacattg gctttaacaa ctacttcgtt tcgatcttcg
    19681 tcttgttatt attaatatgt gtctatcata gagcgcaact ttttctttgt caacagaaaa
    19741 aggatatttt ttttaaattc ctcatttttt cttttttgaa tccgctctaa ttccgaacat
    19801 tttattttca attattgtta aaagaaataa ctttttctgt attttttctg caatttatcg
    19861 agaagtcact ttactttgcc tcttattctt tcttcgttac aataaggaat gggacaagta
    19921 aaaaaatgaa aaagcaaggg acgaggtata tggaaaaaaa gcaaaaaatt attttaggag
    19981 ccacttctgc tttaactatc gttattttaa ttctaagttt gttttttgtc atccgatcat
    20041 ctacaaaaaa agaaccaatc attcctgaaa aaaaaataac agaaaaagca aaagaaccga
    20101 cagatgataa gcaacaacta gttactcaag caaaaaatct ggctcaaagc tacgattatg
    20161 accaagcgat tgcgttattg gaaaaagata gtaagaacgg atctactgaa acacaacagc
    20221 ttcttcaaac actaaaaaag gagaaagaac aactgatcga ctggtctgat cctactcaga
    20281 tctctcatgt ctttttccac agcttgatcg tggacccgca aaaagccttc cactctcaac
    20341 aggcacaagg atacaaagat tatatggtga ctgttgaaga attcaaccgt tcgatcgaac
    20401 aactttatca aaatgatttt gttttagtta atttgaatga tttgatccaa aaagacgaac
    20461 aaggaa
//
LOCUS       DAFELK010000054        19975 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFELK010000054
VERSION     DAFELK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.056"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            299..1960
                     /locus_tag="LP433_002209"
     CDS             299..1960
                     /locus_tag="LP433_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2006344.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2377)
                     /locus_tag="LP433_002210"
     CDS             complement(2030..2377)
                     /locus_tag="LP433_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBL2006345.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2461..3402
                     /locus_tag="LP433_002211"
     CDS             2461..3402
                     /locus_tag="LP433_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2006346.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3403..4446
                     /locus_tag="LP433_002212"
     CDS             3403..4446
                     /locus_tag="LP433_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2006347.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4452..5522
                     /locus_tag="LP433_002213"
     CDS             4452..5522
                     /locus_tag="LP433_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006348.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5512..6465
                     /locus_tag="LP433_002214"
     CDS             5512..6465
                     /locus_tag="LP433_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2006349.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6477..7487
                     /locus_tag="LP433_002215"
     CDS             6477..7487
                     /locus_tag="LP433_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2006350.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7772..8593)
                     /locus_tag="LP433_002216"
     CDS             complement(7772..8593)
                     /locus_tag="LP433_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL2006351.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8690..8968)
                     /locus_tag="LP433_002217"
     CDS             complement(8690..8968)
                     /locus_tag="LP433_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006352.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9236..11245
                     /gene="metG"
                     /locus_tag="LP433_002218"
     CDS             9236..11245
                     /gene="metG"
                     /locus_tag="LP433_002218"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBL2006353.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11724..12311)
                     /locus_tag="LP433_002219"
     CDS             complement(11724..12311)
                     /locus_tag="LP433_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006354.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12486..13808
                     /locus_tag="LP433_002220"
     CDS             12486..13808
                     /locus_tag="LP433_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2006355.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13963..14739
                     /locus_tag="LP433_002221"
     CDS             13963..14739
                     /locus_tag="LP433_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL2006356.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14732..15301
                     /gene="rnmV"
                     /locus_tag="LP433_002222"
     CDS             14732..15301
                     /gene="rnmV"
                     /locus_tag="LP433_002222"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBL2006357.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15294..16178
                     /gene="rsmA"
                     /locus_tag="LP433_002223"
     CDS             15294..16178
                     /gene="rsmA"
                     /locus_tag="LP433_002223"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBL2006358.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16629..17258
                     /locus_tag="LP433_002224"
     CDS             16629..17258
                     /locus_tag="LP433_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006359.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="LP433_002225"
     CDS             complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="LP433_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBL2006360.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18700..19122
                     /gene="mgsA"
                     /locus_tag="LP433_002226"
     CDS             18700..19122
                     /gene="mgsA"
                     /locus_tag="LP433_002226"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBL2006361.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19445..>19975
                     /locus_tag="LP433_002227"
     CDS             19445..>19975
                     /locus_tag="LP433_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL2006362.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHA"
BASE COUNT         6499 a         3589 c         4077 g         5810 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgaggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt tatttttggt
     2401 tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg ggaaacatta
     2461 gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat cacgctttgg
     2521 ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc atatacgaat
     2581 caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg tttggataaa
     2641 ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga ttttggaatt
     2701 tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat cggaccatcc
     2761 ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat tttaggaacg
     2821 atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt agcgatatta
     2881 ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt tgcaatcaaa
     2941 ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt accaacaatt
     3001 gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga aatggtggaa
     3061 gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg ttgggaaatc
     3121 gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt aggaccgtta
     3181 gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat tcctggtatc
     3241 ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat ggctgtaacg
     3301 atcctttact catttatgct gatttttgtt attttgatcg tggatctatt gtacggtcta
     3361 gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat gataccaaag
     3421 cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca aaaaaatacc
     3481 gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga ttcatggcgc
     3541 cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt catcattttg
     3601 atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa cgtggcttat
     3661 atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg aaaagcaatg
     3721 gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa cgtaaatttc
     3781 tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat gggaatgaga
     3841 atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg tgtagcttac
     3901 gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg ttttttggaa
     3961 atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt ttttgaacca
     4021 ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat ggcacgtatc
     4081 gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg attgacatta
     4141 ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc tagtgtcatt
     4201 attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt tttaagcttt
     4261 atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag cgaagggtac
     4321 aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt atcggttatc
     4381 atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc taaaatgaaa
     4441 gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct tttgatacgt
     4501 atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa ggagaaacat
     4561 tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc atcatgcgct
     4621 tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt aacgatatcg
     4681 ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg atgattttcc
     4741 aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc gctgagtccc
     4801 ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta gaattgctta
     4861 aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat cagttctcag
     4921 gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg gaaatcctga
     4981 ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt ttggagctgc
     5041 tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat gaccttggtg
     5101 tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc gttgaagttg
     5161 gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga ctgcttggtt
     5221 caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt tctccaccgg
     5281 atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc gcgatgaaaa
     5341 tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag gcagcaactt
     5401 ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa cgtcgctggg
     5461 ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct gatgccaaat
     5521 aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa gaatgaagta
     5581 catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg tttagttgga
     5641 gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa tgaacctact
     5701 gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa aaaaggtttg
     5761 acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc gttgaatcct
     5821 cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact agctaaatca
     5881 tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt gaatccaagc
     5941 cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat tggtattgca
     6001 cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc tgcactagat
     6061 gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga acatcaattg
     6121 acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga ccgaatcggt
     6181 gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta taatcacggt
     6241 gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc agaccatgag
     6301 agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt acgtcaactt
     6361 cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc atattacgca
     6421 aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg acatagatgc
     6481 taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa ttgattcgta
     6541 cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag aaaagttggc
     6601 aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa gaatacccat
     6661 tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg gatcgggctt
     6721 ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa aaaagtatgt
     6781 ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat ggctacttaa
     6841 agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt gaaggatcga
     6901 ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca ctactttgtg
     6961 atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc tatcatccga
     7021 agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt caccagacag
     7081 aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc gctcaccata
     7141 gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa gtaatggatc
     7201 tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct gggaaattgg
     7261 tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca catgctgatt
     7321 tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc caatggtata
     7381 ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc gtaagaaaga
     7441 gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa atgaatgaaa
     7501 ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt ttgtttctag
     7561 gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac aatagcagaa
     7621 aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt ttacgaatac
     7681 atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt tttttcttga
     7741 atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc ttgagctgat
     7801 agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg aaatattgga
     7861 gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct aagaatttag
     7921 caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt agaacttgcg
     7981 gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt tgactatggt
     8041 caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc gagatagcca
     8101 cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac cagcgtactt
     8161 ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag tagctgactg
     8221 tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt tgctcaatat
     8281 tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg ctttctccag
     8341 ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga taaggatgcc
     8401 cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag cacatcagta
     8461 cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt tgataccagt
     8521 taagaaattc ttcttcactt gctttatgtt cataatataa tttttcttct tctttagaag
     8581 caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc ttattgtagc
     8641 agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt taaatatgaa
     8701 aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc aatactttat
     8761 accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca atgataaaac
     8821 gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta aaataaccat
     8881 acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa gcaatactaa
     8941 gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa gatagatagt
     9001 ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag atatgaaaca
     9061 aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat tgaacgtaga
     9121 tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat gcttttttta
     9181 tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga gccccgtggc
     9241 agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca aacttcatat
     9301 cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac ggttgatggg
     9361 ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg aaacaaaagc
     9421 agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg atgtcaagaa
     9481 attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag atgattacca
     9541 taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata tttacttagg
     9601 tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa cacaacttgc
     9661 agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa gtggacacga
     9721 agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg cagaccgtct
     9781 attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta aaaacgaaat
     9841 gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa caacttttac
     9901 ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga tcgatgcatt
     9961 atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat tcgaaaaata
    10021 ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata cgatctattg
    10081 gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg ggcatggctg
    10141 gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt atcctgaaat
    10201 gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg ctgttccgtt
    10261 tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt atgatctggc
    10321 aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat attgtgatgg
    10381 actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt ctacgacggc
    10441 tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca atacagcatt
    10501 ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa cagaaccatg
    10561 ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga tccatttagc
    10621 tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa cgccagagaa
    10681 gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat tacactttgg
    10741 cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc cacgtttaga
    10801 tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc aaacaaacga
    10861 agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag aaaaacaaat
    10921 caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca actgtcaaaa
    10981 agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca gccaagaccg
    11041 tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga tcgggaaaaa
    11101 agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca gtcaaggaat
    11161 gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac caaaatccat
    11221 gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag ttgtgtcata
    11281 cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt acttgaagcc
    11341 aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa gaagtacgag
    11401 cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa cagaaaaaaa
    11461 gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct tttttattgt
    11521 ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta tatctaacag
    11581 tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta
    11641 tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt
    11701 ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc
    11761 aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa
    11821 atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc
    11881 aaccctaaaa gcaaggagcc agctataaac caatgattat cccaatgcat gacttcacta
    11941 agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag
    12001 ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata
    12061 ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct
    12121 ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt
    12181 gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt
    12241 tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc
    12301 ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa
    12361 aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg
    12421 taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga
    12481 tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta
    12541 tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc
    12601 agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg
    12661 gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata
    12721 ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt
    12781 actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat
    12841 tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag
    12901 ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta
    12961 aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg
    13021 tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg
    13081 cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg
    13141 aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa
    13201 cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg
    13261 ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa
    13321 agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa
    13381 ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc
    13441 tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag
    13501 tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg
    13561 tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc
    13621 cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc
    13681 tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg
    13741 gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag
    13801 aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg
    13861 tgctttttct atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt
    13921 agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat
    13981 acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa
    14041 gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct
    14101 ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag
    14161 gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag
    14221 gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc
    14281 caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt
    14341 attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga
    14401 gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt
    14461 gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc
    14521 caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat
    14581 ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta
    14641 gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca
    14701 aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat
    14761 agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat
    14821 agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga
    14881 gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat
    14941 cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc
    15001 aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt
    15061 gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga
    15121 ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg
    15181 tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt
    15241 tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg
    15301 aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt
    15361 catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg
    15421 tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg
    15481 cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc
    15541 gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc
    15601 aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc
    15661 cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc
    15721 ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc
    15781 gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt
    15841 atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg
    15901 tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg
    15961 aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga
    16021 ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct
    16081 tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg
    16141 ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt
    16201 tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg
    16261 tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    16321 aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct
    16381 catgtttttg agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg
    16441 aacaaggaga tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa
    16501 ttcttatact tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga
    16561 cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga
    16621 gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga
    16681 tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt
    16741 tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg
    16801 ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag
    16861 cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta
    16921 tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg
    16981 tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg
    17041 gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg
    17101 ggattggtgg gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa
    17161 cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag
    17221 agtcgattca agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa
    17281 ctctcatcta gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag
    17341 ctgcaccaac atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact
    17401 tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt
    17461 tcgcctggtt tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt
    17521 tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact
    17581 acggcttcag gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata
    17641 ccgaagataa cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca
    17701 ggaatacgaa gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta
    17761 aagaagttca tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca
    17821 taaacttctt tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg
    17881 tcagccatag tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga
    17941 cgctggtgaa gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt
    18001 gataatggct catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc
    18061 acacgttggc gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga
    18121 cctaagatct ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt
    18181 aatttcaagc caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt
    18241 tggaaaacca tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg
    18301 atatttagtt ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac
    18361 tttccacaac cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta
    18421 aaatcagtta cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc
    18481 atttctacca taatacgttc cacactttct tttttagttt tattaactat ttaaagtata
    18541 aatgaaagcg ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc
    18601 aatgtgctag ttttaagctt taataaatat ccataagaaa taaaaactga tacactggag
    18661 taaataagta tgttaacaat atcaaaagga gtgtctctta tgaaaatcgc tttgatcgct
    18721 catgaccgaa aaaaacctat gatggtgaaa ttagcaacag cgtataaaac aatattggaa
    18781 aaacatgaac tttttgctac cgggacgact gggcagagga tcacggaagc aaccggcttg
    18841 ccgatccatc ggtttaaatc cggaccgtta ggcggggatc agcaaattgg agccatgatt
    18901 tcggaggatc agttagattt ggtgattttt cttcgagacc cgctggctgc acagccccat
    18961 gaaccagatg taacagcact tatccgttta tctgatgtct atgagattcc gttagctacg
    19021 aatatcggaa cagctgaggt gctactaaga ggactggaag ccggcttcct agattttcga
    19081 agaatcgtcc atgaaataga caagcatcca ctttcatttt gatggataag cgtatggaaa
    19141 aataacgttt aatgttcgcc tatatgtagc tataaaagct aaacaaactg ataatatgcg
    19201 atataatacg aacgtattgg ataatataaa caataatatt agtttttcgt atttgcagta
    19261 aatgtgaaaa tatgctatag tttctgtggg aaaagatccc aaaaataata cagagtagaa
    19321 aataaagcgt taagtgctaa gaggatggga tgttgcctct tggacgaagg acgtaatgtt
    19381 cgcggtttta ttttcgcatt cgctgcatga tacgatgtag cagctcttaa aggagatgct
    19441 aaaaatgaag aaacaccggt tagacgcacg tatgattgct attatgggct tattgattgc
    19501 attgatggtc actttgtccc gactggtagc aatcgagacc ccatttatta aaatcagtgt
    19561 cacatttatt ccacaagtga tcatgggcat tctttttggt cctttttggt cagggatagg
    19621 cgcagtttta gctgatttag taggaatggc cctcttctcg aaatctgcat tctttattgg
    19681 atttacattg aatgcattta ttgaaggagc aatctacgga ttctttttct atcgaaaaga
    19741 gatcacttgg aaaaatgcca ttctggctac gcttagtgtc acgctgatca tcaacttatt
    19801 tttgacacca ttatggcttg cgttgatgta ccatgtgcca ttgttcagct gggtcgtttg
    19861 ggcgccccgc ctgttaaaaa cagtaatatg gttaccgatt caatcaattg ccatttatta
    19921 cgtaggacgt agtattcctt acaaaaaaat tttaagaagt ttagcgatcc acgct
//
LOCUS       DAFELK010000055        19304 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFELK010000055
VERSION     DAFELK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.057"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            238..1629
                     /locus_tag="LP433_002228"
     CDS             238..1629
                     /locus_tag="LP433_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL2006363.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAEIDFSQEKIYR"
     gene            1688..2491
                     /locus_tag="LP433_002229"
     CDS             1688..2491
                     /locus_tag="LP433_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2006364.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGKRIVPEYNNAIRVFSKRRNPFNHMTVMFD
                     KKAILEVGNYQPLSGFEDYYLWARLLKAGYKGYNIQETLVYARTGKDMYARRGGMKYL
                     GSGLMGRYRIWKDGLGSVKDFIIVSCGHIFISLLPNQLRGKFYQTQLRK"
     gene            2524..3378
                     /locus_tag="LP433_002230"
     CDS             2524..3378
                     /locus_tag="LP433_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HBL2006365.1"
                     /translation="MKKIQQITLKMSQEIVDFCLKNQLLCYFCGGGAIGTVREQGFIP
                     WDDDLDFFMPREDYEKFYQLWVNSEKSKKYPIQKASKNYNDHNSFTTIRDADTTFIKT
                     YQRDLDIVHGITIDIFPLDVAPVSKFSRKIQKLWALVYALFCSQVVPEKHGGIMATGS
                     KILLSIFRSPRTRYKIWSFAEKQMTKYNNEPTGYVTELCVGPKYMGNVYPAKDFESAV
                     WVPFEDTEMPVPVGYDNYLSQVFGDYMQLPPEKDQVSHHEAVYIDPEHPYTMYKGKYY
                     LTKGAEKK"
     gene            3375..4076
                     /locus_tag="LP433_002231"
     CDS             3375..4076
                     /locus_tag="LP433_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBL2006366.1"
                     /translation="MITAIIIAGGVGKRMGQDIPKQFITIEGKPIIIYTLESFQHHPQ
                     VDRILVVCKSGWEETMWAYIKEFNISKVKWVITGGSKGQESINNGVQFLKDYSEDDDT
                     IIIHDGIRPLVDELVLSDVIVKCKEFGNGVTSLPYNEQIFIKKTEETTEQYVDRNTLR
                     RVSTPQAYQYGKLRAAYDRAVKEDIGMTDSSYTNTMMVDLGETLYFAAGSDKNIKLTT
                     TDDLELFKAYLKMKD"
     gene            4084..5151
                     /locus_tag="LP433_002232"
     CDS             4084..5151
                     /locus_tag="LP433_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL2006367.1"
                     /translation="MMTLIKQPMYQEDLAKVINHTPKIKQLHGKSVLMIGASGMIGSF
                     LIDTLMAANEQLGIKIKVYAMGRNRQKLEKRFASYLELDTFEIVEGDVTEPLPKEIQA
                     DYLIHGASNTHPKAYATDPIGTIMTNLAGTEQVLKHAVATQPVRVLFLSTVEIYGENR
                     GDIEKFTEDYCGYIDCNTLRAGYPEGKRVSESLCQAYIAKHDLDIVIPRLCRTFGPTM
                     LLSDTKASSQFILNAVEQKDIVLKSEGNQYFSYVYVGDAVSAILHLLLEGEKGEAYNV
                     SSENFDLRLKELAQQLADISGKQVIFELPDEIEQKGFSKASTAVLENKKIKETGWKPI
                     FPLNESLVHTVELVKGEKYNV"
     gene            5144..6109
                     /locus_tag="LP433_002233"
     CDS             5144..6109
                     /locus_tag="LP433_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2006368.1"
                     /translation="MCEISIIVPVYKVEKYLRKCVDSILAQTFTDFEVILVDDGSPDN
                     SGKICDEYAEKDNRVRVIHKENGGLSSARNAGIDVARGKYLGFVDSDDYIDEDMYEIL
                     YENLKIHDADISSVELIPFYGDRYKKANKEKKVIILNKKEAIKSVLEGTQFYAYAWNK
                     LYRKELFKDNRYLDGKTFEDAYIIIDLLFQTEKIVVSNEEKYFYLQRNDSIMGKSFSM
                     NNFDVIEAWQYNKEKILDAFPDLHDSYYRRLCWAYFYVLDKMVLSSSYQQIPRKKTVI
                     EFLKKNRNFILTYKGFTKSRKIAIIALSFRVDWYRKLVEQKNKKN"
     gene            6154..7128
                     /locus_tag="LP433_002234"
     CDS             6154..7128
                     /locus_tag="LP433_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2006369.1"
                     /translation="MCRISIIVPVYNVEKYLKKCVDSILGQTFTDFELLLIDDGSTDN
                     SGSICDELAKTDNRIKVIHKENGGLSDARNIGIEVAKGDFIGFIDSDDYIDEDMYAFL
                     YNNILKYDAELSMCGIYDVHKNKEIKKLTPFSQLVTKSEAIELVLDGKLVVANAVSKL
                     YKKELFENVRYPKGKIAEDAAVILKIINQCNKIHVDTSQKYYYYHRGDSITSKKFTKK
                     DFDIIDVWNENEKWIIKNYPQMYDKVHTRVCWAYFVVLDKLVLTEEKGLYQEKKQVRE
                     YLIDNFFFIIKNKRLTFQRKISMLLLTFGIAAYKIPVKYQYKKVKAVN"
     gene            7151..8686
                     /locus_tag="LP433_002235"
     CDS             7151..8686
                     /locus_tag="LP433_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HBL2006370.1"
                     /translation="MKKSRLEYSLINSSISMFIYILRIVIQFVGRSFFIYFLGAKYLG
                     LNGLFTNILSFLSLAELGIGSSIIYSLYKPLAQKDESKVKALMNLYKKTYEFIGIFIG
                     IVGVLIIPLLPLFIKNSTDIPHMYRYYVLFLLNSVLSYFFTYKRSLAIADQKNYLVAI
                     NDFAFLFFMNIVQVIALYFYSNFTLFLIVQILFTLFSNINISRTVDKRYSYLKEKDVV
                     SLDKQTKDEVKKNVIGNMSSKIGGVIVMGTDNILISTFVNLTAVGIYSNYSLIVTSVQ
                     NLCKQITNSITASVGNFAVSNKKKDSFELFKKHFFINHSLIFFSSILLLTLMNPFISL
                     WVGAKYMLPMSTTILIVLNYSVQVYRNTSFVFIESFGLYWSQRKKPIIEAGVNLLLSL
                     LLLIVFDMGINGVLIGTIGSSLGFVIWYEAFIIYKTVFEKRFIHFFLTFWRSFIELII
                     SAIVVFLLNEYLANGGSTFLQFITKTLITIVTTSILYLLLYFRREEFTFIKKILFRYI
                     LKK"
     gene            8743..9858
                     /locus_tag="LP433_002236"
     CDS             8743..9858
                     /locus_tag="LP433_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2006371.1"
                     /translation="MGGASIVASKIAKGLIDSGHEVFFVSYLESEKPQVESKYYDLYE
                     KKIFLFKNFSRFHKILEYRLFGGFVPSRYIKKEKEQLKKVLKKEKPDVIIFNTFIPSV
                     LFSEFLKYEFPTVKLITWMHSDPDYSLNHIAKFYKKEYRKSFERVDSIVCLSQDTKEK
                     LSLYNNHIKVIYNPLTLSGSSLISNLDKKIISFTARYDINIKGFDYLCEVAKNLPVGW
                     AIRIAGDGTEEERKELKRLIEKNGVLDKIICAGALFGDELINHYIESSIFISTSRSEG
                     LPLVLIEAMTYGLPVISFDHGGAKEILQDGNYGILIKNFDVQDMNNEIEKLSNNRLLM
                     EKYQKFSLERAKDFNEKKIIGEWQTLLNELGNEDVRN"
     gene            9855..11270
                     /locus_tag="LP433_002237"
     CDS             9855..11270
                     /locus_tag="LP433_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBL2006372.1"
                     /translation="MRTSIKNFNLWKEWYLYIFFIGMIIRAINFYSLLPSTFDSIFFK
                     LIGISGVLLLGIDFIIKFNKRKVTYNILLIAYMVILVITSFVHKEYGLGENLKTIMWA
                     ILQYFLIYQFAFENSDNKRFFKRISWGFIYSWFVLVSMSMVLFFGKFGYEKYYNARHR
                     IRIGFLESRLFGTFSDINNAAIASLVVIVLILFYLYNKKVTGLNKIIFLINLPLQFIY
                     IVLSGSRSTYVVSIIIVAISSFIVVLKRNGTKKDLKNYILAIVSSIGSVLILFALFNA
                     TKILFQELLPHLKEINFFNFTERHKELMNNSQHINNTQTPDNTLVRKDVAENTDISNA
                     RITIWKSAWEIFKTSWLIGVSPKNVVSYAQSIIPDGYIAKVGIAIHNAYLNVLTSTGI
                     LGIIPFMAFLIKSFVLNVYRIIYNKCIGKDYHFVYCLVILSYALYAALNNELVYENTV
                     GTFVFWLFLGRVNSKNNSSYF"
     gene            11303..12250
                     /locus_tag="LP433_002238"
     CDS             11303..12250
                     /locus_tag="LP433_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL2006373.1"
                     /translation="MLNYLITGGAGFIGSTLANYLGKENNVVVIDDLSMGKKENLDES
                     KHITFIEGDVADKNLMEKVMKEYHFDYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(12290..13450)
                     /locus_tag="LP433_002239"
     CDS             complement(12290..13450)
                     /locus_tag="LP433_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL2006374.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            13615..14790
                     /gene="mltG"
                     /locus_tag="LP433_002240"
     CDS             13615..14790
                     /gene="mltG"
                     /locus_tag="LP433_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBL2006375.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            14926..15405
                     /gene="greA"
                     /locus_tag="LP433_002241"
     CDS             14926..15405
                     /gene="greA"
                     /locus_tag="LP433_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBL2006376.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            15573..16304
                     /locus_tag="LP433_002242"
     CDS             15573..16304
                     /locus_tag="LP433_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBL2006377.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDIEVIRI"
     gene            16301..17368
                     /locus_tag="LP433_002243"
     CDS             16301..17368
                     /locus_tag="LP433_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2006378.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            17375..18007
                     /locus_tag="LP433_002244"
     CDS             17375..18007
                     /locus_tag="LP433_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2006379.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            18147..18812
                     /locus_tag="LP433_002245"
     CDS             18147..18812
                     /locus_tag="LP433_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBL2006380.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            18840..19133
                     /locus_tag="LP433_002246"
     CDS             18840..19133
                     /locus_tag="LP433_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBL2006381.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(19201..>19304)
                     /locus_tag="LP433_002247"
     CDS             complement(19201..>19304)
                     /locus_tag="LP433_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBL2006382.1"
                     /translation="FQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         6740 a         2703 c         3713 g         6148 t
ORIGIN      
        1 tatatgaata ttgtaacttg tgaataagga attagcagga gaatactagt tcagcataaa
       61 ggaagtgatg ggacttctga gacaactttc tgttatgcag aaatacacat ataaacagac
      121 aataaacgct tttccccgtt tcttttaatt tcctttacaa tttggttatt cactaggttt
      181 ttaaactttg ctatggtaag atgatagagg cattatttta tggttaggag tgtatatatg
      241 aataaaaatg gggagtggaa tgcggcacgc agaatattca ttattcttat ggatgtactt
      301 gtattaaatg tatcgatcta tcttagtttt ttgctgaaat tccagggaga agtaccagtg
      361 agaaacttag aaacctttca gcattcagca atttttattt ccatcatctt tattgcgttg
      421 aatattttgt taggagctta tgtattctat aaccgaatga tcagtgatat tgtcttcatt
      481 actgttattg gacaagtact aatagcattg gggatcatgg tagttacttt tgctggccga
      541 tggtttgcat ttccgcgtgg cgtcattttg atctcgttta tcctaggtac gatattactt
      601 agtgtttacc ggatagtcgt ttacaaactg tacttaagag tcagtcgtga taagaaagtc
      661 cttatcgtgg gtttggagaa agatgtcgca ccagctatcc aaaattttca atctaagaaa
      721 aacaataaac ataaggttga agcagtggca atcgataatt attacgaaaa tacaaaaaaa
      781 ttgatcgatg atatggatat cgtctatttg gcttctaaaa tcccagaaga tgaaaaaatc
      841 aacatttatc aattagtgac taaaaaagag aagaaattat ttttaaatac gacttttgag
      901 aatctgacaa tgataaatcc gaatattatg aattttgaag atgaaagcat cattgaagct
      961 tctgggttca gaatccaacc agaatacgaa ctattcaagc gtctctttga tatcatcgtt
     1021 tcgcttattt tactgatcct cgcctcacct tttatgctaa tcacagcgat tttggtaaaa
     1081 acaacttcac ctggaccaat catctataaa caagtacgta ttacgaaaaa tcaaaaggaa
     1141 ttttcaatct ataaattccg ttccatgagt gcgacagctg aagcaaaatc aggaccagtc
     1201 ttggctaaaa gtaacgatgc acgtgtgaca ccagtaggta aatttatccg tgctgtacgt
     1261 tttgacgaat tacctcaaat ctttaatgta ttgaaaggcg atatgtcgat tgtcggtcca
     1321 aggccagaaa gaccattttt cgttgatcag ttcaatgaag aaaatcctta ttattactta
     1381 agacacaatg tacgtgcggg aattaccgga tatgcacaag tatacggaaa atatgtatca
     1441 gattataaca gtaaactacg ttttgatttg ttgtatatca aaaaatattc attactatta
     1501 gatttgaaga ttttacttca aacaatcaaa atcttatttg ataagatgtc atctcaagga
     1561 ctagatgaag atgaaaatat tagttcatta gcagaaatcg acttttcaca agagaaaatt
     1621 tatcgctaga ttggaaaaat tttgagcaaa gaggtaggag agaacattgg aaaataaaaa
     1681 tgtaagtatg ctgctttctt tatatgataa agaaaagcca gagtatttaa aggaagcatt
     1741 aactagtatt tttgagcaaa cagtaatgcc aaaagaaatt gtattagttt atgacggccc
     1801 tataaatgaa aaacttcaag tagttgtcac ttatttccaa caaaaagatc ctcacttgtt
     1861 tacagttgta aaattagaaa aaaatcaagg attggggatt gctttagcaa ttggattaga
     1921 acatacgaaa aatcgcttag tagccagaat ggatacagat gatataatgg aaccccaacg
     1981 attagaaaaa caattagaga tcttccaaaa agatccagaa atagcgattg ttgggagtaa
     2041 tattgaggaa tttactggca cgcttagcaa tgttatcgga aaaagaattg tacctgaata
     2101 taacaatgca attcgtgtat tttctaaaag aagaaatccc tttaatcata tgaccgttat
     2161 gtttgataaa aaagctattt tggaagtggg aaattaccaa ccattaagtg ggtttgaaga
     2221 ttattatctt tgggcaagat tattaaaggc aggttataaa ggatataata ttcaagaaac
     2281 attagtctat gcgcgaactg gcaaagatat gtatgcaaga agaggcggaa tgaaatatct
     2341 tggttctggt cttatgggtc gttatcgtat ctggaaagac ggtttagggt cagtaaaaga
     2401 ttttataatt gtttcttgcg gacatatttt tattagctta ctaccaaatc aattaagagg
     2461 aaaattttat caaacgcaat taagaaaata ggaggttttt ctttgtatag cactgatcca
     2521 aaaatgaaaa aaatacaaca gattacgttg aaaatgtctc aagagattgt tgatttttgt
     2581 ctaaaaaatc aacttctttg ttatttctgc ggtggtggtg ccatcggtac tgtgagagaa
     2641 caagggttta ttccatggga tgatgattta gatttcttta tgcctagaga ggattatgaa
     2701 aaattttatc aactatgggt taattcagaa aaaagtaaaa aatatcccat acagaaggct
     2761 tctaaaaatt ataatgatca taattctttt acaactatcc gcgatgcaga tactacattt
     2821 attaaaactt atcaaagaga tttagatata gtccatggaa ttactattga tattttcccg
     2881 ttagatgttg cccctgtttc gaaatttagc cgtaaaattc aaaaactatg ggctttagta
     2941 tatgctttat tttgttctca agtcgtccct gaaaaacatg gtggaataat ggctacaggt
     3001 agtaagatac tcttatctat tttccgctca cctcgtacga gatataagat atggtctttt
     3061 gctgaaaaac aaatgacaaa atataataat gaaccaacgg gctatgtgac tgaactttgt
     3121 gtcggaccta aatacatggg aaatgtttat cctgcaaaag actttgaatc tgctgtgtgg
     3181 gtgccattcg aagatacaga gatgccagta ccagttggtt atgataatta tttaagtcaa
     3241 gtttttggtg actatatgca gcttccgcct gaaaaagatc aggtttctca tcatgaagca
     3301 gtttatattg atccagaaca tccatacaca atgtacaaag gaaaatatta tttaactaaa
     3361 ggagcagaaa aaaaatgatt acagctatta ttattgctgg tggtgtgggt aaacgaatgg
     3421 gacaagatat cccaaaacag ttcattacaa ttgaaggaaa acctattatt atctatactt
     3481 tagaatcatt tcaacaccat cctcaagttg accggatttt agtcgtttgc aaatctggtt
     3541 gggaagaaac gatgtgggcg tatatcaaag aattcaatat tagcaaagtc aaatgggtca
     3601 ttacaggtgg atcaaaggga caagagtcga tcaataatgg tgttcagttt ttgaaagact
     3661 attctgaaga tgatgatacg atcatcatcc atgatggaat ccgtccacta gtagacgaac
     3721 tggtattgtc agatgtaatc gttaaatgta aagaatttgg taacggtgta acctctctac
     3781 cttacaacga acaaattttt atcaagaaaa cagaagaaac gacggaacag tatgtcgatc
     3841 gtaacacatt gaggcgtgtc tcaactccac aagcttatca atacggaaaa ctacgggcag
     3901 catatgaccg ggcagtgaaa gaagacatcg gtatgactga ttcttcttat acgaatacca
     3961 tgatggtaga tttgggagaa actttatatt ttgctgctgg ttctgataaa aatatcaaat
     4021 tgacaacaac agatgatcta gaattgttca aagcatattt aaaaatgaaa gactaggtga
     4081 aagatgatga cgttgattaa acaaccaatg taccaagaag atttggcaaa agtaatcaat
     4141 catacaccaa aaataaaaca gctacatgga aaatccgttc tgatgattgg tgcttctgga
     4201 atgatcggct cttttttgat tgatacgttg atggctgcta atgaacaact aggcatcaaa
     4261 atcaaagttt atgcaatggg cagaaaccgt cagaagcttg aaaaaaggtt tgccagttat
     4321 cttgaattag atactttcga aattgttgaa ggtgacgtca cagaaccctt accaaaagaa
     4381 attcaagctg actatttgat acacggtgca agtaacacac atcctaaggc ttacgcaact
     4441 gatccaatcg gtacgatcat gactaatctt gcaggtacag agcaagtatt gaaacatgca
     4501 gtagcaaccc aaccggttag agtattattt ttatcaacag tagaaatcta tggcgaaaat
     4561 cgaggcgata tagaaaaatt cacagaagat tactgtggat acatcgattg taatacactg
     4621 agagcaggct accctgaagg aaaaagagtc agtgaatcat tatgccaagc ctacatcgca
     4681 aaacacgacc tcgacatcgt gattccaagg ctttgccgta cgtttggtcc gacgatgctt
     4741 ttatctgata cgaaagcatc ctcacaattt attttaaatg cagtcgaaca aaaagatatt
     4801 gttttaaaaa gtgaaggaaa ccaatatttt tcgtatgtat atgttggaga tgctgtttct
     4861 gctattcttc atttactgct tgaaggagaa aaaggagagg cgtacaacgt ttcttcagaa
     4921 aactttgatt tacgactaaa agaattagcc caacagctag ctgatatcag cggcaaacaa
     4981 gtaatttttg aattgccgga tgagattgaa caaaaaggtt tctcaaaagc tagcacagca
     5041 gtacttgaaa ataaaaaaat taaagagaca ggttggaaac caatttttcc tttgaacgaa
     5101 tcattggttc atacagtaga attagttaaa ggtgagaaat ataatgtgtg agattagtat
     5161 tattgttcct gtgtataaag ttgaaaaata tttaagaaaa tgtgtagatt cgattttagc
     5221 ccaaacattt actgattttg aagttatatt agtagatgat ggatctcctg acaatagcgg
     5281 gaaaatctgt gatgagtatg ctgaaaaaga taatcgagta cgtgtgatcc ataaagaaaa
     5341 cggcggatta agcagtgcta gaaatgcggg gattgatgtt gcgagaggca aatacttagg
     5401 ctttgttgac agtgatgatt atattgatga agatatgtat gaaattttgt atgagaattt
     5461 gaaaattcat gatgccgaca ttagctctgt tgaattgatt cctttttatg gtgatagata
     5521 taagaaagct aataaagaaa agaaagtaat tatattaaat aaaaaggaag caataaaatc
     5581 tgttttagaa ggaacgcaat tttatgcata cgcatggaat aaactttatc gtaaggaact
     5641 ttttaaagat aatcgttact tggatggaaa aacatttgag gatgcatata taataataga
     5701 tctattattt caaacagaaa aaattgttgt ttccaatgaa gagaaatatt tctatcttca
     5761 aagaaatgat agtattatgg gaaaaagttt ttctatgaat aatttcgatg ttatagaagc
     5821 atggcaatat aacaaagaga agattttaga tgcttttcca gatttgcatg attcctatta
     5881 tcgccgacta tgttgggcat atttttacgt gttggataaa atggttttat caagtagtta
     5941 tcaacaaatt ccacgtaaaa aaacagtaat tgaattttta aagaagaaca gaaattttat
     6001 attaacttat aagggattca ctaaatcgcg caaaatagct attattgctc tgagctttag
     6061 agtagattgg tataggaaat tggttgaaca aaaaaataaa aaaaattaga atgtttaaat
     6121 tagtaaataa aagaaaagga attgaaaact aaaatgtgca gaataagtat aatagttcca
     6181 gtttataatg ttgaaaaata tttaaaaaag tgtgtcgatt caattctagg ccaaacattt
     6241 accgattttg aattattatt aattgatgat ggttctacag ataattcagg aagtatatgc
     6301 gatgaacttg cgaaaacaga caaccgaata aaagtgatac ataaggaaaa tgggggtcta
     6361 agtgatgcca gaaatattgg tattgaggta gcaaagggag attttattgg gtttatagat
     6421 agtgatgatt acattgatga agatatgtat gcatttttat ataacaatat attgaaatat
     6481 gatgcagagt tatcaatgtg tggtatttat gacgtccata agaataaaga aattaaaaag
     6541 ttaactcctt tttctcaatt ggttactaaa tctgaagcaa ttgaattagt attagatggt
     6601 aagctagttg ttgctaatgc agtaagcaag ctatataaaa aagaattatt tgagaatgtg
     6661 agatatccaa aaggaaaaat tgctgaagac gcagcagtaa tactgaaaat tatcaatcag
     6721 tgtaataaaa tccatgttga tacttctcaa aaatattatt attatcatcg tggagatagt
     6781 attactagta aaaaatttac aaaaaaagat tttgatataa ttgatgtatg gaatgagaat
     6841 gaaaaatgga ttattaaaaa ttatcctcaa atgtacgata aagtacatac tagagtttgt
     6901 tgggcttact ttgttgtgtt agataaatta gttttaactg aagaaaaagg actgtatcaa
     6961 gaaaaaaaac aagtaagaga gtatttaatt gataatttct tttttattat aaaaaataaa
     7021 cgattaactt ttcaaagaaa aatatctatg ttattgctta cttttggaat tgctgcgtat
     7081 aaaataccgg ttaaatatca gtataagaaa gtaaaggctg ttaattaatg ctttagttag
     7141 gatgaattag atgaaaaaaa gcaggttaga gtattcttta ataaattctt ctatatcaat
     7201 gtttatatat attttaagga tagtaataca atttgtaggt agaagttttt ttatttattt
     7261 cttaggagcg aaatatttag gattaaatgg tttatttaca aatatactta gtttcttgtc
     7321 gttggctgaa ctaggcatag gctcttctat tatttattcc ctatacaaac cattagccca
     7381 aaaggatgaa agtaaagtaa aggctttaat gaatttgtat aagaagacat atgaatttat
     7441 tggtattttt atcggcatag taggagtatt gattattccg ctgttacctc tatttattaa
     7501 aaatagcaca gacataccac atatgtatcg atattatgta ttatttttat taaattcagt
     7561 tcttagttat tttttcacgt ataaaagatc acttgcaata gcagatcaaa aaaattatct
     7621 ggttgcgatt aatgattttg cctttttatt ctttatgaac attgtacaag taattgcttt
     7681 gtacttttat tctaatttta ctctatttct aatagtgcag attttgttta ctctattttc
     7741 taatataaat atttccagaa cagttgacaa gagatattca tatttaaaag agaaagatgt
     7801 agtttctcta gataagcaaa caaaagatga agtaaagaaa aatgtcatag gtaatatgtc
     7861 ctcaaaaata ggcggggtta ttgtaatggg gacagataat atattaattt ctacatttgt
     7921 taatttaaca gctgtaggaa tttattctaa ctattcattg attgtcacaa gtgtgcaaaa
     7981 tttatgtaag caaattacta attctatcac ggcaagtgta ggaaattttg ctgtatcaaa
     8041 taaaaaaaag gattcatttg agctatttaa aaaacatttt tttatcaacc actcactaat
     8101 ctttttttct tctatattgt tattgacttt aatgaatccc ttcattagct tgtgggtagg
     8161 agccaaatac atgctaccta tgtcaacgac tattttaatt gttttaaatt atagtgtaca
     8221 ggtttataga aatacatcct tcgtttttat agagtcattt ggtttatatt ggtctcaacg
     8281 gaaaaagcct ataattgaag caggtgtaaa cttgttatta tctttgcttt tgttaatagt
     8341 ttttgatatg ggaatcaatg gagtacttat agggactatc ggatcgtctc taggatttgt
     8401 gatttggtat gaagcattta tcatatataa aacggtattt gagaaacgtt ttattcattt
     8461 ctttttaact ttctggcgaa gttttataga attaataatt tcggcaatag tcgtttttct
     8521 attaaatgaa tatttagcaa atggaggcag tacgttcctt caatttataa ctaaaacctt
     8581 aataactata gtaacaacat cgatattata tttgttatta tattttagaa gagaagaatt
     8641 tacatttatc aaaaaaattc tttttaggta tattttaaaa aaatagcttt ctataaagga
     8701 gtgttttatt tgaaaatagc tatactatct ccagctttct caatgggagg agctagtatc
     8761 gtggcctcaa aaattgcaaa aggattaata gatagtggcc atgaagtttt ttttgtttct
     8821 tacttagaaa gtgaaaaacc acaagtagaa tctaagtatt atgatttata cgaaaaaaaa
     8881 atttttttat ttaaaaattt ttctcgattt cataagatat tagagtatag attgtttgga
     8941 ggctttgttc ctagtagata tataaaaaaa gaaaaagaac aactaaaaaa agttctaaag
     9001 aaagaaaaac ctgatgtcat catattcaat acttttatac ctagtgtact attctccgaa
     9061 ttcctaaagt atgaatttcc aacagtgaaa ttaattactt ggatgcactc tgatcctgat
     9121 tacagcttaa atcatattgc taaattttat aaaaaagaat atagaaaaag ttttgaacgc
     9181 gtggattcca ttgtttgtct ttcgcaagat acaaaagaaa aactttcatt atacaataac
     9241 catattaaag ttatttataa cccattgaca ttaagcggct ctagtttaat aagtaacctt
     9301 gataaaaaaa ttatttcatt tactgccaga tacgatataa atattaaagg gtttgattat
     9361 ttatgtgaag tagctaaaaa cttacctgtt ggatgggcta taaggattgc tggagatggt
     9421 acagaagaag aacgtaaaga gctgaaaaga ttaattgaga aaaatggtgt gttagataaa
     9481 attatttgcg caggtgcatt atttggagat gaattaatca atcattatat agaaagttct
     9541 attttcatat ctacttctag aagtgaggga ctaccattag tgttgataga agcaatgact
     9601 tatggattac ctgtaataag ttttgatcat ggtggtgcta aggaaatatt acaagatgga
     9661 aattatggaa ttttaattaa gaattttgac gtacaagata tgaataatga gatagaaaaa
     9721 ttgtctaata atcgtttact tatggaaaaa tatcaaaaat tctctttaga aagagctaag
     9781 gattttaatg aaaaaaaaat aattggtgaa tggcaaacat tgttaaatga attaggaaat
     9841 gaggatgtta gaaattgagg acttcgatta aaaattttaa tttatggaaa gaatggtatc
     9901 tatatatatt ttttataggg atgattattc gtgcaataaa tttttatagt ttattaccgt
     9961 ccacttttga tagtattttt tttaaactta taggaatttc aggagttttg ctattaggga
    10021 tagatttcat aattaaattt aataaaagaa aagtaactta taacatttta ttgatagcat
    10081 atatggtgat tttagtaata acgagttttg ttcataaaga atatggtcta ggagaaaact
    10141 taaagactat aatgtgggca atcttacagt attttttgat ttatcagttt gcttttgaga
    10201 atagcgataa taaacgattt tttaaaagga taagttgggg atttatttat agttggtttg
    10261 ttttagtatc aatgtcaatg gttcttttct ttggtaaatt cggctatgag aaatattata
    10321 atgctagaca taggatcaga attggttttt tagaatcaag actgtttggg acgttttctg
    10381 atattaacaa tgctgctata gcatctttag ttgttattgt cctaatctta ttttatcttt
    10441 ataataaaaa agtgacagga ttaaataaaa tcattttttt aattaatctt ccattacaat
    10501 ttatttatat agtattaagt gggtcacgat ctacctatgt ggtaagtata ataatagttg
    10561 ccatatcatc ttttattgtt gtgttaaaac gaaatggaac aaaaaaagat ttaaaaaact
    10621 atatccttgc tatagtatct tctattggtt ctgttctgat tttattcgct ttgtttaatg
    10681 caactaagat actttttcaa gaattattac ctcatttaaa agaaataaat ttttttaatt
    10741 ttacagagcg tcataaagaa ttaatgaata atagtcaaca tattaataat actcaaacac
    10801 ctgataatac tcttgttagg aaagacgtag ctgaaaatac agatatttct aatgctagaa
    10861 ttactatatg gaaaagtgca tgggaaatat ttaaaacaag ttggcttatc ggagtctctc
    10921 cgaaaaatgt agtatcttat gcacagtcaa ttattccaga tggatatatt gcgaaagtag
    10981 gaattgccat tcataatgca tacttgaatg tattaacatc gacaggtatt ctaggaataa
    11041 ttcctttcat ggctttttta ataaagagtt ttgtgctgaa tgtttatcga atcatctata
    11101 ataaatgcat tggtaaagat tatcattttg tttactgttt agttatttta tcttatgcac
    11161 tatacgcagc tcttaacaat gaattagtct atgaaaacac tgtaggaacg tttgtttttt
    11221 ggctattttt aggaagagtt aatagcaaaa ataattctag ctatttttag taataaattt
    11281 tatcttgaaa agaggagaaa aaatgttgaa ttacttgatt accggtggcg ccggcttcat
    11341 tggctcgacg ctcgcgaatt atctaggaaa agaaaacaat gtagttgtga tcgatgattt
    11401 atcgatgggg aaaaaagaga atctggatga atcgaagcac atcacgttta ttgaagggga
    11461 tgtcgctgac aaaaatttga tggaaaaggt catgaaagaa taccatttcg attatatttt
    11521 ccatctagct gctgtagcta gtgtggcaga ttctgtagaa cgtcctctag aaactcatcg
    11581 tgtaaatttt gacagtgcgc ttttattgct tgaattggta cgaaaatatc aatctggttt
    11641 aaaacgattg gtatttagtt catcagctgc agtttatggc gatgaaccaa cgttgccaaa
    11701 aaaagaagaa tcggtcatcc gtcctttaac accatatgcc atcgataagt ttgcagcaga
    11761 acaatatgtt ttggattact gtcatttata tgatgttccg actagtgctg tccgattttt
    11821 taacgtttat ggtccaaatc aaaatcctaa ctctccatat agcggagtta tttcgattct
    11881 agtggaccga tacaaaaaac aattggcagg agaaaaaaca gaatttactt tatttggtga
    11941 tggtagccaa tctagagact tcgtttatat agaagatgtt atacaagcac ttttacttgt
    12001 tgctaaggaa gaaaaagctt taggacagca attcaatgtc ggtacaggaa aaagcactac
    12061 gctacttgaa ttgattcatt caattgatca aatcttagga acagagctag cgcttaaata
    12121 tgaagcggag cgttcagggg atattcgtga ttctttagcg gatatttcaa agatccgttc
    12181 tttaggttat caacccaaat ttgatatatt gaacggaatg gaacgttatt taaagacaga
    12241 aatcgattga aacaaaaaac cagcatcctg ctggtttttt tgtctcgact tagcttttta
    12301 aattaacacc ttccatcagt tcgtaaatct gatttcttaa atcagtggcc ggcaatttga
    12361 tgtttttatc agattggata ttactttcca tgacgattgc atcttttgtg tcttttttca
    12421 tcgccgctac tgcatggaat cgattgatat ttccctgagc aaggatataa tcatttccac
    12481 tgtaaacacc gccgctgtaa ggatgtttat caccattatt ttgccacaat gagaaaagta
    12541 gttcttttgg tataatatcg ccagacagaa cactggtaaa gaatttgttc aagtcataaa
    12601 cagacatact tatatttcct gtgcctaatt catttcggat gtctgtttca ggctcgacca
    12661 atgcttttga ataatcgtca gttgcagaca tttggtaaga tacagcatgc tgaggggaat
    12721 tttttacatt ttcataaaaa tctgtatgtt ctagatggag tggccgaatg atttcttttt
    12781 ttaaaagagt ttcataaggc tgattcatta gtttgatcaa tacccctgta agcaatgtat
    12841 aatttaatgg ttcataatga tacgtatcat aaccagtaaa tttcaaatga tgaagggcaa
    12901 actgaatgat ctcactatct gacataggtt tttttggaga cgcggttcga tgaagaccag
    12961 agcgcatgta aagcatattt ttgattgaga tttgctgact tccaggaatc tgaggataaa
    13021 attcagatag ctttgtgtca aaagttatct tgccagattg aatttgtttt aggataagta
    13081 aagcagtcat cgctttttgg atcgaaccga tttgatagta aagagaagga gaattcgatt
    13141 cttttatgcg tagatttgcg tacccatatc ctttttctaa tatcactcga ttatttttgc
    13201 gtacataaat cgaaccgata taatctgatt tttgcagtaa ttgatcaatt ttgctggcaa
    13261 gcatctgctc attagatgtt aaattggaag caagttgtgc gggttccgtt ttataaattt
    13321 gtggttgagg ttgttttgtt aattgccatc ctgtaatgat gcctgttgaa aagaagctga
    13381 cagccagcaa caaaactgcg agaaaagaaa gagagatctg ctgttttttt tgatgttttc
    13441 cttttgccat attaaatcct tcctatccat ttttaactat ttttcattgt aatcctcaaa
    13501 aagagcattt gccacttaca attttgacat aatatttggt aaaataattc acggcagtag
    13561 aaatttcatg tataataaac agagttacga agatgatagt aaggaggagt tgttttgtca
    13621 ggaaacaaac aacacccaag caaagacaaa aaagaagcca gtaaggcagc tacagcagat
    13681 ataatcgaca agcggagaaa tctgcgtaaa aaagaagata agatcgtgag gaagatcatt
    13741 ttagtgatcg ctcttacatt attgattatt ggcggatttc tcgggtttac cgtatatcgt
    13801 tatgtagata gcgggttgaa gcctttagat aaatcggacg accaattagt ccaagtggaa
    13861 atcccaagcg gctcttctaa taagcagatt ggcgaaattt tggagaaaga caatattatt
    13921 aaaagtggga ttgttttcaa ttattataca aaatttaaaa acttaactgg ctttcaagct
    13981 ggttattatc agttagcgcc taatatgact cttgatgaga ttggcaagca gttgcaagaa
    14041 ggcggcacat ctgagccaac aaaagttgca gatgggaaaa ttgccattcc agaaggctac
    14101 gacatcgatc agattgctga gcgggtagcg aaggtaactg gtaaagacaa gaaagaattt
    14161 ttagatttag taaatgatga gactttcttt aacgagttgt atcaaaaatt cccagaattg
    14221 ttggaaagtg cctctaaagc tgagaacaca aaataccgtt tggaaggcta cttattccca
    14281 gctacttatg attactacac gagtacttcg cttaaggatc ttgtgattga gatggtgaac
    14341 aaaacaaata cggtcatgca aaactattat tcagctatca aacagaaaaa tttgactgta
    14401 caagaagttt taactttggc ttctctagtt gaaaaagaag gcgtaaaaga aaatgatcgt
    14461 aaaaatattg cacaagtctt ctttaaccga atcaaggcaa atatgccact tcagtcagat
    14521 atctctgttt tatatgcatt aggagaacat aaagaattgg tgacgtatga agatacagct
    14581 gtagattcac catacaattt gtataccaat accggctatg ggcctggtcc ttttgacaat
    14641 ccaagcgaag aggcaatcaa ggcagtatta gaaccagcag aaaatgacta ttattatttc
    14701 gtagcagata cgagcactgg aaatgtttat ttcgctaaaa cgtatgaaga acatatggaa
    14761 ctagtgcaaa aatatgtaaa taattcttag aaaaacaggg gctagtcatt gatcattttt
    14821 agaaaaacat ttacatttta agaaaagcgt ggtaatcttt tttggactat attcctcaaa
    14881 agattacctt ttgcggtatt ttatcgaaaa aaggagacgt tacacatggt agagaaagtt
    14941 tatccaatga ctctagaagg taaagaaaaa ttagaaaaag aattagaaga actaaaaaca
    15001 gttaaacgcg gagaaatcat tgaacgaatc aaaatcgctc gcggtttcgg agatctttcc
    15061 gaaaactccg aatacgaatc agctaaagat gaacaagcat ttgttgaagg aagaatcaca
    15121 acaattgaaa atatgatccg ttttgcacaa atcatcgata atgacggcgt agatgcagat
    15181 gaggtatcga tcggtaaaac agttacgttc atcgagttgc ctgatggaga tgaagaagag
    15241 tacacgattg tcggaagtgc tgaagcagac ccgttttctg gaaagatttc caatgattct
    15301 cctatcgcgc aagcattgat tggcaaacgt aaaaatgatg aagtaaccat tgctacacca
    15361 ggtggcgata tgttagttaa aatcgtcaaa gtagaacaag cgtagtctga ctgaaagatc
    15421 tagagagttc atcttactga tgacgcactc tagatctttt ctctttgagt attgcaggtt
    15481 tcactgaacg atcttacatc taaagtccta tagccaacag tcaaaaaaat aggtatgatg
    15541 aaatgagaat gtgtcaggag ggagaaaaag cgatgaatag ttcttggcgt ttttttgtgg
    15601 tagtcgaagc actgctgctg ttatttgctg tttggcaaat cgtaaacaat actggacttt
    15661 tgcttttagt aatattcggt attttcaata tatatctagc tatgcgcaaa tatcctcgta
    15721 ctaaatttca aaattttcaa ttgatcttag ggagcttggt catttttttt agcttagtca
    15781 acagtcctgc tttatggatg atggttgtat tggccgtttt atttatcggg ctgaaaggtg
    15841 tagagatttc aggaatagat ttgacaaaaa atgctttttg gcgaaaaaaa cagatcatga
    15901 tggtccaaac agagcaatta aaaacacata ataatgagcg taaaagacag caattatttg
    15961 gtaaccaacg tattggaaac gacgtctatg aatgggatga tatcaacatt gccatcattt
    16021 ctggtgatac tatcatcgat ttgggcaata cacttttgcc aaaagatgat aatattgtga
    16081 ttgtaagaaa agggataggc agaacacgga tcttagtacc cctgggagtg gctattcgtt
    16141 tagagcatgc gacattagta ggaaatgtct tgtttgaaga agagcagttt tccttaaaaa
    16201 acgaacagat caaaatctgc agcagtgatt atgatgaaaa tcctcgcaga ttgaagatca
    16261 ttaccaatac tttggttgga gatatcgagg tgatacgaat atgatgggaa gaatatccaa
    16321 agcaatgcta gctgtttatt cggggattgc ggctttcctt attattctat tttcactttt
    16381 cacttatttt tatgccagta accaaagtca ttggtgggga gaattgctgc gtgcgcgttt
    16441 attatacgtt ccgcttatct tccatttgat ggcaatttca ttaggtgtag gattgatcgt
    16501 atttctattg ttatcactta ttcaaaaggc aaaatacggg aaaatcgaag aaaagcttcg
    16561 tgcactttct tctggcaatt atgaatccaa acttttgcat cagccgatcc caagcgcgtc
    16621 ggatgatctg tacatcaaag atattgatat ggaaattact aaaataaaag aaaaaatgat
    16681 cgaagtatcc agtgaattac agattatgac tagccgtcct caatatgtag atggacaaac
    16741 caaagaagag attttaaaat tagaaaggca tcgattagct cgtgagcttc atgattcagt
    16801 ttcacagcaa ttatttgcag cgatgatgat gatgtcggca ttgacggagc aagcagaaaa
    16861 aagtgagaca ccagaaatgt tccgtaagca gttgaaaatg gtggcagaga tcatcaacgc
    16921 ttcccagtct gagatgcgtg cgctgcttct tcatctgcgt ccagtcaatt tagaagaaaa
    16981 aagtttaaaa caaggcattg agcagttatt gaaggaattg cagaataaaa tccagatttc
    17041 gctaaaatgg gaggtagaag atgtaaaatt aactagttcc attgaggatc acttgttccg
    17101 aatcgttcaa gaattgttat caaacacatt aagacatgct aaggctaatg aattagaagt
    17161 ctatttgcat aaaatagata acaatctttt attacgtatc attgacgacg ggacaggatt
    17221 taatatgaat gaaaccaaaa cgggaagtta tggattgaac aatatcaaag aacgagtagc
    17281 tggtattggt ggaacagtaa aaatcattag ttttaaaggg caaggtacga gcgtggagac
    17341 caaggtccct ttgatgaagg aggcatagat aaagatgata aaagttttat tagtagatga
    17401 ccatgaaatg gtacgcttag gcgtctcttc ttatttatct atccaagaag acattgaagt
    17461 gattggagaa gctgaaaatg gacgtcaagg ctatgaaaag gcgatggcac ttcgaccgga
    17521 tgtcatttta atggatctag tcatggaaga aatggatggc atcgaatcaa caaaagcaat
    17581 cttaaaagat tggccaaaag ccaaaatcat tatcgtcaca agttttattg atgatgaaaa
    17641 agtttatcct gcaattgaag caggagcagc aggatatttg ttgaagacgt ctacagcaca
    17701 tgaaatagct gatgctataa gggctacgca acgcggcgag cgagtactag aacctgaagt
    17761 gacaacaaaa atgatggaaa aaatgagtcg gcgaaatgat ccagtattgc atgaagaatt
    17821 aacgaatcga gaaaatgaaa ttttgatgct gatttctgaa gggaaaagta atcaggaaat
    17881 cgcggatgaa ttgtttatca cactgaaaac agtcaaaacg catgtgtcga atatattagc
    17941 taagttagag gtagaagacc gaactcaagc agctatctat gcgtttaaac atggtttggt
    18001 gaaataaaaa cgatgataaa gaggataatc aaaagctgag aaaataacta ttatttttct
    18061 tggctttttt acaataatga tgcttgcttt tgtttttgga aaggctttgt tatactgaga
    18121 aaagaagata ctaaaggagg aaaatggtga aacaaaattt tgcaattgta ggccttggac
    18181 gatttggcgg aagcatctgc cgtacactga tcgaagctgg acaagaagta ctggctattg
    18241 acagtaatga agatcgagtc aatgaatata tgaatatagc cacccatgct gttgtggcaa
    18301 atgcacagga tgagatgaca cttcgttcat taggtataag aaatttcgat catgtaattg
    18361 tcgctattgg agaagatatc caagccagca tcttagttac tctgatggta aaggaaatgg
    18421 gcgtaccgaa tattttagca aaagcccaaa atgagtacca tgcccgtgta ctagagaaga
    18481 tcggagcaga tcgtgtcgta caccctgagc gagacatggg gatacggatt gcacataact
    18541 tagtatcaaa gaatattcta gactacttag agctgtcaga taaatattct ttagcagaaa
    18601 tccgagtctc caatcctaaa tttttcaaca aaacattagc tgaattaaat ttcaggcaac
    18661 gttttgactt aacagtagtc gccatacgaa gagtagatca aacggttatc gcttctcctg
    18721 cagcagatga atatgttcgt gaaaatgata atctactggt tattggagag acaggcgatg
    18781 tggatattct agacgataag atgaatcaat agaaagaaaa gagaaagtag gttgttggga
    18841 tgaaattaac ggtaacgcca aaagcacaaa agtggtttga ctcagaaatt gatctgccag
    18901 aaacttacgg aatacgtttt tttggaaaag tctacggcaa aacagaggtt catgatggtt
    18961 tttcgattgg aatgtcagtt gaacagccag aacatcctgt aaagaaagtg gaaatggatg
    19021 ggacactttt ttttatcgag gaagcagatg aatggttctt taaaggatat gatttacttg
    19081 ttgattatga tcccaacctg gaggagccaa cctatcactt taaaaaacaa taaaaaaaga
    19141 gagggtgaca caatttttgt caccttctct tttttctttt gaaaatattg ttttcagcta
    19201 ttaatatcct gcagacaatt ttacttgatt ggtttgaagc tcatgggtgg caaagtagct
    19261 tttcagattg gttaaaaaaa tagccattaa tttcttttga aaat
//
LOCUS       DAFELK010000056        17819 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFELK010000056
VERSION     DAFELK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.058"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            7..1755
                     /locus_tag="LP433_002248"
     CDS             7..1755
                     /locus_tag="LP433_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2006383.1"
                     /translation="MSAVVLAACGGGGTDTSGNNSGGNGNNKEELTFPIATKNNDDAI
                     EDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDFRITDDGAATLD
                     LDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYDDTFRNIVGMEE
                     YHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHTLEGVAIKDMES
                     SDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKSVPMASATEALN
                     SKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNADTKSVEYNPDSK
                     MADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEMKGFTQDLDKAK
                     KLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQQWKEIGLDVQY
                     TTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAFNYTRYESEENT
                     KLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVNDRVKDWDWSYD
                     VPNPWANVSVTADSRS"
     gene            2103..2789
                     /locus_tag="LP433_002249"
     CDS             2103..2789
                     /locus_tag="LP433_002249"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBL2006384.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            2809..6390
                     /gene="smc"
                     /locus_tag="LP433_002250"
     CDS             2809..6390
                     /gene="smc"
                     /locus_tag="LP433_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBL2006385.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            6399..7208
                     /locus_tag="LP433_002251"
     CDS             6399..7208
                     /locus_tag="LP433_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2006386.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            7219..8217
                     /gene="ftsY"
                     /locus_tag="LP433_002252"
     CDS             7219..8217
                     /gene="ftsY"
                     /locus_tag="LP433_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBL2006387.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            8404..10671
                     /gene="gshAB"
                     /locus_tag="LP433_002253"
     CDS             8404..10671
                     /gene="gshAB"
                     /locus_tag="LP433_002253"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBL2006388.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(10760..11212)
                     /locus_tag="LP433_002254"
     CDS             complement(10760..11212)
                     /locus_tag="LP433_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBL2006389.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            11362..12312
                     /locus_tag="LP433_002255"
     CDS             11362..12312
                     /locus_tag="LP433_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL2006390.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            12305..13264
                     /locus_tag="LP433_002256"
     CDS             12305..13264
                     /locus_tag="LP433_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL2006391.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            13261..14016
                     /locus_tag="LP433_002257"
     CDS             13261..14016
                     /locus_tag="LP433_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2006392.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            14039..14992
                     /locus_tag="LP433_002258"
     CDS             14039..14992
                     /locus_tag="LP433_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2006393.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(15636..15932)
                     /locus_tag="LP433_002259"
     CDS             complement(15636..15932)
                     /locus_tag="LP433_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBL2006394.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            16287..16643
                     /locus_tag="LP433_002260"
     CDS             16287..16643
                     /locus_tag="LP433_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL2006395.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            16653..17552
                     /locus_tag="LP433_002261"
     CDS             16653..17552
                     /locus_tag="LP433_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBL2006396.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT         5972 a         3100 c         3774 g         4973 t
ORIGIN      
        1 gcgctgatgt ctgctgtcgt tcttgcagca tgcgggggcg gaggtacaga tacctctgga
       61 aacaactctg gaggcaacgg caataacaaa gaggaattaa cttttccaat tgcaacaaaa
      121 aataatgatg atgcaatcga agacggcgaa ttagaagctg cggtcgcaac ggacagtcag
      181 tttaaaggat tgttccagtg ggagttttac caagattcat atgatgcagc ttttatggct
      241 ccttctcatg aaccgctatt tgcaaacgat gacgatttca gaatcacaga cgacggagct
      301 gcaacgcttg atctagatga agatacgaaa aaagcgacaa tcaaagtaaa agacaacgtc
      361 aaatggtcag atggtgaaga tgtaacggcg gacgatgtga ttttccctta cgaaatcatt
      421 gggaataaag attacactgg tatccgttat gacgacactt tccgtaacat cgtaggtatg
      481 gaagaatatc atgatggaag tgccgacaca atctccggaa tcaaaaaaat agacgacaaa
      541 acagttgaaa tcgaatataa agaagtaaac ccaagcatgc ttcaatcggg tggtggtatc
      601 tggtcatatg cagcaccaaa acatacgtta gaaggtgtag caatcaaaga tatggaatca
      661 agcgatcaag tacgtaaaaa tccagtgact tttggccctt attacatgag taatatcgtt
      721 gcaggagaat cagtagaata cttgccaaac gagcactact ggaatggtac gcctaaattg
      781 aaaaagatca cgatgaaatc tgtaccgatg gcaagtgcaa ctgaagcatt gaactctaaa
      841 ttatatgata tgattttcca aatgccaaca gatacttacg atacctataa agaaattgct
      901 ggctatacaa acttaggccg tgaacaaact tcttatactt atctaggatt caagttaggt
      961 aaatggaatg cagatacaaa gagtgtggaa tacaatccag attcaaaaat ggctgataaa
     1021 tcattacgtc aagcaatggg ctatgcatta gataataatg cagtaggtga acgtttctat
     1081 gcaggtttga gaagcaatgc gacttcattg attcctccag tattccagtc ataccatgat
     1141 gatgagatga aaggattcac acaagatcta gacaaagcga aaaaactatt agatgatgct
     1201 ggctacaaag atgtggatga cgatggttta agagaagaca aagatggaaa taaactaaca
     1261 atcaactttg cttcgatgtc cggtggggaa acagcgcaac cattggcaga ttactatatc
     1321 caacaatgga aagaaattgg tttggatgtc caatacacaa caggtcgtct gatcgaattc
     1381 aattctttct atgataaatt agaaaacgat gatcctgaaa ttgatgttta ccaagctgct
     1441 tggaatacag gaactgatcc aaatccaagt ggactatggg gaccaaatgc tgcgttcaac
     1501 tacactcgtt atgaatcaga agaaaataca aaattgatca acgatatcag ttcaagcaaa
     1561 gcatttgatg aagagtacca aaaagaagca tatcaaaaat ggcaacaata tgcatttgaa
     1621 gaagcatttg cgattccaac gttgttccgt aatgaagtat tgccagtcaa cgaccgtgtc
     1681 aaagactggg attggtctta tgatgtacca aacccatggg caaatgtttc tgttacagca
     1741 gattcacgtt cataatcact aaaaatgacc gaaaaagggc gatgtccttt ttcggttttt
     1801 tgatattttt ctgtttattt ctctaatatt caggtcaagg cgctgatttc atgacttctc
     1861 caataaacgg tgttcaaagt ccagtttctc ggtattaagt caaatttatg caaaaatatg
     1921 gaaagccatt ttcacaaaat tttttcttca tactcgaaac taaacgaatt tttcacaact
     1981 tctcgtcaat cactaggatt attaaagctt tacttacctt ttgaccgaac catttcaaat
     2041 ttgacaaaaa accagtataa taaggaagta tcgaaaaaat atccataaaa ggaatgtgga
     2101 aaatggacaa ccagctgaca aaagaactaa aagaaaacta taacatcgtt tttcacgatc
     2161 taaatttgct tgaacaagct tttacccatt catcctatgt gaatgagcat cgcaatctgc
     2221 aattatcgga taatgagcga cttgaatttt taggagatgc cgttttagaa ctgatggttt
     2281 ctcagtattt attccgttta tatcctcatt tgccagaagg aaaattgaca aaaacacgag
     2341 ctgcgatcgt tcgcgaagac agcttgtcga aatttgccaa agaatgtcac tttgatcaat
     2401 atgttttgtt gggcaaggga gaagagaatt caggaggacg tacgcgacca gcattgcttt
     2461 gcgacctatt cgaagctttt ttaggcgcgt tatatcttga ccagggattc gacacgaccc
     2521 atgcattcat cgaaaaagtg atttttccta aagtcaaagc aggtgctttt tcacatgaga
     2581 tggatcataa aacaaaacta caagaagtct tgcaaaaatc aggtgatgta tcaatcgaat
     2641 accgattgat caatgaagaa ggtccagctc atgaacgagt attttggatc gaagtttatg
     2701 tagatgatca attgattggc actggacaag ggaaatcgaa aaaattagca gaacaagctg
     2761 cggcggaaaa tgcattggca gcactgtaaa agtaagtgag ggaaagcttt gtatttgaaa
     2821 cgaattgaaa tagccggttt taaatcattt gcagacaaga cagtcattga ttttgaaaat
     2881 agcgtcacag cagtggttgg accaaatggc agcggaaaaa gcaatattac agaggctatc
     2941 cgctgggtat taggagaaca atctgctaaa agtctgcgag gcggaaaaat gccggatatc
     3001 atctttgccg gttccgatac ccgtaagcag ctgaatattg cagaagtcac agtgatttta
     3061 gacaatagtg atcattatct gccattggag tacaatgaga tcagtgtaac ccgccgttat
     3121 cgacggactg gggaaagcga gtttttcatc aataaacaaa gctgcagatt aaaagatatc
     3181 caagaattgt tcttagattc tggattagga aaagaatcgt tctcaatcat ttctcaagga
     3241 aaagtagaag cgattttcag tagtaaaccg gaagaccgtc gtgggatctt tgaagaagca
     3301 gctggtgtct tgaaatacaa gcagcggaaa aagaaagcag aacagaagct ttttgaaaca
     3361 gaagacaacc tcagccgcgt ccaagacatc atccacgaat tggaagaaca gttaactcct
     3421 ttggccgccc agagtgaggc agcaaaggag tttttacggc taaaagaaac actgactcaa
     3481 accgatgtct ctttgatggt tgctgaaatc aagacagcaa aaaaagattg ggacaacaaa
     3541 caagcacagc ttgcgaaatt caatctagaa ttaggcaaac tatctgagtc gatccaagaa
     3601 caagaatcca ttttggcgaa gcagcgtaaa gaaaatgcgc aagccgatcg tctgatcgaa
     3661 aaaaatcagc aagtattatt agatctttcg gaaaaactga agcagacaga aggacaaaaa
     3721 gatgttttgc aggagcggac aaagcataca caaaaaagct cgcaagaata tcaaacttca
     3781 ttagcagaag cacaaaaaaa ggttaaacat tttgaaaagc ttcaagaaag cttgatgaaa
     3841 gcagcagcag aaaaagaaac agagatccaa aaagctgaag caaatctcat aaaaacacag
     3901 caagaattag aaaaatacca aaaatcaacg aaagaattat tggcagaatt aagagatcaa
     3961 tatgttgatt tgatgcaaga acaagcagct gtaggaaacg aactgaagta tctagaacgt
     4021 caatatatac aagaaacagc aaaaagcaag cagacgttag ccaagcaatc ggaagtagaa
     4081 gcatcagtag accgattgat cttacaaaaa gaagaattga cacaaaagca ggcgcagcta
     4141 aaatcatctt taactgaaac aaaagagaag ttagaaatga tccaacaaaa cgggaaaaag
     4201 ttccaagaag cattagcaaa agaacagcct aaaatgtatc aattaatgaa tcaagtccag
     4261 cagctacgtg ctcgtaagaa aagccttcaa gaaatccaag aaaactattt tggtttttac
     4321 caaggggttc gattggtctt gcagcataaa cagcagcttt cgggtattgt cggagcagtg
     4381 gctgaactga tcgatgttcc tgcagatttc acgttagcta tcgaagcagc tttaggtggg
     4441 gcagcccagc atgtcatcgt tgaaaatgaa aaagatgctc ggcaagccat cacgtatttg
     4501 aaacagcaaa gaggaggaag agcaacattc cttccactga cgacaatcaa accaagacaa
     4561 ttaccggctc atatattgac acaagcagca gctgtagaag ggtttatagg gattgccagt
     4621 gaacaagtca gttatcccga tcaaatccaa actgtggttc aaaacctgct aggaacgatc
     4681 cttttagcca aagacttaac tagtgccaat gcaatcgcgc aaacgatccg ctatcaatat
     4741 cgagtggttt ccttagaagg tgatgtgatg aatgccggag gatccatgac aggtggagcg
     4801 aataaacgag gaaaccaagg cagtttgttt gtacaaaatc aagaattgaa acagttgact
     4861 agtgaatttg aagaagcaga taaacaactc caagcacaag aaaaaaaagt tcaggagctg
     4921 caacaagaaa cagctcgttt agccgaagaa caagaagttt tgcgtacacg aggcgaacaa
     4981 ttacgttttg aagaacaaga agcgacaaat cagctacaaa acatcataaa tgaacttgaa
     5041 cgttttgaaa aagaaaagca aatctcaact tttgagacac gtgaactgca gcagtttatc
     5101 gaagattacg aaaagcaaac gaacgaattg aaagacaaac aaacagatct tgaatcgcaa
     5161 cgacaaaaaa tcgacgaaga aatcaaatcg ttaagtcaag aaagcgacca gatggaagcc
     5221 agaagagcac aagtacaaag tcaaaaagca caagaacaag cagatcttgc tgtcttgaaa
     5281 gagcagttta atcatctgca gatccagctc cgcggtgccc gagtccaaaa agcagaggca
     5341 accgaacgtc aagaagcgat agaaaagcag ttggcgacat tgacagcaga cttttctgat
     5401 catgaagtca cagaagaaag tttggaaaaa caaattaacg aattatctgc tcagcgagaa
     5461 acattaaaag ccgagttggc aaaagccaaa gagcagcgag atagaaggca aaaggagatc
     5521 gataagcttg aagcagtctt ggcagagcgt aatcgtgagc aaaaagcacg actgtcggaa
     5581 caatccaaat tagaagtcca aaaagaccga gctgaaatga ttttagataa tcatttgacc
     5641 tatctgcagt cagaatatca gctgacattt gagaaagctt cccaagacta tcaagaaaca
     5701 accgatatcg aagacagtag aacaaaggtt tcatccttaa aagaacagat tgaaaaactg
     5761 ggaccagtaa acttaaattc aatcgaacaa tacgaacaag tcagtgaaag acatacattc
     5821 ttagcaacac agcgagatga tctgttagca gcgaaaaacc aattgtttga aacgatggat
     5881 gagatggatg atgaagtgcg gacaagattc aaagaagtat ttgaagctat ccgtcaagaa
     5941 ttcaaaattg tctttccaaa tatgtttggc ggcggtaaag ctgaattagt actgacggaa
     6001 ccaactgatt tgctgaaaac aggtattgag attgaagtac aacctcctgg caaaaaactg
     6061 caaagtctaa gtttgctttc tggaggagaa cgagcactta cagccatcgc gttgctcttt
     6121 tccattatcc gtgtctgtcc tgttccgttt tgtatcttag atgaggtaga agcagcgtta
     6181 gatgaagcca acgtgaaacg ttttggtcgt tacttgagcg atttccaaga tgacacacaa
     6241 tttatcgtag tcacacaccg caaaggaacg atggtcgcag cagatgtact gtacggagtg
     6301 acgatgcagg aatccggtgt atcaaaaatc gtttctgtac ggatggaaga tatcaatgaa
     6361 gaggcgaaaa tcaacgaaac gaaagtgtag gaacgaaaat gatcaaatta gtagcaatcg
     6421 atttggacgg tacattatta aatgaacaaa agctgatttc agatgagaat aaacaagcat
     6481 tagcacaagc aaaacagcaa ggggtcaaga tcgttctatg tacaggacgc cccttagctg
     6541 cgatggcgca ttatctgcaa gaattaggac tggtagatga aggtgactac agcatcactt
     6601 tcaacggcgg tttggtacaa aaaaatgata ctggtgaaat catggaaaag aaagtgatgg
     6661 aagtatcaga tatccaacgc ttatacaaac tggctcagca attggatctg ccactagatg
     6721 ttttgtctga caatgtggtt ttacagctgc ctagtgcccc aaggaagcaa tccttgtaca
     6781 atgtgttgaa taagctgctg caattccaac cagcggatat aagcgatatt acagatgaat
     6841 ttgtgcttaa taaggcagta atcgcttatg accaagaaga attagatcct aaaatcaaag
     6901 aaataccagc agaattccat gaaatgtatg agatcatcaa aacaagaagt atgcttttgg
     6961 aatttatgcc aaaaggtgtt acaaaagctt atggtatttc tttattggca aaagatcttg
     7021 gtttgaaaca agaagaaatc atggcgatcg gtgatgagga aaatgattta ccgatgatcc
     7081 aatatgctgg actaggcgta gcgatggaga atgctgtgcc tttcgtcaaa gaagcagcag
     7141 atttcgtgac agccagcaat gaagaaaatg gcgtagccaa agtgatccaa aaatttgtat
     7201 tagagtaggg ggagtcaaat gggatttttt gataaaatca agcgtgcttt tactggcgaa
     7261 gagaaaacag aagaagttga agtacaggag aagtacgaca agggtttaga aaagacgcgt
     7321 aaaacatttg gtgaacggat gaatgagttg tttgccaatt ttcgaacagt cgatgaagac
     7381 ttttttgaag aattagaaga aacacttatc ggtgcagatg taggttttga aacagcgata
     7441 cgaatcaccg aagcattacg tcaagaagtg aaactcagaa atgcgaaaaa atcggcagaa
     7501 gtccaaaatg cgatcatcga gaaacttgtg gatctctatg aagcggaagg aatcaatgaa
     7561 gtaaatgaac taaatatcca agaagacgga ctaacagtta ttttgtttgt cggtgttaat
     7621 ggtgtaggga aaacaacaag tattggtaaa cttgcccatc agttcaaaaa cgaaggtaaa
     7681 aaagtattga tggcagcagc agataccttc cgcgctggag caatcgacca gttagttgtc
     7741 tggggcgaac gcgctggtgt tgaagttgtt cgtggcaatg caggaggcga tccagcagct
     7801 gtcgtattcg atgctttgga aagagcaaag acagagcagg cagatgtttt actagttgat
     7861 actgcaggcc gactgcaaaa taaagtgaac ttgatgaacg aattagaaaa aataaaacga
     7921 gtaatccagc gggaattacc agaagcaccc caagaaacac ttcttgtatt agatgcaacc
     7981 actggtcaaa acgcgatggt tcaagcaaaa caattcaaag aaacaacaga tgtgaccggt
     8041 cttgttttga caaaattaga tggtacagca aagggcggta tcgtacttgc tatccgtaat
     8101 gaattgcatt taccagtgaa attggtcggt cttggtgaag gaatcgatga cttggagccg
     8161 tttgatccaa atgattttgt cgttggattg ttcaaaggat tactaaaaga agaataaccc
     8221 atgtctaaaa agcaggagct gtgacaaaag ttgcagctcc ttgtttgaat gattgttttt
     8281 aacatagctg tgtttttgat gccttcattt ttatacttat ttgtaagcgg ttctcaaaca
     8341 atttcgttct ttttcttaga ctttttgatt ataattagat tcatatgaat tggaggtcac
     8401 ttaatgatga attttaagca attattattg catgtcaatg cgcgcccttt tatcgaccaa
     8461 gctcgatttg gtatagaacg ggaaggacag cgggttgatc ttgcaggaaa tctagcaaaa
     8521 accgatcatc cagcaatctt tggcgatcga tcctatcacc cctatatcca aacagatttt
     8581 agcgaaacac aaacagagat gatcacccct gttaccgatt ctattcccga attatttcag
     8641 tatctcgctg ctgtttatga tgtgactgct cgttctatac cgaaagaaga gatgatctgg
     8701 ccattaagta tgccacctgc cttaccggaa aaagacgaag agatcattat tgcaaaatta
     8761 aaaaatttcg aagatgtctt gtatcgacgt tatttagcaa aagaatacgg gaagcgaaaa
     8821 cagatggtaa gcggtattca tttcaatttt gaatttggcg atgagttgct aagaacattg
     8881 ttcagccatc aggaagaatt tcaagatttt tccgaattca aaacagaact ttatttgaaa
     8941 acagcgagaa actttatgcg ctatcgctgg atgatcactt atttattcgg tgcttcacca
     9001 atgagtgaga agaactactt tttagatgaa tcacatccgc aagaacctgt tcgcagtatt
     9061 cgcaacagtg cgctgggcta tacgaatcat ccaaatgtga aagtttccta tgcttctatg
     9121 aaacagtatt tagcagatat cgagcgaatg atcgaagaag ggaaactttc ggaggagaaa
     9181 gaattttata caccgcttcg tttccgaggc ggaaagaaag tcgcagattt agcaacaaca
     9241 ggtgttcgtt atattgaatt gcggaatatc gatttgaatc cttatgcaag attgggtatc
     9301 aatccagagc aagttcggtt cttacaatta ttcctgatgt acatgttatg gacagaagaa
     9361 aaagaagact gtgaccaatg ggtagcagaa ggtacgactc gaaataacaa agtagcacta
     9421 gaacaaccat cagatcaaac agaatttcat caagaaggta gagaaattct tgaaggaatg
     9481 aagcaaatgc tggttgaatt ggattggttg gattctcttt atttagtaga ggaagcattg
     9541 actcaaatgg atcatcctga acaaacgtta gcagcgaaac tctatcaaga agcacagcta
     9601 tcgagtcagc aagaagttgc tgtggcattg ggacatcaat attataaaga aagccatgaa
     9661 cgtccctatc agttggccgg ttttcgcgaa atggaacttt ctactcagat atttatgttc
     9721 gatgccatcc aaaaaggtgt ccaagtcaaa gtattagatg agtcggatca atttttgcgt
     9781 ctgcaattcc aagaccatgt agaatatgtg aaaaatgcaa acatgacaag taaggacagc
     9841 tatatcgtcc cacttatcat ggaaaacaaa acagtaacga aaaaagtctt aaaagaagct
     9901 gggttccggg taccaggagg cgcagaattt tcatccatgg aagaagcggt aaaagcttat
     9961 ccgagatttg ccgagcaggc atttgtgatc aaacctaaat caaccaatta cgggttaggt
    10021 atcacgattt tcaaggaagg agctagtctg gaagattatc aagcaggttt agccattgct
    10081 tttcgtgaag acagttcggt tttagtagaa gaatttatgc cgggaacgga atatcgtttc
    10141 tttgtgatcg acggagaagt ccaagccatc atgttgcgag tccctgctaa tgttattggt
    10201 gacagtatcc gaacagtgaa agaacttgtt gaagaaaaaa atagtgaccc tttgcgtgga
    10261 acgaatcatc gtgcaccttt agaattgatc caattaggtg aattagaaca attgatgttg
    10321 aaagaacaag ggttgacgat cgaatcagtt ccccaagcca atcaaattgt ttatctaagg
    10381 gagaactcaa atatcagtac aggtggtgat tcgatcgata tgactgatga attttctgaa
    10441 gcttacaaaa aaatcgccgt ttctgcggta gaagcactag gagctaagat tagtggtatc
    10501 gatttgatta taccagataa agaaatcgat cctacaactg ataaaaaagc atatgggatc
    10561 atcgaagcaa atttcaatcc agccatgcat atgcatgttt atccttttgc aggaaaaggc
    10621 agaagattga cgatgaatgt attgaaattg ttatatcctg aagtatttta aaagaaaaag
    10681 cttttgacag attgtcctat ttgatgtcaa tctgatcaaa agcttttttt gcatgtaaaa
    10741 atttatgtgt tttttcgttt taaaataaac gatcccagaa gctttttttc ttttttggtt
    10801 tttctttttc agctggcgaa gagttttctt ctgggtattt tttttcgata tcaatcacag
    10861 gttcatttac tgcttctttt gctgttaaga gcaatccgaa ttcctcagga tttgcagtga
    10921 cgtaatcgtt gactacagtg aaacggctat tgtttttcgt tgctagctgg atatattggt
    10981 tttggacaga aaggggtaga gccccattca agagtatgga agcatctgga tgttttttga
    11041 gttcttttaa aaagttttct ttgttttttg gttggatcat ttcagcaaca gtcatactaa
    11101 gatagcagcg ttccctgaat gtccctaaat atttatgctg ttcttcaggg ttcactaaag
    11161 gtgtaccata aagtccctta tccaaatggc tttttacatc atcttgtgcc ataaaaaata
    11221 ccctccttct tctctttgtc tttcttacga ttatagcata ttcccaataa tacctaaaac
    11281 atatgaaaaa gcggttgctt ttgttcaacg attcacttaa aataagaatg aaaatcattc
    11341 tcaattagaa aggtggattg gatgcgctac ggacgactag tagcattatt agttatttta
    11401 agtagtattt cattgttcat cggagtatcg aatgtacaat tgtcagaact gctccagtta
    11461 gatgggcaaa gcttacaaat cttgctagtg actcgtttgc cacgaacgat ttgtttgatc
    11521 cttgtgggag cgaccagtag tatttgtggg ttgatcatgc aacatttgac ccaaaataaa
    11581 tttgtttcac caacgactgc gggcacgatg gatagtgcgc gtttaggtat tttagtggct
    11641 atgattttcc tacctggtgc atccttgatt gtccgatcct tgacagcatt ttgctttgct
    11701 tttgcaggaa cattgctttt tttatccctt acgcgattgt tcctccagaa aaatcaattg
    11761 atgcttccgt tgattggagt catgttaggg aatatcattg gttcagttgc tacttttttt
    11821 gcttatcaat tccagttggt acaaaatatg acttcatggc ttcaagggaa ttttgcgact
    11881 gtgatacgag gaaattatga gttattgtat gctgttgttc cattgttgct cttggtttgg
    11941 ctatttgctt accgatttac gatcattggt ctgggcgaat cgtttgcagt aaatctggga
    12001 atagattacc agaagatgca gtttttaggc attggcttag tatcattggc tagtgcagtc
    12061 atgttgatca tggtaggaag cattcctttt atcggagtga tcattccgaa tcttgtctct
    12121 agaatatatg gagatcaagt gcacaaaaca attggcgtaa ctgctttagc aggtagtttg
    12181 ttcttagtat tttgcgatct tgtcgctcgc gtgttgattt ttccttatga aataccagtc
    12241 agtgtgatcg ttggaatcat cggtggggct atcttccttt atcttctgat aaggggacga
    12301 cgatatgctt aaaaaaaagc catctatttt tattggtatg cttgttcttg ttttatttgt
    12361 tacaggaatg tacttgacga tccatacata tggaaactgg cattttgcat gtgcattgag
    12421 gagtaagaaa atttttgcat ttatccttgt ctcgctagct gtcagcagtg ccacaatcag
    12481 ctttcagaca attacgcata accagttttt gactccttca gtattgggac ttgagtcgtt
    12541 atatgtcctt gtccaaacgg tccttttctt ctttatcgga ggagtgacga tgcttcagca
    12601 gacaggtaca gtttttttct tattgaacgt tgggctgatg gtcgggctga gtctattgtt
    12661 atttttcttt cttttgaaaa aaatgagagc gaatcttttt ttattactga tgtcagggat
    12721 gattttaggt acgctttttg gtagtgtcag taccttttta caagtcatca tggatccgaa
    12781 tgaatatgat ttgcttcaag gcagattatt tgcaagcttt ggcaatatcc agagtcagta
    12841 tcttttgcct gcttctttga tcattatcgg ctgctggtac ctgttatttc gatatcgaca
    12901 tgtgctagac gttttccatc tcggaaatga acaagcagta aacctcggga tagacacaga
    12961 tcgttttgaa tttttgattt tatgttgtgt cagtcttttg acagggacat caacggctct
    13021 tgtgggtcca gttacttttt tagggtttat tgtcgcaaat atcagttatc gtgtcttttc
    13081 tacttatcgt catggtcagc tatttatcgg aagctttctg gtagctatgc tgtttctgac
    13141 aggaggacag ctcgcagtag agcagatttt cggctggaat acaacagtga gtgtcgtcgt
    13201 tgaatttgtc ggaggaattt attttgtcac aaaattgatt cgcgaaagga agagtatcct
    13261 atgattgatt tacaaaaggt caataaactg taccatggaa aatcagtggt taaagatgta
    13321 cagttaacga ttcctgaaaa gaagttgact gcttttatcg gtccaaatgg tgctggaaag
    13381 tcaacggtgt tgtcgatgat cagtcgtttg ataccaaaag atacaggtga aatctattta
    13441 gaccataacg aagtaaaggc ttggaaatcc aatgaattag ccaaaaaatt atcgatccta
    13501 cgacaatcga atgaaataaa tgtccaaatc accgtgaaag aattagtaga atttggacga
    13561 tttccttata cgaaaggaaa attgacgaca aaagacgagg aaatcgttca ggaatcactg
    13621 gaacacattg ggttagaaga aatagcggat caatcgattg acactctttc aggcggtcaa
    13681 ctccaacgtg cgtatattgc aatggtgcta gcgcaagaca cggattatat tttactggat
    13741 gaacctttga acaatctaga tatgaatttt gcggttcaaa tcatgcagat tttaaaaaat
    13801 ttagtacaag aaatcgggaa aacaattgtt attgttcttc atgatatcaa ctttgctgca
    13861 agttatgcag acgaaattgt tgcaatgaaa gatggacagt tatttacgca aggaacgacc
    13921 caagaaatga taaaaaaaga tgtattggat gaattatacg aaatggacat acggatttgt
    13981 gagattgaag gccgcagatt ctgtctttat ttctaaaact aacattagga gagaagagat
    14041 gaaaaaatta gtagtaggta tcttgattct agcatcattt ggtttagcag catgtggaaa
    14101 tagcaacaac accagtcagg cagacacaaa aaaaagcagc acacaaactg aaactacatt
    14161 gacgataaca gatagtaatg gagaccaaat cgaggtgcca aataatccag aaaaagtcgt
    14221 cgtattcgac aatggttctt tagatacgat ggatgctctt ggtgttggag ataaggtagt
    14281 tggagcagct acaagcagcc ttcctgagta tctttcatcc tataaaaaag tagaatcagc
    14341 aggtggaata aaagaaccag acttagaaaa aattaatcag cttcagccag atctaatcat
    14401 catttctggc cgacaaagag attttcaaaa agatctaagt caaattgctc cgaccatttt
    14461 cctttcttta gatgcgaaaa atccatggga atctttccag caaaatgtca ctgctttagg
    14521 ggagatcttt ggtaagcaag aagaagctaa aactcaatta gaggaattat ctagtgcaat
    14581 cgatcagacg aaaaagaaag cagaagctac tgacaaaaaa gcactagtca cacttgtgaa
    14641 tgaagggcaa ttatcagcct acggatctgg ttctagattc ggtttcatcc atgatttatt
    14701 tggctttgaa caagcagatg atcaaatcga agcatccact cacggtcaaa gtgtttctta
    14761 tgaatatgtg ctggaaaaaa atccggatat cttatttgta gtagacagaa caaaagctat
    14821 tggtggagac gacagcaaag atgatatttc tgccaatgaa ctggtagcac aaacgaatgc
    14881 tggtaaaaat cagcagatca tctcccttga accagatgtc tggtatttaa gcgggggcgg
    14941 tttagaatca atgaaactga tgatcgaaga tgtgaatcaa gcatttaaat agcataaata
    15001 acagaggatt aaactctcat actatgtaac aataatgttt cttacattct taaatagcaa
    15061 gagcctatcc tcaaagaagt tatcaaaaac catccgtaaa atcgtattga tgattttacg
    15121 gatggttttt atttatttga gaaatctttt ttcaacgtga attcattatc tacatcatac
    15181 gggttgattc tagaatgggg agtggcaaaa aatagtgtga tccatttttt cagcatcaag
    15241 atcgcctcct ttgatttgaa tcaaaggtac aaagcgaaac ttagataaaa cttaaattta
    15301 gatattttta ttttgtaccg atctcttctt taaacgatgt tccatctgct gcttctcggc
    15361 aataagtcca ctagactaga aaatatgaga agctattttc tgtccagcgt tcttattact
    15421 caaaacaaat cgcagttgtc acaatctctt ctaaacgatg ttccatctgc tgcttctcgg
    15481 caataagccc actagactag aaaatatgag aagctatttt ctgtccagcg ttcttattac
    15541 tcaaagcaaa tcgcagttgt cacaatctct tctaaacaat gttcaatcag ctgaccttcg
    15601 gtattagctc aaagcactga tttcacaacc tctatttagg catgtgtctc agcaagcggt
    15661 tgatagttga tgatctgcat ttttcgataa aaatcggcgg gaagcttact ccaccgtttt
    15721 agtaattgat agaaataact ctcttctgct ttgattttat actcgcttaa tatcaatcca
    15781 aaactattcg ttttttttga agctaatttt ttataaatat ccaatgcttt ggttttatct
    15841 tcattgacaa agagtgtttt tacttcaata taagaaccct cgatattttg tgtttcttcg
    15901 ataaaataga tgttttttat atattccttc atagtgattc ctccaaagaa gtcttttatt
    15961 tgataagttt actctaccga agagttgtta ataatccgtg aacaaaaagt aattcttttt
    16021 ccaatagttg ttaaaggttt tttatttttt atagtatttt ttgttattta agaaaggaat
    16081 aaggttaaac aaataacagg ttgctttttg ggtctttttc cgttcaagaa actgaacgaa
    16141 gaaaagggaa agttgtctct tttgtgataa gagaaatcat aataaacgaa tgacttactt
    16201 tccaataaat tgagaacagt cagaaccaga caaattagtt gcatctgatg aataaagtga
    16261 ttattctatg acatgaggtg atacagatga aattagaagt gacaaaagaa gcacaagaag
    16321 tattgaagaa taaattagaa gcagacgatc aacttttatt agatatcgaa aacggtgacg
    16381 gtccatttgc agaaagccaa gtcagttgcc aattggatac ggcatttcga ttgatcattg
    16441 tcaaaaaaga tacacaaaca gatctaagtc tttattctgt agtggctgat acaccagttg
    16501 gaccaatcaa aatcaaagac agtgcaatac tttacatgga tgatccatcc acacttgctt
    16561 tagaaccaac ttataatagt ttacaattaa aaggaccaag cggcttgaga aaaggcaact
    16621 tgcaagttgt tcgaaaagac tagagggata aaatgggaaa attggcgatc atcagcgacc
    16681 tacatgtgga catcaataaa ttcggcgaat cagagctgat gcagctttgg caagttttgc
    16741 aaaagcacaa gatcactcgg cttcatctag ccggagatac ggctaataaa gtagaccgtt
    16801 gcctagctgt tgtcgaattt ttcgtcaata aaggattatc tacgacattt catttcggca
    16861 atcacgagtt ggcagatgtg cccaatgaac agatgatgga ccattttcca gacccacatt
    16921 ttttaaatga acggtatatt gctttaaatg agcagaccgt tcttttaggg atgaatggct
    16981 ggtacgacta tcagttttcc gaattgaaag attacgaggc aatcgtacga atgaagcgtt
    17041 tgtattggta tgatcggttc atccagcgtg ggaaaacaga tctcgaggtc aatgcagaaa
    17101 tgcttgcagc tgcaaaaaat ttgctagacc agctggaagc aaaaaaactt gaggtgattt
    17161 tatccactca tttcgttcct aaacgggcat ttatcatgta tcaatctgct ccttatgagc
    17221 gttggaacaa attaaatgca tttttaggat cagaatcatt cggagaatta cttgaccgtt
    17281 attcaaatat caaacaagta gtttttggcc atacgcatcg tcgctttgaa gataaatcca
    17341 tcggtcacac gatttacagc tgcagacctt ttggttatta ttatgaatgg cagctgaccc
    17401 gagattttgt cttgaaagaa cagttgctag acagctatga tcctatgaaa ttacgtgtcc
    17461 tcttgcgtgc ccatcaccca gcttttcagg cctatcaaac acaacatttg caagaggaat
    17521 ttgaacaagc gatgacaatc gttccgtatt gagacagcat tagtaatgtg taaaagaaaa
    17581 taccttgtaa aacataagga taagtaagag cagtagatcc atttatcgtg gatatgctgc
    17641 tttttttgcg gaaaataatc agcgaatgtt tatttgatcg gatgatttgt aactcgcaga
    17701 gtactagatg caagcgtgta ttcttttttt gaacgataat cacaaaaaaa aatataatat
    17761 acatttttta tttaattata attaatattg attgaagtct aggcagtcaa gtcgagagt
//
LOCUS       DAFELK010000057        17034 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFELK010000057
VERSION     DAFELK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.059"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            226..894
                     /locus_tag="LP433_002262"
     CDS             226..894
                     /locus_tag="LP433_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBL2006397.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1324)
                     /locus_tag="LP433_002263"
     CDS             complement(1094..1324)
                     /locus_tag="LP433_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006398.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1451..2833)
                     /locus_tag="LP433_002264"
     CDS             complement(1451..2833)
                     /locus_tag="LP433_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL2006399.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="LP433_002265"
     CDS             complement(2989..4176)
                     /locus_tag="LP433_002265"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBL2006400.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="LP433_002266"
     CDS             complement(4183..5214)
                     /locus_tag="LP433_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL2006401.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5230..6684)
                     /locus_tag="LP433_002267"
     CDS             complement(5230..6684)
                     /locus_tag="LP433_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2006402.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            6859..7764
                     /locus_tag="LP433_002268"
     CDS             6859..7764
                     /locus_tag="LP433_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL2006403.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="LP433_002269"
     CDS             7855..8532
                     /locus_tag="LP433_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL2006404.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8529..8699
                     /locus_tag="LP433_002270"
     CDS             8529..8699
                     /locus_tag="LP433_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006405.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8784..9680
                     /locus_tag="LP433_002271"
     CDS             8784..9680
                     /locus_tag="LP433_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2006406.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9735..11105)
                     /locus_tag="LP433_002272"
     CDS             complement(9735..11105)
                     /locus_tag="LP433_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2006407.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEILYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11343..12089
                     /locus_tag="LP433_002273"
     CDS             11343..12089
                     /locus_tag="LP433_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL2006408.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12086..12925
                     /locus_tag="LP433_002274"
     CDS             12086..12925
                     /locus_tag="LP433_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL2006409.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12926..13876
                     /locus_tag="LP433_002275"
     CDS             12926..13876
                     /locus_tag="LP433_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL2006410.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDTHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14017..14769
                     /locus_tag="LP433_002276"
     CDS             14017..14769
                     /locus_tag="LP433_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006411.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14788..15939
                     /gene="queG"
                     /locus_tag="LP433_002277"
     CDS             14788..15939
                     /gene="queG"
                     /locus_tag="LP433_002277"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBL2006412.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            16323..16931
                     /locus_tag="LP433_002278"
     CDS             16323..16931
                     /locus_tag="LP433_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2006413.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         5561 a         3171 c         3399 g         4903 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgctag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt tcatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctacattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttag acaattattt gctacaataa gaatatgaag cgtttgataa cgctattata
     8761 cataaaaatt ggtggtgaaa aaaatgtatg atgaaaatga gtggggagaa aatgttcgga
     8821 tgacccgaag aagacagcaa aaacaggcag ctcgtaagcg gatgatcatg attggggcag
     8881 cagttgccgt gtttttgatc atagcaggag gagttgcggg tctatatttt catggaaaaa
     8941 attcgtcaga agcgaaaagt acgaccataa cggaaacaac gacaaagaaa acagagacga
     9001 aacaaacaag tgagtcatca actaaaacaa aagagacaca aacttctgaa gaaaaaacag
     9061 caaatggttt gccagagcaa cttcaagcaa tcgtaaatga ttattcgaaa aagatcgaag
     9121 aaaagacgcc tgcattgatt gaagaatacc agacagaaat tcagggaaat caagagggaa
     9181 tagctggttt atcagcagtt gctaaccaaa aagcacgtga gcttcaagca atctccgacg
     9241 aagggatcag aaaattacgt gcagcgtatc aggcagcaga aaataaagac ggtgtagact
     9301 tagatacttt gatcaatcaa ttatcggcta attatacgaa tcatgtcgct aagatttccg
     9361 atatttattt gcagactagc gcctctcttc aagcagagtc aacaagcaca caagacacaa
     9421 catcttctga ttctgagaca gcagagtcgg tagaagcttc tgaaatgcaa gctcgaacaa
     9481 cacaagacac aacagattcc tctgaaacta ataccaacag cgcgacttca caggctgcga
     9541 caaccgtagt tttggaagga gaaggtccaa atcaaatagc cgaacgaact ggcgtaccag
     9601 tagaaacgat cttgtcgctg aatgggatga gcatggagaa ttatttcctg actcccggtg
     9661 agacgctaaa attgaattga taaaagcaat aaaaaagaac gaagcttcca ctaaggtgaa
     9721 gcttcgttct ttttttattt tccggttctt ttttcgcgta caaagtaatg gatcgtcatg
     9781 taaagcaaga aaacgagtcc aataatcaat gagattctcg tttcaggatt gataaacatg
     9841 aaaatcaata cgatagctaa aaaagcaagt gtcacataat tcgtataagg agatagtggc
     9901 attttaaaag gatgatcatg cattttatct gcgtgcttct ttttgaagcg aatctcgctg
     9961 atcaaaatca ctacccaagg aaccatacca ggcaaaatac ttgagctgta tacgaaaacg
    10021 aaaatatttt ctgactggtt gatgaacatt ggtagaagat aatttaagat cagaccaatt
    10081 aagattccac ctgagattgc tacgacagga taaaaaggcg caccgtgacg agatagtttc
    10141 agaaattttt tagacatctt tccatttatg gcaagtgtat agaccatacg acttgcgctg
    10201 aaaatccctg aattgcaacc tgataatgcc gctgtaatca cgacaaaatt aatcagtcct
    10261 gcagcaaatg taatgccgac tttagaaaaa gtttgtacaa aaggtgaacc aatctcactc
    10321 aattgattcc acggatagat actcacaatg ataaaaatag caccaatata aaaaatcaag
    10381 attcgaccga tagtggactg gacagcttca atgatcgtct ttttaggatt ctctgcttca
    10441 ccagcagtca ttccgatcag ttcgattcct tgataggaag caacaacgat cgataatgca
    10501 aagaaaaatc ctttgacgcc tccagtgaag aatccaccat ttttccaaag atttgaaatc
    10561 cctactgcct gaccatgatt accaaatcca aataagatta ccccaagacc tgcaatgatc
    10621 atcaaaatga tcgttatgac tttgatgatc gaaaaccaaa attctaattc gccaaacgcc
    10681 ttgacagaaa taagatttgc cagcataaga aacaagacga caatgattcc gggaataatt
    10741 gccggcaaat caggccacca ataattcata taagatccta cagcaatcac ttcacttatt
    10801 cctacgacaa tatattgaaa aatattactc caagcggtca agtagccagc cacaggatgg
    10861 atgtactcgc tcgcgtaatt tgcaaaagaa ccagtcgaag gatcaacgta aagtatttcg
    10921 cctaaagcac gcataatcaa atacaaaaag aatcctgcaa tcgcataggc tcccatcact
    10981 gagggccctg tccaacgtat ggttgaggag gcacccataa acagaccgac accgatcgtt
    11041 ccacctagtg cgatcatttg gatatgacgg gcactaagac ttcgagttaa cttttcttct
    11101 tccatacaaa aactcctttc gttgttgagt caacaagaaa aaataatcaa acgtttcaac
    11161 acatgttttt cattattagg ttagccttat tgaactcttg atgtgattct acagaaaatt
    11221 ttcataaaat gcgaggaaaa ttcgaaaaaa actttttcat cattctactt gaaaatgctt
    11281 tccattttag ttaaactata tttaaataaa aagttaggta aacctaaaaa ggagtgtaag
    11341 atttggaacg tacggccatt gtaattcaag acctttcagc cgcttatcaa gggaaaactg
    11401 ttttgaaaac tatcaacttg acgataaatc cacaaaaaat taccggtatt atcggaccaa
    11461 acggtgcagg aaaatcaaca tttatgaaat ctttgctaga gttgatacca gctactactg
    11521 gtaaagtcac cttttctgga cagtcggtaa actcagtccg taaaaaaata gcctacgtgg
    11581 aacagcgaag tgaattggat ctttcctttc caattgatgt attaggcgtt gtacttttag
    11641 gaacatatcc atctttacga attggacaaa gacctgggaa aaaagaaaaa gaacgtgcaa
    11701 gacaagcttt gaaaaaagta gggatggaag aatatgccaa aagacagatc agcgaactat
    11761 cgggtggaca gcttcagaga gtttttattg caagagctct agcccaagga gcagaatgga
    11821 tctttttaga tgaaccattc gtagggattg atgcgttaag tgaacgaaag atctttgaca
    11881 tcttgcagga attgaagaat tcaggaaaaa cgattttgat cgtccatcat gatcttcata
    11941 aagtagaaga atatttcgat gaggttattc ttttaaataa acagctgatc gcttccggtc
    12001 cagtacaaga agtctttaca tcgaagaacc ttcaattggc ctatggtgag atcatcagac
    12061 atttagtaaa aggaggagag aaaaaatgat ccaatccttt attgatggat taatgaatta
    12121 tcaattcctg caatacgctt tggtcacttc catgcttgta ggacttgctt ctggagtcat
    12181 cggttctttt attattttac gagggatgtc tttgatggga gacgctatct ctcacgcagt
    12241 tcttccaggt gtagccattt cttatatgtt tggttttagt tacatctttg gagccactgc
    12301 ttttgggatg ctaacagcag cagtgattgg tttcgtgact cagcggagcc gattgaaaaa
    12361 tgatacagcg attggaattg tctttagctc cttttttgca ttagggatta tcttgatttc
    12421 atatgcccag agtgcgacag atttgtatca tattttattt gggaatgtct tagctgttag
    12481 ggaaagcgat ttgttgctga cagcactcgt tagtggaatc gtcttgatat ttgtcttttt
    12541 cttttataaa gaattgaaga tcacatcatt cgatccgaca atggcaaaag cttatgggct
    12601 gaacacatcg ctgatccatt atcttttgat gttctttttg acattagtgg ctgtagtcag
    12661 tttacagaca gtaggaacaa tcttggtgat tgccatgttg atcacaccag ccgccacggc
    12721 ttacttgcta acgaaccatt tactgaaaat gatcattaca gctgcaggaa tcggtatgct
    12781 aagtgcagtt gtcggtgtgt ttttcagtta tagttacaat tggccatcag gagctacgat
    12841 cgtgttagca tgtaccgcat tttttatcct tgctttttta ttttctccaa caaaaggaat
    12901 tttatttcag aaaggaagca gatagatgaa aacaaaaaaa tcactctttt taatcttggc
    12961 agttagtttc ttggtattag ccggttgcgg aaagcaggct tctgaccaag cggatgaagg
    13021 aagtaaagaa aagttgtcag tcgtggctac caattcgatc ttggcggaca tggcaaaaga
    13081 ggtcggaaca gatcaaatag atacccacag tatcgtacca gtcggaacag atccgcatga
    13141 atatgaagta ctaccagaag acatcaaaaa ggcaagcgat gcagatgtta ttttatacaa
    13201 cggtttgaat cttgaaacag gtaacagctg gttcgataac ttgatggaaa cggctaaaaa
    13261 agaagaagga aaagattatt ttgcagttag caaaaatgta gaacctcttt atttaactag
    13321 cggtgaagaa catacaaaag cagatcccca tgcttggcta gacctatcta acggaataaa
    13381 atatgtggag gaaatcgcac gtatattctc tgaaaaagat gcagaaaatg cgacactcta
    13441 taaaaaaaat gcagaagcat atgtggaaaa actaaaagaa ttagatacac aagcgaagga
    13501 aagttttgct tctatcgaag agaacaaaaa attattagta acaagtgaag gggcattcaa
    13561 gtatttttca cgagcatatg atttgccagc agcttatata tgggagatca atacagaaag
    13621 tcaaggtacg cctgatcaaa tgaaagcgat cattgatcag ataagagcaa aagaagtacc
    13681 ggttttattc gtggaaacca gtgtagactc aagaagcatg gaacgggtag caaaagaaac
    13741 gggtttgaaa atctatgata aactgttcac tgattccata gcaaaagaag gagaacaagg
    13801 agattcttac tatcagatga tgaaatggaa tattgaaacg atccatgaag gtttgtcaca
    13861 aacaaaagaa agctgaaaag tgcaaggtct agcttgagga gcagaccttg cattttttat
    13921 aagagatatg aaaaaaaatt atgctgtttt tcgtcgtaca gatacctttt ttgaagaaat
    13981 tccgttatag ttagagtaag gaaggaaggt gtggctatga attttacacg taaagataaa
    14041 tatacgatta aagaagaagt ctttcgattg atcagccagc aggaaaatac cgacaaggat
    14101 caagaccttc aatttcttga agcagaatta gctaaattat tcatagcaaa tcaaaatgag
    14161 acaacagaac cagatgaaga gctgtacata ggcaaatggt tgtttgatga atttcagcct
    14221 ttagatgaaa ataccggtat cggttatttt gtgttccttt ctccagtcgg cttcacacct
    14281 ggcgtattag ttaaacaaaa cgacgaaata accgtcaaag catggcctgc attattttca
    14341 gtcatcaaag cagaaggagt aatcaaaaag atccagtcgg cctattataa aagtcaattt
    14401 attgccaaca gcaaattaat gaatatgttt tataatcgtc tagtagaaat tgctaggcct
    14461 gggaaaatcc cgcaaacatt cacgtacaca cagcaaaaaa atctctatga agaagtattg
    14521 tattcccgcg atctgtctga gttttcgcca tgggaagagg taaggctcca tgaactgtta
    14581 agtacaaaac cagtttcatt gaattttttt aatgcattag ataacaaaag aaaattaatt
    14641 tcaacaaatt attgggaagt atttgctgca agaaaaaaat ggatggaaga aaagaagatt
    14701 gccgatcagc agatccagtt tgtccagctg aaaaaagaaa aactatatta tgggttatac
    14761 agccgttaac agcaagcgag gaagaccatg acattaaaag aagaaatcat acaagaaagc
    14821 aaacgattag gaattgacaa aatcgggttc accacggcgg aaccttttga ttcattaaaa
    14881 gaatcgttgg aagaacaaaa agcagctggc catacttctg gctttgaaca tccaaatatc
    14941 gatgagcgtc tttatccaga aatgacattt gatcagccga aatcgatcat ttccattgca
    15001 cttgcgtatc ctactaggat ccatgaagaa gtgcctaggg atgaaaaacg cgggcagttt
    15061 gctcgtgctt cttgggggat cgattaccat gatatactca gagaccgttt gaaccgattg
    15121 atcgaattca tccaaacaag agcagaaaaa tggcaaaaag aagaggaatg gcgtctagct
    15181 ccgcaagtag atactggaga actgatcgat gtcgctgtag cacagcgagc tggtttagga
    15241 tttattggac gaaacggatt gttgatcact gaagagttcg gttcatttgt ctatcttggt
    15301 gagatcgtta ctaatattgt atttgagcct gataaaccag gagaatttgg ttgcggtgac
    15361 tgtatgcgct gcgtgactgc ttgtccgaca aaagcattgc ttggtgacgg aagaatgaat
    15421 gcccagcgat gtttgtctta tcaaactcag acaaaaggga tgatgccgga agaatatcgt
    15481 aaaaaaatgc gaaatgtcat ttatggatgt gatatctgcc agttagtctg cccttacaat
    15541 caaggaaaag attttcattt tcatgaagag atggaaccaa aagtagacga aatatatcca
    15601 aaattaaagc caatgctttc gatgtctaat aaagacttca aacagcaatt tgggcattta
    15661 gctggttcat ggcgtgggaa gaaacctttg cagagaaacg cattgattgc tttagctaat
    15721 ctaggtgatc gaacggcatt gcctgagatt tcagaatgtt taacagatgt ccgccctgtc
    15781 atcagaggaa cagcagcttg ggctattgga cgtctaggaa caaaagaacc ggaaaaatgg
    15841 cttgatgtat tagatgaaat attagctaaa gaaacagaag aagtcgttat aaacgaattg
    15901 gaacatgccc agaaattatt gcggagaaag ttaaaataaa aaaatagtta acattattca
    15961 aagtttttgt ccagtaattg ttgtaacaat tactggtttt tttgtatttt ttacattttt
    16021 ttaagagaat ttgataaaaa tcaaaaattt ttttgctttt ttttatggat tattgcagtg
    16081 aatgttacag aatctgcgtt tttcattcaa aaataaaaaa acatagaaaa acgattactt
    16141 tgcttataca acaaggcttt tatggttttg tatcaaaaaa atatttgttt aaatgttaca
    16201 aatattaaat aattcgttat tttgtcatta aatgtcatgt ttcttttacc tatgaaatat
    16261 ttctaaatga taaagttaat agcgtcgaaa gaataaaaaa cggagaaaaa aaggagttta
    16321 atatgaattc atttaagaaa attgttttag gtacaacttt tgctgctggt gctactgcaa
    16381 tgtttgtagg aactacaaat gctcacgctg atgaagttta tacagtaaaa tcaggtgatt
    16441 cattatctaa gatctcacaa aaatttgcag gagacaactc aatgatcgat gcaattgctg
    16501 aaaaaaattc gatcgcaaac atcaaccgca tttatgttgg tgaacaatta acaatcccaa
    16561 cttcaaatga ttcttcagca acaacagaaa acaaaacaac agaaaataca gcatctacaa
    16621 ctgaaacagc aacgcaagaa catacatacg ttgcacctgt tgaaacagtt gaagtagctc
    16681 ctgctgcccc agctgctgca acagcgccaa cttcaagctc tgcaaaagaa tggatcgcac
    16741 aaaaagaatc aggcggttca tacacagcta ctaacggacg ttacatcggc cgttatcaat
    16801 tagatgcttc atacttaaac ggcgactatt cagctgccaa tcaagaacgt gtagcagaac
    16861 aatatgtaac atctcgttat ggttcatggg atgctgctaa aacattctgg ttagcaaacg
    16921 gctggtacta agccgataaa aggaaaatga tgaaaccgag aaacttgttt attcggctct
    16981 ttgtcaataa ggactgatgg gttgtacaaa atcaaatctg ggtcagaatg aacc
//
LOCUS       DAFELK010000058        17007 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFELK010000058
VERSION     DAFELK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.060"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..126)
                     /locus_tag="LP433_002279"
     CDS             complement(<1..126)
                     /locus_tag="LP433_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBL2006414.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(230..541)
                     /locus_tag="LP433_002280"
     CDS             complement(230..541)
                     /locus_tag="LP433_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2006415.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(543..740)
                     /locus_tag="LP433_002281"
     CDS             complement(543..740)
                     /locus_tag="LP433_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBL2006416.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1134..2861)
                     /locus_tag="LP433_002282"
     CDS             complement(1134..2861)
                     /locus_tag="LP433_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBL2006417.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2854..4047)
                     /locus_tag="LP433_002283"
     CDS             complement(2854..4047)
                     /locus_tag="LP433_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2006418.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4234..4878)
                     /locus_tag="LP433_002284"
     CDS             complement(4234..4878)
                     /locus_tag="LP433_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2006419.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4972..5106)
                     /locus_tag="LP433_002285"
     CDS             complement(4972..5106)
                     /locus_tag="LP433_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBL2006420.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="LP433_002286"
     CDS             complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="LP433_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBL2006421.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7237..7710)
                     /locus_tag="LP433_002287"
     CDS             complement(7237..7710)
                     /locus_tag="LP433_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBL2006422.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8111..8335
                     /gene="nrdH"
                     /locus_tag="LP433_002288"
     CDS             8111..8335
                     /gene="nrdH"
                     /locus_tag="LP433_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBL2006423.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8494..10653
                     /gene="nrdE"
                     /locus_tag="LP433_002289"
     CDS             8494..10653
                     /gene="nrdE"
                     /locus_tag="LP433_002289"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBL2006424.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10703..11668
                     /gene="nrdF"
                     /locus_tag="LP433_002290"
     CDS             10703..11668
                     /gene="nrdF"
                     /locus_tag="LP433_002290"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBL2006425.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11757..12896)
                     /locus_tag="LP433_002291"
     CDS             complement(11757..12896)
                     /locus_tag="LP433_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2006426.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13205..13918)
                     /locus_tag="LP433_002292"
     CDS             complement(13205..13918)
                     /locus_tag="LP433_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBL2006427.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="LP433_002293"
     CDS             complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="LP433_002293"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBL2006428.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15107..16639
                     /locus_tag="LP433_002294"
     CDS             15107..16639
                     /locus_tag="LP433_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2006429.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16830..>17007)
                     /locus_tag="LP433_002295"
     CDS             complement(16830..>17007)
                     /locus_tag="LP433_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2006430.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5324 t
ORIGIN      
        1 tgaaaaaaca cattccacta aatttgatgc cggttttcct tgaggttttg ttccagcacc
       61 tcctttaatt tttttaagct cttgatctga acattgttta gcatttagtc tatttttttc
      121 ttccattacg attcccccta caaactataa atacttttat gtcactgatt caatatacct
      181 atttttctaa tcaaaaaatt ttgagacata tttaatatta taagtatcat taaaattgag
      241 atttatctcc ataatctgct cgatataaac catttattcc agcagttctt ccaatttcac
      301 tcaaatttct tattaattcc tcttgatatt cagtgaatct tattttatta gtataagcag
      361 taaaatatag ataattcacc aatctattta ttaaaggact gggatctaat tcatattttt
      421 gtttttctaa ttttaaatat accttttgta aaacctcaag aatatcagaa tatttaggat
      481 ctttacttat agatatatca ttatataatt catgaacaat ttgcttagca ttttttttca
      541 ttttagcact tccctggaat tgctccacct aaaaaaccac ctatagacat tcctgcaata
      601 caagtagttg ccttggccca atcgaccgta catttatttt tagtgcaata cactccattt
      661 ccataatatt ttccactatg agtggtaccc ccatagataa gttgtgtctc tttaatagac
      721 aaaattttta aatgtttcat aatctaatca cccctaaatt aatgttttta gactattatt
      781 ctaacattca ttaaatttca aaaaacaatt ccttcttgaa acgtagcaaa ataattcctg
      841 aataagaatt taatcacttt taagtatata aactatgtat attctttaat attttttgag
      901 aatgcacttc gtacataata aactttaatc acattagtct ttcataccta cgatcgatct
      961 ctttgactcg cacccataaa ttcataatag tttgtcggcg tctttgaacg tttcgaagat
     1021 gagctacgca ttctcttttt ttatagacaa aaaagataga gacgaacatg gagcttccaa
     1081 atttggatat ttgatccaat tttggaagct ccatttattt cgtgtctgtc tttttatttt
     1141 ttccagcttt cgactaattc ttggttctct ttgatccagt cttttgctgc ttgctgtgga
     1201 tcttttccat tgttgatttc caacataact ttttccatat ctttttctga ccaatggaaa
     1261 ttgtctaata ctttgtaagc ttctggctgg tcttctttca atccttttcg aaccatcgta
     1321 tggatctgct cttcgcttcc cattccgttt tcaggatctt ctaagtattt cagatcatat
     1381 ttggcaaaca tccaatgagg tgtccatcct gtaactacaa ttggttcgtg ttttttgatc
     1441 gcttgaccta gtgcaacggt cattgctcct gaagaagatg tctctacttt ccagtctttc
     1501 aagttgtcat atttttggat cgtgttttca gcagccgtaa ctacaccagc tcctggctcg
     1561 attcctatga ttttcttacc tgcctgatcg gttaactcat cgatcgaatt tacatccatg
     1621 taggctggca ctgctaaacc aacttttgct cctgtcaaat tggcacctag gtcttcgact
     1681 tgatctttat attgtgcata ttgtgaacca tgagttttag gtagccaagc tgaaaccatg
     1741 gcatctgact cgccatttga aacagatttc cacatgattg aattatctaa tggcgtcatc
     1801 gttacatcat agcccatttg tttcaatact tcaccgacta catttgttga agcaacttct
     1861 gtatcccatt caacataaga taagttgata cgttttgttt ctttggcaga tgaaaaactc
     1921 cctataccaa tcgcacctaa gatcactact actacagcac caatgatcag tccttgacgt
     1981 tttttacttt tctgtgttgt tgctcctgca gcttttttat tgtttggctg gttcaaatgc
     2041 tgtgtaaaac ggtcaatgat gattgctaag ataactaatg caaccccgtt gacaaatcca
     2101 ttcccgactt gtgctctttg caatgctgat aatacgccgc gtcctaagcc gggtgcaccg
     2161 atcatagagg caataacgac cattgaaagt gacagcattg ttgtttgatt gatccctgcc
     2221 atgatcgtac ttttagctaa aggcaattct agtttgaata gtttttgacg acttgtgctc
     2281 ccgaatgaat cagaagcttc tactaattct ttaggaactt gtcgaatccc taaattcgta
     2341 aaacgaacgg ttggtggcag agcaaagatg actgaggcaa atacccctgg aaccatcccg
     2401 ataccgaaaa atgcaactgc tggaatcaaa taaacgaatc ctggcattgt ctgcataaag
     2461 tcaaggatcg gtttgataat actttgggct ttactgcttt ttgccatcaa gatccctaat
     2521 ggtaccccaa tgatgatcga gatcacacta gataaaagaa caagtgtgac agtattcatc
     2581 aaatcattcc atagaccttg gttataaata aaccatagac cgattaatgt gaacaacgta
     2641 agtcctggac gtttcttaga aataaagaaa gctgctaccg tcaataacaa gataaacaaa
     2701 ggagctggaa tcactaacag taaatttgta atccccgaca tcactgcctg tccaatcgtt
     2761 tgtaaaaatg aaaataggcc agaaaaagtt gtcgtaaacc attctgtgat attttctacc
     2821 cagtttgcca ctggtaattg atagttcaat agattattca tgttcactca cctcgcttgt
     2881 ttctgctaat gcttcaatca cactacctcg gatgacgaca ccttttaatt ttccatcctc
     2941 tacaactgca agtggagtcg gtgagtcata aataatattg aaaatatcac ttaccaccat
     3001 gtctttccca atcaccgtca cattttcatc taggaagtcg atcaatggac gtttttgctt
     3061 cctagcttct aacgcttgat ctgcagtgat gatccctttc aggtgtctct ttctgtcaac
     3121 agccatcagc atgctgactt cttcattacg catccttgtc aatgcaacgt ttggtccatc
     3181 agattcgata ttcgtcgtca atgcaggtac catgatgttt tgagccgtaa gcactttgga
     3241 acgatcgact tcttccacaa attcacgtac ataatcattt gctggattgg tcaatatttc
     3301 ttcacctgtt ccgatctgca tgatttcgcc gtctttcatc aaggcgattc tgtccccaat
     3361 ccgtaaagct tcattcaaat catgggtaat gaaaataatc gttttttgaa cattggcttg
     3421 caggtccagt aattcgtctt gcatttctcg ccggatcagc ggatcaagag ccgagaacgc
     3481 ttcgtccatc agcaagatct caggatcatt tgctaaagct ctggctaggc caacccgttg
     3541 ttgcatccca ccagataact gactaggata ttggtcttta aatgaaagca aactagaatt
     3601 ttctaatgct ttttctgctt tttcttgtcg ttcttcttta ggtacaccac ggacttctaa
     3661 cccgtattct gtattttcca agatcgttcg atgtggaaac agaccgaagt tttggaaaac
     3721 catattgatt ttatgacgac ggacttctcg caattcttct ttgcttaact tcgatacatc
     3781 ttctccatca atatagatac tgcccgaagt tggctcaatc agacgattca atagacggat
     3841 caatgtggat ttcccactcc cggaaagccc catgatcacg aagatttctc cttcttttac
     3901 gtcaaaattc acgtcataca caccaaccgt tgcaccggtt ttctttaaaa tctccgtttt
     3961 cggctggtga tcattcatca tatctaaagc ggcttgtgtc tttttaccaa atatctttgt
     4021 taaatgtttt acttctactt ttaccaaaca aattctcctt ttttatgtaa attcattttt
     4081 ctttctgaaa aaagtgacca cactatgtta acatcatgta gtcactttgt caaaaatgaa
     4141 agaaatttgc ttgtccaaac tgaaaaaaac ttggctaaat ctttgtaaat aaaaggttta
     4201 gccaagttaa tattttttta atatttcaca caatcattct gcaagctgat gctccgggta
     4261 aaaaaagttt gtcatacgct gtagtgtata ttcatttcca ataaaatgaa cgatgtcccc
     4321 tgccgtaaat ttagcatagg ggccaggtga aacaagcagt tcttcattat gagaaattgc
     4381 gataactgtg gcgccagtcg cctgccagat attcaactcg ctaattgaac ggtccagatg
     4441 cattgctttt tctgataaag ataattcaaa cggaagtaaa ggattcatct tatgtattcg
     4501 cttcgtttga ttgaccagct gatccaataa ttgagaaaaa tgattcagct catcttgttg
     4561 cttctccaca cttgccatga tttctgcttt tgtatcttgg atggattgta catcttgata
     4621 ttgcaatagg aaatcttttg ctttttcctt cgaagcaaca aatgccccac ttccatgccg
     4681 tacttccatg attccaagat ctaccagcac attgatagcc ttgcgggtag tctcaggaga
     4741 agcattgtac gtactggcaa gtgttgagcg ggcatggatc ttctcaccca ctttatatcg
     4801 gttttcaacg atacgttcgg ctaaatcaac agcaatctgc tggtagcgcg ggcggacgat
     4861 ttttttcttt ccagacattt tctttcctct ttcttttttt actttccctc atcttactat
     4921 gctctagcaa aataagcaaa aaaggggaga atagcctctt gcaacgactg atcatcgctt
     4981 gatctgttcc ttttttactg ggcaagctgt ttgacagtca tcacaattct taccggattt
     5041 taaacgagta tagacaattg cgcctgcact tccaaagatt aacacactta ataagaatgt
     5101 cgccatccta ttcctctcct tctaatgaca atatagtata aaactggttc ttggattttg
     5161 gctgacggaa caaaacataa acgagtccta tcatcagtaa aatagcaaga tacgtcccta
     5221 acgctacctg tccaccctcc aataagtgtc ccaactgata aatcacaaaa ctaactaaat
     5281 aagctaaacc gcattgatag cctatggcga tccaagtcca tttcttggca ttcatttccc
     5341 gatggatagc cccaattgcc gcaaaacaag gcgcacaaag taaattgaag gctaacaatg
     5401 aataagctgc tgcgggagta tatgtgtgtt gtagcacttg ccagatttct ctgccatttt
     5461 cggatacttc cgcatgacca aacaaaatac caaatgtgcc aataatattt tctttagcga
     5521 ccaatcctgt aatcgctgcg actgttcctt gccagtttcc ccaaccaagc ggctgaaaaa
     5581 caactgccag gattcgcccg aaaaaggcta agatactttg gtcttcagaa acaggttgag
     5641 cataaaaatt ataagaagag ctgaaccaga tcacgatact agaaacaaag ataatcgttc
     5701 ctgctttttt aacaaaagac ttgctgcggt cataggtttg tcttaggacc gctgaccatt
     5761 gaggaaaatg atatgcgggc aattccatga taaaaggagc tgtatctcca gcaaacaaac
     5821 gtgttttttt caagctgatt ccagagaaaa taattgcagt cataccaaga aaataggcag
     5881 aaggagctac ccaagattga tgaggaaaaa aggcccctgc tactaaggca ataatcggca
     5941 actttgcaga acaaggcatg aaggttgtga ccatgatcgt caaacgacga tcttgctcgt
     6001 tttcaatcgt gcgactggcc atgacgcctg gcactccaca tcctgtagca atcagcatag
     6061 gaatgaagga ttttcctgaa agaccgaatt tcctgaaaag tcgatccatg acaaaagcga
     6121 tcctcgccat atatccgcag tcttccagaa agctcaagca taaaaacaat ataatcaatt
     6181 gcggtagaaa tcctaacact gctcccacgc ctgcgatgat gccgttcaag atcagctcct
     6241 gcatccatcc cgctacttgc cattcagcta acaatctgcc aacatgttct ggtaaccatg
     6301 taccaaacaa tgtgtcattg atccaatctg tccccattgt tcctactgtt tgaatagcca
     6361 gataatagat cagccacatc acaaatgcga agatcggcaa ggctaaccaa cgattcgttg
     6421 caatctgatc gattttgtca ctcatcgata attggaaaga atcatttgac acaacacaga
     6481 gtgtacatag ttgggtaata aattcataac gttcattgac cagaatcgtc tcactatcgt
     6541 cgtccaatag tttctctgtt aactggatca gttgctcgat ctctttttgc tgagaaactg
     6601 ctatctcgta atcctctctt accttctgat ctcgttcaaa atatttcatt gcataccagc
     6661 gtttcttgcc gctttgttct cctagtacat cttcaatttc atgtaaagct gcttctaaac
     6721 gtggatcata tgtacaggga acaggaatag aaggccgctt ttttgcagac tcctgaatct
     6781 tttcgattag tttttcgatt ccttgctttt tcaatacgct gattggtaaa actggtacac
     6841 caagaccata ggaaagcttt tctagattga ttttttttcc ttcttttttg atgacatcca
     6901 tcatattcag accaatgatc ataggaatgt ctaaatccaa taactgcgta gttaaataaa
     6961 gatttcgttc taaattggta gcatcaataa tgttgatgat cagttcaggc tgttcctgaa
     7021 ccaaataatc tcttgcaatc acttcttctg gtgtataagg agacaaagaa tagatgccgg
     7081 gtaggtcctg aatatgaatg ttcggatttt ttttcaacga tccttctttt ttttctactg
     7141 ttacgcccgg ccaattccct acatattgat tcgaaccagt caagagattg aacaagctag
     7201 ttttcccgct gtttggattt ccgactaacg cgatattcat tctttttcct ccctttgtat
     7261 caagattagt tcggcctctg actttcgtaa cgtcagttca taccctcgca ctgtcagttc
     7321 gattggatct cccagagggg ctagttttcg gataactatt tttacatttc gcgtcaatcc
     7381 catatccatt aaccgtcgct tcactgcgcc ttgtccgtgg attgctacga cgatcccagt
     7441 ctctcctgct tttaattgat caagagaagt ccagctttca gaggaagcag tctttttatt
     7501 gacaaagatt tgacctagta tttcccgact tactgccact cgatgacttt ttaccagtaa
     7561 aatggcattg ttgcctgata aattgacgac gacgatttta cttccggcaa cgatcccgat
     7621 attttgcaaa tggcgttttg ttttttcttc tgtttcgatt cgttcgactt gataaacgaa
     7681 attctgcttt gcctgcgcta aggtctgcat attgattcct ctcttgtgaa ataaatcatg
     7741 tattaaaatc attcattata tgttctaatt ttcttacgtg ttacgcaaat aaatgagaat
     7801 cattctcaca tagaatactc tcggtaattg agaatgtcaa ttatacttgt gatattatga
     7861 gcgaatcttt agtattgata gataaaaatg agaaaaaaat atttcttcat agttttccac
     7921 aattttttct ctattaaatt tgctattttc ccacacgata cttgttttca gctctttttt
     7981 caaaaacaca aaacttagta ttccacagtt tccacaacac aatatgtagt gtttgttgtt
     8041 tgactttttt actaagagtt ttatactatc tattatagat aataagaatg tgttagagga
     8101 ggcactcacc atgaacgtaa aaatcttttc taaaaataat tgtatgcaat gtaagatggt
     8161 caaacggttt ttaacagaaa atcaaattgc ttttgaagaa gtcaatatcg atgaacagcc
     8221 tgaagcagta gactggttga aagcacaagg attccaaagt gttcctgtca ttacttctga
     8281 tgcagaaaca gttatcggat tccgtcctga tcagttgcgt aaacttgcca gctaacatga
     8341 ctaaaagaat caaaacgtga tacatggatt tgaagggctt gagacagcac cagtttttgt
     8401 cgcaaacttc caaatccttt tttaaagctt aaaaacaatg caatgatttg caatcaagca
     8461 tcatcaaata cgaaatgaag gttgggcgta cgtatgagtc ttaaaaattt acaagatgtc
     8521 agttatttca agctgaataa tgaaatcaat cggccagtca atggtcaaat ccctttgaat
     8581 aaggataaag aagctttagt tgcctttttt gaggaaaatg tcaaaccaaa tacgatgact
     8641 tttccatcta ttatggaaaa aatcaattac ttgatcgatc aagaatatat agaagcagaa
     8701 ttcattcaat tgtattcacc atcatttatt gaaaagctat atcaattttt ggacgagcaa
     8761 catttttctt tcaaatcttt tatggctgct tacaaatttt attctcaata tgcgttgaaa
     8821 accaacgacg gttccgctta tctggaaact tatgaagatc gagtagcctt caatgcgctt
     8881 tactttgcga acggggatga agaattagca cttgctcttg cagacgaaat gatccatcaa
     8941 cgatatcagc cagctacacc ttctttcttg aatgctggac gtaaacgtcg gggcgaattg
     9001 gtgtcttgtt tcttgactca agtcactgac gatatgaact ctatcgggcg ctcaatcaac
     9061 tctgctttgc aattgtcccg tattggtggc ggcgtaggga ttactttatc aaatcttcgt
     9121 gaagccggcg ctcctatcaa aggatatgag ggtgctgcaa gtggtgtcgt tccagtcatg
     9181 aaattattcg aagatagttt cagctattct aatcaattag gtcagcgtca aggagctggc
     9241 gtggtttatt tgaacgtttt ccatccagac attattgctt tcctttcagc aaaaaaagaa
     9301 aatgcagatg aaaagattcg cgtaaaaact ctttctcttg gcgtgatcgt acctgataaa
     9361 ttttatgaat tgacacgtaa aaacgaagat atgtatttat ttagtccata tagtgtcgaa
     9421 aaagaatatg gtgtcccatt ctcttatgta aatattacag ctgagtatga tcatctagtt
     9481 gcaaatccaa acattcgcaa acaaaaaatc aaagcgcgtg atcttgaaaa tgaaatctca
     9541 aaattacaac aagaatctgg ctatccttac gtaatcaata ttgatacagc gaaccgcgag
     9601 aatccaatcg atggcaagat catcatgagt aatttatgtt cagagatttt acaagttcaa
     9661 acgccttctg tgattaacgg caaacaggaa tatgaagtat taggaacaga tatctcatgt
     9721 aacttaggct cgacaaatat cgtgaatttg atgcaaagcc ctaactttgg tcaatctgtg
     9781 cgtacgatga ctcgtgcatt gacatttatt acagatgcat ctgatatcga tgtcgtacca
     9841 ccgatccaaa acggaaataa gctgaatcat acgattggat taggtgccat gggcttacac
     9901 acttatcttg caaaagaaca aatggaatat ggctcagagg attcattaga ctttacaaat
     9961 atttacttca tgctgttgaa ttattggaca cttgttgaaa gcaacaatat cgctcgtgaa
    10021 agaaaacaag ttttccataa ttttgaaaaa tcagcttatg ctgacggcac ttatttcgaa
    10081 aaatacgtaa ctggagaatt ccagccaaaa tcagaaaaag tcaaagcatt gtttgaaggc
    10141 atttttatcc caactgctga agattggaat gctttgaaac aagcagtaat gaaagatgga
    10201 ctgtatcatc aaaatcgctt ggcagtagca ccaaatggct caatttcata tatcaacgat
    10261 acgagtgcaa gtattcatcc tatcactcgc atgatcgaag aacgccaaga gaagaaaatc
    10321 ggtaaaattt attacccagc gccttatcta tccaatgaga cgattccgta ttacacttct
    10381 gcttatgata tggacatgcg taaagtaatc gatgtttatg caacggcaca acaacacgtc
    10441 gatcaaggca tgagtttgac tttattcatg cgttctgaaa tcccagaagg catttatgaa
    10501 tggaagacaa caacgaagca aacgacacgt gatttgaata ttttaagaca ttacgctttc
    10561 cacaaaggaa tcaaatccat ttattacgta cgtaccttta ctgatgatgc agaagaaatc
    10621 ggaagcaatc aatgtgaaag ctgcgtgatc taatatcata gatagattcg cttattcata
    10681 ttttaattaa aggagcattc tcatgtcaga aacatattat gaagcaataa actggaatga
    10741 aattgaagat atcattgata aatccacttg ggagaagctg acagagcaat tttggctaga
    10801 tacacgtatc ccactttcaa atgacctaga tgattggcgt acattgtctc aattggaaaa
    10861 agatacagta ggacatgtat ttggcggttt gacactgcta gatactgtcc aatctgaaag
    10921 tggcatggat cagttgcgta aagatgtccg cactccccat gaagaagccg ttttgaacaa
    10981 tattcaattc atggaatccg ttcatgccaa aagttattct tctattttta gtacactgaa
    11041 tacgaaaaaa gaaatcgaag aaatttttga ctggacaaat acgaatcctt atctgcaaaa
    11101 aaaagctgag cgtatcaatg aaatctacaa acacggtaca ccgctagaaa agaaaattgc
    11161 cagcgtcttt ttagaaacat tcttgttcta ttcaggtttt tatactcctc tttattattt
    11221 aggaaacaac aaattggcta acgtagcaga gatcatcaaa ctaatcatcc gagatgaatc
    11281 tgtacatgga acctacatcg gttacaaatt ccaattagga ttcaacgagt tacctgaagc
    11341 agaacaagaa acgttaaaag actggatgta caatcttctt tatgagcttt acgaaaacga
    11401 agaacgttat acagaagaat tatacgatcc aatcggctgg acagaagaag tcaagacatt
    11461 cctacgctat aatgccaaca aagcattgat gaacctaggg atggatccac tctttccaga
    11521 tactgccaat gatgtcaacc caatcgtaat gaacgggatt tcaacaggca caagcaacca
    11581 tgacttcttc tcacaagtcg gaaacggcta tttgttaggt catgtagaag cgatgaaaga
    11641 cgacgattat ttgattggat tggaataagg atttatttta attcaaaaat ttttcgaaaa
    11701 ataaaaagag tttagcgtac agatatttta aatgtacact gaactctttt ttatgcttat
    11761 tcacttgttt cttccagcac ttttggactg tctaactttt ccgaaacatg ttccattctt
    11821 ctcaataaat agattttccg gatatttaat attatcgtct taatcactgc atagacaggt
    11881 atgcaaatca gcatgcctaa tattcctgcg acacttcctg ctccaatcaa taccaagatg
    11941 atcgtcaaag gatggatatt cattgatttc ccaaataaca acggcttgat caaatttcca
    12001 tctaattgtt ggatcactaa aatcgacaac gccatataca aagcttgaaa tggagagata
    12061 aacaaaccga caatgattgc tggtaccgct ccaataaaag ggccgacata cgggataata
    12121 ttcgtgattc cgcaaatgac cgcaagcaac aagctataag gctgatcgaa tattctcatt
    12181 gccaaaaagc tcattacacc aataatcaaa gcatctaaga tcgtactgct gatataggca
    12241 gataatgttt cgtttaattc ttttaccgtt tggcgtaact ctttacgaat cgctttcgga
    12301 aagaagtgag acaacgcatc aataaatttg tgcccatcct tgaacataaa tagcaaaata
    12361 aatggaacgg taaataacaa aataaaaaat tgcatcataa atgaaatgat ttttgagaca
    12421 cttgcagata aactgactaa tatgatattg aacaaattac taagagataa atttgctgat
    12481 gctaattgtt cttccaaatt gaaattttta aactcttccc gctgcgccaa ttcatttaac
    12541 catttgcttg tttcatctgc atacattggc aagctctggg tcaattgaat tgtctgttcc
    12601 attaactgag gcactacatt catgacagtt aaaacaacta aaatgattac gaccaaaaac
    12661 gtcaataaaa aaccgaacac tctcgggatc cgatgctttt cgagaaaaac aacgattgga
    12721 tcgaacatat aatagataaa accagcaaca agcaatggta aaaaaattgc cgaaagcatt
    12781 ttcaatattg gactaaaaat attcggcatt tgtaaaataa agtacacgcc gatgatcgtg
    12841 agtactagct ccactgtcca gaaaaataat tttgattgtt taaaacgtga ttgcatacat
    12901 ctcctccaag gtcctttgat acttctattc tatcatttaa caaagagtta cgcgctgaga
    12961 ttttcatttg cttaaaaaaa acaaaaaaaa taaacatatt ttaatgagta gacgagtact
    13021 taaacaaaaa cacggtttgg agtagtgaca aaaattatac tgcagtccct ttttccaaat
    13081 aaacggtgtt caaaagcttg catcttcgta ataagcccag ccaaacgaaa aatataagga
    13141 actattttta tttggctggg cttattactt gatgtaggac atctatttta caacctcaga
    13201 tcatttattg cgcaatactg actaaatgca actttgtgat atttttgtgt acggacaact
    13261 cctcgatcac atcggcataa gtgagccctt ttggaagatc aatcgtatag atatttttgt
    13321 acactcggta gtcatcaacg aattttacgt caaaattcac atcttcgatt acgatatttt
    13381 tctcttcaaa ataatcggta agaaaatctt tggtttcttt tctatggata aattggattt
    13441 ctaacttttt agtcgtaggt acatggatca cgcgtttcac tactgtgagt gcaatagcaa
    13501 tcccgataaa actgatgatc gcaatggaat agtaacccat gccgatggcg atccctaatc
    13561 cagcaattgc ccataaagaa gcggcagtcg taagtcccgt caccgattgt ttcgtgacga
    13621 tgatcgttcc cgcgcctaag aaaccgacac cactcaccac ttgagcaatc agccttgctt
    13681 catctgaacg aatcgttcca gcaagctgtg gatactctaa agcatctctt aatgcaccac
    13741 tagcgatctc aacttggatc aatgcaatga tacatgctcc catacaaact aaaatatgcg
    13801 tacgcatacc tgctggacga tttttatatt gtcgttcaaa accgattgct ccgccaaata
    13861 gcatagcgat ccctaaacgt aaaataatct ctggaattgt caataccata tcattcatct
    13921 aaacaccctc cagtccaata tatcatgtct gaaaggagca gacaaaaaaa gtgcaatttt
    13981 tacctcttac gaaaaaagga ctgtgacaaa atttttgtca tagtcctttt tatgaataaa
    14041 cggtgttcaa tcagctgacc ctcggtatta ctcaacaaac ggcaaaatat ggggagctat
    14101 ttttcctttg tcttctctaa tactcaggtc aaaacgctga tttcacaacc tctttagcct
    14161 actattgaaa attacaactt acttgctgct tcttcatcga tgatcacaac aacattgtcg
    14221 tgattttgca atacacttgc tggcaaatga ttcgttacag gtccttcaat catccctttg
    14281 attgcatcag ctttgctttc gccaaatgcc atcaagacga tttctttact tttcataatt
    14341 gaaccgattc ccattgaaac agcttttgtt ggtacatctt ctgctttatc gaagaatcgt
    14401 ttgtttgcat tgattgttga ttctgttaag tcaactactg aagtcgttcc gtcaaatgaa
    14461 gcaccaggtt cattgaaacc gatatgtcca ttttgcccga ttcctaagat ttggatatcg
    14521 attggatgtg catcgatgat ttgatcatac tttttgcatg ctgcttccag atcttctgct
    14581 tttccatctg gtacaaacgt ttctttgaat ggttttttat caaataattg gacatccatg
    14641 aaatgacggt agctttgttc atctgaaccg cctagtccaa cgtactcatc taagtttaca
    14701 gaagtcattt cactgaaatc caaatcgctt gaagtcattt ctttatataa agtaactggt
    14761 gtgcttcctg ttgccaatcc taatactttt gcacctttgt tcataccttc tttgatgatt
    14821 tcaaatgctt tttttccgcc ttcttcagcg ttttttacac gaatgatttc catagtgatt
    14881 gctcctttat attttggtat agcccaatta tagcattctt tttttctttt tacaataatt
    14941 agtatagacc aaattgcatt tttttcattt tcttgacaat aaataggaat ccgtgttagg
    15001 tttcataaga tggttcaatc aaacaatcca tgttgcatga aaaccaagca agtgattcac
    15061 tgtggacgct ttatgtctgc agttttttta tgaaaaagga gttattatga gtatactgac
    15121 attaaacaac attacccagc aatttggcga caaaatcctc tatgaaggtg tcgatctgca
    15181 attaaatgct ggcgaacatc ttgggctgat tggacaaaac ggagccggta aaagtacatt
    15241 gattaaaatc atcactggtg agatcttacc agatgacgga cagatccatt ggcaaaaaaa
    15301 tattcacaaa ggttacctcg atcaatatgt ggaagtcgat gaaacattaa caatcgaaga
    15361 atttctaaaa actgcgtacg caaaagaata cgaaaaggaa gaaaaaattg cttttcttta
    15421 ccaaacatat agcgagacct tcgatgattc cttgctggaa aaagctggga aactccaaac
    15481 ggaattagac caaggagtgt tttatcaaat cgacacctta gttgctgaga tgagcagcgg
    15541 gttggggatc gatgtcttag gtttagattc actgttgaaa aatctaagtg gtggacaacg
    15601 ttcaaaggtg attttagcaa aactactttt agaaaaccca gatgttctga tcttagatga
    15661 accaaccaat cacttagatg atcagcatat ccaatggctg acgcagtttc ttcaggattt
    15721 tgacggtgcg tatatcgtga tttcccatga ccaagaattt cttgatcaga tcaccaccca
    15781 tatcgcagac atcgagtttg gaaagattac taagtatact ggccatctaa aacaagcatt
    15841 gaaacaaaag gaacaaaatc gcgaaagcta tttgcgccaa tatcatgctc aacaaaaaca
    15901 aatcgaaaag accgaagctt atattcgaaa atacaaagcc ggttcccgat caacgatggc
    15961 aaaaagccga caaaaacaat tagataaaat cgaacggctg acgcctccag cttcagcaag
    16021 taaagctgtc tttgattttc cattctcgcc tattgtcacg acattagcag tggaaacaac
    16081 tgatttagtc atcggatatg atcgaccgct acttgcaccc atcaatttga ccatccgctt
    16141 tggtgaaaat attgccattc gaggcttcaa cgggattgga aaatctactt tattaaaaac
    16201 actgatcggt gagattgaaa aaataagtgg cgatttccac ttcccagata acacaaaaat
    16261 caattacttt tcacaagatc tgtactggga aaatccatta gaaacaccac tacaatattt
    16321 aagcagtcaa tttccaaaag cgactatcaa agaattacgt cgccaactag ctaaagcagg
    16381 gttagttaat caattagcaa gtgaacctct cactacatta agtggtgggg aacaaactaa
    16441 ggtgaaactt gcacagttga caatgaacca aggtaattta ctgattctcg atgaaccgac
    16501 gaaccatatc gatcaagaaa cgaaagaaag cttacaagac gggatacaga aatttccagg
    16561 aacagtaatc atcgtctctc atgaacaaga attttatcaa gatcttgtgc aacgagtcat
    16621 tgagattgaa ccaaaataaa cgtttgattg aatagttgaa aaaaaggagc tgtgacaaaa
    16681 gttttgtcac aactccttct tctgaataaa tggtggccaa ttagctgacc ttcggtatta
    16741 gctcaaaaaa cggcaaaata tgaggagcta tttttatttg gctattctta ttacttgatg
    16801 cagaacagct tttcacaacc tcttttcgtc tattttttat tttcgagatt tctctttcct
    16861 ttaaaaacaa ctgtttgaaa gaagaacgca catccttgaa aaacaagccc gctaaccgtt
    16921 acacctaacc agccatactg ctgccacatt gtcgtcccta gcaatgaacc agccgcacct
    16981 ccaataaagt acataaacat aaataca
//
LOCUS       DAFELK010000059        16881 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFELK010000059
VERSION     DAFELK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.061"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(258..1763)
                     /locus_tag="LP433_002296"
     CDS             complement(258..1763)
                     /locus_tag="LP433_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2006431.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1760..2446)
                     /locus_tag="LP433_002297"
     CDS             complement(1760..2446)
                     /locus_tag="LP433_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2006432.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2639..4060)
                     /gene="gndA"
                     /locus_tag="LP433_002298"
     CDS             complement(2639..4060)
                     /gene="gndA"
                     /locus_tag="LP433_002298"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBL2006433.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            complement(4230..4409)
                     /gene="rpmF"
                     /locus_tag="LP433_002299"
     CDS             complement(4230..4409)
                     /gene="rpmF"
                     /locus_tag="LP433_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL2006434.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(4467..5036)
                     /locus_tag="LP433_002300"
     CDS             complement(4467..5036)
                     /locus_tag="LP433_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBL2006435.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            5222..6124
                     /locus_tag="LP433_002301"
     CDS             5222..6124
                     /locus_tag="LP433_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2006436.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(6159..7943)
                     /gene="pyk"
                     /locus_tag="LP433_002302"
     CDS             complement(6159..7943)
                     /gene="pyk"
                     /locus_tag="LP433_002302"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBL2006437.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(8017..8979)
                     /gene="pfkA"
                     /locus_tag="LP433_002303"
     CDS             complement(8017..8979)
                     /gene="pfkA"
                     /locus_tag="LP433_002303"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBL2006438.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(9147..12461)
                     /gene="dnaE"
                     /locus_tag="LP433_002304"
     CDS             complement(9147..12461)
                     /gene="dnaE"
                     /locus_tag="LP433_002304"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBL2006439.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            12692..12877
                     /locus_tag="LP433_002305"
     CDS             12692..12877
                     /locus_tag="LP433_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBL2006440.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(12939..14135)
                     /locus_tag="LP433_002306"
     CDS             complement(12939..14135)
                     /locus_tag="LP433_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL2006441.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(14305..15741)
                     /locus_tag="LP433_002307"
     CDS             complement(14305..15741)
                     /locus_tag="LP433_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL2006442.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            16034..16843
                     /locus_tag="LP433_002308"
     CDS             16034..16843
                     /locus_tag="LP433_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2006443.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         4955 a         3539 c         2949 g         5438 t
ORIGIN      
        1 aaataataat atagcaatct ctttataaaa ttgcaataga aaattcccta tttttattta
       61 ttatttttaa acacgaatat tacagcattt tattgttttt tcgttcatct aaaagatact
      121 tacatttaat taacggatgt tattctattt aattgttcgc tagttttttt ataatgacat
      181 ccctgaattt ctcacttgct tgtattttgt accttattct ttgttggata tataaaaaaa
      241 caagtaaagc acatgcttta cttgtcttct gcctttgcga taggaataaa gattctaaaa
      301 attgtccctt gccctactac actttctgct aagatacgtc ctttatagtt ttcaaccagt
      361 tgtttagcga tagacaaccc cagaccattt ccacccttcg ttctagctct tgctttatcc
      421 actcgataaa aacgattgaa gatcttatta aggtcttctt tgggtattcc ttcgccaaag
      481 tcctgaatcg cgatctcaaa ttcattcaga gtggaagaaa tagagatatg gacttctttt
      541 cgtgtagttg aatactttac tgcgttatcc aatatgataa tgattaattg ttcaaagtga
      601 ttacgataaa tttgcagggt cacttctttt gtcaaatcat catctaaagt gatcacatag
      661 tctggatata atatcttgaa attattataa acttgatagg tgacttcttt tcctttagtt
      721 gtttcattcg cataatgaac atctacttgt tctgctcttg ataagtctag catctcttga
      781 actaagcttt tcatacggct gatttcttgc atgctggcgc ttaatgattc ttctaatatc
      841 tcaggatcat ctttccccca acgatttagc agactaagat gcccttcaat aattgcaaca
      901 ggtgtcctta actcatgaga tacgtcttcc acgaattgct cttgttgttc aatatacaaa
      961 cgcatacggt caagcatctc attgaatatt tcagctaaat ctgccaattc atcatttgtg
     1021 tcgatttcag gcatgtggat atctgattgc ggatctttac gtatagtatc cattgtatct
     1081 ctgagtacct tgagtggttt taagaaataa gaagataaaa agaaacctaa aatactactt
     1141 aagatcaaag aaacaacttc taaaacaata agagtcaata atagcttatt tcgaatatca
     1201 tagaaagaag ataattcata gaagctttgc gcatagccga tcttttctct tgtaccttta
     1261 gaatatatag gctggataga taaaaagcca gtttttcctt ctagtgtaac gatcgttgga
     1321 actttacgtg tagtctgaat caggtttcga ctgttttcat gggttttaaa aatcaagttc
     1381 tcgtccaaat cataaacata aagatccatt gatggctgcc ctagctcagc tataaaggaa
     1441 tcgatcttca ttaagtttcc ttcgaccagt gaagtatgat ctacgacctc atctccgtca
     1501 tttgtcgctt tcgtcagatt acgatacgta tttactaatg tcagttcttc atccgagtta
     1561 gccaaacgag aagctacttc tgaaatcgta cgctctacat tgtttctttc ttttgccaca
     1621 atcagattga tagatgattt ataggtaatg acagcgaaaa ttgtaaacac aacgaatatg
     1681 aagaaagaac tcgcaaaggc ccacttgatt gtcaaggagg gccctttcag ttctcttttt
     1741 tccgattttt tcggctttat cacgagcgca tcacataacc tgttccgcgt acagtttgga
     1801 tatagctttc ctccccggga acgtcaattt tgttgcgaag ataacgaata tatacgtcca
     1861 ctacgtttgt ttcaacttct gtttcgtatc cccacacttt atttagtaaa acgtcacgtg
     1921 ctaataccac gttcacgttt tccattaaag taagcagcaa ctcgtattct ctttttgtta
     1981 gttcaattac ttcatttccg cgacgtacga cacggttttc tttttcgata gtcaaatcgc
     2041 gataagtaat agtagtttgt ttagccacat ttttatcgcc ttcaatatcg attcgacgca
     2101 acaatgcacg aagacgtgct aataattctt cgatagcaaa tggtttgacg atgtagtcat
     2161 ctgctccgtg gtcaagtcca gatacacgat cgatcacaga atctcttgca gtcatcataa
     2221 tgattggtgt atttttgact tggcgtacac gtctgcagac ttctaaaccg ttcaattctg
     2281 ggagcatcag atccaacaat atggcatccc actcattatt taatgccgca tctaaaccag
     2341 ttcggccgtt gtagtggact tctgcgttat acccttcatg cttcaactct agctcgacaa
     2401 atcgtgccaa gttcttttca tcttcaatga ttagaatatt gctcatttat tattttatcc
     2461 tttctattct actggctttt taaaaactct atcattatac cgataatatg cttaaaaatc
     2521 tatagtcatt ttattatgga tagcaatttt aaaaaagagc tgaagtctac tcataacaat
     2581 cgacttcagc tctttcgtcc tctttttatt ttctcatttc ctaacagccg aaagactatt
     2641 attcttcatg gtaccatgag taatggaaga ttccttcttt gtcgacacgc tcataggtat
     2701 gtgcgccaaa gtaatcgcgt tgggcttgga ttatatttgc aggcagacgt tctgctctgt
     2761 atgaatcgaa gtaagcgatg gctgatgaga aagtcggtac aggtacgcca gcttggacag
     2821 ccaaggcaac gacgtctctg actgattgct gatatttttt cgtgatttca acgaagtaat
     2881 catctagcaa taaattttcg atctcaggat ttttgtcata ggcatccgta attttttgca
     2941 agaatcgagc tcggatgata catccagcgc gccagatttt tgcgatttca ccaaatggca
     3001 agtcccaatc aaattctttt gaagcgacac gtaattgagc aaatccttgg gcataactca
     3061 tgattttact gaaatacaac gcttctcgga ttttttcgac caattctttt ttgtctcccg
     3121 tgaactcaaa atcgttcgta cgagacaaaa tcttgcttgc ttgtacgcgt tcttctttat
     3181 aagcagaaat atagcgggca aatacagatt cagtgatcaa tggaagtggc acacctaagt
     3241 caagcgcgct ttggcttgtc catttacctg ttcctttatt cccagctgca tcaaggatca
     3301 catctactac tggtttacct gttccttcat cgtctttacg tgtcagaatg tcagcagtga
     3361 tttctatcaa atagctgtct aattcgcctt gattccattc tttaaagata tcagccattt
     3421 cttctactga aaggtttaaa atattcttca ttaagtcata agattcagca atcagttgca
     3481 tatctccata ctcaataccg ttgtgtacca ttttcacata atgtccggct ccatttgggc
     3541 caatatatgt gacacatggt gctccgtctt ctgcttttgc agaaatttgc tctaagattg
     3601 gtgcaactag cgcataggct tctttttgtc caccaggcat gattgaaggt ccttttaaag
     3661 ctccttcttc accaccggaa acgcctgtac cgataaagtt gatgccagag ttggctaact
     3721 cttcattacg acgcatcgta tctttaaaga atgtatttcc tccgtcaatc aaaatatcgc
     3781 ctttatcaag gtgaggaagt aactcttgga ttgttgcatc tgttgccggt cctgctttga
     3841 ccattagcaa gatccgacgt ggtttctcga tagattctac aaattcttcg attgtatatg
     3901 ttgctttgaa atttttatct gggtgttctt ctactacagc ggttgtttta gcccctgtac
     3961 gattgaataa agccactgaa tagccgcggc tttctatgtt caaggctaga tttttaccca
     4021 taacggccat accgacaacg ccgatttgtt gttttgacat atgaactcct cctacatacg
     4081 ggatttctcc ctaatctctt acattatagc ttaacacggc tacattgcaa actaaagaac
     4141 aacatatttt ttatttaccg actacaaaaa aataaacctc aaggctccat ggttagcctt
     4201 gaggttttac attttctaat taaaatgtat taagcttctt ttgacattac gtccttacca
     4261 tcatagtaac cacaatttgc acatacgtga tggctttttt tcatttcacc acagtttgga
     4321 cattcgttta accctttgat tgtcaatttg tagtgtgtac gacgttttgc ttttttagct
     4381 tttgatgttc ttctagctgg tactgccatt ttgctacacc tccttgtaaa gtcttgtatc
     4441 taaattagac acaatatatt ccaatcttac ttgttatcgt cgtcttttga tttagaatca
     4501 aaaagttcag atagttttgc aagacgagga tcaattttat tctcggcttc ttccattttt
     4561 ctgcgctggt attcttcttc ggaaacaact tcccaatcat tgccttttgg aagttctgtt
     4621 gctgcttcct cttcttttgt caatacccgc attggaatcg ccaataagat gttgtcttca
     4681 atcgactctg ctaaattcaa taatggacct tcaattagca aaatctcatc tgcagacatt
     4741 tgttcatctc tactttggaa ttgttcttct gtcatgaata cttcgtctac agaaaaatcc
     4801 atgggcagtt caacaggttc tagtgaacgt gttgaaggaa ctgtcaaagt cgtctgcaca
     4861 gtgtaatgaa cgatatagcc tttcttatca actgagacca aaccttcgac ttccactggc
     4921 gcaacatcaa gtattaaatt gtctcgcttc atgagagcgg ctttcaagtc gagcgtctca
     4981 tgaaaagtta acggtgtctc ctggtatttt ctcaattcca ataaagacca tttcattttt
     5041 catcactcct aagcaacaaa agcaattata cagggcaaaa agcatgttgt caatgaaatt
     5101 ttcttgacac cttgcagttc ataaaaaaac agaaaaatct ttattagaaa gcctctgttt
     5161 gctatcatcc tcagaatcat ttacaataat cattattcca ttaaaggagc ggatgatctt
     5221 catgaacacg aaagatatcg aatactatgt ccaaatcgtc aaacaaaaaa attttacgaa
     5281 agtggctaat tatttccgtg tgagccaacc tactattaca tatgcattac aacgtcttga
     5341 aaaagagttt gacaccgtac ttattacaag agatcgatcg catcacgaat tgatcgtcac
     5401 gccttctgga aagcagctgt ttctccatgc acaaaccatt ctccaagaga tttctactgc
     5461 aagagctgaa atcactcagt tgcaaaagaa aaagcttcgt tttggcatgc ctcctattat
     5521 cggcaatgaa tactttccta aactgtcaag ttactttatc aagcatgaat tgatgaatca
     5581 aattgagatt accgatggag gctctcggga cttatacggg atgatccgac aagggaggat
     5641 cgatttagct gtattaggct caacacagcc aatcgtggat caatatttag aaacagagtt
     5701 acttttggac aaacgtttca tgatcgtcgt gccacctaca catcctcttt ccaagcagga
     5761 tactgtctct ttcaaagata tagcagatga acagtttgta ctattgaacg aacattatgt
     5821 ccaccccgca gcattcacta agctttctaa acaaacacat actcatccaa aagttgttta
     5881 tcaaagcaat gacttgacga ttttaaagag tatggtccga gaaaatgtgg gtatcggttt
     5941 tttggcagag attgctgtcc atcctgaaga tcatttagtt tgcctccctc tttcagatga
     6001 agttcagcct cgcttcttga tttcattggc aaaacgaaca cagcagatcg tcacgcctct
     6061 tcaagaacaa gtagtccaag ttatccatga attcgttaca gcacaaaaaa acagctcttc
     6121 gtaaaagaag agctgttttt attttttatt aagctaaatt agatagctgt tgtttcgcca
     6181 cggtaaacga tgccgcgacg tgaatcaacg gtaatcaatt caccttctgt aattgttgtt
     6241 gttgcgcctt tagcaccaac gattacagga atatcttgtg caattcctac aactgcagcg
     6301 tgagaagtca atccgccttc ttcaacgata acagcagctg ctttttcgat tgcaggcata
     6361 tattctttgt cagttgatgg tacaactaga accattccgt cttttgcttt ttttacagct
     6421 tcttcagcag atgaagcaat aactgcattt gcaacgacag atttttgtcc aacgccttga
     6481 gcttctaata atttagaacc aatcatttga attttcatca cgttagttgt tccgcgttca
     6541 ccaactggta caccagcagt gatcaagatt aaatcgcctt ctgatgcgaa acctaattca
     6601 acagcttttt tagctgctag ttcaaacatt tcatcagttg ttgatggttt ttcagcaact
     6661 gttgggtaaa cgccccagtt taacatcaaa ccacgttttg tgcgttcgtc aaaagtaaca
     6721 gccaagatat ctgcatctgg acgatatttt gaaatcattt ttgcagtgta tcctgattca
     6781 gttgcagcaa cgattgtttt cacgcctaga ttttttgcag cacgagctac agataaaccg
     6841 attgtttcag ttacatctgt tttatcgaat tcgttcaatt ggaatgtacc taattctgat
     6901 aatgcatttt cagcttcttg gtcgatacgt gccattgttg aaacagcttc aactgggtag
     6961 tccccgtttg cagattcacc agatagcatt gttgcatctg tgccatcaaa tacagcgtta
     7021 gcaacgtcag aagcttccgc acgtgttgga cgtgggtttt cttgcattga ttctaacatt
     7081 tgtgtagcag tgataactgg gataccagca gcattacatt ttttgataat gcgtttttga
     7141 accattggta ctagttcagc tgggatttca acacccatat ctccgcgggc aatcataaca
     7201 ccgtcagaaa ctttgatgat ttcgtcaatg ttgtcgatac cttcttgaga ttcgatttta
     7261 gggaagattt gaacatgagt catgtctttt tcttctaaga tttcgcggat atctagaacg
     7321 tcttgtgctt tacgtacaaa acttgcagcg ataaagtcga tatcgttgtc taaaccaaaa
     7381 cgaatatcgt cagcatcttt tggagtaata cctggcaaac taatagaaac gcctggtgca
     7441 tttacccctt tacgtgatcc tagcatacct gcatttttaa cttctacgac taattcacgg
     7501 tttgcttcgt ctttttcaat gatttgcata tcgatcaaac catcatcaaa taaaatgtgt
     7561 ccgccaacgt gaacatcgtc aaataatcct gggtaagtaa ccgcgatttt ttcttttgaa
     7621 cctacatgtt caggatccat agagatgcgt gtttgatctc ctacttcaaa tttgatgtat
     7681 cctgcacgac caaaatcagc ttctgttgtg ccttgaacag ttgtacggat ttcagctcct
     7741 tttgtatcta aaagaatacc gacatctttt cctgtctttt taactgcttc acggaccata
     7801 gtcatacgtg ataattgttc ttcatggtca ccatgagaaa aattaaagcg gaagacattt
     7861 gccccagatt caatcaattg agaaataatt tctactgagt tacttgctgg tcctaatgta
     7921 ctaacgattt tggttttttt catttaaaaa actctcccat tcaattttgt ttatttaaag
     7981 ctgtacacag cttaaatagc ttggtttctt tcactcttaa aatgaaagtg aattatttag
     8041 atcatatagt gataagtctg gtttatgttt gttgttttca agtgtatcaa tgatgtcaga
     8101 cgcaacgatt tcgttgtcat ggataccgac acataatcca ccttttcctt cttgaagcaa
     8161 ttcgacagcg taagcaccga atttacttgc caacacgcgg tcgcgtgcgc ttggtgctcc
     8221 accacggaca acgtgtccca agatagatac acgtgtatga tagtcaccaa attctgaaag
     8281 tttctcagcg aattcatttc cgcccattac accttcagcc aagatgatca agcaatgttt
     8341 cttcccgcga tcgcggcctt cttggatttt tttagcaact gaagccatat caaaatcatg
     8401 ttctgggatg atgatttcat ccgctccgcc agccacacct gaccataaag cgatgtctcc
     8461 tgcattgcgt cccattactt cgataacgaa tgtacgaaca tgagaagtcg ctgtgtcacg
     8521 aatacggtca attgattcta gtactgtatt gattgctgta tcaaaaccga ttgtgaaatc
     8581 agtcccagga atatcattat cgattgttcc aggaatacct actgctggga aaccgcgttt
     8641 tgtcaaagcc attgcgccat gataagagcc gtctcctccg ataaccacta gaccttcgat
     8701 tccgaatttt ttcaattgtt cgattccttt taattgacct tcttcagttg caaattctgg
     8761 ataacgtgca gaatacaaga atgtaccacc acgttggatc ttgtcaccta catctgccac
     8821 atcaagacga cgaatatctc cagcaactaa accggcaaaa ccataattga tcccgtatac
     8881 ttccagtcct tcgtaaatac ctttacgaac aacggcacga acagctgcat tcattccagg
     8941 tgcgtctccg ccactggtca aaattccgat gcgtttcata ataaacattc acctcattaa
     9001 aatactttat cctaagtatg acttaggttt acaaccattt ttgcgttaac cacgactaac
     9061 attctaacat tatttttctc acttgtcttg atttacggat aaaaaaatga aaaaaaatga
     9121 aagcaagtag tattttttac cgtaagttat ttgaaaacca cattatcttc gccaagcaga
     9181 taaataagtt gccgctttat actcttgctg tcatccaccc aataagcatc tgacagaact
     9241 acttttcgtt gcgttttttc gtgatacata actactggta tatatcctgg gtgtttctga
     9301 aaaatcactt gtaattgttt cattatctcg ggatcttccc gttcttctgt aatacgcaaa
     9361 tagcaagttt gtgaaggata ctgggcttct aactggttag gatcagcaaa gctttctcca
     9421 attagttgca gttcctgatt atatttgctg atttcgctcc gcccttgaac aaagatcact
     9481 cgatcaacgg caaacaaatt acgatattta cgataaagag ttggaaaaac tgtgacagaa
     9541 atttctccac tactgtcggt tccttcaaca aaggccatca gttctccttt ttttgtccga
     9601 atttctctaa cttccttgat catcactaat aaattgactg gttgattagg gacgatatct
     9661 gtaatcagct gaacttgttt agctaaacga agacgatcaa acccttctgc aggatgacct
     9721 gacaaataaa tacctaagta ctcctcttcc agcttcaagc gttcttctag tgtatagtca
     9781 gcgacttctt cttcttttaa tgccatgatt cccagcaagt caagacttcc accactgtaa
     9841 acgatatttt ggatttttcc ttcgagatca agcatcaatt gtttcctgtt aggagataat
     9901 tcatcaaaaa ctcctactgc tgtcagtgat tgcagtaact ctaatttcag ccaacgctta
     9961 tcgatccgta tgaggaattg atccactgac tggaacgggc cattttgttt tctttcgttt
    10021 aatatatctt ctacaaaatc acgccgaata ccttttatcg ctgtcagtcc gaatctgatt
    10081 tcttccttat tgaccaactc aaaactggaa ttactttgat taatggacgg cgaggaaagt
    10141 ttgagtttat ttttacgtgc ttctgcaata tattctttca attttgatgt gttatgccga
    10201 acagaattca tcaggctggt aaagaaagca cctggatgat gggcttttag atacgccatt
    10261 tggaatccca cgaatgaata agcaaatgca tgtgaccgat tgaatccata gtttgcaaat
    10321 ttttcgatat attcatatac ggtcgctgct gttttttccg aatatccctg ttgtaatgct
    10381 cctgatacaa aatgcgactt ttcttcatct aatacgtctt ttttcttttt actcactgcc
    10441 cgtcgcagaa tatctgactg ccctaatgta aatccagcca tagtcgaggc gatctgcatg
    10501 atttgttcct gatagacgat cactccatat gtgtttttca aaatcgggat cagtgaatca
    10561 tctgggtagc gaatggcttc ttttcctttc ttcctggcaa tgaaggtatc tatattttgc
    10621 atagggcctg gtcgatacaa tgcattgact gcggcaatat cttcgatgtt ttctggatct
    10681 aatcttcgta aaacgttccg gataccagca gattcaaatt gaaatactcc tgaggtttcg
    10741 cctcgttgaa acaagagcag cgtttttgca tcatttagcg ggatctcttt taatcggatc
    10801 tcataccctt ctactcgctt aacagctttc aaagtaaaat caataatcga taagttgcgt
    10861 agtcctaaaa agtccatttt caaaagaccg attgcttcta cctcattcat cgtatactgg
    10921 gtcagaaaag cttcatcaga accgcgttgg agcggaacta gttcaagtag attcttatcg
    10981 ctgataacta cacctgctgc gtgagtcgaa acatgtcttg gcaatccttc taaaatcact
    11041 gcagttttga ataaaagttg gtttttttcg cttgcctgaa ctaattctac taattgatgc
    11101 gaagttttat aagcttgggt caatgtgatt ttcaattgat tgggtattgc ttttgaccag
    11161 cggtttgctt cactttgcga taaaccaaac actctagctg catctctaag aaccattttt
    11221 gctgccattg tgccaaatgt tgcgatttgt gccatatgat attgtccata cttttctcga
    11281 acataattca atacttcttc acgtcgattg tcaggaatat ccaaatcgat atctggcatc
    11341 gtaaagcgtt cggggtttaa aaagcgttcg aacagcaaat catattctaa tggatccaca
    11401 tctgtgattt ctaacacata ggctactaat gaacccgcag cagaaccacg acctgcaccg
    11461 gtaacgattt tgtttctatg agcaaaagcc attacatccc atacgatcaa gaaataatca
    11521 tcgaatccca tttgatggat gacagataac tcgtagtcca aacgttcttg gtattccttt
    11581 gtatagtcag tgattcggcg ttccacttgc gaatagcata actctcttaa atattctcca
    11641 gcttgttttc cattaggaac tggataatgc ggaagtaatt tctgatggaa ctggaattca
    11701 aatgaaatcg attcagctaa acgctgggcg cctattacag cttgggaaag acccgctttt
    11761 tcgaatcgtt tgatcatttc ttgttctgaa agaagataga catttgctgt tagtggtaaa
    11821 gatgcagata aattttctaa aggtatttgg cttccctctt tgatatgttt catcacttca
    11881 agtgcaaaaa gttcttcttg ttgtaaacta gcgatgggat gtaatgcaca aagcgaataa
    11941 ttttctttta tcacatactg ataccattca ggcaattgat caggcgtgtt ttctgtcaag
    12001 ccgatataaa aatttctagt aaaaacattt tcaagtaaaa actgccaatg accgaaaaag
    12061 ttatcctctt tattgaaagc ctcagaaaca gaatgatttg ccggaacaac aaacgctaga
    12121 tggtcggttt ctgtcatttc tgcaagttcc aatttttctt ggatcatttt tcggctggaa
    12181 agtttcatca gctgctgata acctatttca tcttttgcgt acgcaagcaa gccataattt
    12241 ttttcttcat aagtataact aagatgtaat ccaatgattg gctgtactcc ttcttctaca
    12301 caaatacgat agaattcagg tgcaccgtat aagacatctt tatccgttat ggctaatgaa
    12361 gtgtagcctt gtttttttgc ttcttgtaca tattctcgaa tacgtatcgt actttgtaaa
    12421 agagaataag aagtaattgt ataaagttgt gggaaaaaca tcttgcattc cgcctttttt
    12481 ttcgttaaaa ttcactagcg ttaaaaggtt tgatcctttt actttcatta agatagcagg
    12541 cgctgaagtt gattattcca cttcatttgc ttgcttgtaa tctgtaggaa tgagttcttt
    12601 cgcaagaact caaattttat tgagatttgg tctcgtttct ttacattcaa agaaaatctg
    12661 gtaaaattaa gatagaaaag aggtgttctt tatgcgatat atcgttacat tattctgggc
    12721 tgtcgttcta ggtcaagtag tcggttatat tggtgctgca ttaacaagcg gaacatatga
    12781 ttttactttg acaacaatca tttcattcat tgcgggtgtc attatccttt tgattggtgc
    12841 agttgcgcca agaaaagaaa cctctgccca ttcgtaaaaa aacagccaag agcttgagat
    12901 ttctcaagct cttttttatt ttctactcct caccaccatt ataatctgct gcgaagaact
    12961 ttacgaaagt tgaataaaga aagaagaata tttgacagaa caaacaaact tgtcacaata
    13021 aaaacagcac tgtaattata agcatgcgcg actgtcgatc ctagcatggg acctaaaact
    13081 tgtccaaagt tgctaaacat ctgattgtag ctatagattc ggctgactcc ttcttgaggc
    13141 gtaatcttac tgatcagtgt attgacagaa ggcatcaaag cgccagttga aaagcctaaa
    13201 ataaagcgaa gtatacctaa ttggagcggt gtagtgacga atgccatagg taaataacag
    13261 caaaatgata aaatgagtcc tccaattaga actttttgat tcccaatctt atcccctagt
    13321 tttcctagtt tcggtgaaga aaagacagcg gaaacaccag ctatcgaaac aatcaagccg
    13381 ctgacaaaaa ggatattttc tgtacttccg ctcaattcac gaatatataa ggtcaaaata
    13441 gggctgatcg tagtgattcc tatctgtaaa atcaaggtcg taatgaaaag accgatcaaa
    13501 atagagagat gatccatttt tgaaaaaatt tctttggtgc ttatcagatc ttttttctcg
    13561 attggatgga aatcttcttt gactaagaaa atggtcaata ccgttgtgat catcaacaaa
    13621 gcccctgtga tcaagaatac attttccata ccaaaccact gagccagtgc accgcccatt
    13681 gaaggtccga tcagatttcc agcaatcgct ccggtagaca atgttcctaa cgcccatccg
    13741 ctcttttctc taggtgcctg tgaagcaatc atcgctgtgg catttggaat atatccagac
    13801 aaaatcccat tccaaaaccg catgatcaaa agccaatacg cgtttggtac aaaagccaaa
    13861 gatcccattg ttaatgtcat ccctgctgct gcacggatca tcatgagttt tcggcctttt
    13921 cgatcagcta gatttcccca gattggtgca accacggcag atgcaaaagc agtcacagag
    13981 attgctagtc ccgaaaacaa ttcgatttga tcttttggtg ttcctagttg ctcaacataa
    14041 actggtatga atggcataac taaactaata cttgcaccag tgaaaaaaca gccaatccac
    14101 gcaatcacta aattttttct ccaattaatc tccatctatc atccctcttt cgtctctttt
    14161 atcataccta ttttcgaata aacaagcaac gatctcgcca gtaaaaagag aaaaatcccg
    14221 caaaggtcat tttatatgta acgttctttt tatgtaaaac aaaaagagat cagaacaaat
    14281 actgttccaa tcccttctct ttagttaaat tgttgctaga atgatgaagt tgataatgaa
    14341 taaaatatca acgatccaca aagcaacaga aacttgattg tattttcctt tgattacttt
    14401 cacaattgta tagaaaataa atcctgctgc aatcccatag gaaatgctat agcacaatcc
    14461 cataaagatc gatgcaaaga aggccggtaa agcttcttcc atatctagcc atttgatgtc
    14521 tgcaaaagaa gccatcatca ttactccaac taaaatcaat gctggcgcag ttgcttgatt
    14581 tggtacaatg gcgatcagtg gagagaataa actacttaat gcgaatagca ctgccactac
    14641 tactgaagtc aaaccagtac gtccaccggc cccgatccca gctgcagatt cgacataagt
    14701 tgttgtattc gatgtaccaa agatagcccc cacagaagta gcgatcgcat cggcaaatag
    14761 tgctttatcc atttttgttt tgaacccacg accatcttcc aacgcgatct cgtcttcttt
    14821 tgagaaaata cctgtgcggc gtcctgtacc gataaatgtt ccgatcgtat cgaaagtatc
    14881 agataaactg aatgcgatga tcgtcatcaa tacttgagga atcttggaag aatcactgaa
    14941 taaagattgc atgccttcag aaccaaatgc tgcaccgaaa gttgttccta attctttaaa
    15001 tgaattacct aacgaattcg tttgccaatc aatggaactt aaatcaacaa cacccataaa
    15061 aataccaagg actgtggtcg ctacgatacc gataagaata gccccacgga cattttttac
    15121 aactaaaatg gctgtcagta ccaaaccaat cacagccaat aagataggag cgttgtcaaa
    15181 gttggctaac gcagggacga ttccaccatt tatcgtaaca tttgtcgctt ttccgccttc
    15241 aacgacagag ctcgaaatag ctgactggtc tgctgaaaaa gataagaatc ctgcattttt
    15301 gattccgaca tacgcaacga aaataccgat cccgccacca atcgcatgtt gaagactttc
    15361 gggaatcgcc cgaataatca tttttcgaat atttgtgaca gtaataaaaa tattgattaa
    15421 tccgcaaata aacaccattg ccaaggcttg ttgccaagaa taaccaagcc caaaaacgac
    15481 cgtaaaagtg aaaaatgcgt tcaatcccat accaggtgcc tgagcatatg gtacatttgc
    15541 gaacaatccc attaccagcg taccaataat cgatgcaatg attgtcgcta gaaatactgc
    15601 ttggaagggc atacctgatg ctgacaaaat cgtcggattt acgaataaga tataactcat
    15661 ggcaaagaat gtcgttactc ccgccattat ttcagttgat acatttgtat tgtttttctt
    15721 taaaccgaaa aacttttcca taaaaagttc cactccctga atttttttct gatggaaaac
    15781 tataataata aaaaataagt aaaatagggc aaatccatcg aacaatttca aattatatag
    15841 acgtttcatt cgcttttcaa cgttttttta acaaaaaaag cgaaaataat acttaacgtt
    15901 cgtgtttagc ttatgtttag ctatttatat agccataact gtagtttttg ttaggaatag
    15961 ctgattgctc ttgttaatta cctaaaatat gctagactaa aacaaatgct agttgaggaa
    16021 ggaaggaccc ttattgaata aaaaattaat tgccatcgat ctggacggaa ctaccctcaa
    16081 tcaagattcg atgattacat ctaaaacaaa agagactcta aaaaaagcaa tcaatgccgg
    16141 tcatcatgtc agtattgcta caggacgccc attccgaatg agccatcagt tttaccaaca
    16201 attagaatta acaacaccga tggttaattt taacggcgca ttagtacaca tccctaatca
    16261 gcactgggat ggtgaaagag aaacgttgat caatcgtgaa atcgcttttg aaatcttatc
    16321 gcaaaaaaag cagctaaatt tagattttat cgctgctgaa aatcgtgata ctttttttat
    16381 tgacagtttt gatttctttg atgaaaaaat ttttgcttct tctcgtccag gagagaagaa
    16441 tttgctttct cctaaaaatt tgacgacaaa tcctacatct ttgcttgtcc gaacagacaa
    16501 acgttttgca ggagctgtat ctgctgaatt aacacgtcaa tttggcagtt atgtcgatgt
    16561 tcggacatgg ggtggaccta ctgccatctt agagattgtt tcaaaaggaa tccaaaaagc
    16621 aaaaggcgtg caagagattg ctaactacct gtctatcgat caaaaagacg tcattgcctt
    16681 tggtgacgag cataatgatt tggaattgtt ggattatgca ggttggggag tagctatggc
    16741 taacggtact gaccaactca aaggcattgc aaatgatgtc actcctttga gcaatcagga
    16801 agacggttta gctgtttatc tggaaaaact acttaaacta taatagagaa ttagattcca
    16861 caaaaaagag gttgtgacaa t
//
LOCUS       DAFELK010000060        16876 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFELK010000060
VERSION     DAFELK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.062"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..587)
                     /locus_tag="LP433_002309"
     CDS             complement(<1..587)
                     /locus_tag="LP433_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006444.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVF"
     gene            complement(735..1277)
                     /locus_tag="LP433_002310"
     CDS             complement(735..1277)
                     /locus_tag="LP433_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBL2006445.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            1412..1801
                     /locus_tag="LP433_002311"
     CDS             1412..1801
                     /locus_tag="LP433_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006446.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1805..2569
                     /locus_tag="LP433_002312"
     CDS             1805..2569
                     /locus_tag="LP433_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2006447.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2698..3645
                     /locus_tag="LP433_002313"
     CDS             2698..3645
                     /locus_tag="LP433_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2006448.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3775..4515
                     /locus_tag="LP433_002314"
     CDS             3775..4515
                     /locus_tag="LP433_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006449.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4806..5474)
                     /locus_tag="LP433_002315"
     CDS             complement(4806..5474)
                     /locus_tag="LP433_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2006450.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            5608..5895
                     /locus_tag="LP433_002316"
     CDS             5608..5895
                     /locus_tag="LP433_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006451.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            6311..7849
                     /locus_tag="LP433_002317"
     CDS             6311..7849
                     /locus_tag="LP433_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBL2006452.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7846..8811
                     /locus_tag="LP433_002318"
     CDS             7846..8811
                     /locus_tag="LP433_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006453.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8798..10120
                     /locus_tag="LP433_002319"
     CDS             8798..10120
                     /locus_tag="LP433_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2006454.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      10183..10287
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10361..11104
                     /locus_tag="LP433_002320"
     CDS             10361..11104
                     /locus_tag="LP433_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2006455.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            11119..12111
                     /locus_tag="LP433_002321"
     CDS             11119..12111
                     /locus_tag="LP433_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2006456.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            12123..12860
                     /locus_tag="LP433_002322"
     CDS             12123..12860
                     /locus_tag="LP433_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006457.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12850..13572
                     /locus_tag="LP433_002323"
     CDS             12850..13572
                     /locus_tag="LP433_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL2006458.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(13656..14279)
                     /locus_tag="LP433_002324"
     CDS             complement(13656..14279)
                     /locus_tag="LP433_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2006459.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            14674..15365
                     /locus_tag="LP433_002325"
                     /pseudo
     CDS             14674..15365
                     /locus_tag="LP433_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            15573..15863
                     /locus_tag="LP433_002326"
     CDS             15573..15863
                     /locus_tag="LP433_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006460.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         5765 a         2785 c         3432 g         4894 t
ORIGIN      
        1 ataaatacac ctagactgac gatgaagagc atatccaaca gatttcctgc gacttggatc
       61 gtcgaagggt tggtcagtgg cattaaagca aggacaaaaa aggaaaacaa gctgtaaata
      121 aaacaggtga caggaactaa tcgaaagaag agcggacatt tcaattggct aaaaatgagt
      181 gaaaaaataa aataagtaaa aatggataaa atcacgacta aaccattcat gataaagaag
      241 aaaagcgtat tgtgattaaa cgaataaaaa agaattgcta aaaaagaaaa cgttttaaat
      301 gcaatcaata cgcttgaagc ttcgtttaac gtaccaggat gtcgatgaaa aaaataggca
      361 ccgaaataaa cagaaaacag taagccgcaa agagaagaca aaatcaaaaa aaacggattt
      421 tcttcggctt ctgtgatatc agaatgatcc aaaagcaacc agcctaatgc actagaaggc
      481 gcatgtgagg tcttaaggta tgaataacat agaaaaaata agatcgtcaa agttgcaaaa
      541 aaagagccta aatgtaaaaa attagtggtt ctacgttgaa tttccataat atctccaaat
      601 taaattgata agtatataaa gtataataac aaattgatga gtatatgtcg atgtttttta
      661 atcaaaataa taaataaaaa ctgtctaaca tttaaaattt aatttagata ttagacagtt
      721 tttaagtttg tgagttattt tccttgtcgt tttctcactt ttttagtcca gaaaccacct
      781 gaaatatatt ttggctcata agaaatgata aaagcacgct cttcgatttc tttgatcagg
      841 cgatacagtt cacgttcgct ttttctagga gaaagtattt cgagaactag ccgctcacct
      901 tccagcccca ttgcagaagt ctgtgtcaca ccataaccgt gttctctcag tatacccggc
      961 aaacttttat cttctgcgct atttgctggc aaaatcgttg tgaccatgat gtatcctaat
     1021 gccaatttgt cttcaatcaa aattccgaca ctgataccta ctgcgtaacc taacgcatag
     1081 acaaataaat tcagtggatt atctaaacga tctaaaacaa gggataagcc gacgatataa
     1141 atcgtgatct cgaccatact gacaagtgga gcaatcagtc gatagccttt cattgtcaac
     1201 atgaaacgta acgtgttcag agtgatataa gcaaaattaa tgaggaagat catccccaac
     1261 atttttggat caatcatttg taaaactcct ttcatttata taacaacaat atcaaaaaaa
     1321 atcgtaagtg aagaaaaatt gaaactttat acatacaaaa aaatgataaa atgattataa
     1381 tagaattata aagataggtt aggtgattaa aatgaaaacg gtcaatcgtg tgttttgtgc
     1441 cagccacgtg ctaagtctcc ttctcagtat atacttaggt gtctattcga ttcaacagcc
     1501 aattgaggta gagaacattg tttttcagat gtcgctgaca gatggtttaa ttttaagcgt
     1561 ttttttcttt ttgatactgt ttattggtaa tattttcggt agcgttgcca gttttttgaa
     1621 tttttctatt tatccactcc tttcgctagc attaggagtg gtgggacttt gttctctgtg
     1681 cttatttccc gagccattca gtcctgcatt tatattattt ggtacactga acctgttcca
     1741 gacaactgtt ggagcatggt tgctatggcg atcaggaaat ttaatgaaaa taggtgagta
     1801 acaattgaat ccaattatat tgaaacgttc tgtccatcat attccagtgt tagaagttgt
     1861 tctgaaagaa ttaagagagg aacgtattcc cgttgtcatc tattatcacg gatggcagac
     1921 aagtaaggag ttagttttga cgcaaggaag aaaaattgcg cagcagggca ttcgtgtgat
     1981 cctgccagat gcgatgaatc atggggagcg caaacagccg gtttcttcta ttccatccta
     2041 tacattttgg gatagtatct acggaaatct gtttgaattt gacacactta tcaagcattt
     2101 agaaaaaaga ggtcttctac atgatcagct tgcagttggc ggggtttcga tggggggaat
     2161 gacaacatgc gccttgttgg ctaaacatcc tcatatagta gcgggcgtgt gtttgatggg
     2221 ttcccctgca cctttggaat atggaaaaga aatcgtaagg cgcgcatcgg aatataatta
     2281 tgtcgtacca aaagactatt ttgatttgat ttcatgggtt aagagctatg atttgtcatt
     2341 gcagccggaa aagttagctg gacgtcctct gttcttttgg catggacaag ctgacgaaaa
     2401 aatcccttat atacaaacgg aacgatttgt agaaaaaaat cggcataagt cttacggaaa
     2461 agaaattgtt tttcgttcct caaaaacaca gcgacatatg gtacaaatac cactaatgga
     2521 agaagcttcc acttttttag caaaaaattt gataaaaaag tataaataat tgaaacggaa
     2581 aatcactcat gacgatagag gattttccgt tttttatttt gggctataat aaactctgtt
     2641 aggaaaattt ggtataattg atagtaagaa tgacaacatg ttagaaagga agagagcatg
     2701 cccactttag cagatgttgc aaaacgtgcc aatgtttcaa aaatgacggt ctctcgagtc
     2761 atcaatcatc cggaacaggt gactgacgaa ttgaaagagt tagttttctc agcaatggct
     2821 gaactggatt accgtccaaa tattgctgca aaagcacttg tcacgaatcg gtcgcagatc
     2881 atcaaattat ttatactgga agaaatcgac acaactgagc cctattacat gaatttgctg
     2941 atgggaatcg ctaaacggat cggtaaagcg cattattctc tccaattagt tacaaatgat
     3001 gccttcgacg tcggttcttg tgatggatac atcatcacag gtgtcagaaa aaaagacttc
     3061 gattggatcg accgtttgga aaaaccagtt gtcttgtttg gggaaaattc tgaaggatat
     3121 gattatgtag acagcgataa tgaatatggt acagcaaaag caacgcaata tgccttagaa
     3181 agagattatc aaacgattat ttatatcggt atcgaagtgg acgagccttt tgaaatttca
     3241 agggaaactg gttatttatc tgtgatgaag gaagttgatc ttcctagtaa aatcttgcgg
     3301 tttccaaatc attcgacaga agtagaaaga tatatgacag aaaactgggc agattttaca
     3361 gataaaactt gttttgtatg tagttcagat cggctagcac taggagcagt aagagggatt
     3421 ataaatgctg gaggacactt gcccgaagaa tttggtgtga ttggatttga tggggtattt
     3481 ttagaccaaa tcagttcacc taaattgaca acgatcaagc aagatattat acgtatgggt
     3541 gaagtatgtg gagaaatgtt gttaaaaaaa atagaagaaa aaggggcgag tcaaggttat
     3601 cgtcgttttt ttcctgaact agttatcaga gagacaacga attaagtctt attactatat
     3661 atatatttat gaaattcatc gctattttct taaaataatc agcgcattgc tactgaaaac
     3721 aatgaatctg tgctattatt gagaaaagtt ccatttttga gaaggatggt ttgaatgaaa
     3781 gaaatcagac gaaaacattt ccgttttcct gcgtacgatg atgagttagg cgtaaaatta
     3841 accaacgaca agaagcgagt attatttgac ggacaagaag atcttttgac tgaacagaat
     3901 cagtccccgt ttgaacagat gaaagaattt catttcacga acacgaacac cgagaaaatc
     3961 cgtcgcaagc gtcgtgcaac aaatggattg aagtcagctc cgcgtaagga aaatttggaa
     4021 aagcataaag gaaaattacc ggattatacc ggccattacc aatcagaaat cacatcgaca
     4081 ggacgaaaaa aactttttgg tgattcctct cgttctgtca gacaaagtga aacaaggaca
     4141 gagtccaagc atactacacg aaacgcatct gttgacacga aggtgcggga gcgttcttat
     4201 tttgttccta aatatgtacc cgcatcgatt atcccagacc ctagagaaag caaaatttct
     4261 gaggatcatt taatcgaatc gatgaaaaaa acggatgact cttatctgtt gttcgataca
     4321 gaaccgacgc cgtatcaaga aaaaagaaat ggtgagccgt ctgtacgaac attcaatcga
     4381 acaaaaacgt tagaggaaac aaagcagtca gaagaaaaaa aatcgaaaaa aagccatggt
     4441 atcttagaac gctcattaca aggattgatc gatgatcaag gaaactcttt gggagaaaat
     4501 agctatttta aataagtgat atacaaattt atattcggct acagttggaa aggaaacgct
     4561 gcggcgtttc cttattttat actctatccg aaagtttata tcgtatcctc aaattttttt
     4621 gagtttaagc gaattttttc tcccaataag taagaaaata atggcaaaat aaaaaaacaa
     4681 actattttcg cagatcgttt gcaaaaatag tttatttttt tataaagaag attttactga
     4741 ataatatcat tttagtttac ataatgatat ttctgtaaat taaataaagt agtgaaaaat
     4801 aagaatcagt gctctaactg ttcaagagga tcaagtggtt caaatgtttc tgtagtctgt
     4861 tttgcttcca attggggcaa aacagatcca atttccagat acttcacttt attcaatgta
     4921 taagatagaa tagaacagct aagtaatgta tacagaaaat gtgtgagatc caaataaagc
     4981 aaggagacaa ctaaaatacc aaaagtaatc aagaaaagac ttttgccaat cttaatatga
     5041 aaatattttt caatggcttg ataaatgata tctgttccgc ctgtgcttcc gccgaatcga
     5101 aagacgagac cgcaaccaat gccagaaaga atacctgtca tcaaactatt gatcagtaga
     5161 ctatctacag caaaatgtat atgaaggctc tcccataaat gtaaaaagaa aactagcgca
     5221 aatgttccga cgatcgtccg gagaaaagcg tgttttccaa aaagaaacaa tgagataagc
     5281 aataaaggta aattaaaaag cagtgaagtg acagaaggag cgaatccaaa aagattatgc
     5341 aaaagcaaag caataccagt aaccccacca tctgccagct tagatggaat attgattcct
     5401 gtcacagcta atccgtagat tcctgcgcct aaaatgattc cgcacaattc tgtaaataaa
     5461 tttaattttt tcatttctag cctcttttct tttgaaaatt ttcagcaact tctttattat
     5521 actgacttat actcttactt caagaggaaa atgaaaaaaa attatttttg gctgtttctt
     5581 tttatttatc aaataaggag tggaaaaatg cgagcagcag acttattgac aattcttaca
     5641 aaatcaccca aaaaaacaga gtatcaagga gtttttttgg ctcaagaaca aaaactggtg
     5701 cctgtgacaa tggtccagat aaataaagca aatcaattta tctttttatt tgaacacggc
     5761 aaagcaccac ttgctatgaa agacatcttt ctttttttga tgaagaaccg tgagaaagct
     5821 gtttattatc agtcaaaaga agaactcatt cctctttatg gagtgaaaga gatagaaaat
     5881 aaagtggtga tataagtaaa aataagaaaa caagacgttt atgatgtcaa aacaaccatt
     5941 ttttacattt ttggcaaaaa agtgtcatga tacagtataa tattcgttga acaggccaat
     6001 aaaggtgttc tcccccacga gatttctact ttattggctg tttcttttta ttaaaataaa
     6061 agttgtgtgt gtaaaaaaga tatagctgat tccaagtgac aatttcgtat agatttttat
     6121 ggtattcgta gtgaaaaaac gagaaccaaa aagttgatcc gactttgttg cttggattct
     6181 ttttttgtca gcatatttag aggtattttt ttcttttttt tgttcgtgct gtaaggttaa
     6241 ggcaagacaa gttagttggg aaaaaggaaa gaaatgttta tacttaaaga ataacagaaa
     6301 ggaaggtcgc atgaataatt ttatacaaac attaagtgaa agaaaaggcg agttgctgga
     6361 agctgcattt caacatctgt ccatttctct catttctttg ctgattgcag cactgattgc
     6421 tattccttta gcgatttggg cagccaatca taaaaaaatg gcagaagtct tattgcagat
     6481 cacgggtgtg ctccaaacga ttccttcact tgccttatta ggtttactta tcccatttgt
     6541 agggatcgga actgttccag cattgattgc acttgttatt tacgctttgc ttccgatttt
     6601 ccaaaacacg tatattggtc tagctgaaat tgacccgtct attgaagaag cagcggtagc
     6661 atttggtatg tccagaatga gacgcttgct gaaagtagag cttcccatcg cattacctgt
     6721 cattatctca ggtatccgaa ctgccttagt tttaatcatc ggtacggcta ctttggcagc
     6781 attgatcgga gcaggtggat tagggacatt tattttgtta ggtattgacc gaaatacacc
     6841 tgttttgaca ttgattggtg cgatcagttc tgccttgctt gcaattatat tcagcggact
     6901 gattcgctgg ttgcagcata agaaacctcg atattccatc attactttag cagcagtggt
     6961 gtgtttattt ggcggcgttt ctttatatca gtctgccttg tttaaaaatg aaaccatcac
     7021 gattgctgga aaattaggag cggaacctga aatcctgatc caaatgtata aagaattgat
     7081 tgaagacaac acaaaaacag aagttgaatt aaaaccgaat tttggcaaga cgagtttttt
     7141 gttcaatgca ctggatcaag gtcaaatcga tatctatcct gagttcacag gtactgtcct
     7201 agaaagcttg gtgaaggtac ctgaagcaat gaaaagtgct gatttgacaa aagaaaaaac
     7261 atatgacgaa gcagaagaat tattgaataa gcaattcgat atgacattat taaaaccaat
     7321 ggcttaccaa aatacgtatg ccttggcagt caagagatct tttgcgaacg aacatcaact
     7381 taaaaagatt tccgatttgg cagctatctc tgatcagatc aaagcgggat tcacactgga
     7441 atttattgat cgttcagatg gatataaagg aatccaagaa gcatatggct tgaatttttc
     7501 aagtgtacaa agcatggagc caagtttgcg ttaccaagca atcaataatg gagatgtcaa
     7561 tattgtggat gcctattcca cagatagcca gctcaaggag tacgatctag tgactctaga
     7621 agatgatcga gggttattcc cagcttatca aggcgcaccg ctgatgaaaa aagattttgc
     7681 taaagaacat cctgaaatcg ttaaagcact gaataaatta agcggaaaaa taacagagga
     7741 tcaaatgatt gatatgaatt accaagtcaa tgtcgaaaag aaaaagccga cagaagtagc
     7801 acgaatcttc ctgaaaaatg aaggattagt aaaggaggaa gatcagtgac taaattaatc
     7861 gagttcaaac atgtgcaaaa aaagtatgat ggaaagtatg tcatcgatga cctaaatctg
     7921 gcaatcaaaa aaggagaaat ctttgttttg gttggtcctt ccggtagtgg aaaaacaact
     7981 actttgaaaa tgatcaatgg attatctaaa ccatcagcag gagacatcta cttcaaagga
     8041 aaatcgttaa atgaatataa tctgcagaaa atgcggtgga atatgggata tgtgctgcag
     8101 caaatcgctt tgttcccgac catgacagtc aagcaaaata ttgaagtcat ccctgaaatg
     8161 ttaggttggg aaaagcagaa aagagcagac cgtgtagatg aacttcttca aaaagttggc
     8221 ttatctcctg atatttatcg agatcgtatg cctagagagt tgtctggagg agaacagcaa
     8281 cggatcggga tcatccgagc tattgctgca agcccagatg tgattttgat ggacgagcca
     8341 tttagcgcat tagatccgat ttcaagaaac tcattacaag aattggtttt gtccttacac
     8401 gaagaattgg gcacgaccat cgttttcgtt acgcacaata tggaagaagc aatcaagcta
     8461 ggtgatcgta ttgcatttat gaaggatgga gaaattatcc aatgtgacac accagagcag
     8521 ttattgatga atcctaaaaa cgactacgtt cggcatttct ttgatgaacc gaaacagacg
     8581 aaagagtggc gagtagaaga tttagtcgtc aatggatatt tcttaaatga aataccagaa
     8641 aatgctcgtc aacaagtttg ctttgatacg cctatgaaag aagtatattc gcttctttcg
     8701 gtgtatccaa gcattgtgat agtagaaaag caaagaagta ttgggtcgct gacaagtaaa
     8761 gaaatctttg cttttttaag tcgagaggag gaaggaaatg aaaacatatg atgcaatcat
     8821 catcggttca ggtgtgagcg gcttaagtgc tgcttatgga ttgaaagaag caggtaaaac
     8881 agtactagtg gtcgaagaag atctatgggg cgggacttgt cctaaccgtg gatgtgatcc
     8941 taaaaaagtc ttgttaagtg cagtagaggc acgtaatcgg gtaaaacaat tgagtggaaa
     9001 aggttttaac gagatcccaa ctgccaactg ggaagaactt caaaaattca aacgaacatt
     9061 tacggatcca gtcccagaaa gccgaaaaaa acaattagca gaagctgaaa tcgatcatct
     9121 ttcaggaacc gctcgttttt tggatgattc atctattgaa gtcaacgaag aagtcttcca
     9181 tgcggattac ttagttttgg caaccgggca aagacctacg atcttaccag tggagggaaa
     9241 ggaatacttg aaaactagtg cagacttttt atcattgcct gtactgccta aagaaatcat
     9301 ttttatcggt ggtggttata ttgcttttga gctagctacg attgccaatg ctgcagggag
     9361 caaagtaacc attgtccatc ataatcaacg gccattaaaa gaatttgagg cgtctttggt
     9421 agaggaagcc gtccatcaaa tggaagcatc tggcattcag tttgcttttg gtgttgaaac
     9481 ccaaaagatc atttcagaag gtactcgcta tcgtttagtc ggaaaagaga cggaattagt
     9541 agcagatatg attttttgtg cgactgggag acagccgaat acagaatctt tagcacttga
     9601 gcaagcgaat atcgtctttg ataaacacgg aattgcagtc aatgattatc tgcaaacgag
     9661 caatccaaaa atttttgcgt gtggagatat tgtttcaagg aaaaccccaa aattgacacc
     9721 agtcgccact tttgaaggaa attatgtagc taagcggata acggatgcaa caagcgaacc
     9781 tatcaaatat ccgattatac ctacgatcgt ctacgccagt cctaaacttg ctgaagtagg
     9841 agttacaaaa agtcacgcct cttcgtcaga tcaagtggta gagatggatc ttaccagttg
     9901 gttcacctat catcgtgtca atgaaccagt tgctaaggct gaattgacct ttgaccagca
     9961 aaattatttg attggtgctg cagtgattag cgagcaagca gacgaattga tcgatgattt
    10021 gacactcgtc atcaatcaaa aattgactaa aaaagagttg gatagctata tcatggggta
    10081 tccgacattg gcaagtgatc tctcctattt attgaaataa tcagcatgat aactaaagcg
    10141 cttgttgctt tttccttctt gtgctacact ttaaaaaatg aatacctgtt tctggggatg
    10201 tcgtagacga catgagagta agttgtgaac ttagacccat tgaacctgtc agttaatact
    10261 ggtgaaggga gaaacatagc agacgcttga agcgggttac tatgtcgtgc ccatttcaag
    10321 cgttttttgt tattcatatt agaagaaagg aggtaacaaa atgaagaaaa atctttatcc
    10381 agcagtcagt atggcattca ttttaattat ttggcagatt gttgtcatag tttggaaaat
    10441 acctgccttt attttacccg gacctgctgc tgtattttct gcattagcgg cagatgcaca
    10501 agtattactt tcccattctg tcacgacatt aaatgaagca gtgcttggtt tggtaatagc
    10561 tagcgttctt tcttttatta ctgccttggc aatggattat tggaagtttt tagaaatgtc
    10621 tttttatccg ttactagtga tttcacaaat gttgccaatc atggtgttag ggccattact
    10681 taccctatgg tttggtttcg gtatgcttcc aaaagtgatc cttgttgtct tgataagcta
    10741 ttttccgatc gtagtttctt tttcggatac attgaggaaa gtatcaaaag agcaaatcat
    10801 ctttttgaaa acgatggggg cagatacagg gaagatttat cgaatatata aaataccagc
    10861 gggtttatcc ggcttctttt ccggtttaaa agtggctgct acttattgtg tcagcggagc
    10921 agtcgttgga gaatggctaa gcgctcaagc aggcttaggg tattacatga tacgcgtaaa
    10981 aaacagctac cagatcgata aagtttttgc tgcgatcatt tgtgtcattc tattgagttt
    11041 attgctgaat ggcgcttgtt cattattgaa aaaagggtat tatcgtatgc tttatatttt
    11101 ttaagagaag gggatcaaat gaaaaaatta tggcttttat taccgctact gttgctttta
    11161 tccgcttgtg gcactgcaaa agaaacaagt agcaaacaag aaataaagga tttgaaaaaa
    11221 gtgacacttg ttttggatta tgtaccgaat actaatcata ctggcatcta cctagcaaaa
    11281 gaaaaaggct attataaaga ggctggttta aatgtccaaa tcatcgaacc aggagataat
    11341 tcgacaagta ttggtctagt aggtgcggac aaagcacaat ttggtgtaag ttatcaagaa
    11401 gatgtcactt atgctcacgc agatggacag aatataccag tcaaagcaat tgctacagtg
    11461 atcaaacata atacttctgg attcgccacc ctatcagaca gtaacatcca ttcaccaaaa
    11521 gattttgaag gaaaaacata tgcaggttgg caaagtccaa gtgaagaagc tgtcttaaaa
    11581 gctgtgatgg aaaaagacgg cggggacttt tcaaaactga caatggtagg aagcaatgga
    11641 gaagggccag aaagcttagg aaaatcctca gatatccaat ggtactttga aggttgggat
    11701 atgatcaaag caaaagaagc gggtattgaa ctaaactata tcccattgaa agaattagat
    11761 gaacggttag attactatac tccggtaatt attacgaatg atcaactgat caaaagtgat
    11821 ccagaattgg tacagtcttt tatggatgcc acgaaaaaag gctatcagga agctattaag
    11881 gatccaaatg acagtgctaa actgttgcaa aaatatgcaa aagaaaatga tcggacgttt
    11941 ttagaagaat cacaagcatt cttgtcaaaa aattatacgg atgatcctga gaattgggga
    12001 ttgatggaag aaaaagtttg gcgcaattat acagctttta tgcaggaaaa cggattgatc
    12061 aagcaagatg taccttcgca agaactattc actaatcagt ttataaaata ggagtgatag
    12121 atatgtcaat ccaaatcagc cacttgaatg tagtcattga aaacctgaaa atattagaag
    12181 acatccattt cactatccct aaagatacct ttacatcgat tgtcgcgcca agcggagccg
    12241 gtaagtcaac attgctgaaa actttaacag gagtccagcc tatgacttct ggaacgatca
    12301 aagtagacga tcaaaaagta actggtctcc atacagcatt tagttatatg ccgcaagaag
    12361 atatgttact tccttggctg agcgtctatc aaaacgttac gttatatcaa aaaatcaatc
    12421 atctaacaat caatgaagaa caagtaaggg attatctgga tatctttggg ttaaacggct
    12481 atgaacattt tttgccggaa caattatctg gcgggatgaa gcagcgaacg gccttgttac
    12541 gaacaatcat gaatccttct tcttacttgc ttcttgatga accatttgga gcgttagatg
    12601 ctatgaccag agggcagatg caagactgga tgttgaagct gcctaaaaaa gcaaagcgga
    12661 ctactttact tgtgacgcat gatatcgaag aagcaattta tttatcagac aggattcttg
    12721 tgctttccgc ccgtccggca catgtgattg ctgagattca agtgcctgaa aaacgacggt
    12781 cacgtgaatg gctactgcag caatcagagt tgaagcaaac gatttatcag ttattggcag
    12841 gtgaattaga tgttaagtga tgctcattgt catttagatg ggagtcagag tttagcactc
    12901 cttcagcagg aacacacgat tttgacgatc atcaattgtg attcgccaga agaatggaag
    12961 gaaaacagac agcttgcagc aagtaagact caagccttaa gttacggtat ccatccttgg
    13021 aaagcagata gctatacgtt tgaacaagtt gagccttttt tgaaaaaagc aaggatcatc
    13081 ggtgaaatag ggttagataa tatttggacg aatgtaccga tgactacaca aaaaaaagta
    13141 tttgagcgac agcttgcttt tgcagccata aatgagaaac ctgttgtact gcacacaaaa
    13201 ggatgcgaaa aagagatctt aaattatatc caagcttacc ctaatcacta tttgatccat
    13261 tggtattctt ctttggacta tcaacaagac tatattgatt taggctgtta tttcagcatt
    13321 ggtcttgatt tgaaaaagaa tccagcagtc tggcaactag ctaaagcagt cccaatcgac
    13381 cacttactta ttgaaacgga tggactacat gcagcagagt gggctttagg ggggattttt
    13441 tcagaaaaag attatgtctc actgcttgaa gaacagttaa agacaatcgc tgagatcaaa
    13501 gagctatcag ttgaagaagt taaaaaaaat acttatcaaa acttggaacg tttcattaga
    13561 ttaggtaaat aaaaaagaga tgtgacacaa ctagtgtcgc acctcttttt ggctttcttt
    13621 gtataaaagt aaactgtttg attaataaat gaatcttagt accaaccgtt tgcttcccag
    13681 aatgctttcg ccgcttccca agaaccataa cgtgaagtaa catattgttc tgctactctt
    13741 tcttggtttg cagcagagta gtcaccattt aagtaagaag aatctaattg gtaacgtccg
    13801 atgtaacgtc cgttcgttgc tgtgtaagaa ccgcttgatt ctttttgtgc gatccattct
    13861 tttgcagagc ttgtgcttgc tggagtagca gcagtttctg ttacagcagg agcaggttgt
    13921 gtttcagcaa caggcgctgc ttgtttttcc gtttgaaccg tttcttgtac aacaggttgt
    13981 tcagcttgga ctggtgcttc ttgaacggct gcttgaggtt cagcagctgc ttgtgcagag
    14041 ccttctgttg ggattgttaa ttgttgtcct gagtaaatca ggttaatatc agaaattgaa
    14101 tttgattctg caatggcatt gatcaaggag ttatcaccaa cgtatttttg agaaatcgtt
    14161 gatagagtat cacctgattg aacggtataa gcttcgtccg catgagcagt cgttcccatg
    14221 aagaatgcag cgccggcagc caaagttgtt ccaaaaagta aagttttaag tgatgtcatg
    14281 aaaaatctcc tttattcgtt aaaaagtttt atttgttgtg ttcaacgagg aatactttaa
    14341 cacgtgaaaa tatttcatag gtaaaagaag catgacaatt tatgacaaat ccgcgttttt
    14401 tgtaataaat acagtaatct atgaaatgaa aagggttacg tttaataaaa cttgcttttt
    14461 tgtttttgtt caccataaat atttatttaa gaaagtatta acctgcattt ttctctataa
    14521 aaaagatttt ttaaatagat aaaaaaggag gattaaatga gtatttgata gtatttatat
    14581 taaaattaca tatgtaattt aaaaacgctt gacattgtgt ttgagatcac ttacttttag
    14641 catgtaaaag tattggatta aggagctatg caaatgaaaa agaaatttat tactggtggg
    14701 attgtcgttg catttctatg tctaattggc tacacaggca cgcggtacgc aaatgaaatt
    14761 attttgtggg gtggagagac agatattgat acaatcaatg agaatctgac acagcttgat
    14821 catacattga cagataaaga gcaagcgatt acagatctta ccgctcgact agcacaaaaa
    14881 gaacagacat tgcaagattc aaaggcagat gtccaagaat accaaacaaa agtaaatgaa
    14941 ttagaaaacc aaaaaaatca atcggcagca gaaaaacaaa acttagaaag tcaattagtc
    15001 agcaaggatg cacaactaca aagcaaacaa aatgaaatca atgtcaaact agatgagatc
    15061 aaccaaaaaa atgatgaaat caatcatctg aatgcagatt ggacagcaag actacaagaa
    15121 gcacaagcaa aactttcaga attacaaaat actgtaaatg gtttgaatca acaaatcgca
    15181 acactgacac aagaaaaaac aaatgtagaa atcagttaac agatacacaa aagaaattag
    15241 acgaagcaac tgctgaaaac tcaagcttga aacaatatat tcaaaagtta gaaaaagcaa
    15301 aagatgaagt ggaagataca gctgataaat ctcagcaaat tgttgaagaa catttgcgta
    15361 aataatcttt cttaacaagt aaacctaaat tagtaaagaa gcaacagtaa tctatactgc
    15421 tgcctctttt ttttagtaca tgtccttcat cttcgcagga agtgccaata tgattttaag
    15481 aaaggtaata gacaaaaagt caaaaagata aaacagagtt tcttctttac aaagggaatg
    15541 tatgttcgta taatggtatt gaggtgaagg ttatggagaa aaaatatgga acagtagata
    15601 agatccgtac tttgcaagtt agtgccagac cgttgatccg tttcagttta aatggggtca
    15661 attgtttgat tgcttcccat agtttgaact tcctagctga agtagacgaa gggatgaagt
    15721 tagtcgttac aggttattat aataatagaa agcaatttgt tgtgagatcc tatcatgtgt
    15781 tagggaaacc caaaattgtg gtagaatatg agaaaagtct atacccaaga aaaaaggtcc
    15841 gacaagatga aagaataaac tagaaaacaa gcggctgaga caaaaatgtc ctagccgctt
    15901 gttttggaaa gatggatgca gacgatggga tttgaaccca cacgagcata cgctcacaag
    15961 aacctcaatc tatatataac tacatgtatt taagtatttg tgatgaatca ctaaactttc
    16021 caaactcatt tgagggatat tgcttaaaga ttgaacagat caattcgaag ccctattagt
    16081 attcgctcaa tggggggatc agaggccata aaaagagact agtcattact agtctcaggt
    16141 agtggaattg taggatttta aacgttcctg gagagtaccg gtatgtaact cgaagaggtg
    16201 attatcatag tcgtaaaagt aaattgaaga agcctcgcct ttcacacgag aacgtcctgg
    16261 ttcgacagtt aaacctaaca tttggatttt tgagacaaac gaatctatat cttgttcgtc
    16321 aattttaaaa gcaatatgat tgtatgtctt tggcagttta ttcgacgaat tctgcattac
    16381 tgcaatccat aggtccttaa ctaagaaaaa tttttctgga tataatgaaa atttttttgt
    16441 tgactatcgt agatttcttt tgcatcaaat aaggtattta acaattaagt atttaaaaga
    16501 taacttttaa gttatcttta agtaatgctt aaagctatgt tatactctat taggaaatat
    16561 aagaaggagt ataaaaatga acaaacataa tagaaaaata acgaataaca aagaactgat
    16621 cttgttacta atagggattt ggggtatctt tttactcttt aatatgtata tgccgactat
    16681 gagagcggat gacgtagttt atgcaagtag attagatgaa cttggctatt tgggtgcttc
    16741 gatagaacat tataagacat ggagttcaag aattattata gaactattct taatgttctt
    16801 ttctaaacac tttatgctat ggaaattatt aaattctacg attatgttag gaattgtagt
    16861 attactttgc aagtat
//
LOCUS       DAFELK010000061        16782 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFELK010000061
VERSION     DAFELK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.063"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            72..2111
                     /locus_tag="LP433_002327"
     CDS             72..2111
                     /locus_tag="LP433_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBL2006461.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2220..3371)
                     /locus_tag="LP433_002328"
     CDS             complement(2220..3371)
                     /locus_tag="LP433_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBL2006462.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(3525..4055)
                     /locus_tag="LP433_002329"
     CDS             complement(3525..4055)
                     /locus_tag="LP433_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL2006463.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4154..4504)
                     /locus_tag="LP433_002330"
     CDS             complement(4154..4504)
                     /locus_tag="LP433_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBL2006464.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            4732..6006
                     /locus_tag="LP433_002331"
     CDS             4732..6006
                     /locus_tag="LP433_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HBL2006465.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTNQLFTILEDRRLYKLIQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            complement(6150..7679)
                     /gene="ahpF"
                     /locus_tag="LP433_002332"
     CDS             complement(6150..7679)
                     /gene="ahpF"
                     /locus_tag="LP433_002332"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBL2006466.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(7689..8252)
                     /gene="ahpC"
                     /locus_tag="LP433_002333"
     CDS             complement(7689..8252)
                     /gene="ahpC"
                     /locus_tag="LP433_002333"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBL2006467.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(8396..9058)
                     /locus_tag="LP433_002334"
     CDS             complement(8396..9058)
                     /locus_tag="LP433_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2006468.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            9242..10888
                     /locus_tag="LP433_002335"
     CDS             9242..10888
                     /locus_tag="LP433_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL2006469.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10879..11961
                     /gene="uxuA"
                     /locus_tag="LP433_002336"
     CDS             10879..11961
                     /gene="uxuA"
                     /locus_tag="LP433_002336"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL2006470.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(12069..13622)
                     /locus_tag="LP433_002337"
                     /pseudo
     CDS             complement(12069..13622)
                     /locus_tag="LP433_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            13770..14911
                     /locus_tag="LP433_002338"
                     /pseudo
     CDS             13770..14911
                     /locus_tag="LP433_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(15037..16116)
                     /locus_tag="LP433_002339"
     CDS             complement(15037..16116)
                     /locus_tag="LP433_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2006471.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(16219..16659)
                     /locus_tag="LP433_002340"
     CDS             complement(16219..16659)
                     /locus_tag="LP433_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2006472.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(16716..>16782)
                     /locus_tag="LP433_002341"
     CDS             complement(16716..>16782)
                     /locus_tag="LP433_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL2006473.1"
                     /translation="VCPYSKATAGNIEVTLKAVSE"
BASE COUNT         5735 a         3134 c         3054 g         4859 t
ORIGIN      
        1 ttttattatg ttagaataaa caggtataaa tagtgaaata aaggaatgac aagcaagaga
       61 aggaggaaaa aatgaaaaga agtgacaagc acggcaaaaa tcgaacaggc gcttatattg
      121 ccggcgcagt gatcttaata gcagctgcgg gtggcggtta tttttactac cagcactatc
      181 aagaaaccca agcagtagaa gctggagaaa agacagttga gcaatttgtc caagctttga
      241 acaagggaga ttataacaaa gctgcagaaa tgacatcaaa aaaggcggca aataaaagtg
      301 cattatctga aaaagagatc ttagataaat accagaatat atacggtgct gctgatgtca
      361 aaggacttca gatatcgaat ctaaaagtag ataaaaaaga cgattctact tacagttttt
      421 catataaagc aaagatgaat acctcattag gtgaattgaa agatctttct tataaaggaa
      481 cattagacag aaatgatggt caaaccacga tcaactggca acccaacttg gtttttccag
      541 aaatggaagg aaatgacaaa gtaagcctga ccacacaaga agcagcaaga gggaatatta
      601 tagatcgaaa tggtgaacca ttagcaacaa caggcaaact aaaacaatta ggagtcgttc
      661 caagtaaact tggagatgga ggcgaaaaaa cagccaatat caaagcgatt gcttcctcct
      721 tcgacttaac agaagatgct atcaatcagg cgatttcaca aagctgggta caacccgatt
      781 actttgtccc attgaaaatc attgatggag caacgccaga acttccagct ggagctacca
      841 ttcaagaagt agacggcaga tattatcctt tgggtgaagc agctgctcag ctgattggtt
      901 acgtgggaga tatcacagca gaagatattg ataagaatcc agaattaagc agtaatggaa
      961 aaatcggtcg ctcaggtttg gagatggctt ttgataagga tcttcgtggg acaacaggtg
     1021 ggaaattaag cattacagat gcagacggtg tagagaaaaa agttctgatc gaacatgaag
     1081 ttcaaaatgg caaagatatc aaattgacaa tcgatgcgaa ggcacaaaaa acagcttttg
     1141 acagtctagg aggaaaagct gcatcaactg ttgcgacaac gccaaaaacc ggtgatcttc
     1201 ttgcgcttgc tagctctcca agctatgatc caaacaaaat gacaaacggg atctcacaag
     1261 aagattacaa agcttatgaa gaaaatcctg aacatccatt catcagccga tttgcgacag
     1321 gttatgctcc tggatctacg tttaaaatga ttacagcagc aatcggtctc gacaacggca
     1381 ctatcgatcc aaatgaagtg ttgacgatca acgggcttaa atggcaaaaa gacagttctt
     1441 ggggatcttt tcaaacaacg cgtgtcagta gtgatgtatc acaagtagac ttaaaaactg
     1501 ctttgatcta ttccgataat atatatgcgg cacaagaaac gttgaaaatg ggtgagaaaa
     1561 aatttcgtac aggcttagat aaattcattt ttggtgaaga ccttgatttg ccaattagta
     1621 tgaatccagc acaaatttct aatgaagata gctttaactc agatatcttg ctagctgata
     1681 ctggatatgg acagggcgaa cttctaatta ctcctatcca gcaagcagca atgtattctg
     1741 tttttaccaa caatggcaca cttgtctatc ctaaattgat tgcagataaa gagacaaaag
     1801 ataagaagaa tgtcatcagc gaaacagcag tacaaacgat cgtgccagat ctgagagaag
     1861 ttgtgcaaga tgtaaatggt acagcacatt ctctttctgc tttagggatt ccgttggcag
     1921 cgaaaactgg tacagcggaa atcaaagaaa aacaggatgt aaaggggcaa gagaacagtt
     1981 tcttgtttgc tttcaatctt gataaccaag gttatatgat ggtcagcatg ttggaaaata
     2041 aagaagatga tgattcagca accaaacgag catcggaact attgcaatac ctcaaccaaa
     2101 attatcaata aaaaattgct ttttaagtac agtaaaagga ctgtggcgtt atcgtcacag
     2161 tccttttttc aaataaacgg ttttcacgat gtctctttca caacttcttt ttgatttact
     2221 cacacttcat aaactttttt tgtaaaatat ttgagaacaa gtggagaaat aagtgtactt
     2281 aataaaatca cgataactaa aggtgaatag tactgtggtt cgatcaattg actttgctgt
     2341 ccaatttgta aaatgatcaa agccatttct ccacgcgaaa tcataccagc accgaccatc
     2401 aatgaactat gttgagaaaa accggcaatc tgagcaccaa aataacctcc aagcaatttg
     2461 gtcaaaatcg ctacaagcgt caatatagaa ataaagagta gttgttcact aaagtcagaa
     2521 aaatcaactt ctaatcctac actgacaaaa aatactggta taaatactgc atatcctaaa
     2581 gcctctacat tgtggtatac ttcttcttta acctttgtct gactgacagc tatcccagca
     2641 aaaaaagcac caatgacaga gctaagccca acaagatccg ctacgtaaga cattcctaaa
     2701 caaataacta gcgatacgat gataatagaa gaatttgcgt acactttttc tgcaaatgaa
     2761 agtaggaaag gcgcaatcca tttgactaat aagaaaataa aaacaaaata aattagctgt
     2821 tcaatcaaaa caagcggtaa agaagcattg ctagaagctt cccccgttag aaaagatagg
     2881 ctgaaactta gaactaaaac gactaaaatg tcatctacca cagaagcacc caaaattgtt
     2941 gatccttctt ttgtattcac tacgtttagt tcttttaata cttctactga aatactgaca
     3001 gaagttgccg caagaataat cccaaagaaa atcgcttcat ttcccgaaac ttggaatgct
     3061 ttgcctgtca accagccaaa aacaaccggg aagatgatcc caagcaaagc aacgaacata
     3121 ccaggtcgga aatatttttt caaaagagat aaatcacttt ccagaccagc taaaaacatt
     3181 aataagatca caccaatctc cgaaaagtca tggactagaa tatcaggttt gacccaattc
     3241 aatccagctt ggcctagcaa aacaccaaca agtaattgtc caatcactgc tgggatacct
     3301 aatctccgcg agatatgtga gccaatcgtt gttgaaatca atatcaggca taaaatacca
     3361 ataaattcca ttctcatcat tcctttgtat aaaatatagc ccgaacttag cataacatac
     3421 attattgaaa aaataggaaa atatactcac aaaaaaacca acaatccaaa agattttttt
     3481 ggattgttgg tttttatacg gtctatttta ataactaaaa atgattaacg tatagtcatt
     3541 tttcttattc tgatgaaatt gataatctcc tggatgccca tgaaaatcaa aataaagccg
     3601 aatatttgga atagaagcat caaacttttg aatggattga acaataagac gaatccgcca
     3661 atcaacaaca gaatactact ataaacactc caacttttag cttttgtatt catgctgaag
     3721 aacaactgga acaagctgtt gatgataaca gctaatccaa gaagaatcgg caggatagaa
     3781 acgattgcag gtgcaaaagc atagacgatc agagctaaga tcaggaaaaa aagaccactg
     3841 aacagaccga tactccaaga acctgttttc cttttaaaac ggtaagcctc aaaaagattc
     3901 aacaacccaa gcaaaacaag ataggcggtg atcagataac cgataaaatg aaaaacagca
     3961 gaagggttta gcacaatcgc aatcccagaa ataatataaa cagcagctct taataaggcg
     4021 tatttttgaa tattttgttt aatcgtctca aacatataag aaaacctcct ttgacttatt
     4081 ttaacgtgaa ctagtcattt taccaaatta aatgttacaa aatgagcgaa ggagaagaat
     4141 atctctggaa aaatcaactt ctgaggatct tttccatttt tttgcctttt gctagctcat
     4201 cgatcatttt atctaaataa cgaatttctt tcatcaagtt atcctcgatg tcttctactc
     4261 gtacaccaca aacaacacct gtaatcaagg aacgtgaagg attggggaca ggggcttccg
     4321 caaaaaattg ttcgaaagtc acttgttttt gtagttgata ttctagttct gtttgggaat
     4381 aacccgtcag ccaacaaatg atttcatcta cttcctcttt tatacgatct tttctctccg
     4441 cttttgctac atacatagga taaacgcttg caaaacttgt cgtaaaaata cgattttgcg
     4501 ccataatcag tcacctttct ttttttcaaa ttatttacta cttatagtat ataagaaaaa
     4561 gagaagaaaa agcgattatt caaaaaaaca aaggttctat aatattttgt gttggtggaa
     4621 aatcgaaggc gattttctac taacactttt tcttcgtttc aactcaaaaa gagactcact
     4681 tttggtaaaa tttagtcgac caaaacgtca tcctaccaaa ggagtatctc aatggataat
     4741 catactagaa aattactcgg attaacagat aaacatttat tttttgatga agaatggctg
     4801 attgaaaaag aatataaagg cgttcaagcg cagtttatta aaggaaaatt ggatgactct
     4861 ccttcctatt gtgaacactg tcgatcggtt cgtattatcc gcaacggttc ctatacgaca
     4921 cgcactcaga tgttgaaagt caaagaaaag ttaactattt tagaattaaa acgtacccgt
     4981 tttctctgcc atgattgtgg aaggaccttt tctgcgaaaa cggacttagt tgatgaacat
     5041 catcaactaa caaaggaact gaagcaggca attctcatgg aactgtacga aaatcaatca
     5101 cgtaaactaa tcgctaagaa gtacttcgtc tcggatggga cggtgacacg gatcttgcgt
     5161 gaagcaacga agcattacca gtcacgtatg aacttccttc cgacggtgtt gtgtatggat
     5221 gagttcaaat caatgaagtc tgtttctggt tccatgagtt ttatttgtgt tgatgggaca
     5281 accaatcagc tatttacgat ccttgaagat cgcagacttt acaaactaat tcaatacttc
     5341 ctgcgctttc ctagaaaggc ccgtttaaag gtcaagtacc tagtgatgga catgaatgcc
     5401 agctattgtc agttgcttaa aacagtcttt ccaaatgcgg agatcgtaac tgaccgcttt
     5461 catattgtcc aacacatcaa tcgcagcttc aatcaattac gtgtccagat catgaatcgt
     5521 tttcgaacct cacactctga aaatcagaag aagtaccgtc ggctcaagcg atattggaaa
     5581 ctcttactca aagattccac gacatgggag ccactcaaac ggcattatca tcgactgttt
     5641 aaacgaccaa ttagtcaaac agaaatcgtt gatgagctgt taagctacaa cgaagaattg
     5701 cgaactgcgt atcatttttg tcaattatta cgctattatt tcgttaaacg aggtacggaa
     5761 ggctttcaag aaacccttaa aacaatttca tctacgttac ctcagtcgtt taaaaagaaa
     5821 ttcacgatct tccatcgcta ccaatcgggt atttcaaatg cctttaaggt gtcccactca
     5881 aacggcgtca ctgaggggct gaataacaag atcaagctga ttaaacgaat tgcgtttggt
     5941 tatcgcaact tttataactt tcgggcacgg atctatttac aacaaggtct gatctttgaa
     6001 aactaaaaaa atatgcggcg cacagaacgc gccgcatatc ggactaagtt ttattcaaat
     6061 ttgtcttcac caacacgatt tgacgaagag cccaaaattc ttgtcaccat ccttttttcc
     6121 gctctctgac tttttacaat cttcatagct caagtgcgca tcagataatc gaatgctcct
     6181 aaagctgcag tagctcctga acccattgaa acaatgattt gtttgtatgg actatctgta
     6241 caatcaccag ctgcgaaaac gccggggata ttcgttgcgc catttttctc ggtcactatt
     6301 tcatttcttg gattcatttc gatcgttcca tctagccaat ccgtattagg gagtaagccg
     6361 actagaatga atactcctga aacagctagt gtatgcatct ccatcgtacg gcgatcgata
     6421 taggagagag attctacctg attcgtaccg ctgatttctt tcgtcgctgc atgtttgata
     6481 acagtgacat tcgcaagaga gactagttta tcctgtaaga tttgatctgc ttttaattct
     6541 ggtaagaatt ctagaacata tacatgtttt gctaacccag ccaaatcgat tgctgcttca
     6601 acaccagaat taccaccacc gataacagca atctcttttc ctttaaataa agggccgtca
     6661 cagtgtgggc aataagcaat tcctttattt ttaaactctt tttcgcctgg tacattgata
     6721 gaacgccagt gcgcacctgt cgcgatgatg gcggtttttg ctttaagtga tataccgtta
     6781 gctaagccaa tattaataaa atgttgctct ttatttaagg aaacggcctg ttgattcatc
     6841 ataatgtcga tagggtaact acgcacatga ctttctactt gctgcatcaa ttttggacct
     6901 tctgtgtaag aggtaccaat catattttca atccctagtg tttcaacgac ttgtccgccg
     6961 aaagaatcag cgacaagtcc tgtacggatt cctttacgtg ctgcatagat agctgcacta
     7021 ctagctgctg gtccaccgcc aatcactaat acatcataag gttctttttc aaacaactct
     7081 tcttcaatca aagggccagt gattttttca acaatttgtt cgatcgtcat gcgtccgcta
     7141 ctaaattctt ctccatttaa aaacacagtt ggcactgcca tgattttttt atcatcgatt
     7201 tctttttgga acatcccacc ttcaatcatc gtatgagtaa tatttggatt taatacagct
     7261 aatatattca atgcctgtac aacgtcgggg caattatgac aagtcaagct aacataactg
     7321 tcaaaatgca atgtttgtgt tatttttttg attttaagac tcaaagattc actgattttc
     7381 ggtgcccgtc cactaatttg taacatagcc agtaaaaaag aggaaaattc atgaccgagg
     7441 gggataccag caaaaacgat tccactttct ttgccaactg gattgataga aaaactaggt
     7501 gtgcgcatcg aatctctttt ttcccaagag attttaggag acatttctgc tatttccttc
     7561 gtaaattcag ctagtttttg actattttca ctattatcca aactaacaga aaaaacaata
     7621 ggagattcaa tcagtgctaa atattgttcg agattttgtt tagtttcttt gtctaacata
     7681 tccaccacct aaatctttcc aacaagatca aaacttggtt tcaatgtttc gccactttct
     7741 ttccattttg ccggacaaac ttcacctggg tgggtacgta catattgagc agcgcgaatc
     7801 ttatcaatca gtgcactagc gtcacgaccg attccatctg cattgatttc catagcttga
     7861 acgattccgt ctggatcaat aataaatgtt cctcgctgag ctaatccttg ctcttcatcc
     7921 aaaacatcaa aaatacgaga aatctgatga gacggatcac cgatcatcac gtattcgatt
     7981 ttaccgatag catctgatgt atcatgccat gctttgtgag taaagtgggt atcggtagag
     8041 caagaaaaga cttcaacacc taaagatttc aatgtactgt attgttcttg taagtcttct
     8101 aattcagtag gacaaacaaa agtaaaatca gctggataga agcaaagaat actccagttc
     8161 cccataagat ctttttcact gacttctaaa aattctcctt gatgataagc atgtgcatta
     8221 aattcttcga tttttttccc aatcaatgac atagtaaaac ctccaataat aattatttat
     8281 ttataattat tgtaatttag ttggagttgc aaagtcaatg gatattttgt tatttaataa
     8341 agattactca aaaacgaagg ttaattataa aaatagaaga ggtcgcaaga aaatgctact
     8401 gctggaaata ctcgggataa cgttgagtaa cagtttcctg ttctttcagc atcatgtgta
     8461 agtgcaatcc cgtttgaaat cgagcttctt ctggtttttt atcaactaaa gccttgagta
     8521 aatcataatg ttgttccatg atcgtttccc atggaagccc ctgaatggtc actcgtaacc
     8581 agcggaaacg ttctaaatgg gtattatggt catctaacca gttccaaact tcttttcttc
     8641 ctgcaatttc gaaacaagct tcatgaaata aattatctgc acggaaaaaa gcgcgttcgt
     8701 catttatttt gactgctttt tcttgttctt ctaaaatcgt ttctagcact attcgtgttt
     8761 gtgtgtccaa tttggaacaa cattcaatca tgatttgctc ttccaactgt tctcggacaa
     8821 agcgagcatt ttctgcagaa acaagattaa ttttggaaac atacgtacca ctttgaggta
     8881 tcgtatacac gagttcttgc tgacgtagtt gaatcaatgc ttcgcgaatg ggagtccggc
     8941 cgatagcaag atgttcctcc agtgcctttt cagatatttt ccttccaggt tctaagtcag
     9001 catagataat ttgtttacga atcgcttgat aagcttgtga ttgcaagctg cttttcatct
     9061 ttattcctcc aaaatcattt ctatgaacgt agtataacag aagaggtctg aaaaacaatc
     9121 tggtatgtca cattaactag taaatttgta taaatagtaa aattttggtt gacatagcga
     9181 tttttattgc ataaaattca cttgaataca aaaactaata tgttagttta ggaggggaaa
     9241 aatgattgat ttaaacaact ggaggaactt tatccctgaa ttatctcaaa aagaagtaga
     9301 aatacctcat tttgaccgtg catcattaag agaaaatgga caaaaaaatc ctgtctggat
     9361 ccatttcggt ggcggaaatc tttatcgagg atttcatgca gaaatcgctc aacgtttagc
     9421 ggatctaggc gaattgtcca ctggtgtcat tgtttgtgaa acattcgatg aagaaataat
     9481 tgaaagggct taccaagatt ttgatgattt gattcttgaa gtggtcatgc caagcagtgg
     9541 agagttcgtc aaacgtatat tagctgcgac agctgacagt ctgtattgtc atccagattg
     9601 ttctgaacac tttgataaga tgattcgaca ctttgaaaat cctagtttac aattagttac
     9661 ttttgctatt actgaaaaag gttatcgatt gaaagataca aataataaat atataggacc
     9721 gattgcagtc gatataaaaa atggtccaaa gaagccatca catacaatga gtattcttgc
     9781 tgtgctactt tataaacgtt ttttatctgg agcttggccg attgcacttg tctctacaga
     9841 taatttttca caaaacggta gtcaattacg tacttctttg ctaacgatcg caaaagaatg
     9901 gcaaaaggaa ggttatgtac aaaatacatt tatccaatac ttatcgaatg aagaaattgt
     9961 tgcgtttcca tggacgatga ttgatcgtat caccccgaat ccttccttgt cagttagcaa
    10021 aatgttggca aaagagggct tttcaaatat gtcgattttc caaaccgcaa aaggaaataa
    10081 tattgctcca tttgtcaata cagaggacat ccattattta atcatggaag atcattttcc
    10141 caatggacgt ccgaaattcg aaaaagctgg ggtattcttg actgatcgtg caacggtaga
    10201 taaagcagat acgatgaagg tgacgacttg ccttaatcct ttgcatacgt ctttagctat
    10261 tatgggttgt ttactggggt ataggagcat agctgaggag atgaaagatc cagatttatc
    10321 gctgctagtt tctgaaatcg ggtacaatga aggcctccca gttgtggagt ctccaggtat
    10381 cattgatcca aagatctttc tggaagaagt aattactgtg cgcttttcta atccaaatat
    10441 tcctaatatg cctcagcgaa tcgccacgga tacctctcaa aaggtggcga ttcgttatgg
    10501 tgagacgatt aaaaaatata tggaaataga agttaaagac ccgcagacac ttgtattcat
    10561 accattgact ctcgctgctt ggcttcgata ccttattggc attgatgatc aaggaaaacc
    10621 attcatcccg agtccagacc cactattgac agaccttcag cataagcttt ccgatattca
    10681 actgggtacg caagatacat cacatattca tgagaaaatg gctcctattt tgtcaaataa
    10741 agaaattttt ggtgtagatc tttaccaagc agagcttggc agaaaaatag aagaaatgtt
    10801 catcaagatg gtagcaggac caaatgccgt acgaaaaaca ttacaggatt acttacaaga
    10861 acatggagga aatttatcat ggaaatgact tttagatggt acggatcaca ggaagaaaag
    10921 attaccttag atgaaatcag acagattcct gcggtcaaag ggattgtagg cacattgatg
    10981 gatataccag taggagaggt atggcctagg gagaggatca aagaactaaa agaagaaatt
    11041 gagtctcgtg ggttaacact aaaagtaatt gaaagcgtca atgtgcatga tgccattaaa
    11101 attggattac cttcccgtga gcagtatatc gaaaactata agcagacaat ccgaaacttg
    11161 gcagaatatg gaatagaagt catctgctat aattttatgc ctgtatttga ctgggtgaaa
    11221 tctgaccttg actaccgctt agaagacggc tcatccacgt tagcttttat atctgatgat
    11281 attccagatg atccaagaga aatcgtcgcg cgcatcgaac attccagcaa tgaatttgga
    11341 ttgccgggat gggaacctga gcgcttagct cctatcaaat ccttgcttga agcctatgca
    11401 tcagtagacg aagaaaaact tcgagaaaat tttgcctatt ttctccaatc aatcatccca
    11461 acatgtgaag aggtaggggt caaaatggct gtacatccag atgatccgcc atactcgatt
    11521 tttggattag ctcgaatcgt aaagaatcga gaagatttag attggttgtg tcgcatagta
    11581 gacagccctt ataacggaat cactctttgt acagggagta ttgcagaaga tccagaaaat
    11641 gatgtatatg ggattttagc agaattttgc caaagagatc gaatcccatt tgcacatgtt
    11701 cgaaatatta aatttttagc taatcgagat ttctatgagg caccacataa atccgaatac
    11761 ggttcattag acatgtaccg catactaaaa acaatgtatg acaacggatt taacggatac
    11821 atccgtcctg atcatggaag aatgatctgg aatgagacag gaagaccagg atacggctta
    11881 tatgatcgag cattaggtgc tgtttatcta aatggattat gggaagcaat cgaaaaagga
    11941 aacaaaagta aagataatta gtgaaaaaaa ctgtaatttt attatgtaaa taagaaggat
    12001 gttcaaattc ttgatacata aatccggagg ttgttaataa gcattcggat ttatgtatct
    12061 tatttggtct aggaagtaac ttgattttct tttttcgatt gatccatgag tgcttcttct
    12121 tttaattcaa agatatattc tgagatcctc ataatcactt ttttccagtc ttctggtgtg
    12181 atgattcctt ttaaaatata gatttttttg atatgagaag gcaattgttt caaagggcag
    12241 tcgctgataa cgatgttgca gttctccata aaatcatttt gtattttgat cgattcattt
    12301 gaaaaaattt gttctatctt aacgatcaga tctttactga tataaaaatc acgcgtatag
    12361 ttcacaccaa tcacaattcg cggctgtttt ttgtagcgat catacaaatg tactaggtct
    12421 tcaaccatcc attgcacatt ttccttttct aaaataactg gtaacaagtg ttgattttgt
    12481 tctctgaaat ccatataaaa ttgttcaatg gcggtttgga cttctttcaa tacgctatgt
    12541 tcttgataaa gcatgaaagt aggaaggggc gtatttggtt gattgaagtt aagaaatcca
    12601 ttataaagtt tatttcgtgc gaatgccaat gagtaaagaa tcttttcttt ttcaggtata
    12661 aacaaatcaa atacagtaca aagggactcc accatttctc ttgaataaag aacatgagga
    12721 acgtttgctt tttttaaaag tttgtattgc tccaagcttg tttcttccga ttcgattttc
    12781 gtgatagaaa gtcgagctaa aatattcact aagatgcgtt gttcgcgaca aattggcaga
    12841 ttaggtcgca aaatatctac agagagatca ataaaaaagt caatatattc atactctgtg
    12901 aattcttttt gtacgtcttt cacagaagtt gcaggaaaat tctctttaca tatttttaat
    12961 agaaaatata atttatctat cataccgcta tttagtcggt caagtacttc ttttttaaaa
    13021 aaagtattca tcataaaagc cactacttgc ggatcttcat cataaaattc tgtagcagta
    13081 cttgaaaaga tgttccaata aatatctaat gctgcatatt gaatttgtac ctcttttcca
    13141 gaaaaagact ttctgccatt attagaaaag gagatagaca aaccgtacta tgctaaaaat
    13201 gcattaatct ttttcatttt cgtatacaaa taagaggcac tatagtttgt ttgctgactg
    13261 aaactgataa tcgaatttgt ctgacagctg aacaaagaag tcaagatctg ataactgact
    13321 gattcgttgc agtatcttcc aaatagacga taatagcagt aagccggatc aattccttca
    13381 aaattcaact ttaaaaaagg tttttgctta tcaatatgca gttctgttag attgagacgc
    13441 tcaaagtctt gttctaattc tttgatgtat agtaaaaaat ttgattcaga catatggaaa
    13501 tgatctgcta aatattgtgt agtaataaag aaacgatgtt cagataggaa aagaaaaata
    13561 tctaattttg tattgctttt tttcttcaag ataaacgttt taatcgcttc ttgagtttgc
    13621 atgaaagagg ctccttttta cttaaattgt taaaacttga aaatattact gtttttttca
    13681 taaatttaga caaaaaaaca gtaaacatat aggtagaatc tctactatct tatttcttgc
    13741 atacaaaaaa atcaaggagt gagagagtta tgagatattc aaccatctta atatcaacat
    13801 ttgcagcctt aagcttatcg cttactataa atcagacagt ccacacagag gagacagaaa
    13861 cagccaaatg gacagaaacc aagtgggcca acgtcaatcg aattaccttt caggatgaat
    13921 tttcatcctt caattcagga gtcgcaaaat taagaaaagg acaaacagcg accatcaaag
    13981 caaaaattga ctattcggga gacttagcac ctatactaca atcagctgtt acatttgaga
    14041 atgttgatcc cactttgtcg attggctatg acgagaacac tttgactatc caacacaagc
    14101 aagcgatatt taccttcacc gttacattaa atcaggactt gttaaaacca gcgcttttta
    14161 ctgtcaaggt atcagatgga ctaccgaacg atcatcattt aacgccgtat agtcagcggc
    14221 agacaattga gcaagattca gccatcgact caggaggaga tcttgttgaa gaaccaacag
    14281 ataaaccaga aaatgaaaat aagccagaag taccgcctac agaaaatcca gacggagaac
    14341 agaaaccgga aatagaacct ggagaagaac ccgatacaga aactcaacca gagccagaca
    14401 ataaatcaaa acctgaaata acccctggag aaaaaccaga tgtaactcca gaaccagata
    14461 cggattctgg aaaccaaaca gtaccggaaa caaatccaga cacagataat gaaactgaaa
    14521 atccagaaaa accagaggta gatccagaag aaaaaccaga tgtgactcca gaaccagata
    14581 cggacgcaag agaccaagga ataccagaaa aaataaacaa aaaaacaatt caagaggatg
    14641 gaaaaaaaga gagtaaaaaa tcaaatctag caattctaaa aataaatgaa gagcagctga
    14701 ataaaaaatc acgaatattt gatagcgccc aatcagctga aaccttaaaa agtagcaagg
    14761 atacaacctt tgctgtcctg aaacgaaaaa taaacagcta ccaaaatccg gagagtcaca
    14821 aaacaaagtt atactgtgga gcggaatcat tctattaagt atagcaacaa tgctttctgc
    14881 aaaaagattt aaacaaaaca gatctctcta acatttgaat aatgtctgtg aacgcatttt
    14941 tcaaataaaa agaaatatcc agaaaatgac cccaaaatac cagattgaaa tctgatattt
    15001 ggggtcgttc atactttatc tttcttcata tttattttaa gggatatctg tttcttttgg
    15061 aagatggttc gggatctttt tcactttcaa tacatctaaa aagaaggtaa agatcggaat
    15121 gccgacaatc aagccccaaa cgccaaagaa ccgttcgcta acaagtaaga ccacaaatgt
    15181 ataaaaaatc ggcagttctg ttttgctgga catcaacttc ggattcagca cataagactc
    15241 aattagatgg acaatcaaaa tcgtaatcag gatataaaca acatctcgga tgcctccttg
    15301 ggaataagct atgaaagata gaggaataca agaaatgata acacctgcta ctgggatcag
    15361 acttaaaatg aaaatcatga tcgctaaact cagcagctga tgaaagccaa atacagccaa
    15421 ggcgattgta gtgagcaacg tatttaaaag agcgacaaca aattgagctt ctaataccaa
    15481 accaaatgta ttgacaaact tatcggcaaa atagtaaata tcttgaaaga accaagaaaa
    15541 ttcacttttt aaaaacaatc ttgagaatac aattgttttt ttcttttcaa tcataaaaaa
    15601 gaaacttaag atgaatgaca tagcaaacgc cactgccatt tttcctatat cctgtaaata
    15661 gccaagcgca atcgaagcgc cattttgaag ctgttcaaaa aaatcgtttc gctcaatata
    15721 agtatggata tattgtaaaa caggatctgc atcttttggc tgatgctcgt aaaaattaat
    15781 aacggactgg atcatgtcaa atgtttgatg aataagcatc gggatatact ttgtgaatgc
    15841 cagatagata aggtaaacga tcagtgtata aatcatgata gctaaaacac ctgtagggat
    15901 tcggacaaat cgctgaatga tttgaacaag atgaatcatc aaataagtaa agataaatgt
    15961 gagcaaaatg gttgtaatca tacttctaac taagaaaaga acaaaaacga caaataataa
    16021 aacagtgaga cggcgtattt tttcattcgc caaaaaacgc tgataaacgg tcaaatcgac
    16081 aacctccaaa taacaaaaaa taaacacgtt attcattata tgatggaata tgaaaataag
    16141 aaagagcaaa aagaaaaacc gctaaatgac gttatcttat gagttggttt tcctcataaa
    16201 atcgttcatc tagcagtttc agcccttttt ctggtcttga tgaaaattat ctagcatttt
    16261 tcgggtcaga tgttgcagtg tatccaattc ttcctgttca agtggaagat aagacttgat
    16321 cttttgtgga ataccttctg cttgtttttg caacgcagca ccttgagcag tcagcgtaac
    16381 atttacgatt ctttcatcac ccgtttcacg ctgacgatta atataatttt tttctgctaa
    16441 cttttttagt aagggagtca gcgtaccaga atccagacac aaatcatttc ctagctcttt
    16501 cactgaagtc tttttctttt cccataaaac taacatcaca agatactggg tataggtaag
    16561 attcagcggc ttgaggaggg gagtgtagtg tctaatgatt tctttagagg cggcatataa
    16621 aggaaaacat acttgattaa ctaaatatag atcttccatt tttccacctc cgctgtttta
    16681 ctatagtgta tcatagcgga tttacacaaa aaagtctatt cactaactgc tttcagagta
    16741 acttctatat ttccagctgt agcttttgaa tacggacaca ct
//
LOCUS       DAFELK010000062        16074 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFELK010000062
VERSION     DAFELK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.064"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            59..174
                     /gene="rrf"
                     /locus_tag="LP433_002342"
     rRNA            59..174
                     /gene="rrf"
                     /locus_tag="LP433_002342"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(227..697)
                     /locus_tag="LP433_002343"
     CDS             complement(227..697)
                     /locus_tag="LP433_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBL2006474.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(856..1314)
                     /locus_tag="LP433_002344"
     CDS             complement(856..1314)
                     /locus_tag="LP433_002344"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBL2006475.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1485..2629)
                     /locus_tag="LP433_002345"
                     /pseudo
     CDS             complement(1485..2629)
                     /locus_tag="LP433_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            complement(2642..3559)
                     /locus_tag="LP433_002346"
     CDS             complement(2642..3559)
                     /locus_tag="LP433_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBL2006476.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3987..4550
                     /gene="efp"
                     /locus_tag="LP433_002347"
     CDS             3987..4550
                     /gene="efp"
                     /locus_tag="LP433_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBL2006477.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4651..4821
                     /locus_tag="LP433_002348"
     CDS             4651..4821
                     /locus_tag="LP433_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006478.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            5036..6295
                     /gene="lysA"
                     /locus_tag="LP433_002349"
     CDS             5036..6295
                     /gene="lysA"
                     /locus_tag="LP433_002349"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBL2006479.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6282..7082
                     /gene="dapF"
                     /locus_tag="LP433_002350"
     CDS             6282..7082
                     /gene="dapF"
                     /locus_tag="LP433_002350"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBL2006480.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILGE"
     gene            7085..7966
                     /locus_tag="LP433_002351"
     CDS             7085..7966
                     /locus_tag="LP433_002351"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBL2006481.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7963..8679
                     /locus_tag="LP433_002352"
     CDS             7963..8679
                     /locus_tag="LP433_002352"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBL2006482.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8685..9380
                     /gene="dapD"
                     /locus_tag="LP433_002353"
     CDS             8685..9380
                     /gene="dapD"
                     /locus_tag="LP433_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBL2006483.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9396..10397
                     /locus_tag="LP433_002354"
     CDS             9396..10397
                     /locus_tag="LP433_002354"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBL2006484.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10394..11755
                     /locus_tag="LP433_002355"
     CDS             10394..11755
                     /locus_tag="LP433_002355"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBL2006485.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11715..12866
                     /locus_tag="LP433_002356"
     CDS             11715..12866
                     /locus_tag="LP433_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBL2006486.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12841..14010
                     /locus_tag="LP433_002357"
     CDS             12841..14010
                     /locus_tag="LP433_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2006487.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            14185..15564
                     /locus_tag="LP433_002358"
     CDS             14185..15564
                     /locus_tag="LP433_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2006488.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15845..16074
                     /locus_tag="LP433_002359"
                     /pseudo
     CDS             15845..16074
                     /locus_tag="LP433_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5254 a         2840 c         3429 g         4551 t
ORIGIN      
        1 tgacttcaaa tccagttttg agtgaacaaa atttactcaa taaaagataa caccacagtg
       61 tggtggcgat agcgagaagg atacacctgt aaccatgccg aacacagaag ttaagcttct
      121 tagcgccgat tgtagtgagg ggttgcccct tgtgagagta ggacgtcgcc acgcaaaggc
      181 aaaaagatga actagaaata gttcatcttt ttttattttt attaagttaa agaacggatt
      241 caattgcagc ggtcattttc aatggagaag tttgtggtgc aaatcgttcg attactttgc
      301 catttctatc aatcaaaaat ttagtaaaat tccattttat tgctttagtg acagtaccag
      361 gagcttcatt tttaagataa gtaaaaagag gatctgtatt ttctccattt acgtcaatca
      421 attgatgcat agggaaggta acgccataag tggttttaca agcttctgct gcttcagtcg
      481 ctgaatctag ctcttgttta aattgattgg aaggaaagcc taagataacc agaccttgtg
      541 tctgataagc ttggtaaagt tcttctaatt gtttaaattg aggtgctaga ccgcattttg
      601 ttgcagtgtt aacaatgatt atcggtttgc ctgcatattt tttcaatgaa tagacagtgc
      661 cgtcttctaa agtagtttca aaattataaa tagacataaa gttttctcct ttctatttta
      721 tataataaaa agagcgctaa actgaaaact agctatttgt tttcccgttt agaactcttt
      781 tcagacaata aatatttaat aaaatacgaa gataagatag ctatattgct tctcatcttt
      841 acgttctttt agaaactatg cttctacttc agaccattca tcgcgttttg ctaaaaattc
      901 acgagccaaa gcttgtgcac cttctagtgt atggctggca gcccagccac attgtgtttc
      961 attgcttgca ggtacttcag tagcttcaag aacatctttc attgttgctt caagaacatc
     1021 taaaatgtct tcgtagcttt catgattcaa tacagtcaag taaaagcctg tttggcatcc
     1081 cattggagac cagtctacga tgtaatctgc gtgattgcgg attagttcgg cagtcaagtg
     1141 ctcaagtgaa tgtagacttg gcatgtccat gtgttcttta tttggttgtt taaagcggac
     1201 gtcgtattta atgatgacat cgccatgcgc acccgttttt cgatcagcta cacgtacata
     1261 aggtgctttg acttttgtat ggtcaagatt aaaactttcg acattcattc tcatttgtaa
     1321 gactcctatc tgtttgttca ttcgttttga tgcttttcac taaagaatta tttagtgaaa
     1381 tttacaaaaa cgtctttcta cttgattcta acacttatcg tttccaaggt gtagcaatct
     1441 gaaatatttt ttagattttt ctgctaagtc gtttattggg acttctagtt cttgattctg
     1501 tcaaatgcct gagctaaatc gtttatgaga tcctgaccat actcaattcc tacagaaaga
     1561 cggatcaagc cgtcctttat gccagcctct tctcgttttt cttttggaat agacgcatga
     1621 gtcatgacag aaggaatttc cactaaactt tctacgccac ctaaactttc tgctaaagta
     1681 aatagttgga gtgattcaac aaatggaata gcagattctt cattttttaa agtaaaagaa
     1741 atcattccgc taaagccgct catctgctgc ttagcaactc catggagttc atgatcgggt
     1801 aatcctggat agtagacctt ttctactgct ggatgagaaa atagaaaatc agctaccaca
     1861 aaagcatttt tttgatgttc ctccatacga acacttagtg tcttgattcc gcgctgaagt
     1921 aaccagctat cttggggacc aagtacggct ccgatagcat tttggtaaaa tccgatctga
     1981 tcggctagat cttttggtta gaagtcacta aaccagctac tacatcgctg tgtccgccta
     2041 gatatttggt accgctatgg acaacgatat cagaaccgag atctaaaggt ctttgaaaat
     2101 aaggagtagc aaatgtattg tcagcaataa ctatcaatcc atgttgatga gccagagtgg
     2161 cacttttttc taaatcagta atctttagaa gcggattgct aggtgtttca agataaagtg
     2221 cttttgtatt gggtttgatg gattgttcta ttttatcaag attactcgta tctatgatcg
     2281 tgtactcgag accattttta gtaagaactt tgtcaaatag acggaatgtt cctccataga
     2341 catcatctcc taataagata tgatcgccag cttgaaaaag agaaaaaacg gcatgaatcc
     2401 cagaaagacc agaagaaaaa gcgaatcctc gaacaccgcc ttccaaatca gcaatcagtt
     2461 cttccaatgc aaaacgagta ggattaccag atcttgaata ttcatattgt ttaggctggc
     2521 cgacgccatc ttgccgataa gtggatgttt gataaatagg tacactgaca gctcctgttg
     2581 tgggatcttc actgatgcct ccgtggatca attttgtttg aatgtgcatg tttctttcct
     2641 cctataagta aatgtttttt gataaatagc ggtctgctgc gtctggaaaa atcgtaacga
     2701 cacgatgacc aggtggtaaa cgacgaattt ctcttaatgc tgctgcaaaa gccgcaccac
     2761 tcgaacttcc aactaatagt ccttgttctc gtgctaactg cctagtatag ttaaaccctt
     2821 ctacatcaga gattgtctcg atctgattga ttgaaagggg agaaagaaac ggcggaatga
     2881 attctacacc gataccctca atttcgtgag gggctggatc accaccattt aacacagagc
     2941 cctctggttc tacaccgatt attcgaatgt cgggatattt ttctttcaaa aaggtagaag
     3001 ttccagcaaa ggttccacca ctcccaattc ctgctacaaa actatggata ttttctttga
     3061 tttcatgaaa gatttctggc cctaacgtat gatagtaagc agcaggatta tctttatttt
     3121 caaattgaag aggcagatag ctgtttgata tctcctctgc aagtttttta cttttgctga
     3181 tggcaccgat gattccttgc tcactaggag aatggatgat ctttgctccc aatgctttca
     3241 tcaattgttg tttttctaag ctaaacttct ctggaacaac aaaaaccgtt cttaatttgt
     3301 atgtgagtgc ggccagagcg atcccaattc ctgtatttcc ggcagttggt tcgatgatcg
     3361 tcgttttttc attgattttt ccttgggcaa atccttcttt gatcaaataa ctgcccaatc
     3421 tatctttgat acttcctcca ggatttaaat attctagttt tgcataaata gcagaacctt
     3481 taggcataga atagtgctga ttgtcaaagc gataaagcgg tgtggaacca atagcttctg
     3541 taattgtcga gataatcatg tgggcctcct aaaaaaagat aataaaaaaa ggagctgact
     3601 attaaatcag ctccttgaaa gacatagaga aaaattgagt agataaaaag ataagttacc
     3661 tggtactcat tctatgaagg gcaattaata gacatgacaa atagtatgct gcttttatgc
     3721 accatacaac agcaacgatt caattgtttt tggttgctga ctgtcatgtg tatccctcca
     3781 agtaaaattt ttattaacga tagcatgaaa aaaaataaaa gtcaaaggct tgaaagaaaa
     3841 aaatatttcg atagcatcgt ttacccgtgt ttatttttct gacaaatagg catgagacct
     3901 taaaagatag agaatactct agttttctgg ccggttgtct gatacaataa agttgattat
     3961 gataaagaaa agaaggagca aaaataatga tctcagcaag tgatttaaga gccggtatga
     4021 ctttcgtaca agacggcaaa ctgattaaag ttctggatgc aagccaccat aaacctggta
     4081 aaggaaatac agttatgcgt atgaaactga aagatgtccg ttcaggtgca acatacgaca
     4141 caacgttcag accagaagaa aaatttgaaa aagcacatat cgacacaaaa cctgtacaat
     4201 atttgtacac gatggatgat acagctttct tcatggattt ggaaacatat gagcaatatg
     4261 aaattcctgt agaaacagta gaagaagaaa tgaaatatat cctagaaaac atggaagtaa
     4321 aaatccaatt tttcggtagc gaagtcatcg gcgttcaatt accaacaact gtcgtattac
     4381 gtgttgtgga aacacaacct tccatcaaag gtgcaacagt cactggttca ggtaagccag
     4441 cgacaatgga aactggctta gtagtcaatg ttcctgactt catcgaaaca gatgaattgt
     4501 tggaaatcaa tacagcagaa ggttcttatg taaaacgtgc gtcaaaataa ttcgctaacg
     4561 gattgataag aatttgaaaa cagagcttga cctcttgaaa ggcagatcat cggatctgcc
     4621 tttcaagagg ttttttgtgg aatcagcaaa ttgaaaaata aaaaagtatt tgattttatt
     4681 tatattttga aagatgaatg gcaaaagcta gagaaagaaa aaactgcact tatttatgaa
     4741 gaaattgaaa tgattcataa aattgaaaat atccgaacta ttccgaacta tattgaagcg
     4801 aaaatatttt ttcatcacta aatagtgttg aatttatgtt tttatgtata aatagcttct
     4861 aatagttcgg gtattttgtt tttataacca tttttattct tatttttaaa aaaatatttc
     4921 gaaatatact agacaattca gaaaattttg tttaatatta ttccaataaa attcaaatct
     4981 ttatcaaatg aaattccaat aaaaacggaa aaaaagtgaa aagaggaatg aaaaaatgac
     5041 agaattgata attggcggag tcacagcaag cacattggca gaaaagtata agacacctct
     5101 gtatgtgtat gatgaagaaa agatgagaca aacgatgctg tcattcaagc gaggctttgt
     5161 atcgaaacgt tttgatacaa aagtgcttta cgcctctaaa gcattccaaa cgattgagat
     5221 gctgcattta gttcgtgaat atggattcgg gctagatgtt gtcagtggtg gggaaatcta
     5281 taccgctttg caagctgatt ttcctagaga tactatctac ttccatggta acaacaagac
     5341 gccagaggaa ctgatctatg cacttgaaaa tgatttgttg catattgttg ccgataattt
     5401 gatggaagtt gaattattag cagaattaag ccaacgctat ttaaaaaaaa tctgtatcat
     5461 gcttcggttg aatgtcggag tagaagcaca tactcatgaa tatatcgtca ctgcgcatat
     5521 tgattcaaaa ttcggcatga gctatgaaag taaagagtgc caacaagccc ttcagttgat
     5581 aaaagaaagc agctatctag agttagaagg atttcatgct catatcgggt cacaaatttt
     5641 tgatgttact gcttggttag ctgaaatcga caaattgacg aattacttaa ccgattttga
     5701 ccaacctctt tccttgaatc ttggcggagg gtttgggatt cgttatacac aaaatgatca
     5761 gccgatccca gtcgaagagg cactaaaaaa actgattgaa tatacggaag aagctttgga
     5821 aaaacgaaaa ctgaccattc gtcaattact gatcgaaccg ggtagaagta ttgttggaga
     5881 agctggtaca acactataca cgattggttt catcaaaaag acaccacata aaaaatatta
     5941 ctttgtagat ggcgggatga cagataatat ccgtccagct ctgtatcagg cagaatacga
     6001 ttgtgattta gcagcaaaac tgtcggaaga aaaaacagag aaagtgacga ttgcaggaaa
     6061 aatgtgtgaa tcaggcgatg tggtaattaa agaagcttat ttgccgaaag cagaatcggg
     6121 tgatctttta gctgtttatt ccacgggagc ttatggatac tcgatgagca gcaactacaa
     6181 tcgagcgaca cgaccagcag ttgtttttgt caataatggc caatcaagac tgattgttcg
     6241 cagacaagca ttttctgatc tactaagggg ggaagtttcc tatgatcctt cataaatata
     6301 atggctgcgg aaatgatttt atcttattag attacgcaga agacacagat tatagtcaat
     6361 tagccgcttc tttatgcaca aaagaaaaat atgatataga cggattgatc gccgtaaaaa
     6421 tcgatccgtt ggaaatgatc tattacaaca aagatggcag ccgcgcgccg atgtgcggaa
     6481 atggcattcg ctgttttgct cgatacgtaa atgatcagaa catgatgaat gaacaggaat
     6541 tcaacgtaga gacattagca ggcacaagaa aaattacggt gttggatccc tcaccttttt
     6601 attgcagcgt agatatggga gtgccagatg attctccgga aaaaatcaaa gctaatcaaa
     6661 cttatccaat aaaaaaccag gaaatagaga tcaatggtga aaaagtaacg atcactagtt
     6721 tatttttagg aacgattcat accgttgttt ttgttgaaaa tgcgcgtgag gaagtctgga
     6781 gaaaaagagg tgaactgatc tgtcatcatc ctttgttcaa agaaaaaacc aatgtcaact
     6841 ttgtagaagt agtcaatgaa caagaattga tcgtccgtac ctatgaaaga ggagtaggtt
     6901 ggacacttgc ttgcggtaca ggttgctgtg cctcttatgt ggttgctaag gaaactggga
     6961 aaatttcagc agatcaggta gttgttcact tggaacaagg agacttgatg atctctggtg
     7021 aggatgcgat acaaatggct ggcccagcag ttcatgaatg gacaagaata ttgggggaat
     7081 gaagatgata aaaggttcga tcgtggcgct gatcacgccg atgaatgaag agggatcagt
     7141 agattatgct ggtttggaaa aattgatcca attccattta gatgaacaaa cagatggatt
     7201 attagtttta ggtacaacag gagaatcttc tacgctcaca caatctgagg aggagcagat
     7261 ccttcaactg acagtaaaga aagtggctgg ccgtgtgccg gtgattgcag gagctggaac
     7321 gaataatacg aaagaaacga ttgaaaaagc gaagcatttt gcttctttgg gggcagacgc
     7381 acttttggtc atcacccctt actacaacaa aacaagtgat gcaggactag ctgctcattt
     7441 tacagcaatt gcagaagcct caccgattcc gcttattttg tataatgttc cttctagaac
     7501 aggcatgtcg attccaatcc atgtattagt aaatttagca gaacatccta atatcattgg
     7561 tttgaaagaa gcctcaggag atatggctta tgtgatggat gccgctcggt tgattggaga
     7621 agaattcttc ctttacagtg gaaatgatga tttgatccta ccagtaatga gtgtaggagg
     7681 aagcggtgta ataagtgtat gggcgaatat ccaacctaaa atagtccatg aattagtaaa
     7741 agatacgcag gacggaagat ggcagcaagc aaaagaaaag caattaaatg cacttgaact
     7801 gatccatgcc ttgttcagtg agaccaatcc tattcctgtc aaagcagcca tgtcattatt
     7861 agacttacct tccggacctc tacgcctgcc tttagtttct ctttcaaaag agaaaaagaa
     7921 acaattagct cagcttttgt taaaagaaag gacggttgaa aaatgaaaat cggactgatt
     7981 ggcagtggac agatgggaaa tagagtcgaa gaagttgcac aagaaagagg agatacggtc
     8041 cttcttttac ggacggcacc taaagaagca actacgcttg cttttacgga actgccagaa
     8101 ctgcttattg atttttctca tccagataat ttagagaaaa tcctttcgta tagcttatca
     8161 tatcaacttc cgttagtcat tggcacgaca ggttatacac aatcacagtt ccaagaaata
     8221 aaagaacatg ccaaacatgt acctgtgatg tatagtgcta atttttcgtt cggcatcatg
     8281 gtgatgaatc aactaatcaa gcaagcagct gcaatgttgc aaggctggca gatcgaactg
     8341 attgaaaaac atcatagtcg taaaaaagat gcaccatctg gtactgcaaa tatgctgctt
     8401 caaacaatcc aagaagtgca aaagctgcag cccgtataca actggcaagg gaaaaaaaga
     8461 gaagaaaacc aaattggtgt acacagtatt cgtgcaggtt ctttacctgg tgaacatgat
     8521 gtattgtttg ctgctactga tgaaatattt acgatcaaac atgaatcttt ttctaatcga
     8581 atctttgctg caggcgcagt agaagcagcg gactggttga aagatcagtc accaggttat
     8641 tacaaattag aagatttatt aatggacaaa ggggtgtaaa aaacgtggaa gctcaagaaa
     8701 tcatccgcta cattcaaacg gcatctaaaa agacgcctgt gaaagtctat ctgaatgtaa
     8761 ccgagccaat cgaatttaaa gaaagtaaag tttttggtga aggaagcagc ttcgttgttt
     8821 ttggtgacta tgagacgatt gctccggttt tagaagctga atcagaaaaa atcattgaaa
     8881 tcgaaatcga aactgctgca agatacagcg cagttccttt gctagatatt aaaaaaatta
     8941 atgctcgtat cgaaccaggt gctattatca gagatcaagt gtcaatcggc aacaatgccg
     9001 tgatcatgat gggagcgatt atcaatattg gtgcagtaat cggtgaaaac acgatgattg
     9061 atatgggtgc tgtcttaggt ggacgagcga cagtgggcaa aaactgccat attggtgcag
     9121 gagctgtctt agcaggtgtg atcgaaccag catcggccaa accggttatc gtagaagacg
     9181 gcgtactggt aggtgcgaat gcagtgattg ttgaaggtgt ccatatcgga aaagatgcag
     9241 tcgtggcagc aggagcagtg gttttagaag atgtggcagc agaaactgtt gtcggtggaa
     9301 tacctgcacg tgtattaaaa ataagtgatg atcagacaaa agaaaataca gcattgattg
     9361 ctgcgttacg cgaattatag aggagatgga gaaaaatgcg cgaaatagat acctgtattg
     9421 tgggggcaac cggattagtc ggccaaacga tgctcaaagt gttagaagaa tatgattttc
     9481 cagtaggacg attgaaatta ttagcttcaa aacgttcagc cggtaaagtt tgtgtattca
     9541 agaaaaagaa acacactgta caggaattga cagaaacttc atttgaagga tatgatttag
     9601 cgctattttc tgcaggtgct tctgtatcca aagagtttgc gccaatcgca cgaagtcagg
     9661 gactatttgt catagataat tcctcagcat ggcgggaaga ttcggatatt ccattaatcg
     9721 ttccagaggt caatctggaa gactatacat tgaatcggct gattgcaaat ccaaattgtt
     9781 caaccattca agcggtactt ccgcttaaag ctttacaaga agcctttggt atccagcgag
     9841 tcaattattc gacctatcaa gcagtttctg gttccgggca aaaaggcatt gaagatcttc
     9901 atcgtacgca aaatgacgag gaaccagttt tgtatcctta taatattagc caaacggtga
     9961 ttccggaaat cgatcagcct ttggaaaatg ggtatacaaa agaagaacag aaaatgataa
    10021 atgagacccg taagattctg catcagcctg ctttgccagt atcagcaacc tgcgtacgtg
    10081 tgccaatcga aaatggacat ggagtctctg tggcagttca actgcaaaaa gagtttacga
    10141 cggaagaaat tagagagtgt ctcagccagt ttccagggat tcaattagaa gatgatctag
    10201 cagcacataa atatccgacg agcattcttg ctagaggaac agatatggtt tatgttggga
    10261 ggatcagaaa agacacttct ttagagaacg gattgttgtt ctatacgact gccgataaca
    10321 tacgcaaagg agccgctgcg aatgccgtac agattgctgc agctttaatg cagaaaatag
    10381 cggaggtggc aagatgagta atacgctgaa agtagcgaaa ttcggcggaa catcgatgtc
    10441 tcatgaagag caattcaaaa aagtccgtac aattgttctt tcagatccca atcgccaagt
    10501 gatcgttgtt tctgctttag gcaaacgtac gtcagatgat gacaaagtaa cagacttact
    10561 ttatttgatt tatgcttacc ttcagcatca tgttgattgg acaccccttt ggaaaaggat
    10621 ttgtgatcgt ttcattcaag taagagatgt tcttgccctg cagttaccta ttgaagatga
    10681 actagcacgc atacagaaac aactggaaga cgaaaagata actgaagatt atttagtaag
    10741 tagaggtgaa tatctgactg ctcaactgat ggctgagtat cttggttacc agtttattga
    10801 cgcaaaagac ctgattttct ttgactatga tgggaaaatc gatcaggaaa aaacagcaca
    10861 ggaaatcaca aaagcattta aaagatatcc gaaaatggtt gttccagggt tttacggggc
    10921 gaaccctgca ggaaaagaaa aattattggg ccgtggggga agcgacatta ccggcgcgat
    10981 actggcgaag atgttgcaag cggaaagtta tgagaattgg acggatgttt caggaatcat
    11041 gatggctgat ccgcgaatca tcgatcatcc taaaatcatc gaggaaatct cttttagaga
    11101 actgagagag atggcttata tgggggctaa cgttcttcat gaagcagctg ttttcccagt
    11161 tcaagaggct gatatcccca tccaaataaa aaataccaat gatcctttcg ctcaagggac
    11221 aaaaatatcg aatcacgaaa tagaaaagga aaatggactg acaggaatag ctggacgcaa
    11281 ggattttctt tccatcactt tattcaaacg tcatatgtcc gatgaaatcg ggtttatctg
    11341 gaaagcaatg agcatttttg ctaaacatga gatatcaatc gaacatattc cttcagggat
    11401 cgacaatatc ggagtgatcg tctcagcaga agcgattgcc gataagttat ttctcatcac
    11461 gaaagaatta aaagaaacac ttggcgtgga agaaatcgtc gtgatcgaag acttagcttt
    11521 gatctctgtc gttgggggtc cgcataaaga attgattgga ttatctggga aagtgttatc
    11581 gatattgaac aaattagaaa ttcgcacatc gatcttatca caaggagcac aggagttgaa
    11641 tctgatcatc ggtgtaccga ataatcaata tgaaacagta gtgaagggta tctatgaagg
    11701 gatggtgaat acggatgctg aaagaatatc gaatggcact ccatcaaatt cctgaaatcg
    11761 ggtttcatga attcaagaca aaaaaatatt tatatgaaca agtaaaaaac agcgaggccg
    11821 ttatccatga aatcggcgaa acaggactac tcctttattt tgataatcag caagaagaaa
    11881 cgattgcttt tcgaacagat atcgatgcac tgccagtcaa agaagaaacg aatctctctt
    11941 ttgcttctaa gcatgaaggt tatatgcatg catgtggtca tgacggacat atggcgatgc
    12001 ttttagggtt gactgacttt ataactaaac acattgagga tcttatttat aatgtagtac
    12061 tgatctatca gccatcagaa gaaatttccg gtggcgcaca aagcgttatt cagtcaggat
    12121 tgttggataa atatgaagta caagcaatat ttggctttca tctatggcct ggactagcta
    12181 agggagaagt tttctctcga ccaggacctt tgatggcaca aagcagtgaa acagacatta
    12241 tcattaaagg ccagtctgca catattgctt ctagtgaaaa aggaatcgat agtctggagg
    12301 cagctgtacg atttttgaag aatgtttatg attttgaccg gcaattaccg gcagagtgga
    12361 atcatctaat gaaatttggc caaatccaag gtggaacgat ccgaaatgtt ttagctggag
    12421 aagttattgt atccggaagt atccgttctt acagttcaga tatgcaaaat tatttgaaga
    12481 ggggattaga ccatttagca gaacagtttc actctacagc tactatttct tttcgctata
    12541 atgacggcta tccagctgta atcaaccata gaggcttata tgcagcactg ttagattcaa
    12601 acaaactaca tgaattagat gctccagttc ttcaagccga agattttggc atatatacgc
    12661 aacaatatcc atgtgtattt ttctttttag gtgtcggtga tacccctgct ttacatgatc
    12721 cgacgttcga ttttgatatg gatgttttag aaaatggtgt agaatggtac aaaacgattc
    12781 tttttacaga aaatcttctt gtaaaaatcg atagcagttc aaaagaggag cgagtaaata
    12841 atgatgaatt tatccaatcg atttagtcct aggctttcta gaatagaagt atcaaaaata
    12901 cgacaattcg atcagcaaat atcgtcgata ccagatgtga tcaaactcac cctgggagaa
    12961 ccggattttc caactcctga acatgtcaag caagcaggaa tagcagcgat tgaagaagac
    13021 ttttctcact ataccggaat gagaggatta gaggaactgc gggaagcggc ttgtatattt
    13081 cagcaacagc gttatggatt aacttatgat ccgcaaacgg aagttttgac gacagttggt
    13141 gcaacggaag cgattgcctc tgcgttgtta tctgttttgg aagaaggaga caaggttctt
    13201 attccagcgc ctgcttattc aggatatcag ccattagtgg aactagctgg tgctgaattg
    13261 atcccgatag atacttctga cacagggttt gtctgtcagc cggaacaatt tgaacgagca
    13321 tttgaacaat atggatcagc tgtcaaagca gtcattttaa actatcctaa caatcctact
    13381 gggacgacat tgtctgcaaa acaattgaaa gcaatcgctg aggttttaaa aaaatatccg
    13441 gtatttgtta taagtgatga agtatatgct gaattgactt atagtggaac gcatatgtcc
    13501 atagctactt atcttccaga acaaacaatc gtgataagcg ggttatccaa gtcacatgcg
    13561 atgactggtt ggcgagtggg ctttattttt gctcaaaaag cccttattga cgaactaatt
    13621 aaagtccatc aatatctggt gactgccgct acaacgatgt cgcaaaaagc tgcggctgaa
    13681 gcgctaataa atggggtgaa agatagcgag aatatgaaag agcaatatca aacacgaaga
    13741 gactatctgg tccagcaatt ggcgccttta ggatttgaag tgacccagcc aaacggtgca
    13801 ttttacttgt tttgcaaact cccagctgcc attcaaactg actcttggca gttttgtgta
    13861 gaattagcgg aacaggcaaa agttgcgtgt atcccaggaa ttgcatttgg cccagaagga
    13921 gaaggttata tccggatttc ttatgctagc agcatggaaa aattacatga ggcctgcaaa
    13981 cggatcaaag actttttaac agaacagtga ttcatagatt ttatcaaaaa aacaatcgtt
    14041 aattttgcgg tatattctgc aaggagacga ttgtttttta aatttagttc aaatgaacgc
    14101 gtttcttttg attcataact aatgtaatgt taagtttaaa ttgtttagaa tgattttaaa
    14161 agaatattca aggaggtttc atcaatggaa aaaatcaaag ttgtcattgt aggtgcatct
    14221 catggagggc atcaatcgat cttggaacta ttgacacgat acggtgaaaa tgtagatatc
    14281 acgctatttg aagcaggaga ctatatttcc ttcatgtcat gtggtatgga gctgtattta
    14341 gaagacaagg taacagatgt aaatgatgta cgtaatttca gaccagaaaa ctttccgcaa
    14401 tccaatgttc atattttaaa taatcacgaa gtaaaaacga tcgatgccga taaaaaaaca
    14461 gtaacggtta ctagcgcatc agataacgaa acaaaagaat atccttatga caaattgatt
    14521 ttgagttctg gtgtcaaacc aaacaatctg ccagtaccag gagcagatct agaaaatgtc
    14581 tacttgatgc gtggatacaa ttgggcaacc aaaatcaaag aaaaattaaa tgatccggct
    14641 attaaaaaaa tcgctgtcgt aggtgcgggt tacattggga tcgaagcagc agaagcaagc
    14701 cgaaaagctg ggaaagaagt cgtattgctt gatgtgatcg atagaccttt aggcacttat
    14761 ttagatgctg agatgacaga tattttagaa caacacctaa atgaaaacgg tattgaagtt
    14821 ttgacaaatg caaaaatcga agcttttact ggtaacggaa aagttgaggc aatcaaaaca
    14881 agtgaaaaag aaatcccagc agatctagtc attcaagctg ccggtgtgaa ggcaaataca
    14941 gaatggttaa aagggatcgt cgacttagat gaacgtggct ggatccaaac aaatgaatac
    15001 ttgcaaacga atcttccaga tgtgtatgca gtaggagatg ctacacttgc ttattctatc
    15061 ccagcacgca aaaaaatgcc gatcgcttta gcgactgttg cacgtagaga agcacgttat
    15121 gtagtaaaac atctttttga agaagtacca aacaaaccgt tcggcggagt cgtaggttcc
    15181 tctgcattaa gtgtctttga ctatcatttt gcagcaagcg gattgaatag ctttacagca
    15241 gcaaaagcag gagtagatgt acgagtgtct tattatgaag atacgttacg accaaaatat
    15301 gtaccagaag aacaaggaaa tccaaaagtg tccatccaat tattctcgga tccaatgacc
    15361 catcaattgc taggaggagc agtattatct acctatgatg ttacaggtca aggaaatgta
    15421 ttggcactag cgatccaaaa caaactgact ttagaagaac tagcagaagc tgacttcttc
    15481 ttccagccag gctttgaccg acaatggagc atgttgaatc tagccgctca acaagcgtta
    15541 ggagaagaac catttgtaga ataagaaaac gaaatatttg aaaagaggtt gtgaaaaagc
    15601 tgccttgcat caagtaataa gaacagccaa gtaaaaacag cttcttatgt ttttaacttg
    15661 gctggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattttcaa aaaagggact
    15721 gtgacacgat ttgtgtaccg acccccaaaa gttagaccaa aaaatctaac ttttggaggt
    15781 cggtattttt tatggttaaa tatacttttg aacttaaatt aaagatcgtt catgattatt
    15841 tggatggcaa aggcgattgg accgtaaaaa tccagatcaa gagattgaag cggaaatgct
    15901 taaaattcgg gagaagcaca aggattatgg ctgtttacgg atgaccaatg aactaagaaa
    15961 ccgcggtttc tctatcaata aaaagaaagt tcagcgcttg atcaagaagc taggaataaa
    16021 agtaacggca tacacgcgta aatcacgtcg ctacaattct tatcgaggaa aagt
//
LOCUS       DAFELK010000063        15889 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFELK010000063
VERSION     DAFELK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.065"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(482..859)
                     /locus_tag="LP433_002360"
     CDS             complement(482..859)
                     /locus_tag="LP433_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006489.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(1159..2040)
                     /gene="galU"
                     /locus_tag="LP433_002361"
     CDS             complement(1159..2040)
                     /gene="galU"
                     /locus_tag="LP433_002361"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL2006490.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(2083..3102)
                     /locus_tag="LP433_002362"
     CDS             complement(2083..3102)
                     /locus_tag="LP433_002362"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL2006491.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(3735..4739)
                     /locus_tag="LP433_002363"
     CDS             complement(3735..4739)
                     /locus_tag="LP433_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2006492.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(4752..5801)
                     /locus_tag="LP433_002364"
     CDS             complement(4752..5801)
                     /locus_tag="LP433_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2006493.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEDFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(5818..6639)
                     /locus_tag="LP433_002365"
     CDS             complement(5818..6639)
                     /locus_tag="LP433_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2006494.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(6626..7405)
                     /locus_tag="LP433_002366"
     CDS             complement(6626..7405)
                     /locus_tag="LP433_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2006495.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(7422..7892)
                     /locus_tag="LP433_002367"
     CDS             complement(7422..7892)
                     /locus_tag="LP433_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2006496.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(7904..8323)
                     /locus_tag="LP433_002368"
     CDS             complement(7904..8323)
                     /locus_tag="LP433_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBL2006497.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(8404..11181)
                     /locus_tag="LP433_002369"
     CDS             complement(8404..11181)
                     /locus_tag="LP433_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2006498.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            11372..11596
                     /locus_tag="LP433_002370"
     CDS             11372..11596
                     /locus_tag="LP433_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006499.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            12375..14090
                     /locus_tag="LP433_002371"
     CDS             12375..14090
                     /locus_tag="LP433_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006500.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            14093..15856
                     /locus_tag="LP433_002372"
     CDS             14093..15856
                     /locus_tag="LP433_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006501.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
BASE COUNT         4666 a         3272 c         2717 g         5234 t
ORIGIN      
        1 gcattgaacg aatacgccca ataccttgac atagcaaata aaacaacgtg cagaccatgg
       61 aaaatatcta cataggggta gaattttcac cctagattag gtacaataaa ttaggtcgat
      121 gcactgcatt gactatggca aaatgatcgg tcagggtgta tgtgtgtgac tggtcattcc
      181 ctgattctta gcgccaacta agggtcaggg agcctttttt tattcagctg tttctatctg
      241 aatttattgt aagtaatctc ttatccaagt gcaagcaaga aaatacaaaa aaacattggt
      301 atgatttata tatatataaa taacataaaa aaaggaatgg cttatcccga tacaacaagc
      361 attcctttaa aaaagattct tttatataag tgaaaaaagc ttttttccac caattaaata
      421 aatctctcat ctcaatagtt tatccattat tttatctttt tttgcgtata cctactaaat
      481 attaccgtct tcttctcgtt cttctacttt gttcgagaga atctgtacta gaaaaagtag
      541 ttgtatgtct accttttctg cctatccgag actttctttt catatatggg atataaatga
      601 ttagatacag tacagcaaaa aataaagcaa atacgcaagc ttcccaacta cctaacgcca
      661 attcaaccat caaggtagca accccaacgg atgctgcata ccagataaaa atcagaaacg
      721 tttctttttt tctgaccatg cgaaacatga taaatagact aataagcaat agtggcaaca
      781 caaatatcca attgcttcct tccatcagcc acttgagtat atcaagcagc gactgtgcaa
      841 cagcgactaa ttttcccata gtgaacacac accttttttt ataattaaaa aattcgcctt
      901 tttattctac tatgaatctt ctggcttggc tttcatttct cttatgtaat cattttcttt
      961 tatacaactt aaaaaaaaat taaaccatta gcataatatt ttctgaatct attcacgaaa
     1021 gtctttttct atctttcgtt ttccacgact caactgatct agagtcaaaa aactaaaacg
     1081 acagttgcgc aaatgacgca caagctgccg ctttaataac aaatagcctt tcattctcag
     1141 caggccactt atttccagtt aactttctgt tcttagcttt ttactcaact ggataatata
     1201 tgcacttaat gaagtcccaa tttccgaatg ttgaagtcca tattcaatat ttgtcttcat
     1261 atatcctaac ttatcgccta cgtcgtatct ttttccttta aactctctcg catagaccgc
     1321 ctctgtctgg ttaagagtct gaagtgcatc cgttagctgt atctcgtttc ctgctcctgg
     1381 ttcttgagtt tctaatatct caaatatttt aggagtcagt agataacgtc cgataatggc
     1441 taaattactt ggtgcttttc ccatttcagg tttttctaca aaccctttta ctctgcaacg
     1501 acccttttcg ctatctgttt taggatcaat aattccgtat ttagatgttt cattttctgg
     1561 tacacgcatg acggcaacag cggaagcttg tgtttcttca taatccatca tcaattgttg
     1621 agtcaatggg atatcatctt tcatcaaatc atcccccagc atgacgacaa acggttcatt
     1681 tcctataaat gcttttgctt gaagcacggc atcccccagt cctcttggat gagattgacg
     1741 gatgaagtga agattgactt gagtcgtttc ttcaactaaa gcgagtaatt ctgttttttc
     1801 cttttcccgc aaattgtttt ccaattcgat atttgcatca aagtgatctt caatgggtct
     1861 tttttctttt cccgttacga tcaagatgtc ttcgattccc gaatccaatg cttcttccac
     1921 aataaactgg atcgttggtt tatccacgat tggaagcatt tcttttgcca tggcttttgt
     1981 tgccggcaaa aaacgtgttc ctagcccagc ggcaggaatg actgcttttt tgaccttcac
     2041 ttgctgttcc tcctaaacga cgattaacta ttgatcatct atttaacgaa gagaaaattc
     2101 attctccatt tttccgtcac gtaacatgat ttcttttgct gcttttttga tatcttctcc
     2161 attatacaaa acattataga ttgtttgagt aattggcatc tcaacaccta gctgttgagc
     2221 tagctctact gctgcttttg tcgttgccac accctcaacg accattccca tgttttctag
     2281 aacttcttcc agcttatgtc cctgtcctaa caagttaccg gcacgccaat tgcgagaatg
     2341 aacacttgta caagtaacga tcaagtcccc cacaccactc aaaccgataa atgtcagagg
     2401 attggcaccc atcgcgacac caagacggct gatttctgcc aatcctcgag tcatgattgc
     2461 tgcttttgca tcatctccga atcctaatcc atggatagcg ccggcaccaa ttgcaatgat
     2521 atttttcagt gctgcaccag tttctacgcc aatcacatca ttatttgtat aaatcctgaa
     2581 ataatcattc atgaacagtt tttgtacata ggctgctgct ttttgatcaa tacttgcagc
     2641 tgtaattgtt gtgatatcat gtactgccac ttcctcagca tggctaggac cagataatac
     2701 aacaattgcc tgtctttttt cttctggaat ttcttcagcc aaaacttctg agattcgttt
     2761 atgcgtatct tgttctagtc ctttacttgc atgtataatg attggcttag tattcatttt
     2821 accaataagt tcctgtgcga ctgaacgaat cgcttttgtt ggaacaacaa ataaaatagc
     2881 atctgcgtta tccactgctt ctgccaattc tttatatccg ataatcgatt ctgggatcgt
     2941 caaatcaggt aaaaaatgct gatttgtatg atacttattg atttcatcaa tctgttcagg
     3001 tacatttccc caaatacgga catcatgccc gttttctgcc aatgtttgtg ctaaagcagt
     3061 gccccaagat ccaggaccaa gaactgcgat tttttgtttc atggatattc ctccaaataa
     3121 ataattgata atttccatta tagtatacat ttcttaaagt tgggactaat ttccattgtt
     3181 tttaagtgtt tgtttacttc ttttatcgtt tttacttgaa ataatcaatg atatgttaca
     3241 atagtctaca ttttattttt acactcgtta tgctttgctt gttcctaaga ggaagcagtt
     3301 ttgacaatgt tactaccagc attactatta ggaggttagg aaacttctcc tagtgagtat
     3361 tgatttaaaa tacataagag acagattgaa catttctaaa tctgtcaggt cctgcaacgg
     3421 acagattgtc tctgttgacg gttgacatag gaacttttgt tttagtcaac attctggata
     3481 caaaacgcta tgtaaactgg cgcaactcgt tgtacttgga cttttactac ggatccatgc
     3541 aacaactaaa tagtactatt gcataacaaa aaatggttgg cacccacatg tcccattaaa
     3601 cagattataa gttgaactgt agataatgca aaaaatgtgt tttataacgt aattgatgcc
     3661 aatattttaa aaaaataaag ggagcagtta tcgctgctct ctttattttt tatattcttt
     3721 ttatccagtc tatcctaata atcaaactga cgatagtagc ggcgtatctc taatggatgg
     3781 cagttcaact gctccacatg agcatcgatg cgttgtgtca ctacatgcat caataagaaa
     3841 gacaaaacac gtccgcgata tttttcactg ataccttcta ctggatagtc ttttgtgtct
     3901 atcaatgtat aattgctgca aatttttggc aaaagtttag ccacacgttc agataacact
     3961 ctctgttcat cttcgcctaa aaataatgtg actggggttg tttcttctac gatctctaac
     4021 gtcccgtgaa gaaactcggc agcatggata gatttcgatg gaagccagct ttgttcttcc
     4081 cagtaacaca tggcatatga ataaacagct ccccattgat tccctgctcc aataaaataa
     4141 tgcatactat cacgtcgatg tttttctgca aatgataagc caaatgcatc tgcttttttc
     4201 tctgcttcca ctaaccctgt tggtaaataa cgttcgagct gttcatagta ttctgaataa
     4261 gcttcgaatt ctccattcaa atacatcaat cgatctgctg ccataaaaaa tttgatttgt
     4321 tctgttccag gagctggata agtgaccaca aaatcgcata gctgagacaa cttactgttc
     4381 gctttatcga taaatccaat cagtgtcgct cctactttct tgatttgttc tactgctttc
     4441 actacttctt gagttgtacc ggtaacagag gacaaaataa cgatagaatc ttttgttaat
     4501 cttttgtttc cagtagtgta atattctgca gcatgctgta caaagacagg caagttgctt
     4561 ttcccattca tataagtgac agcttgcatc gaggaagcat acgttccacc gattcctaga
     4621 taatagacag cgtcaaattt ttccgcataa agtttatcga tgatttcttc tacttgcgga
     4681 cgtaaagcta gtgcgccttt tattgctttg atttgttctt cttcattgaa tttcagcatg
     4741 atttccacct cttataattt acttttcaag actgtatcaa agtcttcaaa aatctttttg
     4801 ttcaagtcaa tacctttagc tactgcggtt ttataagcga atagttgaaa cggaacgaca
     4861 agcgctaata cagacagata ttcatcacat tctattgcta atccaagtgt tttctcgttt
     4921 cttgcttttt ttgtggtaat ggtgagagtc tctccaacgt accgactcat atatctttgc
     4981 aacttttgcg aacgttcctt atttacactt tccccttcaa taaagaatag caaatgcgaa
     5041 gcatctgcct ccaggtatgg gccgtgcata taagcttcta actcaaatcc ttgtgacgga
     5101 acgcggattg tttcagtcaa tttcgtctct gcttctttag ctgttcccca gtttggacca
     5161 tatccaatgg tgacgaaacg ctgtgctaaa cgaaataaac tttgatatcc atcaaaaaaa
     5221 tcttccgttt tttgaataat cgctggtaaa tggttgatta ttttgcgcaa ctgttgcatg
     5281 tagtcttgtt ctattttttt gctgatttta tttttactta ttccaattcc tatccctaag
     5341 agtagtaact gtaaaacagt cgcagaatag ccttttgtaa cgaagcctac tgattctacc
     5401 ccggcaccta aatcaataat ttgtgcagct tctaaagcaa gtggactttg cacgtcattt
     5461 gtgatagcaa caacaggtaa cccttgtttt tgtatcattt ttactgcttc aacagtagaa
     5521 gcacttttcc cgctttgtga cacagcaatc acagtatcga ttgaaggaga aagttttcca
     5581 taattgaaaa aataaaaagg ttcttgaata tcgacagtaa gatcaccata agattccaat
     5641 gctggcttcg ctgctaaaca agcgttataa gatgaacccg ttgctaagat cagtaaattc
     5701 actgtttttt tcatatgttc tcttgtcgaa aaatcattct ttttcaagat cgtacttagt
     5761 acttcctttt cttcatagat ataatcttgc atcgtaaaca ttttctctgc tcctttttta
     5821 aaaaatccct atccacgaac caaaaattcc aaagaaagct agtccgatca agatcgttaa
     5881 tggtttcact tctttcttca atagataaaa cactatgcca aatgctccaa gacataagat
     5941 atttggaacg atatcatcaa aaatactttg aacagtcaca gcattttctc ctgaaccgat
     6001 ttttaaagga atattgatgg tgatcatcgt ggcagtcatt gctccaacga ccatcagtcc
     6061 aataatagac gcgcctaatg tcaaactttc catcataccg tttgcctgga tctttttcaa
     6121 aaaacccgtt cctaagcgat atccccaacc tgttgctaga tagcgaaaca gaatgtgcgg
     6181 aatattgaaa atcaaaatga acaagatagg gcctaaaata tttccttgca tggctaaaga
     6241 ggtacccaca cctgtggcaa tcaatcgcaa agttccccaa aagaaagaat ctcctaaccc
     6301 tgcaagaggt cccatcaaag atgttttgat actatcgatc gcagtcacat caaattcagg
     6361 atcatcctta ttttcttcct ccattgcagc cgtgattcct aaaatcagtg taacgatatg
     6421 tggggtcgtg ttaaaaaact ctagatgccg tttcaaagct gctgccattt cttctttcga
     6481 ctgatataac tttttcaaaa tcggaatcat tgcataaaca taagccatat tcatctgacg
     6541 ttcataattc caagaaaact ccatttgaaa agaacgccaa aatacgtgat ttagctcttt
     6601 tttcgttatt ttgctgtttt tgatctcaga attcttcatc ttcttctacc tcccctgcag
     6661 ttgtttgaag tggtagttga cggacattca taatattgac taccacaact gctaaaatcg
     6721 caccaaaaat agctactccg gtcacaggaa tctctaagta agaagctata gcaaaaccta
     6781 agaaaaaata tggtgcaact tgtttgttga tcagcaaacg agcaagcatc gcaaaaccaa
     6841 gagctggaat caaccctgta gctactgaca accccttttg aacgaagtca ggaatcatat
     6901 ttaatagatt tccgatcgta ttgcttccca ccatataaga aaccattacc acaacaccaa
     6961 gcatcaagga aagaccgata ccggcaagca agtgcatatg ctcgactcct ttataatttc
     7021 cttcttctgc ataattgtct gctttatggt tcataattgg aatcaaaagc cctaagtaaa
     7081 tatttttcaa tatcaatgtc aacgtagcaa tcggcaaacc tagtaaaagc gcggtttctg
     7141 taccggctcc agctgtaata gcaaaagccg tccctaaaat cccaccggtc acaacatcag
     7201 gtggaatcga agcacctact gagaacgatc cgataaatgc taactctaaa gttgcgccca
     7261 taatgatccc agtttttaca tcacctaaca cgattcctgt aaacagcccc gtcacaatcg
     7321 gacgagaaag caacgatgtc cctagtgcat attctgattg tgcgacaaat gcaacaattc
     7381 ctaataagac tgcttgtaca atcattgagg ttcttccttt cttacaaaac ttctcttaca
     7441 tccacttttt tatctgctgg tacttgacgg atttctactt ctatttgttt gtcaattaat
     7501 cgtttcaagc gttcctcctc ttctggtaaa atatttaccg cttttccgat gctgcgagta
     7561 ccaggttttg ccttgatccc tcctaagttg atggttttga tttctggata cgcttctgcc
     7621 agcttatatg catcctcgat cgattccact acgatgaata acttatattt atctgtcacc
     7681 ccgcttttca acgcggcaat cgagtcatca attgatttga tcactagttt gactccttgt
     7741 ggcttggcta atttgatcgt tgtctttcgt atctcattcg taggtacatc atcattagca
     7801 atcaaaatac agtctgcgcc tattgtttgt gtccatgaaa aagctacttg tccgtgtaat
     7861 aaccgatggt cgactcttgt caatacaatc atttttcttc ctcctaaaat tcgtcttctt
     7921 ctattttctg attgagccgc tcgttacaaa actggatcat tttttttgaa tcagttagca
     7981 cctgctggat caaaacagtt gtctctactt cagcgtccaa ccgagatact agctcaatca
     8041 atagtggcaa attcaatccg gcaacgagat agacatgatc ccgattgata tattgtaaga
     8101 attcgttgtt gacacttccg ccaaaaagat ccgtcagaac aatgatttct ttatctttgt
     8161 acctcataaa aagctgcctt actgtttccg ctaaatcaaa attctcatca gtatagcaat
     8221 cgaatacagt aatagaatga tttttcccat agatcagctc taatgaatct aatatccctg
     8281 aagcaaattt tccatgggaa gctaagataa tttctctatc cactttttca tctcctcttt
     8341 tcacttacac atactaaaaa agcaagttgc atgccaaaat tagtggcaac aacttgctta
     8401 tgttcaaaat tcttcttcta tcgagagaaa ctctgtatct tcactcaaaa tatcatagat
     8461 ataggcaatc tcagaattgg ggatcatgac actataatgc tcttcaatga cactaaacgc
     8521 agatttaata gcagataacc cttctttttg acactgcttc catttctcta atccttgata
     8581 ggtttcgatt ggcatttgtc ggatcaatcg ttcaatgaga cagctcacat ggacatacaa
     8641 cgctaatttt ttgggattgc tgatgcttcg attcaactgc acctctaatt ctctcataaa
     8701 atgatcgatt tctcccatca ccttctctgt atctagaata gtcacggaat ccagtacttt
     8761 ttccaatgaa aaattacgaa tgatgcgctg attgaatatt tccttctctg aagcattcat
     8821 agtagtgtcc aaccattcag ctagtacaga catcttttcc cccgagatga ggtcttctaa
     8881 tgaaagatag tcgatattgg tgatatcagg atctgtggtg ccaatcattc ctacgacttc
     8941 gtatatggaa aataatgggt cactgttttt cttatctttt aattgctgat attcatatgg
     9001 gatgattttc aactgacaag ccgtaggtaa gcttttttct agcagttcac ttaagtggac
     9061 cgccgtaccg attccagtga agcaagtagt aatgagtgct ttgggtttgt tttcctctgg
     9121 atagagcagt cgccattctg gctggatctg tcgaacagtc tcttctgcta tctcttctaa
     9181 tgatacattt ttttgcaggc attcccctac tgtgattgct aaaggtgtcg tcacattatt
     9241 caaaatcaaa agcggtacgg ataactgttt tttaaaaaac tgatggattt ctttcagaga
     9301 tcccatgtct actaatatga tcaatccatt tgaaacatcg ctgttttcgc aataatcaag
     9361 gatttctgaa gcaatctgct gtggtgtgac atctagtggc atatcaaatg attcaaatag
     9421 atcctcttgt aataaacgat ttactacatt tgccatactg ctagcagttg cataaccgtg
     9481 agcagcaatc atcgcttttg gcagtcgttt ttcttttgac catttcgctt tttttagata
     9541 gatcgtcagt aaaatccgat ccatacttgt gtcttcaata tctaatttga tcttacttaa
     9601 ttccagaatt cgttggacat agtgataact agatggataa gactgagaaa cttgttgttc
     9661 taattctttg attagttgga taatatcatg ttcttccggt aaccatttga tagtgcttcg
     9721 ctgatagaga tagtaactca aggcatagac actgtttcca tcgaatttga tttgataggc
     9781 agtttccatt tgtcgaaagg tctctcggat agattgtgtc caataaacca gcagctcgtg
     9841 tttttcttgt ctactggtct caaacagcaa aaaatcaaat aattgaatca cttcttgctt
     9901 taattttcct tcgcaagaat atagcagaca gttatttttc ttgaaatcaa ttaggatttg
     9961 ctcaaaactt ttaacgattc gctgctgttc gggctgttgc ttctccatta attgctctaa
    10021 ggtctggtct tgcgtaatat agattccttg ctgtgctgta tttttagtaa taggctgcgc
    10081 aagtagttct ttttgcaaat gatggatcgt gacatggatt tcaggctgtt cacgctgttc
    10141 agcatatgct tttgctgctg aaactttgac gatatttttc agctctccta tgtttccgga
    10201 taatttctga cttgttaaaa gtgacaaagc tggtccactg actgacaaag ggctccccat
    10261 ttttctttgt tcttcgagaa aaaaagagta aatcagttct agccgttcat tacgactacg
    10321 ctgattaagt gcaggtagtt cgattcggat aggtattctt cgaatgaaag ttgttaagaa
    10381 atgactagta atctcttcag tcgtagcaaa aaagagacgt gttttgatcc ggcgtgacaa
    10441 attaggttct cccatacgat aaatcacacc ttgatcaaga taggtgaaca gtttttcctg
    10501 accttctggt gttaagcgat gtacctcgtc taaaaacaag atcccaccat ctgctgcttc
    10561 aaaagcccct tttttatttt cttctgcacc agtgtacgct cccttaacat gtccaaacaa
    10621 attgctagtc aaaagttcag gattatctgc atattgtgca caattaaaag tgatgaatgg
    10681 tgcagaatct tctagcagat catgaagcag acaatactga tagaccaaat taactaaata
    10741 acttttacct gtgccacttt cgcctgtaat caaaagtggt aatccgccat ctggatagta
    10801 aagagctgtt ttgatttgtt cgatactttc tttcaaactg gcgtcgtatc cgatcataaa
    10861 agagaataag tcttttggtt gcgcgaaaaa aggctgttcc tctttgagat catcgataga
    10921 aaaataaaaa ttcgtgcgta acttaaaaaa ttgtttttca aaagcttctt tgtggaaata
    10981 aatcactggt cgagaattga ttttgactag tagttgctca tcatttaact ggttcaaata
    11041 atgactgact gtgtttcttt ttaccccaaa atgatcagct aacctttgtg ctgtaaagac
    11101 ctcgttcata tgttctaaat cgaaaaaggc tgtctggttc tctaagtaac ataaaatttc
    11161 cttcttcaac aacttattca cccctcctcc atcatagaaa acggattcat tttgtcaata
    11221 aaatctttaa taaagaattg aaaaatatat cttattatag acagcagcct acttatccct
    11281 tataattttt attctaaaaa acgtacagtt ccttccagtt tttatactgg aatttcaaca
    11341 tatgaaagaa taaggaggct atgactattc aatgaaatcg gataaatata aaaacaggaa
    11401 acatacttcc tggaaaactt ttcgagaaat catcggatct tatctcgctg tagttgtatt
    11461 tttgcctttg ctttatatgg ctatgacaga acaaactcgt tttattggcg tagatacgca
    11521 atatatagcc gaaacaggat ttttattcat ctttatcttg atttttgcgt tctataaatc
    11581 cttccataca aaataagatt cacagatttc aactttcctg tctgttttta gctattacaa
    11641 atccttatat gtggtataac aacaatttat tggcataatg aggaaaaacg agttatgatg
    11701 ctttcagaga gtaaagaggt actgttgtca ccatcctttt tattgattac gtacaccact
    11761 cttagttttt tcccattgat tacgaaaaca aggtagaaac attgatgttc ctaccttgtt
    11821 ttcttttttt attttcagat caaaatctca agtagctttt gacttgatgt cgggaggttg
    11881 tcttcgttcc atcaaacctg atagaatctg cgccaaacca tagttttctc cactattatt
    11941 tattcctcta agatagtacc cacaataaac gaataaatat ttttctcatt ttcatactcc
    12001 ttctttgaaa atcaattaga tttctctcaa cccacttttt tacaaaaatt acgtagcaaa
    12061 aaagattgca agaacaaatt aaaaaagaag taaatagagt ttcatctata aacatttact
    12121 tgatatattt tttatgcaga attcatttat agaaaaatta agtaaaatag acgttcctat
    12181 gaatgaagag actggcatgt tttctcattt tctttttttt aaaaaaaata gtctattcaa
    12241 tttctaaagc ttcttcataa taaaactttc atttatgaaa aggcttgttc tcttttcatt
    12301 ctaaatttcc taagctacaa tgtggtagta cttgtttttt caattgtgga caaataaata
    12361 ataggaggaa tcatatgatt cagttattac gttatgcaaa agactatcgt aagcaaatca
    12421 ttttgggccc gttcttcaaa tttcttgaag ctgtcttcga acttgtcctg cctttaatga
    12481 tggcttcctt gatcgataat ggactaaaaa tgaatgaccg aggaaaaatc attgaaatgg
    12541 gcttatggat ggtcgctatg tctgtgattg gtctgatttg tgctatcatt tgccaatact
    12601 atgcttcagt agcttcacaa ggatttggta cagagttacg taatcagcta atcaaaaaaa
    12661 tcaatacttt ctctcacaac gagttgaatc attttggaac agataccttg atcacccgaa
    12721 tgacaaacga catcaatcag cttcagctag ctttagcaat ggtcattcgt ttattgatca
    12781 gagcaccgtt tttaagtatc gggtcagtgg tcatggcttt tgtgatcgac tgggaagtag
    12841 gtctgttttt cttagcatta ttgcctattt tctcaatcat tttatttttt atcatcaaaa
    12901 aaaccgttcc tctctaccaa aaagtgcaag aaaaactaga tcagctcaat gaacacgtta
    12961 gtcagaatct tagcggtgtt cgtgtcatcc gcgcatttgc gcagacaaaa aaagaaacag
    13021 agaagttcga taaaagcaca aatgatctag cgaacaatta tttacgtgtt tccaatatct
    13081 ctgccctatt atcacctgct acaaccttga tcatgaatgt cgggatcatc tgtttgctga
    13141 cagttggcgg gatcaaagta aatattggta gcttgcaaca aggacaagtt cttgctttga
    13201 tcaattatat gaatcaaatg cttttggcac tgatcgttgt ttcaaacctc gtcgtgatct
    13261 tcacacgtgc cgaagcttca ggaaatcggg tgaaagaggt gctagacaca gaaaattcga
    13321 ttcttgaagc tgaggtcagt actactcccg atttttcttc tgaagcaatt atcgcttttg
    13381 accatgttga cttccgttat actcctgatt ctggtctttc tctccaaaat attacatttc
    13441 agctgaagcg aaatacagtc cttggaatca ttggtccaac cggaagcggg aaaacgactt
    13501 tgacacaatt gattccgcgt ttctatgatg tcagttccgg tacagttata atggacggaa
    13561 tggatgttcg ttcttggcag ctggatcatc tccgtcagca aattgctctt gttccccaaa
    13621 cttctgtact atttaccggg actattcgtg aaaaccttca atggggtaag aaagacgcca
    13681 cagaaaaaga atgttgggaa gctctgaaaa tcgctcaggc agaagaattt gtccgtcagc
    13741 ttccaaatgg tttagataca aaagtcatgg aaaatgggaa aaatttctct ggcggacaaa
    13801 aacagcgact gacgattgca agagctttga ttgccaagcc agcattactg attttagatg
    13861 actctttaag tgcgttggat tatcaaacag acttggattt gcgtaaggcg ctacagactt
    13921 atcttggcag tacagtgatt attatctccc aacgtgtccg ctctattcaa gaagcacatc
    13981 atatcttagt gatggatcaa ggtaagattg ctgctcaggg tacccatgaa gaattacttg
    14041 ctcaatcagc agaatatcag gaaatcgtcg catcacagga ggaagaatag ttatgaaagt
    14101 aaaaaaatta tccttgcaga cgctccgccg attcattcct taccttactg cctatgcaaa
    14161 agacatttgg ctagctgtga tactaggaat catcaatggg attgcaacag ttgtgatgac
    14221 gttacaaatt ggtcaaagta tcgatcaaat gattggagaa ggacaggtcc gcttcaatcg
    14281 actgttccat ttacttattc tattcggtgg tatcgtttta atcaacgtag tcagtcaatg
    14341 gctcatccaa gtgttaagca atcggttagc ttacttatcc gttgcaaaat taagaaaaga
    14401 tgcatttgct catctgaatc gattgccact tcgttattat gatcaaaact cccacggaaa
    14461 tatcgtcagt cgatttacaa atgatatgga caatatttcc attgcaattt ctgcggcctt
    14521 caatcaatta ttttctggag tggcaatcat cattctttcg tttattttta tgatgcgtct
    14581 aagtccactt ctgacattgg tcgttctttg ttctacacca attattttcc ttgtgagttg
    14641 gatcgttgct cgtgcttcac aaacaaattt cgatagacag caaaggatta ttggggatat
    14701 ctcgggcttt gtgaccgaac gaatcggtaa ccagaaaatc gtgaaagctt ttcagcaaga
    14761 agaagctagt caacagcaat ttgaactgct aaatgctgat ctatatgaaa aaggacaacg
    14821 ggcacaattt tcttcttcct tgacaaaccc gtcttctcgt tttgtagatc accttgctta
    14881 tttatcgatt ggtttagttg gcggcctatt ggcattgaag agtggttcgt caatcactgt
    14941 tggtgtgatt tccagcttta cgatctactc aagtcagttt tctaaaccat ttatcgaact
    15001 ttctggaatc acgacacaac tgcaaaccgc tttttctggt ctagaacgag catttgattt
    15061 gatcgatcag ccagaagaaa agcctgattt gccagatgcc tatgccttgg aacccaaaaa
    15121 tatcaaagga aaagtctctt ttgatcatgt ttctttttct tatgacccca agcagcgttt
    15181 gatcgaagat ttcaatttta ctgcttatcc aggtcaaacc attgctatag taggaaaaac
    15241 aggggccgga aaatccacac ttgttaattt gctgatgcgt ttttatgaca caacaaaagg
    15301 aacaattaca gtcgatgacc atgacatccg ctctatccaa cgtgatacat tacgtaaaag
    15361 ttttggaatg gtgttacaag atacttggct atttgacagt acattgcgag aaaatcttcg
    15421 ttttgggaat ccggaagcaa gtgacgcaga aatcaatgat gccctaaaag cctcttatat
    15481 gtatgaattt gtagaacgtt tgccggaaaa attagatact aagattggcg gtcaagggtt
    15541 aaagatatca gatggacaac gccaactgtt gacgattgct cgaacgatga tcagtaatcc
    15601 ccctatgttg atcttagatg aagctaccag ctcagtcgat acattgacag agaaaaaaat
    15661 ccaacaagcc ttcttagcaa tgatggaagg aaaaaccagt tttgtgattg cccatcgcct
    15721 gtccacaatc aaaaatgcgg accagatatt agtgatggat cagggagcta ttgtcgaaat
    15781 gggcacccat gatgagctgc ttcaaaaaga tggttattac cgacggctct atcaagcaca
    15841 attcacagca caataaaaac aagcagtctt ctgggatggg aagactgct
//
LOCUS       DAFELK010000064        15698 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFELK010000064
VERSION     DAFELK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.066"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..1085
                     /locus_tag="LP433_002373"
     CDS             <1..1085
                     /locus_tag="LP433_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2006502.1"
                     /translation="INDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1303..2445)
                     /locus_tag="LP433_002374"
     CDS             complement(1303..2445)
                     /locus_tag="LP433_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2006503.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2450..2635)
                     /locus_tag="LP433_002375"
     CDS             complement(2450..2635)
                     /locus_tag="LP433_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBL2006504.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2989..3234)
                     /locus_tag="LP433_002376"
     CDS             complement(2989..3234)
                     /locus_tag="LP433_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2006505.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3228..3629)
                     /locus_tag="LP433_002377"
     CDS             complement(3228..3629)
                     /locus_tag="LP433_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2006506.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3816..5624)
                     /gene="uidA"
                     /locus_tag="LP433_002378"
     CDS             complement(3816..5624)
                     /gene="uidA"
                     /locus_tag="LP433_002378"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBL2006507.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5647..7413)
                     /locus_tag="LP433_002379"
     CDS             complement(5647..7413)
                     /locus_tag="LP433_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBL2006508.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7426..8220)
                     /locus_tag="LP433_002380"
     CDS             complement(7426..8220)
                     /locus_tag="LP433_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL2006509.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8230..9606)
                     /locus_tag="LP433_002381"
     CDS             complement(8230..9606)
                     /locus_tag="LP433_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2006510.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9726..10373)
                     /locus_tag="LP433_002382"
     CDS             complement(9726..10373)
                     /locus_tag="LP433_002382"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBL2006511.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10457..11884)
                     /gene="uxaC"
                     /locus_tag="LP433_002383"
     CDS             complement(10457..11884)
                     /gene="uxaC"
                     /locus_tag="LP433_002383"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBL2006512.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11958..13037)
                     /gene="uxuA"
                     /locus_tag="LP433_002384"
     CDS             complement(11958..13037)
                     /gene="uxuA"
                     /locus_tag="LP433_002384"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL2006513.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13040..14671)
                     /locus_tag="LP433_002385"
     CDS             complement(13040..14671)
                     /locus_tag="LP433_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL2006514.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14975..15646
                     /locus_tag="LP433_002386"
     CDS             14975..15646
                     /locus_tag="LP433_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2006515.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
BASE COUNT         5088 a         3064 c         2117 g         5429 t
ORIGIN      
        1 atatcaatga tgatggctca agaaaaaaag tggagaaagt tggcggagac acccgaccag
       61 aggccgaagc tgctttacga aaagttttat cagatattga cgaaacagga caatactttt
      121 taggtacgga tactcgagta aaacaatacc ttgatttttg gatggaggaa tacgttaaac
      181 taaatctaaa atacaatacc tatgaaaact accgatttac catcaaaaat catataaacg
      241 gttatttagg aaagaaaaaa cttacggatc tctcccctgc tcttttacaa aatttcatca
      301 atgctgaatt taaaaagggt tactcgaaga aaacaatgac tattactcac tctgtcctta
      361 agaatgcgct gaatatggcg gtttatcctt ggggattaat caagcaaaat cctatgctgt
      421 atgtaaaaat accaaaatat gaagcacgac caacgactaa aaaagatcta aaaatcattt
      481 ctcttgagga ctttgatcat atgctagaaa ttactcctga aggacatcct ttctatattc
      541 ctttgaatat tggattttat acgggaatgc gcgttggcga agtttgtggt ctgacgtggg
      601 atgatgtcga tttttcaaat ggaacaatta ctgtagagaa acaaatggta aagaatgacg
      661 gcgcatgggt atatggtacg ccaaagacaa gcagttccaa tcgaacgatt tttattggac
      721 aaaccttgct agcaattctg aaaaaacata agaaacaaca attagaaaat cgaatgaagt
      781 atggaaagct ctacattgat tcaaatgcag tatgtacgaa ggaagacggt gagctagtta
      841 cgccaagtgt agtgaaatgg aatactagga ggatatcgaa tgcactctcc ctctctttta
      901 acttccattc tctcagacat actcatgcta cacttcttct cgaaaatggc gcaaaaatga
      961 aagaaatctc tgaacgattg ggccacagca gaatttcaat tacgatggat acttactcgc
     1021 atgtaacaga taagatgaga aatgaaacgg tcgatatcat ggaaaatctt agaaagaatt
     1081 cttgattttt gccaccgaaa aaaaccaccg gtggcaaacc ggtggcaaat ccatgtaaac
     1141 atggtttatt ttttacactg ttttcaaaca aacccttgct atttcttcgg ttcgtcctcg
     1201 tccattttcg ataccgacag ctagcttata acccaaggta tatcaacata aaaaaataaa
     1261 aataggctat gacagcagcg tgacagcaaa aaagatggaa agttaaatat caaacctcgt
     1321 aatttcattt gcgagtgctt gatttgtttc tggatataag tgtccatatt tgtccaaagt
     1381 agttttaata gaggcatgac ctagacgctt agatattgca tagatatttt tattatgttc
     1441 aattaaaaag gcaacatgcg agtgtcttaa tccatgcata tgaattggtt ttactcctgc
     1501 aatttcagct agttttttta ttctgcttaa aatagttctt ggagatggcg gtaatccatc
     1561 aaaagaaaaa accaattcta tatttttccc aattgattgt tgagtttttt tccatgtttt
     1621 taaatcttca acggtttgtc tgtctaacga aattatccga atacttgatg tattttttgt
     1681 ttcagcaaat tcataatctt gtcttgtacg gatgtaaatt gacttattta cgctacatct
     1741 gccatttatt aagtcaaagt ctttccattg taacgctaag agctcctcac tccttacacc
     1801 tgtaacaaaa ataaaacgca tcaaacgttt ataaaattct tcataaaaat ccccgtgata
     1861 aacactatta tatactttct taaattcatc aactgtccaa aattctactt gaggacgctg
     1921 agtttttatt ttacctatag tatctacagg attttcttca ataatttcaa gtacaattgc
     1981 ccttttaaaa actactctca acttattgaa tatctgttta atataatttg gtgataatgg
     2041 ttgctcaatg ccctttttta caacatggat tttcgataaa aactgttgaa attcctgtat
     2101 atgaattggt cgaatcttta caacctgcat ttctccaaaa aaatccaatg cacgttgtaa
     2161 aatatgatct gttttcatat atgttttttc tacagttccc aacttatacc aaggaaaaaa
     2221 atactctcga taaaaatcat gaaacgttat tccttgcaga taaattcctt gtgaatcaga
     2281 aaaactttgt tttaactctt cgagtcccct tctagcttct ccttgagttt tgaagcctct
     2341 tctggtcact tgaattcttt ttccaaagcg atcttgtcct aaagttgcag aaaaaaacca
     2401 agtgcctctt tttctgtctt tataaacatt cgcaattttc ctcattttac tattcctccc
     2461 aagaaatatg gagaacttct tctaaaattg aaataggaat tctttttatt tttgaattac
     2521 gataaaaaaa gtatcctttc tcaactaaaa gttctttaca ttccttgaag attttattag
     2581 catagtactg agaaaaacct agattaatca aatcttttcg agtagctgtt ttcattatag
     2641 caccttcctt actttttttc atttatttct atcagctgct tttgtcaaaa gcacatagga
     2701 atttcacctc tccccaagtt tacggcgagc cttacggaag tatcattatc ccaactttaa
     2761 atcatcgctt tttattgact ataaaaatta ttttagaata tttatcgctc cttctttaca
     2821 gcaagaaatc atggcgcaac taaaatatgc tccttaaagt gttaacgtac tgatagaatc
     2881 tatttaattt tcaatgaaca ataggttttc tacctaaaag aatctactaa ttccttaact
     2941 attagaagat tcttttaaac agaaaaagtg gaaaggggat ttttttaatt agttaatttt
     3001 aaattttaag atcgcttcta ttaatttaat ttctagctga cttatcatat attcatctac
     3061 ataggtaacg aattgaccta cctcgttaaa tccatttgtc aaacataact tagccatata
     3121 agaatgataa tgtttgagta tcatcttgat cgaaattgga tctccttcta gagcagataa
     3181 gataatggat agtggaacta ataggtactg ccgcttttta gatttatcta ccataggtca
     3241 taccccattt tcaattgttc aactgccttc tttcgttgat accagatacc acttgtgctc
     3301 atattgagaa ttttaccgat ttcagcatca ttaaaacctg caaaataata aagtaggata
     3361 atctttcttc ttatctccga taactgatca attgctgctg ataacttttg atctgaaatt
     3421 aatatttcca ttccaaataa gaaatagaca tcttgttcat caaaatgagt ttgggaatac
     3481 ctgccttcat ttgaatctgc caatggttcc tcattatcct ttatgttagc gtttcgtttt
     3541 cgaatagact tagcttcgtt tcgtaatact tttttacagt aggcatcaaa ttggtgttgt
     3601 atagatatgt cattgtaatg ttgttgcatg ataatatgct cctttttccc cctttccact
     3661 aatacaacaa tcagaaagcc cctttttttc gaaaaaacta gaaaaaaaac ataaaaatat
     3721 ttatcattct ttaaacagaa aatctttcta taaaaaacaa aaaaaaacga ttaggctagg
     3781 ctaatcgttt tttgaacatt cttaaaaaat ccaaattatt ttttataact gaaattgggt
     3841 attgatgacc atcgtttctg tagatagtaa gcaatcattt taggttttct atctctagta
     3901 aagattcctt tcttatttcc ttgcactctt aaaatccctt gacttgttgc aaaatctgca
     3961 aaattccaca cttgttcacc aacaaaattt tcacatgtat ctattacttc gtgatttgct
     4021 tcgtaataag ccacttgata ctcttctgta aacattgttg gtactgtatc atgaaatcca
     4081 gctactgtat ctgctccata ttctgtaaac attattggcg tatcaggaca tctttccatc
     4141 catccatcta gctctttttt caacagatat tttgcatgtg ccagatcccc tcccgaaaca
     4201 taccaaccat aataacgatt taaacataaa acatcgacaa tatctcctac cttacaaaca
     4261 tctggcgttg attttagata agtaacgatt gttacaggtc ttttctgcgg atcaagttct
     4321 ttagttaatt caactaaagg ttcaaaatat tctttagcac cttcggaatc cgaatctggt
     4381 tcatttgcaa tagaccacat tacaacactt gggtggttct tgtcgcgttc tatcaattcc
     4441 ttgatcaccg ttttatgaga attttctgtt cgtatctctt tccacgtatt atgtttttcc
     4501 acattatcat ctaataaagt ggccatgaaa tttaaatgta accctactgc aggtacttca
     4561 tcaataacta caataccttc tcgatctgct aatcgcataa tttcttctga gtaaggataa
     4621 tgtgatgttc taaaagaatt agcacctatc catttcatta aattaaaatc tttaatattt
     4681 acagcctcat tcaaaccacg tccattaaca tacgaatcct catgcttacc aaatccttta
     4741 aaataaaaag gtttattatt aatcaaaaat ttgccattgg taacctgaac actgcgaata
     4801 ccaaattctt ctgtataggt atcgatcact ttattatcat caattaaact aattttcata
     4861 ctatataaat aagcgtctag aggttcccaa aaaattggat tcttaagctg aatcattcct
     4921 ttctttcctt cagcttcagc tacaagttga gcctcttcgt catatatcgc tattaagatt
     4981 tttccggtcc attctgtatc gatattgaat tctacacttg catccaaatc agttattctt
     5041 gtattaatag taatatcact tatatagtct ttcggagttg tatataactt aacaggtcta
     5101 tgaatacctg cataattgaa gaaatcaaaa ttaactaagt tttccttttt tatatcccca
     5161 ttttcctgta ctgtttcctt cataatcccc acaggtaaag tactatcgtc aataatattg
     5221 tttacagcaa ctgtaattcg attattcccg tcttttacaa accgattaat ttcagactca
     5281 aatggtgtaa acccaccttt gtgttgagta ataaactttc cattcaaaaa aacttttgct
     5341 tcatgtgttg cagatccaaa acgaagaact aatctttctt ctaataatct tttaggaaga
     5401 gtcacttctt tttcatacca cacccatcca acatgatttc taatgttctc tgtttcaaat
     5461 aaatcattat aagaagaggg aactgaaatc ggataactct ctttttcatt tattggttct
     5521 aaagcaagtt cttcctgtaa gtcatcattt gtatctaatt taaatctcca gagaccgctt
     5581 aagtcaatta cttgcctcgt ctctgtcata atgggataca acatataaac cactcctatc
     5641 taaatattaa ataaatgtat cctttaaacc acaataagca tctattggac ttactccctt
     5701 aaattcagaa agacccatta gtttgtccac caatatttct aaagtttctt gttttccatc
     5761 ataagtatta atataagtct ttacttgagg tacatcagcc aaatgaaacg gacactgtac
     5821 agatacaaaa attgttggaa tttcatgaat gtaaaacggt atatccggag ttcctttact
     5881 tgctggccag acaattcgtt gaactgtgcc tggattaaca ttagctatat taatgatcaa
     5941 gtcatatttt ttagttaaat ttttaattgg tctcttagca gcatatattc cagctatatt
     6001 tttaattttt tcttcttgcg ataatccttt caattcttct tcaggtgaaa tgtatttttc
     6061 aacttcaaat ccttttgctg acaaaatctg tttcaataaa tcaatggctt gaggtctatt
     6121 tccagcaact acttcaccaa acccaccttt taccccatgt acatctacta gtaaaatcct
     6181 tttatatttt tctggtacaa taggccaaat atcttgttta tctttaacta atgtaattgc
     6241 ttggtcagcc acctctttaa aaattgattt attttcaatt aaaccaattt tttccagagc
     6301 ttcttgctta ggtaataaaa tttgttcttt tgcttttttg tgtaatccca atttagcttt
     6361 taaccctaaa attcttttta aggcatctaa taaccgatca tcagtgataa ttcctttacg
     6421 atagccttcc atcatataat taaagtcttc atctggatca ttaaaaaata gaaatagatc
     6481 acatccagct gcaatagaag tgggcaataa ttctgatcgt ttcattgccc cagtcattcc
     6541 taacatatga ctagcatcag taactactaa tccattaaat ccgagttttc ctctaagtaa
     6601 gtcagtgatt aattcttttg ataaagttgc aggaagtaaa tcttcatctt tcagatcagg
     6661 attaaaatgt tttgaataag ctggcatatg gatatgacct gccataattg aaggtaatcc
     6721 agcttctatt aagcctgagt atacttttcc aaaagaatta tcccattctt ccgtacctaa
     6781 actattaata ctaaaagata gatgctgatc tcgttcgtca ataccgtcac cagggaaatg
     6841 tttagctgca ggcaaaattc cactctcctg aatacctttc atataagcta aactaagttc
     6901 taaaacttta tcagggtttt gtccaaaaga tcgactagaa atgataggat ttctccaatt
     6961 tctattaata tctacaatag gagcaaaact ccagttacat ccaatagccg atgcttcaat
     7021 cccagaaact ctccctaatt cataagcata tttcgcatca tttgttgcac caatttttac
     7081 ttctacacca acttcagtac catctgtaca agctccgtta ccacctgctt ccgtattagc
     7141 agcaattaat agaggaattt tactttctgt ttgtaagata tagttttgat catatacctc
     7201 atcagcagtt cctggattat atcgtacagc tccaatatgg tactgattga ccatattact
     7261 caagtaattt ttatcacgac tagatcccat attaacaaac aattgaccta ttttttcttc
     7321 caaagtcata gaatcaatcg tctcttcaat ccaagaaata gcatcttcat ctaaattata
     7381 tggttttttt cgtaaatcta cttttatagt cattttcttt ctcctctact tattagtaag
     7441 atttttccaa aaagtatcta tatatttttg ttcaatatct acataatctc ccgataaaca
     7501 tttaaataaa acatcagttc ttaagttttc ccatgattct ttttctttat tgaccaaaat
     7561 aggataaaag aaaactttat ttttatttgc agcttctaga tcaccaggag aatcaccaat
     7621 cattaatatc ttatccaaat cacaaccatt ttcaattaca cttcgaataa tatcttcttt
     7681 ttttccttta tcttgacaac acagttcatc aactaatgat aataattcat gtctttccca
     7741 ttcttcttga acagcttcct tattagctga gcttacaata attatcttcc catatttttt
     7801 cagagctttt atagtatctc tagcacttaa aaagggttta tctaatcctt ttgcttgact
     7861 aatctgttga ttgacttctt ccgaccattt taaagctttt aataaatcct ctgactgaga
     7921 atattctatt tccctcttca aagatggatt agacaattct tttgttagag atacccagtg
     7981 ctttaatcga ttaatcgatg ttacatcatt tttttctaat gttttaacta aacctaaaaa
     8041 tctgtttatt ccacgagtct ctgaatataa attaatatta ttccaatcct gtaggaattt
     8101 ttctctatga tgaacatcaa aaatctctgc agcaattggt ccgaaaaaga gattgtgttt
     8161 ataagtcatc gtatccataa cacagccatc tgaatcaata caaaatatcc aattattcat
     8221 atttctctcc tatttatgtt tttgttttaa aagctcgcaa ttttctaaga ctttatcttt
     8281 agataatgga taaaggaaaa ataaaattaa tcctacaatc agaaaacaaa ttgatggaat
     8341 taatgttgaa gcgttatata acttttctaa aacatctccc gtttgtacat ttgctaaaga
     8401 gtcatagcct ataatagaaa gagtccaacc tccgacgcct ccagctagag cttgacctat
     8461 ttttctagca aaagaatata ccgcatatac ggtcccatct tctctttgat cagactttac
     8521 ttcttgatca tcaataacat cagtaatatt tgcccaaata acagtattaa acacacccaa
     8581 acccatatag ccaaccgaac taagaattaa gaatacatac atattactag cttttatcaa
     8641 aaataagatc aaatatacta ttgctgaaaa gaacattcct actgatgcca gttctttttt
     8701 tccatatttt ttacttaaaa acaaagttaa aggcgaaaca actattaaaa ccaaaatagg
     8761 attgataaaa ttcattaaaa ctattccctg tgcatcatta tagtaatcag gaaatacata
     8821 attattcata ctcataatta ataattgagc aaggagtaag aaaatagccg caccaattat
     8881 agaaagtaat gccctatttt taactaaccc ttttaaagat tttaacaatg aaactttgta
     8941 ttgagattgg tcaattctta ctcgttcagt agttagttta taacatatta aataacaaat
     9001 aagtgcacat atcgaaaata ttcccgcaac aattgtaaaa gttgatccac cacgaactat
     9061 ttgagcgcct gaatcatctc ttgtataaat aaataatggt gttaatacac caatgaccaa
     9121 acttgctaaa gtagctccaa catttcggaa tgtcgatagc attgttcttt cttctgtaat
     9181 agaagtaata gctgatgcca ttgatccata aggaatattt atagatgtgt aaaaaatact
     9241 cccccataat atatacgtaa catacatgta tactacctta acgctcatag aagctgaaat
     9301 catagaagtt tgatacatta aaaaacttgc taaagcgact ggaccactca ttcttaaaat
     9361 ccacggttta aacttaccct gcttagttgc tttcgatcta tcaacaatac gccccatagt
     9421 tacatcagta actgcatcga taaatcttgc tactaaaaat aatgttccaa cggcagctcc
     9481 gcttatcccc aatacttttg tataaaagat cattaaaaaa gaactagcaa aaatgaaagt
     9541 aaaatcgttt ccaaaatctc caaacatata tcctattttg tctcttatac caaattttct
     9601 ttccatacaa ttctctccct tctgttgtta agcgttttca ttctgatgaa agtacgtact
     9661 atactctgaa gcgtaaagag tcagtattta ttttttacat ttcagagtat tatttgtttt
     9721 ttctcctaat aattctttat ctcataaaac ttatctatat atttactagc tactcgactt
     9781 acttcttcaa aatcaccttt ttcaacagaa gccaataaat tcccacctac accaactgca
     9841 acaactccta cttcaaacca atcttctaag ttctctatac ttactccgcc agtaggcatt
     9901 atatttacgt gtggtaatgg agcttgatag gcttttacaa tggatggacc aaaagcagaa
     9961 cctgggaata gtttaatgat atctacgcca gcagtaagtg cctcctttat ctcagtaatt
    10021 gtcatacaac ctggtaaata aggaatttga tataaattac aaatctcagc tgtttgtcga
    10081 tcaaaagatg gactaacgat atattctgcc ccagccataa ttgcgatacg agcagtaaac
    10141 gcatctaaaa ccgtaccggc tccgattatt acatcttttt gatcagcata ttttttagca
    10201 atttctttga ttatttcttc agcattagga actgtaaaag ttagttcaat ccctttaatt
    10261 ccacccgcaa taattgaatt tattgcttta atggcctcat ccttattttt cccacgtaca
    10321 accgcaatga ctccagccgc ttctaactta cttaaaattt ctactttttt catatctatc
    10381 tccttccttt atggatacat actttgtcta gctgtactaa cttacaaaga ataaatttaa
    10441 gcttttattt caagtattat tttctacttc cgatttcaaa aaaattaaaa taattatacg
    10501 cattacgata acaaatattc tccactatct gactaagata catttcatca tctggaattc
    10561 ggcctgcttt aacccactcg cttagtaatt gacataatac tcgacgaaaa tactcatggc
    10621 gaggatagct tagaaaactt cgagaatcag tcaacatacc tgtaaaattc gacaacaaac
    10681 tttgttgtgc catcgtagtc aactgttgac gcattccttc agctgtatca ttgaaccacc
    10741 aagcacatcc caattggatt ttttgaatca tacccccttg gaagctttgc attgctgttg
    10801 ctagtggaag ccaatcagtt ggatttaatg aatataaaat tgtttttggt aagcacccac
    10861 tcttttcagc ggtatcgaac aatgctacaa cattttgtgt caaactagct tgatccccca
    10921 tcgaatcacc accgacatct actccaattt gttcctttaa tatacttgaa ttatttctta
    10981 aagcatttaa atgcatttgc atcgtccaac catatcttgt atactcagac atcaaatgta
    11041 attgaatacc tgtaacaaat tgtgcaattt ctgataaatg gaaatccgtt tttcctgcta
    11101 aagcttttat taacagattg tcgagtattt tttcatctgc tatttcataa aaataagtat
    11161 tcaaaccgtg atctgctaat cgacagccaa tttgatgaaa atgatccact cgttggctca
    11221 atgcttgctt caacccatta aagtctttga ttggtatagc cgctgtttga ctaagtttta
    11281 aaatatagtt cgaaaagcct gatgatttga tactccagac cttatctgga cggaaagtag
    11341 gtaatacctt gaaagaatta tcctgtttag aaagctcagt atgataccac aagtcatctg
    11401 taggatcatc cgttgtacag atggctttca catccatcat ctccaacaat tctttcgggc
    11461 gataggaatc cgtttgaatt ttttcgttag cacgtcgcca aatttctggt gcattcttct
    11521 cagaaattgt caaatcaata tcaaagtaac gttgtaattc caaatgagac cattcaaaaa
    11581 taggattacc tggcgccttc tccactgttt ttacaaaagc taaaaatttt tcataatcat
    11641 cacctggacc actgatcaac tcttcttcta taccattagc tcgcatcaat cgccatttat
    11701 aatgatctcc agctccttta tcatttaacc atacctgagt caaattcttg tattgcttat
    11761 tttctagcaa atatgctggg tctaaatgac aatgatagtc gataattggt tggtgttttg
    11821 caaatttatg aaaaagtctt ttagctattt cattctctaa taaaaagttc ttatctaaaa
    11881 acatatttaa acactccttt ccttccgtta gtttttagaa gagaaaattt ttcctctaaa
    11941 taaactccct tatataatta tttactcgcc cccttttcaa gcgcttccca aataccattt
    12001 aaataaactg cacctagagc tcggtcatat aatccataac caggtctacc ggtttctccc
    12061 caaatcatcc gaccatgatc tggacgaata tagccattaa atccattatc gtacattgtt
    12121 tttaatatct tatacatatc tagagaacca tattctgatt tatgcggcgc ttcgtaaaaa
    12181 tcgagtccat tgtcacttaa atatttgata ttacgaacat gtgcaaaagg aatccgatcc
    12241 cgttgacaaa attcagatag aatttcatag acatcattat ctggtcgttc tgcaatactt
    12301 ccagtacata atgtaatacc attagaagga gaatccacta cattacacaa ccaatctaaa
    12361 tcgtcacgat ttttaacaat acgaggtaat ccgaaaatgg aatatggtgg atcatctggg
    12421 tgaactgcca ttttaatccc aacttcttca catgtcggga taattgcttt gagaaaatat
    12481 gcaaagttct ctcgtaattt ctcttcatca acttctttat aggcttctaa taattgctta
    12541 atttgtgata accgatgagg ttcccaaccc ggcaattcaa aattattagt agaattttct
    12601 acttctctaa taatttcctc cggatcagta gggatatttt ttgaaatata ggctaacgta
    12661 gaagacccat catctaaacg ataatccaaa tccgatttta cccaatcaaa tactggcata
    12721 aaattataac agataacctc aatcccaaat tctgccaaat tgcgaatcgt ctgtttataa
    12781 ttctcaatgt attgatctcg tgttggtaaa ccaattttga tatcatcatg aacattaaca
    12841 ctctcaataa ctttcaaggt aagtccattg gcttcgactt catcttttaa agatttaatt
    12901 cgttctctcg gccaaacctc tccggctggt atatccatta atgttccaac aattcctttc
    12961 attgctggga tctgacgaat ttcttgtagt gagatttttt cttcatttgc cccataccat
    13021 ctaaaagtca tttccatagt tactttcctc caacttctgt tatatattta ttgattgttt
    13081 tacgaactgc ttgaggacct actagcattt cgcaaaagat tttttcagtt ttctttccta
    13141 ccccaacttg atataaatct aaaccaaaga tttctttatt ttctaaaatt tcctgtaccg
    13201 cacaatgaat ctttgaagga tcttgttcac ctaatttcaa tactgataat ttatcctgca
    13261 actctaccaa taacggatca ggacttggca caaaattttc cccttgatca tcgactgcca
    13321 gtaaataacg taaccaagca gcaatagcga taggaataaa tgttagattt tctgcatttc
    13381 cgtctttttc gacatacttt ttaattgttt caccatagcg aatcgctact ttttgagaag
    13441 tatctgttgc aattcgttgt ggtgtatctg gaatataggg attaggcaaa cgtttattaa
    13501 ttacttcatc aataaattgt tttggatcaa taatgcctgg attttcaact actggtaaac
    13561 cttctaaata acctattcct ttgattaaac caaccaaatc atcatcctgc atctctgctg
    13621 aaattgattg atatcctagc agacaacctg ttactgccaa agcagtatga agtggattca
    13681 agcttgtcgt aaccttcatg atgtctgctt tatcaaccgt ctctctatct gtcataatca
    13741 caccagcctt ttccaattta ggccggccat ttggaaaact atcttcaata actaaataat
    13801 gaactacctc agtattagtg aaagcagcaa tattggtatg tttttttgtg tgaatgatat
    13861 ctaaatcctc gagccccatc atcaatagat cttcctttac attctctgaa ggatttggcg
    13921 taattcgatc aatcatactc caaggaaaag tcactttttc tttatccttt aaataagcaa
    13981 taaatttttc agaaacatat ccttcttttt gccaagcttc tgcaatcgta aaaatactat
    14041 cttgaaaacg ttgaccattc tgtgagaaat tatcagtaga aaccatcgca atcggcaact
    14101 ctccagcatt aaatctgcta tataacaagg atgttacaat actcatcgta tgttgaggat
    14161 tgctaggtcc agatttgata tcagctttga ctaccgaaaa gaattgccct ttagaatctt
    14221 ttaaactgta acctttttca gtaatagtaa acgttgtaaa ctgtaattta ggatcttcaa
    14281 aatatttaac cactctttga tagtccgcta tattcttcgg attgcaatat aaactatcag
    14341 ccgttactgc caaaagtctt tttttgagtt caccatctcc actcataaca atttccaaaa
    14401 tgtcattgtt atagtcatga taagcttttt ccactacttc ttcatcaaat gtttcacaca
    14461 caactactcc tgtttctaat tcattttgat ctgctaagca ttgagcaatt tctgcatgaa
    14521 atcctcgata aagatttcct ccaccaaaat gaagccatac tggatgttgc tggccttctt
    14581 gcttaacttc tttgacatca aaacacggca gtagaatctg catttcattg aattcttcga
    14641 tagaattttg ccaattttta atcgaaacca taattaacct cctcaaactg atatgttagt
    14701 tttgatacat tttatatttt aaaacccatt gtaaccgttg tcaatataaa aagggaataa
    14761 acttgctttt ttctaccata tcagaatgat tgtatttttt attcagaaaa ataaaatact
    14821 ccttcttttt ggactgattt tatcgaaact tattttttct ttttttcatg tattctttta
    14881 tttttataac tagtgtatta cttcaaaatt tgatattata tggcatgaac agaattaaaa
    14941 tatcagttaa aataaaagtt aaggagcatt gtgtatgaca attaaaacta gtctccaaaa
    15001 tcaagcttac caatctattc gccgacaaat tatctatgct gacttagaac ctggaaaaaa
    15061 agtatcagaa aaaaaattag aagaaacact ttctattggt cgtacaccaa tacgtgaagc
    15121 actgattcaa ctccgacaac aaggtcttgt tgatacaatt cctcaaagcg gaaattatat
    15181 ctcattaatt gatttagatt cggccaaaaa tgctcgattt gtcagagaac atttggaacg
    15241 acaaattatg ttagagtgtt gtgccaaaat gaataaccaa aaaaaacgga ttttagaaac
    15301 tataatttca gaacaagaaa aagctgttag tcaaaaaaat gctcgtagtt tttttcataa
    15361 tgataattta ttccataaag cttgttttga aattgcagag cgagaagaag tatggcaatg
    15421 gttagaaaat aacaatacac acttagaacg atttcgatgg ctacgagtaa aaacggaagg
    15481 attaaagtgg gaaaaaatta tggaacaaca ttatcaacta tttgaggcat taacaaaaca
    15541 agatccagaa gaagctaact ttctaacatc gttgcatctt catttaatgc ttaatgagca
    15601 aaatattgtt ttagctactc atccaaaata tttcaaaaat atataacttt taactctttt
    15661 taaattaaat ggttgttctg atcagaaaaa tatcgctt
//
LOCUS       DAFELK010000065        15244 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFELK010000065
VERSION     DAFELK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.067"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            168..362
                     /locus_tag="LP433_002387"
     CDS             168..362
                     /locus_tag="LP433_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006516.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="LP433_002388"
     CDS             631..930
                     /locus_tag="LP433_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006517.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="LP433_002389"
     CDS             complement(1027..1461)
                     /locus_tag="LP433_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2006518.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="LP433_002390"
     CDS             complement(1693..2403)
                     /locus_tag="LP433_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL2006519.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="LP433_002391"
     CDS             complement(2393..3253)
                     /locus_tag="LP433_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBL2006520.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="LP433_002392"
     CDS             complement(3258..3896)
                     /locus_tag="LP433_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBL2006521.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="LP433_002393"
     CDS             complement(3911..4210)
                     /locus_tag="LP433_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2006522.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="LP433_002394"
     CDS             complement(4253..5737)
                     /locus_tag="LP433_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL2006523.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="LP433_002395"
     CDS             complement(5757..6218)
                     /locus_tag="LP433_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2006524.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LP433_002396"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LP433_002396"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBL2006525.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="LP433_002397"
     CDS             7521..8291
                     /locus_tag="LP433_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2006526.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="LP433_002398"
     CDS             complement(8564..9391)
                     /locus_tag="LP433_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006527.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="LP433_002399"
     CDS             9959..11194
                     /locus_tag="LP433_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL2006528.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="LP433_002400"
     CDS             complement(12193..12453)
                     /locus_tag="LP433_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL2006529.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVTHLNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="LP433_002401"
     CDS             complement(12480..13781)
                     /locus_tag="LP433_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2006530.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="LP433_002402"
     CDS             complement(14073..14531)
                     /locus_tag="LP433_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2006531.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..>15244)
                     /locus_tag="LP433_002403"
     CDS             complement(14544..>15244)
                     /locus_tag="LP433_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBL2006532.1"
                     /translation="KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITK
                     NFPSNIPNNYLEYYLYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVL
                     NFNFGEHGQYIVDIAISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEP
                     ITLRKPISDFHKGLMEAQVAVEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILD
                     EMIKVNKKYWPALK"
BASE COUNT         4876 a         3105 c         2365 g         4898 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgcccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatacttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcaaatgcgt
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacgac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttat
//
LOCUS       DAFELK010000066        15004 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFELK010000066
VERSION     DAFELK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.068"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(325..2322)
                     /gene="tkt"
                     /locus_tag="LP433_002404"
     CDS             complement(325..2322)
                     /gene="tkt"
                     /locus_tag="LP433_002404"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL2006533.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2424..2675)
                     /locus_tag="LP433_002405"
     CDS             complement(2424..2675)
                     /locus_tag="LP433_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBL2006534.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2822..3445
                     /gene="lexA"
                     /locus_tag="LP433_002406"
     CDS             2822..3445
                     /gene="lexA"
                     /locus_tag="LP433_002406"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBL2006535.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3624..3842
                     /locus_tag="LP433_002407"
     CDS             3624..3842
                     /locus_tag="LP433_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006536.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4130..4642)
                     /locus_tag="LP433_002408"
     CDS             complement(4130..4642)
                     /locus_tag="LP433_002408"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBL2006537.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="LP433_002409"
     CDS             complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="LP433_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBL2006538.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7095..7538)
                     /locus_tag="LP433_002410"
     CDS             complement(7095..7538)
                     /locus_tag="LP433_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBL2006539.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7539..8327)
                     /locus_tag="LP433_002411"
     CDS             complement(7539..8327)
                     /locus_tag="LP433_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2006540.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8324..9265)
                     /locus_tag="LP433_002412"
     CDS             complement(8324..9265)
                     /locus_tag="LP433_002412"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBL2006541.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9442..10029)
                     /locus_tag="LP433_002413"
     CDS             complement(9442..10029)
                     /locus_tag="LP433_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBL2006542.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10250..11557)
                     /gene="obgE"
                     /locus_tag="LP433_002414"
     CDS             complement(10250..11557)
                     /gene="obgE"
                     /locus_tag="LP433_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBL2006543.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11851..12861
                     /gene="gap"
                     /locus_tag="LP433_002415"
     CDS             11851..12861
                     /gene="gap"
                     /locus_tag="LP433_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL2006544.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12946..13881)
                     /locus_tag="LP433_002416"
     CDS             complement(12946..13881)
                     /locus_tag="LP433_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2006545.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            14067..>15004
                     /locus_tag="LP433_002417"
     CDS             14067..>15004
                     /locus_tag="LP433_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBL2006546.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEA"
BASE COUNT         4231 a         3317 c         2640 g         4816 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acaaacttaa ttaattaaat tatactttta attctcaaga aacacaaact
      181 aatccgaaga attctttgtt ttgtcattta aatgtaacat agccgaaaac gaaaagtaat
      241 attgatttat tcttctaaca cataaagaac agctgtctcc aacttgcaga cagctgttct
      301 tatcagtcaa acaattgctt ggatctatga tagttgattg tacgtattca cgacattttc
      361 tactgtaaat ccaaattctt ctaaaatttt agtgccaggg gcagatgcac cgaaatgatc
      421 gattgtaatc gttgcgccct ctgttcctac gtagcgttcc caaccaaatg atgcagcagc
      481 ttcgatagcc acacgtttct tcactgattt aggaagtaca ctttctttat attcagaaga
      541 ttgtttttca aagaggtcaa agcttggcat agaaacaaca gaaacatctt tgcctttttc
      601 agccaattct ttttgagctt tcacagccaa atcaacttca gaacctgttg caatcaaaat
      661 accttctggt gtttctcctt gtgatggaga aagaacatac gcgccttttt tcaccatttc
      721 atctgctact tcttttgtag aaggcaatac tggaaggttt tgacgactca atacaaggat
      781 agtaggcgca tctgttgtct ccatcgctac tttccaagca gcacgtgttt catttccgtc
      841 tgccggacga atcacttgaa caccaggcat gcagcgaaca gatgctagtt gttcaatcgg
      901 ttcgtgcgtt ggtccgtctt ctccgacagc aaccgagtca tgtgttaaga cgtaaacaac
      961 aggagtatgt tggattgctg ctaaacgaac tgctggtctt agataatcga caaagacaaa
     1021 gaatgttcca ccgtagatac gagttccgcc atgaagttgg ataccattca tagccgaagc
     1081 cattgcaaat tcgcggacac cgaaccagat gttgcgtcct tcataatgtt caggagtgaa
     1141 atctttatct gcagccacca ttgtattatt ggaacctgac aagtccgctg aaccacccca
     1201 gaagcttggt atagctttcg ataattcttg gatgacttct ttacttgaaa cacggcttgc
     1261 ttgactgctt ccaacttcat aagttggcaa ttctgcatcc cagttttctg gtagtttgcc
     1321 atcaaaagca tcttcaaatt gttgtgctaa ttcaggataa gcttttttat aattggcaaa
     1381 catttcattc catgcatctt cagctttttg tccttcttct atcatcgttt gatggaagcg
     1441 ggcagctact tcttctggaa cagtgaaatc tggatactcc caaccataaa cttctttagc
     1501 catcttgatg ccatcttcac caataggagc accatgaaca gcagatgttc cttctttagg
     1561 agcaccatag ccgatgactg tttttacttc gatcaatgtt ggtttgtctg tttcagcttt
     1621 tgcttcttca atcgctttag agattgcttc taggtcattt ccgtctttca ctaagatatg
     1681 ttgccagcca tatgcttcat agcgagcacc aacgttttct gtgaaagctt ttgaagttgg
     1741 accgtctagt gaaatatcgt ttgaatcgta taaaacgatc aatttcccta gtttcatatg
     1801 acctgccatc gaacttgctt cttgagatac cccttccatc aagtctccgt caccgcatat
     1861 tgcatacgta tagtgatcca tcacattaaa gttttctttg ttatacgttg ctgcaaggtg
     1921 cgcttctgcc attgccatac cgacagccat tgcaatccct tgtcctaatg gccctgtagt
     1981 ggcttctaca ccatctgtgt gatgtacttc aggatgtcct ggtgttttag aatcccattg
     2041 acggaattgt ttcaaatcat cgattgtcac ttgatagcca gctaaatgaa gcaagctata
     2101 caacattgct gacccatgtc ctgccgaaag aacgaaacgg tcgcggtcag cccagttttt
     2161 tgatgtcgtt ggatttactt tcaggtgttt tgtccataac gcatatgcca taggtgctgc
     2221 gcccatcggc aatccaggat gtcctgagtt tgctttttgg actgcttcaa tacttaatgt
     2281 acgaattgtg ttaacgccaa gttggtcaat tttgtcaaac aaaataaccc ctcctattaa
     2341 tttaggtttt ttttaccttt atttcttaca ctttcattct ataagatgtc acacgaaaaa
     2401 gcaatctttt tcagtatttt ttactaaaag ttgtcatttc ggttgtgtaa gccttttttc
     2461 ttttggattt cttttaattt ttccggggtc acgtcattgc cctcaggatc gacgactttc
     2521 attccttcga tatgatgacg cataccggaa cgaaaagctt ccaaatactc tttgcgtaag
     2581 ttgatttgtt cttgttcttc ggcttttgag agaccatttt ccttcttttt acgtgcaagt
     2641 tcattgatcc tctctatttt ttcaggtgac agcatgctca gccctccttt tactctcctt
     2701 catattatat aaaaactgaa aaaaaaacaa ctagataaac taaataaaat acgaacattc
     2761 gtttgattta gcgcttttta tatggtacta tttatttatc aagtgaaaga aggtgtacct
     2821 tgtggcccga caaactgaat caagacaaat cgaagtctta cgatatatcc atgaacaagt
     2881 aacccaaaaa ggatacccgc cgactgtccg tgaaatcggg gaagctgttc agctttcttc
     2941 tacttctact gttcacggtc atcttgcacg gcttgaaaaa aaagggttta tccaaagaga
     3001 tccgacgaaa cctcgtgcaa tcgagttgac aaaacaaggt ttagaaaaga ttgggattcg
     3061 tccaacaact attccagtac ttggcgtcgt aacagctgga gaacccattt tagcagtaga
     3121 ggatgcttca gacttctttc caatccctcc taatctttct tccgaagaag gcagtctctt
     3181 tatgctgaca attcgtggag atagtatgat caatgctggg atcttggatg gtgacaacgt
     3241 gatcgttcgg aagcaagaaa ctgctcaaaa tggcgatatt gtcattgcaa tgactgccga
     3301 ggacgaagcg acttgcaaac gattctataa agaaaaaaac tttttccgtc tgcagcctga
     3361 aaacgacttg ctcgaaccaa tcatcttaga tcaagtatct atattaggac gagtagtagg
     3421 actttatcgt agtcatatct attaattgct actaataaaa gaaaactttt taaaaagagt
     3481 ttgagacgat ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc
     3541 acttccctct ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc
     3601 ataaattaac gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg
     3661 ttttgttttt aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg
     3721 ttccgttatt tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc
     3781 ggcgcagaat tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat
     3841 aataaggatt gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga
     3901 caaaaatcgg tcacatcctt ttttcgaata aacggtgttc taaagccagt ttttcggtat
     3961 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat
     4021 ttataaaaaa atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt
     4081 taaaatcgct tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca
     4141 ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga
     4201 tcaaaaatgc gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt
     4261 tgattgttcc tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa
     4321 tggcatcctt atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga
     4381 tggtttctcg aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat
     4441 aagcaacagg acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc
     4501 gtttttcttt tgcataattt acgatttgct tcgtagcttc ccgataagcg tcaccatctg
     4561 ccatcagtgg ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg
     4621 caatataatc ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg
     4681 gtaggaatat cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgccgctgg
     4741 tataatctgc tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg
     4801 ttctctattg taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt
     4861 tcagggatac gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct
     4921 tgagaatgga tcagtttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa
     4981 taggcctcat caggcgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa
     5041 acttctttca gatccgctaa atcatctgga caatccataa taactagaga gttcggtttt
     5101 cttttttcaa ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg
     5161 ataatctcag gcacgaattt caacgtagaa gaatcaaatg ctaaataaag gctaccttcc
     5221 gacgttcggc tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc
     5281 acagaaaaat cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa
     5341 agctttccta ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca
     5401 aaagcgaccg catcaagctg actcgatgca ttggaaagga caaatttcag atgctgttgg
     5461 tttgctccga ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa
     5521 ggattatccg taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact
     5581 tcatttggca gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga
     5641 tgatcgacta tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc
     5701 gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca
     5761 agcatttcaa aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct
     5821 tcttttaaag taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca
     5881 atgcccaaaa cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta
     5941 ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg
     6001 atctcattca atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac
     6061 gagacggcag gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa
     6121 aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc
     6181 tgaagtccta tccgttctga atgatgaatg gcattgattc ctaatgaaac aaggattcga
     6241 ttctcatcag tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat
     6301 tctacaggcg gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc
     6361 aaatctggaa atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct
     6421 ggtaaattct caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga
     6481 gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt
     6541 ccttcttcga tcttttcttg gtatacagat tggtttggtc catacccatg ctcaaatcga
     6601 tttggcagga atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt
     6661 gcactggtga tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt
     6721 acagcttctt ggattcggct gattgcttta tccatatcgt gcatcagata cggatcatgt
     6781 aattcttgtt cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt
     6841 tgccacagta acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag
     6901 gattcagaag gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca
     6961 ctcctaactt agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa
     7021 aaacagatca gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt
     7081 atgaaatatc cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt
     7141 tcttccggcg ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa
     7201 gcagcttcca actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct
     7261 tcaattttct tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt
     7321 tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc
     7381 agcgcagaac cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt
     7441 acaggaacat ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat
     7501 ccaagaatca cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg
     7561 ctggctaaat aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa
     7621 ataaacggtt gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc
     7681 aacttggcag gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca
     7741 gccttatcga agaaatctgt ctcgattgga cctggattca ctgtcgtaac agctacgcca
     7801 agtggtttca attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca
     7861 gaataaaccg ttgattttgc agttgccatt tttccagcca tagacgcgat attaatgata
     7921 tgaccttgtc ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct
     7981 aagatgttga cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg
     8041 aaaatcccaa aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc
     8101 ttttcatata attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc
     8161 tctttgccgc tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt
     8221 gcgcaactta taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga
     8281 ccgcctgaac tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct
     8341 cgcgaaatgg aatctcaatg ctatcaaaat ctttcatgat cgtcgtgttt tcaaacactt
     8401 cttgtgcttc tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag
     8461 taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg
     8521 aatggaaata gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca
     8581 gaatatcgct attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa
     8641 tagtcacgat tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc
     8701 catcttctag ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa
     8761 tacctaattc ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac
     8821 gataaccaaa actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat
     8881 cagtaaaaat cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg
     8941 tttgcgaaat acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct
     9001 ctaatggcgt atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa
     9061 tatgatcgcc gtgtaaatgt gtaataaaaa ttttaccgat ttttctcgga cgaatagtcg
     9121 ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct
     9181 cgtctaaaag tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac
     9241 ctgttcctaa aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt
     9301 ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa
     9361 cgttctaaag cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt
     9421 gagatcctct gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt
     9481 ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc
     9541 tttcgcatca tgcacatctt tttcgacatc ttcataatcc aagcgggtaa tttctccgcc
     9601 taattccatc attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat
     9661 cagtcctgta gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc
     9721 ttttatttct ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa
     9781 aatccctagc ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga
     9841 tttgttatta ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg
     9901 atcatggctg acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt
     9961 gatttctgaa aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg
    10021 tttgctcatt aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgta
    10081 aaataagaaa agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta
    10141 tcacagctcc tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct
    10201 cccttaaatc tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa
    10261 attcaaattc aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa
    10321 gagcttcatc cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat
    10381 gatcgaaatt cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg
    10441 catctgaatc acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag
    10501 tttcttcttc cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg
    10561 ctgtagcatt caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg
    10621 ggatgtcatc agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta
    10681 gattttccgg tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta
    10741 gcaagcgtaa gttataagta gataattctt tgttgatggc aagatagtct tcataaggat
    10801 ctcgtccttc catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat
    10861 gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca
    10921 agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttagggacga
    10981 gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag
    11041 tcgatttccc gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta
    11101 gttcgatttt tcgctcttgt cctggttcgc cgttttcagc aatttccggt gcaggattcc
    11161 gaggagaggc aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg
    11221 tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg
    11281 ttccttgtgg tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca
    11341 tcccattttc acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac
    11401 gtaacccttc atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg
    11461 gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc
    11521 cagctttcac atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt
    11581 attcatttat ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta
    11641 tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt
    11701 ttatcatttg gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa
    11761 tattctttgc gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac
    11821 agcaccccta ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt
    11881 gggcgtattg gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta
    11941 gtagcaatca acgacttaac aagtccaact atgttagcac aattattgca atttgactct
    12001 actcatggta cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc
    12061 gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac
    12121 ggtgtagata tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg
    12181 catttagatg ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc
    12241 atcgtctata acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt
    12301 tcatgtacaa caaactgttt agcacctatg gcttatttct taaataatga atttgggatc
    12361 gaagttggta caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga
    12421 cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat
    12481 tctactggtg ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa
    12541 ggacacgcac aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg
    12601 aaaacaaaag taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat
    12661 ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa
    12721 ggttcgatct ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt
    12781 aaaactgttg catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta
    12841 gaaaaattcg ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat
    12901 ccagtcaaag gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg
    12961 gcttaaaaat tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc
    13021 atgctcggct ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt
    13081 atctaacatt tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg
    13141 ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac
    13201 ttttgtcact agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc
    13261 tagctgataa gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt
    13321 cacattatct ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac
    13381 accgtataga acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg
    13441 tacatagtct ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg
    13501 tcctcttgca tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt
    13561 ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt
    13621 cgtttcagca ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca
    13681 atcgcttcgg ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg
    13741 tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt
    13801 ataaaaataa ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag
    13861 gattttcatc caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg
    13921 aattagtata atcaaagaat ctctactatg caatgttcat ttttataacc cgcgaattgt
    13981 aaaattaagt tagaaaaata aaaaggcatt tatggtacac tcaaattgta tttccgacga
    14041 aagaaaacaa aggagtgtaa ccataaatga cctacaaaca tcttaccata gacgaactga
    14101 caatgataga atcatattat cttcaacata ataagccggt tgaaatcgct aaccgaatgg
    14161 gacgtgctat acaaactatt tataatgtag tcaataagtt caagcaaggc aagactgctc
    14221 ttgattattg gcaccagtat aaagaaaata agaaaaaatg tggtagaaaa gtcattcaat
    14281 tacctgctca tgaagtagat tacattaaag agaaagtcac tcttggttgg acgcctgacg
    14341 tcattatcgg gcgaaaagaa aggtctgttt catgcggtat gagaacactt tatcgtttat
    14401 tttctaaagg aatatttgat attgacacac taccgatgaa aggtaaaaga aaacccaatg
    14461 gccatcagga aaaacgggga aaacaacagt atcagcgctc aatccatgat cgacctgata
    14521 attatcctga tttcaattct gagtttggtc accttgaagg tgatacgatc gttggcattc
    14581 atcataaaag tgccgtcatt actttagttg aaagattatc taaagtcatt atcacgatta
    14641 aacccaacgg ccgtaaggca ttagatattg aaactgccct taatcaatgg ttttctcgct
    14701 tccctaaaaa cttctttaaa tctattacgt ttgactgtgg aaaagaattt tctaactgga
    14761 aagccattag taaccaacat gatattgata tatattttgc ggaccctgga acaccttctc
    14821 aacgcccatt aaacgagaat tctaacggga ttctgcgtcg taatggactg ccgaaatcaa
    14881 tggattttag aaaagtgaat cagacattta tttccagtgt cagcaatcaa cgtaatcata
    14941 ttccaagaaa atcattgaat tacagaacac caatcgaaat atttttgagc tatgtacaag
    15001 aagc
//
LOCUS       DAFELK010000067        14441 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFELK010000067
VERSION     DAFELK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.069"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(58..855)
                     /locus_tag="LP433_002418"
     CDS             complement(58..855)
                     /locus_tag="LP433_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2006547.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSVPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVIKAISQQLKDVTSIFKLPKAVGKLLGSIQTNLPESVLLDCGMDFL
                     KDNNKKIDTLSVPVDGSWDFNDNTPSGSVLELDLTKNQEAIKKFLNN"
     gene            complement(947..2110)
                     /locus_tag="LP433_002419"
     CDS             complement(947..2110)
                     /locus_tag="LP433_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL2006548.1"
                     /translation="MKKRKKIDWWILGPYLTLSMIGLLEVYSASSYRLLQADENTKSL
                     LLRQLIFIFLSWSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGA
                     QRWISLFGIQFQPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPK
                     IAGALMILSIAWVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNH
                     AYERIATLRDSFIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIF
                     SIITEELGLIGALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVG
                     SIAGLMPMTGVPLPFVSYGGTSYLILSLGIGITLNISSKIQAEELPLYRPEKQ"
     gene            complement(2627..2833)
                     /locus_tag="LP433_002420"
     CDS             complement(2627..2833)
                     /locus_tag="LP433_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006549.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2849..3463)
                     /locus_tag="LP433_002421"
     CDS             complement(2849..3463)
                     /locus_tag="LP433_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBL2006550.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETKEAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(3610..4293)
                     /locus_tag="LP433_002422"
     CDS             complement(3610..4293)
                     /locus_tag="LP433_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL2006551.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RSNTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(4402..4860)
                     /locus_tag="LP433_002423"
     CDS             complement(4402..4860)
                     /locus_tag="LP433_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBL2006552.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4944..6707)
                     /locus_tag="LP433_002424"
     CDS             complement(4944..6707)
                     /locus_tag="LP433_002424"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBL2006553.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6928..8388)
                     /locus_tag="LP433_002425"
     CDS             complement(6928..8388)
                     /locus_tag="LP433_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006554.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPVLFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(8596..9522)
                     /gene="glsA"
                     /locus_tag="LP433_002426"
     CDS             complement(8596..9522)
                     /gene="glsA"
                     /locus_tag="LP433_002426"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBL2006555.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(9545..10972)
                     /locus_tag="LP433_002427"
     CDS             complement(9545..10972)
                     /locus_tag="LP433_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2006556.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYYMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(11003..12217)
                     /locus_tag="LP433_002428"
     CDS             complement(11003..12217)
                     /locus_tag="LP433_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBL2006557.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(12558..12800)
                     /locus_tag="LP433_002429"
     CDS             complement(12558..12800)
                     /locus_tag="LP433_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2006558.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(12832..13389)
                     /locus_tag="LP433_002430"
     CDS             complement(12832..13389)
                     /locus_tag="LP433_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2006559.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(13402..13590)
                     /locus_tag="LP433_002431"
     CDS             complement(13402..13590)
                     /locus_tag="LP433_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL2006560.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(13603..14169)
                     /gene="amaP"
                     /locus_tag="LP433_002432"
     CDS             complement(13603..14169)
                     /gene="amaP"
                     /locus_tag="LP433_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL2006561.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKRSRVE"
BASE COUNT         4307 a         2970 c         2365 g         4799 t
ORIGIN      
        1 aaaagaagtc agaacataac atagattgtt atttctaact tcttttattt tctttactta
       61 attattcaga aattttttga ttgcttcttg gtttttggtc aaatctaatt ccagaacact
      121 tccggaaggc gtattgtcgt tgaagtccca actgccgtct actggtacgg ataatgtatc
      181 gatcttttta ttattgtctt tgaggaaatc cataccacaa tccagaagca cactttctgg
      241 aaggttcgtt tggatactac caagtaattt cccaaccgct ttgggtagct tgaatattga
      301 agttacgtct ttcagctgct gagagatagc tttgatcact tgctctcctt tgtttatata
      361 tacgccatct aaatctagag atttttctgc atcgatcttg actccaccag gaaacagttc
      421 attaacgcaa tcgataaaat cttgaaatgt gatacttgca taatagggag cttcaaattt
      481 gaaattttcc tttaatgttt gatttaataa atcaactccc ccataagagt aagctgcatt
      541 tatcttattc attccgtaac ctggaatatc gacatatgaa tctctcatga tagagatcag
      601 ttttgcttgt tgtgttttct ggttgtattg tgcaaccaga agtgaatccg agcgaccgtt
      661 ttcgtctttc gaacgagcat ctgaaccaat caaagccaca tttagtgtgg tagggacact
      721 tttcggctct acctttttca cagttgaact ctgttttgca gacgaaaatc catggataaa
      781 ctcaatcgaa aaatagccaa ctactaatgt aagcagtaac aaaatagata atatgatttt
      841 ttgagatact ttcattgcga attcctcttt ctaaaagaac ctctcgcttg aaaaataaaa
      901 gattgtactt tatgataatt caaactgaga gtttctcagt ttctctttat tgtttttcag
      961 gtcgatagag cggcaactct tcggcctgta tctttgaaga aatattcaac gtgattccga
     1021 ttcctaaaga aaggatcaga taacttgttc ctccgtagct aacaaatggc aatggcacac
     1081 cagtcattgg catcagcccc gcgatacttc ccacgttcat tatcgtctga acgaatagca
     1141 aagttccgaa tcctaaaaga aacaatccag cttgctgatt tttacagcga ctgcttaaac
     1201 aaaagattct catgcataat gagaacaata agaaaagcac acacaatgca ccgattagcc
     1261 caagctcttc tgtaataatc gaaaaaataa aatctgtttc tgtctctgga agataccctt
     1321 tttttgtgat actatttcct aatccccgcc caaatatgcc accattatat agtgcataaa
     1381 acgaatgggt catttgatag cccgcaccat gactatcgat aaaagaatct cttaaagtcg
     1441 cgatcctttc ataagcatga ttaaacatct gtggaagcca acctttattt cctaaatata
     1501 ataccccgcc tgctgctcca atcagcaatg cagaaaaagt aacgattaga tagatccctt
     1561 ttttaaatgg aaccgccgct gcccaaaata tgacccacgc aatcgaaagg atcatcaatg
     1621 ctccagcaat ctttggctga aataaaatca gaaaagttat acctactgta atcaggaatg
     1681 gtttttttag atcttttggg ctactatttc cgtcacgaaa aaaccagctt aaataaaaaa
     1741 tcaaaaaaag atttgccagt tcagaaggct ggaattgaat gccaaacaga gagatccaac
     1801 gttgtgcgcc gttgacagtg acaccgaata tccctattct tactaatact aaaaagaaaa
     1861 tcgataaggc taaaccgtat cctgctattt tagggtgaag taaatagtgt agtttgactg
     1921 aacgagctaa gaagatcacg ctccaactca aaaatatgaa aattagttga cgcaataata
     1981 gactttttgt attttcatcg gcttgcaata aacgataaga actggcactg tatacttcta
     2041 aaagaccgat catggacaaa gtcaaataag gacccaaaat ccaccaatcg atcttttttc
     2101 tttttttcac cgcatctcct cctcacacag caatccactt gtcaggtgag gagcgagttt
     2161 gtctcatcaa ataagtcagt cacaaaaata taaagaaaag gtcagaaacc ttttcgaaca
     2221 agaattctga cctagcatca tctcatcgtc cgagttttag cactatacaa cgtaaagaaa
     2281 acattcttag ctattggaaa aagccttaat ccgacagttt ctgttttacc cattggcgac
     2341 tttcgacgtt tctgggcaac agcctatgtt tgtataggag cctcacctaa caaggttatt
     2401 actatattct atttacgagt tcatgataga cttttcctaa tgattaggca atggaatttg
     2461 aaatgaaata gtgaaattta acaatcttta atatttttta gaaaaaaata acaaataagt
     2521 tgaaagaatc ccgttgcaaa ttctttcagt tgcaccagga ttctttgata attttttagt
     2581 tttatgtgtt tttttatatg tttttttcac ttttcggaat aaatatttat ttgttaaagt
     2641 aattaaacaa tccgctaatc gtttgatctg gcatttctat ttccttacca tctaaagtaa
     2701 cagtagtaac gacaaaatgg tcttgcaatg gcggaacttc taagtactgc ccttgcagaa
     2761 aatcattcac tgtttcatat tcttttttca tttcttttga atctgtcgat ggtttatagc
     2821 ttatttttaa cataactagt gctccttttt attcgggacg tgcaatcgtg aaaatttctc
     2881 ctattgctgc ataatcattt cctgccaaac ggcttacagc attcaatttt cttggatcga
     2941 tccttcctgt cttatcatca tagactgttt catttaaatg atatttctgt acttctagca
     3001 aaaataaatc agctgttact ttatttttat tccgtatctc gacatgttca tataaggatg
     3061 tttcaaaacg aacttttgct tctgtcaatg ctggtactga aatgattact gaatcagtta
     3121 aagtcaagtc agtcaggtac agttcgcttt cctcattagg cagattggct gctgttttat
     3181 ttacttcttc tacgttgtcc tcatcaagga tatggataac agcttctttt gtctcaagaa
     3241 tattctttgc tgtgtctttt actgcatctt gttttctctg gatcgccaag gataagatgg
     3301 gtcgattcga actgacgata ttgaagtaac tgaagggtgc gatattcact atatcttttg
     3361 ctgatttagt cgttactact gctactggtc tagggatgac tgaaccaatc agcaacttgt
     3421 aattttcacg ttctgtcaat tctgaaggac tccgttcaaa catggtttcg ccttctttct
     3481 ataaaattcg ttaaaaagca gatcttgaag acaaaatgaa aagtaatgct tttttcatct
     3541 tcttagaatc tgctttaaac tatctatcaa tttttctttt ttgtcaagaa tctgtgccgt
     3601 gcgtgttttt tagttatttg ctttacttgc ggcttcgaca tatcttttag tgatcaattg
     3661 cggacgggtg ataatagatc caactacgac tgaaaaagca cctaattcat atgctttctc
     3721 tacttgttca ggagagtcag tatgtccttc cataattact gggatatcga cttgttctat
     3781 gatttgattc aataaatcaa aatcaggtgt ctgcgtcttt cgtgaatatt ctgtatagcc
     3841 tgctaaagtc gtagacaaaa gatcaaaacc atcttcttgc gcttgaagcg cttcctcaaa
     3901 agtcgaaata tctgccatag ctaaccgacc gtgttcgtga atcatttgga caagttcagc
     3961 agttgttttt tctgtcggac gtttacgaga agttgcatcc agtgcaatga tttctgcttg
     4021 cgtctccaaa agttcttcca cttctttttc tgtcgcagta ataaacactt ctgacccatc
     4081 gtaatctctt ttgataatcc ctattaccgg taaatcaacg attcgcttga tttcattgat
     4141 atcttctgtc gtatttgatc gaataccaac tgctccgcct tcttttgcag ccaaagccat
     4201 tctccccata ataaaagaac tgtgtagcgg ctcgttttcc aaagcttgac aagaaacgac
     4261 gactccgcct ttgatttgtt ccagtgtatc cacaatatct cctccagtaa tgttatataa
     4321 aaatacagct tcatataaaa atgtaaccct tttctattca ggagtcaata atgagctatt
     4381 tctttcagca gacctttctt actaaaagaa aattacttca aattcttcgt atacgaccag
     4441 cttctcttct gtaaattcta tgttcaacgc ttctttataa gcatgtttaa aaaactcagc
     4501 atggactttc cgccaataag ctaatgtccg atccccttct ccttctttcc aagcatgctc
     4561 tttcgtgact tcactaaaag gcaagatggt cacatttata tttttgatga tacaaactgg
     4621 ttcatttttt ccattcagga ccacgtctaa ttgaccaact tttggtaaag gctcattctc
     4681 ttgtttatac agatcgtaac cacttgatgt accagtcttt atctttttta caactagttc
     4741 gctcaactcg tctgccattt tttctgtatc cccaaatgaa aagaaaccta atttttctga
     4801 ttgataacta ggatattttt cttggaactt tttgacatat tcttctactt gctgatacat
     4861 aacatccacc cctttgcttt ttataatgaa aaaaccatcc agatactagt ataaacaatt
     4921 atctggatgg tgagcataat gaattattga atattcaaga cacgcagact atcttcaacg
     4981 atttgttttg gtgttaaatg ataacgttca taaagctgcc ctacaggaac gctatccgtg
     5041 aattctttct ctgcaccaaa atttaatacg ttcattgaag aatcaccata ataacgactg
     5101 atattttcgc caaatcctcc tgacaaacta ccatcttcta atgtgatgac taattcgtgt
     5161 gtttctttta atttatctaa tgtttctacg tcattttctg tgatcgttcc tggattgatc
     5221 aacgttgctt cgattccttt ttttctaaaa gcttttactg tttcttttcc taattcaaga
     5281 aaaccgccta aagctaaaat tgctactttt cctccattat ttactgtttg ataggctgga
     5341 atactataat catttgcgat agctgtacca tgttctacac catgtgtagg aattcggatt
     5401 gctacaggct gcgctgtttg ttcgaacgcc caatctagca tagagatcat atcctctttt
     5461 gttgctggag caagatattt gatgttcggg atacttgata agtaaggaat gtcaaatgtt
     5521 ccttggtgtg ttcggtcact agctgagatc gttccgccac cgactaaaat aatcactgga
     5581 ttctcgttga tcgctaaatc atgtgataat tgatcatatg cccgttgcaa gaaagtactt
     5641 gattggaaga cgactggacg tactccctga gaagccaaag cagaagcgaa agtgatagag
     5701 tgctgttcag cgatccccac gtcaaaataa tgatctggat gtttttcttg gaatgttttc
     5761 agtccaaagg cgcctggtat cgctgcattg actgcggcaa taggagctgt acttgtttgc
     5821 attttcttat ccaaataatc catgatgatc atattaaatg tttctccaga agttacttgc
     5881 tttgcctccc cggtggacag atcaaatggt acatgccaat gatatttcat tttattatcg
     5941 attgccggct gataaccgcg acctttttcc gtatggacgt gaagtacaat cggatgatca
     6001 atatctttta cttcttcaaa taaacggatc accgtttcca gatcgtttcc attatccacg
     6061 taacgataat caaatcccat tgctttaaat aggttattgc tgcttttacc gttggtttga
     6121 cgaagctcag ctaagttttt atataaactg ccatgattct catcaataga catctcatta
     6181 tcgtttacta atacgattag attggattgt aaaacaccac cattgttcaa tccttcaaaa
     6241 gctaagccac cacttaggga gccgtcaccg ataaatgcta ccacatttcc tgattctttc
     6301 ttcagatctc tcgctttagc taaacctgtt gctaagctga tagatgtaga tgtgtgcccc
     6361 actgtaaaat agtcatgttt actttcatgt tggttggaat atccgctcac ttcacggtaa
     6421 tgtccttttt caaaaccatt ttttcgacca gttaaaagct tatgaccata agactgatgg
     6481 gaaacatccc aaacgatttt atcctttggt gaatcaaata cataatgaaa cgcaatcgtt
     6541 aattctacta cacctagatt cggaccaacg tgcccaccta catcgctgtc cttttgcaag
     6601 attttttggc gcatctcttc tgccaactgt ttcatttcct caacagataa ttttttgaca
     6661 tctgcggggc tattgattgc atccaataca tgtaatactg tactcataat acattctctc
     6721 ctccgtacta tcttctttta atgaaaatag atttgttaca ctttatctat tctactactt
     6781 agagttgact ctaagtcaat agcattttaa aaaaatttca gagaaagctt gttatataag
     6841 tagatcttcg cacgaatcag gactcaaata aaaaccttct acagacaatt aaaaagcttt
     6901 gtagaaggtc tcctaattaa ggtctcatca agaaatatgt ttttttaata ggtgaagttc
     6961 ctgagcaata tgatacaaat ggatgtttgc accttttaat gagattggat agatctttgt
     7021 cttttcagtt tctaatccat tttgatagct agcagcatcg cacaaaacca ctcttttttt
     7081 cgcacataga cattcatcag gcaattcttc taatgaacga aataaaacag gatttatttc
     7141 agcgatgcct tcttccgcat acaaatgaaa ttgggttcga taaaaaaatt gtttgactga
     7201 actttctgaa acaacaaaaa tttctatttc ctgtctcccc gcttgttcac tgttgatcaa
     7261 agaaagactt ttgacgaatt ttcgaatgaa attttcattc catcttagtt ggatttgatt
     7321 tttctttttc cactcttcca atatttctac aatttttccg tacagaagtt gttctttttc
     7381 tgatagaaga tagatccttt ccggtaaaaa tacttgtcca tctgcccaca acgtacggac
     7441 aaattgtaaa aaggattgct tgaaaataaa attttctgca tcgtcgattt cagcgatact
     7501 aataatctgt aaaatcaatt cattcagtga taggtcattg agaacaaaat ttttataaac
     7561 aacttcgaaa tcttttctta acagctccat gttctcattg gtataatttc tactgttgaa
     7621 caaagaaaaa atataataga catcttcttc ttgtaagtct agaattcctt tttgctcttc
     7681 caatccttga cagactaatt gaaataacgg cttcgtttct gcgcttttct tatcttcttc
     7741 tttcagtcca aggggaaatg cctttcttcc gattgcgatc tctattcctc gtatgataaa
     7801 ggacttttca tcttccgaat atcttctttt aaaaaaatga gtctctacat aatcaatcaa
     7861 ctcgttacaa gcttcttcta catacggatt tttattttca tagccttccc aattgacata
     7921 acgtactaaa gctagcaaga tgttccgcga gtcaaattct gggataatga tttctttatt
     7981 tttcaaataa tcattttctt taaaaaaatc caatacgatt tttttgattg tatatacttt
     8041 gctcaaagaa ataaattcaa gatcagccag ttctgtactc gtgaatatac cattaaaata
     8101 ataacttaaa aactttaaaa aataagattg accgtacaga aactgtgtga gctcagaaag
     8161 agcaatacca tgtttgaata cgagtttata cttatgcttc tctcttactt gttcttttat
     8221 acaatattct agacactcgg ctagactttc tagatcgtga aggatcgttg gtgtagtcac
     8281 ccttagagaa atagctgttt gttcgatgtc tatttcttgg aattcaaata attgttcaca
     8341 cagatacact tttctaaata tatttcgctc gatgtaattt tccagcattc ctgatacacg
     8401 cctccagttt ttcttatgat tttatttaat catatctgta aatcgtattt ttgtttcctt
     8461 tttatttaga aaagcccttt caaaaaccaa taaaaaaaga aactgggaca aaagtcaaac
     8521 aagctcacaa tttcagcctc attgtaggta gctttgagcc gtttggactt ttaccccagc
     8581 ctctttcaag aatggttatt caaagatgtc agcgtctagt tctttgacta catctttcaa
     8641 caattggata ccagctgcgc tgttaccaaa tggatctagt gccgggctga agacacctat
     8701 gccgtaacga tttggcacag ctgccatcaa cccgccgcct acaccgcttt ttgcaggtac
     8761 accaacatgg acggaaaact ctcctgattc atcatacaaa ccagcagttg tcataattga
     8821 tttgacgatt gtagcacttt cttcagtaat gatttgtttg ccattccaag gagcaattcc
     8881 tttatttgcc agcacagcag ctaattttgc tatgcctgta gcggtgacat tgagggagca
     8941 ttgtctgaaa taagcatcga gtatctccgg tacgtctcct tcgatcattt gattaccttt
     9001 catatagtaa gcaagagagc gattgatatc acctgttctt gattcagaat gatagatttc
     9061 ttcattcaat gtgatattag gatcatcaca gatctctttc ataaatgaca agattcgctc
     9121 aaatttttca tctgcatctt taccggcaat caacgaggtt gttgcaatcg ctcctgcatt
     9181 aacaaaagga ttcattggat gtttgcgatg attgatttcc atattcatga tagaattgaa
     9241 ggcaaaaccg gttggttccg tgttgattgt ttgaaagact ttttctattc cgttgtcttt
     9301 gattgctaat aacaatacgg gaacttttga catgctttcg atggcaaagc gcacatcggc
     9361 gtctcctccc tcaatcagtt gttttgtatc caaatcataa atcgccatac ctaattgttt
     9421 gggatccact tcagctaatg ctggaatgta atccgccact tgtcctgttt gataatagtg
     9481 gaaatttttt ccaatcaatt gttctaattc ttttacttcc atttgaataa ccagctttca
     9541 ttttttattt ttctgcatgc tggaatttat gacggcatgc gtagatcgta aatggaataa
     9601 ctaagacgat aagataagaa acaatcagaa tcgtttcata aatcccatgc tgtccagctg
     9661 cgatactagc aggtggaaca aatgagatac aaaaagcaaa aagtgaagtc aaaagaccta
     9721 aacaagcaac gattactttt acaacttttc cgcctggaac ctgataggct ctttcaagac
     9781 tgtcatcttt aaaaaccagc ttcaaatagc ccgcgaaaaa catatagtac aacatcaggt
     9841 agattacaac agtcaatgac atcgctgcaa gaaatgaaag attattcccc ccgccgctta
     9901 atgtaaagac ggctgcccag attgttgcaa cgatcccatt tgcgatcatc aaatgagcag
     9961 gaacaccgtg tgtgttttct tttgcaaaat attcaggaag taatccttct tctgctgcta
    10021 cgtgaagtgc ttttgaagga gaggttaccc aagaagcaat ttctccgatg acacctaaac
    10081 aaacaagaat cgcaagaatt ttcgcaatcc atgcaagatt tggatcaatg tgtcttaata
    10141 ggaattctaa cgattgaatc acccctgtat taagagacaa accatgttga ggtactgtag
    10201 tagcgacggt caatccgcca aaagtatcta aaatgattgc cagaataacc aatacaaaca
    10261 ttgctaatgg ataatccttt ttagggtttt ccatttcatt tgcatgactg gcagatgttt
    10321 ctacgcccat atatgctaaa ataaaggaaa caaaaacaac cagcgtaggc aatttcgaaa
    10381 aatcaggaat caatgttttc atagacagta tcgtttgtag tggagcgcct gaagcgacat
    10441 aatggatccc taagccaaac aagactaatg ctggcaacaa gataccagct acaaaaccga
    10501 tccgagcaat caatgaagtg tatttggttc cttttaactg tgagagtaaa atagcccaga
    10561 aaataatcaa taggattgcc aatttcagat atttattgtt ttgtatagca ccaatacccg
    10621 ttgcatagga taatgcacca gttaagaaat acagcatggt caagtagcca actgttatct
    10681 caaaccattg gaaaaagatt gcggcaaaac cgaatcgttt tcccaatgtg cgactgaccc
    10741 aagtatagac accgcctttt tcccatcctt tcaccgttgc catctctgct gcgcacaatg
    10801 ccacagggat aaaccatagc aaaccgccta ataacaagaa aaatactaag ctgaagcctg
    10861 aggtcgcgaa tgtgggatat tcatataatg aaacgaccat tgagatggtc atagccaaaa
    10921 agccaaagaa cgttaatttt tttgcaggaa ttttcgtttt gctttgttgc atgaatcttc
    10981 ctcttttcta tttgaatttg tttcaattga gtttgttgcc aaagaagaaa aagtccaatc
    11041 cttcttcttg ttcttctttt gtagtagtga tcgttgtaaa gtgcatcgcc gattttaaaa
    11101 tcactgttgt cagcacatag gcatacacgg cagtaatgat gacaccaatc acttgaatcc
    11161 ctaagaagta ccagctgctt ggattcgtta gtaaatggct gttagatgca aagatcccta
    11221 tcagaatcgt acctgtgaat ccgcccatgc catgaacacc ccacacatca agtgcatcat
    11281 cccattgttt ctttttacga aaatcaacag cagcatgaca gacgataccc gcaatgatcc
    11341 caatcagcat ggcacttttt gcttctacat aaccggcaca aggcgtaatg gctgccaatc
    11401 cagcaacgga tcctgttagt acgtcgacaa aatcaaagcc atttcctttt acttttgcaa
    11461 tgatcagcca agtaatcatc gcaaatgcaa gagcgatgaa tgttgaacca aatgcattga
    11521 ctgcttgttc atctgctcga agtgcaccac cggaattaaa accgaaccag ccaaaccaaa
    11581 gcagtcctgt accgatagca gctgccataa gactgctatg ctgacttctt tctcctaaag
    11641 gaatctttct ttgaccaagt gtgaggatac atgctaaaga gccgaatcca gctgtcgtgt
    11701 ggatgactgc tccaccagcg aaatctctaa atcccatctg atccaaaaat ccgccacccc
    11761 atatccagtg gcaaacaggg aaataaatca gcagattcca aaaaataaca agtataatat
    11821 agccttttaa attcaatctc cctgcaaaag ctcctgtcat caaaggaacg gtaatcacga
    11881 taaacatcag ttggtaaaga aagaacatta aaaatggaat cgttgcacca tgaaacatgt
    11941 tggggaagct tgtaacatgt ctcatcaaaa agaaatctgc cgggtttcca ataacaccgc
    12001 cgatatcccg tccaaaggcc aatccgaatc caccaaatac ccacataatc gttgttatcc
    12061 caacggagag aaaagattga gacatgatcg ttagtatatt attcttccgt gctaatccgc
    12121 cgtaaaaaaa agctagacca ggagtcatca ggcaaaccat tgctgtacat aaaatcatga
    12181 atgctgtatc tcctgtattg ataggtaatg tattcatttt tttcgcctcc tttctacgat
    12241 tacgagtata aaagaaggtg tagttgtttt tttcttctgt ttttttgaat taatacttgc
    12301 atttataaaa gacagacaat taataaaagc ttgatgtgtt gtgctctttt tcgtttttca
    12361 cacaaataaa gacaaaaaat aaacggtctt ctttttatag aaaaccgttt attttcgtct
    12421 ttttttattt ttaaagatat tttttcataa ggaataaaga atacttcata taaaatatat
    12481 aaaaaagaac cgcagcgagt gtcgctacgg ttctcaaatt tgttcttcat ttcaacataa
    12541 gtttttcttc aatttgctta taatttacgt gcaaagaatg aaacgactaa tactaaaatg
    12601 attgcaccga tcaatgatgg aatgatagcc attcctgcaa ttgttggtcc ccaagttcct
    12661 agtaaagctt gtccaattgc tgaacctact aaaccagcaa tgatgtttgc gatgatcccc
    12721 attgatgatc ctttattcgt gattgctcct gcaattgctc caatgatacc gccgacgatt
    12781 aatgcccaaa taaatcccat tttaaattcc tcctaactga cttcttactt cttattgtac
    12841 acgtggttcg ttattttctt tgactttttg tgcacctttg cctacagcag attttgcttt
    12901 atctgtttgg cgtgaagcaa attgtcctgt ggattttgct gcttctgtta ctttgtcttg
    12961 tactgtttct tgatcttttt ggtattcttc ttgtgttttg atgtctgcaa cattcacatt
    13021 cacttcgata acatctaaat gtgtcatatt gtttacttca gtactgatca attctttgat
    13081 ttggttgtaa atatcttcga tgtctttacc gtattctacg atcacatcta gatccacagc
    13141 tacttgtttc ttacctactt ctgtattgat acctgctgtt acgttatctg tgttgactaa
    13201 tttttcagcc atatttgaga aaaatccgcc atctaatgtc aatagaccat ctacatcttt
    13261 caatgcataa ccgatgattt tttggatgac tttgtcttca taagtcaatt caccattcat
    13321 catgcggttt tctccttttt catttgccaa aactgatcca tttgttgtat tcatgttttt
    13381 gttttccatc tttgtttcct cctatgattt aaaaaattga tcaactattc ctgactgttt
    13441 caaataaaaa ccgattcctg cgccaattgc tgtcatgatt atgatcaaca atgtcttgaa
    13501 aaatccaatc gttaaccata aaacagctag cagtagtcca agacccccaa agataatagg
    13561 gagcttgtat gctgaaaata gttctttcat tatttggccc tcctattcca ctcgagagcg
    13621 cttgtagtct cttgtatctt cttgttcttc ataaccgctg tatgtgactg ccactttgac
    13681 cgtttctttt gttccgagta ctttagttac ttcttcttcg atatcttgca tcaatacacc
    13741 tgttttccct actaatgaag aagttcgttt caagtctccg ttgacatgga tatggattcg
    13801 atttttcgtt gaacgtatcc gtactttagg tgaatgaatg aactcttctt cgtgtaaatg
    13861 ggaacgtacc aacccttcga tcgctttttt gtcgattgtt agtttgccat cttcccgttt
    13921 cataacgaaa gttcctcttg actttggata gaaaagaacg actagcaaga tgataatagc
    13981 aagaacggca aatactacag ctgcccagaa aatatattgt tgcatgtagt aattcgttaa
    14041 agtaaagaag cgaaatcgtt ccaattgttc aggcataata tacggcgcat tgatcaacgc
    14101 aatcgctaga aatactgaaa gtagcagtaa actcatgata acaccgatta tttttaaccc
    14161 cttattcatt ttccacctcc tataaactta tttttaccct gtaaataact ctaccgacaa
    14221 tcacagtata gatagcgaac agttagcata gcatcagtaa ataaagcgct accaaacatt
    14281 gctggatcat aacggcgttt tattgccagt ctgatactga aataacaatt gcttacttat
    14341 tctctattta cttttgattg ctggctatac ttaaaggata ttattcaaga ttaaaaattg
    14401 caaagattat gctcagttat tattacaaga ttctatttat t
//
LOCUS       DAFELK010000068        13705 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFELK010000068
VERSION     DAFELK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.070"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            39..491
                     /locus_tag="LP433_002433"
     CDS             39..491
                     /locus_tag="LP433_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006562.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            505..1194
                     /locus_tag="LP433_002434"
     CDS             505..1194
                     /locus_tag="LP433_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006563.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1319..3670
                     /locus_tag="LP433_002435"
     CDS             1319..3670
                     /locus_tag="LP433_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBL2006564.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3750..4145
                     /locus_tag="LP433_002436"
     CDS             3750..4145
                     /locus_tag="LP433_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006565.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4470..5087
                     /locus_tag="LP433_002437"
     CDS             4470..5087
                     /locus_tag="LP433_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006566.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5128..5427
                     /locus_tag="LP433_002438"
     CDS             5128..5427
                     /locus_tag="LP433_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBL2006567.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5461..5628
                     /locus_tag="LP433_002439"
     CDS             5461..5628
                     /locus_tag="LP433_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2006568.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5673..6278)
                     /locus_tag="LP433_002440"
     CDS             complement(5673..6278)
                     /locus_tag="LP433_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006569.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            6403..9390
                     /locus_tag="LP433_002441"
     CDS             6403..9390
                     /locus_tag="LP433_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBL2006570.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMPSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            9539..9748
                     /locus_tag="LP433_002442"
                     /pseudo
     CDS             9539..9748
                     /locus_tag="LP433_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9883..10065
                     /locus_tag="LP433_002443"
                     /pseudo
     CDS             9883..10065
                     /locus_tag="LP433_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            10041..10397
                     /locus_tag="LP433_002444"
     CDS             10041..10397
                     /locus_tag="LP433_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2006571.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLT
                     NIENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVT
                     IGKVIQAIYGEKCKFN"
     gene            complement(10911..11078)
                     /locus_tag="LP433_002445"
     CDS             complement(10911..11078)
                     /locus_tag="LP433_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL2006572.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(11166..13091)
                     /gene="tet(S)"
                     /locus_tag="LP433_002446"
     CDS             complement(11166..13091)
                     /gene="tet(S)"
                     /locus_tag="LP433_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_063856411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HBL2006573.1"
                     /translation="MKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSGTTKTD
                     TMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAILLISAK
                     DGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIKQTVNL
                     NLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSLYPVYH
                     GSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLYSGTLH
                     LRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGDKKRLP
                     HREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIVLSFLG
                     EVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASIGLSVT
                     PLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKYCANIL
                     NTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAFQPRRP
                     NNRIDKVRHMFNKINLH"
     gene            complement(13107..13160)
                     /locus_tag="LP433_002447"
                     /pseudo
     CDS             complement(13107..13160)
                     /locus_tag="LP433_002447"
                     /inference="COORDINATES: protein motif:HMM:NF019687.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4614 a         2121 c         2494 g         4476 t
ORIGIN      
        1 atatattata aatttaataa gaaagcgagg tgagaatcgt gaaaaaaacg atactaagta
       61 ttttttcagt atttacaata ttaattgggg gctattttct tttgaattta gattctgtta
      121 attcaaacgc tcaaataaaa gatcaaagag tagctgaaca taataataaa aaaatgagtt
      181 tgaccaaaaa tatctattct atgtcagatg aagaattgta taaagaattt ggtgatttat
      241 ccggggaaca gttagaagaa agtattccag gaattagtga ctcagataaa attgttgtct
      301 tgtctgctgg tgggcaatta atgggagatg gcaaatccga attagttagt tataaacaaa
      361 atcacagaca gtttattgat gttaatactg attccaacgc tatttcgatt aaggatctaa
      421 aagagctttt aaatagtaaa agaaatgaat taaagcagat aaaagaaact aattcagtgg
      481 aattagagta aaggaagatt cattatgaaa aagatttttg gtgtttctgt tgggctactt
      541 atgatgttaa catttggaaa tgcagtatat gctgctgaga aagaagttat ttcagatcca
      601 gagcagtacg cctcacgata ctttgctgat tttgaagaag aagataaagt acttgcattg
      661 ccagaaggtg gttttttaaa aggggaagct aaaattgtat ctatggataa tccagatata
      721 attcaaggtt catataattc agaaactgat cctgcttcag tttcagtgac agaagcaaaa
      781 aaaattgttg ctgaaaaatt caaaaatgat attgaaacta ctccaattat gcctcgagga
      841 gcatttccac ccgatgttgg tactagcgga caccttcttg tactagcagg aggaggaagc
      901 tataaatcac agccatttag tggtgcggga tggcgttttg gaggtatggg tgtaaaacca
      961 gctgatggta caggcaactt tttacgttgg aaatcctaca ttgacgatgg aagagtagga
     1021 aatgtaaatc aagccaacgc aactaaatct ggttctattc aaggaatggc attgtatgct
     1081 cgtgaaggat tcaaatactt tgcaccaaac gggcctggtt ggacaatgaa tataggtatt
     1141 tattacactt ataatcctgt tgcaggtacg tattatgttg ttcaaaatat ttaataaaac
     1201 agcacaaaga gatttctttg tgctgtttta ttatttttag ttgttgacaa acactaaaat
     1261 ataaaatata atcaacacat aaacgaacgt atgttcggca agaaagcagg ggatttttat
     1321 ggatgagatg gttttaagta ctcagaaatg gctaaacaag aaatacagta atgttacagg
     1381 gtttgataag gttccagaaa atgggcgaac agggtggcct acaatctatg gacttattga
     1441 aggactacaa gtagaacttg gtattactaa tctagtagct aattttggac ctaccactga
     1501 aaaaatgtac gataatcagg ttactcctaa atggggcaaa aatctaccta aaaatattgt
     1561 atttcttatt caaggtgcct tttggtgtaa ggggattaat ccaggtggct tcgatggggt
     1621 atatactcca tatttagata ctgctgtaaa agagttgcag actgatgcag ggtttaatgg
     1681 aagcgctgta actggagttt tggatgcgaa atgggccaaa gcgttatttg atatgagtgc
     1741 ttttgttctt gttcccggcg gagatagtaa aattagaaaa atgcagcaat ggttaaatgt
     1801 aaattattta gaatacacgg gaataatgcc ttgtgatggt atttatcaaa gaaattcaaa
     1861 tcaagcatta atttttgcat tacaagctga actaggatat tctcccagtg aagcaacagg
     1921 gtcttatggt aatgggacaa ctagtaaaac ttatcctgtg tctgaaggta actcgggaaa
     1981 ctatgtaaga ataattcaat atggattata tgttaatggt tattttgaag acggtacatt
     2041 cgatggtatt ttcactaaat atatgggttt agaagtactg gcattccgaa aatttatggt
     2101 attgcctgaa tatactgaaa tagcagatgt tgttgtaata aaaggactat tgtctagcgc
     2161 tggagatatt agaagatctg cagatggcgc agatacttct acgcaattaa ctagatctca
     2221 aatccaaaca ttggttgata atgatataaa aatagttggt agatatctta ctggtactgt
     2281 tggaattgga aaagatgaac gaaataagta tctaactaca gaggaattga ataatatttt
     2341 ttctaaaaat ttatctgtgt ttcctatcta tcaagatgga ggtgcagcat tagcttattt
     2401 tacttatgat cgtggcttat cagatggtaa gaaggctata gatgcagcaa aaaatctaaa
     2461 tataccatta acaacagtta tttattttgc tgttgatcta gacatgttag gggaagaaat
     2521 tcttgcatat gctggagaat attttaaggg ggtatctgct gtaatgtcat atagcgggta
     2581 tcaaacgggt gtttacggaa caagaaatgt ttgttctcaa ataatcaata acgggtatgc
     2641 ttcgtttgca tttgtttcag atatgtcgac tggttatagt gggaatttag gttttcctat
     2701 gcctagacaa tggtcttttg atcaatttgt tgaatttacc ataggaagtg gcaacggagc
     2761 tgttggtatc gatttaatcg ctacatcggg tagagatagc ggatttaatg agttatcaaa
     2821 tgatactaat aatgataatt acattgccaa atacaatcag aaggttataa atcagatggt
     2881 acgtgcgtat caatatctat cacaagctgg tcttgataat ccttggaacc ctcatttgac
     2941 attttataga tatgtaaatt attctggttt gtcatgggac atcatttctt ctcctgtaac
     3001 agagcatgat agaaaaattt atgatgaata taggaataaa ttaactaata gcgagggcct
     3061 gtataattat tttatagatc ctaatactgg ttcaataata ggtttgcctc acttaattgt
     3121 gacgttacaa tcacagatgt ttctagccga cacaatcaat gatagtgttt ctgactttgc
     3181 aggttggtta ggagatttaa tgacttgctg gggtgaagtt aagaaattag gaatacaaat
     3241 ggagcaaggt gtatttgcat tagtaggtac ggctgcaggt ggaacattta gtctagaaga
     3301 tttataccaa gatgttgacg cggtaaatgt ttatacctta gcaaaaagaa attctgattc
     3361 aacagcttta tcggctttaa aaacgtacta ttgtgataag ggtgctattg atagatttaa
     3421 tcaatttgtt aagaacagat ttggttcttc agataaaatc gcttcagtaa caaatagttt
     3481 attagaaaat gacgaaacag ttgatatctt aggtgtaggg ataatttcat ttttcattga
     3541 taaaatagtt aataattcac ttgggacaga ttttacttat cttgatttta ttggagatga
     3601 ggggaaagtt gcaaatggat tttctgaaaa aattattcaa tttcaagaaa atagaagtaa
     3661 acttaattaa gaatcgttta ctatttaaac agtgtccttt tcctttttaa atatatacga
     3721 taaaataagt atatgaattg taaaaggaca tgatgattat ggaagaaata gaatggaata
     3781 atctgactca aaataataaa aataattctg gatgtggaat tatctttatg tttgttatag
     3841 ttttgggaat agtagtactt ttaataactg tcaagatagt agattacttt gcgaatactc
     3901 ctgaagaaca aatacagaga aaacttcctg agtttgaaag agtaccacct tatgatccaa
     3961 gagataattc atttcaagta aaaaaattaa aagagtctcc aaatgaaatg tggtttgaag
     4021 ttacagttga atcaagcgac ttcaaagaaa aaaagaaaga atacaattat attgtaaagg
     4081 caaaagtatc aaaaagattt atttttaacc ctaaattaga aatatatagt gttgtaatag
     4141 aataatagtg ttaaaaaaat tgtaaaagtt aaagaagtca aattctgatg tgaaaaataa
     4201 aatataccat ggaagacata aaagaaaaac tggataacta gtttatttaa tggcagaccg
     4261 ttaaggcctg ccatttttat gtattttagc ggaataaata taatcatgcg ggagtgtaaa
     4321 cttactgttt caaaaagtat actttttgac atgccttgat tttctttgtt tatgtatggc
     4381 ataataacca cataatacaa tttgaaacgt ttctgattta atctgattgt tttgaaacaa
     4441 ttttagtgaa aaaagggtag ataaaaacga tgagaaaatt tttttatatc cgggtcagta
     4501 gttatgatca atcgatcgaa cgacaactga tttccgcgaa ggaattagga atccctgaag
     4561 aatatatatt tgtagaaaaa gccagcggca aagattttaa acgccctgaa tatcaattaa
     4621 tgaaacggat gtttcgaaaa ggagatttac tctatctaca atcattagat agactaggca
     4681 gaaataaaca aatgatttta gaagaatggc gagaattaac taaggaaaag cagattgata
     4741 tttctgtgtt agacatgcct ctgttagata ctgctagtta caagcaacta gatgggttag
     4801 agacgcttat ctctgactta attctgcaat tactcagcta tatggccgaa gacgagcgga
     4861 aacgaattaa tagccggcaa agagaaggcg tagaagctgc gaaacaaaag ggtgtaaaat
     4921 tcggcagaaa gaaaattgct ttacctcctg aatttcctgc gatctattct gactggaaag
     4981 caggaaagat aactgcagtc tatgctatgg atcaattggg catgaaacga aatacctttt
     5041 atcgacgggt gaaagaatat gaacatacct tgcaccactt ttcttgatag atataacagc
     5101 tattagacgg gaagggagag tttgaaaatg gacttaacga atcaaagggt cgtttttact
     5161 ggaacgctgc agcaaatgac acgaacccaa gccatcggtt tggttcactc tttaaacggc
     5221 cattgtcaat caagtgttac ttcaaaaaca aatttcctgg tttgtggtca gtattctaag
     5281 tcgttgtttg atgattctct ctatacaaaa aaggaacaaa ccgcgcggga cttgattgcg
     5341 ttaggtcatg agattaccat tttatcagaa gtcgaatttt atgcgttaat tagtcaacag
     5401 ttgaaagaat ggcaacggta tttataatcg ttagtaaaat ttacaaggag gaaaattttt
     5461 atgaagcgaa aatcttatga tcgttggggc attgaaataa ctagttttaa tcgaaatatt
     5521 gcttttcacg tggagtgtga ctgtggggaa ttagcaaaaa gtgtttatca aaaaaattac
     5581 ttttactgtc ctaaatgcca tcgccgatac ggggtacatg gaacatagaa acgaaatagt
     5641 gcggtagaaa agcgaatgaa tgtagtatat ttctacaaat cattcgcttt ctttatttta
     5701 taaatagttg gtcgagagat cccgttttct tttgcaatct ctgcaactgg aatgccttgc
     5761 tttaacatgt ccaccacggt tttaaaaact aagcgttttt gcggatctgt tgagttaata
     5821 gaatactcga ttggtcgtcc cttatatcgg ccggcttttt gagccaataa tactccttgc
     5881 cgctgacgtt cacgaatttt ctcacgctcg ttttgtgcaa tataacttag cagtgataaa
     5941 aacatatcga acatagcggt atccaggagt tcatttccag tattaaaatc taaaaactgt
     6001 gcatctaata tttttaacgc tacttttttc tgtttcataa aagcaactgt attttttata
     6061 tcttcataat ctcttcctaa acgatctagt gatgtaacga tgacgcaatc accttcacgg
     6121 atataattta gtaatttttg aaactcagga cgctcagtat ctttaccact ggctttttct
     6181 tggaataatt tatcaatgtt aagtccttcc atcattgcca attgtcgatc caaattttga
     6241 tcttgtgaag atactcgaat atagccaatt tttcccataa aaaactcctt tttaaaagtg
     6301 atataattta catgtaaaat ttacttgtag ttttactgct atcatagcat ttttaaaaat
     6361 aaattttatg tagacttaaa atttacttca tggagggttt aaatggatga aatcaaaagt
     6421 aacaaaaaag catttggcat ttatttagga gaacctagta cagaacaatt aaaccaattt
     6481 ttttatttgc atgaaaaaga tttagaattg atggagacta tacgacgacc agctactaga
     6541 ttaggttttg cactacagtt agtctcacta cgttttttag gaacttttat attagatctt
     6601 accaatattc cccaaaatgt attgagttat gtagcaactc aactaaatat tgatcctgga
     6661 gaaattatct actatagcag gagacagacc aggtatcagc acacaaaatt gataaaatca
     6721 cattatggat atcaagattt caaccaaccg gaaatagaaa catacctagc taactggctt
     6781 ttaaatagag cgctgtatac aacagaatct tcagatatgt tgtttgatat gcttctaaaa
     6841 aaatgtctgg atgaaaagat tgttttacct ggaattacta ctttttctcg ttttgttgct
     6901 agtgcaattg aaaaagctga agagcattta taccgacaat tgtctttggt tccaactgaa
     6961 gatgagagaa agcggcttct caatcattta gaattaattg gaactccagt ttatggggca
     7021 ataatcaaaa tggacatttt gagaaccccg ttagctgacg atagtcataa agaaatagcc
     7081 agaggttttg accgactaaa gcaatttcaa gctttctcta ctgaaaaatg gaagatggaa
     7141 tctattcctg aagggaaaat aaaagttctt gcaaattatg catttaaagc taaagctcaa
     7201 ttaattcaac gaatgagtga acagaaaaaa ctggcgttgt tagtggcatt tattttcata
     7261 tacaaacgta aggctatgga tgaacaaatt ttagcactat ctaatttttt tgaaactgtt
     7321 tttagacgcg ccaaaaataa ggaatctaaa gaacgtcttc gtaccataaa agatctagat
     7381 cgagccgcat cgacactttc agatattgta gatttagtaa tgcccagtca ttctgatact
     7441 aatgaactat cccttcgcga tcgtatctta gaaaaatatt ctgaggaaaa tgttaccgaa
     7501 gctgtatcgc aagttcggct attggttaaa aatgatcgtg aaccaatagc catttctgaa
     7561 cttctgaaca cttatcgaaa gttcagaaaa tttattccgg atattttaac tacactaaca
     7621 tttgacagca atgactacgg taacaactgt aaggaactct ggaccttcat taataataga
     7681 tttcctaagc cgattactta caaaatgttt ggagctatta aacatactct tccaaagaaa
     7741 tggatttatt acattcatga ataccctgaa caaactaata aatgtgtatt gattgcagct
     7801 gtcgaattgt taattcaatc tttaaaacgc catgatattt atattcctca gagtgtctta
     7861 tataacaatc ctatggattg cttgattgat gagaaaactt gggttcaaca aaaatacgtt
     7921 ttattagaac aactagatct tccttcttca gcaaatgaaa tgtctttatg gttaaagaac
     7981 gatttggaac tgtcttataa agaagcgcta aatcgttggc ctacttctaa aatggccaga
     8041 atagaaaatg cagatcgcct ggttgtctct agacttaaaa agacatatga aaaaaaggaa
     8101 gataagtctt ttagacgtcg cattcagcag ttacttccta aaattgattt gtcagatttg
     8161 ttattggaag taaaccaaca gttaaatctt actcaatcat ttaaccactt aagtgacaag
     8221 gacaccaaaa tgaaagactt ggatattagt ttattagcag ttcttttatc agagtcctgc
     8281 aatattggtt tttccccggt ttcaaaagaa ggatttgatt ctttaaagta tgatcgtctt
     8341 gtctatgtca atcatcatta tattcgagtg gatacacttt caggagctaa tcaaaaaata
     8401 atacatgcac acaggaaact tgccacctct aagatatggg gtgatgggca tatggcttca
     8461 gctgacggta ttcgttatat cacaccacaa cgttccctat attctagaag taatccaaaa
     8521 tattttggcc gtggtcgtgg gatcacattc tacaattttg tctctgatca atatataggg
     8581 ttccacggaa tggtcgtttc agggacactg cgagattcgc tttaccttct agaaggattc
     8641 ctcaatcaac ccagcgaatt aactcctaat cagatcatga ctgatacagc tggttatagc
     8701 gatatgattt ttggtctctt tggcttatta gggtttcaat ttagtccaag aattgccaat
     8761 gataaaggaa ccaaactttg gcgaatcgac gctaacgctc actacgggga acttgatacg
     8821 ttgtctcaaa attcaattaa tatggaactg atttataccc attgggagga cattcttagg
     8881 gttgcaggtt cgttgaaatc tggaaaagtg aatgcaacag aattaacgaa atctcttcaa
     8941 cggaatgggc aacccacgcc tttaggaaaa gcaataactg agtatggaaa agtttataag
     9001 acgaaacatc agcttcgtta tatttctgac gaaatatatg cacggcaaat tttagaacaa
     9061 ttgaataagg gggaagctcg gcatgcctta tgccgtaata ttttttatgg acgaaaagga
     9121 aaactctacc agacttatta tgatgggatg gaagagcagc tcaatgcatt aggattagtt
     9181 actaatgcca tcatatattg gaactcactg tatttagaaa aagtatttga acaaatgaaa
     9241 gctgaaggat tcgactgttc cgaagaaatg atacgcaggc aatctccact aattagtgat
     9301 cacatcaatt ttgttggtaa gtatacgttt agatacgaag ctgaattatc caacggtaag
     9361 ttacgtccat tgaatgtaga agaattctag caatgttcgg gttttgcatg ctaccgcact
     9421 atttcgtatg actgttccag cgaatcactt cgaatagaaa aagagaaaaa cacgagaaca
     9481 gcgttaaatc aacgtttctt gtgtttttac ttttgtgcta ccgcactatt tcgtttctat
     9541 gttccatgta cccctttatc aagaagcgca aacacgccaa attgccgatt ggttgatcgg
     9601 catgaacgca agccctttat ataccttgaa tttacaacaa aaaggcgtac aaggtacatt
     9661 ttcattagga cgtgtacaaa caccgacttt atatctcatt tatcaacgcc aggaagcaat
     9721 agaaaacttt aaaaaagaac cttttttcct gaataattca tagttttact aatagtcttt
     9781 cctaacattg atttaatagt ctttaaaggg ttctgttgca aagttttaaa tctactatca
     9841 aataaggtag aataatagaa aaagatagca ggaggaatga cgatgaatca ttttaaagga
     9901 aagcaatttc agcaggatgt gattattgta gccgtgggct actatcttcg ttataacctt
     9961 agctatcgtg aagttcaaga aatcttatat gatcgtggca ttaacgtttc tcatacgacg
    10021 atttatcgtt gggtgcaaga atatggcaaa ctactctatc aaattttgat ttcaaaccat
    10081 tgggtcttgc gattaaagaa gcccgtctta gtaaaggatt gactcgtgag caggtaggat
    10141 caatgatcca gattgcgcca cgctatttga cgaacattga aaataaagga caacagccaa
    10201 gttttcatgt tgtatatgat ttagtgactt tgctaaatat ttctttggat ggatttattt
    10261 taggggaaga aaacagtcat aaaagctcca aacgtcttca agtagaagca cagttggatt
    10321 gtctggatga agatgaatta gtgacgattg ggaaagtgat tcaagcaatt tacggagaaa
    10381 aatgtaaatt taactagttc aataatacac aatggattaa ttaatactat caggaaagat
    10441 tgattacaaa gatgtaatga attttttctg atttttgtta atcataaata gaaaatgaat
    10501 ttatctttgt tacacttagg aactagagcg aatgataaat agttctttgg ttactcttat
    10561 cgctgcaaag tacagttcat tttttgttgt tgggaaaatt ttctggattt attgcatatc
    10621 acttcatccg actaaaaatt tttgattccc atagcgaagt tcgtttttgt tccttaggaa
    10681 aaacttgact gatatactag ttttgaaatg acgagtaact ctgtacttca tcaataatca
    10741 agtattgaat tttaattgta tactttttat gcttgaggga tgtctactgt aatacagcta
    10801 ctgcaaaaaa aatcagtaca cttattttct tataaaggat atcaagaact aagctcaatg
    10861 gtatgcatag aaaagaaaaa gccgataaaa tgagattttg atatctcgaa ttatcggctc
    10921 tgcgtctttg cgtctggctc tgtaattaca gttattctaa acttcgttat ttcaattaaa
    10981 atttcttgtc tgcatttagg acaaaataga gggaaatttt ttaattcagt atcttccctc
    11041 atttttaaac gggtcttatt gccacatata gggcacagta tccacctagt atttacaata
    11101 tctatatcct cctgttctaa ttaacaactc aatattcatt ttaaaaattt ctctttagtt
    11161 cactatcaat gtaagttgat tttattaaac atatgcctta ctttgtctat tctattattt
    11221 ggacgacgtg gttggaaagc agacttaatg ttagtaacct gataaccttt taactctgtt
    11281 aaacagacac tgcgtccatt tgtaaagaaa gttaaactgt ttcgatactc ttgaatacaa
    11341 cgggctggaa tttcaccaat gagaatgacc tcgttacctt ttaacttagt atttaaaata
    11401 tttgcacaat atttggaagc atcattatat gctctcgaaa gatattcttg tggtacataa
    11461 atttcgaagc taagatatgg ctctaataac tctgtaccac tctttctaaa agcctgctct
    11521 agtacaatag gcgcaagcat tcggaaatct gctggcgtac tgacagggct gtaatataga
    11581 ccatacttaa aacagatctt acagtctgtt aatttccaac cgtacaatcc ttgttcacac
    11641 ccatagcgta taccttccat aactgcattt tgaaatgatt gatttaaata acctagagaa
    11701 accaggctct catactgaat gccactaccc aaaggaagtg gtgttacaga taaaccaata
    11761 gaagcccaga aaggatttgg aggtacttcg atatcaatgg taaattcaga tttttttaat
    11821 ggtctttcca tataaatgac agttggtttt cttgtttcta tctcaatatg atatttttct
    11881 tgaatcagag tacaagttac ctccatttgg acctcaccta aaaaagatag cacaatttcg
    11941 tgagttactg tatctacata atattgtaga aggggatcac tatcggatat ttcaaaaagt
    12001 gcatctagta acttttctct ttgtactgat ttacatggtt caattgttgt ttgtaacata
    12061 ggaagaggat tctcaagaat ttctctatgt ggtaatcttt ttttatctcc aagtacgtta
    12121 tttagtttta aaagctcatt ttttaaaata ataatctcac caggctctgc cttatctatc
    12181 tggcgtaatt ctccatttat tgaagtatac atttctgtaa cttttatttt ttccttttct
    12241 gatatattga ctgagtctcg caaatgtagc gttccactat aaagacgtac atagacaagc
    12301 cgttgaccat catctgaata ttctacttta aaaacatttc cacaaagttt atctgaattg
    12361 agttgtgtgg gtgaaaataa tttgctagta attacctcta taagttgttt aattccaata
    12421 ttattctttg cacttccgtg ataaacagga tataaggagc aactttgaat tctttcgttt
    12481 tcctcctttt caagttctgc aatattcaat gttttcccaa tggtatattt ttctaataaa
    12541 taatcatttc ccacaattac tgtctcccat tgttctggtt cagtataatc tattacataa
    12601 ggtttcaaat ttagattcac agtctgctta attatgatgt cgtcagaaag tttgtcctta
    12661 atatcttgat aaacatctgg caaatttatt ccattttgat caattttgtt aataaaaaat
    12721 attataggta tgttcatctt tctaagtgca tggaatagta tacgagtttg tgactgtact
    12781 ccatcttttg cagagattag caaaatagct ccatccaaaa cagataatga acggtataca
    12841 tctgccaaaa aatccatgtg tccaggagta tctacaatat ttactttaac attttcccgt
    12901 tgaaaagatg ttattgcggt ctgaatagta atacctctct ggcgttccaa aaacatagta
    12961 tccgttttcg ttgtaccgct atctacactt cctaactctt taattgctcc gctactgtat
    13021 agtaagcttt ctgtcaaagt agtttttcct gcatcaacat gtgctaagat accgatatta
    13081 ataattttca attttatttc ctccattcaa aagctcaaaa agcagaaaaa atcccagtga
    13141 taaatactct tatcactggg attttaatac aaaaatagct gtatactaca cactgatagc
    13201 cacagatgct ttatgataaa atgataaaag tattcttaaa ctgggcacaa aaaaccagtc
    13261 cttattttaa ataaggatgc ttaattaatt attcccgcta tctaattgac agtttattta
    13321 agaatacctt gccgcatttt tattatctcc ttttgaatgt tatcttaatt ctatcatatg
    13381 atagaatgct tgtaaagcca accatatttt ttgaacgaaa gggaaattaa tgagaaatta
    13441 atggaagtta gtgtagtagt tgaagataac tcttcagaat ggctatcaaa attcagcgat
    13501 ttaataacga tttacaagtt cataagggat tctttattca tccagctatt atattacttt
    13561 tcaggtcaat aggacaactg tccacaacct ttctacaaat atattacgta taatttttga
    13621 aatatatact gcttaacaaa atattttgca gtggttccaa tagttttgaa ttgttaatat
    13681 taagtttgac ttggaaaata tcatt
//
LOCUS       DAFELK010000069        13679 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFELK010000069
VERSION     DAFELK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.071"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..902)
                     /locus_tag="LP433_002448"
     CDS             complement(<1..902)
                     /locus_tag="LP433_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBL2006574.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(926..970)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1185..2153
                     /locus_tag="LP433_002449"
     CDS             1185..2153
                     /locus_tag="LP433_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2006575.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2266..2544
                     /locus_tag="LP433_002450"
     CDS             2266..2544
                     /locus_tag="LP433_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL2006576.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2662..2898
                     /gene="secG"
                     /locus_tag="LP433_002451"
     CDS             2662..2898
                     /gene="secG"
                     /locus_tag="LP433_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBL2006577.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3001..3756
                     /locus_tag="LP433_002452"
     CDS             3001..3756
                     /locus_tag="LP433_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2006578.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3759..6116
                     /gene="rnr"
                     /locus_tag="LP433_002453"
     CDS             3759..6116
                     /gene="rnr"
                     /locus_tag="LP433_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBL2006579.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6138..6602
                     /gene="smpB"
                     /locus_tag="LP433_002454"
     CDS             6138..6602
                     /gene="smpB"
                     /locus_tag="LP433_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBL2006580.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6904..7623
                     /gene="atpB"
                     /locus_tag="LP433_002455"
     CDS             6904..7623
                     /gene="atpB"
                     /locus_tag="LP433_002455"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBL2006581.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7676..7891
                     /gene="atpE"
                     /locus_tag="LP433_002456"
     CDS             7676..7891
                     /gene="atpE"
                     /locus_tag="LP433_002456"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBL2006582.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7982..8506
                     /gene="atpF"
                     /locus_tag="LP433_002457"
     CDS             7982..8506
                     /gene="atpF"
                     /locus_tag="LP433_002457"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBL2006583.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8493..9035
                     /locus_tag="LP433_002458"
     CDS             8493..9035
                     /locus_tag="LP433_002458"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBL2006584.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9058..10614
                     /locus_tag="LP433_002459"
     CDS             9058..10614
                     /locus_tag="LP433_002459"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBL2006585.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            10628..11530
                     /locus_tag="LP433_002460"
     CDS             10628..11530
                     /locus_tag="LP433_002460"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBL2006586.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRAVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11553..12959
                     /gene="atpD"
                     /locus_tag="LP433_002461"
     CDS             11553..12959
                     /gene="atpD"
                     /locus_tag="LP433_002461"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBL2006587.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12973..13395
                     /locus_tag="LP433_002462"
     CDS             12973..13395
                     /locus_tag="LP433_002462"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBL2006588.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4521 a         2448 c         2980 g         3730 t
ORIGIN      
        1 ctttcggaaa aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc
       61 caaaattcat aacgatcaac caatgtttgt ccacgactta ttccctgagt ttccacagcg
      121 gtgaagcttt tgaaaccttc acagatggcc ccctcgatga aataagcaac agctaacgga
      181 tcattgatga cacatcctaa aattctttct tgtttccagt ggaagtcaaa ataaaaacga
      241 gtgatcgctt ttaaatactc tccctcttca ggattcattt gacagcagta ttcgaggata
      301 gtcggtgtca agacgatttc tcttgtcaca tctaacccaa ccatttctat cgtttgtttg
      361 agattctcga atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact
      421 ggcgaacagt taccatggct tttgtaagtt ccacccatcg agacaaaacg atccatatgt
      481 ttcccaatat ttgggttgac tttcaaagca aaagcgatat tggtcaaagg acccaaagca
      541 atgactgatg tatttgtctt ttctttgaaa taatcagcca aaaaatcaac ggcatggaga
      601 ggttctgcct gttttctcaa gatcatcggg aaatttgttt cccctaaacc atccatacca
      661 tgagtgtctt gtgcactgat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca
      721 ggaatgtcta aacgatcaca gcgttccagg catttcagca cattctgcgt acctatatct
      781 gcagggacat tcccacaaac tacggtaata gcaactactt cgatatcagg ggatttgaca
      841 gctaatgata aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tacttttcgc
      901 attatttcca atctcctttc tttagagata cttagttttt tattctggga agtttccgaa
      961 ccagtccaag acgagcgtct tgattataat gcacgaaatt agtatactgg cttttattgc
     1021 gaatgtaaat gctctcttac aagtaaatct attgaggaga actttaagta aatgatacaa
     1081 tgaaaaagaa atggaattta cgtgtgccga aaataaagaa tcctatggat cggtacattg
     1141 gataatagat agattatagt ttggcagaaa gcggcgggtg tacaatggtt attttttatt
     1201 tcattcttat tctgataatt atagggatca gttaccattt tctttcttat ttttatgcaa
     1261 agaaattagt aagagcggga gtacagagag gatatgactg gtatgaagac actggtcatc
     1321 gtttgatgga ccctgctgca gtcacgtcag tagaaaaaaa acgacaaaaa ttagaagaag
     1381 agtgtgaaag cttttgggag cagggaacac ccaaaacaat caaaagttat gacgggttga
     1441 aactagctgg tcagatgttc atccatccaa ataagcagaa taaatgggtc atttgcgtac
     1501 atgattaccg aagcacaggg aaaagagaca tgtctcatat aggtaaaaga tatgcagaga
     1561 aaggattcaa cgttcttgta cctgatttac gtgcgcacgg agaaagtgaa ggagaaatca
     1621 tcggaatggg atggctagat cggctagatt taattgcctg gatccaactc atcttagatg
     1681 aacagccgaa tgcgtccatt attttacacg gcggatcaat gggagcttct acgatcatga
     1741 tggcaagtgg tgaaaaactt ccatcagcgg tcaaaggatt tattttagac agcggatatg
     1801 tttctgttta tgcagaattc cgatatatgt taagtaaaat cactgtcttt cctaaaaaaa
     1861 tggtcatgag atatgcgaat cattatgccc agaaatacgc cggttactcc ttaaagcaag
     1921 catcagctac gagacagctt ggcagcaacc atctgccttt attagtcatc catggtgaaa
     1981 gagatcattt tgtccctaca gaagcagcgt acacgattca aaatgctacg gcaggggata
     2041 aagcactgct gcttgttcca gaagcagaac acttggaagc atcgatgaaa gatccgaaaa
     2101 cctattggac agtgattttt tcatttattg aacaaagaat aacgatggat taattttctc
     2161 ttcttttttg taagtaattc gaggataaat aattgtttat agatctggag actgctaaaa
     2221 taaggtagga ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagaa
     2281 gaaaaaaatc gtcttgcttt attcaatgat gagcaacaag agattggaga aatgacatgg
     2341 tcagatgcgg gcccagacat catgatcatt gaccatacat ttgtagatcc agcatatcgt
     2401 ggtcaaaagt tagctgaaaa gctagtgtat actggagtag aattagcaag acgagacggg
     2461 aaaaagatca ttcctttatg cccttatgca aaaaaagagt ttgaaaagaa accagaatat
     2521 caagacgtct tacgtcagtc ataagaataa cagctgaaag ttttgaactt tcagctgtta
     2581 ttccatttat atagagttgt cacggacttt tatctatgat aaagttaaag agacgatatc
     2641 ttttgggaag gaggctgcga tatgtataat ttaattttgg gaatcgtgat cgttttatcg
     2701 attgttatgg tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca
     2761 tttaccggcg gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc
     2821 atgcagcgat caactgcagt tatgggagct atctggatga tcttattatt tgtcctagca
     2881 tatttatctt cgaagtagtt gaataagcct ctcgcaaaac ggcgggcggc tttttttatt
     2941 gcaaagagaa cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag
     3001 gtgagacgag tgagacaatt accaaaaccc ctttatgcaa aacatggaaa gcgagcggtt
     3061 ttgctgcttc acgcttactc aggaagtcca aacgatgttc gaatgctcgc acgatttttg
     3121 gaaaaagcag attatacagt ttatgcgccg ctttttaaag gacacggaac aatggagcca
     3181 tatgatatct tgcaagaaaa agcagaaagc tggtgggcag acactaaaaa agccatccat
     3241 tttttacagt ctgagcagtt ttctgatatt gccgtattag gattatcaat gggcggcatc
     3301 tttgctgtac gagcactaga agaagaatca gtgattggcg gcggtttttt ctgttcgcct
     3361 ttgtctcctg taaaaacaaa cgtgcctgaa aactttgaaa aatacgtacg tcaagtgctg
     3421 aagacagcag gtaaatcaga gaaagaaatc aatgaaaaag cagttgctta ccgctcgtta
     3481 gctgaacaac aattaatgga tatacaagat caggcagcaa tcgtagaaag taggttgtca
     3541 gatatccaac agccgatatt tttagctcaa gctgggaaag atgaaatgat cgaccctaat
     3601 ggcgtatttg aaactgcacg caagttgagc cgtcagcgag tgacacttca atggtatcct
     3661 gaaagtggtc atgtgattac agttggtaca gcaagacgcg aattagaaaa agacgtcttg
     3721 gaatttttag aaaaattacc ttggaatgag gaataaatat gacaaaagaa acgataaaag
     3781 agaaaattct ctttttcatg gaaagcagtc gcaaacgcag tttttctatg gaagaaatcg
     3841 ctgaaggttt agggttccaa aaaagcgatg attttaaatt actagtacaa acgattgctc
     3901 aaatggaaag agaacagagt atagttttca ataaaaaagg aaaagtgaaa cttcctttaa
     3961 aaccaatctt gatcgaagga acatttcgag caaatgaacg aggatttgga tttgtaacga
     4021 ttgatcccga agaagatgac atctatatcc caaaagaagc gactggtttt gcaatggatg
     4081 gagacaccgt agcaatcgat atcatgaagc gagcaaatac agatatggat cgcggagcag
     4141 aggggaaagt agtcgagatt cgagaccggg cgactactca gttagcaggg gaattcgttg
     4201 cttattcaga agaagaaata caagaaacag atctttacgg cgttgttatc ccgaaagata
     4261 gaaagctcaa ccaatttaaa gtatatgcag cagcagaggg agttcgtcca gttgacggaa
     4321 gtattgtgct gatcgaactg acccattacc ctgaaaaagg gtatgcgact agtttagaag
     4381 ggataatcaa gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcaattg
     4441 tcgtggctaa tggtatccct acgaaatttc ctgatgatgt attgtctgaa gcagatgaag
     4501 ttccagatca aatcagcgaa aaggatataa ctggacgtag agatttaaga aatcagctca
     4561 ttgttacgat tgatggagaa gatgcaaaag atctagatga tgcagttacg gttaaaaaat
     4621 tagataacgg taattatttt cttggagtac acattgcaga tgtttcttac tatgtgacac
     4681 aaggcagtca attggacaga gaagcatatg aaagagggac aagtgtatat ttgactgatc
     4741 gagtgattcc gatgatcccg caacgtttat cgaatggtat ctgttcactg aatccccatg
     4801 ttccaaggct gaccatgagt tgcgaaatgg agattgatcc aaatggacaa gtagtctctc
     4861 atgatatttt cccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc
     4921 aaatcttaga agatcaagac gaagaaacga tgcaacgcta tgctcagctc gtacctatgt
     4981 tccaagaaat gggtgaattg catcgaatcc ttgaaacgat gcgaatcaaa cgtggcgcga
     5041 tttcttttga ggatcgcgaa gcgaaaatcc ttgttgatgc tgaaggacac ccaaatgaca
     5101 tccagctaag aagcagagga attggtgaac gcttgatcga atctttcatg cttgcggcca
     5161 atgaaacggt agctgaacat tataataaat taaatctgcc gtttatttac cgaatccatg
     5221 aacagccaaa agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc
     5281 tggtccgagg aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag
     5341 tagaagacaa accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag
     5401 cacgctattc agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact
     5461 ttacatctcc tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca
     5521 gtgaagataa aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag
     5581 atcatagttc taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga
     5641 agaaagcaga attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg
     5701 ttgtgaaatt cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca
     5761 atgaattgaa acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa
     5821 gaactggtct gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc
     5881 cagatgaacg agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac
     5941 gtccaaaagc acgcaatgga aaatctggaa aacgagaagg aaaacaagca ggcaaacgct
     6001 cagaaaaaaa tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga
     6061 aaaaagggaa aaagccattt tacaaagatg tcaaaaagaa gaaaaagaaa aaataaaatg
     6121 agttggagga aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag
     6181 ctcgccatga ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg
     6241 agatcaagtc gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca
     6301 acggggaagc tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta
     6361 atcatgatcc gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg
     6421 aaaacgaatt gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg
     6481 gctatgccaa ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag
     6541 atttgaaacg aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat
     6601 aatttcatta tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg
     6661 ttagcattta atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg
     6721 tgcatgggga aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga
     6781 aaatgttttg aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg
     6841 aaaaaaccag atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat
     6901 ggattggatg aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt
     6961 tgtataatgg tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga
     7021 aatcttaagt tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt
     7081 cgaggaatcg taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca
     7141 tttacattgt ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc
     7201 ttacctaacg aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact
     7261 ttggcattta taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa
     7321 ggatatttcg taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt
     7381 gaagaattta caaatttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg
     7441 gaagttttgc taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca
     7501 ttagcaattc cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa
     7561 gcatttgtct ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa
     7621 taatactcgg ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa
     7681 ttatatcgca gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg
     7741 tcaagttatc tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt
     7801 ccgtacaaca atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt
     7861 tatcgccttg attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat
     7921 cgtttgttac tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc
     7981 tatgctgaat caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt
     8041 tgtcagcggc tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat
     8101 cagcgatatt ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca
     8161 atctcgcatc aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg
     8221 ttctgatgca gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa
     8281 tattttgaag gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat
     8341 cactgtagaa cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct
     8401 tcaaatcgcg gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat
     8461 caatcaatac attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa
     8521 gacgttacgg gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct
     8581 atcaagatct cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt
     8641 taagtgatgt tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg
     8701 gttatgatgg gatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg
     8761 accttttgtt catgatcgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat
     8821 tgggaagtgt cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga
     8881 atgttgcaaa aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta
     8941 ttattggtgg cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc
     9001 aattagaaaa aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg
     9061 gccatcaaag cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac
     9121 gtgctttcag tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca
     9181 catggtttag aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga
     9241 atggcgcaaa acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc
     9301 attcgtgaag gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag
     9361 gccttgatcg gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc
     9421 gttactgaca aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct
     9481 gttaacgaac caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc
     9541 ggacaacgtg aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgatcgat
     9601 acgatcatca accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa
     9661 gattctacag ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca
     9721 atcgttgtga atgccggtgc gtctcaacca gcaccattgc tttatatcgc accatatgct
     9781 ggtactgcaa tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat
     9841 gatctttcaa aacaagctgt tgcttatcgt gaactttcct tgctacttcg ccgtccacca
     9901 ggtcgtgaag cttatcctgg ggatgttttc tacttgcact cacgtttatt agaacgtgca
     9961 gcaaaattaa gtgatgattt aggtggcggt tcaatgactg ccttaccatt tgttgaaaca
    10021 caagctggag atatctctgc ttatatccca acaaacgtta tttcgatcac tgatggacaa
    10081 atcttcttag aaagcgactt gttctacgca ggtactcgtc cagcggttga tgccggacta
    10141 tctgtatctc gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact
    10201 ttacgcctag acttagcaag ttaccgtgaa ttagaagcat ttacacaatt cggttctgac
    10261 ttggatgcag caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa
    10321 caaaaattgc atgcaccgct agctgttgaa aaacaagtag tgattttgta tgctttgaca
    10381 catggattct tagatagtat ccctgtagac agtattttag acttcgaaca tgaattattc
    10441 gaatatctgg ataccaatca ttcagatatc tttgaaacaa tccgtacaac aaaagatctt
    10501 ccagaagaag aagcgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca
    10561 aaaggaagta attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt
    10621 gagatgaatg ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac
    10681 gagccaaatc acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc
    10741 ttcttcacag aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac
    10801 tgctactcag ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag
    10861 catgctgctc agccgtgctg tgaagaaaac tggttatatc gtcatcactg cagatggcgg
    10921 tttagtcggt ggatataaca gctcgatatt gaaacaaacg atgtctattt tagaagaaga
    10981 ccaccaatca cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt
    11041 taaagcacgc ggtatcaatc tagcatatga gctgcgcaat ctatctgatc agccaagctt
    11101 tgatgaagtc cgcaaaatcg taaatatggc aacaactatg ttccaaaacg aagtattcga
    11161 tgaattatac gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga
    11221 aaaaatgctg ccaatctcag acttagatcc agaagaagca acgactttcg aacaagaata
    11281 tatttttgaa ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag
    11341 tttgatctac ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc
    11401 aatgaaaaca gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttataa
    11461 ccgtgcaaga caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc
    11521 actagaatag tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa
    11581 tcggtcccgt tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg
    11641 cattagttgt ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag
    11701 aattagggga cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag
    11761 gaatggaagt cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag
    11821 gtcgcgtatt caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg
    11881 cggaaagaag cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag
    11941 aaattttgga aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga
    12001 aagtcggact attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc
    12061 ataatatcgc ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc
    12121 gtgaaggtaa tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca
    12181 tggtgttcgg acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt
    12241 tgacgattgc ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca
    12301 acattttccg tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt
    12361 ctgcggttgg ttatcaacca acattggcaa cagaaatggg tcaattacaa gaacgtatca
    12421 catctacgaa aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact
    12481 acactgaccc ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac
    12541 gtaaattaac agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg
    12601 ctttagcacc tgaaatcgtg ggggaagaac attataaagt agcaacagaa gtccaacacg
    12661 tattgcaacg atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat
    12721 ccgatcaaga aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa
    12781 actttaacgt ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa
    12841 cagtgaaagg attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt
    12901 tccgaagtgt tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga
    12961 aaggggtgcc ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc
    13021 tatgatcacc atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg
    13081 cctaaacatg caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca
    13141 gattcagata cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat
    13201 aatgttgttt caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt
    13261 gcggaacgtg caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat
    13321 acgaacgaat tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta
    13381 tctaagcact cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag
    13441 gttatgacag aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca
    13501 aatttttgtg aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatca
    13561 gaggttgtaa aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct
    13621 catattttgc cgttttttga gctaataccg agggtcagat gattgaacac cgtttattt
//
LOCUS       DAFELK010000070        13346 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFELK010000070
VERSION     DAFELK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.072"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(45..1364)
                     /locus_tag="LP433_002463"
     CDS             complement(45..1364)
                     /locus_tag="LP433_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2006589.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="LP433_002464"
     CDS             complement(1361..2014)
                     /locus_tag="LP433_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2006590.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="LP433_002465"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="LP433_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="LP433_002466"
     CDS             complement(2724..3440)
                     /locus_tag="LP433_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBL2006591.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3490..3699)
                     /locus_tag="LP433_002467"
     CDS             complement(3490..3699)
                     /locus_tag="LP433_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006592.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            3976..5249
                     /locus_tag="LP433_002468"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="LP433_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="LP433_002469"
     CDS             complement(5356..6387)
                     /locus_tag="LP433_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006593.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="LP433_002470"
     CDS             complement(6394..7224)
                     /locus_tag="LP433_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2006594.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="LP433_002471"
     CDS             complement(7221..8036)
                     /locus_tag="LP433_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2006595.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="LP433_002472"
     CDS             complement(8033..8857)
                     /locus_tag="LP433_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBL2006596.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="LP433_002473"
     CDS             complement(8847..9947)
                     /locus_tag="LP433_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2006597.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="LP433_002474"
     CDS             10125..10910
                     /locus_tag="LP433_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBL2006598.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="LP433_002475"
     CDS             10943..11326
                     /locus_tag="LP433_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL2006599.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="LP433_002476"
     CDS             11402..11533
                     /locus_tag="LP433_002476"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2006600.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="LP433_002477"
     CDS             11502..11738
                     /locus_tag="LP433_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2006601.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11816..12787)
                     /locus_tag="LP433_002478"
     CDS             complement(11816..12787)
                     /locus_tag="LP433_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBL2006602.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4055 a         2912 c         2306 g         4073 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atggcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagccgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttat
//
LOCUS       DAFELK010000071        13299 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFELK010000071
VERSION     DAFELK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.073"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..430
                     /locus_tag="LP433_002479"
     CDS             <1..430
                     /locus_tag="LP433_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006603.1"
                     /translation="DENGQFFVWMRHEHCWCNPFVLKKENEIRTKIANGEWDYLFRWE
                     DESFIANDMDHAFVSFLDNTWGTWYDCYLEKLGFQNIDIDAIECLKEVDQKYEEEPYY
                     LLQQKLANNSVFQVEIWENEDGTYEGLAQEIPFSDRKSSI"
     gene            605..940
                     /locus_tag="LP433_002480"
     CDS             605..940
                     /locus_tag="LP433_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006604.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(1197..2780)
                     /locus_tag="LP433_002481"
     CDS             complement(1197..2780)
                     /locus_tag="LP433_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006605.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRNRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            2902..3486
                     /locus_tag="LP433_002482"
     CDS             2902..3486
                     /locus_tag="LP433_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006606.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            3497..3742
                     /locus_tag="LP433_002483"
     CDS             3497..3742
                     /locus_tag="LP433_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006607.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            3748..4470
                     /locus_tag="LP433_002484"
     CDS             3748..4470
                     /locus_tag="LP433_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006608.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            4601..5344
                     /locus_tag="LP433_002485"
     CDS             4601..5344
                     /locus_tag="LP433_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006609.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            5350..5715
                     /locus_tag="LP433_002486"
     CDS             5350..5715
                     /locus_tag="LP433_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006610.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            5731..6261
                     /locus_tag="LP433_002487"
     CDS             5731..6261
                     /locus_tag="LP433_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006611.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            6423..6653
                     /locus_tag="LP433_002488"
     CDS             6423..6653
                     /locus_tag="LP433_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006612.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVRLPVSELKK"
     gene            complement(6857..7336)
                     /locus_tag="LP433_002489"
     CDS             complement(6857..7336)
                     /locus_tag="LP433_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006613.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            7456..8793
                     /locus_tag="LP433_002490"
     CDS             7456..8793
                     /locus_tag="LP433_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBL2006614.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            8816..9343
                     /locus_tag="LP433_002491"
     CDS             8816..9343
                     /locus_tag="LP433_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006615.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            9330..9893
                     /locus_tag="LP433_002492"
     CDS             9330..9893
                     /locus_tag="LP433_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006616.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            10316..11053
                     /locus_tag="LP433_002493"
     CDS             10316..11053
                     /locus_tag="LP433_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006617.1"
                     /translation="MADRKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANHQD
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(11070..11486)
                     /locus_tag="LP433_002494"
     CDS             complement(11070..11486)
                     /locus_tag="LP433_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006618.1"
                     /translation="MNKKRKLSVLITLVSILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETVTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            11878..13125
                     /locus_tag="LP433_002495"
     CDS             11878..13125
                     /locus_tag="LP433_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL2006619.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETAKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTETDTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
BASE COUNT         4814 a         1794 c         2533 g         4158 t
ORIGIN      
        1 agatgagaat ggacaatttt ttgtttggat gcgacatgag cattgttggt gtaatccttt
       61 tgtgttaaaa aaagaaaatg aaatcagaac taaaattgca aatggtgagt gggattacct
      121 cttcagatgg gaagatgaat cttttatagc aaatgatatg gatcatgcat ttgtctcatt
      181 tctggataat acatggggta cttggtacga ttgttaccta gaaaaattgg gctttcaaaa
      241 tattgatatt gatgctattg aatgtcttaa agaagtcgat caaaagtatg aagaagaacc
      301 ctattatctc ttgcaacaaa aattagccaa taattcagtg tttcaggtag aaatttggga
      361 aaatgaagat ggaacttatg aggggctagc gcaagaaata cccttctcag ataggaagag
      421 ttcgatttga aaagagtata tcagcaattt ttatgaagtg aaagcaagct tacaatatag
      481 taatggaaaa ttgtggttag ctggaaggta tattccagct aaccaaatct tacgttttct
      541 gggagagtgg cgttttaaaa caatttccta ggaaaaatag ttaacataaa aggaatgaat
      601 tgttatgaaa caatatttaa atgaatggaa agcgatagag gggtcattag taacgcaaag
      661 aataaaggaa ttacctgatt gcttagagaa ggatcatttg tttcaaatac gagaaatgtt
      721 gaaaaaagaa cagtttgatc cagaccaatt tttagtagtc gagtatccaa ctattggagt
      781 gtactgttgt aaccatatca atgatggaaa atattttatt attcaggagt atggaggaca
      841 gttaactcct ttctatacta catgggaaat gagtgaagaa ggaatcaata attttccatg
      901 tgaaagcatc gaagattcaa tttcacacac cgaatgttaa ttgattataa ctataaaaaa
      961 ggattgaaca ttatgttcaa tccttttttc aatgaaatgt tttccgccat ttcattgttt
     1021 ggtgcgattt ctattttatt atatcaaaat aaagagagat tctaaagaaa gaagagggaa
     1081 atatataaat caagcgacag tatatttatt attaaatgct attgtgagaa tataactaat
     1141 tagtttaatt tgaaagtaaa tatacgctat aaaagtgcat cttgtgttat aaaaaattat
     1201 tttattttgt gaacataatt taacaattct ttctcggaat tgatttcttt tcttaaatag
     1261 tcttcagact tattaataat attatctatt atgtctagat acatatcact tttcgattca
     1321 gctaattcat acagtttttt taattcttta tcctttaatt gaaaaccctg atccatagtc
     1381 actgcatttg gatatagaag cccactataa tgtttacgta aattcacttg gaatttctga
     1441 ttataaaagt ctaacagatt agaaataaaa ggcggaaaat tactgttttt gtaaaattga
     1501 ttatttccat ttaggttgta tagtaatttg ttaaattgct cctgatttaa tttattgtaa
     1561 atccatggta atacttccat atccttatct gctaacctga atgaactagc atcggtaaga
     1621 tgttcgatca taaaatctat gaacatctct ttttcaccaa aatataaata ttgattatat
     1681 attgtttcta atgttgaaga tggtagcgaa gaaactctca ttttttgctg gagtatagga
     1741 tcaactagac tatttaagtg attttgtaat tcttcattgt tgtttcctag aactgcaagg
     1801 gaacgtaaac ggtagtaata ttctatttct gttagtactt gttgtttcgg tttaaaatca
     1861 tttattgata tttgtaaatt ttgaattgtc tcgtctgaaa aatcatgttg taattctgga
     1921 tgggtagcta taaaagtaag taaaaagaac ccttttgtat acgtgatctg ttgattttca
     1981 ccaagtgatt tattaatttc ctctcttgat tcagctgtga acctatactt tgcaatttct
     2041 ttttttagaa tatttaaata gaattcttta ttatcaaaaa ttagggcatt aagtagtctg
     2101 aaagtacttt ccctatttct atctgcttcc tcatttccat aagataattg aaaaacaaac
     2161 ttaaaggctg tcttacatag gttttctttg gctttttcgc ttagtttatt tagatagcta
     2221 ttttttagtg cagagtgaaa ttcttcaggt gtaacagaca tagcatgtat gcgacttgca
     2281 tattgtataa tttcgatcgt tacttttttt cctaatattg gattttttag gaatataatt
     2341 tcataggact tccgtataac atcctgacaa gtttcttttg ttatatctct taattcccaa
     2401 gtattaccgt tgtaagtgac tacaggatga gctgaataat ttctttgatc cttaatatat
     2461 tttaaatcct catattcata gctatcaatt agctcagttg aactataagc tttttctagt
     2521 agttccattt cccattttgg agagtttgga tcactttttc ttagtctagc tatatcttct
     2581 aaaattttct tagaagtatt atcctcgtaa atatttgcta aatcagataa tttatcaatt
     2641 aaatctaaaa taagcgcact gtaattgaca gctattgcag aacgataatt tccctgataa
     2701 aaactacttc taacttcttc taataatgga ataattctag gatttttaac tttttttatt
     2761 tcatcatcta atataaacat ataaatctcc tttttttatt tgtatgacaa gtttaccata
     2821 aaaaaaaatt aaaaagcgag acatatttat gttgttgtgt tatcataata acataaatat
     2881 gtagagtgag atgatgaaaa aatggatttg aaacaatcgt tttacatctg gttatatcct
     2941 gataatccta tgtcaataat ggctgatatt tttgtagtta gcatcttatt gtatttattt
     3001 tatctaattt tctttcacaa tttaatcggg tacatgattc ttgattggaa aggaatgttc
     3061 gatatagaaa gaaaaccatt tgctaacaat caaacctata ccgtcttcga aagtggagat
     3121 tgggaagaaa atgaagttga tgtgatccat gaaattggat tagctttatc aggaatacaa
     3181 gatgctgatg ttttggtatc aatgacaacg gatactggat acaacgctta tgaggtattt
     3241 tatcttatgt attttatatg gcgtgatggt caagaaatta tcaatggtcg tgctgaaaaa
     3301 acaatcaatt ctaatactga aatttctttt tgtatgggtg aaggggaaat gattgtatat
     3361 aaagatgggt cagcaaacat taaaacagcc tttggtgata ttgaaacaag tattaaggaa
     3421 cttagggaat atgtgcagaa cccatataat tttcaatatt tagcaggaag aataaattta
     3481 gtttaggagt aaaaatatga aaaaaattat aaatcaacca acaaatcact tgataattga
     3541 aggtgttatt ttcgtaacaa tgtattttac tgtaggaaat ggcatctcaa atacaatcat
     3601 tcaaaaaaat ccacaatacc tattatttag tctttatgct tggattgtac aaatggtttg
     3661 ggtttccata ttgatgctgt tgttttattg gatagtacgg gttattcttt tattgttaaa
     3721 caaaagaaaa aaggataggt gaataaaatg aaatcaacta aattgaaggt tgtattgtta
     3781 tcgacagcag cattaataac ccttacagca tgtggtacaa ctaatagtgc taataataac
     3841 aaagacacaa agtctagtag tacgatggtt actaaaaaca gcactacatc ggcatcaaca
     3901 acaatgtctt caatgactga aaataatgct gaaaagtatc aaaaatacga agacattaat
     3961 aaaggtcaaa agccggatga agtttataac aactttatta atacagtaaa aaatgatgaa
     4021 aattatggga atgatccatt gcaaaataaa aatctgacta tcgttcttta caaacctgat
     4081 tgtccagatt gtcaaaaagc agaatcaaaa atcatgcaag aaataaaaga aggatttagt
     4141 tatgctccaa cattaatgca tgatattacc ataaataaac cagcttacga gtattacgca
     4201 gttgctgtag atattactga tggtgtacct gagtgggtac aaaacattcc tggtctggct
     4261 gatgagaaca atcaatatca tacgccaaca gttgcagtag taacaccaaa gaaagttaac
     4321 ggcacactat actgggatgt aatgggaatg acaacaaata caactgatga aatgattgaa
     4381 agtacaacta aatattatat ggatttggga gcatataaat tatatcaaca atcagagcct
     4441 gttatggacg atcaatccaa agttaaatag atctttaggg cgtaagccct atttttttaa
     4501 aattaagtga taacaaataa atgatttctg aaacaaacgt tcttactcaa ctactcgaaa
     4561 cacacaagct aattaactag attataaagg agaatgcgta atgaaagaaa tcagtgcaaa
     4621 tgaagctcat attccgcaaa agaatcaggt tggtatatat aaggtgcttc atggtgaagg
     4681 aatttataaa atacagttac ttaccggtta caataatggt gcaaatggga agtggttaaa
     4741 ggcaacaagt attcgtgaac ttagaagtga agtagaaaaa attaggcttg gtctcacaag
     4801 tgaagaaata gctaaactga agggaaataa ttcttttgta attgaaaaag aaaaggaaaa
     4861 acatctactt tatcgtgagc tgaaaattga agaatactat gaaattgatt tacctgaaaa
     4921 attaagaatt attgatcaac gttcagaaga aaaatggaaa actgaaatat atccaagctt
     4981 aaatgactac aagacatcag gaaagcccat gtataactac acaggctttt taacctacac
     5041 acaatacaaa tatgcctttc gcaaattaaa aggcattaaa caagctgaaa ttgctctgta
     5101 tgagatgaaa aaagtggata gattgaaatt gattcaagat ttagtgcaaa atacatggaa
     5161 tcaagcgatt gtcgagctag aaaaagaaaa tgggaaaatt ttaactaata aatatctgat
     5221 cgtaaatgaa attgaagaat taattggttt attttcatgt gaaaaaggtg aagtcttctt
     5281 gaagtcatca ccaacctatt caattttgga cagtccgtat cagtttatac aggcaaggag
     5341 atgagttaga tgtctagctt gaaagatgac tatatccaag caaaacaaga gtatgaaaaa
     5401 atacagatgt tgaaatctga gaaagtcgaa ttatttttaa cacaaaaatt agcagaggat
     5461 catattgcta acttagatgc taaaacttta gaggaatatg atcggcagtt taatcagata
     5521 catcacaata tcattttgct tgttgagcag gcaaagcgaa ggtttgaaaa agcggaatat
     5581 gatctattag atcaaggaat tgtatgcttg gataagggat tgcgaagata ttatggtgca
     5641 gagttaaaaa agcaaaatgt agatagaaat gcactaaaac atgaaatctt agaattgata
     5701 atgcaacgaa tttgaaggga tagaaagcaa atgtcacaaa acattagtgc tgtaaaacaa
     5761 ttaatagaag aagatttaga gaccacagtt cagagattag cggaacgaat ccattttgca
     5821 aattatcaaa ccatctctaa ctggtcaagc aggaacagaa atccggaaga aattccaatg
     5881 aaattttttt atcgaatcgg aaaagaatat ggtgttgatc cgataaaaat tttcgagaag
     5941 accatgattt attactatca tggaacacct aacgaagtgt tagaacatct tttggaagag
     6001 gcaaaagaaa aatcatcaat attagagcta tcgcaaaatg acaaagttat tcaagtgaaa
     6061 tgcgttgatc caacaggaaa gattattgtc ggttttgata ttgaaagaaa atccaaaata
     6121 gattttatta cacaattaaa aaagataaat aatttagata ttctaacgct tagaccagat
     6181 catgaacagt tgtttatgag ttttaaaaaa caattgaaag aaatacaaaa aagatataac
     6241 aaggtgtttc ctaatgcgtg aaaagctcaa agaaatcaga gttttttgga taattaacaa
     6301 agaatgtatc atcttatata ctcttggatt tcttagcatg atcttgtttt ggtggttata
     6361 tttaaaacag taattggaga gggtcaagag gatttttatc aagataagga tgtggaaact
     6421 gcatgtggaa taatagatta aaaacaggat tgttattaat agttatttcc tgcgctatga
     6481 tgattggtat gaggatacaa agggaacaat cctattttga agtttctgct aacaacgtaa
     6541 tagaaaaatg ctattacggt caacattatt ggagtgagga agtcagagaa aatatagatc
     6601 gtgaatatgt tcaaagaatt gttagattac cagtaagtga actaaaaaaa tgatgagatt
     6661 atcagcatat cttttaatgt ttttgaatgt ggtcacgtta atctttgtag taatcggtgt
     6721 gactttcgat ttaatggaat agtgggaaat ctataatgga aaaaagagac acgaatgaac
     6781 atattttttg aatcaatatt gttgatggtt tttgcgatca gcgcttacca gaaatctaaa
     6841 aaagagtaat gattgtttaa tcatcactct ttttttgtag ggaaattgaa atatgtggag
     6901 cttgtattgg tttagttagg attgcttggc tataaggagc tagttcttta tcaaaaccat
     6961 caaagtaggt tttcagtagc gatttaactg atcgctcatc ttgtttgatt tggataattt
     7021 cagcatccaa atcggttgtg agatcaggag cttttgatgc gattacctga ttttttttat
     7081 cttccaactc tcttaggctg tttaacaagt tgtaaaaaga atcattttga ttgttcattc
     7141 caacgtgagt tgcaatttta acagaagttt cgtccgtatt gtcatcaaaa gaactcattg
     7201 gaatatcaag tagtaacgag gatgtttctt ttactgactt tttctttaca gcattttttg
     7261 tttttccatc ttttttgctc tttactcgag atgtttttgg agctagttta ggtaaatcac
     7321 ttgttttatc agtcatttat tagcttttcc tttctattaa tttatgttat tatattatca
     7381 taataacata aaaaagtaca ctttttgggg gcgtagttat tgaaaaaatc taagagaaag
     7441 attgccacat tgcttatgtt aatggtgcaa tttacaggga ttgcaatgag tgtaatcaca
     7501 ataaatccgc aagtgataca tgctgatggg atagctactt atgatgcaca atttaactgt
     7561 actactgaag gtagtgggtc aggaacagat agcgatggaa acgatactgg aagtggcgct
     7621 gtaacaggtg atgtagccaa aaatattgaa gatatttaca aatacatgaa tggagaatat
     7681 ggcttatcag gtgctagtat tgcaggtatt ttaggtaact ggaaacaaga atcaggtatt
     7741 gatcctcgag cagtagaagg gtattacgga gatggacaga gagaagttga cttcatcaaa
     7801 caatttactg atggtctgat gggtattggc tatggtcaat ggacagctgg gcgacataca
     7861 gcattagttg attggtctaa gaaaaataat ggcggttctt ggtggactac agaagcccaa
     7921 ttggacttta tgttcaaagg tgatggggga ttcgtaggaa tattaaaaga ttatgcttta
     7981 aatgcttctg atgatgtcgt agaaaatgca gtaacttttc ataaaaactg ggaaatttca
     8041 gctgattccg aatcagctgt aatagctgta cgtggtgaaa atgcaaaaga aatctggaag
     8101 tacatgaaaa gcaagggtat ggacggtgca aaagatgaaa gtaagatcaa taaaatatcc
     8161 ggaggttcaa gtaccggaga tggatcgaat aattcatcaa gttcagcatc aggaacagta
     8221 gaagatgcct gtgcaactac ggatgacgct aattctggtt ctggatcaat tgggaaagaa
     8281 ggaaaaatta acggtaaaaa aggtcaagta atagcgaata tgacttatga agaagctttg
     8341 aaaaaatatg ggaaagcgat cacgctacca aaattcaaag aaccagattg gtcaacttca
     8401 ccttttaacg gaatatatca aggtcagtgt acagagttga cgtgggctta tatgagccaa
     8461 ttatacgatg ggaatcaacc gactactgga aatggtggtt atgtatggga aagctacaaa
     8521 tcggcaggag caaaaataac gaacaaacca atcgtaggtt atgggtttag tgcttcagat
     8581 ggatggttat gggctgttgg cgatgcaggg catactggtg tagttatagc ggtgtttgaa
     8641 gatgggtcat ttctatgtgc taactttaat gttccaccaa cccaagctcc aacaagggga
     8701 gtttcggtaa ctttgattga tggagtggac ggatcagata atgtgcattt ctttagcggt
     8761 gtaggaaaag ctaaatttga aatcgaaaaa taaattggaa tgaaggacga tatagatgaa
     8821 tagtaaagtg aaagatacaa ttatcatttc tttgctttct ggtatgttat tagcactgct
     8881 tgttggaatc ctattcttca ataagcagaa tcaggacata gaagctgaaa aacacagtgt
     8941 gcatattgaa gataagctga cattctttaa agaggttaaa ccaaatgagg tggatggatt
     9001 acggaaagat ttagaaaatg atattcaaga aatgttgaat ggatcagttc aaaataagtt
     9061 tgcagatcaa tcaggtgaag aatttttgag aaaactattt attgtaacag gtaaaccacc
     9121 aattactgat aagagtagtg agaaagaaaa aatcgagtac tataagcctt ttacttttaa
     9181 gctaacaaac tttggaatta agacatctag tagtgggttg tatgaagcat tgaccgattt
     9241 tgaagttcaa tacaatggaa aaaaagtgta tgataccaca ttaaccatca cactaaataa
     9301 tgataagaaa gtgactgggg gtgcttttta tgcaaaatca tgaaatcact actgctaaaa
     9361 aggcgatcgg aatactttcc ataattgtga tcctttgttg tgtggtacta tttcaaaaga
     9421 aaaatgctta tgataataat gtcaaagaat tggaagacct taaaagtaaa caaatcgaag
     9481 tagtcaagaa taaccagaaa gtgaaagcta tgcaggaagc tcaatacaaa gaattgggga
     9541 atgctgaaat caaggaacaa agtaggaaat tctttaattt attttacaac tggaattcat
     9601 gggaaaaata tacgaagaat atgaaggaaa tacaaaaaga atttcctcag atagtaaagt
     9661 ctagtcctgt tgatatttct ggcacgatgg taggcactgg taatagtcca atatctagct
     9721 atactgctga ttactataca acaaatcaaa aaggtaaaat ggttgaattg attacacaga
     9781 caagaaatac tccaacaaca gcaacaacaa caatttggcg tggagtaaca agcataggag
     9841 aaaatcaatt gttttacttg gaggatttag atagctatgt aagagcggag taaaataaaa
     9901 aaagagctaa cggtaccaac gttagctctt tgtgctgacg atgataacaa aacctaccga
     9961 aaaaggattg tttcatcaca aacacaaaca gaaaagaatt gataaaaaac ccgaacctca
    10021 gaatttttat taatcaattc atttagatta taataaattg agctgaacat tacaatacgt
    10081 atatgttgta aaacgtaaaa aaagtcaaaa gtaaatactt tcttaaaaag tcaaataaaa
    10141 ctattaaaga caatatatat ggtttatttg acataagaaa atggtctaga tgataattgt
    10201 aatatagaat tgtaggctta aataaagcat aaaatacctt ttatgataag gtatagctct
    10261 taattttaag cagtttttag atataagagt gaaagtaaag tgggggagaa taataatggc
    10321 agatcgtaaa ttagaaaagt tattagaaga aacgtggaat ccaaaagaat ttagtgaatt
    10381 ttttatggag aattttgaaa ctgacttagc agtgattgtt aaagatgctc ttagagagca
    10441 agggtatcct gaaactgcaa actatataaa cattaatttt actttgtata ctgaaaataa
    10501 aggaacttgg gatttttggg ctactttagc aaataaggag ttaagtgata aatcagacac
    10561 aggaattcgt aacttttttg aatcaaacag agatgattat atgtatgcta accatcaaga
    10621 taaattgaac tttagagtag agtttgatga aacacctgaa gaatttatag aaagacaacc
    10681 gcctaaagaa aatgtagcaa aggtattgga agatcgttgg aattcagatg aaatagtttc
    10741 aacaattagc gaactaggcg gacaatatga accgctagta gaagcggtta gagaagagct
    10801 aagactgaat aagtttcctg atgttcaaaa tattgatgtt tctcaaattg aaataaacgt
    10861 caagatcacg aataaacttg attatggtag ttgggcagat atagcattag aaaaatacat
    10921 ctactcaacg ttaaaagagt ttatcgaaaa tagaatggat atcatgtatc tacagcatcc
    10981 acagtattta aactttggtg ttgaaatagc tacacctctt gaagaatgga aaatggagca
    11041 agggcttgac tagcctttgc tccatttttt tattttacaa atgaatacag ttcgtcgttt
    11101 ttaccaagaa tgattgtttg cccaactttg agattgtcag gtgatccttc agcggtttgt
    11161 aaggagaacg ttccgttgaa cttatcggat accgttatag gtagctttaa ttctgatcct
    11221 tcctcatctt tgagaattgc tgtttttcgt tcatcaaaat aaacagtctt tattaaataa
    11281 tttttcgtag tgatctcagc agatttgtct ttttttgtag tagtaacagt ttctttagaa
    11341 ttagaggtat tttctacgac tattccatct ttggcatttg agcttgtgtt tatttgattg
    11401 aatattttca gcgacaagat accgctaaga atagtcaata tagaaacaag tgtaattaat
    11461 actgataatt tccttttttt gttcattttt tcttaacttc ctttttgttt tgattagtta
    11521 gatattcctt atctaacaag cctttttagg ctattaaatg aagataaacc ccaaaaaaat
    11581 attgcaatta tgacagtgca atggtactat tattatacaa taaattttgc gaaaggggta
    11641 ggtctaaatc gcaaacaaaa agaaattgaa cctagacaaa tacaacttgt acaccgcaag
    11701 ggaagcaagt ttgattttgg gtaaaggtag aaattatgtt acaaacataa tcaactatta
    11761 tccaaatcgt ttgcctaaag gttcgttcaa gaaagtgggt gacaaaacct atattataac
    11821 ggaagaagga atagaagcat tgcgatcaca aacagaaaat aaaaacaaaa agaaggaatg
    11881 aatatgaaga aaaattcgct tggtatggtt ttatttgcat cagctgtact tgcggggtta
    11941 tcagtaccag taacctcaca tgctgatgaa tggactgcaa acacaccgga tcaaatccaa
    12001 attacaacag gacaatcaag ttatgcgttc aaaaaaggag atactatttg gtcaactgta
    12061 gagaagctta aaagcttagg ttacaagact actgttgctg agtttgccga attgaacaat
    12121 gttgatttgg caaaaggaga acaacggact atcccaattg gacgaacttt caacatcagt
    12181 aaagatacat taacagttaa ggaagcagat ggcgaagtag ttagtcaaac tgttcaaaaa
    12241 gataaacctg atcctgttga aaatacggag caagagaaca aaaaatccga gactgcaaaa
    12301 gaatcggaac caacagcaaa cacttctgat aagacagaaa caagtgcttc aagtgttgat
    12361 ggagcaagtt catctaatac aaataattct acaagtgaga aagaagcatc acagggaaca
    12421 agtgaaagta gcactacgga aactgatact ggaacatcaa caaataactc acaatcaaca
    12481 tcaaatgatg caaatgaatc aaccagtaca tcttctagtg atcaatcaca aacaggttcg
    12541 agtgatgaaa ctgacagttc tacttcacca agtaaacccg aacaaccaac taatgttgtg
    12601 ctaggcgttc catttattag tcaaggtaac acaatgcttt gcgaaggaac atctttgcta
    12661 gaagcgttac attataaagg tgttgcaaca aatcaagatt taatgacttt tgttaaatca
    12721 atgccactat ctcctgataa taatccaaat aatggttttt ctggtgaatg gagacacaat
    12781 gtggatggaa cttatcaagg tatgaatccg gctcctgtag tttcatgggg tgttgctaat
    12841 ggcggaaatg ttgtagatat ttctggttca tcggtacaag gattaaaaga tgagattgta
    12901 aatggaaatc ctgtagtagc gtgggtaact tatgcctttg aacctgctca acataaatca
    12961 atgttttggg gcgatgctat ttggaatcga catgtagtag ccgttgatgg atttaaagac
    13021 ggtttttacc atgttgtcga tcctgtgttt ggggcaagtt ggattaatgc aggatcattt
    13081 gaaacagcat ataacgtatc tcaattagcg gtttcggtac gttaataaaa gagattgttt
    13141 atatactaag tagttaagta tagtctttat ttgtccttgc ttaactactt agaaaacttg
    13201 ttgctcatgg tgggtagaac taaaaggggt gatgctatga atactagagc gttgaaacag
    13261 cttgctttca acgaaaaaag tgattaatag gtgtggtga
//
LOCUS       DAFELK010000072        13148 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFELK010000072
VERSION     DAFELK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.075"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(77..149)
                     /locus_tag="LP433_002496"
     tRNA            complement(77..149)
                     /locus_tag="LP433_002496"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="LP433_002497"
     CDS             530..1099
                     /locus_tag="LP433_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBL2006620.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="LP433_002498"
     CDS             1086..1946
                     /locus_tag="LP433_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2006621.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="LP433_002499"
     CDS             2136..2840
                     /locus_tag="LP433_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2006622.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="LP433_002500"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="LP433_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBL2006623.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="LP433_002501"
     CDS             4677..5993
                     /locus_tag="LP433_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006624.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="LP433_002502"
     CDS             5994..6863
                     /locus_tag="LP433_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBL2006625.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="LP433_002503"
     CDS             6918..7727
                     /locus_tag="LP433_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2006626.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="LP433_002504"
     CDS             complement(7830..8459)
                     /locus_tag="LP433_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBL2006627.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9923
                     /locus_tag="LP433_002505"
                     /pseudo
     CDS             8629..9923
                     /locus_tag="LP433_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(9999..10661)
                     /locus_tag="LP433_002506"
     CDS             complement(9999..10661)
                     /locus_tag="LP433_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL2006628.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10886..11170
                     /gene="groES"
                     /locus_tag="LP433_002507"
     CDS             10886..11170
                     /gene="groES"
                     /locus_tag="LP433_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBL2006629.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11221..12846
                     /gene="groL"
                     /locus_tag="LP433_002508"
     CDS             11221..12846
                     /gene="groL"
                     /locus_tag="LP433_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBL2006630.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4370 a         2265 c         2833 g         3680 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatatg
     9061 cacgtttagt aagacttgcg aaagggtgga agcaaagaga gaagatacct gaaaatgttt
     9121 ggcagtcttt tacttcattg attccaatca ttgttatagt cacttttacg cttatcggtt
     9181 cagcggtttt tcaacagttg ttcagaatga ctgttgttca aggagtatgg acatatgtcc
     9241 agcttcccat tcaatcgttc atagacacgt tgtttggtgt gcttttatta ggtttttttg
     9301 ttccgttttt atggttattt ggtcttcatg gatctgcgat ggtcaatggg ttggttagtc
     9361 ccgtcttgca agcgaattca ttagcgaatg cagaaatctt agcctcagga caagagttga
     9421 cggtggcaaa tggcggacat atcgttactc agcaatttct cgatcagttc atgacggtta
     9481 cgggtgctgg attgacgtta ggggctgtat tttttatgac ggtttttgcg aaatcgaaga
     9541 aatacagaga attaggaaat cttgctcttt taccagcctt tttcaacatc aatgaatcaa
     9601 ttattttttc cacaccgatc gtgatgaacc cgatgatggc tgttcctttt attttcgcac
     9661 cggtcgtttc aggattgatt acctattccg ctttatattt tggattcgtt cctttattta
     9721 cagcagtcca agtcccttgg acaacaccgc cgatcctctc gggtttctta gtaggcggag
     9781 tgcctgcagc gattttacaa ggtatcgtgt tgtcaattag ttttttcatt tatttcccat
     9841 ttttgaaaaa aatagattct gcaaactgca aaaaggaaag acagacaaaa aatgatggag
     9901 cagcagaaaa gatgaacgac taaaaaacaa aaatactcct gtcgctttag attgggaaaa
     9961 tcaccaatct aggatgacag gagtatttat agtcatgttt atactagccc tttttggaca
    10021 gctaattgaa caagaacaac taatgtgttc attcctacgt gtgtgatcat cgatgtccag
    10081 atccgaccag ttgctttgta ctctaggctg aagaagaaac ctaggaaaaa gtagattagc
    10141 agatgaccat cattatgagc aaacgcaaac agcaaagagc tgatcactgc tccgacccaa
    10201 aaatttgaat atcgactgat gatccccagt atactgcggc ggaatacgaa ctcttccatg
    10261 atgggtccag caacagttgt cgccaaaata aaagcgggtg cttccatgat catctggatg
    10321 atattttgtg tattctcgga aggggttgct ttgccaaaca atacagattc taacatgaca
    10381 gcgatgcttt gcagaatcaa tgcgacaaag attccaacca atccataaat aacaatcttt
    10441 ggagcagaag ctttttttac cgctgattcg atcgctaagg gttcacgttg cttaaaataa
    10501 aaaatagcta ggacaacggc gcctagtata tacatgactg cagttgctgt gatcaattca
    10561 gacgtagatt ttacaagtcc tatcgaagct aggatcaagg gtgagataaa aattagacca
    10621 tagcaaaaaa tgctgaggaa gctatatttt tttaaagaca tgtaattcct ccttttaagg
    10681 gataacaagc atgcaaggca agcttatatc gattgatttc aattatatca taatttcaat
    10741 aagcagctgt cagaataaaa tttcttttct ttgatttaaa agcttgcaaa aaagagggag
    10801 aatgagtatt attaaaaatg taggttagca ctcgaaggtt aagagtgcta acagattaaa
    10861 aaaagagtta tcggagggat ttatcgtgtt aaaaccatta ggtgatcgcg tcattatcga
    10921 agtcgcaaaa gaagaagaaa aaactgtcgg aggaatcgtt ttagcttctg ctgctaaaga
    10981 gaaaccccaa actgggacag ttgttgcagt cggtgaaggc cgtttgttag aaaacggtga
    11041 aaaagttcct gccgctgtaa aagcaggcga ccaagttatg ttcgaaaaat acgccggtac
    11101 agaagtaaaa tacgaaggaa aagaatatct gatcgtcgca ggaaaagata tcatggcgat
    11161 tgttgagtaa atttggaaga taaaaaaata atcaaaaata atcaatgagg tgaatcaatc
    11221 atggcaaaag aattgaaatt tgcagaagac gcacgcgcag ctatgttacg cggggtagat
    11281 aaattagcag atacagtgaa agtaacatta ggacctaaag gccgaaatgt cgtactagaa
    11341 aaatcttacg gctctccatt gatcacaaat gatggtgtga cgatcgcaaa agaaatcgaa
    11401 ttagaagatc attttgaaaa catgggtgca aaacttgtat cagaagtagc atcaaaaaca
    11461 aatgatattg caggagacgg tacaacgaca gcaactgttc tgacacaagc aatcgttcgc
    11521 gaaggtttaa aaaacgtaac tgcaggtgct aatcctctag gcattcgtcg cgggatcgaa
    11581 ttggcaacaa aagcagcagt cgaagaattg cataatatct caactgttgt tgattcaaaa
    11641 gaagccattg cacaagtagc agctgtttct tcgggttctg ataaagttgg acatttgatt
    11701 gctgatgcaa tggaaaaagt tggaaacgac ggtgtcatca caatcgaaga atcaaaaggg
    11761 atcgaaacag aactagatgt tgtagaaggt atgcagtttg atcgtggtta cttatcacaa
    11821 tatatggtaa cagataacga caaaatggaa gctgttctag aaaacccata tatcttgatc
    11881 acagacaaaa aaatctctaa catccaagat attctgccat tgttagaaca aatcttgcaa
    11941 caatcacgtc cattgttgat tattgctgac gatgtagatg gtgaagcatt gccaactctt
    12001 gtattgaaca aaatccgtgg aacattcaac gtagtagctg taaaagctcc tggtttcggc
    12061 gatcgtcgta aagcaatgct tgaagatatc gctattttga caggtggtac agtaattact
    12121 gacgatctag gtttagaatt gaaagatgta acaatcgaaa acttaggaaa tgcttctaaa
    12181 gttgttgtag ataaagacaa tacaacgatc gtagaaggtt ctggagaaaa agaagcaatc
    12241 gaagctcgtg tgcaattgat caaaaaccaa attgctgaaa caacttctga ttttgaccgc
    12301 gaaaaattac aagaacgctt agctaaatta gcaggtggtg tagctgttgt taaagttggt
    12361 gcagctactg aaacagaatt gaaagaatta aaattacgca ttgaagatgc attgaatgct
    12421 acacgtgccg cagtagaaga aggaatggtc tcaggtggtg gtacagctct agtgaacgtt
    12481 atcagcaaag tttctgctgt agaagcagaa ggagacgtgg caacaggtat caagatcgtt
    12541 gttcgtgctt tagaagaacc aattcgtcaa atcgctgaaa acgctggtta tgaaggatca
    12601 gtgattgttg ataaattgaa gaacgtggaa ctaggcactg gtttcaatgc tgctactgga
    12661 gaatgggtaa acatggttga agcaggtatc gtagacccaa ctaaagtaac acgttctgcc
    12721 ttgcaaaatg ccgcttccgt ttctgccttg ttattaacga cagaagcagt cgttgcagat
    12781 aaaccagaac cagcagcgcc agcagctcct gcaatggatc catcaatgat gggcggtatg
    12841 atgtaagaaa aagcaacttg cttatctaca actgatcatt agtgaaagac agataaaaag
    12901 aggctggaac agaagcgttt aactccaaga aataagaaga aattcacgga aattgctttt
    12961 caaatttttg tgaatttcag cttatttccg aaggagttgc ttctgcttcc gctgtttata
    13021 cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt cccacgctct tttttgtgtg
    13081 taattataat gaaaatagtt atttttaata gttataatat tttatctatt aaaagtaaat
    13141 atccattc
//
LOCUS       DAFELK010000073        13085 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFELK010000073
VERSION     DAFELK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.076"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(79..2199)
                     /locus_tag="LP433_002509"
     CDS             complement(79..2199)
                     /locus_tag="LP433_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2006631.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLELLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2429..3607
                     /locus_tag="LP433_002510"
     CDS             2429..3607
                     /locus_tag="LP433_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBL2006632.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3623..4381
                     /gene="aroD"
                     /locus_tag="LP433_002511"
     CDS             3623..4381
                     /gene="aroD"
                     /locus_tag="LP433_002511"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBL2006633.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4404..4889
                     /gene="ybaK"
                     /locus_tag="LP433_002512"
     CDS             4404..4889
                     /gene="ybaK"
                     /locus_tag="LP433_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBL2006634.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4960..6213)
                     /locus_tag="LP433_002513"
     CDS             complement(4960..6213)
                     /locus_tag="LP433_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2006635.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6329..7678
                     /gene="gdhA"
                     /locus_tag="LP433_002514"
     CDS             6329..7678
                     /gene="gdhA"
                     /locus_tag="LP433_002514"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBL2006636.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7790..9136
                     /locus_tag="LP433_002515"
     CDS             7790..9136
                     /locus_tag="LP433_002515"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBL2006637.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9444..9830)
                     /locus_tag="LP433_002516"
     CDS             complement(9444..9830)
                     /locus_tag="LP433_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2006638.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10098..10247)
                     /locus_tag="LP433_002517"
     CDS             complement(10098..10247)
                     /locus_tag="LP433_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006639.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10709..10921
                     /locus_tag="LP433_002518"
     CDS             10709..10921
                     /locus_tag="LP433_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006640.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11199..12998)
                     /locus_tag="LP433_002519"
     CDS             complement(11199..12998)
                     /locus_tag="LP433_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL2006641.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4292 a         2352 c         2577 g         3864 t
ORIGIN      
        1 ttattctaag atttctcttt accaacatca tttgacaaag agcctaattt tgtcgctgct
       61 ccttttaaat ttattttatc attcggaaga acttgtggtc gttccgtgaa gttcttggta
      121 cgtttgcgtt ttataaagat caacagttga ttgtcccttg tgttcactaa agacactagt
      181 tgacttgtca ccaagagatt tttcagcttc ttttaatttc tctaagccat tcttgtagtc
      241 ataatcactg gtatcaattg ggtctaatcc actattcgta tagaaccgaa gaagatcacc
      301 attattgatt tggtcagaaa cagctaactg tttatcaact ttttctttca gtgaatcaat
      361 ttcattctgt acttcctcag taggttcagt aatagcttca ccagtttcgt tactatagat
      421 cgtaccaccg tagtaagtat attttggtgt aacaaaatca ccatcacgga aagaaacaag
      481 ctgttcatga tctttcgaga atagatcttg tcctaactga atataatttt ttgtatctac
      541 acctagtaag tgaagtaatg taggcaaggc atcaacttgt ccgccgtaag tgtgattgat
      601 tccgccctgt gtttgtccag ggatatggat catataaggg acacgctgca tttgtgcatt
      661 gtcgtagttt gtccaagtag aacttgtttt tccaactaat tcagctagat ttttatttct
      721 tgaattcgag acaccgtaat ggtcaccgta aaggacgatg actgaattat catacaagcc
      781 gctttctttc aaataattga agaattcttg tacggcggta tctaaataat tggctgtcgc
      841 aaagtaaccg ttgatcgttt catcatttgt attggctaac gggaatcctg cttcgtcatt
      901 ggtgaatttt gaataaggat aatggttaga tacagcaatg aattttgaat aaaatggttg
      961 ttgcagaagt tccaagtatt gtacggattg ttggaaaaat ggtttatcat gcaacccgta
     1021 ttggaacgaa ttgtcatcat taacatcata ataagaagaa tcaaagaaat aatcatatcc
     1081 taaattcttg tatgtctcgt ttcgattcca gaatgtacca gcgttcccat ggaataccgc
     1141 actagtgtaa ccttgtgttt gacttaaaat atcaggtgca gcttggaaag tattttttcc
     1201 gcctaattgt gtgaacaagg agccttgatt caagccaaac aatgaatttt ccatcagcgt
     1261 ttccgcatcg cttgtttttc ctgcttttac ttgatggaaa aagttgtcaa aactgaacgt
     1321 gctgttgctg tggtaaagac tattgatgaa aggtgtaact tcaagctgga gaccattctc
     1381 atctgtcaat ttataatcga tcaggaattg ctggaagctt tctaaatgga tataaatcac
     1441 attttttcct ttagcgagcc cgaacaaatc atcatttggt gctgcataat gttcttttac
     1501 ataattttct acttctttca tatcattggg acttgcttct gcccgcactt ggtttgtctg
     1561 gtaagtttga acaccgtcat aaaccatgaa agcattcaag ccaagatatt tgaccaaata
     1621 atcacgagag aatgttcgag tcagcaattc tggacgatca gcttccgcca taaaaagatt
     1681 tcctgagaaa atcataactg ctaatgtaga gatcgcaaaa gccattcttg ctcggatcgg
     1741 gcgagggtcc aacttgattt tttttgcaat cagcagaaca gtcaagataa taaaatcgat
     1801 ccaatagatc acatcatatg ggcgaaacag tcgaatggca ctttctccca gaccactcgc
     1861 tactttccca gcacctaaaa tcgtgttgat cgtaatgaag tccgtgaatt ctcgataata
     1921 agtgacattc gaaaaaacaa gcaatgtcaa aagaaaataa atgaccatca tcgtgatata
     1981 agcaactcta gggcgtctga tataaagagc aattccaagt aataacaatg tagttgcaat
     2041 agggttgata aacaagataa agtattgaat gccactttcg attccgagat ggaaatcaac
     2101 taaataggca aaaatcgttt tcaaccaaag taaaacaact agtaaagaaa aaaatccgag
     2161 cctcttattc aaaaaggcag gtgtttttat acatttcaag ataatcttcc tttctgcact
     2221 tcttaatcac agaagtgtca tgaaaccatg ttacacagct cacttattct catttatttt
     2281 actagtatga caatatagtg tcaattgaaa ccagaagttt atgctgtttc attaaggttt
     2341 tctttaagct tcatgaaaaa atgagcagta agacaagtcc tatgtttttt gttatacttg
     2401 ggaagagaaa gctaaagcag gtgaaggaat gaaagtaaaa gtaaaaaaaa gagcaagcaa
     2461 tcgattgaaa aaaggatatc cactgatcca aaaagaagac cttgctcatc cccaaaaaga
     2521 aaccacgcaa tgggtggaat tagttgattc gcaaaaccaa tttatcgcaa aaggatatct
     2581 aggaaagcag aataagggaa tcggttgggt attgagccag cagaacatcc catttgatca
     2641 atcttttttt gaagaatttt ttgtgaagtc aaaagaaaaa agaactttct ttttttcaga
     2701 tgattctact accgcttttc gtatattcaa tggagaagga gacgggatcg gcggtctgat
     2761 tgttgattat tatgcaggtt atgctgtttt ttcttggtat aacgaaacgt tatatgcaca
     2821 tcgtgaatta ttgattcaag cttttcgtga aatctacccg gaaatcgtag gaggctatga
     2881 gaaaattcga tttgaatcag taaatctgcc tgagagccag ttcatttacg gaaaagaggc
     2941 accggaaccc ttgatcgtaa aagaaaacgg agtaaaattt gccgtttatt taaatgaagg
     3001 attaatgact gggatctttt tagaccaaaa agaagtacgg ggatcattag cagaaggttt
     3061 cgcttctggg aaaacagttt tgaacatgtt tagttatacc ggcgcctttt ctgttgctgc
     3121 cgcaatggga ggggcaatcg aaacaacaag tgtcgatcta gcaaaacgca gtttaaaaaa
     3181 aacacaggaa cagtttgaag tgaatggttt ggatgtcgat cagcaaaaaa tcattgttat
     3241 ggacgtattc gagtatttca aatacgccaa aagaaaacaa tttttatatg acatgattgt
     3301 attggatcca ccaagttttg ccagaaataa gaaaaaagtc tttcgcgtag caaaagatta
     3361 tggggaactg gtcaaggata gtctggatat tttagcagaa gacgggatac ttattgcgtc
     3421 tacaaatgct gcgaatgtct cgatagaaca attccaaaca atgattgaag aggaattcca
     3481 tgccaaaaat gtttcttttg aacaacttgc tttatatcgt ctgccaaaag atttccagac
     3541 gacggatacc tttttagaag gcaattatct gaaagtgttt gtttatcaaa ttaaaaataa
     3601 ccattagaag gagcgatgca gaatggtttg ggtaaaggga ttgaatatag gaagcggtag
     3661 accaaagatt tgtgcgcctc ttatcggggc cgtccgagag gaagtattac gtgaagcagt
     3721 tcttgcacgt gaagcagggg ccgatttagt cgaatggcga gtcgatcatt atcgtgaagt
     3781 tttttctttt gatgaagtag cagaaacatt ggttcttatc catgagatgc ttgatggact
     3841 gccgttatta tttacgtttc gtaccttagc tgaaggcgga gaacaagaca tatcgatccg
     3901 tcagtatcgc gacctttatg aacatgtgat acacacagga ttagtagata tggtcgatat
     3961 cgagttgttc aaagtagaaa gtctaggaaa aagactgata gaggaaatca agtctttaaa
     4021 cattccttta attatcagta gtcatgattt taaagaaaca ccagcagacc ctgtcttgct
     4081 ttaccgattg aatgttatgg aacattttgg agccgatatc ggaaaactgg cagtaactcc
     4141 caataatgaa cgagatgttt tgcggttgat ggagttgact agacgggcaa atgcttttgt
     4201 ctccatgcct attattacga tgtccatggg aaatcttggt aaaatttctc gtctggctgg
     4261 cggaacgacg ggttccgtta tgacatttgg ttccttaagc agcgattcta cttctgctcc
     4321 aggacaatta ccggtcaaag cattgaagca aattattcaa ttattaaatg aaccgttgta
     4381 gaacaagttt gaggtgatat tttttggcaa agaaaaaaat agtaaaaacg aatgcaatcc
     4441 gtatggtcga acaaaaaaag attccctata cagagcacga atatgagtgg gacgaaagcc
     4501 acctaagtgc gtcatcggtc gctgaacagc ttccagaaag ccaatctcat atatttaaaa
     4561 cactggttgc tgtgggcaat gtgacggggc ctcttgttgc tgtgataccg ggagaagccg
     4621 aattgaatct aaaaaaatta gcaaaagttt cagggaataa aaaagtagaa atgctccatt
     4681 taaaagattt ggaagcaacg accggataca tacgtggtgg ctgctcgcct ataggtatga
     4741 aaaaactatt tcctacttat ttagatcaaa ttgcagaaag ctatgaacaa atcattgtct
     4801 cggctggcag aagagggcta cagatggagt tagcacctca agatatctgt gcattaacga
     4861 gcggacaatt tgcagatata aaacaataaa tcatacgtat aaaagaaaga aggaggccgg
     4921 gatgttgttt gtccagtctc cttctttctt ttttatacat tatgctcttt gcccggcatt
     4981 cattcctgct acatgccctg tagcgaaagc cgctgtgata ttaaagccgc cagtataacc
     5041 attgacatcc agtaattctc ccgcaaaata cagaccatca atgattttac tctccaatgt
     5101 tttaggataa atttccttta gagaaacccc tccgccagtt acaaatgatt tctcaatagg
     5161 aaaagttttg ttgattgata gcttaaactc tttgcatagt tgaacaaaat cttgaatttg
     5221 tttttgagag gcttgttgtc ctgtcagatg atccatttca agccgctcaa gaaagaaaac
     5281 taacaatcgc tcaggcaata taccatgcca agcattgacc aagttctttt tggttgcttt
     5341 acttttttct gtcaatatat gaataagctc ttgtttggtt tgtgtaggga aacaatccag
     5401 agaaagtgtc actggttctc ccgttttctc taattcttta ttgacaaaac ttgaacaacg
     5461 cagtgcagcc ggaccagaaa taccgaaatg ggtgaaaagt aaatccatcg tatgttcagt
     5521 caatacacga ccttttttat ttaaaacgcg taaagtgatg tcttgtaaag aaagcccttg
     5581 aagtgttttc tcctgaatat acggttcatc cgatatcaag ggggactctg tcgcataaag
     5641 aggcgtcacc gtgtgaccca ctcgcttcac gatcttgtac ccatctccag tagaaccagt
     5701 agatggataa gtccgtccac cagttgttaa gataatggca ggagcatgga actcttcgaa
     5761 ttccgtgcgt ataccgtaaa ttttatgttc tttgtggatc aatttctcta ctcgagtaga
     5821 gaatagaagc gtcacatcta gttctttcag acgattgagc aatgcttcga taatcgtttt
     5881 tgatttattt gttacaggaa acatccgtcc atgatcctct tcttttaaat gtacgccttg
     5941 tgattcaaag aagttcatga tatcgaaatt attccattgc gcaaacgtac tatataaaaa
     6001 ctttccattt ccaggaatat gtgcaatcaa atcatcaaca ggacgattgt tcgtaacatt
     6061 gcaccgacca ccacctgtca tcagtagttt ttttcctgct tttttgtttt tttcgatcaa
     6121 gagtacgcgt gcgccttgtt cagctgcact gatcgctgcc atcatcccgc ttgttccagc
     6181 gccgactacg atcacatcat acagtttttc cattccctca cctcaaggaa agtgtagcat
     6241 atctgaagaa agaaaacaga aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
     6301 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
     6361 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
     6421 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
     6481 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
     6541 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
     6601 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
     6661 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
     6721 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
     6781 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
     6841 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
     6901 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
     6961 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
     7021 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
     7081 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
     7141 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
     7201 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
     7261 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
     7321 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
     7381 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
     7441 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgcccagcg
     7501 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
     7561 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
     7621 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
     7681 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
     7741 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
     7801 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
     7861 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
     7921 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
     7981 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
     8041 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
     8101 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
     8161 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
     8221 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
     8281 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
     8341 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
     8401 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
     8461 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
     8521 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
     8581 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
     8641 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
     8701 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
     8761 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
     8821 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
     8881 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
     8941 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
     9001 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
     9061 caagaaaaac atgttcgcac ttctaggcaa accgggcttt gaagatcttg ctaaagaatt
     9121 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
     9181 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
     9241 ttcagaataa ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga
     9301 ttgattgcct tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa
     9361 ggttaattct gtttttttgt tttctagaat cagtaagcaa aaaagcactc acttcgagtg
     9421 cttttttgcg atatattctt agcttaagat aggcctaatt tttcttttac agatgagggt
     9481 accttatcgc tggtaattac ttttttctct atgatccgct tttcgcttgc tttcaactgc
     9541 aagatcgttc cttcggtgta agcagaacca ttggcagagt caccagaagt aatgacatcg
     9601 aaatctaact gtcttttttc accgttttca gcataagcat ctacgttgta tttaaaacct
     9661 cttccaatta cttccccatt atctgctttg atatcagttt ctgcaggcat tggagctttg
     9721 actaccgcat aataatcttt acctacataa gtagactgat agtagtccca acctttccat
     9781 cctataaaag caatcaatat gataacgatc aaccctaaaa tttttttcat gaaagatctc
     9841 cttttttatt tttattatat taaatattat acagataata acggaatatt atcatcgaaa
     9901 cagctaacaa aattgtcata aaaaacgaga tggttgatat tagaacttgt gtttttgttt
     9961 aggtctagag ataaagagag acaatttcca aatatatgta atgaatacaa aaagacgttt
    10021 gtcgcggatt accgttacaa acgtctttta ttgattttcc gagatctcat cagtcgccat
    10081 ttggaatggt tcactcctta tctagattcg tttaatgctc ggactgcttg ttcgattgta
    10141 ataccaaacg caacgttatt ttcgttttgt gcatcaatcg ccataaaacg gttagaagtt
    10201 gtatcaaaag ctacgcggta ttgcatattt gtttttgtaa acgtcataaa attcatctcc
    10261 tttgtaatgt aatttagttc ttgaaagttt cctttaaact ttcgaactta taccaagttt
    10321 agcatcgtac gttttttgat gcaattaaaa agcatttatc attttcctta tttatttttt
    10381 cttaaatggt ttagctattt tcttttaatc cgataagtag cccaatcatc aaggttacaa
    10441 atactattgc ttgaatataa atcatatgct cacctcttta taaataactt agcaatataa
    10501 agaaaaaaac gcacgaacaa cataggaata taaacaaacg tttttgtcac aacgtctaag
    10561 atcgtgttaa aaaatagtta tctaaaaagc agaaagatac tcaaaataaa aaataaaaaa
    10621 atgaataaaa acgttttcaa atacaaggta atttgttatt ataaaataaa gaaaaaacaa
    10681 aataaaaata aagaaaagag ggaatgaaat ggtaaaagca gaagtaggaa gatcttatat
    10741 atgcaaaccg atcggagtat ctcatgaact aatcggctgt attgaacgta catatatcaa
    10801 cacggctgtc gtgtatgttg aaagttatga ccaacgagac tatcaactta tcaatgaaag
    10861 caagtatcgc atgctcgtaa aattctgtga tattagcgca cctactgaat tggtttctta
    10921 aacagtattt ttgagaattc gcaagaactc ccttataata taaataaaga cagaagggag
    10981 cgagaagata tgccaaaaag aaaaagttca gggaaaatgg gaattattct tgcagtgatc
    11041 tctgcaattc ctgctatttt agctattgtt cgtgcgatga aggaatcaag agaaagttaa
    11101 gcacacatta tgagcgtcaa acaaaaaacg catatacctg cggtggcagg ttatgcgttt
    11161 tttgttgtat aaagactttt ttcattaacg atttttgatt agccgactcc caaaacaaaa
    11221 tttagcagtt tatctgaata agtgatttct tcatctgttt gtttcacact ttcatttagt
    11281 agtcccatct catcggttat gataccatcc acaccataaa acatcatgcg actcatggca
    11341 tctgaatcgt tgattgtcca tacatatact tcttttccgt cttggtgggc agaattaatg
    11401 aagttacggt tgatcgtact atattccatt gtcagaaaat cagcaggcgt cacagggggc
    11461 ccaacaatat tgaaaggtaa gatgtagccc acataaaagt ttggttctgc ttcttttaaa
    11521 tctgaaacgg tttggtacgt caaactttgc aaaatatgat ggttctctaa gataactttg
    11581 cggtatttat ggacaaatcg ttcgacaagg tcatccgaat cttttttaga ggtcttgatc
    11641 tcaataagta atttttggtt tagcttatgt gctttttcca aataagaatc aaaagaacaa
    11701 acaggggctt gcactccgtt ttcagtaact gtaagatttg tcaattcttt caatgtaaga
    11761 tcctgtggtg ttccatttac ccctgttaag tgacgaagat ttgcatcatg catcactacg
    11821 aaatgaccat cttttgtttc ctgaacatcc atctctacat aatcaggatg atagtctctg
    11881 cttgtttttt caagtgcttc taaagtattt tgcgccccat tttgggtact cacacctctg
    11941 tgagagacag tcactggttt tgtctgaaca gctgaagtca gataatccat attgtaaaga
    12001 cagacgccaa taccgaaaaa aactgcaaaa agagtcaaac cagtgttttt cagcgcagag
    12061 aaacgcaagt tgggggcttg tgggataaac cacttaggga tctcaggcaa gaagccttcg
    12121 tcatccatga aatcaacaat gatataaaaa atccctacgg tagacatcac gatattgaat
    12181 aataaaatcc cttgtaaaag cgtcatagca aacacagcgc tgatcaatgc atagtctggg
    12241 aaaaattgtt caaccatact ttgtgccaaa ataacaacga tatatcctaa agaagaaagg
    12301 agtaaaatcg taccgccaat cacaataaat tggcccgtga tggccaaaag acgcgatttg
    12361 gtcaatgacc agctttcccg aatggctgct cgaaaagaac gatctcgtag aatcatttcc
    12421 ggtaaagcaa aaatcagtcg aatcccaata tagccaagga aaatataaac gagtaaaaag
    12481 gaactgacga tgatccaacg attagcaaaa ataaaatcca taatgaaagc ggggattttt
    12541 atttttgaca gtagatcaga attaaaactt aatccgctga tcggtagaat caataaaaaa
    12601 taagcaagga aaaacaaaaa agtaatgggt ctcactttct tcagctgaag tatcgtcaag
    12661 tgtaagagtt gcttcaaaga gattggttct ttctttttaa taaaaaaaac actcatcaaa
    12721 agaaaagtaa attcgaaata aactaacagt aaaatcgtca tcaaaactac gattaacgag
    12781 agtagaaccc caggatgttg agaaaaaatt gaaggaatat tgtcataaga caaatagtca
    12841 attgcccctc ggtgtaaaat aaaacgggtc gtactgctca ataagggtaa acaaataaat
    12901 aaaataaagc catgcatcag caagacatca cggaaataag cttgtgttcc ttttaaaaag
    12961 tcccaagcat tacctaagct acgtttcaaa taattcatcc tatcacctgc tcttcacatt
    13021 gtagcgcaaa tctaatgaaa aaggaaaggg tgcagtgtgt tttgcagacc ctttcccaga
    13081 tttaa
//
LOCUS       DAFELK010000074        11856 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFELK010000074
VERSION     DAFELK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.077"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP433_002520"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP433_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBL2006642.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP433_002521"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP433_002521"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBL2006643.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="LP433_002522"
     CDS             complement(2169..2906)
                     /locus_tag="LP433_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL2006644.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="LP433_002523"
     CDS             complement(2997..3524)
                     /locus_tag="LP433_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006645.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="LP433_002524"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="LP433_002524"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBL2006646.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="LP433_002525"
     CDS             complement(4401..4886)
                     /locus_tag="LP433_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBL2006647.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="LP433_002526"
     CDS             complement(5039..5236)
                     /locus_tag="LP433_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006648.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP433_002527"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP433_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBL2006649.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP433_002528"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP433_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBL2006650.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="LP433_002529"
     CDS             9211..9423
                     /locus_tag="LP433_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBL2006651.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="LP433_002530"
     CDS             9425..11104
                     /locus_tag="LP433_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL2006652.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(11358..11558)
                     /locus_tag="LP433_002531"
     CDS             complement(11358..11558)
                     /locus_tag="LP433_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2006653.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(11708..>11856)
                     /locus_tag="LP433_002532"
     CDS             complement(11708..>11856)
                     /locus_tag="LP433_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HBL2006654.1"
                     /translation="EIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRYFSLREEGM
                     MEEK"
BASE COUNT         3425 a         2565 c         2064 g         3802 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacctgc cacaagagaa attgtctctt
    11281 gtggcaggta tttttgttac tcgctttgtt ctctcgtaaa aattgatgtc taccatcaat
    11341 ttgatttaca gataaaatta agcttttaca acgtttgcag cttgtgggcc gcggtctgat
    11401 tcttcaacgt cgaaagtcac tgcttgacct tcttctaatg ttttgaatcc gtcaccttgg
    11461 atagctgaga agtgaacgaa tacgtcgctt ccatcttcac gtgagataaa tccaaatcct
    11521 ttttcagcgt tgaaccattt tactgttccg ttttccataa taatatcctc ctcgtgccaa
    11581 aagcactaat ttaaattgta acattgctcg tgtacgatag aggtgcaaca gatgtttcaa
    11641 cttctattcc caaacaaaat tacaatataa ttgtacactt gcttcatttt ttttgcaaga
    11701 aagcaactta cttctcttcc atcattcctt cttctctcaa actaaaatat cgtttgcgtc
    11761 cgatgatcaa gtggtccagt acagtgatcc ccatcatttc tccacacttt tgtatccttt
    11821 tggtaaaatt catatcctgc tgcgatggaa tttcat
//
LOCUS       DAFELK010000075        11509 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFELK010000075
VERSION     DAFELK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.078"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(205..690)
                     /locus_tag="LP433_002533"
     CDS             complement(205..690)
                     /locus_tag="LP433_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBL2006655.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    780..1125
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1170..1811
                     /locus_tag="LP433_002534"
     CDS             1170..1811
                     /locus_tag="LP433_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2006656.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1830..2465
                     /locus_tag="LP433_002535"
     CDS             1830..2465
                     /locus_tag="LP433_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2006657.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2483..3298
                     /locus_tag="LP433_002536"
     CDS             2483..3298
                     /locus_tag="LP433_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2006658.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3617..5053
                     /locus_tag="LP433_002537"
     CDS             3617..5053
                     /locus_tag="LP433_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2006659.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPESVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5242..7689
                     /locus_tag="LP433_002538"
     CDS             5242..7689
                     /locus_tag="LP433_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL2006660.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7919..8986
                     /gene="rlmN"
                     /locus_tag="LP433_002539"
     CDS             7919..8986
                     /gene="rlmN"
                     /locus_tag="LP433_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL2006661.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9179..10282)
                     /locus_tag="LP433_002540"
     CDS             complement(9179..10282)
                     /locus_tag="LP433_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2006662.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10835..11383
                     /gene="aac(6')"
                     /locus_tag="LP433_002541"
     CDS             10835..11383
                     /gene="aac(6')"
                     /locus_tag="LP433_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL2006663.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3819 a         1945 c         2484 g         3261 t
ORIGIN      
        1 aaaaagaagc atttttatat atgcttcttt tttcgtagaa tcaataaata tggatttggc
       61 taactatgga agaatactcg tattagtttt cagcgttcat actagttgtt acattgtttg
      121 attggccaaa agaatttctg atatattttg tgctaaataa agaaaaagac gcttgaattg
      181 ggaaataaga aaactactct atcattacaa attttcataa actggcagat gttctaagta
      241 aacaagtatc ttttcaaagt cggaaaaatc cataatcaac gtagtggtat tgatatttgg
      301 atgaaagcct acggtatctt gacgatcaat agcagcatcg atcacgactt ggattttttt
      361 ctctttgtcg tgcatcaatg ctaatggagt cactgtacct gctggaacgc ctaggaggtc
      421 aggaagctgt tcttcagaaa caaaagataa gcgcttttct tttaattgtt cagctagttg
      481 ttttaaatcg gcgtgctttt catcaggcaa gatgacaaga tagatttgtt ttccttttct
      541 tgatttcaat aatagatttt ttacttgcgg accaggtagg gaaaaaggga catttttgac
      601 tgacgtaatc gcaggatgat cgactttttg aaaagagata cccagttttt ttagtagttc
      661 ataagcttct tgttcggttg cacgactcat cgcgcatcac cctccttttt ttattagtgt
      721 atcataaaaa agagttgaca aatgaaaaat aatcatgtaa attacacgta aagttaaaac
      781 aaatgacatc gaaaagaaga gtagccgtta ggtgttttta gagagtctct ggttggtgga
      841 aagaggcagc agttaaccgt gaaacacatc ttggagtcga ttttctgaag cgtatagtag
      901 gaaaatccgg ggagcccgtt acagctgcgg tcgttgctag atgaccagat aaggctggct
      961 tttccgtgag gagtcggtaa aaaaaggtgg aaccacgtga ttaacgtcct ttgatcttcg
     1021 gatcaaagga ctttttgttt tcatctgaac ggcaacgact gtgtgaggtt ttttctgcaa
     1081 ggaaaaaata aacagaggtg gaaccacgta taatacgtcc tcttggcatt tgccaagagg
     1141 atttttttat tttaaaggag gaaaagaaga tggagtattt gattgaagtt atgccgcaat
     1201 tattagtagg agcactcaca acattgaaat tatttttatt taccttgatt ggctcattac
     1261 cattagggat tgttttagca ttaggattgt ctttgcattt taagccgcta cgctacttgc
     1321 ttcaaacata tgtatgggtt atgcggggaa caccgctgtt gttgcaactg atttttattt
     1381 tttatgggtt gccgacgatt gggatcgttt ttgatcgttt cgaagcagca ctcattgcct
     1441 ttatcttaaa ctatgcagct tattttgcag agatctttcg tggagggata caatcgattc
     1501 ctcaaggtca atatgaagca gcgcaagttt tgcaattaag tccctttcaa acggtgacga
     1561 aaatcgtcat cccacaagtg acaaagattg ttttaccttc tgtagggaat gaagttatca
     1621 acttggtcaa agattcttcc ttgatctata tattaggttt aggtgacgta atgcgtgctg
     1681 ggaaaatcgc gatggaacgc gacgcgactt tactgccttt gctaggcgtg gcaatcatct
     1741 atcttacatt gactggtatt ctaacaatcg taatgaaaca agttgaagga aaattaaatt
     1801 attaccgcta actgatagga ggaagaaata tgattgaatt gaagaaagtg aacaaagcat
     1861 ttggtgaaaa aaaaataatc aaagatttga atctaatcat tccagatggg aaaacattag
     1921 ctatcgtagg tccttccggt ggcggtaaaa ccacgctttt acgtatcttg gctggcttag
     1981 aaagttctga cagcggagaa ttttatttag acggtgtacc gttcaaccca ttcgagctta
     2041 aaatgaaaga acaagttgta ggagtcgtat tccaagactt ccagctattt ccacatctga
     2101 atatttttga aaacattacc ttagcaccaa aaatggtatt gaaacagaca aaagaagaat
     2161 acaccaaaaa agcagaagaa ttagcggctt cattagggat tagtgattta ttgaatatct
     2221 atccttatca gctttctggc ggacaaaaac agcgggtagc gattgccaga gcattggcta
     2281 tgaatccacg ggtattggct tatgatgaac caacaagtgc tttagatcct gaattacgcc
     2341 agcaagtcga gcgtttgatc ctatcattga aagaagatgg ggtaacccaa attattgtca
     2401 cccatgattt agtatttgca gaaaatgtcg gtgatcaatt actaaaagtt tccccaattc
     2461 attaagaaag gagaagatag agatgaaaaa aaccagtttt ctattcgctt tgatcgcagg
     2521 tcttcttctt tttgcaggct gttcgaacaa aaaaacttca gcagataatt gggcgactat
     2581 caacgaagag aaaaaaatcg ttataggttt agacgataca tttgttccta tgggatttag
     2641 agataaagac gggaagctca caggatttga tattgattta gccaaagcag tctttgaaca
     2701 atatgggatt acggtagact ttcagcccat tgactggtca atgaaggaat ttgaactgaa
     2761 caatggaacg atcgatttga tatggaacgg ctattccaaa acgccggcaa gagaaaagaa
     2821 agtgcaattt acaaaacctt atatggaaaa cgatcaagtg ctgatcacac ctaaagaatc
     2881 aggaatcaca aactttggac aaatgaataa taagagatta ggtgcgcaaa atgggtcatc
     2941 tggttatgat gtatttacga aacaaccaga agtattaaaa gagatagtca aaaaccaaga
     3001 tgctgttttg tatgatagtt ttaatgaagc attgatcgat ctgaaaagca gacgggtcga
     3061 tggtctgctg atggataaag tatacgcaga ctattatttg aaacaaagaa acgaactaga
     3121 agacttcaac ataacaaaag gttcttatga gagtgaggat tttgcagttg gtgcacgcaa
     3181 gtcagatagt acattagtga aaaaaatcaa tgaagcccta gatcaactag agaaaacagg
     3241 tgaattccaa aaaatatccg ataaatggtt tggcgaagat gttacgccga gaaattaaca
     3301 aataggggac tgtgacaaaa gacgtgtcac agtccctttt tccgaataaa cagtgttctc
     3361 ctgccaactc cttgtgactc ggagctgaat ggcaggctca caacctcttg gtaaacggtg
     3421 ttcaaaagcc agtttttcgg tattaagcca aatttatgca aaaatgtaga aagccatttt
     3481 cacaaaattt ttcttactac tcgaaactaa gcgacttttt cacaacctcc tttacataat
     3541 tttattttgt tgtggaaggg gtttcgtgtt attctaaaag aggaacgatt gaaggttata
     3601 ggaaaggaag agatgaatgg aacacaaaga acttacctca tttccaaaag attttctgtg
     3661 gggctctgct tctgcagcgt atcaagtaga aggagcttgg caagaagatg ggaaaggaga
     3721 atcagtctgg gatcgatttg tacggatacc tggaaagaca tttaaaggaa cgaacggtga
     3781 tttggcagta gaccactatc atcgttataa agaagatatt gctttaatga aagaacaagg
     3841 tctgaaagct taccgcttct ctgtagcttg gacacggatt tttcctaatg gacgaggaga
     3901 agtcaatcaa gctgggctcg ctttttatga gagattgatc gacgaattga ttgaaaacga
     3961 tattgaacct atgttgactt tatatcattg ggatcttcca caagcattgc aagatgaata
     4021 taatggttgg gaatcacgtc agatcattga agatttcact cattatgcag aaacattatt
     4081 tgaggcattc cgcgggaaag tccattactg gattagtttg aatgaacaaa atatcttcac
     4141 ttcattaggt tatttgttag cagcacatcc gccaggtgtg acagacccga aacgaatgta
     4201 tgaagttaac catattgcta atttagcaaa tgcatctgtc atcaataaat ttcacgagtt
     4261 agaaatgcct ggaaaaatcg gaccaagctt tgcgtatacg ccaaattatc caattgacag
     4321 taatcctgaa agtgttctgg ctgctgaaaa tgcagaagac ctgatggcca attattggat
     4381 ggatgtctat atgtggggaa aatatccgat tgctgccatg aggttcttag aagaaaaagg
     4441 atgggcacca acgattgaag ctggcgatgc agaattgcta gaatctgcta aaccagattt
     4501 tcttgggatc aattactatc aaacggcgac gaatgcattc aatccattaa acggagttgg
     4561 tgctggaaaa atgaatacga caggaaaaaa aggttcatca gaagaaactg gagttcctgg
     4621 aatgtataaa aaagttgaga atccatttgt cgaacgaaca aattgggact gggagattga
     4681 cccagaagga ttaaggatcg gactgcgtcg tatcacaagc cgttaccgca tgccggtact
     4741 gattacggaa aatggcttag gagagtatga caagttgaca gaagataaac aaatccatga
     4801 cgactatcga atcaattact tacaaagcca cgtcaaagcc atcaaagaag caatttcgga
     4861 tggagcagaa gtcctaggct attgcacctg gtcttataca gatttgctta gctggctgaa
     4921 cggttatcaa aagcgatatg gatttgtata tgttgatcaa gacgaaacac aagaaggatc
     4981 tttggaacga tataagaaag acagttatta ctggtaccaa aaactgattg aagaaaatgg
     5041 agagaacctt tagttcacat acttaaaaca agaaggtacg gctggatatg gccgtgcctt
     5101 ttcttgataa aatcatttag aaattaagaa aaactgtaaa ataagctgaa aaatgaaaga
     5161 aagcgtcagt tctttcaaac aaaactttag ttcccttact tttttttgta taatgaaact
     5221 tgatgaaatg agggataata aatggcacaa aagaaacggc ctactaaaaa aaggaaaaag
     5281 acgaaaaaaa cgaaaaagca aaaacagcag caggaacaaa tgctgacgat tggtgttggg
     5341 tttgccttga ttttatttgc tgtcttcggc tttttaaaat taggtttttt aggaatattg
     5401 attgcaaacg gctttcggat cattgcagga aatacttacc aaatcctctg tcttttatta
     5461 gccgtattag gattttggat tgtcattaag aatacagagt tttcaattgg taaaaaccga
     5521 cgctggtttg gcggcatact cttttatttc ggtatcttat tattgttaca tgcccattta
     5581 tttggcaaac tccatactgg ggaaccaaat atcatgggga cgacatggga tttgttagcc
     5641 agtgatataa aacaaagtca agtagacaat aacgttggtg gtgggatgat tggagcaatc
     5701 ctttatcatt ttacttactt cttgattgca cagcctggaa gttatttagc agcagtgcta
     5761 ttactggcag gaggagcatt cctgttcagt aatctggaag gctatcagct gttaaatggt
     5821 atccaatcaa ttggagaacg agtacaggaa ttattggaag gtgatcctgc caagcaagct
     5881 cgaaagcaag cggcaaagga agagagaatg aaacagcgcg cagaagcgaa agaagcaagg
     5941 cgcttagctg caaaagaagc tgcagaaaaa gaagctgcag aatatgagaa gaaaaaagcg
     6001 gtgagccagc aaagggaaaa tactgctgat gaatggcagg aaccagaaaa tacagagccg
     6061 gagcagctaa gttttgttcc aatcgacagt tttcaagaaa atatccatcc tgcgaatcta
     6121 gagaaaccag taccagatac accaaaacag accaatacag cagaaggttt ttcagatgag
     6181 ttgccagagg atgacggtac ctcattagaa tttgagattg aagcagaaca ggaaaatcaa
     6241 gactatgaat taccgacagt tgatttgctt gattctatac caactgtgga tcaaagtgat
     6301 gagtataaaa aaattgaaaa aaatatcggc gtattagaac aaactttcca aagtttcggt
     6361 gtcgatgcca aggtcgtcaa agccagctta ggaccatccg tcacaaaatt cgaagtccag
     6421 ccggctgtag gggtaaaagt aagtaaaatt gtgaacttaa cagatgatat cgcgcttgct
     6481 ttagcggcga aagatgtccg gatggaagca ccgattccag gtaaatcact gattggtatt
     6541 gaagtaccaa atggaaagat cagtatggtt tcctttagag aaatcatcga agcacaacca
     6601 aaccacccag ataaattact agaagtacct ttaggacgtg atgtttctgg acgggtacaa
     6661 acggctgatc tttcgaagat gcctcactta ctcgtggctg gttcgactgg tagtgggaag
     6721 tcagtagcaa ttaatgggat tatcacaagt atattaatgc gtgctaagcc ccatgaagta
     6781 aaactgatga tgatcgatcc gaaaatggtt gaattgaata tgtacaacgg catacctcat
     6841 ctgttgacgc cggtcgtgac gaaccctaga aaagcagcgc aagccttaca aaaagtagta
     6901 caagaaatgg aagaacgata tgaaaaattc gcggcaaccg gagtaagaaa tatttctggt
     6961 tacaatgaat ttgttcaaca gaaaaacttg gaaaacggaa cgaaacatcc aaccttacca
     7021 ttcatcgtag tgatcgtaga tgaattagct gatttgatga tggtagccag caatgaagtt
     7081 gaagatgcga ttattcgttt agcgcaaatg gctcgggcag cggggattca tatgatccta
     7141 gctactcaac gtccaagtgt ggatgttatc acaggaatca tcaaagcaaa tgtaccttcc
     7201 agaatggcat ttgcggtatc aagcggtaca gattctcgga cgatcattga ttctaatggg
     7261 gcagaaaagc tcttagggcg aggagatatg ctattcttgc caatgggtga gaataaaccg
     7321 atccgtgtgc aaggagcatt catttctgac cacgaagtag aacgggtcgt tcaatttgtt
     7381 acagatcagc aagaagctca ttatgaagag aaaatgatgc cgacagatga agttgaaacg
     7441 acaggtgctc cagaacagcc acaagatgag ctgtttgaag aagcaaaagc acttgtcgtt
     7501 gaaatgcaaa cggcaagtat ttcccttctc caaagaagat ttcggatcgg ttacaaccga
     7561 gcagcacgtt tagtagatga actggaagct catggagttg ttggcccgtc agaaggaagc
     7621 aagcctcgga aagtattcat tgagcaggaa gaaacatcag aaacgttgcc ggacgataat
     7681 gacatgtaaa acttgtgtga tgaagggttg aaaaacgaat aaccaataaa aagacaaggc
     7741 atgatgatac caaaagaaaa aatggttttt ttccatcttt tctaatacgg tatgatgtct
     7801 tgtcttttta gtttttgtga gattaaagtt ctattcgatt tatttgtgaa gtattgcatt
     7861 aaggaaatga atcatgtata gtatgtagcg aaactttgag aaaaagaggg aaaatacttt
     7921 ggaaaaacag tccatttatg gcttgacgaa tgaagaatta atcaattggt ttatagaaaa
     7981 cggcgagaaa aaattccgag ctgcccaagt ttgggaatgg ttgtatcaaa aacgtgtaag
     8041 taatttcaca gaaatgacga atctatcgaa acaattgatc gaaaaattat cggagcattt
     8101 tatcatcaat cctctaaaac agatggtcgt ccaagaagct tcggatggta cagtaaaata
     8161 tttgtttgaa ctccctgata aaaacatgat tgagactgta ctgatgagac aagaatatgg
     8221 cttgtcagtt tgtgtgacga cacaagtagg atgtaatatc ggctgtacgt tttgtgcaag
     8281 cgggctgctc aaaaagaacc gtgatctgac tgctggagaa attgttgcac agatcatgat
     8341 ggtccaacat tattttgatg agcgcaatct tggcgaacgc gtttcacatg tcgttgtaat
     8401 ggggatcggt gagccatttg ataattacga caatgtaatg gactttttgc atatcatcaa
     8461 tgatgccaaa ggattggcaa ttggtgctcg gcacattaca gtttccacta gtggattagc
     8521 acacaaaatc aaggaattcg ctaataacgg cttgcaagtc aatctggcta tttccttgca
     8581 cgcgccgaat aatgaggtgc gaacatcgat catgcggatc aaccgaagtt tcccaattga
     8641 gaaattgatg gaagctgtgg atgagtattt agagaaaaca aaccgtcgaa tcacgtttga
     8701 atatatcatg ttgaatcaag taaatgatag accagagcat gcgcaacaat tagcagatct
     8761 attaaaagat aagaaaaaat tagcatatgt caacttgatt ccatataatc cagtcagtga
     8821 acatgatcaa tattctcgca gtccaaaagc tgatgtattg agattttatg atgtattgaa
     8881 gaaaaacggc gtaaactgtg tgatacgtaa agaacatggt acagatattg atgcagcttg
     8941 cggacaattg cgaagcaagc aaatgaaaaa aacagttgcc aaataatcgt atcctactcg
     9001 ttttttcaat taccataaaa ggagcagttt tcttaattaa ggaactgttc aacttaaata
     9061 agagaaaaga ttctatagcg aaagctataa agcttttttt gacaagaaaa accctcatca
     9121 agcaaagaaa tgtcctcaat ttgatgacag cctgcttgat gggggtttta gcaattattt
     9181 aactgatttt cttatatcct tgctggcttt cttgtgtagc atgataagtt tctacgtcaa
     9241 gaatggcctg tttaaatttt tctcgggtga tttcataagg cacatgttta atatcatttg
     9301 ttgccatggc tttatctaag attgcttcta aatcggtcgt gacattgaga ttcatgtcgg
     9361 ttaacgatac tggaagttgg ttctttttca taaacacata gattttatca aacaaatcga
     9421 actgctgatc catcatcaat aaggtcagta caccataact gacagatgct ccgtgaaggt
     9481 atccctccat tttttctaga acagtcgtac cgtaatagaa tgagtgtgcc atagcagaat
     9541 tatagttatt gttaactaaa acagaaacca atccggtagt aacaatgata tccgaaacga
     9601 cttgttcaat tgcatatgag ggacgatcgt cggcactatc tttcaatgct tgcgtaccat
     9661 aagtcaagag acgatcaatg cacatttttc cgatttggat tcctaatcta tccgtgtagc
     9721 ctagatcatc gccacgagca gaaaaagtag attcgacttc tttggataaa gcatcgccaa
     9781 tacctgccca taagtattta tcaggtgctt cggcaataat tgctgtatca atgaaggtgt
     9841 gtacaggtgg ttttgaagga aagaagagtc cgtccattac gccttcttcg ttatagatga
     9901 cacataccgc agtgacgggc gaacagttcg aaccaatagt gggaaaggtg aagactggtt
     9961 tagctagttt ttcaccaatg acttttacag tatcgcaagc acggccacca ccgactgcaa
    10021 acaggacgtc tgctttttgg acactttcat gctggatcaa ctgttcaata tttccataag
    10081 ttgaattacc cccgtaccag agactggcga caacctctat ttcctgtgtc aaagctactt
    10141 ttattttgtt ttctgccttt gaaagtgcag tcttccctcc aatcagcact acttttgtcc
    10201 catattcttt gacgattcca tttgcttttt catacgcatc tgttccaatg gtataatttg
    10261 gtaagaaaac actttgactc atattcattt ccttctttct tcgttgaaac gggttaaaat
    10321 tttaaagagt gatcgatctg actgcggctg tagatggagt agaggtgaac ctaagacagg
    10381 ataagtgatg aataaggtgg catgaacacc ttgaaatcat caataagtat cctaaaaacg
    10441 aacaagtaca aaaacattga aaacgacaat aatgaatttt tgttcctctt agtatttcta
    10501 ccgattccct ttgctttttt gtaattatct aaaaattcta aaaattaaga ttattatatg
    10561 aaaacaggtt ttatttgtca attcataatt ggtttttttt aaagcaaaag ataatctata
    10621 tcatgatgaa caaacagagt tttttcctcc aattgatggc tttcctgatc tttcctattt
    10681 tgaataaagt gtttctgtat aattttttta ttttataagt aagataaata atgaaagaat
    10741 agagatactg attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga
    10801 ctgttagaat aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa
    10861 taatccagta ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata
    10921 tggagacagc tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc
    10981 agcggtagac caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac
    11041 aggttgggaa ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac
    11101 tcgattagtc aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt
    11161 aggtacggat gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac
    11221 atttgataaa gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa
    11281 attaggttat aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat
    11341 ttggatggca aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac
    11401 agaagtaatc agcttcaaga aataagaagg aatttacgaa aattacttct tgaatttttg
    11461 tgaaattcca acttatttcc gaagaagcta cttttggaac accgtgtac
//
LOCUS       DAFELK010000076        10760 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFELK010000076
VERSION     DAFELK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.079"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(59..1042)
                     /gene="istA"
                     /locus_tag="LP433_002542"
                     /pseudo
     CDS             complement(59..1042)
                     /gene="istA"
                     /locus_tag="LP433_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1437..2279)
                     /locus_tag="LP433_002543"
     CDS             complement(1437..2279)
                     /locus_tag="LP433_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2006664.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2604..3020
                     /locus_tag="LP433_002544"
     CDS             2604..3020
                     /locus_tag="LP433_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2006665.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3017..3487
                     /locus_tag="LP433_002545"
     CDS             3017..3487
                     /locus_tag="LP433_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2006666.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3501..4274
                     /locus_tag="LP433_002546"
     CDS             3501..4274
                     /locus_tag="LP433_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2006667.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4288..5100
                     /locus_tag="LP433_002547"
     CDS             4288..5100
                     /locus_tag="LP433_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2006668.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5154..6119
                     /locus_tag="LP433_002548"
     CDS             5154..6119
                     /locus_tag="LP433_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2006669.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6256..8979
                     /locus_tag="LP433_002549"
     CDS             6256..8979
                     /locus_tag="LP433_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2006670.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            8992..9624
                     /locus_tag="LP433_002550"
     CDS             8992..9624
                     /locus_tag="LP433_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2006671.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            9829..10056
                     /locus_tag="LP433_002551"
     CDS             9829..10056
                     /locus_tag="LP433_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HBL2006672.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10125..10391
                     /locus_tag="LP433_002552"
     CDS             10125..10391
                     /locus_tag="LP433_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL2006673.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10381..10650
                     /locus_tag="LP433_002553"
     CDS             10381..10650
                     /locus_tag="LP433_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2006674.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         3566 a         1716 c         2102 g         3376 t
ORIGIN      
        1 aataaatagt ttttctatca agtatattga actacgataa atttgttatt ttgttttgtt
       61 taatttcgtt gtacttattg gctttgactt cgatttcttt aaatactggg taatcggtgt
      121 ccggcaaagc tagcaaatct gttttttctg tgttccatag atcattgata atgacatgtt
      181 tttcgtaatg gattcgctct cgatcgtgtg acagctccac cgctaatgcc tcgttgaaac
      241 tggcgaaatc cttcataatc ggtgtagatg aaaagaagtt gtaccgtaca tagccgactt
      301 tgttttccat actacctttc tcgtttccgc tacgtggatt gcacacctgt gtctcaaaac
      361 catagtgcat agaaaatcgg aggaaaccgt cagtcagcac cgcttgttca gtctttgttt
      421 ttgtctaagt aacggccgtt gacatattat caatccgtat tttccgagga acgccacctg
      481 attggctgaa gagttctttc atgccttcca acaaacattc ttgattctcg gcggggagta
      541 caacggcgaa tcctgcatta ctaaaaggga aagtcatcac taataccttc acatctttaa
      601 acgctccatc gtgacaaact tccatcgtac caaaatcaag ttgcgcttct gctggcgggt
      661 gttcaagacg ctcaaagcct tggtcttcca gtgtttccaa gtagtgtgtc gctttccaat
      721 cttgaatgaa tacacagact gttcggtagg atcctggaaa gccatcggct tttaaagcag
      781 tagtcattgc ttcagcagtc ctacgctttt tatttggcag cttagcatct tctgaaagcc
      841 atagggaaac gatgcctccc cacttttctg tatacatcat accagtcttt ttgcgtgctt
      901 taggttgcgg cagcaaatca tcatctgcat attttttagc cgtgcgccaa tttacatcta
      961 gctcctttgc aatatgatta atggatttat catgattatt tcgtaaattt ctgatagtat
     1021 taatatcggt cattgtgagc atacctttct tacctccagt tacagtgtcg agactataac
     1081 tttagaggag tttcaggttg cccgcaatgg ctttttatct taacttaatc gatttgcgga
     1141 gttgtgtagt ttttcgttgc acttgtatgt acttttattc tgccataaac agcttaatga
     1201 atgtccactt gaaaaagtga ataaacgaaa tagatgactc gatttaataa ggaagtaaac
     1261 ccacacagaa atataggtga ttttccttga atgaccaaga tattgaaagt tagtgaaaaa
     1321 acacaaaaag gtagccctat tcacagaagg tctgcctttt gtgttatcgc cagcaaacat
     1381 tagagggggt atttcatata gcttttgtcc tctcgacagt cctatcagtt tctcttttaa
     1441 cttatctcta agtgctgtcc agttttaata gcttctagct tgtttcctaa ctgtgttttt
     1501 aatatgttga aggcttttga acctgtgcag tggcaagtaa ggattttttc tactcgtgag
     1561 tcattcaatt tatttccaat tttcattacc tcttgctcag gtagacctaa attatttata
     1621 taaggtatgc caatcatatg gaagccacca attaggtatt ttatgggttt agtcggaaat
     1681 gtttcaagag caatttccat catatcgata atgccatgat gactacagcc agtaaagaca
     1741 atcagaccgt cttcttgctc aattacgacc aataattcat ctgaaaaatc atcataaaca
     1801 aatttatcat ccatcttttt gtataaattc ttggtggtcg agtttgcttt gcctaggggg
     1861 atgatatgga agctcggagc aagttctgtt ttcgttttta ttgtatgtaa attctcatgc
     1921 attttaagga tttcattttt aggaatacca acatacagaa acgtggttaa aatctttaaa
     1981 taatggggta aagttacacc ttcagctgta taaatagggg cgtttcctga ttttaaatat
     2041 cttaacccgc cggtgtggtc agaatgaccg tgtgaaataa tcactgcctc cagatcattc
     2101 aaagtttccc ccattttagt cgcattatag actaattttt tattagcgcc agcatcgaag
     2161 agatatttct tccctgagta gttaattaag agagataacc catgtccact tttaaagttc
     2221 aaatttattc ttgagttttc aaataaaacc ttgatttcca ctataacatc tcctttcaca
     2281 tgaacgtgta ttcatatatt gtagcacatt aagttctatt ttttgttgta attaccgaaa
     2341 aaaatattaa tggacgcttt ttacgcttta tttcgtatgt ggaagaaaat ttcttaggat
     2401 gtggcggggg attggggcaa agctaaattc caattacagt gatcatttaa ttagacacct
     2461 ttaaataccc acactttcat caacactata atttagggaa agaaaagtgt tggcatgata
     2521 tagaaaaacc tttaattaac agcgtttcct aaaattggca cgcatcttgc ttatagaaaa
     2581 gcgtaaggat aggaggaatg aaaatggcaa ctataattct tgccagccat ggggaatttg
     2641 ctcaaggatt aaagcaaaca gcgacaatga ttattggaga tagtgtacca attcatgcct
     2701 tgtcagcatt tagagatgaa gatgaatcta ttttggtaca aataaaaaaa cttttagcca
     2761 caatagatat agaagaaacc tacattttaa ctgatattct aggtggtagt gtgaataatg
     2821 atatgctcac tattattaaa gagtatgagg gattgcaatt aattactgga atgaacttac
     2881 ctttagttat ttctattgca acctataatg gaaaaattgg ggaaagtgag ctagaaaagc
     2941 ttattaaaga gagtcaacaa tcagtgattg attgtagaaa attattagta gaacaactta
     3001 ctggaggaga tgacctatga ttaagttagt acgtattgac catcgtttgt tgcacggaca
     3061 ggtagtattt tcttggagta aatcattaaa tatcaatcgt attattattg ccaataaaga
     3121 ggcagcgaat gatgaattca aaaaaatgtc tttgaattta tctaaaccga ctggcattaa
     3181 attaacaatt ttttcagttg aacagttact agaaaaaatg cctaaaatcg aaacacttaa
     3241 cgaaaatatc atgcttattt ttggtaatac aaaagaaatt cgtcaatttt gtgaagccta
     3301 tcctaaagta caagaaatca actatggagg gataatcaaa aaagaaggtt ccaagcaatt
     3361 tagtaatgcc attttcttga atgaatctga gcaagaagat gccaaaaaat taaaagctct
     3421 tggcattaaa caatttattc aacaggtacc aacttctaaa aaagaagatt tgaatacaat
     3481 gttataaagg aggaatgaaa atgctcgttc agtcaattgg tttagggtta atcggtgttt
     3541 tttgtatttt agactcaagg cttttaggaa gaatgaattt tgaacgaccg ttgattgtca
     3601 gtacgcttgt tggtttggta cttggagaca tggaaaaagg attaattgtt ggagcctctt
     3661 tggaattgat gtccttagga ttagtaaata tcggagctgc ttcaccacct gatatgaata
     3721 tggcatcaat tattgctaca gcctttgcca ttttatcaaa tgcgaatgca gaagcagcat
     3781 taacgattgc cattccaatt tcagtgttag gtcaaatact aggtatctta atgcggacga
     3841 ttttgtcaaa tttgactcac gttgcggatc gctttatcga acaaggaaaa tttagccaag
     3901 caaggagaat tcatatactt tatggctcgg gattatatgc tctcatgtat tttattccta
     3961 tttttctagc aatttatttt ggaacgaatc ttgtttctca gattgttgat gcgattcctg
     4021 agtggctaac aaatggctta acggttgcaa gtaaaatttt accagcatat gggtttgcgt
     4081 tgttattaca aacgatgtta acgaaaaaaa tggtgccatt tttattactt ggatttttaa
     4141 ttactgctta ttctggattg ggaatcattg gtattgcagc cttcgcatgt attgttgcgt
     4201 ttgtcatggt tcaagttcaa ggtaaaaact caaatggtaa ccaaaatgag ccagatccat
     4261 tagatgactt ataaggaggt agattaagtg aaagagaaag atcaaaatgc atggaaatat
     4321 cggcagttct tatggcgttc atgggcaatt caagcctcat ggaactatga acgacaaatg
     4381 aacatgggtt ttatgtacgg aattgcacca attctagata acatttacaa gaatccagaa
     4441 gatgaagcaa tgaagaaaga agcttacgag cggcatatga tgtactacaa ctgtacccct
     4501 caaacaagtg catttgtgtt agggttaact gcttctatgg aggagcaata ctacgaagac
     4561 caagaaaact ttaatccgga atcaatcagt gcagtgaaga cttctctgat gggaccgcta
     4621 tctggtgttg gtgattcttt ctttcaagga acgattcggg tattagcctt tggactagga
     4681 attaatttag cccaacaagg tagtatttta ggtccaattc tagcaatgtt aatttccttt
     4741 gtaccttcct ttttagttac ttactatggt gggaaaattg gctataacat ggggaataaa
     4801 tacttgtcta aactgtatca agaaggtttg atggataaag taatgtatgt ttgctccatt
     4861 gtggggttga tggtcattgg ttcgatgatt gccagcatga tcgggattac aacaccaatt
     4921 caaatgggta aagcttttgt cttacaagat gtattagata gtattatgcc acaattttta
     4981 ccattaggat taaccttctt catgtactgg ttattgcaga aaaaggtcaa aacaggatgg
     5041 atgttggcaa tctgtttagt cggaggaatt atttttagtt tgttaggtat cttacaataa
     5101 gggaataacc aataaatttg gttgaataat ataaataagg aggaattcaa ttgatgaatt
     5161 caaaagaaat tgttaaagaa atcgtagcga aaaaagaggt aaaatcaatc gtatttgttg
     5221 gctgtggcgc ttcaaaagcg gacctttatc ctgcaaagta ttttctagac caaaatgcga
     5281 agcagttacg gattagtcat tacacagcca gcgaatttaa ctatgcaaca ccagcatctg
     5341 tagatgagtc aactgtcgtt atttcagctt ctttaggagg tacgactcca gaaacagttg
     5401 aagctaacgc agtagctaaa gaaaaaggtg ctacagttat tagtctaaca cgaagcattg
     5461 actcaccgtt aacaaaagat gcagattatg taatttatca tcgatttgca gagaactatg
     5521 ctgctaaatt agaaaaaaca ggctactgtt tagaattggc agtagaactt ttacatcaag
     5581 tagaaggtta tgaccattat gaagcaatgc aagaaggatt tgctactatc tatgatcttg
     5641 cccaaaaaag tgcagaatca gctcgtaaag atgcgaagaa atttgctgaa cgctttaaag
     5701 atgaaaaagt tatttatgta atgagtagtg gtgctacaca tgaagtagca tactcaacat
     5761 caatttgctt gatgatggaa atgcaatgga ttaattctgg taccttccat tcaggagaat
     5821 ttttccacgg accattcgaa attgtggata aagacgtacc gtttatatta ttaatgaatg
     5881 atggaaaaac tagaaatata gatgctcgag cattaacttt ccttgaacgc tttgatacga
     5941 aaacagaagt tgtagatgcc ttggattatg gcttgtcttc acatattgct aaagaagtct
     6001 tagactactt taacccattc gtgattactg cagtatttag agtttatgca gaagaattgt
     6061 cagaagcaag agaacatcca ttaactaaga gacgttatat gtggaaacta acttattaaa
     6121 aaatagatca aactaaataa ggtggcttga gaaattaagc caccttgttt tcttcaatgt
     6181 gattttatac atatggtaaa ataactagta catatggtaa aataactagt acatattgtg
     6241 aaagcaggtg gcaagatgca gcgattaaat gactatcttt atcaactaac attgcttttg
     6301 aaatctacgc cttcagataa ttattcagct cgcagtattt cgcaagctct acagttgaat
     6361 agaagtacaa tcagtagcta cttaaatgaa ggtgttcgtg aagggctttt cataaaagta
     6421 aaaagttacc cggttttatt tttacataga acagctcttg aagaactaca tatcacactg
     6481 aataactccg aaatagaatc aattgaaagc ttgttaacaa tttctcaaaa acccgcatta
     6541 gatcaagtaa ttggctctaa aggaagtttg aaagaagcaa ttgatcaaat taaaacggca
     6601 gtcttatatc ctggaaaagg gttgccttta ttattgatcg gcgctagtgg atcagggaaa
     6661 acctttctag cgaataaaat atatgaatat gcagtagaag aaaaggtcat tcacacatcg
     6721 gcacctttca tagattataa ttgtgcacaa tatgtgagca atccagagtt actatcctct
     6781 gctttatttg gctacacgaa aggagcattt accggagcaa gccaggagca tactggtttg
     6841 ctagaaaaag ccgatggagg agtattgttt ttagatgaag tgcatcgctt atctgaagaa
     6901 gggcaagaga aattatttac atttatggat acgggtgaat tctctcctat gggggataat
     6961 agtattcgga aaaaagccga tgttcgatta gtctttgcaa caacagaaaa tatatatacg
     7021 actttcttac caacttttct taggagattg ccagttattg ttaatctacc tagatttcaa
     7081 caacgtccgt cgtttgaacg tctgtcattg attgatgaat tttttgtttc tgagagccaa
     7141 attttagcta aggaactatc tgtttctgat gcattgattc atttcttaat gaatagtgat
     7201 tttgaaggta acgtggggaa tattaaaaat attatcaagt atgcttgcgg aaacgcatat
     7261 atccaccaga agagtcagca aacaattcaa gttaaattat tggatatgcc tttagagtac
     7321 agttataaat tcaaggagca actaaataaa cccagaaaga aaagagcaga tcgaatctac
     7381 tatccagaag aaacacgaca agtgcaacta gaaagaaaca atcagctttt tgttcaattt
     7441 tttgaccaat tacttactgg attctctgaa gtgattgaaa ataacaagga tattaaacta
     7501 tttttagaag aaatggttac caaggtaaca caagtaatgg atacgcttat ttttcaagag
     7561 gattacgaaa aagagcagtc tttatacgcc attctaaact atcatattcg tcaaagtatt
     7621 gattttatgc gagaaagcta cgggtttgaa caagatggta accgggtagt cgctttggcc
     7681 aactatctat atgtcaagga taatcaagtg atttttgaaa atagtcttca agaaaagaaa
     7741 accaaagatc agcttaacga attttttgct aatgttcttg aaacccctta ttggtatgca
     7801 aaaaaaatct taagcctttt atctgagtgt ttagatcaac ctgtgtatga agaggacatt
     7861 ttctttatta cgctatattt ttatagtttg aatgtcacga atgttaaaac aggtattaag
     7921 agtattgtgc tagctcatgg ttattctaca gctagtagta tggcgaatgt tgccaaccgt
     7981 atgctgaata agaacgtttt tcaagcttat gatatgcctt tagatattac attagagaaa
     8041 attgaagcaa aattgattca attccttgga gattatcgaa cagattcagg cttgatttta
     8101 ttggtagata tgggttcact aaaccaacta ggcggtttat tagtgaatca tctaaatgga
     8161 ccactgttaa tcattgatca tatcaataca ccgttattat tggaagtcgg ccaacaagta
     8221 ttaaacaata aaagtatcac cgaaatagga gcagaaattg aaacaagtct tactttcaaa
     8281 aagcagttac tacttcccaa gaaaaagaaa aagaaagcca tcattacttg ttgttataca
     8341 gggattggta gtgcgaccca gattcaggag attttaacga aatgcttgaa agatgcagtt
     8401 agagaattag taattattcc gtatgattac aaaaagctgt tagaaaacaa gaattttgag
     8461 actccttttc aattatacga tgtcatcatg attgtaggta cagaagatcc caaaattaat
     8521 cagattccat atattggatt agatcgcctg attaatgggg gaagcattgg cgaatttgtt
     8581 cattacttgg aaaaagagct gactattgaa gtgaacgatt tacaaaaaga attaattttc
     8641 aatttttcaa ttagtaaaat tgtcgaaaat ttaaccattt tggatccaga taaggtgcta
     8701 tcttttgtac aaaaagcaat taaagaatta tcgaagttat taaattttga tttttctaat
     8761 aatcagctgt ttttgttgta ccttcactgt agttgtatga ttgaacgaat tgtacgtaaa
     8821 gaaagtgtgg atgagcaaga ggacattgaa gaatatatgc aagcaaatgg agaaataatg
     8881 gataaaattc atagcgcttt ttttgagatt gaaagggaat acacaattga aataccagat
     8941 ttagagttgc gattattgag cgatattgtt caaggatagg agtgaattcg aatgacaatg
     9001 ggagtaattt ttgatatgga tggggtactc atagatagcg agacatttta ttttgagaga
     9061 agaatgaact tctttcaaga actggagata gatccaggat caaaccagat tgatgattat
     9121 gtggggaaaa cagaagctgc aatatgggaa acattagttc ctgaggacaa atcattaaga
     9181 gaggaacttt atccgaaata tgtagattat cgaaaaacgc atccaattga tttcgctaaa
     9241 gctttacgaa aagaagtgaa accgttactt gacttcctca agaagcggga tataccattg
     9301 gcactggcat cttcttctcc agctgtcgag atagagagta tgctcattca atgtgaactt
     9361 actgaatatt tttcctttgt tataagtggt gagtcattaa aacaaagcaa accacatccc
     9421 gaaatatatt taaaagcgaa acagcaatta gactgtgact tctttattgc agtagaggat
     9481 tcaacgattg gtattaaatc agcaaaggca gcaaatatct atacggcggc actaaaacaa
     9541 ccaatgcaaa tcgatcagag tgaagcagac atacaaattg aaagtctaca agaactggaa
     9601 caaattgttt tagaaaaagg ttagtgaatt aatggaaata aggctatata tctgtgctag
     9661 ctattttgac taaccaaaaa aacttgctat aattcaggtg tagtaaaagg tgctggtaac
     9721 accttttacg aaaatgcttc ggcagtgata atgggattgg ctttttaagt tttttatttt
     9781 gttcgcaatc cctaaggtca tgtgaatgat cctagggatt gctagaatat tttgcaacag
     9841 aaccaaaata cgaatagtta tcaagcagcc atattgactg cggtcaattt aggaggggat
     9901 actgatacta ctgctgccgt aactggtgct cttgcgggta ttctttacgg gggtgaagtg
     9961 atccctgaaa attggagaaa atcgcttcaa aatgaccagc ttcttaaaac gatcagtcag
    10021 agattttgcg ataccgtgct atctcaaaga atttgaataa tggatatgat gcaaatcttg
    10081 tttgtactaa cgttgtattg acaaaaagga ttttatttag tacaatgtta gtacaaatga
    10141 tgaacggagg tagaatcatg tctcaatcaa ccattacatt taggattccc gacgatgaaa
    10201 aagaactggt attagaatat gcaaaagcac acaattcttc attgaccgaa ctttatcgaa
    10261 atgctgtact ggataaaatc gaagatgaaa tcgatctacg gactttacgg agtgcaattg
    10321 aagtttccaa agagaaaaaa gagagtggta tttctcaaga ggaaatggag aaactgctaa
    10381 atgaattata aagtcatcta catgccgcaa gcccagaagc aattaaaaaa aatggacaga
    10441 aaccaagcta aaataattgt cgcctggatc agaaagaatt tagaaaacac gactgacccg
    10501 cgtcagcacg gaaaaggttt gactggaaat aagagtgggg aatggcgcta tcgaattgga
    10561 aactatcgaa tattggctaa tatttgtgat tctgaaattg aaatccagat attctcaatt
    10621 ggacatagaa gtacaatata taaaagataa ccgtttttgg aacgaagtag agtttcgaaa
    10681 gtcaatgtat aatcttttga attttgcata ataccacagg tagaaactac ccgatactat
    10741 cggttggttt ctgctttttt
//
LOCUS       DAFELK010000077        10617 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFELK010000077
VERSION     DAFELK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.080"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            289..2235
                     /locus_tag="LP433_002554"
     CDS             289..2235
                     /locus_tag="LP433_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2006675.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2238..2693
                     /locus_tag="LP433_002555"
     CDS             2238..2693
                     /locus_tag="LP433_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2006676.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2707..4035
                     /locus_tag="LP433_002556"
     CDS             2707..4035
                     /locus_tag="LP433_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL2006677.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            4069..4353
                     /locus_tag="LP433_002557"
     CDS             4069..4353
                     /locus_tag="LP433_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2006678.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            4355..4870
                     /locus_tag="LP433_002558"
     CDS             4355..4870
                     /locus_tag="LP433_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBL2006679.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            4886..5548
                     /gene="rpe"
                     /locus_tag="LP433_002559"
     CDS             4886..5548
                     /gene="rpe"
                     /locus_tag="LP433_002559"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL2006680.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            5555..6127
                     /locus_tag="LP433_002560"
     CDS             5555..6127
                     /locus_tag="LP433_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2006681.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(6314..7834)
                     /locus_tag="LP433_002561"
     CDS             complement(6314..7834)
                     /locus_tag="LP433_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL2006682.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(8077..8262)
                     /locus_tag="LP433_002562"
     CDS             complement(8077..8262)
                     /locus_tag="LP433_002562"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL2006683.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(8246..8428)
                     /locus_tag="LP433_002563"
     CDS             complement(8246..8428)
                     /locus_tag="LP433_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006684.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            8669..8887
                     /locus_tag="LP433_002564"
                     /pseudo
     CDS             8669..8887
                     /locus_tag="LP433_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9382..9981
                     /locus_tag="LP433_002565"
     CDS             9382..9981
                     /locus_tag="LP433_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2006685.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            10045..>10617
                     /locus_tag="LP433_002566"
     CDS             10045..>10617
                     /locus_tag="LP433_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HBL2006686.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT         3509 a         1670 c         1983 g         3455 t
ORIGIN      
        1 ttataataaa aaaatacgaa ttttagtgac gccattatat tgtttttatt tttcaattgt
       61 aatatttcat attacttcca taataaggag tattttctat tggaatatct tagctctttt
      121 aaggatttct ccttttttgt ttctcatttt ttaagattat ttggatttcc tttacaacaa
      181 acttccacaa gtattattga catagatgta attgagggaa gggggttcca gtgctagaat
      241 aaataatgaa aagaggtaac aaatgctagc gttaagaggt gaacaagttt gattgaaaga
      301 catgtaaatt tattaaaatt attaagtcga caagaagact ttaaacccgc ttcttttttt
      361 agtgataaat tggcagtgtc gaccaagacc atttatcaag atattgaatt gttggaagat
      421 tatgtagtta attaccaagt aacaattgag cgattacctt ctttgggtat caaactcata
      481 ggtgatagga aaaacgttga acatttgatt tcatcggtag aaaattatct tgaaaaagat
      541 atttattctc cagaaaaaag acgtgtcgag atcattaaag aagttttgtt tggtgataag
      601 cctgtttctt taactcattt gtctcaaagt tttatggtta gtaaaacatc gttatacaat
      661 gacctgagaa ttatcaataa aattattggc agtggagaag ttaagttgca gtcatctgca
      721 gaaggaatta gttttactgg taatgaacaa gcaattcaac gagcaatcaa gcaacttgta
      781 ttctattatg cgaatgacat ggaatcaaaa acattttttc aagttttaaa tatgttgttt
      841 gattcaaaag ttattagtgt cattcatgat ttgctattca atgattacag tgaactgact
      901 gaaaaggttt ctgattacta tgttcggtca ttgatttcta ctttagttat ccaatgtaac
      961 cgtttactga aaggtcatca tttaactgtt gaagaagaat tcctcttcaa tagcattcgc
     1021 tatatggaaa cgtacattgt ggcaaatggt ttaattgaag aattgaaggc aaaattgaat
     1081 cttccatttt atgacgcaga taaagaatat ctatgtcgtc aactatttgc acatcgtgtg
     1141 acaaataatt taaaaaccag caatgaagag tacgctatga gcgttcataa attgattgaa
     1201 agaatgagtg agattgaaaa aattgatttg actcaaaatg atcgattata tcaatcctta
     1261 ttgtatcatg tgccagcaat ggtccttcgt ttaaaaaaag gtattaaaat tcaaaatccg
     1321 ttattagaaa atatcaaatc tcaatattca gaactcttta gcatagtatg gtacgccatg
     1381 tccatccttg aagaagaatt tgatgtgact ttaacggacg atgaagtttc cttaattttg
     1441 attcattttc agattgctat tgaagatcag tccaaagcaa ataatatcat cattatttgc
     1501 caatacggta tttcttctgc gcaattaatt tacaataaag ttcgacggtt tttaccagca
     1561 aaagataatg tagaaatatc aactttagat aagtttcatt tagctgaaat tggggaagtt
     1621 gatttgatta tttcctctct ttcctttgat gcaggtggta tacccttagt aagggtatct
     1681 ccattggtaa gtaaaacaga ttatatgaat attatggaag cttatactaa atatttaata
     1741 gaagaacctt cgcgatttat tcaaaatgaa ctgattccta aagcggttaa agttcccacc
     1801 atatctaaat ttgttcaatc atctttagta aaaacaggag tacaggtgga aagcaaagaa
     1861 gaatgtttgg atttgatgat ttccgaacta gaagccaatt cattagttac tgaagagttt
     1921 cgtgcttcta tcttctctag agagaaaatg gggaatacta atttagaaag tggtgttgct
     1981 ttaccgcatg cgaatccatc aatggtcatt gaatccaaca tttttattgt agcattaaaa
     2041 aatgcgatta attggggcga tcgaaaagtc aaattagtca ttatggttag tttagctgaa
     2101 gaagatgtat ctgagattag aggagtatat gaagaacttt accaatttat tgggcaaaaa
     2161 gaaatggtcg atcgcttgtt acaagttcat gatagcgaaa aattactaag aatttttcaa
     2221 caaaaaggag aataaaaatg tatctagata aagaattatg tttatttcaa ttagaagtga
     2281 aagatcaaaa agaattgttt caagtaatgt ctgaacaatt aaaaaacgct ggttgcgtga
     2341 aagatagttt cttagaaggt atcaccaacc gtgaacaaga atttccaact ggattagaag
     2401 taaatcaaat tgggtttgct atcccacata cagattccgc acatgtaaat agctctcaaa
     2461 tctgttttgc ctcattaaag gaaccactgg tattttcaga tatgacagat aaatctcatg
     2521 aaatacctgt acgtttagtc tttatgttgg caatgtcaca acctcatgaa caaattgata
     2581 cactacaaaa cttagttagc ctatttcaaa atgaagaaaa agtaaatgaa ttacttgcat
     2641 gtaccacgaa agaagcattt attgagttag tacattctgc aggagtttat taggaggaat
     2701 agagagatgg atattgtatt aaatgccttt gaatggttta ttggattagg gtcaaacgtc
     2761 tttttaccac tgattatttt tgtaatcggg atattatttg gattaaaacc tggtaaagca
     2821 tttgtttccg gcgttactgt tggtatcggt tctattggtt taggattagt tttaagttta
     2881 ttatcagatg gtttaggaac agcaattcaa caaatggggg aacaatacgg tggtggcctg
     2941 aatatcctag atattggcgt aggtgttggt ggacctttgg cttactctac atcattggga
     3001 attttaatga ttccaatttc attaattctt aacttcatat ttgtggtttt gggttggaca
     3061 aaaacattga atgttgatat ttggaacttt tggttcgcaa ttttcctagg tatgattact
     3121 caatctgtta cgggaaactt ttggtttggc ttaattggcg cgattgtcgc agtaatttta
     3181 caatggttct tagcagatcg tacacaaaaa actgttagcg aatttttcgg ctatccagga
     3241 atctctatca cacatatgat gggattatca ggagtactat ttgccaaacc agtaaattgg
     3301 gtttttgatc gtattcctgg atttaataaa atagatgcag atgcagaaac attaacaaaa
     3361 cgtttcggtg ttttaggtga cacagttgtt attggcctaa ttatcggtat tgtagtgggt
     3421 attatggcag gctatgacgt agcaggaatt ggaaacttag gaattatgac tgcggcagtg
     3481 atgaagatta tgcctaaaat ggtagcaatg tttatggaag gtttaatgcc aattgcagaa
     3541 gcggcgaaag aatttacgaa taaaaagtta aatggtcgcc aagtaaacat tggaatggat
     3601 gcagcgttaa ctgtgggtca tccaactatt atgtcaactt ctctattgct tgtaccaatc
     3661 tcattattgc tagcactaat tcttccagga aataaagtat taccttttgg agatttagca
     3721 ttctttgctt tcgccatctg tttaatgatt ccttatttta aaggaaatat tgtgagatca
     3781 ttagtaggat gttcgttgta tgttgttaca acattatata tggcaacatg gttggcacca
     3841 attatcactg atgtgtttac attagcaagt ttcgatgtgg ggacagcagg attagtaact
     3901 atgttgttat gtggattatg gccagtaggg ttgtttgttt tattagcatc ttactttggt
     3961 gtaattggaa taggtggatt aggagttgtt ttagtaggtg cttctatcta catgaacaaa
     4021 gtgaagaaag cttaatcata aaattaaaat aagaaagaag agatcaatat gaaaaaatta
     4081 ttagttattt gtggagcagg tcatgctact tctacaattg cagtagcaaa attatcaaaa
     4141 tggttggaag aagaaggatt aacagatcaa gtgaaaattt atcaatctaa aattgctgat
     4201 gagctaaata aaattgatga atatgatgct gtagtaagta caacaattgt ccctgatgta
     4261 attaaagcta aagtaacgaa tggcttgggc ttattaacag gtattggtac agatgccatt
     4321 tatgcagatg taaaagaaag attaggtgtt taatatgcgt tttcatcatg acactttgac
     4381 tattgaaaca gtttcagggc gtccttcgta tcatgatatt cgaaaagaac ttttagatac
     4441 agttgataca gcaggtattg agaatggaat gttagtaatt tcgagcccgc atacaacttg
     4501 ctcactcttt tttgaagaaa cgatgcatga cacaaacttt tttggtgatg attatttaca
     4561 tgtagacatc aacaatgtaa tggaaacgat tattccaaaa atgacgagtg aaaatcaata
     4621 caacagtccg gggccaaaac acattgattt tggaacaaga ttatctgatc ccaattaccc
     4681 tgcagaaaaa tgggtcatgc taaataccga tgcacattta cgttcatcta tttatggaac
     4741 caactcaatg actttaattg ttcaagaagg taaactttta ttaggagaaa tgggccgtgt
     4801 ctattttgtc gattgggatc aactaagaga gcgaactaga acaatcaatc tcatgattat
     4861 gggagaataa acgggggaat agagaatgac aattgctcca tcattgttaa atgcacctat
     4921 cgcagaagtt aaagagttat ttgaaatctt aaaagaaaag aatgttgatt atttgcatat
     4981 tgatgtaatg gatggctgtt ttgtaccaga tatggctttt ggaccaagtg ttattaaaga
     5041 tattcgtcca ctaacagacg ttgtgtttga tgttcatttg atgattgata caccagaaaa
     5101 aattgtcaca agatttgtag aagcaggagc agatattgtt accttccaca ttgaagctac
     5161 caaacacgca atgaaggtca ttcagttagt caaggaagca ggagcaaaag tagggattac
     5221 ttttaatcct gcaacaccag tcagttttat tgaaccagta ttatctttag tcgatcaagt
     5281 attagtaatg acaatcaatc caggaacaga gaataagcat tttattcaag agacagtagt
     5341 taaaatcgaa cagttagatg taatacgcaa acaaaatgat tatacgtatg atattgaagt
     5401 agatggcaag attgataatc aaacgattaa agtttgttct aaagcagggg cggatatttt
     5461 tgtatcaggc ggtttcatct tcaatgggaa aaataccccg caagaacaaa ttgataaact
     5521 aaatcaatca ttagaggaag tgaagtaaaa gatcatgacc aataaagacc aaaataaaaa
     5581 ctatttagaa gcgattatct tagaattaca aaataactca aaacgtatta attctgtaga
     5641 gttagaacaa tttagtgaga aaattgttca agctaaacac atctttctag ctggtgcagg
     5701 acgctctgga attgccatgc aagcatttac gaatcgctta atgcatttag gtttttcagt
     5761 cagccttgtc ggtgaaatta gttcaccaca ttcgcaacct ggagatttat taattatctg
     5821 ttctggctca ggtgaaacag gtagtttaaa aaatttagcg gccaaagcaa atcaaagtgg
     5881 tgtaagcatt gctttagtta ccatgaaaaa agactcgtcg attggtcaat tagcagattc
     5941 tgttcttgta ttaccaggta ttaccaaaga tgaaaatcaa cgagaagaag atactttttc
     6001 acaacctatg ggttcaagtt ttgaacaatt agcatttctc acctttgata gtttagtgtt
     6061 atctttaatg gataaaacag gtgaaagctc agaaacgatg tttgctcgac atgcagattt
     6121 tgagtagtag attttaaaga taaaaaacca ttctctaaat gctaattatt cagcaaatat
     6181 gagaatggtt tttttatttg attagacata acttaataat tcagtagttt tgagcgtaag
     6241 cgtgtcatag aatggtacct aaacacaaat agcccgattt gatacactca aatcaggtta
     6301 tttgtggctt atattattta cagatttctt gtatctgctg attccatggc aaataagcgc
     6361 gtagcgcttc aggtgtcatc gaagacagat tgggaatctc tgtaaaaaga tgatttaaat
     6421 atttgcggat gtttaaccca ttcgcaacag ctgtctggat aatactcaat ataattccat
     6481 ttgatctagc gccttttaag cttttagaaa atagccagtt ttttcgaccg atcactaact
     6541 ctttgatggc acgctctgct cggttatttg aaagttccaa gcgtccatca agcaacacaa
     6601 tctgaagtcc gtctttatga ttgactgcgt attgaaccgc ctttccaagc tgcgattttg
     6661 gcaaataagc aaaactctca caccaatgaa aaaattcagt catcacaggc tgcaacgttt
     6721 ccttcctcgc tacaaacctt tcttctgcgc taagcttatt aaaggtccgt tcgattcgaa
     6781 acatcttgtc acagaagtct aatcctattt tggcatgact ttttggggac ggttgtttac
     6841 ccaatgcttc aaaaaacttt ctgcgaacat gcgcccaaca ataaacattg tttaccggca
     6901 gctttccata ggccgcgtaa ccatcagtat gcaagaaacc gctaaatgat tctaaaaaac
     6961 tttttggctc atcaacggaa cgcgaatttg cgtgctcgta gagcacaact tgtttttctt
     7021 cgcttttacc tgaagcatat aaccagtaaa aggtcttttc tttatgagta ttcaataccc
     7081 gatagcttgt ctcatccgcg tgtaagacct cctgattgct taattcttga tgaaggcaat
     7141 tgtagattgg ctctaaaacc atttcactta ccttgatatg ccaattagtg atttttttac
     7201 gatcaagagg gaaaccaagt gcatgccatt ctttttcttg tcgatatgcc ggcacctttt
     7261 taacaaattt ttcccaaata ctctgtgtca caattgaaga ggaacctaga ctattattga
     7321 tcaacggttt aggaacaggc gcttttttga tttttgtttc tcctaatgct tcacattctc
     7381 tgcaatgata ggcatgttgg tagatgactt gtttttctat atgggcagga acatacaatg
     7441 gctcttctct aagccttgtc gcaccgatat catgtaaagt atgaccacag tcttcacaca
     7501 aacaatcggc accttttaat tcataatgaa taggaacttc aggcagacct tctaatgaaa
     7561 gtgctttgag tcccttgcgt tttctgcgtt taaaagaaga taccgtaatg ggttcctggc
     7621 tttcttgtcc agtgtgctct ggttcattaa aagttgagtc gtctaataaa tcgatttgcc
     7681 catctacggg tggtgtttct ttttttcgtc caaacaagcg tcgattcatt tcagcaattt
     7741 gttctctaag aagagtattt tcctgttgct ggatttcaag caactgtgtt aattgcttga
     7801 tttgtacaag aagttcagat tccatttttg tcatttttac accaccattc tagcgatttt
     7861 cttacatcta ttataccatt ttatgacaac gaaaaacaga caaaatcctt gatttaacaa
     7921 ggttttcgtc taatatatcg cacctttttt cgtttctttt agcgtacatt tttcttcgat
     7981 tgaaaggcca gtcagtaaga cttcttttct ggaacgcggc cattgaaggt acccactttc
     8041 aaatcttttg tacattaata caaatccatt ttgatcctag taaagagcct tgaagcgatc
     8101 tttcttcgta ccgcaaaata agaaaagcgc ttgatcgtaa acatcaaggt catattcttc
     8161 tataacgaaa gctgctagtc catcaattcc ttttcgaaga tctgtttttc cacaaacgat
     8221 aaaaatatgt ttcaatgcag ttgcatcaat gagcattggc attcaactct tttaacaagg
     8281 tatacaaaag atatttatcc attccattat aaataaatat ttccttatct tccgatttga
     8341 ttctgcaagc tagttttggc ttggtgtcaa tttgcgattt ttgagccgca cttgaaaatt
     8401 gaactggtac aatatctttt ttattcattc gtttttctcc ttctatattt gatagtttaa
     8461 ttatagaaga aagataatcg gcgtacgaga tactatccta tgacacgctt acatttaatt
     8521 taatattttg cctcaaatta gccacacttt ttatagaact aagaggaaaa atgaagtttt
     8581 cttcctatta atatagttgt ttgaaatctt aaatatagcg ttttacgatg taatgggaag
     8641 tatggtgaat aaatcaacta tgttcgtacg aagcatttac tcaactaatt taatcgaatc
     8701 tttcaataaa caaatcaaga aatacagcca ccgcaaggaa cagttccaaa atgaagagtc
     8761 gatggaacgt ttcttagtct cgtcttttga tacttacaac caaaaattcc taggtcgcag
     8821 tcataaaggt ttccaacagg ccgaaggcga gctcgaacaa atgctgagtc aaccgatgga
     8881 gaattagaaa caatctacag tagggaagaa ccattgacac aaaattattg acgctcccaa
     8941 ctaaaagtgt caaaataatg atgaaatcat ttagttctta taaattagaa aagagaaaat
     9001 aaatattcca tatctacttt attggatccg taacatgact aaattctgaa tactttttaa
     9061 agcttatcat ttggtaaaac tgaatataag ttaattatat agactgaaaa ttttgaattt
     9121 tcagaataga ataacttaaa agtactgaca aaatttttta aaggggcaat attaatgttc
     9181 tgagataatc aaatcctacc gaaaatatca aaaatccaat gtgacacaat cggattgtgt
     9241 ctcattcgag ggaatcacac aatcccacgt ggctctaggc agaattgaat ttttgcttgg
     9301 ggctttttcc ttatattgat tttgaatgag acttattata tgttataatg caattaagta
     9361 tcattggaga gggcgaagaa aatgaagacg gtagaaccta ttcgagacaa aaaaaagatc
     9421 gatgcgatga aggcaatctt ggcttcggga aaatatggcc aacgaaattt ggttcttttt
     9481 tcgattggga tcaacaccgc ctatcgcatt tctgatttgc gtcaattgaa gctggccgac
     9541 gtgctggaaa tttcacgcgg tcgcgtggtg gtcaaagatc gattagcgat gaaggaacaa
     9601 aaaacagcta aacataattc ggtctatatt tccaacaaat tgcgaaaaac gattttggag
     9661 tacgttcaac aggaatttcc tgatcaactc cttcagcaag attttgacgg ttatttgttc
     9721 cctagtcgaa aagggacgaa tgaaccgctc aaccgccaaa gtctgtggcg aatcattcat
     9781 gatgctggca cggcaatcgg attgaaagac attggcccac attccatgcg aaaaacgttc
     9841 ggttactttc tctataaaca ggggaccaaa acagaaatca ttcagtcctt gttgaaccat
     9901 tcttctcagc gcgaaacatt gcggtatatt ggtattacac aagaagacaa agatacagct
     9961 gtaaaaagct tagatttata atataaaagt taagtttaaa catggatagt tttaaattag
    10021 tagattgagt gttgggagga aagaatgagt acattatata ttataggaaa cggttttgat
    10081 ttaagtcatg gtttaaaaac tagatacact gatttttcaa aatgggttga aaaaagtcat
    10141 agtgaaatat tcgataaaat agacacaatg ataaatgaaa ataatgaggt gagaagtaca
    10201 gctgatgata agataggttg gtttaatttt gaaagtagtt tgcatgagtt aattcaaagt
    10261 ccagtctttg aagattatgt agaagagtct aaggattatc tcataggtta tggacatgaa
    10321 gattggtcag attctgccca tcatgatttt caaaatatgg tttatgatta tgttgtttct
    10381 ctagaagaat tacaacaact tttcaaggaa tggatacgca aagaaataca gccgacaata
    10441 gaacataaaa ttccaaaata ccaattttcg tccgatgtac tattctttac attcaattat
    10501 acagatgttt tggaaattct atacaagcaa ccgaaagaaa acatatatca tattcatggc
    10561 agttatgacg atataataat cggccactcc gagaattttg acaactttat aggagat
//
LOCUS       DAFELK010000078        10021 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFELK010000078
VERSION     DAFELK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.081"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..722)
                     /locus_tag="LP433_002567"
     CDS             complement(<1..722)
                     /locus_tag="LP433_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL2006687.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     KPGMATVFLTNFIRCRTSFRML"
     gene            complement(727..1494)
                     /locus_tag="LP433_002568"
     CDS             complement(727..1494)
                     /locus_tag="LP433_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2006688.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1983..2408
                     /gene="lacA"
                     /locus_tag="LP433_002569"
     CDS             1983..2408
                     /gene="lacA"
                     /locus_tag="LP433_002569"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HBL2006689.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2425..2940
                     /gene="lacB"
                     /locus_tag="LP433_002570"
     CDS             2425..2940
                     /gene="lacB"
                     /locus_tag="LP433_002570"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HBL2006690.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2951..3883
                     /gene="lacC"
                     /locus_tag="LP433_002571"
     CDS             2951..3883
                     /gene="lacC"
                     /locus_tag="LP433_002571"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HBL2006691.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTVSHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3886..4866
                     /gene="lacD"
                     /locus_tag="LP433_002572"
     CDS             3886..4866
                     /gene="lacD"
                     /locus_tag="LP433_002572"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL2006692.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4894..5211
                     /locus_tag="LP433_002573"
     CDS             4894..5211
                     /locus_tag="LP433_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2006693.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5211..6917
                     /locus_tag="LP433_002574"
     CDS             5211..6917
                     /locus_tag="LP433_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2006694.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTVLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7059..8465
                     /gene="lacG"
                     /locus_tag="LP433_002575"
     CDS             7059..8465
                     /gene="lacG"
                     /locus_tag="LP433_002575"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBL2006695.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8488..8760
                     /locus_tag="LP433_002576"
     CDS             8488..8760
                     /locus_tag="LP433_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HBL2006696.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            8781..9680
                     /locus_tag="LP433_002577"
     CDS             8781..9680
                     /locus_tag="LP433_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL2006697.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3164 a         1690 c         2008 g         3159 t
ORIGIN      
        1 aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac tgttgccatt
       61 ccaggtttat gacgactttt ggaagtaaaa atccatccat tatctttata atcaggattg
      121 aatcttatat gttggtgatt taactcaatt tcctctttaa gaatttctat agccctttta
      181 gataattgga cattttggta actttgtaag ttttttacat taccttcata gctattttct
      241 gcagctcctc cgtgagtgga ctgactaatg atgatatttt gcttttcaaa atattgatag
      301 gcaccaatat tttggagttt tcgactctgt aagtcaacag ggccattagt tagaatacct
      361 attgggatgc ggtttttatg tagagccagc agtagttgat gtatctcagg aatcatcgta
      421 atctgatcga gttcatattc atagtcagct tggaagtcta gagcttctgt cctagaaata
      481 ctatcgatgc caaattcttc catagtcttc tgacagcgaa aaattctaag ctgctcaata
      541 ctgatgagtt ttttcgtgta tttaggaaaa gcaacatcag accaacatct gaaacgtttg
      601 taaatgttat ctatttgttg gatatcaatc gttggaaaac atttctcaac gctacgttta
      661 aaggggagtt gatggtcata aagagtgtca tcaaggtcaa aaacaatatt tttataagtc
      721 ataattctag tccgctttta aaatagtagt gtactggcta aattcctcta agtgttgagg
      781 gctaatctgg ttatctgtaa tgatggtatc gagttgatct agattataga agttaaagaa
      841 atcgtatcga tcgaatttag tactgtctac taataagaat ttttctacag cattgtttag
      901 ggcaagttgt tgaatcacac cttccttgtc actatatgta gcaatagaat tatgggtaac
      961 agcatttgca ctaacaaaag ctttggcaaa tctaattgct tttaaatttg tcgaagccat
     1021 tgaacctaca aaagctccag ttatttctct atattcaccg ccaagaagca ataaatcaat
     1081 ggtttcgcta tcatttagaa tcaagaacac agggagacta tttgtaatga cacgaatttt
     1141 ataaccttta cgacctttca attctaatgc cagttgttca agtgtagttc cgggtccaat
     1201 aaaaatagta tcgccatctt tgattaaaga gcaggctttt ttagcaatgt caattttttc
     1261 ttttgtattt agacttttct tctcgatatg tgtcttttca agtggctttt tagaggaaag
     1321 taattgtgca ccaccatgag tacgtgttaa aagtccatca gcttctagag catcaaggtc
     1381 tctacgggct gtcatatcgg aaatatctag ttcatctatt atttctttta tggttatggt
     1441 cccatcaatc tttaacatat ctaaaatttt ttctaatcgt cgttttttgt tcatatgaag
     1501 acccttcttt cataaagtaa tttttttcca aagataattc tcttttaatt gtatcataaa
     1561 agacaatatt ttcaaggtaa aacaaacaat ttcaaacaaa aacaaatgtt agatgatgaa
     1621 ataagaacag tggattgacg tatattagct taggtcagat tttgtataag acgaaaataa
     1681 agtaggacct cttaatcagt aagttataga aagtaaaaga cttttgtaat acttgaatag
     1741 atatttcacg tccattttgt gatggattaa atgaacaaaa atgaacaata atttaacggt
     1801 gttatctatt ttttaagaaa acaaataaaa aaaacaaaaa ataaacaaaa aagtgttgct
     1861 ttttgtttga atgattgata ttatataaac aaagaaatga tgaaaacgtt ttttcgaaca
     1921 ttttgcaaaa tgttttctac ttctacgtag catttctttc taaaatttag gaggtggtca
     1981 aaatggctat tgttgttggt gcagatctca aaggtacgag attaaaagat gttgtgaaaa
     2041 attttcttgt agaagaaggt tttgaggtaa ttgatgtgac taaggacgga caagattttg
     2101 ttgatgttac cttggcagtt gcctctgaag taaataaaga tgagcaaaac ttaggtattg
     2161 taattgatgc ttatggagct ggtccattca tggtagcaac taaaattaaa ggtatggttg
     2221 cagcagaagt ttcagatgaa cgctcagctt atatgacacg tggacataac aattcacgaa
     2281 tgattacggt tggcgctgaa atcgtcggtg atgagcttgc taaaaacatc gctaaaggtt
     2341 tcgtcaatgg taaatatgat ggcggacgtc atcaaatccg agtagatatg cttaacaaaa
     2401 tgtgttaagg aaaggagtta aggaatgaga atcgcaattg gatgtgacca cattgtcaca
     2461 gatgaaaaaa tggcagtatc agaattcttg aaatcaaaag gacatgaggt ccttgatttc
     2521 gggacatatg accacgcacg tactcactac cctatctatg gtaaaaaagt cggtgaagca
     2581 gtagtaagtg gtcaagcaga cttgggagta tgtatctgtg gtacaggtgt cggcattaac
     2641 aatgcagtca ataaagttcc aggtgttcgc tcagcgttgg ttcgtgatat gacatcagct
     2701 atatatgcaa aagaagagtt aaatgcgaat gttatcggtt tcggtggaaa gattactggt
     2761 ggtcttctta tgaatgacat cattgaagct ttcattgaag ctgagtacaa accaacagaa
     2821 gaaaataaaa aattgattgc aaaaatcgaa cacgttgaaa cacataatgc acatcaagca
     2881 gatgaagatt tctttacaga attccttgaa agatgggacc gtggtgacta ccacgattaa
     2941 ggtataacaa atgattctga cagtcacact aaatccttca gtagacatct cttatcctct
     3001 agaaacattg aaaattgata cagtgaatag ggtgaaagat gttagtaaga cagctggtgg
     3061 aaaaggctta aatgttacta gagtcttgta tgaatctggt gataaagtta ctgctacagg
     3121 tttcttaggt ggtaaaattg gtgaatttat tgaaagcgaa ttagaacaat ctcctgttag
     3181 tccagctttt tataaaatct caggaaacac tagaaactgt attgctatct tacacgaggg
     3241 taaccaaaca gaaattttgg aacaaggacc aacagtttct catgaagaag cagaaggttt
     3301 tcttgaccac tatagcaatc ttattaaaca atcagaagtt gtgacaattt caggaagttt
     3361 accttcagga cttcccaacg attattatga aaaacttatc caacttgctt cggatgaagg
     3421 agtagcagtc gttttggatt gttcaggtgc acctcttgaa acagttctaa aatcgtcggc
     3481 taaacctact gccatcaaac ctaataatga ggaactttca cagttgcttg gaaaagaagt
     3541 aacaaaagat attgaagaac tcaaagacgt tcttaaagag tcacttttta gtggtatcga
     3601 atggatagtg gtctcattag gtcgaaacgg tgcctttgca aaacatggtg atgttttcta
     3661 taaggtagat attcctgata tcccagttgt taatccagtc ggatcagggg actcaacggt
     3721 agctggtatt gcatcagctt taaatagtaa aaaaagtgac gctgacttat taaaacatgc
     3781 gatgacattg ggtatgttaa atgctcaaga aacaatgaca gggcatgtga atatgactaa
     3841 ttacgaaaca ctaaactcac aaattggagt aaaagaggta taaaaatggt acttacagaa
     3901 cagaaacgca aatctttgga aaaaatttca gataaaaacg gtgttatctc agctttggca
     3961 tttgaccaac gtggtgcttt gaaacgtttg atggcacagt atcaagatac agaaccaact
     4021 gtagctcaaa tggaagaact aaaggttttg gttgctgatg aacttacaaa atacgcttct
     4081 tcaatgttgc ttgaccctga atatggactt ccagcaacaa aagcattgga taaagaagca
     4141 ggtcttcttc ttgcctatga aaaaacaggt tatgatacat caagtacaaa acgtttgcct
     4201 gactgcttgg atgtttggtc tgcaaaacgt atcaaagagc aaggcgctga tgccgttaag
     4261 ttcttgcttt actatgatgt agacagctca gatgaactta accaacaaaa acaagcttat
     4321 attgaacgtg ttggttctga atgtgtcgct gaagatattc ctttcttctt ggaaatcctt
     4381 gcttatgatg aagaaatctc agatgcaggt tctgttgaat atgcaaaagt gaaacctcgc
     4441 aaagtcattg aagcgatgaa agttttctct gatccacgct ttaacattga tgttcttaaa
     4501 gtagaagtac cagttaacgt taaatatgtc gaaggttttg ctgatggtga agtggtttac
     4561 agtaaagctg aagctgctga cttctttaaa gcacaagaag aagcgactaa ccttccatac
     4621 atctacctaa gtgcaggtgt atctgctaaa ttgttccaag aaacattgca atttgctcac
     4681 gactcaggtg ccaagtttaa tggtgtgctt tgtggacgtg ctacttgggc aggatctgta
     4741 gaaccttaca tcaaagaagg tgaaaaagca gcacgtgaat ggttgcgtac tactggattc
     4801 gaaaatattg atgaacttaa caaagttctt gttaaaacag ctagtccatg gactgataaa
     4861 gtatagtaaa aacataaaac ggaggatatt gttatgaaca gagaagagat gactctctta
     4921 gggtttgaaa ttgttgctta tgctggagat gctcgctcta aacttttaga agcgcttaaa
     4981 gcggctgaaa atggtgattt cgctaaggca gatagtcttg tagtagaagc aggaagctgt
     5041 attgcagagg ctcacaattc tcagacagct atgttggctc gagaagcttc tggggaggaa
     5101 cttccataca gcgttaccat gatgcatggt caggaccact taatgactac tgtcttatta
     5161 aaagatgtga ttcatcacct catcgaactt tataaaagag gagcaaaata atgcataaac
     5221 tcattgaact tattgagaaa gggaaaccgt tctttgagaa aatctctcga aacatctatc
     5281 ttcgtgctat tcgtgatgga tttatcgctg gtatgccagt catccttttc tcatctatct
     5341 ttatccttat tgcctatgtc ccaaatgctt ggggattcca ctggtcaaaa gacattgaga
     5401 ccttcttgat gactccttat agctattcga tgggtatcct agcattcttt gttggtggta
     5461 ctaccgctaa agctttgacg gactcaatga accgtgacct acctgcgacc aatcagatta
     5521 acttcttatc tacgatgcta gcgtctatgg tagggttcct tttgatggca gctgagcctg
     5581 caaaagaagg aggcttcttg acagccttca cgggaacaaa aggtcttttg acagcattta
     5641 ttgcagcctt tgtgacagtt aatgtttaca aggtctgtgt gaaaaataat gttactattc
     5701 gtatgcctga agaggttcca ccaaatatct ctcaagtatt taaagacttg attccattca
     5761 ctgtagcggt tgttctcctt tatggatttg aactcattgt taagggaact cttggtgtaa
     5821 ccgttgcaga atcaatcggt accgttcttg ctcctctctt ctcagctgca gatggttacc
     5881 ttggaattac acttatcttt ggtgcttatg ccttcttctg gtttgttggt atccacggtc
     5941 cttcaattgt cgaaccagca atcgctgcta tcacttatgc caatatcgat gccaacttgc
     6001 atcttatcca agctggacaa catgcagata aagttatcac ttctggtact caaatgttta
     6061 ttgttaccat gggtggaaca ggagctacat tgattgttcc attcttgttc atgtggattt
     6121 gtaaatcaga acgtaaccgt gccatcggac gtgcctcagt tgttccaaca ttctttgggg
     6181 ttaatgagcc aatcttattt ggtgcaccaa tcgtattgaa tccgattttc tttgtaccgt
     6241 tcattttcgc tccgattgtc aacgtttgga tctttaaatt ctttgttgac acattgaaca
     6301 tgaactcatt ctctgccaac cttccatggg ttactcctgg tccgttggga attgtactcg
     6361 gtactaactt ccaagttcta tcatttatct tagccggact cttggtagtt gttgatacta
     6421 tcatttatta cccatttgtt aaggtatacg atgaacaaat tcttgaagaa gaacgttctg
     6481 gtaaaacaaa cgatgctctt aaagaaaaag tagctgcaaa cttcaatact gctaaagcag
     6541 atgccgttct tggaaaagca ggcgttgcta aagaagatgt agcagcaaac aataatatca
     6601 caaaagaaac taatgtcctt gttctttgtg caggtggagg tacaagtggc ttgcttgcca
     6661 atgccttgaa caaagcagca gcagaataca atgttccagt caaagcggca gcgggtagtt
     6721 acggtgctca ccgtgaaatg ttgccagagt ttgacttggt tatcttggct ccacaggtcg
     6781 cttcaaactt cgatgatatg aaggctgaaa cggataaatt gggcattaaa cttgcaaaaa
     6841 ctgaaggagc tcaatatatc aaattgacac gtgatggaca aggtgctctt gcatttgttc
     6901 aacaacagtt tgattaataa atttgtaaaa gttatttgag acgagattat tctttcagtt
     6961 ccttataata ttgttaacca tatcattgca tttcatttcc ttggtttccg gaactcagaa
     7021 tatcgtctca aatgcttttt ttgaaaggat ttatagttat gactaaaaca cttcctaaag
     7081 attttatttt tggtggtgct acagctgctt atcaagcaga aggtgcgact cacacggatg
     7141 gtaaaggccc agttgcatgg gataagtatc ttgaagacaa ttattggtac acagcagagc
     7201 ctgcaagtga tttttaccat aaatatcctg ttgatttaga attagctgaa aaatatggcg
     7261 ttaatggtat tcgtatttca attgcctggt ctcgtatttt cccaactggc tatggcgaag
     7321 taaatgaaaa aggtgttgaa ttctaccata atctttttgc cgagtgccac aaacgtcatg
     7381 ttgagccatt cgtgactttg caccactttg acacaccaga agttcttcac tcagatggag
     7441 atttcttaaa ccgcgaaaat atagaacact ttgtagatta tgccgctttc tgttttgaag
     7501 agttcccaga agtaaactac tggacaactt tcaatgaaat tggcccaatt ggagatggtc
     7561 aatacttggt tggtaaattc cctccaggca ttcaatatga tcttgccaaa gtcttccaat
     7621 cacaccacaa tatgatggtt tctcatgcac gtgctgtgaa attgtataaa gataaaggtt
     7681 ataaaggcga aattggtgta gtacatgcgt tgccaaccaa atacccttat gatccagaaa
     7741 atccagcaga tgttcgtgcc gctgagttag aagatatcat ccataacaaa tttatcttgg
     7801 atgcaaccta ccttggacac tattcagata aaacgatgga aggggtcaac cacatcctag
     7861 ctgaaaatgg tggagaactt gatcttcgtg atgaagactt ccaagcactt gaagcagcta
     7921 aagatttgaa cgatttcctt ggtatcaact actacatgag tgattggatg caagcctttg
     7981 atggtgagac tgaaatcatt cacaatggta agggtgaaaa aggaagttct aagtaccaga
     8041 ttaaaggtgt tggtcgccga atcgcaccag attatgtgcc tagaacggat tgggactgga
     8101 ttatttatcc tgaaggcttg tatgaccaaa tcatgcgagt gaaaaatgat tatccaaact
     8161 acaagaagat ttacatcact gaaaacggtc ttggatacaa agatgagttt gtagataata
     8221 ccgtttatga tgatggtcgt attgattacg tgaagaaaca cttggaagtt ttatcagacg
     8281 caattgcgga tggtgcaaat gttaaaggtt acttcatctg gtcacttatg gatgtcttct
     8341 catggtcaaa cggatacgaa aaacgttatg gactattcta tgtagacttt gacacgcaag
     8401 aacgctatcc taagaaatca gctcattggt ataagaaagt agcagaaact caagtgatag
     8461 agtaatatta cttgaaaatg taaaaaattg ttatccgata ctttagaaaa agtacaacac
     8521 ttatttagac caggctttga aaaggtatat attgttagtt tcgaagattg tcctatgatt
     8581 cctgagcttg aagctacccc gttgctaaaa tgtggtaaat ggtatgtttc aactggaaaa
     8641 gagtggattt gccattctga tttagagtta tcagcatttg aatgggaatt tttacaatca
     8701 ctcgatgtag aaatacgtga gactattcac ttcgaggtaa attatttgcc tttccaataa
     8761 taaaaagaaa ggaattagtt gtgactatcg aattaaaaaa cgagtatctt actgttcagt
     8821 ttaaaacact tggtggtcaa ctgacttcga ttaaagacaa ggatgggata gagtatctct
     8881 ggcaagctga tccaaattat tggaatggac aggcgcctat tctatttcct atctgtggta
     8941 gtttacgaaa tgattgggct atttatagac ctcaagaaag accttttttt acaggtctta
     9001 ttcgtagaca tggttttgtt cgaaaagaag aatttattct ggaagaagtc aatgataata
     9061 gcgtgacctt tagtattaaa ccaaatgctg agatgcttga taattaccta tatcagtttg
     9121 aactgagagt tgtttatacc ttgaatggta aatcaattag aaccgaattt caggtaacga
     9181 acttggaaat ggaaaaaaca atgccttact ttattggagc ccatccagca ttcaatagtc
     9241 ctttagtaga aggtgaaaac tatgaggatt attatattga atttagtgag gttgagtctt
     9301 gctcgatacc aaagagtttt cctgagacag gattattaga tttgcaagat cggacacctt
     9361 ttttggaaaa tcaaaaaatt ctcgatttgg actactcact tttttcccat gatgccatta
     9421 cacttgacca gctcaagtct cgtagcgtaa cgcttcggtc aaggaagtct ggtaaaggtc
     9481 ttcgagtaga ttttgatgat tttccgaact tgattctgtg gtctacaact aataaaagtc
     9541 cattcattgc tttggaacct tggagtggtc tctccacttc acttgaagaa ggtaatttct
     9601 tagaagataa aagacaggta acgaaaattt cacctcaaga aacttctaga aaaatctatg
     9661 atattactat ccttaattaa aatttgttat tatttgagtc ttcaataaga tttgaatact
     9721 cttaccttgt gatgatagat tggtcttctc cgtgccagtc ttacatcgca aggtttttaa
     9781 gttttttgtg ggtctatgtc aactgtagtg ggtgacgaaa agctaatatc taaagacagt
     9841 ctggtagtaa aaaataagat tatttactac ttcttgattt aaaataatag tggagccatt
     9901 aatttgtggc aaatttaatt taatattttg cctcaaatta gccacacttt ttatagaact
     9961 aagaggaaaa atgaaatttt cttcctatta atatagttgt ttgaaatctt aaatatagcg
    10021 t
//
LOCUS       DAFELK010000079         9835 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFELK010000079
VERSION     DAFELK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.082"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            513..1076
                     /locus_tag="LP433_002578"
     CDS             513..1076
                     /locus_tag="LP433_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006698.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1137..1502)
                     /locus_tag="LP433_002579"
     CDS             complement(1137..1502)
                     /locus_tag="LP433_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006699.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1578..1823)
                     /locus_tag="LP433_002580"
     CDS             complement(1578..1823)
                     /locus_tag="LP433_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006700.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1893..2147)
                     /locus_tag="LP433_002581"
     CDS             complement(1893..2147)
                     /locus_tag="LP433_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006701.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2311..2634)
                     /locus_tag="LP433_002582"
     CDS             complement(2311..2634)
                     /locus_tag="LP433_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006702.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2821..2894
                     /locus_tag="LP433_002583"
     tRNA            2821..2894
                     /locus_tag="LP433_002583"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2855..2857,aa:Ile,seq:cat)
     gene            complement(3279..3776)
                     /locus_tag="LP433_002584"
     CDS             complement(3279..3776)
                     /locus_tag="LP433_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2006703.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3816..4625)
                     /locus_tag="LP433_002585"
     CDS             complement(3816..4625)
                     /locus_tag="LP433_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2006704.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4959..5816
                     /locus_tag="LP433_002586"
     CDS             4959..5816
                     /locus_tag="LP433_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL2006705.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5809..6711
                     /locus_tag="LP433_002587"
     CDS             5809..6711
                     /locus_tag="LP433_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL2006706.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6744..7094
                     /locus_tag="LP433_002588"
     CDS             6744..7094
                     /locus_tag="LP433_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL2006707.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7143..8066
                     /locus_tag="LP433_002589"
     CDS             7143..8066
                     /locus_tag="LP433_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL2006708.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8144..9037
                     /locus_tag="LP433_002590"
     CDS             8144..9037
                     /locus_tag="LP433_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2006709.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9075..9638
                     /gene="amaP"
                     /locus_tag="LP433_002591"
     CDS             9075..9638
                     /gene="amaP"
                     /locus_tag="LP433_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL2006710.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9652..>9835
                     /locus_tag="LP433_002592"
     CDS             9652..>9835
                     /locus_tag="LP433_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL2006711.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFK"
BASE COUNT         3423 a         1663 c         1849 g         2900 t
ORIGIN      
        1 aaaattcatt ggtcgttgaa tgggctgaat agtagtgtat aaaacaattt tgtggagcgt
       61 gaagctttta tggtagagga aaatacgaat aaagtgatgt tgataaaaag attcctatct
      121 tgaatatgaa tcgagatgtc ttgaaaatga atgagtttga ccaatcatta tcctatcgaa
      181 atttacagtt tcgttcgatt ggtctgtcaa ttaatgaaaa agtaaaaaag aatatgttct
      241 aggaagaggg cggcacatct aaatttttaa gtaacggaca gttcaaatat caagcattga
      301 aagaggctat cctactgttt gaaggaatac gaatatataa aaacgacaaa gaggaaaaag
      361 tagttcatta aatcccttca agtgatgaaa gaatgagatc taataaaacc tgatctttca
      421 tctgtttttt taataacgta ataatttttt tattttttgt gctttcgccg ttattgtaga
      481 gtgatttagc attcttattt ttaaaaataa ctgtgttata tattaaaaaa ggcataatag
      541 ttataagctt ttttaaagaa tatttagaaa ttattaattt tcgtctgaaa acaaaaaaag
      601 aaagcgttat tattttagtc tattttcagg gggggaacct tatgataaaa aaactatttt
      661 tactatcaat attaacgcta gcaatggcag gttgttctga ctctggctta gcaactgaac
      721 tgatcacaaa atcaactgaa gccacgacag aggagttaaa atgtggaaac gatcacagtg
      781 actacagagg cttaaatcga cgatgcatgg gaatattagg cagaagcaat tgtaagcatc
      841 gatgtagtaa tcgaagaagg tgtagaagaa gcaacagaaa aatcaaaaga aagatcaaaa
      901 gaagcaatct gtgctgtgca tcgtatacag acgtcgaaga tgcggtactt ttaaaccacg
      961 tcaggagatg ttcatttatg tctagggaag ttggcgatga accaaaacta gagtacgctt
     1021 ttagttttgc acgtgaggat gaagataacc ctaaaactta cgacatttta gcttgatcta
     1081 agatggttaa agctttttaa tgaagtaaga ggagatagaa ggcttttcta gttatattag
     1141 gtaagataaa ttcctttttg ctccaaattt gctaaacatt ctgctagata aacttcatcg
     1201 tgttccggat aaatcggcac gttgcgctct acagtaggta aatcaaaaaa tgcttcgcat
     1261 gatttgccac gatacatagg atttttccac tctggtgctg ggctgtaacc acgtttttcc
     1321 atttcatcca tgacaagctg atgatattgg aataatctat aaggagaata gtgaaaaaca
     1381 taatccacag tagcatgttt ctttccccag ccatttcctc ttaatgcaca gcattcccga
     1441 tgttgtccta aaagctgttg acgaggaagc tttgaaatca atttttcatg ccataatcgc
     1501 atagaaatgt ctcctttata tatagattgt taaccttaga cgttaaatga aaaaaccagc
     1561 accaaggctg gaaaaaatca cttcagtttg cttgctgttt ctgagcgacc aattaggtaa
     1621 tcaacggaaa tatcgtaaaa gtcagcgata tagattaatt caatgatgct tggaatttct
     1681 tctccttctt cgtacttacg atatttgaat aaaggaatac ttaacgcgct agaaacagct
     1741 acttgagata aagatcggcc agttcttaag aaattcagac gacaacgtaa agtatccagt
     1801 aaaatagctt cttcgatact catttaatca cctttcatta tagtagaata gttataatga
     1861 ctatagaaag ctacacatgc aatcaatagt actcaatgtt ttttatttaa acgtatcaaa
     1921 taaagaatga cgatcaataa agacaaaacc agtcctgata attcttctat aaaaacacta
     1981 tcgggttcaa agtagttgta attaaaaact ttccacataa agtagatagc cggaagagtc
     2041 aaaatagcta aataaaaccg ttctttgttc caattcataa gataaacaat acttgcgacc
     2101 agtgcgaccg caggcaccca aaacaaaact ctcaccaacg taatcatgta acggactcct
     2161 caacgattca tataataaaa gataacatgt tattgcatac atcacaaatg aaatgctagg
     2221 aaaataaaag aagaatagat caatgaaaaa tgaaaaagca gaacagtttt ctgctgataa
     2281 gcaggaactg ttccgctgaa tgtgtcttat ctatcgagaa aaaatcaatg gattgatatc
     2341 taagtaattc aatacatata aaaagaggac gatcgcattc actaaaaagg aaagaatgat
     2401 gatcccatag cgaatggaaa catatttaac aaatactttt gtttgaatac gggcatatct
     2461 ttttccttta tagctgagca tcatgacaag aagcaaaagg gtaatcacac cttgaaaaat
     2521 cattccaata aacagaattc ctgaggtttg ataatttaat tggagaaaat aagctgctgc
     2581 cgcaactaaa tcgaataaaa tcgcaataaa tggcaaaata atcactccta acattgagaa
     2641 taaataaaag aataacattt tttctaaaat aagcaaataa aaattaaagt aacaaaatag
     2701 ttatgacaca agtaaaagaa ataagaataa caatattatt ttacttatat tttgaaactt
     2761 gtgagagttt gtcattcgtg ctatagttga aaagtaacaa aaataaattt tatttatgat
     2821 gtacctttag ctcagttggt tagagcagac ggctcataac cgtccggtcg taggttcgag
     2881 tcctacaagg tacataagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
     2941 caagtaaaaa cagcttctta tgtttttact tggctgttct tattactgca gatgcaagct
     3001 tttgaatacc gtttaaggaa gaggttgtga aatcagcgtt ttgacctgag tattagctta
     3061 acaaacggaa aaatagttcc tcatattttg ccgtttgtta agctaatacc gagggtcagc
     3121 tgattgaaca ccatttaaga aagaggtcgt gagcctgccg tttcactctg tgtcataaaa
     3181 aagccaatct actttgatag aaaaagcacg taggactaaa acagttctgc gtgctttttt
     3241 tattgtgtgt taaatatcgt aaatgaagat agatattttt atgattcgac gatagagacg
     3301 ttgaaatctt tcaacagctc taaagcggat tctccgtgtt ttctactgga gactaacatt
     3361 ggatcaacaa aaaagtctgc ttcaggaaaa gcactctgca ggcctatcag attagagagt
     3421 acacacaagt ttgtttcaat cccgactact tcgatctctt tttgttcttc tttgctttca
     3481 aataaagttt cctggatttc agctaaagtt tcaggtggaa tcgtaaagta atacttttta
     3541 atcactcgtt cattttcttg tggagaaaga agagggatca attgcaaatc ttctcgttct
     3601 tcttctttgt ccttcagttc aactggtata tcccgtgtga agagaatata ttcattattt
     3661 tggcgtgctt tagctaatct ttgagcaata cgttctgcca attgatctga ctctggaata
     3721 taaaattcgc tgtttggatc aagaatatga ttttgcatat caataataac taacattttc
     3781 tttcctccta cattcatatc gtcattttat tctttttaat agaagttttt taaaatataa
     3841 gcaacaccag cttcttcatt cgtcagtgtt acttggtttg caatttcttt tacttgtcgc
     3901 tgtgcattcc ccatcgcaat actcaacccg ctgtaattca acatagcaat gtcgttttct
     3961 tgatcgccaa aagccatgat gtcactcgat tcgattccaa ggtaatccgc cagaaaaaca
     4021 agtgaatgag ctttagtgat acctgtaggc gtgatttcta agaaatgcgg atcagagaat
     4081 actgattgga taccatctgc ttgcagatct ctttgtagct tctgtagttt ttcttcactc
     4141 ttatctgtta atgctaattt aagatagcta agagaaggat cttccaacat atttaaaatt
     4201 tgatcaaaag aatggttctg taaattgaaa tgttcataat aagggtcatc tttgactaga
     4261 tttgattcat cgaatgtcag ctgatcatct tgggtttctc ggctagcaat gatggatatt
     4321 ttcgcttctt gagcatagaa gaaggctttt ctcagtgtat cgctatctat ttttgaacgt
     4381 ctgagaactt tcgccatttt tccatccttc atttcagcaa tcagtgaacc attggaagaa
     4441 atcaaatagc caccgattcc taattcggaa aaaatatctt tagcagaaat gctgttcctt
     4501 ccggtagcga cggttacgat tccgccattt tcatcaaatt tccgaagtgc ttggatattt
     4561 tcttctggta tctttccatt tcgatcaagc aaggtaccgt ctaaatcaat cgctgctagt
     4621 ttcattttat cttcctactt tctttttaca tatctatttt cctgttacct taagattaaa
     4681 tgagaattta aaaaaatgaa actaacttgc tttgtcatta tgaatttttt caaaaaacat
     4741 tcttaagaaa aaggtggcta tatatagtag tttttggtca atacctttga ataaaaagcc
     4801 atgaaaaacg aatagttagc gcttaccgat gcgttttgtg ataaaaaaat tttaaaatat
     4861 tcaatgaaaa caaagcatat attttgcttt aaaaccaaat gaggaatatt ctagatgtag
     4921 aacaggttag aaaaagatta gaaaaaggag tgattttgat ggagaagaga tacggcgtag
     4981 ttcctgtggt aactgcttca gacgaaaatt atgctcctta cttgagcgtg atgatcgcaa
     5041 ctgcattaga aaattgcaat aaaacaagac gcataaaatt ttatgtgatt gacgatggtc
     5101 tatcagaata tagtaaagaa ggattggaag aaacggtaaa taaatattca agtaatgcaa
     5161 gtatccaatt cctgacagtg gaaaaagata tctacgaaga cttcctagtc agtgaccata
     5221 tcacaactac cgcttactta agaatttctt taccaaactt attagctaaa gaggattata
     5281 agaaagtcct ttacttagat tcagatgtgt tagtactaga cgatatcgta aaactatatg
     5341 atgagccgtt aaatggaaaa acaatcggcg ctattatcga tccaggccaa gtgaaagctt
     5401 tggaaagatt aggaatcgat tccgatgact tgtacttcaa ttcaggagtg atggtgattg
     5461 acattgatca atggaataaa aaagaaatta cagaaaaaac tatccattac ctcagtgaaa
     5521 atggcgatcg aatcatctat cacgaccaag atgctttgaa tgctgtactt tatgaagatt
     5581 gggaacaact tcatccaaaa tggaacatgc agacttcgct gatttttgaa cgtcatccag
     5641 caccaaatga aaaatatgaa cgtcagtata aagaaggaaa tgaaaaacct tcgatcgttc
     5701 actttacagg acatgataaa ccttggaata cgttgaaaga tcatccgtat accaatttat
     5761 acttaaaaaa attagcacac agtactctaa cgaaagtagg cgagatcaat gaataaaaaa
     5821 gaaatagcag tagtcgcaag ttgtaacaca aaattcgtac cacatttagc tgcattattt
     5881 gtctcagtat tagataattg caacccgtct aaatttgttc ggttctatgt gattgacgat
     5941 gatatcgatt ttgaaagtaa acagctttta cgcttctcag tgaaaaacgc acgaatgaac
     6001 tcagatgtgg aattcttgaa aatcaataaa gaattcttta caaatgtggt aatcagcgat
     6061 cgtattccag aaacagctta ttatcgtatt gcgattccgg aattgttccg cggcacagaa
     6121 gttgaacgta tcttatatat ggattgcgac atgatcgctt tacaagatat ctctaaatta
     6181 tggcgtcttg acttcggtga ttcaatcgta gcagctgttg aagacgctgg gttccatcaa
     6241 cgactggaaa aaatgaaaat ttcagctaaa tcaatgcgtt atttcaactc aggtttgatg
     6301 ctgatcaatg tgaaaaaatg gttagatgaa aatattacgc aaaaagtatt agatttcatc
     6361 gaacataatc cagaaaaatt acgattccat gaccaagatg cattaaatgc tatcttacat
     6421 gaccgttggt taccacttca tccgcgttgg aatgcacaag gctatatcat ggcaaaagca
     6481 aaaaaacatc caacagcagc aggtgaacgt gaatacgaag aaactcgcaa caatccttac
     6541 attatccatt tttcaggaca tgtgaaaccg tggagcaagg attttgaagg gccaacgaag
     6601 aaatattacg aaaaatatgc agggatgacg gctttccgtt gtgtagctaa attccctaaa
     6661 tatccaaaat atgcaaaagt tcaaccaaaa acagatgtag ttgttaaata atagaagaca
     6721 acaactgaag agggggagta ggaatggaaa ttacaatgtc taaaaatgca gtagagacgt
     6781 taattgaaaa ggttggggaa aatacaaaaa tcgcactcgc gcttatcaat gattccgatc
     6841 catttctaag ggacaaaggt gcttttgcaa aaggcagctt ttttcaaatc attccttttg
     6901 tttcggaatt tggagaatat gcgactaaaa tcgagcatcc attattggac atctatacat
     6961 ctaaattaga gcaaaattat ttcggtaaac gattgaacat ggacttcaac aaacagcttg
     7021 acagcttttc attagaaaat gaaatcgcag tactcgatta taatatcaaa ttaaagaact
     7081 gcttcttcag ctaatagttt cgagaaagtc caaaaaggag gtatacattg agatactact
     7141 ttgtggatga agaaaagaat gtaatagaaa cagatgaaaa aaaatataat tggctcgtac
     7201 ttgatagtgc aaagcccgaa gagattgagc aagcaatcga agaattcgag cttcctgatg
     7261 atattttcgt aggaaccgaa tatccggaag aagtttctcg gatggagcgc ctttatgaga
     7321 cgaaactaga gcatccattt tctttggtag tgattaatct agatcagtca gataatcgta
     7381 tcgaaaaaaa attaacgcca atatcttttg tactttccga taatctcttg attacttgta
     7441 tcgatagaaa aaccgaattt gtggatcggc tgctgacaaa gcatggaaat catttaaact
     7501 cgtttgaaaa gatcatcacg tatacattat tagatattta cacccattac gtgaaagaac
     7561 taagagagat gaaaaagcga attgacgctt tggataaagc agctcgtaaa acaacggaaa
     7621 atgaagaact gtataaacag gcagatcttg aaagagacat cgtatatatc gatcatacct
     7681 taagagatca acgggaaaca atggatcaat tatggaattc tgaaactttc atcaaacgtt
     7741 tagacgatga acagctactc tatgatgtcc atttgagaca gcgacaaaca gaaaaaatga
     7801 tcgagatcta tcgagattta ttagagagta ttggtgatct attcaacggg atgatggaca
     7861 ataatctaaa tcatatcatg aaatatctag attcagctgc attaatcatt tccgttccgg
     7921 cgttgttcgc agggatttgg ggaatgaata caggaggatt accgggtaaa agttctgctc
     7981 taggctttat actcgtagtc tttggctctt tgatagcagc agtagtttta ggttaccatt
     8041 tataccggaa agattataca aattaaagaa tctatttaaa acaggtatca aacaaagaaa
     8101 tttgttttgg caatacaatt taaaaactag gaggaataca gcaatgacag aaccaaaatt
     8161 aatcgacccg cgaaacttgt accatacgga gaaatttcct aaacaagatc aggatacacc
     8221 agctttacag cagaatatga ttcctgttcc tgattgtgga gaagaatcct atgaaggcaa
     8281 taatcaacta gaaaaccgcc gtgtactaat cactggtgga gattcaggga tcggtcgtgc
     8341 agcagcgatt gcatttgcta gagaaggggc agatatcgct cttcaattct tcccaggaga
     8401 agaaaaagat gcagaggaag tagcaaaata cgtgaaagtt gcaggacgta agattgtctt
     8461 actacctttt gatcttcgtg acgaacaagc acctaaagaa atcatagata aagccgtgag
     8521 tgaacttggc gggctagata cgatggtact aaacgcagga cagcaaattt cttgtcagtc
     8581 tattgctgag ttaccacttg agcaagtcaa agacacattt atgataaaca tcatcgctat
     8641 gtttgcttta gtgaaagaag ctgttccgca tatcccagca ggaggagcaa tcgtaacaac
     8701 aacttctgtt caagcattca atccaagcga acatttatta gattacgcag caacaaaagc
     8761 ttcaatcgct aactttacga tcggtttagc aaaacagctt gcacctaaag gaatccgtgt
     8821 aaatggtgta gcacctggtc caatctggac accattacaa ctagacgaag gacaaccttc
     8881 tgattcgatc cctgaatttg gtcagcaaag tttactagaa cgtgcaggtc agccaggaga
     8941 attagcacca gtttatgttt tcttagcatc gaataaagca agttatgtta cagcccaaat
     9001 ttacggagta actggtggag aagcgatcaa cttataagaa gttgatcgtt tcacccctat
     9061 gaggaggtgc gaaaatgaat aaaggtgtaa aaacgatcgg agtgatcgga acattacttt
     9121 tgctatctgt gcttttgttt gcgatactat taagtgcaac ctatccattg ccttttcagc
     9181 tagagaagtt tcgattcttt tccatcacta attcatacgt gcaacaatat gtattttggc
     9241 ttgccgttgc atttgctatt ttgacaatta tcacgttact tgttttcctg ttttatccaa
     9301 aaacaatcgg aaactttcta ctgaaacatg gtgatgggga gttgacgttg gataaaaaag
     9361 caattgaagg aatggttcgt tctcacttgc atgaagatga attcatccat tcaccaaaag
     9421 taaatgtcaa agcaacgaaa aacaagatcg ccgtcaatgt aaaaggggag ttgaaacgaa
     9481 cttcagcact cattggtaaa acaggaacat tgatgaaaga aatcgaaaat gaagtacaac
     9541 acatattggg aacaaaagag ccagtgaaag tatcggtgaa atacacaggc tttgaagaac
     9601 cagctaaacg aagcaatgac cgcaaacgag tagaataggg ggggaccaaa aatgaaagaa
     9661 ctattttcga catacaagct ccctatcatc tttggggtac ttggattgat attagccgtt
     9721 ttatggatca ccgtgggctt tttcaagacc ttattgatct tgatcatggc agcgatcggc
     9781 gtcgctatcg gtttttatct gaaacaaacg aaaatcttag atcactattt taaat
//
LOCUS       DAFELK010000080         9265 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFELK010000080
VERSION     DAFELK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.084"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            51..260
                     /locus_tag="LP433_002593"
     CDS             51..260
                     /locus_tag="LP433_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006712.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..667
                     /locus_tag="LP433_002594"
                     /pseudo
     CDS             467..667
                     /locus_tag="LP433_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1379..1984)
                     /locus_tag="LP433_002595"
     CDS             complement(1379..1984)
                     /locus_tag="LP433_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006713.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2166..2501
                     /locus_tag="LP433_002596"
                     /pseudo
     CDS             2166..2501
                     /locus_tag="LP433_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2666..2893
                     /locus_tag="LP433_002597"
                     /pseudo
     CDS             2666..2893
                     /locus_tag="LP433_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3019..3990
                     /locus_tag="LP433_002598"
     CDS             3019..3990
                     /locus_tag="LP433_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2006714.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4130..5443
                     /locus_tag="LP433_002599"
     CDS             4130..5443
                     /locus_tag="LP433_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBL2006715.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5486..6352
                     /locus_tag="LP433_002600"
     CDS             5486..6352
                     /locus_tag="LP433_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2006716.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6349..7197
                     /locus_tag="LP433_002601"
     CDS             6349..7197
                     /locus_tag="LP433_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2006717.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7211..8683
                     /locus_tag="LP433_002602"
     CDS             7211..8683
                     /locus_tag="LP433_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBL2006718.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8700..>9265
                     /locus_tag="LP433_002603"
     CDS             8700..>9265
                     /locus_tag="LP433_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2006719.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIE"
BASE COUNT         2909 a         1583 c         1921 g         2852 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgaaac atttgaagtg atcctagata aaattaaaca
      661 gaattgatca gaaacaagcg aagccttctc tcggttcgct tgttttgcta tttattagtt
      721 ggctcagggc aactctaagc tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta
      781 ccactttaga atacatggat gtacgtattg ccattgactc ctattagtta ctgaaaaaaa
      841 atttaaacaa gttgagtatt gcagataaat agctccagtg aggtgaataa ctgctccact
      901 caaggcaata gatagctcca tccagggcaa caaactgctc cactttcata tttaatagat
      961 gaataacctt ctgtataata gaaaggcata cctttcggta tgacaactta tacagaatgt
     1021 tattttattg gttcactatc gaaaaatttt ggagctttat ttttccggta tttctcaacg
     1081 aacgattagt ttaactgtgg gaagctccag acatacgatt cgagaagtta cttctcgagc
     1141 agacaggaag ggggtgactg aactaaccgc tgatatgagc gatacttggc tgtaggaata
     1201 tctttttccg gaaaaacaaa caacagcacg aggttacctt cctgtagact gggaatatgt
     1261 tcataaagaa ctaatgaaaa agaatatgac attgaaactc cttcatagag aatatggggt
     1321 acatggaaca tagaaacgaa aatgcacggt agaaaagcga atgaatatag tataaattct
     1381 acaaatcatt cgctttcttt attttatata tggttggtcg agagagacca ttttctttgg
     1441 caatttctgc aactggaact ccttgattta acatgtccac cacagtttta aagactaatc
     1501 gtttttgcgg atctgttgag ttctcagaat attcaattgg tcgcccctta tatcgaccag
     1561 cttttttggc caataatact ccttgccgct gacgttcacg gattttctca cgttcgtttt
     1621 gtgcaatata acttagcaat gataaaaaca tatcgaacat agcagtatct aggagttcat
     1681 ttccagtatt aaaatctaaa aactgtgcat ctagtatttt taatgctact tttttctgtt
     1741 tcataaaggt aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg
     1801 caacaatgac acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcgct
     1861 ggatatcttt accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca
     1921 ttgccaattg tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg
     1981 ccataaaaac tccttttaaa aaatgatata atttacatgt aaaatttact tgtagtttta
     2041 ctgttatcat agcattttta aaaataaatt ttaagtctac ttataattta ctttggaggt
     2101 tttgaatgaa tgaaattaag cgcaataaaa attcttttgg tgtttattta ggagagccta
     2161 gctcggaaca gttaaataaa ggtgaagctc gtcatgctct atgtcgaaat atattttatg
     2221 gtagaaaagg caaactttat caaacttatt acgacggtat ggaggaacag ctcaacgcat
     2281 taggattagt aactaatgct atcatatatt ggaattcact atatttagaa aaagtctttg
     2341 aacaaattaa aacggaaggg ttcgactgtt ccgaagaagt gttacgcaag caatttccat
     2401 taattagtga tcacattaat tttgttggca aatatagttt ccgctatgaa aaagaattat
     2461 cgaatggaat actacgtccg ttaaatatag agaattattg agaatgttcg tcttttggtt
     2521 cctaccgtgc attttcgcac ggatgttcca gatactattt ttgaatgtat aaaattgaaa
     2581 acacaagaat actaataaat caacgattct tgtgttttta atttttcact accgtgcatt
     2641 ttcgtttcta tgttccatgt accccaatct tgaaaaatta attaaagact tagataaagc
     2701 cattgacgac ttagtcgtgg tgctaccgga gtatcaatgt ttaaccagta tcccaggtat
     2761 tggtcctgtt taggctgctg gaatactcgc tgaaattggt ccaattgaac gtttttctga
     2821 tgaaataaaa ttgacaaagt atgccggcct atattggcga cagagtcaat ccggtaaatc
     2881 tgaatacgaa aattttttta cgaaaagctt cacgtctaat atctatttta aaataaaaat
     2941 attcctgcta atttggaatc gtttccttct tttggtataa taatacctga aattcttttg
     3001 agaggagttg ttcgtgaagt gaaaactact atgaaggatg ttgctgcgtt agcaggagtt
     3061 ggtgtgggta cggtatctag agtaataaat ggagtaaagg tgaaagaggt taccaaagaa
     3121 aaagtaatgg ctgcaattag tgagcttaat tatgagcctg atgaatatgc cagaggtatg
     3181 aaaacgaata gtagcaatac aatagctctt attttaccta cgatttggca tcccttcttt
     3241 tccgagtttg cctactatgt agaggaagct ctcagccaaa aaaattataa gctttttttg
     3301 tgtaatgcga acggcagtgc ggaaaaagaa aaagaatata tccaaatggt caagcagagt
     3361 aaagtagacg gaattatagg tattacctat tcagacattg ataaatatgt atcatcaaat
     3421 ttaccatttg tcagtataga ccgccatttt tcggaacagg tttcttatgt aacggcagat
     3481 aattatttag gtgggcaaat tgccgctcaa gaactactta ctcgtaactg taaaaacttg
     3541 tgctatgttg ggggtgtttc accttaccct aacgaaacaa acaatcgtaa agctggtttt
     3601 tacaatattt gtgaggaaaa taaaatagct gtgaaggtat tggatatgcc tgaaccaatt
     3661 agcaatttag aggaacaatt gctcgctttt ttttcggata atcctgaaat tgatagcatt
     3721 tttaccatca atgatttcat ggctttggat gtgataaaag cccaaaaaaa actagggaag
     3781 gaagcaccta aggattttca aattattggt tttgatggag tcaagctatc gttgcaaaaa
     3841 gactatttac tatcaacgat tgtacagccg atagaggaaa tggccaaggt ttcagtagaa
     3901 acactcatgg cgatgatttt aaatgaagaa ccgcctaagc gtgtggtagt accggttttc
     3961 tttcacgctg gagagacgac taaagagtaa aaaaccggtt tataacgatt tttttgagat
     4021 aggttgacag aaagtgattt caatgatatc ttaaaaccaa ttaattggaa acgttaccaa
     4081 ttaattgaaa aataaaacgg aaacgtttca aaaaatagga ggaacatcga tgaaaaagag
     4141 aatgttagca attgcagcaa ttttagcatt aacagctgga ggacttgcag gatgtggcag
     4201 taaggagaaa agttcaggta gcagtgatcc aggagaaatt aagatttggg ttcagttttc
     4261 tgatgaaacg cctgaaggaa aagcttgggc agagattgtg aacaatttta atgatgaata
     4321 cgagggtgaa tataaagctg ttactgagta tattcctcgt agcggaagcg gcggtggata
     4381 tgaggataaa gtaaatgctg caattacaac caataccctt cctgatgtta ttacgttaga
     4441 tggaccgaat actgcagctt atgctcattc aggagtcatt gctccattag atgattattt
     4501 gaaagatgcg gacatggatg atgtattaga cagcattatt cagcaaggaa cctacgatgg
     4561 caaaatgtat gcgtttggtt tctcagagtc cagtgtgggt gtctattaca ataagtcgct
     4621 gttcaaagat gctggaatta cagaagatca attgccgacg ttagaagatc cttggacttg
     4681 gacggaattt caagcaattt gccaaaagct gactgataaa tacaaaacgc ctgcaattga
     4741 tatgcaaatg gcgtcgggag acgaaatgct gacctacgca tatacaccat ttatatggtc
     4801 gaatggcggc gatgtcgtta atgctgatgg aaccaaagcc gaagactatt ttaacggtaa
     4861 aaaatccgtt gaagcgttgg aatttattca agaattggtt gaaaaaggtt acaccacaat
     4921 cagtcctatt gaaaaaggat ttgaaactgg caaatatgcc atgatgctga gcggttcttg
     4981 gacaatggca gatttagagg aaaactatca agagattgat tatggtattt tgccttaccc
     5041 cgtttcagat gcaactgggg agttagtttc accaaccgga agctggcagt tagcaatgac
     5101 tgagaaaaca gagaaaaagg atgcttctgc ggcctttatt aagtttgcaa ccagtacaga
     5161 atctagtcgt attatgagtt tagggaacag tgttctacct atcagaaatt caacagttga
     5221 tttaattaaa gatgaagtgt cggaaggaat gcaggtatta attaagcaaa accaactttc
     5281 tggacatgcc cgcccagtgg ttgtagctta tccgcaagta tctagagcat tccaacaagc
     5341 agttcaagat attagctact tcgaggaaaa cccagatgta caaaaagtag cagatagtcg
     5401 cgctgctgaa atgcaacagg caattgatac ttcactaaaa tagaagtttc taaagggggc
     5461 caatcaagtg ttaaaaaaac cgacaatgaa agacaatttg ataggttacg gctttctagc
     5521 gccagctttg ctgctgctga cgatttttct gatcataccc gtaatcatgg taatttatta
     5581 tgcctttact gattattatt tgttaacgcc agatgctaga caatttatcg gcttagaaaa
     5641 ttttaagcga ctgttcgctg atccaatttt tgtaaaaagt atttggaaca cggctaaatt
     5701 tgttgtttgg attattccgg tccaaatagg ggcagcttta ggaatggcac ttattatcaa
     5761 caaaaatcgt aaaggaaata tcttttttaa agtagccttt tttgcgccag tcgtgatgtc
     5821 cttagtcgtt atttcgattt tatggttgta cttgttaaat cctaatgaag gtctggttaa
     5881 tacgctattt gcaaagattg gaattgcttc gcagcctttt ttgactagtc ccaaacaagc
     5941 aatgtatacg cttgttttcg tatcggcatg gcaaggtgca ggatatcaga tgctgctgtt
     6001 tttaggggga atgcaaaata ttccgcaaga cgtttatgag gcagccgaaa ttgatggttt
     6061 ttctaagttt cagcaatttc gctatatcac catgccatta ttaaagccca cggcgatttt
     6121 tattttactt accacattga tttcggcctt taaactaatc attcagccaa tggtaatgac
     6181 tcaaggtgga ccaatgaatt ctactatgac aatggtttat tacatttacc aaactggatt
     6241 tacagaccgt atggtaggct actccagctc cattgcgtta atctttacca ctatgattgg
     6301 tttaattaca attgctcaaa gaaaattggt aaaggaggat gatccagcat gaccaagaaa
     6361 tttggaccgc taatgatcgt agaatattgt ttgctgttcc ttttagcggc attattcatt
     6421 ttcccgatgc tgtggatggt agtttcctct atgaagcctg aagcagatgt ctatcaaaat
     6481 ttagcttcct tcaaagcttt tttacctagt ttgaatccag ctaattggtt taaaacttat
     6541 caagaggtta tttcccggtt cagtgtggga acttatttat taaacagtat tttttatggt
     6601 ttaacctttg cctgtgggtc aatcattgta aactctttgg cgggttttgc ctttgcgaag
     6661 gttaattttt caggcaagaa aattatcttt ggagctttgt tagctctgct gattgtcccg
     6721 atggagacgg ttttaattcc gcaatttacc atcgttaatt cactaggctt agtgaatact
     6781 cgcttggcag tgattttacc agcgatggcc agcgcgttta atatctatct gtttagaaat
     6841 ttctttatcg cgattccaga agaaatcatt gaatcagcga aattagatgg tgcaaatatt
     6901 gttaaaattt tctttcacat catgctgcca atgtctaaac cagccatagc cacagtaggt
     6961 gtcttatcct ttatctccag ctggaatgat tatatttggc cgttaatggt cttaactgac
     7021 agcagcaaat tttcaatgca agtggcaatt actacgatca atactacaca gccagtttat
     7081 atcaatcaag tgatggctgt tttaaccatt gcaacgattc cactgattat tgtttatatc
     7141 gttgcacaaa aatatattct gcagggactt ggcggttctg gaacgggtat aaaataggag
     7201 tgaatagtga atgttgcaaa aacttttaaa ggccaatgag tttattgaga aaaatgctca
     7261 aacagtcaat caagaatacc ggaataaatt tcatttgatg gctccgattg gctggatgaa
     7321 tgatccaaat ggttttgttt attatcaaga ggagtatcac ttgttttatc aatattatcc
     7381 ttacgacagc atctggggac caatgcattg gggccatgct aaaagcaagg atctaattca
     7441 ctgggagcat ttgccagtag cactggcacc aggtgaaagc tatgacaagg aaggctgttt
     7501 ttccggcagt gccatagaaa aggatggcaa gctgtatttg atttatacag gacacaatgt
     7561 tgtggaaggg caagttcgac aagttcagtg tttggcagtt tcagaagatg gcattcactt
     7621 tgaaaaatat gccggaaatc caatcatcgc agaagatcac ttagcttctg ttgcaacgac
     7681 cgaagatttc cgcgatccca aagtgtttca gcgaaaagaa gactatttta ctgtagtcgc
     7741 tactaaaact gcagatgctc gtggacaaat tgtgatgttc cattccaaag atttactaac
     7801 ttgggagttt tattccgtat tgctggaggg aactccagaa caaggcattg tatgggaatg
     7861 cccagacttg tttgaactag atggcaaaga agtcttgatt ctttctccta ttcaaatgac
     7921 tccacaaggc aatgcttacc aaaatacgaa ctcaactgtt gctttcatcg gtactgtcga
     7981 ttggcaaaca ggcaaatttc tagtagagaa ttttcatgaa atcgatggcg gtttagattt
     8041 ttatgcaccc cagacctgtg aaaacgaagc aggccaaaga ataatgattg cttggatgca
     8101 aatgtggcag cgtaaaatac ctacgaatga tctgggccat ggttggtcag gttccatgac
     8161 cttgcctaga gagctgaggg tggctgataa tcaattgttg caacggccag tttcatcaat
     8221 ttatcaagta attgatccgc aggaaaggat tgaatgggcg aagactgaag agaatcgctt
     8281 cttactgaag gacttagtat atgaccagca ctatttacgc ttggaaatca atttaaaaca
     8341 ggcaacgaaa ctagaacttc actatgcgaa gggacccgac catacattac tgcttaacta
     8401 tgatgttgaa cgggagtgct ttactgcttc cagggaacac atgccgtatg atttatcagg
     8461 agctgaaaag gaagtgttga aaaagcgcag tgtgacgatt cctttggaaa ataattgtct
     8521 aaccatcgaa attttccgtg atacttcagc tattgagctt tttctaaatg atcgtctgac
     8581 tatgagtaca actttttatg agacagaaaa aggacaggat tttcttttgc tggcagacag
     8641 tgaagtaacc ttttcattgg aaagcggctt aattaatcta tagaagggag agctcagtga
     8701 tgatttatgg ttcaatcgaa gcaggcggca caaaatttgt gtgtgccatt agcgatgaag
     8761 aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa acaatacctt
     8821 tagtcattga cttcttcaaa caataccaag cagatttagc agggattggg attggctcat
     8881 ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc tcgaccccga
     8941 aagtggcatg gcaaaatttt gatttcatcg gtaccatgaa aaaagaattt ccgatcccga
     9001 tttcttggac aacagatgtc aatgcggctg cctatggtga gtatgtcttc ggcagtggca
     9061 aaggattgag cagtgtcgtt tactatacga tcggtacggg tgttggcggc ggtgccttac
     9121 aagaagggcg ctttatcgaa gggtttagtc atccagaaat ggggcatatg ctcgtcgtcc
     9181 ctcatccaaa agatgacttt gctggcagct gtccatttca tggcaactgt ttagaaggga
     9241 tggccgctgg acccgccatc gaaaa
//
LOCUS       DAFELK010000081         9193 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFELK010000081
VERSION     DAFELK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.085"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            497..2038
                     /gene="istA"
                     /locus_tag="LP433_002604"
     CDS             497..2038
                     /gene="istA"
                     /locus_tag="LP433_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003680854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL2006720.1"
                     /translation="MFRYRRILEMHSEGISIRSIAASTGNSRQKITEVIRKAEEKGIA
                     RALSEEMTDQWLGEFLFPEKQLEANGRHLPDFDKIHKELAKPNVTLTLLHQEYAVECR
                     MSGKIPYAYRTFCDYYNAFARKHKATMRIRRKPGEIMEVDWAGSPAYVIDRDTGEKVK
                     AYVFVATLPCSQLSYAEAFLTMKSVAWITAHNHAFEYFGGSTDIIVPDNLKTGVKKNE
                     GIDVILNESYRELGEHYGSIILPARVSTPKDKPSVEGSVGVISTWIIAALRNTHCFTI
                     EDLNREIRMKLNEFNERPFTKKPGSRIRAFEEEEKFALNPLPLAPYKMSVWKKAKVQL
                     NYHVSVESMFYSVPYEYIQQNIDIRMTENLIELYFNSMRIATHKRLYGKFGQYSTVRD
                     HMPDNHKMYVDHTPESSMEWAETIGSSTVKVVQHLLDRYQNEKQALKSIMSLKSFGKK
                     YSKNEIETACSTALNLASLPSVKIIQTILKGNKQKRATSQSHIEDTNIEKHGFTRGAS
                     YFGGK"
     gene            2038..2790
                     /gene="istB"
                     /locus_tag="LP433_002605"
     CDS             2038..2790
                     /gene="istB"
                     /locus_tag="LP433_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBL2006721.1"
                     /translation="MMLNEQTEVKLAELKLSGMLESYREQMTNKEYQSMSFEDRFNLM
                     VDLEHSRRKNNKLQRLIKSANFRNASASIEDIEYHPDRNLDKNLILKLASGTYLEEHH
                     NIILMGASGNGKTYIANAFGIQACRQYYNVKYIRLPELLDELTISKNQADGSFRKIIN
                     RYKKVQLLIIDEWLLTNLSLENSTFLLEIIESRLKTASTIFCSQFHPEGWHEKLGNPQ
                     IADAILDRIIHDSYQILVDGKVSMRERYGIRN"
     gene            complement(2973..3548)
                     /locus_tag="LP433_002606"
     CDS             complement(2973..3548)
                     /locus_tag="LP433_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006722.1"
                     /translation="MKNKFKYLFTILALLPITTSTLITPTIAKASEKQEDSVSYEIVK
                     NDLYIQFEEELAELIASNQSTVSVPDLFSTQSVLSTSSQDNSISEEQFFSLVEKYDGA
                     ELTAVVNSQDAFTTKFVNGGVNSYATSYRGLNALRSELKYNAGALKVGGTLVGTAGGL
                     LGVLLGMVTGDYLSGHCDDAAAGVSAFIQAG"
     gene            4336..4908
                     /locus_tag="LP433_002607"
     CDS             4336..4908
                     /locus_tag="LP433_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HBL2006723.1"
                     /translation="MNKAIFWDLLGTLGGDSRTLINQNFNFFKDTIPALKKAAQSHYL
                     NIIITNQSHISHGRITMAEYTDALESLINELEKNDIQITDVYTCPHARKDNCDCKKPQ
                     PTFVNEALKKYDLNPSKCFVVGDSGKNDMMLAKNAGINSVLLLTGEGIDSLTKYRHLW
                     SETKPTFIAENSLDAINKIHMYADGDSSDS"
     gene            5101..5664
                     /locus_tag="LP433_002608"
     CDS             5101..5664
                     /locus_tag="LP433_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006724.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(5943..6230)
                     /locus_tag="LP433_002609"
     CDS             complement(5943..6230)
                     /locus_tag="LP433_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2006725.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6220..6549)
                     /locus_tag="LP433_002610"
     CDS             complement(6220..6549)
                     /locus_tag="LP433_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2006726.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6854..7183
                     /locus_tag="LP433_002611"
     CDS             6854..7183
                     /locus_tag="LP433_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006727.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(7470..7955)
                     /gene="vanZ"
                     /locus_tag="LP433_002612"
     CDS             complement(7470..7955)
                     /gene="vanZ"
                     /locus_tag="LP433_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL2006728.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(8108..9019)
                     /locus_tag="LP433_002613"
     CDS             complement(8108..9019)
                     /locus_tag="LP433_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBL2006729.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         3057 a         1644 c         1530 g         2962 t
ORIGIN      
        1 tatttacttt tttggttggc ttgttttttg ttattaatag tgtagcaagt tctgattttg
       61 atcttagtaa gattactctt ttaactgtac taccaataat aataggtagt gtgttaattc
      121 ttttttctgt gacttccctt tttagacagc gaggtaattc caaaaagcat tagcgaaaaa
      181 gataaaagca gttttctctt tacccaagag agaactgctt tttatcatct ccacatttct
      241 tgcttaatta attacagctt cataaatact atcaatatgg ctaataggga aaccttcagt
      301 aagggttacc ctagatcctc ctctagtgta accagtgatt acggcatcga aaatgtacca
      361 tctctgcaat aatttttacc aggctcggca aagaaatgta ccagtaagtg caaagcagtg
      421 taccacaaat acctcttgta taatgtaggt gcacacctta gggtgtgaca tttattttac
      481 aggaggtatt tttattatgt ttcgttatcg aaggatactt gaaatgcaca gtgaaggaat
      541 tagtattcgc agtattgcag caagcacggg gaactcacgt cagaaaatta ctgaggttat
      601 ccgaaaagct gaggagaaag ggatagcgag ggcgttgtcg gaagaaatga ccgatcaatg
      661 gctaggcgaa tttttgtttc cagaaaaaca attagaagcc aatggacggc acctgcctga
      721 cttcgacaag attcacaagg aattggccaa accaaacgtg accttgacgc ttcttcatca
      781 ggaatacgca gttgagtgtc gcatgagtgg gaaaatccct tacgcctatc gtacattttg
      841 tgactattac aatgcgttcg cgcgaaagca taaagccact atgcgcatcc gtcggaagcc
      901 tggtgaaatt atggaagtgg attgggctgg atcgccagct tatgtcatcg atcgagatac
      961 gggtgaaaaa gtaaaggctt atgtctttgt ggcaacctta ccgtgcagcc aattgtctta
     1021 tgcggaagca ttcctaacga tgaaatcggt ggcttggatt acggcacata accatgcatt
     1081 tgaatatttt ggcggttcta ccgacataat tgttcccgat aatctaaaaa caggtgtaaa
     1141 aaagaatgaa ggcatcgatg tcatccttaa tgaatcatat cgagagctag gggaacatta
     1201 cgggtccatc attttacctg cccgagtttc tactcccaag gataagccca gtgttgaagg
     1261 cagcgtaggc gtcatctcca cttggattat agctgcctta cgcaatacgc attgttttac
     1321 aatcgaagat ttaaatcgtg aaatcagaat gaaattaaat gaattcaatg agcgaccgtt
     1381 cactaagaaa ccaggatcca ggatcagagc cttcgaggaa gaagaaaaat tcgcacttaa
     1441 tcctcttcca ctggcacctt ataagatgtc tgtctggaaa aaagcaaagg ttcaactaaa
     1501 ctaccacgtc tcagttgaaa gcatgtttta ttccgttcca tacgaataca ttcaacaaaa
     1561 tatagatatt cgaatgacag agaatctaat tgaactatat tttaattcca tgcgaatcgc
     1621 aacacataaa cgtctgtacg ggaaatttgg gcagtattcg actgtcagag atcatatgcc
     1681 agataatcac aaaatgtatg tggaccatac cccagaatcc tcgatggaat gggctgaaac
     1741 catcggttcc tcaacagtaa aggttgttca acacctctta gaccgttatc aaaatgaaaa
     1801 acaagcctta aagtcgatca tgtctttgaa gagctttggt aaaaagtatt ctaaaaatga
     1861 aatagaaacg gcctgttcaa cagctttaaa tctggcttct ttgccttctg ttaaaattat
     1921 ccagaccatt ctaaagggca acaagcagaa gcgagcaaca agccaatcac atattgaaga
     1981 cactaacatt gaaaagcatg gattcactcg cggtgcgtcc tattttggag ggaaataatg
     2041 atgttaaatg agcaaacaga agtaaaatta gctgaattga aactttcagg catgcttgaa
     2101 tcctatcgtg aacagatgac aaataaagag taccaatcca tgagtttcga agaccgcttc
     2161 aacctcatgg ttgatctgga gcattcccgg cgaaaaaata ataaactaca gcggttgatt
     2221 aaatctgcaa actttagaaa tgcctctgcc agcattgagg atatcgaata ccatccggac
     2281 cgtaatttag ataagaacct cattttaaaa ctagccagtg ggacttattt ggaagaacac
     2341 cataacatca ttttgatggg cgcttcaggg aatgggaaaa cgtatatcgc caatgccttc
     2401 ggaatacagg catgccggca atactacaac gtgaaataca tccgactccc tgaactacta
     2461 gatgaattaa ccatctcgaa aaatcaagca gatggtagtt ttcgaaaaat aatcaacaga
     2521 tataaaaaag ttcaattact catcatcgat gaatggctat taaccaatct ttcgttagaa
     2581 aattccacct ttctattgga aataatcgaa tcccgtctta aaacagcatc aactattttc
     2641 tgttctcaat tccatccaga aggatggcac gaaaagctcg gcaaccccca aatcgctgat
     2701 gccattctag ataggatcat acatgattct tatcaaattc tggtagacgg taaagtttct
     2761 atgcgtgaac gttacggcat ccgtaattaa atgagtcatt aaaataaatt aagagccact
     2821 ccatgatttt catgagtggc tcttagttga ccttgtggtc attattgtcg cttttattat
     2881 ttgaaatggt aaccgcgtcg cacttactgg tacatttctt tgcacttagt ggtaaaaaac
     2941 aatgctctag tggtacattt tcgatgccgt attcaaccag cttgaataaa ggcactaaca
     3001 cctgctgctg catcatcgca atggccagat aaataatccc ctgtaaccat gcctaataat
     3061 actcctaaca atcccccagc tgtgccaact aaggtacctc ctactttcaa agcaccagca
     3121 ttatacttca actcgctacg caatgcattt aatcctctgt aagaagtagc atatgagtta
     3181 accccaccat tcacaaattt agttgtgaaa gcatcttgtg aattaacaac agctgtcaat
     3241 tcagctccat catatttttc gactaaagaa aaaaattgct cttcactaat agaattatct
     3301 tgactagaag tagataatac tgattgtgta gaaaataaat cagggactga aacagttgat
     3361 tgattggaag caatcaattc agctaactct tcttcaaact gaatgtaaag atcatttttt
     3421 acaatttcat aactaacaga atcttcctgt ttttcagaag ctttggctat tgtaggagta
     3481 attaaggtcg atgtagtaat tggcaataag gctaaaatag taaataaata cttaaattta
     3541 tttttcattt tttatccttc tttctatttt ttctactttt aataccacaa cttgaaaaat
     3601 aaaaaatcta agcaagagta acatctctta cgtaatgatt ttgcaatagt ttttcctcct
     3661 ctcacaatct attattatgt ttttcgagct gtttcaaaag cacttttcta tttacatctg
     3721 ggaaactaat cgttgctttt ataaaaaaag atgatagcag aaaaaattga acttttcttt
     3781 actataaggt atttataaaa tcatcttcat aggtcaaagt agtagtatta atctcaactt
     3841 tgataagctg gtgtatatca attttctctt taatatgtac aatcattaaa aatagatttt
     3901 tttactattt atggtttcaa ttaacaaaag aacctccaca ctaaatcact ataaatttat
     3961 tatcacctta gttttttatg tgctcctagc atggaaatcc catcaaaaaa gtaaggtttg
     4021 tattcaaatg tttttcgcca acgagggtat cttctttttt acactctttg ctgtatcaaa
     4081 atataactga aattctaagt ctcttctata tcagtgatta tgtgattcga aatatccatt
     4141 ccctcaaaag aagttcatat agaaagtgaa tagagagtgg ctcctgtaaa tatgatatag
     4201 ttaaactggc aaaataaaat atgctttttc aaaaagtaat atttttgttt taattacgaa
     4261 gaactacttt taaatactgt aagcaccttg gcttgttagt taactattct taaaatgaga
     4321 gggagacaaa tatccatgaa taaagctata ttttgggatc tgttaggtac gctgggaggg
     4381 gatagtagaa cactgattaa tcaaaatttc aattttttta aagacacaat accggcctta
     4441 aaaaaagcgg cacaaagtca ttatctaaat atcatcatta cgaatcaaag tcatatttca
     4501 catggacgta ttactatggc agaatatact gatgccttag agagcttaat aaatgagtta
     4561 gagaaaaatg acattcaaat aacggatgta tacacttgcc ctcatgctag aaaagacaat
     4621 tgtgattgca agaagcctca acctacattt gtcaatgaag cattaaaaaa atacgattta
     4681 aatccaagta agtgtttcgt agtaggcgat tccggtaaaa acgatatgat gttggccaaa
     4741 aatgctggta taaacagtgt tttactttta acgggagagg gaattgatag tttaaccaaa
     4801 tatagacatc tgtggagtga aacaaaacct acttttattg ctgaaaacag tttagatgct
     4861 ataaataaaa tacatatgta tgcagatgga gactcttctg attcatgata ccagaagagt
     4921 ctccatttat tactaaaaac cgtatcaaaa acaatcgatt atgagacaaa atgaaatgac
     4981 ctcttttatt aaataaaaga ggtcatattt tgtatcataa cttgttgcat taactatgta
     5041 tctataactc ccttttatga tacaatcaag ccagaattaa agtacgaaag gaagaaaagc
     5101 atgagtggat acatttatgg ttatgcccga gtgagtacac gttcacaaga actaaatcgt
     5161 caattagact tactcaatga acaaaattgt aatgaaatcc taactgagaa aatgacggga
     5221 accaaagcgg ttcgtcccca actaaatcgt ttaaaagata aaattcgtcc gggagatacg
     5281 gtaattgtag aaagtttttc tcgattgggt cgtagtacaa aggatttgat tgaccttgtt
     5341 acctattttg aagaacacca tgttaagctg gtgagcttga aagaaaactt cgataccagc
     5401 acgcctcacg gacgcttaat gatgactgtc ttccaagcat ttagtcagtt cgaacgtgat
     5461 ttaattgttg aacgtaccaa agaaggtttg aaaagtgcac gtgcgagagg tcgtaaaggt
     5521 ggccgtccac gagtgaacca gaaagatgtt gatcgagcag taaaattgta taaaagtcag
     5581 gtttatagcg taaaagaaat tacggaaatg actggtatta gcaaggcaac actctaccgc
     5641 tacttaaaag acaataggga ataatctatt ttaatcttta ggaatctata atatttatgg
     5701 gagaattaga gtgatttttt tattattact aaaaaacaat ataaaataac gcattttaag
     5761 ccctctttgt gcataaggat gaagctttta atttgaaaga ggcttaaaat gcgttttaat
     5821 tttttctatt tttcataaat atataggtta gtggtttaaa attatagggt attacaactc
     5881 tcagctgtta aaaattatct tttaaagtgt cgtctatcct ctcaagttga aacattgggt
     5941 tcttacctaa tcttttttaa ttgttcataa aaattttcat gcgttccaca tagtaagata
     6001 ggtatcactg cattatcttt aatttcatat gcaacgcgat atgtcgtacc tgcatacttg
     6061 aatccaatag cccaaattcc tgataaatca cccgtttttt gttctcccga atgaggacga
     6121 actgctatct catcataaat tatcgttaaa aattgttctt ttaatgtttt ctcttttaat
     6181 ttttttagat actttattac gtgtttagaa ggtagaatct cataagccaa tttctgctgc
     6241 caactcctct tttgtcatcg gtttagaatt tgcaacagta tcttcagcaa tagatttaaa
     6301 tgcagaagtt aacgcatttt ttctatttct aaattctttt aagatctctt gtttgctata
     6361 accttctgaa agaatatcag ccaaaatatc ttcactaaaa tcaaaaaatt cttttttagg
     6421 ctctacaaac tcataaagga taccattctc tacaagctta gcttctactt caacaccatt
     6481 gggcacatcg aattctttag ggaccgttaa cataatagaa tttccttgtt ttcttgtttt
     6541 tgtaatcata ttatttcctc cattatttta catttcgtaa ttacttagta attacattgt
     6601 acgctatttt tagtagaaat acaaaataat aaaactcctt tagaacaatt ttcaaaggag
     6661 ttttatttga ttaggaaatt atgtagaata ataatatgtt tttaacttgg aatcaaaaac
     6721 gcacttgcaa gtaagtttac ttcaatacat gaaattgctt ataatagtgt attggaatta
     6781 aggtagattg acaaaagagt gatcaaatag gtatacttca ttcaaataat cgtttgaatg
     6841 tgaggtgaga tgaatgaaaa aagtttgcca agtgactgtc gtacataaag aaaaagtaaa
     6901 tggaataaaa aataaattgg atcaaaaaga tttttcaaac ttacttgtgt tagggaaatg
     6961 tttcagcgat ttttctagaa ttaaaatttt ctatgcttta gaaacctata aggaaatgtg
     7021 cgtctgtgat ttagcagaaa tacttactgc tagtgtcgct acaacgtcac accatttacg
     7081 ttttttaaaa aaacatggaa tggcaaaatc acgtcaagat ggaaaagtag tttattactc
     7141 tttagcgaat gaagacatcc tttccgctat tcgtgttttt taaagttatc agaaaatcta
     7201 tctatgaaat cttagtttgg gggtaccgtc aggaaaatgc ggatttacaa cgttaaggaa
     7261 atttattaaa gagaccaatt cctcagcact aaaattgata attgggcttt ctttgttact
     7321 atagtgttag gtaagctttt tactttatca ccggttttcc cctcacttca cacctacggg
     7381 cgagtttccc cacatcccgt tttccatcta atccaattca ttcaatatct ttatgtgtat
     7441 gaaagatcag attgcttgat ttagacatct tacacgtaat ttattcttaa atgggtacgg
     7501 taaacgagca ataatacgag caaaagtata cctacaaaaa taataactct gtctaatttt
     7561 ttttgattca tatgcttatt gcttaaacca tataatttca gtccaagaaa gcctccaaca
     7621 gtatttgtaa ttacatctgt tatgtctgtc gctccaatag cgaagataaa ttgaattatt
     7681 tcaaaagtaa gacttaaaac cagtacaaaa gcaaacttag gtaaaaatcc gatttcttta
     7741 aaattgacat tcaaaagcaa gccaaatgga ataaagatta taacattatc tatcatctct
     7801 ctgaaattcc cagtagcagt aaatggagtc aagttaagac ttctttgatg ataattaaat
     7861 actgataaaa tattgtattg taatttgaat aacactaacc agattagtgt cactaaatat
     7921 aaagctagca atcctctaga taatattttt cccaatataa tttcctctaa ttcttttgtt
     7981 taagttgtat cattagtata gcaatgtcct agttaacgtg ggttttaaat taaaaagcta
     8041 acgttacccc aaaagtgcta gtacaataat gctgttcatt aatttcgttg gtttcattcc
     8101 gccatcctta cctccttgaa ttagtatgtg ttgatccggg aaacactgtc acaattacac
     8161 cgtctatatt gtttcctgat atctcataac gaagattagt cggcacatga atggtggtat
     8221 ttttagtaac aggataataa aagatctcat atttttcccc atttacacta acagaaatgg
     8281 ttttttcttc ttttaggtaa tccatatatt cctcgagaac gaaattcttt tctttcataa
     8341 tcgcactatg tggtaaacca acatagcgaa tatgccatgg ttcatattga attcctgtta
     8401 actctgtttt gtcctctgga taacgtaaaa tgaacccgta tttccaagca ttttcttcta
     8461 tccactttcc ttcaggggct cgttccattt tcgtcaagct tgatcctaca tctagtgata
     8521 aacctgaatt atgctcacta taacctgctg gtaaggcata ctcagccccc atttcttggt
     8581 aaagcacact ttgctcatca aagtctcgat agccactatt aataataaaa tgactaacgc
     8641 caccctttac agcatcattg accatctctg aaaatttttg tgctatttct tttgacatat
     8701 aaatattact atcaagcaac ccgtatccat ttattaattc gtcatgttta gataaattca
     8761 cgatatctga cttcacactt tcttggcgaa caggatattt actattgatt aatagcagat
     8821 ttccttgata aacctgttct tctgtaattg ttttctcttg ggtattttca gaagtcccac
     8881 tattttctaa atgttctttg ggattttgat cataattttg aaattcgact ttttcctgag
     8941 aaaacagtgc ttcattaacg tagtcataac ctaagtatat taagaataac aataacaata
     9001 aaaaaaacaa cttcttcatt ttcagtctcc tccttaacta tatagttgga agtatgaaat
     9061 atttctagaa tcttcccctt aaacggcaca atctcgtttg agattgtgcc gttttgcccc
     9121 gtaaattaca gtcaattatt tcgccctact ggatttacta ttatcaccaa tgtagatgaa
     9181 ttttcataag tga
//
LOCUS       DAFELK010000082         9081 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFELK010000082
VERSION     DAFELK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.086"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..278)
                     /locus_tag="LP433_002614"
     CDS             complement(<1..278)
                     /locus_tag="LP433_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2006730.1"
                     /translation="MSITKNIKCTDEKTSHSIKQILNIKDSHITFSKDAISKERVHGR
                     MANVFTGLLTGEAHRCECCGFDSVIRHAYHDSWIQLLPYQEVPTYLHL"
     gene            complement(426..984)
                     /locus_tag="LP433_002615"
                     /pseudo
     CDS             complement(426..984)
                     /locus_tag="LP433_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302360.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1153..3264
                     /locus_tag="LP433_002616"
     CDS             1153..3264
                     /locus_tag="LP433_002616"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012579.1,HMM:NF013070.1,HMM:NF019826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2006731.1"
                     /translation="MNTKDLKLLETIVRSHVTNSQQLKSLVHFSTRQITYSIKKINDE
                     LSLHGLSLIKRSNSGEWLYEANDLQKLLIYMNQAMVFKEGAIPEYINDDLAYSEIRRY
                     SELLFILANPKKVTTQEIMAFIGISKNTARNDFSKIKKELPPDYTLIFDPQNGYMIES
                     SMAKLHTLLLEVFNYLFERHATVNRFESLFSEEREFVGFFIHTYEQTFKLKFSDNSLT
                     KLYYLIGLSLSSFKRRTKGQIDFSYDLQELDEFQMIRSCIDQHYQHAEIAIDYEWLTL
                     LFLSFNTISNEFEILDSRIYQVIMEMITLFQSKSAIRISNKEELTNRLMNHLRPAIYR
                     IRYELPFEIDDLAEIVKENHEVSAVLNFVKESIVPLEAFLRKTIPETELYLISVYFCS
                     ELLNSSIIETPVRKKAIVVCSNGLIMANVMAKTLKEIFPDIQFVASSSVREMDKFVED
                     VDLIFSNQPLKSEIPLYIIQPIMNEEEKNRLRNRVLIDFSTNNISKETRNLTEIIKRY
                     SAVQNEESLQTDIERFLINYANSLIYLDRQSKQAQKISFVELLVSEGIILVSTKQLTW
                     QNAMELSCQPLLKEQVINQNYQTILMSQMADEEAYYFLNNRIAIPHSSPENGVIKGGC
                     SLLISVDPIIFPGNRPIHFISPFAIGKKENYLLAINQLLQLSKDEEYQQEILLCTTED
                     EVRKKIKNFLRRKQYVNNEFS"
     gene            3242..3892
                     /locus_tag="LP433_002617"
     CDS             3242..3892
                     /locus_tag="LP433_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBL2006732.1"
                     /translation="MSITNFPELTIILRGYSFEEAMFVMEELAAMNTSVGIEVTTNND
                     DFARIITEGNKKFGQQLLIGAGTVLTFSQADQAIAGGAKFLLGPKKFSTPIFSLAKER
                     GVVTVPSAFTPSEIQVMFDEGADIVKVFPAVTVGPTYFKQLAGPFGIRPLMAVGGVTI
                     DNIAAFKKAGVVYFGVGSSMFQKADIQNRNGQAIRKSIQSYLDKLAEAGSEEDESH"
     gene            3879..4331
                     /locus_tag="LP433_002618"
     CDS             3879..4331
                     /locus_tag="LP433_002618"
                     /inference="COORDINATES: protein motif:HMM:NF012579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2006733.1"
                     /translation="MSLIKLEEKNILLNQSFSNQEEYFQKITKKLMTENMVKEGYLES
                     ITKRETTYPTGLYIGERSIAIPHTDYQLSNVTAILVSVLKDSLHFQRMDDPEEMVSVN
                     VIIHLLFDSPDKQPQLLKELMSKVTNQDFLQAIMEAKSKTEVLTAFNQ"
     gene            4348..4653
                     /locus_tag="LP433_002619"
     CDS             4348..4653
                     /locus_tag="LP433_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIB"
                     /protein_id="HBL2006734.1"
                     /translation="MSKKTIIVACASSMITSTMAANKIRKIAKTNGLPEPRILQLKFS
                     EVAGALESNQVDFIVPTGKLQENVTKGIKVIPGTPFVTGVNEEKSESLVLEALKELD"
     gene            4665..5942
                     /locus_tag="LP433_002620"
     CDS             4665..5942
                     /locus_tag="LP433_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010492829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IIABC"
                     /protein_id="HBL2006735.1"
                     /translation="MNIVIDALNWISSLGPMIMMPIIILILGLFFRIKLNTLLKSALT
                     VGIGFAGVNIIINWFISQVGPSVQLMVKNWGIQTSIMDVGWPARAAATWSFPLAAVMV
                     FIILGINVLMLIFKKTNTVMVDFWSYNHYIFVAALVYYATDKNIILAVIFGAIDAIIS
                     FKLADWTTPLVEDYFELEGVNFPTANSVGWAPLAWLLNKLWDRIPGLNKVDARPEKIQ
                     ERFGFVGEPMFMGFVIGLVIGLLAKEPVDKVLIVGMSTSATMVLTPKMMQILMEGLLP
                     FANSVKKFLNVKFPGNNFTMGVDAALTVANSSAIATGIIMVPITLVLAAILPGNKLLP
                     ISDIAYQAMWLSAWPVAFSKGNIIRGILSTTIITACVLLIATSLAGIHTQLALAGGFQ
                     LPAGMTQISTEDAGTHIIGFILMKIAEFISNIF"
     gene            5961..7109
                     /gene="dgoD"
                     /locus_tag="LP433_002621"
     CDS             5961..7109
                     /gene="dgoD"
                     /locus_tag="LP433_002621"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HBL2006736.1"
                     /translation="MKISKITVYKVKPRWIFVKISTDEGIEGWGEMISGTKTETVVAG
                     AYEIGNRFLVGQNPFAIERLFQEMHRSFFRGGPINGTIVSGLEMALWDIKGKALNVPV
                     YELLGGAARDKIKVYSWIGGDRPSEVVEQAQDRVDRGFTAVKMNATEELHYIDSYEKV
                     AEVVERVASIRERFGDTLSIGVDFHGRVHKPMAKVLAKALEPYHPMFLEEVVLPENEE
                     HFSEVANAVAVPLATGERLYTRWQFKSILQQGAIDIIQPDVALCGGILETRKIAAMAE
                     AYDIAVAPHAPYGPIALAATLQVDSCTPNVFIQEQSLGIHYNKGFDLLDFVKNKEIFQ
                     YKDGFVDLPTKPGLGLEMDEDRVKEIAQEGLVWTNPKWKNYDGTIAEW"
     gene            7121..8023
                     /locus_tag="LP433_002622"
     CDS             7121..8023
                     /locus_tag="LP433_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryldialkylphosphatase"
                     /protein_id="HBL2006737.1"
                     /translation="MINTVTGPIEAESLGTTFIHEHLYVIPNELRKYEDYTLDDIYHS
                     IAEVMAFKQAGGKTIVDLTPINYGRNPLALKMISEATGVNVAFVTGFHKEEFQPKWLT
                     TLNDDEIFELLYSEITHGVTSQNLLPGAMKVGTSKNEVTLAEQRILAIAGQVQKKTGI
                     PIITHCDGGTMGLEQINCLTKNGAKASNICLSHVDLTKDFHYLAQICETGASICMDHI
                     GRELANHDADRVQLIKRLVDAGYENQICLSGDMGRKKYLPTYGGTPGLTYILTSLKEE
                     LLKVMSEPTFNKMIEMNPINILSK"
     gene            complement(8692..>9081)
                     /locus_tag="LP433_002623"
     CDS             complement(8692..>9081)
                     /locus_tag="LP433_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2006738.1"
                     /translation="FKQFPLFQGKYMTESEVLDYLLSIDNQLRQSYEVYQELLAAFDA
                     KDFTEFFNLIESLPHSLNDGFKKAICYLKKHTEAITNSLKYPYSNGKLEGKNNLIKVI
                     KRIAFGFRTFRHLRMRVLIQQNICEII"
BASE COUNT         2947 a         1398 c         1854 g         2882 t
ORIGIN      
        1 tacaggtgta gataagttgg tacttcttga tacggaagca actgaatcca actatcatga
       61 taagcatgac ggatgacaga atcaaaccca caacattcgc aacgatgcgc ttctccagtt
      121 aataagccgg taaatacatt ggccatacgg ccatgaacgc gctctttact aatggcatct
      181 tttgaaaagg taatatggga atctttgatg ttcaaaattt gtttgatgga atgacttgtc
      241 ttttcatccg tacatttgat attcttagtt atggacattt ggttatcctc ctatgattgt
      301 ttttgccgat ttaattatag gacaaccaga tgtctttttg ttataaaaaa atatttggcg
      361 tcactactca gtttgagtaa caaaaccaaa tattatagaa ccggcttttt cagttttttc
      421 ccttcacaaa caacatcgat gattttctcg gcatgggtac gggtatcatt cattaattct
      481 gtatcggttg gatatttgat gttttgtgga gcacaagtgg catccaaaat caatgttccg
      541 gaattgaaat cgtcataaga atcgttgtcc ttatcgtctt ttttcttgtc gaagacgagt
      601 attttttcat tgatttctat caacgttgtt tcgtccaagc gtttccggaa atagaccatt
      661 gtagagcatc gaaaggcttg gcatcttgat agcccggcaa accgatgaag aactataaat
      721 acgggttttc ttgaatttgt aagaccgttt cttcgtcgct atagctatat tccttttgaa
      781 tcagtagagc tccgaaggtc atgcgaaagg gttttgcgac gtttcctttt ttttacgaaa
      841 acttttagcg tagtcttttt caagttcagc ccatggaatg agctctgctt tttgaatcca
      901 acggttagac ggattcattt tgagacctat cggttgattg aaatcttcaa aagccaattg
      961 aacggttgtt tgtaatttat acatgaaaag cctccaaaat tgagtggtac tccacaccat
     1021 tctgatggtg cataagataa aaaattaaag aagtgcctgt catttgtctg atttaagcca
     1081 aggtttgaca aattttggat attccaatta atactgtaag cggttatatt taactcaggg
     1141 aggtagatga atgtgaatac aaaagattta aaactgttag aaaccattgt acgatcacat
     1201 gtgacaaact ctcaacaatt gaaatcatta gtacattttt cgactaggca gataacttac
     1261 tctataaaaa aaattaatga tgaattatcc cttcatggat tgagtctgat aaagcgaagt
     1321 aactcagggg agtggttata tgaagccaat gatcttcaaa aacttttgat atacatgaat
     1381 caagcaatgg tttttaaaga aggtgcgatt cctgaatata taaacgatga tttggcttat
     1441 agtgagataa gaagatattc ggaactgtta tttattctag ccaaccccaa aaaagtgaca
     1501 acccaagaaa taatggcgtt tattggtatc agtaaaaata cggctagaaa cgacttttct
     1561 aaaataaaaa aagagttgcc accagactac actttgatat ttgatcccca aaatggctat
     1621 atgattgaat caagcatggc aaagcttcat acattgctct tagaagtttt caattattta
     1681 tttgaaaggc atgcaacagt taaccgtttt gagtcactct tttctgaaga aagggaattt
     1741 gttggttttt ttattcacac ctacgaacaa acttttaaat tgaaattttc tgataattca
     1801 ctaaccaaac tttattattt gataggttta tcactttcta gttttaaaag aaggacgaaa
     1861 ggacagattg attttagtta tgatttacag gaattagatg agtttcaaat gattcgaagc
     1921 tgcattgatc aacattatca acatgctgag atagctatag attatgaatg gttgacgctt
     1981 ctgtttttat cattcaatac aatttcaaat gagtttgaaa ttttagattc aagaatctat
     2041 caagtaatta tggagatgat taccttattt caaagtaaat cagctattcg gattagtaat
     2101 aaagaagagt tgaccaatcg attgatgaat catttacgac ctgcaatcta tcgaattcgc
     2161 tacgaattac catttgaaat agatgattta gctgaaattg ttaaggaaaa ccatgaagtt
     2221 agtgcggtac ttaattttgt taaagaatcc attgtacctt tggaagcatt tttgcgtaag
     2281 acgattcctg aaactgaatt atatttgatt tctgtttatt tttgttcgga gctattaaat
     2341 tcttctatta tcgaaacacc tgttagaaaa aaggcaatcg tcgtatgtag caatggattg
     2401 attatggcca atgtaatggc gaaaacattg aaagaaattt ttccagatat tcagtttgtt
     2461 gctagttctt cggtcagaga gatggataag tttgtcgaag atgttgattt gatttttagc
     2521 aatcaaccat tgaaaagtga aattccatta tatattatac aaccgattat gaacgaagaa
     2581 gaaaaaaacc gcttgcggaa ccgtgtactc attgattttt ctacgaataa tatcagcaaa
     2641 gagactagga accttactga aattattaag cgttactctg ctgttcaaaa tgaagaaagt
     2701 ctacaaactg atattgagag atttttaatt aattatgcaa attcactaat atatctagat
     2761 cgtcaaagta aacaggcaca aaagatatct tttgtggaat tgcttgtttc tgaagggatt
     2821 attcttgtat ctacgaaaca acttacttgg cagaacgcga tggaattgtc ttgtcagcct
     2881 ttattaaagg agcaggtaat taatcagaac tatcagacta ttttaatgag tcaaatggcg
     2941 gatgaagagg cttattattt tcttaataat cgtattgcta ttccacattc atcgccagaa
     3001 aatggggtaa ttaagggcgg ttgctcgtta cttatatcag ttgatccaat tatttttcct
     3061 ggaaataggc ctatccattt tatttcccct tttgcaattg gaaagaagga aaattattta
     3121 cttgcgatta accaattact acaactttct aaggacgagg aatatcagca agaaatactt
     3181 ctttgcacga cggaagatga agtgagaaaa aaaataaaaa attttttaag gaggaagcaa
     3241 tatgtcaata acgaattttc ctgaattaac catcatttta agaggatata gttttgaaga
     3301 ggcgatgttt gtcatggaag aattggctgc gatgaacact tcggtaggaa ttgaagtaac
     3361 aaccaataat gatgactttg cacgtatcat cacagaaggc aacaaaaaat ttgggcaaca
     3421 attattgatt ggtgcaggga cagttttaac attttcacaa gcagatcaag caattgctgg
     3481 tggtgcgaaa tttttattag gaccaaaaaa attttcaaca ccaatttttt cgttggctaa
     3541 agaacgtggg gtggtaactg tgccatcagc ttttacgcca tcggaaattc aagttatgtt
     3601 tgatgaaggt gccgatattg taaaggtttt tccagcagtc actgtagggc caacctactt
     3661 taaacaactg gccggtcctt ttggtatacg gcctttaatg gcagttggag gagtgacgat
     3721 tgataatatt gcggctttta aaaaagcagg agttgtgtac tttggggtag gatcaagcat
     3781 gtttcaaaaa gctgatatac aaaaccgcaa tgggcaagct attcgaaaat caattcaatc
     3841 atatttagat aaactagctg aagcaggaag tgaagaagat gagtctcatt aaattagaag
     3901 aaaaaaatat tttgttaaat caaagttttt caaaccaaga agaatacttt caaaagatta
     3961 caaagaaact gatgacggaa aacatggtaa aggagggata tctcgagtca atcactaaga
     4021 gagaaacaac ttatccaacg gggctatata ttggggaacg ctcaatcgca attccacata
     4081 cagattatca gttatcaaat gttaccgcta ttttagtatc cgttcttaaa gatagtttgc
     4141 attttcagcg aatggatgat cccgaagaaa tggtttcagt gaatgttatt attcaccttt
     4201 tattcgatag tcccgataag caaccgcaat tattgaagga gttgatgagt aaagttacca
     4261 atcaggattt cttacaagca attatggaag caaagagtaa aacagaagtt ttaactgcat
     4321 ttaatcaata aattggaggg aaatacaatg agtaaaaaaa caattatcgt cgcatgtgca
     4381 tcatcaatga ttacatctac aatggcagct aataaaattc ggaaaatagc aaaaacaaat
     4441 ggattaccag aacctcgaat tttgcaacta aaattttcag aagttgcagg tgctttagaa
     4501 tcaaatcaag ttgactttat cgttcctaca gggaaattac aagaaaatgt aaccaaagga
     4561 attaaagtta tacctggaac accatttgtt actggagtga atgaagaaaa atctgaatct
     4621 ttggtgttag aagcattgaa agagcttgac taggagggtg aaaaatgaat attgtcattg
     4681 atgcgttaaa ctggatctca agtttgggtc cgatgattat gatgcctatc attatcttga
     4741 ttttaggatt attttttaga attaagctaa atacattact aaaatcagcg ttgactgtgg
     4801 ggattggttt tgcgggtgta aatattatta ttaattggtt tatttcacag gtaggtccat
     4861 ctgttcagtt aatggtcaaa aattggggta ttcaaacaag tattatggat gtcggctggc
     4921 cagctcgtgc agcagccact tggtcttttc ctctagcagc agttatggta tttattattt
     4981 tgggtattaa tgtgttgatg ctgattttta aaaagaccaa tacagtaatg gtcgatttct
     5041 ggagttataa tcactatatt tttgtagctg ctttggttta ttatgcaacg gataaaaata
     5101 ttatattggc ggtaatcttc ggggcgattg atgcaattat tagttttaaa ctcgctgatt
     5161 ggacaacgcc gttagtagag gattactttg aactagaagg ggttaatttc ccgactgcga
     5221 actcagttgg ttgggcaccc ttggcttggc tacttaacaa attgtgggac cgcattcctg
     5281 gattaaataa ggtagatgct cgtcctgaaa aaattcaaga gcggtttggt tttgttggtg
     5341 agcctatgtt tatgggattt gtcatcggct tggttattgg gttattagca aaagaacctg
     5401 ttgataaggt attgatagtg ggaatgagta cttctgcaac aatggttcta acacctaaaa
     5461 tgatgcaaat tttaatggaa ggattattac cctttgctaa ttctgttaag aaattcttga
     5521 atgtaaaatt tccaggaaac aattttacaa tgggtgtgga tgctgcgttg acagttgcta
     5581 attcaagtgc cattgctacg ggtattatca tggttccgat taccttagtg ttggctgcta
     5641 ttttaccagg taacaaactc ttacctattt cagatattgc ctaccaagca atgtggctat
     5701 ctgcatggcc ggtcgccttt tcaaaaggaa atattattcg cggaatactt tccaccacga
     5761 ttataacagc ttgtgtgctt ttaattgcta ctagtttagc cggcatacat acacaattag
     5821 ctttggctgg gggattccaa ttaccagcag gaatgacaca aatatctacc gaagatgcag
     5881 gtacacacat tattggtttc attttaatga agattgctga gtttatttca aatattttct
     5941 aatattcagg agggcataca gtgaaaattt caaaaattac agtctataaa gtaaaaccaa
     6001 gatggatttt tgtcaaaata tctacagatg aaggtattga aggctggggt gaaatgattt
     6061 ctggaactaa gactgaaaca gttgtggcag gagcttatga gataggaaat cgattcttag
     6121 ttggtcaaaa cccatttgca attgaacgtc tgtttcagga aatgcatcgt tcatttttcc
     6181 gaggtggtcc tattaatgga acgattgtct ctggacttga aatggcttta tgggatatta
     6241 aagggaaagc cttaaatgtt ccagtttatg aattactagg tggagcagcc cgtgataaaa
     6301 tcaaagtata ttcttggatt ggtggagatc gtccttctga agtagtagag caggcacaag
     6361 atcgagtaga tcgtgggttt accgccgtga aaatgaacgc gacagaagaa ttacactaca
     6421 ttgattctta tgaaaaagta gctgaagtag tggaacgtgt tgcttcaatt agagaacgtt
     6481 ttggagatac attgagcatt ggtgtcgatt ttcatggtcg tgttcacaaa ccaatggcta
     6541 aggttttagc aaaagcactg gaaccctatc atccaatgtt cttagaagaa gtggttttgc
     6601 cggagaatga agaacatttc agtgaagtag ccaatgcagt tgctgtacca ctagcaacgg
     6661 gtgaacgttt gtatacaaga tggcaattta aatcaattct tcaacaggga gcgattgata
     6721 tcattcaacc agatgtagct ttatgtggag ggattttaga aacaagaaaa attgctgcaa
     6781 tggctgaagc ttatgatata gcagttgccc cccatgcacc atatggaccg attgcgttag
     6841 cagctacatt acaagttgat tcttgtacac ctaatgtgtt tattcaagaa caaagcttag
     6901 gtattcatta caacaaaggg tttgatttgt tagattttgt aaagaataaa gagatattcc
     6961 aatacaaaga tggcttcgta gatcttccga caaaaccagg tttagggtta gaaatggacg
     7021 aagatcgagt gaaagaaatt gcacaagaag gtttagtttg gaccaatcct aagtggaaaa
     7081 attatgatgg tacaatcgct gaatggtagg agatgagtgc atgatcaata cggttacagg
     7141 cccaatcgaa gctgagtctt tgggtacaac atttattcat gaacatttat atgtcattcc
     7201 taatgagtta agaaagtatg aagattatac cttggatgat atttatcata gtattgcgga
     7261 agttatggct tttaaacaag ctggtggaaa aactatcgtt gatttgacac caattaatta
     7321 tggacgaaat ccgttagctt tgaaaatgat atctgaagct accggagtga atgtagcatt
     7381 tgttacggga ttccataagg aagagtttca gccaaaatgg ttgacaacgc tcaatgatga
     7441 tgagatcttt gagttgcttt attccgaaat aactcacgga gtcacttcac aaaacctttt
     7501 gccaggagca atgaaagtag gtacgagtaa aaatgaggtt acattggctg aacaacgaat
     7561 actagccata gccggtcaag tacaaaaaaa aacagggatt cccattatta cgcattgtga
     7621 tggggggacg atgggactgg agcaaattaa ttgtttaaca aaaaacggtg cgaaagcaag
     7681 taatatttgt ttgagtcatg tagatttaac taaagatttt cactatttag ctcaaatctg
     7741 tgaaacggga gcaagtattt gtatggatca tattggccga gagttggcga atcatgatgc
     7801 agaccgcgtc caactaatta aacgactggt tgatgcgggt tatgaaaatc agatttgtct
     7861 ttcaggtgat atgggacgaa aaaaatattt gccaacttat ggaggaacgc ctgggcttac
     7921 ctatatttta acaagtttga aagaagaact attaaaagta atgagtgaac caacttttaa
     7981 taaaatgatt gagatgaatc caattaatat actgagtaag tgaagtcaat tgaatcattc
     8041 agaagaacta atgaaattag ttgctttcgc agggttaatt cttctctctg ggtttggaaa
     8101 agagggctta gcttcggatt ccctagttaa actaggggtt ttatcaggtt attgtactga
     8161 ttataagtac ctgaattatt catgaaatac tttttccgtc gttttatagg cagttgggtc
     8221 aataaaaaga tcagaaaaac gaacgagaga ctctcataac gtgccactaa ataaaaatcg
     8281 tacgttattt taaaaaatgg gttgattcta ggcagtactt tgtcggtcta tttttagaaa
     8341 aagaggttct ttgtcaaaca tacatgaatt cgcaagctca ttcaccctga aggatgaaag
     8401 gcagaaactg tagtatacta atggtggaaa ggaaaaaaag ccgccagcaa tttggaaaag
     8461 aacgttatgt cgattgtcaa actggcttgc tttatttctc gagaaccctg aaatatagcc
     8521 aatgagcatg tgtataaaaa attgatttta tatgaaataa agcactcctt tcctaaaatt
     8581 attggaaagg agtgcgtttt ttatggaaat tatttaggtt ctttgtcaat tgctattgtt
     8641 ttgctcaaat cgtatgttag gaaatgcttc ggcatttcct tttttgcgtt attaaatgat
     8701 ttcacagatg ttctgttgaa tcaggacacg catccggaga tgacgaaaag tccgaaatcc
     8761 aaaagcaatt cttttgatta ctttgatgag gttattcttt ccctccaatt ttccgtttga
     8821 atagggatat tttaaggagt ttgtgattgc ttctgtgtgc tttttcagat aacaaattgc
     8881 ctttttaaac ccatcattca aggaatgtgg caatgattca atgagattga aaaattcagt
     8941 aaaatctttt gcatcaaaag cagctaataa ctcttgatag acttcatagc tttgtcgtag
     9001 ttggttatct atagagagta ggtaatcaag cacctccgac tccgtcatgt atttcccttg
     9061 gaagagggga aattgcttaa a
//
LOCUS       DAFELK010000083         8436 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFELK010000083
VERSION     DAFELK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8436
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.087"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..950
                     /locus_tag="LP433_002624"
     CDS             <1..950
                     /locus_tag="LP433_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006739.1"
                     /translation="YYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQLDKKGQSELQAG
                     IQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNTRNTPTQHLATS
                     IHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTLEKAIPYIAAWTKNGQTLD
                     DKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQEHKNTVETAEQK
                     NIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGKSYGKEIQTALP
                     SEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            1011..2480
                     /locus_tag="LP433_002625"
     CDS             1011..2480
                     /locus_tag="LP433_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL2006740.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVGDDRLDHAVAFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFN
                     LKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRR
                     KQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKAT
                     YEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKE
                     ACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEF
                     VPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2491..4500
                     /gene="topB"
                     /locus_tag="LP433_002626"
     CDS             2491..4500
                     /gene="topB"
                     /locus_tag="LP433_002626"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL2006741.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKRSEGFI"
     gene            4616..4765
                     /locus_tag="LP433_002627"
     CDS             4616..4765
                     /locus_tag="LP433_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006742.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4846..5442
                     /locus_tag="LP433_002628"
     CDS             4846..5442
                     /locus_tag="LP433_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL2006743.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            5455..6354
                     /locus_tag="LP433_002629"
     CDS             5455..6354
                     /locus_tag="LP433_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL2006744.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            6357..6488
                     /gene="ssb"
                     /locus_tag="LP433_002630"
     CDS             6357..6488
                     /gene="ssb"
                     /locus_tag="LP433_002630"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2006745.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            6510..6842
                     /gene="ssb"
                     /locus_tag="LP433_002631"
     CDS             6510..6842
                     /gene="ssb"
                     /locus_tag="LP433_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2006746.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            6864..7121
                     /locus_tag="LP433_002632"
     CDS             6864..7121
                     /locus_tag="LP433_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006747.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(7280..7402)
                     /locus_tag="LP433_002633"
     CDS             complement(7280..7402)
                     /locus_tag="LP433_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBL2006748.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            7592..7816
                     /locus_tag="LP433_002634"
     CDS             7592..7816
                     /locus_tag="LP433_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006749.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRNQLVIESMQIRNPDHFTRLMGI"
     gene            8264..>8436
                     /locus_tag="LP433_002635"
     CDS             8264..>8436
                     /locus_tag="LP433_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL2006750.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGD"
BASE COUNT         3057 a         1466 c         1776 g         2137 t
ORIGIN      
        1 cttactacac gattgaaaaa gtgtttgata tcacacaaac acagttaaaa cctgaagact
       61 atccgaaaat ctttccgaac cgtgtctttg attttcaatt ggataaaaaa ggacagtcag
      121 aacttcaagc tgggattcaa gcggtagcca acaatattgg aatacaaatt cgagatatga
      181 cagaaagtga agtctatcaa agagaattag gacaagcacg tggggcgtat gttcgtaacg
      241 aatttactgg cgaagaagaa atcgtcatga atactcgaaa tactcctacg cagcatttag
      301 ctacaagtat tcatgaatta gcccatgcaa gaatgcacaa attttcagaa ttagataccg
      361 caactaaaga attgcaggca gaaatgactt cttatattgt gtgcaaacat tttggaatgg
      421 acacgttgga gaaagctatt ccttatattg cagcatggac gaagaatggt cagacgttgg
      481 atgataagga agctgcggaa cgtgggaaaa tcatgaatga tgtcagccgt gtcgcaaatg
      541 aattcattca aaccatttct aatgaaatca atcaatacag agaaagagaa ccagagatcc
      601 aaccagcaga agtgaagcag gagcataaaa atactgtaga aacggcagaa caaaagaata
      661 ttgttcctgt tggttcactt tggatcgaca agaaagacgg gaaagtaatg gaagaagata
      721 cgggtcgaac gttacatttg aaggatgcgg cgtttattga agatccacag cataatcaag
      781 taattttaaa aggaaaaagt tatggaaaag agatccaaac ggcgttacct tcagaagaat
      841 ttgcgctagg aaattcattc cgattttcac ttgagacagt gtcagaagtg gcaaaacgaa
      901 aaaatgaaat ctattatgaa caacaattgt cacaaaaaga acgtgtataa aacaagtaaa
      961 aaagactatc tgaaaaacgg atagtctttt ttcttttggg aggttttaaa atgaccgaga
     1021 aaaaaatgag tcttattgat cgatgtaaac agatcgatat agtggatttt gctcgaaaca
     1081 atggaatggc tgtagtcaat aaaggacgag actatcgctt agaagaccat gattcatttg
     1141 tttttgatcg aagaaaacaa cgtttttatt ggaacagtca aaatattagt ggcgacatta
     1201 ttgaattagc taaacttttt ttcatagaca aagagatcca agaccctaag caacaattta
     1261 aagcagccac tgattttatt ctaaagaatg aagacaaaac agaacgagtg gaaaatcttc
     1321 attttgagac agaaaagtac aaagatcacc ccgttgatta tcaaccactc acagaaaaag
     1381 gaaggaatta tctgaaggaa gaacgaaaac taccagagtg gctgattgat tatgcagaaa
     1441 aagaagggtt gattgctgaa ctaaagccga aacatgaacg gcaaaatttt ttagttggag
     1501 acgaccgttt agatcatgcg gttgcttttt tatggaaaga tccacagaca ggagagacag
     1561 taggggcaag ttatcaagga acgatcgtcg attttaatcg tttcggtaaa cggggaacgt
     1621 ataaacacat tgacaagaat cctacgccaa atcacggatt taatttaaaa ataggcgatc
     1681 cgaagcattt aaaattcttt gaaagtagta ttgatctgtt aagttacgct gcattgaatc
     1741 gggagaaact acaagatgcc tggttagttt cgatggacgg gttaaaacat catgtaatca
     1801 gtcattacgt tgaagagtcg atttctgaat taagacgaaa acaaacattt cctcaatcga
     1861 ttgaaatatg tgtggacaat gatcgtgcag gacatatttt ttatgaaaaa gaacagatga
     1921 agggaatcgt tgatcctttt accaataaga aaatccgttg tgagcgagga attccaaatg
     1981 attggcaagt acctaaagaa tacaaagcta cttatgaagc agtcgcaaaa gaaatgagtg
     2041 ttgaacctga agcaattatg gccatacaca aaactgaaac taatttacag ctgacaaatc
     2101 aattggtgtc tgctcatgat gttcaatcta cgtttggaaa gatgttggcg aagggcgaac
     2161 cagtagaaac aattgatttg aaagaagcat gtaccacggt cgcgaaggaa ctgaaagtat
     2221 gtgaacgcgc agatggaaca tacaactttg atcgttttta tagtagaaaa gccaacataa
     2281 aagacgttaa tgcaggaatc cttctttcct ataaagcaga acaatactac aaaggctata
     2341 aaaagcatga acatgaattt gtacctgaag tgaaaaagga ttggaatgat caattgaagc
     2401 atgagatcca gcaacaagaa atcagaaagc aaaaacgtgc gatgttgttt caacaaggca
     2461 gacaacaaga aagggagtga agtcgtcact atgaaaaccg tcattttagc agaaaaaccg
     2521 tcacaagcga aggcttatgc cgatagcttt tctaaagcta cccgaaaaga tgggtatttt
     2581 gagatccaag atcgattgtt tacaggagaa actgtgatca cgtatggttt tggtcattta
     2641 gtcgagttag attcgcccga tatgtacgat gaaaaatgga aacaatgggc attagaacat
     2701 ttgcctattt tccccaatca ataccactat catgttccta aagataagaa aaagcagttt
     2761 agtgtcgtca aacgacagct gcagtcagct gatacgattg tgatcgcgac tgatagcgat
     2821 cgtgaagggg agctgattgc ctggtcaatc attcaacaag caggcgccaa tcaaggaaaa
     2881 acctttaaaa gactttggat caactcctta gaaaaagaag ccatttatca gggattccaa
     2941 cagttacgag acgcagaaga gacctatcca aaatttgaag aagtacaagc acgtcagatc
     3001 gccgattggt taattgggat gaacggtagc ccactgtata gtttactctt gcagcaaaaa
     3061 ggcataccag gaagtttttc tttaggtaga gtccaaaccc caacactcta tatgatttat
     3121 caattgcagg aaaagattag aaacttccaa aaagaaccat attttgaagg aaaagcccaa
     3181 gtaatcgctc aaaatggcgc atttgatgcg aagcttgatc caaatgaaac ccaagcgaca
     3241 caagaagcat ttgaagccta tttaaaagaa aaaggtgttc aattaggaaa acagccaggt
     3301 acgatccttc aagtcgaaac agagaaaaaa agtgcggcta gcccacgtct tttttcttta
     3361 tcgagccttc agtctaaaat gaatcaactc atgaaagcta gtgccaaaga tactttggaa
     3421 gccatgcaag ggttgtatga aggaaaatat ctaagctatc cgcgaacgga taccccttat
     3481 attacggaag gggaatatgc gtatctgttg gatcacttag acgaatacaa gcatttttta
     3541 aaagccgaag cgattccgac tcctattcat acaccgaata gtcggtatgt gaataataag
     3601 aaagtccagg aacattacgc gatcattcct acaaaaacgg ttatgacagc agcggctttt
     3661 gaacaactaa gtccactgca gcaggctatt tatgaacaag tgttaaaaac aacggtggcc
     3721 atgtttgcgg aaaagtatac ctatgaagaa acaacgatct tgacgcaagt tcagcagctt
     3781 cagttaaagg caatcgaaaa ggtgccgcta gatctaggtt ggaagaagtt atttggaaaa
     3841 gagagcgacg gaaaagagaa ggaagaagag ccgctacttc ctaaagtgac aaaaggagaa
     3901 atggtgacgg tggatctaca agttcttgaa aaagaaacca agccaccaca accttatacc
     3961 gaaggtacgt tgatcactgc aatgaaaaca gctgggaaaa ccgtggatag tgaagaagcg
     4021 caatccatat tgaaagaagt ggaaggaatc ggtacagaag cgacacgggc gaatattatt
     4081 gaaaccttga aacaaaagga atatatcaag gtagagaaaa ataagctcgt ggtgacgaat
     4141 aaagggattt tgctttgcca agccgtggaa aaagagccgc tgcttacgag cgccgaaatg
     4201 accgccaaat gggaaagcta cttgttaaag atcggtgaac gaaaaggaac acaaaccact
     4261 tttctagcca atatccaaaa atttgtctct cacttattgg aagtcgtacc agggcaaatc
     4321 caatccactg attttggatc gacgttacaa gaagtgaaag cagccagtga aaagcaagaa
     4381 gccgcgcgtc atttaggaat ttgtccaaaa tgccaggaac aagaagtctt actctatcaa
     4441 aaggtggcag cttgtacgtc tgaagcctgt gattttaaaa ggtcagaagg gttcatttga
     4501 agcaacgatt gttttaaaag aagacttcac tacaggcttt gaattttctg aaaagaaaaa
     4561 aacgaacttc aagaaaagaa cacgccgcac tgcaaaataa tggagggtta atcttatgcg
     4621 taataccaca cacaaacaac aagaaatcga aaatcaaaaa gccaaaattc gttcagaaca
     4681 ggaaaaaatg cgtgccagca aacgaagact gcagcaattg aagaaccagc agaggattca
     4741 aaaagaaatc gaattagatc gataaaatct tcctaactat tgtatacgta taaacttatg
     4801 ttatactgtt tttataagtt tatacgtata caaaggaggg agaaaatgac aaaagcaatg
     4861 gtatacaagc tgctagaaga atttaatgga actttggctt tgaaggatgc caaaaaagcg
     4921 ggcatttctc ctgtaacgat caaacgtatg gtagatcgag gggagctgga tcgagagtat
     4981 ccaggttttt tcaccttacc tggtcaattt cctgatgaat tgtttatggc gcaaaaaaaa
     5041 tatgaacgcg gcattatttc acatattacc gcgttagatt tgtatgattt aacagatatg
     5101 atccctagac agatcgatct gactgtacct tacggttatc acgtttctga aaaaggattg
     5161 aaggaattcg cagttgagct acactataca aaagcggaat ggtatgaatt aggtaagatt
     5221 gaaataaaaa gtcgctatgg gaatcctatt atagcttatg atccagaaag aactttatgt
     5281 gacatttgga atccctggta taccgttgag gatgaaatca aagtaaaagc aatcaaaaac
     5341 tatatggagt cggacagaaa aaatcttaga aaattgaatg agtatcgacg aattttacca
     5401 acagacaaaa cgatgcgttc ttatattatg gctttaaatt aaaggagaag atacatgaca
     5461 cctacgcagt taaaagcaaa agtgaagaat atttctagag aaaaagaagt tgatccgcag
     5521 cttgttttaa gacattttat gatggaaaaa ttcttggaaa aaatctcaga gtctccttat
     5581 cgtgaaaatt ttgtgttaaa aggcggcttc ttgattggct caaagtatgg cattgaaaat
     5641 cgcacaacca aagatattga tacgacttta cgggaaatga aagtaaccaa agaaacatta
     5701 acaacggttc taaacgaaat tttttcaacg ccgacgaaag aaggcattca atttgagatt
     5761 caaggaatga aagaaacgag agaagccgat tactatccag gatttagctt acgtgtgctg
     5821 gcacatttgg aaaacatgcg gccagatttt aaggtagatg tgactacagg tgactcgatc
     5881 tatcctgcaa cgatcactca cagtcataaa ttgatgtttg aggatcgaac gattcctttg
     5941 gaatcctatc ctacagaaca aattattgct gaaaaattaa gtgcaacctt tgatttttta
     6001 acagataatt cgagaggaaa agatttttat gatctctata ctattcctaa aatggagaag
     6061 atcgatgaga agaccttgaa agatagtgtg agaaatacat ttacacgtcg aggaaaaact
     6121 gatccgttaa agatatacta tgaaaaggat atggatgtac tgaaaaatag tcacgagcta
     6181 aaagatacct ggaagaaata tcaaaaaagc aatccttatg ctgcgtcgat cacgtacgat
     6241 gagacaatgg attcgattag taatttgatg gaaaaagtga ttcacgtcga agaaaaagag
     6301 cgaaaactag cttatcaaag acaccaacag atgaatagag aaatggagag ataaagatga
     6361 ttaataatgt gacattagta ggacgcttaa ccaaagatcc tgatttacgt tataccgcaa
     6421 gtggtactgc agtagcgact tttaccctag ccgtcaaccg aaatttcacg aatcaaaacg
     6481 gcaattgaga agccgatttt attaactgcg tgatttggcg caaaccagca gaaacaatgg
     6541 cgacattagc taaaaaaggt agcttgattg gtgtagttgg gcggattcaa acgcggactt
     6601 acgacaacca gcaaggacaa cgtgtatatg tgactgaagt tgtagcagat aactttcaac
     6661 tattagaaag taaagcagcg acagagagcc gtgcgcacgc tgatcaatcg tccaccagtc
     6721 caagcaccgc cacctttgaa caacggaata cagcgacgcc taacaacaat ggattgaacg
     6781 cttcacagaa tccatttggt ggacaatcaa tcgatattag cgatgatgat ctaccgtttt
     6841 agtttgagaa agaaggagta agcatggcaa aaaaaattag tctgacgatg gatctattga
     6901 tacccgtaat tgcatttata gacgggattt ctttgggcgt cactgaaaat cctttggtaa
     6961 atagaattgc gaaaggatca ctatttcttg tattcgtgta tcttgtctgt tcttatcttt
     7021 taaaaagagc aggaaaggat aattcctttt ggcgattgac taaagtcaca gtagcagcga
     7081 cagctgttat acttacggct attctaccgc tttatatgta gagttaacgg gaaatcgttg
     7141 aacttcttgc gaaatattgc tataatgaac atgaaaaaga ggagttgcgc taacaacccc
     7201 tcattaacag caccgattaa agaacggtgg cagaatatta gttatttgga aataaccgct
     7261 gacctgctaa agtagacggt tatttctttt tgtcattttt aagcatattt acaatcaaac
     7321 taatcaaagc aatggtaaac ataccaaaac caagaatggt ttgaattgtc tcatatgcgg
     7381 acaaaaggct tactcctttc atagatttta gcacttacat tcataagcac caccaccttt
     7441 ccagaagtcg ccaccgtctt caaactttac tgtcttgact attatagcat atctaaaatc
     7501 gaataaaaat tctcaatttt agctgttttt gctataattt tagcgaggtg atcgtgatgg
     7561 aacaatatat tggtttactc gataaattag ggtgatcaag acacagccat tgcttgtgcg
     7621 atttacatta cgcacgagtc atgaaccaat caattgtgta gtggccaata tagaaatagc
     7681 ggataaattg ctgattttgg aagaaggcaa gtatactatt tcagtgacag gtcacttcaa
     7741 taaacgaaat caactagtca ttgaatcaat gcaaattaga aaccctgatc attttacgag
     7801 attaatgggc atataaataa aagaagagct gcagtcctaa atgaggattg cagctctttt
     7861 tgttttacat agaaacaaga aaaatgaaaa ggccttttta ggaaggcgca agcgccttct
     7921 caattgaaaa acctctctct cactccaacc gccaccgccg ttcgagaaga aaggaagtga
     7981 acgttgcacg ttcactaaga taaggggtct tgcaaagcaa gacaaaatag aaaaaacttc
     8041 ctctcaccaa aaggttcgtt cctgttcgct atctctttat tgatttgcca gaccggcaac
     8101 aagttgcctt ttatcaccaa aaagcgacaa ggacaagggt aaatggcacg ctgcacgccc
     8161 ttgtccttgt cgcttttagt tgattcattc tggccaacaa atcaataaag aaagaactaa
     8221 cgaaaggaag taaaaccttt cctaagagga ggcagaatca atcatgcgaa agaaatttga
     8281 ttattggggt gttcccttca gcgaattatt cccaaactat catgcaccat atactgtcga
     8341 atgcgattgt ggagaaagag cgaaatgtat caaaagctat tgtttgtatc aatgtccaac
     8401 atgcgggaaa aaatatacct tgtcttatgg cgatta
//
LOCUS       DAFELK010000084         8293 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFELK010000084
VERSION     DAFELK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.088"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            433..600
                     /locus_tag="LP433_002636"
     CDS             433..600
                     /locus_tag="LP433_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2006751.1"
                     /translation="MVYLNKKQTCEFLGIDNNTLDKWIRIYNFPVIKIDGIIRFDVED
                     IKGFMDTFKKI"
     gene            674..1900
                     /locus_tag="LP433_002637"
     CDS             674..1900
                     /locus_tag="LP433_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2006752.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFKEITGISSEKFQKTFPTRQLAIKA
                     ENEMKKKIAKVLREENANSLELKGQIKFKEFYKSKWLPRYELGQTTRSHKAPSDITII
                     NTKNLFRLHILPIFGEYAMSYLNANTEIISDELTKKSKEYANIKIIKCYVRSMFDIAE
                     VLNYIEFNRTTKIIQSITAPKKVALEEKRIREGKQALSSKELTDWLDAVRDDFNDQLL
                     SFHDYTLFMLTLYLGDRKSETYALQWKYIDFENQTVRLKYALDKHTKKKFTKGRKDTI
                     IQVPEIVMTLLQEWKSVQAEQLLKLKIKQTPDQYLFSYSKPSGEVNCPVHTDYLNYRI
                     NSIKKRHPHLVHLTPHKLRHTYATLARQGGADMNQISNALTHSGISTTKIYVNTPDLV
                     DKAVFEAFQRGLQKSN"
     gene            complement(2058..2675)
                     /locus_tag="LP433_002638"
     CDS             complement(2058..2675)
                     /locus_tag="LP433_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006753.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTLKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
     gene            complement(3358..4353)
                     /locus_tag="LP433_002639"
     CDS             complement(3358..4353)
                     /locus_tag="LP433_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2006754.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
     gene            complement(4448..5320)
                     /locus_tag="LP433_002640"
     CDS             complement(4448..5320)
                     /locus_tag="LP433_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2006755.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            complement(5333..6760)
                     /locus_tag="LP433_002641"
     CDS             complement(5333..6760)
                     /locus_tag="LP433_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBL2006756.1"
                     /translation="MTKKAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEIKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            complement(6814..8088)
                     /locus_tag="LP433_002642"
     CDS             complement(6814..8088)
                     /locus_tag="LP433_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2006757.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
BASE COUNT         2747 a         1522 c         1185 g         2839 t
ORIGIN      
        1 attttaaatt tttacatacc tgtttatgaa aaactaaata atctgtcaaa aaaatatgat
       61 tgttcatttc taaatatgtt ttccaatttt aaaatctttt ttagcatttt tgtttccttt
      121 tcatatggtt tttcgttgtt aatagtgact aggatgatat tcctattttg accattgaca
      181 attaaatata atttttgaat aacgttccct gctattcgag ctaagaattc aagtacgcca
      241 tgacctattt agcgataact acttagagat ttctttttgt tttgggaaga caaaatgcca
      301 tgacaatagc agtagataat gatacttccg taaggctcgc cgtaaactgg ggagaggtga
      361 aattcctatg tgcttaccca agtcaattca aaaattttag ttcatttata aggggatgat
      421 tttattaaat caatagtcta tctaaacaaa aaacaaacct gtgagttttt aggaattgat
      481 aacaatactt tagataaatg gattcgtata tataattttc ccgtaataaa aatagacggt
      541 ataattcgct ttgatgtaga agatatcaaa ggctttatgg atacgttcaa aaagatttga
      601 attttacttt tgactgcata tactaaaagt agcgaaatat actgccttac ttttttatta
      661 aggagtgagg aagttgccta cgaagctttc aaatggaaaa tataaaacta atttgagata
      721 tccaaaaaaa tttaaagaaa ttacaggtat cagttcagaa aaattccaaa aaacatttcc
      781 aactaggcaa ttggctatta aagccgaaaa tgaaatgaaa aagaaaatcg caaaagtctt
      841 aagagaggag aatgcaaatt cattagagct caaaggtcaa ataaaattca aggagtttta
      901 taaatctaaa tggcttccta gatatgagtt agggcaaact actagatccc ataaagctcc
      961 aagcgatata accatcatta atacaaagaa tttatttcga ttgcatattc tgcctatatt
     1021 tggtgagtat gccatgagct atcttaatgc aaataccgaa ataatatcag atgaactcac
     1081 aaaaaagtcg aaggaatatg caaacataaa aatcattaaa tgctatgttc gttccatgtt
     1141 tgatattgca gaggttctaa attatattga atttaatcgt acaacaaaaa taattcaaag
     1201 tattactgca cctaagaaag ttgctctgga agaaaaaaga atacgagaag gaaaacaagc
     1261 tttatcttcg aaagaactca ctgattggtt agacgctgta agagatgatt tcaatgatca
     1321 attactttcc tttcacgatt acactctttt tatgcttact ttatatcttg gggatagaaa
     1381 gagtgagacc tatgctttgc aatggaaata cattgatttt gaaaaccaaa cagtccgtct
     1441 taaatatgcc ttggataaac acacaaaaaa gaaatttaca aaaggtcgaa aagatactat
     1501 tatccaagtt ccggaaattg taatgacact attgcaagaa tggaaatcag tgcaagctga
     1561 acaactattg aagttgaaaa ttaaacagac acctgaccaa tatcttttta gttactccaa
     1621 accttctggt gaagtaaatt gtccagtcca tactgattac ttaaattatc gaattaattc
     1681 tataaaaaaa agacatcccc atttggttca tttaactcct cataaacttc gacatactta
     1741 cgcaacttta gctagacaag gtggggctga tatgaatcaa atttctaacg ctttgacaca
     1801 ttcaggtatt tcaactacaa aaatttatgt gaatacacct gatttagttg ataaagctgt
     1861 gttcgaagcg tttcagcgag gattacaaaa atctaattaa tgtgttctag aatgtgttct
     1921 aaatataaaa aaaagacact ttccaaataa ttggaaagcg tcttgaacgt tgatatataa
     1981 aggatattaa cgttttgaga attgagatgc tttacgagct ttcttaagac ctggtttctt
     2041 gcaaaattat attagcctca actgaaagat ttattttttt gctccctaac ttcattagta
     2101 ataccatgtt tcattcgata tcttctaaac gttctacgat taatccctgt tagctcttca
     2161 acttctttat ctgtagatcc agtcaaaaac aaattaaatg ctaattgaag tcgcggatca
     2221 ttctcacgat attttagcgt acctcccttg tatttccctt ttgctttagc gagtgcaatt
     2281 ccttgttgtt gcgtttcgcg aatataccga cgttcttctt cggcctggta cttgtatagt
     2341 tcgataatta agttattaag taatcgacgt aaattatcat cagtgatacc tgttaacgct
     2401 ggcaaattca aaacttccag tgtagctttc ttcagctgaa ttaaattcat cgtttctgtt
     2461 agctctttat tatttcgtcc aagtcgtttt aattctgtca caacgacaat atcaccttca
     2521 cgtatgaatt tcatcatttc ttgaaatcct tctcgattgg tatctttccc acttgcttta
     2581 tcactaaaaa ttttatcaca ctctgataat aattctaatt gtcggtctaa attttgatct
     2641 aagctgctta ctcgagcata cccaattttc gccataataa aactccttta aaattctgaa
     2701 atccggatca tttttaaatt ctgttgccca actctgttgt catttttcta gataaatggc
     2761 ataaattttc agcgctaagt gacaaaagca actaattttt catgatagat ttttaaatat
     2821 ctcaatctat ctccaaaatt agttgctttt gtagctatag ttgactatga atatgacaaa
     2881 taattagaaa aaactgtgcc aattaaatat aaaaatgaca ctcatttaca ttcaatagaa
     2941 caccaagagc ccaacagggt atactctggt gtccttttaa aaaagtaact ttctgaccta
     3001 attaattgag ctactaaaaa agctatgaaa tgaggaataa aaaagggatc aaaaactttt
     3061 aagtttctga cccttttgag ttctaattat ttcttccaga acgaagaatg ttatctgctt
     3121 tatctgcaat tgattctgtt agaaggactg aaaaatttat gccagccctt ttgcctagct
     3181 tatccgccca ttgaggaatt gttaaggttt ttctgacaag ttctatgtct ttcaaatatt
     3241 tggcaacatc tacacagatt aaaagcatga ttttgtatca tagtctatta taagagattt
     3301 aacaattttt tatatcacga attaataatg aaattatcat tgatagtctt tataaattta
     3361 attgttcttt ttctttactg atgtcttccc catccataat gtgacaggta aaatatattc
     3421 cttttttgtt tcttctttat ttattcgttt catcaaaata gcaacagctg tgtctgctat
     3481 atcattaatt ggttgtatta ctgttgtcag atctggtaat atactccgag tcattaaagt
     3541 accatcatat ccgactacta ataaatcagc tggtacattt aacccctttt cttttgctac
     3601 ttgtaatatt agggccgcat cgatgtcatt tgaagcaaaa ataccatcta ttttaggata
     3661 atcctcaaac atttggaaaa aaatctgttt tttctttaca taagaaatat tgaaatctaa
     3721 tgtcacagtt cgtggaatta actgatatgc tttcatagta tcttcatagg ctagtctccg
     3781 acgattagcc ggagtctgta agtcaattgg accgtttgta tgaataatat tttttgcacc
     3841 ttgtgcaatt aataacttgg ttgcaagttt tccaccattg tagttatcgg attcaacaac
     3901 tggaatatct tcattcatca ctcgatcaat tgcaacaatc ggtaaattct gatatttata
     3961 ttcctgaatt ccttggttat gtgtaccaac aattaaacca tctacttgat cagacaataa
     4021 ctgatttaaa taatttgttt ccttttcttt attattcatc gaattgccta ttaatacctt
     4081 ataaccaatt tcatataact ttttttccaa tgcctcaacg agttcactaa aaaaaggatt
     4141 ggctactgta ggaaatagta acccgacaat gttagttttc ttttgaaata attgacgcgc
     4201 tacaacgttc ggttgataat tgagttcttc tatagcctta taaacattat caatcgtttt
     4261 ttgacttaaa tagccacgat tgtttaatac acgtgaaaca gttgtttttg atacatttgc
     4321 tcttttggca acatcttcta attttgggcg cattctcttg tctctcctaa ataatgcaat
     4381 aattaactat cgaaaaaaag aactctatag aactactata cctgataatc gatatttttt
     4441 ctatgtttta ttcttgtaat tgattcaagc ccaaagcaaa gtttcctagt gttgccgatc
     4501 cattattttt aattaaagga cgcgtaatat atttacttaa cggtggtatt tccacgtaat
     4561 catccaataa tttattaaca ttaacacgaa ttttttctaa caatttttca tttactacgc
     4621 ttccaccaaa tactatttta tccggtcgta taatcaatgt tgtttgaatc acagcttgtg
     4681 ctagataata ggccattaca tcccaaatag gatccgttaa agaaacgtct tcaccctttt
     4741 ttccaaaacg tgcttcaaac gttggtcccg caactaagcc ttctaaacaa tcaccatgat
     4801 aaggacaaat tcctttaaaa tcaatatcat caggatggcg ttttacaaac gtatggccca
     4861 tttctgaatg accaaacgat cctaatagtt ttccgtcaac aacagctcca ccaccaacgc
     4921 cagtaccaac ggtgtaataa actaatgaat ttattttttc attcgataaa gtggacatga
     4981 tgtactctcc ataagctgat ccgttcacat ccgttgtcca agacattgga acattcagct
     5041 catcttgtaa ataacctaac acattaacat ttcgccatcc cacctttggt gtagacgtaa
     5101 tatatcctga ttttggtgaa ttttttcgaa tttctattgg accaaatgat gcaataccta
     5161 atgcatttat atcaaactgt ttaaaatagt caacagtttt tttcaatgtt tccctggggg
     5221 tggtcgttgg acaaattatt tggtcttgta ctcggtaatc ctcgtctccc acggcacata
     5281 caaatttagt cccacctgct tctatgctac caattaacat cataaaacct ccttactcgt
     5341 aagaaattgc atcttttttt agatgataaa ttgtactcga gacaaaagct tcttcactaa
     5401 cactcaaatg catacttggt tgattttctg tataataacg ctctgtaaaa acaagctcgc
     5461 catcattaat aaaaatctct gccgaacttt tatcgataaa cactcgaagt gataatctat
     5521 cacacatctg aatggttcca taccttggat catttttgcc gttacgagtt aaggtacatt
     5581 catttttatc cttagaataa aaaatattga ttaactcttc atcttttgtt tttaatgaaa
     5641 atttgatttc ttgatttttt gatttagtca atagtacatc aattagagct tctttgaatg
     5701 aagcatcttg agcgattatt atttctcctg ccaaattaac tgtcgtttca acgccgctgc
     5761 caactcgaag ttgttctaat tctctcacag gtttcatata caaacgatct ccaattaact
     5821 ctaattctcg aggaagcgtt aatgctcctg cccatccgtc tactttttca ggcatagggc
     5881 tttcccacat atccatccag gccataacaa tacgtctacc atctggagat aaagttgttt
     5941 gtgttgcata gaaatcgtgt cccttatcta attcataaaa atttcctcta atgaattttg
     6001 ctgtctcata atcataatca ccgataaagt agcctgtttc atatagattt aaataatctt
     6061 ttccatttgc ttcaattccc tgaggggata ataaaagaat agattttcca tttaattcaa
     6121 aaaagtctgg gcattcccac ataaatcctt ctgtaagtac ttccttcgct ttagaaattg
     6181 gtccaatgta atcccaattt aataaatcta acgactgata aacaatagca cgacctaatc
     6241 catctttttc ttgactaccc aaaaccatgt aatatttttc atcgtgtttc catacttttg
     6301 gatctctgaa atgatgtgtg ttatcttctg gtgcttttgc tattacagga tttttttcat
     6361 atttagtaaa gtgaatgcca tccgtactat acgccatgtt ttgattttgc caaaaatgat
     6421 ctggatcatt gtctccataa tagtgatgtc ctgtatagaa cagatacaac acaccatttt
     6481 tttcaatagc gcttcctgaa aaacaaccac cttcatcttc ttgatctcca ggagtcaaag
     6541 caagtggtaa agattcccaa tgaactaaat ccttacttct agcatgtgcc cagtgcattg
     6601 gtccccattc agcactatat ggatgatgtt gataaaacac atgataatac ccatcaaaat
     6661 agcaaaatcc atttggatca ttaatccatc ctgatggtgc agacacatga tatcccaaac
     6721 gataacgtgt atttgttaat tctatagctt tttttgtcat aatatattcg ctcactttct
     6781 agataaaatt gttttttatt ctgttggttt ccattatcct cgaataaatg gatccccttg
     6841 aacatctcta tcatcttgtt taagaataaa gaatgcatat atgcctgcta gtaatacaat
     6901 aagagaaata attttaaatg ttggttgata gccaacgttg tctcttaata ttcccaatgg
     6961 tgttgataaa atcacttgcc caatttgagc agctatctga aatcctatca tatagagggt
     7021 tgctgatagc tttgtatcaa aatgaagtgt aaaatagcga aacattggta atgtaaataa
     7081 tggtacttct aaagcatgca acatttttat gcatgaaaca gataatggtg tcgaggcaaa
     7141 cccgcacaat ccaattcgta cacacataat ggttacacct aataacaaag tatttcgaac
     7201 ccctaatttt ctcataatga ttggaacaat tcccatcatt aacgcttcac aaaatacttg
     7261 aatagcattc aatgtcccat atattttttc accattagct gatgttgaaa acaaaccagt
     7321 ataaaatccc ggaaacattt gttgatcgaa taccgtataa aatgtccatg taaaaacaat
     7381 aaagatgatt atcgtccata attgaggcag tttcattaga tcaaacattt cttttaaaga
     7441 aggaatacta tttgattcag cttgttcttg attaaaattt tgatttgctt cccgttcaac
     7501 tttagggttc caaaataata aatttaacaa tagtaaagaa ccaaagaaag atcccgccca
     7561 aaagtttaaa tgaggatttt ttacaaataa aaatcctgcc aaaagcgcta ccaaggcata
     7621 accaaatgat ccccacgccc ttgcttgtcc atattcaaag ccaaataaac gactaaacct
     7681 ttctgacaca gcttcaaaaa ctcctacaga agctaaatat ccagctgaca aaaatagcgc
     7741 tcccataata atgcctaaat taaaattgtt atctagcaat ggcccatata tccatataaa
     7801 aaatggtcca acaagtgtcg ctaatacaga agcaaaaatt aataaatttc gtttaatata
     7861 caatttatct tgtaatgttc cataaataaa catcaaaatt aaggtaacta acgaatttgc
     7921 cgagaatact gttcctacag cactgccaga taaccctaaa ccatttgatt cagatgttag
     7981 ccaaagttga aaaaatgacc accaaacacc ccaagaagca aaaaatagta ataatgtagc
     8041 tgaactttgt aaataagatt gatttttaaa tacgttaact tttgacatat ttttatcctc
     8101 caacgatata tttgtatccc ctttcatgat aaccggttaa catttttaga aaaggacttg
     8161 tactcctaaa attataaaag aaatccgctt acatgtcaac cggttattct atttggataa
     8221 tgccatataa tgtcacagga tatgactttt attggtgtgt cgcttttctt ttttaatggc
     8281 actatttttt ata
//
LOCUS       DAFELK010000085         8229 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFELK010000085
VERSION     DAFELK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.089"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="LP433_002643"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="LP433_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBL2006758.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="LP433_002644"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="LP433_002644"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBL2006759.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="LP433_002645"
     CDS             2591..3376
                     /locus_tag="LP433_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2006760.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="LP433_002646"
     CDS             3389..4240
                     /locus_tag="LP433_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBL2006761.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="LP433_002647"
     CDS             complement(4364..4816)
                     /locus_tag="LP433_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2006762.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="LP433_002648"
     CDS             complement(5281..5649)
                     /locus_tag="LP433_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBL2006763.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="LP433_002649"
     CDS             5799..6281
                     /locus_tag="LP433_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBL2006764.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="LP433_002650"
     CDS             6318..7328
                     /locus_tag="LP433_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBL2006765.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="LP433_002651"
     CDS             complement(7443..8156)
                     /locus_tag="LP433_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006766.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2441 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtct
//
LOCUS       DAFELK010000086         8160 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFELK010000086
VERSION     DAFELK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.090"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..950
                     /locus_tag="LP433_002652"
     CDS             <1..950
                     /locus_tag="LP433_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006767.1"
                     /translation="YYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQLDKKGQSELQAG
                     IQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNTRNTPTQHLATS
                     IHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYIAAWTKNGQTLD
                     DKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQEHKNTVETAENK
                     NIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGKSYGKEIQTALP
                     SEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            1011..2471
                     /locus_tag="LP433_002653"
     CDS             1011..2471
                     /locus_tag="LP433_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL2006768.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2482..4686
                     /gene="topB"
                     /locus_tag="LP433_002654"
     CDS             2482..4686
                     /gene="topB"
                     /locus_tag="LP433_002654"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL2006769.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAESIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            4702..4851
                     /locus_tag="LP433_002655"
     CDS             4702..4851
                     /locus_tag="LP433_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006770.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4925..5518
                     /locus_tag="LP433_002656"
     CDS             4925..5518
                     /locus_tag="LP433_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL2006771.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            5534..6433
                     /locus_tag="LP433_002657"
     CDS             5534..6433
                     /locus_tag="LP433_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL2006772.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            6436..6921
                     /gene="ssb"
                     /locus_tag="LP433_002658"
     CDS             6436..6921
                     /gene="ssb"
                     /locus_tag="LP433_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2006773.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            7287..7547
                     /locus_tag="LP433_002659"
     CDS             7287..7547
                     /locus_tag="LP433_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006774.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            7988..>8160
                     /locus_tag="LP433_002660"
     CDS             7988..>8160
                     /locus_tag="LP433_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL2006775.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGD"
BASE COUNT         2980 a         1418 c         1689 g         2073 t
ORIGIN      
        1 cttactacac gattgaaaaa gtgtttgata tcacacaaac acagttaaaa cctgaagact
       61 atccgaaaat ctttccgaac cgtgtctttg attttcaatt ggataaaaaa ggacagtcag
      121 aacttcaagc tgggattcaa gcggtagcca acaatattgg aatacaaatt cgagatatga
      181 cagaaagtga agtctatcaa agagaattag gacaagcacg tggggcgtat gttcgtaacg
      241 aatttactgg cgaagaagaa atcgtcatga atactcgaaa tactcctacg cagcatttag
      301 ctacaagtat tcatgaatta gcccatgcaa gaatgcacaa attttcagaa ttagataccg
      361 caactaaaga attgcaggca gaaatgactt cttatattgt gtgcaaacat tttggaatgg
      421 acacgtcgga gaaagctatt ccttatattg cagcatggac gaagaatggt cagacgttgg
      481 atgataagga agcggcggaa cgtgggaaaa tcatgaatga tgtcagccgt gtcgcaaatg
      541 aattcattca aaccatttct aatgaaatca atcaatacag agaaagagaa ccagagatcc
      601 aaccagcaga agtgaagcag gagcataaaa atactgtaga aacggcagag aataagaata
      661 ttgtgcccgt tggttcactt tggatcgaca agaaagacgg gaaagtaatg gaagaagata
      721 cgggtcgaac gttacatttg aaggatgcgg cgtttattga agatccgcag cataatcaag
      781 tgattttaaa aggaaaaagt tatggaaaag agattcaaac ggcgttacct tcagaagaat
      841 ttgcgctagg aaatccattc cgattttcac ttgaaacagt gtcagaagtg gccaaacgaa
      901 aaaatgaaat ctattatgaa caacaattgt cacaaaaaga acgcgtataa aacaagtaaa
      961 aaagactatc tgaaaaacgg atagtctttt ttcttttggg aggtttgaaa atgaccgaaa
     1021 aaaaaatgag tcttattgat cgatgtaaac agatcgatat agtggatttt gctcgaaaca
     1081 atggaatggc tgtagtcaat aaaggacgag actatcgctt agaagaccat gattcatttg
     1141 tttttgatcg aagaaaacaa cgtttttatt ggaacagtca aaatattagt ggcgacatta
     1201 ttgaattagc taaacttttt ttcatagaca aagagatcca agactctaag caacaattta
     1261 aagcagccac tgattttatt ctaaagaatg aagacaaaac agaacgagtg gaaaatcttc
     1321 attttgaaac agaaaagtac aaagatcacc ccgttgatta tcaaccactc acagaaaaag
     1381 gaaggaatta tctgaaggaa gaacgaaaac taccagagtg gctgattgat tatgcagaaa
     1441 aagaagggtt gattgccgaa ctaaagccaa aatatgaacg gcaaaatttc ttagttcgag
     1501 acgatcgttt agatcatgcg gtcgcctttt tatggaaaga tccacagaca aaagagacag
     1561 taggggcgag ttatcaagga acgttcattg attatgaacg ttttggtgag agaggcacat
     1621 ataagcatat agataaaaat tcgacagcga atcatggctt taacctaaag atcggtgacc
     1681 ctaagcagtt aaaatttttt gagagtagta ttgatttact tagctatgct gcactgaatc
     1741 gtgatcagtt aaacgatacg tggttagtct ctatggaagg gttaaaacac catgtgatca
     1801 gtcattattt tggtgaggca gtatctgaat tgagaaagaa acaagccttt cctcaatcca
     1861 tcgagatttg tgtggataat gaccgtgcag gacatatttt ctacgaaaaa gaacaattaa
     1921 tgggcgcagt cgatccattt acgaatcaga aagtacgttg tgaacgagga atcgctaatg
     1981 attggcaagt gccaaaagaa tacaaaatca tttatgaaga agtcgcaaaa gaagaaaagg
     2041 tcacaccaga agctattatg gccatacaca agacagaaaa caatctgcaa ttaacgaacc
     2101 aactggtttc cgctcacaaa gtaaatgcgt tttttggcca gcagctttct gttaacgatt
     2161 caatagaagc cattaatttg aaagatattt gtagagaagt cgcaaaagaa ttaaaagttt
     2221 gtgaacgcgt ggatggtacg tacgattttg atcgttttta tcaagaaaaa ggggatatta
     2281 atgcgcagat tcttttctct tataaagcag aacaatacta caaaggctat aaaaatcatg
     2341 aacatgaatt tatacctgaa gtaaaaaagg actggaacga tcaattgaag catgagatcc
     2401 agcaacaaga aatcagaaag caaaaacgtg ccatgttgtt tcaacaaggc agacaacaag
     2461 aaagggagtg aaatcgtcat gatgaaaacc gttattttag cagaaaagcc gtcacaagcg
     2521 aaagcttatg ccgatagctt ctctaaagcc actcgaaaag acgggtattt tgaaatccaa
     2581 gatcgattgt ttcctggtga aactgtgatc acgtatggtt ttggtcattt agtcgaatta
     2641 gattcgcccg atatgtacga tgaaaattgg aaacaatggt cattagaaca tttgcctatt
     2701 ttccctacac attatcacta tcatgttcct aaagataaga aaaagcaatt caaggtggtg
     2761 aaacagcaac ttcaatcggc cgacaccatt attattgcga cagatagcga tcgtgaaggg
     2821 gaactgatcg cttggacgat cattcaacaa gtaggcgccg atcaaggaaa aacctttaaa
     2881 agactttgga tcaactcctt agaaaaagaa gccatttatc agggattcca gcagttacga
     2941 gacgcaaaag agacctatcc aaaatttgaa gaagcacaag cacgtcagat cgccgattgg
     3001 ttaattggga tgaacggtag cccactgtat agtttactct tgcagcaaaa aggcatacca
     3061 ggaagctttt ccttaggcag agtccaaacc ccaacgcttt acatgattta tcaattgcag
     3121 gaaaagatta gaaatttcaa gaaagaacct tattttgaag gaaaatccga agtaatcgct
     3181 caaaatggcg catttgatgc gaagcttgat ccgaatgaaa cccaagcgac gcaagaagca
     3241 tttgaagatt atttaaaaga aaagggggtt caattgggaa aacagccagg catgattcgc
     3301 caagttgaaa ccgagaaaaa aagcgcggca agtccacgtc ttttttctct atccagcctt
     3361 cagtctaaaa tgaatcagct catgaaagct agtgccaaag acactttgga agccatgcaa
     3421 ggcttgtatg aagggaaata tctaagctat ccacgaacag acacccctta tattacggaa
     3481 ggggagtatg cgtatttgtt ggatcattta gatgaataca agcatttttt aaaggccgaa
     3541 tcaatcccaa cccctattca tacgccgaat agtcggtatg tgaataacaa gaaagtccag
     3601 gaacattacg cgatcattcc tacaaaaacg gttatgacag cagcggcttt tgaacaacta
     3661 agtccactgc agcaggccat ttatgaacaa gtgttaaaaa caacggtggc catgtttgcg
     3721 gaaaaatata cctatgaaga aacaacgatc ttgacgcaag tccagcagct tcagttaaag
     3781 gcaatcggaa aagtaccgat agatctaggt tggaagaagt tatttggcaa agagaacgac
     3841 ggaaaagaga aggaagaaga gccgctactt cctaaagtga caaaaggaga aatggtgacg
     3901 gtagatctac aagtccttga aaaagaaacc aagccaccac agccttatac cgaaggtacg
     3961 ttgatcacgg cgatgaaaac agctgggaaa accgttgata gtgaagaagc gcaatccata
     4021 ttgaaagaag tggaaggaat cggtacagaa gcgacacggg cgaatattat tgaaaccttg
     4081 aaacaaaagg aatatatcaa ggtagagaaa aataagctcg tggtgacgaa taaagggatt
     4141 ttgctttgcc aagccgtgga aaaagagccg ctgcttacga gtgccgaaat gaccgccaaa
     4201 tgggaaagct acttgttaaa gatcggtgaa cgaaaaggaa cacaaaccac ttttctagcc
     4261 aatatccaaa aatttgtctc tcacttattg gaagtcgtac cagggcaaat ccaatccact
     4321 gattttggat cgacgttaca agaagtgaaa gcagccagtg aaaagcaaga agccgcgcgt
     4381 catttaggaa tttgtccaaa atgccaggaa caagaagtct tactctatca aaaggtggca
     4441 gcatgtacgt ctgaagcctg tgatttcaaa ctatggacaa cgattgccaa aaagaaactt
     4501 acagcgacac agctgaaaga gatcattcaa aatagccgaa caagccaacc agtgaaaggg
     4561 ttaaaaggtc agaagggttc gtttgaagca acgattgttt taaaagaaga cttcactaca
     4621 ggctttgaat tttctgaaaa gaaaaaaacg aacttcaaga aaagaacacg acgcactaca
     4681 aaataatgga gggttaatct tatgcgtaat acaacacaca aacaacaaga aatcgaaaat
     4741 caaaaagcca aaattcgttc agaacaggaa aaaatgcgtg ccagcaaacg aagactgcag
     4801 caattgaaga accagcagcg gattcaaaaa gaaatcgaat tagatcgata aattcctttc
     4861 ttgttaatat aaaactaaca tgttatagtt gtgttagttt tatattaact ttaggggaag
     4921 agtaatgaaa gacaaaatcc aatgtatttt tgataaacat aatggcaacc tatccttgaa
     4981 ggatgctaga agtgaaggat tatcgcctat gacgttagat cgattagccg aaaaggataa
     5041 aatagaaaag gtagcaccag gtttctatac cttaaaggat gcgttcgtgg atgaattgta
     5101 tctcgctcag agtatctatt ccagagggat tttttctcat gagactgcgc tcgatctttt
     5161 tcaagtagga acatatatcc ctaaaaagat caatatgatg tttcctaaag gatacaatgt
     5221 atcaaaggag aaattagatc agtatgccat tcaaccgcat tacactaata aagaaaattt
     5281 tgacctggga gtcacagaaa cagaaagctt ttacggcaat aaaattttag tctatgattt
     5341 agagcgaacg ttatgtgaca tgtggaatcc aagatacaaa gcaagcgtag aggtaaaaca
     5401 agaagcatta aaagaatata tgacaagtac cagtagaaat acaaataagc taagaagata
     5461 catggatatt ttaaaatcac caaaagaaat gactttgtat atgttgccac tttattgaga
     5521 ggagtaaaga tgaatgacac cgacacaatt taaagagaaa acaagaaatt tcgcagcaga
     5581 gaaacattta aacccacaaa ttgtccaaag atattatatg atggaaaaat tattagaatg
     5641 tattgttgaa tcgccttatc atgatgattt tgtattaaaa gggggatttc tgattggatc
     5701 aaaatacggg ttagaaaacc gttcaaccgt tgatattgat acgacttatc gaaattcgaa
     5761 actaacaaaa gaaaagttag aaactgtttt ttctgaatta acagctaatc ctacaaaaga
     5821 tggaattcgt tttgaattaa agggattaac agagacgagg gaagccgatt attatccagg
     5881 ttttcaagca aagtttattg cttatcttga aaatgcacgt gtacctttta aattagatat
     5941 tacttcaggt gattctatta ttccagcagc attgatgtat gaacacaaat taatgtttga
     6001 agataaaacg attcatattc cagcttatcc tacggaacaa attctagctg aaaaattaca
     6061 tgccacgttt agttttggaa aagataattc gcgcatgaaa gatttttatg acctgtatat
     6121 gattccgaaa ttagaacgta tcgatgagaa aaatttgtat aagagtgttc aaggaacatt
     6181 caaggaaaga aataatcaat cggtgtttaa gcatttgtat gatcaggaaa tgcctcaatt
     6241 ggtgaaagat gagggcttga gagaaaagtg gaaaagatac caacaagaaa actattttgc
     6301 caaagacatt tctttcgaat ctacactaac ttccgttgat tccctgatgc aatcaattgt
     6361 agagcaagag aaggcagaac gaaaacaaaa ttttaagaga tcacaacaaa tgaatcaaga
     6421 aatggagaga taaagatgat caataatgta actttagtag ggcgattaac taaagatcca
     6481 gatttacgtt ataccgcaag tggcacagca gtggcgactt tttccctagc cgttaatcgt
     6541 aatttcacga atcaaaacgg caatcgagaa gctgatttta tcaattgcgt gatttggcgc
     6601 aaaccagcag aaacgatggc gacattagct aaaaaaggca gcttgatcgg cgttgtcgga
     6661 cgaattcaaa cacggactta tgacaaccag caaggacaac gtgtgtatgt gacagaagtt
     6721 gtggccgata acttccaact attagaaagt aaagcagcga cagaaagccg tatgcacgct
     6781 gatcaatcgt ccagcagtcc aagccctacc acctttgaac aacgggatac agcgacgcct
     6841 aacaacaatg gattgaacgc ttcacagaat ccatttggtg gacaatcaat cgatattagc
     6901 gatgatgatc taccgttcta agtagcattt tctattggtt gcatttgcta cggtttatgt
     6961 tataatttag acaacaaaaa gaattttcaa tctataacca aaaaccacta gctggcgggc
     7021 tagtggcttt cttttacgtt tctattataa gaattaacgg gtaggcttac tgtctttctt
     7081 ggcaaattta caatcaagcc atttgcagat atagtgcgcg gctacttctg ccatgattgc
     7141 aaaaacaaaa tcaaaaagaa ttttcaaacc tataacctcc tccccttgcc agattaggcc
     7201 ggggtagcag acagcaagac tattatagca taattgaaat atccaaatga ttggattttt
     7261 gctataattt tagcgaggtg attgtgatga acaaatatgt tggtttgctt gataaaatcc
     7321 gagtaataaa aacgcaaccg ttattggttc gctttacttt acaaacgatt catgaatcga
     7381 ttaattgtgt agttgcagat attgaaatta tcgataaatt gctaattatg gatgatggaa
     7441 aatacaatat tgccgtcaca ggtcacttca ataaacgaaa tcagctagtt attgctagca
     7501 tgtatgttag aaatcccgat cattttacgc gatcgatggg catataaata aaagaagagt
     7561 tgtagtccta aatgaggatt gcagctcttt ttgttttaca tagaaacagg aaaagacctt
     7621 tttaggaaga cacaagtgcc ttctcaattg aaaaaccttt ctctcactcc aaccgccacc
     7681 gccgttcgag aagaaaggaa gtgaacgctg cacgttcact aagatatggt gtcttgcaaa
     7741 gcaagacaaa atagacaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     7801 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     7861 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattt attctggcca
     7921 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     7981 atcaaacatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     8041 ctatcatgca ccacatactg ttgaatgcga ttgtggagaa agagcgaaat gtatcaaaag
     8101 ctatcgtttg tatcaatgtc caacatgcgg gaaaaaatat accttgtctt atggcgatta
//
LOCUS       DAFELK010000087         7760 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFELK010000087
VERSION     DAFELK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.092"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="LP433_002661"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="LP433_002661"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBL2006776.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3285)
                     /locus_tag="LP433_002662"
     CDS             complement(2032..3285)
                     /locus_tag="LP433_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL2006777.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="LP433_002663"
     CDS             complement(3291..4214)
                     /locus_tag="LP433_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL2006778.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="LP433_002664"
     CDS             complement(4435..6927)
                     /locus_tag="LP433_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBL2006779.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="LP433_002665"
     CDS             complement(6934..7401)
                     /locus_tag="LP433_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBL2006780.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="LP433_002666"
     tRNA            complement(7537..7610)
                     /locus_tag="LP433_002666"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="LP433_002667"
     tRNA            complement(7668..7741)
                     /locus_tag="LP433_002667"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2162 a         1691 c         1246 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acaaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DAFELK010000088         7689 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFELK010000088
VERSION     DAFELK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.093"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..548)
                     /locus_tag="LP433_002668"
     CDS             complement(<1..548)
                     /locus_tag="LP433_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2006781.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAA"
     gene            complement(587..1705)
                     /locus_tag="LP433_002669"
     CDS             complement(587..1705)
                     /locus_tag="LP433_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBL2006782.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(1702..3801)
                     /locus_tag="LP433_002670"
     CDS             complement(1702..3801)
                     /locus_tag="LP433_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBL2006783.1"
                     /translation="MTINEVIYSPKHPLFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(3852..4673)
                     /locus_tag="LP433_002671"
     CDS             complement(3852..4673)
                     /locus_tag="LP433_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2006784.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLGCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(4670..5479)
                     /locus_tag="LP433_002672"
     CDS             complement(4670..5479)
                     /locus_tag="LP433_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2006785.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFVMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(5501..5995)
                     /locus_tag="LP433_002673"
     CDS             complement(5501..5995)
                     /locus_tag="LP433_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2006786.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(6007..6495)
                     /locus_tag="LP433_002674"
     CDS             complement(6007..6495)
                     /locus_tag="LP433_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2006787.1"
                     /translation="MFLKVGTGIAYMKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDYEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQEIKMTILDEVHVVNEEED
                     FF"
     gene            complement(6572..>7689)
                     /locus_tag="LP433_002675"
     CDS             complement(6572..>7689)
                     /locus_tag="LP433_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2006788.1"
                     /translation="IVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCGNYVFE
                     ALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGELLLLN
                     NLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMSGLGIS
                     DKLKDVFRHHLSDESIEVFTKEYRELRELIDQNDETYFDKTKLVITTSDLPRSFSIPN
                     INVYDILDGDGAANLKHILSSEMKPVEFNRLIQELIKFFSLEGIADRLNFLNPTIVMS
                     EVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKAEEPNYDMKPDEDEF
                     YYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
BASE COUNT         2317 a         1776 c         1295 g         2301 t
ORIGIN      
        1 gctgccatcc cctctaaaca atcttggtgg aagggacagt ttcctgaaaa attgtccttt
       61 ggatgtcgct tgatcaacat atgccccatt tccggatgac tgaacccttc cacgaaagtc
      121 ccattgaaca aggcaccacc tccgatacct gttcccacag tgaagtatgc aacacctgct
      181 aaccctttgc cagaaccagc aacatattca ccatagcaag ccgcattgac atctgttgtc
      241 cattcaatcg gaatattgaa atattgcttt agcgttccta caaaattgaa attttgccaa
      301 gcaagttttg gtgttgatgt gatatgaccg aaactcgttg atttgcattg aatatcaatt
      361 ggaccaaagc agccgacccc gatgcctgcc aattgttcct taaaaggttt aaaaaaatca
      421 atgacctgct tcattgtttc aactggagtt gttgtgggaa aactgactct ttccaaaatc
      481 gttaattcct cagtaccgac tgcacagaca aatttagtcc ctccagcttc aattgcccca
      541 tatatcatca taggttcctc ccttcgaata tgtgaaaaac acttcattaa cgcggcaagc
      601 gttctcgatc agtgaaatga cgtttagtat ttcctgaagc ttctgttgaa taccagtaag
      661 cgacactagc aacatcgtct tgccgctcaa ataagcgaac atcatcgttg ccgatttgtt
      721 gtaaagtgac cgataaatct tcggtaaaac agatggggtc ttgaagatgc caacgataaa
      781 gaccatgtcg tggcattgcg tcgtcaccaa aggcatgaac ggcattcaat tttcccgttt
      841 caaaacgatc tcttgtggca tctctatttg attggtaagg ataccctaaa aaggctgttg
      901 aatagttttt cgcatgtgga cgtccgaact catcgtactc atgaaaggcc cacgccccgc
      961 caaaataatc ttctgaacct gttgaggtta cggtcggata ctcactatcc ccatcaatgt
     1021 agaatttaaa ctcgccttcg ccccaccaat aacgttctag gcaggtaagc gcaaggtaag
     1081 tacccacgta atagccttga ccctttaatc gatcaattaa cttataatcc tcctgtaatt
     1141 tggtaatgcg ttcccgatgc caatttgcgt gaaaatatag gctattttct tccaattcgt
     1201 ccaccaaagc gtaatttatc gtataaaaaa atgaggacat atccttcgga tgtaaattct
     1261 cgatcgtaat tttagcggat gtttggaaag gcatttcgaa ataggaatta aagccccctg
     1321 taggattaac cactatcggc aacgagttca cctcgcaacg ctctccaaac ccattacaaa
     1381 agaaatcccc taaaggactt tcaacagcag ggctatccga cccatcccaa taaattctta
     1441 agattaaatc acgtaaaaca aaactgccaa attctgttcg atcacgaatc gtcatccaca
     1501 tatgacgaat tattcccgtt ccagtaatat ccgcaatcac agtttcttca ccagaagtca
     1561 gcggaattgc gccacgacct ttgcggcttg gtcctagctc gcttggcaac atcgcagctt
     1621 tacctttctc gcctgttgga ttttcgggag tgattgctcg actctggatt tttttaaatt
     1681 gggtaatatt ttttagtata ctcatctttt tctcctttga atgtgaatcg tttttccctt
     1741 ttctacgtga agaatttttt tcgtatcact tattttcaat ggcttttctg acaaatttga
     1801 aatactcaac tcggattgcg tacattcaat cgaaatgaag gcttgaccga acttcaaatt
     1861 cttccaagaa aacgttaaat tatcaacagg atcaatttgc aatactcctt ttttgaattt
     1921 caatccgaaa tattgactga tcattaggct gacaaaaaga cccgatgccc agccgcattt
     1981 gccgcagcca aagtctcgca cgacttctcc ttgttgagcc tctaagcgat acggccacca
     2041 ccaccacgaa ccgtctaaat ctgccaaaca aattagttct tctaatcggg ttacgaaagc
     2101 ttgagggttg tgcagctcgc tcattaaaac agtgataaag ccaggaaaag tggcgccgga
     2161 ttctaatccc caagtgatgc ctttgatttc ctcgctatag gttggattga aagaactagc
     2221 agaaaaggcc atggtgttct gatataaatg atctttatta tctaaaaatt gataaaaagg
     2281 catcaacgta gtgtctgatt cttctccatc atgcatcaat aaattaattt ttccatccac
     2341 aatcacatca cttaaaaaga ttaacccttg ctcaagaatc ggtttttgat agtgcttcac
     2401 tgaataggtt gttttctcct catcaccgat tccctccaaa aattgctcac caaaaggacc
     2461 atcgatagtc atttgtttac aaattgattc ctttagttta caggcaatgt ttttgtatcg
     2521 cttgctaaga ctcagttgtt ctagggcttc aaaaatttct gcaagtccaa tacaggcctt
     2581 ccaaagacaa agattgctgc cggtatgata ctttccaagt gcaaaggcgt ctgataacca
     2641 aacagatgga aaaagcattg gttcccctga ccgacgttga gctaatatgt cctcaataat
     2701 tcttgaagca ttcagtagaa cctgcggaca ccgctcaaag aattttgtat ccccagtatg
     2761 ttcaaaataa agactagcca gtaacgcact ggataacgaa ttactcagag aatgattgat
     2821 acctcctgta aattttgaac caggaaactt aacgccatat tgatcaaacc atagaaccgt
     2881 tttttgacat aactccggtt caaacatggt gaatggcaat gatgcgtaat acatatcctt
     2941 attccaaatt cgattagtag caggatagct gccccaattg ctgccgacga cctgtccctg
     3001 tcgattcata ccgaaactag aaaagctttg ataaagtgca cgacgataga gatggacaac
     3061 tctatcgttt ggcattgaca gctgcccaaa tagctgagca aaatagttca atgtttcctt
     3121 cagccatttt tcgatatcag attcctgaaa agtcattact tcttcaaaag catttgggtc
     3181 cacaaaagca atggcgaagc ttgccacttc ctgttgtgcg atcgtgtcct tatttccttt
     3241 ttgagaaatc aacacatttt gctgatccga atacttctct tgatacgaag gcacatcttt
     3301 cactgaaact tgaaggcttt cgtgtgtttc attcacaatg taaacctgtt gaacaagcat
     3361 acttaaacgc ttattagcca gtatgggagc aaaggatact acaatgacct taaacgtcga
     3421 ataatgatga atatatctag gcaaacagtc ttgaatcaca tcgacttcaa tacgatgatc
     3481 cgattctgac aaatggtaga caatcccgtt tacttcaacc tttaaggata acgaattggt
     3541 ttgagagagc tgtttattga cccaaacacc tggtttttcc tcagttagta aattttctcg
     3601 ataaaaggtc aacgtttgaa tcgtcccgca aacatcaagg tttgctaatg tcttttgatt
     3661 acttacatcg aaggtcaatc cctttacatc aggaatattc cgatagtagc tgtattcgtt
     3721 tgaagtagtc acatttccgt cgtttaactc agcattaaat aatgggtgtt tgggtgaata
     3781 aattacttca ttaatagtca tcttttccct ccttgctaaa aaaactgcag cctagtagct
     3841 gcagcttcct actatgcgat tccaagtaat gacaataaaa ttcccaagac gaccattcca
     3901 aaaataattt tgatgacgcc gactttttta tctagtaatt tgaaacagcc caatgttacc
     3961 aataacggta caattccttt aaaaatacta tcgaggattt cttggacatt cattagttct
     4021 tcgcccttca ttgaaaagct caaaacggta ttgaatttga ccatactgat cgtcattgcg
     4081 cctaccatga tcagacccaa gatactagca gcttttgtca gaatttcaat taacccgttc
     4141 gcatacagct tttcaatata tttagagcct aatgaatagc ctaaaacgcc gccatagtat
     4201 cgcatcaaat aattaggtat attgaacata actaaaaaga taattggtgc caaaatattt
     4261 ccggcattgg ctaagttgat cgctagtccc gcggtaacga cacgccaaac tccccagaac
     4321 aatgaatcgc caattccagc caatggtccc atcaaactcg ttttgatcgc gttgatactt
     4381 tccacgtcaa aaccagcttt ttcagaattt tccttctcca tcgatgccgc aatccccatg
     4441 acaaaggacg cgcaaggaat ggtcgtcgaa aaatactgtg tatgacgttc cagcgccgca
     4501 gctcgatctt cttcactttt gtagaaatga ttaatgaagg gcatcataga ataggcgaaa
     4561 ccaccgccgc ccatcgtcac cggattcacc gaagcataca tagtcatcga gcgccaaaac
     4621 atcttccgaa ccaatttttt ctcatcttta gaaattccat cagctaattt cattgaaaga
     4681 aatcctcctc ttcttggtca agcgttgcat ttacagcagc atcgctttga actgcatgaa
     4741 cagatatatt ttttagttgt agatctcttt gggctataac aattgcaata atcgttccaa
     4801 ctgcggcaat tgcaatcaat ggtaactcga gatacgccat aacaacggcc ccaaagaaaa
     4861 accacacagc aatattttta ctccaaagca tccgtaacag catagccatc ccaactgccg
     4921 gcagcagatt tccagcgact gttaatccgt tcatgatgac ctctggaata ttatccaaga
     4981 cgcttttgac aacatctgct ccaaataaaa cggcaaagaa tggaataaga gcataaagcg
     5041 catagtggac aaaccacata acgaagtgca gattgatgat tcctttttga tcaccagatt
     5101 ttgcaaattt gaaaaattta gcagccatcg gtccacatac aaaagaaaaa atcatattca
     5161 ttaactgtaa tcctaatact gctagtggaa agacaatggg aataatcgca tccacgtttc
     5221 ctcccatttt gattgcgaac gctgtagcca acccagcagc caaagaaggc tccgccgtac
     5281 tagagattcc gatattgacg acacccataa aaatggcttc tagtgacgcc ccgacaatca
     5341 accccgtctg caaatccccc atcaacgctc ctgctaacgg agcaacaaca atcggacgac
     5401 tcagcatgga catcccgaac atttcatgtc cagcaactcc aataaaaacg gccaaagcga
     5461 ctacaaatgc atcatacata atttttctcc ttcctttttt ctaaaaatca ctcaaaatag
     5521 agatagctga acgtttttcc atcgccggtg taggctgaaa aacggtatct ggataaagtt
     5581 caactaattc ttttaagtct tgaatttctg acgtcgttaa catcacttcc tttgataagg
     5641 ttttcttatc ttccgatggc ggtgtcattt tcccagcatt ccccacgttc attaattcga
     5701 tttccgttgg gaaagctttc gcaactttta ccgcatcttt gacattaggg actaaaacca
     5761 tcaagcgcat gtccttcgcc cgcggatctt ttaacaaatg aatcgcgtca tcaactgttt
     5821 taataatgac tttgacattc gatggtgcag ccatcttcaa tgtcatcttt tgaatatcgt
     5881 tggtagccgc ctcatcgctg gctactacta acccggttaa atttagactc tttgtccaag
     5941 tcatcgctac ttgtccatga attaatcgtt catcaattcg cactgcttta atcatttttc
     6001 ttcctcctaa aaaaaatctt cctcttcatt tactacatgt acctcatcaa gaatggtcat
     6061 ctttatttcc tgttggcatt tatttaccag ttcctgaata tcctcctttg ttaattcctt
     6121 ggttgccaat actatttcga gcagaattgg cagattaaag ccagacaaaa tagttacagc
     6181 aatctctttc tccaaaaagg ttttggtaat cttctgattg acacttccgc caaataaatc
     6241 ggtaaaaaca aaaatctgat cctgctcgtt cacctggttt acaaatacat tcaactcctg
     6301 ttcataatca cactcatcca cataagcatt aatcaccgta atctcttgaa ccttccccgt
     6361 cagtaattga atactgctaa gaaagcctga agctaagtga ccgtgagtcg ctattagaat
     6421 tttcttcata tggttaattc ctttctttct gttcactttc atataagcaa ttcctgtgcc
     6481 aacttttaaa aacattggtt taatcacgtt aattcacata aaaaaaagtg tctaacctga
     6541 aaaaatcaga ttagacactt ttttagacac tttatttttg aatatacggt cctaataatt
     6601 catagagcag cgaaagctca taagcattga ctttaaaatt atatttcatc tccattgatt
     6661 gaaaaatact tctcgaaaca taataaaatt catcttcatc tggtttcata tcataatttg
     6721 gttcttctgc tttttctgtc cgcgccaaga ataaacgttc catcatcaat gccgtatgca
     6781 tataaagatt tagttttacg cggccattta aagtgaaatg atagtaattt tcatatttag
     6841 aaatgactgt ttccacctca ctcatcacga ttgttgggtt cagaaagttc aaacggtctg
     6901 cgattccttc caatgaaaag aattttatca gctcctgaat caaacggtta aattctaccg
     6961 gcttcatctc agaactcaaa atatgcttca aattggctgc tccatcacca tctaaaatat
     7021 catatacatt gatattagga attgaaaagg aacgtggaag atccgaagtc gtgatgacca
     7081 attttgtctt gtcaaaataa gtttcatcat tttggtcgat taattcacgt agttctctgt
     7141 attccttcgt gaaaacttcg atggactcat ccgataaatg atgacgaaaa acatccttca
     7201 gtttatccga gatacccaat cccgacatgc aggaaatgat gatgttgcta ctttgagaaa
     7261 agccttcaaa gtattgaaca ttgattgaat acttgtctgc tgcatcctcc gcaatctgtt
     7321 taaatggcgc attcatcgtc atcttcaggc caatatcaag tgcaatggag gtcgtcaaat
     7381 tattcagaag aagtaattct ccttttaaat cgttcttgat ctgtgtgtag atttgattta
     7441 aagagcccat atctacgatc agcactagac tatctgtatt cacttgccgt ttcacgaaat
     7501 tccttgtcga ttcgacaatc tctgacacat tactctctac tggcatatcc aacgcttcaa
     7561 aaacataatt gccgcataat tgattcacta ctgcttgaat gctgctagcc gtactatctc
     7621 cgtgagcaag caacaggccc ttcagctcga tggattcatc tacataatca gataaagtca
     7681 cgacaataa
//
LOCUS       DAFELK010000089         7630 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFELK010000089
VERSION     DAFELK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.094"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(15..707)
                     /locus_tag="LP433_002676"
     CDS             complement(15..707)
                     /locus_tag="LP433_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL2006789.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1144..1713)
                     /locus_tag="LP433_002677"
     CDS             complement(1144..1713)
                     /locus_tag="LP433_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2006790.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1787..2110)
                     /locus_tag="LP433_002678"
     CDS             complement(1787..2110)
                     /locus_tag="LP433_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006791.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2264..3076)
                     /locus_tag="LP433_002679"
     CDS             complement(2264..3076)
                     /locus_tag="LP433_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006792.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3430..4278
                     /locus_tag="LP433_002680"
     CDS             3430..4278
                     /locus_tag="LP433_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBL2006793.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4423..5364
                     /locus_tag="LP433_002681"
     CDS             4423..5364
                     /locus_tag="LP433_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBL2006794.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5354..7525
                     /locus_tag="LP433_002682"
                     /pseudo
     CDS             5354..7525
                     /locus_tag="LP433_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1512 c         1372 g         2474 t
ORIGIN      
        1 gaggggggga ttttttatcg ttgtggaata tttaaatacc aacgcttgtc atgaaaatct
       61 tgtgctccac ccttagtatt tccttctgga tcgtttgtcg cacgcatcat gacgtatact
      121 ttcttattag ggaaatcacg catattgaaa gatacatgat agccaacatt tcctaaagta
      181 ttataagctt gatttacgtc tggtctataa atcccatcag ctcttactct agctagttct
      241 tttccagtat tgtagtccat aatgaaaata tactcgtatt tataattagc aatgtgccat
      301 ccagctacat gcaagtttgc gttttcgatt tctccgaact gatcaatgtg ggcgtaattt
      361 gttccatctg tcagcgtaga atttgcagca cctgctcgag ttggatcaat tactggttta
      421 tcctccgaag tagttggatt atcatccgta aaaccatgag ccaaatcata ggctagtttt
      481 tctttactta cacctatttc agaaagataa ccgtaaggat ctgtatgatc gccccaaata
      541 ttttgtgtta cccataaatg cgatttgatt cctggttggt tataaggagt gtctaatgtt
      601 aatggaatac catatttcat tgctgaatct cttgccaatt caacgtatac tttatagttc
      661 ttttcaaaag tttctttatc atgtgtgtgt tgtaactcga tttgcacagg acttttggct
      721 cacgaggttg tcctactcta catcttgctg atagatatgc tgaaaggaaa acaccaacat
      781 tatgttttgc tttttcagct agaacgagac aagcaggaat acctttagaa gatatcaaag
      841 gttttttagg tcataaagat gtttccacta cacaagtcta tgcccatatt tctcccgaag
      901 tgaaaaaaag atcaatgaat caactagaaa actatataga agagcaaata aaaaagcact
      961 caaattgagt gcttttttaa gctcactatc actaaaacta tcactaattt tatttataag
     1021 cgaacatgtt tctatcactg attttttaaa tctagcgaaa aacccttatc ttaaaggcgt
     1081 tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc ctagaagtgc gaacatggtt
     1141 ttcttatagc tcatgtagaa aaattttctt gatgatgatt ttatccatca attgagattg
     1201 actgttttgc tctcctatga tttcagctat gattgtccga ttttgcggtt ttcttcttaa
     1261 ctggtagttg attttcccag tttccatcaa ctcgctaagc atatccacga ctccgccaaa
     1321 tccggtcttt ttcgtaataa aacctagtgc taccattcgt tcatctagat tttttgctgt
     1381 aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg gccagctctt ccatcccttc
     1441 agcattggat acgacggaag ctgttttgtt aataggttct tcgtttattt cttttggttc
     1501 tttcctctcc actttcactg tttgacgaag gacatctagt tcttgcaaga gcgtttcgta
     1561 ttgttcttgg gtcagcatca cgccagctac tttttcacga ttaaatatat atacgccagt
     1621 tcccgcgtct cgcgcttgag caaatacatc catcggcgat cgtttcactt ctgtgatcga
     1681 agatgtggga acttctaatt tctttaattc caatggattt cctcctttac taatcgcttt
     1741 ttattatagc acagactgac ttgttttgat cttttttcca aaggttttat cggtttttgc
     1801 ctaaccagta attgatatcg gtaagaagtc tttcgatacc aaatgaagga tggtacagat
     1861 acgttttttg atcttcgtta tggtctagtg gaaaaaaatg atcgatgatc actagatctg
     1921 cataccgagg cggcttattt cgagtacata catgtataga gatccgtttt cgatgtctta
     1981 gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg gtgttcatag cgaaaaaaaa
     2041 agacgatttt cacttcagga gggtggacat ctaaataccc tcgttcctgg agtgttttca
     2101 gtaaaagcat cccccactct actgcggggt gtgcaagtgc ttgttggatc gctagccgaa
     2161 attgatatag tttatctttg gaattgggaa atttttctaa tgtttcctga taataacgaa
     2221 cttcttctat cagccggtca tggataccaa ttacgtaacg aagtcattct tggtaaagta
     2281 cttttgtcag ctttgatttg ctttcgctct caaattcgct attcagccaa aacagcgaat
     2341 caagcttttc agtcacaatc gtcaatttcc gatagtcttg tgtctcttct atccgtttcc
     2401 accgcttttc agtaatctgg ttacagctca agcgcaaaat tgctagataa tttttttctt
     2461 ttattggcaa aatctgctcc tctctaaata gcaattcagg aaacaattca aagaatagtg
     2521 ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt tctttgcttc aataattgga
     2581 tgaacatctc agaaaaggac tgctctccat catctgcaaa aaaatgcgga aaatctttca
     2641 aaaagcaaaa cagcagatat cttacttttc tttctgaacc aaagatctgt gcttttttat
     2701 aagaaaaaga aaggtggtac tcgccaaacc actttctcaa tcgctcttgc gtagaacgat
     2761 cgtacttctg ctcgtaaggt tcattcaata gcagattttt cagtaaacaa aacgggggtg
     2821 attggatcag aaaaacaaac aagagataag gttcgctata tccttgatca taaactaact
     2881 gaacggtttt cttatgaaga atcagctgaa tgggacagtc gctttccgcc aaacgtttca
     2941 gatgccgatc cactgtttta acatcgattt tcagttcttc agctaaatca gcttttcgcc
     3001 agatcaaatc tttcattaga ttgattagtg aaaataaatt ctgtgcattt tttgataata
     3061 gtttttgcca tctcatcgat catttctcac ctgatttcta aacatattgt ttgatcaaaa
     3121 tgggttcact cctaaaaaga taaaaaactc cctttctatt tatttaaata cgcaaatctt
     3181 cctcattatt ttttatttta ctcaatttaa tcgtattctc atttcaaaac gaatgtactt
     3241 taaaaaaaca taataagatc actttgcttg taggatgtat tcccttccat tacaatgaaa
     3301 taaatagcga ttttatgaga aggtgatgtg aaaatggaag aaaaaataga agaatccaaa
     3361 caaaaaatcg atcagttgat ataagaatta gaaaaagcgg tcatcggcaa acgttcaact
     3421 atccaattga tgatcgtggc cctattagca ggtggtcatg tcttattcga agatattccc
     3481 ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag ctgtacaggg aaccttcagc
     3541 agagtccaat gtactcctga tctgctgcct agtgatattc ttggtttttc cgtatacaat
     3601 tcacaatcaa aagagtttga atttcgtccg ggaccgatct ttaccacgat cttgttagca
     3661 gatgagatca atcgtacgac tcctcgtact cagtcagcac ttttagaagc aatggccgag
     3721 aatcatgcaa cgatcgacaa caatacatac cctctagaca atcatttttt tgtcttagct
     3781 acgcaaaatc caatcgagta cgaaggaaca tatcctttgc cggaagcaca gctcgatcgt
     3841 tttttattcc gactacaaat cggttatcct tcttttgatg acgaactttt gctacttttg
     3901 gataaattcg aaaaagtgtt ggataactta aatgaagtat tgaacagtta tgaaatagaa
     3961 gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg aagtggcatc ttatgccttg
     4021 cagttagtgt cagcaacaag aagtcatgct gccatccagc ttggcatcag tccacgagga
     4081 agcctttcct ttattcaggc agcaaaagct tatgctttaa tccatgggag aaattacgtc
     4141 acgcccaaag atttgcagga tttagttcct tacgtgtttt cccatcgcct gattttttac
     4201 gatcgttcat tgaaggaaga cgaaaagaaa caaatcattc atactcttgt tgcacaaatt
     4261 cctattcctg tgaggtagat tgaggtagac aatggaaaaa atcaaagatt atttcattaa
     4321 ttttgtgtta tttctggtat atttcatcat tgtgcttttt gctcttgtat tcaacaattc
     4381 tttaggctgg ttcttgttgg ccttttttac tctttatgta tcatggagct tgatttcatt
     4441 aagcagcttt ctaaagaaac tttcggttac ttgtacattg cagccactcg tttatcgcaa
     4501 aaaaagtatg caggttattt tttccatagc aaaaaagaga actttttctt tacctctccc
     4561 tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa aacaagagat tttgattctt
     4621 acaaataaac cgcaagaagt ccaattgctt tggcagccaa aagaaagagg atgccatgaa
     4681 acattaactg tcatttttac agcctatgat agtctaggac ttttcagaaa aagtgcaaaa
     4741 agagagatct cttttcctgt gactgttctg cctgcttttt gtaagattca agcagaaaaa
     4801 ttacagagag ttctggaaaa aaaacagcag ctgaacgcgt accaaagagg tcttgatttt
     4861 cgggaacatc gcgcttatcg tccaggtgat tctttcaacc gaatcgattg gaaattgtct
     4921 gctcatactc aagagtggtt ataccgtgaa tacgattatc aagaagaaga atgttctcct
     4981 cttttttgct tttggggttc gcccagtcca aaatttgaac ctctgctaga cttgtatttt
     5041 tctttatggc atttgagaaa agaaaagcag ccggaacttc tgatattagg caaccgcgcc
     5101 tttcatggca aagaccccgg tcatacctat tttgcttctt tggaagctgg cgatgagaaa
     5161 acttttttcg cacacttgaa aaaatatgca aaaaaacaaa tcgtcctctt tgttcctgag
     5221 aattctcctg aagtctcaga agctattgaa acattgtcaa aagatcgaac ggtttatctt
     5281 gtttatttcg tagaaaaaca actcatggtc caagaaaaag acaagatatg ttcattgcca
     5341 ggaggtgaat ggattgacga ttaaacggga aaaatggctg cgtggcgttt actcctttgt
     5401 gatactaagt gtaggtgctc cgatatttgt agtagctaat caattgcaaa acagctacct
     5461 tcttatccta actattggtg tcctatgcct tattgtctgc tgtattccta aaaaatgggt
     5521 acgtttgctg ctttctttgc cagtaatgat aggttgtttg tttttatatt ttccttcgaa
     5581 gacattttcc atattatgga tcttacagtt tttttcgtca gttacagagg aattcttcca
     5641 tctatcccaa ggtaaacttt attatttgcc agaaaagaca gctttttttc tcataatgtt
     5701 gctgatctat ttatttatta cattgaccgt ggattacgac tattggtacg caccctttct
     5761 ttctttgatg gcttacttca tgatgcttac cgtttttcgg aaaaaagatt tactgtacga
     5821 aatgattgcg gtagtaactg ttttgttcgt gtatctggca gcaaggcaat ttttctccat
     5881 ccggttgttg tcgagaaaca ctcgattcca gtcattgact acagttctgc ttatttgttt
     5941 cttaactttt agcgctatct tgcctttata tcttccgaaa gtacaccaat ctctcgagga
     6001 aacgagtgaa ccgatccgag aatatcttaa tgatgaaggg ctttatgaca cactccatga
     6061 gtatcaatta accggaagtg caagaacagg cttcagtgag aatgatgaac agcttggtgg
     6121 acctttatat gataatggcg aagttgtttt tacagcgaac caaaaaggaa atggctattg
     6181 gaagatcgaa aataaaaatc attacaccgg ttctggatga atagaagatc aggacgcacc
     6241 catccaacca atccaagaat tccctgttga catcacgagc taccaaaccg ttatagaaga
     6301 caaagaaaac attacattga ccctaaaaaa acaagctttc ttaccttatc cttatggaaa
     6361 tactaccttg actgattttt cattagctag tggacaaacg ctttactatt tgcctgaaag
     6421 ccagcgattc attcctgtcc cgaatgaatc gacacgttct gcaactttac aaacagaaag
     6481 gttagttttt acgagagaag aattaaaaag cagtcagtta aaagctgatg atttagaaaa
     6541 tcagcagaca aatcttcaat tgccaaaaag tttgcctaaa cgtattgagg acttggcggt
     6601 cgaattgacc aaaaatgaag caactttaat tcgtaaagtc gaagctgtct aacagtattt
     6661 aaaaacaagc ggaaatttcc gctattccaa aacggatacc gggcatactc caaaagaaca
     6721 cgattatgtg gattatttcc tctttgattc aaaagtcggc tattgtgaca acttttcaac
     6781 ttctatggtc gtccttcttc gaacacttgg tatcccagct cgctggacaa aaggttttac
     6841 aaatgggctc agaacaggca cagataatca agggaatgag gaatacagca ttctcaatag
     6901 tcatgctcat tcttggccag aggtatactt tcctggattt ggctggcttc catttgaacc
     6961 aaccccttca tttgccaatc caatgggttc acaaccagtt gctgaaacaa ccgaaaccgt
     7021 ccagcctgct atcgaacaac caaatgaaag cgaaaatatg gcagaaacta tttccagtga
     7081 gagatctgag gtcattccat cagaagaaac aacactcaca ccagcttata aaatcgtctt
     7141 attcagcctt ggagtgtgtt tatccgtctt gttgttcttt ctattgttat tcagaaaatc
     7201 tctgcgctgg acaagttatc ttatctatct tcattttttt gcttctacta atacgattgc
     7261 atatcaaaaa cttcttaacc ctttggaaac attggtaccg cgcaaacccg cagaatcttt
     7321 gcaggaatat agcctgcgaa tagaacaaga attcaagcta gatctgcgtt tcattcgatt
     7381 aactactcaa tatgaagcag aaatatatgg acgacaagca gatccggtaa aattcgataa
     7441 aaaaacctat ttagaaataa cgcatataat aagaaaaacg gtatacaaaa aaattctgac
     7501 aaaagggagc cgcttcaaaa aataagataa aatttctgga gaatctactt ctcgaatgcc
     7561 gagaaccagc tgattgagta tcgattactc gaaaaaaagg ttgtgacacg ttttttgtca
     7621 caaccttttt
//
LOCUS       DAFELK010000090         7596 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFELK010000090
VERSION     DAFELK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.095"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(939..1352)
                     /locus_tag="LP433_002683"
     CDS             complement(939..1352)
                     /locus_tag="LP433_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBL2006795.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1808..2293)
                     /locus_tag="LP433_002684"
     CDS             complement(1808..2293)
                     /locus_tag="LP433_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006796.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2432..2647)
                     /locus_tag="LP433_002685"
     CDS             complement(2432..2647)
                     /locus_tag="LP433_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBL2006797.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2871..3671
                     /locus_tag="LP433_002686"
     CDS             2871..3671
                     /locus_tag="LP433_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2006798.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3690..5558
                     /locus_tag="LP433_002687"
     CDS             3690..5558
                     /locus_tag="LP433_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL2006799.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5551..6042
                     /locus_tag="LP433_002688"
     CDS             5551..6042
                     /locus_tag="LP433_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBL2006800.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6030..6584
                     /gene="srlA"
                     /locus_tag="LP433_002689"
     CDS             6030..6584
                     /gene="srlA"
                     /locus_tag="LP433_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBL2006801.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6602..>7596
                     /locus_tag="LP433_002690"
     CDS             6602..>7596
                     /locus_tag="LP433_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBL2006802.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1442 g         2234 t
ORIGIN      
        1 ttactatgaa taacataata agaaagtaaa gtggattgat ttgagatctt tttatacttc
       61 aaaaaagata acacccaact ttcaaaaata tgttttggaa gttgggacaa acgagttaat
      121 acattttaat acattatttt ttattcaaaa aaaatagcac aatggcaaag atcgtaagag
      181 agatcataag ccccaatgaa tgactaaaaa gaaaagcaga atcacatgcc atatcatccc
      241 atatttcttc aagaaaataa ataagcggga aaaagggaag gaatagtaga acatcgatcc
      301 agcaccattt ttttcttctt ttgaaataac ataaaacaat aaacatgaac gtgcagggaa
      361 gtaaaaacaa agctttactc ataactaaca aaataccagc tccttttatt tttttctccc
      421 ccacattcaa agagtaacaa tggtatgtac ttaataatag aaaaatggat caacttgtat
      481 gaataacagc tgaaaagatc tgcaccaaat aaaaaacttc cagccaaaac tgactggaag
      541 tttatttttt tctgaaatat tctaacacaa atatgaaaaa gatggccgaa gctaataagc
      601 cgatttcgta gcaaaacaat gagataccag agtcgtaata ataaaatcct ctaatcttat
      661 ggataaaata gatcatcgga caagcagata agagtaagta tttgttaggc cttttgaata
      721 agtaaaagaa agcactggtc attatgataa atggtatcca aaacaaaagt ttacttaaga
      781 caatcaaatg atcaactccc atatttttta ccaagagaga tcataacatc tttatcgtaa
      841 aaacaaaata tttttttgct cattttgaaa atttaaacat actcgttctt atccaaatat
      901 ataaaaatcg cccctcattc atcgagaggc gataagttct aatttaactc aatttttttt
      961 gtttcttttg gctgataagc tgttttaggt aataccaatt tcagcacacc gtttttaaag
     1021 gttccagtga ttttttcttc atcaacatta ggaagataga atgaacgttt gtaagagacc
     1081 gaatgtcttt ctttccgtac atagttgcca tcttctttat cttctgtatg ggactcatga
     1141 ttggcggaga tcgtcaaagt attatctgaa tattcaactg tcgtgtcttc tttgtcacag
     1201 ccaggcatat cagcagttag tttgtattct ttttcatttt cgactaaatc tacttttgga
     1261 taacttgaaa cacctaaaaa atcattgaat gctggactaa acacgtcatt gaaatcaggg
     1321 aacatgtcgc gaatgctagg tacatttgcc atttttgatc atcctttcaa taagtatttt
     1381 ttatttatcc ctatttacgt aataactcta ttttgaaaaa aatgcaagta taatggttag
     1441 ctttgtgaat atttcatcta atacgataca aaggctatct ttctaatttg aaaaagggat
     1501 cattaaaata ataagaagaa aatatgtcaa aaggtaaaaa agtaaattct tctatccaaa
     1561 tatagaaaaa ttgaatctag aaaaccgccc gacaataaat ttcattaact cagttgaccg
     1621 aaaatgaagt agataccaaa aatttatcaa gagagcaagt agagaagtga gtatattcat
     1681 aagagaaata gctgtaacga attattaggt taatgcaaat gcttatttat actccgtata
     1741 actttctcag aaaaaatgat accaataatg acttgctagt actgtaaatc cgtataatat
     1801 catctaatca aaatggtgtt ccatttgcat ctgtcatcgt aatcgatcct tcgggtgaca
     1861 ctcgataaaa accaacgctt ccagatcctc cttgggaacg gatttgtttg ctggaagctg
     1921 tgaacaaata atctcgatca attttttgat aaaagctaat aacaatatcg tcactttgta
     1981 attcggaacg gtgggcaata agaaatagaa gtgctttgtc agagttttct aatggaagag
     2041 aaggtacagt gctttcttgc atttcagatg ttgaagaaat gctaaacgac tgaatacttg
     2101 attggctatg ttgcgaatct acattaccag tagaagtatt agtaatggaa gtagtagaag
     2161 tacttttagt tgaaccaacc tcagttgttg aaatggctgc tgaagattct ttaacagaat
     2221 tctttgtttt atatccacag gcagaaaaaa gtattacagt tcccaacaag cctgcgtaaa
     2281 tccctttatg catgatagct cctcctaaaa tagattatct ttattcagta tatcacttaa
     2341 acaaagaaaa gcagatggtt taaaatgaaa aaaccttccc aataaaggga aggttcatga
     2401 agataataac ttttttaata attatagctt tctaatatct ttcatcaact tttctagtaa
     2461 tcattgggaa aaatttcaag cagtagatcg cacaaatacc tacgacgata taaatgatct
     2521 tcgcaaaaat agttgttgaa ccaccagcaa tcatagctac taaatcaagt tcgaacaagc
     2581 ctaccaacag ccagttcaac cctcccacaa tcaataaagt taatgcaata gcatctaaag
     2641 ttttcattag aattctcctt tcttaaatga taaaacaatt atatatcaaa aagagaaaca
     2701 ttgcttatat aacgctcagg aattttagca atctatgcaa aaagatgaaa attttttttg
     2761 ctcttccatt agtacacatt ttttagctga agctgtaaat ttcatgtctt aatttttttt
     2821 agtgagcttt tatactggat ttgtaagaaa aaagaaggag aggatcacat atgtcggatt
     2881 ggttggatat tgcaggaaaa gtagtaattg taactggagg ttcctcagga attggaagaa
     2941 gtatcgtcga aaatttgttg aagcagaatg cacaagtagc gaattttgat gtaactgaat
     3001 gccgtataca gcatgaaaac ctactatctt taaaagtcga tgtgtcttct aaaacggaca
     3061 tagaagaagg gatatataaa gtaatgaaac atttcaagac gatcgatggt ctagtcaata
     3121 atgcaggaat aaatattcct tctcttctaa tagatagaaa tcatccaaaa agcaagtatg
     3181 aattatcaga acaagttttt gataagatga tcgctgtcaa tcaaaaaagt gtatatttga
     3241 tgagccaagc agttggaaga atcttggtgc aaaagggatc aggagtgatc gtgaatcttt
     3301 cttctgaatc aggattggaa ggatcagaag gacagagctg ttatgctgct acaaaagcag
     3361 cgatgaacag ttttactcgt tcttgggcaa aagagttagg aaagaggaat gttcgtgtgg
     3421 taggtgttgc accagggata ctggaagaaa ccggtttgag aacacaagaa tatgaagaag
     3481 ctctttctta tacgagaggt ataagcgtcg aacagctgag aaacggttac agtcgaacaa
     3541 gtacgatccc tctaggaagg agtggtaagc tgcaagaagt ggcggatcta gtctgctatt
     3601 atctttcaga aagatcaagt tatatcactg gagtcacgac taatatttca ggaggtaaaa
     3661 caagaggata aaggataggg gggacgcacg tgacgctagt aaacagatgg taccaattat
     3721 tgaaattact agtcactcac aagaaagttt caatccagga agtgcaaaaa gaaatcaaaa
     3781 ccagtaatca aaccataaaa aaagatattg gggagttgaa tgaagaaatt gccggtattg
     3841 caaaaatcat ccaaaaaaac aaacattttg aacttgaaat ttatgatttt gatttttttg
     3901 atgagatcat gcaaggaaaa ttgaaaacag ccagtgattt caattcggca tccaaaagaa
     3961 tcgcttattt actaaatagg ctgatcgaaa cagaggattt cttacgtatg gatgatttgt
     4021 ctgaagaagt cggtgtcagc agaggaacag tggtcaagga tctaaagaca ttaaaagaga
     4081 tgatcaatga ttttgatgta aagattacag gcacaccaaa taaaggacta agaataatag
     4141 gagatgagct agaattacga ctacttttat tttattttgt ttctccctac ttttcagaga
     4201 cgaaaacaga acagtttcta gaagaaaaac aagcaatcaa acattttcag aagaagacga
     4261 atgctagtaa acaagaaatc acccttttaa cgaaagttat cggtatttct ttgaatagaa
     4321 tctctagtaa ctatctgttg aagaagccca tcaatcgtta cagtgggtgt tttgaatata
     4381 tccaagaatt caatgaactg atcaatcagt tggaagaaat ctatgaacta actttgagcc
     4441 aatatgaaaa agattttatc agttttcctt tgaacatcat caacacaagt ataacgatga
     4501 taaggaaagc taactctgat ttgcgcttat atttcgaccc catgatgatg cgtattcgac
     4561 gattagatct cattgatctg gatgagtcct tcttatatca agagatgaaa cagcacctct
     4621 ctttattgat aaatcgggta atttttcgtt atcgattgac tgatttattt tatggtgaga
     4681 tagaaaaaaa gtatcctttt tcttaccaaa tcgctagcga atgcatacaa gcattagaag
     4741 ctatcttgca acataagatc tctaaagtag agatcagcta cctaacgttg tatttggagt
     4801 tagcatttcg atatcaaaaa gagcattttt cctctaaaaa agtagccatt gttcatacga
     4861 caggaaaagg aacagcatta atgatccaaa gacaaatcaa aaggatattg gggagggata
     4921 tacaaataac acatgtttca gaagaacaat atgaaaaagt agatctaaac aaatatttcg
     4981 ctgtttttac aacgattccg ttaaaaaatg taaatgaaga gacaccggtg atccatttga
     5041 ctaatctttt tgatgactct tggttaaggg cacaatggca aaaagcaaaa aaaaagcgat
     5101 tagccgggtt tcattctact gtttttttct atcaaatatg gaaagaaaaa aagacgtatc
     5161 aagaatattt aaacaaatta gtcgctcctt tgatcagagg ctattatgtg gatgaagaat
     5221 ttgaaaaaag gatcttgaaa agagaatatc agcaaagcac atttgttaac aaagaatttg
     5281 cttttcctca cacaaccaac cagctatctc aacacattgt tttatcagta gggctaataa
     5341 ctgatcaagg tttagcagaa acaggaggaa atggagttat ttttttattt gccatacctg
     5401 aagaaatgac ggctgaagtt gagaatgaat tatttgagct atacgatatc ctatttgaac
     5461 tcataaaaat gggaatagat gagtttattg aattagcacc gacacaagaa tcatttttaa
     5521 aactaatcaa aagtaaagga gagagacttc atgaatgata tgtatctatt catagttttc
     5581 gcagcttcag cttatgtgct gcaagcagtt atcagttgga agcaactaaa gcatttcaat
     5641 caaacatata gcgaactgcg aagaaaagga aaagtagcga ttggtaaacg acctgggaaa
     5701 atccgttcag gcacgattgt tatgctagct atagacgatc atgatcaagt tttagaagtc
     5761 agaaaaatgc aaggggttac atctttggca aaatttcatt cattacctgt ctatgcgggt
     5821 gaagatatcc attacatcga tcgttaccat ccctcagttc gagcggaaga tcgtttgaca
     5881 caagcagctt tagaaaatgc cagagaagta tacttacgaa tagaggcagg aaatgaaaaa
     5941 agtgaacaac cttcattgcc ttttattgct atgctcaata attttcggat atggaaaagt
     6001 acgatcaaag aaaaaaggag tgacaaacga tggatatcat aacaaaattt gctgagggat
     6061 ttatgaggct gttccaaaca ggtgcagaaa cattcataag ctggatgaca ggaatcgtac
     6121 cagttgtctt gatgctgatg gttgcaatga atacgctgat tgctttttta ggtgaagacc
     6181 gagtaacgaa agtagccaaa ttatcagcga aaaatccgct tactcgttac cttgtgttac
     6241 cgttcttatc tgcttttatg ttgggaaatc ctatgtcatt tacaatggct cgtttccttc
     6301 cagaatacta caaaccaagc tattatgctg ctcaagctca attttgtcat acgagcaatg
     6361 gtgtattccc ccatattaat cctggagaat tgtttgtatg gatggggatt gctcaaggga
     6421 tcgaaacctt agggctaaat tcgatggagc tggctatccg atacttgctt gtgggactgc
     6481 tgatgaactt tattggtggt tggataactg attttactac tggatttgta tgcagacagc
     6541 aaggaatcgt tcttagcaaa aaagtagagc tttcagttga ttagagaaag gagagtttta
     6601 aatgtatggt gatattaaga tcgtaagagg aaacggcggg tatggaggtc ctttgattat
     6661 taggccgaca aaagataaac acaagttcat ctatgtcaca ggtggaggtg agaggccaat
     6721 gatcgtagat aaaatagaag aactgacagg tatggagtct atcaatgggt tcaaaacatc
     6781 aatacctgat agtgaaatcg cgcttgcaat cgttgactgt ggagggactc ttagatgtgg
     6841 aatttatcct aaaaaaggga taccaaccat caatatcgtt tccacaggaa aaagtggccc
     6901 attagcacaa tatatcactg aagatattta tgtttcagca gtagggttag aacaaataca
     6961 gccactaatg gaaactgatg ataacaaaga aacagtaaat actgcatctc cagataaaaa
     7021 gtacaaatat gatacttcta aaaagataac cgagcaaaaa gcagagcagc aaaactggat
     7081 agcaaaaatt ggaatgggcg cgggaaaagt agttgctaca ttcaatcaat cagcaagaga
     7141 agcagtagat acgatgatcc ggacagtgat cccttttatg gctttcgttt cccttttgat
     7201 tggtgtgata caaggttctg ggatcggtaa tgtatttgct aacattatgg cacctttagc
     7261 aggaaatgca gttggattaa caatcattgg ctttatttgt tcactgccat ttttatctcc
     7321 tttgcttggt ccaggggcag ttattagcca agtgattgga acattgatcg gtgtagagat
     7381 tgggaaagga aatattcctc cccaattagc attaccggca ctatttgcta tcaatactca
     7441 aaatgcatgt gattttattc cagtcggtct aggtttggaa gaagcaaaag ctgagacagt
     7501 agaagtaggt gtaccatcag ttctttattc aagatttctt aacggcatcc cacgagttat
     7561 cattgcttgg gtagcaagtt ttggattata tagctg
//
LOCUS       DAFELK010000091         7367 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFELK010000091
VERSION     DAFELK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.096"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(99..1229)
                     /locus_tag="LP433_002691"
     CDS             complement(99..1229)
                     /locus_tag="LP433_002691"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBL2006803.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="LP433_002692"
     CDS             complement(1878..3080)
                     /locus_tag="LP433_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2006804.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="LP433_002693"
     CDS             complement(3140..3343)
                     /locus_tag="LP433_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBL2006805.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="LP433_002694"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="LP433_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="LP433_002695"
     CDS             4880..5692
                     /locus_tag="LP433_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2006806.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="LP433_002696"
     CDS             complement(6716..6868)
                     /locus_tag="LP433_002696"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL2006807.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..>7367)
                     /locus_tag="LP433_002697"
     CDS             complement(7059..>7367)
                     /locus_tag="LP433_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2006808.1"
                     /translation="LGVKGQNLLADDSFWQIEAFYLAQCAYNTTLMFSPDRIIFGGGV
                     MKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGIIGGLALARKAVRNKQP
                     "
BASE COUNT         2268 a         1477 c         1133 g         2489 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaa
//
LOCUS       DAFELK010000092         7306 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFELK010000092
VERSION     DAFELK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.097"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(39..2138)
                     /locus_tag="LP433_002698"
     CDS             complement(39..2138)
                     /locus_tag="LP433_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2006809.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLANA
                     ANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQDPVED
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(2439..3263)
                     /locus_tag="LP433_002699"
     CDS             complement(2439..3263)
                     /locus_tag="LP433_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006810.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            complement(3260..4015)
                     /locus_tag="LP433_002700"
     CDS             complement(3260..4015)
                     /locus_tag="LP433_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2006811.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            complement(4028..6004)
                     /locus_tag="LP433_002701"
     CDS             complement(4028..6004)
                     /locus_tag="LP433_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2006812.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            complement(6057..6728)
                     /locus_tag="LP433_002702"
     CDS             complement(6057..6728)
                     /locus_tag="LP433_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL2006813.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            complement(6788..6997)
                     /locus_tag="LP433_002703"
     CDS             complement(6788..6997)
                     /locus_tag="LP433_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006814.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            complement(7064..7303)
                     /locus_tag="LP433_002704"
     CDS             complement(7064..7303)
                     /locus_tag="LP433_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006815.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
BASE COUNT         2014 a         1496 c         1102 g         2694 t
ORIGIN      
        1 aaagaaaaca aggctgattc tcagccttgt ttttatattt atttgagttt taaaactaca
       61 tagcccaatg atgctaaagt aagaaataat atacttccaa taacagttag cactaaatga
      121 ttcgatccag tttttggcac aatgatctga ggtaagttag gttttacccc aatcgttact
      181 acattagttg ctttctcaat actttctact gaaacttttg cttggttgtc gatatccaat
      241 tcttcattca aaggagtttt agctgtaaat atcagctgaa tttctcgtcc atctaaaaga
      301 tttttactta agaaatcagc ggaagcttcc cacttcagcg ttcttgaatt gctatcatag
      361 gttagtgtac cttctgaagt aatatctttt cctgtactca tatctatcac tcgcgcagaa
      421 ccttctttat acgtcaaacg atcttccact ggatcttgaa tactaaattg cttgtaatga
      481 tctgaggcaa tgtctacacc ttttgtatgc catttttgtg tgactagata ttgtacttca
      541 gatcctgcat ttaaaggagc tgtaggcgtt ccttttttac catcatttcg accatcaaca
      601 tctttcccat cttgttccac ttttttattt ggtttaagag agaaatagtt ttctactgta
      661 tttgtttttt gtgttccttt gttcggatca ttgttaaacg ttacagtagc cacatttggt
      721 gcaattcctt ttgcatcatt ttttgctctc atatggagct gcaaaatata atccctaccg
      781 taatttgcag cgttagctaa aaagctgtca gaagcagtat aagtgactgt attacctgat
      841 acagttaact ttcctcctgt atcagctttt ttccaagtac cattcgcttc aacataccac
      901 aatgcgccat catagttttt cccatccgat accatatcaa aatttttgct gtcaaaggta
      961 tcagtgattt taaatgattt gtatttgttc attgtgttga ctgttaatgc atcaaacttt
     1021 tggtgaatat gatagtaaac atctgatcct tgtggaatca cttttttgtc aatattgtgt
     1081 gctgcctctt cagtattagc tttgttaaac acttcttttg taggcttcga tggttgtggt
     1141 gtccatagca atgcagtatc aaagctaaac atcatactat tcgtatttgc gccaatcatg
     1201 aatgttgggg aagcgccttg aagcgtatac gttacaccac ttctgtgata agtatcagct
     1261 cctacaacat cggtgaaatg atcattcgag ctataagcct tttctgcacg tcctcccact
     1321 acttttgaag ttaaattgtt tgttgataac gcaggagctt tgtattctgc acatgctgta
     1381 tctgttgtga caaaataagg taagctaccc attttttcat acccaacaaa ttctctcata
     1441 tcaatattac gttcaccgac agattcatta ttgtcattat accaagacac acgttgctga
     1501 tactgtccat ttaaactgta aatggataga aatgtatcgt ttaaatcaat accagctgct
     1561 ctcatcgatc tcatttttga ttgaatttct ggctgtggtt cactcaaagc tacttttgtt
     1621 tttgttcctg catacttaaa ttctagtttt gcattcatga cattgattga ctgcatgaaa
     1681 aatcctcgat aaatattttt atcaaagagc aaataattat aatacttttt gccattaatt
     1741 gttttagcta atccgtcttg gttaacccca gcgtgcgcta caaaattaga aaaagtcacg
     1801 tcacaatcaa tttcttttcc tagataagta cctacttttt gataatgggc aacgattttt
     1861 gacgtacttt tcaaatcttt gacttttggc caagcaagta ctttttgttt tttagttgaa
     1921 tactcatcta gtatcttaaa tccattgatc ccagttactt cgatatttct caatgaatca
     1981 ctatcatgat aaagcaccag attattattt tctttgattt gactcggatc aactttttct
     2041 aaggcctgga ctgcagttcc cctcgcaaaa agaagaagga acaaaaacaa cactaaagta
     2101 attactcttc ccgtagtgca atgaatttta ttttccataa tgccctccat ctaatatttt
     2161 tttaaacgat cgtaagcttt tcattctttt tttcctaata cccacgttac caatcctgta
     2221 agaagaacca aactaaccat aaaaattgga ttgatcaaga gctttttaat cacctctaat
     2281 ggcatggaag cacattgaat gtttagaaaa tgaatgaaca atcgttgata tcttggataa
     2341 attgataatt gagaaaaaat taaaccgcaa cacaatattg ttgcggctaa aaaggataga
     2401 ttaaaaacta atattcttat tattttcatc atttcatcct aattatcaaa aaataattga
     2461 gcaaaaaatt cccaacaatt ttcaaaaaag ttcttcttta caccagttga cacaactttt
     2521 ttaatttctt ctttcggctc tgatttctct gatttagggt ataaccaaac atccgtcaaa
     2581 aattcacctt tttcatttga aacaggtgtc aataaaacaa tatcttcact gtttgaaatg
     2641 ttttcagggc ttgattcatt aacgatatag tatgcttgtt ttttgtttgc aggtacttca
     2701 atggaaaatt caatcacgcc ttcctgatca tcaatcgttt tggtttctcc ttcagccact
     2761 tttttcaact ggtcgtatga aagttttttt gctcgatctt tcaattttga ctcaattatt
     2821 tctacagatt gatttttctc attatcatct tgtgacattt cttctaagat attcgtgata
     2881 tcgtagacaa taaacttcgc gccattgata ccttcttgct gggctacttg actgccttga
     2941 ttgttgattt gattcgaaga aataattttt tgaatatgaa tggcttgctt gatcacttgc
     3001 gtatcttcta cgtcttgcgg cttttctgaa gtctctgaag aactttctga cgttggattc
     3061 gttgattcag taaagcttat atttgaatct gccgtttctt ctgtagtatt ctccgaactg
     3121 tccgtttcgc ttggtgcagt aattgaatta tctattgttt gagtggtact actatcactg
     3181 ctgtcagcga aagacagttg cgaataagct acagtagaaa agagagctgc tacacaaaca
     3241 aacagccatt ttctcttatt cattccgatc tcctccttat ttttttataa ataaaaataa
     3301 taggaacgca aaaaaaagcg aatagcagtg ctaatcgcca atccaatgaa attgatttcc
     3361 tattttttgc ttttttctgt agttttaaat cttctttact gaaggaaact cgttcaccat
     3421 acactaaaaa gcggtgtgag ttgacacctt ttggtgtgca tgtcattaac gtgatcctat
     3481 cttggtcttt ttcaggcata agataatcta aataattttt ttgtaattct tctgctttaa
     3541 cttcttcaat tcgataaatt tgataggcat gttgttcttc atttacctta ataaagaatt
     3601 tttgcccttt ttttactgaa ggcaaatcat cgaaaagatt atctttataa agtccactgt
     3661 gccccgcgat taaaggattt ttaccgtttc ctcctgtaat atcgccagtt ccttccgtaa
     3721 tccctacacc attctctaaa attttgtcgg aagttccgtc ataaattggt agttttaaag
     3781 aaatacttgg aattgtaaga acaccaacag gatcgcctaa ctctattttc gcaacatcca
     3841 aagaagaatc tgttttttca agattttcaa tggctaaaat tctttgctgt tgttgaaatt
     3901 tcgctacatt tgtttccaca actggaatta aatagactgc tactgccgac agcaaccaaa
     3961 aaaatatcat cagtttgtgc atgactcttc tttttggggg cttacgaata atcattagct
     4021 gatccttcta ggctttcttc ttaaagtaaa caactgcaga aagtccccct gctcctagca
     4081 acaagcaaga gatcaatacg taagattgga aaccgttgct accagtcatt ggtacggaag
     4141 ctttttgatt atttttgatc gtgattcggt tttcttcttt gtatgaatct ttgtctactt
     4201 tgaaagagat ctcttttgtt aatttttgat agttttcagg agcttttgtt tcttccagtg
     4261 agtaatctcc ttcagttaaa ccagtgattt caaaatgacc ctctttatct gattttagga
     4321 ttgctgcatt tgctacatcg tctacccaaa ctgcttcttt gacaccatct ttatctgtat
     4381 cagtaagtcc accgtagtac ttaccttctg cattcttagc tgcaaattct gcgccttcaa
     4441 gcggtgttgc tttgatacct gttccaaata ggccgctatc gacttttaag aattttgcgc
     4501 cataagtcac aacgtcagct ttcgtttttt cgtggtgttc ttcctgatta aatggattat
     4561 tgttataaac gaaatccacg ctatttgtta atggatttgc gatttcagca ctatcattca
     4621 caaacatgtt ataagtcatt tttagatctt gaccatgtaa attcgcaact gtatcactta
     4681 cttgtccatt atttacgata aaatcgatca caaaaccact atcagaattt tcgattttat
     4741 agtcagtatt ttcttttaat acgactgaac catcattatt tgttacttta atatctgctt
     4801 tttcagcaac ataagaaagt cctttacctg ctgtatctcc ccatttaaat acactgtaag
     4861 gagaagtttc gcttttcaca ccgtttactg tgataccgtc tgcgccacct gcaatgtctg
     4921 ttggaatatg aatcgttcct tgataattta ctgcgtcacc aatttggaaa gaatgttctt
     4981 gtcctgttcc atttgttact gttttatcga tcactggtgc tttatagttt acgtatgaag
     5041 cttttaagtc acttgtcacg ccatcattcg taatttcaaa ggttaattta ttgtgcgcat
     5101 cgttgcgagc gtctgcgcct aataaatatt gatctgctgt tggttcttga tctgatccca
     5161 ctacaacttc cgaaggaact tccacaaaat agtattttcc taacgtcaaa tcagtcgcag
     5221 tcagctttcc ttgatcatcc gatacaagat cacccaattt tgttcctttt ccaggttcgc
     5281 ccttgtataa ctcaaatttt gcccctttta aaagggtttg tttgctttgg tctgcgccat
     5341 cgtcaccaaa tttcgttaat tcaaaactca acttagaaac aatgttctta ggatacaaat
     5401 gaatattttt taaaaatcct gatcctgttt tatctgtcat tggcgcaatc acaaccattg
     5461 gttttgcttt ttgtgtgact aatccagcag cggatttact ttcataaacc acatatacat
     5521 tccctttgga attgacatag gctggttgat cagtaaaagt gatctcacca ttttcatcta
     5581 cagctgaagt aattttgttg gttgcattct tgacgtactc actgttagat cccttgtctt
     5641 ctacatcttg tacaatctcg tccactttcg cgttggttag atcagaatct tctctcggta
     5701 atacttgatc cgtaatattt cctaacgtaa actcaacatc accataatct gccttgttgt
     5761 atttcgttac acctgtagga tattgatcgt gcgtataacc atcgtttttg atcccgtcaa
     5821 tatcaacatt caattgcgtt ccttgatcgt acattaattt atgaaccgtg atattgacct
     5881 tctctggtgg tgttttttgc gtgacatctt ctgcatgtac ttgatacccc tgaaagcagc
     5941 ctgcaatgat tcctaacatt ccaacaagca ttccagcttt ttttacatac cgatttattg
     6001 ccatttttta ctctcctcat ttcatatttc aacgactcgc gttgattaaa accttgttat
     6061 tgtagctctc cctgtaccac gtatctttct tttccttgtg acgtataaac acaagtaaac
     6121 aacgttaata agggtttctc tcctttcttt ggcaaagaca agaaagagtt ctcttcagga
     6181 acgccatcga ttaatttaaa gtacccaggt acgataaatt tacgcgttac cttgtaacga
     6241 tagacgccat cgttactaac taagtccatc acctccccta atgacaactt ttgaatatca
     6301 gaaaataaaa cacctggcat ttccatgtta tgacctgcta ggacatagtt tcctttgccc
     6361 atttcggcat cttcataaaa ataagtagcc gctccaagac tcaaagtgta ttgatttgcc
     6421 cctttaaaaa ttggcaatgc taaaccaagt gcaggaatct gaatttgtgc aaatacttgt
     6481 ttattgacgc ccatttcgat tgcttctttt tgtatggaca acatttgccc caaagacata
     6541 tcattattga cgttcgttgc atcctcctta taactctttg catgtgcatt gatttgatct
     6601 acgggcatct ttttttctat attttgctta aacacctctc cttcatgttt ttggtagcta
     6661 acatagccaa acacactgca aaagacgatt aaagtgactc ctaaaaaacc aaataaccat
     6721 tttttcatcc atctgcctcc tttcagacaa aacaaaaaaa ctttttctca tttccataga
     6781 aaaagtttta aaaatgaatt ctataagttc gtctcaactg ttcaaagttt ttcattgaac
     6841 ctaacaaaca agctttctct tttcctgtta actgcatatc attgatatat tgcgcgacag
     6901 ataatctttt aaggtgtttt tgcttcatcg tttttagtaa cttttcttcc atttctttcg
     6961 acactttttt tctgttttcg atttcttcat aattcatgag ttttcctacc ttccttgttt
     7021 tttgcaaaaa taaaaaagcc tatgatcaca tacgctctac acttcagtct tgggttatct
     7081 ttttctttcg tttaattact ggccgtgctg gtttcaaatc cttgattcca ttatgggttc
     7141 tccaataatc gaattctttt cgcaatcttt ctttttccat atctgttcct ttagataagg
     7201 ctttgaatac ttctttaggt gaataaccac gagctaacag ctgtacatac cttccttttg
     7261 tcaaagtatc catatccatc gcctctaaaa ctggtcgcgc catcta
//
LOCUS       DAFELK010000093         6643 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFELK010000093
VERSION     DAFELK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.099"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(1..859)
                     /locus_tag="LP433_002705"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="LP433_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="LP433_002706"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="LP433_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL2006816.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="LP433_002707"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="LP433_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2603..3421)
                     /locus_tag="LP433_002708"
     CDS             complement(2603..3421)
                     /locus_tag="LP433_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2006817.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="LP433_002709"
     CDS             3582..4271
                     /locus_tag="LP433_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL2006818.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="LP433_002710"
     CDS             4285..5787
                     /locus_tag="LP433_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2006819.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="LP433_002711"
     CDS             5800..6276
                     /locus_tag="LP433_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2006820.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="LP433_002712"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="LP433_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atg
//
LOCUS       DAFELK010000094         6641 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFELK010000094
VERSION     DAFELK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6641
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.100"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            157..2832
                     /locus_tag="LP433_002713"
     CDS             157..2832
                     /locus_tag="LP433_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBL2006821.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            3014..3253
                     /locus_tag="LP433_002714"
     CDS             3014..3253
                     /locus_tag="LP433_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006822.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3269..4642
                     /locus_tag="LP433_002715"
     CDS             3269..4642
                     /locus_tag="LP433_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006823.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4646..6280
                     /locus_tag="LP433_002716"
     CDS             4646..6280
                     /locus_tag="LP433_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006824.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6443..>6641
                     /locus_tag="LP433_002717"
     CDS             6443..>6641
                     /locus_tag="LP433_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006825.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2324 a         1073 c         1335 g         1909 t
ORIGIN      
        1 cagtctgagt tgtgatttcc aaaatcacaa cttttttctt ttgtcaagat tttgagtggg
       61 atatattttt gtagaactga agatcatgaa attatgagag gttggaggta atgtagtcat
      121 acaaataaaa attttttaga aagtgagtgg taattaatga aaatgaatca cacttcaatt
      181 cagaagcatt tacaactgtt aaatacactg gggatttctt atgttaattt gagaactttt
      241 tctacattaa acaagaaaac cgtttctcat attttttcta ctgcagattc tcaagcaatt
      301 attaactatt tagaaaaaca gaaattgtct gaaggtacag taaacataac ttataatcct
      361 attaaacaag aggtgattac acaaaaaaag cattctgtga gagacaatga tattgaaaaa
      421 attcggtttg tatttattga tattgaccct aaaaggaaag agggaagtgc aacagatagc
      481 gaaaagaaaa aggcagaaaa tgttatggaa caagtagaac gttatttgaa agaaaagaga
      541 atagaatcat ttgtaaaagt tgatagtggg aatggctacc atatttttct tcccataaat
      601 gaacaaccaa ataatcacga gacgattctt actattcaga attttcttca attacttcac
      661 cgaagatttg gagtagaaga tgaagttgat attgatactt ctgtttataa tccttcaaga
      721 ttatgcaaat tagttggtac accagcggtc aaaggaaagt ccacaaaaga gcgtccgcat
      781 cgtttatcta gtttcctttc tattcccgat aacatagata gaagtaattg ttttaaaatt
      841 cttgaacaga tagttgaaga aaattccatg atgtcaacct ctagagtaaa aagccatcca
      901 tcttttagag aagtgttacc ttttattcaa gcagactata aacaatggtt agctcactat
      961 cctgaattaa cttataccat aaaagagggc gatcataaag gagttacctt acttatattt
     1021 gacgaatgtc cattaagaaa acacacgaat aattctaatg gttcttgttt gtctgttacg
     1081 gctgataata agattcgatt tcattgtctg catgcttcgg ataaaaataa agatattcaa
     1141 gactttgtaa aaaaatatcc gttgccaaaa cctgtaaatc cttctgtaga atcattagaa
     1201 tccaatcaag aatattattt tgaccagttt aaactgaatc aagaaggagt atttttggtg
     1261 aaagaaggtc aagaagaaaa agttgcttgt ccgatgttta ttaagcaaat acgcaaaaat
     1321 atcgaacaaa aagtcattac acttgttctt gcctattatg tcgatcattg ttgggatgaa
     1381 atagaaatag aaggtggatg tttacaaact aataatttta aacaattagc aaaacatggc
     1441 ttaatcatta aagctagaag agaagctgaa gtcgttgact ttttacagat tcaacgggag
     1501 aatgctccaa tcttttttga acatgaatct cttggctgga aaaaagaaaa tgaagcaatg
     1561 atttttcagt tacaagattc ttttggacgt gaaattcctt ctgtattaac taaaaactca
     1621 tgctaccaat taacaactaa tggtacagaa gcggaatttg acgcattggt tcataagtat
     1681 gttttaggaa cgaacttaga acttgcttgg tcgattggta ttgcttctat tgtgttaggc
     1741 tatttaaacg ttacgaaggc taatactttt ttgagtttac taattaacct acagggcaag
     1801 agcacaacgg gtaaaaccac tacgttacac tttattgcct ctttatttgg aaatccaact
     1861 acggttctta gaaatatgaa tgctaccaat aaagccatta taaagctagc atcaaacaat
     1921 cagggaggtg ttccactaat actagatgag ttaggagcag caactcaaaa taactttagc
     1981 tcgttgatct atcaattagc ttcaggagaa gaaaggctaa gattagattc taattgtcag
     2041 cttatgccac aagagacttt ttctgttttg acccttacct cttctgaaga gcgtttggaa
     2101 aattatttca atgagaaatt aactggtttg aaagttcgat atatcgaatt ttctgatatc
     2161 aagtttacaa aggatgcgaa tcacgcagag aaagttaaaa gtctttcttc taatactttt
     2221 ggttggggta taaagttatt tcttttgaaa ctctttgaac aagggattac aaaaattgaa
     2281 gcaacttttg tcgaagctca aaaaaaacta tgggctgttt tacctgaaca ttctttgaag
     2341 caacgcattg gtaataatct agctttgatt tatagtggag ccctcctaat tcaagatata
     2401 ctgggctatc ctttacgatt agagcatata cagacggtgc ttattaattc gtacgaacag
     2461 ttaattgtag atactagttt aggaagtgag caaacggtat ttgaccgagt gaaaacattg
     2521 ttggtgatga atagccataa atttttaaca aacagtgaca acaaacatac gcccagtacg
     2581 atttggggaa aagtatcaat tcaaaaaaat ggggatatta aggtaaatat ttttcctatc
     2641 ccgtttgagg acttgttaag gcgagaattt caagtaaagg atctaaccta tctttttagg
     2701 caattgcttg attcgggtaa tatgtgtgca gaaaaaggga gaagaacgaa acgtattcac
     2761 atgaatcgtc aagttcttcc aacatacgag attctattac cttcttcact caaatcgtat
     2821 tttcgattgt aatttagaat aaaccaaagt atgaaagtga ggcaccatgt tatggaaata
     2881 tttcttattg atttagcaaa acaactgatt acttatctgt atgatagcga gcaaacccaa
     2941 acggaagtaa atgaagcttg atctatgctt catttacttc attcaatcaa acatgaaaga
     3001 aaggaaaatt ctaatgacta aaaataaaat gacactaaaa gcagaggttc ttctgtatat
     3061 tcaagaacat ttttcaaatc aagccttttt tacaaaacca atttacttgg atttcgaaat
     3121 aagaggggta tctgctggat ctatcggggg tactcttcaa gcgttgaaga acgaaggata
     3181 tttagaaaat cactttgtgc aacgttcgtt caatagaaga gtcgtgaaaa aatggtattt
     3241 agttcattca tagagagggg aatcaagcat gcgtgtggct tgttatgatc gaacgtctgt
     3301 ttatgaagaa gcgaaaatta gtaatgacgc tcaatatgat gcagtgaaag agtatgtttt
     3361 agagaaatat gaacaaattc cccaacgatt ttcagacaaa ggagaatcag gggaaaaagc
     3421 ggagcgtcca gcttttcgac agcttagagc ttgggtttgt gcgtcagaag aagagggggt
     3481 gatctatgtt tggcgttatg atcgattggc acgtcaagcc aaaatagcct tagaatttat
     3541 tgagttgtgc caacaacatc aggttcaagt gtattcgatt tctgaacctc ttcctgcttc
     3601 tttctcacac gcgtcaacga ataaactatt tgtgcaatta ttgttcactt ttgcagaaca
     3661 acaacgaaac gtcattattg agaatgttcg tgccggactt tcctataaaa agcaacaacg
     3721 gcaatatttg tcttctgcgg taccatatgg gtatcgttta gtgaatggga aaatccaaca
     3781 agaagtacac gaagcaagga ttgttcgcta tatttttcaa ctttatttga ccaaaaaata
     3841 tggctacaaa aagctttgtc aacgattgac gcaacaaaag cttttcttcc gcgaacgtcc
     3901 ttttcagccc tatcatattt atagtatcct aaaaaatcca ttgtactatg gcgaaatcaa
     3961 aggaggatct ttggggaagt atctaggaac ctttgaaccg attctctcga aagcaacctt
     4021 tttacaagcc caagagattc gccaatcaag gtgtacagct aaaaaagata cgtatctgta
     4081 cttattacgt caaaaaattc ggtgtccctt ctgtggtcgt catctgagtt cgaagtatca
     4141 atggaataca aagaagacga agacgcttca ttattatcat tgtaccgacc gaagctgcca
     4201 aggaattttt cttcgggcag aaagggttga gtcagaagta ttggaaaaga tacaggcttt
     4261 ttttcaatac gaaggcgtct atcaagcctt gattgcccaa ttaacgcaac aattagccga
     4321 aaagcgaaaa gatgaaaaac gcaaagtaat ccaacaaaag aaacaagaag cacaatggat
     4381 taaggcattt gaagagggca attgttcact ggaagaactc aagcaacaac tgcaagctct
     4441 tcaaaagccg atgtctactt cttcgtttct ttcactccaa cagtgtgaag caaaagtgaa
     4501 agaatggctt caactaaaag acctctctag tcgacaatta ttatgtgact atgtttgtcg
     4561 gattgaggta acaaaggata aaacagtttg tgggatttac ttccgacaac tgacacaaaa
     4621 tattttagaa aggaacgaat gatctatgga aatgatacaa accaaacgag tcgcattgta
     4681 tattcgcgtg agtacacaag aacaagcttt agaaggacat agtattcaag cacaagaaca
     4741 aaatggacga cagtttgccg aacggatggg ctatgaagtg gtagaagttt atgccgatga
     4801 aggaatcagt gggaaatcca caaaaaatcg gttcgcctat caacgaatga tgaacgatgc
     4861 tcggaaccat cgttttgatc tactagtgat ttggaaattg acccgtctcg gacgcaatat
     4921 gttagatgtc ttacaaacag tcgaggaatt attgcgatat gacgtaggat tacattcgat
     4981 ctcggaacaa tttgacgtga ccacttcgac aggtaaattg atgttacaac tccttgggag
     5041 tttcggtgaa tttgaacgca accaaattgc ggagaatgtt caaatgtcaa tgcaaagctt
     5101 agtgaaagat aaaaagcgtt atgcaggagg ccgacgttta ggctatgtca gtggtattga
     5161 cacgaatggt caaaaacaat tggtcattga accagaagag gcgaaaattg ttcgtctgat
     5221 ctatgcaaaa tatttaggcg gagcagggta tcgagcgatt gccaattttt tgaatcgtca
     5281 aggatatcaa acagtcaaaa agaatgcttt ttctaccacg gcagtcaaag atatcttacg
     5341 caataaaatt tatgcagggt atttagaata tgcgcgctac atcaattggg aaaccaaacg
     5401 acggaagggg aagaatccga gaccgatttt agtgaaagga acccatgaac cgattatttc
     5461 ggaagaagat tatcaaaaag tacaagaacg ccttgcttta gaaggaaaac aacccaaatg
     5521 gaaccataca ggtgaaaatg tattgacagg cttgttacgt tgtccagaat gtggcgcacc
     5581 gatggcagcg agtaatgtca caaataccct aaaggatggc acaaagaaac ggattcgata
     5641 ttattcttgt tcagtctttc ggaataaagg agcaagtgtg tgtcatgcca attcgattcg
     5701 tgccgaacaa gcggaaacat ttgtcgccga ccgattaaag gagatcgttc agctaccaga
     5761 agttcttccc cgattggtgg cagcgttaaa tgaagaaata gtgcgacaaa gccaaccatt
     5821 ggaacaagaa ctcgtggtgt tactggaacg aaaggaagaa ttgaagacta aaattgaaaa
     5881 atgggaagct gctttggaag atagtcctga attgtttccg atgttaaaag accgcttaga
     5941 cgaattgact gaaaaacgac gacagttgca cattcgagaa aatgaaatct tagggatctt
     6001 tcaacaagga gagccgattc aagtcaaaga tgtccaacgg atattgacta gtttggatcg
     6061 ttttcttgcc cagagtgaga agaagcaaat caaagccttg tatcgtacct ttatagagaa
     6121 aataaccttt gatcctaacc ataaggagat gttggaaatt acgatgaaat tcacgcatgc
     6181 cgtggtacaa caattgaatg agcaatatca aatagccgta tccaaaacaa aggatacggc
     6241 tatttttgtg ttaaaaacac cctttacgtt aacgatctag tctaggttat atcaaacaac
     6301 gttagagggg cgctaacgct tctctagcga tttgaaatcg ttagagaagt agttagggag
     6361 gtccttatca taaataggga tatttattaa tgaatatttg aaatataatt gtatataaga
     6421 attaaaaaga gtggggatag atatgaaaaa gatgggtaag tgtattttat gtgaaaaata
     6481 cactgaactt actaaagaac atgtaccacc taaaaaatca gggaatactg gaggtaaaaa
     6541 gaccagaact ggtaatttag atgatttcct taagagcgat tttacaaaag gtgattttcc
     6601 gaaggggatt aaaaggaaac ctcaaggaaa tgtttattat a
//
LOCUS       DAFELK010000095         6639 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFELK010000095
VERSION     DAFELK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.101"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            113..1198
                     /locus_tag="LP433_002718"
     CDS             113..1198
                     /locus_tag="LP433_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2006826.1"
                     /translation="MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPN
                     TIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREE
                     TTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRV
                     KKKQIRTLRSKEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIH
                     LTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFG
                     KPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTT
                     LNTYVHLSDQDMKNEFNKYLERKEHKK"
     gene            1195..3087
                     /locus_tag="LP433_002719"
     CDS             1195..3087
                     /locus_tag="LP433_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2006827.1"
                     /translation="MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPS
                     AIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKM
                     LDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
                     YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYF
                     KQLVKRYCKLRLNVDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSE
                     LNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEF
                     VLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKM
                     KKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQ
                     NIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETL
                     KNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGC
                     PHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQI
                     IGSLTG"
     gene            3094..3471
                     /locus_tag="LP433_002720"
     CDS             3094..3471
                     /locus_tag="LP433_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2006828.1"
                     /translation="MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNS
                     IAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVME
                     LEKENKKLQNQIQKLYGDLYNKE"
     gene            3622..4404
                     /locus_tag="LP433_002721"
     CDS             3622..4404
                     /locus_tag="LP433_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HBL2006829.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(4530..5261)
                     /gene="erm(A)"
                     /locus_tag="LP433_002722"
     CDS             complement(4530..5261)
                     /gene="erm(A)"
                     /locus_tag="LP433_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HBL2006830.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVIAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            complement(5319..5378)
                     /locus_tag="LP433_002723"
     CDS             complement(5319..5378)
                     /locus_tag="LP433_002723"
                     /inference="COORDINATES: protein motif:HMM:NF033690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythromycin resistance leader peptide"
                     /protein_id="HBL2006831.1"
                     /translation="MGTFSIFVINKVRYQPNQN"
     gene            5770..6432
                     /locus_tag="LP433_002724"
     CDS             5770..6432
                     /locus_tag="LP433_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2006832.1"
                     /translation="MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGC
                     GSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIV
                     SRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCF
                     KFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVW
                     TK"
BASE COUNT         2388 a          898 c         1269 g         2084 t
ORIGIN      
        1 atagtagtta aagtagttta agaggagata ttaaagggat attttacttt aaataaaaat
       61 taacaaggtt tataatttgt agtagttaaa gtatttaaag aggtgggaac atgtgaaggt
      121 tcaaaggata gaagtggaga ataagccgta tccattgtat ttattactag ataaagaata
      181 ccagctaata gaaccagtaa tgaaatttat taaatactta gataatactg gtaagtctcc
      241 taataccatt aaggcatact gctatcattt aaagttgctg tacgagttca tggaacagag
      301 aggtgttatt cttaatgata ttaactttga gttgttagca gacttcgtag gttggttgag
      361 atatccttca gcatcaaatg taattgatct tcagtcaaaa aaagccataa gagaagaaac
      421 gacagtgaat acaattttaa atgtagttat gagttttctt gattatttaa gtagattagg
      481 agaatttaaa tcaattgatg tatttaaaca agcaaaggga agaaatttca aaggattttt
      541 acatcatgtt aataagggta gataccaaaa gaatgtctta aagttaaggg ttaaaaagaa
      601 acagataaga acattgagat caaaggaagt taagcaaatt attgatgctt gtcatacgaa
      661 aagagataaa ttaattttaa tgcttatgta tgagggtggt ttaagaatcg gtgaagtgtt
      721 atcgcttagg cttgaagata ttgtcacttg ggacaatcaa atccatttaa cacctagaga
      781 tgttaatgtt aatgaagctt atattaaatt aaggaaggaa agaacaatac atgtgagtaa
      841 agaacttatg tcactttata cagattactt gatatatgag tatagtgagg aattggagca
      901 tgattatgtt tttatttcct taaaagaagg ctattttggg aaaccactaa agtaccaaag
      961 tgttcttgat ctagttagaa gaatagttaa aaggactgga atagaattta catcacatat
     1021 gcttcgccac actcacgcaa cgcagctaat tagggaagga tgggatgttg cgttcgttca
     1081 aaagagatta ggtcacgcac atgttcagac aacgttaaat acctatgttc atctttcaga
     1141 tcaggatatg aaaaatgagt ttaataaata cctcgagaga aaggagcata agaaatgaat
     1201 gcttctagta aaaggaaaat tattagtcag agtgagatta gcaaaaaaat agctgtaatg
     1261 aatgaagaaa tgcaggggtt ttgggctaat aatagttggg atataagaaa atgtccacat
     1321 ccttctgcca tagaattaag taagaatcct gctttaagga atcgttgggt tcgttttgaa
     1381 cgtgttaaaa atctgtggtt aagaacagaa ttgaaatatt tttattttta ccatttaaac
     1441 aatggaatat ggaatgcaaa aactgtctgg attagaaaag gaacagtaat taataaaatg
     1501 ttagatttct tagatttaaa gtatcctagc attacttcaa ttactgaagt tcctattgaa
     1561 aaagcaatga cggagtatag aacttatttg acaaaacggg gtgttagaat taccactact
     1621 aattataaga ttactgctaa tcaagaaaaa acacctgtaa aagctaattc ctactatgtt
     1681 actaatctaa aacaatttat ggagttttat gagaactttt attttgatgg agaggagtgg
     1741 gataaagacg tttgggatag acgtaactta cctttgccag atgataaggt taacccaaca
     1801 caatatgaat atacaattaa ctttaaaggg tttcggaata catattttaa acaacttgta
     1861 aaaagatatt gtaagttgag attgaacgtg gatagctttt cctatgtaag tgatattgcc
     1921 caaagactta aagagttctt taattttctg gacatgaaat ttaaacaagt tcagagagta
     1981 caccaattaa cgagagtgga aattgaagca tatttaagtg aactaaacat gatgggaata
     2041 aaacctagta caataactgg gaggatctct atattggaag gactatttag tacccttctt
     2101 aggctagaat gggatgatgt tccttccaaa atattaattt attctgagga ctatccgaaa
     2161 ataccaagag caaaaccacg ctttatagat gaattcgtcc tagagcaatt gaacagtcat
     2221 cttgataaat tacccgaata tatagctacg atgactatga ttgttcaaga atgtggaatg
     2281 aggataagtg aattgtgcac cttgaaaaaa ggctgtctat tagaggacaa agatggagat
     2341 ttctttttaa agtattatca atggaaaatg aaaaaggagc atatagttcc aatatctaaa
     2401 gaggtagctt tacttattaa agttcgggaa gataaagttt cagaggaatt tccagatagt
     2461 gaatacctct ttccaagaaa agatggatcg ccattaaaac aagaaacatt tagaggtgag
     2521 ttaaataaat tagcttatga gcaaaatata gtggataaat caggtgagat ttatagattc
     2581 catgcccatg cctttcgcca tacagtagga acaagaatga ttaacaacgg gatgccccag
     2641 catattgtgc agaaattttt ggggcatgaa agcccagaaa tgacaagcag atacgctcat
     2701 atctttgatg aaactctaaa aaatgaattt actaaatttc aggaaaaact ggttaccaat
     2761 aatggagatg tgcttgatct agatgaagat aatgaagtcg atgatgtaga gcttcaatgg
     2821 ttcaagaaaa atataaatgc acaagtgctt ccaaatggtt attgtagatt gccagtagta
     2881 gcaggtggtt gtccacatgc gaatgcatgc ttagattgca ctcacttctg taccagtaag
     2941 caattcttac cacagcacga agaacagtta gagcgtacag aagagttatt agccatagct
     3001 aaggataaac aatggcaaag acaagtagag actaatagcc gtgttaaaga gcgtttagaa
     3061 caaatcattg gaagtttgac ggggtaatta tcaatggata aacaagttag aaatacaaca
     3121 gaaattgtac gtttggcgaa gcagaaatca aaaaagacaa gggaaaaagt agacaaagcg
     3181 atttctaaat tttcgattga aggtaaagtt attaatttta attcaatagc aaaggaagct
     3241 aatgtttcta aatcatggct ttataaggaa cacgatatta ggcaaagaat cgaatccctt
     3301 cgtgagcgtc aaataacagc aaatgtagtc tcaaaaccca agaaaagttc tcgttcggag
     3361 gaaatcctta ttaaaacctt aaaaagaaga gtaatggaat tagaaaaaga aaataaaaaa
     3421 ttacagaacc aaattcaaaa attatatgga gatctgtata ataaagaata attattaatc
     3481 tgtagacaaa ttgtgaaagg atgtacttaa acgctaacgg tcagctttat tgaacagtaa
     3541 tttaagtata tgtccaatct agggtaagta aattgagtat caatataaac tttatatgaa
     3601 cataatcaac gaggtgaaat catgagcaat ttgattaacg gaaaaatacc aaatcaagcg
     3661 attcaaacat taaaaatcgt aaaagattta tttggaagtt caatagttgg agtatatcta
     3721 tttggttcag cagtaaatgg tggtttacgc attaacagcg atgtagatgt tctagtcgtc
     3781 gtgaatcata gtttacctca attaactcga aaaaaactaa cagaaagact aatgactata
     3841 tcaggaaaga ttggaaatac ggattctgtt agaccacttg aagttacggt tataaatagg
     3901 agtgaagttg tcccttggca atatcctcca aaaagagaat ttatatacgg tgagtggctc
     3961 aggggtgaat ttgagaatgg acaaattcag gaaccaagct atgatcctga tttggctatt
     4021 gttttagcac aagcaagaaa gaatagtatt tctctatttg gtcctgattc ttcaagtata
     4081 cttgtctccg tacctttgac agatattcga agagcaatta aggattcttt gccagaacta
     4141 attgagggga taaaaggtga tgagcgtaat gtaattttaa ccctagctcg aatgtggcaa
     4201 acagtgacta ctggtgaaat tacctcgaaa gatgtcgctg cagaatgggc tatacctctt
     4261 ttacctaaag agcatgtaac tttactggat atagctagaa aaggctatcg gggagagtgt
     4321 gatgataagt gggaaggact atattcaaag gtgaaagcac tcgttaagta tatgaaaaat
     4381 tctatagaaa cttctctcaa ttaggctaat tttattgcaa taacaggtgc ttacttttaa
     4441 aactactgat ttattgataa atattgaaca atttttggga agaataaagc gtcctcttgt
     4501 gaaattagag aacgctttat tactttaatt tagtgaaaca atttgtaact attgaaaata
     4561 gaaagaaatt gttccttcga tagtttatta atattagtga catttgcatg cttcaaagcc
     4621 tgtcggaatt ggtttttagt gaaaagaaca cgatattcac ggtttaccca cttataaaca
     4681 aaagatcgat actttttgta gtccttcttt gaaatcaatg gttgatgtcg ttcaagaaca
     4741 atcaatacag agtctacact tggcttagga tgaaaatata gtggtggtac ttttttgagc
     4801 atttttatat ccatctccac cattaatagt aaacccaaag ctcgttgcag attttgcaat
     4861 cttttcgcaa atcccttctc aacgataaga tagctatatt tagcctgact ttcaaaggta
     4921 attcttttga caatatccgt actgatgtta taaggaatat taccatatat cttatagttt
     4981 atatgttttg ggaaggaaaa ttttagaata tccgtttgaa tcacttttat attctcagag
     5041 gggtttaccg cttctttagt cacttgacat aagcctccat caatttctat agcaataact
     5101 gatcgactca ttttgactag ctctttggta aaatgtcctt ttcctgatcc gatttctatt
     5161 acgttgtctt gtttactgat attcgtgtga ttcaatattt cttttacatg ctttttagaa
     5221 gtaataaaat tttgcgtgtc tttagggttt ttctggttca ttataacctt ctccttactg
     5281 gttataatga actgacatta agcgttcatt ataaccaatt aattttgatt tggttgataa
     5341 cgaactttat taataacaaa tatagaaaaa gtacccatac ttttatctcc tttccatttt
     5401 tttcattatg aatgagataa agtaatttct actactgcga tactggtgca cataattgaa
     5461 acctccttat gtaactgaat atgattgtat catcttttca ttttagaata aacctttata
     5521 tgtaattttg cacttgacac ttcagatgga cgttttcttc aaaataatat gttttgaaac
     5581 ttgataagag aagccactgt ctttactaaa aagtaaaggc tgcgataaag gacagtgact
     5641 ttaataaagt tgcactgttg tattgtcttt ggataaaatt gtctaaaggg aagttttatc
     5701 cccaacgaaa aaacatctaa agtggtaagt aatgaaagaa tgtcgataaa gtaggaatgg
     5761 gggatctttt tgaatacaat agaatcacag tttgataagg ttgcagaaga ttacgatttc
     5821 gtgaatgagc ttttgaatga ttattcattc tttgtgtcta atatgtctcc aaagaaaggc
     5881 agagcattag atatcggatg tggctcgggt ttgttagtgg agaaattagc aagttattat
     5941 gatgaagtgg tagggattga tatttctaat caaatgctcg atcttgccaa atctaaacgt
     6001 caactaacaa atacggtcta tctgaatatg aatgcagaac aacttaattt taatgagaag
     6061 tttgatttta ttgtaagccg aacaaccttt catcatttgg atgatatagc cagcgtaata
     6121 cagcaaatga aggaactgtt gaatgaggaa ggaagaatag ttattcttga taatgtatct
     6181 gaagtcgaga caccgcctac ctatgtttat aaattagggg caatccaaga gtttttaccg
     6241 cattgtttca aatttggaat aaaaaatgcg attagaattt ataatcacaa cacatctaaa
     6301 tcatggcttg agcatttagc ttcagataag tacctatctg aacaaaatta ttacgattta
     6361 tatgaaaagt tgttgcctgg atgccaattc cataaaatgg gttgggcaat gggggttgtc
     6421 tggacaaaat aacttaaagc tgtggctttg aaaagttgaa tttgtgattg ttttcagagc
     6481 tatcgggtgc tttagtataa ataacaatga ataaaaaatc agcctgtatc ttatgttact
     6541 attaagtaat ttaagataca ggttttacta tttttgaaat aagtaccttc cacttcaaat
     6601 acatgtattc aaagtgaaag tattgattta aatgattct
//
LOCUS       DAFELK010000096         6440 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFELK010000096
VERSION     DAFELK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.102"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            191..1180
                     /locus_tag="LP433_002725"
     CDS             191..1180
                     /locus_tag="LP433_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2006833.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1162..1623
                     /locus_tag="LP433_002726"
     CDS             1162..1623
                     /locus_tag="LP433_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2006834.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1673..2137
                     /locus_tag="LP433_002727"
     CDS             1673..2137
                     /locus_tag="LP433_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2006835.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2151..2900
                     /locus_tag="LP433_002728"
     CDS             2151..2900
                     /locus_tag="LP433_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2006836.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2900..3730
                     /locus_tag="LP433_002729"
     CDS             2900..3730
                     /locus_tag="LP433_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2006837.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3730..4377
                     /locus_tag="LP433_002730"
     CDS             3730..4377
                     /locus_tag="LP433_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2006838.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4475..5251)
                     /locus_tag="LP433_002731"
     CDS             complement(4475..5251)
                     /locus_tag="LP433_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2006839.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5395..6354
                     /locus_tag="LP433_002732"
     CDS             5395..6354
                     /locus_tag="LP433_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2006840.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
BASE COUNT         2215 a          933 c         1160 g         2132 t
ORIGIN      
        1 gttttcataa atctattata aaagaaaaga ctgtagacat catccataaa atggactttg
       61 tctacagtct ggcattttat tatataaaat tgttataaaa aaattttttt gaaaaatagt
      121 attgcaaaat aaagcaattt catagataat aggtattgta aagttatatg actttataat
      181 acttattaga gtgagggata aagaaatgag acaactacac aaagaacaga ttgaaacagc
      241 aatggcagcg ttaaaggaaa agacaattga tcatgtatat tttacagcat gtgggggttc
      301 acaagccgtt ttaatggctg gtcaatatct atttgataaa gaattaactg taccttgtca
      361 tgtttatact gctaacgaat ttaactatgc tataccaaaa ggattatctg aaaattcttt
      421 agttatcact tgttcccatt ctggcacaac accagaaact gtagaagcaa caaaaaaagc
      481 aagagaattt ggagcaatga ctatttgttt atctaatgaa gaaggatctc ctctatggga
      541 agcagctgaa tatcctgttc actatgattg gggtaaagat gttgatgcta gtgatttaaa
      601 taaaggaatt ctttatggtt tattatttaa tattttactt gttttagatg gctctaaaaa
      661 atgggaaact tgcttgaatg aatttgataa gttaaatgat cttgttattg ctgaaaagag
      721 caaatttgaa ataactgcta aagaatgggg taaaaaccaa aaacgagata aaattattta
      781 cacaattggt agcggtatca attacggaga aatttactcc acagcagctt gctggttcat
      841 ggaaatgcaa tggattaatt ctaatgctat tcattctggg gaatttttcc atggtccttt
      901 tgaaatcact gattatgatg taccattcat cttagtgaaa agtattggag atacaagatt
      961 tttagatcaa cgggtagaag acttcactaa aaaattcagt aataaattaa tggttttaga
     1021 ccaagctgat tttgacttag aatctataga tagtgtagcg aaagaatata ttgcagctgt
     1081 acttagtggc gttgttattc gccaaatggt agaagcgatt gcttttgaaa gaggccattc
     1141 cttagatgtt agacgctata tgtggcaaat gaaatattaa ttaataggag gttgcaaaag
     1201 atggcaaatc aattatttca cattgtgatt acaacacatt ctaccctttg tgagggttat
     1261 ttaaaggcaa caaaattaat tttaatgaat gacgccacag gtattagtgc tgttccattt
     1321 aaagaaaata ctagtccaga tgattttgag gagagtatga aagaaataat tagtcagcat
     1381 catttgcaac ctctaattat tttaacggat ttaattggag gaacacctaa taatgtttct
     1441 attaaacagt tgaacaacaa tagaattcaa attattgctg ggattaattt acctctttta
     1501 ctggagttat taatggccca gtcagctggt aaatctatag aagaaataga ttttaaggaa
     1561 ttactgaata actctcaaaa aagtatggtt catattaatt cgcttttaaa agatgtcagt
     1621 taaggtggca atttctattc tataaatttt aaaaattgaa ggaggaaata gaatgattaa
     1681 attagtgcgt gtagaccaca gattacttca tggacaagta atattttctt ggactaaaca
     1741 gtatgatatt aaccatatta ttgtggctga taacaaagtt ccaggagatc caatgtctgt
     1801 gatggctttg acaattgcta aacctgctga ttgcaaatta gacattgtta aaattagtga
     1861 tgttaaaggg attatggaaa catccccaaa tgataattac atgattttaa ttaaaggacc
     1921 taaggaagct tttgaattag ttcaaaattt accagaaatt aaagaaatta attttggcgg
     1981 tgtgtctaag aaaagcgagt ccaaacaata tggaaaggca gtctttttaa ctcctgaaga
     2041 attagaagcc acaaaaaaaa ttcttgatca agaagtgaaa atatttgtgc aacaagtccc
     2101 atcttcaagt attgaaaatg tagattttag taagtaaggg gggaaaataa atgttattaa
     2161 aagccatttt attaggttta gttggtgtgg tagctgttat tgactccagg ttaattggtc
     2221 gacaaaatat tggtagacca ctaattttga gtacacttgc cggacttgtg ctaggtgact
     2281 tgcatacagg gattgttctt ggggcatctt tagaattaat ttctatggga ttcgtctcaa
     2341 ttggggcggc tggacctcct aatatgcaac ttggtagtat tattgccact gcttttgcaa
     2401 ttttaactaa tagtagtaca gaaacagcct taacaatagc tatcccagtg gctgtagctg
     2461 gtgaatttat gagtattatc atgcgcatga taattgctca atttggacat gctgcagata
     2521 aagccattga aaataataaa tttagaaaag ctcaaattat tcatatttat tggtcattta
     2581 tttttaatgc ttttgtttac tttattccaa tctttttaac agtatatttt ggtgctgacg
     2641 ttgtggcaga tttagtagat aaaattccag aaatgattac agacgccttg actgtctctg
     2701 gaaatatgct ttccgcatta gggtttgcaa tgctattaag cacaatgttg agtaaaaaat
     2761 tatatcctta ctttattttt ggattcttta ttgttgccta ttcaggtctt tcactaattg
     2821 gcgtgacaat ttttgcagct ctgattgcct ttgtaatgga tcaagttaaa tatggaaaaa
     2881 gagaagaggc gcatggttaa tggaaaatag tacagaaaaa aaacgtttaa tcacaaaaaa
     2941 agatcttaat aagatgtgtc ttcgttcatg gacaatcatg tgttcgtgga attatgaaag
     3001 acaaatgcat atgggattta tgtatgggat ggcgccaatt ttaaataaag tttataaaaa
     3061 tgatgaagag aaaaaaagag aagcttatac tcgtcatatg gcatttttta actgtacgcc
     3121 tcaaatgact tcatttatta tgggactttg tgcttctatg gaagaacaaa atgctcaagc
     3181 agaagaagga aactttaata ctgaatctat ctccatgatt aaaaccagtt taatgggtcc
     3241 ttttgctgga attggtgatt catttttcca aggtacttta agaattatta catttgggat
     3301 tggattgtct tttgctaagc aaggtagtat tttaggaccg attttagctg ttggcctttt
     3361 tgctatacct tctattttag ctgtttttta cggcggtaaa ttaggatatg agtctggcaa
     3421 taaatacctt actaaattgt atcaagaagg tcttatggat cgagtaatgc aatttgcttc
     3481 tatcattggt ttggctgtag taggtggaat ggtggctagc atggtgccaa ttgtcacccc
     3541 tttaaaattc actacagggg gaacagaact tgttttacaa gacttacttg attccattat
     3601 tcctggatta ttaccacttg tatgtacttt gggaatatat aaattgatta agaaaaatgt
     3661 tagtacaaat atgctcttat taggttgtat tttggcaggg tttgttttaa gtataatagg
     3721 tatcttataa tgattaaggc tctaattttt gatatggacg gagttttaat tgatagcgag
     3781 attatgtatc aaaagtgggt atttaatttt ttaaaacaag aaaatttaag ctatcctttg
     3841 tattcttatc aaaaaaagat tggaactaca gcaagtattt ttgatgatat agaaaagtac
     3901 aatgagggat gtaacagttt agaattgaag ggaaaattta ctaaatattg gaaatcgcaa
     3961 aagattgatt acttggatat ttttcctaat atactaattg aacagcttga atggttaaaa
     4021 aagaaaaaaa taaaaatggc aattgcttct tccagtccaa tggatactat aaatgaagtt
     4081 gttaccactt gtaaaataga gtcatatttt gattgtttaa ttagcggaag agatttgcca
     4141 gaaagtaaac ctaatcctac tatattcctt aaagcttcag aacagctcag aattccagtt
     4201 gaagaatgtc tggtgataga agattcttat aatggtataa aagctggtaa aagagcaaat
     4261 atgaaggttc ttgcaattaa agataaacgt ttttctcaag atgtaagtct agcagatgat
     4321 gttatttacg atattaaata tctgcgacaa gaagtacagg tgaaatttgg aatataaata
     4381 agttttttga tgtatttaga gaatattagt aaaaataaaa atcatgccca aatctaatca
     4441 aaattgattg ctttgggtat gatttctttt aatatcaatc tattacttta ggatctgaat
     4501 catttttatg caccgtatct aaagtgatat tttctgtgac ttcaataaca taactaattc
     4561 tatcacaacg aactgtggat tgagaataat gaaatggttg attattttta tctttgccaa
     4621 ccttttctaa aataaatagc ggatctccta ctatacattg caataagtcg gaaagctcag
     4681 gtgttgcaga taaaccgttt atttccataa tagagctcgt agctttgaca tcatagtcat
     4741 cttctagaag tttatataat gaagtatatt ggctaccttt ttcaaataaa gttggaaatt
     4801 tttcttctga tgcgaaaaaa ttatcaattc ccatcggggc accgtcttcc cacattaaac
     4861 gtttaatatt gtaaactcta tcagttacat tgatttgtaa tttattagct aaaaactcat
     4921 cagcctttat aattttagaa tgtaaaacag tatatctaat tttatgtcct cgggtagaaa
     4981 gagaatcgct aaatccatga actccagcta attttaaact ttcttttttt tgagttacaa
     5041 aggtcccttt cccccttaat cgttcaactg ttccactttc tgctaaaagt ttaaaagctt
     5101 ttcgaatggt aatcttactt actccataaa ttttacataa ttcttcttct gtaggtaatt
     5161 gctctcctgg aagatatttt ttttcacgaa tatcgttacg tatagaagct tctacttgta
     5221 aatataatgg tctattatct tgaaaattca tagtacactc cctaaaaagt tatacttcat
     5281 tatatcacaa tttattaaaa cgtcgattgt aaaattaagc tagacaacta aaaagatcat
     5341 ttgtgctaca ctcaaaatag ttccgaccaa agaattaata aggagtgagt acaaatgact
     5401 tacacccatc ttacaacaga cgaactagta atcatagagt cttatttcaa tatcgagaaa
     5461 cctgtcgctc ttgtcgcaca aagtttaaat cgctctagac aaaccattta taatgtttat
     5521 tcgtttctca aacaaggaaa aaaagtgcta gattattacc gtcaatacaa acaaaataaa
     5581 tctcgttgtg gacgacgttc aaccgtttta tctgatgaac aatcaacata tgttcaagaa
     5641 aaggtagctc aaggatggtc acccgatgtg attatcggcc gtggcgagtt tccaattgat
     5701 tgttctgttc gtacactcta tcggatgttt aaaaaaggcc tttttgacac acagtcgtta
     5761 cctatgaagg ggaaacgtaa accgaataat catcaagaaa agcgtggaaa acaggccttt
     5821 cgcagaacga ttcatgaacg gaacagtctc tatccacacc tgactaaaga atttggtcat
     5881 ctcgaagtcg acaccattgt gggagttaaa cacaagagcg ctgttattac attggttgag
     5941 tgtttatcca aggttattat tactttgaaa ccgacaggca gacgagccga agatatcgaa
     6001 aacaggttaa atgattggtt caaatccatg cctaaacact tgtttaaatc catgacattt
     6061 gattgtggaa aagaattttc caactggcga tctataagta actcgaacga tattgccatc
     6121 tttttcgcag atccaggaac accttcgcaa agagggctaa atgagcactc aaacggcttg
     6181 cttagacgag atggcttacc taaaacaatg gactttaggg acacggatga aacctttatt
     6241 caatccgttg cctcgaaaag aaaccatatt ccaagaaaat cattaaatta tcgaacacca
     6301 ttggaagtat ttttgagctg catagataaa gacatattgt ctagcttaat ttgacaaatc
     6361 agaaaaacta aaaatgtaag ggaacccatt gaatttaacc aaattttttt aattttgcaa
     6421 aaaaaagtta aagaagactg
//
LOCUS       DAFELK010000097         6173 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFELK010000097
VERSION     DAFELK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.103"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            725..811
                     /locus_tag="LP433_002733"
     CDS             725..811
                     /locus_tag="LP433_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL2006841.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="LP433_002734"
     CDS             complement(932..1621)
                     /locus_tag="LP433_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006842.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="LP433_002735"
     CDS             complement(1866..2780)
                     /locus_tag="LP433_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL2006843.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="LP433_002736"
     CDS             complement(2762..3142)
                     /locus_tag="LP433_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBL2006844.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="LP433_002737"
     CDS             complement(3592..3879)
                     /locus_tag="LP433_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2006845.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="LP433_002738"
     CDS             complement(3899..4123)
                     /locus_tag="LP433_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBL2006846.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="LP433_002739"
     CDS             complement(4578..4748)
                     /locus_tag="LP433_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006847.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="LP433_002740"
     CDS             complement(4763..5296)
                     /locus_tag="LP433_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL2006848.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="LP433_002741"
     CDS             complement(5317..6159)
                     /locus_tag="LP433_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2006849.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1634 a         1153 c         1041 g         2345 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaacaaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtacatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAFELK010000098         5899 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFELK010000098
VERSION     DAFELK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.105"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..166
                     /locus_tag="LP433_002742"
     CDS             <1..166
                     /locus_tag="LP433_002742"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL2006850.1"
                     /translation="GTLKVEMFNLDTFDRPAYLDRKIKAYIAFFNNERVTLDMGLAIP
                     TEEKILQMIA"
     gene            complement(251..3175)
                     /locus_tag="LP433_002743"
     CDS             complement(251..3175)
                     /locus_tag="LP433_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBL2006851.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            3321..3896
                     /locus_tag="LP433_002744"
     CDS             3321..3896
                     /locus_tag="LP433_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006852.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            4110..4805
                     /gene="vanR"
                     /locus_tag="LP433_002745"
     CDS             4110..4805
                     /gene="vanR"
                     /locus_tag="LP433_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL2006853.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4783..>5899
                     /locus_tag="LP433_002746"
     CDS             4783..>5899
                     /locus_tag="LP433_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2006854.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVEL"
BASE COUNT         1823 a         1119 c         1121 g         1836 t
ORIGIN      
        1 gggtaccctc aaggtggaga tgtttaacct ggatacgttt gacagaccag cgtacttaga
       61 ccggaaaatc aaggcataca tcgcgttctt caacaatgaa cgcgttactt tggatatggg
      121 attagcaatt cctacggaag agaagattct acaaatgatt gcataaacgc tacaaaaaaa
      181 gaccacacat ttttacatgc atggtctaaa atactttgtt tttttacctg tctacttgac
      241 agggggcagt tcactctgag ttaaaatggt attctcctag taaattaata tgttcccaac
      301 ctaagggcga catatggtgt aacaaatctt cattaaagct acctgtccgt tttttatatt
      361 caactgctgt tgttaggtgg agagtattcc aaatacttat agcattgata attatgttta
      421 aagcactggc tctttgcaat tgatgctgta tggtgcgttc tctaagctca ccttgttttc
      481 cgaagaaaat agctcttgcc aatccattca tggcttctcc tttattcaat cctctttgta
      541 tttttcttct taatgattca tccgatatat aattcaaaat aaagatcgtt ttttctattc
      601 ggcccatctc acgtaaggct gtagctaagc tgttttgtct tgaataggaa cctagcttcc
      661 ccataataag ggatgctgaa actgttccct cccttataga atgagctaat cgcaaaacat
      721 cctcataatt ttctttaatg acctttgtat ttatttgtcc acgtaaaatg gcttctagtt
      781 ttggatactc acttgcttta tctatcgtaa ataattttga gtccgataaa tcccttattc
      841 ttggggcaaa tttaaatcct aataaatgag tcagtccgaa tatttggtca gtgtaaccgg
      901 cagtgtctgt ataatgttcc tctatgttta gatccgtctc atgatgtaac aaaccatcca
      961 aaacatgaat cgcatctctt gaattagtat gaataatctt tgtgtagtaa gaagagaatt
     1021 gatcacttgt aaatcggtag atggtggctc cttttccagt tccataatgt ggatttgcat
     1081 ctgcatgtag tgatgaaaca cctagctgca ttctcatacc atctgacgaa gatgttgtac
     1141 cgtcgcccca atagaaaggc aattgtaatt tatgatgaaa gtttactaat atggcttggg
     1201 ctttattcat ggcatcttca tacatgcgcc attgagatac attggctagt tgcttatatg
     1261 taagtccggg tgtggcttcg gccatcttgc tcaagccaat attcattccc attcctaaaa
     1321 gggcagccat gataatgatt gtttcttcct tatctggttt tcgattattg gaagcatgag
     1381 tgaattgctc atgaaatcct gttatatggg ccacatccat gagtaaatca gttaatttta
     1441 ttcttggtag catctgataa aggcttgcac taaatttttt tgcttcttct ggaacatctt
     1501 tttctaagcg tgcaagtgat agctttcctt tttcaagaga aaccccatct aacttattgg
     1561 aattggcagc taaccacttt aacctttcat taaagctgct ggttctctcc gttatataat
     1621 cttcgaatga taaactaact gataatctcg tattcccctt cgattgattc catgtatctt
     1681 ccgaaaacaa atattcctca aaatccctat attgtctgct gccaacaatg gaaacatctc
     1741 ctgcccgaac atgctcccga agttctgtta aaacagccat ttcatagtaa tgacgattaa
     1801 ttgttgtacc atcatcctcg tataaatgtc ttttccatcg ttttgaaata aaatccacag
     1861 gtgagtcatc aggcactttt cgctttccag attcgttcat tcctcggata atctcaacag
     1921 cttgtaaaag tggctcattt gcctttgtag aatgaaattc caatactctt aatagcgttg
     1981 gcgtatattt tcttagtgaa taaaaccgtt tttgcagtaa gtctaaataa tcatagtcgg
     2041 caggacgtgc aagttcctga gcctcttcta ctgaagagac aaaggtattc cattcaataa
     2101 ccgattctaa aaccttaaaa acgtctaatt tttcctctct tgctttaatt aatgcttgtc
     2161 cgatgttcgt aaagtgtata actttctcat ttagcttttt accgttttgt ttctggattt
     2221 cctcttgagc cttacgacct tttgataaca aactaagtat ttgcctatca tgaatttcaa
     2281 acgctttatc cgttagctcc tgagtaagtt gtaataaata gatggttaat atcgaataac
     2341 gtttattttc ttgaaagtca cggaatgcat acggctcgta tcttgagcct aagcgagaca
     2401 gctgcaacag gcggttacgg tgcaaatgac taatttgcac tgtttctaaa tccattcctc
     2461 gtatgtattc gagtcgttct attattttta gaaaagtttc gggtgaagga tgacccggtg
     2521 gctcttttaa ccaacccaat atcgttttat tggattcgga tggatgctgc gaggtaataa
     2581 tcccttcaag cttttctttt tgctcatttg ttagagattt actaaccgta ttaaatagct
     2641 tcttttcagc cattgccctt gcttcccaca ccattctttc aagtgtagtg atagcaggca
     2701 gtataatttt gttttttctt agaaaatcta tgcattcatg cagtagatga atggcatcac
     2761 cattttccaa agctaattga tgaaggtact taaatgtcat tcgatattca ctcagggtaa
     2821 aagttacaaa gtcgtattca cttcgaattt ctttcaaatg atcccaaagt gtattttccc
     2881 tttgaggata atgatcaagc gaggatggac taacaccaat ctgtttcgat atatattgta
     2941 tgaccgaatc tgggatgctt ttgatatgag tgtatggcca accgggatac cgaagaacag
     3001 ctaattgaac agcaaatcct aaacggtttt cttccctcct tcgcttatta actatttcta
     3061 aatcccgttt ggaaaaagtg aagtaggtcc ccagtatcca ttcatcttca gggatttgca
     3121 taaaagcctg tctctgttcc ggtgtaagca attctctacc tctcgcaatt ttcattcagt
     3181 atcattccat ttctgtattt tcaatttatt agttcaatta tatatcaata gagtgtactc
     3241 tattgataca aatgtagtag actgataaaa tcatagttaa gagcgtctca taagacttgt
     3301 ctcaaaaatg aggtgatatt ttgcggaaaa tcggttatat tcgtgtcagt tcgactaacc
     3361 agaatccttc aagacaattt cagcagttga acgagatcgg aatggatatt atatatgaag
     3421 agaaagtttc aggagcaaca aaggatcgcg agcaacttca aaaagtgtta gacgatttac
     3481 aggaagatga catcatttat gttacagact taactcgaat cactcgtagt acacaagatc
     3541 tatttgaatt aatcgataac atacgagata aaaaggcaag tttaaaatca ctaaaagata
     3601 catggcttga tttatcagaa gataatccat acagccaatt cttaattact gtaatggctg
     3661 gtgttaacca attagagcga gatcttattc ggatgagaca acgtgaaggg attgaattgg
     3721 ctaagaaaga aggaaagttt aaaggtcgat taaagaagta tcataaaaat cacgcaggaa
     3781 tgaattatgc ggtaaagcta tataaagaag gaaatatgac tgtaaatcaa atttgtgaaa
     3841 ttactaatgt atctagggct tcattataca ggaaattatc agaagtgaat aattagccat
     3901 tctgtattcc gctaatgggc aatattttta aagaagaaaa ggaaactata aaatattaac
     3961 agcctcctag cgatgccgaa aagccctttg ataaaaaaag aatcatcatc ttaagaaatt
     4021 cttagtcatt tattatgtaa atgcttataa attcggccct ataatctgat aaattattaa
     4081 gggcaaactt atgtgaaagg gtgataacta tgagcgataa aatacttatt gtggatgatg
     4141 aacatgaaat tgccgatttg gttgaattat acttaaaaaa cgagaattat acggttttca
     4201 aatactatac cgccaaagaa gcattggaat gtatagacaa gtctgagatt gaccttgcca
     4261 tattggacat catgcttccc ggcacaagcg gccttactat ctgtcaaaaa ataagggaca
     4321 agcacaccta tccgattatc atgctgaccg ggaaagatac agaggtagat aaaattacag
     4381 ggttaacaat cggcgcggat gattatataa cgaagccctt tcgcccactg gagttaattg
     4441 ctcgggtaaa ggcccagttg cgccgataca aaaaattcag tggagtaaag gagcagaacg
     4501 aaaatgttat cgtccactcc ggccttgtca ttaatgttaa cacccatgag tgttatctga
     4561 acgagaagca gttatccctt actcccaccg agttttcaat actgcgaatc ctctgtgaaa
     4621 acaaggggaa tgtggttagc tccgagctgc tatttcatga gatatggggc gacgaatatt
     4681 tcagcaagag caacaacacc atcaccgtgc atatccggca tttgcgcgaa aaaatgaacg
     4741 acaccattga taatccgaaa tatataaaaa cggtatgggg ggttggttat aaaattgaaa
     4801 aataaaaaaa acgactattc caaactagaa cgaaaacttt acatgtatat cgttgcaatt
     4861 gttgtggtag caattgtatt cgtgttgtat attcgttcaa tgatccgagg gaaacttggg
     4921 gattggatct taagtatttt ggaaaacaaa tatgacttaa atcacctgga cgcgatgaaa
     4981 ttatatcaat attccatacg gaacaatata gatatcttta tttatgtggc gattgtcatt
     5041 agtattctta ttctatgtcg cgtcatgctt tcaaaattcg caaaatactt tgacgagata
     5101 aataccggca ttgatgtact tattcagaac gaagataaac aaattgagct ttctgcggaa
     5161 atggatgtta tggaacaaaa gctcaacaca ttaaaacgga ctctggaaaa gcgagagcag
     5221 gatgcaaagc tggccgaaca aagaaaaaat gacgttgtta tgtacttggc gcacgatatt
     5281 aaaacgcccc ttacatccat tatcggttat ttgagcctgc ttgacgaggc tccagacatg
     5341 ccggtagatc aaaaggcaaa gtatgtgcat atcacgttgg acaaagcgta tcgactcgaa
     5401 cagctaatcg acgagttttt tgagattaca cggtataacc tacaaacgat aacgctaaca
     5461 aaaacgcaca tagacctata ctatatgctg gtgcagatga ccgatgaatt ttatcctcag
     5521 ctttccgcac atggaaaaca ggcggttatt cacgcccccg aggatctgac cgtgtccggc
     5581 gaccctgata aactcgcgag agtctttaac aacattttga aaaacgccgc tgcatacagt
     5641 gaggataaca gcatcattga cattaccgcg ggcctctccg gggatgtggt gtcaatcgaa
     5701 ttcaagaaca ctggaagcat cccaaaagat aagctagctg ccatatttga aaagttctat
     5761 aggctggaca atgctcgttc ttccgatacg ggtggcgcgg gacttggatt ggcgattgca
     5821 aaagaaatta ttgttcagca tggagggcag atttacgcgg aaagcaatga taactatacg
     5881 acgtttaggg tagagcttc
//
LOCUS       DAFELK010000099         5862 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFELK010000099
VERSION     DAFELK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.106"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            212..1438
                     /locus_tag="LP433_002747"
     CDS             212..1438
                     /locus_tag="LP433_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006855.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            2288..3612
                     /locus_tag="LP433_002748"
                     /pseudo
     CDS             2288..3612
                     /locus_tag="LP433_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
     gene            3605..3952
                     /locus_tag="LP433_002749"
     CDS             3605..3952
                     /locus_tag="LP433_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006856.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            4267..5124
                     /locus_tag="LP433_002750"
     CDS             4267..5124
                     /locus_tag="LP433_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL2006857.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            5144..5704
                     /locus_tag="LP433_002751"
     CDS             5144..5704
                     /locus_tag="LP433_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HBL2006858.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
BASE COUNT         2260 a          747 c         1096 g         1759 t
ORIGIN      
        1 tttagttttg atgaagatga atttgaaaaa ttagtgatgg actggcgtaa gaatttactg
       61 gatacggtac aattctaaaa gcaattgagg tcgaaattcc gatacttgaa tcatgatcta
      121 tattatcgtg ttatgagtga aatttctaat aaagataaga tatttcattt ggacagtcat
      181 gtgaatatga gcttaacaat taaacgtatt tatgatcttt tatatgttta taaacattaa
      241 tgaggtgcta aaattgacaa caataactat gacaaaaaaa atagaagtat atgttgatgg
      301 atcacaagaa gaaagggatt ccttttttga ttttttttgg aaaaatagta gagaatatgt
      361 aaaagcgttg aatctggtat ataaacagct aatgtttgaa gagttgataa aagatgcaat
      421 taaagaaatg gatcaaggtt atgctgagag agaagaaagt attcaaaatc ggattgaaaa
      481 gttagcatat actgatccaa tagatcaaaa aaaacttgat aaagcaaaag ctgaattatc
      541 taaattgaga aatgaaaaaa ataaagaagc gagagaaata ttaacgcaag cgatagggtt
      601 gaagagtcaa acgagaacac gagatgtagc aaaaaaatta gactttgact ttggagattt
      661 tgttgattcc gcaaatatga aagctagtaa agattttggc aatgatttta tcggaattgt
      721 gaccggacaa agaacgccta gaatatataa aaatagaaac aaatatggat tactaccttt
      781 tagaggtcga gatattaaaa tccataaaga tgataagttt tatatttatt tacctaaagg
      841 ctttaggttt aaagtgaatt taggtagcaa gccaagaaaa gcaagagatg ttgcttcagt
      901 tttacaacac attatggatg gcgattacaa attaaatcaa agtaatctta tttttgatgg
      961 aagaaaatta ttttttaatc taacaatttc ttttgaaaaa agctataatg aaatggaatt
     1021 caagaaaggt aatgaattga tcgtaaactt tgcagatttg tgtagcggtg aatgtttaat
     1081 taatgataaa tctgtaatgt cttttggtga tagccaatat ataagaaact tcaaaagtaa
     1141 aattttagca atgaaatcaa aagaacaaag ccgaggagtc ttttctaagg gcggtcatgg
     1201 tcgaaaaaga aaattagatc aagatcgatg ggaagcaata aagaaaagag aaagtaattt
     1261 tgttaaaact tataataatc aatgttctgc aaaaatcgtt aaaactgcta ttcgcaataa
     1321 agctcaaatt attcgtatca ttgaaccaga taaggcttat ggcgaatggg cttactatca
     1381 attgaaagaa caactagtaa acaaaggaaa aagatatggg atagaagtca gaagttagta
     1441 aattaaacaa tcgttgattt ggcaacgaaa tagtgaggga aaatccactc actgaagggt
     1501 aaactccgtc aagttgtgtg accagacgga aggacgaatg ttgttgaggt tttagaacca
     1561 tataaaacag catgtttctc aaatttttag gataagggaa attgctagca gtttgtttta
     1621 gaaccatata aaacagcatg tttctcaaat gagtacttta aattaattga tggcgttcct
     1681 gctttagaac catataaaac aacatggatt taaaacaaga agtaagtcag ttctcctttt
     1741 actttagtaa ggaaaaataa agtattctca ataaaactta aaataagcaa acctttgttt
     1801 taatagctaa tcgaagtaaa acccaaagcc atatgaaccc ctgaatcagc gaaagtttat
     1861 gatgatttgg attactaata gtttaggaat tagatggtaa atctaaatta aacaatcgtt
     1921 gatttggcaa cgaaatagtg agggaaaatc cactcactga agggtaaact ccgtcaagtt
     1981 atgtgaccag acggaaggac gaatgttgtt gaggttttag aaccatataa aacagcatag
     2041 ttctcaaatt gtttaaaatg attgtcaagt taaaaaaatc tgggatcata taaaatagta
     2101 tagttctcaa atatgattag aaaccctatt aaagagcaat attaagccaa cttacttaaa
     2161 tcgtttaatt aagaacaata atctctttta gtcagacttt tagtctgact tttttgtatt
     2221 tccaaaattt attctttaca aaaacgaaca tacgtttgta taattgcttg tgaatggggg
     2281 aataaaaatg tttgattaca gtagagaacc ggtgaatgac tattttttaa tcgacatgaa
     2341 gtctttctat gctagcgtgg aatgtattga acgaaattta gacccaatga ctacaccgtt
     2401 aattgtcatg agtagatcgg acaacactgg ttcaggtctg actctagctt cttcacctac
     2461 tgcaaagaaa aaatatcata ttactaatgt tagtagagct actgatttac cttatccatt
     2521 accaaaagaa cttcatattg ttccaccacg aatgaactta tatataaaaa aaatatggaa
     2581 gttaatcaga tttttagaaa gtatgtcgca gatgaagatt tattgattta ttcgattgat
     2641 gaatcaattt taaaagtgac aaaatcctta aatttattta ctagttcagg aacaagaagc
     2701 gagagaagaa gagaattagc taaaataatc aaagatgaga ttcagaaaga aacaggtcta
     2761 atagcaacag tcggaatagg agataaccca ttattagcta aacttgcact ggacaatgaa
     2821 gcgaagagta gtaaagaatt tatagctgag tggacttatg agactgtacc tgaaaaaata
     2881 tggaaaataa acgagatgac tgacttttgg ggcattggat cacgcatgaa aaaaagattg
     2941 aatcatatgg gaattatgag tatagaagat ttagcaaatt ggaatcccta cacaattaaa
     3001 agtcagttag gtgtaatcgg actccagtta tatttccata ccaatggaat tgatcgtacg
     3061 gatattgcta ttccaccaga accaaccaaa gaaaagtctt atgggaattc acaagttcta
     3121 ccaaaagatt atacgaggag agaagaagta gaactagtag tcaaggagat ggcagagcaa
     3181 gtagccattc gaattagaca acacaattgc aaaactggtt gtgtacgctt agcaattggt
     3241 acgtcaattt tggaagaaaa atcaggtttc tcgcaccaga tgaaaatacc aattacagat
     3301 aatacgaaag aattacaaaa ttattgtctt tttttattca ataagtttta tgaggggcag
     3361 gaagtacgac atataggagt aacttatagc agattagtat acacagattc cctacaatta
     3421 gatttattta gtgatccaag aaaaaagatt gctgaagaaa atttggatag gattattgat
     3481 aagattagac aaaaatatgg atttacagct attatacatg cttcatctat gttagaaggt
     3541 gcaagaagta ttacgagaag cactttaata ggaggacacg caggaggatt aggaggtttg
     3601 cataatgatt gaatataacg atagaggacg tttaaaatgg tcgggatttt atttgtctga
     3661 tcatactgaa agaatcaatg cagacaatgt acaacgtgct aatcataatt tggcaaaaga
     3721 acaaatgacg actgaagaga ttgcgaaaat actgagaact gctgtcataa aaaatagacc
     3781 cgtctgcatt caaaaagagg aacgaaacgc tgaaggttac tatccagatg atgtagtagg
     3841 aaaaattatt ggatatgacg agcttggtgt atttgtggaa gaagaaaaag ttcactatga
     3901 tgaaattagg aatgtttctt tctcggaatt attaaaatgg agtcagatat gaacattatt
     3961 aaaaaatacg aattcggtta tattacgtat gaacagctaa tagaggaatt atggggatat
     4021 ggtcaacaat taattaatga agtggggatt gattgctttt gtttctatat tgaatccgga
     4081 gcaggatacc ataagaacag atactatata tttccatatc caccaaaata gtctcttaga
     4141 tatttttaaa ttttctccaa atactttcaa ttattgtgaa atatttccct ttaattaatc
     4201 aaatttttta taaaagtaat atataaaata aattgcttga agtattatat ttagatatca
     4261 taatttatgg aagaaaaatt aattaaaaag gatgagatta taatggggtt actggttccg
     4321 agagctaata cttatactat acctttaacg aaacgccaat taattgctaa aagatatcaa
     4381 aggattacta gagccatcaa tagagagttt tggaattctg aaagtgatac tgctcacagt
     4441 ttatacgtag gttcttatgg gagaggaacg gcaattagta ctagtgatat agatataata
     4501 gttgaattac cgatggcaga atttgacaga ttcaaaaatt atttatcaaa tggcccgtct
     4561 aagttattac aagttataaa aaacgcattt caggaaatac taccaaatag tgatattaga
     4621 gctgatggac aagttgttaa aataaatttc catgatggaa tcaaatttga aatagttcca
     4681 gcttttaatg aaaaagatta ttggggtgag tcaaaagggt ttatttatcc agattcaaac
     4741 atgggaggga actggaaagc tacaaatccc aaaaaagagc aagaagccat gaaattaaag
     4801 aatacaaaaa gtaataattt attatatgct acgtgtaaac attttcgaca tgtacgagat
     4861 acagaattta cgagttatca tctttcagga atagtaattg acagtttcgt atatgaggct
     4921 atgggaaatt ggaaattcgt tgaaaataac agtgggggtc aaaacattag ttctgtatct
     4981 tatgagacag ctttattaga atactataac tcacataaag ttatgggcgg tttaaattta
     5041 tactctcctg gaagcaatca atttgttaat tctgatagta gtatcatatg tttagaaaaa
     5101 gtattaaaaa aaatagcttt ataaagtttt atggaggaac aacatgggag acgaaaaaaa
     5161 gcgcttggaa gttcaattac gtgaagcata tggacgagta acgtatactt acaccactca
     5221 tttaaagcaa gccgataata ttatttctga caataaaatt ttaaggtgtc ttcaaattgg
     5281 tttgtcagcc cttactactg gaggggtact tagtaccatt attactgata atagtgagtt
     5341 aacctttgtt gctggattat gttcaacaat ttctcttgga ttaaacttat actttaagaa
     5401 ttttgatctt gctgaagaag ctaaaaatca tcaaattgtt gccgataaat tatggttgat
     5461 cagagaagaa tacgtaagct tactaacaga tttaaatcgt ttaagtgttg aagatattgt
     5521 gaaaaaaaga gatcaattaa tgaacgaaac tcatgaagca tataaaaatg cccctaaaac
     5581 aaatagtaaa agctatgaat cagctcagaa agcattaaaa tctgaagaag agcaattttt
     5641 tacagaagag gaattggata agatgttacc agagcatctt agaaaaaaga gttctaaata
     5701 ttgaactctt tttttatgct taaaattctc ttgtaatttt tctattcatc tatatttaag
     5761 aagaaatatg atgatagaaa catctcctaa agccaccgca agccgttcta agcatagctt
     5821 agcccgacat tgctagatat gctcatctca ccatgaacgt tt
//
LOCUS       DAFELK010000100         5614 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFELK010000100
VERSION     DAFELK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.108"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            67..150
                     /locus_tag="LP433_002752"
     CDS             67..150
                     /locus_tag="LP433_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBL2006859.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            275..1012
                     /gene="erm(B)"
                     /locus_tag="LP433_002753"
     CDS             275..1012
                     /gene="erm(B)"
                     /locus_tag="LP433_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL2006860.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1158..1442
                     /locus_tag="LP433_002754"
     CDS             1158..1442
                     /locus_tag="LP433_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBL2006861.1"
                     /translation="MPTKRSGPLVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFR
                     KKKLTKTNVKELLEGKENLVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            1605..2270
                     /locus_tag="LP433_002755"
                     /pseudo
     CDS             1605..2270
                     /locus_tag="LP433_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2306..2551
                     /locus_tag="LP433_002756"
     CDS             2306..2551
                     /locus_tag="LP433_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2006862.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2654..3523
                     /locus_tag="LP433_002757"
     CDS             2654..3523
                     /locus_tag="LP433_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL2006863.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3504..4238
                     /locus_tag="LP433_002758"
     CDS             3504..4238
                     /locus_tag="LP433_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2006864.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4271..5179
                     /locus_tag="LP433_002759"
     CDS             4271..5179
                     /locus_tag="LP433_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBL2006865.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5176..5574
                     /locus_tag="LP433_002760"
     CDS             5176..5574
                     /locus_tag="LP433_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2006866.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKGSVAKF"
BASE COUNT         2006 a          822 c         1132 g         1654 t
ORIGIN      
        1 gtgtataata ggaattgaag ttaaattaga tgctaaaaat ttgtaattaa gaaggaggga
       61 ttcgtcatgt tggtattcca aatgcgtaat gtagataaaa catctactgt tttgaaacag
      121 actaaaaaca gtgattacgc agataaataa atacgttaga ttaattccta ccagtgacta
      181 atcttatgac tttttaaaca gataactaaa attacaaaca aatcgtttaa cttctgtatt
      241 tatttacaga tgtaataact tcaggagtga ttacatgaac aaaaatataa aatattctca
      301 aaacttttta acgagtgaaa aagtactcaa ccaaataata aaacaattga atttaaaaga
      361 aaccgatacc gtttacgaaa ttggaacagg taaagggcat ttaacgacga aactggctaa
      421 aataagtaaa caggtaacgt ctattgaatt agacagtcat ctattcaact tatcgtcaga
      481 aaaattaaaa ctgaacattc gtgtcacttt aattcaccaa gatattctac agtttcaatt
      541 ccctaacaaa cagaggtata aaattgttgg gagtattcct taccatttaa gcacacaaat
      601 tattaaaaaa gtggtttttg aaagccatgc gtctgacatc tatctgattg ttgaagaagg
      661 attctacaag cgtaccttgg atattcaccg aacactaggg ttgctcttgc acactcaagt
      721 ctcgattcag caattgctta agctgccagc ggaatgcttt catcctaaac caaaagtaaa
      781 cagtgtctta ataaaactta cccgccatac cacagatgtt ccagataaat attggaagct
      841 atatacgtac tttgtttcaa aatgggtcaa tcgagaatat cgtcaactgt ttactaaaaa
      901 tcagtttcat caagcaatga aacacgccaa agtaaacaat ttaagtaccg ttacttatga
      961 gcaagtattg tctattttta atagttatct attatttaac gggaggaaat aattctatga
     1021 gtcgcttttt taaatttgga aagttacacg ttactaaagg gaatggagat aaattattag
     1081 atatactact gacagcttcc aagaagctaa agaggtccct agcgcctacg gggaatttgt
     1141 atcgataagg ggtacaaatt cccactaagc gctcgggacc ccttgtagga aaatgtccta
     1201 agtgtggcaa caatattgta ttaaaaaaat cgttttatgg ttgttcaaat tatcctgaat
     1261 gtaagtttac tttagctgaa cattttagaa agaaaaaact aaccaaaacg aatgtaaaag
     1321 aattactgga gggaaaagaa aacctggtaa aaggaatcaa aaacaaagag aaaaagccct
     1381 acaatgccgt tgtaaaaatt ggggaaaagg gatatattga ttttatctct ttttcaaaat
     1441 aaacatgggg ctgacccaaa agtagctcct atatgaaaaa tagaggtctt tccatttaga
     1501 tagtagtgga aagacctcta tttatctttt gaaagtgaat acaaaaataa agcacactct
     1561 gctataatat aggtgattaa tccatttgag agaggtgctt tatcatgtat caaaattata
     1621 ccataaacca actttgtttg cctatagatc ttgaaattaa attagaagaa aatgattttg
     1681 ctcatgccat tgtgcagttt gttgactcta ttcccgatga agtctttctt ccttattatc
     1741 aatctatggg tagaccccaa tatcatcctc gtatgctact ttccattatt ctttgtgcct
     1801 atattcaagg ggtttattcg ggccgccaaa tacaaaatat gctgatagat agtattcgga
     1861 tgcgctactt atctcaagag caattcccta actttcgtac tattaatcgt tttcgcgttc
     1921 atccgattat gaacgatatt ctagatcatt catttgttca atttcgtgag ctactggttc
     1981 aaagtggctt aatcagtggc agtgctctat acattgatgg tacaaaaatt gaagcggatg
     2041 cgaataaata ctctttcgtt tggaaaaaaa gtattttaaa gtataaggat agccttgatc
     2101 aaaaagccct tgaaaactac caacaaatgg tggaaacaaa aatcttacct gagttaatag
     2161 atgatttaaa ggatgaactt tctatagaag agattgaaag gattcgtcaa tctttggaag
     2221 aaaaggaaaa tcaattaatt gaagcgattg accaaaccga aacagtagaa gggggctgac
     2281 ccattattaa taaggagtgg acaacatgat tgatgtaaat gagctattgg aagaagctat
     2341 tagagaaact gaaaatctaa atgatggcga agtttttctt gttaaagatt tattcaaggg
     2401 atatgtgggg aataggatac ccagaaagga tcgacttctg cttggaacgt tatttttaaa
     2461 ccatgttagc aaaatgaatg gtaatttaaa ggctattgaa aagacttcat ctaatcagca
     2521 gaggtataaa aagacaattg ataagtttta actatctttt gtgaaattaa aaaaattata
     2581 aatatgttga gtagaagcaa aagatttggc ttggaatttt tacagcagtg aatcgataaa
     2641 aggagcatgc ttgatggtag ataatattat taaatcagta gcagagaaat tatcctctct
     2701 gtcttatata gaaggtattg ttttaggtgg ttcacgtgca aggggcaccc atacagagga
     2761 ttcggatata gatatcggca tctattacaa ttcagaatca tttgacataa atactattaa
     2821 tcaattcgct acaaagctgg atgatgagca tagaaataac cttgttgtac ctcccggagc
     2881 atggggtgat tggattaatg gcggcggatg gttagtcata aacgggtatc atgtggattt
     2941 aattttacgt gatattaaac gtgtggaaca aataatgaaa gatacagagc acggaattgt
     3001 tactgccaat tatcagactg ggcatcccca tggttatatt agtgcaatgt atcgaggaga
     3061 attagcgatt agcaaaatac tatatgctaa gaatgaaagc ttatgcgaat taaaaaaaca
     3121 ggcagaaact tatcccaatg ctttgcagaa aagtttagtt aactttttta tgtttgaagc
     3181 agggttctct ttaatgtttg taaaagcaaa ttcgggaaca gacgataaat attatattgc
     3241 gggtcatgtt tttcgtatag tttcatgttt aaatcaagtg ttatttgcat gtaataatgc
     3301 ttattgtatc aacgaaaaga aagctataaa actgcttgaa acttttgaac ataaacctga
     3361 aaaatatacc gagaaggtaa atcatatttt tgaagtactc ggtatctcac tttttgaatg
     3421 ctacgacatg accgagaagc tttataatga agtgaatgaa attgtatcgg agataaataa
     3481 ctttttaaac gaggagagtt cagatgaaag aaaacaaata tgatgataat atattttttc
     3541 aaaaatacag tcaaatgagt cgctcgcaga aaggactggc tggtgcggga gaatgggaga
     3601 ctttgaaaaa gatgctacct gattttaagg gtaagcgtgt gcttgattta ggatgcggct
     3661 atggatggca ctgtatatat gcgatggaaa acggtgcttc ctctgtagta ggtgttgata
     3721 tttctcataa aatgctcgaa gtagcaaaag gaaaaaccca ttttccacag attgaatatg
     3781 aatgctgtgc catagaagat gtggatttcc cagaggagag ctttgatgta atactaagtt
     3841 cgcttgcgtt tcattatgta gcagactatg agaatttaat aaaaaagata tataggatgc
     3901 tgaaggctgg tggcaattta gtttttacag ttgaacatcc tgtttttact gctcatggaa
     3961 cacaagactg gtattataac gaaaaaggag aaatactgca tttcccggtg gacaattatt
     4021 attatgaggg caaacggaca gctatgtttt tggaagaaaa ggttacaaaa tatcatagaa
     4081 cactgaccac atatctaaat acactgcttt caaatagttt tataataaat cagattgtgg
     4141 agccacagcc gccagagaac atgatggata ttccggggat ggcggatgaa atgcgacgcc
     4201 caatgatgct gattgtatcg gcaaaaaaga agatgtaata atatagaaaa aataaacgag
     4261 gagtatgtaa atgagatcag aaaaagaaat gatggattta gtactttctt tagcagaaca
     4321 ggatgaacgt attcgaattg tgacccttga ggggtcacgc gcaaatatta atatacctaa
     4381 agatgaattt caggattatg atattacata ttttgtaagt gatatagaac cgtttatatc
     4441 taatgatgac tggcttaatc aatttgggaa tataataatg atgcaaaagc cggaggatat
     4501 ggaattattc ccacctgaag aaaagggatt ttcctatctt atgctatttg atgattacaa
     4561 taaaattgat cttaccttat tgcccttgga agagttagat aattacctaa agggcgataa
     4621 attaataaag gttctaattg ataaagattg tagaattaaa agggacatag ttccgactga
     4681 tatagattat catgtaagaa agccaagcgc aagggagtat gatgattgct gcaatgaatt
     4741 ttggaatgta acaccttatg ttattaaagg attgtgccgt aaggaaattt tatttgctat
     4801 tgatcatttt aatcagattg ttcgccatga gctgctgaga atgatatcat ggaaggtcgg
     4861 catcgaaaca ggctttaaat taagtgtagg caagaactat aagtttattg aaaggtatat
     4921 atccgaggat ttgtgggaga aacttttgtc cacctaccgg atggattcct atgaaaacat
     4981 atgggaagca ttatttctat gccatcaatt gttcagggcg gtatccggtg aggtggcgga
     5041 aaggcttcat tatgcctatc cggagtatga taggaatata acaaaatata ccagggacat
     5101 gtataaaaaa tacactggta aaaccggctg cctggatagc acatatgccg ctgatataga
     5161 agagaggcgg gaacagtgat tacagaaatg aaagcagggc acctgaaaga tatcgataaa
     5221 cccagcgaac catttgaggt gataggtaag attataccga ggtatgaaaa cgagaattgg
     5281 acctttacag aattactcta tgaagcgcca tatttaaaaa gctaccaaga cgaagaggat
     5341 gaagaggatg aggaggcaga ttgccttgaa tatattgaca atactgataa gataatatat
     5401 ctttactacc aagacgataa atgcgtcgga aaagttaaac tgcgaaaaaa ttggaaccgg
     5461 tacgcttata tagaagatat cgccgtatgt aaggatttca gggggcaagg cataggcagc
     5521 gcgcttatca atatatctat agaatgggca aagggttctg ttgcaaagtt ttaaataaag
     5581 aataaaatcc cttacggtat ctatgattta agct
//
LOCUS       DAFELK010000101         5570 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFELK010000101
VERSION     DAFELK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.109"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(207..1169)
                     /locus_tag="LP433_002761"
     CDS             complement(207..1169)
                     /locus_tag="LP433_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2006867.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="LP433_002762"
     CDS             complement(1171..2610)
                     /locus_tag="LP433_002762"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBL2006868.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="LP433_002763"
     CDS             2795..4741
                     /locus_tag="LP433_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBL2006869.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..>5570
                     /locus_tag="LP433_002764"
     CDS             5005..>5570
                     /locus_tag="LP433_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2006870.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIE"
BASE COUNT         1775 a          956 c          957 g         1882 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa
//
LOCUS       DAFELK010000102         5516 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFELK010000102
VERSION     DAFELK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.110"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(78..444)
                     /gene="ssrA"
                     /locus_tag="LP433_002765"
     tmRNA           complement(78..444)
                     /gene="ssrA"
                     /locus_tag="LP433_002765"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(615..1388)
                     /locus_tag="LP433_002766"
     CDS             complement(615..1388)
                     /locus_tag="LP433_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2006871.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1532..1882
                     /locus_tag="LP433_002767"
     CDS             1532..1882
                     /locus_tag="LP433_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL2006872.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1863..2579
                     /locus_tag="LP433_002768"
     CDS             1863..2579
                     /locus_tag="LP433_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2006873.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2579..4027
                     /locus_tag="LP433_002769"
     CDS             2579..4027
                     /locus_tag="LP433_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2006874.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4097..4606)
                     /locus_tag="LP433_002770"
     CDS             complement(4097..4606)
                     /locus_tag="LP433_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006875.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4596..5321)
                     /locus_tag="LP433_002771"
     CDS             complement(4596..5321)
                     /locus_tag="LP433_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006876.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1872 a          964 c         1096 g         1584 t
ORIGIN      
        1 ttctctcctt gaccaaaata aaaaaacgtt gatttaacaa cgtttttcat acatgtttat
       61 ctgtctcaac catacatata tggagacggc gggagtcgaa cccgcgtcca aacacatcgc
      121 cacttaaaaa tctacgttca tagtcaactc atttaaggat tcactttaca gcttgccgag
      181 tgacaggcat tctgtatcgc tagtctgatg ttctcttttt caacttacag acggaaagtt
      241 gaaacgtatc ccactaaagt taggaccctt actcgagcac atgggcgatg ccgagaggat
      301 ctacgctaac tgtttttagg cagctaaagc gtaagagttg ttttcgtttt tagcagttat
      361 atttaactgt aacgttttta cgtagacgta acctacgaaa cgcaattcaa gctcgactgt
      421 gcctgtcgaa tccgtaacgt ccccgttagc taacaagggt tacgtgtatt tttcatacaa
      481 aattagtata gcatatattg ggataaattc aataaaaaag cgaatcatat cccattattt
      541 atataataac tgcccctttc ttaagaaaaa ataagcgatt ttcttaagaa aagaggtagc
      601 ttcaaaaaaa gatcttaaat cagatcaaaa tacttcaatg cgtggacaat tccgccttct
      661 gtatttttct ttgtgataaa ggtagaaagt tcttttaatc cgtcataggc gttgtccata
      721 gcgattttgt tgtcgcaagc ttccaacaag gcaaaatcat tcggaccatc gccaaatcca
      781 aaagtaggaa ctttttccag ctgaagttct ttttgcagac gtttgacacc tgcccctttt
      841 gagattcctt tcttcactgt atcgatcgag taaggaccat tccgataaaa agttagctca
      901 ggaaaatgtt cgtgatagta ttcgtcacct gattgagata agatcagcaa catatttact
      961 gtgttttctt taaagcctaa aggatcaatt tccggaacat ctgaatgaat gaagtcgtaa
     1021 gcattgatca ttgtttggct atgaccggta caccagattt tctgatcgtt atagtaagaa
     1081 agttcatgac cgttcaactg tacatgatca tacatttttt gacattcttc tgaagaaaat
     1141 gtttgagaat agatttcttc gccgtctact cgaatgaaag aaccattcat ggtgaccgca
     1201 gaagtaatgc ccgcatcttc catgatagag tggatttctg cttctgtacg tcctgtagcg
     1261 atgacgggga gaacattgtt ttcttttaat gcgttcatag cttttgccac ttcgggtgtg
     1321 atttttgatt tcgcatctag taatgttcca tcaagatcaa agaaagtgat tgcacgataa
     1381 tttgacacaa ataaaactcc ttttttattg gaataagttt atcttaacaa agaatgaaca
     1441 aaagacaaac ctttcgtgaa gaattcctga acatattggt tcagtcaaca atttagagta
     1501 tactataaga agagaattta ggagggaaag aatgattttt ttcagtattg gtatcttatt
     1561 cttaataatt ggcagtcttt ttcggattct gccctcaaaa ggaaatctgc ctttttatgg
     1621 gtatcattcg cctcttgccg caaaaacaga cgctcattgg cggctggctc aaaagacaag
     1681 cggaaactgg ttttttctta tgggcttact gatggcattg atcggctatt atttaaagac
     1741 atctgggcat acgaattatt ttctgattga aatgcttctg ctagtatttc caattatgcc
     1801 tatttttatt atgacagaaa agaaattaca gaaatatgac ctggaaactg gagggaacga
     1861 taatgaatat tttaatgatt gaagataatc aatctgtttc tgaaatgatg cagatgtttt
     1921 tcttaaatga aggttgggaa gcaactttca agtatgatgg aaaagaaggg ctcgatgcct
     1981 ttttagaaaa cccacaacat tgggatatga ttacactaga cctgaatttg cccacactgg
     2041 acggtatgct agtaggaaga gagatccgca aagtttcaag tactgtgccg attatcatgc
     2101 tgacagctag agattctgaa agcgatcagg tgatcggctt agagatgggg gcagatgatt
     2161 atgtcacaaa acctttcagt cctctgacgc ttattgctcg aatgaaagct ttgcatcgcc
     2221 gtagtgagtt ggcagaagca agagaagaag cagcagtttc agatgatcat tttgatatcg
     2281 agactagtca tttcaagatg aatacgaaaa cacgagaagc gtatctggac aaccggccaa
     2341 ttgaaggact gacgcctaaa gagttcgatc tattgtttac tttagcaaaa aaaccacgtc
     2401 aagtattctc tcgggagcag ttgcttgaat tagtctggga ttatcagtac tttggtgatg
     2461 aacggacagt ggacgcccat atcaagaaat tacgacaaaa aatcgaaaag gtcggaccac
     2521 aagtcatcca aactgtttgg ggagtcggct acaaattcga tgattctggt gttgcctaat
     2581 gcgttatttg tatcagcaac tcttagcttt ttgcggaatg gtcgcgttga tcttattgat
     2641 cgttggagtt tcttttacac aactgacaaa acaaacgatt gaagaaaaca attaccagca
     2701 actgtttgga tatgctgaat cagttgaaaa gacaacgcaa acctatgccg atacgctccc
     2761 gcagtttagt caagatcagg cgtttcaaaa tgcattgctg ctgacagagc aagtactgac
     2821 agaacaaaat gtgaacttta tatttatcga taaaaacgaa cgtgtcattt atccgactaa
     2881 tacagcttta ctgaatttta ccttaacagc tgatcaatgg aaaaatctga ggaatggacg
     2941 tcaagaaaaa ttcacatcga ataaaaatat tttaggacaa gcacaggcga cctcttacgc
     3001 acttgtgcca tttaatttga atcatgaatt ctatggagca cttgtagtta gtcaacctgc
     3061 gcgaaatatc gataacagcg ttcgtccaat tacactgaac ctgttcaaag gatttatttt
     3121 ttccagtatc gttgcagtta ttgccagcta tgcttttgca gcattccaag ttaagcgtat
     3181 caatcggtta aggaatgcga cgaaagaagt gacgaatggt aattttgatg tacagctccc
     3241 cgtacatgac aaagatgaat ttgatgagtt agcagatgat ttcaataaaa tgacgaattc
     3301 attgaaagaa tctcaagcag aaattgaaga acaagaaaat cgtcgaagac aatttatggc
     3361 agatgcttct cacgagatga gaacacctct tacgacaatc aacggacttc tggaagggtt
     3421 agaatacaat gcaatccctg aaaatcagcg agaaaacgcg attaaattga tgaaaaatga
     3481 aacagagcgt ctgatccgtt tggtgaatga aaacttggat tatgaaaaaa tccgtacgaa
     3541 tcaaatcagt atggtcatta aaaaattcaa tggaacagaa acattgaaaa atattgttgc
     3601 acagttagaa gctaaagcag aagcagcagg agatacattg acattgaaag ccgttgatga
     3661 tattgatgtt tacgctgatt atgaccgatt tgtccaaatc atggtcaata ttattcaaaa
     3721 cgcgatacag tttactgaaa acggccaaat cacgattact ttagaaaaag gctatcttga
     3781 aacgatcatc acgattgaag atacgggaat tggaatgtct gaacaacaaa tgaaaagtat
     3841 ctgggatcgt tattataaag tagatccttc aagaaaaaat acaaaatatg gtgaatcagg
     3901 attaggttta ccaatcgtgc agcaacttgt acgcttgcat aaaggaaaat tagaagtaga
     3961 aagcgaacta ggaaaaggaa caaaattcgc tgttcgtttg cctgacgtag aaatcaaaaa
     4021 agagtaaaaa acaagcggta taaaagatca tgaatcgatc ttctataccg cttgttttta
     4081 ctataaaatg attgatttag cccgcgggct ctaaacgatc aatataagga ctttgagcaa
     4141 tagtagcatc atgagtaaag agtaagatac cttgattttc ttcatgagct aaataagaaa
     4201 gcaagtggag tagctcttgg atctccaata cactaagttc atcaaatgta tcttcaataa
     4261 caatattgtt tcgcttggaa agcaaggcat gaagtaattg cagctttact ttttcaaaag
     4321 acgtcaactc agctgccgca caattaagca aggaaggaga gatatcaagt ttttcttgat
     4381 aggccaaacg atcttgtttg atttcttttt ccggtacatc caacaggaca tggtctttaa
     4441 gattcagata aggaaacatc ggccaatttt tttggatgat cgcaaaatta tccagttttg
     4501 caacaagaac ctcttttttc aagtgctcca atattttatg ctgtttttcg agaggacaca
     4561 aaataacggt caagtgttca gcatgaatca aatattcagg tttcattacg tccaggcctc
     4621 ctactttgca aatgatggat aaaaaaagtg aaagggaata gactaagaat gagacagcat
     4681 ccactgagcc caataagagt ttgggcaaat cccttaagta tatctgtgaa aaaaagatca
     4741 ttttggaaat cgatggtaaa aaaagtctgt tgatccatcg gaattgtaag tccgcttacc
     4801 gaagtcaaga tatcacggat atctggcagt tcagtagtct ttaagacaag aaaattgatc
     4861 ctttgaagaa gcgcttcata aactgactgg aagctgacga tccacaataa aaccaagata
     4921 caacaaagaa agagaggaaa gaacagctgc cagaaaataa aaaggaataa tttggtttta
     4981 gaaagaccag tcaggcgcca attgatcaat tcctgcttgt tttgcctgac tgaatagtaa
     5041 aagaaaaaga taaaaaggaa ggcaaataga aaaaataaac tgaatatgcc ttttatataa
     5101 aatcggctag ctaattctaa agccggaaga agctctgtag atgcagaagc gccaataaat
     5161 gaaagccgat cttggacttg attggctaaa gccgattgcg aatggtaaag agtcaggcat
     5221 gctatcaata aaaaagcaga aaagcttgaa aataaacaat agagtattgt ctgctttttg
     5281 taataaatta atcgagcagt agcatagcgg attattttca tacttttcac ctctataaaa
     5341 agtatagaaa atgaatatga ataaagtatg aaattccttt agtgaaatca cgaattaaaa
     5401 ccagaaaata ttttgtaaaa agcaagaggt tgtgaagaag ctgccctatt ctattaccgt
     5461 agatgcaagc ttttgaacac tgtttattcg aaaagaggag cagcgacaat aatttt
//
LOCUS       DAFELK010000103         5427 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFELK010000103
VERSION     DAFELK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.111"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            63..1574
                     /gene="gadC"
                     /locus_tag="LP433_002772"
     CDS             63..1574
                     /gene="gadC"
                     /locus_tag="LP433_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBL2006877.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            1587..2987
                     /locus_tag="LP433_002773"
     CDS             1587..2987
                     /locus_tag="LP433_002773"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBL2006878.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(3152..4587)
                     /locus_tag="LP433_002774"
                     /pseudo
     CDS             complement(3152..4587)
                     /locus_tag="LP433_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            4980..>5427
                     /locus_tag="LP433_002775"
     CDS             4980..>5427
                     /locus_tag="LP433_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBL2006879.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVS"
BASE COUNT         1728 a          878 c         1032 g         1789 t
ORIGIN      
        1 ataagcgatt ttccataacc ttggtaggaa tgacaaatta aataggaaag ggaagtaata
       61 atatgaataa aaaaaagtta tctctattcg gtttttttgc cctgacagct tccatggttt
      121 tgactgttta tgagtatccg acctttgcaa catcacaatt acatttggtt ttctttcttc
      181 ttttgggagg tattttatgg tttctaccag ttgctttatg tgctgcagaa atggcaacag
      241 ttgaaggatg gaaagatggt gggattttca gttgggttag tcaaacttta ggagaacgtt
      301 ttggttttgc agctattttt ttccaatggt ttcaaattac agtaggtttt attacaatga
      361 tctacttcat actaggagcg ctgtcgtatg taattaattt tccagagctt aatacagatc
      421 catttatcaa gtttattggt gtattagtca ttttctgggt actgactttt tcacagttgg
      481 gcgggaccaa tcgtaccgct aaaattgcta aagcaggatt tgtcattgga attgttattc
      541 cttcgatcat tctctttggt ttagcagcag cctactttat cggcggtaat ccgattcaaa
      601 tggctattaa tgcgaaagct tttattcctg acttttctca gctttcaact ttagtagtat
      661 ttgtatcttt tatattggct tatatgggcg tagaagcttc agcatcacat attaatgagc
      721 tggaaaatcc ccaaagaaac tacccattgg caatgttttt actagtgatt ttggccatcg
      781 ccttagatgc aatcggcggt ttctcagtag cagcggttat tccacaacat gacttgtctc
      841 tcagtgctgg tgtaatccaa acatttgaaa cgcttatttt acattttaac agtcatttac
      901 attggttggt aaaagtgatt gctctcatga ttgcctgtgg cgttatgggt gaagttagtt
      961 cttgggtagt tggtccatca cgagggatgt ttgcagctgc tcagcgaggt ctgttaccag
     1021 ttttcttccg gaaaactaat aaacaagacg ttccagttcc gttgattatg atacaaggaa
     1081 ttatcgttac tatttgggca gcagtcttaa cttttggtgg aggaggcaac aatttatcat
     1141 tcttagtagc aatctcctta actgttgtca tttatctcgt aggatattta ctatttttcc
     1201 taggttactt tgtattagtt tttaagaaaa aagacttaaa acgaacttac aatgtaccag
     1261 gaaaaactgt tggcaaaacg attatcggtg gaattggttt tattttatca gtgttcgcat
     1321 tgcttatctc ttttgtacca ccagcttcaa ttgcagctag tgagcaccga acataccaaa
     1381 tcatactact tattagcttt gtagtgactg ttcttttacc ttttatcatt tatgaagtac
     1441 atgataaaag tgctcacaca actattgagg aacctactca cgtgaaagct gaagacgtta
     1501 atcccgctgt ttatccagct gctagaggag agcaccacgt tacaaaaaat gatgaacata
     1561 ttttaaaaca ttaggaggaa ttcattatgt tatacggaaa agataatcaa gaagaaaaaa
     1621 actatttgga accaattttt ggctctgcaa gtgaggatgt tgacttgcct aaatataagt
     1681 taaacaaaga atccattgaa ccacgaattg cttatcaatt agtacaagac gagatgttgg
     1741 atgaaggaaa tgcgcgatta aacttagcta ctttttgtca aacgtatatg gaacctgaag
     1801 cagtgaaatt gatgacccaa acgttagaaa aaaatgcaat tgataaatca gaatacccac
     1861 gaacaacgga aattgaaaac cgctgtgtaa atatgattgc tgatttatgg catgctccaa
     1921 ataatgaaaa attcatggga acttcaacga tcggctcttc agaagcctgc atgctgggtg
     1981 gtatggccat gaaatttgct tggcgtaaac gtgctgaaaa attaggtctt gatattcaag
     2041 caaaaaaacc taacctggtg atctcttctg gttaccaagt ttgttgggaa aaattctgtg
     2101 tatattggga tgtggaactg agagaagtcc caatggatga aaaacatatg tcaattaatc
     2161 tagatactgt catggattat gtggatgagt acacaattgg tattgtaggt attatgggta
     2221 ttacttacac tggtcgttat gatgatatca agggtctgaa tgatttagtt gaagctcaca
     2281 ataaacaaac tgactataaa gtatacattc atgttgacgc tgcatcgggt ggcttttatg
     2341 caccatttac tgaacctgat ctagtttggg attttcaatt gaaaaatgtt atctcaatta
     2401 attcttcagg tcacaaatat ggtttggtat atccaggtgt gggttgggtc ttatggcgtg
     2461 accaacaata cttaccagaa gaattagtat ttaaagttag ttacttaggt ggagaaatgc
     2521 caactatggc tatcaacttc tctcatagtg cagcacaact aattgggcaa tactacaact
     2581 ttgtacgcta tggctttgat ggttatcgtg atattcacca aagaactcat gatgttgctg
     2641 tttatttagc caaagagatc gaaaaaactg gtatttttga aatcattaat gatggatcag
     2701 aattgccagt tgtgtgctat aagctgaaag aagatcccaa tcgcgaatgg acactatatg
     2761 atttatctga tcgtctgtta atgaagggat ggcaagtccc agcctaccca ttacctaaag
     2821 acttggatca attaattatt caacgcttag ttgttcgagc agactttgga atgaacatgg
     2881 ctggtgatta tgtacaagat atgaaccaag caattgaaga gttgaataaa gctcatattg
     2941 tttatcataa aaaacaggat gtgaaaacgt acggctttac tcactaaaat tcttcagaga
     3001 aatataaaag aagttaatta actaataaaa ggagttgtga ttaccacaca gctccttaaa
     3061 tctatttgaa taaatatatg atattcattt gttacactct caatcttagc tgttgttcta
     3121 ttcatcatta ctcttattgt aagtagttca gtcaaatttg cttgttcaat tgatcgataa
     3181 cagtatgaat tgtttgaaaa gtaatcggat atataattgt tttctcacta cctaagcctt
     3241 cttggtataa agaactatcg caaagtataa tccgctgagt acaaaagaaa gtgtcgtcta
     3301 ctatttctct aagttgttta caaatgatat tactaataga aaagtgttct cccaaaatgt
     3361 cttctaactg ttgtcgatag tataaatacc taaagtctga cggagctact atgaacactt
     3421 caattggaga tttccgttta tgctcattta aaagacttaa actaatggtt agtttacgaa
     3481 tagaattctc attccaacgc agaaataaat tgttttgttt tcgccattgt tcaagaattt
     3541 catgaacttc taagtacaaa gcgcgttgct cttcatttaa caagtaagtc ttatcaggtt
     3601 gaaatatctg aatatcagcc caaagtgagc ggataaacgg gagaagtgct ttatcaaaaa
     3661 gtatctgatt ttcttcagat atattcagag ataagataag tttttgactg agctcaatca
     3721 ccaaagggtt atctgctaca tggttttgat aaacaacgtt caagtctttt tgtaacaatt
     3781 caaagttatc gcatagataa tttctagagt tgaatagaaa gtagatataa aggcattcat
     3841 cttcgtcatg acataaagag aaagaaagtt gctctaatcc tttctgtatt agctgaaaca
     3901 agggagtatg tcgggcaact cttttttctt cctgactaaa atatattggg ttagtcttag
     3961 atctctgcaa accgatagcg atacctaata aaataaattg tttttcaact gtagggtaac
     4021 ttcttgaaaa aaatgttttt ctacataatc aatcaattgt tgaccgcttt gaataattga
     4081 tttatttagc tggatcaact ctgtccgatt tgtctcatag attatcgtta gtaacaaact
     4141 tcgataatcc ttttcaggaa tttcaaaatg gccatcagca tttaagtact gcatttgttt
     4201 aaaaaaatta atcaactcat ttcgtaagtt gtaaactttg cttaacgaaa tgaaggtagt
     4261 atcagctata ttactccaat tgtgttcccc tgataaataa tgtcctagta cattgaaaaa
     4321 gtcagagcgc tgatagatga gttgagtgag tgccaacctc gaaaacgaag agtcgaatgc
     4381 gactgtaaag ctacttctag atttctccac tgaaataatt tgctgatgga gtatgtcggt
     4441 aatgcattcc aagtcgttag tgacagtgag tgggcaaacg ttcaattgat ctgctatttc
     4501 gcgaatctga atggtccctt tttcgtgtaa ttgctcacaa atgtaaactt gacgaaaaat
     4561 acttttctcc agataggttt ccaacatagt actcctccta gtcattttat acataactat
     4621 tataactcta ccaatcggaa tagtcctgta atatattgaa tcaaaaatat aaattataaa
     4681 ataattagat ggggtatttg gtttaagtat cccttatata gtaataaatt tataggtgtg
     4741 attctcgaat taatacccga aaatgtgaga gaatttttat ggatttttta ggatacaaat
     4801 taattatttt tgcttttatc ctgattacca gtccagtact gtcggtatcc cattttgcag
     4861 caaaatcatg ttgataaagt gacaagaaga ctgatgagat atattatcca aattgagaag
     4921 ataattaatc ggattcttga gtatacccta ctttttaaga aagtagggta tacaagcgta
     4981 tgaataaaga cataactttc cctgtgatgg acgttcggct tgttccaatt accaaaatac
     5041 aggcgaacga ttataatccc aatcgagtag cgtctccgga aatgaactta ttggagcttt
     5101 ctatcattga agatggcttt actcaaccat tagtttgtta ttacaaggaa aaagaagaga
     5161 agtatatctt ggttgatgtg cttcataggt atcgtgttgc taaggaaaga ctcaacttaa
     5221 aagttgtacc ggtaacagtt attgataaac ccatagaaga acgtatggct tcaacaattc
     5281 gacacaatcg tgcaagaggg acccatgaaa taagaggaat ggaaattgtc atccaaagat
     5341 tagtaaaaaa tggatggtca gacaagagaa tatccaaaga attaggcatg gacattgaag
     5401 aaatttttcg ctttaagcaa gtgtctg
//
LOCUS       DAFELK010000104         5341 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFELK010000104
VERSION     DAFELK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.112"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(62..280)
                     /locus_tag="LP433_002776"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="LP433_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="LP433_002777"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="LP433_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="LP433_002778"
     CDS             2092..3132
                     /locus_tag="LP433_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL2006880.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3956..4288
                     /locus_tag="LP433_002779"
     CDS             3956..4288
                     /locus_tag="LP433_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBL2006881.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="LP433_002780"
     CDS             4907..5248
                     /locus_tag="LP433_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBL2006882.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1947 a          730 c          896 g         1768 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccatttgcag aggtaactgc acactacatc tgcaagtggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa aacccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa taatctaaaa aatagttatc ccaattgtta tgattttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacatc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattaac aagtatatat
     1321 atttaaaaat ttaaaattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cctagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaattt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattctaaa
     1621 ggtagtacat aattattata tatatctaac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt agtggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgatactg gtagtactta attatcctta attttaaaac
     1861 caaattttat tcatacgttc ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttcttattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaattttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agcgtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattaa
     4861 tataaagcat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
     5341 t
//
LOCUS       DAFELK010000105         5212 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFELK010000105
VERSION     DAFELK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.113"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            604..954
                     /locus_tag="LP433_002781"
                     /pseudo
     CDS             604..954
                     /locus_tag="LP433_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
     gene            948..1370
                     /locus_tag="LP433_002782"
     CDS             948..1370
                     /locus_tag="LP433_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006883.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2540..3508
                     /locus_tag="LP433_002783"
     CDS             2540..3508
                     /locus_tag="LP433_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2006884.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            3525..4049
                     /locus_tag="LP433_002784"
     CDS             3525..4049
                     /locus_tag="LP433_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL2006885.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTETHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKTEKKWWQFWQ"
     gene            4425..4706
                     /locus_tag="LP433_002785"
     CDS             4425..4706
                     /locus_tag="LP433_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006886.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            4708..5124
                     /locus_tag="LP433_002786"
     CDS             4708..5124
                     /locus_tag="LP433_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006887.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT         1968 a          893 c          867 g         1484 t
ORIGIN      
        1 aaaaaaaaga aaaatccgct tatgcaactt cttctttttg tattttgggg cgctacccca
       61 atccccaagt atcggttatt taatagcgcg gaaatccaaa gaataggacg taccctgaaa
      121 caaaaaaaga ctgctctcac gagcagccca aaatgagatt atcctattca tcaacataaa
      181 aatattacaa agtgaagaac tagagaaaga caaaaaaagc atatcaaatc ctctcaaaaa
      241 taacaagtct taaaaaaatg acagataaaa atgcacaaag aattagatat agataaccgc
      301 gaaaaatcaa gctttagaaa gttgctttta gctagaccaa ttaaaaatca caaagtgagc
      361 gtctctatcc attggtagag gggctacttg gcatagtgta cattatgtta actagctcga
      421 taaataacga ttatgttccc aaaacaatat tttatgaact ataacaaaaa tttgttatcg
      481 catattgtat attttaatta tataattata ggtgtatacc acttaaattt aacacaaagg
      541 cgtggttatt ttgaaaccca aaaagaaaat ttatctaggt ctcctctttt ccttgatgat
      601 tggaatagtc aaattgaatc aaaaagtctt aatcaagatc aaataataaa atatgcaaat
      661 tactgtggtg tttatcctaa aaaagtagca cgaatactaa acctttcaga ggtccaaaca
      721 caactaagaa aaggaaatgc catttatatg ggaactgctg gttatggaaa ttatagtaac
      781 agccgtcatg cacttgcatt atttgggtgg gtcaatcaag gtggttatca aacttactat
      841 gtgtggaatc cttggtataa ctacccaact gtaataagtg caaatgcagg accagttaca
      901 attcctgtac ctggaggtgg ttttacttgg gacaatacca ttacaaattg gtaaataaac
      961 ccattgcttt agttatgggt ctagtgttag ttcttttctt aactagttgt tcaaaaaaac
     1021 aagaaataca aaagactgat ctgattcctt ttctaggaac ttggcaaact aaagatcatt
     1081 cagaacgtct agtaatcact aatttaaata cttcaaaaaa tatagaacaa tataccatct
     1141 tagtaaaaga gaacaatcat aaaattcaaa tcattgataa aaatttaaat ataaatgaac
     1201 aagttttcat ttacaaagca acaaataatt tactaacact gcgctctaat aaaaaacaat
     1261 tagattacac ttttagtttg gattctccaa aaaagctcgt atttattttg acaacgaatg
     1321 atgggacaga agggacagct aaaccaattg aattttttaa agctgattga tgaatagttg
     1381 tttgatatta caaaacaata atttcaccga aggtgaaaca agcgaaactt tacaaaaagt
     1441 ggctagcatt tgctagcctt ttttgtattg tggagcgtgg tttttgaggg ggattcaagg
     1501 gggagcttgc gcccctttga caagcggtta tttgcaccaa atacgtaggt atttggctag
     1561 caaatataga gcttgccaaa cactttagtg agttttgtag aaagtacctt taaaggtact
     1621 ttcacattac gaacgatacg tccgtaggac gtactgaaag ggtgggattt atgagcgaac
     1681 taatgcaaaa tttggctagc aaaaaaagtt aaaaaatata tgctaataat cgagcgaaat
     1741 gaacactttt tcaagtgagc gaatccgcca tgacaaagct gaagcagttt atttcagctt
     1801 tgtcatggcg tgtgcctaga cttttaaaaa agtcggcaca cgagcaaata tctttatcaa
     1861 gctctaattt gcgttttaag acgtttgaaa cgtctaagta tataaatata taagagtagg
     1921 tttaagagtg cttaaatcga attttagagg gcattcagac aactttaggg ttgttagggc
     1981 ttgccctgac cgcctgtaag gcgctttaag aacaagataa gggatttata ctaagactgt
     2041 cttaaaacgt ctcaaacgaa ggctcatagc ttctcaaaga gttccttatg aacattttta
     2101 gcaaaggagc cggaagcgac tgcgcagtat aatgtgagag cagagcgatc acaccttttt
     2161 aagcgactgt agggagtaag attcccagtt gagaaaaatg cgcgaatctg tttggagaaa
     2221 aaagaagtgg ttttttaggc gggaaatttt gtccccctct tttataatct ctttttaaac
     2281 ctctttttaa acctctttac cgtcggctat atccttactc tcccaaggga atgacgcttt
     2341 tatctacatc gttttgtctg tttatctaca tcgttttgtc tgtttatcta catcgttttg
     2401 tctgtttatc tacatcgttt tgtctgtttg tacattgaat tagtacatcg acgatgttaa
     2461 tataagatgt agataaacag gcattttgta tttcataacg tgtatctctt gtgcgagtaa
     2521 gaaaggagct attttaaata tgtctaatga aatcgtaaag tatcatcatg aattaaatac
     2581 aattccgttg cgaaaattta caccagtcga aatgaatttg ttcttttcta tcgtatcaag
     2641 aatgcgtgat gtaggtgata aaaaagtaca atttacattc gagcaattaa aagatttaag
     2701 caattataaa gcaactgcaa atgttcgatt catagatgat ttagaaacaa cgtatgacaa
     2761 attaatggat ttacgttttg gtagaagaag tgctgacggt ttgcaacgtg aacgttttgt
     2821 tttatttaat caatttaaaa tcgacggaaa atctgatatt ccttttgctg aaatacaagt
     2881 tcatgaaaaa gccttaccct tacttaataa tcttgaagaa tgggtgcgct attctctcca
     2941 acaattcaat gaattagaaa gcagttattc aaaaacaatg tttcgattac taaaacaata
     3001 cagaaccaaa ggtttcgctt atttttcaaa agaagacttt catgaattac ttgatattcc
     3061 taaaagttac aaccaaggta cgattgatca acgtgtgttc aatccaatac gacaagaact
     3121 aaccgcaatc tttaaaggtt taacaatcaa aaagaaatac ggaaaaggac ggggaaagcc
     3181 tgtcattggc tatcaattta catttaaacc tgagataaaa aaatcagacg actttaacaa
     3241 acatgcccca acaaaagaag aacaaaacaa agcattagaa ctagctaacc aacaagttca
     3301 atctgaaaaa gcacctactt cattacaaga aaaaatcaaa gaacaaaagc gaaaattgga
     3361 acttttacaa cagttagaaa agttagaaag agaacaaaat acccaaaata aagaaaataa
     3421 tgcacaaaaa tcagagataa attccgatat tccttcagaa ctaaaaaaag acttattaga
     3481 caatcttcaa aacttattca aagattgagg ggtttttaga ttttatgaca gaaaaaacaa
     3541 tcaaagaact tgctgaagaa ttaggagtta gtaaaacagc aattaacaaa aaagtttctg
     3601 acgaaaatcg aaaactttgg ttttcgaaaa tcggaaacaa gtttgtgatt aatgaaaccg
     3661 gacaaaaggc tataaaatca atgtttttta acgaaaacga aaactcaaat caacaactag
     3721 ttggcgaaaa aacgaaaacc gaaacccaca aaaacgccaa ccaagttccc gaattagaag
     3781 tcctttctct cctagaacaa cagttaaatc aaaaagatat gcaactacaa gaaaaagacg
     3841 agcaaataaa acaaatgcaa aaattactcg accaccaaca acaactcacc ctgcaagcca
     3901 accaacaaat cgagaaactg caggaacaac tacagttgac ttatacggaa gaatcttcgg
     3961 aaaataaatc aacgactctt tctgaagaaa cagaatcgat agaaaaacaa tcaaagacgg
     4021 agaaaaaatg gtggcaattc tggcaataaa accagcaatt taaattaata aaaattgctg
     4081 gttttattct tctttttgct tttgcgagca gagcaacatg gacccatgtt gcgatatttt
     4141 ggtggcgccc caatccccgt tttttcgttg aatcttactc ggactgcact cgttttacag
     4201 ctgatttttc tgaattttga aagagcataa ggaaacgtgg tatcactttc ttacgaaagg
     4261 tgctagatag gctgtgccta tcacgtttct cagaaaaaaa tttgctatca cttttttgcc
     4321 attgtggcta ggctatgtat agtgttttgg cgaaaaatag ctatacaaat actatatttg
     4381 tatgatatac ataaattata cgctgatacg aaaggaaaat ttccatggac attttagttc
     4441 gaaatatcaa tcccaaaatt attgcaagaa tagataaacg ttgtcaggaa ctcacaacca
     4501 aaacgggcaa aaaatggagt cgaaataaat atctaaaagt tctaatcgaa agtgattttg
     4561 accgtcaact tatgaattac aaaaaagatc aattcgattt attactcgaa aaatttattg
     4621 ccattcaaac agaaaatacg aacatactga atgactatgt tcacacaaac aaccaactca
     4681 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgtaacc
     4741 ctttatccca gtcacgttga cgttttagat tccatcatcg aaaaaaatcc agacgtcaac
     4801 aattattcag aagccattcg ttttttatgt atgagttatg aacctgatac caatacaacc
     4861 acaaccagta accaagcaaa actcaatgcc atgggaaaag aaatttctat catgacagaa
     4921 atcatggcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4981 tctaaagtgt atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ttcccgacga
     5041 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacct ttacttctgg aaattttgac
     5101 ccaacaaact ttctaaaaag ataaaaaaag aaaccgatcc ctaaaaaaat tcctcgattt
     5161 ctttttaggg atcagtcttc cagcaagatt tgcaagttgg taccaacttg cg
//
LOCUS       DAFELK010000106         5199 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFELK010000106
VERSION     DAFELK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.114"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            23..694
                     /locus_tag="LP433_002787"
     CDS             23..694
                     /locus_tag="LP433_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2006888.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            753..1193
                     /locus_tag="LP433_002788"
     CDS             753..1193
                     /locus_tag="LP433_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006889.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1205..1873
                     /locus_tag="LP433_002789"
     CDS             1205..1873
                     /locus_tag="LP433_002789"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL2006890.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1937..2560
                     /locus_tag="LP433_002790"
     CDS             1937..2560
                     /locus_tag="LP433_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBL2006891.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2616..3002
                     /locus_tag="LP433_002791"
     CDS             2616..3002
                     /locus_tag="LP433_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBL2006892.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3215..4606
                     /locus_tag="LP433_002792"
     CDS             3215..4606
                     /locus_tag="LP433_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBL2006893.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1727 a          861 c         1095 g         1516 t
ORIGIN      
        1 tgatgaaaaa agggggagaa aaatgaattt tttagttgtt ttaaaagata ctctgattga
       61 gcgatctaca tttctatatg ttcaattgca ggaaaataaa acattgctgc atttttcacc
      121 agagttccat ctagaggggc taacattagg agaaatctat caagcagaag ggctgtcggc
      181 tgttttgcac ttttttaagg tagaattgga attaccagta aaagattata tcgagctttc
      241 tcttgaatct tgggatcgag cagtggttga actgtttcca gaaggtttaa tgatcgatac
      301 aaacgatggg aagatccatc tgactgcagc agaactgcaa aaacaaatgc gttatcaaat
      361 agatgacgaa aattcttttt ctatttttag acgtcagcaa aagattctaa aaagcttttt
      421 aaaagtgatc agtaaaaaac ggaatctgat caaaacgaca cagctgttga aaaaatatcc
      481 aggtctgctt cacacgtcta ttcaatttcc tcaattgatt acgatgatcc atcgttttat
      541 acgtatgcaa cagctaccat ctaagaagct gtttcttcca ttgacggaca catttcgagt
      601 agtcaacaga gaagataaaa agaaagtgat tgtgattgac tttaccagaa atcggaatgt
      661 ccttcaccaa gttgcaatgg aaaaggccaa ttaaggcttt ttctttttgg atttttttgt
      721 cataataaat attagatgat ggaggagata atatgatgca aacatggtta gaaaggctaa
      781 tacgatttca gcagaactat cacaaactta tgcagggaag atatgcgaaa tttgatcagt
      841 tgaatcgcgg tctattgatc gctgcgcttg tctttagttt gctaagtcgt tggttgccct
      901 atagaatcgg acaattgttg ttcatcgtct ttttcggatg gatgatattt cgtttcctat
      961 caaaaaaaat ctaccccaga ctaaatgaga atcaacgtta tttgaaatat cttgatagag
     1021 tcaaagaaaa atatcatcag ataaaaaaca aaaagcaagt caaaatggat cgaaaaagtt
     1081 atactttttt tgagtgcccg aattgtcatc aaaagcagcg tgcacctaaa ggaaaaggac
     1141 gaatacgtgt gacatgcaaa acatgtggta taaaattcga aacgaatgtt taagggagaa
     1201 aagaatgaaa ttagtattat tacgtcatgg cgaaagcgaa gcaaattttg aaaattactg
     1261 gacaggatgg ctagatgtcg ccttaacaga aaaaggaaaa gaacaagcag cagttgccgg
     1321 tcaaaaaatg cttgaagccg gacttcaatt cgatgccgtt tatacctctg ttttgaaacg
     1381 tgcgattctt accggacaag tcgcactaga agaaatgggt cagttatggc ttcctataat
     1441 aaaaacatgg cgtctaaatg aacggcatta tggggatctt gtgggtaaaa acaaagataa
     1501 gatgaaagaa atatacggaa aagatcaagt aaaaacatgg cgcagaggat atacggaagt
     1561 tccgccgtta accgcagaaa atagatttga ccgcagatat gatcacttgg atccgcattt
     1621 gatcccatac ggagaaagtc tggaaatgac agtgaatcgg atcattccct tatggcaaga
     1681 tcatctagca ccaaaactaa aagatcggca agatttacta gttgtgggtc atggtaatag
     1741 catccgagca ctgacaaaat atttagaaga tgttcctgaa gatcaaatgg atacgatcga
     1801 tatcccaaat gcacaaccaa tccagtatac attagcagat gatttgacaa ttctggacaa
     1861 aaaaatactt taaagaacac ctttatctaa aagtgagaga tagaaaaaag aagcaaagga
     1921 atggaacaaa aggaacatga aaaattatat atgggacttt gatggtacat tgtttgatac
     1981 gtatcccgca atggtagatg gtgcatggca agcactaaaa gattttggta tcagtatgga
     2041 caaaaaagaa atctacttca aaatgaaaaa gtattctact agttatttga tcaatgaatc
     2101 aaacttgaat gccagagagt ttaatgaatt atttcaccga tatgaaaaag aaagtacgga
     2161 agtttcccgt ccatttccag aaacgaaaca agtactggaa atgctaaaag acaacggcgg
     2221 tcgtcatttc atcctgaccc accgtttgac agaatcaaca tggggcctgt taaaagaaca
     2281 tcgattggca catctgattg aggaagtagt agggatcgat caggactttc ctcgtaaacc
     2341 tgatccagca tctttaaatt atttgatcga tacttttcat ttagaaagaa cagacacgat
     2401 gatgatcggc gatcgtcgtt tagatatcga agcagggaaa aatgcaggag tcgctacttg
     2461 tctttacgac atcgatcatt ttctgggtga gatcccggca gattatgtgg taggaaatct
     2521 gaatgaaatc cttaccttgc agagcatcat taaaaagtag tatccccttt caaaggagat
     2581 atgttataat tttcataaag gagtgataaa attatatgga aatcagaaga caaaaagaag
     2641 ttgtagaagc atttcattat gatatgagat tgccgaacca agaagtagaa acagatttga
     2701 aagtaggctt ctcgccttta aaagaaacga tcgaaaacta tccgaaagaa catagcatcg
     2761 taggagcacg cttagagttc cgtttagtgt ttgatacata tgttttatct ggaagtgtga
     2821 gtcagatcaa tcatatcctc aatcggaaaa ttgaaggtca aaatgatgtc acacaagaag
     2881 aagtggacga gctagtagca ccgttattcg atatcgtacg ccgaatgtct tatgaggtga
     2941 cagagatcgc cttagatcag cctggggtaa aattgaattt tcaatcagaa aaacaagaat
     3001 agacagtaaa aacatacctg cgatagatta aagctatcac aggtatgttt ttttattact
     3061 aattgtaagc aaaaagaatg tcatttcgat aaaaatcgtc taaaatataa aagtcactga
     3121 aaaaaatttt ttcaggagga tggttgaaga atcattctcg ggaaccttta cttccttcga
     3181 tggacttgtc attaataata tgaggaggag aaaaatgaca acactcatca cagttttagt
     3241 ggttctagtt tttgcggcat tattatatgt gttctatcgt atgcaaaagc gccatacaaa
     3301 attttcaaca cgcgtcttta cagcattagg agttggtatc gtctttggcg gtctgcttca
     3361 attgatcttt ggtgtagacg acaaagtcgt tactcaatca atggaatgga tcgggattgt
     3421 aggtcaagga tatgtatcat tcttgcaaat gctagttatg cctttagtgt ttatttcgat
     3481 cattggtgca ttcacaaaaa tgaaagtttc tgaaaagcta gggaaaatta gtgcgactgt
     3541 attgacttct ttacttggaa caacagctat tgcagcattg atcggaattg gttcaacaat
     3601 gctgttcgga ctccaaggag ctaaattcac acaaggagct gcagaaacag cacgaatctc
     3661 tgaactggca acacgtcagg aaacagttga aaacttatcg attccacagc agattttatc
     3721 ctttatccct aaaaacgttt ttgctgattt agcaggtagt cgtgcaacaa gtacgattgg
     3781 agtcgttatt ttcgcggcat ttgtcggaat cgcttatcta ggcgtgaaaa gaaaagcgcc
     3841 aaaagaagca gcattctttt cagatttagt cgacagtctg tataaaatca ttatgcggat
     3901 cgtgacgctt gttttgcgtt tgacacctta tggagtattt gctttgatga caaacgtttt
     3961 ggcaacaagt gattttgcag ctatcgtcaa tttaggtaaa tttgtcgttg cttcttacgt
     4021 agcattgctt gctgttttga ttgtccactc actgattttg attggtgcaa aagtcaatcc
     4081 aatcaactat ttcaaaaaag cctttccggt attgagcttt gcgtttactt cacgttcaag
     4141 tgctggagct ttgccattga atatcgagac tcagacaaaa gctttaggag tagatgatgc
     4201 aacagctaat ttctcagcaa gttttggttt gtctattgga caaaacggct gtgctggcgt
     4261 ttatccagct atgttggcaa cgatcgtcgc accagcagct ggagtgaatg tctttagttt
     4321 ggaatttatt ttgatgcttg tggcaattgt aacaatcagt tcttttggtg tagctggagt
     4381 cggtgggggc gcaacatttg cttcactgat cgttttaggg gcaatgaact tgccagtagc
     4441 aatcgttggg ttagttatct ctgttgaacc attaatcgat atggcacgta cagcagtaaa
     4501 cgtcagcggt agcatggtag ctggtatcgt gacaagtgca cgcatcaaag atttagatcg
     4561 cgatgtcatc aatgatgatt ctaaagtgat cgatgtgaat gcatagtcaa aaagaggttg
     4621 tgatagaagt ggtcagcttt aagaaataag aagaagtttc ctaaaaatag tttctcaaat
     4681 ttttgtgaaa tttcggctta tttccgagaa gctacttctg aaacaccgtg aataagaggt
     4741 tgtgaaaaag ctgccctgca tcaagtaata agaacagcca aacaaaaata gttcctcata
     4801 ttttacgttt ggttgagctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
     4861 aggtcgtgag cctgccgttt cactctgagt cacaaagagc aatttcaaaa aatagcttct
     4921 catgtttgtt gaatattgtg tcttgtgacc gaggagttgt caggagaaca ccgtttacca
     4981 gaggttgtga cttgttttta gtcacgacct ctttttttat ttattccata taaatacaca
     5041 ttatttattc cgaaaagtga aagcgcaaat aacaaaaaca accaacttat ttattattaa
     5101 agaaaagcgt atttaagtag gacgattctg ttgagagctt tcgtagattt tcccattttc
     5161 ctatggtaaa ctgacaaagt tgagaatgtt agaacagat
//
LOCUS       DAFELK010000107         5110 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFELK010000107
VERSION     DAFELK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.115"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..2373)
                     /gene="esp"
                     /locus_tag="LP433_002793"
     CDS             complement(<1..2373)
                     /gene="esp"
                     /locus_tag="LP433_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBL2006894.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVK"
     gene            complement(2991..3425)
                     /locus_tag="LP433_002794"
     CDS             complement(2991..3425)
                     /locus_tag="LP433_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006895.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3442..4647)
                     /locus_tag="LP433_002795"
     CDS             complement(3442..4647)
                     /locus_tag="LP433_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBL2006896.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
BASE COUNT         1617 a          933 c          684 g         1876 t
ORIGIN      
        1 tttcactgca aagactgttg ttccactttc aatacttgtt ccttcccctg cggtgaaggt
       61 tactttgtgg tagcctgcag gaatgttttc tcctggattt tcataaatat ctttacttac
      121 agttactgct aaatcggtcg tgcctacaga accatcttgg taaacaattt taataggaat
      181 tgttccagta atcggctccg attctcctac acctttagct ggagtgaatg taacaatacc
      241 agtgtttgca tcaacacttg cattaccgaa gtacttatta tagacatctg aaattgaaaa
      301 ggcatcttta gctaaaggaa catctggttt atcaaatgta ggttttccac tttgaactgt
      361 cgtttctgga gttgttgtta taggtacgta tgttgcatca ttttccatag cttgagaagc
      421 ttttacagca aactctacat ccacgtcgaa agttcgattt ccgatcttaa cagttacaat
      481 acctttcgta ctatcagtaa cgttagaagt atcaggctct gttttccatg aatactctgc
      541 atcttcaggt aagtttttat tattccgaat tgattcttta gcatctggtt taaatccaac
      601 taccacggtt tgtttatcaa ccgcttttgg tgattcctta ataacggttg aaccttcttc
      661 tggtttatca aaacctggag aaacgatttg gatttttaat tcatctttcg cgattaattt
      721 acttgaatct acacccgtaa attcaaattc tacagtatct gaaattggag ccccatcttt
      781 ttcatttgga gcgatagttt tttctgctaa tacagtacct tctttatcaa caagttgggc
      841 tttgtgacct gttcccgcta actcgtggat gaatactttc cccttaactg ttgtgtcaac
      901 atcatatact tcttctaatt caggtttccc gatatatgga ttcgtgtctc cgctctcttc
      961 tttatcgtca gggtttccat caccatcaat atcttgcaaa taataataac ctgttccata
     1021 agtgttctgg attaattttt tattcgtatc cgacaaccaa gaatcaaaga tgaaatcttc
     1081 accaaatggt ttattttctt caacttgtgc tgttgctttc atatcttcta agatttcatc
     1141 taatggctta gtcaattgta aaacatatcg aataacgact ggacgtggac ttgcattagc
     1201 aaaatcgata agtttagtta aatcattatt agttattgaa cctatgccat aattttcatg
     1261 accttcccgt cgctcgattg ctaaatcagc tacttttgtt ccggattcaa acgaaacatc
     1321 atatgttact ttgtcagcct gaaccatgtg catctgtata cccgctacat atggaactaa
     1381 tcgttcatca attttgtaat tagcatacca aggcgtgccc tttgcggaag atgaatatga
     1441 gaaattataa tttttcgtta acttatgatc taagattata gctccattag cacctgtgga
     1501 tcctgaacca tcttttgttt gagtattagg tttctcatat tttgcactta ctgatccatg
     1561 tttaaactgg tcaggattat tttcagatac atctaagcta ttatagaaat catctgaatc
     1621 tgttaaaaag tagcccgtac tatcaatacc cggtacaatt ttatcatcgt cttgatgact
     1681 taccaagtag attcgataca ttaaacgatc ggtcttgaga ttgtctatgc ctatctcttt
     1741 aaaaatttca tctaggctct tttcaaacgt aattacccca ttaggagcgg tttgcgtatc
     1801 ggttgtttct gccccagcaa ataatccatc acttgcacga atataattga ccttccaaat
     1861 atttgtaggt ctacccagcg aatcattaat tcttacaaag gtccgtctag aagatccaat
     1921 tcctttcttt ggatcgacct gaattttttc tacatattta gctaatcgtt catctaattg
     1981 aagacggatt tcccagtttt tagttgatgc tgcaatatta tgttttccgt aaacttcaaa
     2041 tccaattgta ttgcctttta gtgtgtctcc agttagttct tgaggactaa attgtaaatc
     2101 cgaaaagtta taatttttcg tataaccagg attctcctga aaagtattcc ccgaagctac
     2161 tttgtcacct acttgtacgg agcttatcgc tgtttcaagt gggctgcttg gagaaatttc
     2221 atcttgtgct ttaactagtt cagttgttcc caagacaaga ccaacaccaa tcaaaacaga
     2281 tgcaacccca acacttaatt ttttgatact gtacttcaat actcgtttct ttgttttttc
     2341 tagaaatact ctcttattat tcttgctaac cattattcaa atcaactccc ttaataatta
     2401 ctttcctagt aagaataaaa gataaatctg atacgtatta ttcacagaat aggaatctta
     2461 ctaaccttat gttaactaat ttacttagag aatttcatga acattacaac aaaaaaaagt
     2521 acatttcttc atgttttttt cggatatttg tgctttttaa ccattcagca gctgaaaaca
     2581 tataaaaaga tatgtatgta ttctttctga aattaagttc atttctatgc gatgaagcat
     2641 gttttcaaaa tattaccctt tcttagatta aacttcagag tattcaaata acggaataag
     2701 gagccttatc ccgcattact gaatgagact gtgacataag taaaaaggtg acttcaaatt
     2761 ccttcttcgg aatttgaaat caccttcttt ataattataa agtatcggtt tcacagcatt
     2821 tctgaatgat tcctagaatc ttaaacgaat gattggagtt atcaacattt tttcactcgt
     2881 ttttagcgaa acaaaaaatg acatttgtca cagcctcatt aaattattga ttctttttct
     2941 ttataattga attgtccata tttaaagtgt ctagtactct acatgaataa ttaattgctt
     3001 tcactcaaat acttataatc tattaacttg tagttgttta acttttctga aaaagttaga
     3061 cccacgtaat aatcttccca gctttctctt tcaattaact gatccaattt ttgataatcc
     3121 ataaattcat catgtatcaa aaagaataaa taacttgata ttttagcatc tagcttaatc
     3181 agattaaata atgtttgttt aaaattgcta ccattaatat gactgataga ttctctagct
     3241 tcttcacata aactttttac tttattaatt actactttgt catattcatt taacacacta
     3301 ttattaccat tacttagacg ctcagattct acgaaacaac tcaaatcaga aatttcccaa
     3361 aaaaattttt tgttaaaatc caatttcctc aactcctcca aactacgtaa atgatatagt
     3421 ctcataataa aataaaacct ctcagctaat gttgttgaaa ttgtccacta aacctaattg
     3481 atattgctta ggagatacac ctgcgtactt tttgaatact ctcgaaaagt gtgaagaatc
     3541 tgaaaatcct aaacctaaag aaacttcact gatagtatgg tttgatttca acattatttt
     3601 agccgtagaa atttttcgct tagagatata attataaatc gtaatatgca tttcattctt
     3661 aaagctttct cttaatttag tttcacttac agaaaaataa ttagctattt cctttacagt
     3721 aattctttta tagatattta agccgatgaa ttgaacgaca gaagaaatta agggagaaag
     3781 atgctctatc ttagtttttc cgatttcctt agtataataa acaatcccag aatccctcac
     3841 ttttaagacc tcaggtaacg atacagctaa ttcgttttct tgtatcaaag catctctact
     3901 ttgatacgct tctattatat ccattcctaa tgttatagac gtttgtgcta acttttcaaa
     3961 aacaatgata gaataatttt tttcagaccg aatcgtatct ccactaacac ttggaattat
     4021 tccattactc agattaaaaa ccatgttttc taaatttcga atatctccat ttttaacata
     4081 ttccagtatt ttattttcat aaagaaacag atatatttct ggatcgtaat tttgtgataa
     4141 cagattatct attttgattt gctcgatagt tttacttaga ttttctgtat attcaattaa
     4201 cggttcatgg aatagatctt ctatttttcc agtaaaaaaa taatgaacta aaatcagaat
     4261 atctcgaatg tctcctaaag aatacaaagt caaattttgc aatgaattat agagtcgttc
     4321 tctatcagcc attgcaacat tcaaattgtt catttttagt ttaaaaaaaa ctttatcaat
     4381 attatttgct ctaaatggac caaataagta atatctggtt ttaaacatgt atagaagaaa
     4441 catctcatta aaatcaccag taaagaaatg gaaatcttta gtttttttaa tattatcagt
     4501 tagtaacttt ttataatcat aaaaaaaata agtagttcta tctgagcgat actcttttat
     4561 aatactgaat tcggaattaa aaaccacgat aggtaacttt aaacaaacat gaagagactt
     4621 taataagact tctttatctg aaaacacttt tgtttctctc tttcctttct acatcattaa
     4681 atagtatttt atacgttatc taaaatacta ttcctctgtc aaaataagct aacttacttc
     4741 attataaaat atccacttat cgctttcatg tatattccac cgtaaaaagt acattttatc
     4801 accgagaact catcattttt catcatgatg aatactattt acatatatct agttcaaaga
     4861 caataattat tatgatccgt tattatctaa gcactataca gataatagga atttttcgtt
     4921 tctaaatatt ccaatttggg aatccaataa aaattttcgt tcaaatacgt gtctattcga
     4981 actcttttct agttgttaat tatgaagggg gaagaaataa aaaatacaat ctatacacga
     5041 ataagaatat tatccaaaag gaggttttag aaaagattta ttatacgtaa aaagctcaag
     5101 acattttctt
//
LOCUS       DAFELK010000108         5006 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFELK010000108
VERSION     DAFELK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.116"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(37..1257)
                     /locus_tag="LP433_002796"
     CDS             complement(37..1257)
                     /locus_tag="LP433_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBL2006897.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1888)
                     /locus_tag="LP433_002797"
     CDS             complement(1277..1888)
                     /locus_tag="LP433_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL2006898.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="LP433_002798"
     CDS             complement(1931..2863)
                     /locus_tag="LP433_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBL2006899.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3284..4144)
                     /locus_tag="LP433_002799"
     CDS             complement(3284..4144)
                     /locus_tag="LP433_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006900.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
     gene            complement(4276..4956)
                     /locus_tag="LP433_002800"
     CDS             complement(4276..4956)
                     /locus_tag="LP433_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBL2006901.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIQA"
BASE COUNT         1416 a         1007 c          823 g         1760 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttgtcaaccg attttatata tttttttata taataaggta
     3001 attttaatat aaaattttat attgtaaaaa aacaaataag ggaaacaaac aacacatttt
     3061 tgtgtgttgc ttatttccct ctaactatcg ttttctattt gatggttaac ctacttaaaa
     3121 taaatactgc aacgacaaac ggagatcaag catgctttgt aacgtatttt acgataatta
     3181 cgactttatt ttattactct atcttgctgc catacccgtc tatccctaat catctttggt
     3241 gaattttttc aaagttagca taacaaaaat aagtattttt tccttagtta atcaatagta
     3301 tcattttttt catatgattt aattcatcaa ttaatttttt gtttttatta attttagcaa
     3361 aagctagtgc atcttgaatc aattcgagca cttctgcctt cgacttattt ttagcctgtg
     3421 cgttcttcgc taattgggca gcagctcgtg ctaagtaata agtcaaatgg ttatccgaac
     3481 aaatatcgat tgcgtaattt agtagtgcat cacttgtttc caaatcaccg tcttgcgcaa
     3541 aaaaaacacc acaatgaaag acgatattta acacccgcca gatatcttct gttgtacgaa
     3601 tcggatacgt ataaattttt tcaaacactc gattgaaata aacttctgct ttttccaact
     3661 ctttttctct agcatagacc attccaatac ctgtatatgc caataaacga aacaacgtgt
     3721 tggctgtttc tgccatcaac aactgatcaa aatggaacaa cacatccgta attggtgcat
     3781 tcgtaaaaat catttcaaat ccttttagat agtagtaacg tgcaatcagc tcagactcgt
     3841 caattacctt gggatcaatg gctgctaaaa tctgtgtcaa ttgttcatat tcactcgtaa
     3901 tcagtgaaaa ctctgctttt tctagctgtt catcaagttg tgtattgatc acgttcatcg
     3961 aagaaaaaag ttcaactaac ggaagattga ttcgattaca taatttgatt aaaattttta
     4021 acgaagggac ttgaccattg ttctcaaatt tacttaatgt tgcttgtgta caaattcctt
     4081 cagacacttc tttttgagat aagttggcag cctttcttgc cgtaataaat ttttcaatgt
     4141 tcattatttt ctctccaatc agacctcaca cgaaaatcat ttctgtctcg attttagcat
     4201 gttttctttg ggaatgcttt aggttctgtt gcaaagtttt aaataaagaa taaagtccct
     4261 tacggtatct atgatttaag cttggattcc caataatacc ttgatttcag tacagaccga
     4321 aaacccgaag agagtgcctt cttttcgggt tttcttatat aatcctcgga tggcttccat
     4381 gcctttaatc gtggtagagg cagtgcgtaa acttcgatag aatttattgc gtctctttac
     4441 tggacgatgg tcttgttcaa tcaaattatt caggtattta atggtacgat gttctgtccc
     4501 ttgataaaag ccgtattctt ttagtttctt aaaggcactt gtaatagagg gggctttatc
     4561 tgtgactaca accttcggtt catcaaactg cttcactaac cgcttaagaa aagcataggc
     4621 tgcttgtgtg tcccgttttt tacgtaacca aatatccaag gttaaaccat ctgcatcgat
     4681 ggctcgatac aaataatgcc attttccttt aattttgatg tacgtttcat ccattttcca
     4741 tgaataaaag gattttttat ttttcttttt ccaaatttga tagagtagtt tgccatattc
     4801 ttgcacccaa cgataaatcg tcgtatgaga aacgttaatg ccacgatcat ataagatttc
     4861 ttgaacttca cgatagctaa ggttataacg aagatagtag cccacggcta caataatcac
     4921 atcctgctga aattgctttc ctttaaaatg attcatcgtc attcctcctg ctatcttttt
     4981 ctattattct accttatttg atagta
//
LOCUS       DAFELK010000109         4902 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFELK010000109
VERSION     DAFELK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.117"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..181
                     /locus_tag="LP433_002801"
     CDS             <1..181
                     /locus_tag="LP433_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006902.1"
                     /translation="GVKPSTIKPSEYQALELTYAKFAQIKKAKAMASDWLDTFESIEK
                     NGAFYTIESEEKDNE"
     gene            174..881
                     /locus_tag="LP433_002802"
     CDS             174..881
                     /locus_tag="LP433_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006903.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            1262..1441
                     /locus_tag="LP433_002803"
     CDS             1262..1441
                     /locus_tag="LP433_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006904.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            1782..2045
                     /locus_tag="LP433_002804"
     CDS             1782..2045
                     /locus_tag="LP433_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBL2006905.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            2039..2389
                     /locus_tag="LP433_002805"
     CDS             2039..2389
                     /locus_tag="LP433_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2006906.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(2413..3027)
                     /locus_tag="LP433_002806"
     CDS             complement(2413..3027)
                     /locus_tag="LP433_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006907.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            3341..3763
                     /locus_tag="LP433_002807"
     CDS             3341..3763
                     /locus_tag="LP433_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006908.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            3773..3976
                     /locus_tag="LP433_002808"
     CDS             3773..3976
                     /locus_tag="LP433_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006909.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            4187..4771
                     /locus_tag="LP433_002809"
     CDS             4187..4771
                     /locus_tag="LP433_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006910.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         1718 a          733 c          922 g         1529 t
ORIGIN      
        1 aggtgtcaaa ccaagcacta tcaaaccttc cgaatatcaa gccttagaac tgacttatgc
       61 aaaattcgca cagattaaga aagctaaagc aatggctagc gactggctag atacttttga
      121 aagtatcgaa aaaaatggtg cattttatac gattgaatcg gaggagaaag ataatgaata
      181 aggtggttta tcagctaaca acagaagatg tttcgcaatt tttaacaagc aaagaacact
      241 tgaatgaagt aatcagacgg attcaaaaag actttagttg tatggaagaa atgaagtact
      301 ttattcaaag agtggaagaa cagttgtata tggaaagcga aacaagtcaa acgaaggtca
      361 cagtcagcca taatcattta gacgtgtata aacgtcgtcc tgaaacggta aaaaaaggaa
      421 cagagcttct acgactagaa acagaaaaat acatcatgaa tgtgtaccta gaaaggagtg
      481 agctggtcga aaactttgtc agctacacga tttgtaggaa acactattac tcagaatcag
      541 aatattattc aattttcgag agcatggaat taatggaaga agaaatggaa gagctaaaca
      601 gcaaaaatgc gacggtagac gattattacc ttgtatttac taggtttttg acgtgtggga
      661 cggaatctat cgtgttaatg ggaatggatt atgaactcgc tgtacccgaa gcatttttga
      721 gggaatatgt agaagaagta gataacccag gcgacgactg gtacacgact ttaactgatt
      781 ttttagacac ctacacttac gacgatacag aagaaatcca aaatgaactt gaccgtaaac
      841 gaatgccata tcaacgattt gaaaggaaaa aaggtaaata accatttata ccgaaaagtg
      901 aggatgtgtg aaataagaac aaaaaacctt gaaattaagg gaatggttct tatttcgcac
      961 caatcgctcc aaccgccccc gccgcttagg tggtgcgaaa taagcgggca aagcccgata
     1021 acctaagaga aagaaggaga tccatatgaa taaaatcatt cctctattgt tcgtactgtt
     1081 tgttggcgag atacttatgc gtcatgctgc agctgtacat ttaaacttcg tagtattctt
     1141 aggaatactg gtattttgtt tgatcttttg gcgatttgta ttagcccttg tgagtctact
     1201 attcaagatg attgcagcca tatttttcat agggttattt cgatgaaagg agagagtact
     1261 aatgccaatt gcaataggaa ataaacggtt acccgtgaca ttagatgaaa agagacaaaa
     1321 agaattgcag caactaaagc agaagtacgg aaaaagtgaa tctaagatta tgtgtattgc
     1381 gttagatcta ttgatcgcgc aagaaaaagc aggatttgat ataccagcac taaaaaagtg
     1441 acgtcacttt tcatttgaag aaacaaaagt gatagcactt aattgttcct actatttaga
     1501 atattttcta tgtccttttt attccatttt gtatcaataa ctatgaaatc tttaaagtat
     1561 ccagaagaga ttatttttag atcaattttt ttcttacctg attctaaaga ttttgttttc
     1621 ttaaacatat tatgatttcc tttcgactat tttcatataa atgttaacat agtttatgga
     1681 ttcatggaat gttaatctaa tttaatagaa aaggataatt aagtatatac gttttttctt
     1741 atgtatgtta tactatgtat atacagaaag aggtgtctac tatggaaatg ttacctataa
     1801 aaaaatgggg aaatagtaat ggccttagat tgccaaagta tattatggaa tatcttggaa
     1861 ttcatacaga agacaaagtg aagataatac aagaagaagt aaacggtcag aagcggctaa
     1921 ttatcgaagc ggctaatata gaaaatgaat taacaattga acagttattt gaaaattaca
     1981 ctgatgaaag aaatcatgtg acgattcaaa atttaggtga agcagtaggt aatgaaaaat
     2041 ggtgagaaaa cctagacaag gcgatattct attattgaat acagcacctc gatctggaca
     2101 cgaacagaca ggtaaaagac cttatattgt tttaagtcat gatattattg cggattatag
     2161 taacgttgtt acagttgctc caatttctag tacaactaga aactatccgc tatatgtaaa
     2221 tataaactca gaatatgaaa tgaagacaac aggaaaagta ttattagatc aactaacgac
     2281 aattgattat gaagccagag agtgtatttt tttggaaaaa gcgcatgata gtttagttga
     2341 ggagttattg atgaaagtta gaacagtttt tcaaaaagta agcaaataaa atagaaacag
     2401 cagcatgatc aactattcgt gattgaccat gctgtctttt tttattctat atacggtttg
     2461 tctcgtaaca ttgtagtctt ttgcaatctt agcgatcgca acaccttttt ttagatcctc
     2521 aacgatgttt ttataaacaa gacgacgttg gggatctttt gcattggcac tgtatagctt
     2581 aggacgtcct ttataaacac cgttcgcttt tgcaatctta atgccttgtg cctgacgtcg
     2641 tttagattcg gtacgttctt gttcagcgat catggccaaa atttgaatga tcaaatcttt
     2701 aatgaattta tccaggagag gattgccaat tgcttcggcc atgatcggta gacttgtgat
     2761 gatcagctgc acatttttct tcttcaagta attgactgaa gcgatgatct cgtcgtaatt
     2821 tcttccaagt cgatcaatag cttccacaat aaaaatatct tgatctcgga cgaaatccag
     2881 tgcttcttga aaaacaagtc gatgagtaat cgttgcgcca gattgtttct caatgaaaat
     2941 tctctctgca ccgaattttt tcatttcttc aatctgccgt tgttcatttt gatcgatgga
     3001 tgagacacgt atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaaa
     3061 acaccctaat catacacgag aaaaccagat ttttcaatgt cgcggtcgtg tctagttagg
     3121 gtatacctta tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt
     3181 taaatggcaa tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat
     3241 taaaaatata ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta
     3301 agaaaacgtt ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt
     3361 atctttaggt attttaacta ttggaattag tgtaactgga actacaattc ctacatttgc
     3421 tgatagtaca aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga
     3481 taggaacgga atagccattg gtaacccaac taacgactta actgttactg aaaattattt
     3541 aatagtttct ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat
     3601 gatttttgat aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa
     3661 aagaaatggt tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa
     3721 caattggatt gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga
     3781 atttgtgaac acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc
     3841 gaaagaagaa tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa
     3901 atcaatttct aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata
     3961 tcaaaaagaa aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa
     4021 ttgaaagtgt tcataaaatc acccatttct ggacactttc tttttttgct ttatttttca
     4081 aaaaaacaat tcatttcatg ttcataaacc cataacaata tctatgttca gttaaactat
     4141 atggataaag ttatgttaca ataaaattaa tgaaggagtg atttttttga aaataggata
     4201 cgcccgggta tctactggtt tacaaaattt ggatttacaa gaagacagcc taaataaatt
     4261 tggttgtgaa aaaattttta ctgatcatat gagtggggca aaaagtaatc gaccaggatt
     4321 agaaatggcc attgattttg ttcgctctgg cgatacactt gtcgtttggc gcttagatcg
     4381 tttaggtaga aatatggaag atttgatttc aatcgtcaat cgactgaatg agcgtggtgt
     4441 gagttttcat agtattcaag aaaatattac gatggacaaa tcaagttcta caggacagct
     4501 catgtttcat ttgtttgcgg catttgcaga atttgagcgt aatttgatcc tggaacgatc
     4561 cgcagcagga cgagcagctg ctcgtgcaag aggacggttt ggtggtcgtc ctgaaaaatt
     4621 gtctgaacaa gatttggaat tactgaagac tttagtggat agcggtacac ctattaagac
     4681 tattgcggaa cggtggaacg tctcaagaac caccatttat cgttatttgg caaaaatgga
     4741 ggagaaaaat ggaaagacaa attctcatta gtttttgtca tttaatgctg aaaatttttg
     4801 ccatttatct agaaaagtga caatagtatg agaatttttt gtaagtgtct actgataact
     4861 tattctcaaa tgttgtaagg attttattca tttgttaata tt
//
LOCUS       DAFELK010000110         4878 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFELK010000110
VERSION     DAFELK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.118"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..142)
                     /locus_tag="LP433_002810"
     CDS             complement(<1..142)
                     /locus_tag="LP433_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2006911.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQ"
     gene            complement(183..437)
                     /locus_tag="LP433_002811"
     CDS             complement(183..437)
                     /locus_tag="LP433_002811"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL2006912.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRPQRSNKPIMDRLQLTRQKN"
     gene            complement(548..802)
                     /locus_tag="LP433_002812"
     CDS             complement(548..802)
                     /locus_tag="LP433_002812"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2006913.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(995..1270)
                     /locus_tag="LP433_002813"
     CDS             complement(995..1270)
                     /locus_tag="LP433_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBL2006914.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(1242..2195)
                     /locus_tag="LP433_002814"
     CDS             complement(1242..2195)
                     /locus_tag="LP433_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2006915.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            2807..4300
                     /locus_tag="LP433_002815"
     CDS             2807..4300
                     /locus_tag="LP433_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBL2006916.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            4435..4740
                     /locus_tag="LP433_002816"
     CDS             4435..4740
                     /locus_tag="LP433_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBL2006917.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKGSVAKF"
     gene            complement(4774..>4878)
                     /locus_tag="LP433_002817"
     CDS             complement(4774..>4878)
                     /locus_tag="LP433_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL2006918.1"
                     /translation="MEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT         1570 a          824 c          853 g         1631 t
ORIGIN      
        1 attgctttac ccatttgtca aatgctgaag ccgttagttc atattctcga atgatttcta
       61 cacgtggctt tccagctaag taaagattga cgatttgttg cttgaattct tgtgaaaaag
      121 ttcttcgtgt tctcttagac ataaaaattc ctcctggtat gttttcttct agtctacaca
      181 ccttaatttt tctgtctagt taattgtagc ctatccatga tcggtttatt agacctttga
      241 ggtctatatt ttttaactac aatcgacctt aaatttaatt gtttcattag cttttggaca
      301 tgtttaagag atactgaaat cccttctttt aataaaactt gatggatctt tgtggcacca
      361 tagcgttgtt tattcgtaaa aaaaattgtt gaaatcttct ttttcaactt attatttctg
      421 atttctgtag ctgtcaacgg tttattctta taaaaataat agacacttct agggatttct
      481 aataaccgac acaacaaaga aacagtgtaa tccttacacc atttttcaat aaattgaaca
      541 agcgaattta ggttttccga gagaatatgg ctgcggcttt ttttaagatt tcaagttcct
      601 catttaaacg agcattttct tttctcagtt cagctacttc ttttccagtc agtcctgtgg
      661 actgatcagg taaatataaa ttcttccatt tgtaaatcgt tgcttcagat aagccatatt
      721 ctttcgctaa ccctcgaaca gaacgtccag tttgattcag ttcaacaatc atttgtttaa
      781 aattttcttc atatcgggtc ataaaaattc atcctctcgt agataagttt aatttattct
      841 tgtctctacg aaaagctgtc taagatttga tactaacacc aaatgttgta tacccccaaa
      901 caatacacat attttgaagg attaggatta ataaagctaa aaatatagta agtatactaa
      961 atatatttac tatatctagt atacttacta tattttaatc ttttgatcgt ctattatata
     1021 taatccgttc ctcgtcgttt aaagtatcaa cataggcgtc cattgcaagt ttgactattt
     1081 catacatagg aatatctttt gcataactaa gatcccgaat ggtttttagt acgggaggat
     1141 ctacttgaac tggttttctt tctttcgcag tgtactttcg ttcccctaac tcgacattaa
     1201 tatcatcttt aattgaaata tcttcagcac caattttctt cttatctttg ttcgttggta
     1261 ataatgccat ttagtttaat ctcctttcca agaggtagga tatgattggc cattgagtca
     1321 gcatatttag gtgtataatc aaatccttca atatcaccat gttgttcata gtattcaatt
     1381 ctttcttcta attctgtaaa gatgtctgca aaaatagccc accatcttcg atctacataa
     1441 tcatttaatt ggataccatt ctcaccatac atttctaacc gatccgagcc tttaacaatg
     1501 cttttaaaaa tgtttgattc accatactta tcaattgttt tttgatagtt tgcgtgttga
     1561 gaggaacgtc gcactgagaa aagaacaggc aaaattccaa tgatttgaag atgagactct
     1621 tcaaaattcg tgacaatcgg aactaaaact ttattaataa aatcttctgt tccttccatt
     1681 gcgtaccgtt ttaattcttg cattgcaata atataatctg cagcagttaa gaatgcacga
     1741 accacattat ctgttgatgg tgggcagtcg ataaagatat aatcgaaatt ttttctcaat
     1801 tcttctaaag gtttaatgaa ggccaatgat ctcttacgac gatcaggata tttttcggac
     1861 aagtattcat taagttcttc agatccagga gagccagcca taatatataa atgtggactt
     1921 acttgagtaa tacctgaaac ccagtcccct tttttgattg ctgcagacat ggatcgatca
     1981 aagctagtaa tttgatacgt tgatccaatg ttggaagtag tatttctttg ttggtcataa
     2041 tcaattagca acacgtcttt ttcaaaaagt tgactagaaa caatcgctaa taaatcattg
     2101 tctgtagtct taccaatgcc gccttttcta cctgtaagca ttacaacttt tcctagttta
     2161 tctgatgttt taaatgcagt ccgtaagttt tccatagttc cctccaattt cctatactaa
     2221 atatatttag tatacttcat atacttaata tattcgatat atctaatata ctccaaattg
     2281 ataagaattc agactttata aggaatatag tggatatact aaatatattt gctatattca
     2341 gtatatcaga tatattcaaa atgtcaaaat atatttgtgc gttttgcgtt gacaatttag
     2401 agtgaaaaga ggtaaactta attctataga aaccacagat aattcactat ttacaaagta
     2461 gcaaaagcag tggtactctt taaacagaaa aattacataa aaaaaagaga cggaaataat
     2521 tgattttagc agaatcaatt atttctgaat cacatggtta ggacatgtgt tcacgctcgt
     2581 ctcaagaata tgtaagtagc taccaactac ttatattaaa agttgatcgg ataccttttc
     2641 cgattgcctt tattctacca aaaaaaggcg agcaactcaa cagaagaacg tttatttagt
     2701 gtacttaaat taaatattct taaacactga agagagaaca catactatgg ctgagattaa
     2761 agctaaactg tgttctcttt ttgtttgaga aaggacgtta caatcgatgt tgagcgaaat
     2821 ttattcagct attcttaaaa acggcttacg tacatacaaa tatcgaaaca gcaccatgaa
     2881 acctgcaggt catattgatt ccagtaggag tggtgctatc tttgcgtacc gtagcaagca
     2941 attaatgaat gttgggcgtg gtatggtcat tacttcggaa gaagctattt tagagaacga
     3001 aaagaaacta acgcattgga cacctaatac ctatcgcttt ggtacttatg cggatgatta
     3061 tcgaacagtg gttaaaggtc attctgagaa aaacttaagt caaatcaaca catttgtagt
     3121 tgatatcgat tcaaaagaga accatcaagg cgaaattatt ttagcctgtt tagatcaagt
     3181 gggctacatg ccaacgctaa ttttagaatc agatcatggt tatcaagttt attttgtact
     3241 aaagacacca ggctatgtca caaagaaaag caatttcaag gtgatcgatg tagcaaaaaa
     3301 aatttcaaaa acaattcgtc tacagttggc tgaaaaattg tccggagtgg atctaggatg
     3361 taaccacttc ggaattgctc gattcccaca agaaaataat attgttttta aagaaatgaa
     3421 ctatcagtat tcttttgctg actggattca atggtcgatg aagcttgaat cagatcaaaa
     3481 aacaaaagaa gatcgagaac gaaaactaat tgtctttcct gagaaaaaag aaattcgtca
     3541 agtagatgaa ccgtggttcg atatgttact tcataaagca aacatcgtcg gcggagaagg
     3601 acgtcttggt cgaaataatg tgattttcac gctttcttta gcttattact cttcaggtta
     3661 tgcattggat acttgcgaat acaatatgtt cacattcaac gaacggttac aggaaccgct
     3721 atctgaagca gaattagtaa agattgtacg tagtgcttat tctggtaatt atcaagcagc
     3781 aagcagagaa ttcattattg aattgtgcca gcaatgggtt tcaccaacct taaaaaataa
     3841 tgatctgttc attcaacgac gtggctggtg gaaatttaaa aagccacgag atcaaagaaa
     3901 atatagtcat aaaaatgaat ggaaagaaga tctattggct tatctaagcg aaaaaagtct
     3961 tgctagtgag ccttatttga acctgtcaaa aaaagaattg gcttcacaac taacgatgcc
     4021 caagcgaaca cttgataaga tcttaaatga gttacgagag gagaataaag tcttctacaa
     4081 ggtaacacga ggaagaaatg gcggaatgat cattgcttca gtcaaaacgt tgttcgcgag
     4141 ggttattcaa ctaagtaaag aaaagagact agattattca acaaggatca cagaggtatt
     4201 tggactcaac gagagcttag tagaagagac atttagacaa ttatcaaccc ccttgaaccc
     4261 tcttaaagaa gtgaatcttt ttgaagtaga tacaggttga aaaataaaag gtgcaaattg
     4321 ccttatacaa tatatctatg atacttctgt aggtgttgct ccctttgcct agctacgtgt
     4381 aggtggtata cttataactg cgtatgcagt cttatgtatc atggaggaag ttgtatgtcg
     4441 ttaaaaaatt atgtctattc acatcctgtt aatgtgttta tcattggtcg tttgggatta
     4501 tctgtggaag tgttctgtga gctttatggt tttaagcagg ggactttgtc ttcttgggtt
     4561 accagggaaa aaacagttgc ttctttgccg attgagtttc ttcatgggtt gtccttagct
     4621 tctggggaga ctatggatca ggtatatgat tgtttgtgtg tgttagagca ggagtatatt
     4681 gagtataaaa tagctaacga gttaagaaaa aggaagaagg gttctgttgc aaagttttaa
     4741 ataaagaata aaatccctta cggtatctat gatttaagct gggattccca ataatacctt
     4801 gatttcagta cagaccgaaa acccgaagag agtgccttct tttcgggttt tcttatataa
     4861 tcctcggatg gcttccat
//
LOCUS       DAFELK010000111         4806 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFELK010000111
VERSION     DAFELK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.119"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(52..1200)
                     /gene="nagA"
                     /locus_tag="LP433_002818"
     CDS             complement(52..1200)
                     /gene="nagA"
                     /locus_tag="LP433_002818"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBL2006919.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1276..2112)
                     /locus_tag="LP433_002819"
     CDS             complement(1276..2112)
                     /locus_tag="LP433_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006920.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2296..3513)
                     /locus_tag="LP433_002820"
     CDS             complement(2296..3513)
                     /locus_tag="LP433_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2006921.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3662..3841)
                     /locus_tag="LP433_002821"
     CDS             complement(3662..3841)
                     /locus_tag="LP433_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006922.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3896..3979
                     /locus_tag="LP433_002822"
     tRNA            3896..3979
                     /locus_tag="LP433_002822"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3930..3932,aa:Leu,seq:gag)
     gene            complement(4219..4797)
                     /locus_tag="LP433_002823"
     CDS             complement(4219..4797)
                     /locus_tag="LP433_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006923.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1460 a         1001 c          775 g         1570 t
ORIGIN      
        1 accttaaaac caaacttaag aagtttagtt ttaaggttaa cttaaattat attatgcgtg
       61 gaaacgttcc acgccatcta gataagttgc ttccaatgtc atatcagggt tcaatacgat
      121 aaagtctgca tcgcgtcctt gagcgatttt tccacatgta tcatcgattt tacagctgat
      181 tgctggaatc agactagcca tcatgactgc ttgttctggt gttgctaatc cccagtctac
      241 aacattttta attgcttctt tcaatttcaa tatacttcca gctaagttgc cagattctag
      301 acgtgctgtt ccttctttta ctactactgg aaattcgcct aaattgtaat ttccatcagg
      361 catcccaccg gccatcatac agtctgtaat taatgcgaca tgatcatgtc ctgctttttc
      421 cattaggatt cccgcagcat ttggatgtac atgatggcca tcacaaatca attcagaaaa
      481 gacatgttct aaagataata acgcacccac catacctggt tcgcgatgat tcaatccacg
      541 cataccattg aaagcatgga caaatacact tgcgcctgct tcaacagctt tttgcgcttc
      601 ttctagtgta gcattactgt gtcctagaga aacaactact ccttcttcag tcacttgttt
      661 gacaaactct tctacacctt gacgttccgg tgctaaagca atttttttga ttaaaccacc
      721 tgaagcttct tgccattcat ggaaagtatc caaatcagga tccccgaaat aacttgggtt
      781 ttgtgcccct ttgtgttctt ctgtgaagaa aggaccttca aaatagattc ctttgatttt
      841 agctcctggt gcttcctgat acattttgcc gattgtctca gctacatctt ttaaacgttc
      901 tttgcttgac gtcaatgttg ttggtaaaaa tgaagtcact ccacaagata acagaccttc
      961 agacatcact ttgatgcctt ctgcatcatt atccattaca tcatgattca tatagccgtg
     1021 aatatgtgta tctaccaaac caggagcaat ccatttgccg ctttggtcaa tgatgttgac
     1081 ttctccctca ggtagttctt tggtgtattc accaaaaagt ccatcggtaa tttcaagata
     1141 gcctgcatgt ttgacacctg acgctaaaaa gaatttgtca gcatagataa aagttctcat
     1201 tctattctct ccctttgttt ttctacctct aaagtactct tatttagaga agaagtcaag
     1261 aatggtctac accatttaca aattttttga aatttgtttc acagcttgtg ctaagccttc
     1321 atagaatgct gctctttctg gttcttcttt acgcttgtat attaagcttt taagcacaaa
     1381 taaatcattg aggtaatagt agctattctt ctcttgagcc caatagattc cttgattcac
     1441 ctgttctaac gcttcgtcga tttcattttg atggaataag aaatttccat aattataaaa
     1501 aatttgcgaa aattcacttt ttgatcgttc atcagctgat tgatgcagca gttggatgct
     1561 tcgactcaaa tagtagcgtg cttcagccgt ttttcctgcc acaccatata tttttccgat
     1621 acaactaatc agttgtattt ctgtgtcaga aacatggatt ctttcttttt ggctagagta
     1681 gcttaatgct tctttcaaat aataaaggga ctgagagata ttttgacgca acgtgaattc
     1741 gcaaacaccg agataataat aatagcgttg aaagtcagtt gcttgataca gattttcaga
     1801 aatatcagaa gattttagta cttgttctaa cttccgataa tcacgttttt ggaaacaact
     1861 atccaacagt tcaaataatt tatcgtttgt ccgagtagtt tttcgagaga gattcatcac
     1921 atgatcaatc gttaccccta gccgttgaca aatctgcatc atcaccaata cattcggcag
     1981 ttcctcatta ttttcgatcc gacttaatac actttgtgaa caaatatcat gcgaaagcat
     2041 tttttgcgtc attttttgtt cttttcgaat ctctttaatg atcgttccaa aggactcgat
     2101 taacgtttcc ataagtatcc tccccaaaat atgcgtattc gcattctatt cgtattttac
     2161 tttaggaagt cgcaaacttc aagaaaagac ttgcaactaa ataatatact ttagttattt
     2221 aagaaaactc cactagaaag agagcctcag tgtgtttgtc tgtggccctc ctactgaaaa
     2281 atttggtttt taaaatcatt tttggcgata ggttgctagg aattctctca ttttcttagc
     2341 tgtttgtttc aaatcatcca ttttaggaag ataaacgatt cgaaaatgat ctggctggtt
     2401 ccaattaaat ccaccaccat gtacaagtag aatatgatgt tcatgtaaaa agtccaaaac
     2461 gaatttttca tcatccaaaa tattgaatcg ctttgtatca atttttggga atatataaaa
     2521 agcagctttt ggttttacgg ctgaaagacc aggaatatca ttgattgcat tatagatata
     2581 ttctctttgt tcatagatcc ttccgcctgg caggagcagc tcatcgacac tttgataacc
     2641 gcctagcgcg gtttggataa tttgctgaga caatacattg gaacacaaac gcatggagga
     2701 caacatattc agcccttcta tatagccttt gacgtgtgac ttatctccac ttaggaccat
     2761 ccagcctact cgaaatcctg ctacacgatg agatttggat agaccgttca gcgtaacaac
     2821 gaacaaatca ggcgctaatg tagcaatcgg aatatgttct agaccatcca tcactaagcg
     2881 atcatagatt tcgtcggaat aaataatcag gttattttgt cgagctactt caacgatttc
     2941 ttctaataat tcttttggat aaagtgcccc agtaggatta ttaggattaa tgataacaat
     3001 agcttttgtc cgactcgtta tttttgattt gatatcatca atatcaggat accattctgc
     3061 ctcttcatcg caaatataat gaacaggtgt gcctccagct aatgcaatag aagccgtcca
     3121 caacggatag tccggcattg gaaccagtac ttcatctcca ttgtccagca acccctgcat
     3181 acacatcgtg atcaattcgc tcactccgtt gccggtgtag atatcattga tcgtcacatt
     3241 cggaaaatgt ttcagttggc aatattgctc aattgctttt ctagcagaaa agatcccctt
     3301 ggaatctgag tagccttctg agtcacgggc attcatgatc aaatcacgaa tgacttcgtt
     3361 tggtgcttca aatccaaaag gtgcgggatt tcccgtgttc aattttaaaa tactaatgcc
     3421 ctcttcttgc atccgctccg cttcttctag aacgggaccg cgaacatcgt aactgacacc
     3481 ttctaatttg ttggattttt caaattctct catcacttag ccaatccctc atttcaaaaa
     3541 gttagaactt tccaaatttt ttgttattta ctatttcaat atcatactcc atcctagaaa
     3601 attttgccac ttatttagga aaaacgtaag tattaaaaaa acacaaacaa gcgttgagaa
     3661 cttaattgtc atgatagtca ttccatagat tcgctgccca atccattgca attccacaaa
     3721 tgattcctag cataaaacca agcaaaaaac gtccgaatgc aagtccaatc aatacaccta
     3781 agatcattcc cagtcctgaa aattctccgt catatttctc catcttaata agtcctccca
     3841 tttttgagct tgacaactat gtaaaacctc gctatcatta gtgtgttatt attacgcaga
     3901 tgtgttggaa ttggcagaca agcatgattg agggtcatgt gagcgttagc tcgtgtgggt
     3961 tcgagtccca tcatctgcac tacaactcgt gaagttaatt ttgcttcacg agtttttttg
     4021 tttgaacgtt tctttatgcc attatataca tatcactgta tcctttacaa aaagaacgta
     4081 caatcatgta aacagcctga ggtgagtata tgaaggtcgg aaacaagcta ctcgtagaaa
     4141 cttgcaagtg ttaaaacaat taatcgaaaa acgagtaaaa tccctcacct aatactaaag
     4201 cgagggattt tttgtatatt atctgtttat caccgttatt ataaaggtac aaataccaag
     4261 cacggttaat ccaaattgca taaattcatt tttttgtaca ctcatgcttt tcattagctc
     4321 tttaactgcc attagtacta agatggcgat aacaacataa agtatatagt acgtccgcat
     4381 tccggaagcc catactgtgg gagaaaatcc cataattaac cttgaacaaa atcccattat
     4441 catcaaaata actaaaaaaa tagaagtttt cttattgtca aaacttaaat aaattccaac
     4501 aattaaacat agtaataatg ccaagactac taaagtagct atccaagtac ctggataaaa
     4561 aagtgacagt ttcgttccta actctgtaaa gagattattc aggttactac tactccaaat
     4621 cattgccctt ttatttccat tgacgtaagt aaagctttga cccattgtat taccaaaata
     4681 aataatcagg tttaagaaaa acggtaatgc agtcaatata cgcacataat agttttgaca
     4741 tttcctatat gttagaagga aaattaagaa aaatagcaat aaaaataaga tattcatgtc
     4801 taaaaa
//
LOCUS       DAFELK010000112         4595 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFELK010000112
VERSION     DAFELK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.120"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(448..978)
                     /locus_tag="LP433_002824"
     CDS             complement(448..978)
                     /locus_tag="LP433_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBL2006924.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            1083..1634
                     /locus_tag="LP433_002825"
     CDS             1083..1634
                     /locus_tag="LP433_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2006925.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(1787..2260)
                     /locus_tag="LP433_002826"
     CDS             complement(1787..2260)
                     /locus_tag="LP433_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2006926.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            2398..3870
                     /locus_tag="LP433_002827"
     CDS             2398..3870
                     /locus_tag="LP433_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL2006927.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            3867..4577
                     /locus_tag="LP433_002828"
     CDS             3867..4577
                     /locus_tag="LP433_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBL2006928.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         1438 a          835 c          881 g         1441 t
ORIGIN      
        1 tttttgctgg gagcattatt tcattttgaa gtcactaatt taactgtgtg aatatgcagt
       61 tgttacaatc tttgataaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac
      121 ggcaaaatat gaggaactat ttttccattt gtttctctaa tactcaggtc aaaacgctga
      181 tttcacaacc tcttgataaa cggtgttcaa acggctgctt ctcggtaata agcccactag
      241 cctagaaaat atgaaaagct attttctaac tagcgttctt attactcaaa gcataacgct
      301 gatttcacaa cctcttgata aacggtgttc aatcagctga ccctcggtat tagctcaaaa
      361 aacggcaaaa catgaggaac tatttttccg tttctttctc taatactcag gtcagaacgc
      421 tgatttcaca acctctcttt cacaacctta ttttactcgt ttataatttt catcgaagta
      481 ttttccgcta cggatatcat ctggcattcc atcgtatggt tcttcgctaa taacatcttc
      541 attgtctata cctgcatcac ccatataagt gatcgtagca aattcaggaa caagtaattt
      601 tggataagtt tcatattttt cacgagctgc ttccatttct gcgatatgtt cgttttggaa
      661 agtaacagtg atttctggat gttcttcaac ccatttaggg aaaaagatca ttccgtgaag
      721 tttcttttca tttggcataa agtccaatgc cacgtctgtc cctgttggct ctgtccaagt
      781 gattttgaat acgccgtccg tcaatttaac gatatcagct tcttggtctt ttacccaacg
      841 gcctttgacc attccgccat ggatacggta atcaacagta tggtcatttt tggcatacca
      901 ttcatattcc caaccattgt catacgtata gataaagtga gttccaataa aatcttccaa
      961 ttctttaaat tctttcatgt ttaagcatct ccttataaat taaaacatgt aataaactac
     1021 atgttttcga ttactcattt atgatagaat ggatttaaag atttgtcaag gagggaaaac
     1081 tgatggcaag aaaaaataca cttcgatata ttttgttagg gttattaagt aagaagaaga
     1141 tgacaggata tgaattgaat caatcgttca aaaatgaaat aggagaattt tggcaagcaa
     1201 aacatagtca gatttatcct gaacttgcaa aaatggaaga gcaaggaatc attcagcatc
     1261 aagtagagat cacaggtgaa aaattggaaa agaaagttta tgaattaaca gaagaaggga
     1321 aggaacaatt ggcagagtgg attcatacac ccaccaatga actaccggtt aatcgagacg
     1381 aatttgttct gaaattgtat ttcgtcaaag acgtgaatga tccggcatta gtagaaatta
     1441 ttcagcagca gcgtgacctt catgaagaaa aacgacttca tctattagag cgaaaaaaaa
     1501 cgatctttcc tactgaaaaa gaaaaacatg aaaattacgg acactacctg attttagcgc
     1561 atgcgatcaa tcgggaaaca gaatatgcaa attggctaac agatgtatta gaagaaagta
     1621 accgaaaaaa ataaaaaaat atccgaacag tgatggagaa ttcctttcta tatgaaagaa
     1681 acgcagatca ccgttcggat attcttatgt tcaaacaggc cttttttcaa gtatttatgt
     1741 agcatctact tattaaaaag cttggtactt aggagattag tggcgtttag agttctttta
     1801 acaactgttc gtagtcagct ttttcatcga caggaaggag cttgtaagtt aattcgtctg
     1861 tctcgttgtc atgaatgatg tacatcttag cattctcttc tttgaagtta ccgatttgta
     1921 aaatcgtata gcgttcgtcg atcaattcga tatctttgat tgcttttgaa aaaactttac
     1981 ggacatggtg cattttcttt tggcggattt ctgccttttc tgcagctttt gacaaagtaa
     2041 atccgtcatc taaatatttt ttgatcagtt ctacttttat gactgtaggt aaacgatatt
     2101 ttctaggaca attcgcatca gcttcgatcg aacgaatgaa tcccttttgt tcccaatacc
     2161 ttaattgacg tggagacaca cctacgatat cacttaattc actgatgcca acaaccaatt
     2221 gatcattttc caacaaacgt ttaagggaag ccccaaccat ttttgtcact ccttttgtcc
     2281 tcttgcttcc cttaattata tccgtattaa cttatgtgtc aagtaggttg acaaatagcg
     2341 aatttaggac taaagtattc tagtagtttc agaaaaaatt cagaaagaag gagaaatatg
     2401 agtaacaacc aacccgtaga tatttacgga aaaccatata atcggacact tttagttgtt
     2461 gtcttattaa ttggtacatt ttgtaccgtt ttgaatcaga ccttattgac gacagctttt
     2521 cctacattga tgaaagcttt cgatatttca gcgtctgatg tgcaatggtt aacgactggt
     2581 ttcttgctag tcaacgggat catgatccca ataacagcat ggctgatcaa taaattcagt
     2641 tcaagaaatt tatatctttc tgccatgacg atctttttga tcggaacgat tacttgcttt
     2701 acagcaccta attttagtac attactaatc ggtcgtttga tccaagcttg cggtgtggga
     2761 gtatcgatgc cattattgca aaatatcatg ctatctattt tcccgccaga aaaaagagga
     2821 tcagcaatgg ggatgtcagg gatcgttatt ggacttgctc ctgctttagg ccctacatta
     2881 tctggttata tcattgataa ctaccattgg cgtgacttgt ttggtatggt actgccaatc
     2941 gttgttcttg tcttggtttt agcattcttc ctaatgaaaa gtgttattcc attgtcaaat
     3001 cctagcattg atattttatc cgctatttta tcaacgattg gattcggtag tttactttac
     3061 ggattttcta gtgtaggaga tgacggctgg ggaagcttga aagtaattgg tttcttagtt
     3121 gttggtgtga ttttcatcgc cttgttctca tggcgtcaat tacatttgga acatccattc
     3181 ttggaacttc gtgtattcaa atcatctaca ttcacgattg cagctgtttt agctggtgta
     3241 acaaatatgg cgatggtagg ggcagaaatg gtcgtaccat tgtatattca aaatattcgt
     3301 ggagaatcag cattccattc tggcttgatg ttgttgccgg gtgcattgat catgggggct
     3361 atgatgcctg tgacgggtgc gattttcgat aaatacggcg cgaaacgttt agccatcaca
     3421 gggatgttca ttttgacagc ggcaactgca ccatttgctt tcttgacaaa aacgactcca
     3481 gttttatata tcgtgatcct ttatgcgatc cgtatgtttg ggatctccat ggtcatgatg
     3541 ccggtaacga cttctggtat gaatgcattg ccaaataact tgatcagtca tgggacagcg
     3601 gtaaataata cattccgtca aatcgcaagc tcgattggta cagctatttt gatcagtgtg
     3661 ttgacgaatg tgacaaaagc aaatatccca agcaaatctg tattggataa tacgccatta
     3721 gcttataaag atcaggcaat caatgccaca ctgtcaggtt accatgccgc gtttatcgta
     3781 gcgatcatct ttgggattct tggctttatt attgcctttt tattgaagaa aaaagaacct
     3841 gttctaatga aagcggggga taatgcatga ttattggagt tttgattgtc agcttgcttg
     3901 cttttgcttt aacgaacgtg ttcgctaaaa aaacatggca aaccttttta tctttgattt
     3961 tcggactaat cttcgtcgct tcactaagtt tgatcgtcgc taatttgtcc aatcactttg
     4021 gaatggaaaa agtaacggaa acaaaaacag aaaaaattgt ttccagtgct gattcccaag
     4081 gagcagatat gcttttgtat aaagctttag ggaatggaaa agaaaaagtg tatctttacc
     4141 gaacaaatga aaaacaagaa aaaccaaaag caactggtac ggataacgaa acaaataaag
     4201 tagaaaagac agacggcgat gctgaaaaag tgacgaaaac tacttattgg gaatacaaaa
     4261 acgacatgta taaattctgg ttcaatattg ctgataacaa tcacgaatat gacagccgag
     4321 tgaatacatt caaaatccca gagacatggg tagaattaag tacggaccaa gcagccaagt
     4381 tagctgaatt agtgaagaaa cagcaaagta cgatggaaag tgaagcaaaa gcttatgttc
     4441 aagacggtat ggtaaaagca atgactgaaa atccaaaaat gagcaaagca gagcaagaac
     4501 aacgtacgaa agccttagct gctgaattcc aacaacaagc attcgcaaaa ttagtgaaag
     4561 aagcaaaagg cgaataatat tttgaacacc atgta
//
LOCUS       DAFELK010000113         4424 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFELK010000113
VERSION     DAFELK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.121"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            690..1658
                     /locus_tag="LP433_002829"
     CDS             690..1658
                     /locus_tag="LP433_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2006929.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="LP433_002830"
     CDS             1669..2484
                     /locus_tag="LP433_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HBL2006930.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="LP433_002831"
     CDS             2552..3262
                     /locus_tag="LP433_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2006931.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4424
                     /locus_tag="LP433_002832"
     CDS             3298..>4424
                     /locus_tag="LP433_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBL2006932.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         1490 a          661 c          921 g         1352 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaa
//
LOCUS       DAFELK010000114         4415 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFELK010000114
VERSION     DAFELK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.122"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            58..912
                     /locus_tag="LP433_002833"
     CDS             58..912
                     /locus_tag="LP433_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL2006933.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1009..3258
                     /locus_tag="LP433_002834"
     CDS             1009..3258
                     /locus_tag="LP433_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL2006934.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKIPEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3261..>4415
                     /locus_tag="LP433_002835"
     CDS             3261..>4415
                     /locus_tag="LP433_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2006935.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          626 c          805 g         1428 t
ORIGIN      
        1 taataatata aacataataa aacaaaaatt atccaaatct aacataggag ggtggatatg
       61 gaaaattcta tatatttagt aacagaacct aacactcagc tgaaagattg ttactttaat
      121 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
      181 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      241 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      301 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      361 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      421 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      481 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      541 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      601 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      661 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      721 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      781 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      841 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      901 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      961 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
     1021 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
     1081 ataagttaca tttttaagat accggaagat ggtaaattat tgcatttata ttatggtgag
     1141 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1201 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1261 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1321 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1381 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1441 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1501 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1561 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1621 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1681 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1741 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1801 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1861 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1921 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1981 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     2041 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     2101 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2161 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2221 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2281 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2341 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2401 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2461 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2521 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2581 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2641 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2701 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2761 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2821 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2881 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2941 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     3001 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     3061 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3121 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3181 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3241 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3301 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3361 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3421 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3481 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3541 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3601 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3661 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3721 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3781 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3841 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3901 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3961 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     4021 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     4081 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4141 cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc tttagtaact
     4201 tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt tttattggct
     4261 gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt ctaacaagaa
     4321 gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg atcctatttg
     4381 taacattttt tgcgacaaat aaaaaaaata ctaga
//
LOCUS       DAFELK010000115         4264 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFELK010000115
VERSION     DAFELK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.123"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            24..95
                     /locus_tag="LP433_002836"
     tRNA            24..95
                     /locus_tag="LP433_002836"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56..58,aa:Gln,seq:ttg)
     gene            113..197
                     /locus_tag="LP433_002837"
     tRNA            113..197
                     /locus_tag="LP433_002837"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:147..149,aa:Leu,seq:caa)
     gene            452..1327
                     /locus_tag="LP433_002838"
     CDS             452..1327
                     /locus_tag="LP433_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2006936.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1431..2195
                     /locus_tag="LP433_002839"
     CDS             1431..2195
                     /locus_tag="LP433_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBL2006937.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            2182..3624
                     /locus_tag="LP433_002840"
     CDS             2182..3624
                     /locus_tag="LP433_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2006938.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            3635..>4264
                     /locus_tag="LP433_002841"
     CDS             3635..>4264
                     /locus_tag="LP433_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBL2006939.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIY"
BASE COUNT         1378 a          649 c          907 g         1330 t
ORIGIN      
        1 tcccatcatt cgccctttat tcttggggta tagccaagcg gtaaggcaag ggactttgac
       61 tccctcatgc gttggttcga atccagctac cccagttatt atttttaaat ttgccggcgt
      121 ggcggaattg gcagacgcgc tggactcaaa atccagtgtc cgttgaggac gtgccgcttc
      181 gaccccggcc gccggtataa ttatcaatat agcaactttc ttatagagag ttgctatatt
      241 ttttttgttt ttatgtaatt acctccaaat caattcgata caagtattat cataaaacga
      301 gtaaaaaaga tattgataac gcttttatta tgtgttaaac tatttttgta aattatgtag
      361 ggtgctacta ttcaattagg cacgacctaa gaaagggttc tttcttaggt cgttttttgt
      421 ctttaaaaat tgtttggaga caaaaatatg tatgaaggag tctgcaagtt gttttgtttt
      481 atcatataga ggaggtgaat taacggtgta tgtgatgaaa aagctgaatc ataatgctgt
      541 attgatcgat gacgatggaa tagaaaaaat tgcgatgggg aaagggattg gcttttctgc
      601 taaagtgagt aagccatttg atgttgagga tgctgacaaa ttatttgtat tagattctaa
      661 agaaaagatc aaacgattca gtgagatagt ctcgcagatt ccaatcgaat ttatggattt
      721 tgcggaagaa gtgattgaac tgataacagc taggatctcc tctccattag attcaaatat
      781 ctatattaca ttgacagatc atatttattt tgctattcaa cgaaaaagag aagatagaga
      841 tgtcacagca attatgttgc cagaaatgag attcctttat ccaaatgaat atgatatagc
      901 agtagaagtg gtcgagcgaa tcaatcatcg atatcaaacc gagttagggt caaatgaagt
      961 aggattcatc actatgcata tcattaatgc tgagctagga gagcctaata gtttaaagag
     1021 cttaaaaata gtagaaatga cgaccacgat tttgtcccat ctagaaaaat cctattcaaa
     1081 cgtttatgat aaagaatcac tgacttatca tcgcttaatg gttcatatca aattcctggt
     1141 taaacgcttg atttatcagg aagaaacgcc agtagaaaat attggttttt ttactgaaac
     1201 atttaaacat agcaaagcgt attgtacagc actaaagatt aaagatatca tcgaacagca
     1261 atttcaactt gccattcaag aaaatgaaat catctatttg gcaattcatc tagcaagaat
     1321 ctattaaaat aagggcgtaa ctatctatag gcgcaaccaa atgacacata gtaaatggac
     1381 tatgattatt tggttgcgcc tattttagta gaaaaaagaa ggagaatgaa atgggaaaag
     1441 tgatttttaa ttcggatgat tttggctata gccatggtgt gaattatggg attatggatg
     1501 cttatcagcg aggaattttg acatcaacta cattgatggc aaatatgccg ggtttcgagc
     1561 atgctgtgaa actaagaaag gaaatgccta ggctaggtgt aggagtccat ttaacattga
     1621 cgtgtggcaa accactcctc aaaactgtcg atactcttat cgaaagcgga gagttcagat
     1681 ccttatctta ttatcagcat ccatttaaca ttgacaaaga tcaactgtat caggaatgga
     1741 atgctcagat tcaaaaaatt tatcatgcgg ggatcatacc aactcattta gacagtcatc
     1801 atcatactca tactttggat gaaaatcagg aggtagttgt tacattagca aaaaaatatg
     1861 atttgccggt tcggagcaac tttgaacgaa aagatgaagt tcgtcatgtc gattattttg
     1921 agccttgttt cgatgtcgta ggagaaactg atgaaaaaaa acgacaaatc aatacgagtg
     1981 tggaagaata tttggcaagt ttactcatga tattgagaga agataaaacg atcgaagtca
     2041 tgtgtcacgc agcgtatttg gatcaggaat tgttaaatgg ttcaagtttt gtgtatcctc
     2101 gtacccacca agtcgaattt ttaattcatt cagcatttgc tcaaaaagtg aaaaatgatc
     2161 ctttgattga gttagtaaca tatgaggata tttaatagag gaggaataaa aatgaatgtt
     2221 aaatcaaatg tgcagaagct tggaagagcg atgctacttc cagttgcagc gatgccatta
     2281 gcgggattga tcatgcgttt atcagctgac gatatgctga acatcccagt aattggtgca
     2341 gctggaaatg ccgtttttgg aaacttggat atcttatttg ctataggagt tgcaatcggt
     2401 tttgtcaaaa ataaggacaa aggaatacct gcacttactg gttttttagc gattgctacc
     2461 ttgaaaaaag gcttagaaat tatggaccca gaagtgaata tggggatttt tggtggaatt
     2521 atttccggtt tagtagcggc atggacgtat aatcgcttta aagaacaaaa attaccagta
     2581 gttttttctt attttgcggg cgaaaaattc ccattgacta tggtgatgat tctacaaaca
     2641 atcgcagctg tttttttggg ctttatctgg ccgctcatcc aaattgggat tgataatttt
     2701 gcaaaactgc tcgttgatat gggagcatta ggtgtgggga tatttatgtt tttgaatcgt
     2761 ttgctgatcc cctttggact gcaccatgtg ttgaatacgt atatttatta cgatttagga
     2821 agctatacat ctcctagcaa ggaagttttc agaggagaga tgacacgctt tatcaacgga
     2881 gatcctcagg ctggactgtt tttatcaggt ttttttgtag taatgatgtt tggtatacca
     2941 gctatatgtc tagctatcta taaagcagct tataaagaaa ataaagagat ggtcaaagga
     3001 atcatgggaa gcggtgcagg aacttcattt attgcaaata tcactgagcc tgttgaattt
     3061 agtttcatgt ttctttctcc tatgttgtac gtgatccatg cactttttgc cggtttagca
     3121 gggattgtct gttacttatt caatatacga attggtttta cattcggagc atgtattgtt
     3181 gattatctca tcaattttcg aatcgctacc aatgctattt tgattcttcc aatcggaatt
     3241 ttcttttttg ccttgtatta cgttactttt tattatttga tcaataagag aaacattcag
     3301 acattaggac gtgaagctaa ggcagagttt ggcaatgaag taaccttaga agaaacagag
     3361 ttagggttag caagtaaaaa ttatgaatat atggcaacaa aaatgctaca agcgtttgga
     3421 ggaaaagcca atatcctgga tgtctatagt tgtaatacac gcctacgggt agaggtagtg
     3481 gatcccacca tggtcgagga acagcgaatc aagcaattag ggataagcgg gatcattaaa
     3541 ccaactgaaa aaaattatca aattatcatc ggcttagaag tgacttatgt tatggcagaa
     3601 ttcaataaat tattagaaga atagaaagga aaagatgatg atgaaaaaac agattatcac
     3661 tatagctgga ggcgggagta cgtatacacc aggaatcgtt caagccattt tgaacaatga
     3721 aaaacggttg ccattatctg aaatacgttt atatgatatt gatgaagaaa gaaatatgga
     3781 tatgtacttg attgttaaat ttatgctgaa aagaaaaggt ttttcaaata ttcgcattcg
     3841 tgcaacggat gatccaaagc ttgcttttac aggatgcgat tttgttttct cacaaattcg
     3901 tgttggagga ttggagatgc gagaaaagga cgaaaagatt ccacttaaac atggattagt
     3961 aggacaagaa acgtgtggac tcggaggatt tgcttatggg atgcgctcaa tcaaaggttt
     4021 attggaaatt gtcgatcata tacaagacta tgcccccaaa gcatggattt tgaattatac
     4081 aaatccagag tcgatcgttt ctgaagctgt tcgtcgtaaa tatccgaatg taaaaatgat
     4141 taatgcctgt gatatgacta tttcaattga agaaacgatt gcagtgaatt acggttatga
     4201 tcgtaagaat tggatcgtta cgtattatgg tttaaaccac tttggctggt atacatcgat
     4261 ttat
//
LOCUS       DAFELK010000116         4105 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFELK010000116
VERSION     DAFELK010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.124"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..543
                     /locus_tag="LP433_002842"
     CDS             <1..543
                     /locus_tag="LP433_002842"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL2006940.1"
                     /translation="ISKENLLNQDFSTETICEKWAADITYIPTKKNGWCYLSSIMDLH
                     TKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNK
                     IRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIH
                     SSIHYLTPQEFEELAKEKMA"
     gene            complement(1016..1588)
                     /locus_tag="LP433_002843"
     CDS             complement(1016..1588)
                     /locus_tag="LP433_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006941.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1604..2209)
                     /locus_tag="LP433_002844"
     CDS             complement(1604..2209)
                     /locus_tag="LP433_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBL2006942.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(2330..2587)
                     /locus_tag="LP433_002845"
     CDS             complement(2330..2587)
                     /locus_tag="LP433_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL2006943.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(2580..2849)
                     /locus_tag="LP433_002846"
     CDS             complement(2580..2849)
                     /locus_tag="LP433_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2006944.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(2980..3159)
                     /locus_tag="LP433_002847"
     CDS             complement(2980..3159)
                     /locus_tag="LP433_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006945.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(3540..>4105)
                     /locus_tag="LP433_002848"
     CDS             complement(3540..>4105)
                     /locus_tag="LP433_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006946.1"
                     /translation="EQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEK
                     YIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDD
                     YYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYT
                     YDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         1226 a          830 c          622 g         1427 t
ORIGIN      
        1 atttcaaaag agaatctctt aaatcaggac ttttctactg aaacgatctg tgagaaatgg
       61 gcagctgaca ttacgtacat tcctactaag aaaaatggtt ggtgttactt atcttcaatc
      121 atggatttac acacgaaaag aattattagt tatacatttt caaaacgaat gactgtggat
      181 tgtgtcattc aaacattgaa taaagcaaaa atacattatc acattccaga aggaatgatt
      241 ctacacactg acttgggcag ccaatacaca gcaagagaag tggaacaatg gcttaaaacc
      301 aacaaaataa ggcattctta tagtagaaaa ggaacacctt atgataatgc tggaatcgaa
      361 tctttccatg cctcattgaa aaaagaagaa gtctacacga ctagctactc agattttgaa
      421 gaagcaaatc gagcgctatt tagctacatt gaaggatttt ataaccgaaa tcgaatccat
      481 agctcgattc actatctaac cccacaggaa tttgaagaat tagcaaaaga aaaaatggct
      541 taaccgtctc tactaaaatg tgtccaagat attgactcaa atccagtaat atcacaatag
      601 gaatgctgtt tattatatta gcagcagtgc tgatttttat gatagttatt tggttcttaa
      661 atgaaagatc taaagacaat caacaccgta gggatatgga gataaaatca atagagtcaa
      721 tagattattt atcgataata acactaaaaa agccacgttc ctaaacgtga cttacgctga
      781 acgatatgtg ttgtttggta gacgaacaaa tcgttcatta taaatatatg atggtatcct
      841 aatatagtaa gcgtggctag cataccttta attactttac cttttacagt taccatacac
      901 attttttgag cagaaatcaa gtaaataaaa aaatattata tttcacaaca tgctaataga
      961 ctcatatcta gaacgcatta agtatttacc tgtctggttc gctgagactt cttttttaac
     1021 tttcttcaat tttcttcttt attctaaaaa gcgtactgcg actgaaaccg gttatagctt
     1081 caacttcctt atacgattta cctgaagtaa gcagttcata tgcgtgcctc ttcttcggtg
     1141 tgattgttgc tttcggacgt ccttctctga aattaggatt attctttctt gcaaacattt
     1201 ttccttcttg ggtacgttcc acaatcatat cacgttccat ttctgctaca ctcaacaacg
     1261 tccgtgtcac cattcgcccc atggacgtat tttcaatcgt tcctagattc aaaaccttga
     1321 tcgttacgtt atcatcgagt aaaggttcaa tgatctctaa tgcttctctc gtgttacgag
     1381 caaatcgatc aagcttcgta acaactattt catctccagg cttcagacca gccaacagct
     1441 gattgaattt tggccgatcc cgttttgtac ccgtaaattt ttctgaaaaa atattcttct
     1501 tctctacgcc gttctcaagc aactgttgaa tttgttcttt tgtactttga gaagcggttg
     1561 agacacgtgc atatccatat ttcgtcattt ggtccaccta cttttacaaa tcatctatcg
     1621 tatactcaga atacccttca tagaaatagc tgacatcgat tcctttcata tataactcgc
     1681 gatcgtcaat tttatcagtc agagcattgg aaattagata gcgtatttcc aaatcgttta
     1741 tgggacttcg ctccattgca gaaagatagt ctgctttatc gattaagttc caatctacaa
     1801 ctttttgcaa ttcttccttt aaaatgagat ccagccaaat tctagtactt cggccatttc
     1861 cttctcgaaa tgggtgagcg atattcatct ccacatattt cttgataatc tcttcaaaag
     1921 aagtttgtgg catctgatca atatgctgta acgaatgttc taaatacata actggtgcaa
     1981 atcgaaaatt tccttttgca atattgaccg atcggatttt tccggcaaaa tcgtaaatat
     2041 ccgaaaatag aaattcatga atttcagata aacctttaaa tgtaccaact tcgatttcat
     2101 ttatttttcc acaatcgtac aattctttcg ctttttgttt actgagtttt tcttcaacct
     2161 tagccaactc aacttgattg gttaatccca atttattctc taaaatcatg cgaaatctcc
     2221 ttaactttat gacataagtt tatgaaacac tctcaacccc attatatcgc gattttgttt
     2281 atgtgtcaaa aactattaag tttctgaccc tttccttact tccgattggt taatagtgat
     2341 cttttgcaga ataaataaat atcgtttcat tttcaactct atatatcagt ctatgttcat
     2401 ctgtaattct tctggaccat tttccagata aatcatgctt taatggctca ggttttccta
     2461 atccagcaaa gggggaacga tcgatatctt ttattaactt gttaatcttt tttatattgc
     2521 ttttgtttcc ttgctcatgc caataaagat aatcatccca agcatcatca gaccaagcct
     2581 taatcatcag attcaacctc gattaagtca tgtgttttaa atgcaccttt ggagaattgt
     2641 tcatctcctc gacgaatttt ttccatgacg taattattag aaagtgttct caacgtttct
     2701 tgcatagaat cataatctct ttttgataat acaacaactg tatcttctac atctttactt
     2761 gttacaataa gtgtttcagc atcctcatta acttgtttca tataactacg taaattttgg
     2821 cggaaatttg aataagctac tgcttccatt cctttcaccc cttatttatt tctataaaac
     2881 aattgtacat tatattgtac aattaagcaa atgattaata ttctaacttc ttataattaa
     2941 aagtgctatc acttttagtt tttaggataa aaagtgacgt cactttttga gtgctggtac
     3001 ctcaaatcct gctttttctt gggcaatcaa taaatctaac gcaatacaca taatcctgga
     3061 ttcacttttg ccgtacttct gctttagttg ctgcaattct ttttgtctct tttcatccaa
     3121 cgtaacgggt aaccgtttat ttcctattgc aattggcatt agtactctct cctttcatcg
     3181 aaataaccct atgaaaaata tggctgcaat catcttgaat agtagactca caagggctaa
     3241 tacaaagcgc caaaagatca aacaaaatac cagtattgcc aaaaatacta cgaagtttaa
     3301 atgcacagct gcagcatggc gcataagtat ttcgccaaca aataggacta acaatagagg
     3361 aatgatttta ttcatatgga tctccttctt tctcttaggt tatcgggtgt tgcccgctta
     3421 tttcgcacca cctaagcggc gggggcggtt ggagcgattg gtgcgaaata agaaccattc
     3481 ccttagttac taggtttttt gtccttattt cacacattct cacttttcgg tataaatgat
     3541 tattgccttt ttttcctttc aaatcgttga tatggcattc gtttacggtc aagttcattt
     3601 tggatttctt ctgtatcgtc gtaagtatag gtgtctaaaa aatcagttaa agtcgtgtac
     3661 cagtcgtcgc ctgggttatc tacttcttct acatattccc tcaaaaatgc ttcgggtaca
     3721 gcgagttcat aatccattcc cattaacacg atagattccg ttccacacgt caaaaatcta
     3781 gtaaatacaa ggtaataatc gtctatcgtc gcatctttgc tgtttagctc ttccatttct
     3841 tcttccatta attccatgct ctcaaaaatt gaataatatt ctgattctga gtaatagtgt
     3901 ttcctgcaaa tcgtgtagct gacaaagttt tcgaccagct cactcctttc taggtaaaca
     3961 ttcatgatgt atttttctgt ttctagtcgt agaagctccg ttcctttttt taccgtttca
     4021 ggacgacgtt tatacacgtc taaacgatta tggctgactg tgaccttcgt ttgactcgtt
     4081 tcactttcca aatacaattg ttctt
//
LOCUS       DAFELK010000117         4100 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFELK010000117
VERSION     DAFELK010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.125"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            137..310
                     /locus_tag="LP433_002849"
     CDS             137..310
                     /locus_tag="LP433_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006947.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            950..1423
                     /locus_tag="LP433_002850"
     CDS             950..1423
                     /locus_tag="LP433_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBL2006948.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1432..1659
                     /locus_tag="LP433_002851"
     CDS             1432..1659
                     /locus_tag="LP433_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006949.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2295..2666
                     /locus_tag="LP433_002852"
     CDS             2295..2666
                     /locus_tag="LP433_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006950.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2922..3164)
                     /locus_tag="LP433_002853"
     CDS             complement(2922..3164)
                     /locus_tag="LP433_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2006951.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3196..4098)
                     /locus_tag="LP433_002854"
     CDS             complement(3196..4098)
                     /locus_tag="LP433_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2006952.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
BASE COUNT         1187 a          724 c          639 g         1550 t
ORIGIN      
        1 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
       61 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
      121 aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
      181 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
      241 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
      301 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
      361 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
      421 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
      481 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
      541 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
      601 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
      661 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
      721 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
      781 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
      841 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
      901 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
      961 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     1021 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     1081 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     1141 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     1201 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     1261 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     1321 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     1381 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     1441 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     1501 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     1561 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     1621 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     1681 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     1741 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     1801 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     1861 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     1921 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     1981 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     2041 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     2101 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     2161 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     2221 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     2281 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     2341 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     2401 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     2461 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     2521 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     2581 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     2641 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     2701 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     2761 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     2821 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     2881 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     2941 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     3001 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     3061 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     3121 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     3181 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     3241 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     3301 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     3361 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     3421 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     3481 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     3541 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     3601 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     3661 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     3721 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     3781 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     3841 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     3901 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
     3961 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
     4021 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
     4081 tttgttattg ttattcatgg
//
LOCUS       DAFELK010000118         4034 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFELK010000118
VERSION     DAFELK010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.126"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            73..234
                     /locus_tag="LP433_002855"
     CDS             73..234
                     /locus_tag="LP433_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBL2006953.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..1530
                     /locus_tag="LP433_002856"
     CDS             253..1530
                     /locus_tag="LP433_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2006954.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="LP433_002857"
     CDS             1540..2196
                     /locus_tag="LP433_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2006955.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="LP433_002858"
     CDS             2196..3572
                     /locus_tag="LP433_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2006956.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3702..>4034
                     /locus_tag="LP433_002859"
     CDS             3702..>4034
                     /locus_tag="LP433_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2006957.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1612 a          440 c          704 g         1278 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catc
//
LOCUS       DAFELK010000119         3911 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFELK010000119
VERSION     DAFELK010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.127"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            159..2258
                     /locus_tag="LP433_002860"
     CDS             159..2258
                     /locus_tag="LP433_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL2006958.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            2454..3317
                     /locus_tag="LP433_002861"
     CDS             2454..3317
                     /locus_tag="LP433_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL2006959.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            3422..3895
                     /locus_tag="LP433_002862"
     CDS             3422..3895
                     /locus_tag="LP433_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL2006960.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
BASE COUNT         1553 a          654 c          791 g          913 t
ORIGIN      
        1 aagcttgaga ctacgcagtc tcaagctttt ttttctatag gaaggaaatt cattcattat
       61 ttttaagtaa atcctaaaaa taagctattg gcgtgacgta tagaatatga tagattaaat
      121 ggtagcgtaa acctagtaaa ggagccgatc gctaagtgat gaaaaaatgt ccaaattgcg
      181 gatcgaaaaa aatggagcag aatactatct gtccagactg cggtcatcaa ataactgcag
      241 aagatcagca aataaaagaa tcaattgaag aaacaaatac agatgcagct atgcaggata
      301 aatcaactga agatgcagtc tttcctgata cagaattaaa cgatccaatc gaatggtcgg
      361 aattgaaaga tttacctcta gaatctgtaa tggaattatt cgaaaaagca gaaccagaag
      421 acgaagaacc acctgctcac gatcaagtaa ctaatataga gaaaaatgaa cagaagaaag
      481 caactgttca tgagacttcg gaagaatcag gaaagaatca agaagaaacg cttgaatcaa
      541 aacaaaaaag aagagtagct gaactgaaag aaatcgtcga taatgaggaa gaaaattcga
      601 tactatccgc ttatatcaaa gcacatcgtg aagatacaaa agaagagcac gcgaaagagc
      661 tgctcaaaat gatcagtgaa aaaattgcac aggaaaacaa agtagagcca gaaaaggaac
      721 aagaaactga aaaagactct gatagagaaa acgccacagg taaagaaaca gtaaaaataa
      781 aagacgtaaa aacggatatc acagaaaaaa ctgaagtatt tactgaaaaa caattagaaa
      841 aggaaaaaac gaataaactg ccggaagcag agaaaaaaga aatactcgaa aacacagaca
      901 aaaagtcaac agagcccgat gaaataaata gtgaatccga tgctgaaaat caatctgtaa
      961 gcaaagaggg tactgatctt gaagcaaaaa tagaaaaaga agagaaccag cctaagctgt
     1021 ttgaagcaga agcgaaatca ataacaatcg tgccagatac tgaaaaaaca catcaagaat
     1081 caaacttaga aaaaacagat ccagataaag cgcaaaagaa aaaatcaaaa aaagtacctt
     1141 atctcgtttt agcagcagta cttctactcg gtggaggaag ctgggcttat tatgaccatc
     1201 atcaaaaagt agaagccgaa gtagcagcag aagcaaaaag acagcaacaa atggaagaac
     1261 ttcatgagaa acttgctgcc ttttatacag atgatcacca tcaatttatt cgtgcagata
     1321 tgattcatca agatttatca aaactaaaaa atgatttatc cagtcttaag aatgaaaaag
     1381 gatattcaga gttagaaaca acttaccaag atatccaatc taagatccga gatatccaaa
     1441 aagtgaatga gtggttcata gcacctgcca tcgtcgatga tcatctagca gatgacatca
     1501 agttgaaagc agataaagag atccaagcaa tcgaaacgga taacacagat tttggaaaat
     1561 tgattcaaca agcacaaaca gaagctaaaa atcaatatgc tgaattgcaa acagctaaag
     1621 aaaaaacagc tatagtcttt aaagacggaa aagtagtgga ttcagcaaca cgcgaccaat
     1681 acaagacggc aaaagaagca gtagaaaaag tgaaaaatac agatctatct gctcagttga
     1741 atgaacaatt gaaacaagta gataagatgc tcactgataa agagaaaaaa gaagaagagg
     1801 aaaagaaaaa agcagaagaa gcgaaaaaag cagctgaaga acaagcaaaa caagccgctc
     1861 aagcagcagc tgcagctcaa gccgctcaac aagctgcggt cgcacaagca gcacagcaag
     1921 aagcggcatc ctcgacccct tcctcttcaa actcagcgaa tcagccaatc aaatctgcca
     1981 gagcaagtga tattgccgat gcatctaatc cagcatggac gtgggcacca ggtgtccaaa
     2041 gcaaagtgat tgctacatgt atccaacgtg gatatatcgt tgaaggaggt tacagattag
     2101 aaaaagccag aatcgaaaat ggggaaggct attataatct atatgccact tcaacaaaat
     2161 ctgcattgat gaaaggcatt ggagaaagtg ctttgccatt ttacatcgta accatcaact
     2221 gtaaaactgg atggttcgga ggaaatggga gcaattaatt ttaggcaaat gaaagaggct
     2281 gtgagcctgc cgtttaacac cgtttattcg aaaaagggga gtatgacaca actgttgtca
     2341 tactcctttt ttcacctttc caaaccaagg ctcagctatt caagtagata acattatgtt
     2401 atgatagcaa agaaatgtat taagaaaacc tttcactata gagggagaaa aaaatgaacg
     2461 atttattagc aactatattt acaggtatta ttattgatga aaatgaaaaa aactactttg
     2521 tccaaaaaaa cggacaaacc tttggcttaa gcaaatcaga aggtgaacac aaaatcggtg
     2581 aagcagttga aggattcggt taccaaaatc aaaaacatga aaatcggatc actacacaaa
     2641 ttcctaaaag ccgtatcggt cattacgctt ttggaatcgt tactgctaca cgaaaagatt
     2701 taggtgcgtt tgtcgatatc ggtcttccag ataaagactt tgtcgtatct cttgatgaat
     2761 tgccgacaat gacagagcta tggcctaaaa aaggggatcg cttgatgatt tcccttagag
     2821 ttgatgcaaa agaccgtatt tggggcagtt tagcagatga aaaaatattc aaatctttaa
     2881 gcaaatatgg aacagaagaa atgaaaaaca aagatgtgat aggaacagca taccgcttga
     2941 aattaacagg tacgtacgtt ttaacggaag atttctatct tgggtttatc catccttctg
     3001 aacgatataa tgaacctcgt ctaggcgagc agataaaagg tcgagtgatt ggtgtccgac
     3061 cagacggtgt actgaatctt tcattgaagc caagagcata tgaagctata tcagatgatg
     3121 cacaaatgat tttaaccatt ttagaacgtt ctgcagatca gcaaatcaac tttacagata
     3181 aatcggatcc agaagaaatc atgaaagctt ttggtatcag caaaggagca tttaagcgcg
     3241 cattaggtaa tcttttgaaa caaggattga ttacacaaga aaacggtgtg acaaaactag
     3301 tcaaaaaatc taattgagaa tcccttgcat gtttttctta actagcttat aataatttta
     3361 attaacatag tgttatatct ttttttattt gtaattatta taaattgttg gggttgagta
     3421 aatggtcatg aatgctattt cggcgatgaa aaaaacaaaa cagcagctac atgaagcggg
     3481 gtttaagctg acaccgcaaa gagaagctac tctgcttgtg cttttggaaa atgagaaaga
     3541 gcatttatct gcagaagaaa tcttcttttt agtgaaaaaa aagagtccgg aaattggact
     3601 tgctactgtt tatcgaaccc ttgaaatctt gacagaattg aaaattgtcg ataaagtaag
     3661 ttttaatgat ggattagccc gttatgattt gagaaaagaa ggcgccaaac atttccatca
     3721 tcatttacta tgcttgaact gcggcacgat cgaggaagta gaagaggatc ttttacttga
     3781 agtggagcaa gtagtagaag aacgttatca ttttttagta aaagatcatc ggctaacgtt
     3841 ccatggaatc tgtcaggaat gctatgaaaa agaaaaaaga aaccagtccg tctgagtgtc
     3901 tagacggctt t
//
LOCUS       DAFELK010000120         3865 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFELK010000120
VERSION     DAFELK010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.128"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..665
                     /locus_tag="LP433_002863"
     CDS             <1..665
                     /locus_tag="LP433_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006961.1"
                     /translation="AYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQFIRQNL
                     TMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMYLFEVGF
                     ILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHTSIHEVT
                     VKGIRSTLKDGQETKTIDQRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKPYVLGKV
                     VI"
     gene            709..978
                     /locus_tag="LP433_002864"
     CDS             709..978
                     /locus_tag="LP433_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006962.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1210..1506
                     /locus_tag="LP433_002865"
     CDS             1210..1506
                     /locus_tag="LP433_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006963.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1508..1930
                     /locus_tag="LP433_002866"
     CDS             1508..1930
                     /locus_tag="LP433_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006964.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1949..3541
                     /locus_tag="LP433_002867"
     CDS             1949..3541
                     /locus_tag="LP433_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006965.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            3562..>3865
                     /locus_tag="LP433_002868"
     CDS             3562..>3865
                     /locus_tag="LP433_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006966.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVNGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKS"
BASE COUNT         1518 a          554 c          757 g         1036 t
ORIGIN      
        1 tggcctatta cttgttaagt gagccaaaac agatcgcggc gtcaaatatt ttcacggcag
       61 taatgacatt aatgtgtgtc atgtgctttt ctatttttag ttacttactc gtccaattta
      121 tcaggcaaaa tttaacaatg agtaaacttt tcaaaagttt attggactta cttatcttag
      181 gcagtatgtt aacgactcta acagatcggt tcgaacaatc tgaaaaaacg gtagagggga
      241 taaagaactt cttaacgacg attgatcaat ttataaatgg atatatgtat ttgtttgaag
      301 taggctttat tctcactttg tttggttgtg tatttataaa actcattaaa agatcaatcg
      361 aaaaagaaat ggttattgat ctaattccga cgctgagcgg ctatgagtat tacgttgatt
      421 ttggaaagta tgaggagttg atccatacgg atatcgttca cacgagtatc catgaagtaa
      481 ccgttaaggg catcagatct actttaaaag atggacagga gacgaaaaca atcgaccaaa
      541 gaaaagaggt ctacaatttt tataaagttg aagcaagtct acgatatggc attgggaaat
      601 tgaggttaga tgggagtaat attcaacaaa acaaaccata tgttttagga aaagtggtga
      661 tttagaactt cctatgaaag atgaataaat aaggagaatc ttttgaaaat gattcttctt
      721 tacagaattg tgcttatagt tggcacggag ttaaaaatct taaagaagga gcagttattc
      781 aaagtgaaag aacatcataa tcagttacta tgtattaaaa cgggtacgat gaacattcaa
      841 taccgaacag aatatttaga attaacgaat caaactgatt ttttgtcgat tcgagagcaa
      901 cataagcaag aaaaattaat ggctacttat agccaattga ttgatgagtg ggaacaattc
      961 aaggaatcta aaacataaaa ttccatttaa acaccttatt ttttaaagag cataaggaaa
     1021 cgtgacccca cttttaaaaa aagtggttgg ataggctgtg cctatcacgt ttctgaaaaa
     1081 aataaatgac cccaaaatac caatatatag gatagtacaa ggatagcaaa ggatagtaaa
     1141 aggatagagg taggatagcg aaaaggatag gatccttttc actatcctat attatattgg
     1201 aggatattta tgaatgttaa aattagagat ttagatccaa aattcatttc tgaaattgat
     1261 cgaagatgcg ttgaactaag taatcgtaca ggaaataaat ggagtcgtaa tgattattta
     1321 aagctactcg ttgaaaatga ttttgatcgt cctttgatgg aatacaaaca agaaaagttt
     1381 gaccagttat tagaaaagtt ttcagaaatt caaagttata acacaaagat attagaagaa
     1441 tatgttagcc aaaataatcg tattatagaa atcttgattg agcaaaatag aggaagtgaa
     1501 ctttgatatg gcaaaggtta tagacaaaca catttacttt caccaaacac atatcgatgt
     1561 attggatgaa actatttcta ctcatgcaga ggttaaaaac tatagtgaag ctgttcgctt
     1621 tttatgtatg aactatgatc cagaagtgga gaaaaaagta aattccaatc aagcaaagtt
     1681 gaatggaatg agtaaagaaa tttctatttt aaccgaaatg gtttcagaat ttgcggatct
     1741 tcatttgaaa gatacaggaa tattaattgg taaaaattca actgtttatc aagaagcaaa
     1801 agaacgagtg gaaggaaaaa ttaaatccaa tcaaacaaaa aaatattccc ctcagttgaa
     1861 gaaacctgtg aatgaatctg ttcatgccag agtagatcca tttgatccaa cgaagattct
     1921 aaaaagataa aaatgaagga ggataataat gactcaatcg ccttcagtta ttctcacttg
     1981 tcaatttact ttgccgaata aaaagtcatt ttctacttat attgactata ttacaaggga
     2041 acaggctctt gaagaaaagg aacgacgtac gcccgaagaa gaacaggaac ttcaacgaat
     2101 caagaatgct ttagaggagt tttatattcc tgaaggagaa actttttcgg agagtaagac
     2161 gggtaaagaa ttcagtgaaa cgtcgaatga agctcaatcg ttgatggaac atggaatcaa
     2221 ttttgacaag ttagaggaac aagattttac caattatctt tcttatatga cacgtcacta
     2281 tgcgttagaa caaaagaaag aactgacgca aagtgaacaa aaagaatacc aacgcttgaa
     2341 ccaagcaatg aaaaaatatc aaacagaacc ccataaaaaa gcttcaggaa atcttcctgg
     2401 agttttttct atagcttcag acgaagtgaa aggaagtgat ctgaaggaga ttaagcaaat
     2461 cttccaaaga ggacaacaaa aaggctcaat catttatcaa gatgttgttt ctcatgataa
     2521 ttcgtatctt gaaaaaatag gattgtacga tcccaaaaca gatactttag atgaagaagg
     2581 gttaaaagca gctggaagaa aaatgatgga gacattattc gagaaagaac aattgaatga
     2641 aacaggttac tggatggcaa cgattcaccg taacactaaa catatccata ttcattttgc
     2701 agttgttgaa aaagaaaata cgcgtaaacc ttacacggag gttgaaaatg gtgtgagtta
     2761 tatcgtaccg aaaggtaaga gaagacaagc aacattagac gcaatgaaga ccaattatgt
     2821 acatgagtta gaacgttttt cttatgaaaa ggatcgaatg attggtatgg agaaacgaaa
     2881 tttattgacg cggaaaagtg atttgcgtaa caccttaaca aaagtggtaa aagagccagc
     2941 gcgttacgat cgacacgcga tgaacttatt aaatgaagta tataaaaccc tacctgacaa
     3001 acgttcggaa tggaattacg gggatgaaaa acgaaccaaa ctttcaccat acacaagaga
     3061 gaaactcgat gagttaacca aatatgtttt aacaaaagaa cctgaatatc aagaatatat
     3121 acagatttca aaagcattga aagaagaagc aaaaagtctt tatggggaaa gcaagagaga
     3181 atcaaaggat gcagagaaaa atgctctctt tgatttaaaa aagcgcacag gaaatgccat
     3241 cctaacagag ctgaagagac aggatagtca aataaaacca ttaatagaaa gtgttgatca
     3301 gatgcaatct atttacaatg aacgatcctt tcgaacgctt aaacaattgc caacgaatga
     3361 atacaaatat agttacgaag aattcatgaa gcgcaggaaa caattccaac aaagagttgt
     3421 cacgcagcgg agtttgcgtc aattaaatcg aacgattaat gcccatgaag aaaaatacca
     3481 cgcaagtaaa gcatacgaag agcaacaacg aagaattcaa atggaacaag aaagacagta
     3541 aagacagtag gaggaatagc aatgaaacaa tatttagatc aatggaaagt tatagaagga
     3601 tcattaagag aagaacgaat cgaacaactt cctgattgtt tagaaaaaga gcatttgttc
     3661 cagataagag aaatgttgag aaacgaacag tttgatccaa atcaattttt agtcgttgag
     3721 tacccagcta ctggtgtgta ttgttgtaat catgtgaatg gtgaaaaata ttttatcatt
     3781 caagaatatg agggcaagtt agcaccttat tatactactt gggaaatgaa tgaagaggga
     3841 atcaataact ttccatgtaa aagca
//
LOCUS       DAFELK010000121         3634 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFELK010000121
VERSION     DAFELK010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.130"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            148..1479
                     /locus_tag="LP433_002869"
     CDS             148..1479
                     /locus_tag="LP433_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBL2006967.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            1445..1795
                     /locus_tag="LP433_002870"
     CDS             1445..1795
                     /locus_tag="LP433_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006968.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1887..2306)
                     /locus_tag="LP433_002871"
     CDS             complement(1887..2306)
                     /locus_tag="LP433_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBL2006969.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(2307..2651)
                     /locus_tag="LP433_002872"
     CDS             complement(2307..2651)
                     /locus_tag="LP433_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBL2006970.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            3001..3597
                     /locus_tag="LP433_002873"
     CDS             3001..3597
                     /locus_tag="LP433_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL2006971.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          959 a          656 c          655 g         1364 t
ORIGIN      
        1 agtcttcttt aacttttttt tgcaaaatta aaaaaatttg gttaaattca atgggttccc
       61 ttacattttt agttttgacc taaatgatag ttgtccaaat ctttcatttc aagttatagt
      121 taaagaaaat gaaaaagaag gtgtgtaatg gaaaacgaaa ctgacgttat ttatattcat
      181 cctcaaaaac gaatcgtttc acagaaaaga aagtattttt atcttggttt tacaggtgtt
      241 ttttttcttt ttattggctt gctttctaat actcctactg ataattggag tggattgcta
      301 actattctta cctcgccaag caatcttttg acagattatt ttgctttagg tgttttcgga
      361 agcgcattca taaatgtagg gattttgacc ttactttctg tgcttttagc ttatcggcac
      421 aaggtgattt taaacggtcc cttatttgct tcgattctaa cagttaccgg tttctctttt
      481 tttggcaaaa acctttataa ttctatctca atcattttag gtgtgtatct atacgctgta
      541 tttgtcaata aacctttttc tcagtacatc atgatcggac tgtttggtag cgtattatca
      601 ccggtcgtta gttatatcac ttttggtatg cgttttcctt tactgatagg tattttattg
      661 gggaatttag ctggcatagc aattggtata cttcttccgc ccttagctgc tcaaacttta
      721 gttttccatc gtggattcac actttataat attggattca cctctgggtt gattgcgatg
      781 acttttactg ctgttttgag gttattcagc tattcaatcg tcgaaaatac attggttttc
      841 aatgaatatc actttcctct catttggatt atttttggct ttttttcgct gacagtcgga
      901 attggtttct attataattc ctttcggctt tcggggattc gagaaatttt cgattcatct
      961 ggaaaattga caactgattt cattgctaat tctggtattg gtgctacttt gatcaacatg
     1021 ggcttagttg gtctgatgct gtcttcttat gttttgctgg ttggcggtca gttaaatgga
     1081 cctgtcatcg gtgctatttt atctgcggtg ggtttcagtg cttttggttg tcatttaaaa
     1141 aacagttttc cgatactagt cggaatattt attgcttctt tgtttggaac ttttcatgag
     1201 atcaccagta ctggcatgct tgttgcagct gtgtttggga caggtcttgc gcccataagc
     1261 ggtttttacg gcagttttta cggtgtaata gctggtgtgc tacatattgc tcttgtccat
     1321 aacgtcagca ctttgcacgg aggactaaat ctatataaca gtggtttttc aactggtttc
     1381 gttgcaggta tccttgtacc gatactagat aactttaccg ctgtcagaaa ggaaaaaaag
     1441 acacttggaa aaagaattat caaaaagaat catcgatgag cttcttactt atttatattc
     1501 ccatgaaata actgaaatac gtattggagt agaatttgct gaggaagggc ttttcataga
     1561 gatacagggt acggcagaaa ctcagccaga agatttagat gtacttgctg atttgctgaa
     1621 caatcctcgg gaccctagta tggaaatcta ctatcaagaa ctattaggta atccccgaca
     1681 tgatcgggaa gattatcatc tgttaggtag tttgattgat gacgtggaaa tcatgtatgc
     1741 ccagccgatt atcaatatta agatctttcg acgtgcttct cattcctatt attaacccta
     1801 ttttctattt ataaaagact gaatcaaaaa agcagctcct gaaagttcga ttaaaatcta
     1861 ctttcaggag ctgttcaagc ttgacattat tgattttcca atccttcata cacttcatct
     1921 gttacaggtt ctaaaaactc tgaattacca gcagtgatcg ccaaatgttc aaaccaactg
     1981 tcttttgtcg caccatgcca atgtttaatc cctttgtgcg ttacgacgac atctccagcc
     2041 attaatcgtc ttgctggctt tccttcttcc tgataccagc cttctcctcc ggtcacaagt
     2101 aagatttgat agccgtctgt atggacatgc cagtgattgc gacaacctgg ttcaaaagtt
     2161 acattaccta caccaacaga aacttcggga tcattcacta acatattcag atagctttgc
     2221 ccggtaaata cttgagcgta agcttcgttt ttttcacctg ctggaaaaat cacgccattg
     2281 tgtatttctt cgtgttttgt catcatttac gcctctttct tatcttcgct attttcttct
     2341 aaatagattt cttttgctaa actaaaagct gaccaagctt ttggccattc tacataaaaa
     2401 gctaaatggg taatgatttc tgctatttct tcactagtaa tgccattttg cttgccaatc
     2461 ttcagatgag ctggcaattg ttcaaaattt cctcctgaaa ttaatgcaga tatggtgatg
     2521 atactacgct gatgagcaga taattcttct ctggaccata cttgtccaaa taaaacatca
     2581 tcatttaatt ctgcaaattt tggtgcaaaa tctcctaatt gatctcgtcc tgcggtttgt
     2641 ttttctgcca tttctcttat tctcccttca cgactgttag gtgattcaac tatggttcta
     2701 aggcaacttt attttctatt gtttcttcgc atttcatttt aaatgtagtc tttcagcctg
     2761 tccaatgctt agtttattca gtcgatatgc tttttaagca tagttgctaa cgcttttttt
     2821 attttaaaaa aaacaagtta ttaaataagt ctttagttgg atgttttttt gagatcaatc
     2881 ttttatactt atgatgaact tacaaaattg tttgttttct gtcatatcaa aaaatggcgc
     2941 agttagttgc ttttctagta aagtatagtt aacaaagaac ctctaaggag ttgatgaata
     3001 atgaatattg ctgcctctcg aaaactgata aatttcatat ccattatcgg attaggccta
     3061 tcaatcgcgc tgacgattta ttttattaat ttaggtgttt tcaaagattt gaatgcgtta
     3121 agaggattag taggtgattc catcatttta ggaccgatta tttttgtctt catccaaatc
     3181 ctgcaagtag ttattccaat cattcctgga gggatcagta ctgcagctgg tgtcctgata
     3241 tttggccctt atgctggatt tatctataac tatattggaa tctgcattgg ttcgattatc
     3301 atttttctgc tagggcgtcg ttatggaaag ccattcatac tttccatgat tagcgataag
     3361 acatataaca aatatattgg ctggctggat aatcaaaacc gttttgagaa gctgtttgct
     3421 ctagctattt ttcttccagt tgctcctgac gatgcgttat gtttgatggc tggattgaca
     3481 aacatgtcag tgaaacgata tacactaatc attttgattg ctaaaccact gtcgattttc
     3541 ttatatagta tggccttgat ttatggaggt caatatctaa gtggtcttct tggataatat
     3601 ttattttgta aaattagtca ttgattgaca atgt
//
LOCUS       DAFELK010000122         3493 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFELK010000122
VERSION     DAFELK010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.131"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            6..1145
                     /locus_tag="LP433_002874"
     CDS             6..1145
                     /locus_tag="LP433_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HBL2006972.1"
                     /translation="MLINKGDLDDLFRRHLELAINALLQAELTVFLDYEKYDRAGFNS
                     GNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLETTIIQLVQKGI
                     TMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVIFMDATHIPLK
                     RQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRGLEEVLLVVTD
                     GLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLVYQASSKEEAN
                     NQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEGFNKQLKKYTK
                     RKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            1445..2137
                     /locus_tag="LP433_002875"
     CDS             1445..2137
                     /locus_tag="LP433_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL2006973.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            2565..2957
                     /locus_tag="LP433_002876"
     CDS             2565..2957
                     /locus_tag="LP433_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006974.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(3130..3312)
                     /locus_tag="LP433_002877"
                     /pseudo
     CDS             complement(3130..3312)
                     /locus_tag="LP433_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
BASE COUNT         1354 a          446 c          548 g         1145 t
ORIGIN      
        1 tggaaatact aatcaataaa ggtgatttgg atgatttgtt tcgtcgtcac ctagaattgg
       61 ctattaacgc tttattacaa gctgaattaa cggtatttct tgactatgaa aagtatgata
      121 gagctggatt taattcaggt aattcccgta atgggaatta ttcgcgctct tttaaaacag
      181 agtacggtga attgaattta gtaataccta gagataggaa tggagacttt tctcaacaaa
      241 ctttacctgc ttataaaaga accaatgact ctttagaaac cactattatt cagctagttc
      301 aaaaaggaat tactatgtcc gaaatctctg atctaatcga aaaaatgtat ggtcattatt
      361 acaaaccaca aactatttca aatatgagta aaattgtgtc tgaagatgtt tcggcattta
      421 aagaaagaac tttagaagct aaatactcag tcatttttat ggatgctact catattccct
      481 taaaaagaca aaccgtatca aaagaagctg tctatatagt aattggtatc aggttggatg
      541 gaactaaaga ggttctagga tttactatag ctccaactga atctgcttat gtttggaaag
      601 agattcttca agatctaaaa gaccgtggtt tagaagaggt tttgttagtc gtaacagatg
      661 gtttaagtgg tattgacgat agtattcata gtgtttatcc aaatgctcaa tttcaacaat
      721 gttgtgtcca tatatctaga aatatcgctc ataaggttcg tgttagtgat cgacaagaaa
      781 tctgtagcga tttcaaatta gtttaccaag caagttcaaa agaagaagca aataatcaaa
      841 taaggtttat gatagataaa tggaaaaagc agtatccacg agtggttaaa ttgctcatga
      901 atcctgctat attaaccttt tataatttcc ctccgtcaat cagaagaact atttattcaa
      961 ctaatttgat tgaaggtttt aacaaacaat taaagaaata taccaaaaga aaagagcaat
     1021 ttcctaatga agaatctctg gagagatttc tagtatctca attcaacaac tataatcaaa
     1081 agtttctatg ccgagttcat aaaggtttta aagaaataca tgatacatta gaatcaatgt
     1141 tttaacttga tcaacagaat gggcttttcc atttacacat aattattgac acaacctatt
     1201 ctggaaactt acaaataaaa gcttattctt cagccacctt cgggtggtta ttttttataa
     1261 aaaaatgtaa aaaaatattg atacataaat aaattagttg tagtaaatag ttttagaatt
     1321 gaatttctct atccttttta aataattttt tagacaaaaa acagaaagtg tctaaagaaa
     1381 gcttgacgaa gaaaataatt tttaataact tatttaagga aattttttga aggagaagat
     1441 aaaagtgaga aaaaagatta ttattaatgc tggagtaatt ataggattga tgttagtaat
     1501 tttctccgga aagcaatatg ctgataatat tttattatgg ggaggggaag ataatattga
     1561 aaagatcaac aacaatttaa ctatattaga cacagctcta gaaaataaag agcaaaaaat
     1621 tagtatttta aattcacaat tgtcttcaaa caaccaaact cttgaacaac taagaactaa
     1681 tattgaagtt tccaaacaaa aagtggcatc tttagaaaac gacaagaatc aattagtatc
     1741 agagaaaact aatttagaaa atcaattgtc agcaaaagac tctgaattgc aaggaaaaca
     1801 aaatgaaatt aatgcgaaaa tagacgaaat taaccaaaaa gtagctgaaa taaatcgatt
     1861 aaatagcgat tggaataatc gtttacaaaa tgaaaagaac aaatttaatg aagaacaatc
     1921 tactattaat agtttaaacc agcaaattaa tcaaatgttg agtgaaaaaa ataacattca
     1981 aaatcaactg caagctactc agcaaaagct agaagaagaa aagtcaaaaa atagtagttt
     2041 gaataattac attgaaaagc ttcaaaaagc taaaaatgat gtagaggata ccgcaaataa
     2101 agcacaacaa attgtaaatg aacatacaat ccaatagata tagttttaat ttaacaaatg
     2161 gtatgtttgg agataatgag atagaatata aatgtcataa tattatacaa tctaaacacc
     2221 gtttcctttt ctatttttga tgacatcagt atatagctac tcgaaagagt agtcttttta
     2281 ttattctcgc ttattattga tatgaaaatt tcgatttgac aaaaggtacc gaataatttt
     2341 gtaatatgaa ttattatcaa gaagtaatta tgatgataac atatggaaac tagttagtaa
     2401 taataacagg tgattaaact tttgaacgac ttgtaattct atattttttc ttttaagtaa
     2461 aaaatatagg tgattttttt tgacttcata tttataataa agacacgtaa atcaattatt
     2521 tttcatttta ctttaactaa taatgtttat ttggagggat tattatgtta gatgatagat
     2581 tgacgtgttc taattgtggt acattatttt actatgagga agttagaaat attgtaaaac
     2641 atagaaaaaa agaaatgcct atacgttgtc caaattgcaa tgaagttatt aagcgaaagt
     2701 tgtctcatgg ttattttgtc agctacgaac tatatgaaga aagtaaaata aatctgaaaa
     2761 aaaaaccaaa atactataaa aatttgaaaa ctggagctat tataactgaa aaagaattta
     2821 aaaatttagt gactgaagaa gaaagcaggt tttataattt gtctggtaat atttgccctg
     2881 gatttatgga tcagattatt gaaaatgagt caattgaatc aattgaaaac tatgttcctg
     2941 ttgacttacc aaaatagaaa aaataatcct gtttttacag tgaattattt taattttgat
     3001 tttcaataaa aatatattac aataataatc gtaatagcta atgaaacaat ttctcaatct
     3061 ttttaccact ccaaacaggg agcgtcaata attttgtgta aataactcgt ccttctgcaa
     3121 aataatgggt tactcagtaa acattgaagc taatgtatcc gtcacttgtt ggaagccttt
     3181 atggcttcta tttaagaatt tttgattgta tgtatcaaag atggatacta ggaaacgctc
     3241 tagtgattct tcattttgaa actgctcttt tctgcggctg tatttcttga tttgtttatt
     3301 gaaagattcg attgtagaac cagaaggaat ggagaacact tttgaacttt acaacaaaac
     3361 tactgttgat aaattaattc caattttagt tccaactgat ttaaatggtc atgatgtttt
     3421 acttcgtttt aacggatttt taggtgagga ttatagatac ctaaaaattt ctgatcctca
     3481 acctttaaca gaa
//
LOCUS       DAFELK010000123         3398 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFELK010000123
VERSION     DAFELK010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.132"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..276
                     /locus_tag="LP433_002878"
     CDS             <1..276
                     /locus_tag="LP433_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HBL2006975.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            419..640
                     /locus_tag="LP433_002879"
     CDS             419..640
                     /locus_tag="LP433_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006976.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            656..1498
                     /locus_tag="LP433_002880"
     CDS             656..1498
                     /locus_tag="LP433_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006977.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1561..3363
                     /locus_tag="LP433_002881"
     CDS             1561..3363
                     /locus_tag="LP433_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HBL2006978.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
BASE COUNT         1229 a          469 c          702 g          998 t
ORIGIN      
        1 gaactcatca agctggctaa taagggtcaa gattatgaac atctagcaga tgagattgat
       61 gagctgagag acaagcgaca gctcctttta gtagaagatg cctccctcag tggcgagaac
      121 gagcgaatca atgagctgat tgaatttatc cgcaagaaca aattccgtac cttagagtac
      181 gatgataagc ttgtaaggaa gataatccag agcgttacag tctatgaaga acacttcgtc
      241 atatccttca aatctggcat cgaaatggaa atatgaaaac cagaagtaaa tagcccatga
      301 ttctacagta gagtcgtggg ttttcttttg cttgctgatt ataataatat tttaataact
      361 attgttatta taaaccaaat gatttataat attcttagcg taaacttgga ggtgctgtat
      421 gactacggca gaaatgatta aagaactgtg tgagcaaatg aatataagtg tttccgaact
      481 tgctagacgt attggacaga ctccacagaa tttcaataag aaattacaac gagaaacggt
      541 aaccttagat gagttgaaag cgattgctga tgtgctaggt gtcaagtttg tgcaggcttt
      601 tatattgcct gatggcaatg aaataaagat aggtaattag gaggtgtaat ttgtattgaa
      661 aatcataaca ataaatgatg ttgagtatgc tgtatttgct gctaatgaag gtacttccaa
      721 accacaacct catatcatag aaacgaaatc tggtactatt ccagaaggaa aacaactgag
      781 tttattaaaa gaatatctta agcagaatga tatttcccca ataaaaggag caacaacata
      841 ttggtgcatt gacaaggttc ttaagcttga ttcaagtaaa gaaaaaacta taagtgaaac
      901 aatccataaa caaaaatact tatctttaac tgaagaaaat attgagaaac agcataagtt
      961 tgtaggtgca agctctaatt atgggaaaga aggtctaata atacatgatg ttttgaatgc
     1021 atttcctctt cataatgatt taaatactat tgcgatgaag attgcggtaa ttgatgtaac
     1081 aaattcaaca catctttctc aatataagag caggttgtct ctatatgatt tggctaaagt
     1141 aattctggag attccaaatt ttgatgatcg gttggcaaaa ggagatcctc agttgataaa
     1201 tattatcgca aggaacattg gtgcagttaa tatgttctca tttgcatcca agtactgtac
     1261 atatcataat gtggaagtgt gtgggagaga tgattactcc atctttgatg gtatcgttaa
     1321 aaatactctt ccacactata tccaaggact aactacgaat aagattgata cgtggcgaag
     1381 aagttttgat tacgaggcat ttaacgaatg tgttggaaaa ctacttgatg aaaataatat
     1441 acatattcct tttagaagaa gaaagttaga tcacttcttg tggtatgcga ataggtagaa
     1501 tataagaaaa aggcatcgta aaagtgattc tggataaaat taatggggga ggaaataata
     1561 gtgggattat ttgattttct aaagaaaaaa caaggaaagg ttagtaaaca cgttgattat
     1621 caactggctt ctagtctatt tcgtactggt aaagtttttg ctgaaaaatt ggaagtggac
     1681 atatcaaatg tagatgagtt tcgtaaaact tttatcgctt ttgatgtgga aacaactggc
     1741 ctaaattctt cttcagatag aattgtagag attggtgcgg tgctatttaa agaaggagtt
     1801 ccaattcaat cattcggaac tcttgtcaat ccaaaagtta gaattgcagc ctcagcttcg
     1861 gcaataaata atataactaa tgaaatgcta aactctgctc caaatgagca ggaagtttac
     1921 ccccagttgg tagaattttt aggagatgca ctagatggaa aaatcactat gtgtgcacac
     1981 aatgcaagtt tcgattttgg atttttaagt aacacatttt ctagacttgg gtatgatgct
     2041 aaaattaagt atgttgatac tctgagtctc tctagaaaac atataaaagg cattgtaaat
     2101 cataagcaag agactgtagc ggaatatttc ggattaataa atgacactgc ccatagagcg
     2161 gaatcagatg cagatatatg cggaaagatt ttttggggtg ttttagatat tattgaggag
     2221 tcgttggaag aacaaaaaaa gcaaatagaa aagatgactc cagacataaa agaacttgaa
     2281 gcttgtgctt ttattcaaga tattattgag aaaaaaggat gcgacaccag ttggatcagg
     2341 tatcgaaaaa acagtaataa ttatgtcgat gtaacttgtc tatatacatt cttaaagttt
     2401 aagtttgcta agaagggaaa ttacatcatt attagaaaag atgctacaaa tggaattgat
     2461 ttacctatag aaccttgtac tgtaagtgaa ggcggtacaa caaatgtgcg agtctatttt
     2521 cgtagcccct ttgacttaac gcctctttca aattatattt tcagtgctta tagcgattgt
     2581 tataattcta tgaatgaata tatgagtgtt agtaattaca ctaaaaaaga agcagagcaa
     2641 agccttagta tgctgaaatc tatttcaaaa tcagcgatga aagagttatt attcgatgca
     2701 aaaaatcgtg gatatgatga gactgaagtt aacctaaata ttgaaaaagt gatatctaga
     2761 gaagatgtaa ttattaacgg gttgcataat cgagtttcat taaacaagat acgaaatata
     2821 gggaattggg agaaaggatt tgatgcaggt tatccatatt gggaacgtgg agaaactgct
     2881 aggaaaaatg gcaaagtaga tgaagctatt gcactttttg ataaagctcg atataacggc
     2941 tatgatgctc ctgcgctata tgattcttat gctaaagctt atcgaaaaat taaggattac
     3001 gataatgaaa ttctcattct tgatgaagga attatgcgta aaacacggca cgatgttggt
     3061 actttagagg ctcgtaggga taaggcaatt aagctattat ttgctaaaca agaggcagag
     3121 cggatagcta aggaaaaatc tgattttcta aaagcgaaca aaaaagagga tgcgattagt
     3181 gagcctagca agaagcgtgg aagacagatt attcaaatga ctgatgatgg aacaataata
     3241 aaagaattcg atactatagc ttctgctgta aaagaagttg gcgttaactc aaaaagtatt
     3301 agggatgctg caaatggagt tcaaaaacat gctggaggat actactggaa atacaaagat
     3361 tagcagataa tctaagataa cctaggatct tcttaata
//
LOCUS       DAFELK010000124         3396 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFELK010000124
VERSION     DAFELK010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.133"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            647..964
                     /locus_tag="LP433_002882"
     CDS             647..964
                     /locus_tag="LP433_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL2006979.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="LP433_002883"
     CDS             complement(1055..1420)
                     /locus_tag="LP433_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006980.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="LP433_002884"
     CDS             1628..2110
                     /locus_tag="LP433_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006981.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="LP433_002885"
     CDS             2307..3197
                     /locus_tag="LP433_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBL2006982.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1172 a          519 c          619 g         1086 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac tttttt
//
LOCUS       DAFELK010000125         3280 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFELK010000125
VERSION     DAFELK010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.134"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(552..2165)
                     /locus_tag="LP433_002886"
     CDS             complement(552..2165)
                     /locus_tag="LP433_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2006983.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="LP433_002887"
     CDS             complement(2306..3214)
                     /locus_tag="LP433_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2006984.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1063 a          560 c          574 g         1083 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atttatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa
//
LOCUS       DAFELK010000126         3240 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFELK010000126
VERSION     DAFELK010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3240
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.135"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(452..793)
                     /locus_tag="LP433_002888"
     CDS             complement(452..793)
                     /locus_tag="LP433_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2006985.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NRFIEKLQRKV"
     gene            complement(783..1064)
                     /locus_tag="LP433_002889"
     CDS             complement(783..1064)
                     /locus_tag="LP433_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBL2006986.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFDEA"
     gene            complement(1435..1674)
                     /locus_tag="LP433_002890"
     CDS             complement(1435..1674)
                     /locus_tag="LP433_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006987.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEDLLRKTQRKGYPDKILKQIGYYM
                     PEERIEKEFCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            complement(1694..1942)
                     /locus_tag="LP433_002891"
     CDS             complement(1694..1942)
                     /locus_tag="LP433_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006988.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            complement(1957..2523)
                     /locus_tag="LP433_002892"
     CDS             complement(1957..2523)
                     /locus_tag="LP433_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006989.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            complement(2524..3069)
                     /locus_tag="LP433_002893"
     CDS             complement(2524..3069)
                     /locus_tag="LP433_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2006990.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            complement(3095..>3240)
                     /locus_tag="LP433_002894"
     CDS             complement(3095..>3240)
                     /locus_tag="LP433_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL2006991.1"
                     /translation="VFPSENDKSFTTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQEN
                     GSL"
BASE COUNT          926 a          706 c          365 g         1243 t
ORIGIN      
        1 gttggttgag ttgtggctcc tattcaaaat tcactaatct gttatttttt atttctattc
       61 aaataggtaa cgttcgtttg caagcaaact ctctctatgt aacttgccag ttacatcagc
      121 ggtaacgcta cgtcgcaagc gacttgctct aatgaaactg ccgtttcatt ctgcctgttc
      181 gttcgtagca agctacttca ctcaccgtat ccgtctgaat tattgttatt tattgctatt
      241 caatatccgt cagacatttt atttatttac atacatttta tataaaatat atattataat
      301 tcgtatatta ctaaatatca ttatttaaca attcttaacg ttttattaat gtttataacc
      361 acgtatatat ttacgtatat tttcatatac ataaatacgt ttatataaac gtatatctta
      421 atatacatat aaacaaaaaa gaaaagcctt gttagacttt tctttgtaat ttctcgataa
      481 acctatttag ctttttcgta tcactagctg ataacatacc aacctttttg aatgatatgt
      541 tctctcggct tttgggaata gcctttaaag accctacgtc aatccatgat tgctttttaa
      601 gtcctgcttt ttcccattct gcaataggaa aatacaccct ctttatttgg tctgattttt
      661 tctcatattg acttgtgatt ccaaagaatt ctactctatc ttctttatca ctaaccacca
      721 aaataggtct tcttttacca ccatttttat ctgtaaatgc aacatatacc gttactatct
      781 cattaggctt catcgaacca ctcttctaac ttttcatctg tatctagaac atctactggc
      841 atgtccttag ttagctgttg caatctgatt ccttgcttct cctcttcact tagctttatc
      901 tctactggaa actcacctct agcgactact tgtttgtaaa gaattgttat tgctgttgta
      961 ggatttaaac ctagctcttc caatatcatt tctgcgttct cttttaaatt cttgtctatt
     1021 ccgacttgga ttctgctttt ttcagttgga tttttgacct tcatttcatc cactcctttt
     1081 gagtataaaa cactcattat ttatcaaatt gtccacattt atgattatat tatactctta
     1141 ataaactaca ttgcaagtaa tctaatcaaa ttaagatgct atatcatacg gtaattgaac
     1201 aaattgtcgc taacccacac atacggaatc gtaatgaatg aaaaaaagac aagcctattc
     1261 gcagtaggct tgtctttgtg cttctcttgt acaaaatctt cacatttgta aattaatttt
     1321 agcacctttg ttaggaaaga acaacttaaa tgagatgcta aagaattaat agttctcaat
     1381 ctagcatatt cacttaatac catcttatct tcattcatgg ttcaccacct catcttaatt
     1441 attttcaaat tggcaaatca atttattttg ggttaacaaa actaatagct gttcactatc
     1501 aaaaagaacc tcacaaaatt ctttttctat cctctcttct ggcatgtaat aacctatttg
     1561 tttcaatatc ttatctggat aaccttttcg ttgggttttt ctcaataaat cttcatcatt
     1621 tccaacataa taataagaac accattgcat acccttactt ttaaattttg tcatgtttct
     1681 atcttccttt cacttattga cccaaccatg aaaaaatata ttttgctaaa tcttcctttt
     1741 ctattccata taaaacattc tctaaatcca atttatattc ctcgtcaaca aggctttctg
     1801 tatcgtcatc ataaagaaca tatactgcat aatttctttc gtaaaaggca ttagcaagac
     1861 ttctgctaat acctaccatt cctttccatg tataaccaaa atcaaccaaa tcttcatgat
     1921 ctagaaaatc cattccttcc atgctgattc acactcctat tctgctgttg tgtaatatgc
     1981 aacgcaatca tctgccccta ctaaccacac acaccaatct tcaatttcat catcgcttct
     2041 cttactcaat tcctctttgg tacaaaaaac tacttcacca ttttcttttt ccatctcata
     2101 atcttgtagc atgtattcaa accaacttct ttcggttgga aattctatct cgtggcaact
     2161 ctggcaaata aaatcaccat attcattgat tcggtagcaa ccttcatctt ctacaaattc
     2221 atgattacaa caaacacatc tagtacctgt taggacttcc ccattaatcg ttgttctaac
     2281 ggtatcttcc cttgctacgt gttcactgct gacaagccaa tcaatgattt tctttgccaa
     2341 ttcttcatca gaatcggcaa agcctttaaa cgtgtttctc tttccttgaa agtagtattt
     2401 gcaacttgcg gtagtttcta tggttccata acttttttgg aataattcaa tcatttcacc
     2461 atcaatcact ttttgacttt tcgcttctaa attagggaac tggtcttttc ttttttcaaa
     2521 cacttatttc acgctctctt cttctaggtt tattccataa ttttctagca ataatctgta
     2581 tcccttaata aaatctttcg tagcaaactc ttttccgctt tcacaaaact tgtttagtcc
     2641 tatctgttga ccctcaaaat caaacaatcg caatctggtt ttatcatcta gactaaatcc
     2701 attttcatcg aacaccatct ctaaatgagc atagccatca ttgttatctg aaaacttcat
     2761 cacatcttca atcgtttctt gataaggttc atagcgccca ccaaaccctg tttcatcata
     2821 agcactcact ccagattcat aggtaacaaa attgataact cctgtacttc tatcaaagat
     2881 tccttttgct aattcttctc ttgatttatc tcgtaagtcg tatgctttat tgattaaata
     2941 aattccttga ttcaatacgt ccatcagcat atatcgacca tacccccact gataatgaat
     3001 cgacacgctt gctttcgttt tgctgttacc atatttgact gtaattaacg cttgtgttct
     3061 ttcgcccatc ttgttttcct cttttctcta atttttataa agaaccattt tcttgaaatg
     3121 agtaatagct tgtgttttta cttgttacga tgatatggtc taacaattca ataccaattg
     3181 tttttcctgc gtttttcaaa ttcgtagtaa aacttttgtc attttcactt ggaaaaacat
//
LOCUS       DAFELK010000127         2990 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFELK010000127
VERSION     DAFELK010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2990
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.136"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..149
                     /locus_tag="LP433_002895"
     CDS             <1..149
                     /locus_tag="LP433_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2006992.1"
                     /translation="RRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVS
                     MFTE"
     gene            204..860
                     /locus_tag="LP433_002896"
                     /pseudo
     CDS             204..860
                     /locus_tag="LP433_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(857..1480)
                     /locus_tag="LP433_002897"
     CDS             complement(857..1480)
                     /locus_tag="LP433_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006993.1"
                     /translation="MKIAYIRVSSIDQNEQRQIEEMKKFGAEKIFIEKQSGATITHRP
                     IFQEALEFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PHLDKFIKDLIIQILAMIAEQERTESKRRQAQVIKIAKANGVYKGRPKLYSADTKNPQ
                     RRLVYENIVKDLNEGIAISKIAKNYNITRQTIYRIKNDIEYNSNQMN"
     gene            1798..2136
                     /locus_tag="LP433_002898"
     CDS             1798..2136
                     /locus_tag="LP433_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2006994.1"
                     /translation="MNGIEDENLRRLINSLVIELYKYQAESERKKIKERQAQGIEIAK
                     KKGKFKGRQLKFKKNDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVD
                     QRKNNEKRDS"
     gene            2228..2933
                     /locus_tag="LP433_002899"
                     /pseudo
     CDS             2228..2933
                     /locus_tag="LP433_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320596.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
BASE COUNT         1081 a          464 c          514 g          931 t
ORIGIN      
        1 gccgtagaaa agagcagttt caaaatgaag aatcactaga acgctttcta gtcagcattt
       61 ttgatacata caatcaaaaa tttctaaaca gaagccataa aggttttcaa caggtaaccg
      121 atacattagt ttcaatgttt actgagtaac taattatttt gcaggaggac aatttattta
      181 cacaaaatta ttgacgctcc ccacaatttt tagaagaatt atctggagaa gaatatagat
      241 tattcctaaa taataatatt ttaaaattaa tatcttatgc caagaaagct aatagcctat
      301 ctttagtaga taacttagat aatcttttac ccgataaact tatttatgat gagaatgaag
      361 ataattcaca aaaacaaata attatatttg aattgtattt aaagtggctt agcagcctgt
      421 cagtgtcacc agaaagcaat gatgatgata aatattttgc gaacaaactg tttcaattta
      481 tatttccaga ctattcttca atgccatttt ttacattaat aaattttatg ctgtatgtta
      541 aagaacactt aggatatgat gatttagtag aaatgataaa ggcatatgat aaagaacctt
      601 atccattcaa aggaatcaat actggttcag atatggctat gatttcaggc gaaactgtag
      661 aagaaattct agctaattac aaagaacaaa atataaaaac tctggaatta attaaaaaga
      721 atataaaata ctatgatcct ttactagcga ataaagaaaa tattgataag ttattaaatg
      781 caattgctga ttctgatgtt agatctccta gaattgatga gttaaaagaa gaaattttaa
      841 tgtataaaga acttttttaa ttcatttgat tactgttata ctcaatatca ttcttaattc
      901 tgtaaatagt ttgtctagta atattgtagt ttttagcaat ttttgaaata gctatgccct
      961 catttaaatc cttaacgatg ttttcataaa ctaaacgtcg ttgaggattt tttgtatctg
     1021 cactatagag ttttggacga cctttataga cgccatttgc ttttgcaatt ttaatgactt
     1081 gcgcctggcg tcgtttagat tcggtacgct cttgctctgc aatcatggcc aaaatttgga
     1141 tgattaaatc tttaatgaat ttatccaaat gaggattgcc aattgcttca gccatgatcg
     1201 gtagactggt gatgatcagc tgcacgtttt tcttctttag gtaattgact gaagcaatga
     1261 tttcgtcgta atttcttcca agtcggtcga ttgcttcgac aataaaaata tcttggtctc
     1321 ggacaaactc taaagcttcc tggaaaatcg gtcgatgagt aatcgttgct ccagattgtt
     1381 tctcgatgaa aattttttct gcgccgaact ttttcatttc ttcaatttgg cgttgctcat
     1441 tttgatcaat cgacgaaact cgaatataag caattttcaa aatttttacc tacttcctca
     1501 aactatttaa aatacactca aaatcaacac taattttttt atacactata aagctgtcat
     1561 ttttctagat aaatggcata aattttcagc gctaagtgac aaaagcaact aatttttcat
     1621 gatagatttt taaatatctc aatctatctc caaaattagt tgcttttgta gctatagttg
     1681 actatgaata tgacaaataa ttagaaaaaa ctgtgccaat taaatatcaa aatgacaaat
     1741 tgatgaatca aattcaaatt aaggggggca accctggaag tcttaaattt accctcaatg
     1801 aatggtattg aagatgaaaa tttaaggcgt ttgattaata gccttgtcat tgaattgtac
     1861 aagtatcaag cagaatcaga acgaaaaaaa attaaggaac gtcaggcaca aggaatcgaa
     1921 attgctaaga aaaaaggcaa attcaaaggt cggcaactga aatttaaaaa aaatgatcca
     1981 cgtttaaagc atgctttcga tttgtttttg aatggtttat ccgataaaga agttgaagaa
     2041 caaactggga tcaatcgccg aacgtttaga aggtatcgag caagatataa cgtgacagta
     2101 gatcaaagaa aaaacaatga aaagagggat agttaatgag tacggttatt ttagctgaaa
     2161 aacaagccag gcattagcct acgcaagtgc tttaaaacaa agcaccaaaa aagacggtta
     2221 ttttgagatc aaagacccac tatttacaga tgaaacgttt atcacctttg attttgggca
     2281 tttagtggaa ttagcagaac caggtcatta tgacgaaaag tggcaaaatt ggaaacttga
     2341 atctttgccg atttttcctg atcgatacga ttttgaagtt gcaaaagata agggaaagca
     2401 gtttaaaatt gttgcagaac ttctcaaaaa ggcaaataca attattgttg caacagatag
     2461 cgacagagaa ggtgaaaata tcgcctggtc gattatccat aaagcaaatg ccttttcaaa
     2521 agataaaaca tttaaaagac tatggatcaa tagcttagaa aaagatgtga tccgaagcgg
     2581 ttttcaaaat ttgcaaccag gaatgaatta ctatcccttt tatcaagaag cgcaaacacg
     2641 ccaaattgcc gattggttga tcggcatgaa cgcaagccct ttgtatacgt taaatttaca
     2701 acagaagggc gtacaaggta cattttcact aggacgtgtt caaacgccca ccttatacct
     2761 tatttttcag cgccaggaag ctagtataaa agtaaaacaa gggtcattta agggcgttct
     2821 aagccccaca cagcgtttta aaacccaaga ggagcttttt tgcttttgtt tcttctaaac
     2881 aagctaaaat aggcaatcaa gaggggataa ttgctgatgt tcaaaccaaa gagatggata
     2941 ggctacaatt aactagacag aaaaattaag gtgtgtagac tagaagaaaa
//
LOCUS       DAFELK010000128         2894 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFELK010000128
VERSION     DAFELK010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.138"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            256..1224
                     /locus_tag="LP433_002900"
     CDS             256..1224
                     /locus_tag="LP433_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL2006995.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1217..2248
                     /gene="vanA"
                     /locus_tag="LP433_002901"
     CDS             1217..2248
                     /gene="vanA"
                     /locus_tag="LP433_002901"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL2006996.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2254..2862
                     /locus_tag="LP433_002902"
     CDS             2254..2862
                     /locus_tag="LP433_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL2006997.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          856 a          555 c          706 g          777 t
ORIGIN      
        1 ttccagcgat gccagacttg gttgataaaa ggaggtccta agagatgtat ataatttttt
       61 aggaaaatct caaggttatc tttacttttt cttaggaaat taacaattta atattaagaa
      121 acggctcgtt cttacacggt agacttaata ccgtaagaac gagccgtttt cgttcttcag
      181 agaaagattt gacaagatta ccattggcat ccccgtttta tttggtgcct ttcacagaaa
      241 gggttggtct taattatgaa taacatcggc attactgttt atggatgtga gcaggatgag
      301 gcagatgcat tccatgctct ttcgcctcgc tttggcgtta tggcaacgat aattaacgcc
      361 aacgtgtcgg aatccaacgc caaatccgcg cctttcaatc aatgtatcag tgtgggacat
      421 aaatcagaga tttccgcctc tattcttctt gcgctgaaga gagccggtgt gaaatatatt
      481 tctacccgaa gcatcggctg caatcatata gatacaactg ctgctaagag aatgggcatc
      541 actgtcgaca atgtggcgta ctcgccggat agcgttgccg attatactat gatgctaatt
      601 cttatggcag tacgcaacgt aaaatcgatt gtgcgctctg tggaaaaaca tgatttcagg
      661 ttggacagcg accgtggcaa ggtactcagc gacatgacag ttggtgtggt gggaacgggc
      721 cagataggca aagcggttat tgagcggctg cgaggatttg gatgtaaagt gttggcttat
      781 agtcgcagcc gaagtataga ggtaaactat gtaccgtttg atgagttgct gcaaaatagc
      841 gatatcgtta cgcttcatgt gccgctcaat acggatacgc actatattat cagccacgaa
      901 caaatacaga gaatgaagca aggagcattt cttatcaata ctgggcgcgg tccacttgta
      961 gatacctatg agttggttaa agcattagaa aacgggaaac tgggcggtgc cgcattggat
     1021 gtattggaag gagaggaaga gtttttctac tctgattgca cccaaaaacc aattgataat
     1081 caatttttac ttaaacttca aagaatgcct aacgtgataa tcacaccgca tacggcctat
     1141 tataccgagc aagcgttgcg tgataccgtt gaaaaaacca ttaaaaactg tttggatttt
     1201 gaaaggagac aggagcatga atagaataaa agttgcaata ctgtttgggg gttgctcaga
     1261 ggagcatgac gtatcggtaa aatctgcaat agagatagcc gctaacatta ataaagaaaa
     1321 atacgagccg ttatacattg gaattacgaa atctggtgta tggaaaatgt gcgaaaaacc
     1381 ttgcgcggaa tgggaaaacg acaattgcta ttcagctgta ctctcgccgg ataaaaaaat
     1441 gcacggatta cttgttaaaa agaaccatga atatgaaatc aaccatgttg atgtagcatt
     1501 ttcagctttg catggcaagt caggtgaaga tggatccata caaggtctgt ttgaattgtc
     1561 cggtatccct tttgtaggct gcgatattca aagctcagca atttgtatgg acaaatcgtt
     1621 gacatacatc gttgcgaaaa atgctgggat agctactccc gccttttggg ttattaataa
     1681 agatgatagg ccggtggcag ctacgtttac ctatcctgtt tttgttaagc cggcgcgttc
     1741 aggctcatcc ttcggtgtga aaaaagtcaa tagcgcggac gaattggact acgcaattga
     1801 atcggcaaga caatatgaca gcaaaatctt aattgagcag gctgtttcgg gctgtgaggt
     1861 cggttgtgcg gtattgggaa acagtgccgc gttagttgtt ggcgaggtgg accaaatcag
     1921 gctgcagtac ggaatctttc gtattcatca ggaagtcgag ccggaaaaag gctctgaaaa
     1981 cgcagttata accgttcccg cagacctttc agcagaggag cgaggacgga tacaggaaac
     2041 ggcaaaaaaa atatataaag cgctcggctg tagaggtcta gcccgtgtgg atatgttttt
     2101 acaagataac ggccgcattg tactgaacga agtcaatact ctgcccggtt tcacgtcata
     2161 cagtcgttat ccccgtatga tggccgctgc aggtattgca cttcccgaac tgattgaccg
     2221 cttgatcgta ttagcgttaa aggggtgata agcatggaaa taggatttac ttttttagat
     2281 gaaatagtac acggtgttcg ttgggacgct aaatatgcca cttgggataa tttcaccgga
     2341 aaaccggttg acggttatga agtaaatcgc attgtaggga catacgagtt ggctgaatcg
     2401 cttttgaagg caaaagaact ggctgctacc caagggtacg gattgcttct atgggacggt
     2461 taccgtccta agcgtgctgt aaactgtttt atgcaatggg ctgcacagcc ggaaaataac
     2521 ctgacaaagg aaagttatta tcccaatatt gaccgaactg agatgatttc aaaaggatac
     2581 gtggcttcaa aatcaagcca tagccgcggc agtgccattg atcttacgct ttatcgatta
     2641 gacacgggtg agcttgtacc aatggggagc cgatttgatt ttatggatga acgctctcat
     2701 catgcggcaa atggaatatc atgcaatgaa gcgcaaaatc gcagacgttt gcgctccatc
     2761 atggaaaaca gtgggtttga agcatatagc ctcgaatggt ggcactatgt attaagagac
     2821 gaaccatacc ccaatagcta ttttgatttc cccgttaaat aaacttttaa ccgttgcacg
     2881 gacaaactat ataa
//
LOCUS       DAFELK010000129         2791 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFELK010000129
VERSION     DAFELK010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.139"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..1350
                     /locus_tag="LP433_002903"
     CDS             <1..1350
                     /locus_tag="LP433_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2006998.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..>2791
                     /locus_tag="LP433_002904"
     CDS             1484..>2791
                     /locus_tag="LP433_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2006999.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFI"
BASE COUNT         1092 a          383 c          542 g          774 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat t
//
LOCUS       DAFELK010000130         2744 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFELK010000130
VERSION     DAFELK010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.140"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            198..1163
                     /locus_tag="LP433_002905"
     CDS             198..1163
                     /locus_tag="LP433_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL2007000.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMQLNEGNGFVKSVGKNGWQIVDQYEENIAYIELLQF
                     HEGKARIDFNPNKIGQFLASSMKNFIHDLFLEPHFSRADIACDMVNVPDEFIMQYRVV
                     DPVSFKPIYGRSGKLESAYWGSRASERQIRLYNKKLEQETKRKVVPKEVETWWRLEMQ
                     LRRGKATDWHNMVQESLNSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLKQELDTWLLGLDVTEK"
     gene            complement(1561..2241)
                     /locus_tag="LP433_002906"
     CDS             complement(1561..2241)
                     /locus_tag="LP433_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL2007001.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGVTA"
BASE COUNT          855 a          463 c          580 g          846 t
ORIGIN      
        1 aaaaaaatag tcgagcagtg ttgacgcact ctcgaccttt acggaaacta cttcacctag
       61 ttccgtaact caagttcatt atacgaatat ttttaggttt cttcaagcta gagatttttg
      121 gatgtggatt tttagagtta cgtgaactct ggaaattctt tccaagaatc tcttttttcg
      181 ttgaggagga gctatttttg agtaaaaaag gcataatcgt aaatgagtgg gaaaaactta
      241 accgtatttc taacaggcgg ttaaatgttc aaaatttgaa caccccccta aaattacagt
      301 ggtcaatcga ccgaattacc attgttggaa aattgaaaga aaatatttat tatcacacac
      361 caaatgatgt cttgatttta aattttgagc aattgatgca attgaatgag gggaatgggt
      421 ttgtcaaatc agttggtaaa aatggctggc aaattgtcga ccaatacgaa gaaaatatcg
      481 cgtatattga gctcttgcaa tttcatgaag ggaaagcacg aattgatttt aatcccaata
      541 aaattggtca gtttttagcc agttcgatga aaaatttcat tcatgatttg tttttagaac
      601 cccatttttc gcgggcagat atcgcttgcg atatggttaa tgttccggat gagtttatta
      661 tgcaatatcg tgtggttgac ccggtatcgt tcaaaccgat ttacgggcgt tctggaaaac
      721 tagaatcagc ttattggggt agccgtgcca gcgaacgaca aattcggcta tacaataaaa
      781 aattggaaca agaaaccaaa cgaaaagttg taccaaagga agttgagact tggtggcggt
      841 tagaaatgca actacggcgt ggcaaggcaa ccgattggca taatatggtt caagaaagtt
      901 tgaatagttt tgcgagcctg cattttttgc cgattgatac aacacctaca gatagaataa
      961 tgctcgctgg tttaatgtct gatcaaaatt tctggtctct tttgtcgagg aattcaaaat
     1021 ataaatatcg ggaattgctg aaagaagaaa gtcaaaatga tgaattgacg aatcatttgc
     1081 gagaaacgtt tgcagaatcg gcagacaatt tgaaacaaga attagacacg tggcttttgg
     1141 gtttggacgt gacagagaag tgataccgaa taagaaaagt cagatgagtg agagtaaatt
     1201 tacgtcaatg tttaatgacg tgagtttacg ataagcgatt attttgcgtg aagcaaaata
     1261 aagcgtaaaa ggagttgaga gcgtgacacg ctttcggctc cttttttcgt tgtcacttgt
     1321 gacagcgaat accctcggag agcatttgga attgtgacag ccatgtcaca attaggaaaa
     1381 tgttactctt tgtcaaagag taacagaaag gtttacactc tttttattag cgacagcgcg
     1441 aaggaggggt ttaacttggg gtttagtatt tcgttcaaaa agggaacaaa aaatacaagc
     1501 atttctggtt ctgttgcgaa gtttgaaaat caaacgcgcc ctctctgaac tccaaatatc
     1561 ttaggctgtt actcccatta ataccttgat ttcagtagac accgaaaagc cgaagagcgt
     1621 tccatttctt cggttctttt tatatattcc tcgaatggtc tccatgccct taatcgtgga
     1681 agaggctgta cggagacttt gataaaattt atttcgtcgt ttaataggtc gatggtcttg
     1741 ttctattaaa ttgttaagat acttcacagt tcggtgctct gtcttagtat ataaacccac
     1801 actctgtaac tttctaaagg cggagccaag agaaggtgct ttatcggtca caattgcttt
     1861 cggctcacca aactgtttat ggagtcgttt taagaaagca taggctgctt gcgtatcccg
     1921 tttctttcgt aaccagatat ctaaggttaa gccgtccgca tcaattgcac gataaagata
     1981 atgccaacgt cccttaattt tgatataggt ttcgtccatt ttccatgaat agaaggattg
     2041 tctatttttc ttcttccaaa gataatagag gactttgctg tactcttgta cccaacgata
     2101 aatcgtagta tgacaaacat ttattccacg atcatataac aattcctgaa cttcacgata
     2161 gcttagattg taacgcaggt agtaaccaac agcgacaata atgacgtctt ttttgaattg
     2221 tttgccttta aaatgattca ttactctgtc ctctctgtct tttttctcaa ttttacacta
     2281 aaatagattt tttggaaaac tttgcaacag aaccgcattt ctcataataa tcgtgagtta
     2341 actgatagcc aaaaaattaa tagtttgtct ggtagaaaat aattagcaga tttacaagtg
     2401 ggaaataaaa agctgaaaga agaaaattgc atttcaaact acattttcta caataactct
     2461 aaaatggcat attttgcgtt ctgagcggtt ttagcgttta tttcgtttag ttatcggcac
     2521 aatcggtgaa acacgttaga ggagcgaaaa tggagcctgt aaggcgactg gtagcggaac
     2581 ggtcgtgtta gattgtgtag ccgatagctg aacgaaataa atgctggcag cgccattcta
     2641 tttcggcagg aggaggctca aggggttcgg ggaatgaaat tccctgaggt ctttttattt
     2701 tttctagagg agtgctataa tcaaagaaaa tgagaaaaaa gagt
//
LOCUS       DAFELK010000131         2721 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFELK010000131
VERSION     DAFELK010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.141"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(247..468)
                     /locus_tag="LP433_002907"
     CDS             complement(247..468)
                     /locus_tag="LP433_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007002.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(566..811)
                     /locus_tag="LP433_002908"
     CDS             complement(566..811)
                     /locus_tag="LP433_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007003.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1051..1665
                     /locus_tag="LP433_002909"
                     /pseudo
     CDS             1051..1665
                     /locus_tag="LP433_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2035..>2721)
                     /locus_tag="LP433_002910"
     CDS             complement(2035..>2721)
                     /locus_tag="LP433_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBL2007004.1"
                     /translation="NSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSK
                     DNIRRFLTKKVNYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIF
                     DPIEFDNDERLLLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKL
                     SKSGILKEEYDSSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPF
                     SNLDESDLPF"
BASE COUNT          910 a          477 c          369 g          965 t
ORIGIN      
        1 ttttactata tacttcttcc cagaacttgt ccgtctcctt caaattatct ctacctctcg
       61 agttcattgg gtggtttgcc catttattaa acatggaatc acctttctca tactcatata
      121 tttatgtcct atttcaatta tatttatata tgcttaaata aatttgtatc ctgaaattta
      181 ttgtaatatg aagctgtatt ttacatatag taaccaaaga gttaataaaa taaaaagagc
      241 gaaccattat agatcagctc ttttttcatt gctgttttta atcttatcta gaatcacttc
      301 aaatgtttca aaggtattta catctaactg acataaccaa agcaagtact tcttttcttt
      361 gtaagtccaa tcaatattac ggtaagagga cattagatta tggtaccttg ctctttgttc
      421 aactgaagcc aattcccagc gtttttcaaa tattttttct tcttccatta ttgatccctc
      481 gcaagacgct acctcaaact taaataatgg gcagcgaaag tctaattcct tagatctaag
      541 tatagcaaac aaatatgaaa aaaacttaga aggtagtaaa agttcttccg tcttttgctt
      601 tgcttctatt cttaatgtgt ttcgttatcg gtgccctaca aagattttca ttaattacac
      661 actcatttat tgttgtgtat tttctgacat ttctctcttg atcaattatt ttaattccat
      721 gggcatcctg atagttcata ggagaggagc ggctatcaga aatagttgca cctatctctt
      781 gaacttcttt tacaacttct ggaaaatcca tccatcctgc ttcagctgtc aaaagtaata
      841 atctataata tttatctttc cttttcaatc taagaaatcg tcaccccatt ctttttcttc
      901 tattataaac tatttaactt ttagaattca aaaaccgttt gtctatttag agtttaccct
      961 aaatagacaa aaatataaca ttgaaaaatt tagagttcta acgtatgatt agggtgtatt
     1021 ataaacgtta tagaaaagta gggaataaat ttgaaaattg cttatattag agtttcatcc
     1081 atcgatcaaa atgaacaacg tcaaattgaa gaaatgaaaa agtttggcgc tgaaaaaatt
     1141 tttatcgaaa aacaatctgg agcgacgatt agtcatcggc cgattttcca ggaagcttta
     1201 gattttgtca gagagcaaga tatttttatt gtagaagcca ttgatcgact tggacgcaat
     1261 tatgacgaga ttatcgattc agtgaattat ctaaagaaga agaatgtgcg acttattatc
     1321 accagtttac cgatcatggc tgaagcaatt ggaaatcctc tcctagataa attcatcaaa
     1381 gacttaatca tttaaatctc agccatgatt gctgaacaag aacgtactga atcgaaacga
     1441 cgccaggcac aaggaattaa aatcgctaaa gcaaacggcg tctataaagg tcgtcctaag
     1501 ttatacagtg cagacaccaa agatcctcaa cgtcgccttg tctataggag tatcgttcag
     1561 gatcttgaga atggggttgc tatctcaaag attgcaacag actacaatgt gactaggcaa
     1621 acaatttacc gaataaaaaa agaaatcgac caactaattg tatgatttct tttttgaatc
     1681 acgtaattat taattagctt tgtcatcaat acagacaatc attttagatt catctagcta
     1741 agttgattac atttatgtta aaaagaattt agttaacata aatataattg atgcataaat
     1801 cgtccttatt taaaggcatt taacattgac aacttagtat aatgtatctt atgtaaacta
     1861 ataagatttg aattttattt tatacacact cgataataga tcaattttat ggtcccccgc
     1921 atttacgatt gcacaagaga aacataaagt cgacctatta gcatttcttt tcaattcaaa
     1981 cattaaaaaa gtttatacct ctgctactaa aaaatgaaat tatctattta aaatttaaaa
     2041 cggtaaatct gattcatcca aattggaaaa tggatcagcc tgtattggag ctttgtattt
     2101 ctccataata acagatatct ttttttcatt ttttaaaaaa taccttttaa atttcttata
     2161 gtcctctgaa atcaaaatat agcgtgatgg atactcatca aaagaagaat cgtattcttc
     2221 ctttaaaatt cccgatttac ttaatttttc tagtacatca aatactctat cactcaagta
     2281 actccttaaa ttgttatcac tttcccattg aactactttt ctataagttg aattatcagt
     2341 tgaaaagata gaattttcat ccataaacgc atatattagc agcaatcttt catcattgtc
     2401 aaattctatt ggatcaaaaa tatctaagtt gtcatcaaaa tctttatcag ttccggtaac
     2461 ttttttgtta attactgaag gtgtcttgta agaaatagaa tctaaatcaa agcgttttga
     2521 ttctaaatta ttttgtgctt tctcaattaa ataattcact ttttttgtga gaaaccttct
     2581 gatattgtct ttgctatatg ttccataaaa acccttatct tctaaagagt ccctgtactt
     2641 cttaacttct atatactctt cagccaaaac ttgtggaact ggttcatcta agaaaaaaac
     2701 ccctacctcg cctttgctat t
//
LOCUS       DAFELK010000132         2652 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFELK010000132
VERSION     DAFELK010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.142"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            137..748
                     /locus_tag="LP433_002911"
     CDS             137..748
                     /locus_tag="LP433_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL2007005.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="LP433_002912"
     CDS             821..1750
                     /locus_tag="LP433_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBL2007006.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1819..2645
                     /locus_tag="LP433_002913"
                     /pseudo
     CDS             1819..2645
                     /locus_tag="LP433_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
BASE COUNT          930 a          369 c          493 g          860 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aa
//
LOCUS       DAFELK010000133         2473 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFELK010000133
VERSION     DAFELK010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.143"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            7..624
                     /locus_tag="LP433_002914"
     CDS             7..624
                     /locus_tag="LP433_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007007.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
     gene            1644..>2473
                     /locus_tag="LP433_002915"
     CDS             1644..>2473
                     /locus_tag="LP433_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2007008.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          905 a          326 c          397 g          845 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagagc aaatataaaa tttaatgaaa atatagaact aaataggaaa
      781 acgtagacgt aattttctac gttttccttt tcatatatat taaatattac ggaaaattat
      841 ataaactaat ttagtgtttt gtttgtaatt cctaattttg ctccactttt agataatttt
      901 taggtctatt taactcatca gacattctat gctcattttt ctccaaattt gtttcaactc
      961 tttcgtactt aattttgcgt atttgaaaat tcttctttta gagtactttt attacgatac
     1021 tagtatgata tatatctata gcaaacagtt aaaatcttcc taaaataagc gaatagcatt
     1081 cctaaaacct ataaaatttt tagatgaagc gacaagtgga caattaataa actacttgaa
     1141 catgaaatta tggatcacct ttcaaattta gaaaatggaa ttcttatact tattgcgcaa
     1201 catttattga ttgcaaaatt atgtgacaaa aaaaactagt agaagaaaga ataatggctt
     1261 gataataaag tactacctat taaaggtagt actttattta atttagtata aattaacata
     1321 ctactatatt ttaggtttca tattatataa attaataata tactaccatt tgttggtagt
     1381 ataatttaaa ggtaataagt tattctttta ttactatgtt tgggttttat agcaaagaaa
     1441 gtttaataag agtttggacc tagcaaacaa tattaatgag gtcattaaat cttattatct
     1501 ttagtgatat aacgaaatat ctacacagac aaaatgatag cgtaaaatat tttgtgtaaa
     1561 tagatattta gggtagaaaa aaagaaagtc cattctgtaa aattaaagtt accacaaccg
     1621 aaattttata ggaggacttt ctcatgccca attttactac agaaattatg gaaacactaa
     1681 tcaataaagg tgatttagat gaattatttc gatgtcattt agaattagct gttaattcat
     1741 tattgcaggc tgaattaaca gcttttcttg attatgaaaa atatgatcgt gctgggttca
     1801 attcaggtaa ttcccgtaat gggaattatt cacgttcatt cagaacagag tatggagaat
     1861 taaatttggt aattcctaga gatagaaatg gtaagttttc tcaacaaact ttacctgctt
     1921 ataaaagaac caatgactct ttagaaacca ctattattca gctatttcaa aaaggaatta
     1981 ctatgtctga aatctctgaa ttgattgaaa aaatgtacgg gcatcactat acgccacaaa
     2041 ccatttcaaa tatgactaaa atagtttctg aagatattat tgcctttaaa gaaaggtcct
     2101 tagaatccag atactctgtc atttttatgg atgctactca cattccttta aaaagacaaa
     2161 ctgtttcaaa agaagcagtt tatattgtaa ttggcattcg attagatgga accaaagagg
     2221 ttcttgggtt tagtcttgct ccaactgaat ctgcttatgt ttggaaagag attcttcaag
     2281 acctaaaaga ccgtggttta aaagaggttt tattagtcgt aactgatggt ttaagtggca
     2341 ttaacgatag tattcatagt gtttatccaa atgctcaatt tcaacaatgt tgtgtccata
     2401 tatctagaaa tatcgctcat aaggttcgtg ttagtgatcg acaagaaatc tgtagcgatt
     2461 tcaaattagt tta
//
LOCUS       DAFELK010000134         2441 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFELK010000134
VERSION     DAFELK010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.144"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..280)
                     /locus_tag="LP433_002916"
     CDS             complement(<1..280)
                     /locus_tag="LP433_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HBL2007009.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTH"
     gene            742..2124
                     /locus_tag="LP433_002917"
                     /pseudo
     CDS             742..2124
                     /locus_tag="LP433_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          881 a          428 c          411 g          721 t
ORIGIN      
        1 aatgagtata gtatgaatta gtaatttggt tttcatctaa gtttagcttt gatttactaa
       61 aattgatatc tcgatacatg ttcaatacat ctaatacaaa tcgagaatct tctttcggaa
      121 atggctcaga aagatcactc caaatttcat catcataatg atactcgtaa ccttctctca
      181 atatttcgat ttttctttca taataagatc tgttttggtc ctcaaattta gccaataact
      241 caaattgatt tactagtgac aatctctgaa aactgtccat taaatgtttc ttcctatctt
      301 gttcattaac aaaaaattat aagcccttac aacgaatatt atatattaaa tttaattgta
      361 ggtgaacacg aattttataa atatttatgg tgttaatgac aaatgatatc cgactcctct
      421 tcatacgttc tggactattt gctaatagat taaaatttca gcatctattt ctgaccataa
      481 ataaatgagc tgccgaaaag ctgccaaatc agacttgaaa ataaaggatc aaaaactttt
      541 aagtttctga ccccgtaact cacacttcaa aatcttactt aaaaaggagt ctgaaagaaa
      601 aaaagagtat tcaaaatttt tttctaacta gctacatcac atctatgcat tgacactcaa
      661 agaaccagaa taagtcatca gaaagcaagg gggtgcggac ataatcctgg acgaaaaaat
      721 aaacttagga ggaatgtccg tgtgttttcc cacaaagagc gtgtaagggc aattcagtta
      781 tttttaaaat acgattgctc ttatgctgca accattcgag aattagggta tccgtcgatt
      841 ggtgcactac ggaaatggta taaagagtat ttggaatccg gagagctcca tcaggagcac
      901 cgaaaaaaat caaagtattc tgaagaacaa aaacgaatag cggtgaatca ttattttgaa
      961 tatggtcaat gttatgcacg aaccattcgc atgcttggtt atcctaatag agagtccttg
     1021 cggcagcggt gtgaagaact tgcaccagga gctagaaaac tccgaaaaag tgcggtaaag
     1081 ttaacacaag atcaaaaaga agctgtgttg aaaaaattct ataaaccgca aactaatagg
     1141 aaaaatttag ccgaatctgg aggaattagt agagttactc tatatcaatg gaaaaacacg
     1201 gttcttggaa aggattttcc attgtgtatg actttaaaaa atcaggaaaa acaaaaagag
     1261 ctacttttaa aggaagtaga agacttacaa aaacaagtac accaattaca gctcgaaaaa
     1321 gcattactcg aaggagcggc tgaactgcta aaaaaagaaa aaggcgtcaa tcttctttgt
     1381 ctatcaaatc aagaaaaaac gatattgatt gatgccttac gaaatcagtt caccttgaaa
     1441 gagcttcttc aacagctcca gtttcctaaa agcagctatt tttatcaaaa acaagcactt
     1501 gagaaaccag ataagtatta caaagaacgt caaattaatt atcacgattt tcaatcataa
     1561 cttctgtgcg tatggttacc gtagaattca ccaagcttta aaaaatatgg gtaaaaagct
     1621 ttctgaaaaa gttgtacgta gattgatgac tgaggaaaat ctatttgtta aattttctag
     1681 acgaaaaaag tattcttcgt atgctgggga aatttctcct gcacacccca atttattaaa
     1741 tcggaatttt aaagcaaaga agccaaatga aaaatggtta acagatatta ctgaatttag
     1801 aattctcgca gggaaaatct acttatcacc acttgtcgat tgttacgatg gtgctattgt
     1861 tagttggact attggaacaa agccaacttg cttcactcta tgtctaaaaa gagttattca
     1921 ccagataatt cagcgtgcga aggtttcttt ggacgattaa aaaacgagat gttttatcaa
     1981 cgtgactgga agaatacaac aatcaatcag tttataaaca aattggatga ttatattcat
     2041 tggtataata atcaacgaat taagttatct ttaggaaggc taagccctct tcaatatcgg
     2101 aagaagcaaa gatatatttg ttaaaaaggt ccaaaaaaaa tatccgcacc cccttttttt
     2161 tgtaaaaaac tattgcacaa tacaagtagc ctacggctat cgaaatttcc ataactttcg
     2221 agcaagaact tatctcattc aaggcttgat cttccaagta aaacaaaaac cagttaagca
     2281 ctctgcctaa ctggttatga ctaaattttc agttgtatct ttctctacca acactaaatg
     2341 tcgaagagcc ttttttcgtt tatgaatgta agaccgcttc tcgagccaat gccaaacaac
     2401 cgagcgttcc agcgttgtct tctaatgctg gggtcacgat a
//
LOCUS       DAFELK010000135         2398 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFELK010000135
VERSION     DAFELK010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.145"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            207..2069
                     /locus_tag="LP433_002918"
     CDS             207..2069
                     /locus_tag="LP433_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2007010.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="LP433_002919"
     CDS             2069..>2398
                     /locus_tag="LP433_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2007011.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAFELK010000136         2318 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFELK010000136
VERSION     DAFELK010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.146"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..181
                     /locus_tag="LP433_002920"
     CDS             <1..181
                     /locus_tag="LP433_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007012.1"
                     /translation="GVKPNTIKPSEYQALELTYGKFVETKKAKTVSSEWLDYLENVNK
                     YGACYIMKKEDNENE"
     gene            174..869
                     /locus_tag="LP433_002921"
     CDS             174..869
                     /locus_tag="LP433_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007013.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            1250..1429
                     /locus_tag="LP433_002922"
                     /pseudo
     CDS             1250..1429
                     /locus_tag="LP433_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1491..1675
                     /locus_tag="LP433_002923"
                     /pseudo
     CDS             1491..1675
                     /locus_tag="LP433_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358324.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            1709..2140
                     /locus_tag="LP433_002924"
     CDS             1709..2140
                     /locus_tag="LP433_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBL2007014.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT          824 a          361 c          475 g          658 t
ORIGIN      
        1 aggcgtcaag ccaaacacta tcaaaccttc tgaataccaa gctttagaac taacgtatgg
       61 gaaatttgtc gaaacgaaaa aagccaagac tgtttcaagt gaatggttgg actacttaga
      121 aaatgtcaac aagtatggcg catgttacat catgaaaaag gaggacaacg aaaatgaata
      181 aggtgattta tcaactaaca acggaagatg tgtcacactt tttaacaaac aaagaacatt
      241 tgaatgaagt aatcagacgg attcaaaaag actttagttg tatggaagaa atgaagtact
      301 ttattcaaag agtcgaagaa caattgtatt tggaaagtga aacgagtcaa acgaaggtta
      361 cagtcagcaa taattattta gacgtgtata aacgtcgtcc tgacacatta aaaaaaggag
      421 cggagcttct acgactagaa acagaaaaat atatcatgaa tgtttaccta gaaaggagtg
      481 aactggtcga aaactttgtc agctacacga tttgcaggaa acactattac tcagaatcag
      541 aatattattc aatttttgag agcatggaat taatggaaga gctaaacagc aaagatgcga
      601 cggtagacga ttattacctt gtatttacta aatttttgac gtgtgggacg gaatctatcg
      661 tgttaatggg aatggattat gaactcgctg tacccgaagt atttttgagg gaatatgtag
      721 aagaagtaga taacccaggc gacgactggt acacgacttt aactgatttt ttagatacct
      781 acacttacga cgatacagaa gaaatccaaa atgaacttga ccgtaaacga atgccatatc
      841 aacgatttga aaggaaaaaa ggtcaataac catttatacc gaaaagtgag aatgtgtgaa
      901 ataaaaacaa aaaaccttga aattaaggga atggttctta tttcgcacca atcgctccaa
      961 ccgcccccgc cgcttaggtg gtgcgaaata agcgagcaaa gcccgaaaac ctaagagaaa
     1021 gaaggagatt tatatgaaca aaattattcc cttattatta gtcctatttg ttggagaaat
     1081 acttatgcga cttagtgcag ctgtacattt aaacctcgca gtatttttgg taatactaat
     1141 gttttgtttg atcttttggc gatttgtatt agccctcgta agtctactat tcaagatgat
     1201 tgcagccata tttttcatag gattatttcg atgaaaggag agagtaccaa tgccaattgc
     1261 aataggaaat aaacggttac ccgtgacgtt ggatgaaaag agacaaaaag aattgcagta
     1321 accaaagcag aagtacggca aaagtgaatc caggattatg tgtattgcgt tagatttatt
     1381 gattgcgcaa gaaaaagcag gatttgacat accagcactc aaaaagtgat cgcactttgc
     1441 gcacgtgtta atacgtgtta taattatttt gtaaggaggt atagtgcaca atgccactta
     1501 cgggaaaaga aatgcttaag ttattgaaaa aaatggctgg gttgagcgaa ggcaagaggg
     1561 atttcatcat catctttata aggatggtgt tagaatcact gttcctgttc atgccaatca
     1621 agatcttggc cgaggacttg agcgaaaaat tttaaaggat gcgggattga aataatctcg
     1681 cattcgatta aagaaaggat tgactgaaat gttaagtgag cctttagcaa aaacctatcc
     1741 tgctattttt agcccagaag aaggtggtgg gtactttatt gaatttcctg atgttcaagg
     1801 tgcttacaca ggaattaacg aagacgatat atcttatgga attgctatgg cacaagaggt
     1861 gttaggtatg gttttagcag attatattga gcatgaagat ctacttccag aaccaacacc
     1921 aatcaataag atttctgttg aagatgattc ttttactact ttaattcgtg tagatgttgc
     1981 caaatatttg aaagacacag aacttgtcaa aaaaacctta acaattcctc aatgggcgga
     2041 taagctaggc aaaagggctg gcataaattt ttcagtcctt ctaacagaat caattgcaga
     2101 taaagcagat aacattcttc gttctggaag aaataattag aactcaaaag ggtcagaaac
     2161 ttaaaaatct ttggcttctt tttttactac aaagatggct tctttaaatt atttgcctga
     2221 ttgatttaaa aaaattgcgc aaagactacg agctaattaa gttgctcgtg gtcttttttt
     2281 atgaaaactt tttagatctt attatttgtc aaattaag
//
LOCUS       DAFELK010000137         2270 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFELK010000137
VERSION     DAFELK010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.147"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            191..445
                     /locus_tag="LP433_002925"
     CDS             191..445
                     /locus_tag="LP433_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2007015.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="LP433_002926"
     CDS             446..763
                     /locus_tag="LP433_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2007016.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="LP433_002927"
     CDS             1322..2257
                     /locus_tag="LP433_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007017.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          429 g          711 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag
//
LOCUS       DAFELK010000138         2220 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFELK010000138
VERSION     DAFELK010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.148"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(51..1598)
                     /locus_tag="LP433_002928"
     CDS             complement(51..1598)
                     /locus_tag="LP433_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL2007018.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="LP433_002929"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="LP433_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL2007019.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..>2220)
                     /locus_tag="LP433_002930"
     CDS             complement(2043..>2220)
                     /locus_tag="LP433_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007020.1"
                     /translation="IVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIYNGINNY
                     ILQAILKELLSNAL"
BASE COUNT          622 a          465 c          397 g          736 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
//
LOCUS       DAFELK010000139         2072 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFELK010000139
VERSION     DAFELK010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.149"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..619
                     /locus_tag="LP433_002931"
     CDS             <1..619
                     /locus_tag="LP433_002931"
                     /inference="COORDINATES: protein motif:HMM:TIGR00350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2007021.1"
                     /translation="VDIIGYDTYDKINHAYAFGGVAMTINTIQAYLDIPIDFFVTLNM
                     QGLEQIVDSIGGITLTPTATFTQDSYSFYQGEIINLDGKASLAYSRNRHADDSGDYGR
                     QARQREIIMAIIEKGTKVTTLATKIPSLIKSLQGNMTTNLSVDDMWTIINKYSTALGN
                     IEQVQLKGEGQLLDDGIYYEMINEESLEEVQNILQKQLDYHLNID"
     gene            669..1193
                     /locus_tag="LP433_002932"
     CDS             669..1193
                     /locus_tag="LP433_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007722706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2007022.1"
                     /translation="MQNDIRGKIKKSRHIKGISQSEVAKYLNISRQSISKWENDTSSP
                     DINNLTLLSSLYEISIDDLLKEKKEVKKNIKENSIEIIESKNKLIYLKNNTNRDEGLV
                     LLLISLIGCLISPLGLIIAPVVLKRNKATNTFYKGVIAASVICFTVSLFVSYGHFSNI
                     FHWGGSTNVEYIEN"
     gene            complement(1190..1654)
                     /locus_tag="LP433_002933"
     CDS             complement(1190..1654)
                     /locus_tag="LP433_002933"
                     /inference="COORDINATES: protein motif:HMM:NF037267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5626 family protein"
                     /protein_id="HBL2007023.1"
                     /translation="MRQVLLVVTLCLSFFLFEVNTVEAYVANNGVYYNLIQGGTQEFM
                     EVDEEGNPILIRVEEVPGLSLFSVNNGNYKISGSKFGMWKANYYVTVSNNQFIRAYSP
                     SAVAVTGSFTSTRLSLVSSKKASYTLEWKAGILSSNSYLDATLTDNSINITY"
BASE COUNT          766 a          330 c          343 g          633 t
ORIGIN      
        1 tgtcgatatt atcggttatg atacttacga caaaattaac catgcctatg cctttggtgg
       61 agtagccatg actataaata caatacaagc atacttagat atacctattg acttttttgt
      121 aacgttaaat atgcagggtc tagaacaaat tgttgattct attggaggaa taactcttac
      181 tccaactgcc acttttacac aagatagtta ttcattttat caaggcgaaa ttattaactt
      241 agatgggaag gcttccttag cgtactctcg aaatcgtcat gcagatgatt caggtgacta
      301 tgggagacaa gctcgtcaaa gggaaataat aatggcaatt atagagaaag gaactaaagt
      361 tactacacta gcaactaaga taccttcact cattaagagt cttcagggaa atatgactac
      421 taatctgtca gttgacgata tgtggactat tattaataaa tattccactg ctttaggaaa
      481 tatagagcaa gttcaattaa agggggaagg acaactactt gatgacggaa tatactatga
      541 aatgattaac gaagaatctt tagaagaagt tcagaatatc cttcaaaaac aactagatta
      601 tcacttgaat atagactaaa taatctattt cttaatatcc aataaataaa agtcattaat
      661 aggagaggat acagaatgac attaggggaa aaattaaaaa atcacggcat ataaaaggca
      721 tctctcaaag tgaagtagca aaatatttaa atatatctag acaatctatt tctaaatggg
      781 aaaatgatac tagttcccca gatataaaca acttaacttt attaagtagt ttatatgaaa
      841 tctctatcga tgatctttta aaagaaaaaa aagaagttaa aaaaaatata aaagagaata
      901 gtatagagat aatagaatct aaaaataaat taatttattt aaaaaataat acaaaccgag
      961 atgaagggtt agttttattg ctcatttcct taatcggctg tttgatttct cctcttggac
     1021 taattattgc gcctgttgtt ctgaaaagaa ataaagcaac aaacactttt tataaaggag
     1081 tgattgctgc ttcagtcatc tgttttacag taagcctgtt tgtctcctat ggacatttta
     1141 gtaatatctt tcattggggc ggctccacta acgtggaata tattgagaac taatacgtaa
     1201 tattaatgga attatctgtc agtgtagcat ctagataaga gttactagat aaaattccag
     1261 ctttccattc taatgtgtag ctagcttttt tgctggagac gagagacagt ctcgtgctag
     1321 taaaggatcc ggtcactgcg actgcagaag gggagtaggc cctaataaat tggttattcg
     1381 agactgtcac atagtaattt gccttccaca ttccaaattt agatccagat attttataat
     1441 ttccgttgtt gacggagaac agggagagcc cgggaacctc ttccacacga atcaagatag
     1501 gatttccttc ttcgtctacc tccatgaact cttgcgtgcc accttggatt aagttatagt
     1561 agactccatt atttgccaca tatgcttcta cagtgtttac ttcaaataaa aagaaagata
     1621 aacataaagt aacaaccaat aaaacttgtc tcaaaaaatc cctcctaaaa ttaatatact
     1681 catagtttaa tatatacggg tttaattagt aagagaacat tttgtgaaca ttcttatatt
     1741 gaaacggctc tctctacaaa tggacgcata tataagtgta tctgggttag taaacattca
     1801 ctgttaccaa ctctacttac taaacagata aaatatcaac gaaataaaaa aaccaaatca
     1861 actaattttt tactaataac gtagataata aaatcaaaaa gcaaatttga gcggttgcaa
     1921 ctataaagtg acctgatgta aaccataaga tgcttaatta agctatactt agatgagaca
     1981 ctatacttag gaagaactta gattagcata gcttcctaga acaaaaaaat acgagaggaa
     2041 gattctttta tgactaataa atatctatct gt
//
LOCUS       DAFELK010000140         2003 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFELK010000140
VERSION     DAFELK010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.150"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..378
                     /locus_tag="LP433_002934"
     CDS             <1..378
                     /locus_tag="LP433_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBL2007024.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="LP433_002935"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="LP433_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBL2007025.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2003
                     /locus_tag="LP433_002936"
     CDS             1859..>2003
                     /locus_tag="LP433_002936"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007026.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          555 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tta
//
LOCUS       DAFELK010000141         1788 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFELK010000141
VERSION     DAFELK010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.151"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            86..652
                     /locus_tag="LP433_002937"
     CDS             86..652
                     /locus_tag="LP433_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2007027.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            797..884
                     /locus_tag="LP433_002938"
     tRNA            797..884
                     /locus_tag="LP433_002938"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:829..831,aa:Ser,seq:cga)
     gene            1218..>1788
                     /locus_tag="LP433_002939"
     CDS             1218..>1788
                     /locus_tag="LP433_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBL2007028.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGFHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT          615 a          273 c          350 g          550 t
ORIGIN      
        1 ttttgagtaa aatgtttgca aaaaatgcta aaaatagggt acaataaaac aacatatact
       61 gcagtaaaga agtgggggag ttttaatgag aagaaaagtc tataccaagg atcaaattct
      121 aaaagctgct tatgatgttg ttgcaaagga agggtttaaa ggatttactg cgagaaatat
      181 tgctaaaaag atggggattt cgacacagcc gatttatctg gaattcaaaa acatggaaga
      241 tttaaaaaat acgttgctgg attctatctt tgaacaacta aaagaagatg ttttccctat
      301 tgaacgtact ggtgataaaa tcattgatct cggtttgaac tatatctact ttgcaaaaaa
      361 gcatcatagt ctttacatgg cattgtacat tgatgaacat ggggacggaa agaaaatgca
      421 tgatttttca tacaattatt tccgtgaaat agttaaagaa gatgaaagat acaatcaatt
      481 atcggatgaa tatgtcgatg ctctgcatac tggtacatgg gtagcagtga ctggcttagc
      541 gtcattgatg tcatcaaaca tcatgcatcc aacagaagaa caaatcattg cactgatcaa
      601 acggacaatt gactcgattt tagcattaga taatcctgaa ataatcagat agtgttctat
      661 cagtatgaat ttgatcggta agtccgttgg ctgcaaactg tcaatggact tttttgctaa
      721 aaaaagcgat ttctgttatt tatctattag aaataggctt gacatttcgt gaaaaaagtt
      781 taaaaatagt acttacggaa ggttggcaga gtggtaatgc accggactcg aaatccggcg
      841 aaccggctaa taccggcgcg caggttcaaa tcctgtacct tccttatatc aacgattaga
      901 ggttgtgaag aagctgtcct gcatcaagta ataagaacgg ccaaacaaaa atagcttttc
      961 ctattttttc gtttgattgg gcttattacc gcagatgcaa gcttttgaac accgtttgtt
     1021 cggaataagg ggctgtgaca agacttttgt cacagcccct tattgttgta cttttaacct
     1081 acaatatttt ttgattcccc ctgagtacta ttttttataa atgctagtaa atcaatcttc
     1141 tttggccttt ttttgataaa aaaaatacta gatgtaagat aaaagtgtaa aaacgatttg
     1201 ttttaggagg ggaaacgatg tgtaccgcaa tcacttatgc aacgaaagac cattattttg
     1261 gaaggaattt tgattatgag atgtcttata atgaagtggt cactattact ccaagaaatt
     1321 atcgtttcga ttttagaaag gtaaaaaatt tagataaaca ttatgcaatg ataggaatag
     1381 cagctggggt atccaactat ccactctatt atgaggctac aaatgaaaaa gggttgagta
     1441 tggcaggact gaattttcct ggcaatgctg attataaaga attacaagaa ggaaaagata
     1501 acgttgcacc atttgagttt attccatgga tactagggca atgctcaacc atagacgaag
     1561 ctaaagaatt attggctact atcaatctag tcaatatcga ttttagtgaa aaactaccct
     1621 tgtcaccttt acactggtta ttagctgata aagaaaaatc gatagtaatt gaaagtatga
     1681 aagatggatt tcatttatat gataatcctg tcggtgtgtt gacaaataat ccgccatttg
     1741 attatcaatt atttaatctg aacaattatc gctcgctatc aaatggaa
//
LOCUS       DAFELK010000142         1435 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFELK010000142
VERSION     DAFELK010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.152"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..290
                     /locus_tag="LP433_002940"
     CDS             <1..290
                     /locus_tag="LP433_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007029.1"
                     /translation="GYRCYKMSYYVSPSKCKQLARQTNKLNTVSAIANFIGLSGLTPG
                     IISLVFGSAVSANNVFVTAARRGKGVQLNYIAHFSNTTTYNYSSNQNYVIK"
     gene            320..484
                     /locus_tag="LP433_002941"
     CDS             320..484
                     /locus_tag="LP433_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007030.1"
                     /translation="MKLTKIAVILAVIAGIILYFVLPANQFFLYFGIPAILIVNGVRI
                     FEQRKKCSST"
BASE COUNT          429 a          238 c          279 g          489 t
ORIGIN      
        1 ctggttatag atgttacaaa atgagttatt atgtaagtcc ttctaaatgc aaacaattgg
       61 ctcgccaaac taataaactt aataccgtct cagctattgc aaactttatt ggactatctg
      121 gattaacacc ggggattata tcattagttt tcggatcagc agttagtgct aataatgtat
      181 ttgttacagc cgctagaaga ggaaaaggcg ttcaattaaa ttatattgcc cattttagta
      241 ataccactac ctataattat agttctaacc aaaattatgt tataaaataa ttaaaacttt
      301 aaactaggag gaatgcttta tgaaattaac aaaaattgct gtaattttag ctgttattgc
      361 tggcattatt ttatattttg tattgcctgc taatcaattc ttcctttact ttggaatacc
      421 tgcgatttta atagtaaatg gcgtaagaat ctttgaacaa cgaaaaaaat gtagctctac
      481 ctaatcgtta caaaacaaca atttcacctt cggtgaaata agcgaaactt tacaaaaagt
      541 ggctagcaaa tgctagccac tttttgtatt gtagagcgtg aattttgagg gggattcaag
      601 ggggagcttg cgcccctttg acaagcggtt atttgcacca aatacctccg tatttggcta
      661 gcaatccttc taaaaaatac acctatcgat cagagtcaaa acaaatcaat tttcgagtga
      721 gcgaatccga atttgcaaag ctgaagcttt gcaaatgagt gtgccggctt ccgtaaaaat
      781 acatatggct ataatttgcg ttttaaggcg ttttaaacgt tctggtatat aattatacca
      841 aaacaacttt aaaacgcctt agatctaatt ttagaggtct tatagaacat tttagggttg
      901 ttagggcttg ccctgaccgc ctgtaaggcg ctttgagaac aagataaggg ttttatacta
      961 agactgtctt aaaacggctt aaacaaacgc tcagaacttt tcaaaggagt tctttatgaa
     1021 ctgtttttaa gcaaaggagc ctttaggcga ctgcgcagta taatgtgaga gcgtagcgat
     1081 cacacatttt tagtgaccgt agggagcgag tttcccagtt tagaaaaatt cgcgaacttg
     1141 tttgaggaaa aaagcaggag ttttttaggc gggaaatttt gcctcctctt ttataatctc
     1201 tttttaaacc tctttttaaa cctctttacc gtcggctgta tgcttactct cccaaggtgt
     1261 gcagaatctt ttgggggtct ttttgtctgt ttttaggggt ctttttgtct gtttttgggg
     1321 gtctttttgt ctgtttttag gggtctttaa ttaggggctt gacccctatt agaaagctct
     1381 ttataatttt gttaagtagt taatcttgaa ggaggatttt atggcaaatg aaatt
//
LOCUS       DAFELK010000143         1424 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFELK010000143
VERSION     DAFELK010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.153"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..537
                     /locus_tag="LP433_002942"
     CDS             <1..537
                     /locus_tag="LP433_002942"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007031.1"
                     /translation="VMAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNG
                     QPMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEEIKEMGYNKYGGLD
                     MTIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQA
                     IIDSGRVTQWKKIRPFIF"
     gene            564..>1424
                     /locus_tag="LP433_002943"
     CDS             564..>1424
                     /locus_tag="LP433_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007032.1"
                     /translation="MNENGEFEESKKYQATSEEEKAAVRELLEEAVPTDFLKEKENDH
                     FYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYYKFYFEEVKNGEVV
                     DQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKEQMQSKETKTKQKG
                     YQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFPERSFRNQLLIEEQ
                     FPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGFVREIEATPEDKKR
                     IESGQIEVIKK"
BASE COUNT          590 a          223 c          318 g          293 t
ORIGIN      
        1 gtcatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccagaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gagcgaatcg aaaataaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacaa
      241 gtagaaaaac ttgaaagaca agaagagata aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgagaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc ggaaaaagga aaagaaaacc ttcttcctga agtacaagca
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaatcc gaccatttat tttctgaaag
      541 gctatcgaaa agtcgcttta gaactgaatg aaaacgggga atttgaggaa tctaaaaaat
      601 accaagccac gtcggaagag gaaaaagcag ctgttcgtga attacttgaa gaggctgtac
      661 caactgattt tttgaaggag aaagaaaacg atcattttta tcgagtagaa ttcaacgaaa
      721 atgatccaga aaaaggattg aaaagttatg gtggggagat cgtaacattc gaattgatcg
      781 atcaactcaa aacgttggat aaccaatacg ccgcagaagc aggttattat aaattctatt
      841 ttgaagaagt gaagaacgga gaagtagtcg atcagatccg aatggatcta ggggatggcg
      901 tcaacagtaa tcaacccatc tatttagagt tagcaaaatt gtgcgaacaa gtacctgaga
      961 aggaacaaaa acaatcggtc aaaaatgaac ctgtttcgaa agaacaaatg cagtcgaaag
     1021 aaacaaaaac aaaacaaaag ggctatcaaa aacgaacggc agaagagatt aaacaagaag
     1081 ttaaatccct ttcgcaacag gcactggatg cggtgaaaaa gcatactcat tctcctgaag
     1141 acgtcaaaga acttttgaac tttatgtctc gttttccaga acgatccttt agaaatcaat
     1201 tattgattga ggaacaattt ccaggtgcaa cggcttgttt aggtcgtgcc gcgttgaaaa
     1261 aagaaggaat ctatatcaaa aaaggggaac aagggaacaa gatctttgtc agaaaaacgg
     1321 tcaaaggatt ttatgagaaa ggacgtggct ttgttcgaga aatagaagct acaccagaag
     1381 ataaaaaacg aatcgaaagt ggtcaaatcg aagtgatcaa aaaa
//
LOCUS       DAFELK010000144         1424 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFELK010000144
VERSION     DAFELK010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.154"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(150..1337)
                     /locus_tag="LP433_002944"
     CDS             complement(150..1337)
                     /locus_tag="LP433_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBL2007033.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAFELK010000145         1381 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFELK010000145
VERSION     DAFELK010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.155"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            82..1377
                     /locus_tag="LP433_002945"
     CDS             82..1377
                     /locus_tag="LP433_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HBL2007034.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIKVR"
BASE COUNT          474 a          257 c          261 g          389 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa gctccaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcgatgatct atccttacac caatggaaaa
     1261 atagaagcga agaataccca tataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatcaaagt aagataacaa
     1381 a
//
LOCUS       DAFELK010000146         1370 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFELK010000146
VERSION     DAFELK010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.156"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            78..193
                     /gene="rrf"
                     /locus_tag="LP433_002946"
     rRNA            78..193
                     /gene="rrf"
                     /locus_tag="LP433_002946"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            203..276
                     /locus_tag="LP433_002947"
     tRNA            203..276
                     /locus_tag="LP433_002947"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:237..239,aa:Asn,seq:gtt)
     gene            316..405
                     /locus_tag="LP433_002948"
     tRNA            316..405
                     /locus_tag="LP433_002948"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:350..352,aa:Ser,seq:gga)
     gene            420..491
                     /locus_tag="LP433_002949"
     tRNA            420..491
                     /locus_tag="LP433_002949"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:453..455,aa:Glu,seq:ttc)
     gene            507..579
                     /locus_tag="LP433_002950"
     tRNA            507..579
                     /locus_tag="LP433_002950"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:540..542,aa:Val,seq:tac)
     gene            589..661
                     /locus_tag="LP433_002951"
     tRNA            589..661
                     /locus_tag="LP433_002951"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:622..624,aa:Asp,seq:gtc)
     gene            697..772
                     /locus_tag="LP433_002952"
     tRNA            697..772
                     /locus_tag="LP433_002952"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:730..732,aa:Phe,seq:gaa)
     gene            774..854
                     /locus_tag="LP433_002953"
     tRNA            774..854
                     /locus_tag="LP433_002953"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:808..810,aa:Tyr,seq:gta)
     gene            861..934
                     /locus_tag="LP433_002954"
     tRNA            861..934
                     /locus_tag="LP433_002954"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:893..895,aa:Trp,seq:cca)
     gene            937..1009
                     /locus_tag="LP433_002955"
     tRNA            937..1009
                     /locus_tag="LP433_002955"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:970..972,aa:His,seq:gtg)
     gene            1021..1092
                     /locus_tag="LP433_002956"
     tRNA            1021..1092
                     /locus_tag="LP433_002956"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1053..1055,aa:Gln,seq:ttg)
     gene            1138..1208
                     /locus_tag="LP433_002957"
     tRNA            1138..1208
                     /locus_tag="LP433_002957"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1170..1172,aa:Cys,seq:gca)
     gene            1229..1313
                     /locus_tag="LP433_002958"
     tRNA            1229..1313
                     /locus_tag="LP433_002958"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1263..1265,aa:Leu,seq:caa)
BASE COUNT          330 a          305 c          354 g          381 t
ORIGIN      
        1 actcggaaaa aaacttatgt gacttcaaat ccagttttga gtgaacaaaa tttactcaat
       61 aaaagataac accacagtgt ggtggcgata gcgagaagga tacacctgta accatgccga
      121 acacagaagt taagcttctt agcgccgatt gtagtgaggg gttgcccctt gtgagagtag
      181 gacgtcgcca cgctgatgtt attccggcat agctcagttg gtagtagcgc atgactgtta
      241 atcatgatgt cgtaggttcg agtcctactg ccggagttct cattttgaga aagagtattg
      301 agcttctttc actctggaga gttgtccgag aggccgaagg agcatgattg gaaatcatgt
      361 agatggtgcc aaactgtctc aagggttcga atcccttact ctccgtagca aatttacctg
      421 gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg gttcgaatcc
      481 cgtacgggtc attttaattg aatgttggag gtttagctca gctgggagag catctgcctt
      541 acaagcagag ggtcagcggt tcgatcccgt taacctccat aatgaactgg ttccgtggtg
      601 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
      661 gtcgttcttg ttattcaatt aataatttta aaatatggcg cggtagctca gttggtagag
      721 caacggattg aagctccgtg tgtcggcagt tcgattctgt cccgcgccac catggaggag
      781 tagcgaagtg gctaaacgcg acggactgta aatccgttcc ttagggttca gtggttcgaa
      841 tccactctcc tccattttat aggggcatag tttaaaggta gaacagcggt ctccaaaacc
      901 gttagtgtgg gttcaattcc tgctgcccct gccatggcga atgtggcgaa gtggttaacg
      961 caccggattg tggctccggc attcgtgggt tcgattccca tcattcgccc tttttattct
     1021 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
     1081 cagctacccc agtttctata atttattctt tattttatag attgataata gtataatggc
     1141 ggtatagcca agtggtaagg cagaggtctg caaaaccttc atcaccggtt caaatccggt
     1201 taccgcctta gtactaataa atcaacttgc cggcgtggcg gaattggcag acgcgctgga
     1261 ctcaaaatcc agtgcccgtt gagggcgtgc cggttcgacc ccggccgccg gtattgacta
     1321 agatgtcttc atcttagttt tttattgaga aattaaataa catcttttat
//
LOCUS       DAFELK010000147         1367 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFELK010000147
VERSION     DAFELK010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.157"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..354
                     /locus_tag="LP433_002959"
     CDS             <1..354
                     /locus_tag="LP433_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2007035.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
     gene            355..903
                     /locus_tag="LP433_002960"
     CDS             355..903
                     /locus_tag="LP433_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007036.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            1163..1367
                     /locus_tag="LP433_002961"
                     /pseudo
     CDS             1163..1367
                     /locus_tag="LP433_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          538 a          173 c          290 g          366 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacagagtag aggaagaaca
      541 aaaaaagttg gcgcaccaat cagaaagttt gataaggttt attccaccaa gcatccttta
      601 aaactgtcga ctttgttaaa tgcgacttcc agagttttag tagaaaagta tgagactaat
      661 atgacaagag atgaattgct tagaaaagct ttagatgagt atattaaaca gaatcttacg
      721 caagaagata agcaagattt gtttaatgac gtggtgaaag aactagactt gttcagagaa
      781 aaatatccaa ttgttccaga attagatgat cgtggagaaa taataagaac taccagtcag
      841 ataaaacaag ataccgaaga ctcactgcgc aaagggtggg gaatgaataa taaagttaga
      901 taataatcaa agaagaacta agtaactacc tttaaacggt agttacttag ttcttctttg
      961 atttgcatga aatagagggg atttattttt ctggttacgt gattaaaaaa tccaaaaaat
     1021 gagcatagga acggttatga ttttagggtg tgttttaatg agatattgtg atttcattaa
     1081 caagtgtatg ataatctgtt gttgagttag taaataagta atagagctaa ctctaaaata
     1141 aaactattag gaggagatgt aggtgaaaaa gtttaaaaag aaaatatatt taggattggt
     1201 tgttggggtg agtatgtttg ggttcatggc tcatactaaa caagtaactg cagatactaa
     1261 ccaaaaagaa aggattatga gccaattaga tgactctcaa ataagtatgt acccaatgag
     1321 ctaattgtca gtttaaaggc tacacaaaga atttcaacag agaaaaa
//
LOCUS       DAFELK010000148         1362 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFELK010000148
VERSION     DAFELK010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.158"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            82..>1362
                     /locus_tag="LP433_002962"
     CDS             82..>1362
                     /locus_tag="LP433_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBL2007037.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          464 a          262 c          257 g          379 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat ta
//
LOCUS       DAFELK010000149         1358 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFELK010000149
VERSION     DAFELK010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.159"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..483
                     /locus_tag="LP433_002963"
     CDS             <1..483
                     /locus_tag="LP433_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2007038.1"
                     /translation="KEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKEQ
                     QVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFSN
                     NQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVIK
                     "
     gene            complement(690..1118)
                     /locus_tag="LP433_002964"
                     /pseudo
     CDS             complement(690..1118)
                     /locus_tag="LP433_002964"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1122..1220)
                     /locus_tag="LP433_002965"
     CDS             complement(1122..1220)
                     /locus_tag="LP433_002965"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2007039.1"
                     /translation="MKERGLSGVKMVISDAHIGLTKAVKEYLLCAS"
BASE COUNT          444 a          254 c          260 g          400 t
ORIGIN      
        1 aaggaagcga tcgatcaaat caagacggct gtcttgtatc ctcataacgg attaccgatt
       61 ttattgatgg gtgtaagcgg ttcaggaaaa acctttttgg cagaaaaaat ttatgaatac
      121 gccaaggaac aacaggtgat agaatcaaat gctccattta tcgcctataa ttgtgctcaa
      181 tactttaatt tctcgattaa caagatcgta gaaaatttaa cgatccttga tgcaatgaag
      241 gttttgagat tggtacaaaa ggccgtcaaa gaactcgaaa aactaatggg gatcgaattt
      301 tcaaacaatc aattgttctt gctttacatg cactgctgct caatgatcga acgtatttta
      361 cgcaaagaaa gtgtagatga acaagcagat atcaaagaat atattcaaaa agagggacat
      421 aattatgaaa tatcaaaata cccggcttac aaaacgaagt ttgaaagtac tgtaataaag
      481 taagatttaa ataagcataa acaaggtaag aaccataggg gctgtgtcaa gtccaaaatc
      541 ttgtgtaaaa aggaaatctc aaagtacgat gttttgcctt gttgagccta gctacggtcc
      601 aatatgctgg taagaagtgt caagagcaaa aagcgaagcg tctcttgata cttctcacca
      661 gtatattata ctattggcgg cttaatgtgc taaatctcgt tacgatcaaa ttcaagatat
      721 tttctaggtg cagaagtcca ttcgtcatcc ttttccatca ataaagcacc gatgatacga
      781 ataacagaat cacaatttgg gaaaattcgg acaacacgtt cacgacggcg tacttcttca
      841 tttagtcttt caagaacatt cgttgttctc aatcgttgac ggatattttc tggtaaaacc
      901 attacttgca tggcatcttc gaagccctca tccaatattt tacaggcagt tgcgactttc
      961 ttgtcttccc catatttatc cataataagt tgtttacgtt ctccagccag ctcgatgctt
     1021 gccgttttga agatggcttt aaagtcttct ttgatatcgc ttgagatttt cttggagaat
     1081 ttgtcggaaa tgttgcgaag gagatgtgct tggcatctct gctagctcgc acaaagaagg
     1141 tattctttca cagcttttgt gagccctata tgcgcatccg agatgaccat ctttactcct
     1201 gaaagaccgc gttctttcaa tccgagagtg taaaatattt tgtgtaaata gaaaaaagga
     1261 agtcccttca gtagaataga gttaccacaa cacattcaca gaaaagagga cttccatatg
     1321 aacgatttta ctacagaaat tctaaagact ctagcgaa
//
LOCUS       DAFELK010000150         1343 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFELK010000150
VERSION     DAFELK010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.160"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(69..1208)
                     /locus_tag="LP433_002966"
     CDS             complement(69..1208)
                     /locus_tag="LP433_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBL2007040.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT          351 a          289 c          249 g          454 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtttatta
       61 aaaaaatctt acgctaagta ggataaaata attccttgat atttttcgat catatccaaa
      121 taattatcga tttcaacata ctcatctact tgatgaggca aagtaacgac accaggccca
      181 aagacgacaa agtcgaagga atggttagct ttcgtaaatt cggctgcatc cgttgttgct
      241 gccgctccaa ctaaaggtaa tggctggctg aattgttgct gaatgcaatg aatcaaagga
      301 gaatctggat cagctttgac aggtattttg ttgtaatcga tcatcaattc caaatgatag
      361 tctgtctctt gattcaattc attgacgatt gattgcagca atgcaatgat tttatcattt
      421 gggtattctg gaatcgatcg aatgttccct tggagctgcg catggcttgg gatgctgttg
      481 acttgattcc cgccactgat caatgtaaca ttatggattg tttttcctag gacaggattc
      541 tcgattgttt cagcgaggtg attcatttca gcatttgctt tcgtaatgaa ttcatttagg
      601 tgattgattg cattataacc ttggtctggc atagagctat gcgcttcttt tccgtgcgag
      661 gtgactgtat agttgattga tcccatgtgc gtatacatca aactgtaatt ggttggctct
      721 ccgatgatca aggcatctaa gtcatctaca tagcctgctt tcgtgagctg ttccccacct
      781 agttcaccca cttcttctcc gacagtggct aataatttga ctgttccgtt aaatggtttt
      841 cctgactctt tcagttcgat catggcaatc accattgctg ccaagccact cttcatatct
      901 gtagcaccac gtccgtacaa acggttccca tggatttctg ctgcaaaggg tgcataggtc
      961 caagacgatt catcaccagc cgccacgaca tccatatgcc cagataggcc taacactttt
     1021 cctgattggc ccttttggta acgagcaatc aaattatctc taccatctct gtaagaaaca
     1081 atctctcctg ttatgtcatg ctttgccaaa agcttattca aataggctgc tacttcacct
     1141 tcgtttccat tcactgattt aattcggata atctcttgta aaatcgcgat tttttcttct
     1201 tttttcatct aatcctctcc cttgccattt ctttttattg tatttgagtg tgctcgaatt
     1261 ttcaaatagg agcaaccaaa gtaaaaatga agaaagagag ccactttatg aaaaatatgc
     1321 tgctacttcc ctcctatttt att
//
LOCUS       DAFELK010000151         1332 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFELK010000151
VERSION     DAFELK010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.161"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..243)
                     /locus_tag="LP433_002967"
     CDS             complement(<1..243)
                     /locus_tag="LP433_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2007041.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQ"
     gene            481..>1332
                     /locus_tag="LP433_002968"
     CDS             481..>1332
                     /locus_tag="LP433_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2007042.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEE"
BASE COUNT          474 a          216 c          227 g          415 t
ORIGIN      
        1 ttgccatacc tcctgaattt gaccatcagg agtcgtaatg aaaatagtat cattttcatc
       61 tactaattct cttaagttta aatattgttt actagatgta aaattcgaag ctgctaatga
      121 cgagtcttcg cttttactat aaaatcctgt tacttgtatt ttatgttcct ggaaatactt
      181 cccgaatgaa caacctacct tgccggctcc aataaaacca acgttcataa ttatcacctc
      241 cataaagaag tgagactaca agtcccattc ttacgatatg agcttaaaaa taaaaattaa
      301 atcaaatata cagtatgttt ttttcaaata tcatccatag ttaatttatc ataatatccc
      361 atattttaaa ataaaagata gcgtaaaata ttttgtgtaa atagaaattt agggtagaaa
      421 aaaaagtcca ttctgtaaaa ttaaagttac cacacagaaa ttttatagga ggactttctc
      481 atgactaaat ttactataga aattatgcaa acactactca ataaagggga tttagatgaa
      541 ttatttcagg atcatttaga gcgagcgatt aattcacttc tacaagcaga gctaactgct
      601 tttttagatt acgaaaaata tgatcgaaat ggattcaatt caggaaattc ccgtaacggg
      661 aattattcac gtacatttaa aacagaatat ggcgagttga atttaactat tcctagagat
      721 cggaatggcg aattttctca acaaacacta ccagcatata agcgaaccaa tgattcatta
      781 gaaacgacca ttatccaatt atttcaaaaa ggcattacta tggctgaaat ctccaaatta
      841 attgaaaaaa tgtatggtca ccactatacg ccacaaacaa tctccaacat gagtaaattg
      901 gtggctgaag atgttttagc ttttaaagaa agaacgttag aagccaatta ttccgttata
      961 tttatggatg cgacgcatat ccctgtgaag cgacagactg tttcgaagga agcagtgtat
     1021 attacgattg gtattcgttt ggatggaacc aaagaagttc ttgggtttac tattgcccca
     1081 actgagtctg cttatatttg gaaagaagtt cttcaagatc ttagaaaacg tgggttagaa
     1141 gaagttttat tagtagtgac agacggatta agctgtattg aagaaagtat ccatagtgtg
     1201 tatccgaatg cccaatttca acaatgttgt gtgcatgtat ctagaaatat cgctcataaa
     1261 gttcgtgttc gaggtcgaaa agaaatttgt gaggatttca aattggttta ccaagcgaat
     1321 tcaaaagaag ag
//
LOCUS       DAFELK010000152         1312 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFELK010000152
VERSION     DAFELK010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.162"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(156..1297)
                     /locus_tag="LP433_002969"
     CDS             complement(join(156..1069,1069..1297))
                     /locus_tag="LP433_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL2007043.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT          323 a          263 c          278 g          448 t
ORIGIN      
        1 gacacgattt gtgagaattt tttcgagatt ccagcgggtg agtatctcat cgtttcgacc
       61 agcggtcaaa ccaaaaccgt ttgaccgctg atcgaagcga tgaagttgaa accctgtgga
      121 aatctcgcca aaaaaatgta agtggtagct aggaactaag cttgcaatgc caactcctcc
      181 atctgatttg gtgttaaata gttgatacta ctatggattc gcttgcgatt gtaaaatcct
      241 tcaatgtatt gaaataacgc taaataagca gcttcaaagt tttcatacgc ttttgatgga
      301 tagacttctt cttttttgag tgaggcgtga aacgattcga taccggcatt atcgtaggga
      361 cagcccttac gactgaagga gtgccgaatg ttcaattcat tcagctttgc ctcataggct
      421 tcgctagtgt actgagaacc caaatctgag tggatgatca agttctcgga gggtgtttgg
      481 tttaagagcg cattgtcaag ggtttcgata accaattctt tcgtcatctg cttgccaaac
      541 ttccaaccga tgactttctt tgtgtggagg tcttgaatag tggagaggta ggtccagcca
      601 tcttttaggg tatgaatata ggtaatatct gtcacccatt tttgattgat cgacgtagtg
      661 gtaaaatctt ggtttaacag gtttttacgt ccttcacttt taactttcgc ttgtttgcca
      721 ggcttgtact tcttgagggt gactgaacgc aagcctaatt ttctcatcag tatttgtact
      781 ttctttaagg acaaggtctc gccacggcca acaagaatct tatgaatttt aggcgcacca
      841 tagataccct tgttttcaaa gtagattcct gaaatcaagc ggtttaagcg tttgttttct
      901 gattggcgct tggaaggttt ctttttcttc cagtcatagt agctggattt cggtgcttcc
      961 aaaacggtac acatttgttt tacgtcatga tcatgaacat ttgattgaat aaattcgaag
     1021 acatcactca tttttacttt tgagcgaata tggttaaagc cttttttagg atagtgtttt
     1081 cctcctgcat gcgggccatt tcctttttca tcgctaggat ttctgcctca gtcatgccgg
     1141 ttgctacatt ctttgtatga agcttcttcc aacgataaat cgtttgtgta gcgataccat
     1201 attgcgctgc cagttcttcg accgattggc cagactggtt taaatctaag atcatcttct
     1261 taaagtcttc atcaaatttt ttcttggctt ttgccatcgt ggacacgtcc tt
//
LOCUS       DAFELK010000153         1302 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFELK010000153
VERSION     DAFELK010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.163"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            52..>1302
                     /locus_tag="LP433_002970"
     CDS             52..>1302
                     /locus_tag="LP433_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2007044.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          403 a          260 c          252 g          387 t
ORIGIN      
        1 cctgaaatcc tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat
       61 actcagctta tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat
      121 tgtttaacta aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg
      181 tacaagccag aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg
      241 gggacgacaa ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag
      301 ctgaagaaac aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct
      361 gttgctgaaa aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta
      421 aaagagaata cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc
      481 tatcgtgtca tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag
      541 gtcttatgct ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc
      601 atgatggacg gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat
      661 ttagaacgct atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt
      721 attgatatgt atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg
      781 atcatcgatc gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg
      841 aaagaaacca cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa
      901 ttgaagcgct attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg
      961 gtttggcgtg ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta
     1021 gctgcttgtc ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta
     1081 aagaaaagag atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca
     1141 gaaacctata caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg
     1201 cttcactaca gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta
     1261 aaacgcaatg cgtacggctt tcgcaacttt tacaatttca aa
//
LOCUS       DAFELK010000154         1257 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFELK010000154
VERSION     DAFELK010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.164"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..626)
                     /locus_tag="LP433_002971"
     CDS             complement(<1..626)
                     /locus_tag="LP433_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL2007045.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGY"
BASE COUNT          360 a          227 c          217 g          453 t
ORIGIN      
        1 tcatatccgc tcggatgatt atgtgatact gcgatttttg ctgaattgtt tagcaaagct
       61 agttgaaaaa tctctcttgg tatcgctact gattgattaa ttccaccttt gaaaacttcg
      121 ctataagcaa tgacctcatt ctttgtattc agacacatca ctagcaaaga ttcactagca
      181 ttgtttccaa ttaagttagt agcaaagttt gctagaccaa ccgagcttgt gactctataa
      241 aaacttctat cttcactgat atatttttgt tcgattttca agacattctt aatcaatcct
      301 tcaccttcat tctcggtctt gttttcaact tcaatagatt caagactgct atttcccata
      361 tcagaaccca acaaagcatt tctgaaatcc aatacctttt caaagttatc agtcataacc
      421 atttcatagg tgctattcca ttcattcaaa tatttctctt tgatgagaat gaacgctctc
      481 ggtttacttc tgccaattct gatattttgt gtatcgtgaa aaatatagtt atcaagtaaa
      541 gtaccatcgt acttttcata gttcccactg atatttgtta acttgtttac catttcttga
      601 ttaacttcta aaattctatc tctcatgttg aacgcttctt tctgtttttg atttttggtt
      661 tttcaaaatt cttttttgtt tggattgttt tagagggagg tggttttttc ttcatcgcta
      721 tttggttttg cattttatgt ttcttccttt cgttcattta tttatctttt tcgcctgtct
      781 tgccttgtcg ggagtgatta gaatgcgttc ttatctgccg gattaataca agtgtttaag
      841 taaattattt tcgtaacgct tgcgtttaga aaaaaattta cgccacttgt attaatccaa
      901 agatgagata agctctaaac acttctgaca aggtatgaca ggcgaaaaag ataatgggcg
      961 taaggaatta taaatggcaa aaccaaataa agagcgatga atttcaatgc tttcaggcgt
     1021 agcttgaaag cctaaaagtc ttgaagaatg aaagactttt taccttcaaa gcagacctag
     1081 taatcttaaa taggcgatgg ctatttaaga ttacggtgtt gacccactaa ataaacagaa
     1141 atggaaccga tcaagcaaaa tcggactagg cgatggctag gacggtttgc ggtggcttta
     1201 ggaaacgttc atggtgagat gagcatatct agcaatgtcg ggctaagcta tgcttag
//
LOCUS       DAFELK010000155         1246 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFELK010000155
VERSION     DAFELK010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.165"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            200..742
                     /locus_tag="LP433_002972"
     CDS             200..742
                     /locus_tag="LP433_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007046.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="LP433_002973"
     CDS             898..>1246
                     /locus_tag="LP433_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBL2007047.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAFELK010000156         1188 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFELK010000156
VERSION     DAFELK010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.166"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            141..398
                     /locus_tag="LP433_002974"
     CDS             141..398
                     /locus_tag="LP433_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007048.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="LP433_002975"
     CDS             complement(630..1061)
                     /locus_tag="LP433_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBL2007049.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DAFELK010000157         1156 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFELK010000157
VERSION     DAFELK010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.167"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..243
                     /locus_tag="LP433_002976"
     CDS             <1..243
                     /locus_tag="LP433_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2007050.1"
                     /translation="VRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKIENLHT
                     HIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(347..547)
                     /locus_tag="LP433_002977"
     CDS             complement(347..547)
                     /locus_tag="LP433_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2007051.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            943..1092
                     /locus_tag="LP433_002978"
     CDS             943..1092
                     /locus_tag="LP433_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007052.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
BASE COUNT          384 a          210 c          178 g          384 t
ORIGIN      
        1 gtaagaacga tgcccaattc cgttccaaaa gaactgcatt ctataaaaaa agcttttata
       61 aactatgaat ccggcattcg tttagccctc gaattgcctt attcaaatgc caaaatagaa
      121 aatctgcata cccacatcaa agcattgaaa cgagtcgctt atggctttcg aagctttcgg
      181 aaaatgaaga ccagaatttt cttactaaat aatctgatta cctatgaatc aaaaaacatc
      241 taaagtagaa aaggaattct accttagatg ttcttatctc actctatcag tcctatttga
      301 caaagagccc ttttctttcg aaaagacggt taaaagtcaa tttttattaa gctttaacaa
      361 tgtttgttgc ttgagggcca cgttgaccat cttcaacatc gtaagacact gcttggcctt
      421 cttctaaagt tttgaagccg tcaccttgga tagctgaaaa atgtgcaaat acatcatttc
      481 catcttcacc agtgataaag ccaaaacctt tgtctgcgtt gaaccatttt actgtaccgt
      541 tattcataaa taaattcctc ctgatacgta tcaatgtacg ttttttcgtt gcaataaata
      601 tttgataggc aaaaggagtt ttatctatgt agatatatcg ctcaaattac gtttcaaaat
      661 agattactca tttaatatat catgcttttt ctaataacac aaggataatg caatgaaata
      721 taaaattcat tgtcttctat tgtcttcgaa tcgaagaaaa agttgaataa ccgcgattga
      781 ttcacttttt gttttcttgt ttatttgctt ttatctgcaa cttttgactt taaaatttct
      841 taactatgaa aacctttcaa ttggtggtat acttataaat ggaatttcgt tatcaacgcg
      901 ttcgttgcct ttcagcaagt atttaaagaa aggagaatgg ctatgacatt ctataacaaa
      961 gatatacaat atcgagtaac cttggataca gatttgaatc tatttgtcgt ttttgacaaa
     1021 gaaaatacca atcatgtagc gacaggtgtt acgatcgaac aagcagtgca agaattaaaa
     1081 aaatctgcat aaggagtgga aaccctcata tggacgattc tcgttcttct ctttaaacgc
     1141 atctactggt agataa
//
LOCUS       DAFELK010000158         1149 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFELK010000158
VERSION     DAFELK010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.169"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            64..>1149
                     /locus_tag="LP433_002979"
     CDS             64..>1149
                     /locus_tag="LP433_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HBL2007053.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVRTLNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRG
                     VHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKDRKEICDDFKAV
                     YQASSKEEANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGIRRSIYSTNLIE
                     SFNKQIKKYSRRKEQFQNEESLERFLVS"
BASE COUNT          381 a          233 c          228 g          307 t
ORIGIN      
        1 aaaggaagtc ccttctgtag aatagagtta ccacaacaca ttcacagaaa agaggacttc
       61 catatgaacg attttactac agaaattcta aagactctag cgaacaaagg cgatttgaat
      121 gaattattcc gtgtccattt ggaaaaagct gtcaatacgc ttctcaaaac ggagttaacg
      181 gctttcctcg attacgaaaa gtacgatcgc attggtttta acacgggtaa ttctcgtaac
      241 ggctcctatg accgtacggt caagaccgag tacggggaac ttcatctcca gattccgcgc
      301 gaccgcaacg gcgagttcaa gcaacagact gttcctgctt atagacggac gaatgatacc
      361 ttagaggaga ccgtcattca cctcttccga aaaggtatta ccatgtcgga aatcgcagac
      421 ttgattgaga aaatgtatgg gcatcactac acgccccaaa ccatgtccaa catgactaaa
      481 gtgctgactg aagaagtaaa tgcatttaaa gttagaactc taaatgataa gtatgtcgct
      541 attttcatgg atgctactta tattccttta aaacggcaaa ccgtctccaa agaagcaatc
      601 tatattgcca ttggtatacg agaagacggc actaaagaag tactaagtta tgcgattgcc
      661 ccgactgaat cgacctacgt ttggaatgag ttgttacagg acatttactc cagaggggtt
      721 catgatgtct tactgtttat taccgatggc ttaaaaggca tgaaagatac gattcaccag
      781 atttatccta aagctaaata ccaacattgc tgtgttcacg tttcccgtaa tattgctcat
      841 aaagtacgtg tcaaagatcg aaaagaaatc tgtgatgatt ttaaggctgt ttatcaagct
      901 agctcaaagg aagaggcaaa taccttttta gggagtatga ttgagaagtg gcagaaaact
      961 tatcctaaag tgacgcagtc actgataaaa aatcaagatt tattgacttt ttatgagttt
     1021 ccgcctggta tccgccgaag catttactca actaatttaa tcgaatcttt caataaacaa
     1081 atcaagaaat acagccgcag aaaagagcag tttcaaaatg aagaatcact agagcgtttc
     1141 ctagtatcc
//
LOCUS       DAFELK010000159         1146 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFELK010000159
VERSION     DAFELK010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.170"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            58..414
                     /locus_tag="LP433_002980"
     CDS             58..414
                     /locus_tag="LP433_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2007054.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
     gene            404..670
                     /locus_tag="LP433_002981"
     CDS             404..670
                     /locus_tag="LP433_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2007055.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            829..>1146
                     /locus_tag="LP433_002982"
     CDS             829..>1146
                     /locus_tag="LP433_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBL2007056.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKN"
BASE COUNT          469 a          143 c          221 g          313 t
ORIGIN      
        1 attcgaattt ttatgttata tactataata taaaatcaat atatgatata attgggtatg
       61 gaaaaaatat cttttgaaac atttaaaaga cctaatggtc atgatgaatt tttagaatgg
      121 ttggaaacat taccaaaaaa agatagtgcg aagcttttac gtacaataga agaaacagaa
      181 aagaatggga tgctagtagc tcaacggttg aaatgggtga aaaaattaga cactaatttg
      241 tacgaattaa gaagtaaggt aggatcaaac atccaaagag ctatctattt ccatgtggtc
      301 aatggaaggt atgtcattac ccatggattt actaaaaaaa cggagaaaac accaataagt
      361 gaacttaaac atgcaaaaga acttagagag gagtggttca caaatgatga ttaaaaaatt
      421 gattgaagaa aagcaaaaag acaaagattt tgcagaagca tatgaccgtg aaggaagaaa
      481 actcgaaact gcggttgctc tttatcatgc acgggaggaa gcaggcctaa ctcaagcgga
      541 gcttgcacaa aaagcacata caactcaatc tactattgct cgaattgaga gaggggataa
      601 cgtatctttc gataaacttg atgatatcgc tagggcatta ggcaaaaagc tggtagtaga
      661 atttgcttaa aagcgagttg aaaatatacc tgtaataggc tcctaactaa tcaattagtt
      721 tagtgggcct ttttgtacta aatagataaa agttgtccta tagtgtaaaa gtcaataaat
      781 tttatacaaa aattacttta aagagacata aagagaaagg tacaataaat gaaaaccata
      841 aatctaataa aagtatttat agcatcacca ggtgatatag cagcaaagag gaatgaagta
      901 gaagaaacca tatatagatg gaatatagaa aatacagata atacaaaagt aattttgatg
      961 ccaattcgat gggaaacgaa tgcgattcct acttatataa ataatagctc tgggcaaagt
     1021 gttattaata aacaaattgt agaaaatagt gatatattat tagcgatttt tggccataag
     1081 ttgggttctc cagttgataa ttatagatcg ggaactatag cagaaattga ttacttttat
     1141 aaaaat
//
LOCUS       DAFELK010000160         1112 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFELK010000160
VERSION     DAFELK010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.172"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            154..417
                     /locus_tag="LP433_002983"
     CDS             154..417
                     /locus_tag="LP433_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2007057.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="LP433_002984"
     CDS             417..689
                     /locus_tag="LP433_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL2007058.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            766..1095
                     /locus_tag="LP433_002985"
     CDS             766..1095
                     /locus_tag="LP433_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2007059.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT          423 a          141 c          220 g          328 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga
      841 gtcgaagttg aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa
      901 aaagaatttt atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat
      961 aaagatgaga ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga
     1021 gatattgctg aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca
     1081 gaaattggct tatgaaatcg ttccttcaaa ac
//
LOCUS       DAFELK010000161         1092 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFELK010000161
VERSION     DAFELK010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.173"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(281..353)
                     /locus_tag="LP433_002986"
     tRNA            complement(281..353)
                     /locus_tag="LP433_002986"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(318..320),aa:Ala,seq:tgc)
     gene            complement(430..>1092)
                     /locus_tag="LP433_002987"
     rRNA            complement(430..>1092)
                     /locus_tag="LP433_002987"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          279 a          285 c          241 g          287 t
ORIGIN      
        1 cggttgggtt ttgatccttc ttctagcgat agaagttaga tcaagaaaat aagcaattga
       61 acttattaaa aaactctatc cagctcacaa atcagcctgt gcggcaaaaa gatcgatcgt
      121 ctcataaaat caaagatttt atagccgtcc gcctattttg ctttaggcta aacaatttgt
      181 tcagctttca aattcaacgc ggtgttctcg gtttgtatta cttacattta cttcaaatat
      241 ccagttttca atgaacaaat ttaacaacta atgttgttaa tggagcctag cgggatcgaa
      301 ccgctgacct cctgcgtgca aagcaggcgc tctcccagct gagctaaggc cccgttttaa
      361 attgagagta aacctctcaa aactgaacaa agtaaaaaca aattgtgtag tctccgtaat
      421 attccttaga aaggaggtga tccagccgca ccttccgata cggctacctt gttacgactt
      481 caccccaatc atctatccca ccttaggcgg ctggctccaa aaggttacct caccgacttc
      541 gggtgttaca aactctcgtg gtgtgacggg cggtgtgtac aaggcccggg aacgtattca
      601 ccgcggcgtg ctgatccgcg attactagcg attccggctt catgcaggcg agttgcagcc
      661 tgcaatccga actgagagaa gctttaagag attagcttag cctcgcgact tcgcaactcg
      721 ttgtacttcc cattgtagca cgtgtgtagc ccaggtcata aggggcatga tgatttgacg
      781 tcatccccac cttcctccgg tttgtcaccg gcagtcttgc tagagtgccc aactgaatga
      841 tggcaactaa caataagggt tgcgctcgtt gcgggactta acccaacatc tcacgacacg
      901 agctgacgac aaccatgcac cacctgtcac tttgcccccg aaggggaagc tctatctcta
      961 gagtggtcaa aggatgtcaa gacctggtaa ggttcttcgc gttgcttcga attaaaccac
     1021 atgctccacc gcttgtgcgg gcccccgtca attcctttga gtttcaacct tgcggtcgta
     1081 ctccccaggc gg
//
LOCUS       DAFELK010000162         1090 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFELK010000162
VERSION     DAFELK010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.174"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            4..978
                     /gene="bsh"
                     /locus_tag="LP433_002988"
     CDS             4..978
                     /gene="bsh"
                     /locus_tag="LP433_002988"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBL2007060.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          382 a          136 c          187 g          385 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagttact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaaactaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgatgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aacatttttt cttgatgtga tatccttgtc ttttttgtaa
     1081 tgtttttaac
//
LOCUS       DAFELK010000163         1073 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFELK010000163
VERSION     DAFELK010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.175"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            263..1057
                     /locus_tag="LP433_002989"
                     /note="aph(3')-IIIa"
     CDS             263..1057
                     /locus_tag="LP433_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL2007061.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          340 a          182 c          268 g          283 t
ORIGIN      
        1 caaagcataa aaacttgcat ggactaatgc ttgaaaccca ggacaataac cttatagctt
       61 gtaaattcta tcataattgt ggtttcaaaa tcggctccgt cgatactatg ttatacgcca
      121 actttgaaaa caactttgaa aaagctgttt tctggtattt aaggttttag aatgcaagga
      181 acagtgaatt ggagttcgtc ttgttataat tagcttcttg gggtatcttt aaatactgta
      241 gaaaagagga aggaaataat aaatggctaa aatgagaata tcaccggaat tgaaaaaact
      301 gatcgaaaaa taccgctgcg taaaagatac ggaaggaatg tctcctgcta aggtatataa
      361 gctggtggga gaaaatgaaa acctatattt aaaaatgacg gacagccggt ataaagggac
      421 cacctatgat gtggaacggg aaaaggacat gatgctatgg ctggaaggaa agctgcctgt
      481 tccaaaggtc ctgcactttg aacggcatga tggctggagc aatctgctca tgagtgaggc
      541 cgatggcgtc ctttgctcgg aagagtatga agatgaacaa agccctgaaa agattatcga
      601 gctgtatgcg gagtgcatca ggctctttca ctccatcgac atatcggatt gtccctatac
      661 gaatagctta gacagccgct tagccgaatt ggattactta ctgaataacg atctggccga
      721 tgtggattgc gaaaactggg aagaagacac tccatttaaa gatccgcgcg agctgtatga
      781 ttttttaaag acggaaaagc ccgaagagga acttgtcttt tcccacggcg acctgggaga
      841 cagcaacatc tttgtgaaag atggcaaagt aagtggcttt attgatcttg ggagaagcgg
      901 cagggcggac aagtggtatg acattgcctt ctgcgtccgg tcgatcaggg aggatatcgg
      961 ggaagaacag tatgtcgagc tattttttga cttactgggg atcaagcctg attgggagaa
     1021 aataaaatat tatattttac tggatgaatt gttttagtac ctagatttag atg
//
LOCUS       DAFELK010000164         1065 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFELK010000164
VERSION     DAFELK010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.176"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            39..>1065
                     /locus_tag="LP433_002990"
     CDS             39..>1065
                     /locus_tag="LP433_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2007062.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAF"
BASE COUNT          334 a          213 c          207 g          311 t
ORIGIN      
        1 aattgaatca ccacaacaca atcaaaggag cgttctgtat gcctgatctt catcatatca
       61 aactactact tggaatcaaa gataaaaaca ttttcatcac aaatgtggaa tcgaagagca
      121 ttaagaatat caagagtctt gttgtttctg cgacgttaag taaagaaatt cgtcgctgtc
      181 ctttgtgtaa acagatgaat catgaaggca tgatcgttaa gaacggaaag aaaaaatcgc
      241 tcattcaact taataaatgt gcgaaccaac tgacttatct tgctttagcg aaacaacgct
      301 accactgtcg tggctgccac acctatttta cggcgaatac ctacattgtc gatagaaact
      361 gctttatcgc taaacaagtg cgctataaaa ttttagaaga gctaactgaa aaacaagcaa
      421 tgacgacaat tgctaagcat tgcggcgttt cttggtcgac cgtttctcgg acactcgctt
      481 ctctgatccc catgacaaaa gtaaaaagaa attggttacc gcgttgttta ttaatggatg
      541 aatttcgttc actgaaaaat caagtcggtc cctactcctt ttcttgtatg gatggcgata
      601 ctggaaaatt actggatatt cttccttcac ggaagaaaaa ggctctcgtt tcttatttta
      661 tgcaatttga acgacgcgca cgattgaagg taaaggtcat cgtgacggac atgaatgttt
      721 cttatgcctc tctgataaag gaatgttttc caaaggcaaa actcgttgtg gatcgttttc
      781 acattgtcaa acatctcatt cgtaaatttg aggatattcg cgtacgaatc atgaaaagct
      841 ttgatcgaaa cgatccaaca caagccaaat attatcgaca attaaaggcg ttgtctcggc
      901 ttctgatcaa acgacaggac aagcttgttt atgacaaatg gaccaaatgg cgcaattttg
      961 gttgggcgta tctcaccgaa agtgaagtgg tggatcgtct gctttcgatc tctgacgaat
     1021 tacgaatcgc ctatttttac tatcaagaaa ttcttcaagc gtttc
//
LOCUS       DAFELK010000165         1064 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFELK010000165
VERSION     DAFELK010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.177"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(210..581)
                     /locus_tag="LP433_002991"
     CDS             complement(210..581)
                     /locus_tag="LP433_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007063.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIFIVESELIAKVSLGLLIPI"
     gene            complement(632..>1064)
                     /locus_tag="LP433_002992"
     CDS             complement(632..>1064)
                     /locus_tag="LP433_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007064.1"
                     /translation="KELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEM
                     IAYLKHKNILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYL
                     NHGLYYRVMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
BASE COUNT          351 a          176 c          106 g          431 t
ORIGIN      
        1 aattctaatc cttctttttt aaacagtaac tttctatcta tacatctcga gaaataattg
       61 tatttatatt ctttaagctc aatatctgtt ttattatctt tatcccatgc aattcttttt
      121 aacatattac cacttaatcc ttcatgtaat aactgctttt ttatttgaat acgtgtatac
      181 aagttattaa agtaaattgc tgaacctatt tatatcggaa ttaacagtcc aagagagacc
      241 ttggctatta actcagattc aactatgaaa atataaaaaa accaaataaa tgaagggatt
      301 aaccaagcaa aaatttctaa tatcacatta aatcttttca tttttccaaa actactaaga
      361 cttgatacta attcaatcaa aagcttatcg ctacttgctg attcatcata tttagttcct
      421 agattatcta aacttagcat ataagaaatt ttttcctgat ctgttagttt tgaaaatgaa
      481 ctttctttta aactttggat tatacaatca gcactaaata tttcgtttaa taaagcagtt
      541 ttcttttcta attccttaga agataaagtt agttctctca tagtgactta cctactttcc
      601 aaattttgtg tcctatttat cacttctctc tttatataag tgataaaaga tcgtaaatac
      661 gtttaattgt taagttcata ttcacatgat tatccaaata aaatatctta tctttattag
      721 aaatttcact cataacacga taatatagac catgattcaa gtaatctgta tatagaaaaa
      781 tcgcatcaca cgtattcaaa tttttaagta tctttccatt attttcgctt acatcaaaca
      841 ttttaatatt tggtaatagt tcagttaatt tattttgaaa atttacatgt cctcccacta
      901 aaagaatgtt tttatgtttt agataagcta tcatttcaga cagtgaaggc tcttcagttt
      961 taccatttaa tgattgtcta tgttcttgct cctgcaattg ctttaatact ttattttcaa
     1021 acctcagctg ttcaagttct tttctgattc cttttaattc ttta
//
LOCUS       DAFELK010000166         1063 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFELK010000166
VERSION     DAFELK010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.178"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(36..992)
                     /locus_tag="LP433_002993"
     CDS             complement(36..992)
                     /locus_tag="LP433_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007065.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          178 c          160 g          379 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca act
//
LOCUS       DAFELK010000167         1053 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFELK010000167
VERSION     DAFELK010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.179"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(<1..828)
                     /locus_tag="LP433_002994"
                     /note="aph(2'')-Ia"
     CDS             complement(<1..828)
                     /locus_tag="LP433_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBL2007066.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEF
                     "
BASE COUNT          351 a          175 c           81 g          446 t
ORIGIN      
        1 aaattcctgt ttaatatttt taattccata aacaatagtt tcaataggat aatattcttc
       61 aactatatct tgatattctt ttgctttctc aatatctata tttccataca ttcttaatat
      121 atcttctcca aaatttgttc ctatttcttc ttcactatct tcaagtaagt atataaaatc
      181 acaatattca tctataattc cagaatctcc aaaatcaatt attccagtta atctattatt
      241 gccatctaac aatagatgat tacaactaaa atcattatgg cataaacact ttttaccctc
      301 aaaaactgtt gttgcattta gtctttccat aaaactttct atataatctt tttctatatc
      361 agttaaatca ttataaatag tttcacgcaa caatatatac tcttctaata cattttgttt
      421 attatcaata gtacattcac taatatctgt ataatctaaa ccgtgcattt gtcttaaaaa
      481 actggcaata tctcgtttta acaaattttg ttcttcttct gacatagtag aataaatttc
      541 tggtgttaaa aaagttcctt taatttcttt ataacctagt atagataatt catcactaat
      601 atacgaatat tcaatattag gaatttttac attagtttct aaatttgtat ttaaaaaatt
      661 atatattgct ttttcttttg cataaccttt tttcttatta gtactaaatt ttgttttaaa
      721 aatgtattca ttattaacta aatatgccac actatcataa ccactaccga ttatttcaat
      781 actatctact ttgaaattat caaagtaatg ctcaattaaa tatttcattg ccttaacatt
      841 tgtggcatta tcatcatatc tatattccat taaataacaa tcttcttttt tgccctcgtg
      901 taattcatgt tctggcaaat cttcaataat tctaaaacca gatttttggt atgcccttat
      961 tgctcttgga ttatttttat gagggtctaa aataactgca ttagcatttc tttctttttt
     1021 caaaaattca aaaatcaatt taatatatct tgt
//
LOCUS       DAFELK010000168          985 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFELK010000168
VERSION     DAFELK010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.180"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            48..>985
                     /locus_tag="LP433_002995"
     CDS             48..>985
                     /locus_tag="LP433_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2007067.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTK"
BASE COUNT          355 a          179 c          187 g          264 t
ORIGIN      
        1 tacactcaaa atagttccga cgaaagaatt ataaggagtg agtacaaatg acctataacc
       61 atcttacacc aactgaactc gtaatgatag aagcttattt caatcaatca caacctgttt
      121 caaaagtagc caatctgtta caacgttctc gacaaactat ttataaggtc tatcgttttc
      181 ttaaatctgg tggaagcgca atgagctact ataaacaata taagaaaaac aaacgtaact
      241 gcggaagaca tccgattgtt ttacctgatg agcaacagga atacattcaa aaaaaggttg
      301 ttcaagggtg ggctcctgat gtccttattg gtcgagcaga gtttcctatt gcttgttcgg
      361 tacgcacact gtatcgaatg tttaaagata aaacctttga cactcacgat ttaccaatga
      421 agggaaaaag aaaaccaaac ggtcataaag aaaaaagagg aaaacaaggg tttcgccggt
      481 caatccgaga cagaaagaca gactataccc agtttgatca tgaatttggt cacctggaag
      541 gtgacactat cgtgggtgga aaacataaaa gcgcggtcat cacattagtt gaacggctat
      601 ctaaagtcat cattaccttg aaacccgaag gcagacaggc taaagacatt gaaaataggc
      661 tgaatcaatg gtttcgttgt gtcccaaaaa acttatttaa atccatcaca tttgattgtg
      721 gaaaagaatt ctcaaattgg aaaaagatta gtaataccaa cgatatttca atttattttg
      781 cggatccagg aacaccttct caacgaggat tgaatgaaca ttcaaatggc ttattacgta
      841 aagatggttt gtataaagct atggatttta atggtgtatc tgaaaccttt atccaatcgg
      901 tggcatcgaa acgaaatcat attcctagaa aatcattaca ctatcggaca ccaatggaag
      961 tatttttgag ttacgtcaca aaaga
//
LOCUS       DAFELK010000169          911 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFELK010000169
VERSION     DAFELK010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.181"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(1..>911)
                     /locus_tag="LP433_002996"
     rRNA            complement(1..>911)
                     /locus_tag="LP433_002996"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          201 a          286 c          197 g          227 t
ORIGIN      
        1 taagtcctcg atcgattagt atcagtccgc tccatacatc actgtacttc cactcctgac
       61 ctatctacct gatcatctct cagggatctt actttcttaa agaaatggga aatctcatct
      121 tgaggtgggc ttcacactta gatgctttca gcgtttatcc cttccctaca tagctaccca
      181 gcaatgccct tggcagaaca actggtacac cagcggtaag tccatcccgg tcctctcgta
      241 ctaaggacag ctcctctcaa atttccaacg cccgcgacgg atagggaccg aactgtctca
      301 cgacgttctg aacccagctc gcgtgccgct ttaatgggcg aacagcccaa cccttgggac
      361 cgactacagc cccaggatgc gacgagccga catcgaggtg ccaaacctcc ccgtcgatgt
      421 ggactcttgg gggagataag cctgttatcc ccagggtagc ttttatccgt tgagcgatgg
      481 cccttccatg cggaaccacc ggatcactaa gcccgacttt cgtccctgct cgacttgttg
      541 gtctcgcagt caagctccct tctgccttta cactcttcga atgatttcca accattctga
      601 gggaaccttt gggcgcctcc gttacctttt aggaggcgac cgccccagtc aaactgccca
      661 tctgacactg tctcccacca cgattagtgg tgcgggttag agtggccata acgcaggggt
      721 agtatcccac cagcgcctcc atcgaaacta gcgttccgat ttctacggct cctacctatc
      781 ctgtacatgc ggtacagaca ctcaatatca aactacagta aagctccatg gggtctttcc
      841 gtcctgtcgc gggtaacctg catcttcaca ggtactaaaa tttcaccgag tctctcgttg
      901 agacagtgcc c
//
LOCUS       DAFELK010000170          890 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFELK010000170
VERSION     DAFELK010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.182"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..888
                     /locus_tag="LP433_002997"
     CDS             <1..888
                     /locus_tag="LP433_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBL2007068.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DAFELK010000171          831 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFELK010000171
VERSION     DAFELK010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..831
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.183"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            8..>831
                     /locus_tag="LP433_002998"
     CDS             8..>831
                     /locus_tag="LP433_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2007069.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDF"
BASE COUNT          286 a          146 c          158 g          241 t
ORIGIN      
        1 agtacaaatg acctataccc atcttacaac ggatgaactt gtaataatag agtcttattt
       61 caaaatgaat caatctgttg ctaaaactgc ccattgcttg aatcgttcaa gacaaacgat
      121 ccataaagta tatctgttct tcaagcaagg aaaatcagcc ttagaatatt atcaacagta
      181 taagaaaaac aaatcaaact gtggtagacg tccgcttgtt ttacccgagg aacaatcaga
      241 atatattcaa agaaaggttg ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc
      301 gtttcctatt agttgttctg ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttga
      361 ttcttctgac ttaccgatga aaggcaagcg taaaccgaat ggacatcaag aaagacgtgg
      421 aaaacaaact ttccgccgct ctattcatga acgtgaaaag gattatagcc aattctcaaa
      481 tgagtttggt caccttgaag gtgacactat cgtaggtctg aaacataaaa gtgctgtaat
      541 taccttagtt gaacgattat caaaagttat catcacattg aaaccgtgtg gtagacaagc
      601 gattgatatt gaaaaaaaat taaatcaatg gtttgaatct gtaccgaaaa acctattcaa
      661 atccatcact tttgattgtg gaaaggaatt ttcaaattgg aaacagatca gtaatgtcaa
      721 tgatattgcc atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa
      781 ttctaacgga ttgttacgta gagatggttt attgaaatct atggatttca a
//
LOCUS       DAFELK010000172          803 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFELK010000172
VERSION     DAFELK010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.184"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            195..770
                     /locus_tag="LP433_002999"
     CDS             195..770
                     /locus_tag="LP433_002999"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBL2007070.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
BASE COUNT          295 a           93 c          171 g          244 t
ORIGIN      
        1 ttccttcagt ttttcagatg atataccact caaaaaacaa tatgagagat gttcaggaat
       61 accatctcta atggcttata aattggtttt agggatagta gatgttatag acatatcaag
      121 gaataaacga gcagctgcat aaaagcagat ggaattaagg aataattgaa ttgtaaaaga
      181 agggaataaa tttaatggca caattatttt acagatatgg aacaatgaat agtggaaaga
      241 gtattgagct actgaaagtg gctcataatt atgaagaaca agggaagaga gttatcataa
      301 tgacaagcgc aatagatact cgatcaggat ttggaaaagt tgagagtcgt ataggtgttt
      361 cgaaaccagc tattgcaatt acttctgaaa tggatgtgta cggagaatta gtggagatta
      421 ttgatcagta cggaaaagtt gattgtattt tggtcgatga gtctcaattt ttaagtagag
      481 agaatattat tgatctatca cttatcgtaa tgaatgagga agtaccagta atttgctatg
      541 gattgaagaa tgattttcaa aataatctct tcaagggatc cgaagcatta ttgacatttg
      601 ctgataaaat tgaggaaatt aaaactattt gccatttttg caataaaaag gctgtaatga
      661 atgctcgtat tgttgatggt attccagttt attcaggtga acagattgta gtaggaggta
      721 atgaagatta cctttcggta tgtcgcaacc actactacaa cgaagattga aataaaaaac
      781 gtgtaatcaa ataattgatt aca
//
LOCUS       DAFELK010000173          788 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFELK010000173
VERSION     DAFELK010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.185"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            1..788
                     /locus_tag="LP433_003000"
                     /pseudo
     CDS             1..788
                     /locus_tag="LP433_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612146.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          301 a          133 c          147 g          207 t
ORIGIN      
        1 agaaaaagat aatcttacgc ctgaacaaaa agaattgtta gaactacgta aaagaaacca
       61 gcaattagaa atggaaaatg atattttaaa gcaagcagcg ctgatattcg gacgaagaga
      121 caagtaatcg atgcgaataa gcatctttac cctatatcag cgatgtgcag aatattaggt
      181 ctatcacgtc agtcctatta ttatcaatca aaaccaaaga aagacgaatc agaacttgaa
      241 gaagtagtcg ctgaagaatt tatccgcagc cgaaaggcct acggctcaag aaaaataaaa
      301 aaagccttat caaaacgagg cattcagatc agccgacgaa aaattagtag aatcatgaaa
      361 aatagaggat taaaatcgag ctatactgtt gcttatttta aagtacatca ttctacttgc
      421 aatgaagcca aaacgacaaa cgtattgaat cgtaaattct taagagacaa cccattagaa
      481 gcgatcgtaa cagacttgac ttatgtacga gtcgggaaaa aatggaatta tgtctgtttc
      541 attttggatc tgttcaatcg agaaattctc ggctattctt gtggagaaca taaagatgcc
      601 gttctagtaa aaaaagcatt tagccgtatc aaacaacctc tgacagaggt tgagattttt
      661 catactgatc gtggaaaaga gtttgataac caagctattg atgaattatt aacaactttt
      721 gacatcaatc gatcattgag tcataaaggc tgtccttttg ataatgccgt agctgaatca
      781 acttataa
//
LOCUS       DAFELK010000174          695 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFELK010000174
VERSION     DAFELK010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.186"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(53..628)
                     /locus_tag="LP433_003001"
     CDS             complement(53..628)
                     /locus_tag="LP433_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2007071.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          124 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaac
//
LOCUS       DAFELK010000175          691 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFELK010000175
VERSION     DAFELK010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.187"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..>691
                     /locus_tag="LP433_003002"
     rRNA            <1..>691
                     /locus_tag="LP433_003002"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          216 a          141 c          197 g          137 t
ORIGIN      
        1 ctatgatcca gagatttccg aatgggggaa cccaacatct ttaataggat gttacgattg
       61 tgtgaataca tagcacattc gaggtagacg cagagaactg aaacatctaa gtacctgcag
      121 gaagagaaag aaaattcgat tccctgagta gcggcgagcg aaacgggaaa agcccaaacc
      181 agcaagcttg cttgttgggg ttgtaggact ccaatatggt agttctttca gatagtcgaa
      241 tgacttggaa aagtcagtca aagagggtaa aaaccccgta gacgaaatgt ggaagacacc
      301 taggaggatc ctgagtacgg cggaacacga gaaattccgt cggaatccgg gaggaccatc
      361 tcccaaggct aaatactccc tagtgaccga tagtgaacca gtaccgtgag ggaaaggtga
      421 aaagcacccc ggaaggggag tgaaatagaa cctgaaaccg tgtgcctaca acaagtcaaa
      481 gcccgttaat gggtgatggc gtgccttttg tagaatgaac cggcgagtta cgattgcatg
      541 cgaggttaag ttgaagagac ggagccgcag cgaaagcgag tctgaatagg gcgtttgagt
      601 atgtagtcgt agacccgaaa ccatgtgatc tacccatgtc caggttgaag gtgcggtaaa
      661 acgcactgga ggaccgaacc cacgtacgtt g
//
LOCUS       DAFELK010000176          688 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFELK010000176
VERSION     DAFELK010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.188"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..549
                     /locus_tag="LP433_003003"
     CDS             <1..549
                     /locus_tag="LP433_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2007072.1"
                     /translation="IDNNKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQ
                     KRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSW
                     SKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHD
                     RDINASINILTEGLRLHSMGLA"
BASE COUNT          256 a          110 c          131 g          191 t
ORIGIN      
        1 attgataata ataaattcac gtccaaaatg gaaaagaaac taaagcgtga acaacgcaaa
       61 ttgtctaggc gtgctttatt ggctaaaaat aaaggtacca atctatttga agctaaaaat
      121 tatcaaaaac aaaaacgcaa agtagctaga ttgcatgaaa aagtaatgaa tcaacgtact
      181 gattttctga ataagttgag tacagaaatg atcaaaaatc acgatattat ctgtattgaa
      241 gacttaaaca caaaaggtat gttgcgaaat cataaattag ctaaaagtat ttctgatgtt
      301 tcttggtcaa agtttgtgac taaattacaa tacaaggctg actggtatgg acgaaaaatc
      361 atcaaagtag ataaatggtt tccgtctagt cagatttgtt cagagtgcgg acataaagat
      421 ggcaagaaat ctcttgaaat tcgagaatgg acttgtcctg tttgtcatac tcatcatgat
      481 cgtgatatca atgctagtat caatattctg accgaaggtc taagactaca ttctatggga
      541 ttggcttaga tccaatcatc aagaaccgta ggaactacgg ggatagcttg gtaaataaga
      601 gacaccgctg ttagtaaaga aatacgctat caagtatgct ctattcccaa gaagctccca
      661 cttcaagcgt taagaaccgt caggttta
//
LOCUS       DAFELK010000177          625 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFELK010000177
VERSION     DAFELK010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.189"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..>625
                     /locus_tag="LP433_003004"
     CDS             <1..>625
                     /locus_tag="LP433_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2007073.1"
                     /translation="MTKSFTEEVTSFKERELHDRYAAIYMDATYIPLKRKTVAKEAIH
                     IAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERGVKNVLLFITDGLKGMAGAVQ
                     RFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMVYQASSKKAALEARGAFAEKW
                     KTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIESFNKQIKKYS"
BASE COUNT          183 a          134 c          140 g          168 t
ORIGIN      
        1 atgactaaat catttacgga agaagtcact tcatttaagg aacgtgagct tcatgaccgt
       61 tatgccgcta tttatatgga cgcaacctat atccctttaa agcggaaaac cgtcgccaag
      121 gaagccattc atatcgcagt tggcattcgc ccggacggtt caaaggaagt gttgagctat
      181 gcgattgcac caactgaatc tatcacgatt tgggaagaga ttttaataga cctccaggaa
      241 cgtggcgtga aaaacgtcct ccttttcatc acggatggct taaaggggat ggcaggggcc
      301 gtgcagcggt tctaccccaa agcccgtttt caacattgct gtgtgcacgt ttcccgtaat
      361 atcagtcaca aagtgcgtgt cgatgatcgt aaggaagtct gtgatgattt taaaatggtg
      421 tatcaagcgt catctaaaaa ggcggcattg gaagcacgtg gtgcttttgc ggaaaaatgg
      481 aaaaccagtt atccaaaaat ggtggaatcg atcctttcga acgattacct gctcactttc
      541 tatgattttc cattagccat acgcaagact atttactcta cgaacttgat tgaatccttt
      601 aataagcaaa tcaagaaata cagcc
//
LOCUS       DAFELK010000178          603 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFELK010000178
VERSION     DAFELK010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.190"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..322
                     /locus_tag="LP433_003005"
     CDS             <1..322
                     /locus_tag="LP433_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2007074.1"
                     /translation="EALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIY
                     STNLIEGFNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTL
                     ESMI"
BASE COUNT          215 a          106 c           75 g          207 t
ORIGIN      
        1 agaggcattg gatcacatcg actttatgac taggaaatgg aaaaagcagt atccaagagt
       61 cgtcaattta ctcttgaatc ctgccctatt aaccttttat aatttccctc acgccatcag
      121 acgaacaatt tattcgacga acctgattga aggctttaat aagcagctaa aacgatatac
      181 tcgaagaaaa gaacaattcc ctaatgaaga atctctagag agattcttca tttctcaatt
      241 taatcaatat aaccaaaaat ttttaggtag aattcacaag ggatttaaag aaattcagga
      301 tacattagag tcgatgattt aactgtaatt aacagaatgg attttccatt tacatataat
      361 tcttgacgct accataatct aaataaccat catattcatc tactacttat ataattgagt
      421 tttattaaac tttttaagtt tctattctat caaatattta aacaatctct gcatccgaaa
      481 agactacctc gtatagtttt actaacaata tttttattag cgtgttcaaa tcctgatttc
      541 ttgtatcaat tattttctgt tcactttcaa taagaaaaaa gtctttactt ccatggataa
      601 taa
//
LOCUS       DAFELK010000179          558 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFELK010000179
VERSION     DAFELK010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.191"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..>558
                     /locus_tag="LP433_003006"
     CDS             <1..>558
                     /locus_tag="LP433_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL2007075.1"
                     /translation="KGKGRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVRE
                     IRALEKNIKELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKL
                     AKYAGLSWKVNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYK
                     EVPKHQHKRALVLTARKFTRLVDTLL"
BASE COUNT          208 a          105 c          102 g          143 t
ORIGIN      
        1 aaaggaaaag gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt
       61 accatgagtt accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt
      121 ctcgtacgag aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa
      181 caagtaattg ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa
      241 gtctatgctg ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca
      301 aaattggcaa aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg
      361 caaaatacac ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct
      421 gccaactctg taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag
      481 gaggttccaa agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt
      541 ctggtggata cgctacta
//
LOCUS       DAFELK010000180          547 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFELK010000180
VERSION     DAFELK010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..547
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.192"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
BASE COUNT          217 a           69 c           92 g          169 t
ORIGIN      
        1 ttagcatcaa gcgtgttatg tgttcttttt ttgactttat ttttctacta tagagacatg
       61 ctcaatttat gtggtcaaaa ttcaaatcta ggtggggata tagagttaaa aatatattga
      121 catgtgtaaa tttacatgat atattcattt ctgttgtttt aagtagcaaa gcaataaaat
      181 agtattttaa aaaacatata aaatagttgt tgacatgtta gaaatgacat gataagataa
      241 ctgagttgtt aaaaaagaac cacttgtgaa gcttgattct atcgaaaaaa acttcaaaaa
      301 agttcttgac aaataacaaa tgataagtta tgataaatga gttgctgtaa gatttcgaaa
      361 aacgaaatca aaaaaacttt taaaaaagag ttgacaatta cttgtctctc tgatatgata
      421 taaaagttgc tacggcagcc aaaaacgaat cggggaacac tcctgatgaa gtagaccttt
      481 gaaaactgaa caaagtaaga caaaccaaat gtgtagggcg tcttgattca attcaagaca
      541 acaaaca
//
LOCUS       DAFELK010000181          528 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFELK010000181
VERSION     DAFELK010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.193"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(5..90)
                     /locus_tag="LP433_003007"
     tRNA            complement(5..90)
                     /locus_tag="LP433_003007"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="LP433_003008"
     tRNA            complement(107..178)
                     /locus_tag="LP433_003008"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="LP433_003009"
     tRNA            complement(190..262)
                     /locus_tag="LP433_003009"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="LP433_003010"
     tRNA            complement(280..361)
                     /locus_tag="LP433_003010"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="LP433_003011"
     tRNA            complement(369..441)
                     /locus_tag="LP433_003011"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="LP433_003012"
     tRNA            complement(445..517)
                     /locus_tag="LP433_003012"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAFELK010000182          521 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFELK010000182
VERSION     DAFELK010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.195"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..>521
                     /locus_tag="LP433_003013"
     CDS             <1..>521
                     /locus_tag="LP433_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HBL2007076.1"
                     /translation="ENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDKL
                     PVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNK
                     EPDAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTD
                     NRSDADKYEPTVEG"
BASE COUNT          211 a           84 c          120 g          106 t
ORIGIN      
        1 gaaaatccag gagaaaacat tcctgcaggc taccacaaag taaccttcac cgcaggagaa
       61 ggaacaagta ttgaaagtgg aacaacagtc tttgcagtga aagacggcgt aagcttacca
      121 gaagataaac ttccagtgtt gaaagcaaaa gatggttata cagatgcgaa atggccagag
      181 gaagcaactc aaccaattac agcagatgat acagaatttg tatcaagtgc aacaaaactg
      241 gatgataaat ctgacgctga caaatataat cctgaaggtc aaaaagtgac tacagaattg
      301 aataaggaac cagacgcatt tgagggaatt aagaacaaag aagatttacc aaaagatact
      361 aagtatactt ggaaagaaaa agtagatgtt agcgcagctg gaaataaaaa agggactgtt
      421 gtagtgacat atccagatgg atcatctgat gaagttgaag tagatgttac agtgacagac
      481 aatcgttctg acgccgataa atatgagcca acagtagaag g
//
LOCUS       DAFELK010000183          517 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFELK010000183
VERSION     DAFELK010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.196"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            57..>517
                     /locus_tag="LP433_003014"
     CDS             57..>517
                     /locus_tag="LP433_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2007077.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
BASE COUNT          191 a           72 c          105 g          149 t
ORIGIN      
        1 ataaatatgt tataatagta tcaaatgaat attgctaaaa gaaaagaggt aggaacgtgg
       61 tagcgaagaa atatgtaatc ggtaatttta aaggtggcgt aggtaaaagt acgtgcgcgc
      121 aaatgttagg gtttgaatca gcagttaatg aaggaaaaag aaccttgata attgacttgg
      181 atatgcaagg aaatacttct gatgtgatga acttaacgca tatgaacttc actaacgaag
      241 aaggaggcgg agaaggtgaa ccgattgttt acgaaaatac tgtgactgac gtgttgataa
      301 acaatcttcc acctaaagag gctgtctata aagtaatcaa taacctctat atacttccag
      361 cagacatgtc ctttgaaatg tatgatgatt ggatcaaaga ccaatataat gattcattat
      421 cccaattcaa atatatgaaa gaaaagctag aaccattatt tgatgagttt gacgtcatct
      481 atttagatgt cccaccttct atttctgtat atagtaa
//
LOCUS       DAFELK010000184          513 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFELK010000184
VERSION     DAFELK010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.denovo.198"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            12..263
                     /locus_tag="LP433_003015"
     CDS             12..263
                     /locus_tag="LP433_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007078.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            279..>513
                     /locus_tag="LP433_003016"
     CDS             279..>513
                     /locus_tag="LP433_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007079.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFF"
BASE COUNT          204 a           77 c          105 g          127 t
ORIGIN      
        1 aagaaacgct gatgaaaaca caacacaaat tattgactgt aaaagaagtc gttcaaattt
       61 tggtggacaa agaagtcatt tctgaaaaag tagcagaagc tttacttatt ccgcggtact
      121 ggacgataga aaccccttta gtagaggatg caccgactat gctatttgaa gacctagtga
      181 agattgcagg atatgaactg cattatcaag aaaacatgga aacttatgaa aacgaatatt
      241 ggttaaccaa attagagaac taaaaaggag aaaaaaatat ggctcaaaat tactatgacg
      301 aatttgtcaa attacctttg gataaaatgg cacaaaaaat ggaggatatg acattcctat
      361 acaatgagac acgtgttcca aaaaaacatt ataaggaaag attgtcggta gctgtggaag
      421 aaatgattga atcgggtgtc gaaatgaatc tcattgcgac ctactatcga acgcttgaag
      481 aactgaaaaa gcaaaatgga caatggtttt tcc
//
LOCUS       DAFELK010000185        56204 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.012, whole genome shotgun sequence.
ACCESSION   DAFELK010000185
VERSION     DAFELK010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.012"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            216..701
                     /locus_tag="LP433_003017"
     CDS             216..701
                     /locus_tag="LP433_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBL2007080.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            694..1377
                     /locus_tag="LP433_003018"
     CDS             694..1377
                     /locus_tag="LP433_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBL2007081.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            1503..4148
                     /gene="polA"
                     /locus_tag="LP433_003019"
     CDS             1503..4148
                     /gene="polA"
                     /locus_tag="LP433_003019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBL2007082.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            4193..5029
                     /gene="mutM"
                     /locus_tag="LP433_003020"
     CDS             4193..5029
                     /gene="mutM"
                     /locus_tag="LP433_003020"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBL2007083.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            4993..5622
                     /locus_tag="LP433_003021"
     CDS             4993..5622
                     /locus_tag="LP433_003021"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBL2007084.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            5674..6006
                     /locus_tag="LP433_003022"
     CDS             5674..6006
                     /locus_tag="LP433_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL2007085.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            6318..6809
                     /gene="nrdR"
                     /locus_tag="LP433_003023"
     CDS             6318..6809
                     /gene="nrdR"
                     /locus_tag="LP433_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBL2007086.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            6832..8205
                     /locus_tag="LP433_003024"
     CDS             6832..8205
                     /locus_tag="LP433_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL2007087.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            8205..9131
                     /gene="dnaI"
                     /locus_tag="LP433_003025"
     CDS             8205..9131
                     /gene="dnaI"
                     /locus_tag="LP433_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBL2007088.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            9260..9700
                     /locus_tag="LP433_003026"
     CDS             9260..9700
                     /locus_tag="LP433_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL2007089.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            9844..10545
                     /locus_tag="LP433_003027"
     CDS             9844..10545
                     /locus_tag="LP433_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBL2007090.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            10542..11663
                     /locus_tag="LP433_003028"
     CDS             10542..11663
                     /locus_tag="LP433_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBL2007091.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            11678..12910
                     /gene="pepT"
                     /locus_tag="LP433_003029"
     CDS             11678..12910
                     /gene="pepT"
                     /locus_tag="LP433_003029"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBL2007092.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            13042..13950
                     /locus_tag="LP433_003030"
     CDS             13042..13950
                     /locus_tag="LP433_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBL2007093.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            13985..14257
                     /locus_tag="LP433_003031"
     CDS             13985..14257
                     /locus_tag="LP433_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBL2007094.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            14268..15314
                     /locus_tag="LP433_003032"
     CDS             14268..15314
                     /locus_tag="LP433_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBL2007095.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            15565..18174
                     /gene="clpB"
                     /locus_tag="LP433_003033"
     CDS             15565..18174
                     /gene="clpB"
                     /locus_tag="LP433_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBL2007096.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(18325..19011)
                     /locus_tag="LP433_003034"
     CDS             complement(18325..19011)
                     /locus_tag="LP433_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007097.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(18989..19483)
                     /locus_tag="LP433_003035"
     CDS             complement(18989..19483)
                     /locus_tag="LP433_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL2007098.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(19503..20723)
                     /locus_tag="LP433_003036"
     CDS             complement(19503..20723)
                     /locus_tag="LP433_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2007099.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            20870..22705
                     /gene="lepA"
                     /locus_tag="LP433_003037"
     CDS             20870..22705
                     /gene="lepA"
                     /locus_tag="LP433_003037"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBL2007100.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            22901..23473
                     /locus_tag="LP433_003038"
                     /pseudo
     CDS             22901..23473
                     /locus_tag="LP433_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            23886..24359
                     /gene="dfrF"
                     /locus_tag="LP433_003039"
     CDS             23886..24359
                     /gene="dfrF"
                     /locus_tag="LP433_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL2007101.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            24466..24996
                     /locus_tag="LP433_003040"
     CDS             24466..24996
                     /locus_tag="LP433_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2007102.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            25542..25784
                     /locus_tag="LP433_003041"
     CDS             25542..25784
                     /locus_tag="LP433_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBL2007103.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITSHKVK"
     gene            25781..26251
                     /locus_tag="LP433_003042"
     CDS             25781..26251
                     /locus_tag="LP433_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL2007104.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            26379..27593
                     /locus_tag="LP433_003043"
     CDS             26379..27593
                     /locus_tag="LP433_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL2007105.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECISYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            28582..28791
                     /locus_tag="LP433_003044"
     CDS             28582..28791
                     /locus_tag="LP433_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBL2007106.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            28903..30516
                     /locus_tag="LP433_003045"
     CDS             28903..30516
                     /locus_tag="LP433_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2007107.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGKVE"
     gene            30551..30898
                     /locus_tag="LP433_003046"
                     /pseudo
     CDS             30551..30898
                     /locus_tag="LP433_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            31894..32145
                     /locus_tag="LP433_003047"
     CDS             31894..32145
                     /locus_tag="LP433_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007108.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            32228..32500
                     /locus_tag="LP433_003048"
     CDS             32228..32500
                     /locus_tag="LP433_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007109.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            32590..32829
                     /locus_tag="LP433_003049"
     CDS             32590..32829
                     /locus_tag="LP433_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007110.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            32976..37259
                     /locus_tag="LP433_003050"
     CDS             32976..37259
                     /locus_tag="LP433_003050"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBL2007111.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            37358..37723
                     /locus_tag="LP433_003051"
     CDS             37358..37723
                     /locus_tag="LP433_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007112.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            37725..38177
                     /locus_tag="LP433_003052"
     CDS             37725..38177
                     /locus_tag="LP433_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007113.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            38791..40101
                     /locus_tag="LP433_003053"
     CDS             38791..40101
                     /locus_tag="LP433_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBL2007114.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            40124..40435
                     /locus_tag="LP433_003054"
     CDS             40124..40435
                     /locus_tag="LP433_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007115.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            40796..42052
                     /locus_tag="LP433_003055"
     CDS             40796..42052
                     /locus_tag="LP433_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL2007116.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            42049..42594
                     /locus_tag="LP433_003056"
     CDS             42049..42594
                     /locus_tag="LP433_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007117.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            42595..43095
                     /locus_tag="LP433_003057"
     CDS             42595..43095
                     /locus_tag="LP433_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007118.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            43176..43732
                     /locus_tag="LP433_003058"
                     /pseudo
     CDS             43176..43732
                     /locus_tag="LP433_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            43752..44096
                     /locus_tag="LP433_003059"
     CDS             43752..44096
                     /locus_tag="LP433_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007119.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            44115..45026
                     /locus_tag="LP433_003060"
     CDS             44115..45026
                     /locus_tag="LP433_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2007120.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            45105..46097
                     /locus_tag="LP433_003061"
     CDS             45105..46097
                     /locus_tag="LP433_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2007121.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            46094..46312
                     /locus_tag="LP433_003062"
     CDS             46094..46312
                     /locus_tag="LP433_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007122.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            46325..46735
                     /locus_tag="LP433_003063"
     CDS             46325..46735
                     /locus_tag="LP433_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007123.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            46787..49315
                     /locus_tag="LP433_003064"
     CDS             46787..49315
                     /locus_tag="LP433_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2007124.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            49331..51541
                     /locus_tag="LP433_003065"
     CDS             49331..51541
                     /locus_tag="LP433_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007125.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            51549..52640
                     /locus_tag="LP433_003066"
     CDS             51549..52640
                     /locus_tag="LP433_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL2007126.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            52661..53203
                     /locus_tag="LP433_003067"
     CDS             52661..53203
                     /locus_tag="LP433_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007127.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            53398..53655
                     /locus_tag="LP433_003068"
     CDS             53398..53655
                     /locus_tag="LP433_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007128.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            53669..54001
                     /locus_tag="LP433_003069"
     CDS             53669..54001
                     /locus_tag="LP433_003069"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007129.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            54046..54594
                     /locus_tag="LP433_003070"
     CDS             54046..54594
                     /locus_tag="LP433_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL2007130.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            54601..55053
                     /locus_tag="LP433_003071"
     CDS             54601..55053
                     /locus_tag="LP433_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007131.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            55150..55485
                     /locus_tag="LP433_003072"
                     /pseudo
     CDS             55150..55485
                     /locus_tag="LP433_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        19322 a         8867 c        11983 g        16032 t
ORIGIN      
        1 tgttcaaaag cttgcatctg cggtaataag cccaatcaaa tcaaaaacat gagaagctgt
       61 tttttcttgg ctgttcttat tatttgatgc aggacagctt tttcacgacc tctgtaaact
      121 ataggaatct gttaaatcaa gggagcagaa cttgcctttt acgctacttt tggtacaata
      181 atgtatgatt aaaaataaac tggagggttt ctatcttgaa cataggtaag ccgagaaaac
      241 taggaaaaac aataaatgaa atcgaggaag gcgactcgtt atccttaaca gaatctattg
      301 aagataacca gcttttgctg tatttgggat tgacgaatga tgcaaatcct ttgtatatcc
      361 aacatgactt tgcacaaaaa acagaatatc aacagccaat cgttccatca gtgatgctga
      421 tggggatcat cacaagtgca atttcaaagc atcttcctgg accaggatca catgttgtca
      481 atttttctgt caattttatt gaaccggttt tccattatga aacactgact tttcagtttg
      541 aggtcataaa agtagataag atgaaggatg tggtgacgat ttctgtagaa gcggagaata
      601 cgaacgaaga tcgtgtgttg gatgctgtcg ttatggtcca accgccacaa gttcctgaat
      661 tggaaatagc aatcgaaagt gaaggtgaat tgaatgaata atccaagtac atcaatgtca
      721 ggtatcaatc gtttttatgc aaaagtttat ggatttttag gtatgggact tgcccttagt
      781 gcagtcactt cttacttggc tctttgggta tttcctttgc aattagcaac ttttatcaat
      841 aattttccac taggctttgt gggtctgtgg atcgttgaac tgattttagt aatggttcta
      901 ggcgtaaaag cacaaaagaa tccgagctta gcaatcggtg gatttattgc ctactctctt
      961 ttgaatggca taatattagc ggttactctt gcatactacg atattggaac agtaacgcaa
     1021 gctttcttga cagctacttt gatgttcatg gggatgtctg ttgtcggagt aacaacaaaa
     1081 agagatctta gcggggttgg aagagcagga caggcagctt taatcggagt gatcattgca
     1141 ctagtcttga acatcttcat tttgagaagt agcgtagttg agctgttcat ctccctactg
     1201 ttagtcgtca tctttgcagg gattacagct tatgataacc aaagcatccg taatatctat
     1261 gtccagacaa acggaacagc acatagtgga attgctgtat tcatggcatt gaagctgtat
     1321 ttggacttta tcaacttgtt cttggcgttt ctgagaatct ttggacggaa caactaaaaa
     1381 agaaaaaaat tcatcagttg gggctatacc gaattatttg gtatggtccc gctttttctt
     1441 ttcgcattcc gcaggattct ttgttagaat gaataagaac tttacagtaa ggagttaaga
     1501 agatgacaaa aaataaatta ttactcgttg atgggaacag tgtggctttt cgcgcattct
     1561 ttgcgcttca caattctctt gaacgtttca aaaatagaaa cggtcttcat acaaatgcaa
     1621 tctatgcatt caatacgatg tttgaaaatg ttatgcaaaa agagcaaccg actcatgttc
     1681 tggttgcgtt cgatgcagga aaaacgactt ttcggacaga aatgtatgcg gagtacaaag
     1741 gtggaagatc caaaacacct ggcgaattca aagaacaaat gccatatata cgtgatttgt
     1801 tgacaggact aggggtacag tattacgaat tgcccaatta tgaagcagat gatattatcg
     1861 gtactttggc agaaaaagta gacaaagatc aatttgatgt cgtcgtgctt tcaggtgatc
     1921 gggatttgac tcaattagct agtaaagaag taaaagtgga tatcactgta aaaggtgtca
     1981 gcgatatcga aagctataca ccagaacatg tagcggaaaa atatgatggg ttgacgccaa
     2041 aacagattat tgacatgaag ggactagccg gagatgcctc tgacaatatc cccggtgtga
     2101 ctaaaatcgg tgaaaaaaca gctatcaagc tattgaaaca atatggctca gtcgaaggaa
     2161 tttatgaaca tatcgatgaa atgaagcaaa gcaaaatgaa agaaaatctg ataaatgaca
     2221 aagagcaggc tttcttatcg aaaaaattgg cgaccatcaa tacttcagcg cctgtggatg
     2281 tctctatcga ctcattgaag tatgaaggga aaaatctcga taaactcgtt ccgttttata
     2341 aagaaatgga tttcaatcag ttcctttcta aattgaatat cgtagaagaa gaagtaaaaa
     2401 tggatgatat tttgtttgaa gtcgttcatg aattcaaaga ggaaatgttt actacggata
     2461 tggcgttgta cgtggaaatg atgggcgaca attatcatac agaggaaatc gtcggagtag
     2521 cgtgggggac agaaaagaaa atttatgtca cgaacgatct atctgtattc gaaaaccgag
     2581 cgttccattc ttggatcact gatccgactc ggctgaaaaa agtatatgat gcgaaacgaa
     2641 cttatgttgc tttaaaccgc tatactggaa aaacgaaagg aatcgatttt gatgtcttgc
     2701 taggtgcata ccttctcgat acgaatgaaa aaagcacaga tatcgaagga atagctgctc
     2761 attacggata caacgatatc caatcagatg aagctgtata cggcaaaggg gcgaaaaaag
     2821 gtttaccaga agaagaggaa ctcttttttg ctcatttagc gcgaaaagta gctgcaatca
     2881 atgcgttgac accaaaattg agccaagaac tggcagaaaa aaaccaagaa gatcttttcc
     2941 ggaaaatgga actgccattg tctatcattt tggcagagat ggaaataagc gggatcaaag
     3001 tagatgcgac tcgcttacaa gaaatgaagg gcgagttctc tgctcgctta agagagatcg
     3061 aacaaaaaat ctacgaagaa gccggcgaag aattcaattt gaattcacca aagcaattag
     3121 gagtgatctt atttgaaaaa atgggattac ccgttatcaa aaaaacaaaa actggatatt
     3181 ccacagccgt agatgtactg gaacagcttc gtgaacaagc accaatcgta gaggatatcc
     3241 tcacctatcg tcaaattgca aaaattcaat ctacctatgt cgagggactg ctgaaagtga
     3301 tccaatcaga tggaaaagtg catacccgtt atgtccagac attgacccaa acaggacgat
     3361 taagctctgt tgatcctaat ttgcagaaca tcccgattcg attagatgaa gggagaaaga
     3421 tacgtcaggc atttgttcct agagaaaaag actggctgat ttattcttct gactattcac
     3481 aaatcgagtt acgcgtactt gcgcatatct caaatgatga acatttgaaa gctgccttcc
     3541 tagaaggtca agatatccat gccagcacag cgatgcgtgt atttggaatc gaaaaggcag
     3601 aggatgtcac accaaatatg cgtaggcagg caaaagcagt gaattttggt atcgtgtatg
     3661 gcatctctga ttacggactt tcacaaaatc taggaatcag ccgaaaagca gcacagcaat
     3721 acatcgatac gtactttgaa aaatacccag gtgtcaaaga atatatggaa agaatcgtac
     3781 gcgaagcaaa agaccaaggc tacgtcgaaa cgctgtatca ccgccgtcga tatctgccag
     3841 acatcaattc aagaaattac aatatccgtt cttttgcgga acgaacagct atcaatacac
     3901 caatccaagg aagtgctgct gatattttga aaatcgcgat gatcgaattg gataaacgat
     3961 taaaagaaac aggtcttcaa gctacgatgc tgttacaagt tcatgatgaa cttgtcttcg
     4021 aggtaccgga aaaagaactt gaatcattag ataaattggt gaaggaagtt atggaacaag
     4081 ctgtttctct tcatgtacca ctgatcactg acagcagttg gggaaaaacg tggtacgaag
     4141 caaaataaac attgtttaag acagagcaat ataatgaagg tgaaaagaaa aaatgccaga
     4201 attaccagaa gtagaaaccg ttcgtaaagg attggaacgg ttagtagtag gaaaaacgat
     4261 tcaaaaagtt caggtcttgt ggcccaagat catcgagcaa ccagagacac ccatctttga
     4321 ggcttctctt gttggcgaaa ccatccaatc cattggacgt agagggaagt ttttaatttt
     4381 tcatctcgat cattgtgaac tgatctcaca cttgcgaatg gaaggaaaat atcaatttac
     4441 gaaagaaaat acaccaatcg ataaacatac gcatgtactt ttcttttttg aggatggaag
     4501 ccaacttcgc tacaacgatg tacgaaaatt tggtcgtatg acaatcgtcg aaaaaggagc
     4561 aagtgcaact taccgaggaa tcatgaaatt gggacctgag cctttgccag atagcttctt
     4621 attagcagat ttcgcaaatg gactgaaaaa gtcccacaaa gcaatcaagc cattgctgct
     4681 agaccaacgt ctagtgactg gtctaggtaa tatttatgta gatgaagcat tatgggaagc
     4741 gaagatccat ccagaacaac cggcgaacac actgcgcccc aaagaggtag aacaattacg
     4801 tctatcgatc attgatgttt tggatcgtgc aatagaagcc ggaggtacca cgattcgcag
     4861 ttatttgaat gcattaggag aatcaggcgg atttcaagta gcactgcatg tctatcagca
     4921 aactggcaaa ccatgtatac gttgtggaac gccgatcgtg aaaacaaaag tggcacaaag
     4981 ggggacgcac tattgtccga attgtcaaag gctaaaaatc gcaaagtagg atttgtttta
     5041 ggtttgacgg gtggaatagc taccggtaaa agtacggcag ccaaagtctt tcagtctcat
     5101 ggatttcctt tgatcgatgg cgatgtgatt gccagagaaa ctgttgagcc tggaacgctt
     5161 gctctgagga aaattgtatc agtgtttggc caagaggtat tgcagcctga tgggcaacta
     5221 gatcgaggga aacttgggat gattgttttt ccatcaaagg aaaaacggca aaaacttgat
     5281 cagctattag atccgtttat ccgaaaagcg ataaaagatc aaatcgcctc tctaagttcc
     5341 aatcatcctt tagtaattgt agatatccca ttgctctacg aaggtcatta tgaccactat
     5401 atggatgcag tagctgtcgt ttatactacg ccagaaactc agcttcagcg tttgatgaaa
     5461 cgtaatcaac tgacgctaga acaagcgcag cagagaatta gtagtcaact tccaatcgaa
     5521 gaaaaaaagc agcgtgcgga tattttgttc gacaacaatg gaacaaaaga aatacttgtg
     5581 ggacaaatcg aaaattggct ttttgctaat cgctttcttt gagtatctgt gtcaattttg
     5641 ctatcctgag tatatagaaa gtgagggata gcgatgggat cattaaaaaa tcaaaaggat
     5701 aaagtcgtag gtaacgcaaa agaaaaaatc ggcgagatgc tcaataaaga aaatctaatc
     5761 gatgaaggtc gtacgcaatc agaaacagca gaagaaaaag aaaagcagta ccaagcaaga
     5821 atcgatgaaa tagaagacca gcaggcagaa gaagaagcga agcggcaaga tttgactcaa
     5881 gaacgaaaaa atccgacacc tgatcgtagt aaaacaccgc tcccagaaag tgaccacatt
     5941 cccgatgagc aaaaaatcga ggaacagcga atgaaacact atacaggaat cgaagagaag
     6001 ttataaaata gtaaaaaatc gagatgtgac ttgaagcaga tgagaaggtg ttcatctgct
     6061 tcaagttttt tgtgctagat gactaaatca gcttttgtgt aagttatttc tcagtaatca
     6121 aggtgatcag tattggaaaa ttgaaattta gtaaggacag gggacacaat tacgcatgaa
     6181 agtagaaaaa attgttctta tatccgtgtt ttttgggtag gacagtcgcg tttgtgattt
     6241 gtttcgtgtt ataatacaac tagttgtaaa gaaagacaca tcctttatat aaaatgcgat
     6301 gcaagaggtg agacaaaatg agatgtccca gatgtcaaca taataattca cgagtaatcg
     6361 acagccgtca agcagatgat ggacgtgcga tccgtcgccg tcgcgaatgt gagaattgtt
     6421 cgttccgatt cactacattt gaacgaattg aagctgctcc gttattagta atcaagaaaa
     6481 acggggaacg cgaagagttc aatcgcgata aaattttaag aggactcatc cgttcagcag
     6541 aaaaaagacc tgtagctatg gaacaaatgg aacaaatcgt caaccatgtc gaaaaccgcg
     6601 tacgcagtct cggagaaaac gaagtatcga cgaatctaat tggtgaatat gtgatggaag
     6661 atttagttga tttagacgaa atcgcttata ttcgttttgc aagtgtttat cgccagttca
     6721 aagatatgtc tgttttctta aaagagttgc aagatatcgt ggataaagca aaagaaaata
     6781 ataaagagaa taataaagaa aacaattaag aaacaaaaag gaggcatttc cttggaaaat
     6841 gcttggaaag agcttcaacc aaaaaatatt taccaaggaa gaaaagcggc tccgctgaga
     6901 gaagacagca agaacgcctt gctgtatctt tatcagccac taatcggcgg agaagccttg
     6961 agtatctatt tcaccctgtt atcagaaatc tctcaagaat ctggcaaagg tcctgaaggg
     7021 atgcatgcag atctgcttag tagtctaggc tgcggtatcc cgcaatttta tgatgcaaga
     7081 aaaaagctag aaggaatcgg cttactggat gtttatttta aagaagatag tgatctggga
     7141 cctcgtttta tttatgagct gttagaacca ctcattccta aagcattttt caaagactct
     7201 gttctggctt ttcttcttct ggaaaaagtt ggtgaacgac gattccagaa gcttacccaa
     7261 ttctttgaac ctaaaaggca tacagcagag ggatatcaaa aaatcacaaa aaaattttta
     7321 gatgtttatc gcttcaatga agcagtgtac gctgctaatc aagaaaacat cgaatcgctg
     7381 aataaatctt ttgaagaatc tgaatcagta gcattacttg aagcagattc gacattcgat
     7441 tggcagtttt tgaatgattg gctggcaaaa aaacatattg caagtcttga tgatccaatc
     7501 atcaaacaag tcgacatgta tcatcagctt tacggtttcg atgaattgac acttggcgaa
     7561 ctgatcagtc aatcttatga ctttagtgaa caaaaagtat ctgaaaaaga actgcaaaaa
     7621 gccattttgg caatgcagag acgtccggtg aagcaaacaa aagaaacagt tgcggtttct
     7681 gaaaacagta atgaaccctc gtcaaacgaa catttgacaa acgcagcgct tcagctgata
     7741 aaagaagcac agagcattcc accgatgaaa tatctggaag caatcaagtc agaaaaaggc
     7801 ggatatgttt ctaaacaaga aaactggtta ctgcaagatc ttgtttctca atcaggtctt
     7861 tccagtagcg tgatcaatgt tttgctgaat tatgtactag tgatcaagaa taatgctagc
     7921 ttaaatgcca gttatgtaaa tacagtggca aatgaatggg cacaaaagaa aatcgccaca
     7981 gcagaagaag cgatccagca cattcggcaa ataagtaatc aagcaaaaca atcaaaacaa
     8041 aagaagcaaa caaattatca aactggcaag cgaaatgttc gacgggaaaa gcttcctgat
     8101 tgggtcaacc agccaaaaga tgaaaaacag atcagcagcg agaaaaaagc agagattgac
     8161 cgccgtttta aagaatacct ggcaaaaaag gagggtgata tctagtggaa gacgtaggca
     8221 aagaattgaa gaggatcatc agcaaacgca attatcaaga aaagtatgct gaaatgatcg
     8281 ctgaagtctt aaatgatgcg gatgttcaag cttttctaag cgcacaccaa gaagaattga
     8341 cacaagcgga tattgaaaaa agttacgcta aattgtatga attcgtgcaa gaaaagcgta
     8401 aatatcaaaa aaacgatcca acgatgatcg ctcccggcta tgagccgaag ctgacgttga
     8461 attttcatta tgtggatgtc acttatgtac caacggaagc attgttagca cggcaaagac
     8521 aagaagaaat cagaagccga gtaaaagcaa tggatatgcc aaaagatatt caatcggctt
     8581 cttttgaaaa ctttgaacgt acagatggac gaggatatgc gagcttagaa gccctagatt
     8641 ttgtagagaa atatactgct gatccaaaag ggtatcataa aggactgtat ctagtaggaa
     8701 gttttggtat tggaaaaaca tatttattag gagcaacagc gagagaatta gcgattgctg
     8761 gattcaccac gacgctagtc cattttccga catttgccgt tgagatgaaa caggcaatcg
     8821 gaaaagatca agtggcagaa aagttagatg cagtgaaacg ttcacctatt ttgatgatcg
     8881 atgacattgg tgcagatgcg atgagtagtt ggatacgaga cgaagtattc ggtgttatcc
     8941 ttcaatatcg gatgcaggaa cagttaccaa ccttcttctc atcgaatttt acaatggatg
     9001 aattggaaca gcatttgtcc gtcactcaac gtggagatga agagccgcta aaagcgaaac
     9061 ggataatgga acgcatacgt tatttgacaa aagaaatcga aatgactggt cgcaaccgac
     9121 gcaatggttg aacagttgac aagtccaact gacatttgac ctagtagtaa aagcaggtca
     9181 gcgaatcatt atatggacag aaatgaccgg agacaatcac cgcaacaagt aatgcagaaa
     9241 cttaaacgga ggatttttta tgagggctat tttttctagt atatctgtag ttggtctatt
     9301 ttttctttta gcaggctgcg gtagcgcaga tagcaacaca ggttctgttg attcgattga
     9361 tgcgggtcaa acagtaaaaa caagcagtac gaaaacggag agacaaagca tatttgtcgg
     9421 aacgattgaa agtatcactc aagtagaagc agaagaagaa acgcttcagt tgaaactcgt
     9481 cgatgtcatg gccaaagaag atccagcgaa tatgggaacg tcattcagca atgacggagt
     9541 gatcttaaat gctactgctg aaaaaataag cgtggacata aatgaattga aaatcggtga
     9601 caaagtccaa tttacattag ttgagatgcc gatcatgacg atgtctatcc caccgcaagt
     9661 tcctggagat tcgattattg atgtttcatt gaacaaataa ccaataacat tttttcaaaa
     9721 ataagaaaat gttgttttat agaacgaaaa ggtatatttt ttaaggagat atgggaattt
     9781 ttttattcct agtctcctta ttttatttgg aaaatgctat aattatctag aaggagtgaa
     9841 gctatgaacc atttagattt atctcagcgc ttagccgcag tgggtgactt tgtccctgaa
     9901 tccgctcgtt tagcagacat tggatcagat cacgcttact tacccgttgc attgatatta
     9961 agaggaaaaa tcgaatatgc agttgctggt gaagtcgttc aaggtcctta tgaatcagca
    10021 cgtaagcaag tcaaaaaaga tggattagaa gaccgtatca ccgtacgcct tgcaaatggt
    10081 ctagatgcta tccagccaca agatggtatt acagctgtca cgattgcggg tatgggaggt
    10141 tcactgatcc gagatatcct agaagctggc aagttgaatc aacgcttaag cggacaagaa
    10201 cgtttgatcc ttcagccaaa catcggagag cgtacattac gatcttggct gcaagaaaat
    10261 cagtataaaa tccaatcaga aaaaatactt gaagaaaata aaaaaatata tgaaatcatt
    10321 gtagccgaaa aagaacaaaa accagttact tacaatgaaa tggagctgat gttcgggcca
    10381 tttctgcttg aagagaaaag tgagatcttc aaatcaaaat ggacaagaga gcttcaacaa
    10441 agaaaagcta tccgtgaaca gctcaaacaa gcagctaatc aagaggcacg tcaaaaacaa
    10501 atcgagcagg aaatccaaat gattgaggag gttttaaagc catgacaatc agcggacgca
    10561 ctttcatcca aaagtttgaa agctattgtc ctcagtggct agctgaagaa ggagacccag
    10621 tcggactgca tatcggaaca ttggataagc caatccaacg agtaatgatg acattagacg
    10681 ttcgtccaga agtggtcgaa gaagcaatca agaaaaaaat cgatttgctg attgctaaac
    10741 atcctccaat ctttcgtcct gtaaaacggc tggttactga tcagccacaa gaaaaaatgt
    10801 atgcagattt gttgaaacat gatattgccg tctatgcagc acacacgaac atggatatta
    10861 tttgggatgg actgaatgac tggttttgtg aacttctcgg tattgaagtg gagagttatt
    10921 tagtaaagac tcatgagatt cattataaaa aactggccgt ttatgtacct gtggatcatg
    10981 cacagaaaat gcgtgaagta ttagctgcag ctggtgctgg tacacaaggt gattataccg
    11041 gtacaagttt tacctcgatt ggacacggtc gatttactcc ggaagctggt gcacaaccag
    11101 cgattgggaa agtagggaag acagaacaag ttcaagaggc aaaagttgag gttattttgc
    11161 cggaaactat cgaaaaacaa gtgattcaag ccatgcggtc agctcatcct tatgaggaac
    11221 ctgcttatga tcttttcgct atagatgaac cagtcgaaat gtttgggtta ggacgagtag
    11281 gtgaattgcc gcaagaaatt tctatagagg catttgtaga acaagtaaaa gaagcgttcc
    11341 aactagatgg actgagaata gtccagccaa aaaatgcaaa atcctctgtg aagcgcattg
    11401 cgatttgcgg tggaagcggt gaaaaatttt atccgcaagc aatcgcccaa agagcagatg
    11461 tctatatcac gggagatatc tattatcata cggctcatga tatgcaaagc gctgggttga
    11521 ttgcaattga tcccggtcat tatattgaat cgttatgcaa gcaacgattt atcgagaaat
    11581 ttgaatcttg gaaacaagaa gaaaattggg atattaactt tttcgtttct gaaacaaata
    11641 caaacccatt tcaatttaat taaaaggaga gaatactatg tacgaaaatc ttttgccacg
    11701 ttttttacga tatgtcaaaa cagaaacacg ctccgatgca acaagcaaaa cgactccatc
    11761 gactcagaca caagttgctt ttgcgcaaga attgaaaaaa gaattagaag agttaggctt
    11821 agctgatgtt ttctataatg aagataacgg attcgttatg ggaacattac caagcaatgt
    11881 tgatcatgaa gtgcgttcca ttggatttat ttcccacatg gatacagcag attttaatgc
    11941 agtaggagtc aatccacaaa tcattgaaaa ctatgatggc gagtctacga tcgtactaga
    12001 tgcggaagaa cgctatacat tgaatacaaa agattttcca aatttgaaaa attatgaagg
    12061 ccacacattg atcacaacag atggcagtac attactggga gcagatgaca aatcagggat
    12121 tgcggaaatc atgactgcaa tggagatctt gatcaataat ccttctatcc ctcacggtac
    12181 catcaaagtg gcttttggtc ctgatgaaga aatcggtgtc ggagcggata aattcgatgt
    12241 tgagcaattc gatgtagatt ttgcttatac agtcgatggt ggtcctttag gtgagttgca
    12301 gtatgaaacg tttagtgctg ctcaagcaaa tattacgatc caagggaaaa atgtacatcc
    12361 agggacggca aaagatacaa tgatcaatgc tctacagtta gcaatcgatt ttcataatca
    12421 gcttccagcc gatgaagttc cagaaaaaac ggaaggatac gaaggtttct tccatttgat
    12481 ggcattggat gggaatcctg aagaagcttc tatgagttat atcattcgcg atcatgatcg
    12541 tgaaaaattc gaagcacgca aagcacaaat cacacatatc caagaagagt tgaatcagcg
    12601 atttgatcaa gaacgaatca aagtagatat gtatgatcaa tattacaaca tgaaagaaat
    12661 cattgaaaaa gatatgagca tcgtggaatt agcgaaacaa gcaatgatcg agcttggtat
    12721 ctctccagtg atcgaaccag ttcgtggagg aacagatggt tcaaaaatct cttacatggg
    12781 tattccgacg ccaaatctat ttgccggagg agaaaatatg cacggacgat tcgaatttgt
    12841 ttctttacaa gtaatggaaa aagcaacaga cgtgattgta aaaattgcag aattgaacac
    12901 aaagagttaa aatcgaaaaa gaacagctta tgacaaggcg ttcgtcccaa tgatggaatg
    12961 tcatctgtct aaggctaaag ggcaggacaa tggaattggt tgtcccgccc tcttttttga
    13021 agagtaaata ggaggtaaag aatggaaaag ctgctagttt tttataacaa aagttcaggg
    13081 aaagatgagg gtgagaaatt agcacgctgg tttcaagatt atgtaaaaga aaagcagcca
    13141 gaattatatg tagaactagc tgaaactggc ccatcgattg atgatgcgga attagtcaag
    13201 aaagcagaag ccatagaagc tgatacttta gtaattatag gtggagacgg cacgattcat
    13261 catatcgtcc aagcgttcca aaaaacatta tctcaatacc atgtcggatt acttccaggt
    13321 ggaactgtca acaaccttgc acgtgttctt gagattcccc tcaaaaaaga agaagctgct
    13381 gacgtgatcc tggaaggcaa tgtacggaaa atagactatg gtcaagtcaa tgatgaagtc
    13441 attatctcta cactgacaat cggaatctta gcagatacag cagtttggat cagtcaagaa
    13501 gaaaaacagc gttacggctc gtggatcttt atcaagaagt tttttaagtt attgctgaag
    13561 aagaaaaaat atcatttgga tttagaaaca gacgaggagc attggaaagg aaaatcccaa
    13621 ctgttgacag tcacgatgtc taactccgtg ggcggtttta caaattttga cgactcagcg
    13681 accctagatg atggaaaatt tcatgtaacg atcgtacctt ccttagatat tttccgattt
    13741 attttttatt tgcctagaat catgagaggc aaattctata cgatccccgg cattacttat
    13801 ttcacagcca aacgcatgaa aatccaagcg caggaaaaat ctgtgggcac tcgaacggat
    13861 ggagacacga cagatgatct tccagttgaa ttatctgttg tatcaaaagg attaacagtt
    13921 tattcaccaa agaaagaaga aaaagcttag aaatagtagt taacagaaag ttggaagaag
    13981 agtaatggat gtattgttac acaatccttt gtggttttac cttttcattg tgaattttta
    14041 cttattttgt ctgatggggt atgataaaca tcaggctaga actagcggct ggcgtgttcc
    14101 tgagaataat ttgatatttg tcagcctgtt aggcggtggt ttgggaggat tgatctctcg
    14161 aaaagttttc catcataaaa ctcggaaaaa gaagtttact ataggattcg ctgcaggtgt
    14221 acttgttgat ttgattctca tttatttttt ccattaagga gcaggagatg tcgtctaaag
    14281 gaacgaaaac taaaatcatt ctgaatctgc ttttgctgat tgtgattttt gccattattt
    14341 attatttaat caatcaatca tttgcagata tctttgccga attgctgtct accagtgttg
    14401 ttgttttggc agcggctgtt atattaggga cagtttacca aatcgctgaa gggcgctcaa
    14461 tcaaagaaat tgctgaacct ttcgcgccga attttacaac gaaagatggg ttcttgacct
    14521 ctagctatat tgcgttttac cgaatcgttt cgtttggtac aggaacgctg atctcggaga
    14581 tttattttta taacaaaaaa ggaatgaagc tatcccaggg agcaggggtg acagcactcc
    14641 atatgattat gtacaaactg gcagtgatca cttatgcatt agctggcttg gtcatccaat
    14701 tctctctttt ttattctaat ggtccatcaa tgatctggtt tatcatcgct ggtatccttt
    14761 tgacgatcgt gattgttgcc tttttattgg cgatgtccgt cagcttgaat gttcaaatat
    14821 tttttgtcag cttatcgaat aagttattta aaagtgagcg tttgcggaaa tgggtggata
    14881 catgcaatca gcagatctac tctttaaggg aaacggtcca aaccattatc caagacagga
    14941 ctgcgctatt gcggatttat ctatggaata tgttaaaact tgtattttgg tatgtacttc
    15001 cttatttgat tctgattgaa aaccatccta aaatagattt tctactgacc atttcgttta
    15061 tcagctttgc agtagtgctt tcaggggtta ttcctacgcc tgctggtatt ggttcctttg
    15121 aatttgtcta tttgttatta ttcagaccag ttgttggaac agttgacgca gtttcttcgc
    15181 ttttactgta tcgtttcagt tcctttatct tgccatttct ctatggattt gtgtatgtga
    15241 ttgctgaacg gcgaagagtg atcaaagaag aaataataga agtaaaaaaa gagaataaag
    15301 aaaatcaagg gtaggtcttt tataagatct acccttttta tcaaatcaaa gaaaaacgtt
    15361 atggataaga taattttacg tttgtttggc tcttttttta tatacataca atcaattttg
    15421 tttttttaag atttatataa gtcgagaaaa aaagtcaaaa aactatgtgt atattttgac
    15481 caaaattgac caaagcgata taatagtttt tgtaaagatc aaagaaataa gtgatcttac
    15541 ctttaattag gagggtatac ctgtatgaat attgagaaaa tgactacgac gcttcaagaa
    15601 gcgattgctg aagctcaaca gattgcggtc actcgaaaac atcaagatat cgacattgcc
    15661 catgtatgga aaatcttttt acaatctaat cattttggtc gaaatttcta tacggatgcc
    15721 ggattggatg tcgaatcttt tgaacatgaa attgatcgtc tactggatga gtatccagtt
    15781 gtttctggtg gaaacgtcca atatggacaa aacctcagcc agaatttctt tcgattattg
    15841 aatgaagcag accaaatacg tgaaagcttc ggcgacgagt ttctttcaac ggaagtcgtt
    15901 attttagcgt tgatgaaatt aaaaaattat ccgttaactg tttatttgaa taaaaacgga
    15961 ttatctgaaa aagaattgcg taaaaacatc gaagagatga gaggaggaga aagagtgacc
    16021 tcacaaaacc aagaagaaca atacaaagca ttagaaaaat acggcgttga tttagtacag
    16081 caagtcaaaa gcggaaaaat ggatccaatc atcggtcgtg atgaagaaat ccgtgatgtc
    16141 atccgtattc tttcacgaaa aacaaaaaat aatcctgttc tgataggaga acccggtgta
    16201 gggaaaacgg caatcgttga agggcttgct caacgtatcg tacgcaaaga tgtgcctgaa
    16261 aatttaaaag ataaaacgat tttttcatta gatatgggtg cattgatcgc tggagcaaaa
    16321 ttccgtggtg aatttgaaga aagactaaaa gcagtcttga aagaagtcaa aaaaagtgat
    16381 ggacgtatcc tcttgttcat cgatgaaatc cacaatatcg taggggcagg aaaaacagaa
    16441 ggaagtatgg atgccggaaa tctgttgaaa ccaatgcttg ctcgcggtga attacatttg
    16501 atcggtgcca caactttaga tgagtaccgt caatatatgg aaaaagacaa agcgttggaa
    16561 cgtcgctttc aaaaggtatt agtcaaagaa ccaacagtgg aagatacgat cagtattctg
    16621 cgtggattaa aagaacgttt tgagatccac catggtgtta acatccatga caacgcatta
    16681 gtagcagcag ctactttatc tgaccgttat attactgatc ggttcttacc ggacaaagca
    16741 atcgatttga tcgatgaagc cagtgcaacg attcgggtag aaatgaactc tatgccaacg
    16801 gaattagatc aagttactag acgtttgatg cagttggaaa tcgaagaagc tgcactgaaa
    16861 aaagaatcag atgatgcaag taaaaaacgc ttgaaaaatt tgcaagaaga attagctgaa
    16921 cttcgtgaag aagcaaatgc gatgaagatg cagtgggaaa cagaaaaaga agaagtcaat
    16981 tctgtttcag caaaacgtgc tgaaatcgat aaagcaaaac acgaattaga agatgcagaa
    17041 aataactatg atttagaacg cgctgctgta ttgcgtcatg gtacgatacc tcaattagaa
    17101 aaagaattga aggaattaga agctaaagca aaagacagcg agattaagat ggttcaagag
    17161 tccgttaccg aaaatgagat tgctcaagtc gttggcagat taacgggtat ccccgtaacg
    17221 aaacttgtag aaggtgaacg agaaaaacta attaaattga atgaaacact tcataaacga
    17281 gtgattggtc aagatgaagc agttgatgcg gtcagtgacg cggtaattcg ttcacgggct
    17341 ggattgcaag acccaaatcg tcctctaggt tctttccttt tcctaggacc aactggtgtc
    17401 ggaaaaaccg aattagcgaa agcgttagct gagaacttgt ttgactcaga agatcatatg
    17461 gtacggatcg atatgagtga atatatggaa aaacatgctg tgtctcgtct agtcggagct
    17521 cctccaggct atgtaggtta cgaagaaggt ggtcaattaa cggaagctgt cagacgaaat
    17581 ccttatacaa tcgtcttgtt ggatgaaatc gaaaaagcgc atcccgatgt cttcaatatc
    17641 ttgttacaag tcctagatga cggacgcttg actgattcaa aagggcgagt agtagatttc
    17701 aaaaatacgg ttctgatcat gaccagcaat atcggttcac agttactgct ggaaggcgtg
    17761 actgctgatg gaacgattcc agaagcagtg gctgaacaag tcaacacgct attacgtgga
    17821 aacttcaaac cagaattctt gaaccgaatc gacgacacga ttttatttac accattgagc
    17881 ctagacaacg tgaaaggaat cgttgacaaa atggtggcgc aattggcaca acgtctggaa
    17941 catcaagaaa tcctgctgac aatcagtgat gaagccaaaa cgtggattgc tgaaaatgct
    18001 tatgaaccag catatggtgc aagaccattg aaacgattta tcactaagga agtagaaaca
    18061 ccactagcta aagaaatcgt tgcaggacat gttatgccta aatcaaaagt aacgattact
    18121 ttacttgatg gacaacttca tttcaaaaca gaagagctag aagaaatcgt ctaatcttcc
    18181 attgagacta taaaagaaaa aaggggtctg acacaactag tgtcagacct ccttttttca
    18241 aataaacagt gttccagaag tagtttcttc gaaaaataag ccgaaatttc ttgaagctgc
    18301 ccgcttctgt cacaacctct tttattaggt atttttcact ttttctaatt tataactttc
    18361 aaagtaacgc tcatcttttt tactttgaga ccatgcaaac aatcccatta aggcagcacc
    18421 tatcgtattt gtcagcaagt cgcccatcgt atccatcaat gctgctcgtc cgacaaacag
    18481 tgtgccatca gaagcagcaa aacgttgaag attcatgcct aagaactggt cgcataagaa
    18541 ttcccagaac tcccaaaaca cgccgcaaag tccagcaaac gcaaagccga ataagaggaa
    18601 caaccaagga ctggtttttg atatctcagc atctttcatc aagtaaccaa tcaatccata
    18661 gccaagagct gtcaggacca ttggactcac cgcatgtaag attttgtccc aaaaagagat
    18721 gatactgatc aaatgcatcc ctgtgcctaa aaagacagag atgaacaaga aaaaccagta
    18781 aaacaaaacg attgctgctg gtattttaag tttgaaaact ttcaaaatga cttgtggcat
    18841 gaaaatcaat gcaatcccta ataaagattc cacgataaat gtgattcctt gagaagtcga
    18901 atatttttgt gtgataaatt cataaaaatt atagcagaca acgaatacac caaaagcaag
    18961 taaagctatt tgcacctttt tgatttcttt aatcactgaa agtccctcca tctaaaaatc
    19021 tttttacttc tgaaagcaac tcaatttctg aagaaaccac ttttccgttc aatttgatca
    19081 aacctattgt atataagttc aggtagtgaa attgattttc agctgtttct tgtagtgcag
    19141 cgattttttt cgggtgggtt ccgccttgct gtcgagtatc agtatataag ccgatcactg
    19201 ggatgccttt cgcataagcc acaccgattt ccgatgctac cccggcatcg atcgtcagcc
    19261 catctagtaa agcaatcatt aaatcactag ccaacacttt ttctgtgtca gcaagagcaa
    19321 tcattcgact gtctgcataa gcagttttgt cattgattgc ttcattttct tgaggaagat
    19381 agatcgaaag ctcagaagag agctctctga tttctttaac taactgttgg ttatataaca
    19441 aatcactttt agcaaacatt ggtgcggcaa aataaatttt catctaaaca tcatcctttt
    19501 tatcaaaaat aatcgctaaa gtaagcttcc atgtttggaa tgatacgctc tagtgacttc
    19561 agtgtttctt catctgtttc taaccgttcg attcttgcca aataagaagc acggcgataa
    19621 ttcatcatca agcaagtcaa tgtttggata tccagtcgaa cggattttcc tataggttca
    19681 tttaagacac ggacttgtcc ctgttcatcc catgttaaag cgaagacacc attattccaa
    19741 ggagcgacag gatcttcaat gatgaaatga aaagcatcag ctgttccaac aaacggaaac
    19801 cgttgaagga attcttttac atcaacgatc cgagccataa aatatggttc gatctgctct
    19861 ttgatctgac tatcttcaat caaaaatgct aaaggctcat ttttataaat atctccatgt
    19921 acccagtaga tcatggaaaa atgtgcggaa ataaagttcc ataagccatt tcgagcttct
    19981 tgatcaagat agaacatttc ttttacgtga aatatttctt cagctaccca gtagaacaga
    20041 acacctcttg gttcatggtt gctatcgtag tagacagcgg ctgtgcgctc atcttcattt
    20101 tcgaaacgcc aatactcttc ccaatgaaaa tcactgcgga ataaagcacc atggttttgt
    20161 tgggcaaatt tgtcataaac ggaaaatacg tctggatgat caactggtaa tcgctcaacc
    20221 ataccactta ctgggatttg tttaggtagc tgtgtatctc tgattttaaa ggaaagttta
    20281 tcagacatga tttcccatcc tttacgccga tagtagggga tactgtaagg atacaaataa
    20341 gagatccatt gcttattctt gcgcatatta tccaatgcaa cgataattag atcttgcatc
    20401 aatccatggt tagcatattc tggataagtt ccaactccag tcacaccacc cattttataa
    20461 cgtgcaccgt gaatattgac ttcacaagga tagatagcga tttgagagat cagtttattt
    20521 tcgtggaacc atccgaacac tttcgatact tccaaaatcg gttttttgga acggataaaa
    20581 gctcgtttat tctcaaaccc gctttcctcg atgtctgctt cagtcacttg gaacacatag
    20641 gaaagcaatt cattgaattg atcgatatgt tcttgagtga ccggttttaa ttcaagattt
    20701 tctctaaaat ctttttgatc cattttttca tctccattta ttagcttgat aacagtatag
    20761 caaaattcta caaaaaaaac ttctatagct gactaattaa aaactcttta aattactgct
    20821 tttcgttggt ataatggaaa gtgctgatta tatgaaaaga ggagacgcta tggatataaa
    20881 gaaaatgaaa gaacgccaag agcagattcg taatttttcg atcatcgctc atatcgacca
    20941 tgggaaatct acattggccg atcgtatttt agaaatgacg cacactgtga cgtctcgcga
    21001 aatgcaagat cagctgttag actcgatgga tttggaacgt gaacgtggaa tcacgattaa
    21061 attaaatgct gtagaactca attacacagc gaaaaatgga gaaacatata tctttcactt
    21121 gattgacacc ccagggcacg tcgacttcac ctatgaagtc tctcgaagcc ttgctgcctg
    21181 tgagggtgcc gttttagtgg tcgatgcagc acaaggaatc gaagcacaaa cattggccaa
    21241 tgtttattta gcgttagaca atgatttgga gatcctgcca gtcatcaata aaatcgacct
    21301 acccgcagca gatcccgaac gtgtccgtca agaaatcgaa gacgtaatcg gaatcgatgc
    21361 tagtgaagct gtattagcca gtgccaaatc agggattggg attgaagata ttctcgagca
    21421 gatcgtggaa tatgttcctg caccaagtgg agacttagat gcaccgctaa aagctttgat
    21481 ctttgactct atttatgata gttaccgcgg tgttgttcta aatgtccgga tcacggacgg
    21541 tatggtcaaa cccggagaca aaatcaaact gatgagtaat ggcaaaacat ttgatgttac
    21601 agaggtcggg gtcttctcgc caaaagcagt tgctagagac tttttgatgg tcggtgatgt
    21661 cggttatatc acagcaagta tcaaaactgt ccaagataca cgagtagggg atacagtaac
    21721 gttagcagac aatcctgccg ctgaagcttt accaggttac cgaaaaatga atccgatggt
    21781 ttattgtggt ctttatccaa ttgatacttc tcgttacaac gatttgcggg aagctttaga
    21841 aaaactgcaa ttgaatgatg ctgctttaca attcgaacca gaaacctctc aagcattagg
    21901 ttttgggttc cgctgtggat tcctcggact tcttcatatg gatgtcgtcc aagaacgctt
    21961 ggaacgggaa ttcaatctag aattgatcac gactgcacca tccgttattt accatgttaa
    22021 taaaacggat ggtacgactg ctacagtaga taacccggca gattttcctg aacctgtaac
    22081 gattcaggat gtagaagaac cattcgtcaa agcacagatc atggtcccaa atgattttgt
    22141 cggtgcagta atggaacttt ctcaacgaaa acggggagaa ttcattacga tggattattt
    22201 agatgattac cgagtaaatg tcgtctataa tattccgctt tctgaaattg tctttgactt
    22261 tttcgacaaa ttgaaatcaa gcacgaaagg ctatgcctca ttggattatg aaatgtctgg
    22321 ttatcaaaaa agcaagttag tgaagatgga catcttgctg aatggagaaa aagtcgatgc
    22381 attaagcttt atcgttcacc gagactttgc ctatgaacgt ggaaaagcaa tcgttgaaaa
    22441 actgaaaaaa ctaatcccac gccaacaatt tgaggtgcca atccaagcag ctattggaca
    22501 aaaaatcgtt gcccgttcag acatcaaagc cttgcgtaaa aacgtcttgg ctaaatgtta
    22561 tggtggagat gtttctcgta aacgtaaact cttagagaaa caaaaagaag ggaagaagcg
    22621 gatgaaacaa atcggctccg tcgaagttcc gcaagaagcc ttcatggccg ttctgaaaat
    22681 ggatgagcaa gatagtgtga aataacttat aatcaatcga aaaacctatt aaataaacct
    22741 ttttgagtag atgcaacact gaggattatc tgtataaaag attttaaact gtcatttggt
    22801 tatcacggcg atactaaaat taacaaaatt ggaatatttt tcttgaagat ttttagctgt
    22861 cagtatatga tgaaagcatc tcataggagg tgcttttttc atggttgata attcaagtgg
    22921 aagggttctt aaatctctaa gaaaagagaa aaaactatct caaaaaaagt tagctgattt
    22981 agcaggtatt tcacaaagta ctttagttaa atatgaaaaa gggtcaagaa aaatccctaa
    23041 agacgtagat aatactctaa gcaagattct gaatatagaa actctaataa aagatgagga
    23101 agataagatt gagattctca tcggtaaact aattgcatac agagatatga ataagttact
    23161 taacaaagag ttagctgata atataggaat tagtgaagta ttactcagtt atgtgttaaa
    23221 tagaaagaga aatccgtcaa aagaaatgca aaaaaaaatc gatatttttc tattaagtaa
    23281 tgaaaaagaa attttgaagg agattaatcg tgatagtgag atatttagtt tatcaaaaga
    23341 cgataaaatt gttatgggaa aaagaatacg agaagtccga aagaaccggg aagagacgct
    23401 tgaaaaattt ggtaaaaact ttaccatcta tacaggcaaa aatgttataa gtagatggga
    23461 aaaaggtgtt tcccaaacaa aaagatatta agaaacagcc catgtttacc tgcttgcaaa
    23521 caaaagaata ttgctactag actaagagat actacataag tgtgttggta tctctttttt
    23581 gttgccgtga aacagcagac tatttcattt ctgcttgatt accttaaaac ttattagtct
    23641 atggtttgtc aagggcttgt tgcgtgagaa atgctgaata tcacccttta caaaacatag
    23701 gctgataagt aacttttcaa aagcagaaaa gaaatggcaa tgcttataac aatatgatat
    23761 aatgcagatg aagacaaaaa aggaatttgt cgagctggtt agttcgagat aattttgagt
    23821 ttgttaagat gtggtgcact tgatggaatc acaggtacga catcatatta tggaggatga
    23881 aatagatgat aggtttgatt gttgcgaggt caaagaataa tgttataggc aagaatggta
    23941 atataccatg gaaaataaag ggagaacaaa agcaatttag agagttaaca acgggtaatg
    24001 tggttattat ggggcgaaag tcttatgaag aaatcggtca tccgttgcct aatagaatga
    24061 atattgttgt ttccaccaca acagagtatc aaggagataa tttagtttca gttaaatcat
    24121 tagaagatgc attattattg gctaaaggac gagatgtata catatctggt ggatatggac
    24181 tatttaagga agctttgcaa atagtagata aaatgtatat cacagaagta gatttaaata
    24241 ttgaagatgg agatacattc tttccagaat ttgatatcaa tgattttgaa gttttgatag
    24301 gggaaacact tggtgaggaa gtgaaatata cgagaacatt ttatgtaagg aaaaaatgaa
    24361 ttgagtaaat tttggattta gggtgttttc ataaatatat tgctttttat gcatatataa
    24421 attgttgtaa gacaaattcc tgtttgtatt tataaaagag aaaaaatgag aaaagtagtt
    24481 ttatttattg ccatgagcct tgacggatat attgcggacg gtaatggtgg agtagcttgg
    24541 ctaaatggtc atggaaatga caatgaaaac atcgacactt atacagaatt taccaaagat
    24601 atagatactg tcttaatggg gtggaatact tctcatcagg ttgttactga actttctccg
    24661 caagaatggg tatataataa atttacaact tatgtattaa cacataaaga gtgcaattct
    24721 tcccaacaaa ttcattttac aagtgaaaat cctgttttat tattggaacg gctaaaacaa
    24781 gaagcaggaa aggatatttg gatttgtggc ggagcaaatc ttgttcagca gttggtaagc
    24841 aaaaatatga ttgataaata ttacatttct gttattccta ctctgttagg aaatggggtt
    24901 cgtcttttgg gcaacataga cagggaaata aagttaaggc tttgtaaaac acagacttat
    24961 aacggaataa ccgatttgat ttatatgcgt agataactag agagaaacag aaaagctgtt
    25021 aaaccgacgg agcgatccga ccacgttggc gggaaaatcc ttaagatttt tccgccatgc
    25081 ttgcaagggg gcggttcgct tcggcggttc ggcgagcttg cgagccgttc aaagcccccg
    25141 ttatctaaca aggggggcac aaaaaacaag aaacactata cactaacaag cggaaaacgc
    25201 tgtatttata aggcaaaacc ccatttttac agtagtgata taaattgtac ctatatcact
    25261 atgaaaattg aatagtaaat atgagaaaga cagttgattt caaaaaataa gaaattgatt
    25321 gtcgttttct tttgcagaaa tttaagtgca ggcaattatg gtagttgtcg taattgctgt
    25381 cagctcagtg tttatcactg atggtgtgaa agatttacgg ttggagatgt tcaataagat
    25441 tattggtgct taattatttt tattgtagtg ctgatatgag aatgttataa ttggggtata
    25501 aaacatacaa ataaatttgc tgaaaaatga ggtatcaaaa tatggaaaat gaattactgg
    25561 aaaacttagg aagacttcac acaactgaac ttggcgttat tagaattaaa aagaacttat
    25621 ctttgaatgt agaaaatgta attgaatggt gcaaagaaaa aattagcctt tctaatgcgg
    25681 aaatcacaag aaaaggaaaa aactggtata taacgattga taattgtatt ataacggtaa
    25741 atgcgtacag ttataccgtt atcacttctc acaaggtaaa atgataaatt tttctataaa
    25801 ggaattaaac gcatttgcag ttattgggca ggaagtagaa ctgactaatt atcaaaaaaa
    25861 gaatattcag attagtacac agttttggag aaagtttaac agtagtttga aaaaagcgta
    25921 tctttcacaa tcaggaaatt gggtaaaata tgcttttatg gaaagaagaa atggaaaact
    25981 ttattatttc tgttctattc cccaaagaac cattacccca gagggctttc tgtataaaga
    26041 aataccgtct tataaatatt tggttgtgga gcatattggt gctatggata aaatatatga
    26101 aacttatggc aagatttatg aagaaattat tcctagtaca tcgtatattc ctataaaaga
    26161 tattatccta cactttgaaa aatacgatta tcgttttcat tggaatagtg ataattcagt
    26221 tattgaaatt tggataccta ttcaagatta gaagcaattt tatatccata cacacaaagc
    26281 agttagtctt aggattgact gctttttcta tacagatttt taatgacagg caattatcaa
    26341 ttatggtagt tgcctttttt gattggagga attgaagaat gaatgataaa aactttattg
    26401 aagaactaag acaaaagcgt gaggaatacg gagtaacaca aacaaggctt gctgttgcct
    26461 gtggtatcag ccgtgaatat tacaaccgca ttgaaaaagg aaaacagcca ttgaatgacg
    26521 aattaagaga aatcatagaa aaacagattg agcgtttcaa tccgcaagaa ccactattct
    26581 tattgattga ttactttcgt gtccgctttc ctactacgga cgcattggcg attatccgtg
    26641 atgtattaca actgaaatct aattacatgc tttatgaaga ttatggaaaa tacggatatg
    26701 aaagcaaata tgtacttggc gacatcaata tcatgtgttc catgcaggag catttaggtg
    26761 ttttattgga actgaaaggc aaaggctgtc ggcaaatgga atgttatcta ctggcacagg
    26821 aacgctcatg gtatgacttc atgctggatt gtatgacggc tggtggtgtg atgaaacggc
    26881 ttgatttggc tatcaatgat aaagcaggaa tattggatat tccaaagtta aaggaaaaat
    26941 acaaggctgg cgaatgtatc tcctacttcc gtatgcagaa agattacagc ggtacagaaa
    27001 aatgcggtag cgatttacca aagaatacag gagaaacctt atatctcggt tcaacaagta
    27061 gcgaattata tatgtgtgct tatcagaaaa attatgagca gtatgtcaag aatggcacag
    27121 aaattgaaga tacggagatt aagaaccgtt ttgaaatacg catgaagaac gaacgagcct
    27181 attatgcggt tgtagattta ctgacctatc gggacgctga acgcaccgct ttttctatca
    27241 tcaatcatta tgtccgcttt gttgacagag aggacgacaa gccaaaaagt caatggataa
    27301 caaatgatga ttgggcatgg tttgtagggg aaaacagaga gccgatacgc ttaaccacaa
    27361 agccagagcc ttacacttta caaaaagcgt tgcattggct acaaagacaa gtcgcaccaa
    27421 ccataaaaat ggtacaggca ttagacagag aaaatcgtac aacgatactg aaagatatga
    27481 ttgagcaggc agaactaaaa gacaagcata aacatttatt acaattagag aaatcaacca
    27541 tagaagaacg tatagatacc gctgttccac aagagaatga cggtattttt taatgtaatt
    27601 gaaaaatttc agatttagtc agcaaagagc tgttttcatt ccctatgtga agtgaaagaa
    27661 gaaaaataaa ttttttatta aatctgcaac aaaatggcta cttgcgtaca gatatggtgc
    27721 gagaaaagga aatctaaact ttttttgaaa ataggtcatt aaatcggggc ttgctgtccc
    27781 tatatgaagt gaaagaagaa aaaagttttg aaaaaatgac ggaaattcgt gattagtgga
    27841 cagtcttctg tgaaaagagg aaaaacatca tcattttgta ttcaaacagg cattagcagt
    27901 tgagtgttga tgtgaaaaga tgaaaatact ttgttctcaa cttaacaatt taaggtttcc
    27961 gttccctata tggtgcaaag aaaatatttc attctattgt tggcagtaac ggtatggttt
    28021 gggtagttag ggtgtgaaaa ggaaaatatt cttttttcat catcaactta gcaaaatgac
    28081 attttctatc cctatatggt gcatgaaaag aagttaaaat ttttccattt aaacttagca
    28141 aatggacgtt tgctgtacag atagtagtga aaaaggagaa aatcaaccgt tgattgccaa
    28201 aatgaaccgt tccatttgta ctaataatgg aaaaagtttt ggattttggt tacgtttctc
    28261 ctcttttcca acgcgatata taggaaagac gatttttttc tttcaatcgt tctttgacaa
    28321 ctgaataaag taattcaata cgtttgacag acagctagcc gttgaaacaa atacgccacg
    28381 acctttcccc tgcaagagcg agcgaaaacc tatttgtgtt cttgtaaaag atttgtcctc
    28441 ttttatcgcc atgacctgta ctgtcagata atgatactcc cgtacagcca cagcttgagc
    28501 attaagagcg tcgcacgcaa tgggtacggc tacataagaa ctatgcagag gtggaactcc
    28561 tgtgggctat gacaaaagcc gttgaattgc ttagaaagat tttacagaaa gggggtatgt
    28621 gttattgata atgctgtaaa aacaattcaa aagaaaaatg gcaagtgtgg cattggcaac
    28681 agaggaaaga caaagattgt agtaaaagag catttttccg aaaagggcaa aacaatggaa
    28741 gaacttctaa ctgatgtcat gctggaaaaa gcaaagcaga caatcgcata aaatcggtgc
    28801 agttgtaaga aatagattga atgacaaaaa gtacccgtgt tatactttac ttgcaagcag
    28861 gtattgtaaa cacgggttag ttataaagga ggataactga caatgaaaca acagatttac
    28921 aatactgcac tttatcttag gttaagccga gatgatgaat tacagggcga aagttccagc
    28981 attaccacac agagaagtat gttgcgttta tatgcaaaag aacatcattt gaatgtcatt
    29041 gatgaatata ttgatgacgg ctggtcggga acaaattttg acagaccgag ttttcaaaga
    29101 atgattgagg atatagaggc aggaaaaatc aactgtgttg taacgaaaga cctttcccgt
    29161 cttggcagaa attatattat gacaggacaa tatacagaat tgtatttccc tagtcataat
    29221 gtccgctaca tagcgattga tgacggtgta gacagcgaaa aaggcgaaag tgagattgca
    29281 ccatttaaga acatcatcaa tgaatgggtg gcaagagata caagccgtaa agtcaaatca
    29341 gcatttaaga caaagtttgc ggagggggct cattacggtg cttatgctcc gttaggatat
    29401 aagaaacacc ctgacatcaa aggaaaactg ttggttgatg atgaaacaaa atggattatt
    29461 gaaaaaatct tttccctagc ctatcaaggt tacggaagtg caaaaatcac aaagcagtta
    29521 agagcagaaa aagttccgac agcgtcatgg ctaaatttta caagatacgg tacttttgca
    29581 catatctttg agggaaaacc cgaaagtaag cgttatgagt ggacgattgc tcatgtcaag
    29641 gcgatattga aaagtgaggt ttatatcgga aacagtgttc acaatatgca gtctacggta
    29701 tcgttcaaga gcaaaaagaa agtgcgtaag cccgaaagtg aatggtttcg agtagaaaac
    29761 actcacgagc cgattattga caaggaagtg ttctatcgtg tgcaggagca gataaaatca
    29821 agacgcagac agacaaagga aaaggcaacg ccgatttttg cagggcttgt caagtgtgcg
    29881 gattgtggtt ggtctatgag atttggaacg aataagacaa ataaaacgcc ttacagttat
    29941 tatgcttgca gttactacgg gcagtttggc aaaggtaatt gttctatgca ctacattcgt
    30001 tatgatgtgc tgtatcaagc cgtattggaa cgcttgcagt attgggctaa ggcagtacag
    30061 caggacgaag aaaaggtatt gaacaagata cagaaagctg gcaatgcaga gagaatacgg
    30121 gaaaagaaga aaaaggcaag tacattgaag aaagccgaga acagacaaaa tgagattgac
    30181 cgtttatttg cgaaaatgta tgaagataga gcctgtgaga agataacaga gcgaaatttt
    30241 gtgatgttgt ccagcaagta ccaaaaagaa cagatagaac tggaacagca gataacaagc
    30301 ctaagagaag aactaagtaa aatggaacag gatatgatag gtgctgaaaa gtggattgag
    30361 ttaatcaagg aatattccgt accaaaggaa ctgacagcac cattattaaa tgccatgata
    30421 gaaaaaatcc tcatacatga agcaacaacg aatgaggata acgaaagaat acaggaaatt
    30481 gagatatatt accgatttat tggaaaagtt gagtaatcaa caagagtaat atttttaact
    30541 aagggaaacc ggtattaata ttccagatat tgaaaaacta atgaatattg cctatcttgg
    30601 taaggtcact gttccttacc ttatgtacgg agaagattat aagaatatac ttccaaaaga
    30661 tgaaagagtt agcgatttta aaaagataaa ttcttttagt atgggattaa ggatgaggaa
    30721 aattaggaaa gattattatc tagaaaggga ggagtttgga aagctttttt ctccttcaat
    30781 ttcaaaatgg tccatagata ggtatgagaa tggtagagat atacccaata ctaatcgaat
    30841 tatccaatat gcttatatag gaaatctttc tttagaattt ttgatttacg ggatataaaa
    30901 atagtttacg tcgatactta ttaagttatc gacgtttttt attatagaaa aaatttataa
    30961 aaggaggttt cttgatatga taagaaacaa aaagggtttg ttgaaagttg ctttactggc
    31021 agcttttttc taagtaactt tttgacaagc tcaatggcaa cacaagcgga agaagtaata
    31081 caagaactaa ctgttatgaa taacagctag ataaaatggg ctatgtatgt tatccaacaa
    31141 tttagtaatc actagaagcc tagcgaaagt tcgcttgata agttatagat gagtattgat
    31201 ttgtagtgtt tccaaatcaa aagggtacag agccacatga aatatgttgt cctctgcagc
    31261 gtcaggatgg gaatccatac catggagatt cggagatctg tgagggaata cttacgtggt
    31321 taatatgtca gttgtgttgg acgtagtaat ggtcatagtg ggtagattga ctgaattctt
    31381 atatgagaaa atgaaaccaa caagaagata gggttattta tacagaattg gggatctttt
    31441 ctggaaaagt aatcggataa tgcgagattc gtacggtctt ttttaaattt ctctaaaaaa
    31501 aacggcatcg aatgggttgg gtgattgata agcaatgaat catagactga tatagaataa
    31561 aaaatgattc tatttatctt tttacatcta tcgttttttc aagtagccgc aaattatatc
    31621 agcattcaac aatttttgta tacaagttct agtaaaagga tctgaagaaa aagttggttg
    31681 ttgtgaagat aaaaaaagaa tcaggtttta ctgagttttt cttcaaaatt tgtgttatta
    31741 ggttaggaca aagataagaa gaagtatgaa gatttaaaaa aggaatgagg aaaagatagt
    31801 aatttccgat tattggagtt tttttattta taaagaagaa gcgaataagt tgtgattcct
    31861 agatttcgcg cgtgattaat taatgagcaa aaaatgcgga aagttttagt gtttaataca
    31921 cgaggacaaa gtttcttagg tattgaaggc acacgtgtaa cggttgatgg gtggtgtgat
    31981 tgtttcgagg ttggaaaaca tgttgaactt atggcattta ctgagctaaa agataagaac
    32041 aacgtggaat ttttcgagag tgatattggt tgggacgatc atgaagaagt ttatggaaaa
    32101 tttattttgc ggaagggaaa ttcttatacg aatggggaag cataagtagc gatttgttag
    32161 agatcattga taggattgaa attgtcggga atatttatga gaatctagag ttatttgagg
    32221 tgatagaatg agtgatggtt ttgaacaagt atcaataatt aaaaatcaag ttcgggagat
    32281 tcttagaaaa aaaggctatt tggtagatag ttattttgaa ggagattacg aaacatgggt
    32341 aggtgtctat gctcgtccag agaataaacc tacctattta gatcctacga cgtcagaaga
    32401 tgcctattta caaaataggt atcgagtaga tggttttaag caagactttg cggagtggtt
    32461 tgaatgggaa attgaaaacg gagaagtaaa agaagaataa gagtacttgt tgtatcaaaa
    32521 taagccagta gaacaaccaa accagtagct agtaatgaca ataatactga ggaatcggat
    32581 cattatggta tgattgatat ttctcttcca gaagatctta agccagatcc tgtaacaatt
    32641 ggcaatagtg tcatgatttt tgattcatta gatgaagcta tgtcatatgg ttggaaagaa
    32701 attaaggatg aaggtagtaa ttggtatggc atgagatttg gtgatggtga agttgccaaa
    32761 aaagctggta ttccaattgg gaaatggaca gttgatttcc acgaagcagg ttcttttttt
    32821 gttctgtaat tatagtggga gggtaaaatc attgatgaaa tgtgttcaga taagagcgcc
    32881 agataaaaat agaagagaca gttcacgtcg ttatcacttt tggtaacggc gttttgtttt
    32941 attatataaa attctcagga aaaggaggaa ttcttgtgta tgcaaaaacg aaaatgaatt
    33001 ggttgaaagc actcgcattg gtggcttttt ctcaattctg tttcttggtg ggaactgctc
    33061 aagcacatgc agaagaaacg acggctatac aacctacgat ggaagccatt gcccaagtcg
    33121 cttctgaagt gacagaagtc caaccagcag aagccggggt cccagctggt gaagccactg
    33181 ttgaacaggc ccctgtgaca gaagcgccaa cggtcaattc caaaacgact ctcgatcaga
    33241 cgattgggga aacacaacac ccagggaata gtcctggtac ttcacaacca gttgaagaaa
    33301 ctgcctcaat tacaacccct gcttcagaaa cgtccactct agaaggagaa aaagctgccg
    33361 aagcaacgcc ttctgtgcag ccagagtctt ctgagaaaca agcggaagaa aagaaacgaa
    33421 tagaagaaac agtggaacaa ccagcggcta ctgctgacaa agaaggaaaa aatgaggaaa
    33481 acgttgaaaa aacaatctct tcaaccgcag ctagtcaaaa tcaaccaacg aaaccaaaca
    33541 aagaatctac ggctagtatt gaaaatcaaa agaaaaaaga gcagaacatt ccaaaaacag
    33601 gtacacctac actgttagta acagtaccaa ccaatcgttc ggttcgtgtt cgccgtgcaa
    33661 ccaatgcagc tgttttaggt ggtcggaaaa ttgattgggg cgaaaatatt ggtgttactt
    33721 ctagtccgaa caatctaaac ttcactttaa attatatggt tcgttttgag attaatggac
    33781 aagtggcgtt ttgtattgag cctggtgtct cagccgcaga aggtcaagtt tatacagcta
    33841 ctgctttgaa aaactatttg aaaaattcaa atgtacggaa aaaaacaagc ttgatctctt
    33901 atttaggata tgtcacaaat aaagacaaat ccgatgaaca atacattgcg gcacaattta
    33961 tgatttggga agctttgggc acaaaaatcc caatcaaaaa tatacgtgtt gattatgatc
    34021 gtcgaaaagc agaaattcaa cgtttgatta ataactttgg tgaaaaagca acttttaata
    34081 atcaaacaca tacggtaaaa attggcgaaa cgttgaaagt aaagaataaa aatgattttt
    34141 tgaaatatgt gaaagacatt caaaaaccaa aaggtgtcaa tgtatctatt cacggcaatg
    34201 aagtatggat tacagtcaca aaagaggcac cggataaagc aaaaattcaa ttgaataaaa
    34261 ttaaagttca aggtgcgcca ttagcctatc gtcgtccagg agctcaaaca attggtgtgt
    34321 tacatccaac agaacctaat gcgtctgtta ttaatttaca aattctaaaa caaggaaaca
    34381 ttcgtgtgtt taaagaagat gcggaaactg gtgtgaaagc acaaggtgca gcttctttag
    34441 aaaatgcggt ctatggtttg tatcaagcag atgggaaaaa gattaaagaa attaccttga
    34501 aaaaaattaa cggcaaagta caggcagaaa ttaaagatct tgatcctggc aaatatgttt
    34561 taaaagaaat caaagcgcca aaaggttatg tgctttctga tgaagcaatt gaaattgttg
    34621 ttgaacctgg aaaaactgtc aatgcgaccg caaaagatca agtgatcaaa ggaaccattg
    34681 atttagtgaa agttgctaat aaagatttag tcgattcaac gaatccagat aacaaaccaa
    34741 aattagctgg cattgaaatc actttgacgt caaaaacaac tggcaaagtg gtgaaaaccg
    34801 ttgtgacaga caatgatggt tatgctactt ttggtaaaaa taccgttgtc tttgatacgt
    34861 acattctttc tgaaaccaaa ggaaaagaag ggtataaact atttgaacca cttgaagtca
    34921 caatttctga aaatgggcaa actttccatt atgttttaga agataaagta attgaacaac
    34981 gtcttaaagt ggtgaaagtg gatcaagaaa caggaaaagt gattccactt gctaatacag
    35041 aattcaagat ttttgatact ttagccaatc gttatgtcac aatggagatt ccaaatgata
    35101 cagaaacaac ggatatcttt aaaaccaatg aaaaaggctt tttcctaact aacggtacac
    35161 ttacttatgg aaaagatcgc tatcgtttgg aagaaatcaa agcccccgta aattacgttt
    35221 tgaatcaaaa cccattagtg ttctcgatta ccaatgatac agaaccgatc aaagtgatcc
    35281 attttgcgaa ccgtcaagca cggaaaagtg taaaattatt caagtatgaa gaatggaaca
    35341 agaagaaaac gccgctcgca ggtgtgaact ttaccttgta taacggtaaa aatcaagcaa
    35401 ttggtgaata taccactgat caaaacgggg aaattttagt gaaaggtcta gttgccgatg
    35461 actattactt cttggaaaat gccccattag aaagtttcca accaaataca gataaacaag
    35521 cattcacggt tgcattcaaa caaaatgcgc cagatgatgg ggaaacgtta gtggtttctg
    35581 tacgtaatta cttgattcca ccaaaactag aaacacaagc gtcaaataaa gccgatggtg
    35641 aaaaagtggt tgatccatta gaaacgatcg tcattaaaga cagtgtttct tataccaact
    35701 tgtttgtcgg aaaagaatac accatttcag gagtattgat gaacaaggca acgaatgcgc
    35761 caattttaca agatggcaaa gaaatcacaa gtaccttggc ctttattgca gacaaagtca
    35821 atggcacaaa agaccttgaa tttgtggtta atgctagtgt tctgaaaggt caaacgatcg
    35881 ttgtttttga aaaacttttc cgtgatggca ttgaagttgc agcacatgcg gatatcaacg
    35941 atgaagccca aagtgtgaaa gtgaataatc caaccgttca taccacggct gtctttgaag
    36001 acggattgac agtcgcagac ccaacaggat tgtttacctt aaacgatacc gttgaaatta
    36061 ccgagattct tccaggaaaa gcatacttgg tcaaagggat cttaatggat aaagcaaccg
    36121 gtgaaccctt gcttgtgcat ggaaatacgg tagaaacgag tgttggcttt attgccaaag
    36181 cagaaaatga aacggtgatc gtaccattta cctttgattt gacaggtata aatggtcgtg
    36241 aaatcgtcgt gtttgaaagt ctttttagaa atgatgaaga actagcaaac cataaagaca
    36301 tcaacgacaa agggcaaacg gtacgagtaa ctaacccaag tgtacgtaca acggctacac
    36361 ataaacccac tggcttgaaa gaggttaatc cattaacgaa agtcaccatt acagacgctg
    36421 tgaaatacca cgatttggtc gttggaaaaa catacacagt caacggtgtt ctaatggaca
    36481 aagtaacgga aaaaccagtg ctagtagatg gaaaagaagt cacaagtacc ttaacgtttg
    36541 tggcagaaac aacggatggt acagtcaatc tagactttat tctagacgca cgtgcgttgc
    36601 gaggcaaaga agtcgtggtc tttgaagatc tgtttagaga aggcgtatta ttggcttctc
    36661 acgcagatat taccgacaat gaccaaacca tcaaaatcag taatccaacc attacgacga
    36721 aagcgacgaa taaaaatggc ggaaaagaga tcttggcctt gccaaatcaa actgtgcttg
    36781 aatgggtcaa agtagacggt cttgcgattg gtcaaatcta tcgcttaatt gttcaaggct
    36841 acttaacacc agacggcaca ccatttgaag gcactcatgc ggaaaaagtc tttgcggccg
    36901 ataaagaaat gatggaattc ttatttgaat tcttagtgga cggtcgcaat cttgcaggaa
    36961 aaggcttgag ttttgcggaa tggctccaag cgaaaacgga agatgagaaa gaaacgtttg
    37021 aagaagtggc gaaacacaat gtagatctaa caaacaaaga tcaaacggtt caaattgtgg
    37081 aagcgccaaa accaccgcaa ccagtgaaac cagaacaacg ggttaaacca gctactgttg
    37141 taccaatgtt gccaaaaaca ggtgaacaaa caagtagtat acttatggtt cttggattag
    37201 tagtattagt cattgcttta ggtataacac tttataaagt acgtaaagcc aaagattagt
    37261 catgaggaac aagcggttag gatttttaac cgcttgtttg attgtaatgt agaaatattt
    37321 agaatttatt ttggttttta agaggaggaa aaactttatg gcagaaaaag cattgcgtat
    37381 gaagaaagag tttttaggtc aagtattttt attgggttca cgggaaccta atccaccaaa
    37441 ggaaattaat ggtgtgtctg ggcgatatgt tcaattacaa gcagagtgtt cgcgagaaga
    37501 acagcctgct ttttttgttt atctcacagc tgaagaggat aaaagattac gattaccaga
    37561 aaaagaggtg cgtatttcat ttgaagaagc ttattttgtt tttcgtaaag aacgagtgaa
    37621 tagtcgtgaa acaaatgata tgggacaaac agagcgtcga acaactggct atcaagatgt
    37681 tggtgtcttt ttaactggtg taaaaattgg ggaggttttg taagatggga ttaaaatttc
    37741 caaataatta tgacattaca gaagcattag atgaaacttg tttaggagcc gtacgctttg
    37801 gcgcattaga agagtctgat cgtgtatttg ataatgaaac aggcgattat acgggagaaa
    37861 ttcgatcaca gcgagcacaa ttagtttttg gaaatccaga tgaaccaaag attgcacgac
    37921 gagttaaatt tccagcagat gtagatttga ctggttttaa acgacgtgat cctgtgaaat
    37981 taattgatcc agaatatcat gtggtatata ttccagcaca agatggcaat cgtgaatatt
    38041 cagatttagt gatttatgcg aaaggattag agaaagtaga agctccaaca aataatccta
    38101 atatgaaaca atcacaagaa aaaggtttag atcaaaaaca accaagtgtt gattctaagg
    38161 aaaaagagaa aaaataaggt ttttttgaaa gaataggaag gagtcttcct attcttttta
    38221 tctaagatag aaggaagggg agattttgaa ttcagataaa accaatcaaa tactttgaga
    38281 gattgtgctt gttatcaaaa tatccaacaa ttgattgagt attttggaga caatccaacg
    38341 atttttgtac aaacaaatgc atatatttgt gcggttattg ggcagtgtat gtttttacgt
    38401 gatcttgttc gtttttcatt accgtaccag tggaaacaag atcatcagga agtgatttgg
    38461 attcgtatag tacgaatatg taatatgtgt gcacaccctt ataaaaatcg attaaatctt
    38521 tttcgattat gtttttttac taaatgtgat attcctgtat tagttgcttt ttgtcaaaag
    38581 tttttagcac aggaaaagta aaaacagaaa ggaggaatgt gacaattgaa agctcatttt
    38641 ttcaagtatc gtggtcggcg aattcgctat ttcaatcgtt atttatggtt ttgctattat
    38701 ggtttctttt tgtttccatt tttgattctg ttaggttggt ttagttggaa agtattttat
    38761 ccacgtttaa gtacgttttc gaattggcaa atgtatctta ttcctggaat aagtattgtg
    38821 ttgtatttgt tgctggttag tgggttaatt ttagggttga tgcattggtc gcgactaaaa
    38881 gaaggatatt ttgcctctgt ttattggcgt cagttacttg ttcgaatgtt aattgacaat
    38941 cggtttgttt atacaaagaa acaagttagt gagaaacaaa caagggaaaa aatgagatta
    39001 ccaaaagttt atttttatca aaagaaacaa gaattagtgg tttcttttcc tttagatggt
    39061 gggcgttttc acgaacgatt tttaaaaatg ggtcatttgt tatctgaagt atttttgcgt
    39121 gatttaattc gtgaagaacg agaaaaagcc cgaatcaatt atgtattcct ttcagattct
    39181 ggtcggattc ctattgatca atgtatagca gaaaatggac gtattcattt aatgaaaact
    39241 ttggattggg tatatgatca atcaccaaat atgttgattg ctggtgcaat cggtggtggg
    39301 aaaacctatt tattgtattc tttaattcaa gcttgtttaa gtgttgggac agtagatatt
    39361 tgcgatggaa aagcggcaga tttagcagca ttaggtgacg tcgatgtatt caaaggacat
    39421 gtgttttaca aaataaatga agaaatgatt atttgtttac gaaatgcatt aaaagaaatg
    39481 aatcaacggt atgcctatat gaaaaccatg aaagatccta aatatgaacc agggaaaaat
    39541 tatgcttatt atgggttacc accgcatttt atcttttttg atgaatgggc agctttttat
    39601 ggttcgttgg atatggaagc gagaaataga gtcgataaat tgattcagcc attagtatta
    39661 aagggtcgtc aagcagggat gtacattatt ttagcaatgc aacgaccaga tgcagaatat
    39721 tttccaagtg gtgttcggga taatttaaca ttccgtattt ctgttggtcg attgtctccc
    39781 attggttatt taatgacttt tggagaagat tttaaaaata agccatttta caacaaagat
    39841 caacctggtc gtggatatgc ttttccagga tttgatgtac ctgtagagtt ttttgcgcca
    39901 tttgtttaca aagattatca ctttatcaaa gaatttgaga aatttactga aatgattgtc
    39961 tatgatttta cagtaaaaga ggatagtcaa gatcaaacga tgggagatga taatcagttg
    40021 ttacaagaac aactagagcg ccaaatgtat ttagcaaaag atccaaaagg aacaagtttt
    40081 tctgatgcgc atattttgta atcaactaag gaggtgaagt taaatggcag agagttgtta
    40141 ttatagagta gctacagcaa tacgaatgat taatccttct ctttcttcca gaacgtttta
    40201 tgattggttg aatcgtattg aacaagtaac tgattaccgc tttttgcgca aagaacgtgt
    40261 ttttacagga aaagttatta atcaagtatt gctaacgaaa aaagatatag aacgattgac
    40321 tcgattgtat cattatcgag tagatttaga agaggattta actttgtcaa tttatcgcgt
    40381 tttttctcct gaaaaatata gtgaaataac aaaattagat catttaattt tgtagttatt
    40441 atctatcggg agggctctag acgtagtctg gtagccgcac tctgcctggc ggtgcgcatt
    40501 aaggctgcga agcatgggcc tataatgcgc actcgctagc agcgtgtgca gctcacaaag
    40561 aggtcgtgcg cttgcgcacg gcctctttgt gtaaagcccc ccgatatata atatgggggg
    40621 cagaaataac ataacacata gaaaaaagtt ttataaaccc ttttgtatca agtgattatc
    40681 taaggtcagc agttgtacta cttttcccaa aaaacgaggg ggactagttg atatatcggt
    40741 gtttctaaag ggttaaaaaa aatcgatttt gttattttat aaaaggagcg agaaaatgac
    40801 accgattgag ctaaaaagct acagaaagaa gttaagtgca attcataata taagtggaga
    40861 taaaaagccg ctatcacaag caagatttgc gcaattgatg ggctgctcaa aagattacat
    40921 tagaaagatg gaacaaggga aaagaaaaat cccagaggat tttgaacaac gaatcaagga
    40981 acgctttcga ttgtatatga aaagcggaat agatcttcga gcaatgattg attatttgcg
    41041 tctttccttt tttgggacag actacaaaac agtgattcaa cgtgtattac gaatggatct
    41101 gacagaattt gaaacacgtc caacgggctt gtatcttttt gactgtcttt ctgttcgtgg
    41161 gaatatctgg gtgttctggc attcaaaacg aactgtaaca gaaaatgtac ttgtgcaatt
    41221 ttcaggacaa ggttgccggg aatatgagga agtcatgcgt gaacaacaaa cagattggcg
    41281 aacatggcta tattccattt ggaaaaatca aggaaagttg gaagctggtt atacacgtgt
    41341 gcaatgtagc cgattcgata ttgcgttaga tgaactttgg ggattggaaa cggaagaaca
    41401 tttcgatctc tttgaattac tagaaaaaca aaaagcaggt ttattagaaa tggactttaa
    41461 gagattccag aatattggcg gttgtttttt agatgatggc tattttcgaa gtgaaggatt
    41521 atctttgtat tttggatcgc gaaagagtcc tctctttttt aatttttatg agaaacgttt
    41581 tgaaattgcg aaccgagaaa aaatttcaga attagaagca ttaacgaaat atggtattta
    41641 taatcgatat gagttacggt tagccaatga gaaagcaaca caagcagtag aagcatttat
    41701 tttaggtgat tcaccgaaac gtttaggaga gattggcgtt ggtttaatta atgcaaaact
    41761 tattgtttgg gatagactgg aaagtgatgc acggattgtt gataaacgat gggcaaaatt
    41821 atttcgttcg atggaagaat tggattttac agtaaagcca gaaaaattct cattagatcg
    41881 ttcagaacgc tggtttttga aacaagtagc tccgacatta aagttgttac aagaagcaga
    41941 tcgtatttta ggaagagact ttgtacaaga agggattgat aatgccgaac taaatgacga
    42001 gcaacaaaac tatctagaat ggatgggaac gtcaggaggg aaaattgcat gaatgcatat
    42061 acgacaacag aatggctgcg cctgttggat ttaaaggctg caatcgaagc attaaatgaa
    42121 aagatggttg atttgtctta ttttcgtttt cgagttcctt atattgaaca agcggtaaaa
    42181 gctggacgtt atcaggaaaa agagaactgg caagaaattg cacgcttatt agaagttcgt
    42241 aagggatacg aacaagaact cgaagagttg gaatttagcc gaaggaaagg aaggctagaa
    42301 ttcattcgct tttatcgatt ttcattgcca atacctgcga ttttagcggt taaaaaaggc
    42361 tgcgataaaa tgaagatata tgaaaactgt gtggcagcac ttagcagcga aaaacctctt
    42421 atggaagaaa tttcattggt gactgtcact tgggaaatga gtcgccagcc aacagaagaa
    42481 cagacatatc tttctttaga agagattgag atagaattag aggaaattgg tcgctatgcc
    42541 acttgttcta cctattgtgg atcggtcatt agtattgctg gtgtgattgt ctaaatgaaa
    42601 aaaattatga tttatgttgg tgcgtattgg tcacgtgatc caacagtatt agaaaatcca
    42661 gaggcggtac actattgctt gcgccaatta ttctatctgt ataaagaacg attagaatcg
    42721 ttgattcgtc agttaccata tactgacaga cgtttagatg aacttcttct aaggtatcca
    42781 gcaatgtata aacgacgaaa aaatagattg ttaccagaag agtatcccat tgaaaaacat
    42841 gaacttgaag ggcgatttgt ggcttatttc tatgatgatg ttcgtatgcg cttagtagaa
    42901 caacgaatgg aaatagaaaa tgatcgctac tattttatca attattgtaa gaagcgtaag
    42961 tatcaagtaa ctgatgattt ttatgattgt attttacaag atggggaagt gattctatcc
    43021 aaaattgctc caagttttcg tgaacttgtg ccgattgatt ttttgaaaaa atgtcatttg
    43081 cggattcttc cgtaaaaaag agctataaaa ggaaagaaaa gtagaagcca aatcggtttc
    43141 tgctttttta ttttttttag gaaggagaag atggtatgtc actggaattt ttaggagagc
    43201 caattgaaaa ggaagagttc gtttcgcatt atatggattt gtttattcag gtgataaaaa
    43261 actttgtgcg attgatgaat tttatccacg cgaacaagac tatctagccg ctgaacgaat
    43321 aaaaatcagt ttattatggg aaaaattcac agatgaaaat aaccgaccgc cagattatcg
    43381 ctatttatca gattgtttaa cgaataatgt gctttctaaa gaatacctat ttcacaaacg
    43441 tgagaaaaat caaatgtcgg ttgaacattt ttgtgattgt tatattgcat tattgcgtag
    43501 tcaacagtta ttaacagtag aacgatatgg tgcagagttt ggttatgtct tgcaagctga
    43561 gcgtcataga gctacaagat gctatgaaaa agaagatcaa gtgattgatg gctatgaaga
    43621 attatgtatt cgaaacaatc gctatttgca acaacgttta tatgaacaat tgatgatgga
    43681 tttttcaaat ctctatagag ggtatgaatg ttcgatgatt caagaaaggt agaagaaaag
    43741 ggggaatttt tatgtggcga ttattatttt tggtggtatg tggtatggca ttgttctatg
    43801 tgtatcgtgt ctatctctat ccacgaatgg aacgatggac aagttggtat agagatcctt
    43861 taaaacaacg aaaaggattg aagcggtatc gttatgaatt acttgttgaa ttttcggatg
    43921 ggcgacaagc acagtattat ttttttgcaa actatccaaa atacaacacc agtgaactat
    43981 tgattcaatt attcaaaaat aatccatatg ttgggttaga agaaaacgga cgggagttct
    44041 tttatcgttc agataatatt agtgcggcgt ctatgaacaa aacacgaatt gcataaaaaa
    44101 ttggaggaat aatcatgaaa aaaacaacat tagcagtcgt aacaacacta ggaatttcat
    44161 tattttcgtt tcaattaggg agttcattgg tttatgcaga tgaaactgta gaaacaccta
    44221 agtcagaaat tgtagaaaca ttgccagggg aaggattacc agatgttgag acagagctaa
    44281 atggaggaac aacggaaaaa ccagcagaac ctgaacaatt gcagtcagag aaacctgaaa
    44341 aagagccagt gacaccagaa ccagagtttc ctgaatcaac tttaccgact gattcgatcg
    44401 aagaagaagg tgtgcatagt tcaacaacaa cggattcaag tatagtcaca actccggaac
    44461 aatcaggaac aaccagttct tctgaaaaga atactgattc gtcaagtacg gaacagccaa
    44521 cgatgtcgtc taccagtgaa gaacaaaaag aagaaccgaa acaacctgtt gaaaaatcag
    44581 aagcaattcc aaaagaaaat aaacctattg ttccagcaaa agaagtcaca gtatcggtaa
    44641 ccccaagcgg tgaaattacg acgaatactt ctcaaggaat gagtgtaccg attgtcacta
    44701 gtaatgtaga ggaattgacc catattccaa caccaaccac cccattaaaa gtagcaggtg
    44761 atcaaacaat tgttggtgta aaagatggta ttccattaat ccaagatagt gaagggaatt
    44821 tggtaaagga tttgtcgatt cctgtaaaga aacttccaag tggcaatatt gaaatcaaaa
    44881 cagcagatgg aaaaacaaaa gtcttaccaa agactggtga agaaatacat gttgcacttt
    44941 ctgttctagg aggagtgttg acaagtattg ctggatttgt tggatataaa agaaagagaa
    45001 aaggaataga aaatgagggt aattgaatgg actatttttc agaaaaacaa gcttatcgtt
    45061 gtcaatcgta cgtactagta aaaacatact agaaggagta gcttatgaaa aaacgacaac
    45121 tacggcggaa agaaaaagtt tatacagaga aagtaccgaa gcaaaagaaa atccattcaa
    45181 aaaaagcagt gaaatggatt tggtgtttgg ttttatttct ttgtttttca gggggcttgg
    45241 cattttttca atccatgaaa acgaaggttc aagtgtcgtt tttgaaagat gaaatccaac
    45301 aattacaaaa gaaagaagta caaagtcggt cagaattaac gtacacacct gaaattgaat
    45361 cctttatgaa tcgttttgtt gctttgtata tgaatacatt cgataatcat gaacaagaac
    45421 aacaacgtca agaaacatta aaaaaagagt tttatgcaca aaactttatt caagaaccag
    45481 gaagtgtttc aggtgttcga aaattaactg ctgcttcgtt tattggatta aaagaaattg
    45541 aaaccattcc aactgctagt tataaagtaa cttatgatat tcgctcgatg aatccagaga
    45601 gtaagaaaga aacaagtgtg acaatcacac aagtactcaa tcttcccttt tctatttcaa
    45661 acaagggctg tcgtattatt gcttatcctt attttacggc actaccaaag aatacagaaa
    45721 aacaacgaat gattacttat gatgacacat tatacgaaac ggttgatgcg tcggaagcga
    45781 aagatgttga aggatttgtg gaagatttct tagataagta tgcgaaaaac aatgcaaaag
    45841 atatgtcata catgatgaaa gaacctgaag gactcaatca aacagctaaa gttgatcaag
    45901 tagagatgaa agtattgcgt tataaagaaa cgaaaaaacc ttttattgta aaagcaacgg
    45961 tcgtctttcg agatggtgat acgtcacttt tacaaaaaga acaaatgacg attgtcatta
    46021 cgaaaaaaac aaatcagtat tatgttgaaa aattaacaca taattggttg gataggaaag
    46081 gagaagaacg gaaatgacac tgaagggaat tgtagatttt atattaacgc aaggtggcta
    46141 ttttttaata atggtggttg tttatctggg attgcgaaat tttatgaaat caaaagtagg
    46201 aaatgcatta atatctatcg cagcaggtgc cgcagtttat ttcttcttaa atgatccaac
    46261 acgtgtattt gatgcgtttg gtaaaatcat tgaaaaatta tttatggatt aggaggatag
    46321 tgaagtggat tgggaacctt atgattattc gattgtttat gcggaacctt atcgcgtaca
    46381 acagattaca agcaattggc gtcttccatt tccagttgca ttagtcaatg cagcaacttt
    46441 tttgttggtc gtaatctttg aatatttatt tttacgttca tttattggtt gggtcatttc
    46501 tttttttcca ccagcaggag ttgtttttta tataggactc ccctatttat gtgtgttagc
    46561 actggcaaaa ctaaaacctg atggaaaaaa agtgcatttt tatttatggg attggttttg
    46621 ttatatgatt cgtatgatga atggtgattg tgtgtattat aactgggaca aggtatcaaa
    46681 caatgcattg gaagaattac tttttgtgaa taagtatgtt tatttagagg attagaaaaa
    46741 gggacaatca actggttgtt ccttttttat tgggaggtga aattcattgg tgcttgtaaa
    46801 agaaccagta aaagcattca agaaaaattg tttgttaaat ggagaggatt gtatctgggc
    46861 ctactatcat gtttttccac gaacaatttc aaaaaacaca ccaaaaaaga cacaggaaat
    46921 aaaagaaatg atggctcgtt tactgttgct tttagcagat tatgaagatg tggagttggt
    46981 gatgtatcca cgaacaatga atttacggac gaagtttgac acattaggaa agggattttc
    47041 tcccgatagt caagcaattg gtgcgtatta tgcaaaagaa acagtgacat tgttggaacg
    47101 agaaggtcaa gtctatcgtc cttcatttat tttaggaatc aaagtcaaag aaaaagcaac
    47161 ggtggagagt tttcatgatg taataaatct aatctggtta gatttagcag gaagtttagc
    47221 acgcttattt ggattagaag tagatgattt ggaaactttg ttttctgaaa gtgatcctta
    47281 tgtaaaagaa gtgacacaat tactttatag cttttctatt cgtcccttag taaaaaaaga
    47341 gctgttgtat ctcaatcgtc tgcaatatat tcgaggaatg gctcacaaag tagaagaaca
    47401 aaataattgg gaagtactga aagacaatca aggaacgtat gtacgtatac cgaaggaaca
    47461 taaaggcctt cttcaattag aagatgagtt agggagtagt tatttagcat tgttgcctat
    47521 tggggaaaca cctgaaaata tgagaaattg tgatctattt caatttgctc aggatctttc
    47581 tttcccagca gaattgcgaa tgaaaattca ctatccacgc ttgaaaggac agggaggtat
    47641 tggtttaaaa ctgaattggc tatcggaacg gttcaaaaca gagcataagg aattggttca
    47701 aaatgatgaa gaacctagtg aacgcttatt aactgttcga ggattagtaa aacatttaaa
    47761 gcaacgagta gataatgggc aacctgtcgt cgattggatc gcatgtttta ttgtatacgg
    47821 tcaaacggtt gaagaagttc gtcaaaatag tgcaacggtt attcaacaac ttcatacgat
    47881 tatccatatc caccgtgcaa aaaatgatca acgagaattg ttctataaat gtttattagg
    47941 gcaaccattg ggacggcagt tacattggaa gcaccgaaca actgtagaag cagttggcga
    48001 atggttgttt tcagcagtat cagaattagg tatggaatcc ggctggtata ttggtcggca
    48061 agatacatta ggggatggtg gttctcgagg agaaaaaaca ccattagaag aattaattta
    48121 tgcgtcaaat cgttttgtct ttttgaatct tctagccatt gcggaaggaa tcaaaggtgc
    48181 gttgtttgat gcgcctcatg tagcagtaac tggaaaaacc ggtaaaggga agaccttttt
    48241 agttggcttg ctctttttgt atagttcgtt tatgaatgta caaagtttat ttgtggatcc
    48301 caaaggagaa aagcgcaaat ggtttacgaa actcattcaa gacccgtatt atcagaaaca
    48361 ttaccctttg tttgtagaac atttgcaaaa aatgagttat gtcacgttag atgctacaaa
    48421 tccccgtaat tatggtgtat tagatccaat tgtttgttta tcccgagtag atgcgaaaca
    48481 agtagcccag gatatgattg atgagttaag tccgttaggt accaatcacc ttttaaaagg
    48541 ggcggtatta aagggaatcc aagaagtttt agttcaaaaa gaagccggac aacaagttgg
    48601 cttgatgcat gtggtcgact atttagaaca aatggaacaa aaagaggttc gagaatatgg
    48661 tgagttttta cgcttgacgg tagaagattc gattttacgt ttaggatttt cttatggaga
    48721 aaacccggga ttagacttta atgccaaaac aacgatttta gagatccaag atttgaaatt
    48781 accaaatgac aatgtccgac cagaactata tacagatgcg gatcgaaagt ctttgtgttt
    48841 gatgattagt ttaggtcgtt tttgtgaaat gtttggaaaa cgagatagta gtaagaaaac
    48901 agcgatttat tttacagaag catgggtatt taataattcg aacgcaggac gtagtattat
    48961 tgcagcaatg gcacgtgtgg ggcgttccca gatgaatcaa ttagtgttag atacacaatt
    49021 tattggtgac ttaggttcag ataaagaaaa agggaatttt ggtgtcgtct ttgcttttga
    49081 tgaagacagt gagcgagaaa agattttgaa tcatttacgt ttggaagtaa atgaagcgaa
    49141 cttagctgaa atgagccaca tgattaaagg acagtgttgg atgttagatc cctatggacg
    49201 tgtaggaaaa ctcaatgtac acagtttgtt tgaagaaatg accgctgcat tacaaacaac
    49261 ggaaaaaaca agtcactctc aagtagaaga acaggatacg ttaatcatgc aatagaaatg
    49321 aggtgaaaca atggcttata taaagcataa ggaaaagaaa tggtgcgttt tgtttttttt
    49381 aacgattgga ttcggactgc tttttgttgg tggattggtg tatgcggcag aaaagcaggt
    49441 ggatcaatcg atctatgaga ttgggaaatt tcatattgat accttttctt cttatttatc
    49501 tgatagtgaa ttttcattag gcaaaatgtt atttggggca aatggcacag attttctaaa
    49561 aatgatgacg aatatgttct ttagtttaag taaattgatt tggcaaggcc ttgattttgt
    49621 cattgagaag ctctatgaag gagctgcaat gaacgagtta attcaccagt ttttcacttt
    49681 ttcggatact atttattcaa aaatatacga tcctattggt gcggggattg tcgtcttgta
    49741 tgtgttatat ctatttactc ttcgtatatt tagagggaaa cattacgcaa aaatggtgtt
    49801 tattcgattt ctcttcgttg tcattttttc aatggtttgg tttggctatg gtagtaacgt
    49861 acctagtaaa ggagaagctt ttaccaaagg gttaaatgat ttgtccgtgg aggtagaagg
    49921 ctttattttt tctgctacaa atagtctaga tgaattggcg acaaaagatg tcaatggtgt
    49981 tttagtgcca acgacacaaa aggaagccat tcaaaaagtg cgccaacttt attataaagc
    50041 ggctgttgtt gatccgtata tattgttaaa ttatgggaca acaaatttag aagaattgta
    50101 tcaagcagag attgaaccac aagaatttct agccaaggaa gcgtcaagtg aagaattatc
    50161 tgatattgag acaaaagtga ccactgctgc aggagaagat agagggaaaa agaaggctta
    50221 tcgtgtctat attcaaccaa ctaaagctgt ttataaagca gtcgttggtt ctatggtgcc
    50281 attgcttaat ctaagtattg gattaccact tgtagtgatt ggcatgattc gttttatctt
    50341 tcaaatgttg gtgttgtgtt tattacttgt gattcctttt tcattactcg cttcttttgt
    50401 tccagtattt gattatatgc tcatgaatac cttaaagtcc tttttgggct tgatgtttca
    50461 aaaatctttt tacagtgtga ttattttggt ggcatttttg atctataaca tagtagacga
    50521 tttaattcca atgaatactg tttttggttt tttaggaaat atgtttgtca aagcactcct
    50581 atcaatttta ctcattgtaa aacggaaaga tttattaaag aaactagggt taggagctgc
    50641 agatcaaact ataaacaaca cgaaaaacat agcaagtcat tctttgtctc aaatgaaaca
    50701 actgcctggt caactatcaa ctgctggaca aaatttggca atcaaaggtg caggattagc
    50761 agggaatgtg tatcgagcaa cgaatccact cgcttctgca gcgatacatg gatttcaaaa
    50821 gtttcaacaa aaacgtacac cacaagaatc ggtaaaaggg aggcaagtgg ttaatccctt
    50881 tgaactaggt gggcgttcaa atcaagcctt gccttatagt ggtcgtcatg ttcgttatca
    50941 tggggtagag cctgaaatgt cttctaccaa atcgaaaaca gagtggaatt ctggtctttc
    51001 aaatggtttg attccaaatt cgtccatgaa ttcagtaaga ccaaaacaac aggtacaatc
    51061 attggcacaa ttgagtaagc aacaagggaa taatcaaaga aaaccattgt taaataaagg
    51121 tatcgctttt gttggtcaat cgattccgtt gccttctgga aaagtacccg tgccacaatt
    51181 aacagctgct ggttctcttt cacaacagat tcgccaagtg aaaaatcagg cgaaaaatgg
    51241 gagttatcca gcaatgcagc agttattgaa ccaatactct gttcctaatt cgtcggtagc
    51301 cactctatca ggaaatcgtt ctgtgcaaca accggggcaa cgttcgtctg aaagtaaacc
    51361 gtcgatttcc gcaccaaaat cgttacaacc tgcattttct tctttagata agccaacaga
    51421 gcaatcggaa aaaatagaaa aggatcctaa aacactgccg attttggacg caaaaccagg
    51481 aactgatttt actttaccaa aaggacgaac agtccaaaaa ccattatcga agaaaggatg
    51541 aggaagaaat gaagaaaggg tgtctaggtt gtcttctttt ctttattctt cccttttttc
    51601 tattgccatt ctttttttca ggagaacttt ctgagcatgg aggagaagct acaggtctag
    51661 ctgtcgcttt taatggggaa tataccgaag gattaccgat tttttcagag attaaaggac
    51721 gtggtccaat cacagatgaa catgcgcaag cagcagttgg tgcagctgta aagtatcagt
    51781 tattaccgag tgtgattctt tctcaattag gctatgaatc agcttatgga cagtcacaat
    51841 ctggaagaaa cgatacgaac ttttttggga ttacctggtt tcctggttgt ccctacccac
    51901 aaggttctgc acgtggaatt ggtggttctg aaggtggttt ctatatgaag tttccgaact
    51961 taaaagcttg ttatgactat tatggcttta tggtggcgag ccaaagcaac tttaatcaat
    52021 gtgtgggcaa taaagatcct ggaagttgtt tattgattct aggtcgtgga ggctatgcgg
    52081 cagcaggtat taccgaaggg agtccgtatt atcgaggagc aatgagtatc ataacgtcct
    52141 ataacttaac ggaatatgat acttttgcga tcaagcattg gaatagccta ccaacaaaaa
    52201 aaacttcgct tattgcagga aaaagtaaag gcaatgcgaa ggttttggat cggatcattg
    52261 gacgatccgt aaataatggg gaatgttatg gtggtacggc atggtatgta tctcaattag
    52321 gtggcccaca gttaatgggt tctggacaca tgtttgcgat gttaataggg gaagattata
    52381 actggacaac ctatggttgg caagtaatca tgaacccaaa accaagtgat ttacaagcag
    52441 gagatgtggt gaattggcaa gcaggtggtg cattgtctcc tggaatctat ggtcacaccg
    52501 gaattataac agatgtttca tatggcggac aacatttctc tagtgtggaa cagaatgccg
    52561 agcaaggacg gattatggct cggtatcaac gcacgtacaa tcaaacaaaa attcgtagtc
    52621 tggttcgtaa ggtgaaataa gaaaggcagt gactagaaac gtgaaaaaag ggataatttt
    52681 agtatttagt tggttatgtt tgataggtct tactggttgt cattggtttt cttctgaaaa
    52741 acaaaaaaca caattgagaa cgacagaaga aacaatcgaa gcagtaaaag aaacaagtgg
    52801 aactcttcaa agtactgaaa gtaacagtca aattggttca ttagaagacg agacagcgca
    52861 acaaatgcaa atagatgaaa tgacaaaaaa tttcttaaaa gattttgcta gaaaatggag
    52921 taatttcaca gatgtttata aacgcaatca agctgtgagg gactatatga cagatcgttg
    52981 tattaaagac aatagtattg atgtagaccc gcatgtacaa atgaaaacaa ctgggaaact
    53041 ttaccaggtg acacaagata tagagaatcc ggatcaatat ttgttatttg gagaagaaac
    53101 aatgaataag gttactcaat ttgtattact tcaattgaaa gtagatcaag aagctcaaaa
    53161 gattgatgcg atcaagattt attatgtacg gagtgcgtat taaaataaaa aatgaacact
    53221 catatttatt atacaccgaa gaaatagaaa aaaacagact gtttttttaa gaaaaactat
    53281 gtcattcttt acttgaaaaa agttgttata ggacagaaag gataaaacaa aaacggaaaa
    53341 aatatgtctt atgaataact ataagaacta ttctattttt taggagatgg atacgagatg
    53401 aaaaaactaa ttggctatag tgtgatgtgt attggatttg ttggtgtggg attgtttgta
    53461 tcgactgaat ctgcttctgc ggctgaatgg tataatccta tctggtataa tccgaacatt
    53521 gaatgtcaaa aaggctatcc gtatggaccg acaaatctga aaaatggaaa atgtagagta
    53581 aattggaatg gcgttgtaga tagtgtaatt actggttcaa tggactctgc tctacatggc
    53641 tttacgggtc actagaagga ggaagaaaat gtctgaagag aaaaaagaaa tcgttgaatc
    53701 attagtagct ttaaaagatt ctctttctaa gattgaatat gttgataggc aagaaattca
    53761 aaaactaatt gatgatacta ttattgaaat ccaagatgcg cgttgtgaag gtataaaaat
    53821 ttctgtagct ttatctaaag taatagaaaa aatgaaccgt tcattagcgt ttaatggatt
    53881 gaagctagat agacaaacta gtctgatatg ggatcattta aaagacttgt atgacaagtc
    53941 taaaagaagt gaacggactg ctgtatcaat cttaaaaggc ctttggggaa tgaattcata
    54001 aacaagatat ttaaaaagta acttattttt tatggaggag aaattatgaa aagaataatt
    54061 aaaatatttg gtgttttagg tgttttctta ttaggtttaa gtacttttgt tagtactgga
    54121 acaagtgtgt atgccacaga aaaagtgaat acagttgatt tagaaataaa gaataaatta
    54181 gtagatgaat taacttttta ttttgataca gttggttttt tagacgaaca tggtgtatac
    54241 catataaagg attttggtgc tattcgtgaa cgaatcagtc aagataacga acaaggaaga
    54301 gcagcaagag tcttttatga acatattatt gttcctagaa tggagaaagt tgattggaaa
    54361 cgatatgctg gatgtgtagc cattaattct cttcctggag gaggagtggc ttgggctata
    54421 ggtacgcagg gagattttat tgaagcatta aaagctttta attttgaaaa agctgcggat
    54481 ttattattaa aaattgcaga aaaacaatta ggaaaagctg cagctaaaga gttagctaag
    54541 gtaaatattg tagcaggaat tgcagcagct gctgctagct gtgcattaga gtaaaagttt
    54601 atgaaaagtt tagaacaaga gcatatggct tttaaacaag caatgtttaa agaaaatatc
    54661 tatttaaacc ataactatat tcgtgtttct aaggcatgtt caccagtatt gaatatgctt
    54721 ggaggtggaa atggattata tcatttactg tttgtcgatg tttgttggtt aattttttta
    54781 ccagatgaac tagttatagt caatgaaaaa ataacaagta aaaatgaagt gtttaattat
    54841 tctttaacaa gaattaatta caaagagatt accaagtttt cactagaaaa agttcctttt
    54901 tggggagaat tttgtttaaa aattaaatgt aactggaaaa gaatgtattt ctatattgat
    54961 ggtgatgatg ctcttacatt cggtaaaact actttttcta gttttaattt tcagtttcta
    55021 ttaaaaaata atttttatgg tttattgaaa taaggttgcg aaggaagatg tagagttatt
    55081 tgcactgttg tgttggtata tctcttaatg ctgtgtcttt ttggggagat taattagtgg
    55141 agtgattata tgagtataga tgattgttta gaagaacaaa taagattatt tttaaagttt
    55201 ttaaaagtta aagttcaaaa taactacttc acatgttata gttatgcaca ccctgtttta
    55261 aatagtcttc cttttaattc tttagtgcaa ggattgatta caaatattgt tttattagtc
    55321 tgtacaccaa atgaaatatt tgtaaaaaag ataggcagtg gtatttcttc agtaagatta
    55381 aaagagaaag aatatactca aaagattatt catattccta agcctgaaat taagcgtttt
    55441 gagataaaag actattctgc tttagggctg ttctcaattg gttactggtg ataaaaaata
    55501 agaatactaa aactatacgt agaatataag taatcggcat caatcctaat tatgtgattg
    55561 aatgccgatt tttgttacgc gctattttta attatctgta agaagaataa ttttatttta
    55621 ctcatattcg ttttcacttt gaagaagtaa attgcaattt cttataagtt aagcagctat
    55681 gcaaaaggct atttattcta ttgtgaaata taagatgtag ttgaaacagg atatatagaa
    55741 tcaaaatacg aatcttattt tgatttttct agttttttga aaaaagcacc ctttgatcgt
    55801 tgtattagtg gaaaagagaa aaaggagcat acttatcatg tcacaaaact acaactaaat
    55861 atctaaacaa caccaatttg atgcctattg aaaaaaagta ttgcgaaatg aagccaagtc
    55921 tattagaaaa tgaaataata gaataaaaga aaatgggaaa ccgctgaatg atgtaaatga
    55981 aggtaagtat ccacgaacta attttgatga acaagatatc tattttttat ttgtattgga
    56041 gatactagtt taatatcaaa agttatcagc agtcataatt agttatccaa tgtaaaaagt
    56101 acaaacaata gttgttatgc agaatagttt atgaaatata ttacataata agaaaacaag
    56161 cgatagtcaa gtccacaatc ttgtgtaaaa gttcaacctc atca
//
LOCUS       DAFELK010000186        20943 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.051, whole genome shotgun sequence.
ACCESSION   DAFELK010000186
VERSION     DAFELK010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.051"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(101..544)
                     /locus_tag="LP433_003073"
     CDS             complement(101..544)
                     /locus_tag="LP433_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBL2007132.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(739..2079)
                     /locus_tag="LP433_003074"
     CDS             complement(739..2079)
                     /locus_tag="LP433_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2007133.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2361..3257
                     /locus_tag="LP433_003075"
     CDS             2361..3257
                     /locus_tag="LP433_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL2007134.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            complement(3400..4341)
                     /locus_tag="LP433_003076"
     CDS             complement(3400..4341)
                     /locus_tag="LP433_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL2007135.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4467..5588
                     /locus_tag="LP433_003077"
     CDS             4467..5588
                     /locus_tag="LP433_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL2007136.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            5846..7348
                     /gene="eat(A)"
                     /locus_tag="LP433_003078"
     CDS             5846..7348
                     /gene="eat(A)"
                     /locus_tag="LP433_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL2007137.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            7376..7942
                     /locus_tag="LP433_003079"
     CDS             7376..7942
                     /locus_tag="LP433_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2007138.1"
                     /translation="MVKENFVNEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQALAEKVVDLPVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELISYE"
     gene            8154..9215
                     /locus_tag="LP433_003080"
     CDS             8154..9215
                     /locus_tag="LP433_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL2007139.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9218..10114
                     /gene="murQ"
                     /locus_tag="LP433_003081"
     CDS             9218..10114
                     /gene="murQ"
                     /locus_tag="LP433_003081"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL2007140.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            10128..12110
                     /locus_tag="LP433_003082"
     CDS             10128..12110
                     /locus_tag="LP433_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2007141.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="LP433_003083"
     CDS             complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="LP433_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL2007142.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            12837..14261
                     /locus_tag="LP433_003084"
     CDS             12837..14261
                     /locus_tag="LP433_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2007143.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14438..15211)
                     /locus_tag="LP433_003085"
     CDS             complement(14438..15211)
                     /locus_tag="LP433_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2007144.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(15208..16113)
                     /locus_tag="LP433_003086"
     CDS             complement(15208..16113)
                     /locus_tag="LP433_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2007145.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16274..16594)
                     /locus_tag="LP433_003087"
     CDS             complement(16274..16594)
                     /locus_tag="LP433_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL2007146.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            17067..17753
                     /locus_tag="LP433_003088"
     CDS             17067..17753
                     /locus_tag="LP433_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL2007147.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17755..18699
                     /locus_tag="LP433_003089"
     CDS             17755..18699
                     /locus_tag="LP433_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL2007148.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18898..19542
                     /gene="pcp"
                     /locus_tag="LP433_003090"
     CDS             18898..19542
                     /gene="pcp"
                     /locus_tag="LP433_003090"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL2007149.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19621..20898
                     /locus_tag="LP433_003091"
     CDS             19621..20898
                     /locus_tag="LP433_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007150.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6757 a         3774 c         4370 g         6042 t
ORIGIN      
        1 cacaacctct gattcacggt gttccagaag tagcttcttc ttatttcttg aagttgatca
       61 cttctggaac atcctctttt tttatttgga tggataatgg tcattccatt tctttgatca
      121 tttttttcat tttgtcgatt tcttcttctt gtgcctgaat gatttcttcc gctaattttt
      181 ttacttcagg atcttttaaa tcagctcgtt tacttgtcaa gatagcaata gagtgatgag
      241 ggatcatcgc cttcatccac gccgtatcgt tgacagttgt ttggcttcgt accataaata
      301 aggaaccggc aaaaacaaga agactagcgg ctaaaatcat agcatttatc tttttgtttt
      361 catacatttt ccacatgaac aacaacatga tgactgccat gactgcaccc atcatcaacg
      421 ccatgaatac acgtgtgcga ctgaagaaga tatgatcaag cgcataaaca ttcaaataca
      481 tcataccaaa catgactacc gtcgaaacac caatcatcaa caaaaacttc caatactttt
      541 tcatttaaaa caaactcctt tttcttcatt cctttcttct atcatgtcat gagcgtggag
      601 aacaatcaat taatctgcac agatggtttt tgaacaccgt ttattcggaa aaaagaactg
      661 caacaatttt tgtcgcagct cctttttttc aatagctcca gatattcaat ataaatagaa
      721 taaaattctc tattggtttc attcattcgt caagacgaaa gcatcattct ttttttgata
      781 actgaaataa atgaacaggt aaagcaaacc ggtcaataca gttaccccaa tggagttcgt
      841 gaataggata ccaaggaaaa tcaaccataa gactgctaat gcaaaaaagc tgattccttt
      901 gtcccataac gttcctttcc ttagtgtcag tacaaaggac gcagcactga taatgatcca
      961 gatcaataat actgtatagg aaagagaacc tgccagatag ccaaataatt tgtcaccgac
     1021 aaaataagaa agagccacac ctagataaag aacactggta caaaacagca cagcacgttg
     1081 cggtacttga tgcttgttta aaacagctag ttttctagag gaacctttcc gatctttcaa
     1141 gcggaagaac aaaattctcg aagaagcata tacacctgaa ttgatagacg agaacagagc
     1201 aagaacaatc acgaaattga cgatatctgc cgcaaatgga atattcattt tttcaaatac
     1261 catcacaaaa ggactaacgt tcgtgcctgc taaagtattc caaggaaaaa taatcaaaag
     1321 caaaaataaa ggaataatgt aaaaggaaat gattcttccc atgacgcctt tgattgcttt
     1381 aggaatcgca cgtttaggat catctgcttc gcttactgtg atagcaatca actcagaacc
     1441 gccgtaagaa tagataacta caagcaaaga actgatgatt cccttcatac cgtggggagt
     1501 aaaaccacca tgatcagtta attgttgaag ggtagggaaa acaccagtac ccaacatttg
     1561 ctgaccgaca agataagcag caaaaatgat caataggata atgacactga ttttagcaaa
     1621 ggccagccaa tattctgtct ctgcgaataa tcgtaccgaa taaagattga tgatagtagt
     1681 taaaacagcc aacataaaaa caaataccca agctgggatg tgggggaacc acaactgtaa
     1741 aaaggaagca gctgcaacag cttcagcaat gatattgata atccacatgg accagtagac
     1801 ccaatcggta aaatcggcag catgagcacc tagatatgga cgaatcaatc cagataatcc
     1861 gtggtgcgta tcaccaccac ttaaaacaat ttttcccaga cctttcatca cgatatataa
     1921 aattatgccg ccaatcaaaa aagcgatcaa tacagaaggg ccggcgattc caatcgcttc
     1981 gccacttcct ttaaatagac ctgcaccaat cgctccacct aaagctagca tggtgatatg
     2041 tcgggagcta agttgttttt tcaatttttt atcttccata aataacctct ttcttttaaa
     2101 ttcacaatca aaatgcatag taagaataaa tagtaagaat aaatagtaat aataataatg
     2161 actaatgata acaaattttc agataattac aactattcag aaaacttttg ggcatatttt
     2221 aatggaagaa tgatttattt catcgtattt tcatagaaat gttaaatttt tataaaaata
     2281 ataggaagcg ttttactggc tttttactat ttaaacaggc tatcatagga aaaagtgaca
     2341 gagaaagtga ggcggaacag atgaacaaaa acgacgtatt gctaattgcg aaaaataaat
     2401 cactttattt ttttccttcc atccgctctt tagatgtttg gtccggaaaa gatttactac
     2461 agtcggaatt cattaaatca gctcgacaac agttggcaaa ttatcagctg atcgtttttt
     2521 tagattatgg atttgatatg gagatggctc gacgcgtgcg tccatttacc aatgcaaaaa
     2581 tcgtgttatt tttttggaac cactttaaag cagaacacga ggcgatgctg aagcaggcac
     2641 aagatgaacc ggcaatcgat gagatttatc attttgattt tttagaagcg aaagaacttg
     2701 gactaaaaca taatagttcc ttttattcga aacatatgga tttttcttct agcgaaccaa
     2761 agacggatct attttttggt gcaacaaata acggcagaaa agaacgggca gaaaaatata
     2821 agcaggaatt tacaaaaaga ggtgttacga ccaattactt tattcttccg cttcgaggaa
     2881 atgaacaacc tggatacctt acttatgaag aatatctgaa aaaaaccggg gaatcgaggg
     2941 ggattctaga actgttgcgg gaagggcagc aaggagtgac tttgcgaacg tttgaatcta
     3001 tgtattttca aaagaaacta gtgacagata atcaagccat agctcattat cagttttatc
     3061 attctgaaaa tatttttttg cttcaagaac gtgatttaga tgaattaccg gaatttttgc
     3121 atacgccatt tcaaccaatc ccatcagaac tgttggaatt ttttgatgca gaaaattggg
     3181 caaaacgttt tttcactact gactccgcta tttatgaaca atatgaatac gatctttcct
     3241 ctgttaaaaa taaataaaag tgccaaccaa tcatagatga aaataaacaa gcgcaattct
     3301 tatggcaaca tgagaattgt gtttttcttt ttgaactttc atgggggtaa aaaaatgaga
     3361 accagctgct gatccagctg attctcatca gagagccttt tattctgcgc caaggattcc
     3421 ttcttttgca tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt
     3481 ttgtcctttt cgccaaacgg caccattgat gtagtcgatt tcagtcaaac gatggttttt
     3541 gatcaggtct tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga
     3601 agcaatatgt tggtacactt cttcttgatc taatgtgatt ccttcttttg ctgcgataga
     3661 agcaaactca gatacaatcg ttcgaaccat gccctctgcc gctttttgcg cacctaattc
     3721 agcaatatta caatccaata tcgtgcataa tccatttaat gttccgttta cacaagcttt
     3781 tcgccaaatg gaataacgaa cattatgact atagattgga ttcaattttg cttcttgaaa
     3841 gacttctaca actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat
     3901 ttctccatca cctaataatg tgacttttcc gggaccagct agaccagctg tccacatcgt
     3961 gatcccaaat aagatatttt tctttggtac atatttttcc agtacatctt catgacctaa
     4021 tccattcagt aaacacaaaa cataagtatt ctcagtaata atggattgga tcgaacgaaa
     4081 catatcatct aattgattcg cttttgtcaa ggctacgatc aaatccacgt gtttgttgct
     4141 ttcgatgatt tcttctggtg aatagattgg cagttttgca actacttctt tgccattaaa
     4201 gtcagcaatc aatccatttg tacgaatggc ttcaatgtga gcaggccagc gatcgatcaa
     4261 gacgacctca tttccgcttt gatgcaacat taatccgatt cggctgccca ttgctccggc
     4321 tccagctatt gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta
     4381 tatagaaaaa cagaagaaaa tagcattgtt ttgtttgaaa aaagtgaaaa aaagtgtctt
     4441 acttaagaag aaagtgaggg atatagatgg atattttggc ggcaatcgat tcatttaaag
     4501 gaagtgcttc ttcatttgaa ttaaatcagg cagttctaaa tggttgggaa gaccgtaaag
     4561 gaagaaaaat caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt
     4621 acgcgctcgg gggaacctgg cgtacgattg atgggatgga tctcttattt cgtcagcgaa
     4681 aaatcagtta tttattgacg aactggcaag gaaaaaatac cgcagtcatt gaatctgcac
     4741 aagtattagg attagattta cttgataaac caacggatca aaccatccga cttgcttcta
     4801 gttatgcctt gggagagctt atcaaagata cactgcttca agaagtggaa caaatcattg
     4861 tcactttagg aggaagcgga tgtagcgatg gtggtctagg attactccaa tctttgggtg
     4921 cttctttaga agggtacaca gaaggaaatc ctttgttatc tactagaaaa cttcatttgg
     4981 atcgaaggaa cgttcttgtt tctaaagtaa aagtgatcat cgctgcagac gtgaccaacc
     5041 catatacagg tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaacggata
     5101 cgacgttagc tttcttggat aaacaagctg aaaagattgc tcagcagata aaagatgttt
     5161 gggaggtgga tttagatgac atcccaggaa gcggagcagc aggcggtatt ggcggagccc
     5221 tttttttgtt aggagcgaag atggtctctg gttttgagtt ggtcagccaa atcactggat
     5281 tagaaaaaca gatcgaacaa gcggatgtca tcattacagg agaagggcgg attgatcagc
     5341 aaacaatcca cggaaaagtt ccatatggcg tagcagtgct tgcaaaaaaa tatcgaaaac
     5401 caataatcgc tatttgcgga agtagagacc gagagctgga aggactcttt gattttctcc
     5461 ccattgtctt aagcattcaa ttaggaccaa tcgatttaga ggaagcaatg gaacacaggc
     5521 aaacattaga aaaaacagaa atcttaggac agacactcag cagatttttc aacattctcc
     5581 cgaagtagtt gacaaaaaca atttctttat gctatcgtaa tttcaaatat aggacaaagt
     5641 gagggatccg tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct
     5701 tgtggagaca agggagcagt gtgcagattt tcgggattgg cttggttctt tcgatgtatg
     5761 ggtctttttg tgtgccccaa cccttgcatc ctctttagcc agttctgaaa ataggactgg
     5821 tcttttttta cgaggtgatg gaataatgtc taaaatcgaa ataaaaaatc tgacattcgg
     5881 ctatgacagc caaggcacat tattatttga acaagccaat ctaaactttg acacacaatg
     5941 gaaactagga cttatcggac gaaacggtcg aggaaagaca actttactga atatcctgca
     6001 aaacaaactc ccttatcaag ggcaagtgat ccatcagcaa gcgtttgtct atttcccgca
     6061 gcaaacaaaa gataaagagc gtttgaccta ttatgtgtta aatgagatta tggattttga
     6121 gatatgggaa attgaaagag agctccaact gatgcaaaca gatcctgaaa tcttatggag
     6181 agaattcagc acactatcag gaggagagaa gacaaaagtc ctactggcac tcttatttgt
     6241 ggatgacact catttcccgt taatcgatga accaacgaat catttggata tctctggcag
     6301 aaaacaagta gcggcttact tgaaaaagaa aaaacaagga ttcatcgtgg tgagtcatga
     6361 tcggggattt atcgatgaag tagtggacca tgttttagca atcgaaaaga gccaactgga
     6421 actttatcaa gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga
     6481 aatagctaaa aatgaaaaat tgaaaaaaga agtcagcagg ctaaagaaaa cagcagctga
     6541 aaaagcagaa tggtctcgtt cccgagaagg ggacaaaaca aagaaaaaag tcggattcat
     6601 cgatacggaa tctaggcgag tgaataaagg agcagtaggc gctgatgctg cacggacgat
     6661 gaaacgatct aaagcaatcg tgaatcggat ggaaacccag atcagtgaga aagaaaaatt
     6721 attaaaagat atcgagtata tcgatgcttt gacgatgaat agccaagtgt ctcatcataa
     6781 acggctgtta agcgtagaaa atcttcaatt agggtatgaa aatctgttat tcgagccagt
     6841 tcattttacg atcgaacctc atcagcggat ggcaatttca ggtcctaacg gcgcgggaaa
     6901 gtcatccatt atccattatc ttctggggac attcaacggc aaggttgtag gagaaaaatc
     6961 ccagcccaaa catttgacca ttagttacgt acgccaaaat tatgaagaca atcgagggac
     7021 attggcggaa ttcgcgaaga aaaaccgagt agactatcaa gcatttttga ataatctccg
     7081 aaagcttggg atggaaagag atgtttttca taataaaatc gaacagatga gtatgggaca
     7141 acggaaaaaa gtggaattgg ctaaatcttt atcccaacca gctgagctct atatatggga
     7201 tgaaccattg aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgattttgaa
     7261 cgtgaaacct gctatgttac tagtggaaca tgatcaaacc tttctagata aagtatctac
     7321 tgagattatt tctcttgaga aaatctaaac cttgtaatct caaagacaac aaggtatggt
     7381 taaggagaac tttgtcaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga
     7441 aacaacttgg aacgcacaag gattagtttg cgggcgagca gatgtgccgc tgactgaaaa
     7501 aggacagatg caggcacagg cactagcaga aaaggtagta gatttgcctg ttccaatcac
     7561 gaaaatcatc cattcccctc ttcaacgagc aagagataca gcacaagcag tagttgatcg
     7621 tctcaatttg ccgatgaccg ctgatgagcg attggtagaa atggattttg gggattatga
     7681 cggactgcca agcaaagatg aaaactttca aaaagcgcgt ttagcgtttg ctgtacgttt
     7741 cccaaatgga gagtcggtct tagatgtgta cgcacggatc gttcctttat tgaaagaatg
     7801 catggaagac gaagaaaatg tctacttgtt agtctgtcat aatgccttga taagagtgat
     7861 caatgcttat tttcatccaa tgcctaatga agggttcttt acattcatgg tagacaatac
     7921 agaattaatt tcttatgagt aattagactt ttgtgttatt taaataaaat gtttcaaggc
     7981 actgcttttg cttagcagtg ccttttttgt ggctgtgtca attcttttgg cattataaat
     8041 ccaattttta gaaataaaat ttaattattt taacaaaagt attgaaattt tgtttcttta
     8101 gatatatact ctagtcatag aaatgaagac ggatacagaa aaagagggat aatatgtttg
     8161 gcttttcaat atttatgaat gattctttgt cagaagagaa gaaacagtat atccgccaaa
     8221 tggcatccaa tggctttgtc ggtattttca cttccatgca tataccggaa gatgatgttt
     8281 cggcttatca aaatcgattg atcgaactag gaagcgaagc gaaaaagaat aaactagagt
     8341 tgatggtcga tatttcagga gaggcattga aacgagctgg cttttcatta gaagatctaa
     8401 cacccttgaa agcaattggt gtaacagggt taagaatgga ttatcatatt tctaatcagc
     8461 agatcgccga ctggtcacat caattgaaaa tcagtttgaa tgccagcacg atcacgccta
     8521 atgatatcga tgagttgaaa gaagcagcgg ctgatttctc acagattgaa gcttggcata
     8581 attattatcc acgtcttgaa acagggttgg acaaagaatg gtatcaggaa aaaaatcaat
     8641 ggctcaaaac tcaaggattc cttgtacaag gctttgtacc aggagataca gagttgagag
     8701 gtccactgta tcaaggatta ccaactttgg aagaacatcg agggatccat cctctggcag
     8761 gtgctcttga tctattagca agtaacacgg atattgttta tatcggagat gcaggtctgt
     8821 cagaacacgt tcaggagcaa tttgcttctt tccaaaaaga acagacagtc ttgctccata
     8881 cggaacctgt agatgaagtt ttttacgaat atatattagg aaaacatacg aatcggcaag
     8941 atgatgcaag agatgtcata cgaagcgcag atgcgcgttt tcgagagatt ccgccaatcc
     9001 cagtaagaaa tacagctaag cgtatgaaag gatctattac tttagataac gaaaagtatt
     9061 tgcgctatat gggtgagatc caattaacta aatatgattt gccagcggat gaaaaagtga
     9121 atgtagtagc caaagtcatc aaagaagaac taccgctgat caaccaaatc aaagctggta
     9181 tgaactatca atttataaga aaagaaggaa gataaaaatg agcaaaatca atttagagaa
     9241 cctaacaacg gaacgcagaa accaagaaac ttttggatta gatgaaatga gtatttctca
     9301 agcagtccaa ctcatgaaca aagaagatca gaaagtggcc gctgctgttg aaaaagaact
     9361 gccaagtatc gagccagtga tcgccaacac gattgaatcc tttaaaaaag gtggtcgctt
     9421 gatttatatg ggagctggaa cgagtggtag acttggtgta ttagatgctg ctgaatgtgt
     9481 accgacattc ggtgtagaac cggaaatggt cataggccta attgctggtg gagaagaagc
     9541 aatgactgta gccgtcgaag gagccgaaga ttcttatgaa ttagggcaag aagatctaat
     9601 caagctgaat ttaacaaaaa atgatatagt tattggtatc gcagctagcg gtcgtacacc
     9661 atatgtgatt ggtggattag attacgcaaa atcgattggt gctgttacag gaacgatttc
     9721 ttgcaataaa caagcagaaa tcagcgagca tgcggatttc ccaatcgaag tcgatgcagg
     9781 accagaattt ttgacaggct ctactcgatt gaagtcagga acagcacaaa aactgatttt
     9841 gaatatgatt tctactatca gtatgatcgg tatcggtaaa gtattcaata acttgatggt
     9901 cgacgtcaaa ccaacaaatg aaaaactaat tgaacgctca aaacgaatca tcatgcaagc
     9961 gacagaagct gactacgaaa cagctgaaaa gtactttgag gaagcagatc aaaatgtcaa
    10021 actggctatc gtcatgattt tgacaaatag tgataaagag gcagctcaag caaaattagc
    10081 tgaagcaaac ggttttgtaa aaggaacctt atgaggggga aaagaccatg gcaaaaaacg
    10141 aattgacttt ggaagaactg gcaaaacaaa tttatcaagg agcaggcggt atgggcaatg
    10201 ttgaaagcat tgtccactgc atgactcgtg tacgtatgaa ggtcatcaat gatgatcttg
    10261 taaatgtctc ggaattaaaa gcgattccag gagtacttgg cgtagtagag gatgaacagc
    10321 tccaagtcat catcggacct gggaaagtga acaaagtagc gcaggaaatg gttgacttag
    10381 caggcgtgaa attaggagaa aaacttcctt ctgctagtgc aactacagca agttcttctg
    10441 catctggaaa agaccgtgta aacgaacggg cacaagaaat gaaagcggca caaaaatcga
    10501 aacaaaaacc ctctaaaatc aaatcggtat taaaagacat ctctaatatc tttgtaccaa
    10561 tgatccctgc atttgtcggc actgggatcg tggcagggat tgccgcagtt ttagcaaact
    10621 tagtcacagc tggaacacta gacgcaggaa catggcaaca atatatcgat gtgatgaaca
    10681 tcttgaaaaa cgggatgttt agctatctag ttatctatac aggtatcaat gctgcacaag
    10741 tttttggtgc aacgccaacg cttggtggag ttatcggggc tgttgtgatg ctgacaggga
    10801 tgaatccaga agcaccactg aaaaacttgt ttaccggtga agctcttgca actggacaag
    10861 gcgggatctt aggtgttatc ttcgcagttt ggttattgtc aatcgttgag aaaaaactgc
    10921 ataaagtagt acctgatgcg gtagatatca tcgttacgcc aactctttcc ctgattgcca
    10981 tcggtctgat cgaaattttc ttcatcatgc ctttagcagg gttcatttct gacggcatgg
    11041 tcggtgggat caactgggta cttggtgttg gaggagcatt tgccggcttc gttctaggta
    11101 cattattctt gccaatggtc atgttcggac tacatcagat cttgacgcca atccatgtac
    11161 aaatgattga tgaaactggt cgtaccttat tgcttccaat ccttgcgatg gccggagcag
    11221 gacaagtggg tgcagcattg gcattatgga tccgctgcaa aaaagacaaa gaattaacag
    11281 aaatgatcaa aggggcttta ccagtcggaa tcttaggaat cggcgaacca ttgatttacg
    11341 gagtaacatt acctctagga cgtccattta ttactgcttg tatcggtgga ggtatcggtg
    11401 gggcagtgat cggaatgatc ggaaatgtcg gagcaatcgc tattggacct tcaggagccg
    11461 ctttgattcc attgatctct gatggtaaat ggttaggcta tatccttggt ttattggctg
    11521 cttacgctgg tggcttcgtt gctacattct tcttcggtat tcctaaagac cgtttagaaa
    11581 aagaagaact agcgaccgaa acagccacag taaatgaagt acctgaaaaa gcagtacctc
    11641 aagcttcagc tgaaagtgtg actatcttat catcagttgc tgacggaaca gttgtttctt
    11701 tagataaagc aagtgaccca gtttttgcac aaaaaatgat gggtgaaggt tactttgtag
    11761 aaccagaaaa cggacatatc tattccccgg ttactggagt aataagttct gttttcccaa
    11821 caaaacatgc tatcggcatt acgacaccaa atggcttaga aatcttgctt cacatgggca
    11881 tcaacacagt tgacttaggc ggtacgccat tcgatgtgaa agtaacagaa ggacagcaag
    11941 tgacacctga tacgcttgta gcagaagctg acttagaagc aatcaaagca gcagacaaag
    12001 aaacctccat gatcgtcttg gtaaccaata tggatcgtgt aaaaaacttt gtcttggaaa
    12061 aaacaggtaa agcgaaagca aaagcacctg tgatggatgt caaagcttaa taagaataga
    12121 aacaatagag aacataaaaa gaagaagccg aaatttattt ttcagcttct tcttttgtgt
    12181 tatttatttt tttctgccaa aatttgataa acgcgtgtca catcagatgg tgttccccgt
    12241 aattcataat ctgccaagaa aggaaagccg aatctttgtg cgtattgttt ggctgtcaga
    12301 caatattgat tgttgaagtt tttattaccg ctaccgacta caccaaggca aagtttatga
    12361 ttgtcttcgt attccagata ttcgcgcatc gtttcggtca agatttctgt gtcaccgttg
    12421 tctaacccat tcccgccgtc taaataagta ggaacgaaag taaaaaatgg ttctgtttct
    12481 ttcgtaaaat cactattttc atggatttct tttaaagtaa cttcaggatt gacaggatct
    12541 tctgcatgca ttttttcagc atattctgct agatgtttgg caaaagcacg cgtatttcct
    12601 gaaatcgata tatataaaat gttcatggat catcccccaa ttctttccct ttagtatagc
    12661 atctttttaa gtttttttgg tggtgtaatt tggaaaggga ctaggcgctt tgcttgtata
    12721 atgagaaaaa agtcggtaga attatatttc tattaaagtt tttattaatt aagtaaaaat
    12781 aaaaaaggtt tgttatactt tttgataaaa gcggttttac tttggaggat gcttacatgg
    12841 atacagagca acagaaaaaa ggaattggtt tgattccact tgctgcctta gtgattggtt
    12901 cagcgattgg aggtggcgta tttggtatta tgacggacat ctccggatcg gctggtggcc
    12961 cagctatctt cagctgggta ctcgtaggaa cagcaatgtt gatgctctcc ttatcgatca
    13021 ataatatcaa taaaaaacgt ccagatttaa aaggcgggat ctttagttac gcagaagaag
    13081 gttttggccg tttcgctggt tttatcagcg gttggggtta ctggctcaca tgctggttag
    13141 gaaacgtggc gttcgcaaca ttgttgatga gtgcattagg ttatttcttc cccgtattcg
    13201 aaggtggtca aaatgtggca tcgatcgtga tgagtacgat cttcttatgg ggatatgcat
    13261 ggctagtgaa tcgtggagtt gaaaatgcta gctttgtcaa tgctatcgtc acattttgta
    13321 aattagtgcc attattttta tttattgtag tagctatcag caccttttcg atccaacaat
    13381 tcattaataa cttttctagc gatatcatat tgaatgcgaa tgggcagccg atcccgtttt
    13441 ctagtcaagt attgagttgc atcatggtga tgctctgggt attcgttggt attgaaggag
    13501 cttctgtcgt aggttcacga gcaaaaaaac aatcggatgt tgggaaagca acgattctag
    13561 gaatattcgg tttgatcatt atttacgtct tggtttccat gcttccatat ggcacaatga
    13621 cgatgaatca gctgcaaacg atcaaagcgc aacctgctat gggatatgta tttgaaatga
    13681 tggttggtaa atggggggcg gtcgtgatca acggcggttt gatcatttct ttagttgggg
    13741 tttggctctc atggacaatc ttgccgattg aaacaatggg gaatatggct gaggacggac
    13801 ttttgcctaa agcatgggga aaactcaaca aaaatggggc accaacttat gctatcgtat
    13861 tgacgacgtt atgtacgaat gtctttttac tttcattatt attcactgac agtgcatata
    13921 actttgctta tacacttggt acagcagcga ttttcttcac gtggcttttc ttagggctgt
    13981 accaaatgaa gctttcttat cagcggaaag agtgggtcca atttttagta gggtttttag
    14041 caagtgcttt tcaagtatgg gccatgctag ttgtagcctt taatgaagtg atgcttgttc
    14101 ttgttctttt cttaccaggt atttattttt acctcaaagc acgtaaagaa caaaacgaac
    14161 ctgtacaaca tatccactta gataagattt tacttatcgg tgtgacgatg gtcggagtaa
    14221 tcgcaatggt tttatttgcc actgggatgc ttcacgtata gaagtataaa gagaggctgt
    14281 gaagcctgtg gtttattcaa aaaagaagcg gtgacaacat tcgtgtcatc gcttcttttt
    14341 ttgaataaat ggtgttcaag aagtagcttc ttctaaaaat aagccgaaat ttcttgaaac
    14401 tggccacttc tgtcacaact tctttgttaa tgaaccatca tacatttttt cgcttgaata
    14461 cgaggtatcc caatgctaag aacaaagcaa tgtaagctaa attgccaaac agcatttgat
    14521 tagtagaaag atgagtcaat tgcttcataa tctcttcgtt gccaatttgg ttttgcagat
    14581 tcagcatact gattggattc catttgatcc actcccattt ttgaatgagt gcgatgagga
    14641 taccagatat gattgatgaa gcaaaataaa agacgatccc tgctgagatg gaggcaccgg
    14701 aactattgat aaaacaagca atcatcaaca ctaaacttaa aattagccat aaaccgatat
    14761 aactacccaa agtataagtg aataagcttt ggatcagtgt ctgaccagta gaaatcttct
    14821 ccgtaaagga aatcgaaggg aaaaggatca gtttcatcag cacggtgaca ataatagcta
    14881 aaaggtataa ataaatagaa taaataacta atgtgatcca tttacttact aatatttctc
    14941 ctcgagaata ctttcgataa aggagatttt tcaatgtacc atattgtgat tccattgaaa
    15001 tgatcgtact tgcagcagca atcatgataa agacaatcca agatgtggca ctgaaaagct
    15061 gagcagtcat ttcaactgga tcaatgatcg tcgtgtattt tttggctaga agtgctgttc
    15121 ctatgagcaa agcaactaat agaacagata aaacagcagt tgactttttc ttgatcaatt
    15181 taaataattc ttgttttata agcaacgtca tttttcttct tcccccttta ctgaatccag
    15241 aatttccaat agggaagatt ccaaatcatt cgtcagatgc tggacatctg tcacatggac
    15301 attttctgca gacaataact ggataacagt tcctaataac tcttcgtttt tttttagaag
    15361 cttgatttta tcaggatctt ccaagggata tccagcgtct gtcaagatcg ttcgagcagc
    15421 ttgatcattt gtcgtagaga taacgatgaa atcttgcgct gtttggttca attcagccat
    15481 tgtacattgt ttgatgattt ttccttgatt gatcaggatc agctcatcga ccattttttc
    15541 aagctcgctg agtaagtgac tggagatcaa gaaagaggtg ccctgagtag ccaagtcggt
    15601 aatgattttt cgcacatctc ttgttgcttg tggatccaaa ccgttcatcg gctcatctaa
    15661 aataacgata gacggatggt tcagtaaggc aagagcaatt cccaattttt gtttcattcc
    15721 cagcgagtag gatttcgctt ttttgtgaat gtatttttcc atcttgagct gtttcacgat
    15781 agtgtcgata gcagatacat cgtttgtttc agagaataac ttcagatgat cataacctgt
    15841 taagaatgga tagatacccg gatattcgat caatgctcct acttgttcta atcctttatg
    15901 actagaggga gaaatctcat tttcaccaat acggatcgtt ccttctgagt aatggatcag
    15961 tcctaaaata gctttcatga tcgttgtttt tccagcgcca ttaggaccta ctaatccaac
    16021 gattttgcca ggagataagc taaaactgac atcgctgagg gcttgtttgt gaccaaagtt
    16081 cttggataat tcttggaccg aaagactttt caaaaatatt cactcctttt ctatagatag
    16141 tacaagcata cacctgatga gtagagaagt cgctaggtca ttagtcttat tttcttgttt
    16201 tttcatagaa agaggaatat caaataaaaa gccccgcttt ttctgatcag tccttgtctg
    16261 cttgtctaag tatctagtga ccgctagtga ttttgatgcc aatgatgctg atgagcagca
    16321 acccgacaaa gaaccaagtg gaaagattca gcttatcatg aaacaagacc acaccaataa
    16381 tgaccgaacc aactgcgcca atccctgtcc aaataggata agagagactc ataggcaaac
    16441 ttttgattgc ctttgacaaa aagtaaaaac tagcaatcat tccaatcact gtgtaaaaag
    16501 aataattgat tttagaaaaa ccatcactcc atttcatcat cgttgaccag aatacttcca
    16561 aaattcctgc tatgattaat tccatccatg ccatacatac gttcctcctt caatataaaa
    16621 aatacacaaa aagaggagaa tcatcccttc aaagacctaa tggaatgatc atcctctttt
    16681 ttactacccg gtggcagatc gtatatcttt ttctgtagta tagcacacct atccagatat
    16741 cggcaatctc atacttttta gtaaagtgta acaagcattg acggatatat cgttagcaga
    16801 aaagaagatg aatgctttgc aatttcatag aaaggagttg ttatttatta atcatttaaa
    16861 aaaacagtaa ctagacctta tttttatata ttagcaggca ataaattaaa aaaagcttta
    16921 tcttacaata agtaaggtga attatataat aaaaaaataa cgaaaaatat ttaaaaatag
    16981 tgtctatttc gtgagaaaac aactatattt tttatgtgtt ttgctttata attaaaaaaa
    17041 tattgtcatt ttatggagga aaatatatgg aaaattatct tagcctttta ggcgtcttga
    17101 ttgttattct cgggtttgca tttaaattag actcgatatt gatcgtaatg gttgctttag
    17161 ttgttacagc tttgactggc ggtcttggca ttcaaggaat gttagaactt ttaggtacaa
    17221 gttttgtaaa caatcgcggg atggcgattt ttatcatcat tatgttggca acaggaacgc
    17281 ttgaaagaaa tggtctgaaa gaatcagcgg cttccttgat caagcgattc aagaaagtat
    17341 ctgctggtat gattgtagat atttatggga tctttcgaat gatctttgcg gcttttaacg
    17401 tgagttttgg tggagttgct ggatttgttc gtccaatcat tttaccgatg gcattgggga
    17461 ccatcgaatc aaaagggtta gaagtccatc ctaagcatga agaagaacta aaaggtatgg
    17521 cttcagctat ggaaaatgtc tgctggttct ttggccaagt actattcatc ggaggagcag
    17581 gggcgttgct agtccaatca acactgaaag atctaggata tgacgtaaca ttgggacagc
    17641 ttgctttagt ggaagttcca gtggctatca cggctttagt tgtggcaagt gtctacttct
    17701 atcttaaaga aaagaaatta gcgaagaaat attatccagg aaaggggcaa taagatggac
    17761 ttttttacaa atcctgatat tttattaggc gataaattac tggagatcct ttatatcgtg
    17821 atgggactcg tattgattta cactggagta agaaatttaa cagataaaac caatcctcat
    17881 cgttatgggt cagccttttt ctggacggtc ttaggggtag ttattgcagg aggaagatgg
    17941 cttccggcaa tcgtgaacgg tggcttgatc tttgcgatga ccataccagc aattgctaag
    18001 aaagtcagca aaggagaaag ccggcttcca tcaaaagaat atatggaaaa aatgtcagac
    18061 aaactaggaa tgaaaatttt tattccagct ttgagtatcg gtgtctttgc gatcttgttt
    18121 gctctattta ccaatttagg tgctttagtc ggcgtgggcg tcggtgtttt tgcagccatg
    18181 ctaatcttga tgttcttttc tcgagataat cgaccaagta catttttaga tgatgcagca
    18241 gatatgctgg gcacagtagg gccgttaagc atgttgccaa tgcttttagc ttctctaggt
    18301 gcggtattta caagcgctgg agttgggaca gtgatttcca atgcagtagg tacgatcgtt
    18361 ccagaaggaa atgtgaacat cggcatcatc atttacgctc ttggcatggt gatatttacg
    18421 gtaatcatgg ggaatgcatt tgcggccatc accgtgatga cggttgggat cggtgcacca
    18481 ttcgtattta gtcatggagc gaatccagcg ttaataggaa tggttgcatt gacttgcggt
    18541 ttttgtggga ccctgctgac accgatggct gctaacttca atatcgtgcc tgtagcgatg
    18601 ctggagatga aagacaaata cggagtgatc aaaaaccagt tgtttattgc gttatttatg
    18661 ctagttttcc aaattgctta tatgattcta tttaaataat agaagagagg ggttgtgaca
    18721 gaataattgt cgcaacctct tctaacattg tagtggaaca ctattttttt ataagaatat
    18781 attaagtttg atctgttatg ttatttaaac tattgtttcc tttatttacg ctgttcaagg
    18841 aaaatggtat gataaaagat aaccatatgt taaatcaatc ggacggagga acaacagatg
    18901 aaagtactag taacaggttt tgatccattt ggtggggaca aagtgaatcc agcctatgaa
    18961 gcagtaaaaa aaatgccaga tgaaatcagc ggtgctgaaa tcatcaaagt ggaagtaccg
    19021 accgtattcg aaaaaagcag tcaagtagtc aaagaagcca tccaacagca ccaaccagat
    19081 gtcgtgatct gtgtcggaca agcaggtggg cggtcagcag tctcgttcga acgtgtcgca
    19141 atcaatctag cagaagcaag aatccctgat aatgaaggaa atcagccatt cgatacggct
    19201 ttagaagaaa acggtccagc cgcttacttt acctcattgc caatcaaagc aatgacaaaa
    19261 aatgtacaag atcatggtct accagcgtac atctcttata cagcaggaac atttgtctgc
    19321 aatgatatca tgtatcgttt gcttcatttg atcgaaacac aattcccggc aattcgaggt
    19381 gggttcatcc acgtgccatt ctcacccgat caagtgatcg atcgtccagt gggtacgcct
    19441 tctatgtctt tagaagacat tgcttcttct ttgacttatg cagttgaagc agcagtagaa
    19501 aataaagaag atatttccgg aaatgccgga acaactcact aatttagcaa gaaacactgg
    19561 ctggttgcta acgttatgtt agtagccagc tttttgtaat tagaaaggaa agaaacagcc
    19621 gtggaagaat ggcaatccgt ctttgaagaa tggtttccaa aagaaatcag caaaagctat
    19681 cccatcaaaa tttctaaaca atacacaagc agtcaacgtt gggagatcta tgcaaaatta
    19741 acgaaaaaac agcgggaact agtcgataag caccgccgat atctaatcag ctctcgtttt
    19801 atggaagaac attatttagc tgcaacagat tgggtgtttt ctgacttcaa gatcaatccg
    19861 ttttttcgaa caaaacgaag ccagcaaaaa ttgtattgtg agtgtggtag agaattaaaa
    19921 gtgcaataca tcgttaaatc gccaaaaacc ggaaagatcc taaaactagg catcaaccac
    19981 tttgccgatc acctgcatgt ctctccgaca gtggcagctt cgatccatca gggaatgaca
    20041 aaagttgatc tggccttaga cgaattatta tggcttaagc agaagaatat cgattttcct
    20101 gaaggactat ggcaaaaata ctgttttgtc ttgtaccaaa atcgtcggat gaaacagcca
    20161 tatttaccgg atataaaatt agctcagcgg ctcgcagaat ttcgccaagt agaaatgccg
    20221 atttacatag cggattatca agcattggaa aatgaaatca agaaaataag tgaacacatc
    20281 aatgggcagt caaaaaagcg acagataaaa aaagaactat ttgacgactt tgcagaagaa
    20341 ttagtaaagg atgtagaaga attcttgatc aactatcgcg catttttacg taaagattgg
    20401 caatccatcg tatatgaaga agtgccagta catcctaatg cttattttga aacatttatt
    20461 tccgtgttga gaaagacaaa acgtcaacga acaccagaag tcactgctca gatggaatat
    20521 tttgcgaaaa accaacgatt catccaacca aaaatctatc tatttatttg gaagcaatat
    20581 tgtcgctatg gttttacaga agggttcttc gacagcattc ctcggatagt cagaaatggt
    20641 tttttaaaag tattgcgtaa agaacgagaa gctatacaat ctgctgataa gaaagaccgt
    20701 acagtctcaa aagaaaaatg gcaactagta gtgaaagata tccaatctgg aaatgtgcaa
    20761 gagacaatcg acaaatggaa aggaaaacat tatcgtttta ctgaagctca gaaacaagcg
    20821 ttggaatatt atcagaagtt agaagaatca ctgcgtttca atgatgaggc aagaaagtat
    20881 ctgaaggaat tactataaaa aatagaggct gggacagaag cgtttaactc caagaaataa
    20941 gaa
//
LOCUS       DAFELK010000187        13213 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.074, whole genome shotgun sequence.
ACCESSION   DAFELK010000187
VERSION     DAFELK010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.074"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(204..2162)
                     /locus_tag="LP433_003092"
     CDS             complement(204..2162)
                     /locus_tag="LP433_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2007151.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="LP433_003093"
     CDS             complement(2159..3031)
                     /locus_tag="LP433_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2007152.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="LP433_003094"
     CDS             complement(3373..4245)
                     /locus_tag="LP433_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2007153.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="LP433_003095"
     CDS             4373..4942
                     /locus_tag="LP433_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL2007154.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="LP433_003096"
     CDS             5009..5746
                     /locus_tag="LP433_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2007155.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="LP433_003097"
     CDS             5977..7245
                     /locus_tag="LP433_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL2007156.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="LP433_003098"
     CDS             7732..8196
                     /locus_tag="LP433_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2007157.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="LP433_003099"
     CDS             8180..8809
                     /locus_tag="LP433_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL2007158.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="LP433_003100"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="LP433_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL2007159.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="LP433_003101"
     CDS             10688..11134
                     /locus_tag="LP433_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL2007160.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="LP433_003102"
     CDS             complement(11333..11848)
                     /locus_tag="LP433_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2007161.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="LP433_003103"
     CDS             11965..13167
                     /locus_tag="LP433_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2007162.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DAFELK010000188         9274 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.083, whole genome shotgun sequence.
ACCESSION   DAFELK010000188
VERSION     DAFELK010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.083"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            215..1126
                     /locus_tag="LP433_003104"
     CDS             215..1126
                     /locus_tag="LP433_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBL2007163.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1279..1764
                     /gene="vanZ"
                     /locus_tag="LP433_003105"
     CDS             1279..1764
                     /gene="vanZ"
                     /locus_tag="LP433_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL2007164.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(2051..2380)
                     /locus_tag="LP433_003106"
     CDS             complement(2051..2380)
                     /locus_tag="LP433_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2007165.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            2685..3014
                     /locus_tag="LP433_003107"
     CDS             2685..3014
                     /locus_tag="LP433_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2007166.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            3004..3291
                     /locus_tag="LP433_003108"
     CDS             3004..3291
                     /locus_tag="LP433_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2007167.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(3570..4133)
                     /locus_tag="LP433_003109"
     CDS             complement(3570..4133)
                     /locus_tag="LP433_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2007168.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(4326..4898)
                     /locus_tag="LP433_003110"
     CDS             complement(4326..4898)
                     /locus_tag="LP433_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HBL2007169.1"
                     /translation="MNKAIFWDLLGTLGGDSRTLINQNFNFFKDTIPALKKAAQSHYL
                     NIIITNQSHISHGRITMAEYTDALESLINELEKNDIQITDVYTCPHARKDNCDCKKPQ
                     PTFVNEALKKYDLNPSKCFVVGDSGKNDMMLAKNAGINSVLLLTGEGIDSLTKYRHLW
                     SETKPTFIAENSLDAINKIHMYADGDSSDS"
     gene            5686..6261
                     /locus_tag="LP433_003111"
     CDS             5686..6261
                     /locus_tag="LP433_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007170.1"
                     /translation="MKNKFKYLFTILALLPITTSTLITPTIAKASEKQEDSVSYEIVK
                     NDLYIQFEEELAELIASNQSTVSVPDLFSTQSVLSTSSQDNSISEEQFFSLVEKYDGA
                     ELTAVVNSQDAFTTKFVNGGVNSYATSYRGLNALRSELKYNAGALKVGGTLVGTAGGL
                     LGVLLGMVTGDYLSGHCDDAAAGVSAFIQAG"
     gene            complement(6444..7196)
                     /gene="istB"
                     /locus_tag="LP433_003112"
     CDS             complement(6444..7196)
                     /gene="istB"
                     /locus_tag="LP433_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBL2007171.1"
                     /translation="MMLNEQTEVKLAELKLSGMLESYREQMTNKEYQSMSFEDRFNLM
                     VDLEHSRRKNNKLQRLIKSANFRNASASIEDIEYHPDRNLDKNLILKLASGTYLEEHH
                     NIILMGASGNGKTYIANAFGIQACRQYYNVKYIRLPELLDELTISKNQADGSFRKIIN
                     RYKKVQLLIIDEWLLTNLSLENSTFLLEIIESRLKTASTIFCSQFHPEGWHEKLGNPQ
                     IADAILDRIIHDSYQILVDGKVSMRERYGIRN"
     gene            complement(7196..8737)
                     /gene="istA"
                     /locus_tag="LP433_003113"
     CDS             complement(7196..8737)
                     /gene="istA"
                     /locus_tag="LP433_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003680854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL2007172.1"
                     /translation="MFRYRRILEMHSEGISIRSIAASTGNSRQKITEVIRKAEEKGIA
                     RALSEEMTDQWLGEFLFPEKQLEANGRHLPDFDKIHKELAKPNVTLTLLHQEYAVECR
                     MSGKIPYAYRTFCDYYNAFARKHKATMRIRRKPGEIMEVDWAGSPAYVIDRDTGEKVK
                     AYVFVATLPCSQLSYAEAFLTMKSVAWITAHNHAFEYFGGSTDIIVPDNLKTGVKKNE
                     GIDVILNESYRELGEHYGSIILPARVSTPKDKPSVEGSVGVISTWIIAALRNTHCFTI
                     EDLNREIRMKLNEFNERPFTKKPGSRIRAFEEEEKFALNPLPLAPYKMSVWKKAKVQL
                     NYHVSVESMFYSVPYEYIQQNIDIRMTENLIELYFNSMRIATHKRLYGKFGQYSTVRD
                     HMPDNHKMYVDHTPESSMEWAETIGSSTVKVVQHLLDRYQNEKQALKSIMSLKSFGKK
                     YSKNEIETACSTALNLASLPSVKIIQTILKGNKQKRATSQSHIEDTNIEKHGFTRGAS
                     YFGGK"
BASE COUNT         2988 a         1542 c         1660 g         3084 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccgta tcacttatga aaattcatct
       61 acattggtga taatagtaaa tccagtaggg cgaaataatt gactgtaatt tacggggcaa
      121 aacggcacaa tctcaaacga gattgtgccg tttaagggga agattctaga aatatttcat
      181 acttccaact atatagttaa ggaggagact gaaaatgaag aagttgtttt ttttattgtt
      241 attgttattc ttaatatact taggttatga ctacgttaat gaagcactgt tttctcagga
      301 aaaagtcgaa tttcaaaatt atgatcaaaa tcccaaagaa catttagaaa atagtgggac
      361 ttctgaaaat acccaagaga aaacaattac agaagaacag gtttatcaag gaaatctgct
      421 attaatcaat agtaaatatc ctgttcgcca agaaagtgtg aagtcagata tcgtgaattt
      481 atctaaacat gacgaattaa taaatggata cgggttgctt gatagtaata tttatatgtc
      541 aaaagaaata gcacaaaaat tttcagagat ggtcaatgat gctgtaaagg gtggcgttag
      601 tcattttatt attaatagtg gctatcgaga ctttgatgag caaagtgtgc tttaccaaga
      661 aatgggggct gagtatgcct taccagcagg ttatagtgag cataattcag gtttatcact
      721 agatgtagga tcaagcttga cgaaaatgga acgagcccct gaaggaaagt ggatagaaga
      781 aaatgcttgg aaatacgggt tcattttacg ttatccagag gacaaaacag agttaacagg
      841 aattcaatat gaaccatggc atattcgcta tgttggttta ccacatagtg cgattatgaa
      901 agaaaagaat ttcgttctcg aggaatatat ggattaccta aaagaagaaa aaaccatttc
      961 tgttagtgta aatggggaaa aatatgagat cttttattat cctgttacta aaaataccac
     1021 cattcatgtg ccgactaatc ttcgttatga gatatcagga aacaatatag acggtgtaat
     1081 tgtgacagtg tttcccggat caacacatac taattcaagg aggtaaggat ggcggaatga
     1141 aaccaacgaa attaatgaac agcattattg tactagcact tttggggtaa cgttagcttt
     1201 ttaatttaaa acccacgtta actaggacat tgctatacta atgatacaac ttaaacaaaa
     1261 gaattagagg aaattatatt gggaaaaata ttatctagag gattgctagc tttatattta
     1321 gtgacactaa tctggttagt gttattcaaa ttacaataca atattttatc agtatttaat
     1381 tatcatcaaa gaagtcttaa cttgactcca tttactgcta ctgggaattt cagagagatg
     1441 atagataatg ttataatctt tattccattt ggcttgcttt tgaatgtcaa ttttaaagaa
     1501 atcggatttt tacctaagtt tgcttttgta ctggttttaa gtcttacttt tgaaataatt
     1561 caatttatct tcgctattgg agcgacagac ataacagatg taattacaaa tactgttgga
     1621 ggctttcttg gactgaaatt atatggttta agcaataagc atatgaatca aaaaaaatta
     1681 gacagagtta ttatttttgt aggtatactt ttgctcgtat tattgctcgt ttaccgtacc
     1741 catttaagaa taaattacgt gtaagatgtc taaatcaagc aatctgatct ttcatacaca
     1801 taaagatatt gaatgaattg gattagatgg aaaacgggat gtggggaaac tcgcccgtag
     1861 gtgtgaagtg aggggaaaac cggtgataaa gtaaaaagct tacctaacac tatagtaaca
     1921 aagaaagccc aattatcaat tttagtgctg aggaattggt ctctttaata aatttcctta
     1981 acgttgtaaa tccgcatttt cctgacggta cccccaaact aagatttcat agatagattt
     2041 tctgataact ttaaaaaaca cgaatagcgg aaaggatgtc ttcattcgct aaagagtaat
     2101 aaactacttt tccatcttga cgtgattttg ccattccatg tttttttaaa aaacgtaaat
     2161 ggtgtgacgt tgtagcgaca ctagcagtaa gtatttctgc taaatcacag acgcacattt
     2221 ccttataggt ttctaaagca tagaaaattt taattctaga aaaatcgctg aaacatttcc
     2281 ctaacacaag taagtttgaa aaatcttttt gatccaattt attttttatt ccatttactt
     2341 tttctttatg tacgacagtc acttggcaaa cttttttcat tcatctcacc tcacattcaa
     2401 acgattattt gaatgaagta tacctatttg atcactcttt tgtcaatcta ccttaattcc
     2461 aatacactat tataagcaat ttcatgtatt gaagtaaact tacttgcaag tgcgtttttg
     2521 attccaagtt aaaaacatat tattattcta cataatttcc taatcaaata aaactccttt
     2581 gaaaattgtt ctaaaggagt tttattattt tgtatttcta ctaaaaatag cgtacaatgt
     2641 aattactaag taattacgaa atgtaaaata atggaggaaa taatatgatt acaaaaacaa
     2701 gaaaacaagg aaattctatt atgttaacgg tccctaaaga attcgatgtg cccaatggtg
     2761 ttgaagtaga agctaagctt gtagagaatg gtatccttta tgagtttgta gagcctaaaa
     2821 aagaattttt tgattttagt gaagatattt tggctgatat tctttcagaa ggttatagca
     2881 aacaagagat cttaaaagaa tttagaaata gaaaaaatgc gttaacttct gcatttaaat
     2941 ctattgctga agatactgtt gcaaattcta aaccgatgac aaaagaggag ttggcagcag
     3001 aaattggctt atgagattct accttctaaa cacgtaataa agtatctaaa aaaattaaaa
     3061 gagaaaacat taaaagaaca atttttaacg ataatttatg atgagatagc agttcgtcct
     3121 cattcgggag aacaaaaaac gggtgattta tcaggaattt gggctattgg attcaagtat
     3181 gcaggtacga catatcgcgt tgcatatgaa attaaagata atgcagtgat acctatctta
     3241 ctatgtggaa cgcatgaaaa tttttatgaa caattaaaaa agattaggta agaacccaat
     3301 gtttcaactt gagaggatag acgacacttt aaaagataat ttttaacagc tgagagttgt
     3361 aataccctat aattttaaac cactaaccta tatatttatg aaaaatagaa aaaattaaaa
     3421 cgcattttaa gcctctttca aattaaaagc ttcatcctta tgcacaaaga gggcttaaaa
     3481 tgcgttattt tatattgttt tttagtaata ataaaaaaat cactctaatt ctcccataaa
     3541 tattatagat tcctaaagat taaaatagat tattccctat tgtcttttaa gtagcggtag
     3601 agtgttgcct tgctaatacc agtcatttcc gtaatttctt ttacgctata aacctgactt
     3661 ttatacaatt ttactgctcg atcaacatct ttctggttca ctcgtggacg gccaccttta
     3721 cgacctctcg cacgtgcact tttcaaacct tctttggtac gttcaacaat taaatcacgt
     3781 tcgaactgac taaatgcttg gaagacagtc atcattaagc gtccgtgagg cgtgctggta
     3841 tcgaagtttt ctttcaagct caccagctta acatggtgtt cttcaaaata ggtaacaagg
     3901 tcaatcaaat cctttgtact acgacccaat cgagaaaaac tttctacaat taccgtatct
     3961 cccggacgaa ttttatcttt taaacgattt agttggggac gaaccgcttt ggttcccgtc
     4021 attttctcag ttaggatttc attacaattt tgttcattga gtaagtctaa ttgacgattt
     4081 agttcttgtg aacgtgtact cactcgggca taaccataaa tgtatccact catgcttttc
     4141 ttcctttcgt actttaattc tggcttgatt gtatcataaa agggagttat agatacatag
     4201 ttaatgcaac aagttatgat acaaaatatg acctctttta tttaataaaa gaggtcattt
     4261 cattttgtct cataatcgat tgtttttgat acggttttta gtaataaatg gagactcttc
     4321 tggtatcatg aatcagaaga gtctccatct gcatacatat gtattttatt tatagcatct
     4381 aaactgtttt cagcaataaa agtaggtttt gtttcactcc acagatgtct atatttggtt
     4441 aaactatcaa ttccctctcc cgttaaaagt aaaacactgt ttataccagc atttttggcc
     4501 aacatcatat cgtttttacc ggaatcgcct actacgaaac acttacttgg atttaaatcg
     4561 tattttttta atgcttcatt gacaaatgta ggttgaggct tcttgcaatc acaattgtct
     4621 tttctagcat gagggcaagt gtatacatcc gttatttgaa tgtcattttt ctctaactca
     4681 tttattaagc tctctaaggc atcagtatat tctgccatag taatacgtcc atgtgaaata
     4741 tgactttgat tcgtaatgat gatatttaga taatgacttt gtgccgcttt ttttaaggcc
     4801 ggtattgtgt ctttaaaaaa attgaaattt tgattaatca gtgttctact atcccctccc
     4861 agcgtaccta acagatccca aaatatagct ttattcatgg atatttgtct ccctctcatt
     4921 ttaagaatag ttaactaaca agccaaggtg cttacagtat ttaaaagtag ttcttcgtaa
     4981 ttaaaacaaa aatattactt tttgaaaaag catattttat tttgccagtt taactatatc
     5041 atatttacag gagccactct ctattcactt tctatatgaa cttcttttga gggaatggat
     5101 atttcgaatc acataatcac tgatatagaa gagacttaga atttcagtta tattttgata
     5161 cagcaaagag tgtaaaaaag aagataccct cgttggcgaa aaacatttga atacaaacct
     5221 tacttttttg atgggatttc catgctagga gcacataaaa aactaaggtg ataataaatt
     5281 tatagtgatt tagtgtggag gttcttttgt taattgaaac cataaatagt aaaaaaatct
     5341 atttttaatg attgtacata ttaaagagaa aattgatata caccagctta tcaaagttga
     5401 gattaatact actactttga cctatgaaga tgattttata aataccttat agtaaagaaa
     5461 agttcaattt tttctgctat catctttttt tataaaagca acgattagtt tcccagatgt
     5521 aaatagaaaa gtgcttttga aacagctcga aaaacataat aatagattgt gagaggagga
     5581 aaaactattg caaaatcatt acgtaagaga tgttactctt gcttagattt tttatttttc
     5641 aagttgtggt attaaaagta gaaaaaatag aaagaaggat aaaaaatgaa aaataaattt
     5701 aagtatttat ttactatttt agccttattg ccaattacta catcgacctt aattactcct
     5761 acaatagcca aagcttctga aaaacaggaa gattctgtta gttatgaaat tgtaaaaaat
     5821 gatctttaca ttcagtttga agaagagtta gctgaattga ttgcttccaa tcaatcaact
     5881 gtttcagtcc ctgatttatt ttctacacaa tcagtattat ctacttctag tcaagataat
     5941 tctattagtg aagagcaatt tttttcttta gtcgaaaaat atgatggagc tgaattgaca
     6001 gctgttgtta attcacaaga tgctttcaca actaaatttg tgaatggtgg ggttaactca
     6061 tatgctactt cttacagagg attaaatgca ttgcgtagcg agttgaagta taatgctggt
     6121 gctttgaaag taggaggtac cttagttggc acagctgggg gattgttagg agtattatta
     6181 ggcatggtta caggggatta tttatctggc cattgcgatg atgcagcagc aggtgttagt
     6241 gcctttattc aagctggttg aatacggcat cgaaaatgta ccactagagc attgtttttt
     6301 accactaagt gcaaagaaat gtaccagtaa gtgcgacgcg gttaccattt caaataataa
     6361 aagcgacaat aatgaccaca aggtcaacta agagccactc atgaaaatca tggagtggct
     6421 cttaatttat tttaatgact catttaatta cggatgccgt aacgttcacg catagaaact
     6481 ttaccgtcta ccagaatttg ataagaatca tgtatgatcc tatctagaat ggcatcagcg
     6541 atttgggggt tgccgagctt ttcgtgccat ccttctggat ggaattgaga acagaaaata
     6601 gttgatgctg ttttaagacg ggattcgatt atttccaata gaaaggtgga attttctaac
     6661 gaaagattgg ttaatagcca ttcatcgatg atgagtaatt gaactttttt atatctgttg
     6721 attatttttc gaaaactacc atctgcttga tttttcgaga tggttaattc atctagtagt
     6781 tcagggagtc ggatgtattt cacgttgtag tattgccggc atgcctgtat tccgaaggca
     6841 ttggcgatat acgttttccc attccctgaa gcgcccatca aaatgatgtt atggtgttct
     6901 tccaaataag tcccactggc tagttttaaa atgaggttct tatctaaatt acggtccgga
     6961 tggtattcga tatcctcaat gctggcagag gcatttctaa agtttgcaga tttaatcaac
     7021 cgctgtagtt tattattttt tcgccgggaa tgctccagat caaccatgag gttgaagcgg
     7081 tcttcgaaac tcatggattg gtactcttta tttgtcatct gttcacgata ggattcaagc
     7141 atgcctgaaa gtttcaattc agctaatttt acttctgttt gctcatttaa catcattatt
     7201 tccctccaaa ataggacgca ccgcgagtga atccatgctt ttcaatgtta gtgtcttcaa
     7261 tatgtgattg gcttgttgct cgcttctgct tgttgccctt tagaatggtc tggataattt
     7321 taacagaagg caaagaagcc agatttaaag ctgttgaaca ggccgtttct atttcatttt
     7381 tagaatactt tttaccaaag ctcttcaaag acatgatcga ctttaaggct tgtttttcat
     7441 tttgataacg gtctaagagg tgttgaacaa cctttactgt tgaggaaccg atggtttcag
     7501 cccattccat cgaggattct ggggtatggt ccacatacat tttgtgatta tctggcatat
     7561 gatctctgac agtcgaatac tgcccaaatt tcccgtacag acgtttatgt gttgcgattc
     7621 gcatggaatt aaaatatagt tcaattagat tctctgtcat tcgaatatct atattttgtt
     7681 gaatgtattc gtatggaacg gaataaaaca tgctttcaac tgagacgtgg tagtttagtt
     7741 gaacctttgc ttttttccag acagacatct tataaggtgc cagtggaaga ggattaagtg
     7801 cgaatttttc ttcttcctcg aaggctctga tcctggatcc tggtttctta gtgaacggtc
     7861 gctcattgaa ttcatttaat ttcattctga tttcacgatt taaatcttcg attgtaaaac
     7921 aatgcgtatt gcgtaaggca gctataatcc aagtggagat gacgcctacg ctgccttcaa
     7981 cactgggctt atccttggga gtagaaactc gggcaggtaa aatgatggac ccgtaatgtt
     8041 cccctagctc tcgatatgat tcattaagga tgacatcgat gccttcattc ttttttacac
     8101 ctgtttttag attatcggga acaattatgt cggtagaacc gccaaaatat tcaaatgcat
     8161 ggttatgtgc cgtaatccaa gccaccgatt tcatcgttag gaatgcttcc gcataagaca
     8221 attggctgca cggtaaggtt gccacaaaga cataagcctt tactttttca cccgtatctc
     8281 gatcgatgac ataagctggc gatccagccc aatccacttc cataatttca ccaggcttcc
     8341 gacggatgcg catagtggct ttatgctttc gcgcgaacgc attgtaatag tcacaaaatg
     8401 tacgataggc gtaagggatt ttcccactca tgcgacactc aactgcgtat tcctgatgaa
     8461 gaagcgtcaa ggtcacgttt ggtttggcca attccttgtg aatcttgtcg aagtcaggca
     8521 ggtgccgtcc attggcttct aattgttttt ctggaaacaa aaattcgcct agccattgat
     8581 cggtcatttc ttccgacaac gccctcgcta tccctttctc ctcagctttt cggataacct
     8641 cagtaatttt ctgacgtgag ttccccgtgc ttgctgcaat actgcgaata ctaattcctt
     8701 cactgtgcat ttcaagtatc cttcgataac gaaacataat aaaaatacct cctgtaaaat
     8761 aaatgtcaca ccctaaggtg tgcacctaca ttatacaaga ggtatttgtg gtacactgct
     8821 ttgcacttac tggtacattt ctttgccgag cctggtaaaa attattgcag agatggtaca
     8881 ttttcgatgc cgtaatcact ggttacacta gaggaggatc tagggtaacc cttactgaag
     8941 gtttccctat tagccatatt gatagtattt atgaagctgt aattaattaa gcaagaaatg
     9001 tggagatgat aaaaagcagt tctctcttgg gtaaagagaa aactgctttt atctttttcg
     9061 ctaatgcttt ttggaattac ctcgctgtct aaaaagggaa gtcacagaaa aaagaattaa
     9121 cacactacct attattattg gtagtacagt taaaagagta atcttactaa gatcaaaatc
     9181 agaacttgct acactattaa taacaaaaaa caagccaacc aaaaaagtaa atactggatt
     9241 tgagtcaata cctcggacac gatttgtgag aatt
//
LOCUS       DAFELK010000189         7959 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.091, whole genome shotgun sequence.
ACCESSION   DAFELK010000189
VERSION     DAFELK010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.091"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            128..1564
                     /locus_tag="LP433_003114"
     CDS             128..1564
                     /locus_tag="LP433_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2007173.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPESVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="LP433_003115"
     CDS             1753..4200
                     /locus_tag="LP433_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL2007174.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="LP433_003116"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="LP433_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL2007175.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="LP433_003117"
     CDS             complement(5690..6793)
                     /locus_tag="LP433_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2007176.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="LP433_003118"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="LP433_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL2007177.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2664 a         1359 c         1730 g         2206 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aagtgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DAFELK010000190         6681 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.098, whole genome shotgun sequence.
ACCESSION   DAFELK010000190
VERSION     DAFELK010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6681
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.098"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            134..1219
                     /locus_tag="LP433_003119"
     CDS             134..1219
                     /locus_tag="LP433_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2007178.1"
                     /translation="MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPN
                     TIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREE
                     TTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRV
                     KKKQIRTLRSKEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIH
                     LTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFG
                     KPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTT
                     LNTYVHLSDQDMKNEFNKYLERKEHKK"
     gene            1216..3108
                     /locus_tag="LP433_003120"
     CDS             1216..3108
                     /locus_tag="LP433_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2007179.1"
                     /translation="MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPS
                     AIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKM
                     LDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
                     YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYF
                     KQLVKRYCKLRLNVDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSE
                     LNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEF
                     VLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKM
                     KKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQ
                     NIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETL
                     KNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGC
                     PHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQI
                     IGSLTG"
     gene            3115..3492
                     /locus_tag="LP433_003121"
     CDS             3115..3492
                     /locus_tag="LP433_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2007180.1"
                     /translation="MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNS
                     IAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVME
                     LEKENKKLQNQIQKLYGDLYNKE"
     gene            3643..4425
                     /locus_tag="LP433_003122"
     CDS             3643..4425
                     /locus_tag="LP433_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HBL2007181.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(4551..5282)
                     /gene="erm(A)"
                     /locus_tag="LP433_003123"
     CDS             complement(4551..5282)
                     /gene="erm(A)"
                     /locus_tag="LP433_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HBL2007182.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVIAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            complement(5340..5399)
                     /locus_tag="LP433_003124"
     CDS             complement(5340..5399)
                     /locus_tag="LP433_003124"
                     /inference="COORDINATES: protein motif:HMM:NF033690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythromycin resistance leader peptide"
                     /protein_id="HBL2007183.1"
                     /translation="MGTFSIFVINKVRYQPNQN"
     gene            5791..6453
                     /locus_tag="LP433_003125"
     CDS             5791..6453
                     /locus_tag="LP433_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2007184.1"
                     /translation="MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGC
                     GSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIV
                     SRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCF
                     KFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVW
                     TK"
BASE COUNT         2405 a          902 c         1272 g         2102 t
ORIGIN      
        1 ttaaccatag tataataaat aatagtagtt aaagtagttt aagaggagat attaaaggga
       61 tattttactt taaataaaaa ttaacaaggt ttataatttg tagtagttaa agtatttaaa
      121 gaggtgggaa catgtgaagg ttcaaaggat agaagtggag aataagccgt atccattgta
      181 tttattacta gataaagaat accagctaat agaaccagta atgaaattta ttaaatactt
      241 agataatact ggtaagtctc ctaataccat taaggcatac tgctatcatt taaagttgct
      301 gtacgagttc atggaacaga gaggtgttat tcttaatgat attaactttg agttgttagc
      361 agacttcgta ggttggttga gatatccttc agcatcaaat gtaattgatc ttcagtcaaa
      421 aaaagccata agagaagaaa cgacagtgaa tacaatttta aatgtagtta tgagttttct
      481 tgattattta agtagattag gagaatttaa atcaattgat gtatttaaac aagcaaaggg
      541 aagaaatttc aaaggatttt tacatcatgt taataagggt agataccaaa agaatgtctt
      601 aaagttaagg gttaaaaaga aacagataag aacattgaga tcaaaggaag ttaagcaaat
      661 tattgatgct tgtcatacga aaagagataa attaatttta atgcttatgt atgagggtgg
      721 tttaagaatc ggtgaagtgt tatcgcttag gcttgaagat attgtcactt gggacaatca
      781 aatccattta acacctagag atgttaatgt taatgaagct tatattaaat taaggaagga
      841 aagaacaata catgtgagta aagaacttat gtcactttat acagattact tgatatatga
      901 gtatagtgag gaattggagc atgattatgt ttttatttcc ttaaaagaag gctattttgg
      961 gaaaccacta aagtaccaaa gtgttcttga tctagttaga agaatagtta aaaggactgg
     1021 aatagaattt acatcacata tgcttcgcca cactcacgca acgcagctaa ttagggaagg
     1081 atgggatgtt gcgttcgttc aaaagagatt aggtcacgca catgttcaga caacgttaaa
     1141 tacctatgtt catctttcag atcaggatat gaaaaatgag tttaataaat acctcgagag
     1201 aaaggagcat aagaaatgaa tgcttctagt aaaaggaaaa ttattagtca gagtgagatt
     1261 agcaaaaaaa tagctgtaat gaatgaagaa atgcaggggt tttgggctaa taatagttgg
     1321 gatataagaa aatgtccaca tccttctgcc atagaattaa gtaagaatcc tgctttaagg
     1381 aatcgttggg ttcgttttga acgtgttaaa aatctgtggt taagaacaga attgaaatat
     1441 ttttattttt accatttaaa caatggaata tggaatgcaa aaactgtctg gattagaaaa
     1501 ggaacagtaa ttaataaaat gttagatttc ttagatttaa agtatcctag cattacttca
     1561 attactgaag ttcctattga aaaagcaatg acggagtata gaacttattt gacaaaacgg
     1621 ggtgttagaa ttaccactac taattataag attactgcta atcaagaaaa aacacctgta
     1681 aaagctaatt cctactatgt tactaatcta aaacaattta tggagtttta tgagaacttt
     1741 tattttgatg gagaggagtg ggataaagac gtttgggata gacgtaactt acctttgcca
     1801 gatgataagg ttaacccaac acaatatgaa tatacaatta actttaaagg gtttcggaat
     1861 acatatttta aacaacttgt aaaaagatat tgtaagttga gattgaacgt ggatagcttt
     1921 tcctatgtaa gtgatattgc ccaaagactt aaagagttct ttaattttct ggacatgaaa
     1981 tttaaacaag ttcagagagt acaccaatta acgagagtgg aaattgaagc atatttaagt
     2041 gaactaaaca tgatgggaat aaaacctagt acaataactg ggaggatctc tatattggaa
     2101 ggactattta gtacccttct taggctagaa tgggatgatg ttccttccaa aatattaatt
     2161 tattctgagg actatccgaa aataccaaga gcaaaaccac gctttataga tgaattcgtc
     2221 ctagagcaat tgaacagtca tcttgataaa ttacccgaat atatagctac gatgactatg
     2281 attgttcaag aatgtggaat gaggataagt gaattgtgca ccttgaaaaa aggctgtcta
     2341 ttagaggaca aagatggaga tttcttttta aagtattatc aatggaaaat gaaaaaggag
     2401 catatagttc caatatctaa agaggtagct ttacttatta aagttcggga agataaagtt
     2461 tcagaggaat ttccagatag tgaatacctc tttccaagaa aagatggatc gccattaaaa
     2521 caagaaacat ttagaggtga gttaaataaa ttagcttatg agcaaaatat agtggataaa
     2581 tcaggtgaga tttatagatt ccatgcccat gcctttcgcc atacagtagg aacaagaatg
     2641 attaacaacg ggatgcccca gcatattgtg cagaaatttt tggggcatga aagcccagaa
     2701 atgacaagca gatacgctca tatctttgat gaaactctaa aaaatgaatt tactaaattt
     2761 caggaaaaac tggttaccaa taatggagat gtgcttgatc tagatgaaga taatgaagtc
     2821 gatgatgtag agcttcaatg gttcaagaaa aatataaatg cacaagtgct tccaaatggt
     2881 tattgtagat tgccagtagt agcaggtggt tgtccacatg cgaatgcatg cttagattgc
     2941 actcacttct gtaccagtaa gcaattctta ccacagcacg aagaacagtt agagcgtaca
     3001 gaagagttat tagccatagc taaggataaa caatggcaaa gacaagtaga gactaatagc
     3061 cgtgttaaag agcgtttaga acaaatcatt ggaagtttga cggggtaatt atcaatggat
     3121 aaacaagtta gaaatacaac agaaattgta cgtttggcga agcagaaatc aaaaaagaca
     3181 agggaaaaag tagacaaagc gatttctaaa ttttcgattg aaggtaaagt tattaatttt
     3241 aattcaatag caaaggaagc taatgtttct aaatcatggc tttataagga acacgatatt
     3301 aggcaaagaa tcgaatccct tcgtgagcgt caaataacag caaatgtagt ctcaaaaccc
     3361 aagaaaagtt ctcgttcgga ggaaatcctt attaaaacct taaaaagaag agtaatggaa
     3421 ttagaaaaag aaaataaaaa attacagaac caaattcaaa aattatatgg agatctgtat
     3481 aataaagaat aattattaat ctgtagacaa attgtgaaag gatgtactta aacgctaacg
     3541 gtcagcttta ttgaacagta atttaagtat atgtccaatc tagggtaagt aaattgagta
     3601 tcaatataaa ctttatatga acataatcaa cgaggtgaaa tcatgagcaa tttgattaac
     3661 ggaaaaatac caaatcaagc gattcaaaca ttaaaaatcg taaaagattt atttggaagt
     3721 tcaatagttg gagtatatct atttggttca gcagtaaatg gtggtttacg cattaacagc
     3781 gatgtagatg ttctagtcgt cgtgaatcat agtttacctc aattaactcg aaaaaaacta
     3841 acagaaagac taatgactat atcaggaaag attggaaata cggattctgt tagaccactt
     3901 gaagttacgg ttataaatag gagtgaagtt gtcccttggc aatatcctcc aaaaagagaa
     3961 tttatatacg gtgagtggct caggggtgaa tttgagaatg gacaaattca ggaaccaagc
     4021 tatgatcctg atttggctat tgttttagca caagcaagaa agaatagtat ttctctattt
     4081 ggtcctgatt cttcaagtat acttgtctcc gtacctttga cagatattcg aagagcaatt
     4141 aaggattctt tgccagaact aattgagggg ataaaaggtg atgagcgtaa tgtaatttta
     4201 accctagctc gaatgtggca aacagtgact actggtgaaa ttacctcgaa agatgtcgct
     4261 gcagaatggg ctatacctct tttacctaaa gagcatgtaa ctttactgga tatagctaga
     4321 aaaggctatc ggggagagtg tgatgataag tgggaaggac tatattcaaa ggtgaaagca
     4381 ctcgttaagt atatgaaaaa ttctatagaa acttctctca attaggctaa ttttattgca
     4441 ataacaggtg cttactttta aaactactga tttattgata aatattgaac aatttttggg
     4501 aagaataaag cgtcctcttg tgaaattaga gaacgcttta ttactttaat ttagtgaaac
     4561 aatttgtaac tattgaaaat agaaagaaat tgttccttcg atagtttatt aatattagtg
     4621 acatttgcat gcttcaaagc ctgtcggaat tggtttttag tgaaaagaac acgatattca
     4681 cggtttaccc acttataaac aaaagatcga tactttttgt agtccttctt tgaaatcaat
     4741 ggttgatgtc gttcaagaac aatcaataca gagtctacac ttggcttagg atgaaaatat
     4801 agtggtggta cttttttgag catttttata tccatctcca ccattaatag taaacccaaa
     4861 gctcgttgca gattttgcaa tcttttcgca aatcccttct caacgataag atagctatat
     4921 ttagcctgac tttcaaaggt aattcttttg acaatatccg tactgatgtt ataaggaata
     4981 ttaccatata tcttatagtt tatatgtttt gggaaggaaa attttagaat atccgtttga
     5041 atcactttta tattctcaga ggggtttacc gcttctttag tcacttgaca taagcctcca
     5101 tcaatttcta tagcaataac tgatcgactc attttgacta gctctttggt aaaatgtcct
     5161 tttcctgatc cgatttctat tacgttgtct tgtttactga tattcgtgtg attcaatatt
     5221 tcttttacat gctttttaga agtaataaaa ttttgcgtgt ctttagggtt tttctggttc
     5281 attataacct tctccttact ggttataatg aactgacatt aagcgttcat tataaccaat
     5341 taattttgat ttggttgata acgaacttta ttaataacaa atatagaaaa agtacccata
     5401 cttttatctc ctttccattt ttttcattat gaatgagata aagtaatttc tactactgcg
     5461 atactggtgc acataattga aacctcctta tgtaactgaa tatgattgta tcatcttttc
     5521 attttagaat aaacctttat atgtaatttt gcacttgaca cttcagatgg acgttttctt
     5581 caaaataata tgttttgaaa cttgataaga gaagccactg tctttactaa aaagtaaagg
     5641 ctgcgataaa ggacagtgac tttaataaag ttgcactgtt gtattgtctt tggataaaat
     5701 tgtctaaagg gaagttttat ccccaacgaa aaaacatcta aagtggtaag taatgaaaga
     5761 atgtcgataa agtaggaatg ggggatcttt ttgaatacaa tagaatcaca gtttgataag
     5821 gttgcagaag attacgattt cgtgaatgag cttttgaatg attattcatt ctttgtgtct
     5881 aatatgtctc caaagaaagg cagagcatta gatatcggat gtggctcggg tttgttagtg
     5941 gagaaattag caagttatta tgatgaagtg gtagggattg atatttctaa tcaaatgctc
     6001 gatcttgcca aatctaaacg tcaactaaca aatacggtct atctgaatat gaatgcagaa
     6061 caacttaatt ttaatgagaa gtttgatttt attgtaagcc gaacaacctt tcatcatttg
     6121 gatgatatag ccagcgtaat acagcaaatg aaggaactgt tgaatgagga aggaagaata
     6181 gttattcttg ataatgtatc tgaagtcgag acaccgccta cctatgttta taaattaggg
     6241 gcaatccaag agtttttacc gcattgtttc aaatttggaa taaaaaatgc gattagaatt
     6301 tataatcaca acacatctaa atcatggctt gagcatttag cttcagataa gtacctatct
     6361 gaacaaaatt attacgattt atatgaaaag ttgttgcctg gatgccaatt ccataaaatg
     6421 ggttgggcaa tgggggttgt ctggacaaaa taacttaaag ctgtggcttt gaaaagttga
     6481 atttgtgatt gttttcagag ctatcgggtg ctttagtata aataacaatg aataaaaaat
     6541 cagcctgtat cttatgttac tattaagtaa tttaagatac aggttttact atttttgaaa
     6601 taagtacctt ccacttcaaa tacatgtatt caaagtgaaa gtattgattt aaatgattct
     6661 tttgtaattt actcttgata a
//
LOCUS       DAFELK010000191         5981 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.104, whole genome shotgun sequence.
ACCESSION   DAFELK010000191
VERSION     DAFELK010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.104"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            31..207
                     /locus_tag="LP433_003126"
                     /pseudo
     CDS             31..207
                     /locus_tag="LP433_003126"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(292..3216)
                     /locus_tag="LP433_003127"
     CDS             complement(292..3216)
                     /locus_tag="LP433_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBL2007185.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            3362..3937
                     /locus_tag="LP433_003128"
     CDS             3362..3937
                     /locus_tag="LP433_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2007186.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            4151..4846
                     /gene="vanR"
                     /locus_tag="LP433_003129"
     CDS             4151..4846
                     /gene="vanR"
                     /locus_tag="LP433_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL2007187.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4824..5975
                     /locus_tag="LP433_003130"
     CDS             4824..5975
                     /locus_tag="LP433_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2007188.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPGFCCKVLNKE"
BASE COUNT         1851 a         1132 c         1131 g         1867 t
ORIGIN      
        1 attttattct ttatttaaaa ctttgcaaca gaaccctttt ggggtaccct caaggtggag
       61 atgtttaacc tggatacgtt tgacagacca gcgtacttag accggaaaat caaggcatac
      121 atcgcgttct tcaacaatga acgcgttact ttggatatgg gattagcaat tcctacggaa
      181 gagaagattc tacaaatgat tgcataaacg ctacaaaaaa agaccacaca tttttacatg
      241 catggtctaa aatactttgt ttttttacct gtctacttga cagggggcag ttcactctga
      301 gttaaaatgg tattctccta gtaaattaat atgttcccaa cctaagggcg acatatggtg
      361 taacaaatct tcattaaagc tacctgtccg ttttttatat tcaactgctg ttgttaggtg
      421 gagagtattc caaatactta tagcattgat aattatgttt aaagcactgg ctctttgcaa
      481 ttgatgctgt atggtgcgtt ctctaagctc accttgtttt ccgaagaaaa tagctcttgc
      541 caatccattc atggcttctc ctttattcaa tcctctttgt atttttcttc ttaatgattc
      601 atccgatata taattcaaaa taaagatcgt tttttctatt cggcccatct cacgtaaggc
      661 tgtagctaag ctgttttgtc ttgaatagga acctagcttc cccataataa gggatgctga
      721 aactgttccc tcccttatag aatgagctaa tcgcaaaaca tcctcataat tttctttaat
      781 gacctttgta tttatttgtc cacgtaaaat ggcttctagt tttggatact cacttgcttt
      841 atctatcgta aataattttg agtccgataa atcccttatt cttggggcaa atttaaatcc
      901 taataaatga gtcagtccga atatttggtc agtgtaaccg gcagtgtctg tataatgttc
      961 ctctatgttt agatccgtct catgatgtaa caaaccatcc aaaacatgaa tcgcatctct
     1021 tgaattagta tgaataatct ttgtgtagta agaagagaat tgatcacttg taaatcggta
     1081 gatggtggct ccttttccag ttccataatg tggatttgca tctgcatgta gtgatgaaac
     1141 acctagctgc attctcatac catctgacga agatgttgta ccgtcgcccc aatagaaagg
     1201 caattgtaat ttatgatgaa agtttactaa tatggcttgg gctttattca tggcatcttc
     1261 atacatgcgc cattgagata cattggctag ttgcttatat gtaagtccgg gtgtggcttc
     1321 ggccatcttg ctcaagccaa tattcattcc cattcctaaa agggcagcca tgataatgat
     1381 tgtttcttcc ttatctggtt ttcgattatt ggaagcatga gtgaattgct catgaaatcc
     1441 tgttatatgg gccacatcca tgagtaaatc agttaatttt attcttggta gcatctgata
     1501 aaggcttgca ctaaattttt ttgcttcttc tggaacatct ttttctaagc gtgcaagtga
     1561 tagctttcct ttttcaagag aaaccccatc taacttattg gaattggcag ctaaccactt
     1621 taacctttca ttaaagctgc tggttctctc cgttatataa tcttcgaatg ataaactaac
     1681 tgataatctc gtattcccct tcgattgatt ccatgtatct tccgaaaaca aatattcctc
     1741 aaaatcccta tattgtctgc tgccaacaat ggaaacatct cctgcccgaa catgctcccg
     1801 aagttctgtt aaaacagcca tttcatagta atgacgatta attgttgtac catcatcctc
     1861 gtataaatgt cttttccatc gttttgaaat aaaatccaca ggtgagtcat caggcacttt
     1921 tcgctttcca gattcgttca ttcctcggat aatctcaaca gcttgtaaaa gtggctcatt
     1981 tgcctttgta gaatgaaatt ccaatactct taatagcgtt ggcgtatatt ttcttagtga
     2041 ataaaaccgt ttttgcagta agtctaaata atcatagtcg gcaggacgtg caagttcctg
     2101 agcctcttct actgaagaga caaaggtatt ccattcaata accgattcta aaaccttaaa
     2161 aacgtctaat ttttcctctc ttgctttaat taatgcttgt ccgatgttcg taaagtgtat
     2221 aactttctca tttagctttt taccgttttg tttctggatt tcctcttgag ccttacgacc
     2281 ttttgataac aaactaagta tttgcctatc atgaatttca aacgctttat ccgttagctc
     2341 ctgagtaagt tgtaataaat agatggttaa tatcgaataa cgtttatttt cttgaaagtc
     2401 acggaatgca tacggctcgt atcttgagcc taagcgagac agctgcaaca ggcggttacg
     2461 gtgcaaatga ctaatttgca ctgtttctaa atccattcct cgtatgtatt cgagtcgttc
     2521 tattattttt agaaaagttt cgggtgaagg atgacccggt ggctctttta accaacccaa
     2581 tatcgtttta ttggattcgg atggatgctg cgaggtaata atcccttcaa gcttttcttt
     2641 ttgctcattt gttagagatt tactaaccgt attaaatagc ttcttttcag ccattgccct
     2701 tgcttcccac accattcttt caagtgtagt gatagcaggc agtataattt tgttttttct
     2761 tagaaaatct atgcattcat gcagtagatg aatggcatca ccattttcca aagctaattg
     2821 atgaaggtac ttaaatgtca ttcgatattc actcagggta aaagttacaa agtcgtattc
     2881 acttcgaatt tctttcaaat gatcccaaag tgtattttcc ctttgaggat aatgatcaag
     2941 cgaggatgga ctaacaccaa tctgtttcga tatatattgt atgaccgaat ctgggatgct
     3001 tttgatatga gtgtatggcc aaccgggata ccgaagaaca gctaattgaa cagcaaatcc
     3061 taaacggttt tcttccctcc ttcgcttatt aactatttct aaatcccgtt tggaaaaagt
     3121 gaagtaggtc cccagtatcc attcatcttc agggatttgc ataaaagcct gtctctgttc
     3181 cggtgtaagc aattctctac ctctcgcaat tttcattcag tatcattcca tttctgtatt
     3241 ttcaatttat tagttcaatt atatatcaat agagtgtact ctattgatac aaatgtagta
     3301 gactgataaa atcatagtta agagcgtctc ataagacttg tctcaaaaat gaggtgatat
     3361 tttgcggaaa atcggttata ttcgtgtcag ttcgactaac cagaatcctt caagacaatt
     3421 tcagcagttg aacgagatcg gaatggatat tatatatgaa gagaaagttt caggagcaac
     3481 aaaggatcgc gagcaacttc aaaaagtgtt agacgattta caggaagatg acatcattta
     3541 tgttacagac ttaactcgaa tcactcgtag tacacaagat ctatttgaat taatcgataa
     3601 catacgagat aaaaaggcaa gtttaaaatc actaaaagat acatggcttg atttatcaga
     3661 agataatcca tacagccaat tcttaattac tgtaatggct ggtgttaacc aattagagcg
     3721 agatcttatt cggatgagac aacgtgaagg gattgaattg gctaagaaag aaggaaagtt
     3781 taaaggtcga ttaaagaagt atcataaaaa tcacgcagga atgaattatg cggtaaagct
     3841 atataaagaa ggaaatatga ctgtaaatca aatttgtgaa attactaatg tatctagggc
     3901 ttcattatac aggaaattat cagaagtgaa taattagcca ttctgtattc cgctaatggg
     3961 caatattttt aaagaagaaa aggaaactat aaaatattaa cagcctccta gcgatgccga
     4021 aaagcccttt gataaaaaaa gaatcatcat cttaagaaat tcttagtcat ttattatgta
     4081 aatgcttata aattcggccc tataatctga taaattatta agggcaaact tatgtgaaag
     4141 ggtgataact atgagcgata aaatacttat tgtggatgat gaacatgaaa ttgccgattt
     4201 ggttgaatta tacttaaaaa acgagaatta tacggttttc aaatactata ccgccaaaga
     4261 agcattggaa tgtatagaca agtctgagat tgaccttgcc atattggaca tcatgcttcc
     4321 cggcacaagc ggccttacta tctgtcaaaa aataagggac aagcacacct atccgattat
     4381 catgctgacc gggaaagata cagaggtaga taaaattaca gggttaacaa tcggcgcgga
     4441 tgattatata acgaagccct ttcgcccact ggagttaatt gctcgggtaa aggcccagtt
     4501 gcgccgatac aaaaaattca gtggagtaaa ggagcagaac gaaaatgtta tcgtccactc
     4561 cggccttgtc attaatgtta acacccatga gtgttatctg aacgagaagc agttatccct
     4621 tactcccacc gagttttcaa tactgcgaat cctctgtgaa aacaagggga atgtggttag
     4681 ctccgagctg ctatttcatg agatatgggg cgacgaatat ttcagcaaga gcaacaacac
     4741 catcaccgtg catatccggc atttgcgcga aaaaatgaac gacaccattg ataatccgaa
     4801 atatataaaa acggtatggg gggttggtta taaaattgaa aaataaaaaa aacgactatt
     4861 ccaaactaga acgaaaactt tacatgtata tcgttgcaat tgttgtggta gcaattgtat
     4921 tcgtgttgta tattcgttca atgatccgag ggaaacttgg ggattggatc ttaagtattt
     4981 tggaaaacaa atatgactta aatcacctgg acgcgatgaa attatatcaa tattccatac
     5041 ggaacaatat agatatcttt atttatgtgg cgattgtcat tagtattctt attctatgtc
     5101 gcgtcatgct ttcaaaattc gcaaaatact ttgacgagat aaataccggc attgatgtac
     5161 ttattcagaa cgaagataaa caaattgagc tttctgcgga aatggatgtt atggaacaaa
     5221 agctcaacac attaaaacgg actctggaaa agcgagagca ggatgcaaag ctggccgaac
     5281 aaagaaaaaa tgacgttgtt atgtacttgg cgcacgatat taaaacgccc cttacatcca
     5341 ttatcggtta tttgagcctg cttgacgagg ctccagacat gccggtagat caaaaggcaa
     5401 agtatgtgca tatcacgttg gacaaagcgt atcgactcga acagctaatc gacgagtttt
     5461 ttgagattac acggtataac ctacaaacga taacgctaac aaaaacgcac atagacctat
     5521 actatatgct ggtgcagatg accgatgaat tttatcctca gctttccgca catggaaaac
     5581 aggcggttat tcacgccccc gaggatctga ccgtgtccgg cgaccctgat aaactcgcga
     5641 gagtctttaa caacattttg aaaaacgccg ctgcatacag tgaggataac agcatcattg
     5701 acattaccgc gggcctctcc ggggatgtgg tgtcaatcga attcaagaac actggaagca
     5761 tcccaaaaga taagctagct gccatatttg aaaagttcta taggctggac aatgctcgtt
     5821 cttccgatac gggtggcgcg ggacttggat tggcgattgc aaaagaaatt attgttcagc
     5881 atggagggca gatttacgcg gaaagcaatg ataactatac gacgtttagg gtagagcttc
     5941 cagggttctg ttgcaaagtt ttaaataaag aataaaatcc c
//
LOCUS       DAFELK010000192         5630 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.107, whole genome shotgun sequence.
ACCESSION   DAFELK010000192
VERSION     DAFELK010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.107"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            108..191
                     /locus_tag="LP433_003131"
     CDS             108..191
                     /locus_tag="LP433_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBL2007189.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            316..1053
                     /gene="erm(B)"
                     /locus_tag="LP433_003132"
     CDS             316..1053
                     /gene="erm(B)"
                     /locus_tag="LP433_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL2007190.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1199..1483
                     /locus_tag="LP433_003133"
     CDS             1199..1483
                     /locus_tag="LP433_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBL2007191.1"
                     /translation="MPTKRSGPLVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFR
                     KKKLTKTNVKELLEGKENLVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            1646..2311
                     /locus_tag="LP433_003134"
                     /pseudo
     CDS             1646..2311
                     /locus_tag="LP433_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2347..2592
                     /locus_tag="LP433_003135"
     CDS             2347..2592
                     /locus_tag="LP433_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2007192.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2695..3564
                     /locus_tag="LP433_003136"
     CDS             2695..3564
                     /locus_tag="LP433_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL2007193.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3545..4279
                     /locus_tag="LP433_003137"
     CDS             3545..4279
                     /locus_tag="LP433_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2007194.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4312..5220
                     /locus_tag="LP433_003138"
     CDS             4312..5220
                     /locus_tag="LP433_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBL2007195.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5217..5615
                     /locus_tag="LP433_003139"
     CDS             5217..5615
                     /locus_tag="LP433_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2007196.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKGSVAKF"
BASE COUNT         2015 a          822 c         1133 g         1660 t
ORIGIN      
        1 tatttgatag tagatttaaa actttgcaac agaaccattt tgtgtataat aggaattgaa
       61 gttaaattag atgctaaaaa tttgtaatta agaaggaggg attcgtcatg ttggtattcc
      121 aaatgcgtaa tgtagataaa acatctactg ttttgaaaca gactaaaaac agtgattacg
      181 cagataaata aatacgttag attaattcct accagtgact aatcttatga ctttttaaac
      241 agataactaa aattacaaac aaatcgttta acttctgtat ttatttacag atgtaataac
      301 ttcaggagtg attacatgaa caaaaatata aaatattctc aaaacttttt aacgagtgaa
      361 aaagtactca accaaataat aaaacaattg aatttaaaag aaaccgatac cgtttacgaa
      421 attggaacag gtaaagggca tttaacgacg aaactggcta aaataagtaa acaggtaacg
      481 tctattgaat tagacagtca tctattcaac ttatcgtcag aaaaattaaa actgaacatt
      541 cgtgtcactt taattcacca agatattcta cagtttcaat tccctaacaa acagaggtat
      601 aaaattgttg ggagtattcc ttaccattta agcacacaaa ttattaaaaa agtggttttt
      661 gaaagccatg cgtctgacat ctatctgatt gttgaagaag gattctacaa gcgtaccttg
      721 gatattcacc gaacactagg gttgctcttg cacactcaag tctcgattca gcaattgctt
      781 aagctgccag cggaatgctt tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt
      841 acccgccata ccacagatgt tccagataaa tattggaagc tatatacgta ctttgtttca
      901 aaatgggtca atcgagaata tcgtcaactg tttactaaaa atcagtttca tcaagcaatg
      961 aaacacgcca aagtaaacaa tttaagtacc gttacttatg agcaagtatt gtctattttt
     1021 aatagttatc tattatttaa cgggaggaaa taattctatg agtcgctttt ttaaatttgg
     1081 aaagttacac gttactaaag ggaatggaga taaattatta gatatactac tgacagcttc
     1141 caagaagcta aagaggtccc tagcgcctac ggggaatttg tatcgataag gggtacaaat
     1201 tcccactaag cgctcgggac cccttgtagg aaaatgtcct aagtgtggca acaatattgt
     1261 attaaaaaaa tcgttttatg gttgttcaaa ttatcctgaa tgtaagttta ctttagctga
     1321 acattttaga aagaaaaaac taaccaaaac gaatgtaaaa gaattactgg agggaaaaga
     1381 aaacctggta aaaggaatca aaaacaaaga gaaaaagccc tacaatgccg ttgtaaaaat
     1441 tggggaaaag ggatatattg attttatctc tttttcaaaa taaacatggg gctgacccaa
     1501 aagtagctcc tatatgaaaa atagaggtct ttccatttag atagtagtgg aaagacctct
     1561 atttatcttt tgaaagtgaa tacaaaaata aagcacactc tgctataata taggtgatta
     1621 atccatttga gagaggtgct ttatcatgta tcaaaattat accataaacc aactttgttt
     1681 gcctatagat cttgaaatta aattagaaga aaatgatttt gctcatgcca ttgtgcagtt
     1741 tgttgactct attcccgatg aagtctttct tccttattat caatctatgg gtagacccca
     1801 atatcatcct cgtatgctac tttccattat tctttgtgcc tatattcaag gggtttattc
     1861 gggccgccaa atacaaaata tgctgataga tagtattcgg atgcgctact tatctcaaga
     1921 gcaattccct aactttcgta ctattaatcg ttttcgcgtt catccgatta tgaacgatat
     1981 tctagatcat tcatttgttc aatttcgtga gctactggtt caaagtggct taatcagtgg
     2041 cagtgctcta tacattgatg gtacaaaaat tgaagcggat gcgaataaat actctttcgt
     2101 ttggaaaaaa agtattttaa agtataagga tagccttgat caaaaagccc ttgaaaacta
     2161 ccaacaaatg gtggaaacaa aaatcttacc tgagttaata gatgatttaa aggatgaact
     2221 ttctatagaa gagattgaaa ggattcgtca atctttggaa gaaaaggaaa atcaattaat
     2281 tgaagcgatt gaccaaaccg aaacagtaga agggggctga cccattatta ataaggagtg
     2341 gacaacatga ttgatgtaaa tgagctattg gaagaagcta ttagagaaac tgaaaatcta
     2401 aatgatggcg aagtttttct tgttaaagat ttattcaagg gatatgtggg gaataggata
     2461 cccagaaagg atcgacttct gcttggaacg ttatttttaa accatgttag caaaatgaat
     2521 ggtaatttaa aggctattga aaagacttca tctaatcagc agaggtataa aaagacaatt
     2581 gataagtttt aactatcttt tgtgaaatta aaaaaattat aaatatgttg agtagaagca
     2641 aaagatttgg cttggaattt ttacagcagt gaatcgataa aaggagcatg cttgatggta
     2701 gataatatta ttaaatcagt agcagagaaa ttatcctctc tgtcttatat agaaggtatt
     2761 gttttaggtg gttcacgtgc aaggggcacc catacagagg attcggatat agatatcggc
     2821 atctattaca attcagaatc atttgacata aatactatta atcaattcgc tacaaagctg
     2881 gatgatgagc atagaaataa ccttgttgta cctcccggag catggggtga ttggattaat
     2941 ggcggcggat ggttagtcat aaacgggtat catgtggatt taattttacg tgatattaaa
     3001 cgtgtggaac aaataatgaa agatacagag cacggaattg ttactgccaa ttatcagact
     3061 gggcatcccc atggttatat tagtgcaatg tatcgaggag aattagcgat tagcaaaata
     3121 ctatatgcta agaatgaaag cttatgcgaa ttaaaaaaac aggcagaaac ttatcccaat
     3181 gctttgcaga aaagtttagt taactttttt atgtttgaag cagggttctc tttaatgttt
     3241 gtaaaagcaa attcgggaac agacgataaa tattatattg cgggtcatgt ttttcgtata
     3301 gtttcatgtt taaatcaagt gttatttgca tgtaataatg cttattgtat caacgaaaag
     3361 aaagctataa aactgcttga aacttttgaa cataaacctg aaaaatatac cgagaaggta
     3421 aatcatattt ttgaagtact cggtatctca ctttttgaat gctacgacat gaccgagaag
     3481 ctttataatg aagtgaatga aattgtatcg gagataaata actttttaaa cgaggagagt
     3541 tcagatgaaa gaaaacaaat atgatgataa tatatttttt caaaaataca gtcaaatgag
     3601 tcgctcgcag aaaggactgg ctggtgcggg agaatgggag actttgaaaa agatgctacc
     3661 tgattttaag ggtaagcgtg tgcttgattt aggatgcggc tatggatggc actgtatata
     3721 tgcgatggaa aacggtgctt cctctgtagt aggtgttgat atttctcata aaatgctcga
     3781 agtagcaaaa ggaaaaaccc attttccaca gattgaatat gaatgctgtg ccatagaaga
     3841 tgtggatttc ccagaggaga gctttgatgt aatactaagt tcgcttgcgt ttcattatgt
     3901 agcagactat gagaatttaa taaaaaagat atataggatg ctgaaggctg gtggcaattt
     3961 agtttttaca gttgaacatc ctgtttttac tgctcatgga acacaagact ggtattataa
     4021 cgaaaaagga gaaatactgc atttcccggt ggacaattat tattatgagg gcaaacggac
     4081 agctatgttt ttggaagaaa aggttacaaa atatcataga acactgacca catatctaaa
     4141 tacactgctt tcaaatagtt ttataataaa tcagattgtg gagccacagc cgccagagaa
     4201 catgatggat attccgggga tggcggatga aatgcgacgc ccaatgatgc tgattgtatc
     4261 ggcaaaaaag aagatgtaat aatatagaaa aaataaacga ggagtatgta aatgagatca
     4321 gaaaaagaaa tgatggattt agtactttct ttagcagaac aggatgaacg tattcgaatt
     4381 gtgacccttg aggggtcacg cgcaaatatt aatataccta aagatgaatt tcaggattat
     4441 gatattacat attttgtaag tgatatagaa ccgtttatat ctaatgatga ctggcttaat
     4501 caatttggga atataataat gatgcaaaag ccggaggata tggaattatt cccacctgaa
     4561 gaaaagggat tttcctatct tatgctattt gatgattaca ataaaattga tcttacctta
     4621 ttgcccttgg aagagttaga taattaccta aagggcgata aattaataaa ggttctaatt
     4681 gataaagatt gtagaattaa aagggacata gttccgactg atatagatta tcatgtaaga
     4741 aagccaagcg caagggagta tgatgattgc tgcaatgaat tttggaatgt aacaccttat
     4801 gttattaaag gattgtgccg taaggaaatt ttatttgcta ttgatcattt taatcagatt
     4861 gttcgccatg agctgctgag aatgatatca tggaaggtcg gcatcgaaac aggctttaaa
     4921 ttaagtgtag gcaagaacta taagtttatt gaaaggtata tatccgagga tttgtgggag
     4981 aaacttttgt ccacctaccg gatggattcc tatgaaaaca tatgggaagc attatttcta
     5041 tgccatcaat tgttcagggc ggtatccggt gaggtggcgg aaaggcttca ttatgcctat
     5101 ccggagtatg ataggaatat aacaaaatat accagggaca tgtataaaaa atacactggt
     5161 aaaaccggct gcctggatag cacatatgcc gctgatatag aagagaggcg ggaacagtga
     5221 ttacagaaat gaaagcaggg cacctgaaag atatcgataa acccagcgaa ccatttgagg
     5281 tgataggtaa gattataccg aggtatgaaa acgagaattg gacctttaca gaattactct
     5341 atgaagcgcc atatttaaaa agctaccaag acgaagagga tgaagaggat gaggaggcag
     5401 attgccttga atatattgac aatactgata agataatata tctttactac caagacgata
     5461 aatgcgtcgg aaaagttaaa ctgcgaaaaa attggaaccg gtacgcttat atagaagata
     5521 tcgccgtatg taaggatttc agggggcaag gcataggcag cgcgcttatc aatatatcta
     5581 tagaatgggc aaagggttct gttgcaaagt tttaaataaa gaataaaatc
//
LOCUS       DAFELK010000193         3720 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.129, whole genome shotgun sequence.
ACCESSION   DAFELK010000193
VERSION     DAFELK010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.129"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            complement(531..656)
                     /locus_tag="LP433_003140"
     CDS             complement(531..656)
                     /locus_tag="LP433_003140"
                     /inference="COORDINATES: protein motif:HMM:NF019687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007197.1"
                     /translation="MLFPPFKSSKSRKNPSDKYSYHWDFNTKIAVYYTLIATDAL"
     gene            656..2581
                     /gene="tet(S)"
                     /locus_tag="LP433_003141"
     CDS             656..2581
                     /gene="tet(S)"
                     /locus_tag="LP433_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_063856411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HBL2007198.1"
                     /translation="MKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSGTTKTD
                     TMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAILLISAK
                     DGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIKQTVNL
                     NLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSLYPVYH
                     GSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLYSGTLH
                     LRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGDKKRLP
                     HREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIVLSFLG
                     EVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASIGLSVT
                     PLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKYCANIL
                     NTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAFQPRRP
                     NNRIDKVRHMFNKINLH"
     gene            2669..2836
                     /locus_tag="LP433_003142"
     CDS             2669..2836
                     /locus_tag="LP433_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL2007199.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(3350..3706)
                     /locus_tag="LP433_003143"
     CDS             complement(3350..3706)
                     /locus_tag="LP433_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2007200.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLT
                     NIENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVT
                     IGKVIQAIYGEKCKFN"
BASE COUNT         1327 a          577 c          618 g         1198 t
ORIGIN      
        1 tatttgatag tagatttaaa actttgcaac agaacccttt taatgatatt ttccaagtca
       61 aacttaatat taacaattca aaactattgg aaccactgca aaatattttg ttaagcagta
      121 tatatttcaa aaattatacg taatatattt gtagaaaggt tgtggacagt tgtcctattg
      181 acctgaaaag taatataata gctggatgaa taaagaatcc cttatgaact tgtaaatcgt
      241 tattaaatcg ctgaattttg atagccattc tgaagagtta tcttcaacta ctacactaac
      301 ttccattaat ttctcattaa tttccctttc gttcaaaaaa tatggttggc tttacaagca
      361 ttctatcata tgatagaatt aagataacat tcaaaaggag ataataaaaa tgcggcaagg
      421 tattcttaaa taaactgtca attagatagc gggaataatt aattaagcat ccttatttaa
      481 aataaggact ggttttttgt gcccagttta agaatacttt tatcatttta tcataaagca
      541 tctgtggcta tcagtgtgta gtatacagct atttttgtat taaaatccca gtgataagag
      601 tatttatcac tgggattttt tctgcttttt gagcttttga atggaggaaa taaaattgaa
      661 aattattaat atcggtatct tagcacatgt tgatgcagga aaaactactt tgacagaaag
      721 cttactatac agtagcggag caattaaaga gttaggaagt gtagatagcg gtacaacgaa
      781 aacggatact atgtttttgg aacgccagag aggtattact attcagaccg caataacatc
      841 ttttcaacgg gaaaatgtta aagtaaatat tgtagatact cctggacaca tggatttttt
      901 ggcagatgta taccgttcat tatctgtttt ggatggagct attttgctaa tctctgcaaa
      961 agatggagta cagtcacaaa ctcgtatact attccatgca cttagaaaga tgaacatacc
     1021 tataatattt tttattaaca aaattgatca aaatggaata aatttgccag atgtttatca
     1081 agatattaag gacaaacttt ctgacgacat cataattaag cagactgtga atctaaattt
     1141 gaaaccttat gtaatagatt atactgaacc agaacaatgg gagacagtaa ttgtgggaaa
     1201 tgattattta ttagaaaaat ataccattgg gaaaacattg aatattgcag aacttgaaaa
     1261 ggaggaaaac gaaagaattc aaagttgctc cttatatcct gtttatcacg gaagtgcaaa
     1321 gaataatatt ggaattaaac aacttataga ggtaattact agcaaattat tttcacccac
     1381 acaactcaat tcagataaac tttgtggaaa tgtttttaaa gtagaatatt cagatgatgg
     1441 tcaacggctt gtctatgtac gtctttatag tggaacgcta catttgcgag actcagtcaa
     1501 tatatcagaa aaggaaaaaa taaaagttac agaaatgtat acttcaataa atggagaatt
     1561 acgccagata gataaggcag agcctggtga gattattatt ttaaaaaatg agcttttaaa
     1621 actaaataac gtacttggag ataaaaaaag attaccacat agagaaattc ttgagaatcc
     1681 tcttcctatg ttacaaacaa caattgaacc atgtaaatca gtacaaagag aaaagttact
     1741 agatgcactt tttgaaatat ccgatagtga tccccttcta caatattatg tagatacagt
     1801 aactcacgaa attgtgctat cttttttagg tgaggtccaa atggaggtaa cttgtactct
     1861 gattcaagaa aaatatcata ttgagataga aacaagaaaa ccaactgtca tttatatgga
     1921 aagaccatta aaaaaatctg aatttaccat tgatatcgaa gtacctccaa atcctttctg
     1981 ggcttctatt ggtttatctg taacaccact tcctttgggt agtggcattc agtatgagag
     2041 cctggtttct ctaggttatt taaatcaatc atttcaaaat gcagttatgg aaggtatacg
     2101 ctatgggtgt gaacaaggat tgtacggttg gaaattaaca gactgtaaga tctgttttaa
     2161 gtatggtcta tattacagcc ctgtcagtac gccagcagat ttccgaatgc ttgcgcctat
     2221 tgtactagag caggctttta gaaagagtgg tacagagtta ttagagccat atcttagctt
     2281 cgaaatttat gtaccacaag aatatctttc gagagcatat aatgatgctt ccaaatattg
     2341 tgcaaatatt ttaaatacta agttaaaagg taacgaggtc attctcattg gtgaaattcc
     2401 agcccgttgt attcaagagt atcgaaacag tttaactttc tttacaaatg gacgcagtgt
     2461 ctgtttaaca gagttaaaag gttatcaggt tactaacatt aagtctgctt tccaaccacg
     2521 tcgtccaaat aatagaatag acaaagtaag gcatatgttt aataaaatca acttacattg
     2581 atagtgaact aaagagaaat ttttaaaatg aatattgagt tgttaattag aacaggagga
     2641 tatagatatt gtaaatacta ggtggatact gtgccctata tgtggcaata agacccgttt
     2701 aaaaatgagg gaagatactg aattaaaaaa tttccctcta ttttgtccta aatgcagaca
     2761 agaaatttta attgaaataa cgaagtttag aataactgta attacagagc cagacgcaaa
     2821 gacgcagagc cgataattcg agatatcaaa atctcatttt atcggctttt tcttttctat
     2881 gcataccatt gagcttagtt cttgatatcc tttataagaa aataagtgta ctgatttttt
     2941 ttgcagtagc tgtattacag tagacatccc tcaagcataa aaagtataca attaaaattc
     3001 aatacttgat tattgatgaa gtacagagtt actcgtcatt tcaaaactag tatatcagtc
     3061 aagtttttcc taaggaacaa aaacgaactt cgctatggga atcaaaaatt tttagtcgga
     3121 tgaagtgata tgcaataaat ccagaaaatt ttcccaacaa caaaaaatga actgtacttt
     3181 gcagcgataa gagtaaccaa agaactattt atcattcgct ctagttccta agtgtaacaa
     3241 agataaattc attttctatt tatgattaac aaaaatcaga aaaaattcat tacatctttg
     3301 taatcaatct ttcctgatag tattaattaa tccattgtgt attattgaac tagttaaatt
     3361 tacatttttc tccgtaaatt gcttgaatca ctttcccaat cgtcactaat tcatcttcat
     3421 ccagacaatc caactgtgct tctacttgaa gacgtttgga gcttttatga ctgttttctt
     3481 cccctaaaat aaatccatcc aaagaaatat ttagcaaagt cactaaatca tatacaacat
     3541 gaaaacttgg ctgttgtcct ttattttcaa tgttcgtcaa atagcgtggc gcaatctgga
     3601 tcattgatcc tacctgctca cgagtcaatc ctttactaag acgggcttct ttaatcgcaa
     3661 gacccaatgg tttgaaatca aaatttgata gagtagtttg ccatattctt gcacccaacg
//
LOCUS       DAFELK010000194         2976 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.137, whole genome shotgun sequence.
ACCESSION   DAFELK010000194
VERSION     DAFELK010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.137"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            297..1265
                     /locus_tag="LP433_003144"
     CDS             297..1265
                     /locus_tag="LP433_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL2007201.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1258..2289
                     /gene="vanA"
                     /locus_tag="LP433_003145"
     CDS             1258..2289
                     /gene="vanA"
                     /locus_tag="LP433_003145"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL2007202.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2295..2903
                     /locus_tag="LP433_003146"
     CDS             2295..2903
                     /locus_tag="LP433_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL2007203.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          885 a          569 c          719 g          803 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccg cttccagcga tgccagactt
       61 ggttgataaa aggaggtcct aagagatgta tataattttt taggaaaatc tcaaggttat
      121 ctttactttt tcttaggaaa ttaacaattt aatattaaga aacggctcgt tcttacacgg
      181 tagacttaat accgtaagaa cgagccgttt tcgttcttca gagaaagatt tgacaagatt
      241 accattggca tccccgtttt atttggtgcc tttcacagaa agggttggtc ttaattatga
      301 ataacatcgg cattactgtt tatggatgtg agcaggatga ggcagatgca ttccatgctc
      361 tttcgcctcg ctttggcgtt atggcaacga taattaacgc caacgtgtcg gaatccaacg
      421 ccaaatccgc gcctttcaat caatgtatca gtgtgggaca taaatcagag atttccgcct
      481 ctattcttct tgcgctgaag agagccggtg tgaaatatat ttctacccga agcatcggct
      541 gcaatcatat agatacaact gctgctaaga gaatgggcat cactgtcgac aatgtggcgt
      601 actcgccgga tagcgttgcc gattatacta tgatgctaat tcttatggca gtacgcaacg
      661 taaaatcgat tgtgcgctct gtggaaaaac atgatttcag gttggacagc gaccgtggca
      721 aggtactcag cgacatgaca gttggtgtgg tgggaacggg ccagataggc aaagcggtta
      781 ttgagcggct gcgaggattt ggatgtaaag tgttggctta tagtcgcagc cgaagtatag
      841 aggtaaacta tgtaccgttt gatgagttgc tgcaaaatag cgatatcgtt acgcttcatg
      901 tgccgctcaa tacggatacg cactatatta tcagccacga acaaatacag agaatgaagc
      961 aaggagcatt tcttatcaat actgggcgcg gtccacttgt agatacctat gagttggtta
     1021 aagcattaga aaacgggaaa ctgggcggtg ccgcattgga tgtattggaa ggagaggaag
     1081 agtttttcta ctctgattgc acccaaaaac caattgataa tcaattttta cttaaacttc
     1141 aaagaatgcc taacgtgata atcacaccgc atacggccta ttataccgag caagcgttgc
     1201 gtgataccgt tgaaaaaacc attaaaaact gtttggattt tgaaaggaga caggagcatg
     1261 aatagaataa aagttgcaat actgtttggg ggttgctcag aggagcatga cgtatcggta
     1321 aaatctgcaa tagagatagc cgctaacatt aataaagaaa aatacgagcc gttatacatt
     1381 ggaattacga aatctggtgt atggaaaatg tgcgaaaaac cttgcgcgga atgggaaaac
     1441 gacaattgct attcagctgt actctcgccg gataaaaaaa tgcacggatt acttgttaaa
     1501 aagaaccatg aatatgaaat caaccatgtt gatgtagcat tttcagcttt gcatggcaag
     1561 tcaggtgaag atggatccat acaaggtctg tttgaattgt ccggtatccc ttttgtaggc
     1621 tgcgatattc aaagctcagc aatttgtatg gacaaatcgt tgacatacat cgttgcgaaa
     1681 aatgctggga tagctactcc cgccttttgg gttattaata aagatgatag gccggtggca
     1741 gctacgttta cctatcctgt ttttgttaag ccggcgcgtt caggctcatc cttcggtgtg
     1801 aaaaaagtca atagcgcgga cgaattggac tacgcaattg aatcggcaag acaatatgac
     1861 agcaaaatct taattgagca ggctgtttcg ggctgtgagg tcggttgtgc ggtattggga
     1921 aacagtgccg cgttagttgt tggcgaggtg gaccaaatca ggctgcagta cggaatcttt
     1981 cgtattcatc aggaagtcga gccggaaaaa ggctctgaaa acgcagttat aaccgttccc
     2041 gcagaccttt cagcagagga gcgaggacgg atacaggaaa cggcaaaaaa aatatataaa
     2101 gcgctcggct gtagaggtct agcccgtgtg gatatgtttt tacaagataa cggccgcatt
     2161 gtactgaacg aagtcaatac tctgcccggt ttcacgtcat acagtcgtta tccccgtatg
     2221 atggccgctg caggtattgc acttcccgaa ctgattgacc gcttgatcgt attagcgtta
     2281 aaggggtgat aagcatggaa ataggattta cttttttaga tgaaatagta cacggtgttc
     2341 gttgggacgc taaatatgcc acttgggata atttcaccgg aaaaccggtt gacggttatg
     2401 aagtaaatcg cattgtaggg acatacgagt tggctgaatc gcttttgaag gcaaaagaac
     2461 tggctgctac ccaagggtac ggattgcttc tatgggacgg ttaccgtcct aagcgtgctg
     2521 taaactgttt tatgcaatgg gctgcacagc cggaaaataa cctgacaaag gaaagttatt
     2581 atcccaatat tgaccgaact gagatgattt caaaaggata cgtggcttca aaatcaagcc
     2641 atagccgcgg cagtgccatt gatcttacgc tttatcgatt agacacgggt gagcttgtac
     2701 caatggggag ccgatttgat tttatggatg aacgctctca tcatgcggca aatggaatat
     2761 catgcaatga agcgcaaaat cgcagacgtt tgcgctccat catggaaaac agtgggtttg
     2821 aagcatatag cctcgaatgg tggcactatg tattaagaga cgaaccatac cccaatagct
     2881 attttgattt ccccgttaaa taaactttta accgttgcac ggacaaacta tataagcggt
     2941 tctgttgcaa agttttaaat aaagaataaa atccct
//
LOCUS       DAFELK010000195         1155 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.168, whole genome shotgun sequence.
ACCESSION   DAFELK010000195
VERSION     DAFELK010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.168"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            <1..211
                     /locus_tag="LP433_003147"
     CDS             <1..211
                     /locus_tag="LP433_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2007204.1"
                     /translation="LFDSRFKTLQQNRAKHKNLHGLMLETQDNNLIACKFYHNCGFKI
                     GSVDTMLYANFENNFEKAVFWYLRF"
     gene            304..1098
                     /locus_tag="LP433_003148"
                     /note="aph(3')-IIIa"
     CDS             304..1098
                     /locus_tag="LP433_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL2007205.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          367 a          194 c          283 g          311 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccgg gcaaagcata aaaacttgca
       61 tggactaatg cttgaaaccc aggacaataa ccttatagct tgtaaattct atcataattg
      121 tggtttcaaa atcggctccg tcgatactat gttatacgcc aactttgaaa acaactttga
      181 aaaagctgtt ttctggtatt taaggtttta gaatgcaagg aacagtgaat tggagttcgt
      241 cttgttataa ttagcttctt ggggtatctt taaatactgt agaaaagagg aaggaaataa
      301 taaatggcta aaatgagaat atcaccggaa ttgaaaaaac tgatcgaaaa ataccgctgc
      361 gtaaaagata cggaaggaat gtctcctgct aaggtatata agctggtggg agaaaatgaa
      421 aacctatatt taaaaatgac ggacagccgg tataaaggga ccacctatga tgtggaacgg
      481 gaaaaggaca tgatgctatg gctggaagga aagctgcctg ttccaaaggt cctgcacttt
      541 gaacggcatg atggctggag caatctgctc atgagtgagg ccgatggcgt cctttgctcg
      601 gaagagtatg aagatgaaca aagccctgaa aagattatcg agctgtatgc ggagtgcatc
      661 aggctctttc actccatcga catatcggat tgtccctata cgaatagctt agacagccgc
      721 ttagccgaat tggattactt actgaataac gatctggccg atgtggattg cgaaaactgg
      781 gaagaagaca ctccatttaa agatccgcgc gagctgtatg attttttaaa gacggaaaag
      841 cccgaagagg aacttgtctt ttcccacggc gacctgggag acagcaacat ctttgtgaaa
      901 gatggcaaag taagtggctt tattgatctt gggagaagcg gcagggcgga caagtggtat
      961 gacattgcct tctgcgtccg gtcgatcagg gaggatatcg gggaagaaca gtatgtcgag
     1021 ctattttttg acttactggg gatcaagcct gattgggaga aaataaaata ttatatttta
     1081 ctggatgaat tgttttagta cctagattta gatgtcggtt ctgttgcaaa gttttaaatc
     1141 tactatcaaa taagg
//
LOCUS       DAFELK010000196         1135 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR44453_1
            SAMN20573713-rid13348553.guided.171, whole genome shotgun sequence.
ACCESSION   DAFELK010000196
VERSION     DAFELK010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573713
            Sequence Read Archive: SRR16917309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177032.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177032.1
            Genome Coverage       :: 279x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 12:31:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,149
            CDSs (total)                      :: 3,089
            Genes (coding)                    :: 3,003
            CDSs (with protein)               :: 3,003
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 14 of 86
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573713-rid13348553.guided.171"
                     /isolate="PR44453_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-12"
                     /collected_by="University of Michigan"
     gene            267..1106
                     /locus_tag="LP433_003149"
                     /note="aph(2'')-Ia"
     CDS             267..1106
                     /locus_tag="LP433_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBL2007206.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEF
                     MRV"
BASE COUNT          479 a           87 c          191 g          378 t
ORIGIN      
        1 agggatttta ttctttattt aaaactttgc aacagaaccg tacaagatat attaaattga
       61 tttttgaatt tttgaaaaaa gaaagaaatg ctaatgcagt tattttagac cctcataaaa
      121 ataatccaag agcaataagg gcataccaaa aatctggttt tagaattatt gaagatttgc
      181 cagaacatga attacacgag ggcaaaaaag aagattgtta tttaatggaa tatagatatg
      241 atgataatgc cacaaatgtt aaggcaatga aatatttaat tgagcattac tttgataatt
      301 tcaaagtaga tagtattgaa ataatcggta gtggttatga tagtgtggca tatttagtta
      361 ataatgaata catttttaaa acaaaattta gtactaataa gaaaaaaggt tatgcaaaag
      421 aaaaagcaat atataatttt ttaaatacaa atttagaaac taatgtaaaa attcctaata
      481 ttgaatattc gtatattagt gatgaattat ctatactagg ttataaagaa attaaaggaa
      541 cttttttaac accagaaatt tattctacta tgtcagaaga agaacaaaat ttgttaaaac
      601 gagatattgc cagtttttta agacaaatgc acggtttaga ttatacagat attagtgaat
      661 gtactattga taataaacaa aatgtattag aagagtatat attgttgcgt gaaactattt
      721 ataatgattt aactgatata gaaaaagatt atatagaaag ttttatggaa agactaaatg
      781 caacaacagt ttttgagggt aaaaagtgtt tatgccataa tgattttagt tgtaatcatc
      841 tattgttaga tggcaataat agattaactg gaataattga ttttggagat tctggaatta
      901 tagatgaata ttgtgatttt atatacttac ttgaagatag tgaagaagaa ataggaacaa
      961 attttggaga agatatatta agaatgtatg gaaatataga tattgagaaa gcaaaagaat
     1021 atcaagatat agttgaagaa tattatccta ttgaaactat tgtttatgga attaaaaata
     1081 ttaaacagga atttatgaga gtgtaaaata ttttgtgtaa atagaaaaaa ggaag
//
